BioRxiv 2025-01-22 Papers

标题	作者	PDF链接	代码仓库	Title
视觉变化检测中起始优势的事件相关电位研究	Van Pelt, J.	PDF	N/A	An Event-Related Potential Study of Onset Primacy in Visual Change Detection
通过将成纤维细胞纳入杜氏肌营养不良症（Duchenne Muscular Dystrophy, DMD）的MYOrganoids模型中，研究发现疾病恶化现象，揭示了微抗肌萎缩蛋白（microdystrophin）治疗效果的局限性。	Palmieri, L.	PDF	N/A	Disease exacerbation by fibroblast inclusion in Duchenne Muscular Dystrophy MYOrganoids reveals limitations of microdystrophin therapeutic efficacy
使用尺寸排阻色谱法和密度梯度超速离心从小体积血浆中分离小细胞外囊泡：一项比较研究	Kong, F.	PDF	N/A	Isolating Small Extracellular Vesicles from Small Volumes of Blood Plasma using size exclusion chromatography and density gradient ultracentrifugation: A Comparative Study
荧光生成、亚单周转监测涉及NAD(P)H的酶反应为微滴中生物催化剂的定向超高通量进化提供了一个通用平台。	Penner, M.	PDF	N/A	Fluorogenic, sub-single-turnover monitoring of enzymatic reactions involving NAD(P)H provides a generalised platform for directed ultrahigh throughput evolution of biocatalysts in microdroplets
人的声音与全身的运动相协调。	Pouw, W.	PDF	N/A	The human voice aligns with whole-body kinetics
针对持续FGF23-ERK信号通路的基因治疗可减轻肾脏炎症	Salas-Bastos, A.	PDF	N/A	Gene therapy targeting sustained FGF23-ERK signaling alleviates kidney inflammation
细菌中一般应激反应启动的通用机制	Baral, R.	PDF	N/A	A General Mechanism for Initiating the General Stress Response in Bacteria
微生物群落结构受到与噬菌体抗性相关的宿主密度增加的影响。	Castledine, M.	PDF	N/A	Microbial community structure is affected by phage-resistance associated increases in host density
EPHA4信号传导失调与异常运动及特发性脊柱侧凸的发展相关联	Wang, L.	PDF	N/A	EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis
序列组成和保守性预测转座因子的表型相关性	Cerruti, Y.	PDF	N/A	Sequence composition and conservation predict the phenotypic relevance of transposable elements
升高的锥体细胞放电通过COX-2衍生的前列腺素E2信号传导协调小动脉血管收缩。	Le Gac, B.	PDF	N/A	Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling
一段时期性的巨大基因组重排爆发与非海洋环节动物的起源	Vargas-Chavez, C.	PDF	N/A	An episodic burst of massive genomic rearrangements and the origin of non-marine annelids
对高表达甲状腺球蛋白基因的延迟共转录剪接进行显微镜分析	Ullrich, S.	PDF	N/A	Microscopy analysis of delayed co-transcriptional splicing in highly expressed thyroglobulin gene
健康与肥胖小鼠肝脏中饥饿响应代谢网络的结构稳健性与时间脆弱性	Morita, K.	PDF	N/A	Structural robustness and temporal vulnerability of the starvation-responsive metabolic network in liver of healthy and obese mice
使用微生物酶混合物进行多糖定量	Pontrelli, S.	PDF	N/A	Polysaccharide quantification using microbial enzyme cocktails
一种快速且高效的基因敲除方法应用于领鞭毛虫Salpingoeca rosetta，揭示了领鞭毛虫多细胞发育的遗传机制。	Combredet, C.	PDF	N/A	A fast and robust gene knockout method for Salpingoeca rosetta clarifies the genetics of choanoflagellate multicellular development
PA28γ通过C1QBP提升线粒体功能，从而促进肿瘤的恶性进展。	Wang, J.	PDF	N/A	PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
一种新的醌类生物合成途径揭示了有氧代谢的进化	Elling, F. J.	PDF	N/A	A novel quinone biosynthetic pathway illuminates the evolution of aerobic metabolism
在东亚亚热带地区，三种鼠耳蝠（Myotis）的觅食生态位划分及毛足鼠耳蝠（Myotis pilosus）对海洋鱼类的摄食研究	Wei, X.	PDF	N/A	Foraging niche partitioning of three Myotis bat species and marine fish consumption by Myotis pilosus in a subtropical East Asian region
细胞几何形状、微管偏转和方向依赖性动态不稳定性在皮层阵列组织中的冲突作用	Tian, T. Y. Y.	PDF	N/A	Conflicting roles of cell geometry, microtubule deflection and orientation-dependent dynamic instability in cortical array organization
黑水虻的控制性和一夫多妻制交配：利用定量遗传设计推进育种计划	Jensen, K.	PDF	N/A	Controlled and polygynous mating in the black soldier fly: advancing breeding programs utilizing quantitative genetic designs
加拉帕戈斯群岛Scalesia适应性辐射中的基因组稳定性：尽管存在杂交和生态位转变，转座因子仍持续积累	Cerca, J.	PDF	N/A	Genomic stability in the Galapagos Scalesia adaptive radiation: Consistent transposable element accumulation despite hybridization and ecological niche shifts
以下是这段英文的中文翻译：

“关于Jyvaskylavirus的基因组和结构见解，这是首个从芬兰分离出的巨型病毒”

翻译说明： - “Genomic and structural insights” 翻译为 “基因组和结构见解” - “Jyvaskylavirus” 是病毒名称，保留原文 - “the first giant virus isolated from Finland” 翻译为 “首个从芬兰分离出的巨型病毒”

这段文字描述了对Jyvaskylavirus病毒的研究，重点是其基因组和结构特征，并强调这是第一个在芬兰发现的巨型病毒。 | de Freitas Almeida, G. M. | PDF | N/A | Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland | | 主肺动脉的本构神经网络：探索未知 | Vervenne, T. | PDF | N/A | Constitutive neural networks for main pulmonary arteries: Discovering the undiscovered | | 阿利效应、产卵不同步性以及常见大规模产卵珊瑚中的混合繁殖模式 | Ricardo, G. F. | PDF | N/A | Allee effects, spawning asynchrony, and mixed reproductive modes in a common mass spawning coral | | 将生物分割数据集公平地（FAIRly）存储 | Ho, E. M. L. | PDF | N/A | Depositing biological segmentation datasets FAIRly | | 量化DIA-MS数据集中之前未被量化的约75-95%的肽段 | Saxena, G. | PDF | N/A | Quantifying the ~75-95% of Peptides in DIA-MS Datasets that were not Previously Quantified | | DUX4诱导的HSATII RNA积累驱动蛋白质聚集，影响RNA加工途径。 | Arends, T. | PDF | N/A | DUX4-induced HSATII RNA accumulation drives protein aggregation impacting RNA processing pathways. | | 一种用于预测蛋白质内在无序区域相互作用的深度学习方法 | Majila, K. | PDF | N/A | A deep learning method for predicting interactions for intrinsically disordered regions of proteins | | I2SIM：通过图像干扰和空间频谱优化提升高保真各向同性超分辨率 | He, E. | PDF | N/A | I2SIM: Boosting High-Fidelity Isotropic Super-Resolution with Image Interference and Spatial-Spectrum Optimization | | Nde1促进Lis1与全长自抑制状态的人源Dynein-1结合 | Yang, J. | PDF | N/A | Nde1 Promotes Lis1 Binding to Full-Length Autoinhibited Human Dynein-1 | | 在盲人视网膜中利用超敏感人类TRPV1通道进行红外光检测的工程研究 | Chevalier, M. | PDF | N/A | Engineering Infrared Light Detection in Blind Human Retina Using Ultrasensitive Human TRPV1 Channels | | 日本树蛙（Dryophytes japonicus）蝌蚪对多种蜻蜓若虫的捕食者诱导尾部颜色变化 | Noda, A. | PDF | N/A | Predator-Induced Tail Coloration Toward Diverse Dragonfly Nymphs in Tadpoles of the Japanese Tree Frog (Dryophytes japonicus) | | D类β-内酰胺酶中的标准化残基编号和二级结构命名法 | Stasyuk, A. | PDF | N/A | Standardized Residue Numbering and Secondary Structure Nomenclature in the Class D β-Lactamases | | 人乳寡糖通过梭菌属物种的代谢抑制炎症和病原体生长 | Chapman, J. A. | PDF | N/A | Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth | | 一种便捷的宏基因组学策略能够更好地表征无脊椎动物批量样本。 | Callens, M. | PDF | N/A | An accessible metagenomic strategy allows for better characterization of invertebrate bulk samples | | 全基因组分析揭示了突变表型在结核分枝杆菌耐药性出现中的作用 | Zein-Eddine, R. | PDF | N/A | Genome wide analyses reveal the role of mutator phenotypes in the emergence of drug resistance in Mycobacterium tuberculosis | | 基因组测序、分子标记开发及重要经济脆弱树种无忧树（Saraca asoca (Roxb.) W.J de Wilde）的遗传多样性评估 | P, M. | PDF | N/A | Genome Sequencing, Molecular Marker Development and Genetic Diversity Assessment of Economically Important Vulnerable Tree Species Saraca asoca (Roxb.) W.J de Wilde | | AI.zymes - 一个用于进化酶设计的模块化平台 | Merlicek, L. P. | PDF | N/A | AI.zymes - A modular platform for evolutionary enzyme design | | 以下是这段文字的中文翻译：

微泡空化在治疗诊断超声介导的血脑屏障开放和基因递送中的表征

一种用于双光子荧光显微镜分割的自监督深度学习流程

翻译说明： 1. "self-supervised" 翻译为 "自监督"，这是深度学习中的一种训练方式 2. "deep learning pipeline" 翻译为 "深度学习流程"，指一系列的处理步骤 3. "segmentation" 翻译为 "分割"，这是图像处理中的常用术语 4. "two-photon fluorescence microscopy" 翻译为 "双光子荧光显微镜"，这是一种先进的显微成像技术

这个标题描述了一种用于处理双光子荧光显微镜图像的自监督深度学习系统，主要用于图像分割任务。 | Ntiri, E. E. | PDF | N/A | A self-supervised deep learning pipeline for segmentation in two-photon fluorescence microscopy | | 自闭症相关基因Tbr1的缺失会破坏社会情感行为期间前额叶集合体的预测和编码功能。 | Turner, M. | PDF | N/A | Loss of the autism associated gene Tbr1 disrupts prediction and encoding by prefrontal ensembles during socioemotional behaviors | | 术中人类微电极记录的参数化：将动作电位形态与脑解剖结构联系起来 | Baker, M. R. | PDF | N/A | Parameterization of intraoperative human microelectroderecordings: Linking action potential morphology to brainanatomy | | 火花随距离减弱：不同经颅电刺激技术下电场分布对全局运动感知的影响 | Pavan, A. | PDF | N/A | Sparks fade with distance: The effect of electric field distribution on global motion perception using different tES techniques | | 神经网络爆发对功能连接性的影响 | Ramstad, O. H. | PDF | N/A | Influence of neural network bursts on functional connectivity | | 大麻素对中央杏仁核群体动态在威胁调查期间的调节作用 | Yasmin, F. | PDF | N/A | Cannabinoid Modulation of Central Amygdala Population Dynamics During Threat Investigation | | 多纤毛动态转导Shh信号以调节脉络丛功能 | He, L. | PDF | N/A | Multicilia dynamically transduce Shh signaling to regulate choroid plexus functions | | 在羽虱多样化的过程中，独立且重复地获得了内共生细菌。 | Soto-Patino, J. | PDF | N/A | Independent and repeated acquisition of endosymbiotic bacteria across the diversification of feather lice | | 关于拟南芥种质在蚜虫选择压力下可遗传变化的证据较弱 | Schmid, M. W. | PDF | N/A | Weak evidence for heritable changes in response to selection by aphids in Arabidopsis accessions | | 自闭症相关基因与邻近长链非编码RNA在关键基因调控网络上的汇聚 | Andersen, R. | PDF | N/A | Autism-Associated Genes and Neighboring lncRNAs Converge on Key Gene Regulatory Networks | | 比较评估重建人类病毒基因组的计算方法 | Sousa, M. J. P. | PDF | N/A | Comparative evaluation of computational methods for reconstruction of human viral genomes | | 混合生成模型：桥接机器学习与生物物理学，拓展RNA功能多样性 | Opuu, V. | PDF | N/A | Hybrid Generative Model: Bridging Machine Learning and Biophysics to Expand RNA Functional Diversity | | PI3K调控TAZ/YAP和mTORC1信号轴，这些信号轴可以被协同靶向。 | Garcia, K. C. | PDF | N/A | PI3K regulates TAZ/YAP and mTORC1 axes that can be synergistically targeted | | 阿尔茨海默病中突触小泡蛋白2A在细胞外囊泡和大脑中的水平降低——与Aβ、tau蛋白和突触素的关系 | Nussbaumer, J. | PDF | N/A | Reduced levels of synaptic vesicle protein 2A in the extracellular vesicles and brain of Alzheimer's disease- associations with Aβ, tau and synaptophysin | | 测量空间排序的强度 | Goel, N. | PDF | N/A | Measuring the Strength of Spatial Sorting | | 在性别特定的3D生物打印肺动脉外膜模型中，女性成纤维细胞的激活是由雌激素介导的。 | Mueller, M. C. | PDF | N/A | Female fibroblast activation is estrogen-mediated in sex-specific 3D-bioprinted pulmonary artery adventitia models | | 膜波动与脂质曲率之间的耦合导致线粒体膜中心磷脂的瞬时局部富集。 | Lee, C. T. | PDF | N/A | Coupling between membrane undulations and lipid curvature leads to transient local enrichment of cardiolipin in mitochondrial membranes | | 染色质凝聚体的多尺度结构合理化相分离及材料特性 | Zhou, H. | PDF | N/A | Multi-scale structure of chromatin condensates rationalizes phase separation and material properties | | 了解ProQ蛋白的RNA伴侣活性 | Singh, S. | PDF | N/A | Understanding RNA Chaperone Activity of ProQ Protein | | 一项以领域为中心的系统方法揭示了与干旱胁迫下高粱生长和发育相关的mRNA共价修饰。 | Yu, L. | PDF | N/A | A field-focused systems approach reveals mRNA covalent modifications linked to sorghum growth and development under drought stress | | 叶片渗透势的样本量是否会影响其与棉花产量的关系？ | Dong, X. | PDF | N/A | Does sample size of leaf osmotic potential affect its relationship with cotton yield? | | 微生理系统体外/体内转化操作条件的合理设计系统生物学框架 | Cadavid, J. L. | PDF | N/A | Systems biology framework for rational design of operational conditions for in vitro / in vivo translation of microphysiological systems | | 加权基因共表达网络分析揭示了长期感染约翰病的德西牛中的关键基因和长链非编码RNA | Sahu, A. | PDF | N/A | Weighted gene co-expression network analysis reveals key genes and lncRNAs in desi cattle chronically infected with Johne's disease | | 脑池造瘘术有助于清除创伤性脑损伤患者脑脊液中的代谢废物。 | He, W. | PDF | N/A | Cisternostomy facilitates clearance of metabolic waste from cerebrospinal fluid in patients with traumatic brain injury | | Scg2驱动皮质脊髓回路与脊髓前运动中间神经元的重组，以促进中风后运动功能的恢复。 | Sato, T. | PDF | N/A | Scg2 drives reorganization of the corticospinal circuit with spinal premotor interneurons to recover motor function after stroke | | 在大鼠中，导水管周围灰质中的Fos表达与心理社会压力诱导的可卡因寻求行为相关，而腹内侧下丘脑中的Fos表达则与此无关。 | Hinds, N. M. | PDF | N/A | Fos expression in the periaqueductal gray, but not the ventromedial hypothalamus, is correlated with psychosocial stress-induced cocaine-seeking behavior in rats | | 以下是这段文字的中文翻译：

从皮层兴奋性神经元中去除Miro1后引发的焦虑相关行为

翻译说明： - "Anxiety-associated behaviors" 翻译为 "焦虑相关行为" - "following ablation of" 翻译为 "去除...后引发的" 或 "切除...后导致的" - "Miro1" 是一个基因名称，通常不翻译 - "cortical excitatory neurons" 翻译为 "皮层兴奋性神经元"

半翅目昆虫生物钟和光输入途径基因的进化

翻译说明： - "Evolution" 翻译为“进化” - "circadian clock" 翻译为“生物钟” - "light-input pathway genes" 翻译为“光输入途径基因” - "Hemiptera" 翻译为“半翅目”（昆虫纲的一个目，包括蝉、蚜虫等）

粗糙脉孢菌细胞壁重塑同种异体识别检查点等位基因特异性所需区域的鉴定

翻译说明： - "Identification" 译为 "鉴定" - "regions required for" 译为 "所需区域" - "allelic specificity" 译为 "等位基因特异性" - "cell wall remodeling" 译为 "细胞壁重塑" - "allorecognition checkpoint" 译为 "同种异体识别检查点" - "Neurospora crassa" 译为 "粗糙脉孢菌"

对来自高温泻湖的新型耐热广盐性单细胞海洋蓝藻 Cyanobacterium sp. DS4 的比较基因组分析

翻译说明： 1. "Comparative genomic analysis" 翻译为“比较基因组分析”。 2. "novel heat-tolerant and euryhaline strain" 翻译为“新型耐热广盐性菌株”。 3. "unicellular marine cyanobacterium" 翻译为“单细胞海洋蓝藻”。 4. "high-temperature lagoon" 翻译为“高温泻湖”。

小鼠单细胞长读长剪接图谱（Ouro-Seq）

如果需要进一步解释或调整，请告诉我！ | An, H. | PDF | N/A | Mouse Single-Cell Long-Read Splicing Atlas by Ouro-Seq | | 单条哺乳动物染色质纤维上普遍存在且程序化的核小体扭曲模式 | Yang, M. G. | PDF | N/A | Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers | | 调节老年人CD8+ T细胞衰老的表观遗传机制 | Turano, P. S. | PDF | N/A | Epigenetic mechanisms regulating CD8+ T cell senescence in aging humans | | 低水平污染混淆了群体基因组分析。 | Ward, A. | PDF | N/A | Low level contamination confounds population genomic analysis | | 基于质谱的蛋白质组学中复杂肽形通用谱图注释器 | Schulte, D. | PDF | N/A | A universal spectrum annotator for complex peptidoforms in mass spectrometry-based proteomics | | 标题：Phyla：迈向系统发育推断的基础模型

在生物信息学领域，系统发育推断（Phylogenetic Inference）是研究物种间进化关系的重要方法。近年来，随着人工智能技术的快速发展，研究人员开始探索如何利用深度学习等先进技术来构建更高效、更准确的系统发育推断模型。本文将介绍一个名为“Phyla”的项目，该项目旨在开发一个基础模型（Foundation Model），以支持更广泛、更深入的系统发育研究。

1. 背景与动机

系统发育推断是通过分析物种的遗传数据（如DNA序列）来构建进化树（Phylogenetic Tree）的过程。传统的系统发育方法通常依赖于最大似然法（Maximum Likelihood）或贝叶斯推断（Bayesian Inference），这些方法在处理大规模数据集时往往计算复杂度高，且难以捕捉复杂的进化模式。

随着基因组数据的爆炸式增长，传统的系统发育方法面临着巨大的挑战。因此，开发一种能够高效处理大规模数据、并能够自动学习进化模式的系统发育推断模型变得尤为重要。

2. Phyla项目的目标

Phyla项目的核心目标是构建一个基础模型，该模型能够作为系统发育推断的通用框架，适用于各种不同类型的生物数据和进化场景。具体来说，Phyla项目旨在实现以下几个目标：

高效性：通过深度学习技术，显著提高系统发育推断的计算效率，使其能够处理大规模基因组数据。
准确性：利用深度学习的强大表达能力，捕捉复杂的进化模式，提高推断结果的准确性。
通用性：开发一个通用的基础模型，能够适应不同的生物数据类型（如DNA、RNA、蛋白质序列）和不同的进化场景（如物种分化、基因家族进化等）。

3. 技术路线

Phyla项目的技术路线主要包括以下几个步骤：

数据预处理：对输入的生物数据进行预处理，包括序列比对、特征提取等步骤，以便为深度学习模型提供高质量的输入数据。
模型设计：设计一个深度神经网络模型，该模型能够自动学习序列之间的进化关系，并生成相应的系统发育树。模型可能包括卷积神经网络（CNN）、循环神经网络（RNN）或Transformer等架构。
训练与优化：利用大规模的系统发育数据集对模型进行训练，并通过优化算法（如梯度下降法）不断调整模型参数，以提高推断的准确性。
模型评估：在多个标准数据集上对模型进行评估，比较其与传统系统发育方法的性能差异，确保模型在实际应用中的有效性。

4. 预期成果

Phyla项目的预期成果包括：

开源模型：将开发的基础模型开源，供全球研究人员使用和进一步改进。
工具包：提供一个用户友好的工具包，使生物学家能够轻松地使用该模型进行系统发育推断。
应用案例：通过多个实际案例展示该模型在不同生物数据上的应用效果，推动系统发育研究的发展。

5. 结论

Phyla项目代表了系统发育推断领域的一次重要尝试，通过引入深度学习技术，有望显著提升系统发育推断的效率和准确性。随着项目的不断推进，我们期待Phyla能够成为系统发育研究中的一项重要工具，为理解生物进化提供新的视角和方法。

一种简单且可扩展的Marchantia polymorpha（地钱）切段转化方法

翻译说明： 1. "A Simple and Scalable" 翻译为 "一种简单且可扩展的"，描述了该方法的特点。 2. "Chopped-Thallus Transformation Method" 翻译为 "切段转化方法"，其中 "Chopped-Thallus" 指的是将地钱的叶状体切碎后进行转化。 3. "Marchantia polymorpha" 是植物学名，通常翻译为 "地钱" 或 "多形地钱"。

这个标题描述了一种用于地钱遗传转化的新方法，该方法简单易行且适用于大规模操作。 | Batth, R. | PDF | N/A | A Simple and Scalable Chopped-Thallus Transformation Method for Marchantia polymorpha | | 解码调控小麦花序发育的细胞转录调控网络 | Liu, X. | PDF | N/A | Decoding cellular transcriptional regulatory networks governing wheat inflorescence development | | CYP722A1驱动的卡拉克通酸16-羟基化调控拟南芥的花期转换 | Kuno, M. | PDF | N/A | CYP722A1-driven 16-hydroxylation of carlactonoic acid regulates the floral transition in Arabidopsis | | 埃及蝗虫（Anacridium aegyptium）行走过程中的非线性运动模式：详细案例研究 | Tozzi, A. | PDF | N/A | Nonlinear locomotion patterns in the Egyptian Locust (Anacridium aegyptium) during walking: a detailed case study | | 致癌应激是一种由未折叠蛋白反应驱动的新型免疫原性信号，并被中性粒细胞检测到。 | Debiesse, A. | PDF | N/A | Oncogenic Stress is a Novel Immunogenic Signal Driven by the Unfolded Protein Response and Detected by Neutrophils | | 通过分组简化物种相互作用矩阵：影响和响应的最佳分组不同 | Brown, C. R. P. | PDF | N/A | Simplifying species interaction matrices by grouping: optimal groupings differ between effects and responses | | 酮体β-羟基丁酸不会延长寿命，但在食物受限的水蚤中上调了繁殖力，并具有跨代效应。 | C. Pearson, A. C. | PDF | N/A | Ketone body b-Hydroxybutyrate does not extend lifespan, but upregulates fecundity in food-limited Daphnia, with a transgenerational effect | | 多功能弯曲磁铁光束线配备毛细管光学元件，用于组织切片中金属的X射线荧光研究 | Roter, B. | PDF | N/A | Multifunctional bending magnet beamline with a capillary optic for X-ray fluorescence studies of metals in tissue sections | | 一种明亮的合成近红外荧光素增强了使用萤火虫荧光素酶进行深层组织生物发光成像的能力。 | Saito-Moriya, R. | PDF | N/A | A bright synthetic near-infrared luciferin enhances the capabilities of deep-tissue bioluminescence imaging using firefly luciferases | | 当邻居发挥作用时：对影响癌症驱动突变效应的蛋白质相互作用的系统级分析 | Vital, M. F. | PDF | N/A | When neighbours play a role: a systems-level analysis of protein interactions conditioning cancer driver mutation effects | | SCAN-ACT：通过单细胞转录组学发现适应性T细胞疗法的靶点 | Testa, S. | PDF | N/A | SCAN-ACT: Adoptive T Cell Therapy Target Discovery Through Single-Cell Transcriptomics | | 免疫细胞线粒体表型在线粒体疾病中基本保持不变，并不反映疾病的严重程度。 | Liu, C. C. | PDF | N/A | Immune cell mitochondrial phenotypes are largely preserved in mitochondrial diseases and do not reflect disease severity | | 物种引入对相互作用的食果鸟类和肉质果植物性状多样性的影响取决于本地性状多样性 | Nowak, L. | PDF | N/A | Impacts of species introductions on the trait diversity of interacting avian frugivores and fleshy-fruited plants depend on native trait diversity | | 从二倍体到多倍体转变过程中超级基因的命运 | Mora Carrera, E. | PDF | N/A | Fate of a supergene in the shift from diploidy to polyploidy | | 丙酮酸及相关能量代谢物调节对青光眼高遗传风险的抵抗力 | Li, K. | PDF | N/A | Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma | | GETgene-AI：一个用于优先考虑可操作癌症药物靶点的框架 | Gu, A. | PDF | N/A | GETgene-AI: A Framework for Prioritizing Actionable Cancer Drug Targets | | 补充游离酸β-羟基丁酸并不能像生酮饮食那样改善雄性小鼠中由硫酸葡聚糖钠诱导的结肠炎。 | Toivio, L. | PDF | N/A | Free acid β-hydroxybutyrate supplementation does not ameliorate dextran sodium sulfate-induced colitis similar to ketogenic diet in male mice | | 抑制EZH2通过调节滑膜和巨噬细胞炎症、轴突导向以及破骨细胞生成，缓解实验性小鼠模型中的骨关节炎和疼痛 | Brochard, S. | PDF | N/A | Inhibiting EZH2 Alleviates Osteoarthritis and Pain in an Experimental Murine Model Through Modulating Synovial and Macrophage Inflammation, Axon Guidance, and Osteoclastogenesis | | 从横截面数据中表征正在进行的大脑老化 | Smith, S. M. | PDF | N/A | Characterising ongoing brain aging from cross-sectional data | | “元分析一路到底：神经影像元分析概览” | Oudyk, K. M. | PDF | N/A | Meta all the way down: An overview of neuroimaging meta-analyses | | 多模态神经影像学揭示了新发帕金森病患者中左旋多巴诱导的运动障碍的独特特征 | Shukla, S. | PDF | N/A | Multimodal Neuroimaging Reveals Distinct Characteristics of Levodopa-Induced Dyskinesias in de novo Parkinsons Disease Patients | | 代谢酶GYS1在细胞核内与NONO/p54nrb结合，以时空调节糖原生成和肌原性分化。 | Peng, S. | PDF | N/A | The metabolic enzyme GYS1 condenses with NONO/p54nrb in the nucleus to spatiotemporally regulate glycogenesis and myogenic differentiation | | 一种利用D-半乳糖诱导间充质干细胞衰老趋势的方法 | Ji, X. | PDF | N/A | A method for inducing a senescence trend in mesenchymal stem cells using D-galactose | | 病毒感染显著降低昆虫的适应性：一项元分析 | Cesar, C. S. | PDF | N/A | Virus infection significantly decreases insect fitness: a meta-analysis | | 遥测验证背甲微化学：互补工具重建濒危大西洋鲟鱼种群的迁徙生活史 | Ingram, E. C. | PDF | N/A | Telemetry-validation of dorsal scute microchemistry: complementary tools reconstruct the migratory life-history of an endangered population of Atlantic Sturgeon | | 通过对家短尾负鼠（Monodelphis domestica）的毒液抗性进行表征，我们获得了关于哺乳动物血液生理学的新见解。 | Holding, M. L. | PDF | N/A | Characterizing venom resistance in Monodelphis domestica yields new insights into mammalian blood physiology | | 《新热带地区闭鞘姜科的修订：六十年分类学奋斗的成果》 | Maas, P. J. M. | PDF | N/A | A revision of the Neotropical Costaceae: results from sixty years of taxonomic struggle | | 迈向使用快速且内存高效算法进行全基因组多基因评分推断 | Zabad, S. | PDF | N/A | Towards whole-genome inference of polygenic scores with fast and memory-efficient algorithms | | 利用片段化纵向数据估算育种田中果树的生长曲线：以柑橘杂交幼苗为例 | Kimura, S. | PDF | N/A | Estimating fruit tree growth curves in breeding field using fragmented longitudinal data: An application to citrus hybrid seedlings | | 针对可溶性和多通道膜蛋白的表位特异性抗体的从头设计，具有高特异性、可开发性和功能性 | Nabla Bio, | PDF | N/A | De novo design of epitope-specific antibodies against soluble and multipass membrane proteins with high specificity, developability, and function | | 肿瘤发生中无偏倚共现突变景观 | Li, Y. | PDF | N/A | Unbiased co-occurring mutational landscapes in tumorigenesis | | 解锁精准诊断：整合代谢组学与先进机器学习技术的多模态框架 | Shahnazari, P. | PDF | N/A | Unlocking Precision Diagnostics: A Multimodal Framework Integrating Metabolomics with Advanced Machine Learning Techniques | | 成纤维细胞密度是药物诱发心律失常的风险因素 | Hirose, K. | PDF | N/A | Fibroblast Density is a Risk Factor for Drug-induced Arrhythmias | | 对多切片空间分辨转录组数据分析的聚类方法进行全面比较 | Xiong, C. | PDF | N/A | A comprehensive comparison on clustering methods for multi-slide spatially resolved transcriptomics data analysis | | 使用pyCERR和癌症基因组云进行医学图像分析的人工智能应用 | Apte, A. | PDF | N/A | Artificial Intelligence Apps for Medical Image Analysis using pyCERR and Cancer Genomics Cloud | | RAS-PI3K通路在CAFs中塑造肿瘤ECM的物理化学特性并抑制肿瘤进展 | Cuesta, C. | PDF | N/A | RAS-PI3K Pathway in CAFs Shapes Physicochemical Properties of Tumor ECM and restrains Tumor progression | | 通过新型GATA1/TAL1/鞘磷脂合成酶1（SGMS1）转录轴调控细胞周期。对反白血病策略的启示。 | Raza, Y. | PDF | N/A | Regulation of cell cycle by the novel GATA1/TAL1/Sphingomyelin Synthase 1 (SGMS1) transcriptional axis. Implications for anti-leukemic strategies. | | 基于DNA甲基化的细胞类型去卷积揭示了脑肿瘤微环境中的独特细胞组成 | Liu, F. | PDF | N/A | DNA Methylation-Based Cell Type Deconvolution Reveals the Distinct Cell Composition in Brain Tumor Microenvironment | | 非人灵长类中枢神经系统组织和生物流体中反义寡核苷酸的定量通过拼接-连接PCR检测 | Jepp, T. B. C. | PDF | N/A | Antisense Oligonucleotide Quantification via Splint-Ligation PCR Assay in Non-Human Primate Central Nervous System Tissues and Biofluids | | 表皮细胞动力学通过调控OsZHD1和OsZHD2调节水稻叶枕关节形态发生和叶片角度形成 | Xu, Y. | PDF | N/A | Epidermal Cell Dynamics Regulates Rice Lamina Joint Morphogenesis and Leaf Angle Formation through OsZHD1 and OsZHD2 Regulation | | 光诱导植物中的光敏色素B（Phytochrome B）发生SUMO化修饰，进而招募免疫调节因子NPR1进入核凝聚体中，从而调控植物的免疫反应。 | Ghosh, S. | PDF | N/A | Light induces Phytochrome B SUMOylation to recruit the immune regulator NPR1 in nuclear condensates to control immunity in plants | | 以下是这段英文的中文翻译：

栽培草莓季节性开花基因型中花启动早期步骤的分子机制

翻译说明： - "Molecular mechanisms" 翻译为“分子机制”。 - "underlying" 表示“基础的”或“内在的”，这里翻译为“的”。 - "early steps" 翻译为“早期步骤”。 - "floral initiation" 翻译为“花启动”或“花形成”。 - "seasonal flowering genotypes" 翻译为“季节性开花基因型”。 - "cultivated strawberry" 翻译为“栽培草莓”。

希望这个翻译对你有帮助！如果需要进一步调整或解释，请告诉我。 | Ziegler, F. M. R. | PDF | N/A | Molecular mechanisms underlying the early steps of floral initiation in seasonal flowering genotypes of cultivated strawberry | | Rubisco在整个生命树中都是缓慢的。 | de Pins, B. | PDF | N/A | Rubisco is slow across the tree of life | | 基因编辑的低免疫原性人原代胆管细胞类器官的免疫和突变特征 | Petrus-Reurer, S. | PDF | N/A | Immune and Mutational Profile of Gene-Edited Low-Immunogenic Human Primary Cholangiocyte Organoids | | CAR T细胞工程影响抗原非依赖性激活和共抑制 | Stuecheli, S. | PDF | N/A | CAR T cell engineering impacts antigen-independent activation and co-inhibition | | Scube2通过招募高密度脂蛋白（HDL）受体到质膜上，启动Dispatched和ADAM10介导的Shh（Sonic Hedgehog）释放。 | Puschmann, J. | PDF | N/A | Scube2 primes Dispatched and ADAM10-mediated Shh release by recruiting HDL acceptors to the plasma membrane | | 含Valosin蛋白是淀粉样前体蛋白细胞外囊泡中的货物 | Lue, Y. | PDF | N/A | Valosin-containing Protein is Cargo in Amyloid Precursor Protein Extracellular Vesicles | | 选择由不同细胞外基质分子驱动的白血病前期造血干细胞 | Jassinskaja, M. | PDF | N/A | Selection of pre-leukemic hematopoietic stem cells driven by distinct extracellular matrix molecules | | LIN28介导的基因调控环路同步器官发生过程中的发育转变 | Thevarajan, I. | PDF | N/A | LIN28-mediated gene regulatory loops synchronize developmental transitions throughout organogenesis | | 人类生长的二元细胞生物学 II 从胎儿各部分大小计算人类胎儿的大小 | Gu, Z. | PDF | N/A | The Binary Cellular Biology of Human Growth II Calculating the Size of the Human Fetus from the Size of its Parts | | 早期人类大脑发育中专一性tRNA表达的鉴定 | Bagi, A. L. | PDF | N/A | Identification of Specialized tRNA Expression in Early Human Brain Development | | 在肝脏发育过程中，通过胶原蛋白I进行的机械信号传导调节胆管细胞的定向分化和小管形成。 | Thelwall, I. G. | PDF | N/A | Mechanical signalling through collagen I regulates cholangiocyte specification and tubulogenesis during liver development | | 2019-2022年法国北部狍子（Capreolus capreolus）中针对伯氏疏螺旋体和蜱传脑炎病毒的血清学空间分布模式 | Metras, R. | PDF | N/A | Spatial pattern of serology against Borrelia and tick-borne encephalitis virus in roe deer (Capreolus capreolus), Northern France, 2019-2022 | | 与阿拉伯按蚊相比，疟疾媒介非洲按蚊的延迟交配和交配行为 | Hape, E. E. | PDF | N/A | Delayed copulation and mating in the malaria vector Anopheles funestus compared to Anopheles arabiensis | | 以下是这段英文的中文翻译：

"微孢子虫系统发育中基因组结构和表观遗传修饰的变异"

翻译解释： - "Variation" 翻译为 "变异" - "genome architecture" 翻译为 "基因组结构" - "epigenetic modification" 翻译为 "表观遗传修饰" - "across the microsporidia phylogeny" 翻译为 "微孢子虫系统发育中"

注：上述翻译基于提供的信息，假设“Distinct Genetic Populations and Resistance Backgrounds”指的是对法氏按蚊在坦桑尼亚地区不同遗传种群及其抗药性背景的研究。如果上下文有更具体的指向，翻译可相应调整。 | Odero, J. O. | PDF | N/A | Distinct Genetic Populations and Resistance Backgrounds of the Malaria Vector Anopheles funestus in Tanzania | | 大量分离分析揭示了与科罗拉多马铃薯甲虫对吡虫啉抗性相关的基因组区域。 | Edison, A. | PDF | N/A | Bulk segregant analysis reveals genomic regions associated with imidacloprid resistance in the Colorado potato beetle | | 在为期两年的新生儿和儿童血流感染调查中，马拉色菌（Malassezia furfur）分离株的遗传多样性有限，这证实了在深部感染中存在对一种特定IGS1基因型的偏好。 | Theelen, B. | PDF | N/A | Limited genetic diversity among Malassezia furfur isolates during two one-year neonatal and pediatric bloodstream infection surveys confirms preference for one specific IGS1 genotype in deep-seated infections | | DNA呼吸对转录因子物理相互作用的贡献 | Butt, W. A. | PDF | N/A | Contribution of DNA breathing to physical interactions with transcription factors | | 鉴定两种难以捉摸的人类核糖核酸酶MRP特异性蛋白成分 | Che, R. | PDF | N/A | Identification of Two Elusive Human Ribonuclease MRP-Specific Protein Components | | 使用语言模型预测CRISPR碱基编辑器在组织特异性转录组中RNA脱靶风险 | Nakamae, K. | PDF | N/A | Risk Prediction of RNA Off-Targets of CRISPR Base Editors in Tissue-Specific Transcriptomes Using Language Models | | 识别驱动细胞分化的转录因子 | Martini, P. | PDF | N/A | Identifying transcription factors driving cell differentiation | | PDP-Miner：一种人工智能/机器学习工具，用于在数千个细菌基因组中检测具有解聚酶结构域的噬菌体尾部蛋白 | Gauthier, J. | PDF | N/A | PDP-Miner: an AI/ML tool to detect prophage tail proteins with depolymerase domains across thousands of bacterial genomes | | 对留尼汪岛CHIKGene队列中慢性基孔肯雅热的转录组分析揭示了感染后10多年基因表达的变化 | Gerardin, P. | PDF | N/A | Transcriptomic analysis of chronic chikungunya in the Reunionese CHIKGene cohort uncovers a shift in gene expression more than 10 years after infection | | 利用深度学习驱动的优化和分子模拟挖掘内源性肽组中的肽结合物 | Hartman, E. | PDF | N/A | Mining the endogenous peptidome for peptide binders with deep learning-driven optimization and molecular simulations | | 大规模人群研究中的人类微生物组研究的全面质量控制流程 | Li, R. | PDF | N/A | A comprehensive quality control pipeline in human microbiome research for large population studies | | 整合多层工作流程用于翻译后修饰的定量分析 | Devesa, C. A. | PDF | N/A | Integrative multi-layer workflow for quantitative analysis of post-translational modifications | | SGLT2抑制剂的脱靶效应预测：一种揭示结构机制的综合生物信息学方法 | Yang, H.-J. | PDF | N/A | Off-target prediction of SGLT2 inhibitors: an integrative bioinformatics approach to uncover structural mechanisms | | 在中枢和周围神经系统肿瘤中，PLK1与EYA家族抑制剂之间存在强大的合成致死效应。 | Nelson, C. B. | PDF | N/A | Potent synthetic lethality between PLK1 and EYA-family inhibitors in tumours of the central and peripheral nervous system | | araCNA：利用长程序列模型进行体细胞拷贝数分析 | Visscher, E. | PDF | N/A | araCNA: Somatic copy number profiling using long-range sequence models | | 外骨膜素第17外显子跳跃增强了局部AAV-微肌营养不良蛋白给药在杜氏肌营养不良纤维化模型中的疗效 | Trundle, J. | PDF | N/A | Periostin exon 17 skipping enhances the efficacy of local AAV-microdystrophin administration in a fibrotic model of Duchenne muscular dystrophy | | 《骨间膜智能特性基础的弹性蛋白与胶原蛋白分布》

这段翻译为中文是：《骨间膜智能特性基础的弹性蛋白与胶原蛋白分布》。这个标题指的是一项研究或文章，探讨了在骨间膜（interosseous membrane）中弹性蛋白（elastin）和胶原蛋白（collagen）的分布情况，这些蛋白质的分布被认为是骨间膜具有某些“智能”或特殊功能特性的基础。 | Anastopolous, S. | PDF | N/A | The Distribution of Elastin and Collagen Underpinning the Smart Properties of the Interosseous Membrane | | 脂联素在热量限制期间对脂质、氨基酸和葡萄糖代谢产生性别依赖性的影响。 | Ikushima, Y. M. | PDF | N/A | Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction | | Tobamovirus抗性基因Tm-1对番茄ToBRFV抗性控制的贡献 | Zinger, A. | PDF | N/A | Contribution of the Tobamovirus resistance gene Tm-1 to control of ToBRFV resistance in tomato | | 一个强大的平台，用于简化芳香族非天然氨基酸的生物合成和大肠杆菌中的遗传密码扩展。 | Zhang, J. | PDF | N/A | A robust platform streamlining aromatic noncanonical amino acid biosynthesis and genetic code expansion in E. coli | | 细胞图谱与表型的发育基础 | Lou, A. | PDF | N/A | Cell atlases and the Developmental Foundations of the Phenotype | | Mef2c通过调节对Ephrin排斥的敏感性来控制出生后胼胝体轴突的靶向 | Sudarsanam, S. | PDF | N/A | Mef2c Controls Postnatal Callosal Axon Targeting by Regulating Sensitivity to Ephrin Repulsion | | 感觉运动适应揭示了三维感知中的系统性偏差。 | Lim, C. | PDF | N/A | Sensorimotor adaptation reveals systematic biases in 3D perception. | | 大型动物癫痫模型平台：海马区颞叶癫痫的卡因酸猪模型 | Mivalt, F. | PDF | N/A | Large Animal Epilepsy Model Platform: Kainic Acid Porcine Model of Mesial Temporal Lobe Epilepsy | | CLASP1/2 调节自然杀伤细胞中免疫突触的成熟 | Pariani, A. P. | PDF | N/A | CLASP1/2 REGULATE IMMUNE SYNAPSE MATURATION IN NATURAL KILLER CELLS | | SLAMF6能够促进病毒特异性CD8+ T细胞高效附着、形成突触并杀死HIV-1感染的CD4+ T细胞。 | Monel, B. | PDF | N/A | SLAMF6 enables efficient attachment, synapse formation, and killing of HIV-1-infected CD4+ T cells by virus-specific CD8+ T cells | | 类风湿性关节炎免疫突触中的STAT3磷酸化 | Novak, H. | PDF | N/A | STAT3 phosphorylation in the rheumatoid arthritis immunological synapse | | SwiftMHC：一种用于MHC结合肽识别和3D建模的高速注意力网络 | Xue, L. C. | PDF | N/A | SwiftMHC: A High-Speed Attention Network for MHC-Bound Peptide Identification and 3D Modeling | | 坏死碎片的降解而非分解对于促进急性肝损伤后的恢复至关重要。 | Schuermans, S. | PDF | N/A | Degradation rather than disassembly of necrotic debris is essential to enhance recovery after acute liver injury | | 核苷酸切除修复内切酶XPF在动基体寄生虫布氏锥虫中的作用 | Gomez-Linan, C. | PDF | N/A | Role of the Nucleotide Excision Repair endonuclease XPF in the kinetoplastid parasite Trypanosoma brucei | | 硫代奎诺糖在小鼠和人类肠道微生物群中的降解方式不同，且不会被宿主代谢。 | Krasenbrink, J. | PDF | N/A | Sulfoquinovose is differently degraded by the mouse and human gut microbiota and not metabolized by the host | | I型分区相关蛋白通过转录激活和oriT区域结合增强接合转移 | Kishida, K. | PDF | N/A | Type I partition-related proteins enhance conjugative transfer through transcriptional activation and oriT region binding | | 细胞外聚合物降解塑造了微生物群落的多样性 | Pontrelli, S. | PDF | N/A | Extracellular polymeric substance degradation shapes microbial community diversity | | 西尼罗河病毒基因组中CpG和UpA二核苷酸增加对库蚊传播病毒及脊椎动物宿主发病机制的影响 | van Bree, J. | PDF | N/A | The effect of increased CpG and UpA dinucleotides in the West Nile virus genome on virus transmission by Culex mosquitoes and pathogenesis in a vertebrate host | | 在鲍曼不动杆菌中，针对抗菌肽TAT-RasGAP317-326的体外耐药性筛选可通过pmrAB基因的突变导致对多粘菌素的交叉耐药性。 | Ritz, E. | PDF | N/A | In vitro resistance selection in Acinetobacter baumannii against the antimicrobial peptide TAT-RasGAP317-326 can cause cross-resistance to polymyxins through mutations in pmrAB | | ca-circSCN8A通过LLPS引发的R-Loop促进HPASMCs的铁死亡 | Li, M. | PDF | N/A | ca-circSCN8A promotes HPASMCs ferroptosis via LLPS initiated R-Loop | | 全球范围内N端半胱氨酸依赖性降解机制的剖析 | Bekturova, A. | PDF | N/A | Global Profiling of N-terminal Cysteine-Dependent Degradation Mechanisms | | 灵长类特有的微小RNA-1202通过靶向APC2调控多巴胺能神经元的生成，并在中脑类器官中调节WNT/β-catenin信号通路。 | Long, X. | PDF | N/A | Primate-specific microRNA-1202 regulates dopaminergic neurogenesis by targeting APC2 and modulates WNT/β-catenin signaling pathway in midbrain organoid | | 以下是这段文字的中文翻译：

两种马达加斯加果蝠（杜氏果蝠 Eidolon dupreanum 和马达加斯加狐蝠 Rousettus madagascariensis）体外寄生虫负担的多样性和季节性研究。

翻译说明： 1. "Diversity and seasonality" 翻译为“多样性和季节性”。 2. "ectoparasite burden" 翻译为“体外寄生虫负担”，指寄生在宿主体表的寄生虫数量或影响。 3. "two species of Madagascar fruit bat" 翻译为“两种马达加斯加果蝠”，具体指后文提到的两种蝙蝠。 4. "Eidolon dupreanum" 和 "Rousettus madagascariensis" 分别是两种蝙蝠的学名，翻译时保留拉丁学名，同时补充中文名“杜氏果蝠”和“马达加斯加狐蝠”。

希望这个翻译对你有帮助！ | Andrianiaina, A. F. | PDF | N/A | Diversity and seasonality of ectoparasite burden on two species of Madagascar fruit bat, Eidolon dupreanum and Rousettus madagascariensis | | 稀有真菌类群的空间周转率较低，主要由草地土壤中的随机过程主导。 | Zhang, B. | PDF | N/A | Lower spatial turnover of rare fungal taxa dominantly shaped by stochastic processes in grassland soils | | 在绘制濒危地中海僧海豹分布图时，社交媒体和新闻媒体的作用：数据获取的显著提升与持续存在的偏见 | Castro, A. | PDF | N/A | Social and news media in mapping the endangered Mediterranean Monk seal: exceptional data gains but persistent bias | | 法罗群岛巨型小鼠的群体基因组学：杂交、殖民化以及对识别选择基因组目标的新挑战 | Payseur, B. A. | PDF | N/A | Population Genomics of Giant Mice from the Faroe Islands: Hybridization, Colonization, and a Novel Challenge to Identifying Genomic Targets of Selection | | 球茎大麦（Hordeum bulbosum；禾本科）的区域解析系统地理学 | Blattner, F. R. | PDF | N/A | An area-resolved phylogeography of bulbous barley (Hordeum bulbosum; Poaceae) | | 生物信息学分析揭示了Trefoil因子3参与哮喘发病机制的分子机制 | He, F. | PDF | N/A | Bioinformatic analysis reveals the molecular mechanisms of Trefoil factor 3 involved in asthma pathogenesis | | 在陨石衍生的培养物中发现单链DNA：新型遗传元素的证据。 | Lopez Ramon y Cajal, C. | PDF | N/A | Discovery of single-stranded DNA in meteorite-derived cultures: evidence of novel genetic elements. | | 计算设计的干细胞表位模拟物能够引发广泛反应的抗体。 | Wehrle, S. | PDF | N/A | Computationally designed stem-epitope mimetics elicit broadly reactive antibodies | | 这段文字翻译成中文是：一种无半胱氨酸且超快速的分裂内含肽，通过理性设计从易聚集转变为在蛋白质反式剪接中高效。 | Humberg, C. | PDF | N/A | A Cysteine-Less and Ultra-Fast Split Intein Rationally Engineered from Being Aggregation-Prone to Highly Efficient in Protein trans-Splicing | | 通过非经典氨基酸诱变技术研究α-突触核蛋白中所有与疾病相关的赖氨酸乙酰化位点 | Shimogawa, M. | PDF | N/A | Investigation of All Disease-Relevant Lysine Acetylation Sites in α-Synuclein Enabled by Non-canonical Amino Acid Mutagenesis | | BRCA1-BARD1复合物BRCT重复序列识别磷酸化RNAPII C端结构域的不同机制：来自结构和功能分析的见解 | Klapstova, V. | PDF | N/A | Distinct Mechanisms of Recognition of Phosphorylated RNAPII C-Terminal Domain by BRCT Repeats of the BRCA1-BARD1 Complex: Insights from Structural and Functional Analyses | | 虚弱代谢组学生物标志物：一项关于雌性和雄性小鼠衰老的纵向研究 | Zhu, D. | PDF | N/A | Metabolomics biomarkers of frailty: a longitudinal study of aging female and male mice | | 通过计算方法从Cochlospermum物种中分离的生物活性化合物发现新型HMG-CoA还原酶抑制剂 | Olatoye, T. I. | PDF | N/A | Discovery of Novel Inhibitors of HMG-CoA Reductase using Bioactive Compounds isolated from Cochlospermum Species through Computational Methods | | 基于差异表达统计证据的基因排序贝叶斯框架 | Hoerbst, F. | PDF | N/A | A Bayesian framework for ranking genes based on their statistical evidence for differential expression | | RNA-seq基因融合检测工具的荟萃分析：在基准测试中的性能和变异性 | Ostrowska, I. | PDF | N/A | Meta-analysis of RNA-seq gene fusion detection tools: performance and variability across benchmarks | | 以下是将这段英文翻译成中文的结果：

全光学策略以最小化可逆切换荧光蛋白的光漂白

翻译解释： - All-Optical Strategies：全光学策略，指的是完全基于光学手段的方法或技术。 - Minimize：最小化，意味着减少或降低到最低程度。 - Photo-Bleaching：光漂白，指的是在光照条件下，荧光分子失去其荧光特性的现象。 - Reversibly Switchable Fluorescent Proteins：可逆切换荧光蛋白，指的是能够通过某种刺激（如光、化学物质等）在荧光和非荧光状态之间可逆切换的荧光蛋白。

热响应性动态变化在珊瑚Acropora cervicornis的选择性剪接中 | Stankiewicz, K. H. | PDF | N/A | Heat-responsive dynamic shifts in alternative splicing of the coral Acropora cervicornis | | 肺免疫细胞群体中的单细胞转录组特征揭示结节病的标志 | Moore, C. | PDF | N/A | Single Cell Transcriptome Signatures of Sarcoidosis in Lung Immune Cell Populations | | 真菌感染和治疗期间，Galleria mellonella 幼虫转录起始位点的全基因组定位 | Abugessaisa, I. | PDF | N/A | Genome-wide mapping of the Galleria mellonella larvae transcription start sites during fungal infection and treatment | | 冷冻电镜与分子动力学模拟揭示未成熟登革热病毒样颗粒的结构特征 | Palur, V. R. | PDF | N/A | Structural Insights into Immature Dengue Virus-Like Particles Revealed by Cryo-EM and Molecular Dynamics Simulations | | 在高膨胀压力下的大肠杆菌细胞壁的非线性连续介质描述 | Albarran, O. | PDF | N/A | Nonlinear continuum description of the E. coli cell wall under high turgor pressure | | 亚基旋转如何控制核糖体中tRNA的动态 | Byju, S. | PDF | N/A | How subunit rotation controls tRNA dynamics in the ribosome | | 多种正黄病毒在蚊子唾液中分泌sfRNA，通过抑制MDA5介导的早期干扰素反应来促进传播。 | Serrato-Pomar, I. | PDF | N/A | Multiple orthoflaviviruses secrete sfRNA in mosquito saliva to promote transmission by inhibiting MDA5-mediated early interferon response | | 组蛋白甲基转移酶DOT1L维持CD8 T细胞的身份并限制其细胞毒性潜能 | Malik, M. | PDF | N/A | Histone methyltransferase DOT1L maintains identity and restricts cytotoxic potential of CD8 T cells | | RNA结合蛋白RSRC2通过与长链非编码RNA C1QTNF1-AS1相互作用，促进有丝分裂的准确性。 | Georgieva, K. | PDF | N/A | The RNA-binding protein RSRC2 promotes mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1 | | 染色体乘客复合体识别核小体的枢轴-系链模型 | Ruza, R. R. | PDF | N/A | A pivot-tether model for nucleosome recognition by the chromosomal passenger complex | | 抑制由Cullin-3适配蛋白SHKBP1介导的SQSTM1/p62寡聚化和Keap1隔离 | Luan, L. | PDF | N/A | Inhibition of SQSTM1/p62 oligomerization and Keap1 sequestration by the Cullin-3 adaptor SHKBP1 | | 工具使用的大脑表征与执行动作的身体部位和运动经验无关 | Martinez-Addiego, F. | PDF | N/A | Tool-use brain representations are independent of the acting body part and motor experience | | 转座子入侵灵长类基因组塑造了人类炎症增强子及炎症疾病易感性 | Ye, M. | PDF | N/A | Transposon invasion of primate genomes shaped human inflammatory enhancers and susceptibility to inflammatory diseases | | 贝叶斯数据驱动的动粒动力学建模：人类中期板的时空组织 | Koki, C. | PDF | N/A | Bayesian data driven modelling of kinetochore dynamics: space-time organisation of the human metaphase plate |

BioRxiv 2025-01-21 Papers

标题	作者	PDF链接	代码仓库	Title
解开具有多种中间神经元类别的皮质回路中的稳定性和增益调节	Bos, H.	PDF	N/A	Untangling stability and gain modulation in cortical circuits with multiple interneuron classes
深入剖析癌症蛋白质组，从标准RNA制备试剂盒的流穿液中获取，用于精准肿瘤学	Mundt Madsen, F.	PDF	N/A	In depth profiling of the cancer proteome from the flowthrough of standard RNA-preparation kits for precision oncology
研究年龄和听力损失对语音清晰度和振幅调制频率选择性的影响	Regev, J.	PDF	N/A	Investigating the effects of age and hearing loss on speech intelligibility and amplitude modulation frequency selectivity
“暗分类学”：一种新协议，旨在克服暗分类群的分类障碍并扩大生物多样性评估的分类群基础	Meier, R.	PDF	N/A	"Dark taxonomy": a new protocol for overcoming the taxonomic impediments for dark taxa and broadening the taxon base for biodiversity assessment
对新加坡（面积730平方公里）的蕈蚊科（双翅目：毛蚊总科）进行综合分类研究，揭示了115个新物种。	Amorim, D. d. S.	PDF	N/A	An integrative taxonomic treatment of the Mycetophilidae (Diptera: Bibionomorpha) from Singapore reveals 115 new species on 730km2
过量的新生儿睾酮会导致野生型小鼠出现雄性特有的社交和恐惧记忆缺陷。	Quinones-Labernik, P.	PDF	N/A	Excess neonatal testosterone causes male-specific social and fear memory deficits in wild-type mice
基于光泵磁力计的脑磁图技术向人类早期生命研究的边界推进	Corvilain, P.	PDF	N/A	Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life
集体定向记忆控制上皮细胞迁移的范围	Canever, H.	PDF	N/A	Collective directional memory controls the range of epithelial cell migration
揭示P450还原酶在除草剂代谢抗性机制中的作用	Rigon, C. A. G.	PDF	N/A	Unraveling the Role of P450 Reductase in Herbicide Metabolic Resistance Mechanism
额叶皮层中精神努力的神经代谢预测因素	Barakat, A.	PDF	N/A	Neurometabolic predictors of mental effort in the frontal cortex
上皮细胞中的趋同基因表达揭示了子宫容受性的进化	Brulport, A.	PDF	N/A	Convergent gene expression in epithelial cells illuminates the evolution of uterine receptivity
脊髓损伤中星形胶质细胞向神经元重编程的挑战与效能：体外研究见解与体内结果	NICEFORO, A.	PDF	N/A	Challenges and Efficacy of Astrocyte-to-Neuron Reprogramming in Spinal Cord Injury: In Vitro Insights and In Vivo Outcomes
人类遗传变异rs6190揭示了Foxc1和Arid5a作为糖皮质激素受体在肌肉中的新型促代谢靶点。	Prabakaran, A. D.	PDF	N/A	The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle.
转录组范围内通过脱氨酶和阅读蛋白辅助测序鉴定5-甲基胞嘧啶	Zhou, J.	PDF	N/A	Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing
以下是这段英文的中文翻译：

稳健、高通量且时间可调控的roxCre和loxCre报告系统用于体内基因修饰

翻译解释： - robust：稳健的，指系统稳定可靠。 - high-throughput：高通量的，指系统能够处理大量样本或数据。 - temporally regulated：时间可调控的，指系统能够根据时间进行精确调控。 - roxCre and loxCre reporting systems：roxCre和loxCre报告系统，这是两种常用于基因编辑的工具。 - genetic modifications in vivo：体内基因修饰，指在活体生物体内进行的基因编辑操作。

希望这个翻译对你有帮助！ | Shi, M. | PDF | N/A | The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo | | TRPg通过Dh44神经内分泌细胞调节脂质代谢。 | Nath, D. K. | PDF | N/A | TRPg regulates lipid metabolism through Dh44 neuroendocrine cells | | 评估使用诱捕法在串联质谱分析中的假发现率控制 | Wen, B. | PDF | N/A | Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment | | 噬菌体组从肠道向循环系统的转移及其受人类免疫系统的调控 | Szymczak, A. | PDF | N/A | Phageome transfer from gut to circulation and its regulation by human immunity | | 青少年期酒精暴露促进机械性异常疼痛并改变从基底外侧杏仁核到前额叶皮层前肢区的突触功能 | Obray, J. D. | PDF | N/A | Adolescent Alcohol Exposure Promotes Mechanical Allodynia and Alters Synaptic Function at Inputs from the Basolateral Amgydala to the Prelimbic Cortex | | 可微分的Gillespie算法用于模拟化学动力学、参数估计以及设计合成生物电路 | Rijal, K. | PDF | N/A | A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits | | Rep结构由开放和闭合状态之间的亚稳态中间体组成，这些中间体的过渡动力学受离子环境的调节。 | Howard, J. A. L. | PDF | N/A | Rep structures comprise metastable intermediates between open and closed states whose transitional kinetics are tuned by the ionic environment | | 为巴甫洛夫关联的学习和消退而存在的空间组织化纹状体广泛乙酰胆碱动态变化 | Bouabid, S. | PDF | N/A | Distinct spatially organized striatum-wide acetylcholine dynamics for the learning and extinction of Pavlovian associations | | 《细胞色素c的折叠与稳定性全面指南及其对疾病的影响》 | Yousaf, M. A. | PDF | N/A | A comprehensive guide through the fold and stability of cytochrome c with implications for disease | | 通过基于组装的策略适应原始读数和蛋白质，实现系统发育关系的可靠推断 | Li, Y. | PDF | N/A | Reliable inference of phylogenomic relationship via assembly-based strategy accommodating raw reads and proteins | | 使用沉积古DNA数据检测生态相互作用的挑战 | Callahan, F. M. | PDF | N/A | Challenges in detecting ecological interactions using sedimentary ancient DNA data | | 重新思考大规模系统基因组学：使用EukPhylo v1.0，一个灵活的工具包，以实现系统发育信息指导的数据管理和多样化真核生物谱系的分析 | Katz, L. A. | PDF | N/A | Rethinking large scale phylogenomics with EukPhylo v1.0, a flexible toolkit to enable phylogeny-informed data curation and analyses of diverse eukaryotic lineages | | 行为差异鹿鼠下丘脑视前区的细胞进化 | Chen, J. | PDF | N/A | Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice | | 描述一种新型极端嗜好绿色藻类——太平洋衣藻（Chlamydomonas pacifica），及其作为生物技术宿主的潜力 | Dutra Molino, J. V. | PDF | N/A | Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host | | 早期发育及脑微结构与功能连接组的共演化：一项针对早产儿和足月儿的多模态MRI研究 | Gondova, A. | PDF | N/A | Early development and co-evolution of microstructural and functional brain connectomes: A multi-modal MRI study in preterm and full-term infants | | 使用对比学习进行遗传数据的降维 | Thor, F. | PDF | N/A | Dimensionality Reduction of Genetic Data using Contrastive Learning | | 探索顺式作用基因调控的极限：基于等位基因失衡数量性状位点的模型研究 | Seoighe, C. | PDF | N/A | Probing the limits of cis-acting gene regulation using a model of allelic imbalance quantitative trait loci | | 提高分子字符串表示在生成化学中的可靠性 | Reboul, E. | PDF | N/A | Improving the reliability of molecular string representations for generative chemistry | | 理解神经元多样性：输入动态与滤波的作用 | Joshi, N. | PDF | N/A | Understanding Neuronal Diversity: Role of Input Dynamics and Filtering | | 计算识别空间转录组数据中的迁移T细胞 | Zhong, L. | PDF | N/A | Computational Identification of Migrating T cells in Spatial Transcriptomics Data | | 在时间变化的环境中，优势逆转维持了大效应抗性多态性。 | Karageorgi, M. | PDF | N/A | Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments | | 克服艰难梭菌分型中的重复性和变异性挑战 | Bravo-Anton, L. | PDF | N/A | Overcoming challenges of reproducibility and variability for the Clostridioides difficile typification | | 纳米生理学方法揭示斑马鱼视网膜双极带状突触间钙微域的多样性 | Rameshkumar, N. | PDF | N/A | Nanophysiology Approach Reveals Diversity in Calcium Microdomains across Zebrafish Retinal Bipolar Ribbon Synapses | | 脂多糖（LPS）和志贺毒素暴露对培养的人脐静脉内皮细胞RNA表达程序的协同作用。 | Svilar, D. | PDF | N/A | Synergy of LPS and Shiga-toxin exposure on the RNA expression program of cultured human umbilical vein endothelial cells. | | 以下是这段英文的中文翻译：

临床相关伯克霍尔德菌属β-内酰胺酶的动态差异

翻译说明： - "Dynamic Differences" 翻译为“动态差异”。 - "Clinically relevant" 翻译为“临床相关的”。 - "Pen β-Lactamases" 翻译为“β-内酰胺酶”。 - "Burkholderia spp." 翻译为“伯克霍尔德菌属”。

希望这对你有帮助！如果有其他问题，请随时告诉我。 | Gu, J. | PDF | N/A | Dynamic Differences in Clinically relevant Pen β-Lactamases from Burkholderia spp. | | 将深度学习应用于视频分析作为测量家禽中大肠杆菌感染的工具 | Scheidwasser, N. | PDF | N/A | Deep learning from videography as a tool for measuring E. coli infection in poultry | | 在年轻健康成年人中，观察协调动作和进行适应性单腿坐站运动的运动想象时，皮质脊髓兴奋性得到增强。 | Valappil, A. C. | PDF | N/A | Corticospinal excitability is facilitated during coordinative action observation and motor imagery of adapted single-leg sit-to-stand movements in young healthy adults | | 在存在未知个体的情况下对单个动物的声学识别 | Huang, L. | PDF | N/A | Acoustic Recognition of Individual Animals in thePresence of Unknown Individuals | | SAR11菌株的栖息地特异性与少数受到高度选择的基因相关。 | Tucker, S. J. | PDF | N/A | Habitat-specificity in SAR11 is associated with a handful of genes under high selection | | 化学位移和弛豫正则化提高了1H磁共振波谱分析的准确性。 | Wilson, M. | PDF | N/A | Chemical shift and relaxation regularisation improve the accuracy of 1H MR spectroscopy analysis | | 古代基因簇启动单萜吲哚生物碱的生物合成及C3立体化学反转 | Hwang, J. | PDF | N/A | Ancient gene clusters initiate monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion | | 手动与自动注释转座子元素的比较：以果蝇（Drosophila melanogaster）和白纹伊蚊（Aedes albopictus）为例，平衡准确性与生物学相关性 | Carrasco-Valenzuela, T. | PDF | N/A | Manual versus automatic annotation of transposable elements: case studies in Drosophila melanogaster and Aedes albopictus, balancing accuracy and biological relevance | | 在急性环境挑战下斑马鱼尾部神经分泌系统中激素基因表达的变化 | Bichon, B. | PDF | N/A | Hormone gene expression changes in the zebrafish caudal neurosecretory system under acute environmental challenges | | 《Streptocarpus sect. Saintpaulia（非洲紫罗兰）中不稳定的花青素着色现象源于单一MYB基因的转录选择性》 | Kurata, D. | PDF | N/A | Unstable anthocyanin pigmentation in Streptocarpus sect. Saintpaulia (African violet) is due to transcriptional selectivity of a single MYB gene | | Oncodrive3D：快速准确地检测正选择下的体细胞突变结构簇 | Pellegrini, S. | PDF | N/A | Oncodrive3D: Fast and accurate detection of structural clusters of somatic mutations under positive selection | | 在噬菌体诱导过程中，Cro2和CI2与OR操作子结合在控制溶原稳定性中的作用 | Pang, Y. | PDF | N/A | Roles of Cro2 and CI2 binding to OR operators in controlling lysogeny stability during prophage induction | | 甲氨蝶呤治疗下类风湿性关节炎的时间分辨免疫动态 | Preglej, T. | PDF | N/A | Time-resolved immune dynamics in rheumatoid arthritis under Methotrexate therapy | | Wnt信号活性与Sox2转录因子水平的比率预测了神经中胚层命运潜能。 | Morabito, R. D. | PDF | N/A | The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential | | 将系统性硬化症中的空间分辨转录组进行映射 | Li, Z. | PDF | N/A | Mapping spatially-resolved transcriptomes in systemic sclerosis | | CARDBiomedBench：评估大型语言模型在生物医学研究中表现的基准 | Bianchi, O. | PDF | N/A | CARDBiomedBench: A Benchmark for Evaluating Large Language Model Performance in Biomedical Research | | 组蛋白去乙酰化酶-1是粗糙脉孢菌表观基因组稳定所必需的 | Ebot-Ojong, F. | PDF | N/A | Histone deacetylase-1 is required for epigenome stability in Neurospora crassa | | hmde: 微分方程的分层方法 | O'Brien, T. A. | PDF | N/A | hmde: Hierarchical Methods for Differential Equations | | AuthormetriX：从Scopus语料库中自动计算个体作者的非通胀性信用分配方案和合作指标 | Adeosun, S. O. | PDF | N/A | AuthormetriX: Automated Calculation of Individual Authors' Non-Inflationary Credit-Allocation Schemas' and Collaboration Metrics from a Scopus Corpus | | H3K4甲基化促进的转录记忆确保了合子基因组的忠实激活和胚胎发育 | Oak, M. S. | PDF | N/A | H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development | | 一种用于整合蛋白质功能多模态数据的对抗性方案 | Nasser, R. | PDF | N/A | An adversarial scheme for integrating multi-modal data on protein function | | AI驱动的发现：宿主硫氧还蛋白作为CRISPR增强剂，促进噬菌体编码的微型Cas12黑客核酸酶的功能 | Wang, Z. | PDF | N/A | AI-driven discovery of host thioredoxin as a CRISPR enhancer of phage-encoded miniature Cas12 hacker nuclease | | 假定的肺炎克雷伯菌生态梯度 | Liu, S. | PDF | N/A | A putative ecocline in Klebsiella pneumoniae | | 产后人类内颅和大脑结构中大小与形状的相互作用 | Takagi, K. | PDF | N/A | Postnatal interaction of size and shape in the human endocranium and brain structures | | baal-nf 识别出那些降低转录因子结合亲和力的基序破坏变异。 | Roskams-Hieter, B. | PDF | N/A | baal-nf identifies motif-disrupting variants that decrease transcription factor binding affinity | | 计算设计的靶向RAD51-BRCA2相互作用的适配体抑制RAD51核募集 | Miliordini, G. | PDF | N/A | Computationally-designed aptamers targeting RAD51-BRCA2 interaction inhibit RAD51 nuclear recruitment | | ESMAdam：一种即插即用的通用蛋白质集合生成器 | Yu, Z. | PDF | N/A | ESMAdam: a plug-and-play all-purpose protein ensemble generator | | 底物识别的两个阶段决定了大肠杆菌MetNI-Q ABC转运系统的选择性 | Yang, J. G. | PDF | N/A | Two stages of substrate discrimination dictate selectivity in the E. coli MetNI-Q ABC transporter system | | D类β-内酰胺酶中的标准化残基编号与二级结构命名法 | Stasyuk, A. | PDF | N/A | Standardized Residue Numbering and Secondary Structure Nomenclature in the Class D β-Lactamases | | 多区域脑类器官：融合了大脑、内皮和中后脑组件的融合类器官 | Kshirsagar, A. | PDF | N/A | Multi-Region Brain Organoid: Fusion Organoid with Cerebral, Endothelial and Mid-Hindbrain Components | | 通过HighFold2预测含有非天然氨基酸的环肽结构 | Zhu, C. | PDF | N/A | Predicting the structures of cyclic peptides containing unnatural amino acids by HighFold2 | | 以下是将这段英文翻译成中文的结果：

一个链接基因组学测序和质谱多模态数据集及模型，用于简化微生物菌株库中天然产物的发现。

翻译解释： - Linked Genomics Sequencing and Mass Spectrometry: 链接基因组学测序和质谱 - multi-modal dataset: 多模态数据集 - models: 模型 - Streamlined Natural Products Discovery: 简化的天然产物发现 - Microbial Strain Libraries: 微生物菌株库

深层永久冻土中的微生物复苏与生长速率：阿拉斯加福克斯永久冻土研究隧道的脂质稳定同位素探测结果

翻译说明： - Microbial Resuscitation：微生物复苏，指微生物从休眠状态恢复活性的过程。 - Growth Rates：生长速率，指微生物繁殖或代谢的速度。 - Deep Permafrost：深层永久冻土，指地下较深处的永久冻结层。 - Lipid Stable Isotope Probing：脂质稳定同位素探测，一种用于研究微生物代谢活动的技术。 - Permafrost Research Tunnel：永久冻土研究隧道，位于阿拉斯加福克斯的一个研究设施。

男性和女性参与者在步行足球训练期间的外部与内部负荷概况

这个标题描述了一项研究或分析，旨在探讨男性和女性在步行足球训练中的外部负荷（如运动量、速度、距离等）和内部负荷（如心率、疲劳程度等）的表现和差异。 | da Costa, J. A. H. C. | PDF | N/A | External and Internal Load Profiles of Male and Female Participants during a Walking Football Practice | | 开发一种新型小鼠模型用于研究支架内新生动脉粥样硬化 | Liu, J. | PDF | N/A | Development of a novel murine model of in-stent neoatherosclerosis | | 系统遗传学方法揭示了蛋白酶体因子在心脏发育和先天性心脏缺陷中的作用。 | Farr, G. H. | PDF | N/A | A systems genetics approach identifies roles for proteasome factors in heart development and congenital heart defects | | Seo1p是一种在酵母和真菌中具有高亲和力的γ-谷氨酰甲硫氨酸（gamma-Glu-met）二肽的质膜转运蛋白。 | Dubey, P. | PDF | N/A | Seo1p, a high affinity, plasma membrane transporter of the gamma-Glu-met dipeptide in yeasts and fungi | | 倒位在高度混合的欧洲沙丁鱼（Sardina pilchardus）的进化中占据主导地位 | Sabatino, S. J. | PDF | N/A | Inversions Dominate Evolution in the Highly Admixed European Sardine (Sardina pilchardus) | | 社会许可压力与澳大利亚公众对野犬致命控制的支持。 | Pearson, A. I. | PDF | N/A | Social License Pressure and Public Support for the Lethal Control of Dingoes in Australia. | | OT-Mation：一个开源代码，用于将CSV文件解析为Python脚本，以控制OT-2液体处理机器人。 | Laverick, A. | PDF | N/A | OT-Mation: an open-source code for parsing CSV files into python scripts for control of OT-2 liquid handling robotics | | 炎症小体适配蛋白ASC在肥胖期间引发的菌群失调导致免疫代谢紊乱 | Martinez-Garcia, J. J. | PDF | N/A | The inflammasome adaptor protein ASC triggers immunometabolic dysregulation induced by dysbiosis during obesity | | 优化生物力学性能的线圈增强多层血管移植物的先进制造 | Robinson, A. | PDF | N/A | Advanced Manufacturing of Coil-Reinforced Multilayer Vascular Grafts to Optimize Biomechanical Performance | | Parapipe：处理寄生虫NGS数据集的流程及其在隐孢子虫中的应用 | Morris, A. V. | PDF | N/A | Parapipe: a Pipeline for Handling Parasite NGS Datasets and its Application to Cryptosporidium | | CPI-Pred：一个用于预测化合物-蛋白质相互作用功能参数的深度学习框架 | Xu, Z. | PDF | N/A | CPI-Pred: A deep learning framework for predicting functional parameters of compound-protein interactions | | 通过Householder反射的反射仿制品：在蛋白质组学和遗传精细定位中的应用 | Guan, Y. | PDF | N/A | Reflection Knockoffs via Householder Reflection: Applications in Proteomics and Genetic Fine Mapping | | GLUT5装甲增强了在葡萄糖限制条件下过继性T细胞疗法的抗肿瘤活性。 | Page, R. | PDF | N/A | GLUT5 armouring enhances adoptive T cell therapy anti-tumour activity under glucose-limiting conditions | | 在变化环境中的物种分布范围和生态位的演变 | Polechova, J. | PDF | N/A | Evolution of species' range and niche in changing environments | | 估计强化学习中的运动探索 | Zai, A. T. | PDF | N/A | Estimating the motor exploration in reinforcement learning | | 声音增强的睡眠深度减少创伤性脑损伤的损害和后遗症，并支持小胶质细胞的反应 | Moreira, C. C. G. | PDF | N/A | Sound-Enhanced Sleep Depth Reduces Traumatic Brain Injury Damage and Sequelae and Supports Microglial Response | | 每日间歇性禁食在无癫痫发作的临床前模型中是一种有效的多尺度治疗方法。 | Rulhe, C. | PDF | N/A | Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy | | 鼻至脑的治愈之路：缺氧预处理的间充质干细胞促进缺氧缺血性脑病大鼠的恢复 | Serrenho, I. | PDF | N/A | Nose-to-Brain Healing: Hypoxia-Preconditioned Mesenchymal Stem Cells Prompt Recovery in Hypoxic-Ischemic Encephalopathy Rats | | GAL-101能够防止β淀粉样蛋白在两种不同类型的视网膜细胞中引起的膜电位去极化。 | Pizzi, E. | PDF | N/A | GAL-101 prevents amyloid beta-induced membrane depolarization in two different types of retinal cells | | DNA甲基化作为STX6及其他额颞叶变性遗传风险相关位点失调的贡献者 | Rambarack, N. | PDF | N/A | DNA methylation as a contributor to dysregulation of STX6 and other frontotemporal lobar degeneration genetic risk-associated loci | | 平息风暴：低氧作为增强UC-MSC治疗新生儿缺氧缺血性脑病的策略 | Serrenho, I. | PDF | N/A | Quieting the Storm: Hypoxia as a Strategy to Boost UC-MSC Therapies for Neonatal Hypoxic-Ischemic Encephalopathy | | I型nNOS神经元协调皮质神经活动和血管运动 | Turner, K. | PDF | N/A | Type-I nNOS neurons orchestrate cortical neural activity and vasomotion | | p16.1和p16.2，作为新的造血干细胞和祖细胞（HSPC）标记物，在斑马鱼的T细胞淋巴生成过程中扮演着冗余的角色。 | Gomez, E. | PDF | N/A | p16.1 and p16.2, new HSPC markers, play redundant roles in zebrafish T-cell lymphopoiesis | | 通过Notch对神经前体细胞进行表观遗传学预编程，增强了Sonic hedgehog信号通路，并建立了胶质细胞生成的能力。 | Tran, L. N. | PDF | N/A | Epigenetic priming of neural progenitors by Notch enhances Sonic hedgehog signaling and establishes gliogenic competence | | 输注同种异体小鼠HOD红细胞优先诱导低亲和力、短寿命的IgG抗体，这些抗体的产生不依赖于生发中心。 | Medved, J. | PDF | N/A | Transfusion of allogenic murine HOD red blood cells preferentially induces low-affinity, short-lived IgG antibodies that are germinal center independent | | I型干扰素-IL-27轴促进mRNA疫苗诱导的CD8+ T细胞反应 | Phan, A. T. | PDF | N/A | The type I IFN-IL-27 axis promotes mRNA vaccine-induced CD8+ T cell responses | | 使用景观生物多样性指标评估再野化：以克内普庄园与布斯比荒野农业基线进行时空对比 | Pates, N. J. | PDF | N/A | Using landscape biodiversity metrics to assess rewilding: a space-for-time comparison between the Knepp Estate and an agricultural baseline at Boothby Wildland | | 难以采样的物种对土地利用变化更为敏感：对全球生物多样性指标的影响 | Gutierrez-Arellano, C. | PDF | N/A | Hard-to-sample species are more sensitive to land-use change: implications for global biodiversity metrics | | 解码瓢虫的颜色：颜色产生的结构机制与色素调控。 | CARRADA, M. | PDF | N/A | Decoding ladybird's colours: structural mechanisms of colour production and pigment modulation. | | 胆碱能动态在海马隔系统中为空间新颖性提供了阶段性多路复用信号，并与行为状态相关。 | Moghadam, F. F. | PDF | N/A | Cholinergic dynamics in the septo-hippocampal system provide phasic multiplexed signals for spatial novelty and correlate with behavioral states | | 常规核小体与CENP-A核小体在溶液中的构象差异，在高压下的可逆变形作用下更加显著。 | Gupta, K. | PDF | N/A | Solution conformational differences between conventional and CENP-A nucleosomes are accentuated by reversible deformation under high pressure | | 评估生成扩散模型在跨尺度和全原子分辨率下对折叠和无序蛋白质状态的增强采样能力 | Bera, P. | PDF | N/A | Assessing Generative Diffusion Models for Enhanced Sampling of Folded and Disordered Protein States Across Scales and in All-atom Resolution | | 使用马尔可夫状态模型揭示组蛋白尾部的构象动力学 | Patel, R. | PDF | N/A | Unveiling the Conformational Dynamics of the Histone Tails Using Markov State Modeling | | ADAR1通过MDM2调控脂质重塑以决定铁死亡敏感性 | Kung, C.-P. | PDF | N/A | ADAR1 Regulates Lipid Remodeling through MDM2 to Dictate Ferroptosis Sensitivity | | 产前大麻素暴露影响年轻雄性和雌性大鼠的中枢心肺控制 | Patrone, L. G. 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T. | PDF | N/A | A single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists | | 抑制血管紧张素转换酶的N端催化域可以防止脑组织中内源性阿片类物质的降解。 | Hanak, F. | PDF | N/A | Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue | | 抗Caspr2抗体的异质性：特异性与致病性 | Su, J. | PDF | N/A | Heterogeneity of anti-Caspr2 antibodies: specificity and pathogenicity | | 移植前靶向TNFRSF25和CD25可刺激目标组织中的受体调节性T细胞（Tregs），从而改善造血干细胞移植（HSCT）后的移植物抗宿主病（GVHD）。 | McManus, D. | PDF | N/A | Pretransplant targeting of TNFRSF25 and CD25 stimulates recipient Tregs in target tissues ameliorating GVHD post-HSCT | | 一种非人灵长类动物模型模拟了人类先天性巨细胞病毒感染，并揭示了垂直传播结果的全谱。 | Manuel, T. D. | PDF | N/A | A nonhuman primate model mirrors human congenital cytomegalovirus infection and reveals a spectrum of vertical transmission outcomes | | 定义灵长类动物卵巢储备的细胞和分子起源 | Wamaitha, S. E. | PDF | N/A | Defining the cell and molecular origins of the primate ovarian reserve | | 四核苷酸频率区分环境微生物组中的基因组边界和代谢策略 | Kellom, M. | PDF | N/A | Tetranucleotide frequencies differentiate genomic boundaries and metabolic strategies across environmental microbiomes | | 表观遗传因子Zrf1在中肠再生过程中调节肠道干细胞的增殖 | Li, J. S. S. | PDF | N/A | The epigenetic factor Zrf1 regulates intestinal stem cell proliferation during midgut regeneration | | 大肠杆菌中兼职蛋白的近端关系：数学基因组学视角 | NAWN, D. | PDF | N/A | Proximal relationships of moonlighting Proteins in Escherichia coli: a mathematical genomic perspective | | 上呼吸道上皮单细胞图谱揭示了细胞类型和模式策略的异质性 | Sun, X. | PDF | N/A | A Single-Cell Atlas of the Upper Respiratory Epithelium Reveals Heterogeneity in Cell Types and Patterning Strategies | | 探索非裔美国女性中高血压与肾功能之间的转录组学交叉景观 | Abbas, M. | PDF | N/A | Intersecting Transcriptomic Landscapes of Hypertension and Kidney Function in African American Women | | 在Furfurilactobacillus中发现了一个分歧的肉毒杆菌神经毒素样基因簇 | Wei, X. | PDF | N/A | Identification of a divergent botulinum neurotoxin like gene cluster in Furfurilactobacillus | | 使用可解释的机器学习方法解码PTEN错义突变在癌症和自闭症谱系障碍中的机制 | Yang, M. | PDF | N/A | Decoding Mechanisms of PTEN Missense Mutations in Cancer and Autism Spectrum Disorder using Interpretable Machine Learning Approaches | | 在牛津纳米孔技术测序仪上使用R2C2和Chopper方法对完整质粒进行测序和组装 | Schimke, K. D. | PDF | N/A | Sequencing and assembling complete plasmids on Oxford Nanopore Technology Sequencers using R2C2 and Chopper | | 静态三维结构决定间期染色体远端位点对之间的快速动态 | Shi, G. | PDF | N/A | Static Three-Dimensional Structures Determine Fast Dynamics Between Distal Loci Pairs in Interphase Chromosomes | | 二维蛋白质二聚化的结合亲和力受益于焓的稳定作用。 | Jhaveri, A. | PDF | N/A | Binding affinities for 2D protein dimerization benefit from enthalpic stabilization | | 对肠道中吞咽空气量的量化研究发现，睡眠时空气量较低可能会减少有氧消化，这解释了为什么晚餐后短时间内入睡与夜间反流有关。 | Hurr, T. J. | PDF | N/A | Quantification of the volume of swallowed air in the gut finds low volumes when asleep may reduce aerobic digestion and explain why short dinner to sleep times are associated with nocturnal reflux | | 监测杀菌剂抗性频率——以大麦网斑病为例 | Knight, N. L. | PDF | N/A | Monitoring fungicide resistance frequencies -- a case study of barley net blotch | | 沿着厚壁升支的不同细胞类型表达单价和二价阳离子转运的途径。 | Bahena-Lopez, J. | PDF | N/A | Distinct cell types along thick ascending limb express pathways for monovalent and divalent cation transport | | 衰老、耐力训练和去神经对骨骼肌先天免疫信号的影响 | Khemraj, P. | PDF | N/A | Effect of aging, endurance training, and denervation on innate immune signaling in skeletal muscle | | 针对APOE3-Christchurch纯合子星形胶质细胞的阿尔茨海默病保护机制 | Tian, X. | PDF | N/A | Protective mechanisms against Alzheimer's Disease in APOE3-Christchurch homozygous astrocytes | | 使用实验设计进行人类原代B细胞培养的多参数优化 | Rovsing, A. B. | PDF | N/A | Multiparametric optimization of human primary B-cell cultures using Design of Experiments | | 比较基于mRNA、腺病毒血清型25和黄热病疫苗株嵌合体的蜱传脑炎病毒候选疫苗 | Kuznetsova, N. A. | PDF | N/A | Comparison candidate Tick-borne encephalitis virus vaccines based on mRNA, adenovirus serotype 25 and chimera of YFV vaccine strain | | 瞬态pH变化驱动酶-聚合物凝聚体中的液泡形成 | Modi, N. | PDF | N/A | Transient pH changes drive vacuole formation in enzyme-polymer condensates | | 通过47个高分辨率基因组组装揭示白蚁进化 | Liu, C. | PDF | N/A | Unravelling termite evolution with 47 high-resolution genome assemblies | | 最初为工业应用合成的光活性化合物的新型抗菌活性 | Ezquerra-Aznarez, J. M. | PDF | N/A | Novel antimicrobial activity of photoactive compounds originally synthesized for industrial applications | | 木霉菌（Trichoderma atroviride，属于肉座菌目：肉座菌科）对白纹伊蚊（Aedes albopictus，属于双翅目：蚊科）的杀幼虫活性研究 | Hayes, D. T. | PDF | N/A | Larvicidal activity of Trichoderma atroviride (Hypocreales: Hypocreaceae) against Aedes albopictus (Diptera: Culicidae) | | 肠道竞争动态：活菌疗法的效果受微生物组复杂性、饮食和治疗性转基因的影响 | Siguenza, N. | PDF | N/A | Gut Competition Dynamics of Live Bacterial Therapeutics Are Shaped by Microbiome Complexity, Diet, and Therapeutic Transgenes | | 开发用于拉科罗斯病毒检测的RT-RPA检测方法为小鼠年龄依赖性神经侵袭提供了见解 | Lumkong, L. | PDF | N/A | Development of an RT-RPA assay for La Crosse virus detection provides insights into age-dependent neuroinvasion in mice | | 利用内源性Cas9基因编辑技术对鼠李糖乳杆菌GG（LGG）进行精准食品发酵和活体生物治疗的研究 | Xie, Z. | PDF | N/A | Exploiting Endogenous Cas9-Based Genome Editing of Lacticaseibacillus rhamnosus GG (LGG) for Precision Food Fermentation and Live Biotherapeutics | | 一个类似于LexA的阻遏蛋白和全局性的H-NS样调节因子使得环境中的假单胞菌能够精细调控R-tailocin的表达。 | Heiman, C. M. | PDF | N/A | A LexA-like repressor and global H-NS-like regulators enable the fine-tuning of R-tailocin expression in environmental Pseudomonas | | 人类母乳低聚糖通过梭菌属物种的代谢抑制炎症和病原体生长 | Chapman, J. A. | PDF | N/A | Human milk oligosaccharide metabolism by Clostridium species suppresses inflammation and pathogen growth | | 宿主环境塑造丝虫寄生虫的适应性与沃尔巴克氏体共生动态 | FERCOQ, F. | PDF | N/A | Host environment shapes filarial parasites fitness and Wolbachia endosymbionts dynamics | | 局部核仁监视机制维持rDNA稳定性 | Liu, R. | PDF | N/A | Local nucleolar surveillance mechanisms maintain rDNA stability | | 诊断感染辣椒和番茄植物的黄单胞菌的特异性遗传标记 | Can, A. | PDF | N/A | The Specific Genetic Markers to Diagnose Xanthomonads Infecting Pepper and Tomato Plants | | 通过限制基因编辑表达的组织范围来最小化基因编辑的脱靶效应 | Kim, N.-G. | PDF | N/A | Minimization of gene editing off-target effects by tissue restriction of expression | | 有证据表明，SARS-CoV-2病毒的刺突蛋白（S蛋白）可能针对多种细胞骨架及细胞骨架相关蛋白的卷曲螺旋区域。 | Brezellec, P. | PDF | N/A | Evidence suggests that the SARS-CoV-2 Spike (S) protein may target coiled-coil regions of numerous cytoskeletal and cytoskeleton-associated proteins | | 磷酸肌醇和Collybistin依赖的Gephyrin突触聚集 | Burdina, N. | PDF | N/A | Phosphoinositide- and Collybistin-Dependent Synaptic Clustering of Gephyrin | | 糖生物学中的蛋白质-聚糖相互作用及跨手性识别的原子级机制 | Carpenter, E. J. | PDF | N/A | Atom-level Machine of Protein-glycan Interactions and Cross-chiral Recognition in Glycobiology | | 副斑蛋白NONO通过变构刺激NSD1来调节活性染色质 | Hsu, C.-I. | PDF | N/A | Paraspeckle Protein NONO Regulates Active Chromatin by Allosterically Stimulating NSD1 | | 氮酶催化辅因子的分子分选 | Salinero-Lanzarote, A. | PDF | N/A | Molecular sorting of nitrogenase catalytic cofactors | | USP1作为HSFA2的伴侣蛋白，在拟南芥的热启动过程中起着至关重要的作用。 | Hirt, H. | PDF | N/A | USP1 acts as a chaperone for HSFA2 and plays a crucial role in thermopriming in Arabidopsis | | 一氧化碳暴露刺激了多种土壤生态系统中初级生产者的生长和活性。 | Xu, Y. | PDF | N/A | Carbon monoxide exposure stimulates growth and activity of primary producers in diverse soil ecosystems | | 肽设计通过结合界面模拟 | Kong, X. | PDF | N/A | Peptide Design through Binding Interface Mimicry | | 海藻酸-ε聚赖氨酸核壳水凝胶珠作为一种有效、稳定且可扩展的微生物封装工具 | Amaro-Cruz, A. | PDF | N/A | Alginate-ϵPLL core-shell hydrogel beads as a tool for an effective, stable and scalable microbial encapsulation | | 重新审视CAR T细胞工程中对mRNA核苷修饰的需求 | Kahwaji, N. | PDF | N/A | Revisiting the need for mRNA nucleoside modification in CAR T cell engineering | | 零样本、大样本、主动样本——如何懒散地估计细胞汇合度 | Joas, M. J. | PDF | N/A | Zero-Shot, Big-Shot, Active-Shot - How to estimate cell confluence, lazily | | 离子化脂质纳米颗粒转染效率的缓冲特异性与体相转变 | Carucci, C. | PDF | N/A | Buffer specificity of ionizable lipid nanoparticle transfection efficiency and bulk phase transition | | 小分子控制的基因表达：设计针对定制核糖开关的药物样高亲和力小分子调节剂 | Hedwig, V. | PDF | N/A | Small molecule-controlled gene expression: Design of drug-like high affinity small molecule modulators of a custom-made riboswitch | | 全局转录组分析发现烟酰胺代谢在干扰素-γ和一氧化氮调控的反应中起关键作用。 | Chattopadhyay, A. | PDF | N/A | Global transcriptome analysis identifies nicotinamide metabolism to play key roles in IFN-gamma and nitric oxide modulated responses | | 以下是您提供的英文文本的中文翻译：

GC-MS分析与体外抗菌、抗生物膜和抗粘附活性：柽柳（Tamarix ericoides Rottl.）叶提取物对导管相关尿路感染病原体的作用

翻译说明：
- GC-MS Profiling：GC-MS分析，指通过气相色谱-质谱联用技术对样品成分进行分析。
- In vitro：体外实验，指在实验室条件下进行的非活体实验。
- Antibacterial：抗菌，指抑制或杀灭细菌的能力。
- Anti-Biofilm：抗生物膜，指抑制细菌形成生物膜的能力。
- Anti-adhesive：抗粘附，指抑制细菌粘附到表面的能力。
- Tamarix ericoides Rottl.：柽柳（学名），一种植物。
- Catheter-Associated Urinary Tract Infectious Agents：导管相关尿路感染病原体，指因使用导管而引发的尿路感染相关病原体。

BioRxiv 2025-01-20 Papers

标题	作者	PDF链接	代码仓库	Title
原代肠道成纤维细胞的长程组织引导了类器官来源的肠道上皮细胞的定向和持续迁移。	Fernandez-Majada, V.	PDF	N/A	Long-range organization of primary intestinal fibroblasts guides directed and persistent migration of organoid-derived intestinal epithelia
多模态系统用于记录鸣禽群体中的个体行为	Rüttimann, L.	PDF	N/A	Multimodal system for recording individual-level behaviors in songbird groups
电刺激调节未能增强交感神经轴突的再生	Tian, T.	PDF	N/A	Conditioning electrical stimulation fails to enhance sympathetic axon regeneration
漂流瀑布：人工选择的集体组成可能成功或失败，这取决于初始值和目标值。	Lee, J.	PDF	N/A	Rafting a waterfall: Artificial selection for collective composition can succeed or fail depending on the initial and target values
解构复杂性：利用tviblindi计算拓扑方法对人类胸腺轨迹推断的研究	Stuchly, J.	PDF	N/A	Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi
四对单独识别的多巴胺神经元在果蝇幼虫中传递味觉惩罚信号	Weber, D.	PDF	N/A	Four Individually Identified Paired Dopamine Neurons Signal Taste Punishment in Larval Drosophila
视觉序列暴露引发的人脑中非特征特异性增强反应与特征特异性反向回放	He, T.	PDF	N/A	Non-feature-specific elevated responses and feature-specific backward replay in human brain induced by visual sequence exposure
扩张型心肌病相关的RNA结合基序蛋白20在神经元中调控长前体mRNA。	Di Bartolomei, G.	PDF	N/A	Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons
塑造物理世界以适应我们的需求：左侧PF技术认知区域	Osiurak, F.	PDF	N/A	Shaping the physical world to our ends: The left PF technical-cognition area
以下是这段英文的中文翻译：

斑马鱼幼体行为变异的全脑神经基础

翻译解释： - "Whole-brain" 翻译为“全脑”，指的是整个大脑。 - "neural substrates" 翻译为“神经基础”或“神经基质”，指的是与某种功能或行为相关的神经机制或结构。 - "behavioral variability" 翻译为“行为变异”，指的是个体在行为上的差异或变化。 - "larval zebrafish" 翻译为“斑马鱼幼体”，指的是斑马鱼的幼虫阶段。

摘要： 理解信息如何在脑网络中传递对于揭示认知功能和神经系统疾病的机制至关重要。然而，目前尚缺乏一个通用框架来定量描述脑网络中的最优通信模式。本研究提出了一种基于信息论和网络科学的通用框架，用于表征脑网络中的最优通信。该框架将脑网络建模为信息传输系统，并定义了衡量通信效率的指标。我们利用该框架分析了不同任务状态下的大脑活动数据，识别出与最优通信相关的关键网络特征。结果表明，该框架能够有效捕捉脑网络通信的动态变化，并为理解脑功能提供新的见解。

关键词： 脑网络，最优通信，信息论，网络科学，功能连接

1. 引言

大脑是一个复杂的网络系统，由数十亿个神经元通过突触连接相互连接。信息在这些网络中高效传递对于实现各种认知功能至关重要。近年来，随着神经影像技术和网络分析方法的快速发展，研究者们开始从网络科学的角度研究脑功能组织，并取得了显著进展。然而，如何定量描述脑网络中的最优通信模式仍然是一个挑战。

2. 方法

2.1 脑网络建模

我们将脑网络建模为一个加权有向图，其中节点代表脑区，边代表脑区之间的功能连接强度。功能连接强度可以通过计算不同脑区时间序列之间的统计相关性来估计。

2.2 信息传输模型

我们采用信息论中的互信息来衡量脑区之间的信息传递量。互信息量化了两个随机变量之间的统计依赖性，可以反映一个脑区的活动对另一个脑区活动的预测能力。

2.3 最优通信指标

为了衡量脑网络的通信效率，我们定义了以下指标：

全局通信效率： 衡量信息在整个网络中传播的平均效率。
局部通信效率： 衡量信息在网络局部区域传播的效率。
通信成本： 衡量维持网络通信所需的资源消耗。

3. 结果

我们将该框架应用于分析不同任务状态下的大脑活动数据。结果表明：

在不同任务状态下，脑网络的通信效率表现出显著差异。
与静息态相比，任务态下脑网络的全局通信效率和局部通信效率均显著提高。
识别出了一些与最优通信相关的关键网络特征，例如网络模块化和核心-边缘结构。

4. 讨论

本研究提出的通用框架为定量描述脑网络中的最优通信模式提供了新的工具。该框架能够有效捕捉脑网络通信的动态变化，并为理解脑功能提供新的见解。未来研究可以进一步将该框架应用于研究神经系统疾病的机制，以及开发新的脑机接口技术。

5. 结论

本研究提出了一种基于信息论和网络科学的通用框架，用于表征脑网络中的最优通信。该框架为理解脑功能组织提供了新的视角，并具有广泛的应用前景。 | Fakhar, K. | PDF | N/A | A General Framework for Characterizing Optimal Communication in Brain Networks | | 生物分子凝聚体可以增强同型RNA的聚集 | Mahendran, T. S. | PDF | N/A | Biomolecular Condensates Can Enhance Homotypic RNA Clustering | | 在不同时间尺度上，正常听力和听力受损听众的多说话者语音理解 | Li, J. | PDF | N/A | Multi-talker speech comprehension at different temporal scales in listeners with normal and impaired hearing | | 转录因子DksA和PsrA在嗜肺军团菌（L. pneumophila）对阿米巴原虫（Acanthamoeba castellanii）的毒力中具有协同作用。 | Graham, C. I. | PDF | N/A | Transcription Factors DksA and PsrA are synergistic contributors to L. pneumophila virulence in Acanthamoeba castellanii protozoa | | 以下是这段英文的中文翻译：

西帕加明作为抗巴贝斯虫候选药物的功效和作用机制

翻译说明： - "Efficacy" 翻译为 "功效" - "mechanism of action" 翻译为 "作用机制" - "cipargamin" 是药物名称，音译为 "西帕加明" - "antibabesial drug candidate" 翻译为 "抗巴贝斯虫候选药物"

希望这对你有帮助！ | Li, H. | PDF | N/A | Efficacy and mechanism of action of cipargamin as an antibabesial drug candidate | | 干扰新生脂肪生成阻碍了MERS-CoV（中东呼吸综合征冠状病毒）的组装和释放，但不影响病毒复制细胞器的生物发生。 | Soultsioti, M. | PDF | N/A | Perturbation of de novo lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles | | 疼痛分布可以通过经典条件反射来确定。 | Nastaj, J. | PDF | N/A | Pain distribution can be determined by classical conditioning | | 从旋转平均的二维X射线衍射图案中恢复昆虫飞行肌肉的三维结构 | Iwamoto, H. | PDF | N/A | Restoration of 3-D structure of insect flight muscle from a rotationally averaged 2-D X-ray diffraction pattern | | 中欧永续农业的作物生产力介于有机农业和传统农业之间。 | Reiff, J. | PDF | N/A | Crop productivity of Central European Permaculture is within the range of organic and conventional agriculture. | | 通过单细胞空间分析在人类肺部组织中鉴定出SPP1阳性巨噬细胞，这些组织受到分枝杆菌感染。 | Katano, H. | PDF | N/A | Identification of SPP1-positive macrophages by single-cell spatial analysis in human lung tissues with mycobacterial infection | | 体感皮层与身体表征：在视觉-本体感受线索冲突中更新运动系统 | Mirdamadi, J. L. | PDF | N/A | Somatosensory cortex and body representation: Updating the motor system during a visuo-proprioceptive cue conflict | | CXXC指蛋白1与FOXP3结合，以稳定调节性T细胞的稳态和抑制功能。 | Meng, X. | PDF | N/A | CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells | | CXXC指蛋白1与FOXP3结合，以稳定调节性T细胞的稳态和抑制功能。 | Meng, X. | PDF | N/A | CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells | | 关于D1/V185残基在集胞藻6803和嗜热聚球藻中参与光系统II功能的新见解。 | Boussac, A. | PDF | N/A | New insights into the involvement of residue D1/V185 in Photosystem II function in Synechocystis 6803 and Thermosynechococcus vestitus. | | 更多细胞，更多双联体在高通量单细胞数据中 | Howitt, G. | PDF | N/A | More cells, more doublets in highly multiplexed single-cell data | | 对未经治疗的人类非小细胞肺癌（NSCLC）进行光学成像揭示了与转移性复发相关的变化。 | Diaz, P. M. | PDF | N/A | Optical imaging of treatment-naive human NSCLC reveals changes associated with metastatic recurrence | | Rag2Mol：基于检索增强生成的结构化药物设计 | Zhang, P.-D. | PDF | N/A | Rag2Mol: Structure-based drug design based on Retrieval Augmented Generation | | Rag2Mol：基于检索增强生成的结构化药物设计 | Zhang, P.-D. | PDF | N/A | Rag2Mol: Structure-based drug design based on Retrieval Augmented Generation | | Neuroligin 3 突显了果蝇社交距离中的性别二态性神经回路 | Robinson, J. W. | PDF | N/A | Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing | | 植物内化学防御的变异并不能解释小菜蛾（Plutella xylostella）对桂竹香（Erysimum cheiranthoides）的取食偏好。 | Zuest, T. | PDF | N/A | Within-plant variation in chemical defence of Erysimum cheiranthoides does not explain Plutella xylostella feeding preference | | FlowDesign：通过流匹配和更好的先验分布改进抗体CDR设计 | Wu, J. | PDF | N/A | FlowDesign: Improved Design of Antibody CDRs Through Flow Matching and Better Prior Distributions | | 使用MMseqs2进行GPU加速的同源性搜索 | Kallenborn, F. | PDF | N/A | GPU-accelerated homology search with MMseqs2 | | 蛋白质晶体结构和AlphaFold预测模型的分子表面几何特性 | Wang, L. | PDF | N/A | The geometric properties of the molecular surfaces of protein crystal structures and AlphaFold predicted models | | 大脑特征图揭示了腹侧流中逐步的动物特征表征。 | Zhang, Z. | PDF | N/A | Brain Feature Maps Reveal Progressive Animal-Feature Representations in the Ventral Stream. | | 稳态和刺激状态下人类骨骼肌细胞中代谢性状相关基因调控的功能解析 | Nishino, K. | PDF | N/A | Functional dissection of metabolic trait-associated gene regulation in steady state and stimulated human skeletal muscle cells | | 将免疫滚环扩增技术应用于印刷糖芯片上ABO血型抗体的高灵敏度检测。 | Kornilova, E. E. | PDF | N/A | The applying of immuno-RCA for the high-sensitivity detection of the ABO blood group antibodies on the printed glycoarray | | 伤寒沙门氏菌的伤寒毒素在急性伤寒期间引发宿主的抗菌反应 | Srour, S. | PDF | N/A | Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever | | 极低水活性条件下的生命极限：太阳能盐场中的锂浓度池（智利阿塔卡马盐沼） | Demergasso, C. | PDF | N/A | The limit of life at extremely low water activity: Lithium-concentration ponds in a solar saltern (Salar de Atacama, Chile) | | 通过对1,027个长读长基因组进行详细的串联重复等位基因分析，揭示了全基因组范围内的致病性模式。 | Danzi, M. C. | PDF | N/A | Detailed tandem repeat allele profiling in 1,027 long-read genomes reveals genome-wide patterns of pathogenicity | | 单细胞RNA测序揭示了克氏锥虫群体中跨唾液酸酶样超家族基因表达的异质性 | Inchausti, L. | PDF | N/A | Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations | | 无标记检测与表征新鲜和冷冻保存巨噬细胞的代谢 | Canales, D. D. H. | PDF | N/A | Label-free Detection and Characterization of Metabolism in Fresh and Cryopreserved Macrophages | | 具核梭杆菌通过一种表观遗传现象决定了苯丙胺诱导的行为反应的表达。 | Mabry, S. J. | PDF | N/A | Fusobacterium nucleatum determines the expression of amphetamine-induced behavioral responses through an epigenetic phenomenon. | | 脂质锥超家族：脂质、肽聚糖和外多糖代谢、生物间冲突与免疫的统一主题 | Burroughs, A. M. | PDF | N/A | The Lipocone Superfamily: A Unifying Theme In Metabolism Of Lipids, Peptidoglycan And Exopolysaccharides, Inter-Organismal Conflicts And Immunity | | Innexin 7间隙连接蛋白有助于果蝇触角叶中的同步活动，并调节嗅觉功能。 | Fuenzalida-Uribe, N. | PDF | N/A | The Innexin 7 gap junction protein contributes to synchronized activity in the Drosophila antennal lobe and regulates olfactory function | | 微生物代谢进化过程中多物种群落的稳定性 | Kehila, D. | PDF | N/A | Stability of multi-species consortia during microbial metabolic evolution | | 3D打印磁悬浮装置结合深度学习辅助的颗粒追踪与分析技术，用于高通量分选 | Ramarao, M. | PDF | N/A | 3D-Printed Magnetic Levitation Device with Deep Learning-Assisted Particle Tracking and Analysis for High-Throughput Sorting | | 使用语言模型对生物数据集进行元数据协调 | Verbitsky, A. | PDF | N/A | Metadata Harmonization from Biological Datasets with Language Models | | 头颈癌中的DNA聚合酶β表达调节了聚(ADP-核糖)介导的复制检查点 | Khan, M. M. | PDF | N/A | DNA polymerase beta expression in head & neck cancer modulates the poly(ADP-ribose)-mediated replication checkpoint | | 年龄和性别特异性对骨骼肌和心肌中线粒体质量控制的影响 | Springer-Sapp, C. B. | PDF | N/A | Age and Sex-Specific Changes in Mitochondrial Quality Control in Skeletal and Cardiac Muscle | | 将SMN2剪接修饰剂与HDAC6抑制剂结合使用，可显著改善脊髓性肌萎缩症患者的肌肉功能和生存率。 | Osseni, A. | PDF | N/A | Combining SMN2 splicing modifiers with HDAC6 inhibition greatly improves muscle function and survival in Spinal Muscular Atrophy | | 预测编码算法在人工神经网络中引发了类似大脑的反应。 | Gutlin, D. C. | PDF | N/A | Predictive Coding algorithms induce brain-like responses in Artificial Neural Networks | | 长期海马低频刺激可缓解癫痫小鼠的局灶性癫痫发作、记忆缺陷和突触病理。 | Kleis, P. | PDF | N/A | Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic mice | | Hsp70分子伴侣Ssa1和Ssa2限制多聚腺苷酸结合蛋白的聚集。 | Buchholz, H. E. | PDF | N/A | Hsp70 chaperones, Ssa1 and Ssa2, limit poly(A) binding protein aggregation | | 化疗药物紫杉醇在间期的作用机制：核破坏 | Hale, T. | PDF | N/A | Nuclear Disruption as a Mechanism of the Chemotherapeutic Drug Paclitaxel in Interphase | | 性别不影响小鼠在整个衰老过程中的神经元自噬 | Rodruiguez, M. N. | PDF | N/A | Sex does not Influence Neuronal Autophagy throughout Aging in Mice | | 端粒SUMO水平影响APB形成途径的选择和ALT效率 | Zhao, R. | PDF | N/A | Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency | | 富含支链脂肪酸的饮食促进脂滴增大并影响秀丽隐杆线虫的机体健康 | Li, K. U. R. | PDF | N/A | Branched chain fatty acid-rich diet promotes lipid droplet enlargement and impacts organismal health in Caenorhabditis elegans | | 组蛋白去乙酰化酶-1对于粗糙脉孢菌（Neurospora crassa）的表观基因组稳定性是必需的。 | Ebot-Ojong, F. | PDF | N/A | Histone deacetylase-1 is required for epigenome stability in Neurospora crassa | | Reg-GPTTM：一种用于增强再生医学决策的对话式人工智能模型 | Maharaj, D. | PDF | N/A | Reg-GPTTM: A Conversational AI Model for Enhanced Decision-Making in Regenerative Medicine | | hmde：微分方程的层次方法 | O'Brien, T. A. | PDF | N/A | hmde: Hierarchical Methods for Differential Equations | | 帕金森病中人类背侧纹状体少突胶质细胞的易损性 | Reyes, J. M. B. | PDF | N/A | Oligodendroglia vulnerability in the human dorsal striatum in Parkinson's disease | | 肝脏生物钟调节骨骼肌中的转录节律，以调控线粒体功能。 | Sica, V. | PDF | N/A | The liver clock tunes transcriptional rhythms in skeletal muscle to regulate mitochondrial function | | 心肌细胞中Klf9的组成型表达导致代谢功能障碍和自发性心力衰竭。 | Thakkar, C. | PDF | N/A | Constitutive expression of cardiomyocyte Klf9 precipitates metabolic dysfunction and spontaneous heart failure. | | Plakophilin-2在心肌细胞中协调能量代谢和收缩功能，揭示其在桥粒之外的作用 | Aycinena, J. A. | PDF | N/A | Plakophilin-2 Coordinates Energy Metabolism and Contractility in Cardiomyocytes, Revealing Its Roles beyond Desmosomes | | 无饲养层培养法下保持胚胎、胚胎外及类囊胚生成潜能的人类原始多能干细胞培养 | Rossignoli, G. | PDF | N/A | Feeder-free culture of naive human pluripotent stem cells retaining embryonic, extraembryonic and blastoid generation potential | | 小细胞外囊泡在调节贾第虫对甲硝唑耐药性中的基因型特异性作用 | Luna Pizarro, G. | PDF | N/A | Genotype-specific roles of small extracellular vesicles in modulating metronidazole resistance in Giardia lamblia | | 荧光蛋白相互作用稳定化用于正交RNA成像 | Zhou, W.-J. | PDF | N/A | Fluorogenic Interacting Protein Stabilization for Orthogonal RNA Imaging | | HoloMoA：一种基于快速全息成像和深度学习的工具，用于检测抗菌候选药物作用机制的新颖性 | Sedaghat, Z. | PDF | N/A | HoloMoA: Fast holography and deep-learning-based tool for the novelty detection of mechanism of action of antimicrobial candidates | | 具有固定和可变色素的海洋聚球藻菌株之间的光色竞争 | Dufour, L. | PDF | N/A | Competition for light color between marine Synechococcus strains with fixed and variable pigmentation | | Chameau (HBO1) 在果蝇中以温度依赖的方式调控饥饿反应。 | Venkatasubramani, A. V. | PDF | N/A | Chameau (HBO1) regulates starvation in a temperature-dependent manner in Drosophila melanogaster | | 在塑造实验性动物流行病的过程中，感染宿主的竞争力掩盖了易感性异质性的影响。 | Perez-Umphrey, A. | PDF | N/A | Infected host competence overshadows heterogeneity in susceptibility in shaping experimental epizootics | | 利用祖先重组图对籼稻和粳稻亚种的产量进行定量遗传分析 | Rebollo, I. | PDF | N/A | Leveraging ancestral recombination graphs for quantitative genetic analysis of rice yield in indica and japonica subspecies | | 以下是这段文字的中文翻译：

使用数据非依赖采集方法自动化氢/氘交换质谱测量的建议

这段文字主要讨论如何通过数据非依赖采集（Data-Independent Acquisition, DIA）方法来实现氢/氘交换质谱（Hydrogen/Deuterium Exchange Mass Spectrometry, HDX-MS）测量的自动化，并提供相关建议。 | Filandr, F. | PDF | N/A | Recommendations for Automating Hydrogen/Deuterium Exchange Mass Spectrometry Measurements using Data-Independent Acquisition Methods | | 单细胞数字孪生技术在阿尔茨海默病中识别药物靶点及可重新利用的药物 | Ren, Y. | PDF | N/A | Single-cell digital twins identify drug targets and repurposable medicine in Alzheimers disease | | 头颈癌中的HPV整合：与不良预后相关的下游剪接事件及表达比例 | Li, S. | PDF | N/A | HPV integration in head and neck cancer: downstream splicing events and expression ratios linked with poor outcomes | | TMPRSS2-ERG赋予抗雄激素药物耐药性：机制及治疗意义

TMPRSS2-ERG基因融合在前列腺癌中较为常见，这种融合基因不仅与肿瘤的发生发展密切相关，还可能导致肿瘤对某些治疗药物产生耐药性。具体来说，TMPRSS2-ERG融合基因的存在可能使前列腺癌细胞对雄激素剥夺治疗（ADT）和抗雄激素药物（如恩杂鲁胺和阿比特龙）产生抵抗，从而影响治疗效果。

机制： 1. 雄激素受体（AR）信号通路激活：TMPRSS2-ERG融合基因可能通过直接或间接方式激活AR信号通路，即使在雄激素水平较低的情况下，也能维持AR的活性，从而促进肿瘤细胞的生长和存活。 2. 基因表达调控：TMPRSS2-ERG融合蛋白可能通过调控下游基因的表达，改变细胞的代谢、增殖和凋亡过程，进而增强肿瘤细胞的生存能力。 3. 肿瘤微环境改变：TMPRSS2-ERG融合基因可能通过影响肿瘤微环境中的细胞间相互作用，促进肿瘤细胞的侵袭和转移。

治疗意义： 1. 靶向TMPRSS2-ERG的治疗策略：针对TMPRSS2-ERG融合基因的特异性抑制剂或基因编辑技术（如CRISPR-Cas9）可能成为未来治疗耐药性前列腺癌的有效手段。 2. 联合治疗：将抗雄激素药物与其他靶向药物（如PARP抑制剂或PI3K/AKT/mTOR通路抑制剂）联合使用，可能克服TMPRSS2-ERG介导的耐药性。 3. 生物标志物检测：在治疗前检测TMPRSS2-ERG融合基因的存在，有助于制定个体化治疗方案，提高治疗效果。

总之，TMPRSS2-ERG融合基因在前列腺癌的耐药机制中扮演了重要角色，深入研究其作用机制并开发针对性的治疗策略，对于改善前列腺癌患者的预后具有重要意义。 | Sekar, A. | PDF | N/A | TMPRSS2-ERG confers resistance to antiandrogens: mechanism and therapeutic implications | | 通过心血管磁共振检测弥漫性至局灶性心肌纤维化与小型猪组织学对比 | Zhang, H. | PDF | N/A | Detection of Diffuse to Focal Myocardial Fibrosis by Cardiovascular Magnetic Resonance Against Histology in Mini-Swine | | 系统发育、民族药用及豆科植物中植物雌激素的分布 | Thaweepanyaporn, K. | PDF | N/A | Phylogeny, ethnomedicinal use and the distribution of phytoestrogens in the Fabaceae | | 自身抗体热点揭示了免疫原性XIST核糖核蛋白复合物的起源和影响 | Yan, B. | PDF | N/A | Autoantibody hotspots reveal origin and impact of immunogenic XIST ribonucleoprotein complex | | 从人类HIV-1疫苗试验参与者中分离出的糖链反应性抗体显示出广泛的病原体交叉反应性。 | Jamieson, P. J. | PDF | N/A | Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity | | 利用粪便挥发性物质分析技术，对野生和圈养白尾鹿进行敏感且非侵入性的慢性消耗病检测 | Berna, A. Z. | PDF | N/A | Sensitive, non-invasive detection of chronic wasting disease in wild and captive white-tailed deer using fecal volatile profiling | | 验证和多方部署用于撒哈拉以南非洲地区禽流感和狂犬病分子诊断的冻干qRT-PCR试剂 | Drzewniokova, P. | PDF | N/A | Validation and multi-site deployment of a lyophilized qRT-PCR reagent for the molecular diagnosis of avian influenza and rabies in Sub-Saharan African regions | | 过去二十年间应用不育昆虫技术控制鳞翅目害虫的研究进展：系统综述 | Bambo, K. K. | PDF | N/A | Research advancements on the application of sterile insect technique for the control of lepidopteran pests over the past two decades: A Systematic Review | | SPARC是一种通过TGF-β依赖性机制驱动早期乳腺肿瘤进展的新因子。 | Sciacca, M. | PDF | N/A | SPARC is a new driver of early breast tumor progression via TGF-β -dependent mechanism. | | AuthormetriX：从Scopus语料库中自动计算个体作者的非通胀性信用分配方案和合作指标 | Adeosun, S. O. | PDF | N/A | AuthormetriX: Automated Calculation of Individual Authors' Non-Inflationary Credit-Allocation Schemas' and Collaboration Metrics from a Scopus Corpus | | C端标记、跨膜结构域的疏水性以及内质网保留基序影响内核膜蛋白emerin的分泌运输 | Mella, J. | PDF | N/A | C-terminal tagging, transmembrane domain hydrophobicity, and an ER retention motif influence the secretory trafficking of the inner nuclear membrane protein emerin | | H3K4甲基化促进的转录记忆确保了合子基因组的忠实激活和胚胎发育 | Oak, M. S. | PDF | N/A | H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development | | 基于恐惧和消退神经回路动力学的焦虑障碍正式模型 | rubin, a. l. | PDF | N/A | A formal model of anxiety disorders based on the neural circuit dynamics of the fear and extinction circuits | | 一条胆碱能脊髓通路用于呼吸的适应性控制 | Lin, M. | PDF | N/A | A cholinergic spinal pathway for the adaptive control of breathing | | 基于触摸屏的Go/No Go任务用于评估小鼠认知判断偏差的特性研究：一种用于情感状态障碍药物筛选的新型转化工具。 | Lopez-Cruz, L. | PDF | N/A | Characterisation of a touchscreen-based Go/No Go task for assessing cognitive judgement bias in mice: a new translational tool for affective state disorder drug screening. | | 选择性消化道去污对ESBL大肠杆菌全基因组组成的影响 | Paganini, J. A. | PDF | N/A | Impact of selective digestive decontamination on the pangenome composition of ESBL-E. coli | | 发育中的脑回脑在遭受严重创伤性脑损伤（TBI）后，NKCC1在急性时间、特定区域及细胞类型上的破坏。 | Hochstetler, A. E. | PDF | N/A | Acute temporal, regional, and cell-type specific NKCC1 disruption following severe TBI in the developing gyrencephalic brain. | | 在表示学习过程中任务相似性对大脑和神经网络的影响 | Menghi, N. | PDF | N/A | The effects of task similarity during representation learning in brains and neural networks | | CB2受体与NMDA受体在帕金森病中的相互作用 | Lillo, J. | PDF | N/A | The interplay between CB2 and NMDA receptors in Parkinsons disease | | 内皮细胞鞘氨醇-1-磷酸受体（S1PR）1，作为人脑血管内皮中的功能性S1PR，限制了小鼠蛛网膜下腔出血后血脑屏障的通透性和神经元损伤。 | Ito, A. | PDF | N/A | Endothelial Sphingosine-1-Phosphate Receptor (S1PR) 1, a Functional S1PR in the Human Cerebrovascular Endothelium, Limits Blood Brain Barrier Permeability and Neuronal Injury following Subarachnoid Hemorrhage in Mice. | | 神经肽能回路对果蝇发育期睡眠的调节 | Hemmi, C. | PDF | N/A | Neuropeptidergic circuit modulation of developmental sleep in Drosophila | | 异质性在执行认知任务的循环网络中的影响多样性 | Santhosh, A. | PDF | N/A | Diversity in the impact of heterogeneities on recurrent networks performing a cognitive task | | 高强度运动在睡前进行，可以增强第二天早晨的记忆编码能力。 | Ramirez Butavand, D. | PDF | N/A | High intensity exercise before sleep boosts memory encoding the next morning | | 通过新型通用接收系统调节白细胞活性 | Tetz, G. | PDF | N/A | Regulating white blood cell activity through the novel Universal Receptive System | | 纤毛病相关蛋白CEP290是视网膜光感受器中纤毛项链和外节膜形成所必需的。 | Moye, A. R. | PDF | N/A | Ciliopathy-associated protein, CEP290, is required for ciliary necklace and outer segment membrane formation in retinal photoreceptors. | | 从长期延时原子力显微镜中量化耻垢分枝杆菌形态的组织和动态 | Soubrier, C. | PDF | N/A | Quantifying the organization and dynamics of M. smegmatis morphology from Long-Term Time-Lapse Atomic Force Microscopy | | 肌动球蛋白和Arp2/3复合物参与纤维素合酶复合物的内化过程。 | Xu, L. | PDF | N/A | Actomyosin and the Arp2/3 Complex Are Involved in the Internalization of Cellulose Synthase Complexes | | 胰腺癌细胞中角蛋白-19的信号肽非依赖性分泌 | Moresco, P. | PDF | N/A | Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells | | 线粒体前体蛋白的伴侣分子招募与保留机制 | Juszkiewicz, S. | PDF | N/A | Mechanism of chaperone recruitment and retention on mitochondrial precursors | | 通过单病毒核糖核蛋白（vRNP）成像技术绘制甲型流感病毒完整感染周期 | Rabouw, H. H. | PDF | N/A | Mapping the complete influenza A virus infection cycle through single vRNP imaging | | N-糖基化作为ATG9A构象和活性决定因素的作用 | Lambrughi, M. | PDF | N/A | Role of N-glycosylation as a determinant of ATG9A conformations and activity | | DNAHX：一种新型、非运动型动力蛋白重链亚家族，通过冷冻电镜内源性鉴定发现 | Chai, P. | PDF | N/A | DNAHX: a novel, non-motile dynein heavy chain subfamily, identified by cryo-EM endogenously | | 以下是这段文字的中文翻译：

证据表明，在苔纲（Marchantiales）单倍体植物谱系中进化出了新的性染色体。

希望这个翻译对你有帮助！如果有其他问题，欢迎继续提问。 | Fu, Y. | PDF | N/A | Evidence for evolution of a new sex chromosome within the Marchantiales haploid plant lineage | | 与布鲁格达综合征相关的基因WT1对SCN5A表达和心脏传导有影响 | Marsman, E. M. J. | PDF | N/A | The Brugada syndrome associated gene WT1 impacts on SCN5A expression and cardiac conduction | | 视网膜血管母细胞瘤中肿瘤诱导血管生成的数学建模与仿真 | Pradelli, F. | PDF | N/A | Mathematical Modeling and Simulation of Tumor-Induced Angiogenesis in Retinal Hemangioblastoma | | 具有极端减振性能的水凝胶中的可调孔隙率 | Day, G. J. | PDF | N/A | Tunable porosity in a hydrogel with extreme vibration damping properties | | 一种用于整合蛋白质功能多模态数据的对抗性方案 | Nasser, R. | PDF | N/A | An adversarial scheme for integrating multi-modal data on protein function | | 利用纳米孔RNA004技术增强大肠杆菌中RNA修饰的检测 | GUO, Z. | PDF | N/A | Enhanced Detection of RNA Modifications in Escherichia coli Utilizing Nanopore RNA004 Technology | | 礁区在整个显生宙期间都是生物多样性的热点区域。 | Close, R. A. | PDF | N/A | Reefal regions were biodiversity hotspots throughout the Phanerozoic | | 甲状腺功能减退小鼠心脏中的代谢变化——来自非靶向代谢组学的见解 | Guan, H. | PDF | N/A | Metabolic shifts in the heart of hypothyroid mice -- insights from untargeted metabolomics | | N,N-二甲基乙酰胺能够阻断炎症引发的早产，并改善母体系统性免疫反应。 | Reznik, S. | PDF | N/A | N,N-dimethylacetamide blocks inflammation-induced preterm birth and remediates maternal systemic immune responses | | 提高N,N-二甲基乙酰胺（DMA）作为早产潜在治疗手段的安全性：在孕鼠模型中使用阴道纳米制剂的研究 | Mir, A. | PDF | N/A | Improving the Safety of N,N-Dimethylacetamide (DMA) as a Potential Treatment for Preterm Birth in a Pregnant Mouse Model Using a Vaginal Nanoformulation | | VDR-钙轴调节断奶期间由饮食驱动的代谢转变 | Jawla, N. | PDF | N/A | VDR-calcium axis regulates the diet-driven metabolic shift during weaning | | OsWRKY53通过精细调控PEP和PSK介导的信号传导之间的相互作用，决定了水稻的伤口反应。 | Harshith, C. Y. | PDF | N/A | OsWRKY53 dictates wound responses in rice through fine-tuning cross-talk between PEP and PSK mediated signalling | | 作物基因型调节与根腐病抗性相关的微生物群落组成及关键类群的丰度 | Gfeller, V. | PDF | N/A | Crop genotype modulates root rot resistance-associated microbial community composition and abundance of key taxa | | 光合调节在受控的室内农业设置中，通过动态变化的照明维持生菜的生长。 | Makinen, A. | PDF | N/A | Photosynthetic adjustments maintain lettuce growth under dynamically changing lighting in controlled indoor farming setups | | 使用SED-ML进行可重复的模型管理：验证BioModels在多个模拟引擎中的一致性 | Smith, L. P. | PDF | N/A | Using SED-ML for reproducible curation: Verifying BioModels across multiple simulation engines | | 多种神经网络方法，包括拓扑数据分析的应用，增强了根据处理条件对人类诱导多能干细胞集落进行分类的能力。 | Ruys de Perez, A. | PDF | N/A | Multiple neural network approaches, including use of topological data analysis, enhances classification of human induced pluripotent stem cell colonies by treatment condition | | 棕色脂肪组织中的胚胎巨噬细胞在空间上与发育中的神经相关联。 | Felix, I. | PDF | N/A | Embryonic macrophages in brown adipose tissue are spatially associated with developing nerves | | scTFBridge：一种基于TF-基序结合的分离深度生成模型，用于单细胞多组学中的基因调控推断 | Wang, F.-a. | PDF | N/A | scTFBridge: A Disentangled Deep Generative Model Informed by TF-Motif Binding for Gene Regulation Inference in Single-Cell Multi-Omics | | 通过复杂马尔可夫网络分析揭示的端粒G-四链体中间体。 | Sainz-Agost, A. | PDF | N/A | Telomeric G-quadruplex Intermediates unveiled by Complex Markov Network Analysis. | | SARS-CoV-2中和抗体的特异性在近期感染的婴儿和免疫印记个体之间存在显著差异。 | Dadonaite, B. | PDF | N/A | SARS-CoV-2 neutralizing antibody specificities differ dramatically between recently infected infants and immune-imprinted individuals | | 评估病毒对紫外线、臭氧和游离氯异质性敏感性的统计框架 | Yanagihara, M. | PDF | N/A | Statistical framework for assessing heterogeneous sensitivity of viruses to ultraviolet, ozone, and free chlorine | | 一种新型的血红素降解酶，它在调节血红素和铁稳态中起关键作用，并促进粪肠球菌的毒力增强 | Lemos, J. A. | PDF | N/A | A Novel Heme-Degrading Enzyme that Regulates Heme and Iron Homeostasis and Promotes Virulence in Enterococcus faecalis | | 伤寒沙门氏菌和甲型副伤寒沙门氏菌对血清抗体和补体的逃避 | Guerra, F. E. | PDF | N/A | Evasion of serum antibodies and complement by Salmonella Typhi and Paratyphi A | | GacA调控共生并介导假单胞菌生活方式转变 | Luo, Y. | PDF | N/A | GacA regulates symbiosis and mediates lifestyle transitions in Pseudomonas | | 优化原代人脾成纤维细胞的转染效率 | Kaur, A. | PDF | N/A | Optimizing Transfection Efficiency in Primary Human Splenic Fibroblast Cells | | ATAC-seq作为一种多功能工具，用于描绘基因组和表观基因组 | Toumi, I. | PDF | N/A | ATAC-seq as a versatile tool to portray genomes and epigenomes | | THAP9在少突胶质细胞发育阶段中的转录景观：分子机制与网络分析 | Bhardwaj, T. | PDF | N/A | Transcriptional Landscape of THAP9 across Oligodendrocyte Developmental Stages: Molecular Mechanisms and Network Analysis | | 模块化DNA条形码标记纳米抗体实现多重原位蛋白质成像和高通量生物分子检测 | Zhong, S. | PDF | N/A | Modular DNA Barcoding of Nanobodies Enables Multiplexed in situ Protein Imaging and High-throughput Biomolecule Detection | | GALILEO通过生成式方法扩展化学空间，并以高命中率实现了一次性识别出一系列新型、特异性、下一代广谱抗病毒化合物的库。 | Umansky, T. | PDF | N/A | GALILEO Generatively Expands Chemical Space and Achieves One-Shot Identification of a Library of Novel, Specific, Next Generation Broad-Spectrum Antiviral Compounds at High Hit Rates | | 一种系统发育方法识别了SARS-CoV-2突变谱演化的候选驱动因素 | Corbett-Detig, R. | PDF | N/A | A phylogenetic method identifies candidate drivers of the evolution of the SARS-CoV-2 mutation spectrum |

BioRxiv 2025-01-19 Papers

标题	作者	PDF链接	代码仓库	Title
实验室小鼠的视频表型分析平台	Choudhary, A.	PDF	N/A	Video based phenotyping platform for the laboratory mouse
线粒体自噬受体BNIP3L/Nix协调核钙信号以调节肌肉表型。	Field, J. T.	PDF	N/A	The mitophagy receptor BNIP3L/Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
增强型双重稳健后插补推断在蛋白质组学数据中的应用	Moon, H.	PDF	N/A	Augmented Doubly Robust Post-Imputation Inference for Proteomic data
冷冻电镜引导的查加斯病疫苗候选物TcPOP开放和封闭构象的分析及其抗体反应特征研究	Batra, S.	PDF	N/A	Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation
传粉者对当地和景观草地特征的响应存在差异	Lichtenberg, E. M.	PDF	N/A	Pollinators differentially respond to local and landscape grassland features
海百合基于视蛋白的光感受：对Antedon bifida的分子与行为研究	Nonclercq, Y.	PDF	N/A	Opsin-based photoreception in Crinoids: a molecular and behavioural study of Antedon bifida
自组织的噬菌体与宿主菌落群体的共存	Yadav, A.	PDF	N/A	Self-organized coexistence of phage and a population of host colonies
MLPA：一种用于个性化癌症模拟与治疗优化的多尺度数字孪生框架	Chen, J. Y.	PDF	N/A	MLPA: A Multi-scale Digital Twin Framework for Personalized Cancer Simulation and Treatment Optimization
使用镜像正向遗传学方法鉴定作用于核非编码RNA的人类通路	Che, R.	PDF	N/A	Identification of Human Pathways Acting on Nuclear Non-Coding RNAs Using the Mirror Forward Genetic Approach
传统经颅直流电刺激（tDCS）与高清晰度经颅直流电刺激（HD-tDCS）对小脑的偏移镇痛效果差异	O'Connor, N.	PDF	N/A	Differential effects of conventional transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) of the cerebellum on offset analgesia
实时预测和相位靶向脑振荡	Jongejan, S. L.	PDF	N/A	Predicting and phase targeting brain oscillations in real-time
前扣带皮层中用于信息和努力选择的常见持续目标机制	Gonzalez, V. V.	PDF	N/A	A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices
优势逆转在时间变化的环境中维持了大效应抗性多态性。	Karageorgi, M.	PDF	N/A	Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments
解码肝癌预后：从多组学亚型、预后模型到单细胞验证	Wang, Y.	PDF	N/A	Decoding Liver Cancer Prognosis: From Multi-omics Subtypes, Prognostic Models to Single Cell Validation
大脑特征图揭示了腹侧流中逐步发展的动物特征表征。	Zhang, Z.	PDF	N/A	Brain Feature Maps Reveal Progressive Animal-Feature Representations in the Ventral Stream.
蚂蚁根据过去、即将发生和预测的逆境进行适应性决策	Notomi, Y.	PDF	N/A	Adaptive decision-making by ants in response to past, imminent, and predicted adversity
DNA甲基化影响大肠杆菌中的基因表达，但不影响其全局染色质结构。	Morgan, W. J.	PDF	N/A	DNA methylation affects gene expression but not global chromatin structure in Escherichia coli
通过冷冻电镜和分子动力学模拟揭示的血管紧张素-I转换酶的二聚化和动力学	mancl, j. M.	PDF	N/A	Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations
由微外显子跳跃定义的神经元细胞粘附分子（NRCAM）变体是高级别胶质瘤中一种重要的、抗原性独特的且可靶向的蛋白质形式。	Sehgal, P.	PDF	N/A	Neuronal cell adhesion molecule (NRCAM) variant defined by microexon skipping is an essential, antigenically distinct, and targetable proteoform in high-grade glioma
SFCalculator：连接深度生成模型与晶体学	Li, M.	PDF	N/A	SFCalculator: connecting deep generative models and crystallography
拥挤效应和序列依赖在视觉感知中的相互影响	Cass, J.	PDF	N/A	Reciprocal roles of crowding and serial dependence on visual perception
UFMylation与核糖体相关质量控制途径的协同作用清除了内质网上停滞的新生链。	Mihailovic, M.	PDF	N/A	The coordinated action of UFMylation and ribosome-associated quality control pathway clears arrested nascent chains at the endoplasmic reticulum
在一项关于滤食性两栖动物的研究中发现，微塑料暴露对其生长产生了负面影响，但并未显著影响皮质酮水平、氧化应激或端粒长度。	Martin, C. A.	PDF	N/A	Growth but not corticosterone, oxidative stress or telomere length is negatively affected by microplastic exposure in a filter-feeding amphibian
霉菌毒素白僵菌素是组织蛋白酶B的非竞争性抑制剂。	Yang, X.	PDF	N/A	The mycotoxin Beauvericin is an uncompetitive inhibitor of Cathepsin B
B4GALNT1在神经节苷脂合成中的构象动力学与膜插入机制	Welland, J. W. J.	PDF	N/A	Conformational Dynamics and Membrane Insertion Mechanism of B4GALNT1 in Ganglioside Synthesis
荧光寿命成像显微镜用于三阴性乳腺癌中LDHB抑制的代谢分析	Galloway, A. E.	PDF	N/A	Fluorescence lifetime imaging microscopy for metabolic analysis of LDHB inhibition in triple negative breast cancer
诱导极化在药物发现应用中的作用	Mohamed, A.	PDF	N/A	The role of induced polarization in drug discovery applications
使用对比学习和领域对抗学习对细胞涂片数据进行三重效应校正	Yan, C.	PDF	N/A	Triple-effect correction for Cell Painting data with contrastive and domain-adversarial learning
轴突中ATP运输的建模：自发性神经元放电和通过隧道纳米管的线粒体转移的影响	Kuznetsov, A. V.	PDF	N/A	Modeling of ATP Transport in an Axon: Effects of Spontaneous Neuron Firing and Mitochondrial Transfer via Tunneling Nanotubes
胰腺导管腺癌基质亚型与神经侵袭关系的转录组学分析	Yildizhan, S. E.	PDF	N/A	Transcriptomic Analysis Of The Relationship Between Pancreatic Ductal Adenocarcinoma Stromal Subtypes And Neural Invasion
女性自发性高血压大鼠冠状动脉微血管功能障碍（CMD）的动物模型：饮食的作用	Najjar, R. S.	PDF	N/A	An animal model of coronary microvascular dysfunction (CMD) in the female spontaneously hypertensive rat: the role of diet
造血衰老的三个表型特征的独特原因	Chia, J. J.	PDF	N/A	Distinct causes of three phenotypic hallmarks of hematopoietic aging
通过CRISPR-Cas9技术敲除干扰素受体，研究大西洋鲑鱼细胞中的抗病毒通路。	Reza, M. A. N.	PDF	N/A	Investigating antiviral pathways in Atlantic salmon cells through interferon receptor knockouts via CRISPR-Cas9
用于研究核小体重定位的天然核小体定位元件	Chen, R.-W.	PDF	N/A	Native nucleosome-positioning elements for the investigation of nucleosome repositioning
KIDINS220和InsP8确保了磷酸盐输出蛋白XPR1的逐步调控。	Wang, X.	PDF	N/A	KIDINS220 and InsP8 safeguard the stepwise regulation of phosphate exporter XPR1
解密微小隐孢子虫中的转录过程：多顺反子基因表达与染色质可及性	Xiao, R.	PDF	N/A	Deciphering Transcription in Cryptosporidium parvum: Polycistronic Gene Expression and Chromatin Accessibility
关于胰腺细胞中CFTR基因顺式调控的新见解	Blotas, C.	PDF	N/A	New insights into the cis-regulation of the CFTR gene in pancreatic cells
热循环转录提高了RNA的产量。	Liu, Y.	PDF	N/A	Thermal cycling transcription boosts RNA production.
VitisC：通过细胞骨架集成支架可视化感兴趣的目标	Yin, B.	PDF	N/A	VitisC: Visualizing interested target via integrated scaffold of cytoophidium
脂质锥超家族：脂质、肽聚糖和胞外多糖代谢、生物间冲突与免疫的统一主题	Burroughs, A. M.	PDF	N/A	The Lipocone Superfamily: A Unifying Theme In Metabolism Of Lipids, Peptidoglycan And Exopolysaccharides, Inter-Organismal Conflicts And Immunity
BK通道的内在开放源于疏水门控中的固有泄漏	Jia, Z.	PDF	N/A	Intrinsic Opening of BK Channels Derives from Inherent Leakage in Hydrophobic Gating
微滴中的数字噬菌体生物学	Givelet, L.	PDF	N/A	Digital Phage Biology in Droplets
启用xMAS构建器对复杂弯曲细胞膜进行原子级建模与仿真	Trebesch, N.	PDF	N/A	Enabling Atomistic Modeling and Simulation of Complex Curved Cellular Membranes with xMAS Builder
HPV阴性头颈鳞状细胞癌（HPV- HNSCC）中外周和肿瘤浸润免疫细胞的单细胞景观	Galvani, R. G. A.	PDF	N/A	The Single-Cell Landscape of Peripheral and Tumor-infiltrating Immune Cells in HPV- HNSCC
导管内乳头状黏液性肿瘤的细胞可塑性与重复元件失调相关	Pankaj, A.	PDF	N/A	Intraductal Papillary Mucinous Neoplasm Cellular Plasticity linked with Repeat Element Dysregulation
H3K27me3和PRC1-H2AK119ub通路在H3K9甲基化缺失后协同维持异染色质和转录沉默。	Fukuda, K.	PDF	N/A	H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation
周期性障碍调节膜张力传播以实现局部机械转导	Catala, F.	PDF	N/A	Periodic Obstacles Regulate Membrane Tension Propagation to Enable Localized Mechanotransduction
一种新颖的优化硝酸银染色方法用于可视化骨细胞陷窝-小管系统	Wu, J.	PDF	N/A	A Novel Optimized Silver Nitrate Staining Method for Visualizing the Osteocyte Lacuno-Canalicular System
在系统性硬化症中绘制空间分辨转录组图谱	Li, Z.	PDF	N/A	Mapping spatially-resolved transcriptomes in systemic sclerosis
以下是这段英文的中文翻译：

黄曲霉（Aspergillus flavus）着丝粒和亚端粒染色体区域中串联反向重复序列的聚类

翻译说明： - Clustering 翻译为“聚类”，表示某种模式或结构的集中分布。 - Tandem Inverse Duplications 翻译为“串联反向重复序列”，指的是基因组中重复出现的序列，且方向相反。 - Centromeric and Subtelomeric Chromosomal Regions 翻译为“着丝粒和亚端粒染色体区域”，分别指染色体中靠近着丝粒和端粒的区域。 - Aspergillus flavus 是“黄曲霉”的学名，是一种常见的真菌。

一种用于多重诊断中高效分离血浆的纸-液滴混合系统

这段翻译将英文标题“Comparing the Seasonal Diets of Buff-tailed Bumblebees and Honey Bees in a Forest Landscape: A Metabarcoding Approach”转化为中文，同时保持了原文的学术性和专业性。翻译中，“Buff-tailed Bumblebees”译为“黄尾熊蜂”，“Honey Bees”译为“蜜蜂”，“Forest Landscape”译为“森林景观”，“Seasonal Diets”译为“季节性饮食”，而“Metabarcoding Approach”则译为“元条形码技术”，这些都是生物学和生态学领域常用的术语。整个标题的翻译旨在准确传达原文的研究内容和采用的方法。 | Gay, C. | PDF | N/A | Comparing the Seasonal Diets of Buff-tailed Bumblebees and Honey Bees in a Forest Landscape: A Metabarcoding Approach | | 鼹鼠蟋蟀的多种运动步态 | Yuval, O. | PDF | N/A | Multiple locomotion gaits in the mole cricket | | DiffHiChIP：从HiChIP数据中识别差异染色质接触 | Bhattacharyya, S. | PDF | N/A | DiffHiChIP: Identifying differential chromatin contacts from HiChIP data | | MetaLigand：一个用于预测非肽配体介导的细胞间通讯的数据库 | Xin, Y. | PDF | N/A | MetaLigand: A database for predicting non-peptide ligand mediated cell-cell communication | | 右前额叶下皮层在共情物理疼痛和社会疼痛中的因果性和可分离性作用 | De Lillo, M. | PDF | N/A | A Causal and Dissociable Role for the Right Inferior Prefrontal Cortex in Empathy for Physical and Social Pain | | 社交视觉的共享与个体调谐曲线 | Varrier, R. S. | PDF | N/A | Shared and individual tuning curves for social vision | | NMDA谷氨酸受体介导的海马可塑性与记忆的转录和突触调控 | Parra-Damas, A. | PDF | N/A | Transcriptional and synaptic regulation of NMDA glutamate receptor-mediated hippocampal plasticity and memory | | 阐述大鼠闭环前脑回路的连接：在皮质-纹状体-苍白球三重下行投射中，与丘脑反馈至前外侧下丘脑区域的新地形学证据的限定性研究。 | Negishi, K. | PDF | N/A | Elaborating the connections of a closed-loop forebrain circuit in the rat: Circumscribed evidence for novel topography within a cortico-striato-pallidal triple descending projection, with thalamic feedback, to the anterior lateral hypothalamic area | | Takens定理用于评估脑电图（EEG）轨迹：大脑动力学的区域变化 | Tozzi, A. | PDF | N/A | Takens' theorem to assess EEG traces: regional variations in brain dynamics | | 整合性基因共表达网络分析揭示了与阿尔茨海默病病理相关的蛋白质编码基因和长链非编码RNA基因 | Zebardast, F. | PDF | N/A | Integrative Gene Co-expression Network Analysis Reveals Protein-Coding and lncRNA Genes Associated with Alzheimer's Disease Pathology | | 持续的干扰素信号传导导致关节炎中的感觉神经元可塑性和疼痛。 | Su, J. | PDF | N/A | Persistent interferon signaling that causes sensory neuron plasticity and pain in arthritis | | 单细胞分辨率的空间免疫组库揭示了人类免疫疾病中淋巴聚集体的空间异质性。 | Zhan, X. | PDF | N/A | Single cell resolved spatial immune repertoire unveils spatial heterogeneity of lymphoid aggregates in human immune disorders | | 系统性评估微环境依赖性转录模式及细胞间通讯 | Pareja-Lorente, E. | PDF | N/A | Systematic assessment of microenvironment-dependent transcriptional patterns and intercellular communication | | 深情凝视：心脏传入信号与迷走神经张力对视知觉的影响 | Lin, Y. | PDF | N/A | Heartfelt gaze: Cardiac afferent signals and vagal tone affect gaze perception | | 钙/钙调蛋白响应激酶II（CaMKII）枢纽域中的变构因子决定了GHB配体对CaMKIIa的选择性。 | Gauger, S. J. | PDF | N/A | Allosteric factors in the calcium/calmodulin-responsive kinase II hub domain determine selectivity of GHB ligands for CaMKIIa | | 基于靶标的环肽结合剂从头设计 | Wang, F. | PDF | N/A | Target-based de novo design of cyclic peptide binders | | BIND：通过知识图谱驱动的机器学习进行大规模生物交互网络发现 | Aamer, N. | PDF | N/A | BIND: Large-Scale Biological Interaction Network Discovery through Knowledge Graph-Driven Machine Learning | | IV型多药ABC转运蛋白中核苷酸和底物结合位点之间的双向通讯 | Perez Carrillo, V. H. | PDF | N/A | Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter | | 关于鞘磷脂纳米乳剂作为非小细胞肺癌治疗药物递送系统的机制研究 | Ramos Docampo, E. | PDF | N/A | Mechanistic Insights into Sphingomyelin Nanoemulsions as Drug Delivery Systems for Non-Small Cell Lung Cancer Therapy | | 基因语法定义了超螺旋介导的转录反馈 | Johnstone, C. P. | PDF | N/A | Gene syntax defines supercoiling-mediated transcriptional feedback | | IL-27在感染期间限制造血干细胞和祖细胞（HSPC）的分化，并防止干细胞耗竭。 | Aldridge, D. L. | PDF | N/A | IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion | | 一种新型COE-D8-磷霉素共轭物有效对抗一线抗生素耐药性尿路致病性大肠杆菌 | Ruan, L. | PDF | N/A | A Novel COE-D8-Fosfomycin Conjugate Effectively Against First-line Antibiotic Resistant Uropathogenic Escherichia coli | | 毒力调节因子bvgS是鸟博德特氏菌(Bordetella avium)在营养诱导下形成丝状体所必需的。 | Perslow, N. G. | PDF | N/A | The virulence regulator bvgS is required for nutrient-induced filamentation in Bordetella avium | | 与共受体使用相关的HIV-1包膜糖蛋白gp120和反义蛋白ASP中氨基酸替换的共变异 | Pavesi, A. | PDF | N/A | Covariation of amino acid substitutions in the HIV-1 envelope glycoprotein gp120 and the antisense protein ASP associated with coreceptor usage | | 缺乏RNase HI会影响肠炎沙门氏菌的毒力。 | Jimenez-Espadafor, J. | PDF | N/A | Lack of RNase HI affects virulence in Salmonella enterica | | 在为期3周的微重力模拟人体研究中，p53网络衰老相关基因的表达受到“摇动而非搅拌”的影响。

一个简单的年龄结构、温度依赖的褐飞虱（Nilaparvata lugens (Stal)）种群增长模型

翻译说明： 1. "simple" 翻译为 "简单的" 2. "age-structured" 翻译为 "年龄结构的" 3. "temperature-dependent" 翻译为 "温度依赖的" 4. "population growth model" 翻译为 "种群增长模型" 5. "brown rice hopper" 翻译为 "褐飞虱" 6. "Nilaparvata lugens (Stal)" 是褐飞虱的学名，保留原文

BioRxiv 2025-01-18 Papers

标题	作者	PDF链接	代码仓库	Title
关于全基因组关联研究中表型的遗传起源：用于探索仅加性等位基因效应或加性与非加性等位基因效应的SNP分配估计遗传力工具（SAFE-h2）

在现代遗传学研究中，全基因组关联研究（GWAS）已成为揭示复杂性状遗传基础的重要方法。然而，理解表型变异的遗传起源仍然是一个挑战。本文介绍了一种名为SNP分配估计遗传力工具（SAFE-h2）的新方法，旨在探索仅加性等位基因效应或加性与非加性等位基因效应对表型的影响。

SAFE-h2工具通过分析单核苷酸多态性（SNP）的分配，帮助研究人员更准确地估计遗传力。遗传力是指遗传因素在表型变异中所占的比例，通常分为加性遗传力和非加性遗传力。加性遗传力主要反映等位基因的简单累加效应，而非加性遗传力则涉及等位基因之间的相互作用，如显性和上位效应。

使用SAFE-h2工具，研究人员可以区分和量化这些不同类型的遗传效应，从而更全面地理解复杂性状的遗传结构。这不仅有助于揭示疾病的遗传基础，还能为个性化医疗和精准农业提供重要的遗传信息。

通过聚乙烯醇水凝胶珠固定的集胞藻PCC 6803实现持续异丁烯生产

翻译说明： - "Sustained" 翻译为“持续的”。 - "Isobutene" 是“异丁烯”，一种有机化合物。 - "Synechocystis sp. PCC 6803" 是一种蓝藻（集胞藻），PCC 6803 是其菌株编号。 - "Entrapped" 翻译为“固定的”或“包埋的”。 - "Polyvinyl Alcohol Hydrogel Beads" 是“聚乙烯醇水凝胶珠”，一种常用于固定微生物的材料。

希望这对你有帮助！ | Vajravel, S. | PDF | N/A | Sustained Isobutene Production by Synechocystis sp. PCC 6803 Entrapped in Polyvinyl Alcohol Hydrogel Beads | | 基于结构的发现：具有强效体内疗效的高生物利用度、共价、广谱冠状病毒-MPro抑制剂 | Detomasi, T. C. | PDF | N/A | Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus-MPro inhibitors with potent in vivo efficacy | | 利用细胞外囊泡在巨噬细胞免疫调节中实现稳定且功能性IL-10的递送 | Saleh, N. A. | PDF | N/A | Harnessing Extracellular Vesicles for Stabilized and Functional IL-10 Delivery in Macrophage Immunomodulation | | IL-21-STAT3轴负向调控B细胞中LAIR1的表达。 | Yoshida, K. | PDF | N/A | IL-21-STAT3 axis negatively regulates LAIR1 expression in B cells | | 新兴的真菌病原体耳念珠菌（Candida auris）通过诱导IFNγ来定殖于哺乳动物的毛囊。 | Merrill, E. D. | PDF | N/A | The emerging fungal pathogen Candida auris induces IFNγ to colonize mammalian hair follicles | | 炎症性疾病微生物组共享由C反应蛋白预测的功能性致病性。 | Britton, G. J. | PDF | N/A | Inflammatory disease microbiomes share a functional pathogenicity predicted by C-reactive protein | | 数据驱动的复杂微生物组中全面基因表达分析工作流程 | Mameda, R. | PDF | N/A | Data-driven workflow for comprehensive gene expression analysis in complex microbiomes | | 对蛋白质序列和结构的综合分析重新定义了病毒多样性以及黄病毒科的分类学。 | Simmonds, P. | PDF | N/A | Integrated analysis of protein sequence and structureredefines viral diversity and the taxonomy of the Flaviviridae | | 细菌在植物定殖中的适应性受植物生长基质的影响 | Torres, M. | PDF | N/A | Bacterial fitness for plant colonization is influenced by plant growth substrate | | 淋球菌聚集导致与抗生素耐受性相关的基因上调。 | Kraus-Roemer, S. | PDF | N/A | Gonococcal aggregation causes upregulation of genes involved in antibiotic tolerance | | 项目ArHa：生产一种沙粒病毒和汉坦病毒宿主-病原体数据库的协议。 | Simons, D. | PDF | N/A | Protocol for the production of an Arenavirus and Hantavirus host-pathogen database: Project ArHa. | | 系统性确定结构编辑对分枝杆菌积累的影响 | Dash, R. | PDF | N/A | Systematic Determination of the Impact of Structural Edits on Accumulation into Mycobacteria | | 感染巨噬细胞的定量蛋白质组学揭示了新型利什曼原虫毒力因子 | Hagedorn, N. | PDF | N/A | Quantitative proteomics of infected macrophages reveals novel Leishmania virulence factors | | 关于XIAP缺陷患者中尽管存在暴发性爱泼斯坦-巴尔病毒感染却未出现淋巴瘤的见解 | Sun, Y. | PDF | N/A | Insights into the Absence of Lymphoma Despite Fulminant Epstein-Barr Virus Infection in Patients with XIAP Deficiency | | 含有唾液酸的糖脂扩展了肠病毒D68的受体库。 | Pereirinha da Silva, A. K. | PDF | N/A | Sialic acid-containing glycolipids extend the receptor repertoire of Enterovirus-D68 | | 植物生长促进真菌内生菌Colletotrichum tofieldiae Ct0861减少了玉米粒中产霉菌毒素的曲霉菌 | Diaz-Gonzalez, S. | PDF | N/A | Plant Growth Promoting fungal endophyte Colletotrichum tofieldiae Ct0861 reduces mycotoxigenic Aspergillus fungi in maize grains | | 肺结核中宿主免疫相关基因的表观遗传调控：外周血单个核细胞DNA甲基化谱的综合分析 | Kumar, A. | PDF | N/A | Epigenetic Modulation of Host Immunity related genes in Pulmonary Tuberculosis: A Comprehensive Analysis of DNA Methylation Profiles in Peripheral Blood Mononuclear Cells | | 对37种堆肥的综合分析：三种植物-病原体系统中土传病害抑制的微生物指标 | Logo, A. | PDF | N/A | Comprehensive analysis of 37 composts: microbial indicators for soilborne disease suppression in three plant-pathogen systems | | 基于测序的空间转录组学与单细胞RNA测序灵敏度 | Liao, R. | PDF | N/A | Sequencing-based Spatial Transcriptomics with scRNA-seq Sensitivity | | 使用综合分割技术扩展细胞冷冻电子断层扫描数据分析 | Last, M. G. F. | PDF | N/A | Scaling data analyses in cellular cryoET using comprehensive segmentation | | 肠道细菌中不同类别的钼依赖酶产生尿石素 | Bae, M. | PDF | N/A | Distinct Classes of Gut Bacterial Molybdenum-Dependent Enzymes Produce Urolithins | | 利用高通量微流控平台量化蛋白质解折叠动力学 | Atsavapranee, B. | PDF | N/A | Quantifying protein unfolding kinetics with a high-throughput microfluidic platform | | 细胞内运输途径的时空微环境映射（microMap）：细胞穿透肽跨越血脑屏障的研究 | Morgan, D. C. | PDF | N/A | Temporal Microenvironment Mapping (microMap) of Intracellular Trafficking Pathways of Cell-Penetrating Peptides Across the Blood-Brain Barrier | | 糖基化身：用于研究癌症-免疫细胞相互作用组的珠涂层膜模型 | Miranda, A. | PDF | N/A | GlycoAvatars: Bead-Coated Membrane Models for Studying the Cancer-Immune Cells Interactome | | 糖基化身：用于研究癌症-免疫细胞相互作用组的珠涂层膜模型 | Miranda, A. | PDF | N/A | GlycoAvatars: Bead-Coated Membrane Models for Studying the Cancer-Immune Cells Interactome | | 高产生物生产无病毒P4-EKORhE多重溶菌转导颗粒作为抗菌基因治疗剂 | Ramirez-Garcia, R. | PDF | N/A | High-yield bioproduction of virus-free P4-EKORhE multi-lysin transducing particles as an antimicrobial gene therapeutic | | 基于新型荧光报告基因的高通量分泌蛋白测定方法揭示了沙门氏菌三型分泌系统的调控与结构特征 | Leach, S. A. | PDF | N/A | A High Throughput Assay for Measuring Secreted Protein Based on a de novo Fluorescent Reporter Reveals Regulatory and Structural Insights in Salmonella Type Three Secretion System | | 曼氏血吸虫抗原诱导的先天免疫记忆特征表现为线粒体生物发生，并且可以被卵巢产生的激素所抑制。 | Oviedo, J. M. | PDF | N/A | Schistosoma mansoni antigen induced innate immune memory features mitochondrial biogenesis and can be inhibited by ovarian produced hormones | | 戊糖片球菌（Pediococcus pentosaceus）能够减少α-突触核蛋白的积累，并在秀丽隐杆线虫（Caenorhabditis elegans）和青鳉鱼（Oryzias latipes）中缓解帕金森症状。 | Komura, T. | PDF | N/A | Pediococcus pentosaceus decreases α-synuclein accumulation and alleviates parkinsonism in Caenorhabditis elegans and Oryzias latipes | | 识别与鲍曼不动杆菌高水平粘菌素抗性相关的进化权衡 | Acharya, K. | PDF | N/A | Identification of Evolutionary Trade-Offs Associated with High-Level Colistin Resistance in Acinetobacter baumannii | | 白色念珠菌通过p38-MAPK和HIF-1α途径以及代谢重编程增强黑色素瘤细胞的侵袭性 | Aparicio-Fernandez, L. | PDF | N/A | Candida albicans enhances melanoma cell aggressiveness through p38-MAPK and HIF-1α pathways and metabolic reprogramming | | 传染性法氏囊病病毒（IBDV）VP3的C端编码一个预测的内在无序区域（IDR），该区域促进细胞质斑点的形成并调节其物理特性。 | Brodrick, A. J. | PDF | N/A | The C terminus of infectious bursal disease virus (IBDV) VP3 encodes a predicted intrinsically disordered region (IDR), which promotes the formation of cytoplasmic puncta and modulates their physical properties. | | AMPKa2/PHF2轴在肌肉干细胞命运转变过程中对脂滴的代谢至关重要。 | Cicciarello, D. | PDF | N/A | The AMPKa2/PHF2 axis is critical for turning over lipid droplets during muscle stem cell fate | | 线粒体Ca2+在内质网（ER）-线粒体接触位点上闪烁，以抑制储存操作的Ca2+进入。 | Lin, Y.-C. | PDF | N/A | Mitochondrial Ca2+ flickers on endoplasmic reticulum (ER)-mitochondrial contact sites to suppress store-operated Ca2+ entry | | 升高的SUN1通过机械性将微管与核纤层耦合，促进与衰老相关的极性缺陷。 | Li, Y. | PDF | N/A | Elevated SUN1 promotes aging-related polarity defects through mechanical coupling microtubules to the nuclear lamina | | UFMylation与核糖体相关质量控制途径的协同作用清除了在内质网处停滞的新生链。 | Mihailovic, M. | PDF | N/A | The coordinated action of UFMylation and ribosome-associated quality control pathway clears arrested nascent chains at the endoplasmic reticulum | | 使用T细胞中的邻近标记技术鉴定新型Kv1.3通道相互作用蛋白 | Kour, D. | PDF | N/A | Identification of novel Kv1.3 channel-interacting proteins using proximity labelling in T-cells | | 具有多功能读出和紧凑尺寸的基因编码机械传感器 | Ren, Y. | PDF | N/A | Genetically encoded mechano-sensors with versatile readouts and compact size | | LARP6在肝纤维化中调节纤维化基因的mRNA翻译 | Kim, H. Y. | PDF | N/A | LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis | | 三者的力量：动力蛋白复合体在负载下与三个动力蛋白结合，以产生更大的力量 | Rao, L. | PDF | N/A | The Power of Three: Dynactin associates with three dyneins under load for greater force production | | 双头结合状态驱动KIF1A的超持续性 | Rao, L. | PDF | N/A | A Two-Heads-Bound State Drives KIF1A Superprocessivity | | 鲍德温效应重装上阵：中等水平的表型可塑性有利于进化拯救 | Lambert, A. | PDF | N/A | The Baldwin effect reloaded: Intermediate levels of phenotypic plasticity favor evolutionary rescue | | 新的深分支环境质体基因组在藻类生命树上 | Jamy, M. | PDF | N/A | New deep-branching environmental plastid genomes on the algal tree of life | | 基于变分自编码器的模型提升了血细胞性状的多基因预测能力 | Li, X. | PDF | N/A | Variational Autoencoder-based Model Improves Polygenic Prediction in Blood Cell Traits | | 差异调控脑特异性分子通路是姜黄素在成年期特定阶段对多巴胺能神经元具有保护作用的原因：来自帕金森病ALSS果蝇模型的见解 | Das, A. | PDF | N/A | Differential regulation of brain-specific molecular pathways is the reason for curcumin adult life-phase specific DAergic neuroprotection: Insights from ALSS Drosophila model of Parkinson disease | | 出生后减少D1-SPNs中eIF4E的过度表达可改善KCNQ功能障碍、过度兴奋和自闭症谱系障碍（ASD）样行为。 | Aaltonen, A. | PDF | N/A | Postnatal reduction of eIF4E overexpression in D1-SPNs ameliorates KCNQ dysfunction, hyperexcitability and ASD-like behaviours. | | 新生儿丘脑在发育过程中的功能组织通过功能性磁共振成像（fMRI）描绘 | Kebiri, H. | PDF | N/A | Functional organization of the neonatal thalamus across development depicted by functional MRI | | 同步进行的脑电图-正电子发射断层扫描-磁共振成像（EEG-PET-MRI）技术揭示了在清醒和快速眼动睡眠（NREM）期间，血流动力学和代谢动态在时间和空间上的耦合关系及其结构化特征。 | Chen, J. E. | PDF | N/A | Simultaneous EEG-PET-MRI identifies temporally coupled, spatially structured hemodynamic and metabolic dynamics across wakefulness and NREM sleep | | 部分Wwox功能丧失会增加小鼠败血症和神经炎症的严重程度 | De La Cruz, P. | PDF | N/A | Partial Wwox Loss of Function Increases Severity of Murine Sepsis and Neuroinflammation | | circAβ-a RNA编码的Aβ175——散发性阿尔茨海默病中β-淀粉样斑块形成和沉积的潜在驱动因素。 | Mo, D. | PDF | N/A | circAβ-a RNA encoded Aβ175--the hidden driver of β-amyloid plaque formation and deposition in sporadic Alzheimer's disease. | | 电刺激调节增强功能性神经重连在小鼠神经移植模型中治疗慢性脊髓损伤的效果 | Jara, J. S. | PDF | N/A | Conditioning electrical stimulation enhances functional rewiring in a mouse model of nerve transfer to treat chronic spinal cord injury | | 芬太尼阻断钾离子通道导致木僵胸综合征 | Wei, A. D. | PDF | N/A | Fentanyl blockade of K+ channels contribute to Wooden Chest Syndrome | | 缺氧诱导因子1保护神经元免受Sarm1介导的神经退行性变的影响。 | Meraner, P. | PDF | N/A | Hypoxia-inducible factor 1 protects neurons from Sarm1-mediated neurodegeneration | | 前额叶皮层中通过异聚型烟碱受体对吊灯样细胞的胆碱能调节 | Martinez-Marquez, E. | PDF | N/A | Cholinergic Modulation of Chandelier Cells via Heteromeric Nicotinic Receptors in Prefrontal Cortex | | PD-1在胸腺CD8+ T细胞中既限制了其细胞毒性潜能，也限制了其耗竭潜能，并影响外周肿瘤免疫的维持。 | Mao, Z. | PDF | N/A | PD-1 prelimits both the cytotoxic and exhaustion potential in thymic CD8+ T cells and impacts the maintenance of peripheral tumor immunity | | 非侵入性环境DNA技术揭示了东比利牛斯山脉西部松鸡（Tetrao urogallus aquitanicus）的生态和遗传状况 | Buso, P. | PDF | N/A | Non-invasive eDNA reveals the ecological and genetic status of the Western Capercaillie (Tetrao urogallus aquitanicus) in the Eastern Pyrenees | | 测试极端塑料菌丝假说：放牧是否会诱导腐生真菌的发育可塑性？ | Aguilar-Trigueros, C. A. | PDF | N/A | Testing the extreme plastic mycelium hypothesis: Does grazing induce developmental plasticity in saprotrophic fungi? | | 以下是这段英文的中文翻译：

《浮萍科浮萍属Alatae组的基因组多样性与系统发育，包括推测的物种Lemna aequinoctialis、Le. perpusilla和Le. aoukikusa》

这段文字主要描述了两个方面：一是随着年龄增长，视网膜色素上皮细胞中的自噬途径会出现衰退；二是局部应用海藻糖对小鼠因光诱导导致的视网膜外层变性具有保护作用。 | Cox, K. | PDF | N/A | Age-Associated Decline in Autophagy Pathways in Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light-induced Outer Retinal Degeneration in Mice | | 解码MASLD进展：基于分子轨迹的疾病动态建模框架 | Kamzolas, I. | PDF | N/A | Decoding MASLD Progression: A Molecular Trajectory-Based Framework for Modelling Disease Dynamics | | Ohno-miRNAs：源自全基因组复制的基因内miRNA对 | Agasso, L. | PDF | N/A | Ohno-miRNAs: intragenic miRNA pairs derived from whole-genome duplication | | 靶向组蛋白乙酰化能够实现对炎症途径的表观遗传调控，这是类风湿性关节炎的一种新型治疗策略。 | Brinkmann, M. | PDF | N/A | Targeting histone acetylation enables epigenetic modulation of inflammatory pathways, a novel therapeutic strategy for rheumatoid arthritis | | 巴塔哥尼亚峡湾/水道与开阔海域的对比：智利南部海岸的浮游植物分子多样性 | Fuenzalida, G. | PDF | N/A | Patagonian fjords/channels vs. open ocean: phytoplankton molecular diversity in Southern Chilean coast | | 脂质保护性二硫键是ApoE4与人类散发性阿尔茨海默病之间缺失的分子联系。 | Ramsden, C. E. | PDF | N/A | Lipid-protecting disulfide bridges are the missing molecular link between ApoE4 and sporadic Alzheimers disease in humans | | 运动后的β波反弹反映了运动适应过程中的策略性重新瞄准，但并不反映重新瞄准的准确性。 | Will, M. | PDF | N/A | Post-movement beta rebound reflects strategic re-aiming during motor adaptation, but not re-aiming accuracy | | 使用切线空间脑网络进行功能连接组指纹识别的有效性 | Curic, D. | PDF | N/A | Efficacy of functional connectome fingerprinting using tangent-space brain networks | | 脑膜瘤和胶质瘤对全脑动态的影响 | Junca, A. | PDF | N/A | Impact of meningioma and glioma on whole-brain dynamics | | 小胶质细胞SIRT2缺乏加剧阿尔茨海默病认知下降和淀粉样蛋白病理 | Sola-Sevilla, N. | PDF | N/A | Microglial SIRT2 deficiency aggravates cognitive decline and amyloid pathology in Alzheimer's disease | | 芬戈莫德（FTY720）在阿尔茨海默病APP/PS1模型中对海马突触可塑性和记忆表现的挽救作用，伴随着鞘脂、多胺和磷脂饱和度组成的代谢校正。 | Kalecky, K. | PDF | N/A | Rescue of hippocampal synaptic plasticity and memory performance by Fingolimod (FTY720) in APP/PS1 model of Alzheimer's disease is accompanied by correction in metabolism of sphingolipids, polyamines, and phospholipid saturation composition | | 斑马鱼肠道内分泌细胞亚型分化及激素产生 | Morash, M. | PDF | N/A | Intestinal enteroendocrine cell subtype differentiation and hormone production in zebrafish | | 以单细胞分辨率揭示发育中人类面部的基因表达模式，展示了细胞类型对正常面部变异和疾病风险的贡献。 | Khouri-Farah, N. | PDF | N/A | Gene expression patterns of the developing human face at single cell resolution reveal cell type contributions to normal facial variation and disease risk | | 间隔区扩展在高保真Cas9基因组编辑中协调特异性和活性 | Lu, Z. | PDF | N/A | Spacer Extension Reconciles Specificity and Activity in High-Fidelity Cas9 Genome Editing | | 印度本土牛基因组组装揭示了重排热点和免疫相关遗传多样性 | Azam, S. | PDF | N/A | Genome assemblies of Indian desi cattle reveals hotspots of rearrangements and immune-related genetic diversity | | Lecanemab能够与源自转基因小鼠模型的淀粉样蛋白-β纤维结构结合，这些结构类似于阿尔茨海默病中的I型、II型和北极型折叠。 | Peralta Reyes, F. S. | PDF | N/A | Lecanemab binds to transgenic mouse model-derived amyloid-β fibril structures resembling Alzheimer 's disease type-I, type-II and Arctic folds | | 基于半定量评分和人工智能驱动的定量图像分析，渐进性囊性纤维化胰腺外分泌和内分泌病理的形态功能时间线如下：

早期阶段：
外分泌功能：胰腺外分泌功能开始出现轻微下降，腺泡细胞逐渐减少，导管系统出现轻微扩张。
内分泌功能：胰岛细胞数量保持相对稳定，胰岛素分泌功能正常。
中期阶段：
外分泌功能：腺泡细胞进一步减少，导管系统显著扩张，纤维化开始出现，外分泌功能明显下降。
内分泌功能：胰岛细胞数量开始减少，胰岛素分泌功能出现轻微下降。
晚期阶段：
外分泌功能：腺泡细胞几乎完全消失，导管系统严重扩张，纤维化广泛存在，外分泌功能严重受损。
内分泌功能：胰岛细胞数量显著减少，胰岛素分泌功能严重下降，可能出现糖尿病症状。

摘要：本研究通过生物信息学方法对STAT1基因的非编码UTR（非翻译区）变异进行了深入分析，揭示了这些变异如何影响miRNA的结合、mRNA的稳定性以及潜在的致癌作用。研究发现，特定的UTR变异可能破坏miRNA与mRNA的正常结合，导致mRNA稳定性下降，进而可能促进肿瘤的发生和发展。这些发现为理解STAT1基因在癌症中的作用提供了新的视角，并为未来的癌症治疗策略提供了潜在的理论依据。 | Kamal, E. | PDF | N/A | Bioinformatics Analysis of Non-Coding UTR Variants in STAT1 Reveals Disruption of miRNA Binding, mRNA Stability, and Oncogenic Potential | | KILDA：从kmer中识别KIV-2重复序列 | Molitor, C. | PDF | N/A | KILDA: identifying KIV-2 repeats from kmers | | 阴离子脂质催化生成具有细胞毒性的胰岛素寡聚体。 | Saha, J. | PDF | N/A | Anionic lipid catalyzes the generation of cytotoxic insulin oligomers | | 原子力显微镜揭示了小鼠和人类卵母细胞中与皮质结构相关的机械特性差异。 | Bulteau, R. | PDF | N/A | Atomic Force Microscopy reveals differences in mechanical properties linked to cortical structure in mouse and human oocytes | | 异速生长扩散和焦点粘附集体组织是由细胞尺度的几何约束协调的。 | Bimbard, C. | PDF | N/A | Allometric spreading and focal adhesion collective organization are coordinated by cell-scale geometrical constraints | | 温度跃迁法：一种筛选选择性、慢结合和紧密结合抑制剂的方法，针对处于非天然状态的激酶。 | Suzuki, S. | PDF | N/A | Temperature vaulting: A method for screening selective, slow- and tight-binding inhibitors targeting kinases in their non-native state | | 为大鼠（Rattus norvegicus）使用Void Whizzard的空斑测定可视化优化 | Ruetten, H. | PDF | N/A | Void spot assay visualization optimization for use of Void Whizzard in rats (Rattus norvegicus) | | 核质Lamin A/C通过调节局部H3K9me3和ADP-核糖基化水平来控制应激条件下的复制叉重启。 | Cherdyntseva, V. | PDF | N/A | Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels | | 假单胞菌（Pseudomonas putida）KT2440中的ISPpu9插入序列能够生成各种环状中间体，从而实现模块化转座。 | Pares-Guillen, E. | PDF | N/A | The ISPpu9 insertion sequence of Pseudomonas putida KT2440 generates various circular intermediates enabling modular transposition | | REV7与ATRIP结合并抑制ATR激酶活性。 | Biller, M. | PDF | N/A | REV7 associates with ATRIP and inhibits ATR kinase activity | | 负频率依赖性选择有助于丁香假单胞菌效应器库的模块化结构 | Li, S. | PDF | N/A | Negative frequency-dependent selection contributes to modular structure of effector repertoires in Pseudomonas syringae | | 检测植物共生体在两个自然环境梯度中的分化情况 | Chang, C.-Y. | PDF | N/A | Testing for divergence in a plant symbiont across two natural environmental gradients |

BioRxiv 2025-01-17 Papers

标题	作者	PDF链接	代码仓库	Title
《从Macoma balthica（一种以线粒体双单亲遗传为特征的贝类）的雄性和雌性类型mtDNA推断出的不一致种群结构》	Le Cam, S.	PDF	N/A	Discordant population structure inferred from male- and female-type mtDNAs from Macoma balthica, a bivalve species characterized by doubly uniparental inheritance of mitochondria
5-羟色胺在非快速眼动睡眠期间调节齿状回中的极慢振荡	Turi, G. F.	PDF	N/A	Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep
在自闭症谱系障碍的Pten杂合模型中，初级体感神经元的发育发生了改变	Fernandez, A.	PDF	N/A	Altered primary somatosensory neuron development in a Pten heterozygous model for autism spectrum disorder
行为上无关的特征匹配增强了神经和行为工作记忆的读取能力	Karabay, A.	PDF	N/A	Behaviorally irrelevant feature matching increases neural and behavioral working memory readout
在清醒行为中的猕猴中观察到的伽马爆发皮层活动	Acland, B. T.	PDF	N/A	Gamma-burst cortical activity in awake behaving macaques
对转录因子组合结合的系统性分析揭示了TEAD1在人类器官发生过程中作为组织特异性转录因子的拮抗剂。	Garcia-Mora, A.	PDF	N/A	Systematic analysis of transcription factor combinatorial binding uncovers TEAD1 as an antagonist of tissue-specific transcription factors in human organogenesis
使用PTM-POSE系统分析剪接对蛋白质异构体翻译后修饰多样性的影响	Crowl, S.	PDF	N/A	Systematic analysis of the effects of splicing on the diversity of post-translational modifications in protein isoforms using PTM-POSE
抑制HDAC7可重编程组蛋白H3.3的景观，从而在癌细胞中诱导异染色质扩散和DNA复制缺陷。	Hassan, O.	PDF	N/A	Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells.
兴奋性守护者：甘丙肽在全脑兴奋性中的多重作用	Rieser, N. N.	PDF	N/A	Guardian of Excitability: Multifaceted Role of Galanin in Whole Brain Excitability
REV-ERBβ结合口袋动态及其对小分子调节剂合理设计的启示	Srivastava, S.	PDF	N/A	REV-ERBβ Binding Pocket Dynamics with Implications for Rational Design of Small Molecule Modulators
在自然刺激下，大脑活动的偏离与人格特质有关。	Jajcay, L.	PDF	N/A	Deviation from typical brain activity during naturalistic stimulation is related to personality traits
在生物物理学上现实的兴奋-抑制性脉冲网络中进行高效编码	Koren, V.	PDF	N/A	Efficient coding in biophysically realistic excitatory-inhibitory spiking networks
对Mic60 Mitofilin结构域的祖先序列重建揭示了支持酵母呼吸作用的残基	Benning, F. M. C.	PDF	N/A	Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast
微生物热性能曲线的快速适应性进化	Liu, M. H.	PDF	N/A	Rapid adaptive evolution of microbial thermal performance curves
Caspase-11在Polg相关线粒体疾病模型中驱动巨噬细胞过度炎症反应。	VanPortfliet, J. J.	PDF	N/A	Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease
外膜成纤维细胞在肺血管疾病中指导平滑肌细胞状态转变	Crnkovic, S.	PDF	N/A	Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
低频胫神经调控增加排尿活动——一项人体初步研究及计算模型	McConnell-Trevillion, A.	PDF	N/A	Low-Frequency Tibial Neuromodulation Increases Voiding Activity - a Human Pilot Study and Computational Model
PowerCHORD：构建用于生物节律发现的最佳实验设计	Silverthorne, T. L.	PDF	N/A	PowerCHORD: constructing optimal experimental designs for biological rhythm discovery
MARK2通过磷酸化CAMSAP2在定向细胞迁移中调节高尔基体的重新定向。	Xu, P.	PDF	N/A	MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migration
腹侧被盖区中间神经元再探：GABA和谷氨酸投射神经元形成局部突触	Oriol, L.	PDF	N/A	Ventral tegmental area interneurons revisited: GABA and glutamate projection neurons make local synapses
空间分辨组学数据的跨模态表示与多样本整合	Li, Z.	PDF	N/A	Cross-modality representation and multi-sample integration of spatially resolved omics data
对脓肿分枝杆菌的遗传分析揭示了与全球质粒分布相关的基因组多样性	Ohse, K.	PDF	N/A	Genetic analysis of Mycobacterium abscessus reveals genomic diversity linked to global plasmid distribution
外显子包含特征能够准确估计剪接因子的活性。	Anglada-Girotto, M.	PDF	N/A	Exon inclusion signatures enable accurate estimation of splicing factor activity
微囊藻中标记基因及细胞内无定形碳酸钙生物矿化候选基因表达的昼夜变化	Bruley, A.	PDF	N/A	Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis
通过结合偶氮苯的双色光照射实现酶的即时可逆调控	Lahmy, R.	PDF	N/A	Instantly Reversible Enzyme Regulation via Dichromatic Irradiation of Incorporated Azobenzene
《囊性纤维化变异体的蛋白质稳态景观揭示了药物反应的脆弱性》	McDonald, E. F.	PDF	N/A	Proteostasis Landscapes of Cystic Fibrosis Variants Reveals Drug Response Vulnerability
单价伪天然产物降解剂通过KLHDC3增强IDO1的天然降解	Hennes, E.	PDF	N/A	Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3
简单、普遍的规则预测营养级相互作用强度	Coblentz, K. E.	PDF	N/A	Simple, universal rules predict trophic interaction strengths
核内Argonaute蛋白NRDE-3在胚胎发育过程中切换小RNA伙伴，以介导时间特异性的基因调控活动。	Chen, S.	PDF	N/A	Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity
节律性活动网络中突触电导的推理技术及其在呼吸中枢模式生成电路中的应用	Molkov, Y. I.	PDF	N/A	Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits
在昆虫的隐蔽分类群中：细菌丰度、多样性和分布的模式	Nowak, K. H.	PDF	N/A	Beneath the scuttle: Patterns of bacterial abundance, diversity and distribution in an insect dark taxon
VVBlue检测法：一种基于染料排除法的板式可读细胞活力检测方法，用于化学品的毒理学测试	Vitipon, M.	PDF	N/A	The VVBlue assay: a plate-readable, dye exclusion-based cell viability assay for the toxicological testing of chemicals
电影诱发的大脑活动与连接性的遗传性	Gruskin, D. C.	PDF	N/A	Heritability of movie-evoked brain activity and connectivity
酶促蛋白质融合，100%产物得率	Fuchs, A. C. D.	PDF	N/A	Enzymatic Protein Fusions with 100% Product Yield
系统给予催产素和β-3受体激动剂（CL 316243）对饮食诱导肥胖雄性大鼠体重和脂肪含量的影响	Slattery, J. D.	PDF	N/A	Effects of systemic oxytocin and beta-3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet-induced obese rats
克氏锥虫细胞图谱：用于理解寄生虫种群异质性和分化的单细胞资源。	Laidlaw, R.	PDF	N/A	The Trypanosoma cruzi cell atlas; a single-cell resource for understanding parasite population heterogeneity and differentiation.
植物基与动物肉质的质地剖面分析及流变学研究	Dunne, R. A.	PDF	N/A	Texture profile analysis and rheology of plant-based and animal meat
稳定感染重组卡波西肉瘤相关疱疹病毒的内皮细胞表现出独特的粘弹性和形态学特性。	Shabangu, M. M.	PDF	N/A	Endothelial cells stably infected with recombinant Kaposi's sarcoma-associated herpesvirus display distinct viscoelastic and morphological properties
单细胞图谱揭示t(8;21)急性髓系白血病中与年龄相关的基因调控网络	Whittle, J.	PDF	N/A	Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML
使用开源软件对全片脂肪组织图像进行高通量测量以确定脂肪细胞大小	Ramalho, A. C.	PDF	N/A	High-throughput measurement of adipocyte size with open-source software using whole-slide adipose tissue images
铜绿假单胞菌产生的绿脓菌素和1-羟基吩嗪对人鼻上皮细胞内钙离子浓度、线粒体功能及细胞存活率的影响	Thompson, J. C.	PDF	N/A	Effects of Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine on intracellular calcium, mitochondrial function, and viability in human nasal epithelial cells
使用MMseqs2进行GPU加速的同源性搜索	Kallenborn, F.	PDF	N/A	GPU-accelerated homology search with MMseqs2
实施克鲁维梭菌（Clostridium luticellarii）基因组尺度模型以升级合成气发酵过程	Scott, W. T.	PDF	N/A	Implementation of a Clostridium luticellarii genome-scale model for upgrading syngas fermentations
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帕金森病中冻结步态的丘脑下特征	Collomb-Clerc, A.	PDF	N/A	Subthalamic Signature of Freezing of Gait in Parkinson Disease
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从宏观到微观：埃及伊蚊的全新基因组使得近缘和远缘物种间的比较基因组学研究成为可能	Morinaga, G.	PDF	N/A	From macro to micro: De novo genomes of Aedes mosquitoes enable comparative genomics among close and distant relatives
人类与啮齿动物的癫痫发作显示出与扩散性去极化之间的动态相互作用	Norby, J. H.	PDF	N/A	Human and Rodent Seizures Demonstrate a Dynamic Interplay with Spreading Depolarizations
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电堆肥：一项新兴技术	Abendroth, C.	PDF	N/A	Electro-composting: an emerging technology
以下是这段英文的中文翻译：

分析木棉（Bombax ceiba）芽分化过程中生理物质与内源激素的相互作用

如果需要进一步调整或补充，请告诉我！ | WANG, S. | PDF | N/A | Analysis of the interactions between physiological substances and endogenous hormones in Bombax ceiba bud differentiation | | 受损的类淋巴清除功能独立地导致帕金森病的不良预后。 | Zarkali, A. | PDF | N/A | Impaired glymphatic clearance independently contributes to poor outcomes in Parkinsons disease | | 检测帕金森病患者泪液中的α-突触核蛋白种子活性 | Canaslan, S. | PDF | N/A | Detection of alpha synuclein seeding activity in tear fluid in patients with Parkinson's disease | | 帕金森病中脑电图对运动强度的反应 | Alizadeh, Z. | PDF | N/A | EEG Responses to Exercise Intensity in Parkinson's Disease | | 青光眼患者的刺激驱动脑脊液动力学受损 | Bang, J. W. | PDF | N/A | Stimulus-driven cerebrospinal fluid dynamics is impaired in glaucoma patients | | 集成单细胞亲和力测试的B细胞分析能够识别出预测抗体亲和力的基因特征。 | Chirichella, M. | PDF | N/A | Integrated single-cell analyses of affinity-tested B-cells enable the identification of a gene signature to predict antibody affinity. | | 2008-2020年挪威多重耐药MRSA的趋势与特征 | Ronning, T. G. | PDF | N/A | Trends and characteristics of multidrug resistant MRSA in Norway 2008-2020 | | 双黄酮类化合物可能通过抑制β淀粉样蛋白的内化来减轻其细胞毒性事件。 | Haque, M. A. | PDF | N/A | Biflavonoids can potentially inhibit amyloid beta internalization to mitigate its cytotoxic events | | 加强保护法律执法：将损害、修复及多元自然价值标准纳入基于个体的生物多样性违法行为严重性评估 | Ghijselinck, D. | PDF | N/A | Strengthening conservation law enforcement: incorporating harm, remediation and plural nature value criteria into an individual-based assessment of biodiversity offence gravity | | 建筑环境专业人士欢迎规定性生态学证据，以加强与利益相关者的沟通，促进生物多样性包容性城市的发展：来自全球北方和南方专业人士的见解 | Lu, J. | PDF | N/A | Built-environment professionals welcome prescriptive ecology evidence to enhance communication with stakeholders for biodiversity-inclusive cities: Insights from professionals in both the Global North and South | | X染色体和剂量补偿机制在复杂性状遗传学中的作用 | Fu, Y. | PDF | N/A | Role of X chromosome and dosage compensation mechanisms in complex trait genetics | | GenVarLoader：一个加速的数据加载器，用于将深度学习应用于个性化基因组学 | Laub, D. | PDF | N/A | GenVarLoader: An accelerated dataloader for applying deep learning to personalized genomics | | 当视觉场景发生变化时，蚂蚁在导航过程中会更多地摆动和扫描。 | deeti, s. | PDF | N/A | Ants oscillate and scan more in navigation when the visual scene changes | | 新型碳水化合物取代的吲唑衍生物靶向SGLT1增强受体酪氨酸激酶抑制剂在癌症治疗中的疗效 | Qi, H. | PDF | N/A | Novel Carbohydrate-substituted Indazole Derivatives Targeting SGLT1 Enhance the Efficacy of Receptor Tyrosine Kinase Inhibitors in Cancer Therapy | | 柠檬酸的胞质运输保护营养匮乏的胰腺癌免受铁死亡的影响。 | Kneebone, A. | PDF | N/A | Cytosolic transport of citrate protects nutrient-austere pancreatic cancer from ferroptosis | | 肌肉力量与体积在单侧渐进阻力训练中的关系 | Deiwert, D. D. | PDF | N/A | Muscle Strength and Size Relationships with Unilateral Progressive Resistance Training | | 杏仁核-皮层回路用于编码广义恐惧记忆。 | Vincent, C. J. | PDF | N/A | An amygdala-cortical circuit for encoding generalized fear memories. | | 纵向T细胞受体库分析揭示了溃疡性结肠炎中动态克隆T细胞群体的变化。 | Briggs, K. C. | PDF | N/A | Longitudinal T cell repertoire analysis reveals dynamic clonal T cell populations in Ulcerative Colitis | | 植物驯化不会减少根际微生物组的多样性 | Hernandez-Teran, A. | PDF | N/A | Plant domestication does not reduce diversity in root microbiomes | | 日本树蛙蝌蚪（Dryophytes japonicus）对多种蜻蜓若虫的捕食者诱导尾部颜色变化 | Noda, A. | PDF | N/A | Predator-Induced Tail Coloration Toward Diverse Dragonfly Nymphs in Tadpoles of the Japanese Tree Frog (Dryophytes japonicus) | | 日本树蛙蝌蚪（Dryophytes japonicus）对多种蜻蜓若虫的捕食者诱导尾部着色 | Noda, A. | PDF | N/A | Predator-Induced Tail Coloration Toward Diverse Dragonfly Nymphs in Tadpoles of the Japanese Tree Frog (Dryophytes japonicus) | | 性选择特征预测了一种性别角色反转的滨鸟中雌性偏向的留居行为。 | Luna, L. W. | PDF | N/A | Sexually selected traits predict female-biased philopatry in a sex-role reversed shorebird | | ERGA-BGE基因组：Pinctada radiata（Leach, 1814）：首批莱塞普斯移民之一 | Vasileiadou, K. | PDF | N/A | ERGA-BGE genome of Pinctada radiata (Leach, 1814): one of the first Lessepsian migrants | | 光合共生的阴暗面：光合共生双壳类动物中与转座元件和未知开放阅读框相关的复杂重复序列导致其线粒体基因组异常庞大

在这段翻译中，我尽量保持了原文的科学性和准确性，同时使中文表达流畅易懂。以下是翻译的要点解释：

"The Dark Side of Photosymbiosis" 翻译为 "光合共生的阴暗面"，旨在传达光合共生现象中可能存在的负面或复杂的一面。
"Elaborate Repeats with TEs and Unknown ORFs" 翻译为 "与转座元件和未知开放阅读框相关的复杂重复序列"，其中：
"Elaborate Repeats" 译为 "复杂重复序列"，强调这些重复序列的复杂性和多样性。
"TEs" 是 "Transposable Elements" 的缩写，译为 "转座元件"，这是遗传学中常见的术语。
"ORFs" 是 "Open Reading Frames" 的缩写，译为 "开放阅读框"，指的是潜在的蛋白质编码区域。
"in Photosymbiotic Bivalves" 翻译为 "在光合共生双壳类动物中"，明确了研究对象。
"Made Exceptionally Big Metazoan Mitogenomes" 翻译为 "导致其线粒体基因组异常庞大"，其中：
"Exceptionally Big" 译为 "异常庞大"，强调其大小超出常规。
"Metazoan Mitogenomes" 译为 "线粒体基因组"，指的是动物细胞中线粒体的遗传物质。

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C. | PDF | N/A | SH2D2A is an indicator of favourable prognosis in bladder cancer and is enriched in Treg cells | | 辐射治疗对脑微血管蛋白质组学的长期影响：暴露后六个月的分析 | Subramanian, V. | PDF | N/A | Long-Term Effects of Radiation Therapy on Cerebral Microvessel Proteome: A Six-Month Post-Exposure Analysis | | spEMO：探索基础模型在分析空间多组学数据中的能力 | Liu, T. | PDF | N/A | spEMO: Exploring the Capacity of Foundation Models for Analyzing Spatial Multi-Omic Data | | 由于个体间存在差异，需要对人类大脑的时间干扰刺激进行个体化优化。 | Brahma, T. | PDF | N/A | On the need of individually optimizing temporal interference stimulation of human brains due to inter-individual variability | | 光触发质子选择性载流子通过光开关膜 | Pfeffermann, J. | PDF | N/A | Phototriggered proton-selective carrier currents through photoswitchable membranes | | 将氢交换与分子动力学相结合，以提高配体结合预测的准确性 | Walters, B. T. | PDF | N/A | Integrating Hydrogen Exchange with Molecular Dynamics for Improved Ligand Binding Predictions | | 浸润性小叶癌的综合多组学分析揭示了在对他莫昔芬耐药性中，精氨琥珀酸合成酶的沉默以及核苷酸生物合成的上调。 | Gupta, A. | PDF | N/A | Invasive lobular carcinoma integrated multi-omics analysis reveals silencing of Arginosuccinate synthase and upregulation of nucleotide biosynthesis in tamoxifen resistance | | 通过高通量筛选与计算生物物理学定义多囊蛋白药效团。 | Guadarrama, E. | PDF | N/A | Defining the Polycystin Pharmacophore Through HTS & Computational Biophysics. | | 新型GLP-1R/GIPR双重激动剂HISHS-2001的结合动力学、偏向性、受体内化及其在体外和体内对胰岛素分泌的影响 | Manchanda, Y. | PDF | N/A | Binding Kinetics, Bias, Receptor Internalization and Effects on Insulin Secretion in vitro and in vivo of a Novel GLP-1R/GIPR Dual Agonist, HISHS-2001 | | 合成与验证一种能够淬灭DNA荧光的金属有机框架材料 | Goodrich, J. | PDF | N/A | Synthesis and validation of a metal-organic framework able to quench DNA fluorescence | | 将轻度认知障碍与正常认知进行分类：fMRI复杂性匹配Tau PET表现 | Jann, K. | PDF | N/A | Classifying Mild Cognitive Impairment from Normal Cognition: fMRI Complexity Matches Tau PET Performance | | 由DNA易位细菌限制-修饰酶进行的核小体重塑 | Sharma, S. S. G. | PDF | N/A | Remodeling of nucleosome by a DNA translocating bacterial restriction-modification enzyme | | 面对竞争时，不完善的知识可能导致对共享资源的持续过度利用。 | Aarts, G. | PDF | N/A | In the face of competition, imperfect knowledge can lead to sustainable exploitation of a shared resource. | | 甲氨蝶呤治疗下类风湿性关节炎的时间分辨免疫动态 | Preglej, T. | PDF | N/A | Time-resolved immune dynamics in rheumatoid arthritis under Methotrexate therapy | | 对BRAF抑制剂的抗性导致黑色素瘤对Chk1抑制的敏感性 | Carvalho, D. 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BioRxiv 2025-01-16 Papers

标题	作者	PDF链接	代码仓库	Title
在由蛋白质聚集体引起的应激条件下，蛋白酶体通过扩散和依赖细胞骨架的机制进行重新分布。	Morten, M. J.	PDF	N/A	Redistribution of proteasomes through diffusion and cytoskeleton-dependent mechanisms upon stress induced by protein aggregates
SRSF3是心外膜形成的关键调控因子。	Lupu, I.-E.	PDF	N/A	SRSF3 is a key regulator of epicardial formation
无尺度模型下的染色体结构、动力学与力学研究	Grosse-Holz, S.	PDF	N/A	Scale-free models of chromosome structure, dynamics, and mechanics
在非快速眼动睡眠期间进行的目标记忆重新激活是否需要互补的快速眼动睡眠以促进记忆巩固？	Sifuentes Ortega, R.	PDF	N/A	Does targeted memory reactivation during NREM sleep require complementary REM sleep for memory consolidation?
以下是这段英文的中文翻译：

证据表明，通过合成的自体四倍体秀丽隐杆线虫（Caenorhabditis elegans）可以增强抗逆性，这与多倍体化有关。

基于仿生透明质酸支架的导电MXene基微网格3D打印技术，用于引导和增强神经修复应用中的电刺激。

解释： - 3D-Printing：3D打印 - Electroconductive：导电的 - MXene-based：基于MXene的（MXene是一种二维材料） - Micro-meshes：微网格 - Biomimetic：仿生的 - Hyaluronic Acid-based Scaffold：基于透明质酸的支架 - Directs and Enhances：引导和增强 - Electrical Stimulation：电刺激 - Neural Repair Applications：神经修复应用

山兔（Lepus timidus）染色体水平参考基因组组装

翻译说明： - "Chromosome-level" 译为“染色体水平”，表示基因组的组装精度达到了染色体级别。 - "reference genome assembly" 译为“参考基因组组装”，指的是作为标准参考的基因组序列。 - "mountain hare" 译为“山兔”，是 Lepus timidus 的常见中文名称。

扁盘动物分泌细胞类型与摄食、先天免疫和行为调节有关

翻译说明： - Placozoan 指的是“扁盘动物”，一种简单的多细胞生物。 - secretory cell types 指的是“分泌细胞类型”。 - implicated in 表示“与……有关”或“涉及”。 - feeding 是“摄食”。 - innate immunity 是“先天免疫”。 - regulation of behavior 是“行为调节”。

“果胶酸裂解酶样基因在陆地植物中的进化，及其在寄生植物吸器形成中的作用。”

结构基础揭示了驯化的II类内含子样逆转录酶在宿主细胞DNA修复中的功能进化

结构机制：泛素连接酶适配蛋白Cyclin F识别E2F1

翻译说明： - "Structural mechanism" 翻译为 "结构机制"。 - "recognition" 翻译为 "识别"。 - "E2F1" 是蛋白质名称，保留不变。 - "ubiquitin ligase adaptor" 翻译为 "泛素连接酶适配蛋白"。 - "Cyclin F" 是蛋白质名称，保留不变。

高分辨率烟草花叶病毒盘状结构通过冷冻电镜获得

DSB诱导后染色体丢失频率的定量分析

翻译说明： - "Quantitative analysis" 翻译为 "定量分析" - "frequency" 翻译为 "频率" - "chromosome loss" 翻译为 "染色体丢失" - "DSB induction" 翻译为 "DSB诱导"（DSB指DNA双链断裂）

内容翻译：本研究探讨了USDA 110型慢生根瘤菌（Bradyrhizobium diazoefficiens）在从浮游生长状态向生物膜形成状态转变过程中，Tad菌毛所扮演的角色。Tad菌毛是一种细胞表面附属结构，已知在多种细菌的黏附、聚集及生物膜形成中起关键作用。通过一系列遗传和表型分析，我们发现Tad菌毛对于USDA 110型菌株在固体表面上的初期附着和生物膜结构的建立至关重要。缺乏Tad菌毛的突变体表现出显著的生物膜形成缺陷，这强调了这些结构在细菌群落生活方式中的重要性。此外，我们的研究还揭示了Tad菌毛在调节细胞间相互作用和环境适应性中的潜在机制，为理解慢生根瘤菌的生态适应性和生物膜相关功能提供了新的见解。 | Iglesias, J. A. | PDF | N/A | Role of Tad Pili during the transition from Planktonic to Biofilm State in Bradyrhizobium diazoefficiens USDA 110 | | 探索古代粪便中的病原体谱 | Capone, D. | PDF | N/A | Exploring the Pathogen Profiles of Ancient Feces | | 单细胞RNA测序揭示了克氏锥虫群体中类转唾液酸酶超家族基因的表达异质性 | Inchausti, L. | PDF | N/A | Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations | | 妇科癌症中免疫检查点抑制剂反应的代谢特征：基于通量平衡分析的见解 | Idumah, G. | PDF | N/A | Metabolic Signatures of Immune Checkpoint Inhibitor Response in Gynecologic Cancers: Insights from Flux Balance Analysis | | 以下是这段英文的中文翻译：

临床和分类学特征：一种新型尿路病原体——兰州普罗维登斯菌

翻译说明： - "Clinical and Taxonomic Characterization" 翻译为 "临床和分类学特征"。 - "Novel" 翻译为 "新型"。 - "Urinary Tract Pathogen" 翻译为 "尿路病原体"。 - "Providencia lanzhouensis" 是细菌的学名，直接保留原文，翻译为 "兰州普罗维登斯菌"。

物种依赖性代谢的共价nsP2蛋白酶抑制剂及其体内抗甲病毒活性

翻译解释： - Species Dependent Metabolism：物种依赖性代谢，指的是不同物种对同一化合物的代谢方式可能不同。 - Covalent nsP2 Protease Inhibitor：共价nsP2蛋白酶抑制剂，nsP2是一种病毒蛋白酶，这种抑制剂通过共价键与之结合。 - in Vivo Anti-alphaviral Activity：体内抗甲病毒活性，指的是该化合物在活体实验中对甲病毒（Alphavirus）具有抑制或杀灭作用。

Sarm1基因缺失成年小鼠体内单根激光切断角膜神经纤维的形态动力学研究

翻译说明： - "In vivo" 翻译为 "体内" - "Morphological Dynamics" 翻译为 "形态动力学" - "Single Laser-Axotomized" 翻译为 "单根激光切断" - "Corneal Nerve Fibers" 翻译为 "角膜神经纤维" - "Sarm1-Null" 翻译为 "Sarm1基因缺失" - "Adult Mice" 翻译为 "成年小鼠"

致幻剂暴露后前额叶皮层神经元类型中替代剪接的持续性大规模变化

翻译解释： - Persistent：持续性的 - large-scale changes：大规模变化 - alternative splicing：替代剪接（一种基因表达调控机制） - prefrontal cortical neuron types：前额叶皮层神经元类型 - psychedelic exposure：致幻剂暴露

在这段翻译中，"Plectin"是一种蛋白质的名称，通常不翻译，保留原文。"Regulates"翻译为“调节”，表示控制或管理。"Focal Adhesion Dynamics"翻译为“粘着斑动力学”，指的是细胞与细胞外基质之间的动态相互作用。"Cytoskeletal Organization"翻译为“细胞骨架组织”，涉及细胞内部结构的排列和组织。"Mouse Astrocytes"翻译为“小鼠星形胶质细胞”，指的是小鼠大脑中的一种支持性细胞。"Implications for Reactive Astrogliosis"翻译为“对反应性星形胶质细胞增生的影响”，指的是研究结果对理解星形胶质细胞在损伤或疾病中的反应性变化的意义。 | Furlani, B. | PDF | N/A | Plectin Regulates Focal Adhesion Dynamics and Cytoskeletal Organization in Mouse Astrocytes: Implications for Reactive Astrogliosis | | VeCell：一个Fiji插件，用于揭示大胶质细胞发育及其与血管接近性的时空动态 | Guille, N. | PDF | N/A | VeCell: A Fiji Plugin to unveil the spatio-temporal dynamics of macroglial cell development and proximity to blood vessels | | 视觉搜索中的不确定性：来自自然刺激下计算模型与行为实验的洞见 | Bujia, G. | PDF | N/A | Uncertainty during visual search: Insights from a computational model and behavioral experiment in natural stimuli | | 年龄在战略控制回忆内容中的影响，通过场景重建的调节反映出来。 | de Chastelaine, M. | PDF | N/A | Effects of age in the strategic control of recollected content as reflected by modulation of scene reinstatement | | 内侧内嗅皮层-海马去同步化与阿尔茨海默病病理小鼠模型中记忆障碍的出现相平行 | Vetere, L. M. | PDF | N/A | Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology | | 在概率线索下，反向阿尔法振荡塑造感知偏差 | Tarasi, L. | PDF | N/A | Backward alpha oscillations shape perceptual bias under probabilistic cues | | 验证结构张量分析在脑组织显微镜中用于方向估计的有效性 | Gray, B. | PDF | N/A | Validation of Structure Tensor Analysis for Orientation Estimation in Brain Tissue Microscopy | | 钙调磷酸酶介导的GAP-43调控对于神经突触和突触的形成至关重要，并且能够防止α-突触核蛋白诱导的神经退行性变。 | Zaichick, S. | PDF | N/A | Calcineurin-mediated regulation of GAP-43 is essential for neurite and synapse formation and protects against α-synuclein-induced degeneration | | 个性化α频段经颅交流电刺激对疼痛感知和神经振荡的调节作用：一项针对健康参与者的假刺激对照研究 | Fathi, Y. | PDF | N/A | Individualized Alpha-tACS for Modulating Pain Perception and Neural Oscillations: A Sham-Controlled Study in Healthy Participants | | 丘脑参与定义了非快速眼动（NREM）睡眠中不同的慢波亚型。 | Bergamo, D. | PDF | N/A | Thalamic involvement defines distinct slow-wave subtypes in NREM sleep | | P4B-2412作为磷酸二酯酶4B放射性配体用于正电子发射断层扫描成像的临床前评估 | Song, Z. | PDF | N/A | Preclinical Evaluation of P4B-2412 as Phosphodiesterase 4B Radioligand for Positron Emission Tomography Imaging | | 优化SARS-CoV-2 RBD边界以增强大肠杆菌表达 | Biswas, A. | PDF | N/A | Optimizing SARS-CoV-2 RBD Boundaries for Enhanced E. coli Expression | | 技术和生物来源的噪声干扰了多重增强子AAV筛选。 | Hunker, A. C. | PDF | N/A | Technical and biological sources of noise confound multiplexed enhancer AAV screening | | 脂磷壁酸在金黄色葡萄球菌细胞壁完整性中的作用 | Bae, T. | PDF | N/A | The role of lipoteichoic acid in Staphylococcus aureus cell wall integrity | | 对人类肠道细菌中胆汁盐水解酶活性的研究揭示了共轭次级胆汁酸的产生 | Lucas, L. N. | PDF | N/A | Investigation of Bile Salt Hydrolase Activity in Human Gut Bacteria Reveals Production of Conjugated Secondary Bile Acids | | 一种适应于缺氧冷泉沉积物的无板纲软体动物中用于化学共生的多层膜细胞器 | Li, Y. | PDF | N/A | A multilamellar organelle for chemosymbiosis in an aplacophoran mollusc adapted to anoxic cold seep sediment | | 根际定殖细菌在原生生物微生物组中持续存在 | Taerum, S. J. | PDF | N/A | Rhizosphere-colonizing bacteria persist in the protist microbiome | | 环境因素驱动胃肠道黏液的细菌降解 | Arias, S. L. | PDF | N/A | Environmental factors drive bacterial degradation of gastrointestinal mucus | | 末端补体复合物（无论是否含有C9）增强了针对淋病奈瑟菌的抗菌活性。 | Lamb, E. R. | PDF | N/A | Terminal complement complexes with or without C9 potentiate antimicrobial activity against Neisseria gonorrhoeae | | 通过对保守RNA结构进行计算机筛选，鉴定出巴西利什曼原虫中一种新型长链非编码RNA的功能特性研究

这段翻译将原标题“Functional Characterization of a Novel Long Non-Coding RNA in Leishmania braziliensis Identified Through Computational Screening for Conserved RNA Structures”转化为中文，同时保持了原文的科学性和准确性。翻译中，“Functional Characterization”译为“功能特性研究”，“Novel Long Non-Coding RNA”译为“新型长链非编码RNA”，“Leishmania braziliensis”保留为“巴西利什曼原虫”，“Identified Through Computational Screening for Conserved RNA Structures”则译为“通过对保守RNA结构进行计算机筛选鉴定出”。整体翻译流畅，符合中文表达习惯，同时准确传达了原文的科学信息。 | Espada, C. R. | PDF | N/A | Functional Characterization of a Novel Long Non-Coding RNA in Leishmania braziliensis Identified Through Computational Screening for Conserved RNA Structures | | 创建和验证用于蛋白质检测和分析的全蛋白质组酵母文库 | Baruch, D. | PDF | N/A | Creation and Validation of a Proteome-Wide Yeast Library for Protein Detection and Analysis | | 城市作物展现出与自然生态系统相当的有机碳储存潜力。 | Prieto, B. J. | PDF | N/A | Urban crops demonstrate comparable potential for organic carbon storage as natural ecosystems. | | RPA磷酸化编码的启动和调节机制通过Cdk1/Wee1信号回路实现 | Roshan, P. | PDF | N/A | Mechanism of RPA phosphocode priming and tuning by Cdk1/Wee1 signaling circuit | | 错配修复因子Mlh1-Pms1利用ATP来压缩和重塑DNA。 | Collingwood, B. W. | PDF | N/A | The mismatch repair factor Mlh1-Pms1 uses ATP to compact and remodel DNA | | 一种针对疟疾病原体恶性疟原虫溴结构域PfBDP1的新型抑制剂 | Amann, M. | PDF | N/A | A novel inhibitor against the bromodomain PfBDP1 of the malaria pathogen Plasmodium falciparum | | 致癌的CCDC6-RET融合产物是一种依赖ATP和ADP的双重激酶，通过顺式磷酸化发挥作用。 | Martin-Hurtado, A. | PDF | N/A | The oncogenic CCDC6-RET fusion product is a dual ATP and ADP-dependent kinase that functions via cis-phosphorylation | | 在刚果民主共和国与安哥拉边境地区，发现了登革热病毒传播的证据以及多样化的伊蚊病毒组。 | He, W. | PDF | N/A | Evidence of dengue virus transmission and a diverse Aedes mosquito virome on the Democratic Republic of Congo-Angola border | | 使用多层链图分析猪源弯曲杆菌中氟喹诺酮类和大环内酯类耐药性的风险因素 | Wang, C. A. | PDF | N/A | Risk factors for fluoroquinolone- and macrolide-resistance among swine Campylobacter coli using multi-layered chain graphs | | 噬菌体防御系统的丰度在不同环境中有所变化，并随着病毒密度的增加而增加。 | Meaden, S. | PDF | N/A | Phage defence system abundances vary across environments and increase with viral density | | 在抗生素时代之后，历史临床分离株中的基因组耐药性在频率和移动性上都有所增加。 | Kaul, A. | PDF | N/A | Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics | | 这段文字的中文翻译是：

“黑曲霉转录因子MsnA与VelB之间的分子回路协调真菌应激与发育反应”

解释： - Molecular circuit：分子回路，指的是生物体内分子之间的相互作用和调控网络。 - Aspergillus nidulans：黑曲霉，一种常见的模式真菌，常用于科学研究。 - Transcription factors：转录因子，调控基因表达的蛋白质。 - MsnA and VelB：两种特定的转录因子名称。 - Coordinate：协调，指调控或整合不同的生物过程。 - Fungal stress and developmental responses：真菌的应激反应和发育反应，分别指真菌在应对环境压力（如氧化、温度变化等）和生长发育过程中的调控机制。

BioRxiv 2025-01-15 Papers

标题	作者	PDF链接	代码仓库	Title
调查催产素和信任是否在营销行为的安慰剂效应中起作用	Schelski, D. S.	PDF	N/A	Investigation of whether oxytocin and trust play a role in placebo effects of marketing actions
人类运动单位放电模式揭示了不同收缩水平下运动神经元在神经调节和抑制驱动方面的差异。	Skarabot, J.	PDF	N/A	Human motor unit discharge patterns reveal differences in neuromodulatory and inhibitory drive to motoneurons across contraction levels
连续且完整的囊胚菌肠道微生物组相关原生生物组装揭示了其向宿主生态进化的多样性。	Lind, A.	PDF	N/A	Contiguous and complete assemblies of Blastocystis gut microbiome-associated protists reveal evolutionary diversification to host ecology
Neuromark PET：一种多变量方法，用于从fMRI和PET数据中估计全脑fMRI引导的内在网络和连接组。	Saha, D. K.	PDF	N/A	Neuromark PET: A multivariate method for estimating whole brain fMRI guided intrinsic networks and connectomes from fMRI and PET data
使用阿塔卡马清晰技术实现超高分辨率的3D成像	Lacko, L.	PDF	N/A	3D Imaging with Superior Resolution Using Atacama Clear
TimberTracer: 一个用于评估森林管理及采伐木材产品替代对碳固存影响的综合框架。	Boukhris, I.	PDF	N/A	TimberTracer: A Comprehensive Framework for the Evaluation of Carbon Sequestration by Forest Management and Substitution of Harvested Wood Products.
Piscis：一种新颖的F1分数损失估计器，通过深度学习实现荧光显微镜图像中的精确斑点检测	Niu, Z.	PDF	N/A	Piscis: a novel loss estimator of the F1 score enables accurate spot detection in fluorescence microscopy images via deep learning
雷帕霉素及其类似物大环内酯类免疫抑制剂对TRPM8离子通道的直接调节作用	Toth, B. I.	PDF	N/A	Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants
受体酪氨酸激酶CAD96CA和FGFR1作为昆虫保幼激素的细胞膜受体发挥作用。	Li, Y.-X.	PDF	N/A	Receptor tyrosine kinases CAD96CA and FGFR1 function as the cell membrane receptors of insect juvenile hormone
SAMson：一种利用SAM自动提取啮齿动物大脑的工具	Soler, D. P.	PDF	N/A	SAMson: an automated brain extraction tool for rodents using SAM
使用空间重新编程遗传电路	Alejaldre, L.	PDF	N/A	Reprogramming genetic circuits using space
使用单细胞转录组学对细胞周期状态和类似静止的G0状态进行分类	O'Connor, S. A.	PDF	N/A	Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomics
SeqLengthPlot：一个易于使用的基于Python的工具，用于从fasta文件中可视化和检索序列长度，并具有可调节的分割点。	Dominguez-Perez, D.	PDF	N/A	SeqLengthPlot: An easy-to-use Python-based Tool for Visualizing and Retrieving Sequence Lengths from fasta files with a Tunable Splitting Point
生物螺（Biomphalaria snails）的器官特异性微生物组	Carruthers, L. V.	PDF	N/A	Organ-Specific Microbiomes of Biomphalaria Snails
匹配栖息地选择与物种分布范围的演化	Shirani, F.	PDF	N/A	Matching Habitat Choice and the Evolution of a Species' Range
鸟类白蛋白糖化率的变化表明其对相对高血糖的抵抗性，而非符合“生活节奏综合症”假说。	Moreno Borrallo, A.	PDF	N/A	Variation in albumin glycation rates in birds suggests resistance to relative hyperglycaemia rather than conformity to the pace of life syndrome hypothesis
在自由活动的小鼠中进行精确的皮肤刺激	Parkes, I.	PDF	N/A	Precision cutaneous stimulation in freely moving mice
Opto-CLIP揭示了CA1神经元激活时FMRP对mRNA的动态调控	Singer, R. A.	PDF	N/A	Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation
从单核RNA测序数据进行等位基因失衡分析的实验与计算方法	Simmons, S. K.	PDF	N/A	Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data
大规模神经网络刺激的灵活建模：针对细胞外电位虚拟电极记录工具（VERTEX）的电学和光学扩展	Pierce, A. F.	PDF	N/A	Flexible modeling of large-scale neural network stimulation: electrical and optical extensions to The Virtual Electrode Recording Tool for EXtracellular Potentials (VERTEX)
短期记忆错误与后顶叶皮层神经活动的漂移密切相关。	Choi, J. H.	PDF	N/A	Short-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex
外周阿片受体拮抗作用可缓解芬太尼引起的心肺抑制，且不会引发厌恶行为。	Ruyle, B.	PDF	N/A	Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive behavior
在生物系统中使用代谢探针进行光学光热红外成像	Shuster, S. O.	PDF	N/A	Optical photothermal infrared imaging using metabolic probes in biological systems
神经网络结构如何改变大脑的自组织临界性	Sugimoto, Y. A.	PDF	N/A	How neural network structure alters the brain's self-organized criticality
脊髓前体细胞中CDKN1c/p57kip2的低表达驱动了细胞分裂从增殖模式向神经生成模式的转变。	Mida, B.	PDF	N/A	A low CDKN1c/p57kip2 expression in spinal progenitors drives the transition from proliferative to neurogenic modes of division
使用webKnossos在电子显微镜体积中进行高效的细胞范围内线粒体映射	Jiang, Y.	PDF	N/A	Efficient cell-wide mapping of mitochondria in electron microscopic volumes using webKnossos
量化双光子成像中血流动力学闭塞效应	Yogesh, B.	PDF	N/A	Quantification of the effect of hemodynamic occlusion in two-photon imaging
小脑性伸手共济失调对运动学和动力学需求的敏感性	Oh, K.	PDF	N/A	Sensitivity of Cerebellar Reaching Ataxia to Kinematic and Dynamic Demands
UniversalEPI：一种基于广义注意力的深度集成模型，用于准确预测多种细胞类型和条件下的增强子-启动子相互作用	Grover, A.	PDF	N/A	UniversalEPI: a generalized attention-based deep ensemble model to accurately predict enhancer-promoter interactions across diverse cell types and conditions
一个特定谱系的驱动线库将发育中的神经元回路与果蝇腹侧神经索的行为联系起来。	Soffers, J. H.	PDF	N/A	A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord.
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人类ORC2对表观遗传学和染色体结构的调控	Su, Z.	PDF	N/A	Regulation of epigenetics and chromosome structure by human ORC2
工程化的生物神经网络作为基本逻辑运算符	Küchler, J.	PDF	N/A	Engineered biological neural networks as basic logic operators
YAP通过与RIF1相互作用来缓解鳞状细胞癌中的复制应激。	Bojko, J.	PDF	N/A	YAP engages RIF1 to dampen replication stress in squamous cell carcinoma.
在静止啮齿类动物中，包括摄食行为在内的身体动作期间，海马尖波涟漪减少。	Sakairi, T.	PDF	N/A	Hippocampal sharp-wave ripples decrease during physical actions including consummatory behavior in immobile rodents
在枕颞叶皮层中对生物力学上（不）可能的人类运动的神经编码	Marrazzo, G.	PDF	N/A	Neural encoding of biomechanically (im)possible human movements in occipitotemporal cortex
追踪北海大西洋鳕鱼40年间的稳定性变化	Tao, H.-H.	PDF	N/A	Tracking changes in stability of North Sea Atlantic cod in 40 years
α-突触核蛋白聚集体通过隔离和附带降解抑制ESCRT-III	Sitron, C. S.	PDF	N/A	Alpha-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation
一种新型小鼠尾部模型用于不同剂量局部照射后辐射性皮肤损伤的研究	Wang, G.	PDF	N/A	A novel murine tail model for radiation-induced skin injury following localized irradiation at varying doses
MDL-001：一种口服、安全且耐受性良好的广谱病毒聚合酶抑制剂	Woods, V.	PDF	N/A	MDL-001: An Oral, Safe, and Well-Tolerated Broad-Spectrum Inhibitor of Viral Polymerases
在大肠杆菌中重组生产来自人类病原体金黄色葡萄球菌的功能活性α-溶血素	Diaz-Varela, J. L.	PDF	N/A	Recombinant production in Escherichia coli of functionally active alpha-hemolysin from the human pathogen Staphylococcus aureus
APE1活性位点残基Asn174稳定了AP位点，并且对催化作用至关重要。	DeHart, K. M.	PDF	N/A	APE1 active site residue Asn174 stabilizes the AP-site and is essential for catalysis
社区、归属感与同伴互动：参与者的体验反映了包容性STEM教学学习社区中促进实践的一致性	Codding, D.	PDF	N/A	Community, Belonging, and Peer-Engagement: Participant Experiences Reflect Consistency of Facilitation Practices in Inclusive STEM Teaching Learning Communities
组合表型景观使细菌能够抵抗噬菌体感染	Gupta, A.	PDF	N/A	Combinatorial phenotypic landscape enables bacterial resistance to phage infection
GCN5a是一种端粒赖氨酸乙酰转移酶，其缺失会促使弓形虫进入潜伏状态。	Dey, V.	PDF	N/A	GCN5a is a telomeric lysine acetyltransferase whose loss primes Toxoplasma gondii for latency
GCN5a是一种端粒赖氨酸乙酰转移酶，其缺失会导致弓形虫（Toxoplasma gondii）进入潜伏状态。	Dey, V.	PDF	N/A	GCN5a is a telomeric lysine acetyltransferase whose loss primes Toxoplasma gondii for latency
无菌新生小鼠的微生物群组装	Kennedy, E.	PDF	N/A	Microbiota assembly of specific pathogen-free neonatal mice
拟南芥真菌内生菌培养滤液的乙酸乙酯提取物的杀线虫和杀虫活性	Diaz-Gonzalez, S.	PDF	N/A	Nematicidal and insecticidal activity of ethyl acetate extracts from culture filtrates of Arabidopsis thaliana fungal endophytes
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探索黑琴鸡（Lyrurus tetrix）的视觉系统：结合实验与分子方法，为减少碰撞策略提供信息	Potier, S.	PDF	N/A	Exploring the visual system of the black Grouse (Lyrurus tetrix): Combining experimental and molecular approaches to inform strategies for reducing collisions
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遗传背景决定了癌症演化的轨迹。	Aitken, S. J.	PDF	N/A	Genetic background sets the trajectory of cancer evolution
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池包装AAV文库中广泛长度和同源性依赖的嵌合现象	Lalanne, J.-B.	PDF	N/A	Extensive length and homology dependent chimerism in pool-packaged AAV libraries
通过共价连接克服基于mEOS的AAA+解折叠酶报告基因中的荧光损失	Walter, I.	PDF	N/A	Overcoming Fluorescence Loss in mEOS-based AAA+ Unfoldase Reporters Through Covalent Linkage
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在大肠杆菌乳清酸磷酸核糖转移酶的二聚体界面中，存在一种高度稳定的工程化二硫键。	Kurauskas, V.	PDF	N/A	A highly stable engineered disulfide bond in the dimer interface of E. coli orotate phosphoribosyl transferase
使用PARTI监测细胞内单体特异性酰基-tRNA水平	Pressimone, M. A.	PDF	N/A	Monitoring monomer-specific acyl-tRNA levels in cells with PARTI
通过深度强化学习绘制具有抗菌效力的肽	Dong, R.	PDF	N/A	Painting Peptides with Antimicrobial Potency through Deep Reinforcement Learning
通过内切酶SMG6抑制NMD，实现双链RNA反应、新抗原呈递以及肝细胞癌的抑制。	Arpa, E. S.	PDF	N/A	Double-stranded RNA responses, neoantigen presentation and suppression of hepatocellular carcinoma through NMD inhibition via endonuclease SMG6
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加勒比地区的红树林在末次盛冰期时位于何处？	Rull, V.	PDF	N/A	Where were the Caribbean mangroves during the Last Glacial Maximum?
以下是这段文字的中文翻译：

"厌声症症状的严重程度归因于灵活性受损和过度反刍思维"

翻译说明： - Misophonia 翻译为 "厌声症"，这是一种对特定声音产生强烈负面情绪反应的病症。 - Symptoms Severity 翻译为 "症状的严重程度"。 - Attributed to 翻译为 "归因于"。 - Impaired Flexibility 翻译为 "灵活性受损"，这里可能指认知或情绪调节的灵活性。 - Heightened Rumination 翻译为 "过度反刍思维"，指反复思考负面情绪或事件的倾向。

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B. | PDF | N/A | Different artificial light modalities during daytime have all positive effects on attention and alertness | | 多巴胺对纹状体-苍白球突触传递的调节模式 | Lee, Y. | PDF | N/A | Distinct modes of dopamine modulation on striatopallidal synaptic transmission | | 探索分段线性动力系统模型在认知神经动力学中的适用性 | Wu, J. | PDF | N/A | Exploring the Suitability of Piecewise-Linear Dynamical System Models for Cognitive Neural Dynamics | | 特定纤维束的神经突密度（而非髓鞘化）将多基因评分与一般智力联系起来。 | Stammen, C. | PDF | N/A | Neurite density but not myelination of specific fiber tracts links polygenic scores to general intelligence | | 时间特异性和蛋白质特异性的S-棕榈酰化支持突触和神经网络的可塑性 | Pytys, A. | PDF | N/A | Temporal and protein-specific S-palmitoylation supports synaptic and neural network plasticity | | 因果性尖峰时序依赖可塑性防止循环网络中的组装融合 | Yang, X. | PDF | N/A | Causal Spike Timing Dependent Plasticity Prevents Assembly Fusion in Recurrent Networks | | 在fMRI分析中追求共线性解决方案时产生的无意偏差 | Mumford, J. A. | PDF | N/A | Unintended bias in the pursuit of collinearity solutions in fMRI analysis | | 无DNA CRISPR基因组编辑在树莓（Rubus idaeus）中的应用：通过RNP介导的原生质体转染及Indel分析技术的比较 | Creeth, R. | PDF | N/A | DNA-free CRISPR Genome Editing in Raspberry (Rubus idaeus) through RNP-mediated Protoplast Transfection and Comparison of Indel Analysis Techniques | | 克服木质屏障：菟丝子实现高效将感染性克隆转移至木本植物 | Sierra-Mejia, A. | PDF | N/A | Overcoming the Woody Barrier: Dodder Enables Efficient Transfer of Infectious Clones to Woody Plants | | 拟南芥脱水素ERD14通过伴侣作用将BRL3受体引导至适当位置，从而赋予植物抗旱能力。 | Cano-Delgado, A. I. | PDF | N/A | The Arabidopsis dehydrin ERD14 chaperones the BRL3 receptor to confer drought resistance | | 系统发育与分类学视角下的桦木属研究：基于低覆盖度全基因组测序和质体组分析，重点关注乌克兰特有珍稀物种克洛科维奇桦（Betula klokovii Zaverucha）

本研究通过低覆盖度全基因组测序和质体组分析，深入探讨了桦木属（Betula）的系统发育关系和分类学特征，特别聚焦于乌克兰特有的珍稀物种——克洛科维奇桦（Betula klokovii Zaverucha）。研究旨在揭示该物种的遗传背景及其在桦木属中的系统发育位置，为桦木属的分类和进化研究提供新的见解。 | Tarieiev, A. | PDF | N/A | Phylogenetic and taxonomic insights into Betula: low-coverage whole genome sequencing and plastome analysis with focus on the rare Ukrainian endemic species Betula klokovii Zaverucha | | 水稻乙烯受体OsERS1负调控水稻幼苗的茎生长和耐盐性。 | Morita, S. | PDF | N/A | The rice ethylene receptor OsERS1 negatively regulates the shoot growth and salt tolerance in rice seedlings | | FaRIF在草莓果实成熟中的核心作用：解析其靶标及相互作用网络 | Martin-Pizarro, C. | PDF | N/A | FaRIF at the Core of Strawberry Fruit Ripening: Deciphering its Targets and Interaction Networks | | C4模型植物绿狗尾草中非光化学淬灭途径的修饰揭示了与C3植物相比共有和独特的光保护机制

在这项研究中，科学家们对C4模型植物绿狗尾草（Setaria viridis）的非光化学淬灭（NPQ）途径进行了修饰，以探索其光保护机制。非光化学淬灭是植物在强光条件下保护光合作用系统免受损伤的一种重要机制。通过与C3植物进行比较，研究发现C4植物不仅拥有与C3植物共有的光保护机制，还具备一些独特的光保护策略。这些发现有助于深入理解C4植物在强光环境下的适应性和光合作用效率，为未来作物改良提供了新的思路。 | Milburn, G. | PDF | N/A | Modification of Non-photochemical Quenching Pathways in the C4 Model Plant Setaria viridis Revealed Shared and Unique Photoprotection Mechanisms as Compared to C3 Plants | | 促进生长，假丝酵母提取物助力植物茁壮成长 | Levy, M. | PDF | N/A | Make it grow, Pseudozyma aphidis extract promotes plant growth | | Wnt/β-catenin信号通路促进环节动物Capitella teleta非再生组织的后轴再生 | Kunselman, L. | PDF | N/A | Wnt/β-catenin signaling promotes posterior axial regeneration in non-regenerative tissue of the annelid Capitella teleta | | 可吸收性海藻酸盐栓塞微球用于肌肉骨骼栓塞应用 | Agarwal, S. | PDF | N/A | Resorbable alginate embolic microsphere for Musculoskeletal embolization applications | | 稳定、易操作、完全自体的电纺聚合物-肽皮肤替代物用于严重烧伤 | Cohen-Gerassi, D. | PDF | N/A | Stable, Easy-to-Handle, Fully Autologous Electrospun Polymer-Peptide Skin Equivalent for Severe Burn Injuries | | 在人类淋巴结的有序微生理模型中，初始T细胞与B细胞的相互作用及滤泡外抗体反应的启动 | Zatorski, J. M. | PDF | N/A | Initiation of primary T cell--B cell interactions and extrafollicular antibody responses in an organized microphysiological model of the human lymph node | | 工程化抗菌支架保护骨髓间充质干细胞植入物免受细菌感染 | Khalid Ahmed, A. M. | PDF | N/A | Engineered antimicrobial scaffolds protect bone marrow mesenchymal stem cell-Based Implants from bacterial infections | | 猕猴皮层对犹他光电极阵列急性植入的皮层反应 | Villamarin-Ortiz, A. | PDF | N/A | Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex | | 二维，还是非二维？探究组织切片的垂直信号完整性 | Tiesmeyer, S. | PDF | N/A | 2D, or not 2D? Investigating Vertical Signal Integrity of Tissue Slices | | 利用单细胞RNA测序技术对PDAC中T细胞耗竭和癌症生物标志物的新见解 | Saleem, M. U. | PDF | N/A | Novel Insights into T-Cell Exhaustion and Cancer Biomarkers in PDAC Using Single Cell RNA Sequencing | | CellSP：用于亚细胞空间转录组数据的模块发现和可视化 | Aggarwal, B. | PDF | N/A | CellSP: Module discovery and visualization for subcellular spatial transcriptomics data | | SFCalculator：连接深度生成模型与晶体学 | Li, M. | PDF | N/A | SFCalculator: connecting deep generative models and crystallography | | EWS-FLI1在人类胚胎间充质干细胞中的表达导致转录重编程、DNA损伤修复缺陷和尤文肉瘤的形成 | Hernandez-Munoz, I. | PDF | N/A | EWS-FLI1 Expression in Human Embryonic MSCs Leads to Transcriptional Reprograming, Defective DNA Damage Repair and Ewing Sarcoma | | 强制安装E-选择素配体增强了过继转移T细胞的归巢和疗效 | Hou, Y. | PDF | N/A | Enforced E-selectin ligand installation enhances homing and efficacy of adoptively transferred T cells | | 地塞米松诱导发育中骨骼毒性的机制：单细胞视角

桥木提取物对氯化镉诱导的Wistar大鼠生殖激素失衡、氧化应激、肝肾损伤、血液学紊乱及急性毒性的改善作用

翻译说明： - Ameliorative Effects：改善作用 - Brideliaferruginea Extracts：桥木提取物（Brideliaferruginea 是一种植物，中文名可能为“铁锈桥木”） - Cadmium Chloride-Induced：氯化镉诱导的 - Reproductive Hormone Imbalance：生殖激素失衡 - Oxidative Stress：氧化应激 - Hepatorenal Damage：肝肾损伤 - Hematological Disorders：血液学紊乱 - Acute Toxicity：急性毒性 - Wistar Rats：Wistar大鼠（一种常用的实验大鼠品系）

希望这段翻译对你有帮助！如果需要进一步调整或解释，请随时告诉我。 | Adewuyi, H. A. | PDF | N/A | Ameliorative Effects of Brideliaferruginea Extracts on Cadmium Chloride-Induced Reproductive Hormone Imbalance, Oxidative Stress, Hepatorenal Damage, Hematological Disorders, and Acute Toxicity in Wistar Rats | | 糖介导的ATG101调控拟南芥中碳缺乏诱导的自噬 | Boycheva Woltering, S. | PDF | N/A | Sugar-mediated control of ATG101 modulates carbon deficiency-induced autophagy in Arabidopsis | | 芒格黑树莓：探究其作为悬钩子属植物病毒指示剂的作用 | Sierra-Mejia, A. | PDF | N/A | Munger black raspberry: Insights into its role as a virus indicator for Rubus species | | 螺旋路径的扩展斯托克斯定理：在络石茎和花中旋转流的应用 | Tozzi, A. | PDF | N/A | An extended Stokes' theorem for spiral paths: applications to rotational flows in Trachelospermum jasminoides stems and flowers | | 揭示病毒-人类蛋白质相互作用中的致癌性网络特征 | Zambelli, F. | PDF | N/A | Unraveling the network signatures of oncogenicity in virus-human protein-protein interactions | | 表征肾脏损伤和修复中的基因调控网络集合体 | Tannenbaum, E. | PDF | N/A | Characterizing Gene Regulatory Network Ensembles in Kidney Injury and Repair | | 微生物代谢中的渗透与生活方式转变 | Supo-Escalante, R. | PDF | N/A | Percolation and lifestyle transition in microbial metabolism | | OT-I TCR对外源和自身抗原的3D亲和力预测了它们的2D亲和力，并揭示了抗原识别的不完美性。 | Huhn, A. | PDF | N/A | The 3D affinities of the OT-I TCR to foreign and self-antigens predict their 2D affinities and reveal imperfect antigen discrimination | | 人类T滤泡辅助细胞（T follicular helper cells, Tfh）在体外的分化需要STAT3和SMAD信号通路的细胞因子之间的协同作用，而这一过程受到IL-2的抑制。 | Foster, W. S. | PDF | N/A | Differentiation of human T follicular helper cells in vitro requires co-operation between STAT3 and SMAD signaling cytokines that is restrained by IL-2 | | 预测代谢功能障碍相关脂肪性肝病风险使用患者来源的诱导多能干细胞 | Qin, Y. | PDF | N/A | Predicting Metabolic Dysfunction Associated Steatotic Liver Disease Risk Using Patient-Derived Induced Pluripotent Stem Cells | | 婴儿呼吸道合胞病毒（RSV）感染通过CXCL11-CXCR7信号通路使气道平滑肌中的β2-肾上腺素能受体脱敏。 | Zhao, C. | PDF | N/A | Infant RSV infection desensitizes β2-adrenergic receptor via CXCL11-CXCR7 signaling in airway smooth muscle | | 将肌肉纤维嵌入水凝胶中可以提高其在长时间离体培养中的存活率并保持收缩功能。 | Vonk, L. A. | PDF | N/A | Embedding muscle fibers in hydrogel improves viability and preserves contractile function during prolonged ex vivo culture | | 1990年至2022年全球陆地生态系统人类改造的范围与变化 | Theobald, D. M. | PDF | N/A | Global extent and change in human modification of terrestrial ecosystems from 1990 to 2022 | | 增加静水压力对海洋微生物酶活性的影响 | Balmonte, J. P. | PDF | N/A | Effects of increasing hydrostatic pressures on marine microbial enzymatic activities | | 智利南部底层植被的低组成稳定性增强了在移除大型褐藻（牛海带）情况下的功能稳定性 | Fica Rojas, E. | PDF | N/A | Understory low compositional stability enhances functional stability in response to bull kelp removal in southern Chile | | 隐秘蝾螈的分子检测：泥蝾螈（Pseudotriton montanus）检测的环境DNA（eDNA）分析方法的开发。 | Brammell, B. F. | PDF | N/A | Molecular detection of a cryptic salamander: Development of an eDNA assay for the detection of the mud salamander (Pseudotriton montanus). | | 跨哺乳动物物种的蛋白质分子钟整合模型 | Saini, A. | PDF | N/A | Integrated model of the protein molecular clock across mammalian species | | 基于ARDUINO的器官灌注系统 | Di Domenico, S. | PDF | N/A | ARDUINO-BASED ORGAN PERFUSION SYSTEM | | 通过整合AlphaFold3和模板信息准确预测蛋白质复合物的化学计量比 | Liu, J. | PDF | N/A | Accurate Stoichiometry Prediction of Protein Complexes by Integrating AlphaFold3 and Template Information | | 通过整合AlphaFold3和模板信息精确预测蛋白质复合物的化学计量比 | Liu, J. | PDF | N/A | Accurate Stoichiometry Prediction of Protein Complexes by Integrating AlphaFold3 and Template Information | | 使用转录组和突变数据进行消化道肿瘤的聚类分析 | Tally, D. G. | PDF | N/A | Clustering Digestive Tract Tumors Using Transcriptomic and Mutation Data | | 使用tFold-TCR快速准确地建模TCR-肽-MHC复合物 | Wu, F. | PDF | N/A | Fast and accurate modeling of TCR-peptide-MHC complexes using tFold-TCR | | CSMA：一款用于分析伤口愈合实验的ImageJ插件 | Pham, T. T. | PDF | N/A | CSMA: an ImageJ Plugin for the Analysis of Wound Healing Assays | | 生长中的细菌链的扭结和屈曲不稳定性 | McMahon, S. G. | PDF | N/A | Kinking and buckling instability in growing bacterial chains | | 紫杉醇通过重新极化肿瘤相关巨噬细胞，诱导侵袭性乳腺癌细胞的重新形成。 | Friedman-DeLuca, M. | PDF | N/A | Paclitaxel causes de novo induction of invasive breast cancer cells by repolarizing tumor-associated macrophages | | 天冬酰胺内肽酶通过调控ATR通路促进乳腺癌的放射抗性 | Morillo-Huesca, M. | PDF | N/A | Asparagine endopeptidase promotes radioresistance in breast cancer through ATR pathway modulation | | 对比学习用于组学引导的全片视觉嵌入表示 | Yu, S. | PDF | N/A | Contrastive Learning for Omics-guided Whole-slide Visual Embedding Representation | | 一种用于蛋白质自组装的可调亲和融合标签 | Kimbrough, H. | PDF | N/A | A tunable affinity fusion tag for protein self-assembly | | 《细菌丝氨酸-苏氨酸激酶图谱》扩展了激酶组的功能多样性。 | O'Boyle, B. M. | PDF | N/A | Atlas of the Bacterial Serine-Threonine Kinases expands the functional diversity of the kinome | | EPSD 2.0：一个跨真核生物物种的蛋白质磷酸化位点更新数据库 | Chen, M. | PDF | N/A | EPSD 2.0: An Updated Database of Protein Phosphorylation Sites across Eukaryotic Species | | 利用高维免疫表型分析技术对快速冷冻保存的液体活检样本中的免疫细胞组成进行图谱绘制。 | Pedersen, J. G. | PDF | N/A | Using high-dimensional immunophenotyping for mapping immune cell composition in rapid cryopreserved liquid biopsies | | TCR信号通过NFATc1限制了IL-15诱导的人记忆CD8+ T细胞的NK样激活。 | Lee, H. | PDF | N/A | TCR signaling via NFATc1 constrains IL-15-induced NK-like activation of human memory CD8+ T cells | | 基因组范围内染色质环的绝对定量 | Jusuf, J. M. | PDF | N/A | Genome-wide absolute quantification of chromatin looping | | Crb3与NF2：一对通过Rho/ROCK信号通路控制顶端连接组装及屏障功能的动态搭档 | Fan, S. | PDF | N/A | Crb3 and NF2: A dynamic duo that controls assembly of the apical junctions and barrier function via Rho/ROCK signaling | | 在肾单位痨（Nephronophthisis）的背景下对前列腺素受体激动剂和优帕替林的评估 | Tata, A. | PDF | N/A | Evaluation of Prostaglandin Receptor Agonists and Eupatilin in the Context of Nephronophthisis | | 光学代谢成像揭示了POLG突变型巨噬细胞中的代谢转变和线粒体异质性。 | Hu, L. | PDF | N/A | Optical metabolic imaging identifies metabolic shifts and mitochondria heterogeneity in POLG mutator macrophages | | PI31是20S免疫蛋白酶体组装的正向调节因子。 | Wang, J. | PDF | N/A | PI31 is a positive regulator of 20S immunoproteasome assembly | | IFT20通过VE-钙粘蛋白的内吞运输调节淋巴管内皮细胞的细胞间连接。 | Paulson, D. | PDF | N/A | IFT20 regulates lymphatic endothelial cell-cell junctions via endocytic trafficking of VE-cadherin | | 一种在进化上保守的微小RNA，miR-185，调控了可能导致植入失败的关键通路。 | Smith, W. | PDF | N/A | An evolutionarily conserved microRNA, miR-185, regulates key pathways that may contribute to implantation failure. | | 核斑点的动态变化受多磷酸盐对CLK蛋白的抑制调控 | Lazaro, B. | PDF | N/A | Nuclear Speckle Dynamics are Controlled by Polyphosphate Inhibition of CLK Proteins | | 中央时钟驱动肌肉干细胞中的代谢节律 | Sica, V. | PDF | N/A | The central clock drives metabolic rhythms in muscle stem cells | | 纤毛发生过程中固有的膜拓扑问题通过纤毛招募磷脂翻转酶得以解决。 | Wang, Z. | PDF | N/A | The membrane topology problem inherent in ciliogenesis is solved by ciliary recruitment of a phospholipid flippase | | 邻近相互作用组学鉴定出RAI14、EPHA2和PHACTR4为脊椎动物Wnt/平面细胞极性通路的关键组成部分 | Gomoryova, K. | PDF | N/A | Proximity interactomics identifies RAI14, EPHA2 and PHACTR4 as essential components of Wnt/planar cell polarity pathway in vertebrates | | 建模视网膜色素变性59型：Dhdds T206A和Dhdds K42E敲入突变小鼠在表型上相似。 | Nguyen, M. N. | PDF | N/A | Modeling Retinitis Pigmentosa 59: Dhdds T206A and Dhdds K42E knock-in mutant mice are phenotypically similar. | | NAMPT活性在驱动自身免疫过程中起着关键作用，这些过程是小鼠1型糖尿病发展的特征。 | Egbase, D. | PDF | N/A | NAMPT activity plays a key role in driving autoimmune processes that characterize type 1 diabetes development in mice | | Fanconi贫血中的miR-29a-3p与TGF-β轴：推动代谢功能障碍与基因组稳定性的机制 | Bertola, N. | PDF | N/A | miR-29a-3p and TGF-beta Axis in Fanconi Anemia: Mechanisms Driving Metabolic Dysfunction and Genome Stability | | 砷化合物直接与核运输因子结合，破坏了核质运输。 | Lorentzon, E. | PDF | N/A | Direct binding of arsenicals to nuclear transport factors disrupts nucleocytoplasmic transport | | 角蛋白中间丝机械性地定位黑色素颗粒以实现基因组的光保护作用。 | Benito-Martinez, S. | PDF | N/A | Keratin intermediate filaments mechanically position melanin pigments for genome photoprotection | | Kremen1 依赖性受体诱导 SEC24C 和 ATG9A 依赖的自噬性细胞死亡 | Brahim, S. | PDF | N/A | Kremen1 dependence receptor induces SEC24C- and ATG9A-dependent autophagic cell death | | 代谢综合征在小鼠模型中加剧了SARS-CoV-2疾病的严重程度，并降低了mRNA疫苗的效力。 | Geeling, E. | PDF | N/A | Metabolic syndrome enhances SARS-CoV-2 disease severity and reduces mRNA vaccine efficacy in a mouse model | | 核糖体蛋白系统地理学为微生物群落基因组解析调查的有效性提供了定量见解。 | Schechter, M. S. | PDF | N/A | Ribosomal protein phylogeography offers quantitative insights into the efficacy of genome-resolved surveys of microbial communities | | Trypstatin作为一种新型TMPRSS2抑制剂，具有广谱抗冠状病毒和流感病毒的功效 | Lawrenz, J. | PDF | N/A | Trypstatin as a Novel TMPRSS2 Inhibitor with Broad-Spectrum 1 Efficacy Against Corona and Influenza Viruses | | 揭开NSP3的神秘面纱：AlphaFold2辅助下的SARS-CoV-2蛋白结构域解析 | Edich, M. | PDF | N/A | Unlocking the Secrets of NSP3: AlphaFold2-assisted Domain Determination in SARS-CoV-2 Protein | | Hsa-MiR-483-3p通过TGFβ2/SMAD4信号通路调控糖皮质激素反应性人小梁网细胞中的细胞外基质蛋白 | Haribalaganesh, R. | PDF | N/A | Hsa-MiR-483 -3p Regulates the Extracellular Matrix Proteins via TGFbeta2/SMAD4 Signaling in the Glucocorticoid-responsive Human Trabecular Meshwork Cells | | 蛋白磷酸酶4是果蝇神经干细胞中中心体不对称性所必需的 | Segura, R. C. | PDF | N/A | Protein phosphatase 4 is required for centrosome asymmetry in fly neural stem cells | | 肠道微生物淀粉样蛋白与内源性淀粉样蛋白的相互作用可能驱动阿尔茨海默病中的小胶质细胞过度活跃和神经炎症 | Javed, I. | PDF | N/A | Interaction of Gut-Microbial Amyloids with Endogenous Amyloids can Drives Microglial Hyperactivity and Neuroinflammation in Alzheimers Disease | | 利用糖皮质激素受体拮抗作用增强心脏再生生长因子和细胞因子的疗效 | Da Pra, S. | PDF | N/A | Harnessing glucocorticoid receptor antagonization to enhance the efficacy of cardiac regenerative growth factors and cytokines | | 依赖蛋白质O-甘露糖基化的内质网相关降解 | Lemus, L. | PDF | N/A | ER-associated degradation relying on protein O-mannosylation | | 解读COVID-19中的宿主-病原体界面：对高影响力转录本的表观转录组修饰的精确分子洞察 | Mazdziarz, M. A. | PDF | N/A | Deciphering the Host-Pathogen Interface in COVID-19: The precision molecular insight into epitranscriptomic modifications of high-impact transcripts | | SARS-CoV-2的nsp1蛋白介导了对哺乳动物翻译的广泛抑制。 | Gen, R. | PDF | N/A | SARS-CoV-2 nsp1 mediates broad inhibition of translation in mammals |

BioRxiv 2025-01-14 Papers

标题	作者	PDF链接	代码仓库	Title
小细胞肺癌亚型分析利用血浆中的游离核小体	Fialkoff, G.	PDF	N/A	Subtyping of Small Cell Lung Cancer using plasma cell-free nucleosomes
不确定性、相关性和学习之间的相互作用影响了听觉分类。	Sheth, J.	PDF	N/A	The interplay of uncertainty, relevance and learning influences auditory categorization
骨膜骨骼干细胞在受伤后可以迁移到骨髓中并支持造血功能。	Marchand, T.	PDF	N/A	Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury
BNST信号和BNST CRF在恐惧处理中的性别差异：对不可预测威胁在持续恐惧中的影响	Hon, O. J.	PDF	N/A	Sex Differences in BNST Signaling and BNST CRF in Fear Processing: Implications for Unpredictable Threat in Sustained Fear
生命之树中转录错误率的狭窄范围	Li, W.	PDF	N/A	A Narrow Range of Transcript-error Rates Across the Tree of Life
挪威云杉（Picea abies）的高辐射敏感性是由于其在保护、修复和应激反应方面的动员不如耐辐射的拟南芥（Arabidopsis thaliana）全面所致。	Bhattacharjee, P.	PDF	N/A	High radiosensitivity in Norway spruce (Picea abies) is rendered by less comprehensive mobilisation of protection, repair and stress responses compared to the radiotolerant Arabidopsis thaliana
大豆初生细胞壁纤维素合酶的结构、功能与组装	Ho, R.	PDF	N/A	Structure, function and assembly of soybean primary cell wall cellulose synthases
对有无静水压力条件下上皮类器官中腔体成核和融合的通用比较	Lu, L.	PDF	N/A	Generic comparison of lumen nucleation and fusion in epithelial organoids with and without hydrostatic pressure
大肠杆菌在失去营养后的最初几个小时内，通过显著重塑其蛋白质组来为饥饿做准备。	Gervais, T.	PDF	N/A	E. coli prepares for starvation by dramatically remodeling its proteome in the first hours after loss of nutrients
基于生物物理学的蛋白质语言模型用于蛋白质工程	Gelman, S.	PDF	N/A	Biophysics-based protein language models for protein engineering
基于微管的成核作用导致植物皮层阵列对细胞几何形状具有高度敏感性。	Saltini, M.	PDF	N/A	Microtubule-based nucleation results in a large sensitivity to cell geometry of the plant cortical array
遗传多样性对跨营养级的生态系统功能的影响与物种多样性相当，但方向相反。	Fargeot, L.	PDF	N/A	Genetic diversity affects ecosystem functions across trophic levels as much as species diversity, but in an opposite direction
在没有六亚基ORC的情况下，原代肝细胞中的DNA复制	Przanowska, R. K.	PDF	N/A	DNA replication in primary hepatocytes without the six-subunit ORC
可分离的记忆调节机制在不同时间尺度上促进恐惧遗忘	Ni, Y.	PDF	N/A	Dissociable memory modulation mechanisms facilitate fear amnesia at different timescales
人类脂肪基质细胞在3D培养系统中向肌腱表型分化，并具有适应性的粘弹性特性。	Horde, M.	PDF	N/A	Human adipose stromal cells differentiate towards a tendon phenotype with adapted visco-elastic properties in a 3D-culture system
增强肿瘤浸润T细胞的专属能量来源	Miller, M. L.	PDF	N/A	Enhancing tumor-infiltrating T cells with an exclusive fuel source
季节性及空间变化对热带太平洋河口至开阔海域浮游植物群落的影响	Tucker, S. J.	PDF	N/A	Seasonal and spatial transitions in phytoplankton assemblages spanning estuarine to open ocean waters of the tropical Pacific
超高剂量口服ω3二十二碳六烯酸（DHA）或二十碳五烯酸（EPA）在MYCN驱动的神经母细胞瘤模型中阻断肿瘤发生	Patel, V.	PDF	N/A	Ultra-high dose oral ω3 docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) block tumorigenesis in a MYCN-driven neuroblastoma model
在强烈波动的环境中，顺序代谢策略的适应优势源于群落相互作用。	Wang, Z.	PDF	N/A	Fitness advantage of sequential metabolic strategies emerges from community interactions in strongly fluctuating environments
季节性及比较证据显示哺乳动物大脑大小可塑性中的适应性基因表达	Thomas, W. R.	PDF	N/A	Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticity
发育和年龄相关的突触消除是由胶质细胞中的Croquemort介导的。	Jay, T. R.	PDF	N/A	Developmental and age-related synapse elimination is mediated by glial Croquemort
细菌性阴道病驱动的宫颈阴道免疫变化，扩展了增加HIV易感性的免疫学假说。	MacLean, F.	PDF	N/A	Bacterial vaginosis-driven changes in cervicovaginal immunity that expand the immunological hypothesis for increased HIV susceptibility
LCSKPOA：通过扩展的lcsk++实现高效且准确的骨架生成，从而支持带状半全局部分序列比对	Weerakoon, M.	PDF	N/A	LCSKPOA: Enabling banded semi-global partial order alignments via efficient and accurate backbone generation through extended lcsk++
在海马记忆任务中，海马下托和CA1位置细胞中任务需求相关放电模式的差异性再激活	Seol, J.-M.	PDF	N/A	Differential Reactivation of Task-Demand-Associated Firing Patterns in Subicular and CA1 Place Cells during a Hippocampal Memory Task
环境背景塑造了丘脑中的空间和时间视觉处理。	Peelman, K.	PDF	N/A	Environmental context sculpts spatial and temporal visual processing in thalamus
MyVivarium：一款基于云端的实验动物群体管理应用程序，具备实时环境感知功能。	Vidva, R.	PDF	N/A	MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing
以下是这段英文的中文翻译：

弧菌属生物膜基质簇和蛋白质的综合基因组与进化分析

这个标题描述了一项研究，旨在对弧菌属（Vibrio genus）中与生物膜基质相关的基因簇和蛋白质进行全面分析，涵盖基因组学和进化生物学的研究方法。 | Yang, Y. | PDF | N/A | Comprehensive Genomic and Evolutionary Analysis of Biofilm Matrix Clusters and Proteins in the Vibrio Genus | | 在PLEKHM2 mRNA解码过程中，程序化的核糖体移码生成了一种持续活跃的介导物，该介导物依赖于驱动蛋白-1（kinesin-1）进行溶酶体运输。 | Loughran, G. | PDF | N/A | Programmed ribosomal frameshifting during PLEKHM2 mRNA decoding generates a constitutively active mediator of kinesin-1-dependent lysosome transport | | 结合剂和单体的价态决定了染色质塌缩和再膨胀的程度。 | Guha, S. | PDF | N/A | Binder and monomer valencies determine the extent of collapse and reswelling of chromatin | | 细胞类型特异性表达FOXP3所需的顺式调控元件和转录因子调控网络 | Umhoefer, J. M. | PDF | N/A | Cis-Regulatory Element and Transcription Factor Circuitry Required for Cell-Type Specific Expression of FOXP3 | | 三碘甲状腺原氨酸和黄芩素对Klotho的双向上调作用：缓解老年BALB/c小鼠的慢性肾脏疾病及其相关并发症 | Mohanty, S. K. | PDF | N/A | Bidirectional Upregulation of Klotho by Triiodothyronine and Baicalein: Mitigating Chronic Kidney Disease and Associated Complications in Aged BALB/c Mice | | 通过眼跳采样进行时空证据积累以实现物体识别 | Zheng, Z. | PDF | N/A | Spatiotemporal evidence accumulation through saccadic sampling for object recognition | | ATG9囊泡是细胞内纳米囊泡的一个亚型。 | Fesenko, M. | PDF | N/A | ATG9 vesicles are a subtype of intracellular nanovesicle | | Na+/K+-ATPase的电生成特性对高度活跃的放电细胞中的计算提出了挑战。 | Weerdmeester, L. | PDF | N/A | The electrogenicity of the Na+/K+-ATPase poses challenges for computation in highly active spiking cells | | 第六层皮质丘脑神经元通过皮质-皮质和皮质-丘脑-皮质通路诱导高频伽马振荡。 | Russo, S. | PDF | N/A | Layer 6 corticothalamic neurons induce high gamma oscillations through cortico-cortical and cortico-thalamo-cortical pathways | | 解码难以理解的声音：低信噪比下的神经语音追踪 | He, X. | PDF | N/A | Decoding the Unintelligible: Neural Speech Tracking in Low Signal-to-Noise Ratios | | 保守的基因组成和独特的系统发育历史是Triturus平衡致死系统背后的“bloopergene”特征。 | de Visser, M. C. | PDF | N/A | Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system | | 分泌型Clever-1调节T细胞反应并影响癌症免疫治疗效果 | Prince, S. | PDF | N/A | Secreted Clever-1 Modulates T Cell Responses and Impacts Cancer Immunotherapy Efficacy | | 解码非模式生物的功能相互作用组与PHILHARMONIC | Sledzieski, S. | PDF | N/A | Decoding the Functional Interactome of Non-Model Organisms with PHILHARMONIC | | 西澳大利亚城市灌木丛火灾后兰花的成败：与其他特性深度融合的响应连续体 | Brundrett, M. C. | PDF | N/A | Orchid losers and winners after fire in West Australian urban bushland: A response continuum deeply integrated with other traits | | 将“Benchmarking unsupervised methods for inferring TCR specificity”翻译成中文是：

“用于推断TCR特异性的无监督方法的基准测试”

其中： - Benchmarking 意为“基准测试”或“性能评估” - unsupervised methods 意为“无监督方法” - inferring 意为“推断” - TCR specificity 意为“TCR特异性”（TCR指T细胞受体）

整句话的意思是评估或比较无监督学习方法在推断T细胞受体（TCR）特异性方面的性能。 | Jouannet, C. | PDF | N/A | Benchmarking unsupervised methods for inferring TCR specificity | | 小脑性伸手共济失调对运动学和动力学需求的敏感性 | Oh, K. | PDF | N/A | Sensitivity of Cerebellar Reaching Ataxia to Kinematic and Dynamic Demands | | DNA复制叉速度在皮质神经发生中起到节奏调节器的作用 | Wang, J. | PDF | N/A | DNA replication fork speed Acts as a Pacer in Cortical Neurogenesis | | 负责语言产生的布洛卡区受到肺功能的调节。 | Cao, S. | PDF | N/A | Broca's area responsible for speech production is regulated by lung functions | | 跑步鞋堆叠高度在不同跑步速度下对跑步风格和稳定性的影响 | Kettner, C. | PDF | N/A | The effects of running shoe stack height on running style and stability during level running at different running speeds | | 测试大黄蜂中的峰终法则：当最终奖励令人失望时，缺乏对更高奖励序列的偏好 | Armand, M. | PDF | N/A | Testing the peak-end rule in bumblebees: lack of preference for a higher-reward sequence when the final reward is disappointing | | 识别基孔肯雅病毒nsP2 ATP酶抑制剂 | Navarro, H. | PDF | N/A | Identification of Inhibitors of Chikungunya virus nsP2 ATPase | | 自闭症相关蛋白在纤毛处的汇聚 | Kostyanovskaya, E. | PDF | N/A | Convergence of autism proteins at the cilium | | Pol II降解独立于转录丧失激活细胞死亡。 | Harper, N. W. | PDF | N/A | Pol II degradation activates cell death independently from the loss of transcription | | 数据驱动的突触分类揭示了谷氨酸受体多样性的逻辑 | Micheva, K. D. | PDF | N/A | Data-driven synapse classification reveals a logic of glutamate receptor diversity | | 单个神经元的多样性支持视觉皮层通路中区域功能的专门化 | Feyerabend, M. | PDF | N/A | Single neuron diversity supports area functional specialization along the visual cortical pathways | | 撤回：生物学黎明时期的结构酶学、系统发育学、分化与符号反身性 | Carter, C. W. | PDF | N/A | WITHDRAWN: Structural Enzymology, Phylogenetics, Differentiation, and Symbolic Reflexivity at the Dawn of Biology | | 收集、检测和处理纵向光照数据中的非佩戴间隔 | Guidolin, C. | PDF | N/A | Collecting, detecting and handling non-wear intervals in longitudinal light exposure data | | 齿状回为高效的空间导航提供了灵活性。 | Soldi, N. | PDF | N/A | The dentate gyrus provides flexibility for efficient spatial navigation | | 跟随机器人的引导：在运动学习人机交互任务中通过脑电图预测人类和机器人运动 | Chatterjee, T. | PDF | N/A | Following the Robot's Lead: Predicting Human and Robot Movement from EEG in a Motor Learning HRI Task | | 对蓖麻蚕（学名：Samia ricini）的基因组组装进行了重大更新。 | Lee, J. | PDF | N/A | A major update of the genome assembly of Eri silkmoth, Samia ricini. | | grepq：一个用 Rust 编写的应用程序，能够通过将序列与一组正则表达式进行匹配来快速过滤 FASTQ 文件。 | Crosbie, N. D. | PDF | N/A | grepq: A Rust application that quickly filters FASTQ files by matching sequences to a set of regular expressions | | VZV gE通过Midnolin-蛋白酶体途径促进STING降解，从而抑制cGAS-STING信号通路 | Chen, L. | PDF | N/A | VZV gE Promotes STING Degradation via Midnolin-Proteasome Pathway to Inhibit cGAS-STING Signaling | | 漱口水暴露后唾液微生物组龋齿潜力的个体间差异 | Mermans, F. | PDF | N/A | Interindividual differences in caries potential of the salivary microbiome after mouthwash exposure | | 氯霉素诱导的枯草芽孢杆菌暂时表现出对多种抗生素的耐药性，包括糖肽类抗生素腐草霉素和博莱霉素。 | LaBonte, S. A. | PDF | N/A | Chloramphenicol-mobilized Bacillus subtilis transiently expresses resistance to multiple antibiotics, including the glycopeptides phleomycin and bleomycin | | 一套预组装的、基于pET28b的Golden Gate载体，用于高效的蛋白质工程和表达。 | Gaur, D. | PDF | N/A | A suite of pre-assembled, pET28b-based Golden Gate vectors for efficient protein engineering and expression | | 两种运输途径用于基于胎球蛋白A的矿物质复合物在成骨基质矿化中的作用 | Schaart, J. M. | PDF | N/A | Two Transport Routes for Fetuin-A-based Mineral Complexes in Osteogenic Matrix Mineralization | | 以下是这段英文的中文翻译：

水疱性口炎病毒糖蛋白G的单独结构及其与中和抗体复合物的结构

翻译解释： 1. "Structures of" 翻译为 "结构" 2. "vesicular stomatitis virus" 翻译为 "水疱性口炎病毒" 3. "glycoprotein G" 翻译为 "糖蛋白G" 4. "alone" 翻译为 "单独" 5. "in complex with" 翻译为 "与...复合物" 6. "a neutralizing antibody" 翻译为 "中和抗体"

一种通过重写γ-珠蛋白启动子并重新激活胎儿血红蛋白来治疗镰状细胞病的精准编辑策略。

翻译说明： 1. "prime editing" 翻译为“精准编辑”，这是一种新型的基因编辑技术。 2. "γ-globin promoters" 翻译为“γ-珠蛋白启动子”，γ-珠蛋白是胎儿血红蛋白的组成部分。 3. "reactivate fetal hemoglobin" 翻译为“重新激活胎儿血红蛋白”，这是治疗镰状细胞病的一种潜在方法。 4. "sickle cell disease" 翻译为“镰状细胞病”，这是一种遗传性血液疾病。

这个翻译准确地传达了原文的科学内容和技术目标。 | Chalumeau, A. | PDF | N/A | A prime editing strategy to rewrite the γ-globin promoters and reactivate fetal hemoglobin for sickle cell disease | | miR-379-3p通过调控嘧啶能受体、线粒体应激和干扰素反应来对抗癌症恶病质。 | Borja-Gonzalez, M. | PDF | N/A | miR-379-3p counteracts cancer cachexia through regulation of pyrimidinergic receptor, mitochondrial stress and interferon response. | | 雄性鸭子的求偶鸣叫：鸣管气囊的频谱组成与共振 | Mishkind, D. | PDF | N/A | Courtship vocalizations in male ducks: spectral composition and resonance of the syringeal bulla | | GPR15LG与CXCR4结合，并协同调节CXCL12诱导的细胞信号传导和迁移。 | Albers, D. | PDF | N/A | GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migration | | 稀疏交互作用建模能够在生物银行规模的研究中快速检测全基因组上位性。 | Stamp, J. | PDF | N/A | Sparse modeling of interactions enables fast detection of genome-wide epistasis in biobank-scale studies | | 通过对驱动复杂小眼症的调控变异的研究，深入探讨FOXE3转录网络及其疾病机制 | Plaisancie, J. | PDF | N/A | Insights into the FOXE3 Transcriptional Network and Disease Mechanisms from the Investigation of a Regulatory Variant Driving Complex Microphthalmia | | 显微镜节点：使用Blender进行多功能3D显微镜可视化 | Gros, O. | PDF | N/A | Microscopy Nodes: versatile 3D microscopy visualization with Blender | | 开发ERAF-AI：人工智能早期研究评估框架 | Falvo, D. | PDF | N/A | Developing ERAF-AI: An Early-stage ResearchAssessment Framework for Artificial Intelligence | | 分泌的福氏耐格里阿米巴小RNA作为原发性阿米巴脑膜脑炎诊断的生物标志物 | Russell, A. C. | PDF | N/A | Secreted small RNAs of Naegleria fowleri as biomarkers for diagnosis of primary amoebic meningoencephalitis | | 整合显式可靠性以做出最优选择：可信度对决策和元决策的影响 | Ota, K. | PDF | N/A | Integrating explicit reliability for optimal choices: effect of trustworthiness on decisions and metadecisions | | FGFR1抑制可防止与胶质母细胞瘤治疗抵抗相关的代谢适应 | Duran, R. V. | PDF | N/A | FGFR1 inhibition prevents metabolic adaptation associated with therapy resistance in glioblastoma | | DUSP12通过调节ZPR9促进细胞周期进程并保护细胞免受细胞死亡。 | Abdusamad, M. | PDF | N/A | DUSP12 promotes cell cycle progression and protects cells from cell death by regulating ZPR9 | | 弱且可调的黏附-离合器机制驱动快速细胞迁移和胶质母细胞瘤运动 | Baba, K. | PDF | N/A | Weak and tunable adhesion-clutch drives rapid cell migration and glioblastoma motility | | 弱且可调的黏附-离合器机制驱动快速细胞迁移和胶质母细胞瘤运动 | Baba, K. | PDF | N/A | Weak and tunable adhesion-clutch drives rapid cell migration and glioblastoma motility | | 有丝分裂驱动蛋白HSET的功能调控通过纤毛内运输蛋白实现。 | Guesdon, A. | PDF | N/A | Functional regulation of the mitotic kinesin HSET by Intraflagellar Transport proteins. | | 利用多尺度建模方法对α-突触核蛋白液态凝聚体和纤维状聚集体的肽抑制剂进行理性设计 | Ekambaram, S. | PDF | N/A | Rationale design of peptide inhibitors for α-Synuclein liquid condensates and fibrillar aggregates using multiscale modelling approach | | 突触中几何形状对蛋白质迁移的影响 | Dannenberg, S. | PDF | N/A | Geometry effects on protein mobility in a synapse | | 在急性环境挑战下斑马鱼尾部神经分泌系统中激素基因表达的变化 | Bichon, B. | PDF | N/A | Hormonal gene expression changes in the zebrafish caudal neurosecretory system under acute environmental challenges | | 效应器触发的处理体形成通过内质网应激反应和自噬在细菌感染时减弱宿主翻译 | Gonzalez-Fuente, M. | PDF | N/A | Effector-triggered processing body formation attenuates host translation via ER stress responses and autophagy upon bacterial infection | | 蕨类植物Ceratopteris richardii的U6启动子及表达Cas9内切酶的植株作为高效基因组编辑工具 | Schulz, R. | PDF | N/A | Ceratopteris richardii U6 promoters and plants expressing Cas9 endonuclease as tools for efficient genome editing in a fern | | 金盏花（Calendula officinalis）中抗炎三萜类化合物的生物合成与生物活性 | Golubova, D. | PDF | N/A | Biosynthesis and Bioactivity of Anti-Inflammatory Triterpenoids in Calendula officinalis (pot marigold) | | 四倍体马铃薯品种Desiree的单倍型解析基因组组装 | Godec, T. | PDF | N/A | Haplotype-resolved genome assembly of the tetraploid potato cultivar Desiree | | 形成冬季菌根的细根内生菌 | Sentoku, T. | PDF | N/A | Fine root endophytes forming winter mycorrhiza | | 对秀丽隐杆线虫（Caenorhabditis elegans）神经元网络的符号基序分析揭示了正前馈和负反馈环路的存在。 | Szilagyi, G. S. | PDF | N/A | Signed motif analysis of the Caenorhabditis elegans neuronal network reveals positive feedforward and negative feedback loops | | 将这段翻译成中文为：感觉运动皮层中功能性ALS病理的个体化表型分析 | Kalyani, A. | PDF | N/A | Individualized Phenotyping of Functional ALS Pathology in Sensorimotor Cortex | | 《人类大脑形态相关的血浆代谢标志物图谱》 | van der Meer, D. | PDF | N/A | Atlas of plasma metabolic markers linked to human brain morphology | | 白细胞介素-34和单核吞噬细胞对碎片的清除驱动斑马鱼视网膜色素上皮的再生 | Leach, L. L. | PDF | N/A | Interleukin-34 and debris clearance by mononuclear phagocytes drive retinal pigment epithelium regeneration in zebrafish | | 在嗜热四膜虫中，一种与溶酶体相关细胞器（LRO）生物发生所需的V-ATPase复合物，在LRO成熟过程中会解离。 | Pradhan, A. | PDF | N/A | A V-ATPase complex, required for biogenesis of a lysosome-related organelle (LRO) in Tetrahymena thermophila, disassembles during LRO maturation | | 沉默子元件中的遗传变异影响人类血细胞特征 | Tan, M. | PDF | N/A | Genetic variants within silencer elements contribute to human blood cell traits | | 氯仿从老化细胞和果蝇DJ-1突变体中释放 | Issitt, T. | PDF | N/A | Chloroform release from ageing cells and Drosophila DJ-1 mutants | | 使用机器学习模型评估微小RNA的遗传调控因子 | Cihan, M. | PDF | N/A | Evaluating Genetic Regulators of MicroRNAs Using Machine Learning Models | | 评估四种ECM相关基因在结直肠癌复发和转移中的预后价值 | Avcıoglu, B. S. D. | PDF | N/A | Evaluation of the Prognostic Value of Four ECM-Associated Genes in Recurrence and Metastasis of Colorectal Cancer | | 在蕨类植物Ceratopteris richardii中过量表达MADS-box基因CRM3会影响孢子体的发育。 | Schulz, R. | PDF | N/A | Overexpression of the MADS-box gene CRM3 in the fern Ceratopteris richardii affects sporophyte development | | 为六倍体甘薯及其二倍体野生近缘种构建参考质量的NLRome | Parada-Rojas, C. H. | PDF | N/A | A reference-quality NLRome for the hexaploid sweetpotato and diploid wild relatives | | 较低的慢波睡眠和快速眼动睡眠与阿尔茨海默病易感区域的脑萎缩有关。 | Cho, G. | PDF | N/A | Lower slow wave sleep and rapid eye-movement sleep are associated with brain atrophy of AD-vulnerable regions | | 变暖和降雨量增加会降低熊蜂蜂王的健康状况 | Archer, C. R. | PDF | N/A | WARMING AND INCREASED RAINFALL REDUCE BUMBLEBEE QUEEN FITNESS | | 利用抗体库数据和机器学习进行抗体亲和力工程 | Erlach, L. | PDF | N/A | Antibody affinity engineering using antibody repertoire data and machine learning | | easyEWAS：一个灵活且用户友好的R包，用于全表观基因组关联研究 | Wang, Y. | PDF | N/A | easyEWAS: a flexible and user-friendly R package for Epigenome-Wide Association Study | | RNA测序揭示了调控TNFα刺激下牙髓干细胞向成牙本质细胞样分化的关键因素 | Irfan, M. | PDF | N/A | RNA sequencing reveals key factors modulating TNFa-stimulated odontoblast-like differentiation of dental pulp stem cells | | 冷冻电镜捕捉到了LIS1激活动力蛋白的早期中间步骤 | Nguyen, K. H. V. | PDF | N/A | Cryo-EM captures early intermediate steps in dynein activation by LIS1 | | 通过冷冻电镜和分子动力学模拟揭示的血管紧张素-I转换酶的二聚化和动态特性 | Tang, W.-J. | PDF | N/A | Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations | | 通过冷冻电镜和分子动力学模拟揭示的血管紧张素-I转换酶的二聚化及动态特性 | mancl, j. M. | PDF | N/A | Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryoEM and MD simulations | | 蛋白质的稳定性由单一位点的偏好决定，而不是成对协方差。 | Sternke, M. | PDF | N/A | Protein stability is determined by single-site bias rather than pairwise covariance | | 开源3D荧光显微镜主动样本稳定技术 | Patil, S. | PDF | N/A | Open-Source 3D Active Sample Stabilization for Fluorescence Microscopy | | 基于图像的纳米级三维主动样品稳定技术用于光学显微镜 | Vorlaufer, J. | PDF | N/A | Image-based 3D active sample stabilization on the nanometer scale for optical microscopy | | 药物诱导的核CTSL（nCTSL）在癌症DNA损伤反应中的作用及其治疗意义 | Thirusangu, P. | PDF | N/A | Role of drug induced nuclear CTSL (nCTSL) in DNA damage response in cancer- therapeutic implications | | 在大西洋鲑鱼循环水养殖系统废水中培养的三角褐指藻（Phaeodactylum tricornutum）的生物量生产、磷利用效率和脂肪酸组成 | Borg-Stoveland, S. | PDF | N/A | Biomass Production, Phosphorus Use Efficiency, and Fatty Acid Composition in Phaeodactylum tricornutum Cultivated in Wastewater from an Atlantic Salmon Recirculating Aquaculture System | | 一种具有集成DNA自我复制和膜生物合成的合成细胞 | Restrepo Sierra, A. M. | PDF | N/A | A synthetic cell with integrated DNA self-replication and membrane biosynthesis | | 缺氧诱导因子2α在肠道蠕虫感染期间促进保护性Th2细胞反应 | Labuda, J. C. | PDF | N/A | Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection | | 通过全息加热显微镜实现的时空温度控制揭示了细胞的热敏钙信号传导机制。 | Oyama, K. | PDF | N/A | Spatiotemporal temperature control by holographic heating microscopy unveils cellular thermosensitive calcium signaling | | 将1400万种虚拟异喹啉类化合物与μ和κ阿片受体进行对接，揭示了具有减少戒断效应的双重拮抗剂-反向激动剂。 | Vigneron, S. F. | PDF | N/A | Docking 14 million virtual isoquinuclidines against the mu and kappa opioid receptors reveals dual antagonists-inverse agonists with reduced withdrawal effects | | BicD和MAP7通过互补机制协作激活同源二聚体果蝇驱动蛋白-1（kinesin-1）。 | Ali, M. Y. | PDF | N/A | BicD and MAP7 collaborate to activate homodimeric Drosophila kinesin-1 by complementary mechanisms | | 整合技术用于细胞外颗粒分离和单颗粒多参数表征，以追踪从组织到生物流体的癌症生物标志物 | Nguyen, K. T. | PDF | N/A | Integrated Techniques for Extracellular Particle Separation and Single-Particle Multiparametric Characterization to Track Cancer Biomarkers from Tissue to Biofluids | | 一种新型小鼠尾部模型用于不同剂量局部照射后辐射性皮肤损伤的研究 | Wang, T. | PDF | N/A | A novel murine tail model for radiation-induced skin injury following localized irradiation at varying doses | | 突变的p.H222P A型核纤层蛋白在患者来源的心肌细胞和扩张型心肌病小鼠模型中均驱动Loxl2介导的细胞外基质重塑 | Kervella, M. | PDF | N/A | The Mutated p.H222P A-type Lamins Drive Loxl2-Mediated Extracellular Matrix Remodeling in Both Patient-Derived Cardiomyocytes and Mouse Models of Dilated Cardiomyopathy | | “自然价值视角”量表：一个经过验证的量表，用于从变革的角度衡量未来自然的多元价值视角。 | Buijs, A. | PDF | N/A | The "value perspectives of nature" scale: A validated scale to measure plural value perspectives of future nature from a transformative angle. | | 混合的正负反馈回路驱动多样的单细胞基因表达动态 | Loman, T. E. | PDF | N/A | Mixed positive and negative feedback loops drive diverse single-cell gene expression dynamics | | 中性蛋白质进化中的固守性与偶然性及上位效应 | Schmelkin, L. | PDF | N/A | Entrenchment and contingency in neutral protein evolution with epistasis | | 长读长低通测序用于高分辨率性状定位 | Lee, K. C. | PDF | N/A | Long-Read Low-Pass Sequencing for High-Resolution Trait Mapping | | 实时彩色血流映射超声微机器人 | Dillinger, C. | PDF | N/A | Real-time Color Flow Mapping of Ultrasound Microrobots | | 多核非血红素铁依赖氧化酶：其底物、伴侣蛋白及生物合成基因簇的概览 | Antoine, R. | PDF | N/A | Multinuclear non-heme iron dependent oxidative enzymes: Landscape of their substrates, partner proteins and biosynthetic gene clusters | | Cleanet：基于蛋白质表达模式的细胞计数数据中稳健的双峰检测 | Ionita, M. | PDF | N/A | Cleanet: robust doublet detection in cytometry data based on protein expression patterns | | 通过捕捉键微调材料特性 | Rabbi, M. F. | PDF | N/A | Fine-Tuning of Material Properties via Catch Bonds | | MYCN mRNA中的非编码RNA元件是致癌作用的强效自主驱动因素。 | Powers, J. | PDF | N/A | Noncoding RNA elements within MYCN mRNA are potent autonomous drivers of oncogenesis. | | 细胞外基质驱动鸟苷酸的产生，并保护胰腺癌细胞免受奥沙利铂诱导的DNA损伤。 | Efthymiou, G. | PDF | N/A | The extracellular matrix drives guanylate production and protects pancreatic cancer cells from oxaliplatin-induced DNA damage. | | 在TP53野生型和突变型癌细胞中，使用DRx-098D靶向破坏MDM2同源二聚体和异源二聚体 | Cooke, S. F. | PDF | N/A | Targeting MDM2 homodimer and heterodimer disruption with DRx-098D in TP53 wild-type and mutant cancer cells | | 长期培养的患者来源卵巢癌类器官高度模拟了原始肿瘤及其临床反应。 | Thorel, L. | PDF | N/A | Long-term patient-derived ovarian cancer organoids closely recapitulate tumor of origin and clinical response | | ATP敏感的P2X5亚型：跨物种功能的重新评估 | Yang, X.-N. | PDF | N/A | ATP-sensitive isoforms of P2X5: A reevaluation of its function across species | | 分泌型氧化还原传感器roGFP2-Orp1揭示了植物质外体中的氧化动态。 | Ingelfinger, J. | PDF | N/A | The secreted redox sensor roGFP2-Orp1 reveals oxidative dynamics in the plant apoplast | | TrueSpot：一种用于量化荧光成像中信号点（puncta）的强大自动化工具 | Hospelhorn, B. G. | PDF | N/A | TrueSpot: A robust automated tool for quantifying signal puncta in fluorescent imaging | | 优化dsRNA序列以用于害虫控制和研究中的RNA干扰技术，利用dsRIP网络平台 | Cedden, D. | PDF | N/A | Optimizing dsRNA sequences for RNAi in pest control and research with the dsRIP Web-Platform | | CD2表达与人类T细胞中的干性相关因子和耗竭相关因子共同调控。 | Demetriou, P. | PDF | N/A | CD2 expression is co-regulated with stemness- and exhaustion-associated factors in human T cells | | 白细胞介素10在鸟类中控制着耐受性、病原体清除和免疫病理学之间的平衡。 | Meunier, D. | PDF | N/A | Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds. | | 组织驻留的骨骼肌巨噬细胞促进正常衰老中病毒性肺炎引起的肌肉减少症的恢复。 | Runyan, C. E. | PDF | N/A | Tissue-resident skeletal muscle macrophages promote recovery from viral pneumonia-induced sarcopenia in normal aging. | | 抗生素耐药性大肠杆菌在沃勒溪（Waller Creek）中很常见，这是一条长期受到粪便细菌污染的城区水道。 | Olivera Perez, L. | PDF | N/A | Antibiotic Resistant E. Coli are Common in Waller Creek, an Urban Waterway Chronically Contaminated with Fecal Bacteria | | 在进行基于特征的植物-传粉者相互作用预测时，物候更替是一个重要因素。 | Cantwell-Jones, A. R. | PDF | N/A | Phenological turnover matters when making trait-based predictions of plant-pollinator interactions | | 海拔和小气候温度对地中海山脉蝴蝶-花卉相互作用网络的影响 | Alamo, M. | PDF | N/A | Effects of elevation and microclimatic temperatures on butterfly-flower interaction networks in a Mediterranean mountain range | | 一张新的南满混合森林地图有助于估算其保护区域的面积。 | Dzizyurova, V. | PDF | N/A | A new map of South Manchurian mixed forests facilitates the estimation of their area for conservation purposes | | 较大的幼体海七鳃鳗（Petromyzon marinus）在暴露于杀七鳃鳗剂3-三氟甲基-4-硝基苯酚时，具有更长的存活时间。 | Nalesnik, A. M. | PDF | N/A | Larger larval sea lamprey (Petromyzon marinus) have longer survival times when exposed to the lampricide 3-trifluoromethyl-4-nitrophenol | | 对扁形动物毒素进化及其在陆地化过程中的作用进行蛋白质组学与转录组学联合研究 | Garcia-Vernet, R. | PDF | N/A | A proteo-transcriptomic investigation of toxin evolution in planarians and their role in flatworm terrestrialization | | 飞翅的宏观进化沿着发育路径中阻力最小的方向进行。 | Rohner, P. T. | PDF | N/A | Macroevolution of fly wings proceeds along developmental lines of least resistance | | 对真菌界中支撑转座子防御系统的遗传因素进行系统性筛选 | Badet, T. | PDF | N/A | A systematic screen for genetic factors underpinning transposon defense systems across the fungal kingdom | | 遗传变异在塑造衰老果蝇对饮食的表型反应中的作用 | Bak, N. K. | PDF | N/A | The Role of Genetic Variation in Shaping Phenotypic Responses to Diet in Aging Drosophila melanogaster | | 一种基于谱系的方法，用于揭示混合群体中特定祖先的结构 | Tang, J. | PDF | N/A | A genealogy-based approach for revealing ancestry-specific structures in admixed populations | | 一个鼠类结构变异数据库使得自发性鼠类淋巴瘤的遗传结构得以被表征 | Ren, W. | PDF | N/A | A Murine Database of Structural Variants Enables the Genetic Architecture of a Spontaneous Murine Lymphoma to be Characterized | | 生理相关的口腔微生物-宿主相互作用共培养模型 | Pang, Z. | PDF | N/A | Physiologically Relevant Coculture Model for Oral Microbial-Host Interactions | | 对用于骨骼再生的体外工程化但无细胞的人类组织移植物进行临床前验证 | Garcia Garcia, A. | PDF | N/A | Pre-clinical validation of in vitro engineered but cell-free human tissue grafts for skeletal regeneration | | 使用SHAPES评估生成模型对蛋白质结构的覆盖情况 | Lu, T. | PDF | N/A | Assessing Generative Model Coverage of Protein Structures with SHAPES | | 实时同步监测细菌培养物中的多种分析物 | Fink, M. M. | PDF | N/A | Real-time simultaneous monitoring of multiple analytes in bacterial cultures | | 高通量黏液微流变学用于表型分析和疾病建模 | Ling, F. | PDF | N/A | High-throughput Mucus Microrheology for Phenotyping and Disease Modeling | | 全球栖息地中病毒组编码的人类益生基因与致病基因的共存 | Qian, M. | PDF | N/A | Coexistence of Virome-Encoded Human Probiotic Genes and Pathogenic Genes in Global Habitats | | CellUntangler：利用深度生成模型分离单细胞数据中的不同生物信号 | Chen, S. | PDF | N/A | CellUntangler: separating distinct biological signals in single-cell data with deep generative models | | CryoNeRF：使用神经辐射场重建同质和异质的冷冻电镜结构 | Qu, H. | PDF | N/A | CryoNeRF: reconstruction of homogeneous and heterogeneous cryo-EM structures using neural radiance field | | Rosace-AA：通过氨基酸替换和位置特异性洞察增强深度突变扫描数据的解释 | Rao, J. | PDF | N/A | Rosace-AA: Enhancing Interpretation of Deep Mutational Scanning Data with Amino Acid Substitution and Position-Specific Insights | | scValue：基于价值的大规模单细胞转录组数据子采样 | Huang, L. | PDF | N/A | scValue: value-based subsampling of large-scale single-cell transcriptomic data | | 低复杂度连接器作为DNAJB分子伴侣中分子内和分子间相互作用的驱动因素 | Hobbs, B. | PDF | N/A | A low-complexity linker as a driver of intra- and intermolecular interactions in DNAJB chaperones | | 通过可变结合模式，广泛的全氟烷基物质（PFAS）能够与脂肪酸结合蛋白4（FABP4）结合。 | Birchfield, A. S. | PDF | N/A | Broad PFAS binding with fatty acid binding protein 4 is enabled by variable binding modes. | | 光诱导的果蝇隐花色素构象转换及其磁敏感性 | Chandler, S. A. | PDF | N/A | Light-induced conformational switching and magnetic sensitivity of Drosophila cryptochrome | | 具有Wnt1调节活性的抗癌合成芳基磺酰胺类药物 | Gutti, M. | PDF | N/A | Anticancer synthetic arylsulfonamides with Wnt1-modulating activity | | 由微外显子跳跃定义的神经元细胞粘附分子（NRCAM）变体是高级别胶质瘤中一种重要的、抗原性独特且可靶向的表面蛋白质形式。 | Sehgal, P. | PDF | N/A | Neuronal cell adhesion molecule (NRCAM) variant defined by microexon skipping is an essential, antigenically distinct, and targetable surface proteoform in high-grade glioma | | 通过有效靶向PI3K激酶，绕过Nrf2过度激活的头颈癌对顺铂的耐药性 | Sandulache, V. C. | PDF | N/A | Bypassing cisplatin resistance in Nrf2 hyperactivated head and neck cancer through effective PI3Kinase targeting | | 高效能新型多装甲IL13Rα2 CAR-T细胞颠覆了胶质母细胞瘤的免疫抑制微环境 | Mangolini, M. | PDF | N/A | Highly potent novel multi-armoured IL13Rα2 CAR-T subverts the immunosuppressive microenvironment of Glioblastoma | | 抑制谷氨酰胺代谢通过重塑巨噬细胞免疫微环境抑制肿瘤进展 | Li, T. | PDF | N/A | Inhibition of Glutamine Metabolism Suppresses Tumor Progression through Remodeling of the Macrophage Immune Microenvironment | | 反复出现的致癌性ZC3H18突变稳定了内源性逆转录病毒RNA | Tanu, T. | PDF | N/A | Recurrent oncogenic ZC3H18 mutations stabilize endogenous retroviral RNA | | 小分子促进内源性脂滴积累驱动溶酶体自噬 | Vechalapu, S. K. | PDF | N/A | Small molecule promoters of endogenous lipid droplet accumulation drive lysophagy | | 全球板块模型的选择会影响纬度生物多样性梯度重建的结果。 | Jones, L. A. | PDF | N/A | Global plate model choice impacts reconstructions of the latitudinal biodiversity gradient | | 以下是这段文字的中文翻译：

裸盖菇素对大鼠的年龄和发情周期依赖性影响

翻译说明： - "Age-dependent" 翻译为 "年龄依赖性"，表示效果随年龄变化。 - "estrous-dependent" 翻译为 "发情周期依赖性"，表示效果与大鼠的发情周期有关。 - "psilocybin" 是裸盖菇素，一种具有精神活性的化合物。 - "rats" 翻译为 "大鼠"，是常用的实验动物。

"陆地节肢动物在扩散、生活史和热生态位方面表现出一致的相关性。"

翻译解释： - "Consistent covariation" 翻译为 "一致的相关性" - "dispersal" 翻译为 "扩散" - "life history" 翻译为 "生活史" - "thermal niches" 翻译为 "热生态位" - "across terrestrial arthropods" 翻译为 "在陆地节肢动物中"

这个标题的中文翻译尽量保持了原文的专业性和准确性，同时确保语言流畅。标题中的关键术语如“Database”（数据库）、“Permeating through Time, Space, and Medicine”（穿越时空与医学）、“sequence, structure, and clinical compilation and comparison”（序列、结构及临床汇编与比较）以及“transmembrane amino acids in VGL ion channels”（VGL离子通道跨膜氨基酸）都得到了恰当的翻译。 | Yeh, F. | PDF | N/A | Database Permeating through Time, Space, and Medicine: A sequence, structure, and clinical compilation and comparison of transmembrane amino acids in VGL ion channels | | MISO：微流控蛋白质分离技术使得从单个细胞群体中确定单颗粒冷冻电镜结构成为可能。 | Eluru, G. | PDF | N/A | MISO: Microfluidic protein isolation enables single particle cryo-EM structure determination from a single cell colony | | ANGPTL6变异导致小鼠脑血管功能障碍并增加颅内动脉瘤的易感性 | Baron-Menguy, C. | PDF | N/A | ANGPTL6 variant induces cerebral vascular dysfunction and predisposes to intracranial aneurysm in mice | | 以下是这段英文的中文翻译：

为蚤蝇（Megaselia abdita）提供的基因组资源：一种用于果蝇比较发育研究的模式生物

翻译说明： - "Genomic Resources" 翻译为“基因组资源”，指的是与基因组相关的数据、工具或信息。 - "Scuttle Fly" 是“蚤蝇”的英文名称，属于双翅目昆虫。 - "Megaselia abdita" 是蚤蝇的学名，通常直接保留拉丁名。 - "Model Organism" 翻译为“模式生物”，指在科学研究中被广泛使用的代表性生物。 - "Comparative Developmental Studies" 翻译为“比较发育研究”，指通过比较不同物种的发育过程来研究其异同。 - "Flies" 翻译为“果蝇”或“蝇类”，这里泛指双翅目昆虫。

淀粉样纤维组装的结构基础：由主细胞信号调节因子人类受体相互作用蛋白激酶1介导

这个标题描述了一项研究，旨在揭示人类受体相互作用蛋白激酶1（RIPK1）在淀粉样纤维组装中的结构机制。RIPK1是一种关键的细胞信号调节因子，参与多种细胞过程，包括炎症和细胞死亡。淀粉样纤维是一种与多种神经退行性疾病（如阿尔茨海默病）相关的蛋白质聚集体。研究其组装机制对于理解疾病的发生和开发潜在治疗方法具有重要意义。 | Polonio, P. | PDF | N/A | Structural Basis for the Assembly of Amyloid Fibrils by the Master Cell-Signaling Regulator Human Receptor-Interacting Protein Kinase 1 | | 肝脏淋巴功能障碍作为纤维化和肝硬化进展的驱动因素 | Jeong, J. | PDF | N/A | Liver Lymphatic Dysfunction as a Driver of Fibrosis and Cirrhosis Progression | | 在线GPCR药物发现资源 | Caroli, J. | PDF | N/A | An online GPCR drug discovery resource | | 在大鼠适应运动训练前后，骨骼肌线粒体中均含有核编码的RNA种类。 | Silver, J. L. | PDF | N/A | Skeletal muscle mitochondria contain nuclear-encoded RNA species prior to and following adaptation to exercise training in rats | | 过度表达TEMPRANILLO样蛋白促进杨树的内休眠解除 | Gomez-Soto, D. | PDF | N/A | OVEREXPRESSION OF TEMPRANILLO-LIKE PROTEINS PROMOTES ENDORMANCY RELEASE IN POPLAR | | 关于“Candidatus Accumulibacter”双底物生长的代谢影响 | Paez-Watson, T. | PDF | N/A | Metabolic implications for dual substrate growth in "Candidatus Accumulibacter" | | 一项整合系统生物学的方法确立了精氨酸生物合成作为白色念珠菌在宿主感染期间的代谢弱点。 | Chakraborty, S. | PDF | N/A | An integrated systems biology approach establishes arginine biosynthesis as a metabolic weakness in Candida albicans during host infection | | 一种在SPR生物传感器芯片上生产数千种单链抗体变体的方法，用于测量目标结合动力学并深入表征抗体结合位点。 | Cook, R. L. | PDF | N/A | An approach to produce thousands of single-chain antibody variants on a SPR biosensor chip for measuring target binding kinetics and for deep characterization of antibody paratopes | | 在CASPR2抗体脑炎中，宽松的中枢耐受性加上缺陷的外周检查点使得致病性记忆B细胞得以存在。 | Sun, B. | PDF | N/A | Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis | | 在CASPR2抗体脑炎中，宽松的中枢耐受加上有缺陷的外周检查点使得致病性记忆B细胞得以存在。 | Sun, B. | PDF | N/A | Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis | | 生成具有生成性变压器的T细胞受体同源表位序列 | Ma, M. | PDF | N/A | Generating cognate epitope sequences of T-cell receptors with a generative transformer | | 极端高多样性条形码HIV文库使得单细胞多组学分析病毒表达和命运决定成为可能。 | Zhang, T.-h. | PDF | N/A | Extreme high-diversity barcoded HIV library enables single cell multi-omics analysis of viral expression and fate determination | | 构建机械生物学图谱：在五种原代人类细胞类型中对2418种激酶抑制剂进行高通量收缩性筛选，揭示了相关细胞类型之间的选择性差异反应 | Shpak, A. | PDF | N/A | Building an atlas of mechanobiology: high-throughput contractility screen of 2418 kinase inhibitors in five primary human cell types reveals selective divergent responses among related cell types | | 单壁碳纳米管探针用于直接在无细胞表达反应中表征蛋白酶 | Hejazi, S. | PDF | N/A | Single-Walled Carbon Nanotube Probes for Protease Characterization Directly in Cell-Free Expression Reactions | | RNA3DClust：基于聚类方法的RNA三维结构分割 | Le, Q. K. | PDF | N/A | RNA3DClust: segmentation of RNA three-dimensional structures using a clustering-based approach | | COSIME：协作式多视图集成与可扩展及可解释的模型解释器 | Choi, J. J. | PDF | N/A | COSIME: Cooperative multi-view integration and Scalable and Interpretable Model Explainer | | 梅尔基奥尔：一种混合型曼巴-Transformer RNA碱基识别器

非洲爪蟾中肾转录组学的比较分析：肾单位发育阶段的保守性

翻译说明： - "Comparative analysis" 译为“比较分析”。 - "Xenopus" 是非洲爪蟾的学名，译为“非洲爪蟾”。 - "mesonephric" 指的是中肾，译为“中肾”。 - "transcriptomics" 是转录组学的意思，译为“转录组学”。 - "Conservation" 在这里指进化上的保守性，译为“保守性”。 - "developmental lineage" 译为“发育谱系”。 - "nephron stages" 译为“肾单位阶段”。

不同冠层覆盖水平下山毛榉林在农林牧管理下的土壤碳固存

翻译说明： - Soil Carbon Sequestration：土壤碳固存，指土壤中碳的储存过程。 - Nothofagus obliqua：南美山毛榉，一种常见的南半球树种。 - Canopy Cover Levels：冠层覆盖水平，指森林中树冠的覆盖程度。 - Silvopastoral Management：农林牧管理，一种结合林业、农业和牧业的可持续土地利用方式。

希望这段翻译对你有帮助！ | Ramos, C. | PDF | N/A | Soil Carbon Sequestration in Nothofagus obliqua Forests with Different Canopy Cover Levels under Silvopastoral Management | | 在细胞动力学的最优传输中去偏Sinkhorn散度 | Cooper, J. | PDF | N/A | Debiasing Sinkhorn divergence in optimal transport of cellular dynamics | | 来自人类肿瘤的细胞对组织依赖性的机械感知 | Parihar, K. | PDF | N/A | Tissue-dependent mechanosensing by cells derived from human tumors | | 从果蝇到人类：CEBPZ、NOC2L和NOC3L在rRNA加工和肿瘤发生中的保守作用 | Rambaldelli, G. | PDF | N/A | From Flies to Humans: Conserved Roles of CEBPZ, NOC2L, and NOC3L in rRNA Processing and Tumorigenesis | | SYNGAP1酶活性和结构功能的分离：内在兴奋性和癫痫易感性 | Brill, J. | PDF | N/A | Dissociation of SYNGAP1 Enzymatic and Structural Roles: Intrinsic Excitability and Seizure Susceptibility | | 在小鼠肾脏发育过程中，亨利袢的细降支起源于近端小管细胞。 | Chung, E. | PDF | N/A | The thin descending limb of the loop of Henle originates from proximal tubule cells during mouse kidney development | | ECM签名揭示结肠生态位中静息干细胞的多样性 | Hickey, S. E. | PDF | N/A | ECM Signatures Reveal Quiescent Stem Cell Diversity in the Colonic Niche | | 奥比拉赫马特（乌兹别克斯坦）的箭头，距今约8万年前。 | Plisson, H. | PDF | N/A | Arrow heads at Obi-Rakhmat (Uzbekistan) 80 ka ago | | 视觉空间计算因类别和流线而异，并在青春期持续发展。 | Yao, J. K. | PDF | N/A | Visuospatial computations vary by category and stream and continue to develop in adolescence | | 亲和行为调节稳态的发展并塑造马匹的生物行为轨迹。 | Valenchon, M. | PDF | N/A | Affiliative behaviours regulate allostasis development and shape biobehavioural trajectories in horse | | 橄榄小脑系统差异性地编码感觉事件对行为的影响。 | Scheer, I. | PDF | N/A | The olivocerebellar system differentially encodes the effect sensory events exert on behavior | | 前额叶皮层微刺激对工作记忆的鲁棒性 | Soldado-Magraner, J. | PDF | N/A | Robustness of working memory to prefrontal cortex microstimulation | | 默认模式子网络和多需求区域对人物、地点和时间转换的专门化反应 | Zhou, A. X. | PDF | N/A | Specialized response of default mode subnetworks and multiple-demand regions to transitions of person, place and time | | 精神病大脑中的时空复杂性 | Li, Q. | PDF | N/A | Spatiotemporal Complexity in the Psychotic Brain | | 模拟小鼠初级运动皮层中的自组织和自持续群体活动模式 | Doherty, D. W. | PDF | N/A | Self-organized and self-sustained ensemble activity patterns in simulation of mouse primary motor cortex | | KAT6A乙酰化通过AMPK相互作用驱动代谢适应，从而介导细胞生长和线粒体代谢。 | Keller, M. A. | PDF | N/A | KAT6A acetylation drives metabolic adaptation to mediate cellular growth and mitochondrial metabolism through AMPK interaction | | HINT1的核质转位调节细胞密度的成熟 | Zhang, X. | PDF | N/A | The nucleocytoplasmic translocation of HINT1 regulates the maturation of cell density | | 鉴定两种在艰难梭菌（Clostridioides difficile）中合成膜糖脂所需的糖基转移酶 | Zbylicki, B. R. | PDF | N/A | Identification of two glycosyltransferases required for synthesis of membrane glycolipids in Clostridioides difficile | | 翻译：表征毒力调节因子Rns的配体结合口袋，Rns是AraC/XylS家族转录因子的成员。 | Tolbert, J. D. | PDF | N/A | Characterization of the ligand binding pocket of the virulence regulator Rns, a Member of the AraC/XylS family of transcription factors | | 大规模并行液滴共培养的元条形码分析 | Tan, J. Y. | PDF | N/A | Massively parallel metabarcoding of droplet co-cultures |

BioRxiv 2025-01-13 Papers

标题	作者	PDF链接	代码仓库	Title
DANGO：预测高阶遗传相互作用	Zhang, R.	PDF	N/A	DANGO: Predicting higher-order genetic interactions
在一片新型真菌疫情下，野生白蜡树种群中发生了快速的多基因适应性变化。	Metheringham, C. L.	PDF	N/A	Rapid polygenic adaptation in a wild population of ash trees under a novel fungal epidemic
从初始形成到发育完善：GABA能输入塑造初级体感皮层中的神经元亚网络	Huang, J.-Y.	PDF	N/A	From Initial Formation to Developmental Refinement: GABAergic Inputs Shape Neuronal Subnetworks in the Primary Somatosensory Cortex
海马皮层整合的两个长轴维度支持成年期记忆功能	Nordin, K.	PDF	N/A	Two long-axis dimensions of hippocampal cortical integration support memory function across the adult lifespan
阿尔茨海默病转分化神经元中的蛋白质稳态和溶酶体修复缺陷	Chou, C.-C.	PDF	N/A	Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease
指尖的记忆：粘弹性如何影响触觉神经元信号传递	Saal, H. P.	PDF	N/A	Memory at your fingertips: how viscoelasticity affects tactile neuron signaling
以下是将这段英文翻译成中文的结果：

皮质和皮质下全稳态-内感受系统在人脑中的映射：使用7特斯拉功能磁共振成像进行复制与扩展

翻译说明： 1. Cortical and subcortical mapping：皮质和皮质下映射，指的是对大脑皮层及其下结构的定位研究。 2. allostatic-interoceptive system：全稳态-内感受系统，涉及身体内部状态感知和调节的神经机制。 3. 7 Tesla fMRI：7特斯拉功能磁共振成像，是一种高分辨率的脑成像技术。

希望翻译对您有帮助！ | Zhang, J. | PDF | N/A | Cortical and subcortical mapping of the allostatic-interoceptive system in the human brain: replication and extension with 7 Tesla fMRI | | 慢性RNA G-四链体在衰老和阿尔茨海默病中的积累 | Kallweit, L. | PDF | N/A | Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer's Disease | | 一种新型遗传荧光报告基因用于可视化线粒体核小体 | Deng, J. | PDF | N/A | A novel genetic fluorescent reporter to visualize mitochondrial nucleoids | | 撤回：人类电压门控质子通道的构象动力学与配体结合 | Sun, X. | PDF | N/A | WITHDRAWN: Conformational Dynamics and Ligand Binding of the Human Voltage-Gated Proton Channel | | 在大脑-计算机接口任务期间，皮层树突中的向量化指导信号 | Francioni, V. | PDF | N/A | Vectorized instructive signals in cortical dendrites during a brain-computer interface task | | 全基因组关联研究与区域遗传力定位：瑞士大白猪的蛋白质效率和性能性状分析 | Ewaoluwagbemiga, E. O. | PDF | N/A | Genome-wide association study and regional heritability mapping of protein efficiency and performance traits in Swiss Large White pigs | | 语义和几何蛋白质编码以增强生物活性和热稳定性 | Tan, Y. | PDF | N/A | Semantical and Geometrical Protein Encoding Toward Enhanced Bioactivity and Thermostability | | 功能连接性、组织微结构和11.1特斯拉下的T2区分了大鼠两种创伤性脑损伤模型中的神经适应性差异：神经创伤转化结果项目（TOP-NT）UG3阶段研究 | Kommireddy, R. S. | PDF | N/A | Functional connectivity, tissue microstructure and T2 at 11.1 Tesla distinguishes neuroadaptive differences in two traumatic brain injury models in rats: A Translational Outcomes Project in NeuroTrauma (TOP-NT) UG3 phase study | | 通过一系列经过折叠调优的语言模型，蛋白质序列-结构图谱中未被探索的区域在大规模上得以揭示。 | Subramanian, A. M. | PDF | N/A | Unexplored regions of the protein sequence-structure map revealed at scale by a library of foldtuned language models | | Deleteome工具：利用酵母缺失株转录组数据集来识别共功能基因 | Neal, M. L. | PDF | N/A | DeleteomeTools: Utilizing a compendium of yeast deletion strain transcriptomes to identify co-functional genes | | 探索对比热带森林、树木组织及其发育阶段中的茜草科真菌内生菌 | Castillo-Gonzalez, H. | PDF | N/A | Exploring Rubiaceae fungal endophytes across contrasting tropical forests, tree tissues, and developmental stages | | 突变型GNAS在导管内乳头状黏液性肿瘤中驱动一种伴随肿瘤抑制性聚糖的幽门化生。 | Trinh, V. Q.-H. | PDF | N/A | Mutant GNAS drives a pyloric metaplasia with tumor suppressive glycans in intraductal papillary mucinous neoplasia | | 受体酪氨酸激酶CAD96CA和FGFR1作为昆虫保幼激素的细胞膜受体发挥作用。 | Li, Y.-X. | PDF | N/A | Receptor tyrosine kinases CAD96CA and FGFR1 function as the cell membrane receptors of insect juvenile hormone | | 基于精确度的因果推断调节视听时间再校准 | Li, L. | PDF | N/A | Precision-based causal inference modulates audiovisual temporal recalibration | | 通过Originator这一利用遗传和上下文信息的计算解密工具，拯救单细胞RNA测序数据中的血液污染问题。 | Unjitwattana, T. | PDF | N/A | Rescue Blood Contamination in scRNA-Seq Data by Originator, a Computational Deciphering Tool using Genetic and Contextual Information | | 单细胞RNA测序（scRNA-seq）和单细胞染色质可及性测序（scATAC-seq）揭示，在非梗阻性无精子症中，支持细胞通过阶段特异性通讯介导精子发生障碍。 | Wang, S. | PDF | N/A | ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia | | 共享通路特异性网络机制：多巴胺与深部脑刺激治疗帕金森病的共同作用 | Binns, T. S. | PDF | N/A | Shared pathway-specific network mechanisms of dopamine and deep brain stimulation for the treatment of Parkinson's disease | | 超越A和B区室：主要核定位如何定义核基因组组织和功能 | Gholamalamdari, O. | PDF | N/A | Beyond A and B Compartments: how major nuclear locales define nuclear genome organization and function | | 基于时空胃内容物数据量化两种底栖鱼类之间的食物竞争 | Lindmark, M. | PDF | N/A | Quantifying food competition between two demersal fish species from spatiotemporal stomach content data | | 从“一体化健康”视角看生态系统缺氧与抗菌素耐药基因的选择 | Ortiz-Miravalles, L. | PDF | N/A | Ecosystems Oxygen Deficiency and Selection of Antimicrobial Resistance Genes in a One Health Perspective | | Prosapip1在海马体背侧区域中调节突触蛋白组成、长时程增强效应以及空间记忆。 | Hoisington, Z. W. | PDF | N/A | Prosapip1 in the dorsal hippocampus mediates synaptic protein composition, long-term potentiation, and spatial memory | | 关于利用表型群体均值和等位基因频率数据进行全基因组关联研究（popGWAS）的潜力 | Pfenninger, M. | PDF | N/A | On the potential for GWAS with phenotypic population means and allele-frequency data (popGWAS) | | Linalool的多面抗菌潜力：揭示其对寄生水霉的抗菌效力及免疫调节作用 | Tao, T. | PDF | N/A | Linalool's Multifaceted Antimicrobial Potential: Unveiling its Antimicrobial Efficacy and Immunomodulatory Role Against Saprolegnia parasitica | | 移动整合子编码噬菌体防御系统 | Kieffer, N. | PDF | N/A | Mobile Integrons Encode Phage Defense Systems | | 表征阿尔茨海默病中Aβ寡聚体累积神经毒性的标准 | Kuznetsov, A. V. | PDF | N/A | A criterion characterizing accumulated neurotoxicity of Aβ oligomers in Alzheimer's disease | | 生物信息学家、计算机科学家和遗传学家共同领导生物信息学工具的开发——哪一个更好？ | Gardner, P. P. | PDF | N/A | A Bioinformatician, Computer Scientist, and Geneticist lead bioinformatic tool development - which one is better? | | Metapipeline-DNA：一个全面的种系与体细胞基因组学Nextflow流程

Metapipeline-DNA是一个基于Nextflow框架构建的综合性基因组学分析流程，旨在处理种系（germline）和体细胞（somatic）基因组数据。该流程整合了多种生物信息学工具和方法，能够高效地进行从原始测序数据到变异检测、注释及结果解读的全流程分析。无论是研究遗传性疾病、癌症基因组学，还是进行大规模群体基因组学研究，Metapipeline-DNA都提供了灵活且可扩展的解决方案，帮助研究人员快速、准确地解析基因组数据。 | Patel, Y. | PDF | N/A | Metapipeline-DNA: A Comprehensive Germline & Somatic Genomics Nextflow Pipeline | | 灵长类动物上丘中对暗对比度的微眼跳前敏感性增强更为显著 | Wu, W. | PDF | N/A | Stronger premicrosaccadic sensitivity enhancement for dark contrasts in the primate superior colliculus | | 对比反思室与虚拟现实头戴设备环境中呼吸练习与自然刺激的认知、行为和生理反应：随机对照研究 | Simonian, N. | PDF | N/A | Contrasting Cognitive, Behavioral, and Physiological Responses to Breathwork vs. Naturalistic Stimuli in Reflective Chamber and VR Headset Environments: Randomized Control Study | | 评估帕金森病中α-突触核蛋白寡聚体累积神经毒性的标准 | Kuznetsov, A. V. | PDF | N/A | Criterion for assessing accumulated neurotoxicity of alpha-synuclein oligomers in Parkinson's disease | | 梦境生成假说：基于回放依赖的可塑性机制模拟经典致幻剂的幻觉效应 | Bredenberg, C. | PDF | N/A | The oneirogen hypothesis: modeling the hallucinatory effects of classical psychedelics in terms of replay-dependent plasticity mechanisms | | 新型AI驱动的计算方法利用张量分解技术，用于在整合多个Hi-C数据集时识别共同的最优分箱大小。 | Taguchi, Y.-h. | PDF | N/A | Novel AI-powered computational method using tensor decomposition for identification of common optimal bin sizes when integrating multiple Hi-C datasets | | 以下是这段英文的中文翻译：

"来自犬类衰老项目（Dog Aging Project）的多样化犬群中，转座子的DNA甲基化模式揭示了衰老差异。"

翻译说明： - "DNA methylation of transposons" 翻译为 "转座子的DNA甲基化" - "pattern" 在这里是动词，意思是 "揭示...的模式" 或 "呈现...的模式" - "aging differences" 翻译为 "衰老差异" - "a diverse cohort of dogs" 翻译为 "多样化的犬群" - "from the Dog Aging Project" 翻译为 "来自犬类衰老项目"

希望这个翻译对你有帮助！ | Mariner, B. L. | PDF | N/A | DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project | | 在海马位置细胞序列中，脆性X综合征大鼠模型表现出受损。 | Donahue, M. M. | PDF | N/A | Hippocampal place cell sequences are impaired in a rat model of Fragile X Syndrome | | 研究大麦的甲基化组，其变异以及与基因组、转录组和表型变异的关联 | Kühl, M. A. | PDF | N/A | Investigating the barley methylome, its variation and association with genomic, transcriptomic, and phenotypic variation | | 恢复与多发性硬化症相关的肠道吲哚代谢物失衡可促进髓鞘再生并抑制神经炎症 | Jank, L. | PDF | N/A | Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation | | 钙稳态反馈控制预测心房颤动的发生、重构和进展 | Moise, N. | PDF | N/A | Calcium homeostatic feedback control predicts atrial fibrillation initiation, remodeling, and progression | | 丛枝菌根真菌基因型与核组织作为驱动因素在宿主植物养分获取和稳定碳储存中的作用 | Ferguson, R. | PDF | N/A | Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon storage | | KaMLs用于预测蛋白质pKa值和电离状态：树模型是否足够？ | Shen, M. | PDF | N/A | KaMLs for Predicting Protein pKa Values and Ionization States: Are Trees All You Need? | | 内质网驻留的脂质翻转酶对于顶复门寄生虫分泌细胞器的生物发生和功能至关重要。 | Reddy, G. S. | PDF | N/A | An ER-resident lipid scramblase is crucial for biogenesis and function of apicomplexan parasite secretory organelles | | 进化拯救模型为将癌细胞群体推向灭绝的策略提供了信息 | Dabi, A. | PDF | N/A | Evolutionary rescue model informs strategies for driving cancer cell populations to extinction | | 宫颈阴道微生物特征可预测沙眼衣原体在感染女性中向上生殖道的传播 | Jeong, S. | PDF | N/A | Cervicovaginal microbial features predict Chlamydia trachomatis spread to the upper genital tract of infected women | | 对涡虫再生特异性的比较分析揭示了轴向cWnt信号梯度对组织极性的贡献。 | Cleland, J. P. | PDF | N/A | A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient. | | mTOR信号通路通过S6K1-RhoA和aPKC-Lgl2轴调控上皮细胞顶端突起的形成。 | Sen, S. | PDF | N/A | mTOR signaling governs the formation of epithelial apical projection via S6K1-RhoA and aPKC-Lgl2 axes | | 控制血脑屏障和有孔毛细血管分离的血管生成机制源自多能脑血管微环境 | Lee, N. J. | PDF | N/A | Angiogenic mechanisms governing the segregation of blood-brain barrier and fenestrated capillaries derived from a multipotent cerebrovascular niche | | 撤回：细胞穿透肽在定鞭藻物种中的转运 | Gorrie, D. M. | PDF | N/A | WITHDRAWN: Cell-Penetrating Peptide Translocation in Haptophyte Species | | 在细菌泛基因组中使用CLARC进行基于连锁的同源基因优化 | Ojeda, I. G. | PDF | N/A | Linkage-based ortholog refinement in bacterial pangenomes with CLARC | | TEAD在神经祖细胞谱系进展过程中切换相互作用的伙伴，以执行不同的功能。 | Perry, C. H. | PDF | N/A | TEAD switches interacting partners along neural progenitor lineage progression to execute distinct functions | | 健身转位：通过基于生物学的数据增强改进变异效应预测 | Mialland, A. | PDF | N/A | Fitness translocation: improving variant effect prediction with biologically-grounded data augmentation | | 植物学可视化平台：一个全面的基于网络的工具，用于整合、可视化和分析植物及相关物种的组学数据 | Santiago, A. | PDF | N/A | The Plantae Visualization Platform: a comprehensive web-based tool for the integration, visualization, and analysis of omic data across plant and related species | | 使用MetHMMDb快速准确地检测金属抗性基因 | Ciuchcinski, K. | PDF | N/A | Fast and accurate detection of metal resistance genes using MetHMMDb | | Tapetum特异性TA29启动子受顺式元件调控，这些顺式元件结合了正调控因子和负调控因子。 | Sharma, P. A. | PDF | N/A | Tapetum specific TA29 promoter is regulated by cis- elements binding to positive and negative regulators | | 大型丝氨酸整合酶方向性控制的结构基础 | Shin, H. | PDF | N/A | Structural basis of directionality control in large serine integrases | | 钙触发的质外体ROS爆发平衡重力和机械信号以导航土壤 | Kulich, I. | PDF | N/A | Calcium-triggered apoplastic ROS bursts balance gravity and mechanical signals to navigate soil | | Chd4通过重塑染色质来控制视网膜细胞类型的特化和谱系终止 | Shah, S. | PDF | N/A | Chd4 remodels chromatin to control retinal cell type specification and lineage termination | | 性染色体和染色体重排是导致Jaera albifrons海洋等足类动物行为性隔离的关键因素。 | Ribardiere, A. | PDF | N/A | Sex chromosomes and chromosomal rearrangements are key to behavioural sexual isolation in Jaera albifrons marine isopods | | 建立临床前慢性伤口模型以表征蛇咬伤中毒的病理生理学 | Dawson, C. A. | PDF | N/A | Establishing a preclinical chronic wound model to characterise the pathophysiology of snakebite envenoming | | 系统性红斑狼疮中抗核抗原（ANA）反应性B细胞的选择。 | Atisha-Fregoso, Y. | PDF | N/A | SELECTION OF ANTI-NUCLEAR ANTIGEN (ANA) REACTIVE B CELLS IN SYSTEMIC LUPUS ERYTHEMATOSUS. | | Escobase 和 AcR：来自牛场分离株的大肠杆菌基因组和耐酸基因数据库 | Martin, L. | PDF | N/A | Escobase and AcR: Escherichia coli databases of genomes and acid resistance genes from isolates from cattle farms | | CRISPR/Cas9介导的社会性寄生蜂Sclerodermus guani的生殖系突变 | Ye, Z. | PDF | N/A | CRISPR/Cas9-mediated germline mutagenesis in the subsocial parasitoid wasp, Sclerodermus guani | | 由驱动蛋白3（Kinesin 3）运输的线粒体通过阻止局部钙离子尖峰来抑制依赖半胱天冬酶（caspase）的特异性细胞死亡。 | Sharmin, R. | PDF | N/A | Mitochondria transported by Kinesin 3 prevent localized calcium spiking to inhibit caspase-dependent specialized cell death | | 一个与疾病相关的GluN2B变异体通过自噬促进NMDA受体的降解。 | Benske, T. M. | PDF | N/A | A GluN2B disease-associated variant promotes degradation of NMDA receptors via autophagy | | 成纤维细胞收缩性驱动肠道息肉病中的网络重组和上皮细胞增殖 | Li, M.-L. | PDF | N/A | Fibroblast contractility drives network reorganization and epithelial proliferation in intestinal polyposis | | 跨气候梯度的粮食安全作物中的病原体和害虫群落：预见非洲大湖地区未来的挑战 | Mouafo-Tchinda, R. | PDF | N/A | Pathogen and pest communities in food security crops across climate gradients: Anticipating future challenges in the Great Lakes region of Africa | | 基于可解释机器学习和振荡法的诊断支持系统，用于准确诊断矽肺病中的呼吸功能障碍 | Melo, P. L. d. | PDF | N/A | A diagnostic support system based on interpretable machine learning and oscillometry for accurate diagnosis of respiratory dysfunction in silicosis | | 以下是这段文字的中文翻译：

截断BK通道电压激活的原子模拟

翻译说明： - "Atomistic Simulation" 翻译为 "原子模拟"，指的是在原子级别进行的模拟。 - "Voltage Activation" 翻译为 "电压激活"，指的是通过电压变化激活某种机制。 - "Truncated BK Channel" 翻译为 "截断BK通道"，指的是经过截断处理的BK通道（一种离子通道）。

希望这个翻译对你有帮助！如果需要进一步调整或解释，请告诉我。 | Jia, Z. | PDF | N/A | Atomistic Simulation of Voltage Activation of a Truncated BK Channel | | 来自巴西东部居维叶洞穴的大型犰狳科（Dasypodidae Gray, 1821）的存在 | Chahud, A. | PDF | N/A | PRESENCE OF A LARGE DASYPODIDAE GRAY, 1821 FROM THE CUVIERI CAVE, EASTERN BRAZIL | | 单核转录组学揭示了杨树中生长素驱动的木材可塑性和强耐旱性机制 | Gomez-Soto, D. | PDF | N/A | Single-nuclei transcriptomics revealed auxin-driven mechanisms of wood plasticity and severe drought tolerance in poplar | | 重要提示：通过扫描电子显微镜（SEM）和计算机视觉技术对印度药用植物进行高级花粉分类 | Khalane, J. S. | PDF | N/A | IMPORTANT: Advanced Pollen Classification of Indian Medicinal Plants through SEM and Computer Vision | | 胡萝卜中的内源性法卡林醇型聚乙炔及其对采后真菌病原菌 Mycocentrospora acerina 和 Botrytis cinerea 的潜在影响 | He, W. | PDF | N/A | Endogenous falcarinol-type polyacetylenes in carrots and their putative influence on post-harvest fungal pathogens Mycocentrospora acerina and Botrytis cinerea | | 《幼年地中海贻贝（Mytilus galloprovincialis）的冷冻保存：保护软体动物生物多样性与水产养殖》

此标题翻译为中文，意为通过冷冻保存技术对幼年地中海贻贝进行保护，旨在维护软体动物的生物多样性，并促进水产养殖业的可持续发展。 | Paredes, E. | PDF | N/A | Cryopreservation of Juvenile Mytilus galloprovincialis: Safeguarding Mollusk Biodiversity and Aquaculture | | α-微管蛋白中的Treg细胞表位：发现与免疫调节特性 | Fiyouzi, T. | PDF | N/A | Treg cell epitopes from α-tubulin: discovery and immunomodulatory features | | 在缺乏环挤压的情况下，顺式调控染色质接触会重新形成。 | Aboreden, N. | PDF | N/A | Cis-regulatory chromatin contacts form de novo in the absence of loop extrusion | | SQST-1/p62调控的SKN-1/Nrf通过转录激活lyst-1/LYST介导吞噬应激反应。 | Elkhalil, A. | PDF | N/A | SQST-1/p62-regulated SKN-1/Nrf mediates a phagocytic stress response via transcriptional activation of lyst-1/LYST | | 高尔基体相关核输入受体importin-7将HPV从高尔基体转运至细胞核，以促进感染。 | Woo, T.-T. | PDF | N/A | Golgi-associated nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection | | 肽类色氨酸卤化通过一种多功能黄素依赖酶进行 | Rice, A. | PDF | N/A | Peptidic tryptophan halogenation by a promiscuous flavin-dependent enzyme | | 一个密封的样品室使得在体外对病原微生物进行延时纳米级表征成为可能。 | Braun, E. | PDF | N/A | A hermetically closed sample chamber enables time-lapse nano-characterization of pathogenic microorganisms in-vitro | | PPIFold：一种用于分析AlphaPullDown中蛋白质-蛋白质相互作用的工具 | Rouger, Q. | PDF | N/A | PPIFold: A Tool for Analysis of Protein-Protein Interaction from AlphaPullDown | | 磷酸化模式调节RNA聚合酶II CTD的瞬时二级结构，而不改变其整体构象。 | Chen, W. | PDF | N/A | Phosphorylation patterns modulate the transient secondary structure of RNA polymerase II CTD without altering its global conformation | | 在转录组水平解读肺癌健康差异 | Sobhan, M. | PDF | N/A | Interpreting Lung Cancer Health Disparity at Transcriptome Level | | AUTO-SP：用于分析蛋白质及蛋白质修饰的自动化样品制备 | Lih, T. M. | PDF | N/A | AUTO-SP: automated sample preparation for analyzing proteins and protein modifications | | 蒙特卡洛模拟预测，高智商和低智商的个体在真实脑电图（EEG）模式上存在显著差异。 | Tozzi, A. | PDF | N/A | Monte Carlo simulations predict distinct real EEG patterns in individuals with high and low IQs | | C反应蛋白与镰状细胞病女性的月经周期 | Wu, J. | PDF | N/A | C-reactive protein and the menstrual cycle in females with sickle cell disease | | 组蛋白H4赖氨酸20的单甲基化不是转录沉默子的标志。 | Segert, J. A. | PDF | N/A | Histone H4 lysine 20 monomethylation is not a mark of transcriptional silencers | | 是否存在一种病理性的开关，能够触发肾钙化的开始？ | Jeewandara, T. M. | PDF | N/A | Is there a pathological switch that triggers the onset of renal calcification? | | 在生物反应器中，机械刺激后，Piezo1的激活增加了治疗性细胞外囊泡的释放。 | Andrade, A. C. | PDF | N/A | Piezo1 activation increases the release of therapeutic extracellular vesicles after mechanical stimulation in bioreactors | | RNA加工的改变为解析与RNA解旋酶DHX37致病性变异相关的人类性别逆转提供了机制框架。 | Elzaiat, M. | PDF | N/A | Altered RNA-processing provides a mechanistic framework delineating human sex reversal associated with pathogenic variants in the RNA-helicase DHX37 | | 鉴定了一种新的上皮细胞中需要BMP结合的GREMLIN1摄取途径 | Brazil, D. | PDF | N/A | Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding | | 在斑马鱼幼体中，光感受器外节吞噬作用的节律性在锥细胞亚型之间存在差异。 | Partinen, J. | PDF | N/A | Rhythmicity of photoreceptor outer segment phagocytosis differs between the cone subtypes in the larval zebrafish | | PSME3 调控成肌细胞的迁移和分化 | Kuhn, K. D. | PDF | N/A | PSME3 Regulates Migration and Differentiation of Myoblasts | | 质膜介导的GLUT10线粒体靶向调节细胞内抗坏血酸稳态 | Jose, A. C. | PDF | N/A | Plasma membrane mediated GLUT10 mitochondrial targeting regulates intracellular ascorbic acid homeostasis | | ZO-1/ZO-2缺陷细胞的竞争性消除调节上皮屏障稳态 | Otani, T. | PDF | N/A | Competitive elimination of ZO-1/ZO-2-deficient cells regulates epithelial barrier homeostasis | | 界面张力和生长两者共同影响机械细胞竞争。 | Valon, L. | PDF | N/A | Interfacial tension and growth both contribute to mechanical cell competition | | 外泌体miR-145-5p通过JNK信号通路促进肾小管上皮细胞凋亡 | Deng, X. | PDF | N/A | Exosomal miR-145-5p promotes apoptosis of renal tubule epithelial cells through the JNK signalling pathway | | 一种基于公民科学的新型野生动物监测和管理工具，适用于油棕种植园 | Maharani, N. | PDF | N/A | A novel citizen science-based wildlife monitoring and management tool for oil palm plantations | | 机器学习识别出常规血液检测可作为预测污染相关认知功能下降的准确指标。 | Johnson, H. | PDF | N/A | Machine learning identifies routine blood tests as accurate predictive measures of pollution-dependent poor cognitive function | | 犬尿氨酸代谢与选择性5-羟色胺再摄取抑制剂的抗抑郁反应相关 | RAMPERSAUD, R. | PDF | N/A | Kynurenine Metabolism is Associated with Antidepressant Response to Selective Serotonin Reuptake Inhibitors | | 以下是这段文字的中文翻译：

与情绪相关的静息态网络在症状性双相I/II型障碍青少年中的纵向稳定性

利用FcRn介导的循环LYTACs催化降解循环靶标

翻译说明： - "Catalytic degradation" 翻译为 "催化降解" - "circulating targets" 翻译为 "循环靶标" - "FcRn-mediated cycling" 翻译为 "FcRn介导的循环" - "LYTACs" 是专有名词，通常指 "溶酶体靶向嵌合体"（Lysosome-Targeting Chimeras），在此保留英文缩写。

证据表明扁形动物中Fox基因家族经历了多次独立的扩张

翻译解释： - Evidence for：证据表明 - multiple independent expansions：多次独立的扩张 - Fox gene families：Fox基因家族 - within flatworms：在扁形动物中

研究表明，无法在脑海中形成图像的人对故事的情感反应较弱。

你是否曾经在阅读一本扣人心弦的小说时，感觉自己仿佛置身于故事之中，与角色同呼吸共命运？这种身临其境的体验很大程度上依赖于我们脑海中生动的想象画面。然而，对于患有心盲症（aphantasia）的人来说，这种体验却截然不同。他们无法在脑海中形成图像，因此对故事的情感投入也会受到影响。

心盲症与情感反应

一项最新研究发现，心盲症患者在阅读情感丰富的故事时，其生理和情感反应都较弱。研究人员通过测量参与者的皮肤电导率（一种衡量情绪唤醒的指标）发现，与能够正常想象的人相比，心盲症患者在阅读悲伤或恐惧的故事时，皮肤电导率的变化较小。此外，心盲症患者自我报告的情感体验也较弱。

想象力的力量

这项研究强调了想象力在情感体验中的重要作用。当我们阅读故事时，脑海中形成的图像能够帮助我们更好地理解和感受角色的情感，从而产生更强烈的情感共鸣。对于心盲症患者来说，由于缺乏这种视觉想象力，他们可能更难与故事中的角色产生情感连接。

超越视觉的想象力

然而，这并不意味着心盲症患者无法享受阅读的乐趣。他们可能会通过其他方式，例如关注语言的韵律、故事的节奏或角色的内心独白，来体验故事的情感深度。此外，一些心盲症患者可能会发展出更强的其他感官想象力，例如听觉或触觉，来弥补视觉想象力的缺失。

总结

这段翻译将原文的科技内容准确地转化为中文，保持了专业术语的准确性，如“30色纵向全光谱免疫表型分析及分选技术”和“系统性自身免疫性风湿病”，同时也确保了句子的流畅性和专业性。 | Jiwrajka, N. | PDF | N/A | 30-Color Longitudinal Full-Spectrum Immunophenotyping and Sorting of Human Circulating Immune Cell Subsets Implicated in Systemic Autoimmune Rheumatic Diseases | | 环北方区异源多倍体食虫植物长叶茅膏菜（茅膏菜科）亚基因组的起源 | Mohn, R. | PDF | N/A | Origin of subgenomes in the circumboreal allopolyploid carnivorous plant Drosera anglica (Droseraceae) | | 与基于估计育种值的选择相比，改进选择的策略 | Pook, T. | PDF | N/A | Strategies to improve selection compared to selection based on estimated breeding values | | 减少膳食蛋白质摄入会导致牙科蛋白质组发生变化 | Burroughs, R. W. | PDF | N/A | Reduced Dietary Protein Induces Changes in the Dental Proteome | | Kruppel样因子在调节多能性和神经嵴干细胞形成中发挥重要作用 | Rigney, S. | PDF | N/A | Kruppel-like Factors Play Essential Roles in Regulating Pluripotency and the Formation of Neural Crest Stem Cells | | Ptpn14基因敲除小鼠揭示了Hippo通路在雌性中的关键作用 | McCrea, E. M. | PDF | N/A | Ptpn14 Knockout Mice Reveal Critical Female-Specific Roles for the Hippo Pathway | | 分形支气管树的出现 | Mederacke, M. | PDF | N/A | The emergence of the fractal bronchial tree | | 持续熟悉度解码来自脉冲网络中的循环连接 | Zemliak, V. | PDF | N/A | Continual familiarity decoding from recurrent connections in spiking networks | | 前顶叶活动与工作记忆的神经心理学评估相关 | Jurva, A. | PDF | N/A | Frontoparietal activity related to neuropsychological assessment of working memory | | 神经元类型特异的mRNA翻译程序为记忆巩固提供了途径。 | Oliveira, M. M. | PDF | N/A | Neuron type-specific mRNA translation programs provide a gateway for memory consolidation. | | 视听伽马刺激增强老年小鼠海马神经发生和神经回路可塑性 | Trinchero, M. | PDF | N/A | Audiovisual gamma stimulation enhances hippocampal neurogenesis and neural circuit plasticity in aging mice | | 细胞突介导的信号传导协调了果蝇眼中胶质细胞和神经元的发育。 | Garcia-Arias, J. M. | PDF | N/A | Cytoneme-mediated signalling coordinates the development of glial cells and neurons in the Drosophila eye | | 果蝇发育中类二十烷酸信号的功能表征 | Fujinaga, D. | PDF | N/A | Functional characterization of eicosanoid signaling in Drosophila development | | MiRNA-501-3p 和 MiRNA-502-3p：阿尔茨海默病的有前景的生物标志物组合 | Devara, D. | PDF | N/A | MiRNA-501-3p and MiRNA-502-3p: A Promising Biomarker Panel for Alzheimer's Disease | | MicroRNA-502-3p调节海马神经元中的GABA A亚基、突触蛋白和线粒体形态。 | Sharma, B. | PDF | N/A | MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons | | 构建基于生物学约束的递归神经网络：通过Dale的反向传播和拓扑信息剪枝方法 | Balwani, A. | PDF | N/A | Constructing Biologically Constrained RNNs via Dale's Backprop and Topologically-Informed Pruning | | 闭眼静息状态下的脑电图（EEG）比睁眼静息状态下的脑电图更能清晰且稳定地揭示自闭症个体与神经典型个体之间的群体差异。 | Xiao, W. | PDF | N/A | Eyes-closed resting state EEG reveals clearer and more stable group differences between autistic and neurotypical individuals than eyes-open resting state EEG | | 葡萄糖脑苷脂酶缺乏导致人类星形胶质细胞脂质代谢失调 | Tahanis, A. | PDF | N/A | Glucocerebrosidase Deficiency Dysregulates Human Astrocyte Lipid Metabolism | | 依赖CO2的Connexin 43半通道开放 | Dospinsecu, V. M. | PDF | N/A | CO2-dependent opening of Connexin 43 hemichannels | | 外周酒精代谢决定小鼠的乙醇消耗和饮酒微观结构 | Mackowiak, B. | PDF | N/A | Peripheral alcohol metabolism dictates ethanol consumption and drinking microstructure in mice | | 星形胶质细胞和线粒体在脑源性细胞外囊泡中的足迹可预测tau蛋白病理 | Espourteille, J. | PDF | N/A | Astrocyte and mitochondrial footprints in brain-derived extracellular vesicles predict tau pathology | | 工作记忆主动清除的脑电图相关研究 | Shan, J. | PDF | N/A | EEG correlates of active removal from working memory | | 不可靠突触平衡网络中的噪声相关性 | Leone, M. J. | PDF | N/A | Noise Correlations in Balanced Networks with Unreliable Synapses | | 人类腹侧通路中与动态面部相关的眼动表征 | Su, Z. | PDF | N/A | Dynamic face-related eye movement representations in the human ventral pathway | | 以下是将这段英文翻译成中文的结果：

表征基底外侧杏仁核中的少突胶质细胞系细胞和髓鞘形成：来自人类死后大脑新方法的见解

翻译说明： 1. "Characterizing" 翻译为“表征”，表示对某事物的特性进行描述或分析。 2. "Oligodendrocyte-Lineage Cells" 翻译为“少突胶质细胞系细胞”，指的是少突胶质细胞及其前体细胞。 3. "Myelination" 翻译为“髓鞘形成”，指的是神经纤维周围髓鞘的生成过程。 4. "Basolateral Amygdala" 翻译为“基底外侧杏仁核”，是大脑杏仁核的一部分。 5. "Insights from a Novel Methodology" 翻译为“来自新方法的见解”，表示通过一种新的研究方法获得的发现。 6. "Postmortem Human Brain" 翻译为“人类死后大脑”，指的是对去世后的人脑进行研究。

《Eurydice pulchra 和 Parhyale hawaiensis 脑中时钟基因表达的昼夜节律和潮汐节律振荡》

翻译说明： - Circadian：昼夜节律，指生物体以大约24小时为周期的生理和行为变化。 - Circatidal：潮汐节律，指生物体与潮汐周期（约12.4小时）相关的生理和行为变化。 - Clock gene expression：时钟基因表达，指与生物钟相关的基因的转录和翻译过程。 - Eurydice pulchra 和 Parhyale hawaiensis：两种海洋甲壳类动物的学名，分别是美丽海蟑螂和夏威夷片脚类动物。

希望翻译对你有帮助！ | Oliphant, A. | PDF | N/A | Circadian and circatidal oscillations of clock gene expression in brains of Eurydice pulchra and Parhyale hawaiensis. | | 对情感强烈的小鼠发声的声学特征和行为反应的研究 | Ghasemahmad, Z. | PDF | N/A | Acoustic features of and behavioral responses to emotionally intense mouse vocalizations | | 小鼠上丘中对自然声音响应的听觉神经元的特性研究 | Si, Y. | PDF | N/A | Characterization of auditory responsive neurons in the mouse superior colliculus to naturalistic sounds | | 选择性靶向致病性Tau种子的新型VHH方法 | GUPTA, A. | PDF | N/A | Selective Targeting of Pathogenic Tau Seeds via a Novel VHH | | 标题：TRIM72对ALS疾病进展的细胞自主和非细胞自主影响 | Jia, Y. | PDF | N/A | Title: Cell-autonomous and non-cell-autonomous effects of TRIM72 on ALS disease progression | | dlmoR: 一个用于暗光褪黑激素起始（DLMO）曲棍球棒方法的开源R包 | Thalji, S. M. | PDF | N/A | dlmoR: An open-source R package for the dim-light melatonin onset (DLMO) hockey-stick method | | 脑源性神经营养因子（BDNF）在腹外侧眶额叶皮层到背外侧纹状体回路中调节酒精消耗并控制酒精习惯的形成。 | Gunasekaran, S. | PDF | N/A | BDNF in Ventrolateral Orbitofrontal Cortex to Dorsolateral Striatum Circuit Moderates Alcohol Consumption and Gates Alcohol Habit | | 平滑追踪眼动有助于下肢的长潜伏期反射调节。 | Sinha, O. | PDF | N/A | Smooth pursuit eye movements contribute to long-latency reflex modulation in the lower extremity | | 人体海马体内白质通路的活体定量研究 | Gumus, M. | PDF | N/A | In vivo Quantification of White Matter Pathways in the Human Hippocampus | | 杏仁核回路中巴甫洛夫式学习和工具性学习的共同神经基础 | Riffault, C. | PDF | N/A | A common neuronal basis for Pavlovian and instrumental learning in amygdala circuits | | 脯氨酰异构酶FKBP12通过抑制CRMP2A减少轴突生长并负调控微管聚合。 | Weissova, R. | PDF | N/A | Prolyl isomerase FKBP12 reduces axon growth and negatively regulates microtubule polymerization by inhibiting CRMP2A | | 自监督深度学习模型能更好地模拟人类高级视觉皮层：多模态与训练数据集规模的作用 | Grosbard, I. D. | PDF | N/A | Self-supervision deep learning models are better models of human high-level visual cortex: The roles of multi-modality and dataset training size | | EEG-informed fMRI分析揭示了运动执行和运动想象中的神经血管耦合 | Bondi, E. | PDF | N/A | EEG-Informed fMRI Analysis Reveals Neurovascular Coupling in Motor Execution and Imagery | | 脊髓超声刺激调节皮质脊髓兴奋性 | Hou, L. | PDF | N/A | Spinal Cord Ultrasound Stimulation Modulates Corticospinal Excitability | | 生境转变对安第斯异质景观中两栖动物和爬行动物群落的影响 | Falcon-Espitia, N. | PDF | N/A | Impacts of Habitat Transformation on Amphibian and Reptile Communities in a Heterogeneous Andean Landscape | | 破碎化景观的承载能力取决于物种的家域大小。 | Pereira, H. M. | PDF | N/A | The carrying capacity of a fragmented landscape depends on the home-range size of a species | | 系统发育生物群落生态位保守性是热带非洲古特有豆科森林树种进化的基础 | Ojeda Alayon, D. | PDF | N/A | Phylogenetic biome niche conservatism underlies the evolution of forest paleoendemic legume trees in tropical Africa | | 祖先和近期的转座子爆发塑造了植物病原锈菌的巨大基因组。 | Corre, E. | PDF | N/A | Ancestral and recent bursts of transposition shaped the massive genomes of plant pathogenic rust fungi | | 翻转环流塑造了南太平洋的微生物功能景观 | Kolody, B. C. | PDF | N/A | Overturning circulation structures the microbial functional landscape of the South Pacific | | 以下是这段文字的中文翻译：

来自印度北部的六株临床分离的嗜麦芽窄食单胞菌的基因组洞察

这段文字提到了对来自印度北部的六株临床分离的嗜麦芽窄食单胞菌（Stenotrophomonas maltophilia）的基因组研究。 | Gheewalla, N. | PDF | N/A | Genomic insights into six clinical isolates of Stenotrophomonas maltophilia from Northern India | | 一种由饥饿触发的AAA+ ATP酶通过分解细菌DNA滑动夹来停止染色体复制进程。 | Surbhi, S. | PDF | N/A | A starvation-triggered AAA+ ATPase halts chromosome replication progression by disassembling the bacterial DNA sliding clamp | | ATG-3通过调控胶原蛋白途径限制Orsay病毒在秀丽隐杆线虫（C. elegans）中的感染。 | Kalugotla, G. | PDF | N/A | ATG-3 limits Orsay virus infection in C. elegans through regulation of collagen pathways | | 实验性弓形虫病在空间上的代谢影响差异：免疫学和微生物学的相关性 | Lesani, M. | PDF | N/A | Spatially-divergent metabolic impact of experimental toxoplasmosis: immunological and microbial correlates | | 通过数据依赖性和数据独立性采集质谱法对铜绿假单胞菌中锌稳态机制的蛋白质组学分析 | Meyer, A. C. | PDF | N/A | Proteomic profiling of zinc homeostasis mechanisms in Pseudomonas aeruginosa through data-dependent and data-independent acquisition mass spectrometry | | 揭示基于基础模型框架的肠道微生物中抗菌肽的进化 | LI, W. | PDF | N/A | Unveiling the Evolution of Antimicrobial Peptides in Gut Microbes via Foundation Model-Powered Framework | | 分析鲍曼不动杆菌中非碳青霉烯酶介导的碳青霉烯类抗生素耐药性的潜在机制 | Hoefken, L.-M. | PDF | N/A | Analysis of potential mechanisms of non-carbapenemase mediated carbapenem resistance in Acinetobacter baumannii | | 氯霉素诱导的枯草芽孢杆菌提高了多种抗生素抗性基因的瞬时表达，包括糖肽类抗生素腐草霉素和博莱霉素。 | LaBonte, S. A. | PDF | N/A | Chloramphenicol-mobilized Bacillus subtilis elevates transient expression of multiple antibiotic resistance genes, including the glycopeptides phleomycin and bleomycin | | 常用的非抗生素药物会增加大肠杆菌的突变频率和抗菌素耐药性。 | Chen, H. | PDF | N/A | Commonly used non-antibiotic medications promote mutation frequency and antimicrobial resistance in Escherichia coli | | 利用数字液滴PCR技术检测致病疫霉（Phytophthora infestans）对羧酸酰胺类（CAA）杀菌剂的抗性。 | Kaur, A. | PDF | N/A | Detection of resistance in Phytophthora infestans to the carboxylic acid amide (CAA) fungicides using digital droplet PCR. | | 全球原核生物中温度和营养限制的DNA特征 | Antman, T. | PDF | N/A | Global DNA signatures of temperature and nutrient limitation in prokaryotes | | ATR，一种DNA损伤激酶，调节大利什曼原虫的DNA复制时序。 | Almeida Da Silva, G. L. | PDF | N/A | ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major. | | α-突触核蛋白聚集体通过隔离和附带降解抑制ESCRT-III | Sitron, C. S. | PDF | N/A | Alpha-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation |

BioRxiv 2025-01-12 Papers

标题	作者	PDF链接	代码仓库	Title
无监督无参考推断揭示了人类单细胞中未被识别的受调控转录组复杂性。	Dehghannasiri, R.	PDF	N/A	Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells
自动多感官整合遵循主观信心而非客观表现	Gao, Y.	PDF	N/A	Automatic multisensory integration follows subjective confidence rather than objectiveperformance
原核代谢体的结构架构揭示了介导多种蛋白质-蛋白质相互作用的保守界面	Bhattacharyya, S.	PDF	N/A	Structural architecture of a prokaryotic metabolon reveals conserved interfaces mediating multiple protein-protein interactions
饮食蛋白质来源改变肠道微生物群的组成和功能	Blakeley-Ruiz, J. A.	PDF	N/A	Dietary protein source alters gut microbiota composition and function
皮层对层次节奏的跟踪协调了生物运动的多感官处理	Shen, L.	PDF	N/A	Cortical tracking of hierarchical rhythms orchestrates the multisensory processing of biological motion
APOE3-R136S突变通过抑制cGAS-STING-IFN通路，赋予了对tau病理的抵抗力。	Naguib, S. A.	PDF	N/A	APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition
核内Argonaute蛋白NRDE-3在胚胎发育过程中切换小RNA伙伴，以介导时间特异性的基因调控活性。	Chen, S.	PDF	N/A	Nuclear Argonaute protein NRDE-3 switches small RNA partners during embryogenesis to mediate temporal-specific gene regulatory activity
脂质膜对RNA催化活性和稳定性的影响	Czerniak, T.	PDF	N/A	Effects of lipid membranes on RNA catalytic activity and stability
量化野猪互动以构建疾病传播网络	Proboste, T.	PDF	N/A	Quantifying Feral Pig Interactions to Inform Disease Transmission Networks
TWINKLE：一款用于教学和研究的开源双光子显微镜	Schottdorf, M.	PDF	N/A	TWINKLE: An open-source two-photon microscope for teaching and research
小脑性伸手共济失调对运动学和动力学需求的敏感性	Oh, K.	PDF	N/A	Sensitivity of Cerebellar Reaching Ataxia to Kinematic and Dynamic Demands
DNA复制叉速度在皮层神经发生中充当引擎	Wang, J.	PDF	N/A	DNA replication fork speed Acts as an Engine in Cortical Neurogenesis
一种新型的RyR2选择性稳定剂可在不影响心脏功能的情况下预防应激诱导的室性心动过速	Kurebayashi, N.	PDF	N/A	A novel RyR2-selective stabilizer prevents stress-induced ventricular tachycardia without compromising cardiac function
Vγ1+ γδ T细胞来源的IL-4启动CD8 T细胞免疫	Le, S.	PDF	N/A	Vgamma1+ gammadelta T cell-derived IL-4 initiates CD8 T cell immunity
食品来源的化合物延长冷冻人乳的保质期	Silpe, J. E.	PDF	N/A	Food-Derived Compounds Extend the Shelf-Life of Frozen Human Milk
一种用于预测蛋白质内在无序区域相互作用的深度学习方法	Majila, K.	PDF	N/A	A deep learning method for predicting interactions for intrinsically disordered regions of proteins
Nurr1调控屏状核的发育与功能	Yan, K.	PDF	N/A	Nurr1 orchestrates claustrum development and functionality
动态转录组重塑揭示人类神经祖细胞在视网膜色素变性模型中保护视力的机制	Shahin, S.	PDF	N/A	Dynamic Transcriptomic Remodeling in Human Neural Progenitor Cells Reveals Mechanisms for Vision Preservation in Retinitis Pigmentosa Model
阻塞性睡眠呼吸暂停中的脂肪细胞醛固酮	Dong, Y.	PDF	N/A	Adipocyte Aldosterone in Obstructive Sleep Apnea
Tke5是一种新型的恶臭假单胞菌毒素，它能够使膜去极化，从而杀死植物病原体。	Velazquez, C.	PDF	N/A	Tke5 is a novel Pseudomonas putida toxin that depolarises membranes killing plant pathogens
将bovicin HC5和ε-聚赖氨酸对橙汁中耐酸热芽孢杆菌（Alicyclobacillus acidoterrestris）的联合效应翻译成中文为：bovicin HC5和ε-聚赖氨酸对橙汁中耐酸热芽孢杆菌的联合效应。	Iduu, N. V.	PDF	N/A	Combinatorial effects of bovicin HC5 and epsilon-polylysine against Alicyclobacillus acidoterrestris in orange juice
使用牛津纳米孔技术（ONT）进行超短DNA测序的高性能协议	Zemaitis, L.	PDF	N/A	High Performance protocol for ultra-short DNA sequencing using Oxford Nanopore Technology (ONT)
SAPID：一种深入分析植物提取物味道的策略。应用于Swertia chirayita (Roxb.) H.Karst.的复杂味道。	Rutz, A.	PDF	N/A	SAPID: a Strategy to Analyze Plant Extracts Taste In Depth. Application to the complex tasteof Swertia chirayita (Roxb.) H.Karst.
以下是这段文字的中文翻译：

从低成本生态计数数据中检测种群趋势的变化 | Singer, L. | PDF | N/A | Testing for changes in population trends from low-cost ecological count data | | 拟南芥基因组-环境关联的实验验证 | Luo, Y. | PDF | N/A | Experimental validation of genome-environment associations in Arabidopsis | | 多变量孟德尔随机化调整遗传混杂因素，分析C反应蛋白对多种疾病的因果影响。 | Shi, R. | PDF | N/A | Multivariable Mendelian Randomization adjusting for heritable confounding analyzes the causal effects of C-reactive protein on multiple diseases | | 昆虫病原性线虫Steinernema hermaphroditum及其共生细菌的基因组 | Schwarz, E. M. | PDF | N/A | Genomes of the entomopathogenic nematode Steinernema hermaphroditum and its associated bacteria | | 通过随机诱变方法提高锌金属蛋白酶的酶效率：突变体酶学及结构特性的研究 | Srivastava, N. | PDF | N/A | Improvement in the enzymatic efficiency of a zinc metalloprotease through random mutagenesis approach: Studies on the enzymatic and structural properties of the mutant | | 胆汁酸敏感离子通道通过跨膜结构域中依赖Ca2+的构象变化来开启。 | Freitas, M. M. | PDF | N/A | The bile acid-sensitive ion channel is gated by Ca2+-dependent conformational changes in the transmembrane domain | | 胶原水凝胶管微生物反应器用于细胞和组织制造 | Yang, Y. | PDF | N/A | Collagen Hydrogel Tube Microbioreactors for Cell and Tissue Manufacturing | | 基于动态规范的灵长类听觉皮层中声音身份的编码 | Esposito, Y. | PDF | N/A | Dynamic Norm-Based Coding of Vocal Identity in the Primate Auditory Cortex | | Drosophila littoralis 昼夜节律与光周期纬度梯度之间的相关性 | Manoli, G. | PDF | N/A | Correlation between circadian and photoperiodic latitudinal clines in Drosophila littoralis | | pH调节提高了抑制性柳枝稷水解产物中的生物燃料产量 | Barten, L. M. | PDF | N/A | pH adjustment increases biofuel production from inhibitory switchgrass hydrolysates | | 厌氧甲烷氧化过程中关键酶MCR的原子分辨率结构揭示了新颖且广泛的翻译后修饰。 | Müller, M.-C. | PDF | N/A | Atomic resolution structures of key enzyme MCR in anaerobic methanotrophy reveal novel and extensive post-translational modifications. | | 逆转录病毒Gag凝聚体与转录爆发位点新生病毒RNA的动态相互作用：对基因组RNA包装的影响 | Kaddis Maldonado, R. J. | PDF | N/A | Dynamic interactions of retroviral Gag condensates with nascent viral RNA at transcriptional burst sites: implications for genomic RNA packaging | | 肠道微生物组中的表观遗传相位变异增强了细菌的适应性 | Ni, M. | PDF | N/A | Epigenetic phase variation in the gut microbiome enhances bacterial adaptation | | 以下是这段英文的中文翻译：

"禁食后屠宰期间荷斯坦×安格斯杂交牛胃肠道微生物群的特征分析"

翻译说明： - Characterization：特征分析，指对某事物进行详细描述和分析。 - Gastrointestinal Tract：胃肠道，指动物的消化系统。 - Holstein x Angus Cross Cattle：荷斯坦×安格斯杂交牛，指荷斯坦奶牛与安格斯肉牛的杂交品种。 - Microbiome：微生物群，指生活在特定环境中的微生物群落。 - During Harvest after Feed Withdrawal：禁食后屠宰期间，指在停止喂食后到屠宰这一时间段。

希望这个翻译对你有帮助！如果有其他问题，欢迎随时提问。 | Costello, M. K. | PDF | N/A | Characterization of the Gastrointestinal Tract Holstein x Angus Cross Cattle Microbiome During Harvest after Feed Withdrawal | | 一种双特异性抗体克服了先前策略的局限性，实现了有效且肿瘤选择性的死亡受体5（DR5）聚集。 | Goldmacher, V. S. | PDF | N/A | A bispecific antibody overcomes limitations of prior strategies to achieve effective and tumor-selective Death Receptor 5 (DR5) clustering | | 由于自噬流受损，细胞外基质机械信号（失调）调节代谢氧化还原稳态。 | Gerardo, H. | PDF | N/A | Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux | | 节点信号（Nodal）与Wnt信号之间的时间协调控制着哺乳动物体型的形成。 | Dias, A. | PDF | N/A | A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan | | 从时间序列推断微生物群落中的资源竞争 | Chen, X. | PDF | N/A | Inferring resource competition in microbial communities from time series | | 温带热浪对昆虫活动昼夜节律的影响：跨栖息地的比较 | Carter, J. | PDF | N/A | Effects of a temperate heatwave on diel rhythms of insect activity: a comparison across habitats | | 宿主回避和抗性各自独立变化，并且对寄生虫基因型具有特异性。 | Amoroso, C. R. | PDF | N/A | Host avoidance and resistance vary independently and are specific to parasite genotype | | 翻转一些变异最慢基因组的开关：在msh1突变体中直接测量植物线粒体和质体突变率 | Broz, A. K. | PDF | N/A | Flipping the switch on some of the slowest mutating genomes: Direct measurements of plant mitochondrial and plastid mutation rates in msh1 mutants | | 人类三维染色质对与心脏病相关的转录因子的剂量依赖性敏感性 | Grant, Z. L. | PDF | N/A | Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor | | 手动与自动注释转座子元素的比较：以果蝇（Drosophila melanogaster）和白纹伊蚊（Aedes albopictus）为例，平衡准确性与生物学相关性 | Carrasco-Valenzuela, T. | PDF | N/A | Manual versus automatic annotation of transposable elements: case studies in Drosophila melanogaster and Aedes albopictus, balancing accuracy and biological relevance | | 一种新型广谱抗生素通过双结合靶点针对多重耐药细菌，且未检测到耐药性。 | He, W. | PDF | N/A | A novel broad-spectrum antibiotic targets multiple-drug-resistant bacteria with dual binding targets and no detectable resistance | | 使用超声波进行微气泡液滴的可编程组装与操控 | Fonseca, A. D. C. | PDF | N/A | Programmable Assembly and Steering of Microbubble Droplets using Ultrasound | | TFBSFootprinter：一种用于预测脊椎动物物种中转录因子结合位点的多组学工具 | Barker, H. | PDF | N/A | TFBSFootprinter: a multiomics tool for prediction of transcription factor binding sites in vertebrate species | | 内在神经时间尺度如何与事件相关活动相关联——柱内连接的关键作用 | Catal, Y. | PDF | N/A | How Intrinsic Neural Timescales Relate To Event-Related Activity - Key Role For Intracolumnar Connections | | 跨前额叶皮层和纹状体的基于模型和无模型强化学习的神经特征 | Miranda, B. | PDF | N/A | Neural signatures of model-based and model-free reinforcement learning across prefrontal cortex and striatum | | 改变的微小RNA表达与由多微生物感染引起的TLR2/4依赖性牙周炎症和骨吸收减少相关 | Jeepipalli, S. | PDF | N/A | Altered microRNA Expression Correlates with Reduced TLR2/4-Dependent Periodontal Inflammation and Bone Resorption Induced by Polymicrobial Infection | | 胆固醇缺乏引导自噬依赖性细胞外囊泡的分泌 | Yaeger, J. D. | PDF | N/A | Cholesterol deficiency directs autophagy-dependent secretion of extracellular vesicles | | 身体活动与久坐刺激的趋近与回避倾向的神经相关性：一项功能性磁共振成像研究 | Cheval, B. | PDF | N/A | Neural correlates of approach and avoidance tendencies toward physical activity and sedentary stimuli: An fMRI study | | 单胺诱导的二酰甘油信号迅速在纳米簇中积累Unc13，以实现快速的突触前增强。 | Blaum, N. | PDF | N/A | Monoamine-induced diacylglycerol signaling rapidly accumulates Unc13 in nanoclusters for fast presynaptic potentiation | | OPTN保护视网膜神经节细胞并改善视神经病变中的神经炎症。 | Wang, Q. | PDF | N/A | OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies | | 经颅磁刺激（TMS）诱发电位对皮层中电场方向的依赖性 | Grano, I. | PDF | N/A | The dependency of TMS-evoked potentials on electric-field orientation in the cortex | | 使用脑电图超扫描技术对石头剪刀布竞争决策的神经解码 | Moerel, D. | PDF | N/A | Neural decoding of competitive decision-making in Rock-Paper-Scissors using EEG hyperscanning | | 转基因A53T小鼠的多巴胺和纹状体区域存在星形胶质细胞的α-突触核蛋白聚集。 | Peat, C. | PDF | N/A | Transgenic A53T mice have astrocytic α-synuclein aggregates in dopamine and striatal regions | | 理解超声波神经调控的高阶网络可塑性机制 | Gatica, M. | PDF | N/A | Understanding the high-order network plasticity mechanisms of ultrasound neuromodulation | | 长期在果蝇中进行多通道记录的研究揭示，与清醒状态相比，果蝇在睡眠期间对异常视觉刺激的反应存在显著差异。 | van Swinderen, B. | PDF | N/A | Long-term multichannel recordings in Drosophila flies reveal distinct responses to deviant visual stimuli during sleep compared to wake | | 增强老年人和听力损失患者的神经语音追踪：随机共振的作用 | Herrmann, B. | PDF | N/A | Enhanced Neural Speech Tracking in Aging and Hearing Loss: The Role of Stochastic Resonance | | 鉴定人类细胞中复制应激反应的关键因素 | Janssen, L. M. E. | PDF | N/A | Identification of critical factors of the replication stress response in human cells | | 肌球蛋白-IC（Myosin-IC）的高分辨率结构揭示了一种独特的肌动蛋白结合方向、ADP释放途径以及动力冲程轨迹。 | Chavali, S. S. | PDF | N/A | High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory | | 巨型KASH蛋白与核糖体协同作用在体内建立细胞质生物物理特性 | Ding, X. | PDF | N/A | Giant KASH proteins and ribosomes synergistically establish cytoplasmic biophysical properties in vivo | | 竞争性信号通路控制电趋化 | Kulkarni, S. | PDF | N/A | Competing signaling pathways controls electrotaxis | | 通过高时间分辨率的荧光寿命光度法对快速和慢速神经元信号进行绝对测量 | Lodder, B. | PDF | N/A | Absolute measurement of fast and slow neuronal signals with fluorescence lifetime photometry at high temporal resolution | | 通过cryoCLEM引导的cryoET技术可视化的记忆印迹突触的三维分子结构 | Lovatt, C. | PDF | N/A | Memory engram synapse 3D molecular architecture visualized by cryoCLEM-guided cryoET | | PKD3定位于晚期内体，以维持依赖于Rab7的内溶酶体稳态。 | Gutierrez-Galindo, E. | PDF | N/A | PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomalhomeostasis | | 扩展了明亮且光稳定的细胞器钙离子传感器的调色板 | Moret, A. | PDF | N/A | An expanded palette of bright and photostable organellar Ca2+ sensors | | 基于图像的筛选识别内源性Dvl2生物分子凝聚体的调控因子 | Schubert, A. | PDF | N/A | Image-based screens identify regulators of endogenous Dvl2 biomolecular condensates | | 睡眠增加了大脑生理脉动的传播速度 | Elabasy, A. | PDF | N/A | Sleep increases propagation speed of physiological brain pulsations | | 从区域脑剖面构建结构和功能脑网络 | Song, D. | PDF | N/A | Constructing structural and functional brain networks from regional brain profiles | | 通过背侧前扣带回克服骄傲是接受不公平提议的基础 | Numano, S. | PDF | N/A | Overcoming pride via the dorsal ACC underlies acceptance of unfair offers | | 自动暗示和心理意象对社会情绪感知的偏见 | Myga, K. A. | PDF | N/A | Autosuggestion and Mental Imagery Bias the Perception of Social Emotions | | 阿普唑仑诱导雌性小鼠情境恐惧记忆的顺行性遗忘并改变背腹侧海马神经元群体活动。 | Kaplan, K. | PDF | N/A | Alprazolam induces anterograde amnesia for contextual fear memory and alters dorsoventral hippocampal neuronal ensembles in female mice | | 体育锻炼恢复由非严重性鼠疟疾破坏的神经认知稳态 | de Sousa, L. P. | PDF | N/A | PHYSICAL EXERCISE RESTORES NEUROCOGNITIVE HOMEOSTASIS DISRUPTED BY NON-SEVERE MURINE MALARIA | | 人类中缝背核活动信号行为策略的变化 | Priestley, L. | PDF | N/A | ACTIVITY IN HUMAN DORSAL RAPHE NUCLEUS SIGNALS CHANGES IN BEHAVIOURAL POLICY | | 基于尖峰时间响应曲线的脉冲耦合振荡器的平均场理论 | Canavier, C. C. | PDF | N/A | A Mean Field Theory for Pulse-Coupled Oscillators based on the Spike Time Response Curve | | 交感神经轴突的再生失败是导致神经损伤后功能恢复缺陷的原因之一。 | Tian, T. | PDF | N/A | Regenerative failure of sympathetic axons contributes to deficits in functional recovery after nerve injury | | 射血分数保留型心力衰竭中血管对认知障碍的贡献：TRPV4和KLF2作为ZSF1模型中神经血管功能障碍的关键介质 | Lambrichts, S. M. P. | PDF | N/A | Vascular contribution to cognitive impairment in heart failure with preserved ejection fraction: TRPV4 and KLF2 as key mediators of neurovascular dysfunction in the ZSF1 model | | 来自心肌梗死模型的透明大鼠心脏中胶原纤维的深层组织二次谐波 | Matsuyama, M. | PDF | N/A | Deep Tissue Second-Harmonics of Collagen Fibers in a Transparent Rat Heart from a Myocardial Infarction Model | | 建立一个临床前慢性伤口模型以表征蛇咬伤中毒的病理生理学 | Dawson, C. A. | PDF | N/A | Establishing a preclinical chronic wound model to characterise the pathophysiology of snakebite envenoming | | 正弦调节去噪昼夜节律机制 | Kaji, H. | PDF | N/A | Sinusoidal regulation denoises circadian machinery | | 生物膜基质保护枯草芽孢杆菌免受过氧化氢的侵害。 | Muratov, E. | PDF | N/A | The biofilm matrix protects Bacillus subtilis against hydrogen peroxide | | 皮质类固醇耐药性在急性移植物抗宿主病（Graft Versus Host Disease, GVHD）发作时由早期免疫反应动态预先决定。 | Le Grand, S. | PDF | N/A | Corticosteroid resistance is predetermined by early immune response dynamics at acute Graft Versus Host disease onset | | 在协作交叉小鼠品系中进行遗传定位，识别出影响可卡因初始敏感性的基因位点。 | Schoenrock, S. A. | PDF | N/A | Genetic mapping in Collaborative Cross mouse strains identifies loci that affect initial sensitivity to cocaine | | 稀疏测序技术允许对全基因组范围内的胞嘧啶修饰水平进行精确且高效的量化。 | Loo, C. E. | PDF | N/A | Sparse Sequencing permits accurate and efficient quantification of genome-wide cytosine modification levels |

BioRxiv 2025-01-11 Papers

标题	作者	PDF链接	代码仓库	Title
海马体似乎并不是丘脑核团reuniens的主要目标。	Andrianova, L.	PDF	N/A	Hippocampus does not appear to be a major target of thalamic nucleus reuniens
视听提示必须是可预测的，并且与获胜配对，以驱动风险选择。	Hathaway, B. A.	PDF	N/A	Audiovisual cues must be predictable and win-paired to drive risky choice
通过对同基因FUS和TARDBP肌萎缩侧索硬化症（ALS）细胞系进行单细胞RNA测序，发现了一种仅在运动神经元中出现的早期线粒体功能障碍，这种功能障碍在两种ALS模型中均存在。	Schweingruber, C.	PDF	N/A	Single-cell RNA sequencing across isogenic FUS and TARDBP ALS lines reveals a shared early mitochondrial dysfunction unique to motor neurons.
从受精到定居的珊瑚-藻类共生代谢动态揭示了珊瑚能量脆弱性的关键点	Huffmyer, A. S.	PDF	N/A	Metabolic dynamics of the coral-algal symbiosis from fertilization to settlement identify critical coral energetic vulnerabilities
BIBSNet：一种用于MRI扫描的深度学习婴儿图像脑部分割网络	Hendrickson, T. J.	PDF	N/A	BIBSNet: A Deep Learning Baby Image Brain Segmentation Network for MRI Scans
通过感觉运动系统对听觉皮层活动的抑制作用来减轻耳鸣	Schmitt, A.	PDF	N/A	Reducing tinnitus via inhibitory influence of the sensorimotor system on auditory cortical activity
基因组大小进化与表型相关性在箭毒蛙科（Dendrobatidae）中的研究	Douglas, T. E.	PDF	N/A	Genome size evolution and phenotypic correlates in the poison frog family Dendrobatidae
以下是这段文字的中文翻译：

人类大脑中全稳态-内感受系统的皮层和皮层下映射：使用7特斯拉功能磁共振成像进行复制和扩展

翻译说明： - Cortical and subcortical mapping：皮层和皮层下映射 - allostatic-interoceptive system：全稳态-内感受系统 - 7 Tesla fMRI：7特斯拉功能磁共振成像 - replication and extension：复制和扩展

希望这对你有帮助！如果有其他问题，请随时告诉我。 | Zhang, J. | PDF | N/A | Cortical and subcortical mapping of the allostatic-interoceptive system in the human brain: replication and extension with 7 Tesla fMRI | | 来自连接蛋白Afadin和ZO-1的PDZ结构域作为机械传感器 | Vachharajani, V. T. | PDF | N/A | PDZ Domains from the Junctional Proteins Afadin and ZO-1 Act as Mechanosensors | | C末端标记会损害AGO2的功能 | Shah, K. M. | PDF | N/A | C-terminal tagging impairs AGO2 function | | 算法代理中的结构化动态 | Ruffini, G. | PDF | N/A | Structured dynamics in the algorithmic agent | | 减弱ABHD17同工型可增强NOD2及其部分与克罗恩病相关的NOD2变体的S-酰化及其功能。 | Dixon, C. | PDF | N/A | Attenuating ABHD17 isoforms augments the S-acylation and function of NOD2 and a subset of Crohns disease-associated NOD2 variants. | | 高密度脂蛋白的脂质组和蛋白质组在更年期发生改变。 | Lehti, S. | PDF | N/A | The lipidome and proteome of high-density lipoprotein are altered in menopause | | 预训练的Maldi Transformers提升了基于MALDI-TOF MS的预测效果 | De Waele, G. | PDF | N/A | Pre-trained Maldi Transformers improve MALDI-TOF MS-based prediction | | 白蜡树（Fraxinus）物种的遗传条形码及新型宽杂交种的生成 | Plumb, W. | PDF | N/A | Genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids | | 专家导航员采用基于理性的复杂性决策预缓存技术，用于大规模现实世界规划 | Fernandez Velasco, P. | PDF | N/A | Expert Navigators Deploy Rational Complexity-Based Decision Precaching for Large-Scale Real-World Planning | | 复制性聚合酶γ的外切酶活性驱动损伤诱导的线粒体DNA清除 | Seshadri, A. | PDF | N/A | Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance | | 建模大鼠心脏活动的时间分辨调制：一项关于药物自主神经刺激的研究 | Candia-Rivera, D. | PDF | N/A | Modeling the time-resolved modulations of cardiac activity in rats: A study on pharmacological autonomic stimulation | | 感觉运动延迟限制了果蝇行走三维运动学模型中的稳健运动 | Karashchuk, L. | PDF | N/A | Sensorimotor delays constrain robust locomotion in a 3D kinematic model of fly walking | | 术前脑部映射预测重要功能区肿瘤切除后的语言结果 | Muir, M. | PDF | N/A | Preoperative Brain Mapping Predicts Language Outcomes after Eloquent Tumor Resection | | 密切相关的兼性和专性CAM表型在亚属铁兰（Tillandsia）中，在水分胁迫下激活了不同的转录反应。 | Groot Crego, C. | PDF | N/A | Closely related facultative and constitutive CAM phenotypes activate different transcriptional responses upon water withholding in the subgenus Tillandsia | | GATA6调控WNT和BMP信号通路，在人类心脏发生的最初阶段对前心脏中胚层进行模式化调控。 | Bisson, J. A. | PDF | N/A | GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis | | 对人类所有旁系同源基因对进行遗传定位以表征合成致死性和缓冲效应 | Flister, M. J. | PDF | N/A | Genetic Mapping of All Human Paralog Pairs to Characterize Synthetic Lethality and Buffering | | 从小鼠脊髓钙成像数据推断尖峰率 | Rupprecht, P. | PDF | N/A | Spike rate inference from mouse spinal cord calcium imaging data | | 巨噬细胞中脂肪酸的摄取或分解代谢受损会限制结核分枝杆菌的细胞内生长。 | Simwela, N. V. | PDF | N/A | Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis | | 由雄性间竞争塑造的不同日常时间生态位的演化可以导致同域物种形成。 | Bouinier, T. | PDF | N/A | Evolution of divergent daily temporal niches shaped by male-male competition can generate sympatric speciation | | 贝叶斯p曲线混合模型作为区分效应大小和效应普遍性的工具 | Veillette, J. P. | PDF | N/A | Bayesian p-curve Mixture Models as a Tool to Dissociate Effect Size and Effect Prevalence | | 空间相关数据的差异表达分析 | Vasconcelos, A. G. | PDF | N/A | Differential Expression Analysis for Spatially Correlated Data | | 产前高钙饮食供应对奶绵羊和奶山羊的骨稳态及后代生长的影响 | Brugger, D. | PDF | N/A | Antepartum high dietary supply of calcium affects bone homeostasis and offspring growth in dairy sheep and dairy goats | | 通过在睡眠中进行提示来塑造运动学习的结构动态 | Stee, W. | PDF | N/A | Shaping the structural dynamics of motor learning through cueing during sleep | | 野生鸦科动物学会社会容忍以利用新信息 | Arbon, J. J. | PDF | N/A | Wild corvids learn social tolerance to exploit new information | | 大豆作为对土壤碱性和干旱共同影响的适应性反应的生理和转录变化 | Hasan, M. R. | PDF | N/A | Physiological and transcriptional changes in soybean as adaptive responses to the combined effects of soil alkalinity and drought | | 广谱免疫抑制编码于自扩增RNA中，可实现非细胞毒性、非免疫刺激、外部可控的转基因表达。 | Lim, T. K. Y. | PDF | N/A | Broad-spectrum immune suppression encoded in self-amplifying RNA enables non-cytotoxic, non-immunostimulatory, externally controllable transgene expression | | 通过拓扑高阶功能连接揭示精神分裂症中的整合-分离失衡 | Li, Q. | PDF | N/A | Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity | | 以下是这段英文的中文翻译：

计算洞察由C肽驱动的迷你前胰岛素原的变构行为

这个翻译保留了原文的科学术语和结构，同时使其更符合中文的表达习惯。 | AYAN, E. | PDF | N/A | Computational Insights into the Allosteric Behavior of Mini Proinsulin Driven by C Peptide Mobility | | 在HA(pY)STACK中搜索磺酸酪氨酸（sY） | Tzvetkov, J. | PDF | N/A | Searching for Sulfotyrosines (sY) in a HA(pY)STACK | | 序列终止信号通过多巴胺介导的信用分配驱动习惯形成 | Magnard, R. | PDF | N/A | Sequence termination cues drive habits via dopamine-mediated credit assignment | | 连接蛋白43介导的线粒体转移可预防顺铂诱导的感觉神经退行性病变。 | Owen, R. | PDF | N/A | Connexin 43 mediated mitochondrial transfer prevents cisplatin induced sensory neurodegeneration. | | 空间交易场所：提高位置分辨率会降低海马编码中的上下文容量 | Rooke, S. | PDF | N/A | Trading Place for Space: Increasing Location Resolution Reduces Contextual Capacity in Hippocampal Codes | | 小脑性共济失调对运动学和动力学需求的敏感性 | Oh, K. | PDF | N/A | Sensitivity of Cerebellar Reaching Ataxia to Kinematic and Dynamic Demands | | 熊蜂对氨基酸的味觉敏感性 | Rossoni, S. | PDF | N/A | Gustatory sensitivity to amino acids in bumblebees | | EOR-1/PLZF调控的WAH-1/AIF依次促进非凋亡性细胞残骸清除的早期和晚期阶段 | Rather, N. | PDF | N/A | EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removal | | 准确且通用的DNA表征从大规模基因组基础模型中涌现 | Ellington, C. N. | PDF | N/A | Accurate and General DNA Representations Emerge from Genome Foundation Models at Scale | | GraphVelo 能够准确推断单细胞的多模态速度和分子机制。 | Chen, Y. | PDF | N/A | GraphVelo allows for accurate inference of multimodal velocities and molecular mechanisms for single cells | | 简化与冗余：睡眠期间预测错误的信息处理 | Blume, C. | PDF | N/A | Reduced and Redundant: Information Processing of Prediction Errors during Sleep | | 伤寒沙门氏菌的伤寒毒素在急性伤寒期间引发宿主的抗菌反应。 | Srour, S. | PDF | N/A | Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever | | 蚊子会根据微孢子虫感染的动态自我治疗 | Zeferino, T. G. | PDF | N/A | Mosquitoes self-medicate according to the dynamics of a microsporidian infection | | PinkyCaMP是一种基于mScarlet的钙离子传感器，具有卓越的亮度、光稳定性和多重检测能力。 | Fink, R. | PDF | N/A | PinkyCaMP a mScarlet-based calcium sensor with exceptional brightness, photostability, and multiplexing capabilities | | 手部伸展过程中对表面运动的不完全适应 | Balestrucci, P. | PDF | N/A | Incomplete adaptation to surface movement during hand reaching | | 磁粒子成像技术的进展：评估磁性微球及优化采集参数以实现高灵敏度细胞追踪 | Flood, S. N. | PDF | N/A | Advances in magnetic particle imaging: evaluating magnetic microspheres and optimized acquisition parameters for high sensitivity cell tracking | | 肥胖中血管生成信号的综合分析：毛细血管特征与VEGF结合动力学 | Lee, Y. | PDF | N/A | Integrative analysis of angiogenic signaling in obesity: capillary features and VEGF binding kinetics | | PRC1通过两种不同的阻力模式抵抗微管滑动，这是由于重叠微管之间间距的变化所致。 | Steckhahn, D. | PDF | N/A | PRC1 resists microtubule sliding in two distinct resistive modes due to variations in the separation between overlapping microtubules | | 胰岛素中的变构残基动力学：温度诱导从双六聚体向六聚体集体运动的转变 | Ayan, E. | PDF | N/A | Allosteric Residue Dynamics in Insulin: Temperature Induces Shift from Dihexamer to Hexamer Collective Motion | | C12ORF57：突触AMPA电流和兴奋性神经元稳态的新型主要调节因子 | Jiang, R. | PDF | N/A | C12ORF57: a novel principal regulator of synaptic AMPA currents and excitatory neuronal homeostasis | | 对白色念珠菌中CRISPR-Cas9等位基因编辑系统的比较评估：在一种具有挑战性的病原体中进行的研究 | Sofras, D. | PDF | N/A | A comparative evaluation of CRISPR-Cas9 allele editing systems in Candida auris: challenging research in a challenging bug | | 以下是这段英文的中文翻译：

香蕉（Musa acuminata）WRKY基因家族的密码子使用偏好性分析

翻译说明： - Codon Usage Bias Analysis 翻译为“密码子使用偏好性分析”，指的是对基因序列中密码子使用频率的研究。 - WRKY Gene Family 翻译为“WRKY基因家族”，WRKY是一类植物中常见的转录因子家族。 - Musa acuminata 是香蕉的学名，翻译为“香蕉”或“小果野蕉”。

pH响应性内在无序肽的相分离动力学

翻译解释： - "pH-Responsive" 翻译为 "pH响应性"，表示对pH值变化有响应的特性。 - "Phase Separation" 翻译为 "相分离"，指的是物质从均匀混合物中分离成不同相的过程。 - "Dynamics" 翻译为 "动力学"，表示系统的动态行为或变化过程。 - "Intrinsically Disordered Peptides" 翻译为 "内在无序肽"，指的是没有固定三维结构的肽链。

血浆驱动的生物催化利用细胞色素P450酶CYP152BSβ

翻译解释： - Plasma-driven：血浆驱动的 - biocatalysis：生物催化 - cytochrome P450 enzyme：细胞色素P450酶 - CYP152BSβ：CYP152BSβ（一种特定的细胞色素P450酶）

白色念珠菌的化学蛋白质组学分析用于抗真菌激酶抑制剂的表征

翻译说明： - "Chemoproteomic Profiling" 翻译为“化学蛋白质组学分析”，这是一种结合化学探针和蛋白质组学技术的研究方法。 - "C. albicans" 是“白色念珠菌”的学名，是一种常见的真菌病原体。 - "Characterization" 翻译为“表征”，指对物质或化合物的性质和功能进行详细描述和分析。 - "Anti-fungal Kinase Inhibitors" 翻译为“抗真菌激酶抑制剂”，指能够抑制真菌中激酶活性的化合物，可能用于抗真菌药物的开发。

加拉帕戈斯群岛上野生番茄物种的流行与入侵动态：基于两个世纪的采集记录

这个标题描述了一项研究，旨在通过分析过去两个世纪的采集记录，探讨加拉帕戈斯群岛上野生番茄物种的分布、流行以及可能的入侵动态。 | Kutza, A. D. | PDF | N/A | Endemic and invasion dynamics of wild tomato species on the Gal&aacutepagos Islands, across two centuries of collection records | | 利用超敏感人类TRPV1通道在盲人视网膜中实现红外光检测的工程研究 | Chevalier, M. | PDF | N/A | Engineering Infrared Light Detection in Blind Human Retina Using Ultrasensitive Human TRPV1 Channels | | 大肠杆菌外膜囊泡封装小分子抗生素通过促进运输改善药物功能 | Wu, M. | PDF | N/A | Escherichia coli outer membrane vesicles encapsulating small molecule antibiotics improve drug function by facilitating transport | | 南极光合作用：硅藻Chaetoceros Simplex中的能量转移与电荷分离 | Lee, S. E. | PDF | N/A | Antarctic photosynthesis: energy transfer and charge separation in the diatom Chaetoceros Simplex | | 解码控制下丘脑和前丘脑神经元发育的基因网络。 | Kim, D. W. | PDF | N/A | Decoding Gene Networks Controlling Hypothalamic and Prethalamic Neuron Development. | | 刺激同步的BOLD振荡的注意增强和抑制 | Rafeh, R. W. | PDF | N/A | Attentional enhancement and suppression of stimulus-synchronized BOLD oscillations | | 通过温度感应而非活动感应对运动回路进行稳态调节 | Cannon, D. | PDF | N/A | Homeostatic regulation of a motor circuit through temperature sensing rather than activity sensing | | 人类可以在不平坦的地形上经济地行走，而无需通过复杂的优化过程，只需采用简单的反馈控制策略即可实现。 | Darici, O. | PDF | N/A | Humans can walk economically on uneven terrain without deliberative optimization with a Simple Feedback Control Policy | | 全身协同动作反映了运动攀岩的专业水平。 | Maselli, A. | PDF | N/A | Whole-body coarticulation reflects expertise in sport climbing | | 年轻人和老年人在行走时对前向与后向平衡干扰的感知风险 | Jain, S. | PDF | N/A | Perceived risk of forward versus backward balance disturbances while walking in young and older adults | | 层1 NDNF中间神经元在自由行为小鼠的睡眠期间形成了具有相反激活模式的独特亚群。 | Brecier, A. | PDF | N/A | Layer 1 NDNF interneurons form distinct subpopulations with opposite activation patterns during sleep in freely behaving mice | | 从点到条纹：通过调节反应扩散系统及其预模式，猴面花色素模式的进化 | Liang, M. | PDF | N/A | From spots to stripes: Evolution of pigmentation patterns in monkeyflowers via modulation of a reaction-diffusion system and its prepatterns | | 测试睾丸广泛转录功能 | Kumon, T. | PDF | N/A | Testing the function of widespread transcription of the testis | | 在精子发生过程中，特定位点的DNA去甲基化为小鼠精子中核小体保留的位点预设了条件。 | Maezawa, S. | PDF | N/A | Site-specific DNA demethylation during spermatogenesis presets the sites of nucleosome retention in mouse sperm | | 小鼠体节发生的尺度化通过细胞周期与分割时钟振荡的耦合实现 | van Oostrom, M. v. | PDF | N/A | Scaling of mouse somitogenesis by coupling of cell cycle to segmentation clock oscillations | | 抗癫痫药物对已建立癫痫模型的雄性大鼠开放场探索的急性剂量相关效应 | WU, Q. | PDF | N/A | Acute Dose-Related Effect of Antiseizure Medicines on Open Field Exploration of Male Rats with Established Epilepsy | | 量化神经群体活动差异的形状度量方法 | Barbosa, J. | PDF | N/A | Quantifying Differences in Neural Population Activity With Shape Metrics | | 溶剂、性别和年龄对小鼠吸入大麻提取物药代动力学及急性行为效应的影响 | Wesbrook, S. R. | PDF | N/A | Influence of solvent, sex, and age on pharmacokinetic and acute behavioral effects of vaporized cannabis extract in mice | | 注意力调节神经特征维度图中的刺激表征 | Thayer, D. D. | PDF | N/A | Attention Modulates Stimulus Representations in Neural Feature Dimension Maps | | 非人类灵长类海马中细胞共振的胆碱能调节 | Gambrill, A. | PDF | N/A | CHOLINERGIC MODULATION OF CELLULAR RESONANCE IN NON-HUMAN PRIMATE HIPPOCAMPUS | | 帕金森病中冻结步态的下丘脑特征 | Collomb-Clerc, A. | PDF | N/A | Subthalamic Signature of Freezing of Gait in Parkinson Disease | | 通过D-对映体水凝胶工程实现的细胞内张力松弛，调控神经生成和免疫调节，以促进脊髓修复。 | Li, Y. | PDF | N/A | Intracellular tension relaxation engineered through D-enantiomeric hydrogel maneuvers neurogenesis and immunomodulation to facilitate spinal cord repair | | 增强子动态与空间组织驱动人类脊髓中解剖学受限的细胞状态 | Kandror, E. K. | PDF | N/A | Enhancer Dynamics and Spatial Organization Drive Anatomically Restricted Cellular States in the Human Spinal Cord | | 神经认知效率评分：一种结合同步电生理和行为数据的新方法的推导、验证及应用 | Wenger, M. J. | PDF | N/A | The Neurocognitive efficiency score: Derivation, validation, and application of a novel combination of concurrent electrophysiological and behavioral data | | 未突变的人类tau蛋白以依赖小胶质细胞的方式刺激阿尔茨海默病相关的神经退行性变。 | Roy, E. | PDF | N/A | Non-mutated human tau stimulates Alzheimer's disease-relevant neurodegeneration in a microglia-dependent manner | | 呼吸在多感官整合过程中促进了行为表现。 | Saltafossi, M. | PDF | N/A | Respiration facilitates behaviour during multisensory integration | | 在雄性大鼠的昼夜节律性松果体中寻找小胶质细胞的节律模式 | Freites, C. L. | PDF | N/A | Seeking rhythmic patterns in microglial cells within the circadian pineal gland from male rats | | 识别和分类小鼠晶状体中丰富的RNA结合蛋白，以及Carhsp1、Igf2bp1/ZBP1和Ybx1与晶状体蛋白和β-肌动蛋白mRNA的相互作用 | Rayee, D. | PDF | N/A | Identification and classification of abundant RNA-binding proteins in the mouse lens and interactions of Carhsp1, Igf2bp1/ZBP1, and Ybx1 with crystallin and β-actin mRNAs | | 在HCV感染期间cGAS-STING信号通路的激活 | Anwar, S. | PDF | N/A | Activation of cGAS-STING signaling pathway during HCV infection | | DNA修复对于霍乱弧菌在硫代硫酸盐-柠檬酸盐-胆盐-蔗糖（TCBS）培养基上的生长至关重要。 | Wessel, A. J. | PDF | N/A | DNA repair is essential for Vibrio cholerae growth on Thiosulfate-Citrate-Bile Salts-Sucrose (TCBS) Medium | | 单克隆纳米抗体改变酵母液泡H+-ATP酶的活性和组装 | Knight, K. | PDF | N/A | Monoclonal Nanobodies Alter the Activity and Assembly of the Yeast Vacuolar H+-ATPase |

BioRxiv 2025-01-10 Papers

标题	作者	PDF链接	代码仓库	Title
过表达受体样激酶BIR1基因会导致拟南芥中依赖SOBIR1和EDS1的细胞死亡表型。	Guzman-Benito, I.	PDF	N/A	Overexpression of the receptor-like kinase BIR1 gene causes SOBIR1- and EDS1-dependent cell death phenotypes in Arabidopsis
猴痘病毒在细胞间传播，并在人类神经类器官中导致神经元死亡。	Schultz-Pernice, I.	PDF	N/A	Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids
解码人类大脑中观察到的动作的物理原理	Wurm, M. F.	PDF	N/A	Decoding the physics of observed actions in the human brain
撤回：伽马疱疹病毒感染改变了转移RNA的剪接并引发tRNA的切割	Manning, A. C.	PDF	N/A	WITHDRAWN: Gammaherpesvirus infection alters transfer RNA splicing and triggers tRNA cleavage
超灵敏元蛋白质组学重新定义了肠道暗元蛋白质组，揭示了肠道炎症性疾病中的宿主-微生物组相互作用及药物靶点。	Xian, F.	PDF	N/A	Ultra-sensitivity metaproteomics redefines the gut dark metaproteome, uncovering host-microbiome interactions and drug targets in intestinal inflammatory diseases.
撤回：人为电磁场对地磁位移鳐鱼行为的影响	NEWTON, K.	PDF	N/A	WITHDRAWN: The Effects of Anthropogenic Electromagnetic Fields on the Behavior of Geomagnetically Displaced Skates
通过使用自发的视网膜活动对人工神经网络进行预训练，可以提高其在自然场景中的运动预测能力。	May, L.	PDF	N/A	Pre-training artificial neural networks with spontaneous retinal activity improves motion prediction in natural scenes
通过研究柳枝稷中多个因素来优化复杂性状的基因组预测	Wang, P.	PDF	N/A	Optimizing genomic prediction for complex traits via investigating multiple factors in switchgrass
以下是这段文字的中文翻译：

受驱动蛋白和原肌球蛋白马达失调影响的收缩性细胞骨架结构的瞬时流动分析

短柄草根系结构和解剖对硝酸盐和铵盐适应性的调控分析

翻译说明： - "Regulatory Analysis" 翻译为 "调控分析"，表示对某种调控机制的研究。 - "Root Architectural and Anatomical Adaptation" 翻译为 "根系结构和解剖适应性"，指植物根系在形态和解剖上的适应性变化。 - "Nitrate and Ammonium" 翻译为 "硝酸盐和铵盐"，是两种常见的氮源形式。 - "Brachypodium distachyon" 是植物学名，通常直接保留原文，或翻译为 "短柄草"。

希望这段翻译对你有帮助！ | Rouina, H. | PDF | N/A | Regulatory Analysis of Root Architectural and Anatomical Adaptation to Nitrate and Ammonium in Brachypodium distachyon | | 多发性硬化症类器官中的髓鞘形成受损：p21将少突胶质细胞功能障碍与疾病亚型联系起来 | Daviaud, N. | PDF | N/A | Impaired Myelination in Multiple Sclerosis Organoids: p21 Links Oligodendrocyte Dysfunction to Disease Subtype | | 成年人类未成熟神经元在健康衰老、阿尔茨海默病和认知韧性中的独特转录特征 | Tosoni, G. | PDF | N/A | Unique transcriptional profiles of adult human immature neurons in healthy aging, Alzheimer's disease, and cognitive resilience | | SARS-CoV-2 T细胞反应随多次COVID-19加强针接种的演变 | da Silva Antunes, R. | PDF | N/A | Evolution of SARS-CoV-2 T cell responses as a function of multiple COVID-19 boosters | | 牛呼吸道和乳腺上皮细胞对禽源和哺乳动物来源的2.3.4.4b分支H5N1高致病性禽流感病毒的易感性 | Meliopoulos, V. A. | PDF | N/A | Susceptibility of bovine respiratory and mammary epithelial cells to avian and mammalian derived clade 2.3.4.4b H5N1 highly pathogenic avian influenza viruses | | SAMHD1通过线粒体途径增强HIV-1诱导的单核细胞凋亡 | Yang, H. | PDF | N/A | SAMHD1 enhances HIV-1-induced apoptosis in monocytic cells via the mitochondrial pathway | | TERRA R环触发端粒维护机制向断裂诱导复制和依赖PrimPol的修复方向转变。 | Lingner, J. | PDF | N/A | TERRA R-loops trigger a switch in telomere maintenance towards break-induced replication and PrimPol-dependent repair | | 通过多反应监测质谱法和QconCAT蛋白标准对溶酶体蛋白进行绝对定量 | Mosen, P. R. | PDF | N/A | Absolute Quantification of Lysosomal Proteins by Multiple Reaction Monitoring Mass Spectrometry and QconCAT Protein Standards | | 群体遗传学中模型变异下的选择和时序推断的稳健性 | Escabi, J. | PDF | N/A | Robustness of Selection and Timing Inference under Model Variation in Population Genetics | | 基因组和宏基因组对微生物碳酸酐酶基因的调查揭示了新的进化分支、高度多样性以及生物群落特异性 | Franco, M. E. E. | PDF | N/A | Genomic and metagenomic survey of microbial carbonic anhydrase genes reveals novel clades, high diversity, and biome-specificity | | N6-甲基腺苷和NEXT复合物调控Xist RNA的降解与X染色体失活动力学 | Wei, G. | PDF | N/A | N6-methyladenosine and the NEXT complex direct Xist RNA turnover and X inactivation dynamics | | HAPLN2的聚集是小鼠大脑生理老化的一个标志，HAPLN2是周围结细胞外基质的一个组成部分。 | Watanabe, A. | PDF | N/A | Aggregation of HAPLN2, a component of the perinodal extracellular matrix, is a hallmark of physiological brain aging in mice | | Cas12a蛋白的桥螺旋的螺旋转变是R-loop形成和RuvC激活的变构调节因子。 | Ganguly, C. | PDF | N/A | Helical transition of the bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation | | CpgD是一种磷酸甘油酸胞苷酰转移酶，是合成神经酰胺二磷酸甘油酯所必需的。 | Dhakephalkar, T. | PDF | N/A | CpgD is a phosphoglycerate cytidylyltransferase required for ceramide diphosphoglycerate synthesis | | PrfH亚家族在拯救翻译过程中停滞的受损和完整核糖体的分子和结构基础 | Tian, Y. | PDF | N/A | Molecular and structural basis of a subfamily of PrfH rescuing both the damaged and intact ribosomes stalled in translation | | N端的无序-有序转变是IscU变构的关键决定因素。 | Na, J. | PDF | N/A | The N-terminal order-disorder transition is a critical determinant for a metamorphosis of IscU | | 拟杆菌目T6SS小亚基Hcp形成识别效应蛋白的异聚体。 | San-Miguel, S. G. | PDF | N/A | Bacteroidales T6SS minor Hcp subunits form heteromers recognising effectors | | 利用人类多能干细胞衍生的骨骼组装体模拟人类肢体骨骼发育 | Takao, T. | PDF | N/A | Modeling the human limb skeletal development using human pluripotent stem cell-derived skeletal assembloid | | 阿尔茨海默病对大脑结构和行为影响的全球性剖析：高分辨率磁共振成像揭示显著的区域效应

在这项研究中，我们通过高分辨率磁共振成像（MRH）技术，对阿尔茨海默病（Alzheimer's disease, AD）对大脑结构和行为的影响进行了全面的全球性剖析。研究结果表明，AD在大脑的不同区域产生了显著的影响，这些影响不仅体现在大脑结构的改变上，也反映在患者的行为和认知功能上。高分辨率MRH技术为我们提供了详细的大脑图像，使我们能够精确地识别和量化这些区域性的变化，从而更深入地理解AD的病理机制及其对患者生活质量的影响。 | Johnson, G. A. | PDF | N/A | Global dissection of the impact of Alzheimer's disease on brain architecture and behavior: High resolution MRH resolves robust regional effects | | 伏隔核中Shank3的缺乏揭示了社交特异性动机的丧失 | Folkes, O. M. | PDF | N/A | Deficiency of Shank3 in the Nucleus Accumbens Reveals a Loss of Social-Specific Motivation | | 中脑扩展杏仁核及其他社交行为网络中心的Otp谱系儿茶酚胺能神经元的发育 | Morales, L. | PDF | N/A | Development of catecholaminergic neurons of Otp-lineage in the medial extended amygdala and other centers of the social behavior network | | 在计算机编程指令后，前顶叶推理系统中逻辑算法表示的快速“循环利用” | Liu, Y.-F. | PDF | N/A | Rapid "recycling" of logical algorithm representations in fronto-parietal reasoning systems following computer programming instructions | | Replay在离线状态下构建了一个高效的认知地图，以避免在线计算。 | Ou, J. | PDF | N/A | Replay builds an efficient cognitive map offline to avoid computation online | | 人类皮质层中的预测性声学处理 | Faes, L. K. | PDF | N/A | Predictive acoustical processing in human cortical layers | | C12ORF57：突触AMPA电流和兴奋性神经元稳态的新型主要调节因子 | Jiang, R. | PDF | N/A | C12ORF57: a novel principal regulator of synaptic AMPA currents and excitatory neuronal homeostasis | | 神经板预模式化使得脊髓中中间神经前体细胞的特定化成为可能。 | Nandagopal, S. | PDF | N/A | Neural plate pre-patterning enables specification of intermediate neural progenitors in the spinal cord | | 以下是将“Generation and Characterization of a Knockout Mouse of an Enhancer of EBF3”翻译成中文的结果：

EBF3增强子的基因敲除小鼠的构建与表征

翻译说明： 1. "Optimization of Extraction Process by Response Surface Methodology" 翻译为 "响应面法优化提取工艺"，其中 "响应面法" 是常用的统计优化方法，"提取工艺" 指的是从原料中提取目标成分的过程。 2. "Total Flavonoids from Ziziphus Jujube Flesh" 翻译为 "大枣果肉总黄酮"，其中 "Ziziphus Jujube" 是 "大枣" 的学名，"Flesh" 指的是果肉部分，"总黄酮" 是指一类具有生物活性的化合物。 3. "Sedative-Hypnotic Effects" 翻译为 "镇静催眠作用"，指的是药物或化合物对中枢神经系统的抑制作用，能够帮助缓解焦虑和促进睡眠。

在这段翻译中，我尽量保持了原文的专业性和准确性。以下是对翻译的简要解释：

Cholesterol-Dependent 翻译为“胆固醇依赖性”，指的是与胆固醇相关的特性或过程。
Dimerization 翻译为“二聚化”，指的是两个分子（如蛋白质）结合形成一个二聚体的过程。
Conformational Dynamics 翻译为“构象动力学”，指的是分子在空间中的形状和结构随时间的变化。
EphA2 Receptors 翻译为“EphA2受体”，EphA2是一种特定的受体蛋白。
Insights from 翻译为“基于……的见解”，表示从某种方法或研究中得出的结论或理解。
Coarse-Grained and All-Atom Simulations 翻译为“粗粒化和全原子模拟”，这是两种不同的分子模拟方法，分别用于研究分子系统的不同层面。

希望这个翻译对您有帮助！如果有任何进一步的问题或需要更详细的解释，请随时告诉我。 | Sahoo, A. R. | PDF | N/A | Cholesterol-Dependent Dimerization and Conformational Dynamics of EphA2 Receptors: Insights from Coarse-Grained and All-Atom Simulations | | 稻曲病菌通过效应蛋白SCRE9促进赤霉素（GA）的生物合成，从而抑制植物的花部免疫反应。 | Yu, S. | PDF | N/A | Ustilaginoidea virens suppresses floral immunity through promoting GA biosynthesis by the effector SCRE9 | | EPISeg：利用开放获取的多中心数据对回波平面图像上的脊髓进行自动分割 | Banerjee, R. | PDF | N/A | EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data | | 一种通过鼻内递送的纳米脂质载体（NLC）传递的自扩增RNA疫苗，能够建立对预流行H5N1和H7N9流感病毒的保护性免疫。 | Ykema, M. R. | PDF | N/A | An intranasal, NLC-delivered self-amplifying RNA vaccine establishes protective immunity against pre-pandemic H5N1 and H7N9 influenza | | 对恒河猴免疫球蛋白基因座变异的广泛调查与功能分析 | Peres, A. | PDF | N/A | A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques | | 温度对蚊子寄生虫感染的非线性效应在广阔的地理气候梯度上的研究 | Farner, J. E. | PDF | N/A | Nonlinear effects of temperature on mosquito parasite infection across a large geographic climate gradient | | 土壤特性的时空变化预测大陆尺度上的植物健康状况 | Wang, N. | PDF | N/A | Spatiotemporal changes in soil properties predict plant health at continental scale | | 使用直线连分数的生物生长模型 | S, S. I. | PDF | N/A | A Biological Growth Model using Continued Fraction of Straight Lines | | 多样性、连通性和负相互作用定义了跨越陆地、溪流和海洋的强大微生物组网络。 | Kajihara, K. T. | PDF | N/A | Diversity, connectivity and negative interactions define robust microbiome networks across land, stream, and sea | | 丝氨酸蛋白酶抑制剂（serpin）基因的串联重复产生了功能变异和蛇毒抑制剂。 | Ward, M. S. | PDF | N/A | Tandem duplication of serpin genes yields functional variation and snake venom inhibitors. | | 一种风媒传粉的草本植物中雌雄异株现象的解释：基于性别分配上的分裂选择 | Chen, K.-H. | PDF | N/A | Dioecy in a wind-pollinated herb explained by disruptive selection on sex allocation | | PARAS：非核糖体肽合成酶底物特异性的高精度机器学习 | Terlouw, B. R. | PDF | N/A | PARAS: high-accuracy machine-learning of substrate specificities in nonribosomal peptide synthetases | | 使用FlexConsensus算法将构象景观合并到一个单一的共识空间中 | Herreros, D. | PDF | N/A | Merging conformational landscapes in a single consensus space with FlexConsensus algorithm | | BellaVista：基于成像的空间转录组学开源可视化工具 | Coles, A. M. | PDF | N/A | BellaVista: Open-Source Visualization for Imaging-Based Spatial Transcriptomics | | Descriptron：测试人工智能以自动化分类学物种描述，附带用户友好软件包 | Van Dam, A. | PDF | N/A | Descriptron: Testing Artificial Intelligence for Automating Taxonomic Species Descriptions with a User-friendly Software Package | | 开发用于Nextclade的禽流感A(H5)病毒数据集，能够实现快速且准确的病毒分支分类。 | Ort, J. T. | PDF | N/A | Development of avian influenza A(H5) virus datasets for Nextclade enables rapid and accurate clade assignment | | 深度学习生成具有隐秘配体结合位点的apo RNA构象 | Kurisaki, I. | PDF | N/A | Deep learning generates apo RNA conformations with cryptic ligand binding site | | 使用rho、theta和phi描述蛋白质结构：以Caenopore-5为例的研究 | Li, W. | PDF | N/A | Protein Structure Description with rho, theta and phi: A Case Study with Caenopore-5 | | sCCIgen：用于细胞间相互作用研究的高保真空间分辨转录组数据模拟器。 | Song, X. | PDF | N/A | sCCIgen: A high-fidelity spatially resolved transcriptomics data simulator for cell-cell interaction studies. | | 有偏抽样混淆了机器学习对抗菌药物耐药性的预测 | Yu, Y. | PDF | N/A | Biased sampling confounds machine learning prediction of antimicrobial resistance | | 使用溶液和固态核磁共振对多药外排膜蛋白的主链和侧链进行1H、15N和13C共振归属 | Harding, B. D. | PDF | N/A | Backbone and Sidechain 1H, 15N and 13C Resonance Assignments of a Multidrug Efflux Membrane Protein using Solution and Solid-State NMR | | 当停止需要行动时；行动取消与取消行动取消之间的生理相似性 | Weber, S. | PDF | N/A | When Stopping Requires Going; Physiological Similarities Between Action Cancellation and the Cancellation of Action Cancellation | | VineColD：一个用于全球历史追踪和实时监测葡萄藤耐寒性的综合数据库 | Wang, H. | PDF | N/A | VineColD: an integrative database for global historical tracing and real-time monitoring of grapevine cold hardiness | | 基于模拟推理的过度兴奋性补偿 | Mueller-Komorowska, D. | PDF | N/A | Compensation of Hyperexcitability with Simulation-Based Inference | | 源自高度可扩展和再生性人类祖细胞的外泌体在缺血性中风大鼠模型中促进功能改善 | Lee, J. | PDF | N/A | Exosomes derived from highly scalable and regenerative human progenitor cells promote functional improvement in a rat model of ischemic stroke | | 通过在人工基质上局部增加碱度，可以提高早期珊瑚幼体的存活率。 | Ruszczyk, M. | PDF | N/A | Local alkalinity enhancement using artificial substrates increases survivorship of early-stage coral recruits | | 自然秀丽隐杆线虫（Caenorhabditis elegans）种群中的基因组结构变异 | Lesack, K. J. | PDF | N/A | Genome structural variation in natural Caenorhabditis elegans populations | | 以下是将这段英文翻译成中文的结果：

一个用于表征个体人类iPSC衍生伤害感受器轴突电生理学的体外平台

解释： - in vitro platform：体外平台，指的是在实验室环境中进行的实验，而不是在活体生物体内。 - characterizing：表征，指的是对某种特性进行详细描述和分析。 - axonal electrophysiology：轴突电生理学，研究轴突（神经细胞的输出部分）的电活动。 - individual human iPSC-derived nociceptors：个体人类iPSC衍生的伤害感受器，指的是从人类诱导多能干细胞（iPSC）分化而来的单个伤害感受器（负责感知疼痛的神经细胞）。

烟酰胺腺嘌呤二核苷酸（NAD+）缺乏引起的先天性疾病的斑马鱼模型

关于冠状病毒HKU5通过ACE2受体识别的跨物种传播的分子机制研究

翻译解释： - "Molecular Insights" 翻译为 "分子机制研究"，表示从分子层面深入探讨。 - "Cross-Species Spillover" 翻译为 "跨物种传播"，指病毒从一种物种传播到另一种物种的过程。 - "Coronavirus HKU5" 直接保留为 "冠状病毒HKU5"，因为这是特定病毒的名称。 - "via ACE2 Receptor Recognition" 翻译为 "通过ACE2受体识别"，表示病毒通过识别ACE2受体实现传播。

BioRxiv 2025-01-09 Papers

标题	作者	PDF链接	代码仓库	Title
进化在于细节：现代人类与尼安德特人的调控差异	Barker, H.	PDF	N/A	Evolution is in the details: Regulatory differences in modern human and Neanderthal
SATB1通过与碱基非配对区域（BURs）结合来组织基因组，为SATB1调控的基因表达提供了支架。	Kohwi, Y.	PDF	N/A	Genome organization by SATB1 binding to base-unpairing regions (BURs) provides scaffold for SATB1-regulated gene expression
陆禽性别二色性演化的大规模辐射研究：重新审视华莱士模型中偏向雌性的选择机制	Li, Z.	PDF	N/A	The evolution of sexual dichromatism in a large radiation of landfowl: Re-examining female-biased selection in Wallace's model
RAD51C在高尔基体和细胞核之间的时空动态调控同源重组和基因组稳定性。	Galea, G.	PDF	N/A	Spatiotemporal dynamics of RAD51C between the Golgi and nucleus regulates homologous recombination and genomic stability.
基于相互作用的神经群体的生物合理性决策模型	Baspinar, E.	PDF	N/A	A biologically plausible decision-making model based on interacting neural populations
通过数百万次实验室检测揭示的孕期和产后动态	Bar, A.	PDF	N/A	Pregnancy and postpartum dynamics revealed by millions of lab tests
以下是将这段英文翻译成中文的结果：

证据表明，合成的自体四倍体秀丽隐杆线虫（Caenorhabditis elegans）因多倍性而增强了抗逆性。

蛋白质序列的固有无序特征的概率注释

翻译说明： - "Probabilistic" 翻译为“概率的”，表示基于概率的预测或注释。 - "Annotations" 翻译为“注释”，指对序列特征的解释或标记。 - "Protein Sequences" 翻译为“蛋白质序列”，即蛋白质的氨基酸排列顺序。 - "Intrinsically Disordered Features" 翻译为“固有无序特征”，指蛋白质序列中缺乏固定三维结构的部分。

基于无标记多模态非线性光学成像的前列腺导管内癌的纹理分析分类

翻译说明： - "Texture-Analysis Classification" 翻译为 "纹理分析分类"，指的是通过分析图像纹理特征进行分类的方法。 - "Intraductal Carcinoma of the Prostate" 翻译为 "前列腺导管内癌"，是一种前列腺癌的亚型。 - "Label-Free" 翻译为 "无标记"，表示无需使用染色或标记物。 - "Multimodal Nonlinear Optical Imaging" 翻译为 "多模态非线性光学成像"，是一种结合多种非线性光学技术的成像方法。

老年参与者肌肉、活动能力和衰老研究中VO2峰值（最大摄氧量）的MicroRNA特征

翻译说明： - MicroRNA signatures：MicroRNA特征，指与特定生理状态或疾病相关的MicroRNA表达模式。 - VO2peak：最大摄氧量，是衡量心肺功能和有氧运动能力的重要指标。 - Study of Muscle, Mobility and Aging：肌肉、活动能力和衰老研究，是一项针对老年人的研究项目。

希望这个翻译对你有帮助！ | Karere, G. | PDF | N/A | MicroRNA signatures of VO2peak in older adult participants of the Study of Muscle, Mobility and Aging | | 进化稀疏学习与配对物种对比揭示了趋同性状的共享遗传基础 | Kumar, S. | PDF | N/A | Evolutionary sparse learning with paired species contrast reveals the shared genetic basis of convergent traits | | 人类蛋白质编码体细胞突变在不同组织和个体中的分布情况 | Xu, H. | PDF | N/A | Landscape of human protein-coding somatic mutations across tissues and individuals | | 分枝杆菌NDH-2与2-巯基喹唑啉酮抑制剂结合的结构 | Liang, Y. | PDF | N/A | Structure of mycobacterial NDH-2 bound to a 2-mercapto-quinazolinone inhibitor | | 多组学和生化重建揭示了CDK7依赖的机制，这些机制控制着RNA聚合酶II在基因5'端和3'端的功能。 | Luyties, O. | PDF | N/A | Multi-omics and biochemical reconstitution reveal CDK7-dependent mechanisms controlling RNA polymerase II function at gene 5'- and 3'-ends | | 以下是这段英文的中文翻译：

战略性地调节基于双分子转子荧光团的极性和粘度敏感性以用于α-突触核蛋白成像

脆性X综合征大鼠模型中头部方向信号的年龄依赖性变化

翻译解释： - Age-dependent：年龄依赖性的，表示与年龄相关的。 - alterations：变化，指在某个方面的改变。 - head-direction signal：头部方向信号，通常指动物在空间导航中头部朝向的信号。 - rat model：大鼠模型，指用大鼠作为研究对象建立的实验模型。 - Fragile X Syndrome：脆性X综合征，一种遗传性智力障碍疾病。

整句话的意思是：在脆性X综合征的大鼠模型中，头部方向信号会随着年龄的增长而发生改变。 | Moore, N. | PDF | N/A | Age-dependent alterations in the head-direction signal in a rat model of Fragile X Syndrome | | 揭示失忆小鼠中的隐藏知识 | Santi, A. | PDF | N/A | Revealing hidden knowledge in amnestic mice | | 调节细胞衰老可调控整合应激反应信号以控制血细胞稳态 | Ghosh, K. | PDF | N/A | Modulation of cellular ageing regulates Integrated Stress Response signalling to control blood cell homeostasis | | 在早期蛹发育过程中，组织生长模式的转换延长了果蝇翅原基的生长阶段。 | El Marzkioui, K. | PDF | N/A | A switch in the mode of tissue growth extends the growth phase of Drosophila wing primordia during early pupal development | | microRNA-210通过靶向线粒体自噬增强细胞存活和旁分泌潜能，用于心脏细胞治疗。 | Alonaizan, R. | PDF | N/A | microRNA-210 enhances cell survival and paracrine potential for cardiac cell therapy while targeting mitophagy. | | 胎儿的造血祖细胞具有独特的起源和命运 | Soares-da-Silva, F. | PDF | N/A | Distinct origin and fate for fetal hematopoietic progenitors | | 保守的核形态识别功能性放射状胶质神经祖细胞 | Soriano, J. P. | PDF | N/A | CONSERVED NUCLEAR MORPHOLOGY IDENTIFIES FUNCTIONAL RADIAL GLIA NEURAL PROGENITORS | | 在发育中的果蝇眼睛和翅膀中敲除PR-DUB亚单位calypso会导致组织模式异常，大小和形状发生改变。 | Luf, M. | PDF | N/A | Knockdown of PR-DUB subunit calypso in the developing Drosophila eye and wing results in mis-patterned tissues with altered size and shape | | 肠道RICT-1通过卵黄蛋白VIT-3调控秀丽隐杆线虫幼虫生殖细胞前体库 | Kloock, A. | PDF | N/A | Intestinal RICT-1 regulates the larval germline progenitor pool via the vitellogenin VIT-3 in C. elegans | | Foxi2和Sox3是控制外胚层胚层分化的主要调控因子。 | Hendrickson, C. | PDF | N/A | Foxi2 and Sox3 are master regulators controlling ectoderm germ layer specification | | 利用谱系追踪和单细胞转录组学解析斑马鱼肝胆管的异质性和细胞可塑性 | Mi, J. | PDF | N/A | Deciphering the zebrafish hepatic duct heterogeneity and cell plasticity using lineage tracing and single-cell transcriptomics | | 在斑马鱼生长突增期间，胆管细胞在部分肝脏损伤后对肝细胞的再生起到了贡献作用。 | Eski, S. E. | PDF | N/A | Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish | | 血清素抑制雌性慈鲷鱼的性接受能力 | Lee, P. | PDF | N/A | Serotonin inhibits sexual receptivity in female cichlid fish | | 金丝雀在繁殖季节过渡期间对独唱和重叠歌唱的调节方式有所不同 | Totiger, S. | PDF | N/A | Canaries differentially modulate solo and overlapping singing during the transition to the breeding season | | 婴儿习惯化的理性信息收集解释 | Karni, G. | PDF | N/A | A Rational Information Gathering Account of Infant Habituation | | JNK通路抑制导致ER+乳腺癌对联合内分泌治疗和CDK4/6抑制的耐药性 | Alexandrou, S. | PDF | N/A | JNK pathway suppression drives resistance to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer | | 上下文依赖性翻译抑制作为一种新型肿瘤治疗模式 | Diamond, P. D. | PDF | N/A | Context-dependent translation inhibition as a novel oncology therapeutic modality | | 一项整合了单细胞和空间转录组学的甲状腺癌进展图谱研究，识别出了具有预后意义的成纤维细胞亚群。 | Loberg, M. A. | PDF | N/A | An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations | | 氧化磷酸化受损驱动原发性肿瘤逃逸和转移 | Arner, E. N. | PDF | N/A | Impaired oxidative phosphorylation drives primary tumor escape and metastasis | | 上游开放阅读框翻译增强了有丝分裂停滞癌细胞中免疫原性肽的呈递 | Kowar, A. | PDF | N/A | Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells | | APMAT分析揭示了CD8 T细胞受体、同源抗原以及T细胞表型和持久性之间的关联。 | Xie, J. | PDF | N/A | APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence | | 与COVID-19严重程度相关的DPP9基因调控变异的鉴定与功能表征 | Farah, G. | PDF | N/A | Identification and Functional Characterization of Regulatory Variants in DPP9 Associated with COVID-19 Severity | | 设计新型合成启动子以调节T细胞中的基因表达 | Bonfa, G. | PDF | N/A | Design of novel synthetic promoters to tune gene expression in T cells | | 在二十面体病毒解组装过程中基因组RNA的有序释放 | Zhou, Y. | PDF | N/A | Ordered release of genomic RNA during icosahedral virus disassembly | | 重新审视多西环素暴露后预防（doxy-PEP）对奈瑟菌共生菌中多西环素耐药性选择的潜在影响 | Robinson, L. R. | PDF | N/A | Re-visiting the potential impact of doxycycline post-exposure prophylaxis (doxy-PEP) on the selection of doxycycline resistance in Neisseria commensals | | 宏转录组学揭示了珊瑚Porites lutea中“谁在做什么”的情况。 | Tandon, K. | PDF | N/A | Metatranscriptomics sheds light on 'who is doing what' in the coral Porites lutea | | 膳食蛋白质来源通过直接影响以及与肠道微生物群的相互作用，改变了蛋白酶、肠上皮和免疫蛋白的丰度。 | Awan, A. | PDF | N/A | Source of dietary protein alters the abundance of proteases, intestinal epithelial and immune proteins both directly and via interactions with the gut microbiota | | UFMylation促进正黄病毒属感染性颗粒的产生 | Schmidt, H. M. | PDF | N/A | UFMylation promotes orthoflavivirus infectious particle production | | 环指E3连接酶RNF25独立于其在泛素信号传导中的典型作用保护DNA复制叉 | Chiou, L. F. | PDF | N/A | The RING Finger E3 Ligase RNF25 Protects DNA Replication Forks Independently of its Canonical Roles in Ubiquitin Signaling | | METTL3通过促进m6A-YTHDC1依赖的SGK1基因转录加剧内膜增生 | huang, J. | PDF | N/A | METTL3 Aggravates Intimal Hyperplasia by Facilitating the m6A-YTHDC1-dependent SGK1 Gene Transcription | | 核仁应激诱导化合物影响RNA聚合酶I转录机制对rDNA的占据 | Yglesias, M. V. | PDF | N/A | Nucleolar Stress-inducing Compounds Influence rDNA occupancy of RNA Polymerase I Transcription Machinery | | SLFN11介导的tRNA调控通过破坏蛋白质稳态来诱导细胞死亡，以响应DNA损伤剂。 | Iimori, Y. | PDF | N/A | SLFN11-mediated tRNA regulation induces cell death by disrupting proteostasis in response to DNA-damaging agents | | 严格的肠道来源细胞外囊泡分离流程及其对潜伏HIV的影响 | Anyanwu, N. C. J. | PDF | N/A | Rigorous process for isolation of gut-derived extracellular vesicles and the effect on latent HIV | | 通过结构分析揭示了海洋假交替单胞菌中完整的{λ}-卡拉胶降解级联反应。 | Vickers, C. J. | PDF | N/A | The complete {lambda}-carrageenan depolymerization cascade from a marine Pseudoalteromonad revealed by structural analysis of the enzymes. | | AMPylation调节PLD3的加工过程。 | Hoffmann, L. | PDF | N/A | AMPylation regulates PLD3 processing. | | 整合素α5靶向抗体的结构和功能表征用于抗血管生成治疗 | Nguyen, A. | PDF | N/A | Structural and functional characterization of integrin a5-targeting antibodies for anti-angiogenic therapy | | Ag+调控的凝血酶适配体 | Alieva, R. | PDF | N/A | Ag+-regulated aptamers to thrombin | | 前导链和滞后链上的脱碱基位点对脊椎动物复制体的进程有不同的影响，但涉及类似的旁路机制。 | Cranford, M. T. | PDF | N/A | Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms | | 以下是这段文字的中文翻译：

结构洞察白色念珠菌锌载体Pra1的锌清除机制

BioRxiv 2025-01-08 Papers

标题	作者	PDF链接	代码仓库	Title
microRNA-19b调控鸟类前脑的增殖与模式形成	Mishra, A.	PDF	N/A	microRNA-19b regulates proliferation & patterning in the avian forebrain
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从体内脉冲序列重建电路连接性：基于深度域自适应匹配的方法	Sheng, K.	PDF	N/A	Reconstructing Circuit Connectivity from in vivo Spike Trains Using Deep Domain-Adaptive Matching
mimicINT：一种用于推断微生物-宿主蛋白质相互作用的工作流程	Choteau, S. A.	PDF	N/A	mimicINT: a workflow for microbe-host protein interaction inference
经验回放促进了网格细胞多尺度六边形模式的快速形成。	Zhang, B.	PDF	N/A	Experience replay facilitates the rapid formation of multi-scale hexagonal patterns of grid cells
使用人类诱导多能干细胞（iPSC）群体筛选药物反应的变异性	Platani, M.	PDF	N/A	Screening for variable drug responses using human iPSC cohorts
除了毒牙之外：Uloboridae蜘蛛虽然失去了毒液，但并未失去其毒性。	Peng, X.	PDF	N/A	Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity
电影揭示了婴儿视觉皮层的精细组织结构。	Ellis, C. T.	PDF	N/A	Movies reveal the fine-grained organization of infant visual cortex
工程细菌启动并控制一种溶瘤病毒	Singer, Z. S.	PDF	N/A	Engineered bacteria launch and control an oncolytic virus
撤回：HER2细胞定位、细胞间接触和细胞密度调节HER2阳性乳腺癌中的癌细胞可塑性	Sameri, S.	PDF	N/A	WITHDRAWN: HER2 Cellular Localization, Cell-Cell Contacts, and Cell Density Regulate Cancer Cell Plasticity in HER2+ Breast Cancer
小鼠梨状皮层和内嗅皮层中气味与位置信息的差异编码	Mena, W.	PDF	N/A	Differential encoding of odor and place in mouse piriform and entorhinal cortex
皮层感觉老化具有层次特异性	Liu, P.	PDF	N/A	Cortical sensory aging is layer-specific
本地树木覆盖率预测热带乡村景观中蚊子物种丰富度和疾病媒介的存在	Farner, J. E.	PDF	N/A	Local tree cover predicts mosquito species richness and disease vector presence in a tropical countryside landscape
脑类器官中的原序列模拟了内在脑状态	van der Molen, T.	PDF	N/A	Protosequences in brain organoids model intrinsic brain states
物种界定分析表明，来自地中海东北部沿海地区的Terpios gelatinosus（海绵动物门，普通海绵纲）存在隐存种现象。	Ozturk, E.	PDF	N/A	Species delimitation analysis indicates cryptic speciation for Terpios gelatinosus (Porifera, Demospongiae) from coastal regions of the northeastern Mediterranean Sea
MagIC-Cryo-EM: 在磁性珠粒上对异质样品中稀缺大分子进行结构测定	Arimura, Y.	PDF	N/A	MagIC-Cryo-EM: Structural determination on magnetic beads for scarce macromolecules in heterogeneous samples
将圆形变为方形或结合条纹：真核生物中棋盘图案的多样性与形成	Galipot, P.	PDF	N/A	Changing rounds into squares or combining stripes: Diversity and formation of checkerboard patterns in Eukaryotes
通过深度学习探索从头设计的双功能抗菌肽库	Dong, R.	PDF	N/A	Exploring the repository of de novo designed bifunctional antimicrobial peptides through deep learning
CapP介导了机会性人类病原体蜡样芽孢杆菌（Bacillus cereus）中生物膜特异性菌毛的结构形成。	Alvarez-Mena, A.	PDF	N/A	CapP mediates the structural formation of biofilm-specific pili in the opportunistic human pathogen Bacillus cereus
爱丁堡大学生物科学家开放数据实践的兴起	Deeb, H.	PDF	N/A	The Rise of Open Data Practices Among Bioscientists at the University of Edinburgh
ATG6与NPR1相互作用通过增加其核积累和稳定性，增强了拟南芥对Pst DC3000/avrRps4的抗性。	Zhang, B.	PDF	N/A	ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability
NFIB影响小鼠GABA能神经元成熟过程中祖细胞的能力	Bright, A. R.	PDF	N/A	NFIB influences progenitor competence in maturation of GABAergic neurons in mice
循环中的线粒体生物能量学作为肝脏生物能量学的指纹：如何监测遗传性MASLD	Paolini, E.	PDF	N/A	Circulating mitochondrial bioenergetics as fingerprint of the hepatic one: how to monitor genetic MASLD
大流行性大肠杆菌克隆的基本繁殖数差异显著，且可与大流行性流感病毒相媲美。	Ojala, F. A.	PDF	N/A	Basic reproduction number for pandemic Escherichia coli clones varies markedly and can be comparable to pandemic influenza viruses
钙膜蛋白/C16orf74中的一个新基序决定了钙调磷酸酶介导的多聚体去磷酸化作用。	Bradburn, D. A.	PDF	N/A	A novel motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin
Peptonizer2000：为宏蛋白质组学带来信心	Holstein, T.	PDF	N/A	The Peptonizer2000: bringing confidence to metaproteomics
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磷酸二酯酶1A与YTHDF2发生物理相互作用，并加强非小细胞肺癌的进展。	Zhang, C.	PDF	N/A	Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer
大分子凝聚不太可能缓冲细胞内渗透压。	Kay, A. R.	PDF	N/A	Macromolecular condensation is unlikely to buffer intracellular osmolality
蛋白激酶A调控的中心体肌动蛋白池设定了T细胞极化的阈值。	Randriamampita, C.	PDF	N/A	A protein kinase A-regulated centrosomal actin pool sets the threshold for T cell polarization
无细胞表达和SMA共聚物封装功能性受体酪氨酸激酶疾病变体FGFR3-TACC3	Snow, A. J. D.	PDF	N/A	Cell-free expression and SMA copolymer encapsulation of a functional receptor tyrosine kinase disease variant, FGFR3-TACC3
一种可复制且可推广的基于神经影像学的个体疼痛敏感性指标	Zhang, L.-B.	PDF	N/A	A replicable and generalizable neuroimaging-based indicator of pain sensitivity across individuals
巴罗萨谷地区葡萄园蒸散发组分、作物系数及水分生产力的区域动态变化	Phogat, V.	PDF	N/A	Regional dynamics in the evapotranspiration components, crop coefficients and water productivity of vineyards in the Barossa Valley
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蛋白质稳态调节抗生素耐药细菌中的基因剂量进化	Jena, C.	PDF	N/A	Proteostasis modulates gene dosage evolution in antibiotic-resistant bacteria
ComBat-met：调整DNA甲基化数据中的批次效应	Wang, J.	PDF	N/A	ComBat-met: Adjusting Batch Effects in DNA Methylation Data
单分子脂质生物传感器减轻内源性效应蛋白的抑制	Holmes, V.	PDF	N/A	Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins
Colora：一个用于完整染色体级别从头基因组组装的Snakemake工作流程	Obinu, L.	PDF	N/A	Colora: A Snakemake Workflow for Complete Chromosome-scale De Novo Genome Assembly
Maf家族bZIP转录因子NRL在视网膜光感受器中与RNA结合蛋白和R环相互作用	Corso Diaz, X.	PDF	N/A	Maf-family bZIP transcription factor NRL interacts with RNA-binding proteins and R-loops in retinal photoreceptors
基于生物学信息的皮质模型预测光遗传学扰动	Sourmpis, C.	PDF	N/A	Biologically informed cortical models predict optogenetic perturbations
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撤回：遮荫对加勒比海柳珊瑚（Briareum asbestinum）行为生态学的影响，研究地点为美国佛罗里达群岛	Draud, S. L.	PDF	N/A	WITHDRAWN: Influence of Shading on the Behavioral Ecology of a Caribbean Alcyonacean Octocoral, Briareum asbestinum, in the Florida Keys, United States
以下是这段文字的中文翻译：

计算视角下C肽流动性驱动的小型前胰岛素变构行为研究

本研究聚焦于睾丸酮丛毛单胞菌TA441在类固醇降解过程中，对C17位丙酰基残基的去除机制。研究团队通过系统性的实验与分析，成功鉴定出参与该生物转化过程的关键酶类，包括脱氢酶、水合酶和醛缩酶。这些酶在类固醇分子侧链的修饰与断裂中扮演着不可或缺的角色，确保了降解途径的高效进行。

研究进一步深入探讨了这些酶在空间结构上的组织方式及其功能协同机制。特别是，研究揭示了两种重要的酶复合物：(ChsE1-ChsE2)2和(ChsH1-ChsH2MaoC)2-(Ltp2-ChsH2DUF35)2。这些复合物通过特定的蛋白质-蛋白质相互作用形成稳定的多酶组装体，不仅优化了底物的传递与转化效率，还可能通过变构效应调节各组成酶的活性，以适应不同的代谢需求。

结构洞察癫痫相关配体-受体复合物LGI1-ADAM22的异源六聚体组装

翻译说明：
- "Structural insights" 翻译为“结构洞察”，表示对结构的深入理解。
- "heterohexameric assembly" 指由不同亚基组成的六聚体结构，翻译为“异源六聚体组装”。
- "epilepsy-related" 表示与癫痫相关，翻译为“癫痫相关的”。
- "ligand-receptor complex" 指配体与受体形成的复合物，翻译为“配体-受体复合物”。
- "LGI1-ADAM22" 是具体的蛋白质名称，保留原文不翻译。

单分子分析PARP1与G-四链体的相互作用

针对结核分枝杆菌β-内酰胺酶BlaC的天然化合物的分子对接、验证、动态模拟和药代动力学预测

翻译说明： - Molecular docking：分子对接 - validation：验证 - dynamic simulation：动态模拟 - pharmacokinetic prediction：药代动力学预测 - natural compounds：天然化合物 - Mycobacterium tuberculosis：结核分枝杆菌 - Beta-lactamase BlaC：β-内酰胺酶BlaC

人类T细胞受体对恶性疟原虫环子孢子蛋白（CSP）的克隆性、特异性及HLA限制性

翻译说明： - Clonality：克隆性，指T细胞受体的克隆扩增特性。 - specificity：特异性，指T细胞受体对特定抗原的识别能力。 - HLA restriction：HLA限制性，指T细胞受体识别抗原时需要与特定的人类白细胞抗原（HLA）分子结合。 - Plasmodium falciparum CSP：恶性疟原虫环子孢子蛋白（CSP），是疟疾疫苗研究中的重要抗原。

“原神经基因Neurog1和Neurog2在发育中的背根神经节中的功能等效性突出了神经发生时间对偏向体感前体命运的重要性。”

翻译说明： - Functional Equivalence：功能等效性，指两个基因在功能上具有相似或相同的作用。 - Proneural Genes：原神经基因，参与神经发育的基因。 - Neurog1 and Neurog2：两个具体的原神经基因名称。 - Developing Dorsal Root Ganglia：发育中的背根神经节，是感觉神经元的聚集区域。 - Timing of Neurogenesis：神经发生的时间，指神经元生成的时间点。 - Biasing Somatosensory Precursor Fates：偏向体感前体命运，指影响体感神经元前体细胞的发育方向。

整句话强调了Neurog1和Neurog2在背根神经节发育中的功能相似性，并指出神经发生的时间点对体感神经元前体细胞的命运决定具有重要影响。 | Desiderio, S. | PDF | N/A | Functional Equivalence of the Proneural Genes Neurog1 and Neurog2 in the Developing Dorsal Root Ganglia Highlights the Importance of Timing of Neurogenesis in Biasing Somatosensory Precursor Fates | | 谱系启动和细胞类型比例分配依赖于随机因素和确定性因素之间的相互作用。 | Salvidge, W. | PDF | N/A | Linage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors | | Dmrt2在胚胎扣带皮层中调控神经元发育：揭示性别偏向的脆弱性

BioRxiv 2025-01-07 Papers

标题	作者	PDF链接	代码仓库	Title
改变的亨廷顿蛋白-染色质相互作用预测亨廷顿病小鼠模型中的转录和表观遗传变化	Pearl, J. R.	PDF	N/A	Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntington's Disease Mouse Models
从分类学归属估计共识蛋白质组和代谢功能	Belcour, A.	PDF	N/A	Estimating consensus proteomes and metabolic functions from taxonomic affiliations
MAIT细胞对胶质母细胞瘤有负面影响。	keretsu, S.	PDF	N/A	MAIT cells have a negative impact on glioblastoma
在小鼠进行嗅觉引导行为期间，基底前脑中PV和SST GABA能神经元活动的不同模式	Moss, E. H.	PDF	N/A	Distinct patterns of PV and SST GABAergic neuronal activity in the basal forebrain during olfactory-guided behavior in mice
ARHGEF18是一种响应血流的交换因子，控制着内皮细胞的紧密连接和血管渗漏。	Batta, S. P. R.	PDF	N/A	ARHGEF18 is a flow-responding exchange factor controlling endothelial tight junctions and vascular leakage
果蝇表皮细胞本质上是机械敏感的，并能调节伤害性行为输出。	Yoshino, J.	PDF	N/A	Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs
PI(3,5)P2 控制 I 类 PI3K 的信号传导活性	Sun, J.	PDF	N/A	PI(3,5)P2 Controls the Signaling Activity of Class I PI3K
BiGPICC：一种基于图的方法，用于从突变数据中识别致癌基因组合	Oles, V.	PDF	N/A	BiGPICC: a graph-based approach to identifying carcinogenic gene combinations from mutation data
内在无序蛋白的构象熵阻止外来分子进入生物分子凝聚体	Grigorev, V.	PDF	N/A	Conformational entropy of intrinsically disordered proteins bars intruders from biomolecular condensates
基于图像的微核细胞识别与分离以解析细胞后果	DiPeso, L.	PDF	N/A	Image-based identification and isolation of micronucleated cells to dissect cellular consequences
脂质转移蛋白和一种PI 4-激酶启动核内磷酸肌醇信号传导。	Carrillo, N. D.	PDF	N/A	Lipid transfer proteins and a PI 4-kinase initiate nuclear phosphoinositide signaling
牛（Bos taurus）热应激反应的全基因组关联研究	Czech, B.	PDF	N/A	Genome-wide association study of heat stress response in Bos taurus
在小鼠自然攀爬过程中，选择性直接运动皮层的影响	Koh, N.	PDF	N/A	Selective direct motor cortical influence during naturalistic climbing in mice
衰老影响肺损伤后小鼠肺毛细血管内皮细胞的重编程	Truchi, M.	PDF	N/A	Aging affects reprogramming of murine pulmonary capillary endothelial cells after lung injury
基于抗体系统的靶向蛋白质编辑	Rimon, O.	PDF	N/A	Targeted protein editing with an antibody-based system
使用组合通道复用和深度学习进行高维成像的升级	Ben-Uri, R.	PDF	N/A	Escalating High-dimensional Imaging using Combinatorial Channel Multiplexing and Deep Learning
肝窦内皮细胞构成了血红蛋白清除的主要途径。	Zurawska, G.	PDF	N/A	Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance
NF1调节微管修复及对抗体-药物偶联物的敏感性	Achutti Duso, B.	PDF	N/A	NF1 modulates microtubule repair and sensitivity to antibody-drug conjugates
创伤性脑损伤后海马颗粒细胞的双相变化	Danielewicz, J.	PDF	N/A	Biphasic Changes in Hippocampal Granule Cells after Traumatic Brain Injury
系统性发现与人类绝缘子位点相关的定向调控基序	Osato, N.	PDF	N/A	Systematic discovery of directional regulatory motifs associated with human insulator sites
西欧亚的草原血统与日耳曼语言的传播	McColl, H.	PDF	N/A	Steppe Ancestry in western Eurasia and the spread of the Germanic Languages
胚胎期II型神经母细胞谱系在大小和数量上的差异与甲虫和苍蝇之间中央复合体发育时间的差异相关	Rethemeier, S.	PDF	N/A	Differences in size and number of embryonic type-II neuroblast lineages correlate with divergent timing of central complex development between beetle and fly
HIF2α抑制线粒体中谷氨酰胺酶的聚集，以维持透明细胞肾细胞癌的生长	Zhao, W.	PDF	N/A	HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell Renal Cell Carcinoma
使用信息性先验来解决具有识别错误的占用模型中的可识别性问题	Monchy, C.	PDF	N/A	Using informative priors to account for identifiability issues in occupancy models with identification errors
免疫挑战下的Disc1+/-小鼠出现发育性嗅觉功能障碍和异常气味记忆	Parbst, F.	PDF	N/A	Developmental olfactory dysfunction and abnormal odor memory in immune-challenged Disc1+/- mice
健康老年人中循环血小板直接控制神经血管功能的证据	Rossetti, G. M. K.	PDF	N/A	Evidence for direct control of neurovascular function by circulating platelets in healthy older adults
以下是这段英文的中文翻译：

通过水平基因转移从植物中获得的功能性碳水化合物活性酶在烟粉虱（Bemisia tabaci）中的作用

翻译说明： - Functional carbohydrate-active enzymes：功能性碳水化合物活性酶 - acquired by horizontal gene transfer：通过水平基因转移获得 - from plants：从植物中 - in the whitefly Bemisia tabaci：在烟粉虱（Bemisia tabaci）中

希望这个翻译对你有帮助！ | Colinet, D. | PDF | N/A | Functional carbohydrate-active enzymes acquired by horizontal gene transfer from plants in the whitefly Bemisia tabaci | | 在大样本中的同源片段 | Temple, S. D. | PDF | N/A | Identity-by-descent segments in large samples | | 通过一次性基因编辑App C端在体内长期拯救阿尔茨海默病缺陷。 | Aulston, B. | PDF | N/A | Long term rescue of Alzheimer deficits in vivo by one-time gene-editing of App C-terminus. | | 阿尔茨海默病基因SORL1调控人类小胶质细胞中溶酶体的功能 | Mishra, S. | PDF | N/A | The Alzheimer's disease gene SORL1 regulates lysosome function in human microglia | | 多组学与深度表型整合分析为马铃薯对多重非生物胁迫的响应提供了新的见解 | Zagorscak, M. | PDF | N/A | Integration of multi-omics and deep phenotyping provides novel insights into multiple abiotic stress responses in potato | | 在行为神经科学实验中评估成功率时，在保持小样本量的同时提高统计功效 | Theo, D. | PDF | N/A | Enhancing Statistical Power While Maintaining Small Sample Sizes in Behavioral Neuroscience Experiments Evaluating Success Rates | | 迈向基于自然语言的全新蛋白质设计 | Dai, F. | PDF | N/A | Toward De Novo Protein Design from Natural Language | | 在大鼠内侧颞叶中感觉和恐惧记忆的整合 | Wong, F. S. | PDF | N/A | Integration of sensory and fear memories in the rat medial temporal lobe | | 使用扩展平铺光片显微镜对无性涡虫神经元异速生长和神经肌肉投射的3D重建 | Lu, J. | PDF | N/A | 3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy | | 使用扩展平铺光片显微镜对无性生殖涡虫的神经元异速生长和神经肌肉投射进行三维重建 | Lu, J. | PDF | N/A | 3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy | | ORMDL3通过促进RIG-I的降解来抑制I型干扰素信号传导和抗肿瘤免疫。 | zeng, q. | PDF | N/A | ORMDL3 restrains type-I interferon signaling and anti-tumor immunity by promoting RIG-I degradation | | 通过适应性实验揭示的真菌交配型染色体中的庇护负载 | Guyot, L. | PDF | N/A | Sheltered load in fungal mating-type chromosomes revealed by fitness experiments | | 强选择但低重复性：温度特异性对基因组预测适应性的影响 | Rego, A. | PDF | N/A | Strong Selection, but low repeatability: Temperature-specific effects on genomic predictions of adaptation | | 以下是这段英文的中文翻译：

丙戊酸对髓母细胞瘤神经球干性和分化调节因子的调控

翻译说明： - "Modulation" 译为“调控” - "Stemness" 译为“干性”（指干细胞的特性） - "Differentiation Regulators" 译为“分化调节因子” - "Valproic Acid" 译为“丙戊酸” - "Medulloblastoma" 译为“髓母细胞瘤” - "Neurospheres" 译为“神经球”

一个计算设计的多样化且具有选择性的过氧化酶面板，用于萜烯的氧官能化。

翻译解释： - "computationally designed" 翻译为“计算设计的”，表示通过计算方法进行设计。 - "panel" 翻译为“面板”或“一组”，在这里指的是一个集合或系列。 - "diverse and selective" 翻译为“多样化且具有选择性的”，描述了这些过氧化酶的特性。 - "peroxygenases" 翻译为“过氧化酶”，是一种酶类。 - "terpene oxyfunctionalization" 翻译为“萜烯的氧官能化”，指的是在萜烯分子中引入氧原子的化学反应。

整体翻译保持了原文的科学性和准确性，同时使中文表达流畅易懂。 | Munch, J. | PDF | N/A | A computationally designed panel of diverse and selective peroxygenases for terpene oxyfunctionalization | | UBR-1 缺陷导致秀丽隐杆线虫对伊维菌素产生抗性。 | Li, Y. | PDF | N/A | UBR-1 deficiency leads to ivermectin resistance in C. elegans | | 人类腹侧颞叶皮层功能偏侧化的个体差异：局部竞争与长程耦合 | Blauch, N. M. | PDF | N/A | Individual variation in the functional lateralization of human ventral temporal cortex: Local competition and long-range coupling | | 探索基因组编辑信息的管道，利用大型语言模型和基因组编辑元数据库 | Suzuki, T. | PDF | N/A | Pipeline to explore information on genome editing using large language models and genome editing meta-database | | BrainACTIV：利用基于扩散的图像处理技术识别驱动皮层选择性的视觉语义属性 | Garcia Cerdas, D. | PDF | N/A | BrainACTIV: Identifying visuo-semantic properties driving cortical selectivity using diffusion-based image manipulation | | 通过多重邻近标记进行染色质结构映射 | Delamarre, A. | PDF | N/A | Chromatin architecture mapping by multiplex proximity tagging | | 哺乳动物大脑发育与进化中的双重计算系统 | Imam, N. | PDF | N/A | Dual Computational Systems in the Development and Evolution of Mammalian Brains | | Rac1抑制可预防转甲状腺素蛋白淀粉样多发性神经病中的轴突细胞骨架功能障碍 | Magalhaes, J. | PDF | N/A | Rac1 inhibition prevents axonal cytoskeleton dysfunction in Transthyretin Amyloid Polyneuropathy | | 在体内通过光调节激酶对内源性标记蛋白的调控 | vigano, a. m. | PDF | N/A | In vivo regulation of an endogenously-tagged protein by a light-regulated kinase | | 高分辨率成像与三维RPE（视网膜色素上皮）片层结构的解析 | Donaldson, K. J. | PDF | N/A | High resolution imaging and interpretation of three-dimensional RPE sheet structure | | 快速模拟同源片段 | Temple, S. D. | PDF | N/A | Fast simulation of identity-by-descent segments | | 利用全基因组、线粒体DNA和单倍型块来解析复杂的人口历史：以广泛混合的北极鱼类为例 | Dallaire, X. | PDF | N/A | Leveraging whole genomes, mitochondrial DNA, and haploblocks to decipher complex demographic histories: an example from a broadly admixed arctic fish | | 秀丽隐杆线虫早期胚胎中新蛋白质翻译的景观与调控 | Shukla, Y. | PDF | N/A | Landscape and regulation of new protein translation in the early C. elegans embryo | | ABHD2活性对于孕酮对人类精子的非基因组作用不是必需的。 | Arnolds, O. | PDF | N/A | ABHD2 activity is not required for the non-genomic action of progesterone on human sperm | | 早期抗生素和益生菌治疗对极低出生体重早产儿肠道微生物组和耐药组的影响 | Kiu, R. | PDF | N/A | Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants | | 一种用于预测蛋白质内在无序区域相互作用的深度学习方法 | Majila, K. | PDF | N/A | A deep learning method for predicting interactions for intrinsically disordered regions of proteins | | HapCNV：低输入DNA测序数据中CNV检测的综合框架 | Yu, X. | PDF | N/A | HapCNV: A Comprehensive Framework for CNV Detection in Low-input DNA Sequencing Data | | 为细胞基因扰动的计算机模拟基准测试人工智能模型 | Li, C. | PDF | N/A | Benchmarking AI Models for In Silico Gene Perturbation of Cells | | 在实验室中展示软X射线断层扫描技术，用于结合X射线和光学显微镜的低温生物成像研究。 | O'Connor, S. | PDF | N/A | Demonstrating Soft X-Ray Tomography in the lab for correlative cryogenic biological imaging using X-rays and light microscopy | | 以下是这段文字的中文翻译：

在裸鳃类动物Caloria militaris中，对钵水母类水螅体的捕食及选择性刺丝囊的摄取动态

翻译解释： - Predation on scyphozoan polyps：对钵水母类水螅体的捕食。钵水母类（Scyphozoa）是水母的一个类群，水螅体是其生活史中的一个阶段。 - selective nematocyst incorporation dynamics：选择性刺丝囊的摄取动态。刺丝囊（nematocyst）是刺胞动物（如水母）特有的细胞器，用于捕食和防御。 - aeolid：裸鳃类动物，是一类海蛞蝓。 - Caloria militaris：一种裸鳃类动物的学名。

希望这个翻译对你有帮助！ | Dror, H. | PDF | N/A | Predation on scyphozoan polyps and selective nematocyst incorporation dynamics in the aeolid, Caloria militaris | | 病毒准种推断：个体样本比较分析方法 | Gregori, J. | PDF | N/A | Inference with Viral Quasispecies. Methods for Individual Samples Comparative Analysis. | | 状态依赖性对棘状投射神经元的调节控制帕金森病小鼠模型中左旋多巴诱导的运动障碍 | Zhai, S. | PDF | N/A | State-dependent modulation of spiny projection neurons controls levodopa-induced dyskinesia in a mouse model of Parkinson's disease | | 使用实验和模型评估浮游植物-细菌相互作用的四种潜在机制 | Weissberg, O. | PDF | N/A | Four Potential Mechanisms Underlying Phytoplankton-Bacteria Interactions Assessed Using Experiments and Models | | 一种改进的快速且灵敏的长片段扩增方法，用于基于纳米孔技术的呼吸道合胞病毒（RSV）全基因组测序 | Dong, X. | PDF | N/A | An improved rapid and sensitive long amplicon method for nanopore-based RSV whole genome sequencing | | 应对不确定性：奖励位置的变化引发海马体空间表征的重组 | Tessereau, C. | PDF | N/A | Navigating uncertainty: reward location variability induces reorganization of hippocampal spatial representations | | 基因组缺失和重复对人类大脑皮层认知能力的镜像效应 | Kumar, K. | PDF | N/A | Mirror effect of genomic deletions and duplications on cognitive ability across the human cerebral cortex | | 杏仁核GABA神经元：压力与繁殖的守门人 | Yu, J. | PDF | N/A | Amygdala GABA Neurons: Gatekeepers of Stress and Reproduction | | 麻醉成年雄性大鼠蓝斑去甲肾上腺素能神经元的昼夜节律调制 | Rae, R. J. | PDF | N/A | Diurnal Modulation of Locus Coeruleus Noradrenergic Neurons in Anesthetized Adult Male Rats | | 转录对持续氧化应激的反应需要G蛋白偶联受体信号通路的胆碱能激活 | Biswas, K. | PDF | N/A | Transcriptional responses to prolonged oxidative stress require cholinergic activation of G-protein-coupled receptor signaling | | 内源性大麻素通过逆向增益控制促进短暂的奖赏参与。 | Marcus, D. J. | PDF | N/A | Endocannabinoids facilitate transitory reward engagement through retrograde gain control | | 基于注意力机制的条件去噪扩散概率模型用于特定个体脑网络合成 | Ajith, M. | PDF | N/A | Conditional Denoising Diffusion Probabilistic Models with Attention for Subject-Specific Brain Network Synthesis | | WormID-Benchmark：在神经元分辨率下提取秀丽隐杆线虫的全脑神经动力学 | Adhinarta, J. | PDF | N/A | WormID-Benchmark: Extracting Whole-Brain Neural Dynamics of C. elegans At the Neuron Resolution | | WormID-基准测试：以神经元分辨率提取秀丽隐杆线虫的全脑神经动力学 | Adhinarta, J. | PDF | N/A | WormID-Benchmark: Extracting Whole-Brain Neural Dynamics of C. elegans At the Neuron Resolution | | 背侧海马体介导小鼠的光-音感觉预条件化任务 | Pinho, J. S. | PDF | N/A | Dorsal hippocampus mediates light-tone sensory preconditioning task in mice | | VIP中间神经元驱动的抑制性回路中的NMDA依赖性共塑性 | Jablonska, J. | PDF | N/A | NMDA-dependent coplasticity in VIP interneuron-driven inhibitory circuits | | 非常规短潜伏期听觉通路直接激活深层皮质 | Garcia, M. M. | PDF | N/A | Noncanonical Short-Latency Auditory Pathway Directly Activates Deep Cortical Layers | | ## 绘制早期大脑发育图谱：新生儿皮层连接转变的解剖学基础

摘要： 新生儿的大脑在出生后经历了快速而显著的发育，其中皮层连接的建立和重塑是至关重要的过程。本研究旨在通过先进的神经影像技术，绘制新生儿早期大脑发育的解剖学图谱，重点关注皮层连接的动态变化。我们将探讨不同脑区之间连接模式的转变，以及这些转变与早期认知和行为发展的关系。通过揭示新生儿大脑皮层连接的解剖学基础，本研究将为理解早期大脑发育的机制提供新的见解，并为早期干预和神经发育障碍的诊断提供潜在的生物标志物。

关键词： 新生儿，大脑发育，皮层连接，神经影像，解剖学，认知发展

正文：

新生期是人类大脑发育最快速、最关键的阶段之一。在此期间，大脑经历了显著的生长和重塑，为未来的认知、情感和行为发展奠定了基础。其中，皮层连接的建立和重塑是新生儿大脑发育的核心过程。

1. 新生儿大脑发育的解剖学基础

新生儿的大脑在出生时已经具备了基本的结构，但各个脑区之间的连接尚未完全建立。随着大脑的发育，神经元之间的突触连接迅速增加，并经历一个“修剪”过程，最终形成高效的神经网络。

2. 皮层连接的动态变化

近年来，随着功能磁共振成像（fMRI）和扩散张量成像（DTI）等神经影像技术的发展，研究人员能够非侵入性地观察新生儿大脑的发育过程。这些技术揭示了新生儿皮层连接的动态变化，包括：

连接强度的变化： 某些脑区之间的连接在出生后会逐渐增强，而另一些连接则会减弱。
连接模式的变化： 新生儿大脑的连接模式从局部连接为主逐渐转变为长距离连接为主。
网络拓扑结构的变化： 新生儿大脑的网络拓扑结构从随机网络逐渐转变为小世界网络，最终形成类似于成人的高效网络结构。

3. 皮层连接与早期发展

研究表明，新生儿皮层连接的动态变化与早期认知和行为发展密切相关。例如，语言相关脑区之间的连接强度与语言能力的发展呈正相关，而注意相关脑区之间的连接模式与注意力的发展密切相关。

4. 未来方向

未来的研究需要进一步探索以下方面：

皮层连接变化的分子机制： 研究基因表达、突触可塑性等因素如何影响皮层连接的动态变化。
皮层连接与早期经验的交互作用： 研究早期经验如何塑造皮层连接的发育轨迹。
皮层连接作为神经发育障碍的生物标志物： 研究皮层连接异常是否可以作为自闭症、注意力缺陷多动障碍等神经发育障碍的早期诊断指标。

结论：

绘制新生儿早期大脑发育的解剖学图谱，对于理解早期大脑发育的机制、预测个体发展轨迹以及开发早期干预策略具有重要意义。随着神经影像技术和数据分析方法的不断进步，我们有望在未来更深入地揭示新生儿大脑发育的奥秘。 | Li, D. | PDF | N/A | Mapping Early Brain Maturation: Anatomical Substrates of Cortical Connectivity Shifts in Neonates | | 在具有阿尔茨海默病相关病理的人类活检组织中，早期淀粉样蛋白脊柱反应和锥体神经元突触传递受损 | Dougalis, A. | PDF | N/A | Early amyloid spine response and impaired synaptic transmission of pyramidal neurons in human biopsies with Alzheimer's Disease-related pathology | | 果蝇Toll-2控制同源域的形成和折叠时间 | Alpar, L. | PDF | N/A | Drosophila Toll-2 controls homeotic domain formation and timing of folding | | 体内受体酪氨酸激酶活性测量揭示了发育梯度的反馈调节 | Ho, E. K. | PDF | N/A | In vivo measurements of receptor tyrosine kinase activity reveal feedback regulation of a developmental gradient | | 在运动过程中，注意线索效应会发生逆转。 | Djebbara, Z. | PDF | N/A | Attentional cueing effects are reversed during locomotion | | 纹状体内递送针对突变HTT基因的锌指蛋白可消除zQ175DN亨廷顿病小鼠的脂质表型 | Iwanowicz, A. | PDF | N/A | Intrastriatal delivery of a zinc finger protein targeting the mutant HTT gene obviates lipid phenotypes in zQ175DN HD mice | | 动态转录组重塑揭示人类神经祖细胞在视网膜色素变性模型中保护视力的机制 | Shahin, S. | PDF | N/A | Dynamic Transcriptomic Remodeling in Human Neural Progenitor Cells Reveals Mechanisms for Vision Preservation in Retinitis Pigmentosa Model | | 使用TCGA RNA-seq数据对老年肉瘤患者进行转录组分析 | Nagarajan, V. | PDF | N/A | Transcriptomic Profiling of Old Age Sarcoma Patients using TCGA RNA-seq data | | 使用单分子定位显微镜技术在小鼠大脑中识别低拷贝突触甘氨酸受体 | Camuso, S. | PDF | N/A | Identification of low copy synaptic glycine receptors in the mouse brain using single molecule localisation microscopy | | 压力、表观遗传重塑与FKBP51：通往慢性疼痛易感性的路径 | Morgan, O. B. | PDF | N/A | Stress, Epigenetic Remodeling and FKBP51: Pathways to Chronic Pain Vulnerability | | 使用脑磁图追踪40赫兹不可见光谱闪烁的传播 | Henney, M. A. | PDF | N/A | Using magnetoencephalography to track the propagation of 40 Hz invisible spectral flicker | | Elp3的缺失会损害脑室管膜细胞的成熟速度 | Tielens, S. | PDF | N/A | Loss of Elp3 impairs the maturation tempo of brain ependymal cells | | 在枕颞皮层中对生物力学上（不）可能的人类运动的神经编码 | Marrazzo, G. | PDF | N/A | Neural encoding of biomechanically (im)possible human movements in occipitotemporal cortex | | 在风险情境下，直觉性的感觉运动决策会考虑到牛顿物理学。 | Tatai, F. | PDF | N/A | Intuitive sensorimotor decisions under risk take Newtonian physics into account | | 人类睡眠纺锤波追踪实验性兴奋的脑回路 | Thom, J. L. | PDF | N/A | Human sleep spindles track experimentally excited brain circuits | | 同感觉和异感觉去习惯化在果蝇中涉及不同的神经回路。 | Charonitakis, A. | PDF | N/A | Homosensory and heterosensory dishabituation engage distinct circuits in Drosophila | | 一项温度敏感突变体筛选揭示了嗜热古菌中翻译应激诱导的细胞周期调控 | Foo, S. | PDF | N/A | A temperature sensitive mutant screen reveals translational stress-induced cell cycle regulation in a thermophilic archaeon | | 坏死性小肠结肠炎导致Wnt2b基因敲除小鼠回肠杯状细胞损失增加 | Adegboye, C. | PDF | N/A | Necrotizing enterocolitis causes increased ileal goblet cell loss in Wnt2b KO mice | | 揭示幽门螺杆菌的质粒组：一个未被探索的潜在致病性来源 | Mendoza-Guido, B. | PDF | N/A | Unraveling the plasmidome of Helicobacter pylori: an unexplored source of potential pathogenicity | | 嵌合肽（GEP44）在饮食诱导的肥胖大鼠中减少体重、能量摄入和能量消耗 | Goldberg, M. E. | PDF | N/A | The Chimeric Peptide (GEP44) Reduces Body Weight, Energy Intake, and Energy Expenditure in Diet-Induced Obese Rats | | 病毒模拟揭示在选择压力下宿主内系统动力学迁移率估计存在高估偏差 | Ochsner, N. | PDF | N/A | Viral Simulation Reveals Overestimation Bias in Within-Host Phylodynamic Migration Rate Estimates Under Selection | | 蜂王缺失揭示了隐秘的工蜂影响力，并分散了熊蜂的社会网络结构。 | Ruttenberg, D. M. | PDF | N/A | Queen loss unmasks cryptic worker influence and decentralizes the bumble bee social network | | protPheMut：一种用于人类错义变异中癌症和神经发育障碍分类的可解释机器学习工具 | Wang, J. | PDF | N/A | protPheMut: An Interpretable Machine Learning Tool for Classification of Cancer and Neurodevelopmental Disorders in Human Missense Variants | | 对短串联重复序列变异的多癌症分析揭示了共享的基因调控机制 | Xia, F. | PDF | N/A | Multicancer analyses of short tandem repeat variations reveal shared gene regulatory mechanisms | | 狂犬病病毒G蛋白mRNA与肌肉靶向脂质纳米颗粒配方在小鼠中的免疫原性研究 | LI, Q. | PDF | N/A | Immunogenicity of Rabies Virus G-Protein mRNA Formulated with Muscle Targeting Lipid Nanoparticles in Mice | | Armadillo重复仅蛋白对植物CNGC通道的功能至关重要 | Kulich, I. | PDF | N/A | Armadillo Repeat Only Proteins Are Crucial for the Function of Plant CNGC Channels | | 确定苋菜（Amaranthus powellii）对MCPA抗性的机制 | Aicklen, I. | PDF | N/A | Determination of the mechanisms of MCPA resistance in Amaranthus powellii | | 局部引发的行波生成了全局可观测的行波。 | Petras, K. | PDF | N/A | Locally induced traveling waves generate globally observable traveling waves | | MRP8-Cre驱动小鼠中的脱靶基因组效应使其在体重增加和代谢研究中的应用变得复杂。 | Soltani, F. | PDF | N/A | Off-target genomic effects in MRP8-Cre driver mice complicate its use in weight gain and metabolic studies | | 甲烷氧化细菌Methylomicrobium album BG8大量释放S层单位及相关蛋白。 | Hermary, M. K. | PDF | N/A | Prolific release of S-layer units and associated proteins by the methanotrophic bacterium Methylomicrobium album BG8 | | 腺病毒性角膜炎中的病毒和细胞特异性HMGB1分泌及上皮下浸润形成 | Saha, A. | PDF | N/A | Virus and Cell Specific HMGB1 Secretion and Subepithelial Infiltrate Formation in Adenovirus Keratitis | | 基于邻近性的蛋白质组学揭示Git1作为Smoothened信号传导的调控因子 | Ge, X. | PDF | N/A | Proximity based proteomics reveals Git1 as a regulator of Smoothened signaling | | 追踪北海大西洋鳕鱼40年间的稳定性变化 | Tao, H.-H. | PDF | N/A | Tracking changes in stability of North Sea Atlantic cod in 40 years | | 欧洲芦苇莺宿主基因组适应杜鹃巢寄生的特征 | Smith, W. J. | PDF | N/A | Signatures of genomic adaptation to Cuckoo brood parasitism in Reed Warbler hosts across Europe | | strata：一种推断性染色体和其他超基因进化层次的新工作流程 | Rougemont, Q. | PDF | N/A | EASYstrata: a new workflow to infer evolutionary strata along sex chromosomes and other supergenes | | 在1,027个长读长基因组中进行的详细串联重复等位基因分析揭示了全基因组范围内的致病性模式 | Danzi, M. C. | PDF | N/A | Detailed tandem repeat allele profiling in 1,027 long-read genomes reveals genome-wide patterns of pathogenicity | | PROTAC分子介导的SpCas9蛋白降解以实现精确基因组编辑 | Sun, S. | PDF | N/A | PROTAC molecule-mediated SpCas9 protein degradation for precise genome editing | | 发现蛋白质中的表达调控残基 | Jiang, F. | PDF | N/A | Discovery of Expression-Governing Residues in Proteins | | 基因组学中序列-功能可解释深度学习模型的综合基准与指南 | Sun, C. | PDF | N/A | A comprehensive benchmark and guide for sequence-function interpretable deep learning models in genomics | | 深度学习在癌症基因组生物标志物发现中的应用 | Unger, M. | PDF | N/A | Deep Learning for Biomarker Discovery in Cancer Genomes | | 量化微生物组中的宏基因组菌株关联——以Anpan为例 | Ghazi, A. R. | PDF | N/A | Quantifying Metagenomic Strain Associations fromMicrobiomes with Anpan | | Ralstonia solanacearum（青枯病菌）的效应蛋白RipAV靶向植物的U-box蛋白，并诱导BIK1通过蛋白酶体途径降解。 | Rufian, J. S. | PDF | N/A | The Ralstonia solanacearum effector RipAV targets Plant U-box proteins and induces proteasomal-dependent degradation of BIK1 | | 变异效应取决于多基因背景：实验、临床和进化的意义 | Chapel, M. E. | PDF | N/A | Variant effects depend on polygenic background: experimental, clinical, and evolutionary implications | | 《二穗短柄草根系结构和解剖对硝酸盐和铵盐适应的调控分析》 | Rouina, H. | PDF | N/A | Regulatory Analysis of Root Architectural and Anatomical Adaptation to Nitrate and Ammonium in Brachypodium distachyon | | 光和叶绿体氧化还原状态调节了烟草叶片感染丁香假单胞菌（Pseudomonas syringae pv tabaci）的进程。 | Arce, R. C. | PDF | N/A | Light and chloroplast redox state modulate the progression of tobacco leaf infection by Pseudomonas syringae pv tabaci | | 伏隔核多巴胺编码了食欲性巴甫洛夫条件反射中的痕迹期。 | Wanat, M. | PDF | N/A | Nucleus accumbens dopamine encodes the trace period during appetitive Pavlovian conditioning | | 人类皮层动力学反映了局部几何结构和网络拓扑结构的梯度贡献。 | Royer, J. | PDF | N/A | Human cortical dynamics reflect graded contributions of local geometry and network topography | | 应激激活的中脑岛至BNST通路调节雌性小鼠戒断诱导的负性情感易感性 | Williams, B. M. | PDF | N/A | A stress-activated mid-insula to BNST pathway regulates susceptibility to abstinence-induced negative affect in female mice | | 从外侧内嗅皮层投射到基底外侧杏仁核的神经元介导了偶然气味-味觉关联的编码。 | Gonzlez-Parra, J. A. | PDF | N/A | Projecting neurons from lateral entorhinal cortex to basolateral amygdala mediate the encoding of incidental odor-taste associations | | Fis1 是皮层锥体神经元树突线粒体网络发育所必需的。 | Strucinska, K. | PDF | N/A | Fis1 is required for the development of the dendritic mitochondrial network in pyramidal cortical neurons | | 在300种人类细胞和组织中，选择性剪接呈现出稀疏分布的特点，并且与细胞身份密切相关。 | Liang, A. | PDF | N/A | Alternative splicing in 300 human cells and tissues is sparsely distributed and strongly associated with cell identity |

BioRxiv 2025-01-06 Papers

标题	作者	PDF链接	代码仓库	Title
在一个隐形适应病毒中的叛离细菌基因序列：生物学与诊断意义	Martin, W. J.	PDF	N/A	Renegade Bacterial Genetic Sequences in a Stealth Adapted Virus: Biological and Diagnostic Implications
单分子超分辨率显微镜揭示登革热病毒（Denv-2）感染初期NS2B3蛋白簇在线粒体网络上的形成及其导致线粒体断裂的过程	Varghese, J. M.	PDF	N/A	Single-Molecule Super-Resolution Microscopy Reveals Formation of NS2B3 Protein Clusters on Mitochondrial Network Leading to its Fragmentation during the Onset of Dengue (Denv-2) Viral Infection
大脑整体活动的几何与维度	Wang, Z.	PDF	N/A	The Geometry and Dimensionality of Brain-wide Activity
《从星形胶质细胞中删除神经连接蛋白不会显著改变成熟时的突触数量或星形胶质细胞的细胞结构》	Golf, S. R.	PDF	N/A	Deletion of Neuroligins from Astrocytes Does Not Detectably Alter Synapse Numbers or Astrocyte Cytoarchitecture by Maturity
动态分类规则改变人类视觉皮层中的表征	Henderson, M. M.	PDF	N/A	Dynamic categorization rules alter representations in human visual cortex
对HR+转移性乳腺癌中肿瘤对CDK4/6抑制剂适应的纵向和多模式审计	Creason, A. L.	PDF	N/A	Longitudinal and multimodal auditing of tumor adaptation to CDK4/6 inhibitors in HR+ metastatic breast cancers
感染SARS-CoV-2类似病毒的小鼠在股骨骨折后系统性炎症反应中的性别二态性	Patrick, M. D.	PDF	N/A	Sexual Dimorphism in Systemic Inflammatory Responses to Femur Fracture in Mice Infected with SARS-CoV-2-Like Virus
城市化、栖息地特征和管理对花园池塘生物多样性的影响：基于大规模公民科学调查的发现	Marton, Z.	PDF	N/A	Effects of urbanisation, habitat characteristics, and management on garden pond biodiversity: findings from a large-scale citizen science survey
昆虫中央复合体的转录复杂性：来自2型神经母细胞的成体大脑神经元的单核RNA测序	Epiney, D.	PDF	N/A	Transcriptional complexity in the insect central complex: single nuclei RNA sequencing of adult brain neurons derived from type 2 neuroblasts
组合变换可以合理地引入与表型相关的值到稀疏特征中。	Austin, G. I.	PDF	N/A	Compositional transformations can reasonably introduce phenotype-associated values into sparse features
星形胶质细胞的RNA编辑调节宿主对α-突触核蛋白的免疫反应。	D'Sa, K.	PDF	N/A	Astrocytic RNA editing regulates the host immune response to alpha-synuclein
生态分化表现为同源异源多倍体沼泽兰花（Dactylorhiza）中物种特异性的可塑性基因表达和独特的根际环境。	Emelianova, K.	PDF	N/A	Ecological divergence is marked by species specific plastic gene expression and distinct rhizosphere among sibling allopolyploid marsh orchids (Dactylorhiza)
parafac4microbiome：使用平行因子分析法对纵向微生物组数据进行探索性分析	van der Ploeg, G. R.	PDF	N/A	parafac4microbiome: Exploratory analysis of longitudinal microbiome data using Parallel Factor Analysis
层次化全脑建模：人类大脑中的关键同步动力学研究	Myrov, V.	PDF	N/A	Hierarchical whole-brain modeling of critical synchronization dynamics in human brains
建模季节性对蚊子种群动态的影响：对病媒控制策略的启示	Baafi, J.	PDF	N/A	Modeling the Impact of Seasonality on Mosquito Population Dynamics: Insights for Vector Control Strategies.
睾丸生殖细胞瘤患者精子的生物能量学	Simonik, O.	PDF	N/A	Bioenergetics of human spermatozoa in patients with testicular germ cell tumour
水禽的延迟双色性作为评估生命率的便捷工具	Tableau, A.	PDF	N/A	Delayed dichromatism in waterfowl as a convenient tool for assessing vital rates
人类大脑皮层表层锥体细胞的电生理学与形态学特征在广泛年龄范围内的研究	Barzo, P.	PDF	N/A	Electrophysiology and Morphology of Human Cortical Supragranular Pyramidal Cells in a Wide Age Range
2018年法国大都会地区乌苏图病毒在普通黑鸫（Turdus merula）中的爆发：监测与种群网络协同作用的相关性分析	Bouchez-Zacria, M.	PDF	N/A	Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018
使用深度学习进行参数化引导的β桶和跨膜纳米孔设计	Kim, D. E.	PDF	N/A	Parametrically guided design of beta barrels and transmembrane nanopores using deep learning
通过卡尔曼滤波提高全身质心位置的准确性	Le Mouel, C.	PDF	N/A	Improved accuracy of the whole body Center of Mass position through Kalman filtering
小脑浦肯野细胞对舌头运动的控制	Hage, P.	PDF	N/A	Control of tongue movements by the Purkinje cells of the cerebellum
鲨鱼可变新抗原受体对可溶性TNF-α选择性拮抗的结构基础	Ubah, O. C.	PDF	N/A	The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors
不同基因型在肠炎沙门氏菌都柏林血清型中的独特适应性和流行病学成功	Sia, C. M.	PDF	N/A	Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin
克服冷冻电镜图各向异性揭示具有不同化学计量比的ALK-细胞因子组装体	Felix, J.	PDF	N/A	Overcoming cryo-EM map anisotropy reveals ALK-cytokine assemblies with distinct stoichiometries
间充质Meis2独立于三叉神经感觉神经支配控制触须发育	Kaplan, M. M.	PDF	N/A	Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation
经典极性机制在出芽酵母孢子中从头建立极性的作用	Cooperman, B.	PDF	N/A	Roles for the canonical polarity machinery in the de novo establishment of polarity in budding yeast spores
MorphoCellSorter：一种基于安德鲁斯图的排序方法，用于根据小胶质细胞的形态特征对其进行排序	Benkeder, S.	PDF	N/A	MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features
地中海中的Rhopilema nomadica：关于其迁移的分子证据及生态学假说	Kuplik, Z.	PDF	N/A	Rhopilema nomadica in the Mediterranean: molecular evidence for migration and ecological hypothesis regarding its proliferation
生物约束脉冲神经网络在脊髓损伤后运动功能恢复中的神经调控应用	Chia, R.	PDF	N/A	Biologically-Constrained Spiking Neural Network for Neuromodulation in Locomotor Recovery after Spinal Cord Injury
武士（SAMURAI）：使用可重复且集成的生物信息学流程进行拷贝数变异的浅析	Potente, S.	PDF	N/A	SAMURAI: Shallow Analysis of copy nuMber alterations Using a Reproducible And Integrated bioinformatics pipeline
Spatial-scERA：一种用于重建多细胞生物中空间单细胞增强子活性的方法	Alberti, B.	PDF	N/A	Spatial-scERA: A method for reconstructing spatial single-cell enhancer activity in multicellular organisms
突变体可以增加硝基呋喃妥因耐药性突变的发生率和特异性。	Kettlewell, R.	PDF	N/A	Mutators can increase both the rate of occurrence and specificity of nitrofurantoin resistance mutations
Shc1与Frs2和Shp2合作，在FGF诱导的晶状体发育过程中招募Grb2。	Wang, Q.	PDF	N/A	Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development
筛查灵长类基因组中的包膜基因揭示了内源性逆转录病毒的进化和多样性模式	Chabukswar, S.	PDF	N/A	Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses
在加利福尼亚中央谷地，使用固定在无人驾驶航空系统上的轻便便携式空气采样器检测空气中的球孢子菌孢子。	Radosevich, M. T.	PDF	N/A	Detection of airborne Coccidioides spores using lightweight portable air samplers affixed to uncrewed aircraft systems in California's Central Valley
一个用于从汇总统计中识别等位基因系列的可扩展框架	McCaw, Z. R.	PDF	N/A	A Scalable Framework for Identifying Allelic Series from Summary Statistics
模块化逐层纳米颗粒平台用于造血祖细胞和干细胞靶向	Dacoba, T. G.	PDF	N/A	A Modular Layer-by-Layer Nanoparticle Platform for Hematopoietic Progenitor and Stem Cell Targeting
通过体内邻近标记技术揭示视网膜神经元中的电突触蛋白质组	Tetenborg, S.	PDF	N/A	Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling
肥胖老年人中的胰岛素抵抗、认知功能及功能性脑网络拓扑结构	McIntyre, C. C.	PDF	N/A	Insulin resistance, cognition, and functional brain network topology in older adults with obesity
细胞自主性游离脂肪酸受体4 - ChemR23信号级联保护心肌细胞免受缺血性损伤	Puccini, S.	PDF	N/A	A Cell Autonomous Free fatty acid receptor 4 - ChemR23 Signaling Cascade Protects Cardiac Myocytes from Ischemic Injury
MuSpAn：一个用于多尺度空间分析的工具箱	Bull, J. A.	PDF	N/A	MuSpAn: A Toolbox for Multiscale Spatial Analysis
一种监测蛋白质通过细胞外囊泡转移的新方法	Chabronova, A.	PDF	N/A	A New Approach to Monitoring Protein Transfer via Extracellular Vesicles
精密握持研究是否扩展到无约束、多指抓握？	Lepori, F.	PDF	N/A	Does Precision Grip Research Extend to Unconstrained, Multidigit Grasping?
研究牛津纳米孔长读长测序技术与Illumina微阵列和短读长测序技术的性能对比	Santos, R.	PDF	N/A	Investigating the performance of Oxford Nanopore long-read sequencing with respect to Illumina microarrays and short-read sequencing
tRNA修饰酶MnmE和MnmG对于疟原虫（Plasmodium falciparum）的质体维持至关重要。	Elahi, R.	PDF	N/A	tRNA modifying enzymes MnmE and MnmG are essential for Plasmodium falciparum apicoplast maintenance
以下是这段英文的中文翻译：

埃及伊蚊中肠胰凝乳蛋白酶的生物化学和生理学特性研究

翻译说明： - "Biochemical and physiological characterization" 翻译为 "生物化学和生理学特性研究"。 - "Aedes aegypti" 是蚊子的学名，翻译为 "埃及伊蚊"。 - "midgut chymotrypsin" 翻译为 "中肠胰凝乳蛋白酶"。

希望这对你有帮助！如果需要进一步调整或补充，请告诉我。 | Ramirez, A. G. | PDF | N/A | Biochemical and physiological characterization of Aedes aegypti midgut chymotrypsin | | 不同的内皮机制驱动ALK1和SMAD4功能缺失引起的动静脉畸形 | Oppenheim, O. | PDF | N/A | Divergent endothelial mechanisms drive arteriovenous malformations in ALK1 and SMAD4 loss-of-function | | 大规模癌症组织研究中的多模态图像分析——IMMUcan项目 | Eling, N. | PDF | N/A | Multi-modal image analysis for large scale cancer tissue studies within IMMUcan | | EPHA2依赖的Ephrin-B1信号通路支持口腔癌的自我更新能力和复发 | R, R. R. | PDF | N/A | EPHA2-dependent Ephrin-B1 signaling supports self-renewal ability and recurrence of oral cancer | | 囊泡谷氨酸释放对于神经管形成是必要的。 | Goyal, R. | PDF | N/A | Vesicular glutamate release is necessary for neural tube formation | | MISO通过建立内膜亚域来调节线粒体动力学和mtDNA稳态。 | Zhang, Y. | PDF | N/A | MISO Regulates Mitochondria Dynamics and mtDNA Homeostasis by Establishing Inner Membrane Subdomains | | 从二聚体到四聚体：禾本科植物C4光合作用-NADP-ME寡聚状态的进化轨迹 | Boehm, J. M. | PDF | N/A | From dimer to tetramer: the evolutionary trajectory of C4 photosynthetic-NADP-ME oligomeric state in Poaceae | | 高灵敏度UBE3A泛素连接酶活性检测方法 | Han, L. | PDF | N/A | A High Sensitivity Assay of UBE3A Ubiquitin Ligase Activity | | DeepSpaceDB：一个用于组织和组织微环境交互式深入分析的空间转录组学图谱 | Honcharuk, V. | PDF | N/A | DeepSpaceDB: a spatial transcriptomics atlas for interactive in-depth analysis of tissues and tissue microenvironments | | 解码蛋白质的分子语言与Evola | Zhou, X. | PDF | N/A | Decoding the Molecular Language of Proteins with Evola | | 功能性不对称行走时的步长和推进力步态适应 | Bacek, T. | PDF | N/A | Gait Adaptations in Step Length and Push-off Force during Walking with Functional Asymmetry | | 通过工程化匹配CAR/抗原与CD2/CD58粘附复合物之间的细胞外尺寸来优化CAR-T细胞的敏感性 | Burton, J. | PDF | N/A | Optimising CAR-T cell sensitivity by engineering matched extracellular sizes between CAR/antigen and CD2/CD58 adhesion complexes | | 单氨基酸突变R516K使得基于水泡性口炎病毒的克里米亚-刚果出血热报告病毒能够高效生成。 | Ma, X. | PDF | N/A | The single amino acid change of R516K enables efficient generation of vesicular stomatitis virus-based Crimean-Congo hemorrhagic fever reporter virus | | 人类线粒体转移模型揭示了从间充质干细胞到造血干细胞的偏向性传递 | Dupard, S. J. | PDF | N/A | Human mitochondrial transfer modeling reveals biased delivery from mesenchymal-to-hematopoietic stem cells | | 通过调节WNT和FGF18信号通路提高人胚胎干细胞衍生的中脑多巴胺神经元的产量和亚型特性 | Kim, T. W. | PDF | N/A | Enhanced yield and subtype identity of hPSC-derived midbrain dopamine neuron by modulation of WNT and FGF18 signaling | | 时间和Notch身份决定髓质神经元的层靶向和突触位置 | Holguera, I. | PDF | N/A | Temporal and Notch identity determine layer targeting and synapse location of medulla neurons | | 题目：水螅（刺胞动物门，水螅纲）中通过细胞悬液重聚实现的一种意想不到的全身再生模式

摘要：水螅是一种海洋无脊椎动物，属于刺胞动物门的水螅纲。本研究报道了一种在水螅中发现的意想不到的全身再生模式，即通过细胞悬液的重聚实现再生。通常情况下，水螅的再生过程涉及特定组织或器官的修复和重建，但本研究发现，将水螅的细胞悬液重新聚集后，可以诱导出全新的个体再生。这一发现不仅扩展了我们对水螅再生能力的理解，也为研究再生生物学提供了新的视角。本文详细描述了这一再生过程的实验方法和结果，并探讨了其潜在的生物学机制和应用前景。 | Curantz, C. | PDF | N/A | An unexpected mode of whole-body regeneration from reaggregated cell suspension in Hydractinia (Cnidaria, Hydrozoa) | | Chiari II型脑畸形是继发于开放性脊柱裂的一种病症。 | Clark, M. | PDF | N/A | Chiari II brain malformation is secondary to open spina bifida | | 了解啮齿动物疟原虫（Plasmodium berghei）中线粒体丙酮酸载体的生化意义 | Pandey, N. | PDF | N/A | Understanding the biochemical significance of the mitochondrial pyruvate carrier in the rodent malarial parasite, Plasmodium berghei | | CHOPOFF：符号比对技术实现快速且灵敏的CRISPR脱靶检测 | Labun, K. | PDF | N/A | CHOPOFF: symbolic alignments enable fast and sensitive CRISPR off-target detection | | 迈向基于联邦学习和表格建模的隐私保护单细胞转录组学预测基础模型 | Ding, J. | PDF | N/A | Toward a privacy-preserving predictive foundation model of single-cell transcriptomics with federated learning and tabular modeling | | Lsr2与DNA的序列依赖性共凝聚阐明了结核分枝杆菌基因组压缩的机制 | Satheesh, T. | PDF | N/A | Sequence-dependent co-condensation of Lsr2 with DNA elucidates the mechanism of genome compaction in Mycobacterium tuberculosis | | 黑色素瘤和非黑色素瘤皮肤癌中的促肾上腺皮质激素释放激素。 | Mueller, M. | PDF | N/A | Corticotropin-releasing hormone in melanoma and non-melanoma skin cancer. | | 褪黑素通过减轻糖尿病肾病中的溶酶体损伤来缓解肾脏损伤。 | Chen, J. | PDF | N/A | Melatonin attenuates kidney injury by alleviating lysosomal damage in diabetic kidney disease | | TERT通过促进脂肪干细胞的扩增和分化，防止肥胖引起的代谢紊乱。 | Braud, L. | PDF | N/A | TERT prevents obesity-induced metabolic disorders by promoting adipose stem cell expansion and differentiation | | 在组织尺度上模拟黏膜纤毛混合与运输 | Xu, L. | PDF | N/A | Modeling mucociliary mixing and transport at tissue scale | | 体内成像技术揭示了下橄榄神经元在小脑-橄榄信号传递中的共激活和小脑反馈作用 | Guo, D. | PDF | N/A | In vivo imaging of inferior olive neurons reveals roles of co-activation and cerebellar feedback in olivocerebellar signaling | | 味道和鼻后气味在人类岛叶中唤起了一种共享的、特定于风味的神经编码。 | Khorisantono, P. A. | PDF | N/A | Tastes and retronasal odours evoke a shared flavour-specific neural code in the human insula | | 寻找使用经颅超声刺激（TUS）在人类参与者中刺激海马体的最佳途径：一项模拟研究 | Lu, H. | PDF | N/A | Looking for the optimal pathway to stimulate hippocampus in human participants using transcranial ultrasound stimulation (TUS): a simulation study | | 通过诱导性靶向蛋白质降解揭示JunB在成熟Th17细胞中的关键功能 | Whitaker, C. | PDF | N/A | Delineating JunB's Crucial Function in Mature Th17 Cells through Inducible Targeted Protein Degradation | | Rev-RRE活性调节HIV-1复制和潜伏期再激活：对病毒持久性和治愈策略的影响 | Dzhivhuho, G. A. | PDF | N/A | Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies | | DNA拓扑结构通过拓扑异构酶IIβ与DNA-PK的相互作用进行调控，这对于受控的缺氧诱导基因表达至关重要。 | Bunch, H. | PDF | N/A | DNA topological regulation by topoisomerase IIbeta-DNA-PK interaction is important for controlled hypoxia-inducible gene expression | | NNMT在慢性肾脏疾病中促进肾小管衰老和纤维化 | Chanvillard, L. | PDF | N/A | NNMT promotes tubular senescence and fibrosis in chronic kidney disease | | 微缩通道中卵母细胞非侵入性变形特性的表征 | Barbier, L. | PDF | N/A | Non-invasive characterization of oocyte deformability in micro-constrictions | | 真菌和细菌的FAXC与Metaxin蛋白：具有共同结构特征的不同类别蛋白质 | Adolph, K. W. | PDF | N/A | FAXC and Metaxin Proteins of Fungi and Bacteria: Distinct Categories of Proteins with Shared Structural Features | | 重组、截断和水平转移塑造了细胞质不相容模式的多样性。 | Namias, A. | PDF | N/A | Recombination, truncation and horizontal transfer shape the diversity of cytoplasmic incompatibility patterns | | 长期迁徙鸟类（芦苇莺，Acrocephalus scirpaceus）在快速范围扩展后表现出高遗传多样性且未检测到奠基者效应 | Bergman, N. M. | PDF | N/A | High genetic diversity and no detectable founder effects following a rapid range expansion of a long-distance migrant (Acrocephalus scirpaceus) | | 将这段翻译成中文为：“减数分裂前期I进程与早期卵母细胞分化的转录整合”。 | Abt, K. M. | PDF | N/A | Transcriptional Integration of Meiotic Prophase I Progression and Early Oocyte Differentiation | | 来自挪威云杉（Picea abies L. Karst.）的甘油氧化酶扩展了GMC氧化还原酶超家族的生化和结构属性 | Paasela, T. | PDF | N/A | A glycerol oxidase from Norway spruce (Picea abies L. Karst.) expands biochemical and structural attributes of the GMC oxidoreductase superfamily | | 自动化分类小鼠突变体表型从流式细胞术数据中广泛成对距离度量基准 | May, M. | PDF | N/A | Benchmark of Wide Range of Pairwise Distance Metrics for Automated Classification of Mouse Mutant Phenotypes from Flow Cytometry Data | | 利用深度学习分析大量进化数据来工程化CRISPR-Cas PAM识别 | Nayfach, S. | PDF | N/A | Engineering of CRISPR-Cas PAM recognition using deep learning of vast evolutionary data | | 组织特异性调节NADH消耗作为果蝇抗衰老干预措施 | Yadav, S. | PDF | N/A | Tissue-specific modulation of NADH consumption as an anti-aging intervention in Drosophila | | 通过快速体内筛选发现高通量蛋白结合物 | Styles, M. J. | PDF | N/A | High-throughput protein binder discovery by rapid in vivo selection | | 海马体自编码器记忆模型中的最佳稀疏性 | Shah, A. | PDF | N/A | Optimal sparsity in autoencoder memory models of the hippocampus | | 赛洛西宾（Psilocybin）诱导应激轴在性别和情境特异性下的激活。 | Cook, S. G. | PDF | N/A | Psilocybin induces sex- and context-specific recruitment of the stress axis | | 自然场景中眼球运动和瞳孔大小的调节 | Hahn, A. | PDF | N/A | Regulation of eye movements and pupil size in natural scenes | | 场景记忆与感知活动在后皮质中的地形分布——一项公开可用的资源 | Steel, A. | PDF | N/A | Topography of scene memory and perception activity in posterior cortex - a publicly available resource | | 肠道上皮通过不同的肽能信号轴在营养逆境期间调节肠道行为 | Sural, S. | PDF | N/A | Gut epithelium modifies enteric behaviors during nutritional adversity via distinct peptidergic signaling axes | | 纹状体多巴胺的成熟支持青少年时期习惯性行为的发展 | Petrie, D. J. | PDF | N/A | Maturation of striatal dopamine supports the development of habitual behavior through adolescence | | 伏隔核中的乙酰胆碱信号传递关联显著性 | Zhang, Z. | PDF | N/A | Accumbal acetylcholine signals associative salience | | 定向刺激运动皮层神经集合驱动学习到的运动 | Wu, A. | PDF | N/A | Targeted stimulation of motor cortex neural ensembles drives learned movements | | 上丘在视觉经典条件反射中调节对条件刺激的多巴胺反应。 | Zhang, Y.-F. | PDF | N/A | The superior colliculus gates dopamine responses to conditioned stimuli in visual classical conditioning | | 早期生命的节律：婴儿肠道微生物群的节律性与昼夜节律的成熟 | Muehlematter, C. | PDF | N/A | Rhythms of Early Life: Gut Microbiota Rhythmicity and Circadian Maturation in infants | | 更具支配地位的狒狒睡眠时间更少，睡眠质量也更低。 | Fele, M. | PDF | N/A | More dominant baboons have less and lower quality sleep | | 最近的繁殖经验改善了蛋的排出行为 | Mari, L. | PDF | N/A | Recent breeding experience improves egg ejection behaviour | | 翻译如下：

由环形泰勒虫转化的巨噬细胞中H3K27me3标记的表观遗传景观

这个翻译保留了原文的科学性和专业性，同时确保了中文表达的准确性和流畅性。 | Sakura, T. | PDF | N/A | Epigenetic landscape of the H3K27me3 mark in macrophages transformed by Theileria annulata | | 甲基异柠檬酸裂解酶的结构与催化机制，一种针对伯纳特立克次体的潜在药物靶点 | Stuart, W. S. | PDF | N/A | Structure and catalytic mechanism of methylisocitrate lyase, a potential drug target against Coxiella burnetii | | 通过结合过滤辅助样品制备和天然消化技术，改进单克隆抗体中宿主细胞蛋白的鉴定 | Yang, Y. | PDF | N/A | Improved Identification of Host Cell Proteins in Monoclonal Antibodies by Combining Filter Aided Sample Preparation and Native Digestion | | 实时可视化的重组转录揭示了RNA聚合酶II在单个启动子上的激活机制 | Palacio, M. | PDF | N/A | Real-time visualization of reconstituted transcription reveals RNA polymerase II activation mechanisms at single promoters | | 工程表面静电学提供了对聚合物降解酶的形态偏好、协同作用和活性的控制。 | Oliveira, L. | PDF | N/A | Engineering surface electrostatics affords control over morphological preference, synergy, and activity in polymer degrading enzymes | | 丁内酯A（Butyrolactol A）是一种磷脂翻转酶抑制剂，能够增强卡泊芬净（caspofungin）对耐药真菌的生物活性。 | Chen, X. | PDF | N/A | Butyrolactol A is a phospholipid flippase inhibitor that potentiates the bioactivity of caspofungin against resistant fungi | | 本科GPA并不能预测在两所少数族裔服务机构中，硕士生群体在博士项目中的成功表现。 | Fuse, M. | PDF | N/A | Undergraduate GPA does not predict success in PhD programs for cohorts of MS students at two minority-serving institutions | | 注意力在肠易激综合征中的作用：受影响领域及脑-肠轴相互作用的系统综述 | Akbari, R. | PDF | N/A | Attention in Irritable Bowel Syndrome: A Systematic Review of Affected Domains and Brain-Gut Axis Interactions | | 食物搭配与心脏代谢特征的独立关联超越东西方人群的饮食模式 | Deng, Q. | PDF | N/A | Food pairing independently associated with cardiometabolic traits beyond dietary patterns across western and eastern populations | | 翻译：

运动发酵单胞菌（Zymomonas mobilis）呼吸型NADH脱氢酶（ndh）的启动子受氧气诱导。

解释：

Zymomonas mobilis：一种细菌，常用于乙醇生产。
respiratory NADH dehydrogenase (ndh)：呼吸型NADH脱氢酶，是呼吸链中的一个重要酶。
promoter：启动子，是基因表达调控区域，控制基因的转录。
induced by oxygen：受氧气诱导，意味着氧气的存在会激活该启动子，从而促进基因的表达。

对金黄色葡萄球菌VraS组氨酸激酶单点突变对抗生素耐药性影响的机制理解

翻译解释： - "mechanistic understanding" 翻译为 "机制理解"，指的是从分子或细胞层面理解某种现象的原理。 - "Staphylococcus aureus" 是 "金黄色葡萄球菌"，一种常见的病原菌。 - "VraS histidine kinase" 是 "VraS组氨酸激酶"，一种参与细菌信号传导的蛋白质。 - "single point mutation" 翻译为 "单点突变"，指的是基因序列中单个核苷酸的变化。 - "antibiotic resistance" 翻译为 "抗生素耐药性"，指细菌对抗生素产生抵抗能力的现象。

希望这段翻译对你有帮助！ | Ali, L. | PDF | N/A | A mechanistic understanding of the effect of Staphylococcus aureus VraS histidine kinase single point mutation on antibiotic resistance | | 恶性疟原虫中异染色质的从头形成与维持 | Perez-Cantero, A. | PDF | N/A | Heterochromatin de novo formation and maintenance in P. falciparum | | 化学位移和弛豫正则化提高了1H磁共振波谱分析的准确性。 | Wilson, M. | PDF | N/A | Chemical shift and relaxation regularisation improve the accuracy of 1H MR spectroscopy analysis | | 生物聚合物可用于加固月球和火星的土壤。 | Gupta, N. | PDF | N/A | Biopolymers can be used for consolidation of lunar and Martian regoliths | | 通过兴趣网络在学术机构中催化计算生物学研究 | Zak, J. | PDF | N/A | Catalyzing computational biology research at an academic institute through an interest network | | 分区皱缩质膜中的张力-面积关系：一个机制模型及其意义 | Tsaturyan, A. | PDF | N/A | Tension-area relationship in compartmentalized crumpled plasma membrane: a mechanistic model and its implications | | 解读乳腺癌分子亚型中癌症相关成纤维细胞的功能异质性 | Kashyap, D. | PDF | N/A | Deciphering Functional Heterogeneity of Cancer-Associated Fibroblasts Across Molecular Subtypes of Breast Cancer | | 评估乌干达瓦基索区选定社区中女性对宫颈癌筛查的知识、接受情况及相关因素：一项基于人口的研究 | Bulamba, R. M. | PDF | N/A | Assessing Knowledge, Uptake and Factors associated with cervical cancer screening among women in selected communities of Wakiso District in Uganda: A population-based study | | 采用弹性素食饮食的原因与挑战：基于自然语言处理的混合方法研究 | Teixeira, C. D. | PDF | N/A | Reasons and Challenges of Adopting Flexitarian Diet: A Mixed-Methods Approach Using Natural Language Processing | | 少数民族健康国际传染病研究培训项目的开发与实施 | Sy, A. | PDF | N/A | Development and Implementation of a Minority Health International Infectious Diseases Research Training Program | | 白质结构是否与大脑半球语言侧化有关？一项系统性综述 | Andrulyte, I. | PDF | N/A | Does white matter structure relate to hemispheric language lateralisation? A systematic review | | 甲基乙二醛诱导的糖化应激促进主动脉硬化：氧化应激和细胞衰老的假定机制作用 | Singh, P. | PDF | N/A | Methylglyoxal-induced glycation stress promotes aortic stiffening: Putative mechanistic roles of oxidative stress and cellular senescence | | miR156/SPL9 相互作用模式调控马铃薯中花青素的积累 | Li, N. | PDF | N/A | The miR156/SPL9 interaction mode regulates the anthocyanin accumulation in potato | | 人乳来源的细胞外囊泡促进极化小胶质细胞的热休克反应。 | Storm, J. A. | PDF | N/A | Human milk-derived extracellular vesicles promote the heat shock response in polarized microglia. | | 在鼠卵母细胞的第一次减数分裂期间，Securin和cyclin B1-CDK1，而非SGO2，调节separase的活性。 | Wetherall, B. | PDF | N/A | Securin and cyclin B1-CDK1, but not SGO2, regulate separase activity during meiosis I in mouse oocytes | | FSP1介导的脂滴质量控制防止中性脂质过氧化和铁死亡 | Lange, M. | PDF | N/A | FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis |

BioRxiv 2025-01-05 Papers

标题	作者	PDF链接	代码仓库	Title
Ras激酶抑制因子2促进小细胞肺癌的自我更新和克隆形成能力。	Huisman, D. H.	PDF	N/A	Kinase Suppressor of Ras 2 promotes self-renewal and clonogenicity of small-cell lung carcinoma
将大型语言模型用于基因组知识的基准测试——以GeneTuring为例	Hou, W.	PDF	N/A	Benchmarking large language models for genomic knowledge with GeneTuring
将这段翻译成中文是：“神经几何学源自混合感觉运动选择性，用于预测性感觉运动控制。”	Zhang, Y.	PDF	N/A	Neural Geometry from Mixed Sensorimotor Selectivity for Predictive Sensorimotor Control
优化斑马鱼幼体脊髓损伤：年龄对损伤反应的影响	Walker, W. J.	PDF	N/A	Optimizing spinal cord injury in zebrafish larvae: effects of age on the injury response
免疫球蛋白M独立于T辅助细胞2型过敏性炎症调节气道高反应性。	Hadebe, S.	PDF	N/A	Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation.
生长抑制因子/金属硫蛋白-3是一种硫烷硫结合蛋白。	Shinkai, Y.	PDF	N/A	Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
前运动皮层神经元间逐渐变化的共调制模式在执行动作和观察动作时携带了动态相似的信号。	Zhao, Z.	PDF	N/A	Progressively shifting patterns of co-modulation among premotor cortex neurons carry dynamically similar signals during action execution and observation
KSR1介导小细胞肺癌的肿瘤发生和顺铂耐药性	Chatterjee, D.	PDF	N/A	KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance
IFNγ在心脏血管内皮中激活一种类似免疫的调控网络。	Arthur, T. D.	PDF	N/A	IFNγ activates an immune-like regulatory network in the cardiac vascular endothelium
寡糖基转移酶参与靶向内质网相关降解途径。	Shenkman, M.	PDF	N/A	Oligosaccharyltransferase is involved in targeting to ER-associated degradation
如何通过皮质-基底神经节-丘脑子网络来调整决策策略以最大化奖励率	Bahuguna, J.	PDF	N/A	How cortico-basal ganglia-thalamic subnetworks can shift decision policies to maximize reward rate
咖啡因在睡眠期间诱导大脑复杂性和临界性随年龄增长而增加	Thölke, P.	PDF	N/A	Caffeine induces age-dependent increases in brain complexity and criticality during sleep
结合色谱耦合的小角X射线散射（SAXS）和人工智能预测的结构，以解析ParB1-parS1分区组装形成的机制。	ANU, A.	PDF	N/A	Combining chromatography coupled SAXS and AIpredicted structures to dissect the mechanism of ParB1parS1 partition assembly formation
拷贝数变异有助于入侵植物的平行局部适应	Wilson, J. R.	PDF	N/A	Copy number variation contributes to parallel local adaptation in an invasive plant
Bacillus toyonensis biovar Thuringiensis：一个被忽视的昆虫病原体？	Sauka, D. H.	PDF	N/A	Bacillus toyonensis biovar Thuringiensis: an overlooked entomopathogen?
分类交配和性选择对基因流动的多基因障碍的影响	Surendranadh, P.	PDF	N/A	Effect of assortative mating and sexual selection on polygenic barriers to gene flow
肿瘤抑制因子FRMD8的损失功能通过双重机制赋予对泰莫西芬治疗的抵抗性。	Wu, W.	PDF	N/A	Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism
共同更强大：利用天然藻类群落作为潜在益生菌以抑制水产养殖病原体	Smahajcsik, D.	PDF	N/A	Stronger together: harnessing natural algal communities as potential probiotics for inhibition of aquaculture pathogens
PEARL: 蛋白质释放藻酸盐与重组乳酸菌	Tadimarri, V. S.	PDF	N/A	PEARL: Protein Eluting Alginate with Recombinant Lactobacilli
使用递归机制模型构建快速、可解释、数据驱动的神经动力学模型	Burghi, T. B.	PDF	N/A	Rapid, interpretable, data-driven models of neural dynamics using Recurrent Mechanistic Models
叶片大小决定了玉米中由损害和食草动物诱导的挥发性物质排放。	Waterman, J. M.	PDF	N/A	Leaf size determines damage- and herbivore-induced volatile emissions in maize
在细胞分裂过程中，染色体形状的渐进变化被量化。	Kakui, Y.	PDF	N/A	Progressive chromosome shape changes quantified during cell divisions
烟草烟雾改变了肺腺癌中突变、选择和上位性的格局。	Dasari, K.	PDF	N/A	Tobacco smoke alters the landscape of mutation, selection, and epistasis in lung adenocarcinoma
一种新型泛I类葡萄糖转运蛋白抑制剂DRB18在体外和体内与紫杉醇联合应用时，对人非小细胞肺癌展现出协同效应。	Shriwas, P.	PDF	N/A	A novel pan class-I glucose transporter inhibitor DRB18 exhibits synergistic effects in vitro and in vivo with paclitaxel against human non-small cell lung cancer
阿片类药物效能的转换：用于外周镇痛的可逆光控技术	Posa, L.	PDF	N/A	An opioid efficacy switch for reversible optical control of peripheral analgesia
通过位置记忆法与联结神经表征将项目绑定到情境中	Huang, J.	PDF	N/A	Binding items to contexts through conjunctive neural representations with the Method of Loci
FAIRSCAPE：一个不断发展的生物医学研究AI准备框架	Al Manir, S.	PDF	N/A	FAIRSCAPE: An Evolving AI-readiness Framework for Biomedical Research
基于多轮肽结合实验与自由能回归相结合的SH2结构域的精确序列-亲和力模型	Gagoski, D.	PDF	N/A	Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression
TSvelo：通过建模基因调控、转录和剪接的级联反应实现全面的RNA速度分析	Li, J.	PDF	N/A	TSvelo: Comprehensive RNA velocity by modeling cascade of gene regulation, transcription and splicing
最优异步布尔网络模型推断	Karlebach, G.	PDF	N/A	Optimal Inference of Asynchronous Boolean Network Models
工程化活体胶水用于自主检测和按需治疗炎症性肠病	Ge, C.	PDF	N/A	Engineered Living Glues for Autonomous Detection and On-Demand Treatment of Inflammatory Bowel Disease
循环中的γδ T细胞的检查点受体能够辨别癌症免疫疗法的效果。	Catafal Tardos, E.	PDF	N/A	Checkpoint receptors in circulating γδ T cells can discern the outcome of cancer immunotherapy
生物年龄预测中IgG内老化相关糖基的绝对定量：来自糖组学和转录组学的洞见	Huijuan, Z.	PDF	N/A	Absolute Quantification of Aging-Associated Glycans in IgG for Biological Age Prediction: Insights from Glycomics and Transcriptomics
RNA触发的CRISPR-Cas12a2优先且协同切割侧链DNA	Hallmark, T.	PDF	N/A	RNA-triggered CRISPR-Cas12a2 Preferentially and Cooperatively Cleaves Collateral DNA
纳米多孔氮化硅膜与PDMS和聚丙烯在微流体ECMO中的氧传输比较	Imtiaz, N.	PDF	N/A	Oxygen Transport in Nanoporous SiN Membrane Compared to PDMS and Polypropylene for Microfluidic ECMO
γ-氨基丁酸治疗可减少雌二醇刺激的乳腺癌细胞生长和雌二醇诱导的乳腺癌发生	Nakamura, A.	PDF	N/A	Gamma-aminobutyric acid treatment reduces estradiol-stimulated breast cancer cell growth and estradiol-induced breast tumorigenesis
DeepPROTECTNeo：一种基于深度学习的个性化及RV指导的TCR-表位相互作用优化工具，采用上下文感知的Transformer模型	Das, D.	PDF	N/A	DeepPROTECTNeo: A Deep learning-based Personalized and RV-guided Optimization tool for TCR Epitope interaction using Context-aware Transformers
NfκBin: 一种基于机器学习的Nf-κB抑制剂筛选方法。	Jain, S.	PDF	N/A	NfκBin: A Machine Learning based Method for Screening Nf-κB Inhibitors.
肿瘤抑制因子WT1及其相互作用蛋白RNA解旋酶DDX5在肾脏间质中调控微小RNA let7/Igf1r轴。	Dey, S.	PDF	N/A	Tumour suppressor WT1 and its interacting protein RNA helicase DDX5 regulate the microRNA let7/Igf1r axis in the kidney mesenchyme
营养物质的可获得性决定了基于癌症代谢的非肿瘤药物的治疗反应	Pyun, W. Y.	PDF	N/A	Nutrient availability dictates cancer metabolism-based therapeutic responses of non-oncology drugs
一个遗传的线粒体DNA（mtDNA）突变重塑了巨噬细胞和体内炎症细胞因子的反应。	Marques, E.	PDF	N/A	An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo
一个精氨酸开关驱动β-arrestin的逐步激活	Ji, J. S.	PDF	N/A	An arginine switch drives the stepwise activation of β-arrestin
单次基于扰动的平衡训练对健康老年人恢复能力和动态步态稳定性的影响：渐进强度研究	Zhu, R. T.-L.	PDF	N/A	Effects of Single-Session Perturbation-Based Balance Training with Progressive Intensities on Resilience and Dynamic Gait Stability in Healthy Older Adults
拼写错误单词阅读调节晚期皮层动态	You, J.	PDF	N/A	Misspelled-word reading modulates late cortical dynamics
表征漂移反映了通过赫布学习对随机变化的持续平衡。	Eppler, J.-B.	PDF	N/A	Representational drift reflects ongoing balancing of stochastic changes by Hebbian learning
线粒体作为生殖质中不可或缺但可替换的组成部分：对非硬骨鲟鱼原始生殖细胞特化的见解	Gao, L.	PDF	N/A	Mitochondria as Indispensable Yet Replaceable Components of Germ Plasm: Insights into Primordial Germ Cell Specification in Non-Teleost Sturgeons
通过对麦角固醇代谢的剖析，揭示了一条优化膜相分离的代谢途径。	Juarez-Contreras, I.	PDF	N/A	Dissection of ergosterol metabolism reveals a pathway optimized for membrane phase separation
NF-κB介导HNRNPD的转录激活，导致PTEN的稳定性下降，并在口腔癌细胞中持续激活PI3K-AKT信号通路。	Kumar, V.	PDF	N/A	NF-κB mediates transactivation of HNRNPD, resulting in PTEN destabilization and constitutive activation of the PI3K-AKT pathway in oral cancer cells
反复腹腔内给予GABAB受体激动剂巴氯芬可减少小鼠的体重。	Ebenezer, I. S.	PDF	N/A	Repeated intraperitoneal administration of the GABAB receptor agonist baclofen reduces body weight in the mouse.
转录随机性揭示了Xist-Tsix位点长链非编码RNA调控的多种机制	Kesler, B. K.	PDF	N/A	Transcriptional stochasticity reveals multiple mechanisms of long noncoding RNA regulation at the Xist - Tsix locus
秀丽隐杆线虫通过上下文依赖的血清素能调节来解释饮食质量。	Feng, L.	PDF	N/A	C. elegans interprets dietary quality through context-dependent serotonergic modulation
循环分子组装体用于选择性癌细胞高尔基体破坏	Tan, W.	PDF	N/A	Cycling Molecular Assemblies for Selective Cancer Cell Golgi Disruption
面向开放世界：利用深度学习检测和分割孢粉学载玻片上的花粉	Feng, J. T.	PDF	N/A	Addressing the open world: detecting and segmenting pollen on palynological slides with deep learning
伊立替康引起的黏膜炎与杯状细胞相关调控化合物表达的变化有关。	Thorpe, D. W.	PDF	N/A	Irinotecan-induced mucositis is associated with variation in the expression of regulatory compounds associated with goblet cells
通过内在测量操纵环境可供性：来自感觉运动脑动力学的证据	Wang, S.	PDF	N/A	Manipulating Environmental Affordances via Intrinsic Measurement: Evidence from Sensorimotor Brain Dynamics
缺乏ADAP1/Centaurin-α1可改善阿尔茨海默病小鼠模型的认知障碍和神经病理学特征	Szatmari, E. M.	PDF	N/A	Lack of ADAP1/Centaurin-α1 Ameliorates Cognitive Impairment and Neuropathological Hallmarks in a Mouse Model of Alzheimer's Disease
加勒比海八放珊瑚群落：在树木中寻找森林？	Lasker, H. R.	PDF	N/A	Caribbean octocoral communities: finding the forest for the trees?
澳大利亚盐沼蚊（Aedes vigilax）的种群在泛交和暂时稳定的局部遗传结构之间变化。	Schmidt, T. L.	PDF	N/A	Populations of the Australian saltmarsh mosquito Aedes vigilax vary between panmixia and temporally stable local genetic structure
Mumemto：跨泛基因组的高效最大匹配	Shivakumar, V. S.	PDF	N/A	Mumemto: efficient maximal matching across pangenomes
VISTA通过四个氨基酸的细胞内基序诱导肿瘤抑制	Zhao, Y.	PDF	N/A	VISTA-induced tumor suppression by a four amino acid intracellular motif
设计一种专性共生关系，用于基于生物体的生物遏制	Forti, A. M.	PDF	N/A	Design of an exclusive obligate symbiosis for organism-based biological containment
光谱声学对音乐愉悦感的贡献是由自主神经输入动态塑造的。	Cheung, V. K. M.	PDF	N/A	Spectral acoustic contributions to musical pleasure are dynamically shaped by autonomic neural inputs
基于增强条件变分自编码器的神经影像分析规范模型	Ho, M. P.	PDF	N/A	An Enhanced Conditional Variational Autoencoder-Based Normative Model for Neuroimaging Analysis
通过高通量蛋白质-脂质相互作用筛选进行脂质结合探针的合理工程	NISHIMURA, T.	PDF	N/A	Rational engineering of lipid-binding probes via high-throughput protein-lipid interaction screening
印度贾姆谢德布尔地区自由放养犬类种群数量与健康状况的变化与捕捉-绝育-接种-放归计划的关系

BioRxiv 2025-01-04 Papers

标题	作者	PDF链接	代码仓库	Title
全基因组范围内的体内CRISPR筛选揭示GATOR1是MYC驱动淋巴瘤发生中的强效肿瘤抑制因子	Potts, M. A.	PDF	N/A	Genome-wide in vivo CRISPR screens identify GATOR1 as a potent tumor suppressor in MYC-driven lymphomagenesis
多组学图谱辅助发现用于选择性T细胞状态编程的转录因子	Chung, H. K.	PDF	N/A	Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming
刺激的新颖性揭示了视觉皮层调查中的编码多样性	Garrett, M.	PDF	N/A	Stimulus novelty uncovers coding diversity in survey of visual cortex
将多个单细胞多组学样本与Smmit进行整合	Wan, C.	PDF	N/A	Integrating multiple single-cell multi-omics samples with Smmit
遗传和环境对人类免疫细胞表观基因组的独特影响	Wang, W.	PDF	N/A	Genetics and Environment Distinctively Shape the Human Immune Cell Epigenome
中温升期间高山植物Wahlenbergia ceracea耐热性和敏感性的分子特征	Notarnicola, R. F.	PDF	N/A	Molecular signatures of heat tolerance and sensitivity in the alpine plant Wahlenbergia ceracea during moderate warming
与动物相比，植物中物种屏障的快速建立	Monnet, F.	PDF	N/A	Rapid establishment of species barriers in plants compared to animals
空间分辨的动态核极化辅助核磁共振技术揭示了完整活细胞内α-突触核蛋白的构象集合。	Kragelj, J.	PDF	N/A	Spatially resolved DNP-assisted NMR illuminates the conformational ensemble of α-synuclein in intact viable cells.
在选择性注意过程中的神经语音追踪：一项空间逼真的视听研究	Har-shai Yahav, P.	PDF	N/A	Neural Speech-Tracking During Selective Attention: A spatially realistic audiovisual study
评估大型多模态模型在生物医学图像分类中的一次性学习能力和可解释性	Hou, W.	PDF	N/A	Assessing large multimodal models for one-shot learning and interpretability in biomedical image classification
一种新型LAMA2相关肌营养不良症小鼠模型：分子发病机制与临床表型分析	Tan, D.	PDF	N/A	A Novel Mouse Model for LAMA2-Related Muscular Dystrophy: Analysis of Molecular Pathogenesis and Clinical Phenotype
基于表面的纤维束追踪揭示了前额叶皮层中的“是什么”和“在哪里”通路	Bedini, M.	PDF	N/A	Surface-based Tractography uncovers 'What' and 'Where' Pathways in Prefrontal Cortex
冷冻电镜揭示反应性全长人类动力蛋白-1的机械化学循环	Chai, P.	PDF	N/A	Cryo-EM Reveals the Mechanochemical Cycle of Reactive Full-length Human Dynein-1
纳米基序：利用DNA甲基化基序从复杂微生物群落的宏基因组中进行基因组恢复和质粒宿主关联	Heidelbach, S.	PDF	N/A	Nanomotif: Leveraging DNA Methylation Motifs for Genome Recovery and Host Association of Plasmids in Metagenomes from Complex Microbial Communities
miRTarDS：利用Sentence-BERT从预测数据库中高精度精炼蛋白质水平的微RNA靶标相互作用	Chen, B.	PDF	N/A	miRTarDS: High-Accuracy Refining Protein-level MicroRNA Target Interactions from Prediction Databases Using Sentence-BERT
跨组织的性别偏向基因表达揭示了刺鱼鳃中的意外分化	Sylvestre, F.	PDF	N/A	Sex-biased gene expression across tissues reveals unexpected differentiation in the gills of the threespine stickleback
IgStrand：一种用于研究免疫球蛋白组（Ig-Proteomes）和免疫球蛋白相互作用组（Ig-Interactomes）的通用免疫球蛋白折叠（Ig-fold）残基编号方案。	Tawfeeq, C.	PDF	N/A	IgStrand: A universal residue numbering scheme for the Immunoglobulin-fold (Ig-fold) to study Ig-Proteomes and Ig-Interactomes
利用交联剂扩散在藻酸盐水凝胶中模板化刚度梯度	Ostrowski, Z.	PDF	N/A	Leveraging Crosslinker Diffusion to Template Stiffness Gradients in Alginate Hydrogels
解剖学中的保守编码：大脑中的神经元通过其放电序列（spike trains）嵌入其解剖位置的稳健特征。	Tolossa, G. B.	PDF	N/A	A conserved code for anatomy: Neurons throughout the brain embed robust signatures of their anatomical location into spike trains.
单价伪天然产物降解剂通过KLHDC3增强IDO1的天然降解能力。	Hennes, E.	PDF	N/A	Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3
微量元素提高了微生物生长的可重复性	Shimoga Nadig, A.	PDF	N/A	Trace elements increase reproducibility of microbial growth
真实和误导性指令对自闭症谱系中统计学习的影响	Angeletos Chrysaitis, N.	PDF	N/A	Influence of truthful and misleading instructions on statistical learning across the autism spectrum
灵活控制运动单位：运动单位流形的多维性是否是一个充分条件？	Dernoncourt, F.	PDF	N/A	Flexible Control of Motor Units: Is the Multidimensionality of Motor Unit Manifolds a Sufficient Condition?
资源质量对水蚤与两种寄生虫的相互作用具有差异性影响	Fearon, M. L.	PDF	N/A	Resource Quality Differentially Impacts Daphnia Interactions with Two Parasites
单细胞RNA测序揭示了在急性椎间盘损伤反应中，内源性和浸润性细胞类型的细胞功能和成熟度的变化。	Clayton, S. W.	PDF	N/A	Single cell RNA sequencing reveals a shift in cell function and maturation of endogenous and infiltrating cell types in response to acute intervertebral disc injury
青春期前后对促肾上腺皮质激素释放因子受体1的拮抗作用会导致行为可塑性和杏仁核转录组谱的持续变化	Martz, J.	PDF	N/A	Peripubertal antagonism of corticotropin-releasing factor receptor 1 results in sustained changes in behavioral plasticity and the transcriptomic profile of the amygdala
AI驱动的耐碱性蛋白质进化技术应用于大规模生产	Kang, L.	PDF	N/A	AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production
阿尔茨海默病小鼠模型中海马-前额叶神经动力学紊乱与风险决策行为的研究	Kim, E. J.	PDF	N/A	Disruption of hippocampal-prefrontal neural dynamics and risky decision-making in a mouse model of Alzheimer's disease
与糖尿病及糖尿病肾病相关的尿路微生物组：一项系统性综述	Graells, T.	PDF	N/A	The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review
多感官伽马刺激增强成年神经发生并改善唐氏综合症雄性小鼠的认知功能	Islam, M. R.	PDF	N/A	Multisensory gamma stimulation enhances adult neurogenesis and improvescognitive function in male mice with Down Syndrome
高分辨率全基因组图谱揭示扭转绝缘的广泛存在	Hall, P. M.	PDF	N/A	High-Resolution Genome-Wide Maps Reveal Widespread Presence of Torsional Insulation
以下是这段英文的中文翻译：

关于草棉黄素抑制登革热病毒NS5甲基转移酶的机制研究

翻译说明： - "Mechanistic insights" 翻译为“机制研究”或“机制探讨”，表示对某种机制的理解或分析。 - "dengue virus NS5 methyltransferase" 指“登革热病毒NS5甲基转移酶”，是登革热病毒复制过程中的一个关键酶。 - "herbacetin" 是“草棉黄素”，一种天然黄酮类化合物，具有潜在的抗病毒活性。

如果需要进一步调整或补充，请告诉我！ | Bhutkar, M. | PDF | N/A | Mechanistic insights into the inhibition of dengue virus NS5 methyltransferase by herbacetin | | ALDH1亚型特异性抑制剂针对侵袭性乳腺癌亚型中的关键癌性上皮细胞群体 | PEREZ, M. | PDF | N/A | ALDH1 subtype-specific inhibitor targets key cancerous epithelial cell populations in aggressive subtypes of breast cancer | | 快速微流控灌注系统能够控制由Na+/H+交换体NHE1调控的细胞内pH值的动态变化。 | Tran, Q. D. | PDF | N/A | Rapid microfluidic perfusion system enables controlling dynamics of intracellular pH regulated by Na+/H+ exchanger NHE1 | | 发育中的哺乳动物视网膜机械特性的尺度不变性 | Shelton, E. R. | PDF | N/A | Scale invariance of mechanical properties in the developing mammalian retina | | 阿尔茨海默病患者大脑中长链非编码RNA的空间表达 | Ng, B. | PDF | N/A | Spatial Expression of Long Non-Coding RNAs in Human Brains of Alzheimer's Disease | | 上丘（Superior colliculus）在眼跳（saccadic）期间的周围场电位主要表现出对上视野（upper visual field）的视觉感觉偏好。 | Hafed, Z. M. | PDF | N/A | Superior colliculus peri-saccadic field potentials are dominated by a visual sensory preference for the upper visual field | | 改进顶点生物化学实验室并转型为基于课程的本科研究体验：从COVID-19在线教学模式中汲取的经验教训 | Rascon, A. A. | PDF | N/A | Improving the Capstone Biochemistry Lab and Evolution to a Course-Based Undergraduate Research Experience: Lessons Learned from the COVID-19 Online Modality | | 通过体内邻近标记揭示视网膜神经元中的电突触蛋白质组 | Tetenborg, S. | PDF | N/A | Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling | | 使用AlphaFold2预测肽的结构构象 | Ille, A. M. | PDF | N/A | Prediction of peptide structural conformations with AlphaFold2 | | 是什么让人类大脑皮层的锥体神经元在功能上如此复杂 | Aizenbud, I. | PDF | N/A | What makes human cortical pyramidal neurons functionally complex | | 卡西尼：一种用于RNA和蛋白质原位分析的简化且可扩展的方法 | Lapique, N. | PDF | N/A | Cassini: Streamlined and Scalable Method for in situ profiling of RNA and Protein | | 非洲霍乱弧菌分离株的基因组多样性与抗菌素耐药性：PulseNet非洲计划利用纳米孔测序加强基因组监测 | Foster-Nyarko, E. | PDF | N/A | Genomic Diversity and Antimicrobial Resistance of Vibrio cholerae Isolates from Africa: A PulseNet Africa Initiative Using Nanopore Sequencing to Enhance Genomic Surveillance | | DUSP6在转移过程中上调，并影响胰腺癌细胞的迁移和代谢。 | Tannus Ruckert, M. | PDF | N/A | DUSP6 is upregulated in metastasis and influences migration and metabolism in pancreatic cancer cells | | 肝脏微循环的激光散斑对比成像 | Zhukov, O. | PDF | N/A | Laser speckle contrast imaging of hepatic microcirculation | | 人类胰岛素降解酶构象动力学的表征与调控以控制酶活性 | Mancl, J. M. | PDF | N/A | Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity | | 将致癌信号重定向至RNA载体复制以治疗转移性癌症 | Lin, M. Z. | PDF | N/A | Rewiring oncogenic signaling to RNA vector replication for the treatment of metastatic cancer | | 40S核糖体亚基通过一维扩散扫描mRNA以寻找起始密码子。 | Wakabayashi, H. | PDF | N/A | 40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion | | 长读长全基因组测序为研究与原发性脑黑色素真菌病相关的嗜神经性暗色真菌的生物学特性、应激适应机制及毒力提供了新的见解。 | Samaddar, A. | PDF | N/A | Long-read whole-genome sequencing offers novel insights into the biology, stress adaptation, and virulence of neurotropic dematiaceous fungi associated with primary cerebral phaeohyphomycosis | | LCORL和STC2基因变异可增加牛及其他动物的体型和生长速率 | Bai, F. | PDF | N/A | LCORL and STC2 variants increase body size and growth rate in cattle and other animals | | 高质量基因组组装：来自模式豆科植物百脉根（Lotus japonicus）的152种根际共生细菌 | Repolles, A. G. | PDF | N/A | High-quality genome assemblies of 152 root commensal bacteria from the model legume Lotus japonicus | | 神经元中的LAG3促进致病性α-突触核蛋白在神经元之间的传播 | Yang, X. | PDF | N/A | Neuronal LAG3 facilitates pathogenic α-synuclein neuron-to-neuron propagation | | 内源性阿片类镇痛作用的收敛状态控制 | Kimmey, B. A. | PDF | N/A | Convergent state-control of endogenous opioid analgesia | | 马查多-约瑟夫病（Machado-Joseph Disease）患者及临床前模型中的昼夜节律紊乱 | Ribeiro, R. F. | PDF | N/A | Circadian Rhythms are Disrupted in Patients and Preclinical Models of Machado-Joseph Disease | | 在壶菌生命周期中，中心粒和微管细胞骨架的动态重塑 | Long, A. F. | PDF | N/A | Dynamic remodeling of centrioles and the microtubule cytoskeleton in the lifecycle of chytrid fungi | | 在美国东北部通过创建和更新区域最需要保护的物种（RSGCN）清单进行战略保护优先排序 | Starking, M. D. | PDF | N/A | Strategic Conservation Prioritization Through Creating and Updating the Regional Species of Greatest Conservation Need (RSGCN) List in the Northeastern U.S. | | 对模型刺胞动物星虫（Nematostella vectensis）中RNA干扰机制的表征揭示了部分目标基因的沉默，但缺乏小RNA的扩增现象。 | Admoni, Y. | PDF | N/A | Characterization of RNA interference in the model cnidarian Nematostella vectensis reveals partial target silencing but lack of small RNA amplification | | RSPO3在雌激素介导的体脂分布性别差异中的作用：一项基于单细胞数据的研究 | Xu, Q. | PDF | N/A | Role of RSPO3 in Estrogen-mediated Sex Differences in Body Fat Distribution: A Single-cell Data-driven Study | | Semaphorin7A和PD-L1在乳腺退化和乳腺癌期间协同驱动免疫抑制 | Lyons, T. R. | PDF | N/A | Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer | | 高级肝细胞癌的蛋白质组学分析揭示了治疗反应的预测性特征 | Delamarre, A. | PDF | N/A | Proteomic profiling of advanced hepatocellular carcinoma identifies predictive signatures of response to treatments | | 舞蹈：一个开源分析管道和低成本硬件，用于量化果蝇的攻击和求偶行为 | Yadav, R. S. P. | PDF | N/A | DANCE: An open-source analysis pipeline and low-cost hardware to quantify aggression and courtship in Drosophila | | 将神经群体格式化与功能联系起来 | Ruff, D. A. | PDF | N/A | Linking neural population formatting to function | | TSPO-PET显示在多发性硬化症中，被顺磁性边缘病变破坏的白质区域炎症水平更高。 | Tozlu, C. | PDF | N/A | TSPO-PET Reveals Higher Inflammation in White Matter Disrupted by Paramagnetic Rim Lesions in Multiple Sclerosis | | 微生物在分层湖泊的氧化还原过渡带中的氮去除与再循环及其与硫的耦合 | Tischer, J. | PDF | N/A | Microbial nitrogen removal versus recycling in the redox transition zone of a meromictic lake and its coupling to sulfur | | 新生链被核糖体相关质量控制复合物移除的机制 | Li, W. | PDF | N/A | Mechanism of nascent chain removal by the Ribosome-associated Quality Control complex | | RBPscan：一种用于分析RNA结合蛋白相互作用的定量体内工具 | Kretov, D. A. | PDF | N/A | RBPscan: A Quantitative, In Vivo Tool for Profiling RNA-Binding Protein Interactions | | 基于原子力显微镜（AFM）的单细胞水平下造血干细胞微环境中物理相互作用的纳米尺度表征 | Kubiak, A. J. | PDF | N/A | AFM-based nanoscale characterization of physical interaction within hematopoietic stem cells niche at single-cell level | | ORP2在MASH期间调节肝细胞中的游离胆固醇积累 | Wu, J. | PDF | N/A | ORP2 regulates free cholesterol accumulation in hepatocytes during MASH | | 分支与线性F-肌动蛋白网络调控对齐胶原纤维上的定向迁移转换行为 | Foroozandehfar, A. | PDF | N/A | Branched and Linear F-actin Networks Control Directional Migration Switching Behavior on Aligned Collagen Fibrils | | GRF转录因子的WRC结构域。结构与DNA识别。 | Biglione, F. A. | PDF | N/A | The WRC domain of GRF transcription factors. Structure and DNA recognition | | 氢键有机框架纳米转换器实现帕金森病大鼠的声光遗传学治疗 | Wang, W. | PDF | N/A | Hydrogen-bonded organic framework nanotransducers enabled sono-optogenetics for Parkinsonian rats | | 协同网络药理学与泛癌分析在中药重定位用于肿瘤治疗中的应用 | Yang, D. | PDF | N/A | Synergizing Network Pharmacology and Pan-Cancer Analysis in TCM Repositioning for Tumor Therapy | | 基于熵的模型选择方法及其在单细胞时间戳快照数据中的应用 | Stewart, W. C. | PDF | N/A | An Entropy-Based Approach to Model Selection with Application to Single-Cell Time-Stamped Snapshot Data | | 通过腹侧中线间质通道注射实现高效器官靶向运输：间质研究的新进展 | Song, X. | PDF | N/A | Highly efficient organ-targeting transport through the ventral midline interstitial channels injection: a new development of interstitium | | 细胞间信号传导稳定了单细胞水平的表型转变，并加速了异质性癌细胞群体平衡的重建。 | Lopez, D. | PDF | N/A | Intercellular signaling stabilizes single-cell level phenotypic transitions and accelerates the reestablishment of equilibrium of heterogeneous cancer cell populations | | 猕猴视觉皮层中自然纹理的对比不变性表征的出现 | Lee, G. M. | PDF | N/A | Emergence of a contrast-invariant representation of naturalistic texture in macaque visual cortex | | 抗抑郁药物通过重塑细胞外基质促进类似发育的可塑性 | Nguyen, P. T. | PDF | N/A | Antidepressants promote developmental-like plasticity through remodeling of extracellular matrix | | 短期街机动作视频游戏增强工作记忆精确性 | Asgari, A. | PDF | N/A | Short-Term Arcade-Action Video Gaming Enhances Working Memory Precision | | 早期噪音暴露与内侧橄榄耳蜗强度变化对听觉通路发育的影响 | Castagna, V. C. | PDF | N/A | Early Noise Exposure and Changes in Medial Olivocochlear Strength Alters Auditory Pathway Development | | 使用药物敏感酵母的mTOR抑制剂发现系统 | Breen, A. K. | PDF | N/A | An mTOR Inhibitor Discovery System Using Drug-Sensitized Yeast | | 开发一个模型系统以维持离体叶绿体功能 | Mohagheghi, M. V. | PDF | N/A | Developing a model system to sustain ex vivo chloroplast function | | 一种新型银钌基抗菌剂通过氧化应激诱导的大分子损伤杀死革兰氏阴性菌 | Tawiah, P. O. | PDF | N/A | A Novel Silver-Ruthenium-Based Antimicrobial Kills Gram-Negative Bacteria Through Oxidative Stress-Induced Macromolecular Damage | | 调控lncRNA malat1/Egr1轴通过Wnt、Notch和TGF-β信号通路：视网膜再生的关键机制

这段文字描述了一个科学研究的主题，涉及到长链非编码RNA（lncRNA）malat1与早期生长反应蛋白1（Egr1）之间的相互作用，以及Wnt、Notch和TGF-β这三种重要的细胞信号通路如何调控这一相互作用。这一调控机制被认为是视网膜再生过程中的一个关键环节。视网膜再生是指视网膜在受到损伤后，通过细胞增殖和分化等过程恢复其结构和功能的能力。这一研究可能有助于理解视网膜疾病的治疗和修复机制。 | Premraj, S. | PDF | N/A | Regulation of the lncRNA malat1/Egr1 Axis by Wnt, Notch and TGF-β signaling: A Key Mechanism in Retina Regeneration | | 布拉氏短螺旋体新型外膜蛋白的鉴定与特性分析 | Panda, A. | PDF | N/A | Identification and Characterization of Novel Outer Membrane Proteins of Brachyspira pilosicoli | | 开发质子密度脂肪分数微型MRI技术，用于无创定量评估小鼠模型中骨髓随年龄和辐射的变化 | Ghimire, H. M. | PDF | N/A | Development of Proton Density Fat Fraction Micro-MRI for Non-Invasive Quantitative Assessment of Bone Marrow Changes with Age and Radiation in Mouse Models | | 海草阿拉伯半乳糖蛋白：它们对适应海洋环境重要吗？ | Pfeifer, L. | PDF | N/A | Seagrass arabinogalactan-proteins: Are they important for adaptation to the marine environment? | | T淋巴细胞特异性删除SHP1和SHP2促进CD4+ T细胞的活化诱导细胞死亡并损害抗肿瘤反应 | Foster, C. J. | PDF | N/A | T Lymphocyte-Specific Deletion of SHP1 and SHP2 Promotes Activation-Induced Cell Death of CD4+ T Cells and Impairs Antitumor Response | | 使用聚焦离子束-扫描电子显微镜对伯纳特立克次体感染进行三维定量表征 | Botting, J. | PDF | N/A | Three-dimensional quantitative characterization of Coxiella burnetii infection using focused ion beam-scanning electron microscopy | | 通过注射重组EtpA糖蛋白进行肠外疫苗接种可抑制肠毒素性大肠杆菌的定植。 | Vickers, T. J. | PDF | N/A | Parenteral Vaccination with recombinant EtpA glycoprotein impairs enterotoxigenic E. coli colonization | | 手工奶酪加工环境中持久性和非持久性单核细胞增生李斯特菌的生物膜形成能力、消毒剂耐受性及遗传特征 | Aboagye, E. F. | PDF | N/A | Biofilm Forming Capacity, Sanitizer Tolerance and Genetic Characterization of Persistent and Non-Persistent Listeria monocytogenes from Artisanal Cheese Processing Environments | | 由寄生生活方式驱动的剧烈基因组缩减：可能由甲藻宿主的两株完整的内共生细菌基因组 | Nakayama, T. | PDF | N/A | Drastic genome reduction driven by parasitic lifestyle: Two complete genomes of endosymbiotic bacteria possibly hosted by a dinoflagellate | | RNA变性是环状RNA分离的基础 | Jiang, Y. | PDF | N/A | RNA denaturation underlies circular RNA separation | | 热力学不确定性关系限制了信息通过细胞信号系统的传输。 | Verma, S. | PDF | N/A | Thermodynamic uncertainty relation constraints information transmission through cell signaling systems | | 随着阿尔茨海默病进展检测到的脑-脑室耦合模式变化通过功能磁共振成像（fMRI）发现 | Campo, F. F. | PDF | N/A | Altered brain-ventricle coupling modes over Alzheimer's disease progression detected with fMRI | | 零相位延迟连接性提高了功能连接性指标的可靠性、与结构的一致性以及预测能力。 | Mehra, C. | PDF | N/A | Zero-phase-delay connectivity increases the reliability, concordance with structure, and prognostic ability of functional connectivity metrics | | 简单生长条件提高新型隐球菌中目标基因删除的效率 | Watson, R. G. | PDF | N/A | Simple Growth Conditions Improve Targeted Gene Deletion in Cryptococcus neoformans | | 沃尔巴克氏体及其pWCP质粒在库蚊发育过程中表现出不同的动态变化。 | Brunner, A. S. | PDF | N/A | Wolbachia and its pWCP plasmid show differential dynamics during the development of Culex mosquitoes | | 小脂蛋白LptM介导的脂多糖转运体组装的结构基础 | Miyazaki, R. | PDF | N/A | Structural basis of lipopolysaccharide translocon assembly mediated by the small lipoprotein LptM | | 胰岛素中的变构残基动力学：温度诱导从双六聚体向六聚体集体运动的转变 | Ayan, E. | PDF | N/A | Allosteric Residue Dynamics in Insulin: Temperature Induces Shift from Dihexamer to Hexamer Collective Motion | | 高压高尔基神经元染色用于X射线全脑成像 | Tang, Q. | PDF | N/A | High-pressure Golgi neuronal staining for X-ray whole-brain imaging | | 非小细胞肺癌原位微环境中的TCR克隆性和TCR克隆扩增 | Yu, H. | PDF | N/A | TCR clonality and TCR clonal expansion in the in situ microenvironment of non-small cell lung cancer | | 探索阿尔茨海默病严重程度中的社会认知衰退：来自比较分析的见解 | Martins, G. C. | PDF | N/A | EXPLORING SOCIAL COGNITION DECLINE ACROSS ALZHEIMER'S DISEASE SEVERITY: INSIGHTS FROM A COMPARATIVE ANALYSIS | | 通过对Candidozyma auris进行体外进化实验，使其产生对卡泊芬净的抗药性，这一过程主要通过FKS1热点I区域的突变实现。研究发现，这种抗药性的获得导致了适度的适应性代价，但并未降低其致病性。 | Ross, Z. K. | PDF | N/A | In vitro evolution of caspofungin resistance in Candidozyma auris via FKS1 hotspot I mutations results in moderate fitness trade-offs but no reduction in virulence | | 肺泡代谢物的可用性促进了铜绿假单胞菌在急性损伤肺部的继发感染。 | Baker, J. M. | PDF | N/A | Alveolar metabolite availability facilitates secondary infection by Pseudomonas aeruginosa in acutely injured lungs | | 探索新型拟杆菌门菌株：功能多样性及益生特性 | Ladewig, L. | PDF | N/A | Exploring new Bacteroidota strains: Functional Diversity and Probiotic Characteristics | | 将这段英文翻译成中文为：

全球表达谱：肠出血性大肠杆菌O157:H7在小鼠巨噬细胞吞噬体中的表达情况

II类醛缩酶/内收蛋白结构域内蛋白质相互作用的分子和进化决定因素

翻译说明： - "Molecular and evolutionary determinants" 翻译为 "分子和进化决定因素"。 - "protein interaction" 翻译为 "蛋白质相互作用"。 - "within a class II aldolase/Adducin domain" 翻译为 "在II类醛缩酶/内收蛋白结构域内"。

希望这个翻译对你有帮助！ | Seheon, M. E. | PDF | N/A | Molecular and evolutionary determinants for protein interaction within a class II aldolase/Adducin domain | | 映射NMD脱帽复合物内的相互作用揭示了Upf1如何将Dcp2招募到mRNA靶标上 | RUIZ GUTIERREZ, N. | PDF | N/A | Mapping interactions within the NMD decapping complex reveals how Upf1 recruits Dcp2 onto mRNA targets | | HeteroRepur：利用异构图神经网络高效建模抑郁症药物再利用的异质疾病图 | Lin, K.-H. | PDF | N/A | HeteroRepur: Efficient Modeling of Heterogeneous Disease Graph for Depression Drug Repurposing using Heterogeneous Graph Neural Networks | | 使用纳米聚合物靶向和治疗三阴性乳腺癌的药物耐药性：负载多柔比星和抗miR-21的A6肽-PLGA-PEG纳米颗粒在体外和体内模型中的疗效。 | Ibrahim, Z. | PDF | N/A | Targeting and combating drug resistance in triple-negative breast cancer using nano polymer: Efficacy of A6 peptide-PLGA-PEG nanoparticle loaded with doxorubicin and anti-miR-21 in in vitro and vivo model. | | 单分子成像技术在体内观察RecB蛋白的动态，揭示了大肠杆菌中DNA双链断裂修复的过程。 | Thedie, D. | PDF | N/A | Single molecule imaging of RecB in vivo reveals dynamics of DNA Double Strand Break repair in Escherichia coli | | 细菌Vibrio atlanticus的饥饿状态促进了其对甲藻Alexandrium pacificum的群体攻击行为。 | Rolland, J. L. | PDF | N/A | Starvation of the bacteria Vibrio atlanticus promotes lightning group-attacks on the dinoflagellate Alexandrium pacificum | | 雌激素受体调控结构域的结构演化 | McDougal, D. P. | PDF | N/A | Structural evolution of the estrogen receptor regulatory domain | | 自然变异影响拟南芥近着丝粒区域的减数分裂交叉频率和分离扭曲现象 | Gorringe, N. | PDF | N/A | Natural variation modifies centromere proximal meiotic crossover frequency and segregation distortion in Arabidopsis thaliana | | ModiDeC：一种用于直接纳米孔测序的多RNA修饰分类器 | Alagna, N. | PDF | N/A | ModiDeC: a multi-RNA modification classifier for direct nanopore sequencing | | 雌性埃及伊蚊（Aedes aegypti）吸血后神经肽释放和活动的动态变化 | Sajadi, F. | PDF | N/A | Dynamics of neuropeptide release and activity post-bloodmeal in the female mosquito, Aedes aegypti | | 基于合成数据训练的机器学习分割工具，用于追踪细胞骨架的聚合与解聚过程。 | Elangovan, K. | PDF | N/A | Machine learning segmentation tool trained on synthetic data for tracking cytoskeleton polymerisation and depolymerisation | | 下一代ACINUS介导的替代剪接机制图谱及其在拟南芥中通过O-糖基化调控的研究 | Shrestha, R. | PDF | N/A | Next-Generation Mapping of the ACINUS-Mediated Alternative Splicing Machinery and Its Regulation by O-glycosylation in Arabidopsis | | 豌豆保护伙伴：芽孢杆菌和假单胞菌联手对抗豌豆霜霉病 | Okechukwu, E. C. | PDF | N/A | Pea-Saving Partners: Bacillus and Pseudomonas combat downy mildew in pea crops | | 工程化活体胶水用于自主检测和按需治疗炎症性肠病 | An, B. | PDF | N/A | Engineered Living Glues for Autonomous Detection and On-Demand Treatment of Inflammatory Bowel Disease | | 单核转录组学揭示了裸盖菇素对基因表达的时间依赖性和细胞类型特异性影响。 | Liao, C. | PDF | N/A | Single-nucleus transcriptomics reveals time-dependent and cell-type-specific effects of psilocybin on gene expression | | 结构基础：经典抗原位点I抗体131-2a对呼吸道合胞病毒F蛋白的融合后特异性结合 | Peng, W. | PDF | N/A | Structural basis for postfusion-specific binding to Respiratory Syncytial Virus F protein by the canonical antigenic site I antibody 131-2a | | LAG3+ CD8+ T细胞亚群增强双特异性抗体武装的活化T细胞对激素受体阳性乳腺癌的细胞毒性 | Barnes, R. W. | PDF | N/A | LAG3+ CD8+ T cell Subset Boosts Bispecific Antibody Armed Activated T Cell Cytotoxicity Directed at Hormone Receptor+ Breast Cancers | | 与全血中中性粒细胞胞外陷阱（NET）形成相关的染色质变化反映了复杂的免疫信号传导 | Cayford, J. | PDF | N/A | Chromatin Changes Associated with Neutrophil Extracellular Trap (NET) Formation in Whole Blood Reflect Complex Immune Signaling | | 噬菌体Mu利用滑动夹进行晚期基因转录 | Ho, K. | PDF | N/A | Phage Mu Utilizes the Sliding Clamp for Late Gene Transcription | | 流感病毒微型病毒RNA激活RIG-I的两步机制 | Pitre, E. | PDF | N/A | A two-step mechanism for RIG-I activation by influenza virus mini viral RNAs | | BICD2是一种中心粒蛋白，它控制着母-子中心粒的结合以及复制的许可。 | Montes-Ruiz, L. | PDF | N/A | BICD2 is a centriolar protein that controls mother-daughter centriole engagement and the licensing of duplication | | 非对比显微CT分析揭示冷暴露对肥胖脂肪组织的性别特异性影响 | Eades, A. E. | PDF | N/A | Non-Contrast microCT Analysis of Obese Adipose in Response to Cold-Exposure Reveals Sex-Specific Alterations | | 马蹄蟹、蝎子、蜘蛛及其他螯肢动物物种中金属硫蛋白的进化历史。 | Palacios, O. | PDF | N/A | THE EVOLUTIONARY HISTORY OF METALLOTHIONEINS IN HORSESHOE CRABS, SCORPIONS, SPIDERS AND OTHER CHELICERATE SPECIES. | | 三方环逆转抗生素耐药性 | Chowdhury, F. R. | PDF | N/A | Tripartite loops reverse antibiotic resistance | | 高效Kemp消除酶通过完整计算设计 | Listov, D. | PDF | N/A | High-efficiency Kemp eliminases by complete computational design | | 关于全反式视黄酸在近视形成中的运输研究 | Chatterjee, S. | PDF | N/A | Studies of all-trans retinoic acid transport in myopigenesis | | 基于机制的硒氰酸盐对组蛋白去乙酰化酶6的抑制受氧化还原调控 | Goulart Stollmaier, J. | PDF | N/A | Mechanism-Based Inhibition of Histone Deacetylase 6 by a Selenocyanate is Subject to Redox Modulation | | 单细胞多组学数据整合与生成：scPairing | Niu, J. | PDF | N/A | Single-cell multiomics data integration and generation with scPairing | | 单细胞转录组学中的空间差异性分析 | Shi, Q. | PDF | N/A | Spatial dissimilarity analysis in single cell transcriptomics | | 湿度驱动的ABA（脱落酸）消耗决定了植物与病原体对叶片水分的竞争。 | Yasuda, S. | PDF | N/A | Humidity-driven ABA depletion determines plant-pathogen competition for leaf water | | 一个数据驱动的建模框架，用于将基因型映射到合成微生物群落功能 | Qian, Y. | PDF | N/A | A data-driven modeling framework for mapping genotypes to synthetic microbial community functions | | 在TSA数据库中发现的高度多样化的mesnidoviruses，特别是在蜘蛛中。 | Xie, J. | PDF | N/A | Highly divergent mesnidoviruses found in TSA database, especially in spiders | | c-di-GMP 是大肠杆菌群游运动所必需的。 | Hwang, Y. | PDF | N/A | c-di-GMP is required for swarming motility in E. coli | | 十种细菌占据了细菌学文献的一半，使得大多数细菌种类尚未被研究。 | Jensen, P. A. | PDF | N/A | Ten species comprise half of the bacteriology literature, leaving most species unstudied | | 病原共生体触发的上皮细胞IDO1诱导驱动炎症性肠病的区域易感性 | Spencer, P. N. | PDF | N/A | Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease | | 形态素在动态组织中的模式形成 | Plum, A. M. | PDF | N/A | Morphogen Patterning in Dynamic Tissues |

BioRxiv 2025-01-03 Papers

标题	作者	PDF链接	代码仓库	Title
基础模型实现了基于质谱的蛋白质组学的可解释、开放和容错搜索	Altenburg, T.	PDF	N/A	Foundation Model Enables Interpretable Open and Error-Tolerant Searching for Mass Spectrometry-Based Proteomics
可擦除的海马神经特征预测记忆辨别	Kinsky, N. R.	PDF	N/A	Erasable Hippocampal Neural Signatures Predict Memory Discrimination
特定微环境巨噬细胞缺失促进皮肤毛细血管老化	Mesa, K. R.	PDF	N/A	Niche-specific macrophage loss promotes skin capillary aging
长期暴露于乙醇会导致纹状体价值计算的性别依赖性损害	Cheng, Y.	PDF	N/A	Chronic Ethanol Exposure Produces Sex-Dependent Impairments in Value Computations in the Striatum
微血管结构变异解释了功能性磁共振成像（fMRI）功能连接性中的差异	Gaudreault, F.	PDF	N/A	Microvascular structure variability explains variance in fMRI functional connectivity
海马体中的小胶质细胞老化通过中间状态推进，这些状态驱动了细胞的激活和认知功能的下降。	Shea, J. M.	PDF	N/A	Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline
比较单细胞转录爆发分析揭示了基因组组织在新生转录起源中的作用	Lee, U.	PDF	N/A	Comparative Single Cell Analysis of Transcriptional Bursting Reveals the Role of Genome Organization on de novo Transcript Origination
累积的储备阻碍了与年龄相关的神经补偿在噪声中语音感知中的作用。	Zhang, L.	PDF	N/A	Accumulated reserves hold back age-related neural compensation in speech-in-noise perception
健康老年人中循环血小板对神经血管功能的直接控制	Rossetti, G. M. K.	PDF	N/A	Direct control of neurovascular function by circulating platelets in healthy older adults
脂质代谢重编程驱动甘油三酯储存，并导致内分泌耐药乳腺癌细胞对FASN抑制的敏感性不同。	Ward, A. V.	PDF	N/A	Lipid metabolic reprogramming drives triglyceride storage and variable sensitivity to FASN inhibition in endocrine-resistant breast cancer cells
通过细菌NLR相关蛋白检测噬菌体是由DnaJ介导的。	Conte, A. N.	PDF	N/A	Phage detection by a bacterial NLR-related protein is mediated by DnaJ
区分混合人群中祖先选择性交配的机制与结果	Massey, D. J.	PDF	N/A	Differentiating mechanism from outcome for ancestry-assortative mating in admixed human populations
一种理解抑郁症中基于努力的决策的计算方法	Valton, V.	PDF	N/A	A computational approach to understanding effort-based decision-making in depression
APP β-CTF 触发细胞自主的突触毒性，独立于 Aβ。	Luo, M.	PDF	N/A	APP β-CTF triggers cell-autonomous synaptic toxicity independent of Aβ
系统性地调查和鉴定人类肠道微生物组中的细菌素	Zhang, D.	PDF	N/A	Systematically investigating and identifying bacteriocins in the human gut microbiome
以下是将这段英文翻译成中文的结果：

一种用于生物医学文本上下文分类的开集半监督多任务学习框架

翻译说明： - "Open-Set" 翻译为 "开集"，表示模型能够处理已知类别和未知类别。 - "Semi-Supervised" 翻译为 "半监督"，表示模型结合了有标签和无标签数据进行训练。 - "Multi-Task Learning" 翻译为 "多任务学习"，表示模型同时学习多个相关任务。 - "Context Classification" 翻译为 "上下文分类"，表示对文本上下文进行分类的任务。 - "Biomedical Texts" 翻译为 "生物医学文本"，指与生物医学领域相关的文本数据。

B群链球菌中乙二醛酶A的鉴定及其对甲基乙二醛耐受性和毒力的贡献

翻译说明： - "Identification" 翻译为“鉴定”。 - "Glyoxalase A" 是乙二醛酶A，一种酶的名称。 - "Group B Streptococcus" 是B群链球菌，一种常见的病原菌。 - "contribution to" 翻译为“对……的贡献”。 - "methylglyoxal tolerance" 是甲基乙二醛耐受性，指细菌对甲基乙二醛这种有毒代谢产物的耐受能力。 - "virulence" 是毒力，指病原菌的致病能力。

Xenosiderophore转运蛋白基因表达和分支特异性丝状化在Candida auris对青鳉鱼感染中的作用

翻译说明： - Xenosiderophore transporter gene expression：Xenosiderophore转运蛋白基因表达 - clade-specific filamentation：分支特异性丝状化 - Candida auris：耳念珠菌（一种真菌病原体） - killifish：青鳉鱼（一种常用于研究的模式生物） - infection：感染

来自模式豆科植物百脉根（Lotus japonicus）的152种根际共生细菌的完整基因组。

翻译说明： 1. "Complete genomes" 翻译为 "完整基因组" 2. "152 root commensal bacteria" 翻译为 "152种根际共生细菌" 3. "from the model legume Lotus japonicus" 翻译为 "来自模式豆科植物百脉根"

其中： - "commensal" 在生物学中通常指共生关系 - "model legume" 指的是被广泛用作研究对象的模式豆科植物 - "Lotus japonicus" 是百脉根的拉丁学名，是一种重要的豆科模式植物

这个翻译准确地传达了原文的科学含义，同时保持了专业术语的准确性。 | Repolles, A. G. | PDF | N/A | Complete genomes of 152 root commensal bacteria from the model legume Lotus japonicus | | 利用流体动力学实现干细胞球体高效生产具有特定货物谱的细胞外囊泡 | Lenoir, S. | PDF | N/A | Harnessing hydrodynamics for high-yield production of extracellular vesicles from stem cells spheroids with specific cargo profiling | | 空间转录组数据分析中分割错误的影响。 | Mitchel, J. | PDF | N/A | Impact of Segmentation Errors in Analysis of Spatial Transcriptomics Data. | | 放线菌噬菌体内含肽：宿主多样性、局部传播与非典型结构 | Gosselin, S. P. | PDF | N/A | Actinobacteriophage Inteins: Host Diversity, Local Dissemination, and Non-Canonical Architecture | | 从生物聚合物的DEER数据中多模态距离分布的局部重建 | Tsay, K. | PDF | N/A | Localized Reconstruction of Multimodal Distance Distribution from DEER Data of Biopolymers | | 偏振光片显微镜和断层扫描技术（PLμTo）用于基于流动的三维微载体间充质干细胞培养成像 | Benavides, O. R. | PDF | N/A | Polarization light-sheet microscopy and tomography (PLμTo) for flow-based imaging of 3D microcarrier mesenchymal stem cell culture | | 在青蒿素部分耐药性的背景下，鉴定下一代抗疟疾三氧杂环己烷化合物 | Klope, M. T. | PDF | N/A | Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance | | 移植免疫抑制疗法会引起淋巴结功能的独特变化，并重塑肠道免疫稳态。 | Wu, L. | PDF | N/A | Transplant immunosuppressant therapies induce unique functional changes in lymph node and re-shape gut immune homeostasis | | 草原管理实践影响着生物多样性、生产力以及地表与大气的相互作用。 | Wang, R. | PDF | N/A | Prairie management practices influence biodiversity, productivity and surface-atmosphere feedbacks | | 解开巨型多样膜翅目昆虫表型组的进化动态 | Sasso Porto, D. | PDF | N/A | Untangling the Evolutionary Dynamics of the Phenome in Megadiverse Hymenoptera | | 在保护性放牧中，当马蝇存在且温度较高时，重新野化的高地牛可能不会更多地梳理毛发。 | Kim, J. | PDF | N/A | Rewilded Highland Cattle in conservation grazing may not groom more when horseflies are present and temperature is higher | | 古代DNA揭示了公元前5千年喀尔巴阡盆地多样化的社区组织 | Szecsenyi-Nagy, A. | PDF | N/A | Ancient DNA reveals diverse community organizations in the 5th millennium BCE Carpathian Basin | | 气候变化情景下中国黄花菜生境适宜性的时空动态 | Yang, L. | PDF | N/A | Spatiotemporal dynamics of Hemerocallis citrina habitat suitability in China under climate change scenarios | | 重新审视肿瘤突变负荷的临界值：免疫治疗中的多研究可重复性 | Jaljuli, I. | PDF | N/A | Revisiting Tumor Mutational Burden Cutoff: Multi-Study Replicability in Immunotherapy | | 估计狐猴（Daubentonia madagascariensis）适应度效应的分布，考虑种群历史以及突变和重组率的异质性。 | Soni, V. | PDF | N/A | Estimating the distribution of fitness effects in aye-ayes (Daubentonia madagascariensis),accounting for population history as well as mutation and recombination rate heterogeneity | | AncestryHub：一个用于本地祖先分析的网络服务器 | Jiang, S. | PDF | N/A | AncestryHub: A web server for local ancestry analysis | | 高分辨率数字解构脑肿瘤与深度多模态自编码器 | Sun, J. | PDF | N/A | High-resolution digital dissociation of brain tumors with deep multimodal autoencoder | | 提升乳腺癌分类：使用堆叠卷积神经网络进行全切片图像分析 | Mujawar, T. s. | PDF | N/A | Enhancing Breast Cancer Classification with Stacked Convolutional Neural Networks for Whole-Slide Image Analysis | | 量化细胞形状——从闵可夫斯基张量到p-atic序 | Happel, L. | PDF | N/A | Quantifying the shape of cells - from Minkowski tensors to p-atic order | | 揭示体内光合系统I光捕获天线的多样性 | Zhang, X. | PDF | N/A | Revealing the diversity of light-harvesting antenna of in vivo photosystem I | | 乳酸化促进核苷酸生物合成，并有助于H3K27M突变胶质瘤中肿瘤增殖的氘代谢成像 | Batsios, G. | PDF | N/A | Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in H3K27M-mutant gliomas | | 1,3-和1,4-连接的多糖在肠道细胞中的摄取依赖于网格蛋白/动力蛋白1/Rab5依赖的内吞作用 | Liao, W. | PDF | N/A | 1,3- and 1,4-linked Polysaccharides Uptake in Intestinal Cells Relies on Clathrin/Dynamin 1/Rab5-dependent Endocytosis | | 铁元素的保留与局部共生效应的权衡相结合，赋予了大豆对铁缺乏和干旱双重胁迫的耐受性。 | Hasan, M. R. | PDF | N/A | Iron retention coupled with trade-offs in localized symbiotic effects confers tolerance to combined iron deficiency and drought in soybean | | Galphimia glauca的网络生药学：绘制一种传统墨西哥药用植物的分子图谱

这段文字可以翻译为：
Galphimia glauca的网络生药学：绘制一种传统墨西哥药用植物的分子图谱

其中：
- Network Pharmacognosy 指的是通过网络药理学的方法研究药用植物。
- Galphimia glauca 是一种植物，中文通常称为“光滑金雀花”或“光滑金雀儿”。
- Mapping the Molecular Landscape 表示绘制其分子层面的图谱或研究其分子特征。
- Traditional Mexican Medicinal Plant 指的是这种植物在墨西哥传统医学中的应用。

对紫黑粉菌复合体（Microbotryum violaceum）中三个成员生命周期依赖的A到I RNA编辑的比较分析

在这段翻译中，"Ultraviolet B" 被翻译为 "紫外线B"，"Induces" 翻译为 "诱导"，"Cutaneous Lupus Erythematosus" 翻译为 "皮肤红斑狼疮"，"by Triggering" 翻译为 "通过触发"，"a Ribotoxic-Stress-Response-Dependent" 翻译为 "核糖体应激反应依赖性"，"MIF-p38 feedback loop" 翻译为 "MIF-p38反馈环路"，"in Keratinocytes" 翻译为 "在角质形成细胞中"。整体翻译保持了原文的科学性和准确性，同时使中文读者能够清晰理解研究的主要内容。 | Guo, C. | PDF | N/A | Ultraviolet B Induces Cutaneous Lupus Erythematosus by Triggering a Ribotoxic-Stress-Response-Dependent MIF-p38 Feedback Loop in Keratinocytes | | MAIT细胞缺乏加剧了P301S人类tau转基因小鼠的神经炎症 | Zhang, Y. | PDF | N/A | MAIT cell deficiency exacerbates neuroinflammation in P301S human tau transgenic mice | | 蛋白质翻译起始机制是开发针对人畜共患病原体隐孢子虫（Cryptosporidium parvum）的快速杀灭疗法的潜在靶点。 | Li, M. | PDF | N/A | The protein translation initiation machinery is targetable for developing fast-killing therapeutics against the zoonotic Cryptosporidium parvum | | 调节磷脂酰肌醇-(4,5)-二磷酸和活性Rho1p的水平及分布对于白色念珠菌的正确时空细胞分裂和棘白菌素反应至关重要 | Badrane, H. | PDF | N/A | Regulation of Phosphatidylinositol-(4,5)-bisphosphate and Active-Rho1p Levels and Distribution is Crucial for Correct Spatio-temporal Cytokinesis and Echinocandin Responses in Candida albicans | | 腹部脓肿中常见细菌对低剂量光动力疗法的敏感性：亚甲蓝浓度、光通量率和光通量的影响 | Hawryluk, D. S. | PDF | N/A | Susceptibility of bacterial species commonly found in abdominal abscesses to low-dose photodynamic therapy: Effects of methylene blue concentration, fluence rate, and fluence | | 一个可解释的人工智能框架揭示了与结核分枝杆菌耐药性相关的突变。 | Zhang, G. | PDF | N/A | An explainable artificial intelligence framework reveals mutations associated with drug resistance in Mycobacterium tuberculosis | | 微生物硫氰酸盐生物降解中羰基硫化物和氰酸盐途径的稳定同位素探测 | Ling, Y.-C. | PDF | N/A | Stable isotope probing of carbonyl sulfide and cyanate pathways in microbial thiocyanate biodegradation | | 7-脱氮-7-氟-2'-C-甲基腺苷在体外和体内对多种冠状病毒的广谱抗病毒效果 | Chaves, I. d. M. | PDF | N/A | Broad-Spectrum Antiviral Efficacy of 7-Deaza-7-Fluoro-2'-C-Methyladenosine Against Multiple Coronaviruses In Vitro and In Vivo | | 全基因组分析揭示了谷氨酸棒杆菌中DtxR和HrrA调控子的新靶点，以及铁和血红素调控网络之间的高度互连性。 | Krüger, A. | PDF | N/A | Genome-wide analysis of DtxR and HrrA regulons reveals novel targets and a high level of interconnectivity between iron and heme regulatory networks in Corynebacterium glutamicum | | 淋球菌β-内酰胺酶质粒的起源与进化及其对公共卫生的影响 | Elsener, T. A. | PDF | N/A | The origin and evolution of the gonococcal beta-lactamase plasmid, and implications for public health | | 在疱疹病毒感染期间，细胞核会软化。 | Tervonen, A. | PDF | N/A | Nucleus softens during herpesvirus infection | | 一种新型XACT长链非编码RNA转录本，其功能超越X染色体失活。 | Zhang, P. | PDF | N/A | A Novel XACT lncRNA Transcript with Functions Transcending X-Chromosome Inactivation. | | 阐明小鼠模型中中央核肌病的分子景观：一项整合多组学与网络分析的研究

在这项研究中，我们通过整合多组学数据和网络分析方法，深入探讨了小鼠模型中中央核肌病（centronuclear myopathies, CNM）的分子机制。中央核肌病是一组罕见的遗传性肌肉疾病，其特征是肌纤维中央核的异常分布。为了揭示其潜在的分子病理机制，我们采用了转录组学、蛋白质组学和代谢组学等多组学技术，结合生物信息学网络分析，系统地描绘了CNM的分子景观。研究结果不仅揭示了与疾病相关的关键分子通路和调控网络，还为未来开发潜在的治疗靶点提供了新的见解。 | Simon, A. | PDF | N/A | Elucidating the molecular landscape of centronuclear myopathies in mouse models: an integrative multi-omics and network analysis | | IMMUcan项目中的大规模癌症组织研究的多模态图像分析 | Schulz, D. | PDF | N/A | Multi-modal image analysis for large scale cancer tissue studies within IMMUcan | | ABA诱导的MYB转录模块调控鹰嘴豆外皮层的分化轨迹 | Jo, L. | PDF | N/A | ABA-induced MYB transcriptional module regulates the differentiation trajectory of chickpea exodermis | | 四种新发布木薯品种在休耕地上两个种植季节的表现 | Ossai, C. O. | PDF | N/A | PERFORMANCE OF FOUR NEWLY RELEASED CASSAVA VARIETIES IN A FALLOWED LAND OVER TWO FARMING SEASONS | | 从Alstonia boonei和Terminalia catappa绿色合成的银和铁纳米颗粒作为小鼠模型中的抗疟剂 | Abuh, O. O. | PDF | N/A | Green-synthesized silver and iron nanoparticles from Alstonia boonei and Terminalia catappa as antimalarial agent in mice model | | GABAB受体介导的腹内侧缰核谷氨酸能传递在GABA能和谷氨酸能脚间核神经元中的增强作用。 | Stinson, H. E. | PDF | N/A | GABAB receptor-mediated potentiation of ventral medial habenula glutamatergic transmission in GABAergic and glutamatergic interpeduncular nucleus neurons | | 纹身墨水会导致引流淋巴结发炎，并削弱对COVID-19疫苗的免疫反应。 | Capucetti, A. | PDF | N/A | Tattoo ink induces inflammation in the draining lymph node and impairs the immune response against a COVID-19 vaccine | | 由镶嵌RBD纳米颗粒诱导的交叉反应性沙贝科病毒抗体 | Fan, C. | PDF | N/A | Cross-reactive sarbecovirus antibodies induced by mosaic RBD-nanoparticles | | 小麦赤霉病菌（Zymoseptoria tritici）在田间多样性及效应子变异方面表现出局部差异。 | Tobian Herreno, A. | PDF | N/A | Zymoseptoria tritici show local differences in within-field diversity and effector variation | | 使用实验和模型评估浮游植物-细菌相互作用的四种潜在机制 | Weissberg, O. | PDF | N/A | Four Potential Mechanisms Underlying Phytoplankton-Bacteria Interactions Assessed Using Experiments and Models | | DNA超螺旋以依赖基因取向的方式调节真核生物的转录。 | Morao, A. K. | PDF | N/A | DNA supercoiling modulates eukaryotic transcription in a gene-orientation dependent manner | | DHX36/G4R1是一种G4解旋酶，其缺失会导致基因组不稳定，并在癌细胞中调节先天免疫基因的表达。 | Bartosik, A. R. | PDF | N/A | Loss of DHX36/G4R1, a G4 resolvase, drives genome instability and regulates innate immune gene expression in cancer cells | | 微管切割酶spastin调节纺锤体动态以促进布氏锥虫中的染色体分离 | Souza Onofre, T. | PDF | N/A | The microtubule-severing enzyme spastin regulates spindle dynamics to promote chromosome segregation in Trypanosoma brucei | | EPHA2依赖的Ephrin-B1信号通路支持口腔癌的自我更新能力和复发 | R, R. R. | PDF | N/A | EPHA2-dependent Ephrin-B1 signaling supports self-renewal ability and recurrence of oral cancer | | 小鼠背侧外侧膝状体核（dLGN）的视野特化 | Cha, K. | PDF | N/A | Visual field specializations in mouse dLGN | | spoVF操纵子亚基A和B在生物防治剂枯草芽孢杆菌中调控细胞形态和生物膜形成的作用 | Yang, Y. | PDF | N/A | Roles of spoVF operon subunits A and B in regulating cell morphology and biofilm formation in the biocontrol agent Bacillus subtilis | | 来自多种真菌病原体的细胞外囊泡能够诱导物种特异性和内吞作用依赖性的免疫调节。 | Kwaku, G. | PDF | N/A | Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation | | 通过靶向线粒体基因的实时PCR技术对Phytophthora pluvialis进行超灵敏检测 | O'Neill, R. A. | PDF | N/A | Ultra-sensitive detection of Phytophthora pluvialis by real-time PCR targeting a mitochondrial gene | | 皮肤老化领域的创新：仿生外泌体与天然外泌体的对比 | Salvaggio, A. | PDF | N/A | Innovations in skin aging: biomimetic exosomes versus natural exosomes | | 大型丝氨酸整合酶方向性控制的结构基础 | Shin, H. | PDF | N/A | Structural basis of directionality control in large serine integrases | | 使用机器人与功能性磁共振成像技术绘制手腕运动的神经控制力与阻抗图谱 | Schmidt, K. | PDF | N/A | Mapping the Neural Control of Force and Impedance of Wrist Movements Using Robotics and fMRI | | 突变体p53R175H相关的卵巢癌前体细胞对顺铂的保护作用需要SLC6A6牛磺酸转运蛋白的表达 | Polotaye, T. | PDF | N/A | Mutant p53R175H-Associated Protection of Ovarian Cancer Precursor Cells from Cisplatin Requires Expression of SLC6A6 Taurine Transporter | | 增加人类跑者的有效腿长是否对代谢有益？ | Bertschy, M. | PDF | N/A | Is increasing the effective leg length of a human runner metabolically beneficial? | | 多药耐药鲍曼不动杆菌中GyrA、MexB、FtsI、AtpD蛋白变异的建模 | Nik Mohd Nazri, N. Z. H. | PDF | N/A | Modeling of GyrA, MexB, FtsI, AtpD Protein Variants In Multidrug Resistant Acinetobacter baumannii | | 一种超长重链牛抗体能够中和SARS-CoV-2病毒，并能广泛地与沙贝科病毒（sarbecoviruses）发生反应。 | Tsoleridis, T. | PDF | N/A | An ultra-long heavy chain bovine antibody neutralizes SARS-CoV-2 and reacts broadly with sarbecoviruses. | | 基于人类诱导多能干细胞（iPSC）的共培养模型揭示了小胶质细胞与星形胶质细胞之间的神经炎症相互作用 | Tujula, I. | PDF | N/A | Human iPSC-based coculture model reveals neuroinflammatory crosstalk between microglia and astrocytes | | 这段英文翻译成中文是：

"基于情感效价的感觉-节律神经同步调节皮层-皮层下动态、注意力和记忆。"

解释： - "Valence-dependent" 指的是依赖于情感效价（即情感的正负性）。 - "sensory-rhythmic neural entrainment" 指的是感觉-节律神经同步，即大脑神经活动与外部节律的同步。 - "modulates" 意思是调节或调制。 - "cortico-subcortical dynamics" 指的是皮层-皮层下动态，即大脑皮层和皮层下结构之间的相互作用。 - "attention" 是注意力。 - "memory" 是记忆。

成年男性和女性人类钩虫（Ancylostoma ceylanicum）的单细胞转录组图谱

BioRxiv 2025-01-02 Papers

标题	作者	PDF链接	代码仓库	Title
纤毛方向性揭示了大脑皮层中主要神经元的缓慢反向运动，用于定位和层状结构的精细化	Yang, J.	PDF	N/A	Cilia Directionality Reveals a Slow Reverse Movement of Principal Neurons for Positioning and Lamina Refinement in the Cerebral Cortex
精神分裂症风险基因在人类神经元中的收敛性和非加性影响	Deans, P. M.	PDF	N/A	Convergent and non-additive impact of schizophrenia risk genes in human neurons
人类生长的因果模型及其使用时序稀疏数据的估计	Bunce, J. A.	PDF	N/A	A causal model of human growth and its estimation using temporally-sparse data
结合统计与机械建模，将离子通道基因与皮质神经元类型的生理特性联系起来	Bernaerts, Y.	PDF	N/A	Combined statistical-mechanistic modeling links ionchannel genes to physiology of cortical neuron types
CaBLAM！一种高对比度的生物发光Ca2+指示剂，源自工程化的细臂萤光素酶（Oplophorus gracilirostris luciferase）。	Lambert, G. G.	PDF	N/A	CaBLAM! A high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase
将人类tau病变患者样本在细胞中传代会产生异质性的纤维，其中一部分纤维会形成与疾病相关的折叠结构。	Zeng, Z.	PDF	N/A	Passaging Human Tauopathy Patient Samples in Cells Generates Heterogeneous Fibrils with a Subpopulation Adopting Disease Folds
使用AlphaFold、Rosetta和副本交换进行可靠的蛋白质-蛋白质对接	Harmalkar, A.	PDF	N/A	Reliable protein-protein docking with AlphaFold, Rosetta and replica-exchange
拟南芥中自噬的氧化还原调控：活性氧的不同影响	Robert, G.	PDF	N/A	Redox regulation of autophagy in Arabidopsis: differential effects of reactive oxygen species
温暖温度通过拦截N-羟基哌啶酸的生物合成来抑制植物的系统获得性抗性。	Shields, A.	PDF	N/A	Warm temperature suppresses plant systemic acquired resistance by intercepting N-hydroxypipecolic acid biosynthesis
大脑老化速度与亚洲儿童和老年人未来的执行功能相关	Cheng, S. F.	PDF	N/A	Rate of brain aging associates with future executive function in Asian children and older adults
高效且准确地以单细胞分辨率检测病毒序列，揭示了可能干扰宿主基因表达的新型病毒。	Luebbert, L.	PDF	N/A	Efficient and accurate detection of viral sequences at single-cell resolution reveals putative novel viruses perturbing host gene expression
组蛋白H2A.Z去乙酰化与去分化在梗死/ Tip60缺失的心肌细胞中的作用	Wang, X.	PDF	N/A	Histone H2A.Z Deacetylation and Dedifferentiationin Infarcted/Tip60-depleted Cardiomyocytes
一个突变的ASXL1-EHMT复合物在克隆性造血和慢性单核细胞白血病中导致异染色质功能障碍。	Dong, Z.	PDF	N/A	A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia
与新颖探索期间θ振荡而非涟漪振荡相关的海马CA1锥体神经元的同步集合。	Chen, E.-L.	PDF	N/A	Synchronous ensembles of hippocampal CA1 pyramidal neurons associated with theta but not ripple oscillations during novel exploration
脑信号复杂性和非周期性预测人类皮质脊髓兴奋性	Frohlich, J.	PDF	N/A	Brain signal complexity and aperiodicity predict human corticospinal excitability
真核生物转录因子的共转录因子依赖性差异涉及多个影响激活和自抑制的内在无序区域	Snyder, L. F.	PDF	N/A	Divergence in a Eukaryotic Transcription Factor's co-TF Dependence Involves Multiple Intrinsically Disordered Regions Affecting Activation and Autoinhibition
人类视觉皮层中可预测运动的多阶段渐进外推	Turner, W.	PDF	N/A	Progressive multi-stage extrapolation of predictable motion in human visual cortex
前额叶多巴胺活动对于快速威胁回避学习至关重要	Zeidler, Z. E.	PDF	N/A	Prefrontal dopamine activity is critical for rapid threat avoidance learning
双脑微状态：一种用于量化任务驱动的脑间不对称性的新型超扫描-脑电图方法	Li, Q.	PDF	N/A	Two-brain microstates: A novel hyperscanning-EEG method for quantifying task-driven inter-brain asymmetry
解码可卡因自我给药过程中次级运动皮层神经元活动：来自纵向体内钙成像的见解	Chen, Y.	PDF	N/A	Decoding Secondary Motor Cortex Neuronal Activity during Cocaine Self-Administration: Insights from Longitudinal in vivo Calcium Imaging
以下是这段文字的中文翻译：

可扩展、高质量工程化干细胞来源的SIRPα-细胞外囊泡的双模式作用用于治疗急性肝衰竭

翻译说明： - Dual-mode action：双模式作用，指该治疗方法具有两种不同的作用机制。 - scalable：可扩展的，表示该技术可以大规模生产或应用。 - high-quality engineered：高质量工程化的，指通过工程技术手段改造的高质量产品。 - stem cell-derived：干细胞来源的，表示这些细胞外囊泡是从干细胞中提取或衍生的。 - SIRPα-extracellular vesicles：SIRPα-细胞外囊泡，SIRPα是一种蛋白质，这里指含有SIRPα的细胞外囊泡。 - treating acute liver failure：治疗急性肝衰竭，指该技术用于急性肝衰竭的治疗。

希望这个翻译对你有帮助！ | Kim, S. | PDF | N/A | Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure | | 增强系统发育独立对比：通过离群值和分布引导的相关性应对突发的进化转变 | Chen, Z.-L. | PDF | N/A | Enhancing Phylogenetic Independent Contrasts: Addressing Abrupt Evolutionary Shifts with Outlier- and Distribution-Guided Correlation | | 一种细胞可渗透的荧光探针揭示了由不同GPCR激动剂在神经元中引发的PI(4,5)P2动态的时间多样性 | Kundu, R. | PDF | N/A | A Cell-Permeable Fluorescent Probe Reveals Temporally Diverse PI(4,5)P2 Dynamics Evoked by Distinct GPCR Agonists in Neurons | | 胰腺β细胞中GLP-1R胆固醇结合位点的分子定位与功能验证 | Oqua, A. I. | PDF | N/A | Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells | | 胰腺β细胞中GLP-1R胆固醇结合位点的分子定位与功能验证 | Oqua, A. I. | PDF | N/A | Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells | | miR-184通过调控dilp8来控制正常生长条件下的发育时间，并在应对发育扰动时发挥作用。 | Fernandes, J. | PDF | N/A | miR-184 modulates dilp8 to control developmental timing during normal growth conditions and in response to developmental perturbations | | 一个动力简单步行模型修改了恢复率的定义：人类在双支撑阶段的步行与钟摆运动有显著差异 | Hosseini-Yazdi, S.-S. | PDF | N/A | A Powered Simple Walking Model Modifies the Rate of Recovery Definition: Human Walking Deviates Drastically from Pendular Motion During the Double Support Phase | | 直接RNA测序（RNA004）技术能够提升转录组分析的准确性，并实现近乎实时的甲基化追踪，这对于医学应用具有重要意义。 | Hewel, C. | PDF | N/A | Direct RNA sequencing (RNA004) allows for improved transcriptome assessment and near real-time tracking of methylation for medical applications | | 姜黄素和5-溴吲哚-3-甲醛对铜绿假单胞菌群体感应依赖性毒力因子抑制的影响 | Gonzalez, G. M. | PDF | N/A | Effect of curcumin and 5-bromoindole-3-carboxyaldehyde on the inhibition of Quorum sensig-dependent virulence factors in Pseudomonas aeruginosa | | 为了解决皮层数据集中的过度分割和快速状态转换问题，我们提出了一种粘性泊松隐马尔可夫模型。 | Li, T. | PDF | N/A | A sticky Poisson Hidden Markov Model for solving the problem of over-segmentation and rapid state switching in cortical datasets | | 《涡虫干细胞分化的调控逻辑》 | Perez-Posada, A. | PDF | N/A | The Regulatory Logic of Planarian Stem Cell Differentiation | | PAM识别的灵活性扩展了xCas9的DNA靶向能力 | Hossain, K. A. | PDF | N/A | Flexibility in PAM Recognition Expands DNA Targeting in xCas9 | | 基于人工智能的KATP通道药物伴侣的发现及冷冻电镜结构解析 | Elsheikh, A. | PDF | N/A | AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone | | 三碘甲状腺原氨酸和黄芩素的双重干预双向上调Klotho，减轻老年BALB/c小鼠的慢性肾病及其并发症。 | Mohanty, S. K. | PDF | N/A | A Dual intervention of Triiodothyronine and Baicalein bi-directionally upregulates Klotho with attenuation of chronic kidney disease and its complications in aged BALB/c mice | | 在氧化还原梯度环境中，革兰氏阳性菌Microbacterium deferre sp. nov. A1-JK通过基于黄素的细胞外电子传递在含氧条件下进行电子转移。 | Lustermans, J. J. M. | PDF | N/A | Flavin-based extracellular electron transfer under oxic conditions by Gram-positive Microbacterium deferre sp. nov. A1-JK in redox-graded environments | | 听觉皮层通过选择性多感官增强学习区分视听线索 | Chang, S. | PDF | N/A | Auditory Cortex Learns to Discriminate Audiovisual Cues through Selective Multisensory Enhancement | | 作为宏蛋白质组学工具的数据非依赖性采集质谱：使用模型微生物组的实验室间比较 | Rajczewski, A. T. | PDF | N/A | Data-Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome | | RanBALL：一种用于识别B细胞急性淋巴细胞白血病亚型的集成随机投影模型 | Li, L. | PDF | N/A | RanBALL: An Ensemble Random Projection Model for Identifying Subtypes of B-cell Acute Lymphoblastic Leukemia | | 成纤维细胞生长因子诱导的14在骨骼肌修复过程中调控卫星细胞的自我更新和扩增 | Tomaz Da Silva, M. | PDF | N/A | Fibroblast growth factor-inducible 14 regulates satellite cell self-renewal and expansion during skeletal muscle repair | | 皮肤通过天然保湿因子实现水合作用，这是一个关于氢键网络的故事 | MARTIN, M. | PDF | N/A | Skin hydration by natural moisturizing factors, a story of H-bond networking | | 由机械压缩引发的古菌中类似组织的多细胞发育 | Rados, T. | PDF | N/A | Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea | | 突触小泡内吞作用缺陷是导致GBA相关帕金森病和路易体痴呆认知功能障碍的基础。 | Vidyadhara, D. J. | PDF | N/A | Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson's disease and Dementia with Lewy bodies | | WRAD核心扰动损害DNA复制保真度，促进胰腺癌中的免疫编辑 | Citron, F. | PDF | N/A | WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer | | 记忆系统适应不良损害了自闭症Cntnap2基因敲除小鼠模型中CA1依赖性时间绑定和陈述性记忆

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一个关于西北欧节肢动物生活史和生态特征的深入数据集

翻译说明： - "in-depth" 翻译为 "深入的" - "dataset" 翻译为 "数据集" - "northwestern European" 翻译为 "西北欧的" - "arthropod" 翻译为 "节肢动物" - "life histories" 翻译为 "生活史" - "ecological traits" 翻译为 "生态特征"

这段内容描述了一个专门为自由活动的大鼠设计的电子尼古丁输送系统，该系统能够实现鼻吸式电子烟气溶胶的吸入，并对其进行了描述和验证。 | Odum, A. L. | PDF | N/A | The Rodent Electronic Nicotine Delivery System: Description and Validationof an Apparatus for Nose-Only E-Cigarette Aerosol Inhalation in Freely Moving Rats | | 来自智利巴塔哥尼亚北部的Eleginops maclovinus的局部适应性基因组信号 | Claure, C. E. | PDF | N/A | Genomic signals of local adaptation in Eleginops maclovinus from Northern Chilean Patagonia | | 智利巴塔哥尼亚北部Eleginops maclovinus的局部适应性基因组信号 | Claure, C. E. | PDF | N/A | Genomic signals of local adaptation in Eleginops maclovinus from Northern Chilean Patagonia | | 蛋白质CREATE技术实现了从头合成蛋白质结合剂的闭环设计。 | Lourenco, A. L. | PDF | N/A | Protein CREATE enables closed-loop design of de novo synthetic protein binders | | 空间有序的合子基因组激活实现胚胎质量控制 | Qian, W. | PDF | N/A | Spatially ordered zygotic genome activation fulfills embryo quality control | | 新分离的基因组和全球海洋宏基因组解析了SAR11的生态相关单元 | Freel, K. C. | PDF | N/A | New isolate genomes and global marine metagenomes resolve ecologically relevant units of SAR11 | | 对单个线粒体成分的定量分析揭示了小线粒体网络在启动肿瘤形成中的早期作用。 | Saini, M. | PDF | N/A | Quantitative analyses of individual mitochondrial components reveal an early role of small-mitochondrial-networks in priming neoplasticity | | 通过海洋传播实现陆地植物的全球分布 | Vatanparast, M. | PDF | N/A | Global distribution of a land plant by means of oceanic dispersal | | 两种新型绿僵菌制剂在防治马铃薯种植中金针虫的效果 | Paluch, M. | PDF | N/A | The effectiveness of two new Metarhizium brunneum formulations against wireworms in potato cultivation | | 镉的摄入不会破坏亚社会性昆虫幼体间微生物群落的社会传播。 | Cheutin, M.-C. | PDF | N/A | Cadmium ingestion does not disrupt the social transmission of the microbiome in juveniles of a subsocial insect | | 核苷酸编码控制着Lis1解除动力蛋白自抑制的能力。 | Geohring, I. C. | PDF | N/A | A nucleotide code governs Lis1's ability to relieve dynein autoinhibition | | 将这段翻译成中文为：工程化多重合成呼吸生物标志物作为诊断探针。 | Wang, S.-T. | PDF | N/A | Engineering Multiplexed Synthetic Breath Biomarkers as Diagnostic Probes | | 预测压力恢复力的睡眠模式因性别而异。 | Bush, B. J. | PDF | N/A | Sleep patterns predicting stress resilience are dependent on sex | | 非核小体（CENP-A/H4）2 - DNA复合物作为着丝粒组织的可能平台 | Ali-Ahmad, A. | PDF | N/A | Non-nucleosomal (CENP-A/H4)2 - DNA complexes as a possible platform for centromere organization | | 核篮蛋白Mlp1和Nup2驱动热休克诱导的三维基因组重构 | Mohajan, S. | PDF | N/A | Nuclear basket proteins Mlp1 and Nup2 drive heat shock-induced 3D genome restructuring | | 胎儿癌基因NUAK2是胶质母细胞瘤中的一个新兴治疗靶点。 | Jo, H. | PDF | N/A | A fetal oncogene NUAK2 is an emerging therapeutic target in glioblastoma. | | 慢性退行性唾液腺功能衰竭可以通过恢复线粒体功能来逆转。 | Li, J. | PDF | N/A | Chronic degenerative failure of salivary glands can be reversed through restoring mitochondrial function | | TOR和热休克反应通路在蛋白质毒性应激期间调节过氧化物酶体的生物发生。 | Shukla, N. | PDF | N/A | TOR and heat shock response pathways regulate peroxisome biogenesis during proteotoxic stress | | STN β 振荡对帕金森病步态中下肢肌肉活动的作用 | Simpson, T. G. | PDF | N/A | The role of STN beta oscillations on lower extremity muscle activity in Parkinsonian stepping | | 评估BNST GABA神经元在后退条件抑制中的作用 | Ly, A. | PDF | N/A | Assessing the role of BNST GABA neurons in backward conditioned suppression | | 扰动全脑模型中的大脑层级结构：药物治疗后抑郁症的应用研究 | Socoro Garrigosa, M. | PDF | N/A | Perturbing whole-brain models of brain hierarchy: an application for depression following pharmacological treatment | | 机械敏感的DEG/ENaC通道DEGT-1是线虫前肠运动的本体感受器。 | Bayer, E. A. | PDF | N/A | The mechanosensory DEG/ENaC channel DEGT-1 is a proprioceptor of C. elegans foregut movement | | 机械敏感的DEG/ENaC通道DEGT-1是线虫前肠运动的感受器。 | Bayer, E. A. | PDF | N/A | The mechanosensory DEG/ENaC channel DEGT-1 is a proprioceptor of C. elegans foregut movement | | 《艺术家的头脑：一种数据融合方法以刻画专业视觉艺术家的神经基础》

这篇论文探讨了专业视觉艺术家的大脑活动特征，采用了一种数据融合的方法来研究艺术家在创作过程中的神经机制。通过整合多种神经影像数据，研究旨在揭示艺术家在视觉创作中独特的大脑活动模式，从而更好地理解艺术创作背后的神经科学基础。 | Taskiran, E. | PDF | N/A | The Artists' Brain: A Data Fusion Approach to Characterize the Neural Bases of Professional Visual Artists | | VGluT3 BNST神经元传递GABA并限制摄食，而不影响奖赏或厌恶处理 | Ly, A. | PDF | N/A | VGluT3 BNST neurons transmit GABA and restrict feeding without affecting rewarding or aversive processing | | 催眠-个人电脑：通过主成分分析和电生理信号的隐马尔可夫模型揭示睡眠动态 | Guendelman, M. | PDF | N/A | The Hypno-PC: Uncovering Sleep Dynamics through Principal Component Analysis and Hidden Markov Modeling of Electrophysiological Signals | | 额叶眼区神经元预测跨眼跳视觉稳定性的“反贝叶斯”判断，而非贝叶斯判断 | Subramanian, D. | PDF | N/A | Frontal eye field neurons predict "anti-Bayesian" but not Bayesian judgments of visual stability across saccades | | CLN5缺乏症会损害巴顿病中的葡萄糖摄取。 | MARCHESE, M. | PDF | N/A | CLN5 deficiency impairs glucose uptake in Batten disease | | CLN5缺乏症会影响巴顿病中的葡萄糖摄取。 | Marchese, M. | PDF | N/A | CLN5 deficiency impairs glucose uptake in Batten disease | | 这段文字的中文翻译是：

迷走神经节与肺神经内分泌细胞之间的神经回路调节肺部炎症反应

解释： - Neural circuits 翻译为 神经回路 - nodose ganglion 翻译为 迷走神经节（迷走神经的下神经节） - pulmonary neuroendocrine cells 翻译为 肺神经内分泌细胞 - regulate 翻译为调节 - lung inflammatory responses 翻译为 肺部炎症反应

在这项研究中，我们探讨了通过DCAF16招募的靶向胶选择性降解BRD9的机制，并在体内验证了这一概念。BRD9是一种与染色质重塑和基因表达调控相关的蛋白质，其异常表达与多种疾病有关。通过设计一种能够特异性结合BRD9并招募DCAF16的靶向胶，我们实现了对BRD9的选择性降解。研究详细阐明了这一过程的作用模式，并通过体内实验验证了其可行性和效果。这一发现为开发新型靶向治疗策略提供了重要的理论依据和实验支持。 | Hughes, S. J. | PDF | N/A | Selective degradation of BRD9 by a DCAF16-recruiting targeted glue: mode of action elucidation and in vivo proof of concept | | PRC1通过两种不同的阻力模式抵抗微管的滑动，这是由于重叠微管之间间距的变化所导致的。 | Steckhahn, D. | PDF | N/A | PRC1 resists microtubule sliding in two distinct resistive modes due to variations in the separation between overlapping microtubules | | Trogocytosis介导的FOLR2从护士样细胞向慢性淋巴细胞白血病（CLL）细胞的转移与其激活和增殖相关。 | Domagala, M. | PDF | N/A | Trogocytosis-mediated transfer of FOLR2 from Nurse-like cells to CLL cells is linked to their activation and proliferation | | 在蓝光和紫外线辐射下，拟南芥中UVR8和隐花色素对光合作用的保护 | Morales, L. O. | PDF | N/A | Protection of photosynthesis by UVR8 and cryptochromes in Arabidopsis under blue and UV radiation | | 异步布尔网络模型的最优推断 | Karlebach, G. | PDF | N/A | Optimal Inference of Asynchronous Boolean Network Models | | 使用绿色空间虚拟现实技术预防压力引起的工作记忆损伤 | Xu, Y. | PDF | N/A | Using green space virtual reality to prevent stress-induced working memory impairment | | 慢性金黄色葡萄球菌感染骨细胞会促进细胞内形成一种“存活但不可培养”的表型。 | Gunn, N. J. | PDF | N/A | Chronic Staphylococcus aureus infection of osteocytes promotes an intracellular viable-but-non-culturable phenotype | | 一个简单的硅胶弹性体定植模型揭示了白色念珠菌和金黄色葡萄球菌在生物膜形成过程中相互作用的复杂性。 | McConnell, G. | PDF | N/A | A simple silicone elastomer colonisation model highlights complexities of Candida albicans and Staphylococcus aureus interactions in biofilm formation. | | 碳源、细胞密度和微生物群落通过环境硝酸盐控制霍乱弧菌表面定植的抑制作用。 | James, J. | PDF | N/A | Carbon source, cell density, and the microbial community control inhibition of V. cholerae surface colonization by environmental nitrate | | 小基因组大小确保了高山姜的适应性灵活性。 | Xiao, Q.-S. | PDF | N/A | The small genome size ensures adaptive flexibility for an alpine ginger | | 以下是这段英文的中文翻译：

铜绿假单胞菌MsbA被Zn2+激活的分子基础

翻译说明： - "Molecular basis" 翻译为 "分子基础" - "activation" 翻译为 "激活" - "Pseudomonas aeruginosa" 是细菌名称，翻译为 "铜绿假单胞菌" - "MsbA" 是一种蛋白质，通常保留英文名称 - "Zn2+" 是锌离子，保留化学符号

希望这对你有帮助！ | Lyu, J. | PDF | N/A | Molecular basis for the activation of Pseudomonas aeruginosa MsbA by Zn2+ | | 具有增强亲水性、荧光性和亮度的醚基罗丹明用于超分辨率成像 | Fang, X. | PDF | N/A | Ether Rhodamines with Enhanced Hydrophilicity, Fluorogenicity, and Brightness for Super-Resolution Imaging | | 蛋白质条形码与下一代蛋白质测序技术在多路复用蛋白质选择、分析与追踪中的应用 | Chinnaraj, M. | PDF | N/A | Protein Barcoding and Next-Generation Protein Sequencing for Multiplexed Protein Selection, Analysis, and Tracking | | 肺炎克雷伯菌细菌微区室主要壳组件之间的混杂结构交叉兼容性 | Barthe, L. | PDF | N/A | Promiscuous structural cross-compatibilities between major shell components of Klebsiella pneumoniae bacterial microcompartments | | 前列腺素转运蛋白的结构与翻译后修饰 | Yu, P. | PDF | N/A | Structure and Post-Translational Modification of the Prostaglandin Transporter | | 埃及伊蚊中肠胰凝乳蛋白酶在血液餐蛋白质消化或繁殖力中没有显著作用。 | Rascon, A. A. | PDF | N/A | Aedes aegypti midgut chymotrypsin has no significant role in blood meal protein digestion or fecundity | | 冠状病毒主要蛋白酶的酶动力学模型，包括二聚化和配体结合 | La, V. N. T. | PDF | N/A | Enzyme kinetics model for the coronavirus main protease including dimerization and ligand binding | | A20的线性泛素结合基序抑制TH17/22细胞的致病性激活及IL-22驱动的肠炎 | Bowman, C. J. | PDF | N/A | A20's Linear Ubiquitin Binding Motif Restrains Pathogenic Activation of TH17/22 cells and IL-22 Driven Enteritis | | 使用傅里叶变换红外光谱法区分结核分枝杆菌和牛分枝杆菌 | Guterres, K. B. | PDF | N/A | Discrimination between Mycobacterium tuberculosis and Mycobacterium bovis using Fourier Transform Infrared Spectroscopy | | 产甲烷菌与短链脂肪酸的微生物产量变化及人体可代谢能量的变化有关。 | Dirks, B. | PDF | N/A | Methanogens are associated with altered microbial production of short-chain fatty acids and human-host metabolizable energy | | 脓肿分枝杆菌促进铜绿假单胞菌生物膜形成和抗生素耐受性 | McDaniel, M. S. | PDF | N/A | Mycobacterium abscessus promotes Pseudomonas aeruginosa biofilm formation and antibiotic tolerance | | 解析急性蛙病毒（MRV）感染对鳜鱼幽门盲囊的全球响应揭示浆膜炎及随后腹水的形成过程 | Zhang, W. | PDF | N/A | Dissection of the Global Responses of Mandarin Fish Pyloric Caecum to An Acute Ranavirus (MRV) Infection Reveals the Formation of Serositis and Then Ascites | | 脑炎性虫媒病毒受体识别转变的分子基础 | Fan, X. | PDF | N/A | Molecular basis for shifted receptor recognition by an encephalitic arbovirus | | 霉菌膜以差异化和异质性的方式限制抗生素的渗透。 | Lepori, I. | PDF | N/A | The mycomembrane differentially and heterogeneously restricts antibiotic permeation | | 霸凌噬菌体：一种编码志贺毒素的原噬菌体干扰共宿主原噬菌体的诱导 | Litvak, Y. | PDF | N/A | The bully phage: A Shiga toxin-encoding prophage interferes with the induction of co-hosted prophages | | 副转基因技术：工程化肠杆菌共生体及产Cry1Ac蛋白肠杆菌在农作物生产中用于生物防治棉铃虫害虫的动态研究 | Ojha, A. | PDF | N/A | Paratransgenesis: The dynamics of engineered Enterobacter symbionts and Cry1Ac-producing Enterobacter for biocontrol of Helicoverpa insect pests in crop production | | 聚合酶14缺乏小鼠中沙门氏菌病的恶化 | Vedantham, M. | PDF | N/A | Exacerbated salmonellosis in poly(ADP-ribose) polymerase 14 deficient mice | | 自噬介导的AXL和TIM-1下调促进持续寨卡病毒感染 | Liu, S.-L. | PDF | N/A | Autophagy-Mediated Downregulation of AXL and TIM-1 Promotes Sustained Zika Virus Infection | | 单碱基m6A表观转录组学揭示了原代CD4+ T细胞中HIV-1与宿主相互作用的新靶点 | Huang, S. | PDF | N/A | Single-base m6A epitranscriptomics reveals novel HIV-1 host interaction targets in primary CD4+ T cells | | 长读长全基因组测序为研究与原发性脑型暗色丝孢霉病相关的嗜神经性暗色真菌的生物学特性、应激适应及毒力提供了新的见解。 | Samaddar, A. | PDF | N/A | Long-read whole-genome sequencing offers novel insights into the biology, stress adaptation, and virulence of neurotropic dematiaceous fungi associated with primary cerebral phaeohyphomycosis | | LGR二聚体的结构——糖蛋白激素受体的进化前体 | Gong, Z. | PDF | N/A | Structure of an LGR dimer - an evolutionary predecessor of glycoprotein hormone receptors | | 生长激素/胰岛素样生长因子信号通过调节酮己糖激酶的表达来拮抗肝脏果糖代谢。 | Elsaid, S. A. | PDF | N/A | Hepatic fructose metabolism is antagonized by growth hormone/insulin-like growth factor signaling via regulation of ketohexokinase expression | | 陆源有机物加剧密西西比河源头沉积物中的甲烷排放 | Sauer, H. M. | PDF | N/A | Terrestrial Organic Matter Amplifies Methane Emissions Across Sediments of the Mississippi River Headwaters | | 对空中热成像视频技术估算大型哺乳动物种群数量的实验评估 | McElhinny, J. S. | PDF | N/A | Experimental assessment of large mammal population estimates from airborne thermal videography | | SSARP：一个R语言包，用于利用网络数据库轻松创建物种-面积关系和物种形成-面积关系 | Martinet, K. M. | PDF | N/A | SSARP: An R Package for Easily Creating Species- and Speciation- Area Relationships Using Web Databases | | 《水韭属（水韭目）的孢子形态与进化》 | Larsen, E. | PDF | N/A | Spore morphology and evolution in Isoetes (Isoetales) | | 社会寄生蚂蚁基因组创新与缺失的趋同进化痕迹 | Harrison, M. C. | PDF | N/A | Convergent Evolutionary Traces of Genomic Innovations and Depletions in Socially Parasitic Ants | | 在早期卵泡发生过程中，卵母细胞中线粒体DNA完整性的跨代维持 | Xie, Q. | PDF | N/A | Trans-generational maintenance of mitochondrial DNA integrity in oocytes during early folliculogenesis | | 在脑血管疾病的Mthfr677C>T小鼠模型中视网膜血管功能障碍 | Reagan, A. M. | PDF | N/A | Retinal vascular dysfunction in the Mthfr677C>T mouse model of cerebrovascular disease | | 单细胞调控DNA-蛋白质相互作用图谱 | Chi, W. Y. | PDF | N/A | Single-cell mapping of regulatory DNA:Protein interactions | | 实验室规模麦芽质量评估的低成本台式麦芽制备方案的开发与质量评价 | Rani, H. | PDF | N/A | Development and quality assessment of low-cost benchtop malting protocol for laboratory-scale malt quality evaluation | | 识别和表征由RNA替代质子化引起的移位GU摆动对 | Saon, M. S. | PDF | N/A | Identification and characterization of shifted GU wobble pairs resulting from alternative protonation of RNA | | 托马斯克拉维利亚分支菌（Thomasclavelia ramosa）免疫球蛋白A蛋白酶的结构揭示了其模块化和可最小化的架构，与其他免疫球蛋白A蛋白酶明显不同。 | Tran, N. | PDF | N/A | Structure of the Thomasclavelia ramosa immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases | | 平衡EL222的剂量和光照可以改善在Komagataella phaffii中光遗传学诱导蛋白质生产的效果。 | Hoffman, S. M. | PDF | N/A | Balancing doses of EL222 and light improves optogenetic induction of protein production in Komagataella phaffii | | 鳞尾器官在Pel's鳞尾飞鼠的树栖运动中增强了静态稳定性 | Schulz, A. K. | PDF | N/A | Scaly-Tail Organ Enhances Static Stability during Pel's Scaly-tailed Flying Squirrels' Arboreal Locomotion | | 微环境在PDAC肿瘤类器官表型、代谢和耐药性中作用的定量评估 | Sorzabal, I. | PDF | N/A | Quantitative evaluation of the role of the microenvironment in the phenotype, metabolism, and drug resistance of PDAC tumor organoids | | 对斑马鱼遗传的lncRNA和circRNA库进行全面分析 | Joshi, D. C. | PDF | N/A | A comprehensive analysis of the inherited lncRNA and circRNA repertoire of zebrafish | | 使用ColabFold推动无序区域结构预测的极限：进展与见解 | Rieth, M. | PDF | N/A | Pushing the limits of structure prediction in regions of disorder using ColabFold: Progress and insights | | 这段文字可以翻译为：

“受体酪氨酸激酶超家族中的结构保守性与差异性”

解释： - Structural conservation 指的是在不同蛋白质或分子中，某些结构特征在进化过程中保持相对不变。 - Divergence 指的是在进化过程中出现的差异或变化。 - Receptor Tyrosine Kinase (RTK) 是一类重要的细胞表面受体，参与细胞信号传导。 - Superfamily 指的是具有相似结构和功能的一类蛋白质家族。

整体意思是研究受体酪氨酸激酶超家族中，不同成员之间在结构上的保守性（相似性）和差异性（变化）。 | Fassler Bakhman, A. | PDF | N/A | Structural conservation and divergence across the Receptor Tyrosine Kinase superfamily | | 酶负载囊泡中通过增强扩散产生力的机制 | Eberhard, E. | PDF | N/A | Force Generation by Enhanced Diffusion in Enzyme-Loaded Vesicles | | 探索包含APP C99的三元脂质混合物中相分离的动力学和机制：原子级与粗粒度分子动力学模拟的对比 | Pantelopulos, G. A. | PDF | N/A | Exploring the kinetics and mechanism of phase separation in ternary lipid mixtures containing APP C99 using atomistic vs coarse-grained MD simulations | | 超螺旋对拓扑域中细菌转录的差异效应 | Goldberg, B. I. | PDF | N/A | Differential effect of supercoiling on bacterial transcription in topological domains | | Snf2型ATP酶介导染色质重塑的机制 | Malik, D. | PDF | N/A | Mechanisms of chromatin remodeling by a Snf2-type ATPase | | 一款开源的3D打印显微镜，配备大型CNC载物台 | Degut, C. | PDF | N/A | An open-sourced 3D printable microscope with a large CNC stage | | 缺氧诱导的活跃动力学促进早期肿瘤发生 | Wang, Z. | PDF | N/A | Hypoxia-Induced Active Dynamics Promotes Early Tumorigenesis | | 一个整合了多尺度计算机模拟建模和实验数据的框架，能够预测CD33 CAR-NK细胞在不同靶细胞类型中的细胞毒性。 | Ahmad, S. | PDF | N/A | A framework integrating multiscale in-silico modeling and experimental data predicts CD33 CAR-NK cytotoxicity across target cell types | | 转录机制将ecDNAs锚定在有丝分裂染色体上进行分离 | Xie, Y. | PDF | N/A | Transcription Machinery Anchors ecDNAs to Mitotic Chromosomes for Segregation | | RAGE信号和2型糖尿病对小鼠皮质骨力学、结构和材料特性的性别特异性影响 | Hung, T. | PDF | N/A | The sex-specific effects of RAGE signaling and Type 2 Diabetes on mouse cortical bone mechanics, structure, and material properties | | 评估治疗MFN2相关脂肪营养不良的候选“生死抉择”策略 | Luijten, I. | PDF | N/A | Evaluation of Candidate ''Kill or Cure'' Strategies to Treat MFN2-related Lipodystrophy | | 苹果果实形状的差异与果实大小无关。 | DeViller, K. | PDF | N/A | Differences in apple fruit shape are independent of fruit size | | 通过机器学习支持的非靶向代谢组学揭示植物对干旱和二氧化碳升高的营养和代谢反应 | Chang, H.-F. | PDF | N/A | Plant nutritional and metabolic responses to drought and elevated CO2 revealed by machine learning-enabled non-targeted metabolomics | | 稳定表达膜锚定流感神经氨酸酶的荧光条形码细胞系 | Finney, J. | PDF | N/A | Fluorescence-barcoded cell lines stably expressing membrane-anchored influenza neuraminidases | | 巨噬细胞活化过程中鞘脂代谢的解决与非解决动态：时间分辨代谢分析 | Chiappa, N. | PDF | N/A | Resolving vs. Non-resolving Sphingolipid Dynamics During Macrophage Activation: A Time-resolved Metabolic Analysis | | 体内衣康酸追踪揭示了其降解途径和周转动力学 | Cordes, T. F. | PDF | N/A | In vivo itaconate tracing reveals degradation pathway and turnover kinetics | | 从实验线索到理论建模：生命早期阶段与膜接管相关的进化 | Ma, W. | PDF | N/A | From experimental clues to theoretical modeling: Evolution associated with the membrane-takeover at an early stage of life | | 这段文字可以翻译为：

“具有表型多样性和环境波动的种群模型展示了适应与灭绝的参数机制”

其中： - Population Models 指的是“种群模型” - Phenotypic Diversity 指的是“表型多样性” - Fluctuating Environment 指的是“环境波动” - Parameter Regimes 指的是“参数机制”或“参数范围” - Adaptation vs. Extinction 指的是“适应与灭绝”

通过聚乙烯醇水凝胶珠固定蓝藻（Synechocystis）实现持续异丁烯生产

翻译说明： - Sustained：持续的 - Isobutene Production：异丁烯生产 - Synechocystis：蓝藻（一种光合微生物） - Entrapped：固定、包埋 - Polyvinyl Alcohol Hydrogel Beads：聚乙烯醇水凝胶珠

BioRxiv 2025-01-01 Papers

标题	作者	PDF链接	代码仓库	Title
匹罗卡品诱导的癫痫持续状态后，星形胶质细胞中持续的DNA甲基化和稳态基因的下调：对癫痫发生的影响	Gomez Cuautle, D. D.	PDF	N/A	Persistent DNA methylation and downregulation of homeostatic genes in astrocytes after pilocarpine-induced status epilepticus: Implications for epileptogenesis
CD44和Ezrin通过限制表皮生长因子受体（EGF受体）的流动性，生成了一种新的细胞骨架信号模块的空间排列，从而驱动基于膜泡（bleb）的细胞迁移。	Jha, A.	PDF	N/A	CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration
Empathi：基于嵌入的噬菌体蛋白质注释工具，通过分层分配实现	Boulay, A.	PDF	N/A	Empathi: Embedding-based Phage Protein Annotation Tool by Hierarchical Assignment
YX0798 是一种高效、选择性且口服有效的 CDK9 抑制剂，用于治疗侵袭性淋巴瘤。	Jiang, V.	PDF	N/A	YX0798 Is a Highly Potent, Selective, and Orally Effective CDK9 Inhibitor for Treating Aggressive Lymphoma
Tetralone-ABA 能够增强葡萄藤（包括欧洲葡萄 V. vinifera 和杂交葡萄 V. hybrid）的冬季抗寒能力，减少其脱锻炼过程，并延迟芽的萌发。	Wang, H.	PDF	N/A	Tetralone-ABA enhances winter cold acclimation, reduces deacclimation, and delays budbreak in V. vinifera and V. hybrid grapevines
人类趋避冲突的电路动力学	Staveland, B. R.	PDF	N/A	Circuit dynamics of approach-avoidance conflict in humans
通过使用新表位抗体P90对HD（亨廷顿病）人类和小鼠脑组织进行Western blot和免疫染色检测HTTex1p，揭示了CAG重复扩增对其大小、溶解性以及对MSH3沉默反应的影响。	Sapp, E.	PDF	N/A	Detection of HTTex1p by western blot and immunostaining of HD human and mouse brain using neo-epitope antibody P90 highlights impact of CAG repeat expansion on its size, solubility, and response to MSH3 silencing
大脑语言激活及其与认知和语言测量指标的关系	Balboni, I.	PDF	N/A	Brain activation for language and its relationship to cognitive and linguistic measures
不同的机制将驱动蛋白功能的获得与丧失与轴突变性联系起来。	Liew, Y.-T.	PDF	N/A	Different mechanisms link gain and loss of kinesin functions to axonal degeneration
在阿尔茨海默病神经病理学发病时，对人类内嗅皮层进行细胞类型特异性分析	Rodriguez-Rodriguez, P.	PDF	N/A	Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer's disease neuropathology
小鼠初级视觉皮层对冲突性双眼刺激的皮质反应	Montgomery, D. P.	PDF	N/A	Cortical responses to conflicting binocular stimuli in mouse primary visual cortex
神经生长因子信号调节轴突维持蛋白的丰度及沃勒变性的动力学	Danos, J. A.	PDF	N/A	Nerve Growth Factor Signaling Tunes Axon Maintenance Protein Abundance and Kinetics of Wallerian Degeneration
Nurr1调控屏状核的发育与功能	Yan, K.	PDF	N/A	Nurr1 orchestrates claustrum development and functionality
极低水活性条件下的生命极限：太阳能盐场（智利阿塔卡马盐沼）中的锂浓度池	Demergasso, C.	PDF	N/A	The limit of life at extremely low water activity:Lithium-concentration ponds in a solar saltern(Salar de Atacama, Chile)
ZapA采用双重机制来促进大肠杆菌中Z环的形成。	Cui, Y.	PDF	N/A	ZapA employs a two-pronged mechanism to facilitate Z ring formation in Escherichia coli
在生长中的神经元中，CoREST-2和RE-1对H3K9me2异染色质的动态平衡调控	Drube, J. F.	PDF	N/A	Dynamic balance of H3K9me2 heterochromatin by CoREST-2 and RE-1 in growing neurons
Argonaute蛋白调控精子生成转录程序的时间进程。	Carro, M. d. l. M.	PDF	N/A	Argonaute proteins regulate the timing of the spermatogenic transcriptional program
单细胞和空间转录组学揭示了B染色体在驱动植物入侵性中的作用	Wang, C.	PDF	N/A	Single-cell and spatial transcriptomics uncover the role of B chromosomes in driving plant invasiveness
40S核糖体亚基通过一维扩散在mRNA上扫描寻找起始密码子。	Wakabayashi, H.	PDF	N/A	40S ribosomal subunits scan mRNA for the start codon by one-dimensional diffusion
虹膜隐窝可能降低闭角型青光眼的发生风险：一项基于临床和人类虹膜数据的计算生物力学研究	Tan, R. K. Y.	PDF	N/A	Iris Crypts Could Reduce the Chance of Angle Closure: A Computational Biomechanics Study Derived from Clinical and Human Iris Data
在激光扫描显微镜中通过结构化检测进行波前估计	Fersini, F.	PDF	N/A	Wavefront estimation through structured detection in laser scanning microscopy
利用Bambu-Clump从单细胞和空间长读长RNA测序数据中进行异构体水平的发现、定量及融合分析。	Sim, A. D.	PDF	N/A	Isoform-level discovery, quantification and fusion analysis from single-cell and spatial long-read RNA-seq data with Bambu-Clump
通过新型染色质相互作用数据标准化方法提升增强子-启动子环的检测	Wang, X.	PDF	N/A	Boosting the detection of enhancer-promoter loops via novel normalization methods for chromatin interaction data
微生物通用模型：利用大型语言模型进行情境化微生物组分析	Zhang, H.	PDF	N/A	Microbial general model: Leveraging large language model for contextualized microbiome analysis
代表性荧光蛋白中双光子吸收的方向性	Lazar, J.	PDF	N/A	Directionality of two-photon absorption in representative fluorescent proteins
离散免疫抑制屏障的获得促进了从癌前病变到浸润性人类肺癌的起始和进展。	Yoffe, L.	PDF	N/A	Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer.
MaiZaic：一个强大的端到端流程，用于拼接自由飞行的农业领域航拍视频	Kharismawati, D. E.	PDF	N/A	MaiZaic: a robust end-to-end pipeline for mosaicking freely flown aerial video of agricultural fields
在神经元发育过程中，长时间尺度上的旋转稳定动力学逐渐显现。	Burrows, D. R.	PDF	N/A	Rotationally Stable Dynamics Over Long Timescales Emerge in Neuronal Development
在结直肠癌的侵袭性生物膜中，核梭杆菌（Fusobacterium nucleatum）的含量显著增加。	Queen, J.	PDF	N/A	Fusobacterium nucleatum is enriched in invasive biofilms in colorectal cancer
单核RNA测序揭示了死后间隔时间对小鼠大脑细胞组成和基因表达分析的影响。	yunxia, G.	PDF	N/A	Single-nucleus RNA sequencing revealed the impact of post-mortem interval on the cellular component and gene expression analysis of mouse brains
无交联剂的原位水凝胶诱导人牙髓干细胞自聚集，并增强其抗菌活性。	Lee, S. J.	PDF	N/A	Crosslinker-free in situ hydrogel induces self-aggregation of human dental pulp stem cells with enhanced antibacterial activity
当代HIV-1 C亚型在不同区域表现出独特的中和特性，针对最优秀的广谱中和抗体。	Sutar, J.	PDF	N/A	Distinct region-specific neutralization profiles of contemporary HIV-1 clade C against best-in-class broadly neutralizing antibodies
T细胞衍生的IFN-γ在病毒感染期间抑制滤泡辅助性T细胞分化和抗体反应	Sala, E.	PDF	N/A	T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses during Viral Infections
Clostridium novyi B型在野生亚洲象中引发致命的出血性疾病。	Padhi, S. K.	PDF	N/A	Clostridium novyi type B causes fatal hemorrhagic disease in wild Asian elephants
先前感染传染性法氏囊病病毒（IBDV）延长了某些鸡只从口咽腔排出野鸭H3N8甲型流感病毒（IAV）的时间，并增加了IAV样本中氨基酸替换的数量。	Nazki, S.	PDF	N/A	Prior infection with IBDV prolonged the shedding of a mallard H3N8 influenza A virus (IAV) challenge from the oropharyngeal cavity of some chickens and increased the number of amino acid substitutions in the IAV samples
SerRS通过液-液相分离（LLPS）被隔离，影响了局部翻译过程，并导致抗生素持久性的形成。	Zhang, Z.	PDF	N/A	Sequestration of SerRS through LLPS Impairs Localized Translation and Contributes to Antibiotic Persistence
回顾过往：先前的捕食风险经历并不决定群体中个体的反捕食反应	Rawat, K.	PDF	N/A	Peers over the past: Prior predation-risk experience does not dictate antipredator responses of individuals in groups
《埃塞俄比亚西北部南贡德尔地区食用大麦（Hordeum vulgare L.）的适应性与产量稳定性分析》	Worku, A. A.	PDF	N/A	Adaptability and yield stability analysis of food barley (Hordeum vulgare L.) in South Gondar zone, Northwest Ethiopia
五个模式物种中端粒到端粒基因组的填充区域基因组特征	Xiong, C.	PDF	N/A	Genomic feature of filled regions of telomere-to-telomere genomes in five model species
26S蛋白酶体中USP14调控底物降解的动力学模型	Wu, D.	PDF	N/A	A kinetic model for USP14 regulated substrate degradation in 26S proteasome
黄病毒劫持HuR以抑制CNPY3：免疫逃逸与治疗干预的新途径	Ding, X.	PDF	N/A	Flaviviruses Hijack HuR to Suppress CNPY3: A Novel Pathway for Immune Evasion and Therapeutic Intervention
一种含有从牛初乳中纯化的分泌组的新产品，Purasomes IRC100+，用于治疗阴道萎缩：体外研究评估其安全性和有效性	Salvaggio, A.	PDF	N/A	A new product containing secretome purified from bovine colostrum, Purasomes IRC100+, in the treatment of vaginal atrophy: in vitro study to evaluate safety and effectiveness
BORC通过马达蛋白UNC-104/KIF1A和UNC-116/KIF5来分离突触小泡和溶酶体蛋白。	Mathew, A.	PDF	N/A	BORC segregates synaptic vesicle and lysosomal proteins through motors UNC-104/KIF1A and UNC-116/KIF5
变暖增加了真核寄生浮游生物的丰富度并塑造了其群落结构	Rajarajan, A.	PDF	N/A	Warming increases richness and shapes assemblages of eukaryotic parasitic plankton
第三种类型的PETase来自海洋的Halopseudomonas谱系。	Turak, O.	PDF	N/A	A third type of PETase from the marine Halopseudomonas lineage
肽盘辅助的疏水聚类技术用于生产多聚体和多特异性纳米抗体蛋白	Duong, F.	PDF	N/A	Peptidisc-assisted hydrophobic clustering towards the production of multimeric and multispecific nanobody proteins
非核小体的 (CENP-A/H4)2 - DNA 复合物可能作为着丝粒组织的一个平台	Ali-Ahmad, A.	PDF	N/A	Non-nucleosomal (CENP-A/H4)2 - DNA complexes as a possible platform for centromere organization
通过人工智能驱动的迭代学习在蛋白质序列空间中进行高效搜索	Sanchez-Ruiz, J.	PDF	N/A	Efficient searches in protein sequence space through AI-driven iterative learning
非稀释结合理论及表面相分离在膜结合蛋白中的应用	Zhao, X.	PDF	N/A	Theory of non-dilute binding and surface phase separation applied to membrane-binding proteins
成熟的套索肽通过广泛存在的乙酰转移酶进行迭代酰化，以生产脂质套索肽。	Xiong, J.	PDF	N/A	Iterative acylation on mature lasso peptides by widespread acetyltransferases for lipolasso production
持久性烈性噬菌体存在于细菌分离物中。	Dougherty, P. E.	PDF	N/A	Persistent virulent phages exist in bacterial isolates
脂质组学揭示多能干细胞向神经和中胚层谱系分化过程中的细胞特异性变化	Odenkirk, M. T.	PDF	N/A	Lipidomics Reveals Cell Specific Changes During Pluripotent Differentiation to Neural and Mesodermal Lineages
发育中的突触修剪在小脑橄榄核环路中塑造预测性处理	Verma, S.	PDF	N/A	Developmental synaptic pruning in the olivo-cerebellar circuit sculpts predictive processing
婴儿早期的听觉通路成熟：与言语产生的关联	Liu, F.	PDF	N/A	Auditory tract maturation in early infancy: Links to speech production
GPNMB 是溶酶体功能障碍的生物标志物，并通过 LRRK2 调控的溶酶体胞吐作用分泌。	Bogacki, E. C.	PDF	N/A	GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
乙醇通过增加颅神经嵴细胞的凋亡，在Bmp突变体中诱导颅面缺陷，这一过程独立于nkx2.3的作用。	Vo, H. D. L.	PDF	N/A	Ethanol induces craniofacial defects in Bmp mutants independent of nkx2.3 by elevating cranial neural crest cell apoptosis
意外的D-统计量转向：为何应用于人类的D-统计量测量的是突变率变异而非尼安德特人基因渗入	Amos, W.	PDF	N/A	Unexpected D-tour Ahead: Why the D-Statistic, applied to Humans, Measures Mutation Rate Variation not Neanderthal Introgression
# BioRxiv 2024-12-31 Papers

标题	作者	PDF链接	代码仓库	Title
使用结构图嵌入进行快速蛋白质结构搜索	Greener, J. G.	PDF	N/A	Fast protein structure searching using structure graph embeddings
激酶IKK2的双特异性自磷酸化通过磷酸酶中间体使底物IκBα得以磷酸化。	Borar, P.	PDF	N/A	Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate
使用线性图像解码器和非线性噪声抑制技术从人类大脑活动中重建无语义的视觉图像	Li, Q.	PDF	N/A	Visual Image Reconstructed Without Semantics from Human Brain Activity Using Linear Image Decoders and Nonlinear Noise Suppression
KLP-19 控制着秀丽隐杆线虫（C. elegans）纺锤体中间区的微管长度，从而在有丝分裂过程中影响纺锤体动力学和力的传递。	Zimyanin, V.	PDF	N/A	KLP-19 controls microtubule length in the spindle midzone of C. elegans, affecting spindle dynamics and force transmission during mitosis.
FOXG1通过FGF信号通路在调控发育中新皮质胶质生成中的双重作用。	Bose, M.	PDF	N/A	Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway.
线粒体在轴突中的分布通过eIF2β在衰老过程中维持神经元自噬。	Shinno, K.	PDF	N/A	Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β
EGF/STAT1与IFNγ/NRF2信号通路之间的平衡调控ECM1表达并决定肝脏稳态与慢性肝病的关系	Li, Y.	PDF	N/A	Balance Between EGF/STAT1 and IFNγ/NRF2 Signaling Controls ECM1 Expression and Determines Hepatic Homeostasis versus Chronic Liver Disease
EGF/STAT1与IFNγ/NRF2信号通路之间的平衡调控ECM1表达并决定肝脏稳态与慢性肝病的发生	Li, Y.	PDF	N/A	Balance Between EGF/STAT1 and IFNγ/NRF2 Signaling Controls ECM1 Expression and Determines Hepatic Homeostasis versus Chronic Liver Disease
新型基因编码探针用于通过偏振显微镜进行细胞信号传导的功能成像	Miclea, P. S.	PDF	N/A	Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy
为纪念非洲-哥伦比亚音乐文化，将一种来自太平洋雨林的青蛙命名为Epipedobates currulao sp. nov.（无尾目：箭毒蛙科）。	Betancourth-Cundar, M.	PDF	N/A	Honoring the Afro-Colombian musical culture with the naming of Epipedobates currulao sp. nov. (Anura: Dendrobatidae), a frog from the Pacific rainforests
局部养分添加导致全球草地植物多样性丧失，但并未引起生物同质化。	Chen, Q.	PDF	N/A	Local nutrient addition drives plant biodiversity losses but not biotic homogenization in global grasslands
戊型肝炎病毒通过ORF2蛋白调节浆细胞样树突状细胞诱导的抗病毒反应	Joshi, G.	PDF	N/A	Hepatitis E Virus-induced antiviral response by plasmacytoid dendritic cells is modulated by the ORF2 protein
FinaleToolkit：利用高速计算工具包加速无细胞DNA片段分析	Li, J. W.	PDF	N/A	FinaleToolkit: Accelerating Cell-Free DNA Fragmentation Analysis with a High-Speed Computational Toolkit
磷酸饥饿诱导的CORNICHON同源物5作为内质网货物受体参与拟南芥中PHT1转运蛋白的运输	Chiu, C.-Y.	PDF	N/A	Phosphate Starvation-Induced CORNICHON HOMOLOG 5 as Endoplasmic Reticulum Cargo Receptor for PHT1 Transporters in Arabidopsis
使用语言模型模拟5亿年的进化历程	Hayes, T.	PDF	N/A	Simulating 500 million years of evolution with a language model
利用计算机化飞行磨研究栎树相关Agrilinae（鞘翅目：吉丁科）飞行性能的种内和种间差异	Le Souchu, E.	PDF	N/A	Intra- and interspecific variations in flight performance of oak-associated Agrilinae (Coleoptera: Buprestidae) using computerised flight mills
通过对海参再生肠道进行单细胞RNA测序，揭示了体腔上皮细胞的多能性。	Medina-Feliciano, J. G.	PDF	N/A	Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium
保守的ATP酶PCH-2通过抑制线虫（C. elegans）中交叉的形成，控制交叉的数量和分布。	Patel, B.	PDF	N/A	The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing their formation in C. elegans
在Slc29a3/Unc5b基因座中，由TAD边界破坏引起的转录变化的方向和模式取决于组织特异性的表观遗传背景。	Salnikov, P. A.	PDF	N/A	Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context
《编排不可能的化学反应：B12依赖性甲硫氨酸合成酶催化舞蹈的结构快照》

这篇标题描述了一项科学研究，该研究通过捕捉B12依赖性甲硫氨酸合成酶在催化过程中的结构变化，揭示了其复杂的化学反应机制。标题中的“编排不可能的化学反应”强调了这一过程的复杂性和精妙性，而“结构快照”则指通过实验手段获取的酶在不同催化阶段的三维结构图像。 | Mendoza, J. | PDF | N/A | Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography | | 尿液cf-核小体：窥探人体生理与疾病的无创窗口

这段翻译将“Urine cf-Nucleosomes”译为“尿液cf-核小体”，其中“cf”通常代表“cell-free”，即“无细胞的”，但在中文语境中，直接使用“cf”更为常见和简洁。“A Non-invasive Window into Human Physiology and Disease”则译为“窥探人体生理与疾病的无创窗口”，其中“Non-invasive”译为“无创的”，强调了这种检测方法的非侵入性特点，“Window”译为“窗口”，形象地表达了其作为观察和了解人体生理与疾病状态的途径。整个翻译保持了原文的科学性和准确性，同时符合中文的表达习惯。 | Lotem, M. | PDF | N/A | Urine cf-Nucleosomes: A Non-invasive Window into Human Physiology and Disease | | 在磷酸盐限制条件下，替代性脂质合成促进了革兰氏阴性ESKAPE病原菌的抗生素耐受性。 | Olea-Ozuna, R. J. | PDF | N/A | Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens | | 一个MEF2C转录因子网络调控糖尿病肾病中肾小球内皮细胞的增殖。 | Melo Ferreira, R. | PDF | N/A | A MEF2C transcription factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease | | X射线衍射揭示小鼠新皮层的周期性结构 | Murokh, S. | PDF | N/A | X-ray Diffraction Reveals Periodicity in Murine Neocortex | | 空间转录组分析揭示晚期卵巢透明细胞癌的上皮-间质梯度内肿瘤异质性 | Truong Le, T. | PDF | N/A | Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient | | 自注释质粒 | Hernandez, S. I. | PDF | N/A | Self-Documenting Plasmids | | 评估阿尔茨海默病中淀粉样蛋白β和Tau寡聚体的联合神经毒性：一种新的细胞水平标准 | Kuznetsov, A. V. | PDF | N/A | Evaluating the Combined Neurotoxicity of Amyloid Beta and Tau Oligomers in Alzheimer's Disease: A Novel Cellular-Level Criterion | | 使用冷冻电子断层扫描技术对染色质生物分子凝聚体进行定量空间分析 | Zhou, H. | PDF | N/A | Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography | | NFAT2通过利用MARCH8 E3连接酶在表观遗传景观上的差异，驱动了Orai3的转录和蛋白质降解。 | Raju, S. | PDF | N/A | NFAT2 drives both Orai3 transcription and protein degradation by harnessing the differences in epigenetic landscape of MARCH8 E3 ligase | | 用于晶体衍射数据质量评估的 I/σI 与 {Rmerg, Rmeas, Rpim, CC1/2} 的关系分析 | Fu, Z. | PDF | N/A | I/σI vs {Rmerg, Rmeas, Rpim, CC1/2} for Crystal Diffraction Data Quality Evaluation | | 对一种野生社会性哺乳动物的主要组织相容性复合体两类进行表征：以带状猫鼬为例 | Schubert, N. | PDF | N/A | Characterization of both major histocompatibility complex classes in a wild social mammal: the banded mongoose | | 主要组织相容性复合体多样性对社会性哺乳动物适应性的性别依赖性影响 | Schubert, N. | PDF | N/A | Sex-dependent influence of major histocompatibility complex diversity on fitness in a social mammal | | 复制压力增加了疟疾寄生虫基因组中的新生拷贝数变异（CNVs）。 | Brown, N. J. | PDF | N/A | Replication stress increases de novo CNVs across the malaria parasite genome | | 肼屈嗪通过抑制半胱胺双加氧酶来治疗先兆子痫和衰老性胶质母细胞瘤。 | Shishikura, K. | PDF | N/A | Hydralazine inhibits cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma | | 一个无菌损伤的微生理系统通过巨噬细胞衍生的细胞外囊泡相互作用展示了中性粒细胞的反向迁移。 | Babatunde, K. A. | PDF | N/A | A microphysiological system of sterile injury demonstrates neutrophil reverse migration via macrophage-derived extracellular vesicle crosstalk. | | GnT基序：长度大于或等于8个碱基对的短核苷酸序列，在细菌中能够使T:A到G:C的突变率增加超过1000倍。 | Horton, J. S. | PDF | N/A | GnT motifs: short nucleotide tracts of >=8bp that can increase T:A->G:C mutation rates >1000-fold in bacteria | | 供体链互补和钙离子协调驱动古菌纤毛的无伴侣蛋白聚合 | Sleutel, M. | PDF | N/A | Donor Strand Complementation and Calcium Ion Coordination Drive the Chaperone-free Polymerization of Archaeal Cannulae | | 一种细菌间的半胱氨酸蛋白酶毒素通过靶向II型DNA拓扑异构酶GyrB和ParE抑制细胞生长 | Song, P.-Y. | PDF | N/A | An Interbacterial Cysteine Protease Toxin Inhibits Cell Growth by Targeting Type II DNA Topoisomerases GyrB and ParE | | 基于成像的筛选方法鉴定出新型天然化合物，这些化合物能够干扰莱茵衣藻的细胞和叶绿体分裂。 | Clark-Cotton, M. R. | PDF | N/A | Imaging-based screen identifies novel natural compounds that perturb cell and chloroplast division in Chlamydomonas reinhardtii | | 解读新热带地区 Melanastera 属（半翅目：木虱总科：Liviidae）的多样化模式与时间 | Serbina, L. | PDF | N/A | Deciphering the patterns and timing of diversification of the genus Melanastera (Hemiptera: Psylloidea: Liviidae) in the Neotropics | | 重写线粒体疾病中的核表观遗传脚本作为控制异质性的策略 | Perez, M. J. | PDF | N/A | Rewriting nuclear epigenetic scripts in mitochondrial diseases as a strategy for heteroplasmy control | | 在KPP小鼠模型中，胰腺癌诱导的恶病质表现出性别特异性的生存差异，但并未观察到组织消耗的差异。 | Weinzierl, N. | PDF | N/A | Sex-specific survival but not tissue wasting in the KPP mouse model of pancreatic cancer-induced cachexia | | 双相情感障碍和精神分裂症风险基因AKAP11编码一种自噬受体，该受体将PKA激酶网络稳态的调节与突触传递相耦合。 | Lee, Y.-K. | PDF | N/A | Bipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmission | | 渗透压通过平行的化学感应和生物物理机制调控秀丽隐杆线虫的产卵行为 | Medrano, E. | PDF | N/A | Osmolarity regulates C. elegans egg-laying behavior via parallel chemosensory and biophysical mechanisms | | 脑电图揭示初学者与经验冥想者在Isha Kriya冥想中皮质变化的纵向试点研究

分析βB3-晶状体蛋白缺失后小鼠晶状体形态学和蛋白质组学异常

翻译说明： 1. "Analysis of" 翻译为“分析”。 2. "mouse lens" 翻译为“小鼠晶状体”。 3. "morphological and proteomic abnormalities" 翻译为“形态学和蛋白质组学异常”。 4. "following depletion of βB3-crystallin" 翻译为“βB3-晶状体蛋白缺失后”。

全基因组关联分析：在多样化的野生苹果种质中筛选对扩展青霉（Penicillium expansum）引起的采后蓝霉病的抗性

翻译说明： 1. Genome-Wide Associations 翻译为“全基因组关联分析”，这是一种用于研究基因与性状之间关系的统计方法。 2. Diverse Wild Apple Germplasm 翻译为“多样化的野生苹果种质”，指的是具有遗传多样性的野生苹果资源。 3. Postharvest Blue Mold Resistance 翻译为“采后蓝霉病抗性”，指的是苹果在采收后对蓝霉病的抵抗能力。 4. Penicillium expansum 是蓝霉病的病原菌，翻译为“扩展青霉”。

这段翻译将原文的标题进行了适当的调整，以符合中文的表达习惯，同时保留了原文的核心信息。具体来说： 1. "Supervised Spike Sorting" 翻译为 "监督式尖峰排序"，这是神经科学中常用的术语，指的是在有监督的情况下对神经元发放的尖峰信号进行分类和排序。 2. "Feasibility of Noisy Single-Electrode Extracellular Recordings" 翻译为 "在噪声单电极细胞外记录中的可行性研究"，强调了在噪声环境下使用单电极进行细胞外记录的可行性。 3. "Systematic Study of Human C-Nociceptors recorded via Microneurography" 翻译为 "基于微神经图记录的人类C-伤害感受器的系统性研究"，说明了研究对象是人类C-伤害感受器，并且是通过微神经图技术进行记录的。

证据表明，创伤后应激障碍的症状群由不同的网络支撑。

或者更详细地翻译为：

有证据表明，创伤后应激障碍的不同症状群背后存在独立的神经网络机制。

BioRxiv 2024-12-30 Papers

标题	作者	PDF链接	代码仓库	Title
一种在中枢神经系统全细胞膜片钳记录中可靠测量微型及自发性突触后电位/电流的新方法	Dervinis, M.	PDF	N/A	A novel method for reliably measuring miniature and spontaneous postsynaptic potentials/currents in whole-cell patch clamp recordings in the central nervous system
利用多功能蛋白质组学工具绘制GALNT1底物图谱	Saei, A. A.	PDF	N/A	Mapping the GALNT1 substrate landscape with versatile proteomics tools
对炎症反应元件的多物种分析揭示了转座元件对NF-κB结合的古老和谱系特异性贡献	Wang, L.	PDF	N/A	Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding
婚赠行为演化的通用模型	Charmouh, A. P.	PDF	N/A	A general model for the evolution of nuptial gift-giving
一个用于量化流感病毒mRNA核输出速率的统计框架。	Miura, M.	PDF	N/A	A statistical framework for quantifying the nuclear export rate of influenza viral mRNAs.
合成控制方法消除了在单细胞和空间转录组数据分析中因重复使用数据而产生的虚假发现。	Song, D.	PDF	N/A	Synthetic control removes spurious discoveries from double dipping in single-cell and spatial transcriptomics data analyses
将互惠网络从物种层面缩小到个体层面，揭示了植物种群内一致的互动生态位和角色。	Quintero, E.	PDF	N/A	Downscaling mutualistic networks from species to individuals reveals consistent interaction niches and roles within plant populations
由SARS-CoV-2 NSP6和SARS-CoV-2调控的miRNAs影响的大脑、心脏和肺部的通路：一项提示癌症发病率的计算机模拟研究	Chatterjee, S.	PDF	N/A	Pathways in the brain, heart, and lung influenced by SARS-CoV-2 NSP6 and SARS-CoV-2 regulated miRNAs: an in silico study hinting cancer incidence
顺铂对蛋白质磷酸化的重编程	Qi, L.	PDF	N/A	Cisplatin reprogramming of protein phosphorylation
《从土壤到地表：探索绿色基础设施对建筑环境中微生物群落的影响》	Mcgonigal, M.	PDF	N/A	From Soil to Surface: Exploring the Impact of Green Infrastructure on Microbial Communities in the Built Environment
《非适应性精子的扩散搜索建模：实证与计算洞察》	Brisard, B. M.	PDF	N/A	Modeling Diffusive Search by Non-Adaptive Sperm: Empirical and Computational Insights
从PacBio HiFi数据中估算基因转换片段长度和速率	Charmouh, A. P.	PDF	N/A	Estimating gene conversion tract length and rate from PacBio HiFi data
新型量子分析方法揭示了不同大小皮质锥体神经元之间兴奋性突触电量的平均守恒性。	Dervinis, M.	PDF	N/A	Novel quantal analysis method reveals conservation of average excitatory synaptic charge across cortical pyramidal neurons of different sizes
从无人机上记录的蝴蝶运动描绘了它们在野外的迁徙飞行行为。	de Margerie, E.	PDF	N/A	Butterfly movements recorded from a UAV depict migratory flight behaviour in the wild.
星形胶质细胞衍生的MFG-E8促进阿尔茨海默病小鼠模型中的小胶质细胞突触消除。	Sokolova, D.	PDF	N/A	Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models
原料和制造环境作为味噌微生物群落的决定因素。	Ito, K.	PDF	N/A	Raw materials and manufacturing environment as determinants of miso microbial community.
结构和功能证据支持将小鼠的高阶视觉区域重新定义为一个单一的V2区。	Rowley, D. P.	PDF	N/A	Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2
半球间和半球内的前庭信号来源对V1的影响	Bouvier, G.	PDF	N/A	Inter- and Intrahemispheric Sources of Vestibular Signals to V1
在刺激呈现之后：在自由观察过程中，对物体内部的持续注视不会重新唤起类别表征。	Auerbach-Asch, C. R.	PDF	N/A	Beyond stimulus onset: Ongoing fixations within an object do not re-evoke category representations during free-viewing.
通过对大量天然配对的人类抗体序列和结构数据的大规模分析，揭示了保守的重链/轻链接触区域以及种系偏好性。	Dudzic, P.	PDF	N/A	Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data.
singIST：一种用于疾病模型与人类之间单细胞转录组学比较的综合方法	Moruno-Cuenca, A.	PDF	N/A	singIST: an integrative method for comparative single-cell trancriptomics between disease models and humans
JMJD6与YBX1发生物理相互作用并调控HOTAIR近端启动子	Gupta, A.	PDF	N/A	JMJD6 and YBX1 physically interact and regulate HOTAIR proximal promoter
大豆根质外体蛋白质组分析结合AlphaFold预测揭示了大豆炭疽病菌（Macrophomina phaseolina）的侵染策略及工程抗性的潜在靶点

这段文字可以翻译为：“致癌基因KRAS的转录剂量驱动肺腺癌细胞状态、进展和转移。” 其中，“Transcriptional Dosage”指的是基因转录的剂量或水平，“Oncogenic KRAS”是指具有致癌潜能的KRAS基因，“Drives”表示驱动或促使，“Lung Adenocarcinoma”是肺腺癌，“Cell States”指细胞的状态，“Progression”表示疾病的进展，“Metastasis”则是指癌症的转移。 | Serresi, M. | PDF | N/A | Transcriptional Dosage of Oncogenic KRAS Drives Lung Adenocarcinoma Cell States, Progression and Metastasis | | 癌症 vs. 对话式人工智能 | Kawchak, K. | PDF | N/A | Cancer vs. Conversational Artificial Intelligence | | 小分子反向激动剂VUF16840对非典型趋化因子受体ACKR3的组成型活性的抑制。 | Bosma, R. | PDF | N/A | Inhibition of constitutive activity of the atypical chemokine receptor ACKR3 by the small-molecule inverse agonist VUF16840 | | 直接RNA牛津纳米孔测序技术能够区分tRNA中U34位点的修饰。 | Kusmirek, W. | PDF | N/A | Direct RNA Oxford Nanopore sequencing distinguishes between modifications in tRNA at the U34 position | | H3K4-H3K9组蛋白甲基化模式与癌胎发育网络作为儿童高级别胶质瘤细胞命运决定的驱动因素 | Uthamacumaran, A. | PDF | N/A | H3K4-H3K9 Histone Methylation Patterns and Oncofetal Developmental Networks as Drivers of Cell Fate Decisions in Pediatric High-Grade Gliomas | | 猴子在路径规划任务中背侧前运动皮层与集合相关神经活动的多样性 | Sakamoto, K. | PDF | N/A | Diversity of set-related neuronal activity in the dorsal premotor cortex of monkeys during a path-planning task | | 不同认知状态下健康老年人认知储备的电生理相关性 | Zhunussova, A. | PDF | N/A | Electrophysiological correlates of cognitive reserve in healthy older adults at different cognitive states | | 研究感觉运动空间依赖性在塑造对虚拟3D物体的意识访问中的作用 | Motyka, P. | PDF | N/A | Investigating the role of sensorimotor spatial dependencies in shaping conscious access to virtual 3D objects | | 在猕猴的颞上沟中，头部和身体方向的整合特异地针对直立的身体。 | Zafirova, Y. | PDF | N/A | Integration of head and body orientations in the macaque superior temporal sulcus is specific to upright bodies | | 小鼠大脑中转录组、形态学和电生理学细胞类型密度的定量空间图谱 | Veraszto, C. | PDF | N/A | A quantitative spatial atlas of transcriptomic, morphological, and electrophysiological cell type densities in the mouse brain | | Layilin调节皮肤中调节性T细胞的运动性和抑制能力 | Gouirand, V. | PDF | N/A | Layilin Regulates Treg Motility and Suppressive Capacity in Skin | | 一种基于第四代完全删除腺病毒载体的强效大流行禽流感病毒疫苗 | Qi, Y. | PDF | N/A | A Potent Pandemic Avian Influenza Virus Vaccine Based on a 4th Generation Fully Deleted Adenoviral Vector | | 免疫细胞单细胞RNA测序分析揭示了一种与年龄相关的T细胞亚群与症状性良性前列腺增生的关联。 | Broman, M. | PDF | N/A | Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia | | 一个无菌损伤的微生理系统通过巨噬细胞来源的细胞外囊泡的相互作用展示了中性粒细胞的反向迁移。 | Babatunde, K. A. | PDF | N/A | A microphysiological system of sterile injury demonstrates neutrophil reverse migration via macrophage-derived extracellular vesicle crosstalk. | | 单细胞RNA测序结合TCR测序揭示小鼠淋巴和非淋巴组织中双TCR Treg细胞的比例及特性 | Xu, Y. | PDF | N/A | scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues | | 开发一种针对鸭IFN-γ蛋白的单克隆抗体及其在细胞内细胞因子染色中的应用 | Chen, Y. | PDF | N/A | Development of a monoclonal antibody against duck IFN-γ protein and the application for Intracellular Cytokine Staining | | 镉的摄入不会破坏亚社会性昆虫幼体间微生物群落的社会传播。 | Cheutin, M.-C. | PDF | N/A | Cadmium ingestion does not disrupt the social transmission of the microbiome in juveniles of a subsocial insect | | 在无症状的旱季感染期间，恶性疟原虫（Plasmodium falciparum）表达的var基因数量较少，且表达水平低于临床疟疾病例。 | Ceesay, S. | PDF | N/A | Plasmodium falciparum expresses fewer var genes at lower levels during asymptomatic dry season infections than clinical malaria cases | | 原生生物作为复杂微生物和病毒关联的媒介 | Schulz, F. | PDF | N/A | Protists as mediators of complex microbial and viral associations | | 利用CRISPR-Cas技术快速鉴定诊断样本中的非洲猪瘟病毒 | Kambakam, S. | PDF | N/A | Rapid identification of African swine fever virus in diagnostic samples using CRISPR-Cas | | 从不同环境中分离自蟑螂（德国小蠊）的大肠杆菌的抗菌素耐药性、致病性和毒力模式：一个公共卫生问题 | Sigma, S. H. | PDF | N/A | Antimicrobial resistance, pathogenicity and virulence patterns of Escherichia coli isolated from cockroaches (Blattella germanica) across diverse environments: a public health concern | | GnT基序：长度大于或等于8个碱基对的短核苷酸序列，在细菌中能够使T-G:C突变率提高超过1000倍。 | Horton, J. S. | PDF | N/A | GnT motifs: short nucleotide tracts of greater than or equal to 8bp that can increase T-G:C mutation rates >1000-fold in bacteria | | 非孟德尔染色体传递和不寻常的性别决定是否会影响蝇类Bradysia coprophila中的雄性择偶行为？ | Hodson, C. N. | PDF | N/A | Does non-Mendelian chromosome transmission and unusual sex determination affect male mate choice in the fly Bradysia coprophila? | | 野外种群反应规范预测中的变量误差与验证问题 | Ergon, R. | PDF | N/A | Errors-in-variables and validation problems in reaction norm predictions for wild populations | | MicroRNA分析揭示了成年果蝇肠道干细胞功能的新型调控因子。 | Sreejith, P. | PDF | N/A | MicroRNA profiling identifies novel regulators of stem cell function in the adult Drosophila intestine. | | 靶向GSK-β的肽类抑制剂：阿尔茨海默病干预的合理计算策略 | Zareei, S. | PDF | N/A | Targeting GSK-beta with Peptide Inhibitors: A Rational Computational Strategy for Alzheimer's Disease Intervention | | YnaI展示了小电导机械敏感通道中结构门控机制的多样性。 | Flegler, V. J. | PDF | N/A | YnaI exemplifies the diversity of structural gating mechanisms in mechanosensitive channels of small conductance | | 探索合成数据生成在髓母细胞瘤亚组边界研究中的应用 | Prol-Castelo, G. | PDF | N/A | Exploring the Boundaries of Medulloblastoma Subgroups with Synthetic Data Generation | | 基于图网络的疾病-基因-药物关联分析：零样本疾病-药物预测及分析策略 | Liu, Y. | PDF | N/A | Graph Network-Based Analysis of Disease-Gene-Drug Associations: Zero-Shot Disease-Drug Prediction and Analysis Strategies | | 单细胞分析揭示了乙型肝炎病毒阳性（HBV-positive）与乙型肝炎病毒阴性（HBV-negative）肝细胞癌（HCC）病例中不同的免疫特征。 | Liu, K. | PDF | N/A | Single-cell analysis reveals distinct immune characteristics of hepatocellular carcinoma in HBV-positive versus HBV-negative cases | | 人类胰岛素降解酶构象动力学的表征与调控以控制酶活性 | Mancl, J. M. | PDF | N/A | Characterization and modulation of human insulin degrading enzyme conformational dynamics to control enzyme activity | | 评估过表达Ld_ζ1结构域的多诺瓦利什曼原虫活体在实验性人类内脏利什曼病中的免疫药理学保护效果 | Bansal, R. | PDF | N/A | Evaluation of Immunopharmacological Efficacy of Live Leishmania donovani Overexpressing Ld_ζ1domain for Protection Against Experimental Human Visceral Leishmaniasis | | CCT-217：一种具有里程碑意义的基因沉默疗法，用于减肥，通过促进脂肪褐变，增强瘦体重比例，减少内脏和皮下脂肪，并恢复肥胖患者的代谢健康。 | Reddy, R. | PDF | N/A | CCT-217: A Landmark Gene Silencing Therapeutic for Weight Loss That Enhances Lean Mass Composition, Reduces Visceral, Subcutaneous Fat and Restores Metabolic Health in Obesity through Browning | | 全面评估模拟禁食饮食：唾液代谢物谱、体重减轻及生物标志物分析 | Hof, K. S. | PDF | N/A | Comprehensive Assessment of a Fasting-Mimicking Diet: Salivary Metabolite Profiles, Weight Loss, and Biomarker Analysis | | 将致癌信号重定向至RNA载体复制以治疗转移性癌症 | Lin, M. Z. | PDF | N/A | Rewiring oncogenic signaling to RNA vector replication for the treatment of metastatic cancer | | 奖励与惩罚敏感性的可分离神经功能和分子特征 | Xu, T. | PDF | N/A | Dissociable neurofunctional and molecular characterizations of reward and punishment sensitivity | | 乳腺癌重塑前哨淋巴结中的淋巴管 | Eichin, D. | PDF | N/A | Breast Cancer Remodels Lymphatics in Sentinel Lymph Nodes | | 转录动态揭示BNIP3在果蝇肌肉重塑过程中线粒体自噬的作用

LC-MS/MS 表征 SOBERANA(R)02，一种针对 SARS-CoV-2 的受体结合域-破伤风类毒素结合疫苗

翻译说明： - LC-MS/MS：液相色谱-串联质谱法，是一种用于分析复杂混合物的技术。 - SOBERANA(R)02：疫苗名称，保留原文。 - receptor binding domain-tetanus toxoid conjugate vaccine：受体结合域-破伤风类毒素结合疫苗，描述了疫苗的组成和作用机制。 - against SARS-CoV-2：针对 SARS-CoV-2，说明了疫苗的目标病毒。

希望这个翻译对您有帮助！ | Martinez, O. | PDF | N/A | LC-MS/MS characterization of SOBERANA(R)02, a receptor binding domain-tetanus toxoid conjugate vaccine against SARS-CoV-2 | | 核苷酸编码调控着Lis1解除动力蛋白自抑制的能力。 | Geohring, I. C. | PDF | N/A | A nucleotide code governs Lis1's ability to relieve dynein autoinhibition | | Nde1促进Lis1与全长自抑制状态的人源Dynein-1的结合 | Yang, J. | PDF | N/A | Nde1 Promotes Lis1 Binding to Full-Length Autoinhibited Human Dynein-1 | | 通过尿液蛋白质组探索二甲双胍对人体的影响 | Chen, Y. | PDF | N/A | Exploring the effects of metformin on the body by urine proteome | | 有效马尔可夫动力学方法解决随机基因表达的非马尔可夫动力学 | Li, Y. | PDF | N/A | Effective Markovian dynamics method of solving non-Markovian dynamics of stochastic gene expression | | RhoBAST RNA适配体实现环开启荧光的结构基础。 | Siwik, S. H. | PDF | N/A | Structural basis for ring-opening fluorescence by the RhoBAST RNA aptamer. | | 推断病毒准种的方法：个体样本比较分析。 | Gregori, J. | PDF | N/A | Inference with Viral Quasispecies. Methods for Individual Samples Comparative Analysis. | | TCPGdb：一个全面的T细胞扰动基因组学数据库，用于识别关键的T细胞调控因子 | Dong, C. | PDF | N/A | TCPGdb: A comprehensive T cell perturbation genomics database for identification of critical T cell regulators | | 局部应力与长程应力在果蝇胚胎头沟形成中的作用 | Niloy, R. A. | PDF | N/A | The role of local and long-range stresses in cephalic furrow formation in the Drosophila melanogaster embryo | | 用于评估合成基因电路的线性混合效应模型 | Partipilo, G. | PDF | N/A | A Linear Mixed Effects Model for Evaluating Synthetic Gene Circuits | | 神经退行性和神经发育性作用：大分子脂质转运蛋白VPS13A和BLTP2在运动障碍中的角色 | Neuman, S. D. | PDF | N/A | Neurodegenerative and neurodevelopmental roles for bulk lipid transporters VPS13A and BLTP2 in movement disorders | | 在最近出现的携带NSP6中L260F突变的SARS-CoV-2变体中，RNA复制和致病性得到了增强。 | Taha, T. Y. | PDF | N/A | Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6 | | 深度学习模型用于从微CT成像中精确分割果蝇大脑

在这项研究中，我们开发了一种基于深度学习的模型，专门用于从微CT（计算机断层扫描）成像数据中精确分割果蝇（Drosophila melanogaster）的大脑。该模型结合了先进的卷积神经网络（CNN）架构，能够高效地处理三维图像数据，并准确地识别和分割出果蝇大脑的复杂结构。通过大量的训练数据和优化算法，我们的模型在多个评估指标上均表现出色，为神经科学研究提供了一种强大的工具，有助于更深入地理解果蝇大脑的解剖和功能。 | McDaniel, J. F. | PDF | N/A | A Deep Learning Model for Accurate Segmentation of the Drosophila melanogaster Brain from Micro-CT Imaging | | 冷大气等离子体在生物打印的三维肿瘤微环境模型中选择性破坏乳腺癌生长 | Bouret, L. M. | PDF | N/A | Cold Atmospheric Plasma Selectively Disrupts Breast Cancer Growth in a Bioprinted 3D Tumor Microenvironment Model |

BioRxiv 2024-12-29 Papers

标题	作者	PDF链接	代码仓库	Title
小脑将输入数据转换为具有空间维度的超低分辨率颗粒细胞编码：一个假设	Gilbert, M.	PDF	N/A	The Cerebellum Converts Input Data Into A Hyper Low-Resolution Granule Cell Code With Spatial Dimensions: A Hypothesis
你的影响力巨大的科学工作并未得到足够的认可。	Arabi, S.	PDF	N/A	You do not receive enough recognition for your influential science
分析校内与校外资助机制的比较优势	Zheng, X.	PDF	N/A	Analysis of the comparative strengths of intramural and extramural grant funding mechanisms
亚细胞空化气泡在超声诱导的细胞消融中引发细胞机械性溶解和集体伤口愈合	Bai, Z.	PDF	N/A	Subcellular Cavitation Bubbles Induce Cellular Mechanolysis and Collective Wound Healing in Ultrasound-Inflicted Cell Ablation
基于GWAS的数据整合与非编码CRISPRi筛选揭示骨密度的遗传病因	Conery, M.	PDF	N/A	GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density
在羊膜动物原肠胚形成过程中，左右组织者形成之前，双侧细胞流动显示出不对称性。	Asai, R.	PDF	N/A	Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation
SLAYER：一种通过整合分析癌症依赖性来识别合成致死相互作用的计算框架	Cohen, Z.	PDF	N/A	SLAYER: A Computational Framework for Identifying Synthetic Lethal Interactions through Integrated Analysis of Cancer Dependencies
工作记忆影响运动计时，但不影响感知计时。	Farajzadeh, M.	PDF	N/A	Working memory affects motor, but not perceptual timing
小脑学习理论：基于脉冲的连续时空强化学习	Kuriyama, R.	PDF	N/A	A theory of cerebellar learning as a spike-based reinforcement learning in continuous time and space
化学亚基和连接的多样性：微生物丰富性、微生物群相互作用及底物利用的关键分子决定因素	McCullough, H. C.	PDF	N/A	Diversity in Chemical Subunits and Linkages: A Key Molecular Determinant of Microbial Richness, Microbiota Interactions, and Substrate Utilization
现代人类与尼安德特人中心理特征的进化与文化发展相关联	Moriya, Y.	PDF	N/A	Evolution of mental traits linked to cultural development in modern humans and Neanderthals
玉米细胞类型特异性顺式调控的遗传结构	Marand, A. P.	PDF	N/A	The genetic architecture of cell-type-specific cis-regulation in maize
邻苯二甲酸酯暴露对水生生态毒理学模型系统中的交配行为和精子形态产生影响。	Guevara, B. L.	PDF	N/A	Phthalate exposure influences mating behavior and sperm morphology in an aquatic ecotoxicology model system
PL35家族糖胺聚糖裂解酶的晶体结构及超广谱底物的催化机制	Wei, L.	PDF	N/A	Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum
计算解剖学：小脑微区的计算，一个假设	Gilbert, M.	PDF	N/A	Computational anatomy: the cerebellar microzone computation, a hypothesis
Rho/Rok依赖的肌动球蛋白收缩性在三细胞连接处的调控限制了果蝇上皮的通透性。	Jacobs, T.	PDF	N/A	Rho/Rok-dependent regulation of actomyosin contractility at tricellular junctions restricts epithelial permeability in Drosophila
1001G+项目：一个精心筛选的拟南芥长读长基因组组装集合，旨在推动植物研究进展	Alonso-Blanco, C. C.	PDF	N/A	The 1001G+ project: A curated collection of Arabidopsis thaliana long-read genome assemblies to advance plant research
ThermoPlex：一种基于DNA热力学的目标特异性多重PCR引物自动设计工具	Agmata, A.	PDF	N/A	ThermoPlex: An Automated Design Tool for Target-specific Multiplex PCR Primers based on DNA Thermodynamics
视觉迫近反应的可塑性揭示了先天与后天成分的分离	Conway, P. B.	PDF	N/A	Plasticity of visual looming response reveals a dissociation of innate and learned components
负反馈在多芽酵母中平衡了极性位点。	Crocker, A. W.	PDF	N/A	Negative feedback equalizes polarity sites in a multi-budding yeast
Arp2/3复合体维持表皮朗格汉斯细胞的基因组完整性和生存能力。	Delgado, M.-G.	PDF	N/A	The Arp2/3 complex maintains genome integrity and survival of epidermal Langerhans cells
通过类似PROTAC的诱导剂消除侵袭性癌症的铁死亡	Oknin-Vaisman, A.	PDF	N/A	Eliminating Aggressive Cancers via PROTAC-like Inducers of Ferroptosis
利用牛奶来源的小细胞外囊泡口服递送司美鲁肽和替西帕肽	Zhang, Y.	PDF	N/A	Oral delivery of semaglutide and tirzepatide using milk-derived small extracellular vesicles
暂时停止矿物磷的供应会减少成年蛋鸡体内可动员的骨锌，无论其日粮中的锌供应量如何。	Lucke, A.	PDF	N/A	Temporary suspension of mineral phosphorus reduces mobilizable bone zinc in adult laying hens irrespective of the dietary zinc supply
中更新世过渡期间东地中海远洋生态系统对海水条件变化的响应	Agiadi, K.	PDF	N/A	Pelagic ecosystem responses to changes in seawater conditions during the Middle Pleistocene Transition in the Eastern Mediterranean
数学规划与图神经网络揭示疾病中通路的功能异质性	Triantafyllidis, C.	PDF	N/A	Mathematical Programming and Graph Neural Networks illuminate functional heterogeneity of pathways in disease
牛胚胎干细胞的胚胎与胚胎外分化可塑性	Su, Y.	PDF	N/A	Bovine Formative Embryonic Stem Cell Plasticity in Embryonic and Extraembryonic Differentiation
利用机器学习和加速度测量技术对动物行为进行分类，并评估不确定性	Agarwal, M.	PDF	N/A	Leveraging machine learning and accelerometry to classify animal behaviours with uncertainty
永久冻土融化后的不同水文条件导致了微生物群落组成的显著差异。	Waqas, M.	PDF	N/A	Different hydrological conditions after permafrost thaw result in distinct microbial community compositions
冬季温度对一种向北扩张的蜘蛛的冷适应种群的影响：生存、能量储存及差异基因表达	Ortiz Movliav, C.	PDF	N/A	Winter temperature effects in a cold-adapted northern population of a range-expanding spider: survival, energy stores, and differential gene expression
栖息地复杂性塑造了全球生物与社会景观	Cant, J.	PDF	N/A	Habitat complexity defines global biological and societal landscapes
通过海洋传播实现陆生植物的全球分布	Vatanparast, M.	PDF	N/A	Global distribution of a land plant by means of oceanic dispersal
对人类视网膜表观基因组和三维染色质结构的单细胞分析	Yuan, Y.	PDF	N/A	Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina
KRAS G12D突变中的动态耦合与熵变：分子灵活性、变构效应与功能的深入解析	Hacisuleyman, A.	PDF	N/A	Dynamic Coupling and Entropy Changes in KRAS G12D Mutation: Insights into Molecular Flexibility, Allostery and Function
使用图集成神经网络寻找与多种生物医学结果相关的显著多组学相互作用网络	Chan, J.	PDF	N/A	Finding Salient Multi-Omic Interactomes Relevant to Multiple Biomedical Outcomes using Graph Ensemble Neural Networks
开发一种高通量3D培养微流控平台，用于患者来源类器官的多参数表型和组学分析	Botrugno, O. A.	PDF	N/A	Development of a high-throughput 3D culture microfluidic platform for multi-parameter phenotypic and omics profiling of patient-derived organoids
内分泌抵抗性雌激素受体阳性乳腺癌中的代谢转换	Brechbuhl, H. M.	PDF	N/A	Metabolic Switch in Endocrine Resistant Estrogen Receptor Positive Breast Cancer
进化上保守的相互衰老和肿瘤抑制信号限制了终身癌症的发生。	Liu, L.	PDF	N/A	Evolutionary conserved reciprocal senescence and tumor suppressor signals limit lifetime cancer
表观遗传紊乱驱动干性、衰老逃逸和肿瘤异质性	Magnani, E.	PDF	N/A	Epigenetic Disordering Drives Stemness, Senescence Escape and Tumor Heterogeneity
JMJD6与YBX1发生物理相互作用并调控HOTAIR近端启动子	Gupta, A.	PDF	N/A	JMJD6 and YBX1 physically interact and regulate HOTAIR proximal promoter
Goliath克隆群和体内克隆动态追踪揭示了紫外线诱导皮肤癌发生的三个阶段	Avdieiev, S.	PDF	N/A	Goliath clades and in vivo tracking of clonal dynamics show three phases of UV-induced skin carcinogenesis
抑制细胞外基质蛋白fibulin-3可以减少肿瘤干细胞中的免疫抑制信号，并增强巨噬细胞对胶质母细胞瘤的活化作用。	Kundu, S.	PDF	N/A	Inhibition of the extracellular matrix protein fibulin-3 reduces immunosuppressive signaling in tumor stem cells and increases macrophage activation against glioblastoma
局部应用碳点和介孔二氧化硅纳米颗粒衍生的dsRNA纳米复合材料以控制甜菜卷顶病毒和芜菁花叶病毒	Zarrabi, S.	PDF	N/A	Topical application of carbon dots and mesoporous silica nanoparticle-derived dsRNA-nanocomposites for the control of beet curly top virus and turnip mosaic virus
在红球菌（Rhodococcus ruber）R1中的苯胺双加氧酶：关于粪臭素降解的深入解析	Galaz, S. J.	PDF	N/A	Aniline Dioxygenase in Rhodococcus ruber R1: Insights into Skatole Degradation
在南设得兰群岛（South Shetland Islands）的南极地区，从一只黑背鸥（Larus dominicanus）中分离出了高致病性禽流感病毒（HPAIV）H5N1分支2.3.4.4b。	Ogrzewalska, M.	PDF	N/A	High Pathogenicity Avian Influenza Virus (HPAIV) H5N1 clade 2.3.4.4b recovered from a kelp gull (Larus dominicanus) in the South Shetland Islands, Antarctica
基于定量荧光内窥镜探针评估的光触发脂质体阿霉素的辐照度依赖性动力学	Rohrbach, D. J.	PDF	N/A	Fluence rate-dependent kinetics of light-triggered liposomal doxorubicin assessed by quantitative fluorescence-based endoscopic probe
通过基于定量荧光的内窥镜探针评估光触发脂质体阿霉素的荧光速率依赖性动力学。	Rohrbach, D. J.	PDF	N/A	Fluence rate-dependent kinetics of light-triggered liposomal doxorubicin assessed by quantitative fluorescence-based endoscopic probe
利用统计去卷积模型描绘细胞类型特异性干性的空间模式	Li, E. J.	PDF	N/A	Delineating the Spatial Patterns of Cell Type-Specific Stemness Using a Statistical Deconvolution Model
QC4Metabolomics：代谢组学数据的实时与回顾性质量控制	Stanstrup, J.	PDF	N/A	QC4Metabolomics: Real-time and Retrospective Quality Control of Metabolomics Data
分子毒性的（α, β）-k布尔特征：以微囊藻毒素为例	Moscato, P.	PDF	N/A	The (α, β)-k Boolean Signatures of Molecular Toxicity: Microcystin as a Case Study
高维随机变量的互信息：基于前沿互信息的估计	Mori, T.	PDF	N/A	Mutual information of high-dimensional random variables: estimation by frontier mutual information
在外周神经鞘瘤模型中，神经鞘瘤的放射治疗直接引发的抗肿瘤反应以及远隔效应（abscopal effect）与抗PD1治疗协同作用，共同对抗前庭神经鞘瘤。	Yin, Z.	PDF	N/A	Direct and abscopal anti-tumor responses elicited by peripheral nerve schwannoma irradiation synergize with anti-PD1 treatment in vestibular schwannoma models
在前庭神经鞘瘤模型中，联合使用免疫检查点抑制剂和抗VEGF疗法实现了增强的肿瘤控制和听力损失预防。	Lu, S.	PDF	N/A	Enhanced Tumor Control and Hearing Loss Prevention Achieved with Combined Immune Checkpoint Inhibitor and Anti-VEGF Therapy in Vestibular Schwannoma Model
运动学习与分带行走中适应性内外侧控制的节省	Nyangau, N. M.	PDF	N/A	Motor Learning And Savings Of Adaptive Mediolateral Control During Split-Belt Walking
《向日葵瘦果休眠释放的生物物理边界》。	Arata, G. J.	PDF	N/A	Biophysical boundaries for dormancy release in sunflower achenes.
PIF4基因表达的阈值依赖性负自反馈调控优化了拟南芥的生长和适应性。	Das, S.	PDF	N/A	Threshold-dependent negative autoregulation of PIF4 gene expression optimizes growth and fitness in Arabidopsis
转录组分析揭示，马铃薯Y病毒的媒介吸引力是通过对萜烯合成酶1（TPS1）的时间调控来介导的。	Nihranz, C. T.	PDF	N/A	Transcriptomic analysis reveals vector attraction to potato virus Y is mediated through temporal regulation of TERPENE SYNTHASE 1 (TPS1)
条形码技术推断的浅水印度-太平洋区系海绵生物多样性	Erpenbeck, D.	PDF	N/A	Barcoding-inferred biodiversity of shallow-water Indo-Pacific demosponges
人类滑倒控制：探讨手部加速度调节在预防滑倒中的作用	Nazari, K.	PDF	N/A	Human Slip Control: Investigating the Role of Hand Acceleration Modulation in Preventing Slips
小鼠运动中的速度控制的运动单元机制	Thomas, K.	PDF	N/A	Motor unit mechanisms of speed control in mouse locomotion
这段话可以翻译为：“由注意而非预期的神经机制，通过概率性提示来主导空间选择。”

解释： - Neural mechanisms of attention：注意的神经机制 - not expectation：而非预期 - govern：主导、控制 - spatial selection：空间选择 - probabilistic cueing：概率性提示

在裸鳃类动物Caloria militaris中，对钵水母幼体的捕食及选择性刺丝囊的摄取动态

翻译说明： - "Predation" 翻译为 "捕食" - "scyphozoan polyps" 翻译为 "钵水母幼体"（钵水母是水母的一个纲，polyps 指其幼体阶段） - "selective nematocyst incorporation dynamics" 翻译为 "选择性刺丝囊的摄取动态"（nematocyst 是刺丝囊，水母等生物用于捕食和防御的细胞器） - "aeolid" 翻译为 "裸鳃类动物"（aeolid 是一类海蛞蝓） - "Caloria militaris" 是物种的拉丁学名，保留不变。 | Dror, H. | PDF | N/A | Predation on scyphozoan polyps and selective nematocyst incorporation dynamics in the aeolid, Caloria militaris | | 通过结合AlphaFold预测的大豆根质外体蛋白质组分析揭示了Macrophomina phaseolina的感染策略及工程抗性的潜在靶点 | Veeraganti Naveen Prakash, C. | PDF | N/A | Proteome Analysis of Soybean Root Apoplast Combined with AlphaFold Prediction Reveal Macrophomina phaseolina Infection Strategies and Potential Targets for Engineering Resistance | | 饮食中胆固醇升高导致的肝内晶体足以使肝脏变硬。 | Li, D. | PDF | N/A | Intrahepatic crystals from elevated dietary cholesterol are sufficient to stiffen the liver | | 在1型糖尿病的发病机制中，β细胞功能障碍的发生与胰岛炎无关。 | Huber, M. K. | PDF | N/A | Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis | | 在Shank3自闭症小鼠模型中，初级感觉神经元功能障碍导致机械性瘙痒敏感性增强 | Huzard, D. | PDF | N/A | Primary sensory neuron dysfunction underlying mechanical itch hypersensitivity in a Shank3 mouse model of autism | | SynDIG4/PRRT1的缺失会改变AMPA受体在Rab4和Rab11阳性内体中的分布，并损害基础AMPA受体的再循环。 | He, C.-W. | PDF | N/A | Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling. | | 通过调节核质运输来控制自我扩增RNA疫苗的反应原性，同时保持其免疫原性。 | Wojcechowskyj, J. A. | PDF | N/A | Controlling reactogenicity while preserving immunogenicity from a self-amplifying RNA vaccine by modulating nucleocytoplasmic transport | | 在产后乳腺退化过程中诱导衰老有助于组织重塑并促进产后肿瘤发生 | li, H. | PDF | N/A | Induction of Senescence During Postpartum Mammary Gland Involution supports tissue remodeling and promotes postpartum tumorigenesis | | 线粒体棕色脂肪组织维持因子Nipsnap1直接与β-氧化蛋白机制相互作用。 | Tsai, P.-Y. | PDF | N/A | The Mitochondrial Brown Adipose Tissue Maintenance Factor Nipsnap1 Interfaces Directly with the Beta-Oxidation Protein Machinery. | | 穆勒氏棘轮与基因复制 | Freund, F. | PDF | N/A | Muller's Ratchet and Gene Duplication | | 通过控制多基因背景效应识别QTL与环境互作 | Zhao, F. | PDF | N/A | Identification of QTL-by-Environment Interaction by Controlling Polygenic Background Effect | | 共祖关系叠加在混合群体上，可以在个体水平分辨率上衡量亲缘关系。 | Chen, D. | PDF | N/A | Coancestry superposed on admixed populations yields measures of relatedness at individual-level resolution | | 使用ResidPCA在单细胞RNA和ATAC测序数据中发现疾病相关的细胞状态 | Carver, S. | PDF | N/A | Discovery of disease-associated cellular states using ResidPCA in single-cell RNA and ATAC sequencing data | | 通过19F NMR表征蛋白质中酪氨酸环的翻转 | Lu, M. | PDF | N/A | Characterizing Tyrosine Ring Flips in Proteins by 19F NMR |

BioRxiv 2024-12-28 Papers

标题	作者	PDF链接	代码仓库	Title
如何利用转录组数据进行癌症治疗诱导耐药性的博弈论建模？以患者来源的胶质母细胞瘤类器官为例	Spekking, L.	PDF	N/A	How to use transcriptomic data for game-theoretic modeling of treatment-induced resistance in cancer cells? A case study in patient-derived glioblastoma organoids
自适应学习的物理感知光场显微镜技术实现了对三维亚细胞动态的长时间（全天）和毫秒级超分辨率成像。	Zhu, L.	PDF	N/A	Adaptive-learning physics-aware light-field microscopy enables day-long and millisecond-scale super-resolution imaging of 3D subcellular dynamics
利用深度学习方法从单个神经元放电序列推断可塑性规则	Wang, X.	PDF	N/A	Inferring plasticity rules from single-neuron spiketrains using deep learning methods
视觉感知学习的不对称转移由几何不变性的稳定性决定。	Yang, Y.	PDF	N/A	The asymmetric transfers of visual perceptual learning determined by the stability of geometrical invariants
eIF2β与eIF5、eIF2B及5MP1相互作用的分子基础及其受CK2调控的机制	Wagner, P. A.	PDF	N/A	Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2
尽管存在竞争，但仍能共存：植被结构复杂性在演替过程中塑造了苔藓植物的多样性。	Hanusch, M.	PDF	N/A	Coexistence despite competition: Vegetation structural complexity shapes bryophyte diversity over succession.
在存在映射偏差的情况下，估计等位基因频率、祖先成分比例和基因型似然值	Günther, T.	PDF	N/A	Estimating allele frequencies, ancestry proportions and genotype likelihoods in the presence of mapping bias
细菌基因必要性的实验进化研究	Bao, L.	PDF	N/A	Experimental evolution of gene essentiality in bacteria
使用不同LED光照配方塑造羽衣甘蓝的形态和生理特性	Scandola, S.	PDF	N/A	Shaping Kale Morphology and Physiology Using Different LED Light Recipes
研究交配系统对秀丽隐杆线虫（C. elegans）耐药性进化的影响	Trubenova, B.	PDF	N/A	Investigating the consequences of the mating system for drug resistance evolution in C. elegans
具有不同轴突连接性的皮层投射神经元利用具有不同蛋白质组成的核糖体复合物。	Tran, T. P.	PDF	N/A	Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions
抑制PDE5通过特定激酶迅速诱导海马树突棘的非基因组增加。	Soma, M.	PDF	N/A	Inhibition of PDE5 induces rapid non-genomic increase in hippocampal dendritic spines via specific kinases
亨廷顿蛋白相互作用组揭示了亨廷顿蛋白在调控双链断裂DNA损伤应答（DSB/DDR）、染色质重塑和RNA加工通路中的作用。	Ratovitski, T.	PDF	N/A	Huntingtin interactome reveals huntingtin role in regulation of double strand break DNA damage response (DSB/DDR), chromatin remodeling and RNA processing pathways
基于自动位置和形状优化的可变形大型TMS线圈的个性化电场模拟	Worbs, T.	PDF	N/A	Personalized electric field simulations of deformable large TMS coils based on automatic position and shape optimization
化学诱导型CRISPR/Cas9电路用于超高动态范围的基因扰动	Srinivasan, R.	PDF	N/A	Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation
生物分子凝聚体的细胞功能由其超微结构决定	Scholl, D.	PDF	N/A	Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure
长期来看，芬诺斯坎迪亚（Fennoscandia）地区的石楠荒原和苔原上的维管植物和地衣群落的同质化，与一种具有化感作用的矮灌木的扩张有关。	Maliniemi, T.	PDF	N/A	Long-term homogenization of vascular plant and lichen communities across Fennoscandian heathlands and tundra is connected to the expansion of an allelopathic dwarf shrub
CAZyme3D：碳水化合物活性酶三维结构数据库	Shanmugam, N. R. S.	PDF	N/A	CAZyme3D: a database of 3D structures for carbohydrate-active enzymes
生物分子凝聚体能够诱导局部膜电位	Gurunian, A.	PDF	N/A	Biomolecular Condensates can Induce Local Membrane Potentials
细胞图谱技术揭示了小鼠前列腺的组织结构以及去势抵抗的决定因素	Cho, H.	PDF	N/A	Cellular cartography reveals mouse prostate organization and determinants of castration resistance
RNA结合蛋白HuR在胰腺癌恶病质中损害脂肪组织合成代谢。	Arneson-Wissink, P. C.	PDF	N/A	The RNA-binding protein HuR impairs adipose tissue anabolism in pancreatic cancer cachexia
物体类别训练对猕猴颞下皮层反应的影响与视觉层级内性能优化的更新是一致的。	Sörensen, L. K. A.	PDF	N/A	The effects of object category training on the responses of macaque inferior temporal cortex are consistent with performance-optimizing updates within a visual hierarchy
空间和特征依赖的皮层回路模型中扰动响应的精确线性理论	Chau, H. Y.	PDF	N/A	Exact linear theory of perturbation response in a space- and feature-dependent cortical circuitmodel
在人类唐氏综合症的兴奋性皮层神经元中，神经元网络活动和连接性发生了改变。	Peter, M.	PDF	N/A	Altered neuronal network activity and connectivity in human Down Syndrome excitatory cortical neurons
病理性α-突触核蛋白引发颗粒空泡变性，且不依赖于tau蛋白。	Dues, D.	PDF	N/A	Pathological α-synuclein elicits granulovacuolar degeneration independent of tau
在加利福尼亚旱地生物结皮中发现的新型球囊霉门-苔藓关联	Kelly, K. H.	PDF	N/A	Novel Glomeromycotina-Moss Associations Identified in California Dryland Biocrusts
绝对丰度揭示了蛙粪霉（Basidiobolus）作为跨域桥梁，间接增强了肠道微生物组的稳态。	Ghotbi, M.	PDF	N/A	Absolute abundance unveils Basidiobolus as a cross-domain bridge indirectly bolstering gut microbiome homeostasis
细菌中氨基酸合成与分解代谢电子传递的交叉调控	Mogi, H.	PDF	N/A	Cross-regulation of amino acid synthesis and catabolic electron transfer in bacteria
甲葡胺锑和别嘌呤醇治疗对利什曼病犬粪便微生物组谱的影响	Marti-Carreras, J.	PDF	N/A	Effects of meglumine antimoniate and allopurinol treatment on the fecal microbiome profile in dogs with leishmaniosis
剪接体破坏的直接和间接影响损害了无义介导的mRNA降解（Nonsense-Mediated mRNA Decay, NMD）对基因的调控。	Embree, C. M.	PDF	N/A	Direct and indirect effects of spliceosome disruption compromise gene regulation by Nonsense-Mediated mRNA Decay
miR-126调节神经祖细胞的发育	Bastiaans, J.	PDF	N/A	miR-126 modulates neural progenitor cell development
绿色合成的白兰银纳米颗粒具有杀灭病原体、抑制癌症、展示抗氧化和光催化特性的功能。	De Mel, S.	PDF	N/A	Green Synthesized Magnolia alba Silver Nanoparticles Kill Pathogens, Inhibit Cancer, and Display Antioxidant and Photocatalytic Properties
混合的DAMP/MAMP寡糖能够促进黄瓜的生长并增强其对真菌病原体的防御能力。	Pring, S.	PDF	N/A	Mixed DAMP/MAMP oligosaccharides promote both growth and defense against fungal pathogens of cucumber
角蛋白16在应激皮肤中空间上抑制I型干扰素反应	Cohen, E.	PDF	N/A	Keratin 16 spatially inhibits type I interferon responses in stressed skin
细胞形态学能够准确预测贴壁细胞的核形状。	Lawton, S.	PDF	N/A	Cell Morphology accurately predicts the nuclear shape of adherent cells
通过逆转外胚层区域化实现分化能力的表观遗传恢复	Sutcliffe, M. A.	PDF	N/A	Epigenetic restoration of differentiation competency via reversal of epiblast regionalisation
使用小鼠ICM胚胎模型解码原始内胚层与外胚层之间的相互作用	Tan, B.	PDF	N/A	Decoding primitive endoderm - epiblast interactions using mouse ICM embryoids
在光遗传学视觉恢复中，原生视觉反应与假体视觉反应之间的相互作用	Carpentiero, E.	PDF	N/A	Interaction between native and prosthetic visual responses in optogenetic visual restoration
意志性停止之前会出现短暂的β波振荡。	Doutel Figueira, J. F.	PDF	N/A	Volitional stopping is preceded by a transient beta oscillation
在阿尔茨海默病（AD）中，受阻的AMPK-ULK1级联反应引发了线粒体功能障碍和与AD相关的病理改变，而二甲双胍能够缓解这些症状。	Mary, A.	PDF	N/A	Hampered AMPK-ULK1 cascade in Alzheimer disease (AD) instigates mitochondria dysfunctions and AD-related alterations that are alleviated by metformin
T型Cav3.2钙通道在人类背根神经节神经元中的功能表达及性别二态性	chemin, j.	PDF	N/A	Functional expression and sex dimorphism of the T-type Cav3.2 Calcium Channel in human DRG Neurons
大脑与深度神经网络中语音和语言的收敛表征及其时空动态	Chen, P.	PDF	N/A	Convergent representations and spatiotemporal dynamics of speech and language in brain and deep neural networks
人类中央前回神经元将听与说的语音序列连接起来	Xu, D.	PDF	N/A	Human precentral gyrus neurons link speech sequences from listening to speaking
钙离子动态调节发育节奏，从而在进化过程中产生不同的轴突束长度	Lindhout, F. W.	PDF	N/A	Calcium dynamics tune developmental tempo to generate evolutionarily divergent axon tract lengths
流体智力与认知地图形成的神经测量相关	Tenderra, R. M.	PDF	N/A	Fluid intelligence relates to neural measures of cognitive map formation
糖化胶原蛋白上生物膜的形成调节变形链球菌细菌外泌体的产生及其内容物。	Leiva-Sabadini, C.	PDF	N/A	Biofilm formation on glycated collagen modulates Streptococcus mutans bacterial extracellular vesicle production and cargo
染色体末端通过RAP1介导的DNA-PK抑制实现保护	Eickhoff, P.	PDF	N/A	Chromosome end protection by RAP1-mediated inhibition of DNA-PK
可扩展的功能性肝细胞源自原代细胞，助力肝脏治疗	Mallanna, S. K.	PDF	N/A	Expandable, Functional Hepatocytes Derived from Primary Cells Enable Liver Therapeutics
解析内吞适配蛋白CALM与含有磷脂酰肌醇4,5-二磷酸酯的模型膜结合时的结构分子细节	Santamaria, A.	PDF	N/A	Untangling structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes
来自下波波阿吉组（卡尼阶，三叠纪）的一种新变头螈科（离片椎目）骨床及对离片椎目骨骼分选的评估	Kufner, A.	PDF	N/A	A new metoposaurid (Temnospondyli) bonebed from the lower Popo Agie Formation (Carnian, Triassic) and an assessment of skeletal sorting in temnospondyls
负责玉米（Zea mays）氮吸收的导水根	Jiang, Y.	PDF	N/A	Water-conducting roots responsible for nitrogen uptake in maize (Zea mays)
精英控制者对短暂HIV病毒血症的多维度B细胞反应	Muir, L.	PDF	N/A	Multifaceted B-cell response to transient HIV viraemia in elite controllers
通过循环原位杂交进行空间信息表型分析，识别出系统性硬化症中新型成纤维细胞群体及其致病微环境。	Li, Y.-N.	PDF	N/A	Spatially informed phenotyping by cyclic-in-situ-hybridization identifies novel fibroblast populations and their pathogenic niches in systemic sclerosis
通过对化疗后重新增殖的髓系细胞进行单细胞转录组分析，鉴定出一种具有促肿瘤活性的中性粒细胞样单核细胞亚群。	Ding, Z.-c.	PDF	N/A	Single-cell transcriptome profiling of the myeloid cells repopulating after chemotherapy identifies a neutrophil-like monocyte subset with pro-tumor activities
针对急性髓性白血病的基因编辑“通用”供体CAR T细胞策略	Kadirkamanathan, R.	PDF	N/A	Base edited "universal" donor CAR T cell strategies for acute myeloid leukaemia
1型淋巴细胞和干扰素-γ在丘脑中积聚，并在创伤性脑损伤后限制癫痫易感性。	Mroz, N. M.	PDF	N/A	Type 1 lymphocytes and interferon-γ accumulate in the thalamus and restrict seizure susceptibility after traumatic brain injury
团结一致：从退化的永久冻土中分离并鉴定产胞外多糖的细菌	Waqas, M.	PDF	N/A	Stick together: Isolation and characterization of exopolysaccharide producing bacteria from degraded permafrost soils
PSGL-1通过空间阻碍机制将HIV Env排除在病毒颗粒表面之外，这一过程涉及十聚体重复序列（DR）的结构折叠。	Tiwari, S.	PDF	N/A	PSGL-1 excludes HIV Env from virion surface through spatial hindrance involving structural folding of the decameric repeats (DR)
构建药物敏感型耳念珠菌菌株	Hassan, M.	PDF	N/A	Construction of a drug sensitised Candida auris strain
空间异质性影响弧菌（Vibrio anguillarum）中噬菌体与宿主的共存动态以及噬菌体抗性的发展。	Chen, L.	PDF	N/A	Spatial heterogeneity influences phage-host co-existence dynamics and phage resistance development in Vibrio anguillarum
Tapetum特异性TA29启动子受顺式元件调控，这些顺式元件能够结合正调控因子和负调控因子。	Sharma, P. A.	PDF	N/A	Tapetum specific TA29 promoter is regulated by cis- elements binding to positive and negative regulators
对太平洋牡蛎（Magallana gigas）中染色质免疫共沉淀（ChIP-Seq）方法的基准测试	Dellong, A.	PDF	N/A	Benchmarking of Chromatin Immunoprecipitation (ChIP-Seq) methods in the Pacific oyster Magallana gigas
载脂蛋白-L1 G1变异在载脂蛋白-E敲除小鼠中导致脑积水，但不导致动脉粥样硬化。	Yoshida, T.	PDF	N/A	Apolipoprotein-L1 G1 variant contributes to hydrocephalus but not to atherosclerosis in apolipoprotein-E knock-out mice
在苔藓叶片细胞重编程中的生长素波动与PIN蛋白极化	Tang, H.	PDF	N/A	Auxin fluctuation and PIN polarization in moss leaf cell reprogramming
朝着社区驱动的视觉蛋白质组学迈进：利用大规模冷冻电子断层扫描技术研究莱茵衣藻	Kelley, R.	PDF	N/A	Towards community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii
KDM6组蛋白去甲基化酶抑制剂GSK-J4在多发性骨髓瘤细胞中诱导金属和应激反应	Cribbs, A. P.	PDF	N/A	The KDM6 histone demethylase inhibitor GSK-J4 induces metal and stress responses in multiple myeloma cells
推断马达加斯加指猴（Daubentonia madagascariensis）的精细尺度突变和重组率图谱	Soni, V.	PDF	N/A	Inferring fine-scale mutation and recombination rate maps in aye-ayes (Daubentonia madagascariensis)
在活体人类和小鼠细胞的基因组中，DNA:RNA杂交G-四链体的主要形成	Tan, Z.	PDF	N/A	Dominant Formation of DNA:RNA Hybrid G-Quadruplexes in the Genomes of Living Human and Mouse Cells
以下是这段英文的中文翻译：

分子决定因素导致p115RhoGEF和PDZRhoGEF被激活的Gα13差异性招募的机制

翻译说明： - "Molecular determinants" 翻译为“分子决定因素”，指的是在分子层面上起决定作用的因素。 - "underlying" 翻译为“导致”或“基于”，表示这些因素是某种现象或机制的基础。 - "differential recruitment" 翻译为“差异性招募”，指的是两种蛋白质（p115RhoGEF和PDZRhoGEF）被激活的Gα13以不同方式或程度招募的过程。 - "activated Gα13" 翻译为“激活的Gα13”，指的是处于激活状态的Gα13蛋白。

BioRxiv 2024-12-27 Papers

标题	作者	PDF链接	代码仓库	Title
奥卡姆剃刀如何指导人类决策	Piasini, E.	PDF	N/A	How Occam's razor guides human decision-making
ZapD介导的交联作用促使溶液中短链FtsZ纤维组装成环形结构。	Merino-Salomon, A.	PDF	N/A	Crosslinking by ZapD drives the assembly of short FtsZ filaments into toroidal structures in solution
由胆固醇纳米贴片合成的脂质筏诱导早期T细胞激活	Jung, Y.	PDF	N/A	Synthetic lipid rafts formed by cholesterol nano-patch induce early T cell activation
在多拷贝基因系统中，由遗传漂变驱动的极快速进化所呈现的悖论	Wang, X.	PDF	N/A	The paradox of extremely fast evolution driven by genetic drift in multi-copy gene systems
通过模仿蝴蝶眼睛来模仿蝴蝶翅膀	Dang, A.	PDF	N/A	Mimetic butterfly wings through mimetic butterfly eyes
可扩展的超高通量单细胞染色质和RNA测序揭示了基因调控动态，将巨噬细胞极化与自身免疫疾病联系起来。	Lobato-Moreno, S.	PDF	N/A	Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease
通过外部切趾相位对比显微镜对活体哺乳动物细胞内的结构进行无标记成像	Ohno, H.	PDF	N/A	Label-free imaging of intracellular structures in living mammalian cells via external apodization phase-contrast microscopy
放大的耳间声级差异增强了双侧人工耳蜗使用者的空间释放掩蔽效应。	Richardson, B. N.	PDF	N/A	Magnified interaural level differences enhance spatial release from masking in bilateral cochlear implant users
BulkRNABert：基于批量RNA测序语言模型的癌症预后预测	Gelard, M.	PDF	N/A	BulkRNABert: Cancer prognosis from bulk RNA-seq based language models
循环中的肌肉因子鸢尾素（irisin）水平是否与2型糖尿病相关？一项系统综述与荟萃分析	Aminov, E.	PDF	N/A	Are circulating levels of the myokine irisin linked to type 2 diabetes? A systematic review and meta-analysis
通过从批量转录组到单细胞转录组的半监督迁移学习，识别肿瘤中的耐药性单个细胞。	Huang, K.	PDF	N/A	Identifying drug-resistant individual cells within tumors by semi-supervised transfer learning from bulk to single-cell transcriptome
基因组变化在同属物种对之间存在显著差异。	Francis, W. R.	PDF	N/A	Genomic changes are varied across congeneric species pairs
撤回：ATP依赖性转位酶SMARCAL1、ZRANB3和HLTF在叉逆转过程中对DNA损伤的链依赖性绕过	Adolph, M. B.	PDF	N/A	WITHDRAWN: Strand dependent bypass of DNA lesions during fork reversal by ATP-dependent translocases SMARCAL1, ZRANB3, and HLTF
记录出生后第一个月内小肠转录组的变化	Oliveria, L. F. S.	PDF	N/A	Cataloguing the postnatal small intestinal transcriptome during the first postnatal month
对老鼠而言，什么才是重要的？内部与外部环境对雄性老鼠对雌性吱吱声的声学反应的影响	Brunner, L. R.	PDF	N/A	What matters to a mouse? Effects of internal and external context on male vocal response to female squeaks
Boltz-1：生物分子相互作用建模的民主化	Wohlwend, J.	PDF	N/A	Boltz-1: Democratizing Biomolecular Interaction Modeling
rapgef1b在神经嵴特化和前体节中胚层模式化中的发育功能	Prasad, T.	PDF	N/A	Developmental functions of rapgef1b in neural crest specification and presomitic mesoderm patterning
关键肠道微生物群分类群与环境敏感性和炎症相关生物标志物之间关系的研究	Takasugi, S.	PDF	N/A	Key taxa of the gut microbiome associated with the relationship between environmental sensitivity and inflammation-related biomarkers
神经元功能中的高阶交互：从基因到生物物理模型中的离子电流	Reva, M.	PDF	N/A	Higher-Order Interactions in Neuronal Function: From Genes to Ionic Currents in Biophysical Models
血管内皮生长因子-D在急性肺损伤期间改善肺血管完整性	Yuan, Y.	PDF	N/A	Vascular endothelial growth factor-D improves lung vascular integrity during acute lung injury
在三家长期护理机构中，与养老院获得性肺炎相关的病原体的纵向流行率及共携带情况	Whealy, R. N.	PDF	N/A	Longitudinal prevalence and co-carriage of pathogens associated with nursing home acquired pneumonia in three long-term care facilities
SAR11类群中的生境特异性与少数处于高度选择压力下的基因有关。	Tucker, S. J.	PDF	N/A	Habitat-specificity in SAR11 is associated with a handful of genes under high selection
MethylQUEEN：一种基于甲基化编码的DNA基础模型	Li, M.	PDF	N/A	MethylQUEEN: A Methylation Encoded DNA Foundation Model
基因组-热力学相位同步：麦克斯韦妖式的细胞命运转变调控	Tsuchiya, M.	PDF	N/A	Genomic-Thermodynamic Phase Synchronization: Maxwell's Demon-Like Regulation of Cell Fate Transition
原发效应与传播效应：当与免疫检查点抑制结合时，α粒子与β粒子发射的放射性药物的不同免疫影响	Kerr, C. P.	PDF	N/A	Priming versus propagating: distinct immune effects of an alpha- versus beta-particle emitting radiopharmaceutical when combined with immune checkpoint inhibition
“宏基因组学日”：一个关于使用开放云生物信息学进行环境DNA（eDNA）和微生物组扩增子测序分析的简化研讨会。	Belaouni, H. A.	PDF	N/A	"The Metagenomics Days": a simplified workshop on amplicon sequencing analysis with open cloud bioinformatics for eDNA and Microbiomes
线虫捕捉真菌少孢节丛孢（Arthrobotrys oligospora）渴求COQ7以缓解环境引发的铁过载	Qunfu, W.	PDF	N/A	Nematode-Trapping Fungus Arthrobotrys oligospora is Hungry for COQ7 to Alleviate Environmentally Triggered Iron Overload
高风险儿童肿瘤中从肝母细胞瘤向癌的异步转变	Chen, T.-W.	PDF	N/A	Asynchronous Transitions from Hepatoblastoma to Carcinoma in High-Risk Pediatric Tumors
一种通用策略赋予染料基因荧光，用于活细胞中蛋白质的无洗涤成像	Zhou, X.	PDF	N/A	A General Strategy to Endow Dyes with Genic Fluorescence for Wash-Free Imaging of Proteins in Living Cells
microGalaxy：一个用于微生物数据可重复性和FAIR（可查找、可访问、可互操作、可重用）分析的工具、工作流程和培训的入口平台。	Nasr, E.	PDF	N/A	microGalaxy: A gateway to tools, workflows, and training for reproducible and FAIR analysis of microbial data
从现有遗传变异中进行的克隆扩张支撑了澳大利亚一种新兴植物病原体的进化。	Sparks, A. L.	PDF	N/A	Clonal expansion from standing genetic variation underpins the evolution of an emerging plant pathogen in Australia
前额叶皮层活动预测高架十字迷宫中的焦虑样行为	Smoak, M. A.	PDF	N/A	Prelimbic Cortex Activity Predicts Anxiety-Like Behavior in the Elevated Plus Maze
一种新颖的新生儿筛查方法：利用低成本铁粉进行非靶向蛋白质组分析	Nakajima, D.	PDF	N/A	A novel newborn screening modality: Non-targeted proteome analysis using low-cost iron powders
DIS3L2通过调节Akt信号通路对神经嵴细胞的存活至关重要。	D'Silva, S.	PDF	N/A	DIS3L2 is essential for neural crest survival by modulating Akt signaling
从长春花（Vinca minor）中分离的内生真菌Cosmosporella sp. VM-42是一种生物活性化合物的来源，这些化合物对耐药细菌具有强效的活性。	He, T.	PDF	N/A	The endophytic fungus Cosmosporella sp. VM-42 from Vinca minor is a source of bioactive compounds with potent activity against drug-resistant bacteria
Withaferin A 通过下调 NDRG1 来克服缺氧介导的上皮间质转化（EMT）及肺腺癌和胶质瘤细胞的化疗耐药性。	Mahajan, D.	PDF	N/A	Withaferin A downregulates NDRG1 to overcome hypoxia mediated EMT and chemoresistance in lung adenocarcinoma and glioma cells
玉米中的TIR-only蛋白ZmTIR1和ZmTIR2，而非ZmTIR3，可能通过形成凝聚体来赋予自激活的超敏反应。	Kang, Z.-X.	PDF	N/A	Maize TIR-only Proteins ZmTIR1 and ZmTIR2, but not ZmTIR3 Confer Auto-active Hypersensitive Response Likely by Forming Condensation
《用于CRISPR应用的非冗余短聚合酶III启动子汇编》	Deguchi, M.	PDF	N/A	A compendium of nonredundant short Polymerase III promoters for CRISPR applications
重塑表观基因组景观以促进面包小麦的物种形成	Zhang, Z.	PDF	N/A	Reshaping epigenomic landscapes in facilitating the speciation of bread wheat
年龄与认知功能对噪声环境下语音神经追踪的影响	An, H.	PDF	N/A	Effects of Age and Cognitive Functions on the Neural Tracking of Speech in Noise
感知基于变形的运动方向	Kawabe, T.	PDF	N/A	Perceiving direction of deformation-based motion
Enolase-1 在急性炎症期间对中性粒细胞的募集至关重要。	Lu, H.-Y.	PDF	N/A	Enolase-1 is essential for neutrophil recruitment during acute inflammation
CRISPR-Cas系统监管多种抗噬菌体防御机制。	Li, M.	PDF	N/A	CRISPR-Cas supervises diverse anti-phage defense systems
用于微槽基底上细胞核聚类的变分自编码器模型：疾病诊断的潜力	Roellinger, B.	PDF	N/A	A Variational Autoencoder Model for Clustering of Cell Nuclei on Microgroove Substrates: Potential for Disease Diagnosis
《番荔枝高质量基因组组装为这一新兴水果作物提供了功能性见解》

该研究通过对番荔枝（Annona squamosa，又称释迦果）进行高质量基因组测序和组装，深入解析了这一新兴热带水果作物的基因组特征和功能基因。研究不仅揭示了番荔枝的基因组结构和进化历程，还鉴定出与果实品质、风味和抗病性相关的重要基因。这些发现为番荔枝的遗传改良和育种提供了宝贵的分子基础，有助于推动这一具有高经济价值作物的可持续发展。 | Bisht, M. S. | PDF | N/A | A High-quality Genome Assembly of Annona squamosa (Custard Apple) Provides Functional Insights into an Emerging Fruit Crop | | 开源细胞培养自动化系统，集成了细胞计数功能，用于微孔板培养的传代操作。 | Courville, G. | PDF | N/A | Open-source cell culture automation system with integrated cell counting for passaging microplate cultures | | 探索自然盟友：葡萄园中葡萄果蛾幼虫寄生蜂的调查与鉴定，以实现可持续管理 | Gomez-Llano, J. H. | PDF | N/A | Exploring natural allies: Survey and identification of larval parasitoids for sustainable grape berry moth management in vineyards | | 一种利用多聚腺苷酸聚合酶和寡聚脱氧胸苷酸依赖性的方法，用于纯化工程化环状RNA，以增强其在真核细胞中的蛋白质表达。 | Wei, L. | PDF | N/A | A poly(A) polymerase and oligo(dT)-dependent method for the purification of engineering circular RNAs that enhances protein expression in eukaryotic cells | | ThermoPlex：一种基于DNA热力学的靶向特异性多重PCR引物自动设计工具 | Agmata, A. | PDF | N/A | ThermoPlex: An Automated Design Tool for Target-specific Multiplex PCR Primers based on DNA Thermodynamics | | 2013年至2022年巴西米纳斯吉拉斯州牛只运输网络脆弱性分析 | Costa, A. C. T. R. B. | PDF | N/A | Network vulnerability of cattle movement in Minas Gerais, Brazil, from 2013 to 2022 | | 由钠动力驱动的平肠球菌V-ATP酶的ATP合成 | Otomo, A. | PDF | N/A | ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force | | 成年小鼠视觉皮层中移植的中间神经元在新的眼优势可塑性时期的整合 | Rakela, B. | PDF | N/A | Integration of Transplanted Interneurons Over a New Period of Ocular Dominance Plasticity in Adult Mouse Visual Cortex | | 将酪氨酸羟化酶神经元中的Latrophilin-3条件性敲除（Lphn3-Th-Cre）与Lphn3全局敲除大鼠进行比较：Lphn3在酪氨酸羟化酶神经元中的作用对这一ADHD易感基因的认知和行为效应的影响。 | Regan, S. L. | PDF | N/A | Latrophilin-3 conditional knockout in tyrosine hydroxylase neurons (Lphn3-Th-Cre) compared with Lphn3 global KO rats: Role of Lphn3 in tyrosine hydroxylase neurons on cognitive and behavioral effects of this ADHD susceptibility gene | | 小白蛋白阳性中间神经元的形态计量学识别：一种数据驱动的方法 | Panday, M. | PDF | N/A | Morphometric Identification of Parvalbumin-Positive Interneurons: A Data-Driven Approach | | 哺乳动物杏仁核中未成熟神经元的系统发育变异：在灵长类扩展核中向新皮层投射的高发生率 | Ghibaudi, M. | PDF | N/A | Phylogenetic variation of immature neurons in mammalian amygdala: high prevalence in primate expanded nuclei projecting to neocortex | | 海马体中距离与位置的独立编码机制 | Nordlund, M. | PDF | N/A | An Independent Coding Scheme for Distance versus Position in the Hippocampus | | 用于阿尔茨海默病诊断和分期的FDG PET亚区域生物标志物：一个可解释且可理解的模型 | Rasi, R. | PDF | N/A | Subregional Biomarkers in FDG PET for Alzheimer's Diagnosis and Staging: An Interpretable and Explainable model | | 截短的TrkB：痛觉感受器中的主要TrkB亚型 | Ruparel, J. | PDF | N/A | Truncated TrkB: The predominant TrkB Isoform in Nociceptors | | 最佳耳蜗位置在电听觉中传递双耳时间线索 | Borjigin, A. | PDF | N/A | Best Cochlear Locations for Delivering Interaural Timing Cues in Electric Hearing | | 小学学生口腔微生物群与近距离接触之间的关联 | Dall'Amico, L. | PDF | N/A | Association Between Oral Microbiota and Close-Range Proximity in a Primary School | | 苜蓿根中的酚类化合物受到根瘤农杆菌（Agrobacterium fabrum）通过其物种特异性基因区域的影响。 | Padilla, R. | PDF | N/A | Phenolic compounds in Medicago truncatula roots are under the influence of Agrobacterium fabrum through its species specific-genes regions | | 营养诱导增强了植物对拮抗性昆虫食果动物的抵抗力。 | Jacobsen, D. J. | PDF | N/A | Vegetative induction increases plant resistance to antagonistic insect frugivores | | AtKC1通过其氨基端抑制结构域抑制AtAKT1的激活。 | Zheng, Z. | PDF | N/A | AtKC1 inhibits AtAKT1 activation via its amino-terminal inhibitory domain | | 用于大分子治疗剂胞质递送的条件性融合脂质纳米载体 | Zhong, Q. | PDF | N/A | Conditional fusogenic lipid nanocarriers for cytosolic delivery of macromolecular therapeutics | | 通过超声波信号可以检测组织中的生化状态。 | Ito, K. | PDF | N/A | Biochemical state in tissue can be detected through ultrasound signal | | 前脚掌着地与后脚掌着地对下肢损伤生物力学风险因素及急停跳跃任务表现的影响 | Huang, T. | PDF | N/A | Effects of Forefoot versus Rearfoot Landing on Biomechanical Risk Factors for Lower Limb Injuries and Performance During Stop-Jump Tasks | | 基于序列的协同进化预测物种特异性相互作用组 | Fernandez-Martin, M. | PDF | N/A | Sequence-based coevolutionary prediction of species-specific interactomes | | 在向新生态系统过渡的过程中，水平基因转移率会下降。 | Mishra, S. | PDF | N/A | Horizontal gene transfer rates decrease during transitions to new ecosystems | | 水平基因转移推断：基因存在-缺失优于基因树 | Mishra, S. | PDF | N/A | Horizontal Gene Transfer Inference: Gene presence-absence outperforms gene trees | | 基于3D结构的生成性小分子药物设计：我们实现了吗？ | Yang, B. | PDF | N/A | 3D Structure-based Generative Small Molecule Drug Design: Are We There Yet? | | 在膨压作用下，边界流动诱导的膜管化现象 | Xue, H. | PDF | N/A | Boundary flow induced membrane tubulation under turgor pressures | | 通过膜屈曲法测定高斯曲率模量和自发曲率 | Wang, M. | PDF | N/A | Determination of Gaussian curvature modulus and spontaneous curvature via membrane buckling | | 基因组改变与免疫微环境特征的组合与多种癌症类型患者的生存率相关。 | Bayati, M. | PDF | N/A | Combinations of genomic alterations and immune microenvironmental features associate with patient survival in multiple cancer types | | 向光蛋白的定位与相互作用调控莱茵衣藻的光生理过程 | Sharma, S. | PDF | N/A | Phototropin localization and interactions regulate photophysiological processes in Chlamydomonas reinhardtii | | 栽培小麦和野生小麦种子携带微生物群的生态组装动态 | Ozkurt, E. | PDF | N/A | Ecological assembly dynamics of the seed-borne microbiome in cultivated and wild wheat | | 利用全长16S rRNA测序技术评估饲料配方和年龄对实验室及大规模饲养的地中海果蝇目标肠道微生物群定殖的影响 | Mason, C. J. | PDF | N/A | Utilizing full-length 16S rRNA sequencing to assess the impact of diet formulation and age on targeted gut microbiome colonization in laboratory and mass-reared Mediterranean fruit flies | | 在Citrin缺乏症中，甘油-3-磷酸激活ChREBP、FGF21转录以及脂肪生成。 | Tiwari, V. | PDF | N/A | Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in Citrin Deficiency | | 物种丰富但数据匮乏：利用分布建模技术绘制南亚水域鲸类动物分布图 | Samad, I. | PDF | N/A | Species rich but data poor: leveraging distribution modelling techniques to map cetacean occurrence in South Asian waters | | 病毒种群中的遗传变化：宿主物种组成的突然变化与逐渐变化如何影响病毒种群遗传变异性的稳定性和动态 | Silva, J. M. F. | PDF | N/A | Genetic shifts in viral populations: how sudden vs gradual changes in host species composition affect the stability and dynamics of genetic variability in viral populations | | 了解野生蜱种群中微生物群变异的机制 | Noguerales, V. | PDF | N/A | Understanding the mechanisms underlying microbiota variation in wild tick populations | | GPR4拮抗剂NE-52-QQ57在感染SARS-CoV-2的K18-hACE2转基因小鼠中提高了生存率，减轻了过度炎症反应，并降低了病毒载量。 | Wu, X.-J. | PDF | N/A | The GPR4 antagonist NE-52-QQ57 increases survival, mitigates the hyperinflammatory response and reduces viral load in SARS-CoV-2-infected K18-hACE2 transgenic mice | | 1型树突状细胞控制癌症中三级淋巴结构的形成、维持和功能。 | Mattiuz, R. | PDF | N/A | Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoidstructures in cancer | | SARS-CoV-2变种LF.7.2.1、NP.1和LP.8.1的病毒学与抗原特性 | Liu, J. | PDF | N/A | Virological and antigenic characteristics of SARS-CoV-2 variants LF.7.2.1, NP.1, and LP.8.1 | | 小分子β-抑制蛋白调节剂 | Kahsai, A. W. | PDF | N/A | Small Molecule Modulators of Beta-arrestins | | 仿生多孔分级支架力学行为中实际应力与原位形态变化的关系 | Marchiori, G. | PDF | N/A | RELATIONSHIP BETWEEN ACTUAL STRESS AND IN SITU MORPHOLOGICAL CHANGES IN THE MECHANICAL BEHAVIOR OF BIOMIMETIC POROUS HIERARCHICAL SCAFFOLDS | | 靶向内皮细胞ERG以减轻视网膜病变中的血管退化和神经元缺血 | Ma, E. | PDF | N/A | Targeting endothelial ERG to mitigate vascular regression and neuronal ischemia in retinopathies | | MUTE驱动不对称分裂以在景天科多肉植物中形成气孔副卫细胞 | Cheng, X. | PDF | N/A | MUTE drives asymmetric divisions to form stomatal subsidiary cells in Crassulaceae succulents | | 基因标记的前髓鞘形成少突胶质细胞：连接少突胶质细胞生成与神经元活动的桥梁 | Bhambri, A. | PDF | N/A | Genetically Labeled Premyelinating Oligodendrocytes: Bridging Oligodendrogenesis and Neuronal Activity | | 《单细胞分辨率下的秀丽隐杆线虫神经系统性别特异性神经元调控蓝图》 | Haque, R. | PDF | N/A | A Blueprint of Sex-Specific Neuronal Regulation in the C. elegans Nervous System at Single-Cell Resolution | | 通过全视野视网膜电图揭示闪烁光诱导的小鼠视网膜刺激效应 | RAI, M. | PDF | N/A | Effect of flicker-induced retinal stimulation of mice revealed by full-field electroretinography | | 长期来看，产前压力对小鼠背侧纹状体及相关行为的细胞类型特异性影响 | Evans, M. M. | PDF | N/A | Long-term, cell type-specific effects of prenatal stress on dorsal striatum and relevant behaviors in mice | | SLC35A2功能丧失变异影响糖组学特征、神经元命运及网络动态。 | Dulcie, L. | PDF | N/A | SLC35A2 loss of function variants affect glycomic signatures, neuronal fate, and network dynamics | | TMEM63A，与低髓鞘化白质营养不良相关，是一种在进化上保守的髓鞘形成调节因子。 | Halford, J. | PDF | N/A | TMEM63A, associated with hypomyelinating leukodystrophies, is an evolutionarily conserved regulator of myelination | | 一类新型青霉素结合蛋白抑制剂用于应对耐药性淋病奈瑟菌 | Uehara, T. | PDF | N/A | A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae | | 在果蝇（Drosophila melanogaster）中，脂肪组织中性别二态性的ATF4表达赋予了雌性应激耐受性。 | Grmai, L. | PDF | N/A | Sexually dimorphic ATF4 expression in the fat confers female stress tolerance in Drosophila melanogaster |

BioRxiv 2024-12-26 Papers

标题	作者	PDF链接	代码仓库	Title
通过互信息识别局部神经可塑性	Scheler, G.	PDF	N/A	Localist Neural Plasticity Identified By Mutual Information
使用单序列输入对AlphaFold-Multimer结构进行优化	Oda, T.	PDF	N/A	Refinement of AlphaFold-Multimer structures with single sequence input
CLEM-Reg：一种基于点云的自动化配准算法，用于关联光学显微镜和体电子显微镜	Krentzel, D.	PDF	N/A	CLEM-Reg: An automated point cloud based registration algorithm for correlative light and volume electron microscopy
可预测的模态转换与无模态表征促进了跨模态统计学习	Perez-Bellido, A.	PDF	N/A	Predictable Modality Transitions and Amodal Representations Enable Crossmodal Statistical Learning
大脑芳香化酶及其与雄性小鼠亲代经验和行为的关系	Duarte-Guterman, P.	PDF	N/A	Brain aromatase and its relationship with parental experience and behavior in male mice
一项新颖的系统基因组学分析流程揭示了葫芦目植物网状进化的复杂模式。	Ortiz, E. M.	PDF	N/A	A novel phylogenomics pipeline reveals complex pattern of reticulate evolution in Cucurbitales
电子自旋、手性及电荷动力学在促进新生核酸-肽复合物持久性中的作用	Vyas, P.	PDF	N/A	The Role of Electron Spin, Chirality, and Charge Dynamics in Promoting thePersistence of Nascent Nucleic Acid-Peptide Complexes
小RNA通过调节Rho利用位点的可及性，正向和负向地控制转录延伸。	Farley, K. R.	PDF	N/A	Small RNAs positively and negatively control transcription elongation through modulation of Rho utilization site accessibility
广义哈德恩（GH）模型用于追踪种群规模的变化，并解决遗传漂变中的悖论。	Ruan, Y.	PDF	N/A	The Generalized Haldane (GH) model tracking population size changes and resolving paradoxes of genetic drift
传统农业系统的复兴——一项关于玉米与豆类间作的多学科田间调查揭示了豆类受到意外竞争效应的影响。	Vazeux-Blumental, N.	PDF	N/A	Revival of traditional agricultural systems - A multidisciplinary on-farm survey of maize-bean intercropping reveals unexpected competition effects on bean.
组胺对纹状体多巴胺调节的性别二态性	Van Zandt, M.	PDF	N/A	Sexual dimorphism in histamine regulation of striatal dopamine
跨不同交配系统作物的半合子基因的基因组和表观基因组动态	Peng, Y.	PDF	N/A	The genomic and epigenomic dynamics of hemizygous genes across crops with contrasting mating systems
ECloudGen：利用电子云作为潜在变量扩展基于结构的分子设计	Zhang, O.	PDF	N/A	ECloudGen: Leveraging Electron Clouds as a Latent Variable to Scale Up Structure-based Molecular Design
一种稳定的MERS-CoV刺突蛋白铁蛋白纳米颗粒疫苗能够引发强大且具有保护性的中和抗体反应。	Powell, A. E.	PDF	N/A	A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses
生物物理模拟实现多尺度分割与图谱映射，助力神经系统自上而下的空间组学研究。	Mohammed Ali, L. K.	PDF	N/A	Biophysical Simulation Enables Multi-Scale Segmentation and Atlas Mapping for Top-Down Spatial Omics of the Nervous System
PTEN的neddylation修饰加剧了乳腺癌对CDK4/6抑制剂的耐药性。	Liu, F.	PDF	N/A	PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
在Slc29a3/Unc5b基因座中，由TAD边界破坏引起的转录变化的方向和模式取决于组织特异性的表观遗传背景。	Salnikov, P. A.	PDF	N/A	Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context
多元醇糖渗透调节剂——山梨醇能够纠正黏连蛋白（cohesin）突变体中的染色体黏连和翻译缺陷。	BOSE, T.	PDF	N/A	Polyol sugar osmolyte - sorbitol corrects chromosome cohesion and translational defects in cohesin muta
多元醇糖渗透调节剂——山梨醇，能够纠正黏连蛋白突变中的染色体黏连和翻译缺陷。	BOSE, T.	PDF	N/A	Polyol sugar osmolyte - sorbitol corrects chromosome cohesion and translational defects in cohesin muta
这段文字翻译成中文是：“RanBP2、SUMO1-RanGAP1、E2 Ubc9、Crm1和Ran GTPase之间核孔蛋白输出复合物的结构基础”。
这段描述涉及多个蛋白质和分子复合物的相互作用，主要与核孔蛋白的运输机制相关。	Baytshtok, V.	PDF	N/A	Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase
贝克尔型肌营养不良症小鼠表现出骨骼肌中IIa型纤维的特定部位退化，并伴有毛细血管变化。	Miyazaki, D.	PDF	N/A	Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle
一项关于离线5Hz-rTUS诱导皮质脊髓兴奋性的双盲重复实验尝试	Fong, P.-Y.	PDF	N/A	A Double-Blind Replication Attempt of Offline 5Hz-rTUS-Induced Corticospinal Excitability
欧洲河七鳃鳗（Lampetra fluviatilis）与溪七鳃鳗（Lampetra planeri）全基因组组装的比较	Torresen, O. K.	PDF	N/A	Comparison of whole-genome assemblies of European river lamprey (Lampetra fluviatilis) and brook lamprey (Lampetra planeri)
以下是这段英文的中文翻译：

东方马脑炎病毒在易感宿主细胞内复制的详细动力学模型

翻译说明： - "Eastern equine encephalitis virus" 翻译为 "东方马脑炎病毒"，这是一种由蚊子传播的病毒，主要影响马匹和人类。 - "replication" 翻译为 "复制"，指的是病毒在宿主细胞内增殖的过程。 - "susceptible host cell" 翻译为 "易感宿主细胞"，指的是容易被病毒感染的细胞。 - "detailed kinetic model" 翻译为 "详细动力学模型"，指的是对病毒复制过程中各步骤的定量描述和分析。

希望这个翻译对你有帮助！如果有其他问题，欢迎随时提问。 | Larkin, C. I. | PDF | N/A | A detailed kinetic model of Eastern equine encephalitis virus replication in a susceptible host cell | | 预训练的蛋白质语言模型用于密码子优化 | Pathak, S. | PDF | N/A | Pre-trained protein language model for codon optimization | | I2SIM：通过图像干扰与空间频谱优化提升高保真各向同性超分辨率 | He, E. | PDF | N/A | I2SIM: Boosting High-Fidelity Isotropic Super-Resolution with Image Interference and Spatial-Spectrum Optimization | | Verkko2：通过整合邻近连接数据与长读长De Bruijn图，实现高效的端粒到端粒基因组组装、定相和支架构建。 | Phillippy, A. M. | PDF | N/A | Verkko2: Integrating proximity ligation data with long-read De Bruijn graphs for efficient telomere-to-telomere genome assembly, phasing, and scaffolding | | SenSet，一种新型的人类肺衰老细胞基因特征，能够识别细胞特异性的衰老机制。 | Hasanaj, E. | PDF | N/A | SenSet, a novel human lung senescence cell gene signature, identifies cell-specific senescence mechanisms | | 对于小立碗藓（Physcomitrium patens）原丝体发育至关重要的过程，需要由功能冗余的PpROP GTPases提供的不同水平的总活性。 | Le Bail, A. | PDF | N/A | Processes essential for Physcomitrium patens protonemal development require distinct levels of total activity provided by functionally redundant PpROP GTPases | | 不同基因型的微囊藻对青鳉鱼造成的独特生态毒理学损害 | MARIE, B. | PDF | N/A | Distinct ecotoxicological impairs induced by different Microcystis genotypes to Medaka fish | | 基于RiboTag的RNA测序揭示了自身免疫性脑脊髓炎中少突胶质细胞谱系特异性炎症 | Wang, Y. | PDF | N/A | RiboTag-based RNA-Seq uncovers oligodendroglial lineage-specific inflammation in autoimmune encephalomyelitis | | 遗传方差的演变及其对复杂互惠网络中协同进化反应的影响 | Baruah, G. | PDF | N/A | Evolution of genetic variance and its consequences oneco-evolutionary response in complex mutualistic networks | | 长期评估猴子大脑中DREADD表达及效力的研究 | Nagai, Y. | PDF | N/A | Longitudinal assessment of DREADD expression and efficacy in the monkey brain | | 周质丝氨酸蛋白酶Prc负责大肠杆菌中淀粉样亚基CsgA的降解和蛋白质稳态。 | Sugimoto, S. | PDF | N/A | Periplasmic serine protease Prc is responsible for amyloid subunit CsgA degradation and proteostasis in Escherichia coli | | 周质丝氨酸蛋白酶Prc在大肠杆菌中负责淀粉样蛋白亚基CsgA的降解和蛋白质稳态。 | Sugimoto, S. | PDF | N/A | Periplasmic serine protease Prc is responsible for amyloid subunit CsgA degradation and proteostasis in Escherichia coli | | XhetRel：一种用于测序数据中X染色体杂合度及相关性分析的流程 | Salman, B. | PDF | N/A | XhetRel: A Pipeline for X Heterozygosity and Relatedness Analysis in Sequencing Data | | 脂肪酸辅酶A还原酶FAR1对于睾丸半乳糖脂的合成、精子生成以及男性生育能力至关重要。 | Tamazawa, A. | PDF | N/A | Fatty acyl-CoA reductase FAR1 is essential for testicular seminolipid synthesis, spermatogenesis, and male fertility | | 白色念珠菌通过激活EGFR诱导缺氧反应，促进结直肠癌的进展 | Wang, W. | PDF | N/A | Candida albicans induce hypoxia response via activating EGFR to promote colorectal cancer progression | | 扩大药物组合表面预测 | Huusari, R. | PDF | N/A | Scaling up drug combination surface prediction | | 一个集成且可扩展的啮齿动物笼具系统，能够实现基于计算机视觉的持续行为分析，并推动人工智能增强的数字生物标志物开发。 | Robertson, T. L. | PDF | N/A | An integrated and scalable rodent cage system enabling continuous computer vision-based behavioral analysis and AI-enhanced digital biomarker development | | 基于结构的病理RET突变悖论效应机制原理 | Fassler Bakhman, A. | PDF | N/A | Structure-based mechanistic principles for the paradoxical effects of pathological RET mutations | | BSReadSim：一款多功能且高效的模拟器，用于生成真实的重亚硫酸盐测序读段 | Guo, W. | PDF | N/A | BSReadSim: a versatile and efficient simulator to generate realistic bisulfite sequencing reads | | 通过混叠技术提高斜平面显微镜的采集速度 | McFadden, C. | PDF | N/A | Increasing the acquisition speed in oblique plane microscopy via Aliasing | | 在头部固定的啮齿动物中，行为状态和身体运动对海马尖波涟漪的调节 | Rios, A. | PDF | N/A | Modulation of hippocampal sharp-wave ripples by behavioral states and body movements in head-fixed rodents | | 分析环境中的伯克霍尔德菌属（Burkholderia sensu lato）分离株在斑马鱼胚胎模型中引发感染的潜力 | Gigan, J. | PDF | N/A | Analysis of the potential of environmental Burkholderia sensu lato isolates to cause infection in a zebrafish embryo model | | 病原体通过高空风传播的蚊子扩散。 | Bamou, R. | PDF | N/A | Pathogens spread by high-altitude windborne mosquitoes | | 异位基因转换导致数量性状变异 | Pfalz, M. | PDF | N/A | Ectopic gene conversion causing quantitative trait variation | | 慢性感染奥赛病毒（Orsay virus）的秀丽隐杆线虫（Caenorhabditis elegans）会诱导出年龄依赖的免疫反应和超感染排斥现象。 | Castiglioni, V. G. | PDF | N/A | Chronic infection of Caenorhabditis elegans by Orsay virus induces age-dependent immunity and superinfection exclusion | | 将α-石英薄膜的晶圆级集成应用于超高频率压电生物NEMS，用于虫媒病毒检测 | Rathar, R. | PDF | N/A | Wafer-scale integration of alpha-quartz thin films towards super high frequency piezoelectric bioNEMS for arbovirus detection | | 基于结构设计的人类白细胞介素-6小分子抑制剂 | Joshi, A. | PDF | N/A | Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6 | | PHALCON：基于大规模单细胞面板测序数据集的系统发育感知变异检测 | Priya, P. | PDF | N/A | PHALCON: phylogeny-aware variant calling from large-scale single-cell panel sequencing datasets | | 甘蔗携带了相对较大的CAMTA转录因子家族，这些因子对干旱胁迫具有活性。 | Costa da Silva, V. L. | PDF | N/A | Sugarcane carries relatively larger family of CAMTA transcription factors, active against drought stress | | 蛋白质变构中的波动驱动协同作用、冗余性、信噪比与纠错机制 | Erman, B. | PDF | N/A | Fluctuation-Driven Synergy, Redundancy, Signal to Noise Ratio and Error Correction in Protein Allostery | | EVOLVE：一个基于多序列数据进行进化阶段分析和新变种探索的网页平台 | Sangeet, S. | PDF | N/A | EVOLVE: A Web Platform for Evolutionary Phase Analysis and New Variant Exploration from Multi-Sequence Data | | 真实与模拟微重力条件下红细胞的比较分析 | Hinge, S. B. | PDF | N/A | Comparative analysis of red blood cell under real and simulated microgravity conditions | | McsB通过外围精氨酸磷酸化调控CtsR的热感应功能。 | Cai, H. | PDF | N/A | McsB regulates CtsR thermosensing through periphery arginine phosphorylation | | 肿瘤来源的LAMA5对于肿瘤的起始至关重要，并且控制着管腔型乳腺癌的进展和表型。 | Ritchie, A. | PDF | N/A | Tumour-derived LAMA5 is critical for tumour initiation and controls progression and phenotype in luminal breast cancer | | 动物授粉物种中花色素频率的跨大陆模式 | Narbona, E. | PDF | N/A | Transcontinental patterns in floral pigment frequencies among animal-pollinated species | | 硝酸盐状态通过拟南芥茎腺苷酸异戊烯基转移酶3调节茎生长及系统性转录反应。 | Monden, K. | PDF | N/A | Shoot nitrate status regulates Arabidopsis shoot growth and systemic transcriptional responses via shoot adenylate isopentenyltransferase 3 | | 在静止的啮齿动物中，包括摄食行为在内的身体活动期间，海马体的尖波涟漪会减少。 | Sakairi, T. | PDF | N/A | Hippocampal sharp-wave ripples decrease during physical actions including consummatory behavior in immobile rodents | | 卵清蛋白负载的介孔二氧化硅纳米颗粒用于过敏原特异性免疫治疗 | Perez-Moreno, A. M. | PDF | N/A | Ovalbumin-loaded mesoporous silica nanoparticles for allergen specific immunotherapy | | 六种类型腺病毒中和抗体的血清流行率与交叉反应性研究 | Zubkova, O. V. | PDF | N/A | Seroprevalence and cross-reactivity of neutralizing antibodies to six types of adenoviruses | | 生成一种表达间日疟原虫环子孢子蛋白的转基因猕猴疟原虫，用于在非人灵长类动物中测试红细胞前期疟疾疫苗。 | Aleshnick, M. | PDF | N/A | Generation of a transgenic P. cynomolgi parasite expressing P. vivax circumsporozoite protein for testing pre-erythrocytic malaria vaccines in non-human primates | | FAM162A 对线粒体的结构、动态和生物能量学至关重要，推动细胞保护和延长寿命 | Matamoros, A. | PDF | N/A | FAM162A is Crucial for Mitochondrial Structure, Dynamics, and Bioenergetics, Driving Cellular Protection and Longevity | | MethylQUEEN：一种基于甲基化编码的DNA基础模型 | Li, M. | PDF | N/A | MethylQUEEN: A Methylation Encoded DNA Foundation Model | | 基因组-热力学相位同步：麦克斯韦妖般的细胞命运转变调控 | Tsuchiya, M. | PDF | N/A | Genomic-Thermodynamic Phase Synchronization: Maxwell's Demon-Like Regulation of Cell Fate Transition | | 长期适应缺氧环境的研究为我们揭示了铜绿假单胞菌（Pseudomonas aeruginosa）转变为慢性肺部感染的内在机制提供了重要线索。 | Drabinska, J. | PDF | N/A | Long-term adaptation to hypoxia provides insight into mechanisms facilitating the switch of Pseudomonas aeruginosa to chronic lung infections | | 生物学考试很少使用视觉模型来激发高阶认知技能。 | Uminski, C. | PDF | N/A | Biology exams rarely use visual models to engage higher-order cognitive skills | | 通过干扰右背外侧前额叶皮层来阻碍记忆抑制 | Stramaccia, D. F. | PDF | N/A | Hindering memory suppression by perturbing the right dorsolateral prefrontal cortex | | 背外侧前额叶皮层经颅磁刺激（TMS）引发膝下前扣带皮层的反应：来自人类颅内脑电图（EEG）的证据 | Trapp, N. T. | PDF | N/A | Dorsolateral prefrontal cortex TMS evokes responses in the subgenual anterior cingulate cortex: Evidence from human intracranial EEG | | 运动序列学习涉及对下一个动作的更好预测以及运动轨迹的优化。 | Kashefi, M. | PDF | N/A | Motor sequence learning involves better prediction of the next action andoptimization of movement trajectories | | 精神分裂症中的神经发育偏差：基于多模态连接组脑年龄的证据 | Fan, Y.-S. | PDF | N/A | Neurodevelopmental deviations in schizophrenia: Evidences from multimodal connectome-based brain ages | | 生物和人工神经网络中表示的普遍性 | Hosseini, E. A. | PDF | N/A | Universality of representation in biological and artificial neural networks | | 大多数自噬性细胞死亡研究缺乏因果关系的证据 | Ghaseminejad, Y. | PDF | N/A | Most Autophagic Cell Death Studies Lack Evidence of Causality | | 印度脊椎动物传粉的经济价值 | Kallivalappil, R. | PDF | N/A | The economic value of vertebrate pollination in India | | 抗生素对东非共同体中铜绿假单胞菌基因组表达的影响：系统综述 | Vandu, C. D. | PDF | N/A | Impact of Antibiotics on the Genomic Expression of Pseudomonas aeruginosa in the East African Community: A Systematic Review | | 1001G+项目：一个精选的拟南芥长读长基因组组装集合，旨在推动植物研究进展 | Alonso-Blanco, C. C. | PDF | N/A | The 1001G+ project: A curated collection of Arabidopsis thaliana long-read genome assemblies to advance plant research | | 肥胖中血管生成信号的综合分析：毛细血管特征与VEGF结合动力学 | Lee, Y. | PDF | N/A | Integrative analysis of angiogenic signaling in obesity: capillary features and VEGF binding kinetics | | 评估某领域因欺诈性研究而面临风险的框架 | Ni, C. | PDF | N/A | Framework for assessing the risk to a field from fraudulent research | | 果蝇距离估计的视觉神经回路 | Shomar, J. | PDF | N/A | Visual circuitry for distance estimation in Drosophila | | 聚类方法在蛋白质功能注释中的适用性如何？ | Busi, R. | PDF | N/A | How suitable are clustering methods for functional annotation of proteins? | | 一种新的纳米差示扫描荧光法（nanoDSF）用于抗微管蛋白化合物筛选，揭示了已批准药物中的新型微管靶向剂（MTAs）。 | Baksheeva, V. E. | PDF | N/A | A new nanoDSF approach to anti-tubulin compounds screening revealed novel MTAs among approved drugs. | | KAT8通过增强HPV相关宫颈癌中E7蛋白的功能，促进癌细胞的增殖。 | Xu, A. | PDF | N/A | KAT8 facilitates the proliferation of cancer cells through enhancing E7 function in HPV-associated cervical cancer | | 循环FGF21与生理及生活方式特征之间关系的探索性研究 | Peterson, M. | PDF | N/A | Relationship Between Circulating FGF21 and Physiological and Lifestyle Characteristics, an Exploratory Study | | 小鼠和人类皮质突触的超微结构膜动力学 | Eddings, C. R. | PDF | N/A | Ultrastructural membrane dynamics of mouse and human cortical synapses | | 攻击性经历与观察共同促进行为和神经层面的变化 | Falkner, A. L. | PDF | N/A | Aggression experience and observation promote shared behavioral and neural changes | | 基于人类脑脊液的因子对神经元动力学的促认知重塑 | Dos Santos, M. | PDF | N/A | Pro-cognitive reshaping of neuronal dynamics by a human CSF-based factor | | 帕金森病小鼠模型运动活动的亚秒级表征 | Berezhnoi, D. | PDF | N/A | Sub-second characterization of locomotor activities of mouse models of Parkinsonism | | 组蛋白H3.3在髓系细胞发育过程中确保细胞增殖和基因组稳定性 | Chauhan, S. | PDF | N/A | Histone H3.3 ensures cell proliferation and genomic stability during myeloid cell development | | 视网膜类器官反映了在体内观察到的CRISPR/Cas9基因编辑效率。 | Pulman, J. | PDF | N/A | Retinal organoids mirror CRISPR/Cas9 gene editing efficiency observed in vivo | | 从冰芯到恐龙：物理藏品管理者的研究数据管理认知与行为 | Bishop, B. W. | PDF | N/A | From Ice Cores to Dinosaurs: Physical Collections Managers' Research Data Curation Perceptions and Behaviors | | TLS_Finder：一种利用免疫细胞空间坐标识别三级淋巴结构的算法 | Koksoy, A. A. | PDF | N/A | TLS_Finder: An algorithm for Identifying Tertiary Lymphoid Structures Using Immune Cell Spatial Coordinates | | TLS_Finder：一种利用免疫细胞空间坐标识别三级淋巴结构的算法 | Koksoy, A. A. | PDF | N/A | TLS_Finder: An algorithm for Identifying Tertiary Lymphoid Structures Using Immune Cell Spatial Coordinates | | 鲍曼不动杆菌的“大逃亡”：膜蛋白如何与纤维连接蛋白相互作用以逃避免疫系统。 | Vasseur, L. | PDF | N/A | Acinetobacter baumannii's Great Escape: How a Membrane Protein Interacts with Fibronectin to Evade Immunity. | | 祖源相关的基质变异影响乳腺上皮细胞的侵袭能力 | Schmidtmann, M. | PDF | N/A | Ancestry-linked stromal variations impact breast epithelial cell invasion | | 较长的刺激间隔时间能增强自动化相位靶向听觉刺激对程序性记忆巩固的效果。 | Kasties, V. | PDF | N/A | Longer Interstimulus Intervals Enhance Efficacy of Automated Phase-Targeted Auditory Stimulation on Procedural Memory Consolidation | | 扩展的候选顺式调控元件注册表，用于研究转录调控 | Moore, J. E. | PDF | N/A | An Expanded Registry of Candidate cis-Regulatory Elements for Studying Transcriptional Regulation | | 调节外周神经活动：长时间低强度超声用于大鼠坐骨神经的受控兴奋与抑制 | Badawe, H. | PDF | N/A | Modulating Peripheral Neural Activity: Prolonged Low-Intensity Ultrasound for Controlled Excitation and Suppression in Rat Sciatic Nerve | | 针对JN.1或KP.2变种进行适配的mRNA-1273疫苗，在小鼠中能够引发对SARS-CoV-2的JN.1亚系产生交叉中和反应。 | Lee, D. W. | PDF | N/A | mRNA-1273 vaccines adapted to JN.1 or KP.2 elicit cross-neutralizing responses against the JN.1 sublineages of SARS-CoV-2 in mice | | 成纤维细胞的机械感知指导肺发育和模式特异性基因表达程序 | Miller, A. E. | PDF | N/A | Fibroblast mechanoperception instructs pulmonary developmental and pattern specification gene expression programs | | 集体行为的破坏与互动效率的降低相关 | Nguyen, J. B. | PDF | N/A | Disruption of Collective Behavior Correlates with Reduced Interaction Efficiency | | 由烟草花叶病毒外壳蛋白模板化的扩展等离子体纳米结构 | Abu-Baker, I. | PDF | N/A | Extended Plasmonic Nanostructures Templated by Tobacco Mosaic Virus Coat Protein | | 使用MetHMMDb快速准确地检测金属抗性基因 | Ciuchcinski, K. | PDF | N/A | Fast and accurate detection of metal resistance genes using MetHMMDb | | 上皮通过泡沫几何不稳定性诱导的成核和生长进行分层 | Fukamachi, S. | PDF | N/A | Epithelium Stratifies via Nucleation and Growth Induced by Foam-Geometric Instability | | 靶向原发性和转移性卵巢癌，使用源自人类NAF-1/CISD2蛋白的多肽 | Neumann, E. | PDF | N/A | Targeting primary and metastatic ovarian cancer with a peptide derived from the human NAF-1/CISD2 protein | | 雌激素通过增加癌细胞的胞葬作用来建立免疫抑制的肿瘤微环境。 | Chakraborty, B. | PDF | N/A | Estrogens increase cancer cell efferocytosis to establish an immunosuppressive tumor microenvironment | | 快速肌球蛋白结合蛋白-C是年轻和老年快速骨骼肌稳态的重要调节因子 | Baby, A. | PDF | N/A | Fast Myosin Binding Protein-C is a Vital Regulator in Young and Aged Fast Skeletal Muscle Homeostasis | | PrecisionTrack：在复杂环境中长期可靠地追踪大规模互动动物群体 | Coulombe, V. | PDF | N/A | PrecisionTrack: Reliable Tracking of Large Groups of Animals Interacting in Complex Environments Over Extended Periods | | 视觉遮挡对视觉诱发晕动症的影响 | aihara, t. | PDF | N/A | The Effect of Visual Field Occlusion on Visually Induced Motion Sickness | | 利用跨皮层深度延迟模式区分fMRI时间序列中的BOLD与非BOLD信号 | Chen, J. E. | PDF | N/A | Differentiating BOLD and non-BOLD signals in fMRI time series using cross-cortical depth delay patterns | | 一种热响应性塌陷系统，用于控制异质细胞的定位、比例和相互作用，以实现三维实体肿瘤建模。 | Orange, J. S. | PDF | N/A | A Thermo-responsive collapse system for controlling heterogeneous cell localization, ratio and interaction for three-dimensional solid tumor modeling | | CDH3-AS1 反义RNA通过增强P-钙黏蛋白的翻译在黑色素瘤中发挥肿瘤抑制作用。 | Chadourne, M. | PDF | N/A | CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma | | 抑制线粒体分裂蛋白Drp1可改善杜氏肌营养不良症D2-mdx模型中的肌病 | Rosen, H. G. | PDF | N/A | Inhibition of Mitochondrial Fission Protein Drp1 Ameliorates Myopathy in the D2-mdx Model of Duchenne Muscular Dystrophy | | 通过占据大型谷氨酸脱氢酶中的底物结合口袋，实现三级和四级结构的重塑。 | Lazaro, M. | PDF | N/A | Tertiary and quaternary structure remodeling by occupancy of the substrate binding pocket in a large glutamate dehydrogenase | | 溶酶体中的还原硫醇对小鼠胚胎发育至关重要。 | Adelmann, C. H. | PDF | N/A | Lysosomal reduced thiols are essential for mouse embryonic development | | 对单个线粒体组件的结构-功能异质性进行定量分析，揭示了小型线粒体网络在启动肿瘤转化中的早期作用。 | Saini, M. | PDF | N/A | Quantitative analyses of structure-function heterogeneity of individual mitochondrial components reveal an early role of small-mitochondrial-networks in priming neoplastic transformation | | 靶向解卷积一种通过VDAC1作用于β细胞并具有独特转录组特征的胰岛素分泌过多诱导剂 | Roy, G. | PDF | N/A | Target deconvolution of an insulin hypersecretion-inducer acting through VDAC1 with a distinct transcriptomic signature in beta-cells | | 山羊足骨出生后发育及骨骺闭合的动态变化 | Panebianco, C. J. | PDF | N/A | Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod | | 群体基因组学揭示犬心丝虫在犬科动物中的古老起源 | Power, R. I. | PDF | N/A | Population genomics reveals an ancient origin of heartworms in canids | | 亚洲蜗牛（学名：Bradybaena similaris，属于柄眼目：坚螺科）的染色体水平基因组组装 | Ishii, Y. | PDF | N/A | Chromosome-level genome assembly of the Asian tramp snail Bradybaena similaris (Stylommatophora: Camaenidae) | | GP-ML-DC：一种基于集成机器学习的基因组预测方法，采用分治技术实现自动两阶段降维 | Liu, Q. | PDF | N/A | GP-ML-DC: An Ensemble Machine Learning-Based Genomic Prediction Approach with Automated Two-Phase Dimensionality Reduction via Divide-and-Conquer Techniques | | 一种实用的DNA数据存储方法，通过引入5-甲基胞嘧啶扩展字母表 | Liu, D. | PDF | N/A | A practical DNA data storage using expanded alphabet introducing 5-methylcytosine | | IL-1β驱动的NF-κB转录ACE2作为SARS-CoV-2感染巨噬细胞的机制

这段文字描述了一种机制，即通过IL-1β（一种炎症因子）激活NF-κB（一种转录因子），进而促进ACE2（血管紧张素转换酶2）的转录。ACE2是SARS-CoV-2病毒进入细胞的关键受体。这一机制解释了SARS-CoV-2如何感染巨噬细胞（一种免疫细胞）。 | Lee, C. | PDF | N/A | IL-1β-driven NF-κB transcription of ACE2 as a Mechanism of Macrophage Infection by SARS-CoV-2 |

BioRxiv 2024-12-25 Papers

标题	作者	PDF链接	代码仓库	Title
较高的基础肿瘤免疫活性结合全身免疫反应可改善肝癌的预后。	Alipour Talash, G.	PDF	N/A	Higher basal tumor immune activity coupled with a systemic immune response improves liver cancer outcomes
神经血管耦合反过来调节情绪	Ruan, J.	PDF	N/A	Neurovascular coupling conversely modulates emotion
Pu.1/Spi1的剂量控制着斑马鱼和哺乳动物中小胶质细胞的更新与维持。	Wu, Y.	PDF	N/A	Pu.1/Spi1 dosage controls the turnover and maintenance of microglia in zebrafish and mammals
通过DNA初免-蛋白加强策略增强针对构象非RBD区域的抗体反应，可引发对SARS-CoV-2变种的广泛交叉中和作用。	Ma, Y.-F.	PDF	N/A	Enhanced Antibody Response to the Conformational Non-RBD Region via DNA Prime-Protein Boost Elicits Broad Cross-Neutralization Against SARS-CoV-2 Variants
广义哈代-温伯格（GH）模型解决了分子进化中的诸多悖论	Ruan, Y.	PDF	N/A	The Generalized Haldane (GH) model of genetic drift resolving the many paradoxes of molecular evolution
一种研究小麦赤霉病复合体形成过程中多物种相互作用的实验方法。	Corrales Gutierrez, M. A.	PDF	N/A	An experimental approach to study multi-species interactions implicated in Fusarium-Head Blight complex assembly in wheat.
胎盘疟疾与人类胎盘组织中的TLR-内皮素-3-氧化损伤反应相关。	Chenge, S.	PDF	N/A	Placental malaria is associated with a TLR-Endothelin-3-oxidative damage response in human placenta tissues
外泌体miRNA-124通过调节CD45的替代剪接参与宫颈癌的免疫调控。	Liang, M.	PDF	N/A	Exosomal miRNA-124 is involved in the immune regulation of cervical cancer by regulating CD45 alternative splicing
外泌体miRNA-124通过调控CD45的可变剪接参与宫颈癌的免疫调节。	Liang, M.	PDF	N/A	Exosomal miRNA-124 is involved in the immune regulation of cervical cancer by regulating CD45 alternative splicing
谷胱甘肽对暴露于850-1900 MHz手机辐射的小鼠肝酶和血清电解质的影响	Binhambali, A.	PDF	N/A	Glutathione Effects on Liver Enzymes and Serum Electrolyte in Mice Exposed to 850 1900 MHz Mobile Phone Radiation
两个远缘果蝇物种在变态过程中基因表达的时间动态	Ozerova, A. M.	PDF	N/A	Temporal dynamics of gene expression during metamorphosis in two distant Drosophila species
揭示小鼠血清淀粉样蛋白A3在动脉粥样硬化进展过程中对主动脉免疫细胞亚群的免疫学作用	Chou, T.-Y.	PDF	N/A	Unraveling the immunological roles of murine serum amyloid A3 in aortic immune cell subsets during atherosclerosis progression
BA.2.86的早期演化揭示了高度分化的SARS-CoV-2谱系的起源	Escalera-Zamudio, M.	PDF	N/A	Early evolution of BA.2.86 sheds light on the origins of highly divergent SARS-CoV-2 lineages
在Scn8a功能增益小鼠中，持续的Na+电流将癫痫发作与扩散性去极化耦合在一起。	Aiba, I.	PDF	N/A	Persistent Na+ current couples seizure with spreading depolarization in Scn8a gain of function mice
在鼠类临床前肺部感染模型中，O特异性抗原的缺失塑造了铜绿假单胞菌种群的微生物地理分布。	Fraser, H.	PDF	N/A	Loss of O-specific antigen shapes Pseudomonas aeruginosa population microbiogeography in murine preclinical pulmonary infection model
基因组语言模型的局限性与增强：动态选择方法	Qiu, S.	PDF	N/A	Limitations and Enhancements in Genomic Language Models: Dynamic Selection Approach
能量变化预测冈比亚按蚊的死亡率	Zeferino, T. G.	PDF	N/A	Energetic shifts predict the mortality of Anopheles gambiae
跨睡眠阶段的时程解析神经振荡：与睡眠质量和衰老的关联	Passaro, A. D.	PDF	N/A	Time-Resolved Neural Oscillations Across Sleep Stages: Associations with Sleep Quality and Aging
细菌表面的血红素结合DNA结构促进细胞外电子传递	Ajunwa, O. M.	PDF	N/A	Hemin-binding DNA structures on the surface of bacteria promote extracellular electron transfer
通过泛素蛋白酶体系统实现孢子体导向的配子发生	Sivakumar, P.	PDF	N/A	Sporophyte Directed Gametogenesis via the Ubiquitin Proteasome System
生物分子凝聚体控制并定义了病毒复制过程中产生的RNA-RNA相互作用。	Aierken, D.	PDF	N/A	Biomolecular condensates control and are defined by RNA-RNA interactions that arise in viral replication
长读长测序揭示了双壳类动物线粒体基因组中存在广泛的尺寸变异，并暗示了其扩展的进化模式。	Zhang, N.	PDF	N/A	Long-read sequencing reveals extensive size variation and suggests evolutionary patterns of expansion in bivalve mitogenomes
致病性错义突变对Menin蛋白功能的动态介导效应的分子机制	Zhang, Q.	PDF	N/A	Molecular mechanisms of dynamics-mediated effects of pathogenic missense mutations on Menin protein function
新生RNA分析揭示了细菌通过高效重复起始对基因转录的调控。	Sun, Z.	PDF	N/A	Nascent RNA profiling reveals regulation of gene transcription through productive reiterative initiation in bacteria
以下是这段英文的中文翻译：

"在恒河猴成年期，基于血液的神经退行性变和炎症生物标志物的表达模式"

翻译说明： 1. "Expression patterns" 翻译为 "表达模式" 2. "blood-based biomarkers" 翻译为 "基于血液的生物标志物" 3. "neurodegeneration" 翻译为 "神经退行性变" 4. "inflammation" 翻译为 "炎症" 5. "across adulthood" 翻译为 "在成年期" 6. "rhesus macaques" 翻译为 "恒河猴"

这个翻译准确地传达了原文的意思，描述了在恒河猴成年期，通过血液检测来研究神经退行性变和炎症相关生物标志物的表达变化的研究内容。 | Metzler, L. A. P. | PDF | N/A | Expression patterns of blood-based biomarkers of neurodegeneration and inflammation across adulthood in rhesus macaques | | 线虫衰老过程中线粒体成像策略的交叉比较。 | Kim, J. | PDF | N/A | Cross comparison of imaging strategies of mitochondria in C. elegans during aging. | | 在人类世时期，全球授粉者生物多样性的下降。 | Kallivalappil, R. | PDF | N/A | The decline of global pollinator biodiversity in the Anthropocene | | 脂肪酸硫酯酶A与129个片段结合的晶体结构为多样化的发展机会提供了基础。 | Kot, E. | PDF | N/A | Crystal structure of Fatty Acid Thioesterase A bound by 129 fragments provides diverse development opportunities | | 通过整合生物信息学方法对小鼠肿瘤细胞的差异表达基因进行鉴定与分析 | Jing, X. | PDF | N/A | Identification and analysis of DEGs of mouse tumor cells by integrated bioinformatics methods | | Isopeptor：一种用于检测蛋白质结构中分子内异肽键的工具 | Costa, F. | PDF | N/A | Isopeptor: a tool for detecting intramolecular isopeptide bonds in protein structures | | 炎症在人源化小鼠模型中转甲状腺素蛋白心脏淀粉样变性的作用 | Wu, X. | PDF | N/A | The role of inflammation in a humanized mouse model of transthyretin cardiac amyloidosis | | 支持近端结肠运动复合体节律性启动新假说的实验数据 | Morales-Soto, W. | PDF | N/A | Experimental data supporting a novel hypothesis for the rhythmic initiation of proximal colon motor complexes | | 利用体细胞超突变在人体细胞中进行无病毒持续定向进化 | Bram, S. | PDF | N/A | Virus-free continuous directed evolution in human cells using somatic hypermutation | | WWOX基因缺陷会损害人类类器官中的神经发生和神经元功能。 | Steinberg, D. J. | PDF | N/A | WWOX deficiency impairs neurogenesis and neuronal function in human organoids | | 解剖到束路映射：无需扩散流线传播推断白质路径 | Tan, Y.-F. | PDF | N/A | Anatomy-to-Tract Mapping: Inferring White Matter Pathways Without Diffusion Streamline Propagation | | Afadin缺失的视网膜表现出严重的神经元层化缺陷，但仍保留视觉功能。 | Ueno, A. | PDF | N/A | Afadin-deficient retinas exhibit severe neuronal lamination defects but preserve visual functions | | 不同的皮层群体驱动多感官调节分离的听觉源 | Cai, H. | PDF | N/A | Distinct cortical populations drive multisensory modulation of segregated auditory sources | | Afadin将不同类型的视网膜神经元精确分类至相应的细胞层中。 | Lum, M. R. | PDF | N/A | Afadin Sorts Different Retinal Neuron Types into Accurate Cellular Layers | | 全面分析小RNA及其在精神分裂症和双相情感障碍中的变化及其与mRNA的关联 | Nersisyan, S. | PDF | N/A | Comprehensive profiling of small RNAs and their changes and linkages to mRNAs in schizophrenia and bipolar disorder | | 在持续性病毒感染期间，CD4 T细胞非依赖性的IgG反应有利于中和逃逸变异株的出现。 | Ayers, K. N. | PDF | N/A | The CD4 T cell-independent IgG response during persistent virus infection favors emergence of neutralization-escape variants | | 在可检测到的HIV-1反弹病毒血症之前，炎症性单核细胞数量增加。 | Farrell-Sherman, A. | PDF | N/A | Inflammatory Monocytes Increase Prior to Detectable HIV-1 Rebound Viremia | | 玉米及其野生近缘种在多倍体化后表现出明显的基因组缩减模式。 | Snodgrass, S. J. | PDF | N/A | Maize and wild relatives show distinct patterns of genome downsizing following polyploidy | | 了解绵羊跟骨附着点的结构和力学特性：一种适用于组织工程应用的相关动物模型 | Sensini, A. | PDF | N/A | Understanding the structure and mechanics of the sheep calcaneal enthesis: a relevant animal model for tissue engineering applications | | 通过对感染无毒和有毒结核分枝杆菌的巨噬细胞进行综合分析，揭示了不同的免疫机制及处理后的外泌体的抗结核作用。 | Yang, L. | PDF | N/A | Comprehensive analysis of macrophages infected with avirulent and virulent Mycobacterium tuberculosis uncovers distinct immune mechanisms and anti-TB effect of treated exosomes | | 单细胞分析揭示小鼠表皮肿瘤进展过程中的全局免疫反应 | Fan, X. | PDF | N/A | Single-Cell Profiling Reveals Global Immune Responses during the Progression of Murine Epidermal Neoplasms | | 基质导向药物联合化疗对胰腺癌的疗效——一项临床前研究 | Gupta, M. | PDF | N/A | Effect of Stroma-directed Drugs in Combination with Chemotherapy Against Pancreatic Cancer- a Preclinical Study | | 在对抗行为偏见的趋近-回避结果转换中，中型棘状神经元亚型的瞬时多巴胺反应——行动选择探索的框架

这段翻译成中文的意思是：在研究如何克服行为偏见，实现趋近与回避结果之间的转换时，中型棘状神经元的不同亚型会表现出短暂的多巴胺反应。这一现象为探索行动选择提供了一个理论框架。 | Anisetty, N. | PDF | N/A | Transient dopamine response on medium spiny neuron subtypes in switching approach-avoidance outcomes against action bias - A framework for exploration in action selection | | 在尼日利亚伊巴丹，缓慢生长的伤寒沙门氏菌被误鉴定为鸡沙门氏菌。 | Sunmonu, G. T. | PDF | N/A | Slow-growing Salmonella enterica Typhi mis-identified as Salmonella Gallinarum in Ibadan, Nigeria | | 受人类凝集素启发的聚糖分析探针用于研究宿主-微生物相互作用 | Ghosh, S. | PDF | N/A | Glycan analysis probes inspired by human lectins for investigating host-microbe crosstalk | | 结构导向的α-酮异己酸双加氧酶工程提高了集胞藻PCC 6803中异丁烯的产量 | Schumann, C. | PDF | N/A | Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803 | | CorrAdjust通过高效消除隐藏的混杂因素，揭示了具有生物学意义的转录组相关性。 | Nersisyan, S. | PDF | N/A | CorrAdjust unveils biologically relevant transcriptomic correlations by efficiently eliminating hidden confounders | | 基于几何的BERT：一种经过实验验证的深度学习模型，用于药物发现中的分子性质预测 | Zhang, X. | PDF | N/A | Geometry-based BERT: an experimentally validated deep learning model for molecular property prediction in drug discovery | | 海马神经元中STIM1和STIM2在ER-PM接触位点的活动依赖性定位及异质性动力学。 | Chhikara, A. | PDF | N/A | Activity-Dependent Localization and Heterogeneous Dynamics of STIM1 and STIM2 at ER-PM contacts in Hippocampal Neurons. | | Prohibitin 2 是体内 T 细胞增殖、分化和效应功能的关键调节因子。 | Vogt, J. F. | PDF | N/A | Prohibitin 2 is a Key Regulator of T Cell Proliferation, Differentiation, and Effector Functions in vivo | | 了解遗传结构有助于克服种子质量与抗虫性之间的权衡关系。 | White, J. R. | PDF | N/A | Understanding genetic architecture overcomes tradeoffs between seed quality and insect resistance | | 系统性评估高通量亚细胞空间转录组学平台 | Ren, P. | PDF | N/A | Systematic Benchmarking of High-Throughput Subcellular Spatial Transcriptomics Platforms | | 使用样本定制的最小化文库进行精确且可扩展的宏基因组分析 | Nystrom-Persson, J. | PDF | N/A | Precise and scalable metagenomic profiling with sample-tailored minimizer libraries | | 基于长短期记忆网络的土地利用类型演变预测方法——以甘肃省为例 | Zhang, S. | PDF | N/A | A Prediction Method of Land Use Type Evolution Based on Long and Short-Term Memory Networks--Taking Gansu Province as an Example | | 基于表型相关标记基因在群体和单细胞中的表达谱推断单细胞的表型 | He, Y. | PDF | N/A | Inferring phenotypes of single cells based on the expression profiles of phenotype-associated marker genes in bulks and single cells | | dGAMLSS：一种精确的分布式算法，用于拟合位置、尺度和形状的广义加性模型，以生成隐私保护的人口参考图表 | Hu, F. | PDF | N/A | dGAMLSS: An exact, distributed algorithm to fit Generalized Additive Models for Location, Scale, and Shape for privacy-preserving population reference charts | | 横纹肌肉瘤的双读出斑马鱼胚胎异种移植模型，用于评估临床相关的多受体酪氨酸激酶抑制剂 | Wragg, J. W. | PDF | N/A | A dual readout embryonic zebrafish xenograft model of rhabdomyosarcoma to assess clinically relevant multi-receptor tyrosine kinase inhibitors | | 利用无标记多模态非线性光学成像技术对前列腺导管内癌进行纹理分析分类 | Gagnon, J. R. | PDF | N/A | Texture-Analysis Classification of Intraductal Carcinoma of the Prostate Using Label-Free Multimodal Nonlinear Optical Imaging | | 过量表达叶黄素循环基因导致C4单子叶植物绿狗尾草更快适应非光化学淬灭（NPQ） | Stone, W. D. | PDF | N/A | Overexpression of Xanthophyll Cycle Genes Leads to Faster NPQ Acclimation in the C4 Monocot Setaria viridis | | 对性传播寄生虫阴道毛滴虫（Trichomonas vaginalis）的比较基因组学分析揭示了其进化过程中的松弛与趋同现象，以及涉及从鸟类向人类传播的关键基因。 | Sullivan, S. A. | PDF | N/A | Comparative genomics of the sexually transmitted parasite Trichomonas vaginalis reveals relaxed and convergent evolution and genes involved in spillover from birds to humans | | 在芬兰大饥荒期间，繁殖的寿命成本增加了。 | Young, E. A. | PDF | N/A | Lifespan costs of reproduction increase during the Great Finnish Famine | | 选择性离子结合与摄取塑造了生物分子凝聚体的微环境 | Smokers, I. B. A. | PDF | N/A | Selective ion binding and uptake shape the microenvironment of biomolecular condensates | | 剖析髓鞘再生微环境中不断演变的细胞景观 | Melchor, G. S. | PDF | N/A | Dissecting the evolving cellular landscape of a remyelinating microenvironment | | 光遗传学方法在脂质双层上组装肌动蛋白网络揭示了肌动蛋白结合蛋白的网络密度依赖性功能 | Yamamoto, K. | PDF | N/A | Optogenetic actin network assembly on lipid bilayer uncovers the network density-dependent functions of actin-binding proteins | | 比较体外急性和慢性暴露下，全氟辛酸（PFOA）对人血管内皮细胞的顶端和转录组学效应点的敏感性差异 | Opacic, M. | PDF | N/A | Comparative sensitivity of in vitro acute and chronic apical and transcriptomic points of departure for perfluorooctanoic acid in human vascular endothelial cells | | 利用果蝇模型探索AI生成合成肽在提升蜜蜂健康与抵抗力方面的潜力 | Sun, Y. | PDF | N/A | Leveraging Drosophila Models to Explore AI-generated Synthetic Peptide's Potential in Boosting Honeybee Health and Resilience | | ChromBPNet：基于偏差分解、碱基分辨率的深度学习模型揭示染色质可及性中的顺式调控序列语法、转录因子足迹及调控变异

一种用于小鼠尾部情境依赖性运动控制的前庭脊髓通路

解释： - vestibulospinal pathway：前庭脊髓通路，指的是从前庭系统到脊髓的神经传导路径，参与姿势和运动的调节。 - context-dependent：情境依赖性，表示行为或反应会根据具体情境而变化。 - motor control：运动控制，指神经系统对肌肉活动的调节。 - mouse tail：小鼠尾部，指的是实验中小鼠的尾巴。

"南美洲鼠类系统发育基因组学：云雾林和上新世灭绝事件解释了南美洲小鼠和大鼠辐射的时间和扩散"

翻译说明： 1. "Phylogenomics" 译为 "系统发育基因组学"，这是一个结合基因组学和系统发育学的交叉学科。 2. "sigmodontine rodents" 译为 "南美洲鼠类"，指代南美洲特有的一个啮齿动物类群。 3. "Cloud forests" 译为 "云雾林"，指热带和亚热带地区的高海拔森林生态系统。 4. "Pliocene extinction" 译为 "上新世灭绝事件"，指地质年代上新世时期发生的大规模生物灭绝事件。 5. "radiation" 译为 "辐射"，在生物学中指的是一个类群快速分化和多样化的过程。

整句话的意思是：通过系统发育基因组学研究南美洲鼠类的演化历史，发现云雾林的分布和上新世灭绝事件共同解释了这类啮齿动物快速分化的时间进程和地理扩散模式。

"人类内皮细胞和血管平滑肌细胞中基因表达的全局和遗传调控"

翻译解释： - "Global" 在这里指的是“全局的”或“整体的”，表示对基因表达的全面或广泛的研究。 - "Genetic regulation" 指的是“遗传调控”，即基因如何被调控以影响其表达。 - "Gene expression" 是“基因表达”，指的是基因信息被转化为功能蛋白质或 RNA 的过程。 - "Human endothelial and vascular smooth muscle cells" 是“人类内皮细胞和血管平滑肌细胞”，这两种细胞在血管结构和功能中起重要作用。

在这段翻译中，"Nectin-4 PET" 指的是一种利用正电子发射断层扫描（PET）技术来检测Nectin-4表达的方法，Nectin-4是一种在某些癌症中表达的蛋白质。"Enfortumab Vedotin" 是一种针对Nectin-4的抗体药物偶联物，用于治疗尿路上皮癌。"剂量反应" 指的是药物剂量与治疗效果之间的关系。因此，整句话的意思是使用Nectin-4 PET技术来优化Enfortumab Vedotin在尿路上皮癌治疗中的剂量，以达到最佳的治疗效果。 | Mishra, A. | PDF | N/A | Nectin-4 PET For Optimizing Enfortumab Vedotin Dose-Response In Urothelial Carcinoma | | 越南木荷（Schima wallichii (DC.) Korth）中的山柰酚-3-O-鼠李糖苷对人类白血病细胞的细胞毒性活性：体外与计算机模拟的联合研究

BioRxiv 2024-12-24 Papers

标题	作者	PDF链接	代码仓库	Title
自然选择塑造了鸟类和哺乳动物的种群动态。	Witting, L.	PDF	N/A	Natural selection shapes the population dynamics of birds and mammals
由疾病相关突变揭示的小热休克蛋白HSPB5的激活机制。	Woods, C. N.	PDF	N/A	Activation mechanism of Small Heat Shock Protein HSPB5 revealed by disease-associated mutants.
营养卵影响蚂蚁Pogonomyrmex rugosus的种姓决定	Genzoni, E.	PDF	N/A	Trophic eggs affect caste determination in the ant Pogonomyrmex rugosus
脂质双层增强膜蛋白的协作网络	Muhammednazaar, S.	PDF	N/A	Lipid Bilayer Strengthens the Cooperative Network of Membrane Proteins
常见变异对人类大脑基因表达的影响：从RNA到蛋白质再到精神分裂症风险	Liang, Q.	PDF	N/A	The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk
狼鳍鱼化石中的古DNA：进化关键发现与方法论再评估	Zhao, W.	PDF	N/A	Ancient DNA in Lycoptera Fossils: Key Discoveries for Evolution and Methodological Reassessment
通过前馈-循环回路的对齐，连贯的皮层表征在经验后得以发展。	Lempel, A. A.	PDF	N/A	Coherent cortical representations develop after experience via feedforward-recurrent circuit alignment
对侧海马扩散性去极化促进卒中后功能恢复	Boyce, A. K.	PDF	N/A	Contralesional hippocampal spreading depolarization promotes functional recovery after stroke
Spotiflow：基于深度立体流回归的荧光显微镜精确高效斑点检测

解释： - "Spotiflow" 是工具或方法的名称，保留不变。 - "accurate and efficient" 翻译为“精确高效”，强调方法的准确性和效率。 - "spot detection" 翻译为“斑点检测”，指的是在图像中识别和定位斑点的过程。 - "fluorescence microscopy" 翻译为“荧光显微镜”，指的是使用荧光技术进行显微观察的方法。 - "deep stereographic flow regression" 翻译为“深度立体流回归”，指的是使用深度学习技术进行立体流回归分析的方法。

整体翻译传达了原文的核心内容，同时保持了专业术语的准确性。 | Mantes, A. D. | PDF | N/A | Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression | | 阿片类药物诱导的风险行为在前边缘前额叶皮层的神经特征 | Quave, C. B. | PDF | N/A | Neural signatures of opioid-induced risk-taking behavior in the prelimbic prefrontal cortex | | 相同句子，不同语法，不同大脑反应：一项关于印地语和尼泊尔语分裂作格结构中格与一致性编码的脑磁图研究 | Chacon, D. A. | PDF | N/A | Same Sentences, Different Grammars, Different Brain Responses: An MEG study on Case and Agreement Encoding in Hindi and Nepali Split-Ergative Structures | | 纹状体动作选择与强化学习的动态机制 | Lindsey, J. | PDF | N/A | Dynamics of striatal action selection and reinforcement learning | | 结合无线电遥测和雷达测量技术，测试一种空中食虫鸟类的优化觅食行为 | Bloch, I. | PDF | N/A | Combining radio-telemetry and radar measurements to test optimal foraging in an aerial insectivore bird | | 通过外部切趾相位对比显微镜对活体哺乳动物细胞内的结构进行无标记成像 | Ohno, H. | PDF | N/A | Label-free imaging of intracellular structures in living mammalian cells via external apodization phase-contrast microscopy | | 根瘤菌效应因子NopT靶向结瘤因子受体以调控百脉根中的共生关系 | Bao, H. | PDF | N/A | The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus | | Kv2.2通道介导前列腺素E2对胰腺β细胞中葡萄糖刺激的胰岛素分泌的抑制作用。 | Pan, C. | PDF | N/A | The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells | | 阈下经颅磁刺激对桡侧腕屈肌长潜伏期反应的抑制作用 | Helm, C. A. | PDF | N/A | Inhibitory Effect of Subthreshold TMS on the Long-latency Response in the Flexor Carpi Radialis | | 细胞外囊泡主要通过整合素和GM1与层粘连蛋白的相互作用粘附在细胞上。 | Isogai, T. | PDF | N/A | Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin | | 肠道胶质细胞调控潘氏细胞分泌及肠道微生物生态 | Prochera, A. | PDF | N/A | Enteric glia regulate Paneth cell secretion and intestinal microbial ecology | | 食品添加剂二氧化钛对免疫活性细胞的靶向作用 | Wills, J. W. | PDF | N/A | Immunocompetent Cell Targeting by Food-Additive Titanium Dioxide | | 需要一个由δ-微管蛋白/ε-微管蛋白/Ted蛋白组成的复合物来维持中心粒的结构。 | Pudlowski, R. | PDF | N/A | A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture | | 拯救DNMT1未能完全逆转其在小鼠胚胎干细胞中缺失的分子和功能影响 | Elder, E. | PDF | N/A | Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells | | 由GABA能、谷氨酸能和章鱼胺能神经元介导的非自主性UPRER的独特机制。 | Coakley, A. J. | PDF | N/A | Distinct mechanisms of non-autonomous UPRER mediated by GABAergic, glutamatergic, and octopaminergic neurons. | | 端到端神经网络的挑战性冷冻电镜和冷冻电子断层扫描数据集从头重建 | Levy, A. | PDF | N/A | End-to-end neural ab initio reconstruction of challenging cryo-EM and cryo-ET datasets | | 多种毒素展现出与烟碱型乙酰胆碱受体的共同结合模式，揭示了一种新的分子决定因素。 | Do, H. N. | PDF | N/A | Diverse toxins exhibit a common binding mode to the Nicotinic Acetylcholine Receptors revealing a new molecular determinant | | 水禽的延迟二色性作为评估生命率的便捷工具 | Tableau, A. | PDF | N/A | Delayed dichromatism in waterfowl as a convenient tool for assessing vital rates | | 多巴胺能够增加海马神经元的蛋白质合成，从而促进多巴胺依赖的长时程增强（LTP）。 | Fuchsberger, T. | PDF | N/A | Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTP | | 尽管存在竞争，但仍能共存：植被结构复杂性对演替过程中苔藓植物多样性的影响。 | Hanusch, M. | PDF | N/A | Coexistence despite competition: Effects of vegetation structural complexity on bryophyte diversity over succession. | | 生态进化引导的病理组学分析用于预测导管原位癌升级 | Xiao, Y. | PDF | N/A | Eco-evolutionary Guided Pathomic Analysis to Predict DCIS Upstaging | | 揭示纳木错湖中隐藏的RNA病毒多样性：来自极端高海拔环境的进化洞见 | Wu, L. | PDF | N/A | Uncovering the hidden RNA virus diversity in Lake Nam Co: evolutionary insights from an extreme high-altitude environment | | 淀粉样变性轻链的构象指纹。 | Paissoni, C. | PDF | N/A | A conformational fingerprint for amyloidogenic light chains. | | T3SS转位子通过直接与NLRC4/NAIP炎症小体相互作用诱导细胞焦亡。 | Zhao, Y. | PDF | N/A | T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome | | 在基于长梯度折射率（GRIN）透镜的显微内窥镜中进行像差校正，以实现深部脑区域的扩展视野双光子成像 | Sattin, A. | PDF | N/A | Aberration correction in long GRIN lens-based microendoscopes for extended field-of-view two-photon imaging in deep brain regions | | 节丛孢菌（Arthrobotrys oligospora）的线虫捕捉装置是一种适应温度变化的铁储存表型

翻译说明： - Nematode-Trapping Devices：线虫捕捉装置，指的是节丛孢菌用于捕捉线虫的特殊结构。 - Arthrobotrys oligospora：节丛孢菌，是一种能够捕捉线虫的真菌。 - Iron Storage Phenotype：铁储存表型，指该真菌在特定条件下表现出储存铁的特性。 - Adapted to Temperature Changes：适应温度变化，表明这种表型能够随着温度的变化而调整。

这段翻译将英文标题“The Restoration of Social Defects in Schizophrenic Mice by Plant Exposure”转化为中文，同时保持了原文的学术性和专业性。标题中的“Restoration”翻译为“恢复作用”，强调了植物暴露对精神分裂症小鼠社会缺陷的积极影响。“Social Defects”翻译为“社会缺陷”，指的是小鼠在社交行为上的异常或障碍。“Schizophrenic Mice”翻译为“精神分裂症小鼠”，指的是用于研究精神分裂症的动物模型。“Plant Exposure”翻译为“植物暴露”，指的是小鼠与植物的接触或处于植物环境中的情况。整个标题清晰地传达了研究的核心内容，即通过植物暴露来恢复精神分裂症小鼠的社会缺陷。 | Li, M. | PDF | N/A | The Restoration of Social Defects in Schizophrenic Mice by Plant Exposure | | 弹性蛋白酶介导的脑小血管病中的白质损伤：小胶质细胞与中性粒细胞的双人舞

这段翻译保留了原文的科学性和专业性，同时确保了中文表达的准确性和流畅性。翻译中，“VSIG4-Expressing Macrophages”被译为“表达VSIG4的巨噬细胞”，直接传达了原文中巨噬细胞表达VSIG4蛋白的信息。“Contribute To”译为“在……中起作用”，符合中文表达习惯，同时也准确传达了原文中巨噬细胞在特定生理过程中的作用。“Anti-Parasitic And Anti-Metastatic Responses”被译为“对抗寄生虫和抗转移反应”，清晰地表达了巨噬细胞在腹膜腔中的两种主要功能。“Peritoneal Cavity”译为“腹膜腔”，是医学术语，确保了翻译的专业性。整体翻译既忠实于原文，又符合中文表达习惯，易于理解。 | Van Ginderachter, J. A. | PDF | N/A | VSIG4-Expressing Macrophages Contribute To Anti-Parasitic And Anti-Metastatic Responses In The Peritoneal Cavity | | 在卡波西肉瘤相关疱疹病毒（KSHV）感染期间，干扰素-β（Interferon-β）的诱导异质性是由干扰素-β增强体（enhanceosome）转录因子而非IRF3决定的。 | Kaku, M. | PDF | N/A | Interferon-β induction heterogeneity during KSHV infection is determined by interferon-β enhanceosome transcription factors other than IRF3 | | 对于小立碗藓（Physcomitrium patens）原丝体发育至关重要的过程，需要由功能冗余的PpROP GTPases提供的不同水平的总活性。 | Le Bail, A. | PDF | N/A | Processes essential for Physcomitrium patens protonemal development require distinct levels of total activity provided by functionally redundant PpROP GTPases | | 乳腺癌患者外周血淋巴细胞中DNA双链断裂与细胞死亡之间的相关性 | Solana-Pena, A. | PDF | N/A | Correlation between DNA double strand breaks and cell death in peripheral blood lymphocytes from breast cancer patients | | 基于规则的二萜类化合物库解构与重建：模式分类与结构景观解析

这段翻译将英文标题“Rule-Based Deconstruction and Reconstruction of Diterpene Libraries: Categorizing Patterns & Unravelling the Structural Landscape”转化为中文，同时保留了原文的专业性和准确性。翻译后的标题清晰地传达了原文的核心内容，即通过基于规则的方法对二萜类化合物库进行解构和重建，进而对化合物模式进行分类并解析其结构景观。 | Mathieu, D. | PDF | N/A | Rule-Based Deconstruction and Reconstruction of Diterpene Libraries: Categorizing Patterns & Unravelling the Structural Landscape | | YAP通过与RIF1相互作用来缓解鳞状细胞癌中的复制应激。 | Bojko, J. | PDF | N/A | YAP engages RIF1 to dampen replication stress in squamous cell carcinoma. | | 硝基化动力学失调促进亚硝化应激并导致射血分数保留型心脏代谢性心力衰竭 | Li, Z. | PDF | N/A | Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction | | 解码由RAR特异性激动剂驱动的神经元-星形胶质细胞命运转变过程中的转录身份 | Galindo-Albarran, A. | PDF | N/A | Decoding transcriptional identity during Neuron-Astroglia Cell Fate driven by RAR-specific agonists | | TSvelo：通过联合建模转录与剪接实现全面的RNA速度推断

RNA速度是一种利用未剪接和剪接mRNA的动态变化来推断细胞未来状态的技术。TSvelo方法通过同时考虑转录和剪接过程，提供了一种更全面的RNA速度推断框架。这种方法能够更准确地捕捉细胞状态的动态变化，从而在单细胞RNA测序数据分析中提供更深入的见解。 | Li, J. | PDF | N/A | TSvelo: Comprehensive RNA velocity inference by jointly modeling Transcription and Splicing | | 重新思考癌症药物协同作用预测：呼吁机器学习应用的标准化 | Wong, A. M. | PDF | N/A | Rethinking cancer drug synergy prediction: a call for standardization in machine learning applications | | 活体出血脑中的髓系细胞单细胞时间图谱 | Kawamura, Y. | PDF | N/A | Single-Cell Temporal Atlas of Myeloid Cells in the Live Haemorrhagic Brain | | 揭示石油中的古代DNA：洞察地球隐秘生命事件与地质历史 | Zhao, W.-Q. | PDF | N/A | Uncovering Ancient DNA in Petroleum: Insights into Earth Hidden Life Events and Geological History | | 这段英文翻译成中文是：“一种女巫扫帚植原体效应蛋白通过稳定植物中的bHLH转录因子来诱导矮化。” | Yang, S. | PDF | N/A | A Witches' Broom Phytoplasma effector induces stunting by stabilizing a bHLH transcription factor in plants | | 远程检测浮游水生植被的红边光谱特征 | Murakami, A. | PDF | N/A | Remote Detection of Red-Edge Spectral Characteristics in Floating Aquatic Vegetation | | 工程化改造大麦NLR中的Exo70整合结构域以增强稻瘟病抗性 | Saado, I. | PDF | N/A | Engineering an Exo70 integrated domain of a barley NLR for improved blast resistance | | 在Pink1基因敲除小鼠和野生型小鼠中，单次感染啮齿柠檬酸杆菌（Citrobacter rodentium）会导致局部血脑屏障扰动和胶质细胞激活，但不会引起多巴胺神经元轴突末端的损失。 | Mukherjee, S. | PDF | N/A | A single Citrobacter rodentium infection in Pink1 knockout and wild type mice leads to regional blood-brain-barrier perturbation and glial activation without dopamine neuron axon terminal loss | | GJB2的细胞特异性递送恢复了DFNB1耳聋小鼠模型的听觉功能，并在非人灵长类动物（NHP）耳蜗中实现了适当的表达。 | Ivanchenko, M. V. | PDF | N/A | Cell-specific delivery of GJB2 restores auditory function in mouse models of DFNB1 deafness and mediates appropriate expression in NHP cochlea | | 与行为强化相关的奖励表征的重新激活 | Tong, A. P. S. | PDF | N/A | Reactivation of reward representations associated with the reinforcement of behavior | | 新分离的基因组和全球海洋宏基因组揭示了SAR11的生态相关单元。 | Freel, K. C. | PDF | N/A | New isolate genomes and global marine metagenomes resolve ecologically relevant units of SAR11 | | 专家世界中的通才：具有广泛宿主范围的弧菌噬菌体

在这个由专家主导的世界里，弧菌噬菌体以其广泛的宿主范围脱颖而出，成为了微生物领域中的“通才”。这些噬菌体能够感染多种不同的弧菌菌株，展现出独特的适应能力和多样性。它们的存在不仅挑战了我们对宿主-噬菌体关系的传统理解，也为开发新型抗菌策略提供了宝贵的资源。通过研究这些具有广泛宿主范围的弧菌噬菌体，科学家们希望能够揭示其背后的分子机制，并探索其在控制弧菌感染、维护水生生态系统健康以及促进食品安全等方面的潜在应用。 | Bernard, C. | PDF | N/A | Generalists in a Specialist World: Vibrio-Phages with Broad Host Range | | 在长链非编码RNA DRAIC中，存在一个由可变剪接调控的36个碱基的发夹结构，该结构与IKKα的卷曲螺旋域相互作用，并抑制NF-kB及肿瘤细胞表型。 | Hao, X. | PDF | N/A | A 36-base hairpin within lncRNA DRAIC, which is modulated by alternative splicing, interacts with the IKKα coiled-coil domain and inhibits NF-kB and tumor cell phenotypes | | 香烟烟雾通过氧化应激诱导PPP1R15A，从而调节支气管上皮细胞的炎症细胞因子产生。 | Amatngalim, G. D. | PDF | N/A | Cigarette smoke induces PPP1R15A via oxidative stress to modulate inflammatory cytokine production by bronchial epithelial cells | | 恢复氧化磷酸化可增强线粒体DNA翻译缺陷的人骨髓间充质干细胞的成骨能力。 | Fernandez Guerra, P. | PDF | N/A | Restoring oxidative phosphorylation enhances osteogenesis in mitochondrial DNA translation defective human bone marrow stromal cells | | 横跨美国本土的冠层高度模型与NAIP影像对 | Allred, B. W. | PDF | N/A | Canopy height model and NAIP imagery pairs across CONUS | | 增强的多功能性和便利性：ReMOT介导的昆虫基因修饰技术的进展与策略优化 | Liang, X. | PDF | N/A | Increased versatility and convenience: advances and strategy optimization of ReMOT-mediated genetic modification in insects | | 鸡腿颜色由抑制皮肤黑色素（ID）决定，这一过程通过一种调控CDKN2A表达的结构变异来介导。 | Li, J. | PDF | N/A | Chicken shank color determined by Inhibition of dermal melanin (ID) is mediated by a structural variation regulating CDKN2A expression | | 全基因组范围内利用双链DNA脱氨酶绘制真核生物开放染色质区域图谱 | Dong, W. | PDF | N/A | Genome-wide Mapping Eukaryotic Open Chromatin Regions with Double-Stranded DNA Deaminase | | 狗基因组中的候选印记控制区域 | Wyss, P. | PDF | N/A | Candidate imprinting control regions in dog genome | | 通过体外重构研究自噬货物招募和膜扩张的机制 | Zhang, W. | PDF | N/A | Mechanistic studies of autophagic cargo recruitment and membrane expansion through in vitro reconstitution | | ISCO：用于类器官精确分割与对比分析的智能框架 | ZHOU, J. | PDF | N/A | ISCO: Intelligent Framework for Accurate Segmentation and Comparative Analysis of Organoids | | 用于批量及单细胞Hi-C数据中染色质环注释的通用工具 | Hou, Y. | PDF | N/A | A universal tool for chromatin loop annotation in bulk and single-cell Hi-C data | | 揭示诊疗潜力：深入探索无细胞微RNA-蛋白质相互作用 | Sahu, V. K. | PDF | N/A | Unveiling theranostic potential: Insights into cell-free microRNA-protein interactions | | 以下是这段英文的中文翻译：

山羊乳清蛋白源生物活性肽作为胰脂肪酶和α-淀粉酶抑制剂的蛋白质组学表征及分子机制研究

翻译说明： 1. Proteomic Characterization 翻译为“蛋白质组学表征”，指通过蛋白质组学技术对生物活性肽进行分析和鉴定。 2. Molecular Mechanism 翻译为“分子机制”，指研究生物活性肽抑制胰脂肪酶和α-淀粉酶的具体分子作用机制。 3. Goat Whey Protein-Derived Bioactive Peptides 翻译为“山羊乳清蛋白源生物活性肽”，指从山羊乳清蛋白中提取或衍生的具有生物活性的肽段。 4. Pancreatic Lipase and alpha-Amylase Inhibitors 翻译为“胰脂肪酶和α-淀粉酶抑制剂”，指这些生物活性肽具有抑制胰脂肪酶和α-淀粉酶活性的功能。

“SMARCA1被鉴定为结直肠癌的关键调控因子”

这个翻译准确表达了原文的含义，即SMARCA1在结直肠癌中扮演着重要的调控角色。 | Fu, C. | PDF | N/A | Identification of SMARCA1 as a key regulator for Colorectal Cancer | | 肝脏微循环的激光散斑成像 | Zhukov, O. | PDF | N/A | Laser speckle imaging of hepatic microcirculation | | 温度对早期胚胎细胞周期影响的机制起源 | Rombouts, J. | PDF | N/A | Mechanistic origins of temperature scaling in the early embryonic cell cycle | | 以下是这段文字的中文翻译：

儿童阅读障碍中的非典型视觉选择性注意：来自N2pc和PD的证据

翻译说明： - Atypical：非典型的，指与正常情况不同。 - Visual Selective Attention：视觉选择性注意，指在视觉信息中选择性地关注某些刺激而忽略其他刺激的能力。 - Dyslexia：阅读障碍，一种学习障碍，主要表现为阅读困难。 - Evidence from N2pc and PD：来自N2pc和PD的证据。N2pc和PD是脑电图（EEG）中的两个成分，分别与选择性注意和干扰抑制相关。

按性别划分的冈比亚按蚊胚胎发育过程中的转录组动态

翻译说明： - "Sex-specific" 翻译为“按性别划分的”，表示研究关注的是性别差异。 - "transcriptome dynamics" 翻译为“转录组动态”，指的是基因表达的变化过程。 - "Anopheles gambiae" 是“冈比亚按蚊”，一种传播疟疾的蚊子。 - "during embryonic development" 翻译为“胚胎发育过程中”，表示研究的时间范围。

分子对嗜铬粒蛋白B的需求：长期以来寻找的调节分泌的阴离子分流器

翻译解释： - "Molecular requirements" 翻译为 "分子需求" 或 "分子要求"。 - "chromogranin B" 是专业术语，直接保留英文名称 "嗜铬粒蛋白B"。 - "long-sought" 翻译为 "长期以来寻找的"。 - "anion shunter" 翻译为 "阴离子分流器"。 - "regulated secretion" 翻译为 "调节分泌"。

马达加斯加新型蝙蝠科布病毒的基因组特征：对病毒进化与人畜共患风险的启示

翻译说明： - "Genomic characterization" 译为“基因组特征”或“基因组表征”。 - "novel bat kobuviruses" 译为“新型蝙蝠科布病毒”，其中“novel”表示新发现的，“kobuviruses”是科布病毒（一种小RNA病毒）。 - "Madagascar" 译为“马达加斯加”，是非洲东南部的一个岛国。 - "implications for" 译为“对……的启示”或“对……的意义”。 - "viral evolution" 译为“病毒进化”。 - "zoonotic risk" 译为“人畜共患风险”，指病毒从动物传播给人类的潜在风险。

BioRxiv 2024-12-23 Papers

标题	作者	PDF链接	代码仓库	Title
深度学习揭示了细胞如何在类似组织的复杂环境中进行牵引、弯曲和导航。	Padhi, A.	PDF	N/A	Deep Learning Reveals How Cells Pull, Buckle, and Navigate Tissue-Like Environments
一个新的dynamin超家族成员调节布鲁氏锥虫线粒体膜分支	Morel, C. A.	PDF	N/A	A member of a new dynamin superfamily modulates mitochondrial membrane branching in Trypanosoma brucei
在一种海洋蜗牛中，在物种形成连续体的两个不同点上，平行生态型之间的表型差异和基因组结构	Raffini, F.	PDF	N/A	Phenotypic divergence and genomic architecture between parallel ecotypes at two different points on the speciation continuum in a marine snail
CDK8/19抑制剂减轻了BCR-ABL拮抗剂引起的G1期阻滞，并加速了慢性髓性白血病细胞的死亡。	Khamidullina, A. I.	PDF	N/A	CDK8/19 Inhibition Attenuates G1 Arrest Induced by BCR-ABL Antagonists and Accelerates Death of Chronic Myelogenous Leukemia Cells
通过具有引流静脉抑制的依赖层级的fMRI技术，在3T磁共振成像系统下实现全脑范围内特定层级的功能连接映射。	Chang, W.-T.	PDF	N/A	Enabling brain-wide mapping of layer-specific functional connectivity at 3T via layer-dependent fMRI with draining-vein suppression
人类肺组织中SARS-CoV-2感染消退的免疫特征	Kenney, D. J.	PDF	N/A	Immune Signatures of SARS-CoV-2 Infection Resolution in Human Lung Tissues
白喉素介导的呼吸氧化酶灵活性控制结核分枝杆菌的毒力	Buglino, J.	PDF	N/A	Chalkophore mediated respiratory oxidase flexibility controls M. tuberculosis virulence
嗜睡症T细胞的多组学分析：与T细胞增殖相关的solo-WCGW基序的全局低甲基化	Shimada, M.	PDF	N/A	Multiomics analysis of narcolepsy T cells: global hypomethylation in solo-WCGW motif linked to T cell proliferation
极小的背景噪音有助于神经语音追踪：随机共振的证据	Herrmann, B.	PDF	N/A	Minimal background noise enhances neural speech tracking: Evidence of stochastic resonance
青春期遭受同伴欺凌会改变基因表达和细胞因子特征，影响向成年期的过渡。	Heumann, J.	PDF	N/A	Peer victimization in adolescence alters gene expression and cytokine profiles during transition to adulthood
特定的前浆细胞状态和暗区-髓质界面处的局部增殖特征了淋巴结生发中心来源的浆细胞分化。	Binet, L.	PDF	N/A	Specific pre-plasma cell states and local proliferation at the dark zone - medulla interface characterize germinal center-derived plasma cell differentiation in lymph node
果蝇翅膀上性选择的目标	De Lisle, S. P.	PDF	N/A	Targets of sexual selection on the Drosophila wing
不对称基因流动维持了海洋无脊椎动物的分布边缘。	Hancock, Z. B.	PDF	N/A	Asymmetric gene flow maintains range edges in a marine invertebrate
对微生物物种树重建的系统发育基因组学方法进行系统评估	Weiner, S.	PDF	N/A	A systematic assessment of phylogenomic approaches for microbial species tree reconstruction
撤回：涉及EDN3的两个不同的结构变异导致鸡的色素沉着过度	Ma, C.	PDF	N/A	WITHDRAWN: Two distinct structural variants involving EDN3 cause hyperpigmentation in chicken
在ADAMTS13缺乏的情况下，微血栓的形成通过黏膜和内皮功能障碍加剧了溃疡性结肠炎。	Tatsuta, K.	PDF	N/A	Microthrombi-growth in ADAMTS13 deficiency exacerbated ulcerative colitis via mucosal and endothelial dysfunction
恢复阿尔茨海默病中的振荡动力学：一种关于血清素类迷幻药物效应的层级全脑模型	Gendra, J. C.	PDF	N/A	Restoring Oscillatory Dynamics in Alzheimer's Disease: A Laminar Whole-Brain Model of Serotonergic Psychedelic Effects
卡西尼：用于RNA和蛋白质原位分析的简化和可扩展方法	Lapique, N.	PDF	N/A	Cassini: Streamlined and Scalable Method for in situ profiling of RNA and Protein
使用单细胞qRT-PCR对成年小鼠心脏基质细胞进行的转录组分析	Alonaizan, R.	PDF	N/A	Transcriptomic analysis of adult mouse cardiac stromal cells using single-cell qRT-PCR
病原体在面对先天免疫记忆时的实验进化增加了毒力的变异	Korsa, A.	PDF	N/A	Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence
通过大规模分析天然配对的人类抗体序列和结构数据，揭示了保守的重/轻链接触和胚系偏好。	Dudzic, P.	PDF	N/A	Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data.
多组学图谱揭示了细胞毒性表型和与活性氧相关的代谢静止作为CTL耐受的HIV感染CD4+ T细胞的关键特征。	Herrera, A.	PDF	N/A	Multi-Omic Atlas reveals cytotoxic phenotype and ROS-linked metabolic quiescence as key features of CTL-resistant HIV-infected CD4+ T-cells
在社区范围内多次治疗后蛔虫的分子流行病学：谁感染了谁？	Landeryou, T.	PDF	N/A	Molecular epidemiology of Ascaris lumbricoides following multiple rounds of community-wide treatment: who infects whom?
与截短型肌联蛋白（ttn.2）变异相关的心肌和骨骼肌功能障碍的部位依赖性差异	Santiago, C. F.	PDF	N/A	Location-Dependent Differences in Cardiac and Skeletal Muscle Dysfunction Associated With Truncating Titin (ttn.2) Variants
一种进化上保守的色氨酸笼促进了hnRNPR样蛋白家族中延伸的RNA识别基序的折叠。	Atsrim, E. S.	PDF	N/A	An evolutionarily conserved tryptophan cage promotes folding of the extended RNA recognition motif in the hnRNPR-like protein family
抗有丝分裂化疗促进了三阴性乳腺癌中肿瘤NF-kB分泌表型和免疫抑制性CXCR2+中性粒细胞的趋化作用。	Chocteau, F.	PDF	N/A	Antimitotic chemotherapy promotes tumor NF-kB secretory phenotype and immunosuppressive CXCR2+ neutrophils chemotaxis in triple-negative breast cancers
利用源自患者的混合搭配前脑组合体识别人类精神分裂症中的神经元-胶质信号反馈	Kim, E.	PDF	N/A	Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids
感觉预期在运动回路中塑造神经群体动力学	Michaels, J. A.	PDF	N/A	Sensory expectations shape neural population dynamics in motor circuits
用于体内多重成像的红移GRAB乙酰胆碱传感器	Xie, S.	PDF	N/A	Red-shifted GRAB acetylcholine sensors for multiplex imaging in vivo
线粒体分裂与融合对神经元健康及痴呆发病率的影响	Davies, A. M.	PDF	N/A	Impact of mitochondrial fission and fusion onneuronal health and incidence of dementia
非本地植物对本地植物的支配优势随着全球变化因素数量的增加而增强。	Shi, X.	PDF	N/A	The dominance of non-native plants over native plants increases with the number of global change factors
墨西哥脂鲤（Astyanax mexicanus）表层鱼和洞穴鱼性腺中性调控基因的差异表达	Webster, K. A.	PDF	N/A	Differential expression of sex regulatory genes in gonads of Astyanax mexicanus surface fish and cavefish
蜜蜂社交性个体差异的分子分析	Traniello, I. M.	PDF	N/A	Molecular analyses of individual variation in honey bee sociability
化学蛋白质组学鉴定单酰甘油脂类的蛋白质配体	Shanbhag, K.	PDF	N/A	Chemical Proteomics Identifies Protein Ligands for Monoacylglycerol Lipids
HYDRA：用于高通量药物测试的机器人自动化水凝胶分配系统	Torchia, E.	PDF	N/A	HYDRA: HYdrogel Dispensing with Robotic Automation for high throughput drug testing
卡巴苏拉库迪尼尔·乔尔纳姆（Kabasura Kudineer Choornam），一种多草药制剂，能够调节人体巨噬细胞的极化及吞噬功能。	Korkmaz, A.	PDF	N/A	Kabasura Kudineer Choornam, a medicinal polyherbal formulation, modulates human macrophage polarization and phagocytic function
基质晶格的结构成熟并非HIV-1颗粒感染性所必需的。	Chen, L.	PDF	N/A	Structural maturation of the matrix lattice is not required for HIV-1 particle infectivity
一种受信号传导启发的合成工具包，用于高效生产酪氨酸磷酸化蛋白质	Ryan, M. M.	PDF	N/A	A signaling inspired synthetic toolkit for efficient production of tyrosine phosphorylated proteins
限制Ku向内转运封顶端粒末端	Mattarocci, S.	PDF	N/A	Restriction on Ku's Inward Translocation Caps Telomere Ends
环状肌动蛋白-肌球蛋白束驱动内皮细胞变形，以收缩血管。	Chen, Y.	PDF	N/A	Circumferential actomyosin bundles drive endothelial cell deformations to constrict blood vessels
Fbxo42促进Ataxin-2颗粒的降解，从而触发终末Xbp1信号传导。	Santos, C. C.	PDF	N/A	Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling
探索mScarlet在开发用于钙成像的红光寿命传感器中的应用	van der Linden, F. H.	PDF	N/A	Exploration of mScarlet for development of a red lifetime sensor for calcium imaging
条纹獴能够辨别陌生同种个体之间的亲缘关系和主要组织相容性复合体（MHC）的多样性。	Schubert, N.	PDF	N/A	Banded mongooses discriminate relatedness and MHC diversity in unfamiliar conspecifics
自然界中的非典型细胞色素P450酶	Nguy, A. K. L.	PDF	N/A	Non-Canonical Cytochrome P450 Enzymes in Nature
裸露DNA发夹结构中的A-T Hoogsteen碱基对：一种蛋白质识别的构象	Guseva, S.	PDF	N/A	An A-T Hoogsteen base pair in a naked DNA hairpin motif: A Protein-Recognized Conformation
癌症组蛋白突变影响结合和DNA修复过程，导致突变率增加	Espiritu, D.	PDF	N/A	Cancer Histone Mutations Impact Binding and DNA Repair Processes, Leading to Increased Mutagenesis
阿根廷B族链球菌的基因组特征：对噬菌体多样性、毒力因子及抗生素抗性基因的洞察	Kovacec, V.	PDF	N/A	Genomic Characterisation of Group B Streptococcus from Argentina: Insights into Prophage Diversity, Virulence Factors and Antibiotic Resistance Genes
人类参考图谱知识图谱的构建、部署与关联开放数据应用	Bueckle, A. D.	PDF	N/A	Construction, Deployment, and Usage of the Human Reference Atlas Knowledge Graph for Linked Open Data
BenchXAI：在多模态生物医学数据上对事后可解释AI方法的综合基准测试	Metsch, J.	PDF	N/A	BenchXAI: Comprehensive Benchmarking of Post-hoc Explainable AI Methods on Multi-Modal Biomedical Data
ScPectral: 通过光谱聚类转录网络的超图表示来识别发育路径	BERSENEV, D.	PDF	N/A	ScPectral: Spectrally Clustering HypergraphRepresentations of Transcription Networks to Identify Developmental Pathways
KIDINS220和肌醇焦磷酸对人类磷酸盐出口蛋白XPR1的协同激活	Zuo, P.	PDF	N/A	Synergistic activation of the human phosphate exporter XPR1 by KIDINS220 and inositol pyrophosphate
FAK信号在Rac1驱动的黑色素瘤细胞对MAPK通路抑制的抗性中起着关键作用。	Riordan, J. D.	PDF	N/A	A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition
用于在小鼠睾丸生殖细胞中通过碱性彗星试验评估体内DNA损伤水平的协议	Olsen, A.-K.	PDF	N/A	Protocol for assessing DNA damage levels in vivo in rodent testicular germ cells in the Alkaline Comet Assay
胆汁酸与重度抑郁症患者执行控制网络和默认模式网络连接性的关联	Dunlop, B.	PDF	N/A	Association of Bile Acids with Connectivity of Executive Control and Default Mode Networks in Patients with Major Depression
利用设计的远红光多巴胺传感器实现活体内动态神经化学网络的多重成像	Zheng, Y.	PDF	N/A	In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors
FGF21类似物PF-05231023对伏隔核中酒精摄入量和神经元活动的影响	Cooley, B. J.	PDF	N/A	FGF21 Analogue PF-05231023 on Alcohol Consumption and Neuronal Activity in the Nucleus Accumbens
穿越迷宫：识别从fMRI脑模式进行注意力状态分类中的潜在陷阱	Bressler, R. A.	PDF	N/A	Navigating the Maze: Identifying Potential Pitfalls in Attention State Classification from fMRI Brain Patterns
加拿大盾地双温湖中细胞相关病毒群落的组成及其功能潜力	Collis, C. C.	PDF	N/A	Cell-associated viral community composition and its functional potential in a dimictic lake on the Canadian Shield
空间有序的合子基因组激活实现了胚胎质量控制。	Qian, W.	PDF	N/A	Spatially ordered zygotic genome activation fulfills embryo quality control
澳大利亚的黑狐蝠携带新型伯氏疏螺旋体谱系，这些谱系与可传给人的分支相邻。	Verrett, T. B.	PDF	N/A	Black flying foxes in Australia harbor novel Borrelia lineages adjacent to zoonotic clades
RNA-SeqEZPZ：一个点击式管道，用于综合转录组学分析与交互式可视化	Taslim, C. R.	PDF	N/A	RNA-SeqEZPZ: A Point-and-Click Pipeline for Comprehensive Transcriptomics Analysis with Interactive Visualizations
用于生产取代的2-喹诺酮和（硫代）香豆素的生物催化平台	Sokolova, N.	PDF	N/A	A biocatalytic platform for the production of substituted 2-quinolones and (thio)coumarins
StripePy：快速且稳健的建筑条纹表征	Raffo, A.	PDF	N/A	StripePy: fast and robust characterization of architectural stripes
在类原肠胚中，形态发生和转录程序在时间上的解耦依赖于尺寸	Bennabi, I.	PDF	N/A	Size-dependent temporal decoupling of morphogenesis and transcriptional programs in gastruloids
稀疏神经网络能够实现低功耗、可植入的神经接口。	Costello, J. T.	PDF	N/A	Sparse neural networks enable low-power, implantable neural interfaces
人类肺部通用单细胞转录组图谱解码多种肺部疾病	Wu, F.	PDF	N/A	A universal single-cell transcriptomics atlas of human lung decodes multiple pulmonary diseases
开发一种新型外周作用的α2A-肾上腺素受体拮抗剂用于抗糖尿病治疗	Hong, F.	PDF	N/A	Development of a novel peripherally acting alpha2A-adrenergic receptor antagonist for anti-diabetic
一种自由可访问、可调整的中空纤维装置，用于再现一级吸收：以利奈唑胺脑脊液药代动力学数据为例说明	Prebonnaud, N.	PDF	N/A	A freely accessible, adaptable hollow-fiber setup to reproduce first-order absorption: illustration with linezolid cerebrospinal fluid pharmacokinetic data
急性缺血期间，复极化-舒张耦联的紊乱允许收缩期机械-心律失常的发生。	Cameron, B. A.	PDF	N/A	Disturbed repolarisation-relaxation coupling during acute ischaemia permits systolic mechano-arrhythmogenesis.
肿瘤相关巨噬细胞增强肿瘤神经支配及脊髓修复	Dolci, S.	PDF	N/A	Tumor-associated macrophages enhance tumor innervation and spinal cord repair
ampD突变导致Chromobacterium violaceum中超量产生AmpC和CphA β-内酰胺酶，并对其β-内酰胺类抗生素产生高耐药性。	Laranjeiro, L. G.	PDF	N/A	Mutations in ampD cause hyperproduction of AmpC and CphA beta-lactamases and high resistance to beta-lactam antibiotics in Chromobacterium violaceum
病原性减弱型鼠衣原体突变株在生殖道中的传染性	Li, C.	PDF	N/A	Infectivity of a pathogenicity-attenuated Chlamydia muridarum mutant in the genital tract
一种分泌的蠕虫微小RNA抑制了胃肠道细胞分化，而这种分化是先天免疫所必需的。	Perez, M. G.	PDF	N/A	A secreted helminth microRNA suppresses gastrointestinal cell differentiation required for innate immunity
单细胞和空间基因组学健康与疾病中人类皮肤成纤维细胞图谱	Steele, L.	PDF	N/A	A single cell and spatial genomics atlas of human skin fibroblasts in health and disease
在静止期阻滞期间，动态的p21依赖性通过一种快速p21耗竭系统得以揭示	Liang, H.	PDF	N/A	Dynamic p21-dependency during quiescence arrest unveiled by a rapid p21 depletion system
使用新型荧光标记的长链脂肪酸类似物检测白细胞中的甘油三酯代谢	Hara, Y.	PDF	N/A	Detection of triglyceride metabolism in white blood cells using a novel fluorescently labeled long chain fatty acid analogue
BMI1介导的异染色质化通过抑制G四链体DNA的形成，在复制过程中维持基因组的稳定性。	Hanna, R.	PDF	N/A	BMI1-mediated heterochromatinization represses G-quadruplex DNA formation to maintain genomic stability during replication
DMD-3对秀丽隐杆线虫雄性尾部顶端形态发生的转录调控	Fernandez, P.	PDF	N/A	Transcriptional control of C. elegans male tail tip morphogenesis by DMD-3
赤道几内亚比奥科岛上的疟疾寄生虫恶性疟原虫定期输入，阻碍了该岛疟疾的消除。	Stabler, T. C.	PDF	N/A	Regular Plasmodium falciparum importation onto Bioko Island, Equatorial Guinea, hampers malaria elimination from the island
近端小管特异性缺失二肽基肽酶4对血压、肾钠处理及NHE3磷酸化的影响	Martins, F. L.	PDF	N/A	Impact of Proximal Tubule-Specific Deletion of Dipeptidyl Peptidase 4 on Blood Pressure, Renal Sodium Handling, and NHE3 Phosphorylation
结肠是一个胰腺外的胰高血糖素来源：在胰切除术小鼠模型中的证明	Jarry, A.-C.	PDF	N/A	The colon is an extra-pancreatic source of glucagon: demonstration in a mouse model of pancreatectomy
益生菌酿酒酵母（Saccharomyces boulardii）中用于肠道脱落酸生产的多步途径工程	Van Gaever, F.	PDF	N/A	Multi-Step Pathway Engineering in Probiotic Saccharomyces boulardii for Abscisic Acid Production in the Gut
多巴胺能调节对纹状体中型多棘神经元亚型状态转换的影响——一项计算研究	Anisetty, N.	PDF	N/A	Impact of dopaminergic modulation on the state transitions of striatal medium spiny neuron sub-types - a computational study
性失败通过多巴胺能信号传导降低雄性果蝇对甜味的感知	Wang, G.	PDF	N/A	Sexual Failure Decreases Sweet Taste Perception in Male Drosophila via Dopaminergic Signaling
作为基本逻辑运算符的工程生物神经网络	Küchler, J.	PDF	N/A	Engineered biological neural networks as basic logic operators
使用大规模机器学习预测低级别胶质瘤患者对替莫唑胺的反应	Du, H.	PDF	N/A	Predicting temozolomide response in low-grade glioma patients with large-scale machine learning
转录组学揭示了人类细胞系中经典和非经典热休克诱导通路	Reinschmidt, A.	PDF	N/A	Transcriptomics Unveil Canonical and Non-Canonical Heat Shock-Induced Pathways in Human Cell Lines
MEANtools：面向代谢物预测和生物合成途径预测的多组学整合工具	Singh, K. S.	PDF	N/A	MEANtools: multi-omics integration towards metabolite anticipation and biosynthetic pathway prediction
形状约束的、含变点的加性模型用于时间序列组学数据的cpam	Yates, L. A.	PDF	N/A	Shape-constrained, changepoint additive models for time series omics data with cpam
IFNα 抑制 JAK2V617F 驱动的恶性血管生成和内皮细胞向间充质细胞的转变，基于三维 iPSC 的骨髓微环境模型	Caduc, M. J.	PDF	N/A	IFNα Inhibits JAK2V617F-Driven Neoplastic Vasculogenesis and Endothelial-to-Mesenchymal Transition in a 3D iPSC-Based Bone Marrow Niche Model
具有不同轴突连接的皮层投射神经元采用具有不同蛋白质组成的核糖体复合物。	Tran, T. P.	PDF	N/A	Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions
具有不同轴突连接的皮层投射神经元使用具有不同蛋白质组成的核糖体复合物。	Tran, T. P.	PDF	N/A	Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions
促进聚集的序列而非磷酸化对于Tau蛋白在果蝇中介导的毒性至关重要。	Cooper, A.	PDF	N/A	Aggregation promoting sequences rather than phosphorylation are essential for Tau-mediated toxicity in Drosophila
平衡术：自发言语中连贯性与创造性之间的神经权衡	Patel, T.	PDF	N/A	Balancing Act: A Neural Trade-Off Between Coherence and Creativity in Spontaneous Speech
甲氧西林耐药金黄色葡萄球菌对二线/末线抗生素体外耐药选择特征研究	Prasetyoputri, A.	PDF	N/A	Characterisation of in vitro resistance selection against second-/last-line antibiotics in methicillin-resistant Staphylococcus aureus
SORBS1的替代剪接影响肌强直性营养不良1型中的神经肌肉接头形成和稳定性	Hermitte, C.	PDF	N/A	Alternative splicing of SORBS1 affects neuromuscular junction formation and stability in myotonic dystrophy type 1
分裂酵母中不同细胞位点的内吞斑动态受到差异性调控	Campbell, B. F.	PDF	N/A	Endocytic Patch Dynamics are Differentially Regulated at Distinct Cell Sites in Fission Yeast
小鼠原肠胚形成的空间时间调控逻辑	Yang, X.	PDF	N/A	Spatiotemporal Regulatory Logics of Mouse Gastrulation
地理分布对中美洲脂鲤鱼类单殖吸虫寄生虫（扁形动物门）多样化的预测作用强于宿主亲缘关系。	Alda, F.	PDF	N/A	Geography is a stronger predictor of diversification of monogenean parasites (Platyhelminthes) than host relatedness in characid fishes of Middle America
一种针对地中海实蝇的自限性无菌昆虫技术替代方案	Davydova, S.	PDF	N/A	A self-limiting Sterile Insect Technique alternative for Ceratitis capitata
色氨酸代谢物图谱揭示了器官、年龄和性别特异性的变异	Perez-Castro, L.	PDF	N/A	Tryptophan metabolite atlas uncovers organ, age, and sex-specific variations
人类疾病中的蛋白质稳态特征	Lim, C. M.	PDF	N/A	Proteostasis Signatures in Human Diseases
CORTADO: 用于细胞类型特异性标记基因发现的爬山优化	Lodi, M.	PDF	N/A	CORTADO: Hill Climbing Optimization for Cell-Type SpecificMarker Gene Discovery
FAIRSCAPE：一个不断发展的生物医学研究AI准备框架	Al Manir, S.	PDF	N/A	FAIRSCAPE: An Evolving AI-readiness Framework for Biomedical Research
通过精确预测三维DNA力学，探索不同真核生物基因组中的机械选择	Park, J.	PDF	N/A	Probing mechanical selection in diverse eukaryotic genomes through accurate prediction of 3D DNA mechanics
功能性不对称下的步态适应：探究步宽、步长和质心在侧向稳定性中的作用	Bacek, T.	PDF	N/A	Gait Adaptations Under Functional Asymmetry: Exploring the Role of Step Width, Step Length, and CoM in Lateral Stability
测试纤维蛋白原样1在代谢功能障碍相关脂肪性肝病和肝细胞癌发病机制中的贡献	Personnaz, J.	PDF	N/A	Testing the contribution of fibrinogen like 1 to the pathogenesis of metabolic dysfunction associated steatotic liver disease and hepatocellular carcinoma
职业苯暴露引起的小鼠代谢失调的综合多组学分析	Scofield, S.	PDF	N/A	Integrative multiomics analysis of metabolic dysregulation induced by occupational benzene exposure in mice
基于温度的MHC I类多聚体肽交换用于人类HLA-A、B和C	Pothast, C. R.	PDF	N/A	Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C
PfATP2是恶性疟原虫表面的一种关键翻转酶，影响寄生虫对疟疾药物的敏感性。	Qiu, D.	PDF	N/A	PfATP2 is an essential flippase on the Plasmodium falciparum surface that influences parasite sensitivity to antiplasmodial compounds
在年轻物种群中的渐渗与分化	Satokangas, I.	PDF	N/A	Introgression and divergence in a young species group
通过单粒子追踪技术揭示活细胞表面上的DNA折纸相互作用动力学	Van Zundert, I.	PDF	N/A	Unveiling DNA Origami Interaction Dynamics on Living Cell Surfaces by Single Particle Tracking
单细胞扰动响应预测模型的系统性比较	Li, L.	PDF	N/A	A Systematic Comparison of Single-Cell Perturbation Response Prediction Models
在情节记忆期间的网络隔离显示出从7岁到82岁与记忆表现之间的年龄不变关系	Grydeland, H.	PDF	N/A	Network Segregation During Episodic Memory Shows Age-Invariant Relations with Memory Performance From 7 to 82 Years
一个简单的体外膀胱感染模型允许研究尿路感染中的宿主-病原体相互作用。	Koehn, R.-M.	PDF	N/A	A simple ex vivo bladder infection model permits study of host-pathogen interactions in UTI
台湾灵芝多糖通过下调髓源性抑制细胞和肿瘤相关巨噬细胞的分化来增强抗肿瘤免疫反应。	Yang, J.-Y.	PDF	N/A	Ganoderma formosanum polysaccharides enhance antitumor immune responses by downregulating the differentiation of myeloid-derived suppressor cells and tumor-associated macrophages
一种噬菌体编码的反防御机制抑制了NAD降解的抗噬菌体防御系统。	Loyo, C.	PDF	N/A	A phage-encoded counter-defense inhibits an NAD-degrading anti-phage defense system
非洲和亚洲对青蒿素具有不同敏感性的恶性疟原虫分离株的配子体产生和传播适应性	Proellochs, N. I.	PDF	N/A	Gametocyte production and transmission fitness of African and Asian Plasmodium falciparum isolates with differential susceptibility to artemisinins
植物先锋因子LFY在脊椎动物中利用跨界的染色质重塑机制。	Ribeiro, F.	PDF	N/A	The plant pioneer factor LFY uses trans-kingdom chromatin remodeling mechanisms in vertebrates
纤维化样胶原基质作为创新的3D体外模型，用于研究病理性细胞外基质对肌肉营养不良中肌肉再生的影响。	Camman, M.	PDF	N/A	Fibrotic-like collagen matrices as innovative 3D in vitro models for investigating the impact of pathological ECM on muscle regeneration in muscular dystrophies
MAPK15 对代谢功能障碍相关脂肪性肝病的发生具有保护作用	Inzalaco, G.	PDF	N/A	MAPK15 Protects Against The Development Of Metabolic Dysfunction-Associated Steatotic Liver Disease
Methyl-CODEC技术实现了同时进行甲基化和双链测序。	Liu, R.	PDF	N/A	Methyl-CODEC enables simultaneous methylation and duplex sequencing
MacqD - 一种基于深度学习的模型，用于自动检测社会饲养实验室猕猴	Moat, G. J.	PDF	N/A	MacqD - A Deep Learning-based Model for Automatic Detection of Socially-housed Laboratory Macaques
自适应光学滚动狭缝眼底镜：在多模态视网膜成像仪中结合细胞级分辨率、高速和大视场	Krafft, L.	PDF	N/A	Adaptive Optics Rolling Slit Ophthalmoscope: Combining cellular-resolution, high-speed and large field-of-view in a multimodal retinal imager
用于无偏建模细菌菌落生长的流体衍生晶格	Verhoef, B.	PDF	N/A	Fluid-Derived Lattices for Unbiased Modeling of Bacterial Colony Growth
APR-246 和 COTI-2 通过 ROS 诱导的 DNA 损伤和铁死亡增加 p53 突变型 HPV 阴性头颈部鳞状细胞癌的化学放疗敏感性	de Bakker, T.	PDF	N/A	APR-246 & COTI-2 increase chemoradiotherapy sensitivity via ROS-induced DNA damage and ferroptosis in p53 mutant HPV negative head and neck squamous cell carcinoma
节能代谢开关是极端嗜盐红微藻在极高镍水平下生存的基础。	Santaeufemia, S.	PDF	N/A	The energy-saving metabolic switch underlies survival of extremophilic red microalgae in extremely high nickel levels
基因网络结构、突变和选择共同推动了发育模式的可进化性和可预测性。	Booth, H.	PDF	N/A	Gene network architecture, mutation and selection collectively drive developmental pattern evolvability and predictability
研究乙二醛酶1在可卡因和羟考酮使用障碍中的治疗靶点作用	Alcantara, E.	PDF	N/A	Investigating the Role of Glyoxalase 1 as a Therapeutic Target for Cocaine and Oxycodone Use Disorder
Grin2a消融显著重塑了内侧前额叶皮层中PV+和SST+中间神经元的电路，从而放大了伽马振荡。	Hosseini, H.	PDF	N/A	Grin2a Ablation Distinctly Reshapes PV+ and SST+ Interneuron circuits in the Medial Prefrontal Cortex to Amplify Gamma Oscillations
皮层中新奇性的关键性扩展	Ribeiro, T. L.	PDF	N/A	Critical Scaling of Novelty in the Cortex
YAP调节骨折修复中的骨膜扩张	Nijsure, M. P.	PDF	N/A	YAP regulates periosteal expansion in fracture repair
从计算角度重建癌症进展风险演变	Cao, K.	PDF	N/A	Computationally reconstructing the evolution of cancer progression risk
在哥伦比亚弗洛伦西亚，卡克塔地区，基于干饲料、活饲料和湿饲料的三种饮食对盘丽鱼（Symphysodon p.）在受控条件下的最佳生长进行了评估。	Navarro-Morales, A.	PDF	N/A	Evaluation of Three Diets Based on Dry, Live, and Wet Feeds for Optimal Growth of Discus Fish (Symphysodon p.) Under Controlled Conditions in Florencia, Caqueta, Colombia
在抗原暴露后早期出现的异质性活化B细胞群的特征，该群细胞在长寿命记忆B细胞形成之前出现。	Fernandez Blanco, L.	PDF	N/A	Characterization of a heterogenous activated B cell compartment arising early after antigen exposure preceding long-lived memory B cell formation
Tecovirimat对猴痘病毒分支1a、1b、2a和2b的抗病毒活性	Postal, J.	PDF	N/A	Antiviral activity of Tecovirimat against Mpox virus clades 1a, 1b, 2a and 2b
LEF1-AS1在持续性新冠症状患者外周血中的失调	Made, A.	PDF	N/A	LEF1-AS1 deregulation in the peripheral blood of patients with persistent post-COVID symptoms
基因表达受到相互作用的核苷酸供应和mRNA组成需求的全球性调控：这一机制被多种疾病状态和药物治疗所破坏。	Pickard, B. S.	PDF	N/A	Gene expression is globally regulated by interacting nucleobase supply and mRNA composition demand: a mechanism disrupted by multiple disease states and drug treatments
一种基于甲基化的年龄预测方法的综合评估	Wang, H.	PDF	N/A	A Comprehensive Assessment of Methylation-Based Age Prediction Methods
通过多轮肽结合实验结合自由能回归，为SH2结构域构建精确的序列到亲和力模型	Gagoski, D.	PDF	N/A	Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression
运动前β活动的出现与稳定的感知运动预测相结合，以促进运动调整	Bracco, M.	PDF	N/A	Emergence of Pre-movement Beta Activity with Stable Sensorimotor Predictions to Facilitate Motor Adjustments
运动过程中大脑灌注及星形胶质细胞和神经元的代谢反应	Tiaglik, A.	PDF	N/A	Cerebral perfusion and metabolic response of astrocytes and neurons during locomotion
噪声中语音的听觉脑干反应反映了选择性注意、理解能力以及主观听力努力程度。	Mankel, K.	PDF	N/A	Auditory brainstem responses to speech-in-noise reflect selective attention, comprehension, and subjective listening effort
WASp介导的肌动蛋白聚合作用限制了巨噬细胞中核膜破裂和炎症的发生。	Amadio, R.	PDF	N/A	Actin polymerization by WASp limits nuclear envelope rupture and inflammation in macrophages
从尼日利亚伊巴丹市家庭水源分离出的埃希氏大肠杆菌中抗菌药物耐药性的遗传基础	Akintayo, I. J.	PDF	N/A	Genetic basis for antimicrobial resistance in Escherichia coli isolated from household water in municipal Ibadan, Nigeria
细菌周质捕食的定量蛋白质组揭示了捕食对象损伤蛋白酶	Lai, T. F.	PDF	N/A	Quantitative proteome of bacterial periplasmic predation reveals a prey damaging protease
细胞质过氧化物酶Tsa1影响葡萄酒酵母的醋酸代谢和pH稳态	Garrigos, V.	PDF	N/A	Cytosolic peroxiredoxin Tsa1 influences acetic acid metabolism and pH homeostasis in wine yeasts
通过海洋硅藻Phaeodactylum tricornutum中的RITMO1时钟蛋白对关键生理过程的昼夜节律调控	Manzotti, A.	PDF	N/A	Circadian regulation of key physiological processes by the RITMO1 clock protein in the marine diatom Phaeodactylum tricornutum
血管紧张素II在近球小体细胞簇内引发强烈的钙离子振荡，这种协调的振荡作用抑制了肾素的分泌。	Yamaguchi, H.	PDF	N/A	Angiotensin II elicits robust calcium oscillations coordinated within juxtaglomerular cell clusters to suppress renin secretion.
LBR和LAP2介导异染色质与核膜的结合，以维持基因组的稳态。	Lewis, R.	PDF	N/A	LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis
TRF1和TRF2在端粒处形成不同的shelterin亚复合物。	Janovic, T.	PDF	N/A	TRF1 and TRF2 form distinct shelterin subcomplexes at telomeres
eDNA通过整合生物能量学和颗粒物质量平衡，提供了对生物丰度的准确和精确估计。	Beaulieu, J.	PDF	N/A	eDNA provides accurate and precise estimates of abundance by integrating bioenergetics and particle mass-balance
在酶进化过程中，残基间结构分歧的变化	Echave, J.	PDF	N/A	On the variation of structural divergence among residues in enzyme evolution
全转录组分析显示，感染牛白血病病毒（BLV）的牛中，高前病毒载量牛的免疫反应基因呈现下调趋势。	Petersen, M. I.	PDF	N/A	Whole-transcriptome analysis of BLV-infected cows reveals downregulation of immune response genes in high proviral loads cows.
性特异性鱼类重组景观将重组与染色体组型进化联系起来	Kivioja, T.	PDF	N/A	Sex-specific fish recombination landscapes link recombination and karyotype evolution
对真菌高还原性聚酮合酶缩合区进行生化剖析揭示了酰基选择的基础。	Foran, M. E.	PDF	N/A	Biochemical dissection of a fungal highly reducing polyketide synthase condensing region reveals basis for acyl group selection.
自行动手从头开始抗体测序工作流程，实现可变区域完全准确性	He, M.-T.	PDF	N/A	Do-it-yourself de novo antibody sequencing workflow that achieves complete accuracy of the variable regions
SHP2通过双酪氨酸磷酸化的Gab1激活的机制	Machner, L.	PDF	N/A	Mechanism of SHP2 activation by bis-Tyr-phosphorylated Gab1
用于细胞成像中精准表型分析的混杂因素感知基础模型	Papanastasiou, G.	PDF	N/A	Confounder-aware foundation modeling for accurate phenotype profiling in cell imaging
全基因组鉴定、表征及黄瓜（Cucumis sativus L）CsC3H基因家族在多种非生物胁迫下的表达分析	Uddin, S.	PDF	N/A	Genome-wide identification, characterization and expression analysis of CsC3H gene family in cucumber (Cucumis sativus L) under various abiotic stresses
YDS-Ternoplex：超越AlphaFold 3型模型，用于分子胶介导的三元复合物预测	Che, X.	PDF	N/A	YDS-Ternoplex: Surpassing AlphaFold 3-Type Models for Molecular Glue-Mediated Ternary Complex Prediction
在实验室中展示用于关联低温生物成像的软X射线断层扫描技术，结合使用X射线和光学显微镜。	O'Connor, S.	PDF	N/A	Demonstrating Soft X-Ray Tomography in the lab for correlative cryogenic biological imaging using X-rays and light microscopy
Ephrin-A5和EphA7的刺激在体外对人横纹肌肉瘤具有抗增殖作用。	Cecchini, A.	PDF	N/A	Ephrin-A5 and EphA7 stimulation is anti-proliferative for human rhabdomyosarcoma in vitro
MITF、TFEB和TFE3的功能特化驱动了黑色素瘤中截然不同的适应性基因表达程序。	Dias, D.	PDF	N/A	Functional specialization of MITF, TFEB and TFE3 drives radically distinct adaptive gene expression programs in melanoma.
探索腺苷类似物用于软骨肉瘤治疗：体外和体内研究	Lente, M.	PDF	N/A	Exploring Adenosine Analogues for Chondrosarcoma Therapy: In Vitro and In Vivo Insights
探索高LET氧离子FLASH辐射在体外和体内靶向胰腺癌的应用	Karle, C.	PDF	N/A	Exploring High LET Oxygen-Ion FLASH Radiation for Targeting Pancreatic Cancer in Vitro and In Vivo
昼夜节律PERIOD蛋白塑造了哺乳动物的替代剪接景观。	Chikhaoui, L.	PDF	N/A	Circadian PERIOD proteins sculpt themammalian alternative splicing landscape
通过泛素-蛋白酶体系统直接调控孢子体向配子体的转变	Sivakumar, P.	PDF	N/A	Sporophyte Directed Gametogenesis via the Ubiquitin Proteasome System
模拟阿塔卡马地貌中土壤微生物群的新陈代谢潜能	Andreani-Gerard, C. M.	PDF	N/A	Modeling the emergent metabolic potential of soil microbiomes in Atacama landscapes
利用突触修剪的细胞模型鉴定能够穿透血脑屏障的小分子人小胶质细胞调节剂	McCrea, L. M.	PDF	N/A	Identifying brain-penetrant small molecule modulators of human microglia using a cellular model of synaptic pruning
使用深度生成模型进行大脑和行为的同步表征与预测建模：一个从监督到非监督的渐进式建模框架。	McVeigh, K.	PDF	N/A	Using deep generative models for simultaneous representational and predictive modeling of brain and behavior: A graded supervised-to-unsupervised modeling framework.
收集、检测和处理纵向光暴露数据中的非穿戴间隔	Guidolin, C.	PDF	N/A	Collecting, detecting and handling non-wear intervals in longitudinal light exposure data
用于控制外周视觉的中央凹作用	Zhang, T.	PDF	N/A	Foveal action for the control of extrafoveal vision
通过高吞吐量的光学生理学剖析谷氨酸能突触的功能异质性	Barlow, S. T.	PDF	N/A	Dissecting the functional heterogeneity of glutamatergic synapses with high-throughput optical physiology
放射状胶质祖细胞中细胞周期调节因子cyclin D1的细胞质表达，调控大脑皮层发育	PEDRAZA, N.	PDF	N/A	Cytoplasmic expression of the cell cycle regulator cyclin D1 in radial glial progenitor cells modulates brain cortex development
在呼吸道病毒感染后诱导的I型干扰素会损害肺部转移的起始。	Farias, A.	PDF	N/A	Type I interferons induced upon respiratory viral infection impair lung metastatic initiation
哺乳动物的ZAP和KHNYN独立地限制富含CpG的禽类病毒。	Becker, J. T.	PDF	N/A	Mammalian ZAP and KHNYN independently restrict CpG-enriched avian viruses
含有内含子的HIV-1 RNA的表达在髓系细胞中诱导NLRP1炎症小体激活	Jalloh, S.	PDF	N/A	Expression of Intron-containing HIV-1 RNA Induces NLRP1 Inflammasome Activation in Myeloid Cells
一种特殊的细菌II类内含子是一种高效的逆转录转座子。	Gomes, L.	PDF	N/A	A specialized bacterial group II intron is a highly efficient retrotransposon
BAX内有一个带门控的疏水通道，能够结合长链烯醛，从而增强其促凋亡功能。	Gelles, J. D.	PDF	N/A	A gated hydrophobic funnel within BAX binds long-chain alkenals to potentiate pro-apoptotic function
视紫红质组装核心的靶向递送对于小鼠视杆光感受器外节延伸是必需的。	Martinez-Marquez, J. Y.	PDF	N/A	Targeted delivery of rhodopsin's assembled core is required for outer segment extension in mouse rod photoreceptors
POLO激酶通过抑制蛋白磷酸酶1来促进纺锤体组装检验点，并防止非整倍体。	Moura, M.	PDF	N/A	POLO kinase inhibits Protein Phosphatase 1 to promote the Spindle Assembly Checkpoint and prevent aneuploidy
β整合素中的NPxY基序调控秀丽隐杆线虫的血清素反应和机械感受。	Bumm, J. H.	PDF	N/A	The NPxY motifs in the β integrin regulate serotonin response and mechanosensation in C. elegans
肿瘤源性胶质生成在果蝇中枢神经系统中维持了依赖去分化的肿瘤生长。	Alvarez-Ochoa, E.	PDF	N/A	Tumour-derived gliogenesis sustains dedifferentiation-dependent tumour growth in the Drosophila CNS
在无腔动物中，肌肉损伤诱导的神经营养素-ErbB信号传导能够动员干细胞，促进全身再生。	Stevens, B.	PDF	N/A	Injury-induced Neuregulin-ErbB signaling from muscle mobilizes stem cells for whole-body regeneration in Acoels
评估字符进化模型对从化石数据中进行系统发育和宏观进化推断的影响	Wright, D. F.	PDF	N/A	Assessing the impact of character evolution models on phylogenetic and macroevolutionary inferences from fossil data
从体细胞拷贝数谱中进行一致性整合与特征提取	Streck, A.	PDF	N/A	CNSistent integration and feature extraction from somatic copy number profiles
交配频率在偶发性多配雄性螨虫的个性表达中起着中介作用。	SCHAUSBERGER, P.	PDF	N/A	MATING FREQUENCY MEDIATES PERSONALITY EXPRESSION IN FACULTATIVELY POLYANDROUS MITES
点击连接：一种基于点击化学的细胞兼容性蛋白质交联方法	Amaral, B. C.	PDF	N/A	Click-linking: a cell-compatible protein crosslinking method based on click chemistry
Setdb1和Atf7IP形成了一个异源三聚体复合物，该复合物阻断了Setdb1的核输出。	Kariapper, L. S.	PDF	N/A	Setdb1 and Atf7IP form a hetero-trimeric complex that blocks Setdb1 nuclear export
伯克霍尔德菌假单胞菌OXA-57的结构与动力学：一种具有碳青霉烯水解活性的独特低效D类β-内酰胺酶	Bragginton, E.	PDF	N/A	Structure and dynamics of Burkholderia pseudomallei OXA-57, a distinctive low-efficiency class D β-lactamase with carbapenem-hydrolyzing activity
采用前沿检测技术的宽场光学氧化还原成像用于评估源自患者的癌症类器官	Gillette, A. A.	PDF	N/A	Wide-field optical redox imaging with leading-edge detection for assessment of patient-derived cancer organoids
N-氨基肽-石墨烯量子点负载的小型细胞外囊泡用于Tau病变靶向治疗	Zhu, R.	PDF	N/A	N-Amino Peptide-Graphene Quantum Dot Loaded Small Extracellular Vesicles for Targeted Therapy of Tauopathies
PRISM：一个用于多重组织微阵列交互式和集成分析的Python包	Tubelleza, R.	PDF	N/A	PRISM: A Python Package for Interactive and Integrated Analysis of Multiplexed Tissue Microarrays
药效团设计与集合对接方法在大规模数据库筛选中用于鉴定粪肠球菌APH(3')-IIIa潜在抑制剂	Velez, L. A.	PDF	N/A	Pharmacophore design and ensemble-docking as approach to screening a large-scale database for identification of potential inhibitors of APH(3')-IIIa of Enterococcus faecalis
基于代理的建模揭示了细胞粘附和基质重塑对癌症集体细胞迁移表型的影响	Benson, T. O.	PDF	N/A	Agent-based modeling reveals impacts of cell adhesion and matrix remodeling on cancer collective cell migration phenotypes
核小体间距能够微调更高阶的染色质组装	Chen, L.	PDF	N/A	Nucleosome Spacing Can Fine-Tune Higher Order Chromatin Assembly
估计由微血管驱动的皮质脑组织中的流体流速	Koch, T.	PDF	N/A	Estimation of fluid flow velocities in cortical brain tissue driven by the microvasculature
底栖硅藻运动模式的多样性	Bondoc-Naumovitz, K. G.	PDF	N/A	Diversity of motility patterns in benthic diatoms
CoREST复合物调控MYC的稳定性，并促进黑色素瘤中mRNA的转录后剪接。	Ryu, B.	PDF	N/A	The CoREST-complex regulates MYC stability and promotes post-transcriptional mRNA splicing in melanoma
肠道和免疫系统中雌激素介导炎症的数学建模	Lighty, A. M.	PDF	N/A	Mathematical Modeling of Estrogen-Mediated Inflammation in the Gut and Immune System
生命最初两年脑电微状态网络的时空动态：一项多队列纵向研究	Ghosh, P.	PDF	N/A	Spatiotemporal dynamics of EEG microstate networks over the first two years of life: A multi-cohort longitudinal study
真菌多于腿：首个食真菌千足虫（倍足纲）的真菌微生物组	Macias, A. M.	PDF	N/A	More fungi than legs: the first fungal microbiome for a fungus-eating millipede (Colobognatha)
KHNYN延伸的diKH结构域的结构和功能表征，用于介导ZAP抗病毒活性	Youle, R. L.	PDF	N/A	Structural and functional characterization of the KHNYN extended-diKH domain for mediating ZAP antiviral activity
细胞质中的半胱氨酰-tRNA合成酶能够调控ATF4的翻译，而不依赖于eIF2α的磷酸化状态。	Xu, A. E.	PDF	N/A	The cytosolic cysteinyl-tRNA synthetase is capable of regulating ATF4 translation independent of eIF2α phosphorylation state
代谢调控有助于痛觉感受器抵抗兴奋性毒性	Yuan, L.	PDF	N/A	Metabolic tuning facilitates nociceptor resilience to excitotoxicity
生物分子凝聚物控制并由RNA-RNA相互作用所定义，这些相互作用是在病毒复制过程中产生的。	Aierken, D.	PDF	N/A	Biomolecular condensates control and are defined by RNA-RNA interactions that arise in viral replication
单细胞细胞器提取与细胞索引	Lam, T.	PDF	N/A	Single-cell Organelle Extraction with Cellular Indexing
PAX2通过一种独特的表观遗传重编程机制被转录沉默，从而启动子宫内膜癌的发生。	Sahoo, S. S.	PDF	N/A	PAX2 is Transcriptionally Silenced by a Distinct Mechanism of Epigenetic Reprogramming to Initiate Endometrial Carcinogenesis
# BioRxiv 2024-12-22 Papers

标题	作者	PDF链接	代码仓库	Title
通过互信息识别的局部神经可塑性	Scheler, G.	PDF	N/A	Localist Neural Plasticity Identified By Mutual Information
微RNA-19b调控禽类前脑中的增殖与模式形成	Mishra, A.	PDF	N/A	microRNA-19b regulates proliferation & patterning in the avian forebrain
α-突触核蛋白C末端域的构象开关指导其纤维多态性	Aguirre, C.	PDF	N/A	Conformational switch in the alpha-synuclein C-terminus domain directs its fibril polymorphs
TET1能够减弱人类多能性相关的异质性，并增强分化能力。	Motono, M.	PDF	N/A	TET1 attenuates human pluripotency-related heterogeneities and enhances differentiation capabilities
通过数百万次实验室检测揭示的孕期和产后动态	Bar, A.	PDF	N/A	Pregnancy and postpartum dynamics revealed by millions of lab tests
对转录的超保守区域进行全面分析，揭示了新型非编码转录本在胶质瘤中的重要调控功能。	Gibert, M. K.	PDF	N/A	A comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas.
热抑制配子发生可以解释历史上幼体招募的崩溃现象。	Okamoto, D. K.	PDF	N/A	Thermal suppression of gametogenesis can explain historical collapses in larval recruitment
膜脂多不饱和性选择性地影响配体诱导的多巴胺D2受体内吞作用	Sposini, S.	PDF	N/A	Membrane lipid poly-unsaturation selectively affects ligand induced dopamine D2 receptor internalization
通过溶酶体运输开关协调调节激活素和骨形态发生蛋白信号传导	Hom, W. W.	PDF	N/A	Coordinate regulation of Activin and Bone Morphogenetic Protein signaling by a lysosomal trafficking switch
模拟研究了空间在药物敏感和药物耐受癌症细胞相互作用中的作用。	Pugh, K.	PDF	N/A	Simulations probe the role of space in the interplay between drug-sensitive and drug-resistant cancer cells
拯救DNMT1未能完全逆转其在小鼠胚胎干细胞中丧失所引起的分子和功能后果	Elder, E.	PDF	N/A	Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells
CellSeg3D：用于荧光显微镜的自监督3D细胞分割	Achard, C.	PDF	N/A	CellSeg3D: self-supervised 3D cellsegmentation for fluorescence microscopy
水稻盐胁迫响应的系统基因组学	Gupta, S.	PDF	N/A	System genomics of salinity stress response in rice
用于神经科学应用的纳米多孔铂微电极阵列	Winter-Hjelm, N.	PDF	N/A	Nanoporous Platinum Microelectrode Arrays for Neuroscience Applications
分子和空间转录组学分类中脑多巴胺神经元及其在帕金森病LRRK2G2019S模型中的改变	Gaertner, Z.	PDF	N/A	Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease
在动物体内针对特定基因组DNA序列进行靶向诱变，以生成变异库。	Falo-Sanjuan, J.	PDF	N/A	Targeted mutagenesis of specific genomic DNA sequences in animals for the in vivo generation of variant libraries
DNAH12的缺乏会导致雄性不育，因为它会损害DNAH1和DNALI1在人类和小鼠中的招募。	Yang, M.	PDF	N/A	Deficiency in DNAH12 causes male infertility by impairing DNAH1 and DNALI1 recruitment in humans and mice
一种高效预测自然物体感知相似度的高通量方法	Kaniuth, P.	PDF	N/A	A high-throughput approach for the efficient prediction of perceived similarity of natural objects
用于研究人胶质-神经元及大胶质-小胶质相互作用的人-鼠嵌合脑模型	Jin, M.	PDF	N/A	Human-Mouse Chimeric Brain Models to Study Human Glial-Neuronal and Macroglial-Microglial Interactions
改变的B细胞代谢途径特征化1型糖尿病的进展	Conway, H.	PDF	N/A	Altered B Cell Metabolic Pathways Characterize Type 1 Diabetes Progression
微囊藻中标记基因及细胞内无定形碳酸钙生物矿化候选基因的昼夜表达变化	Bruley, A.	PDF	N/A	Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis
T细胞在角质形成细胞和真皮成纤维细胞中促进皮肤炎症性疾病的不同转录程序。	DeBerg, H. A.	PDF	N/A	T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblasts
Hao-Fountain综合征蛋白USP7通过BCOR-ncPRC1.1调控神经分化。	Wolf van der Meer, J.	PDF	N/A	Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR-ncPRC1.1
雷帕霉素减少动脉矿物密度并促进有益的血管重塑在小鼠重度中膜动脉钙化模型中	Behzadi, P.	PDF	N/A	Rapamycin Reduces Arterial Mineral Density and Promotes Beneficial Vascular Remodeling in a Murine Model of Severe Medial Arterial Calcification
中心纺锤体和Ect2的系统发育学与结构建模为后生动物和多细胞性的出现提供了机制上的见解。	Glotzer, M.	PDF	N/A	Phylogenetics and structural modeling of Centralspindlin and Ect2 provides mechanistic insights into the emergence of Metazoa and multicellularity
RNA聚合酶III中与TFIIE相关的串联双翼螺旋结构的多功能性基础	Wu, J.-S.	PDF	N/A	Structural underpinning of multi-functionality of TFIIE-related tandem-winged-helix in RNA polymerase III
将种内变异整合到种群动态中，揭示了相互作用的物种如何在互利共生群落中持续存在。	Arroyo-Correa, B.	PDF	N/A	Integrating intraspecific variation into population dynamics reveals how interacting species persist in mutualistic communities
毫秒级的运动编码先于鸣禽的感觉运动学习	Pascual, L. M.	PDF	N/A	Millisecond-scale motor coding precedes sensorimotor learning in songbirds
O特异性抗原的丧失影响了铜绿假单胞菌在鼠类临床前肺部感染模型中的微生物地理分布。	Fraser, H.	PDF	N/A	Loss of O-specific antigen shapes Pseudomonas aeruginosa microbiogeography in murine preclinical pulmonary infection model
新发现的鼠CD103-树突状细胞是高免疫原性的常规DC2亚群，对应于已知的小鼠和人类中的树突状细胞亚群。	Sawanobori, Y.	PDF	N/A	Newly found rat CD103- dendritic cells are the highly immunogenic conventional DC2 subpopulation, corresponding to the known DC subsets in mice and humans.
在细菌噬菌体代谢劫持的全基因组模型中的协同作用与拮抗作用	Rozum, J. C.	PDF	N/A	Synergy and antagonism in a genome-scale model of metabolic hijacking by bacteriophage
Remodelin对小鼠肌细胞分化的抑制作用	Sian, V.	PDF	N/A	The inhibitory effects of Remodelin on murine myoblasts differentiation
一个用于生成多维3D对象并精细控制特征空间的工具箱：Quaddle 2.0	Wen, X.	PDF	N/A	A Toolbox for Generating Multidimensional 3-D Objects with Fine-Controlled Feature Space: Quaddle 2.0
Spatial-DC：一种基于深度学习的稳健方法，用于空间蛋白质组学的反卷积	Li, Y.	PDF	N/A	Spatial-DC: a robust deep learning-based method for deconvolution of spatial proteomics
脑脊液和血浆中apoE糖基化水平的增加与阿尔茨海默病生物标志物水平的降低有关。	Nedelkov, D.	PDF	N/A	Increased cerebrospinal fluid and plasma apoE glycosylation is associated with reduced levels of Alzheimer's disease biomarkers
细菌表面上的Hemin结合DNA结构促进了胞外电子传递。	Ajunwa, O. M.	PDF	N/A	Hemin-binding DNA structures on the surface of bacteria promote extracellular electron transfer
混合细胞群体的自发趋化性	Ucar, M. C.	PDF	N/A	Self-generated chemotaxis of mixed cell populations
鲲鹏：一种超内存高效、快速且准确的泛域分类器，适用于所有分类任务	Chen, Q.	PDF	N/A	Kun-peng: an ultra-memory-efficient, fast, and accurate pan-domain taxonomic classifier for all
脑场电位的不规则指数取决于所估计的频率范围。	Boncompte, G.	PDF	N/A	Aperiodic exponent of brain field potentials is dependent on the frequency range it is estimated
用于利用高光谱卫星影像绘制沿海湿地中S. salsa分布的碱蓬高光谱指数（SSHI）	zhang, m.	PDF	N/A	Suaeda Salsa Hyperspectral Index (SSHI) for mapping S. salsa in coastal wetlands using hyperspectral satellite imagery
在厄瓜多尔低山热带雨林中蕨类的低度及兼性菌根化	Michel, J.	PDF	N/A	Low and facultative mycorrhization of ferns in a low-montane tropical rainforest in Ecuador
热应激促使六射珊瑚中病毒和抗病毒先天免疫的快速激活	Sharoni, T.	PDF	N/A	Heat stress drives rapid viral and antiviral innate immunity activation in Hexacorallia
通过在近红外IIb窗口放大检测miRNA-21实现早期慢性结肠炎癌变的无创诊断	Zhai, F.	PDF	N/A	Non-invasive diagnosis of early chronic colitis cancerization via amplified sensing of miRNA-21 in NIR-IIb window
ASMS：无需基因分型即可在人类基因组中寻找等位基因特异性甲基化	Raineri, E.	PDF	N/A	ASMS: finding allele specific methylation in human genomes without phasing
纤维化的肺尘灶是在一项为期两年的吸入研究中，由二氧化钛纳米颗粒引起的大鼠晚期尘肺病变。	Yamano, S.	PDF	N/A	Fibrotic pulmonary dust foci is an advanced pneumoconiosis lesion in rats induced by titanium dioxide nanoparticles in a 2-year inhalation study
在肯尼亚农村，教师和看护者在通过游戏促进儿童早期学习和发展的认知与角色。	Otwate, P. W.	PDF	N/A	The perceptions and roles of teachers and caregivers on play in promoting children's early learning and development in rural Kenya
基因调控网络与多组学数据的整合提升了癌症生存预测的准确性	Pop, R. T.	PDF	N/A	Gene regulatory network integration with multi-omics data enhances survival predictions in cancer
可遗传免疫接种为病原体控制建立了一种新模式	Buchthal, J.	PDF	N/A	Heritable Immunization Establishes a New Model for Pathogen Control
氯化多环芳烃的量子化学性质用于delta机器学习	Frolov, D.	PDF	N/A	Quantum chemical properties of chlorinated polycyclic aromatic hydrocarbons for delta machine learning
从弱相互作用到强亲和力：通过核磁共振和计算分析解读链霉亲和素-生物素相互作用	Ptaszek, A. L.	PDF	N/A	From Weak Interactions to Strong Affinity: Deciphering the Streptavidin-Biotin Interaction through NMR and ComputationalAnalysis
一个受生物启发的分层卷积能量模型预测了V4对自然视频的响应	Gallant, J. L.	PDF	N/A	A biologically-inspired hierarchical convolutional energy model predicts V4 responses to natural videos
一线标准治疗药物对杀菌反应、耐药性出现及治愈在小鼠易治或难治性结核病模型中的贡献	Peroutka-Bigus, N.	PDF	N/A	Contribution of front-line, standard of care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease
卡尺：用于表型实验和再生研究的细胞周期感知活体成像技术	Di Sante, M.	PDF	N/A	CALIPERS: Cell cycle-aware live imaging for phenotyping experiments and regeneration studies
GeneSetCluster 2.0：一个全面的工具集，用于总结和整合基因集分析	Ortega-Legarreta, A.	PDF	N/A	GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysis
TrimNN：表征细胞群落基序，用于研究复杂组织中多细胞拓扑结构	Yu, Y.	PDF	N/A	TrimNN: Characterizing cellular community motifs for studying multicellular topological organization in complex tissues
一种可注射的壳聚糖水凝胶能够在肿瘤内局部定位并可调节地释放免疫治疗药物，从而消除经过治疗和远端效应的小鼠三阴性乳腺癌肿瘤。	Mantooth, S. M.	PDF	N/A	An injectable chitosan hydrogel localizes and tunably releases immunotherapeutics intratumorally eliminating both treated and abscopal murine triple negative breast tumors
补充花卉资源并不能缓解城市化对巢穴筑巢的蜜蜂和黄蜂的负面影响。	Ellis, E. E.	PDF	N/A	Supplementing floral resources does not mitigate the negative effects of urbanisation on cavity-nesting bees and wasps.
突破界限：新记录的分布地及对印度东北部梅加拉亚邦特有物种——卡西山蟾蜍（Bufoides meghalayanus）保护状况的重新评估	Sengupta, S.	PDF	N/A	Breaking Boundaries: New locality records and a reassessment of the conservation status of the Khasi Hill Toad (Bufoides meghalayanus) endemic to Meghalaya, Northeast India
基因调控网络及从头起源基因的关键转录因子	Peng, J.	PDF	N/A	Gene regulatory networks and essential transcription factors for de novo originated genes
在清醒、不受束缚的猫中进行非连续神经调节可增加膀胱容量	Ortiz Lopez, M.	PDF	N/A	Non-continuous neuromodulation in awake, unrestrained felines increases bladder capacity
闭链肩部模型的个性化能够为多种运动提供高精度的运动学准确性。	Hammond, C. V.	PDF	N/A	Personalization of Closed-Chain Shoulder Models Yields High Kinematic Accuracy for Multiple Motions
植物可视化平台：一个综合的基于网络的工具，用于整合、可视化和分析植物及相关物种的组学数据	Santiago, A.	PDF	N/A	The Plantae Visualization Platform: a comprehensive web-based tool for the integration, visualization, and analysis of omic data across plant and related species
植物可视化平台：一个综合的基于网络的工具，用于整合、可视化和分析跨植物及相关物种的组学数据。	Santiago, A.	PDF	N/A	The Plantae Visualization Platform: a comprehensive web-based tool for the integration, visualization, and analysis of omic data across plant and related species
PHACE：基于系统发育的协同进化分析	Kuru, N.	PDF	N/A	PHACE: Phylogeny-Aware Co-Evolution
家谱画家（PePa）：一种用于在染色体背景下可视化遗传继承的工具。	Pozzi, A.	PDF	N/A	Pedigree Painter (PePa): a tool for the visualization of genetic inheritance in chromosomal context
家谱画家（PePa）：一种用于在染色体背景下可视化遗传继承的工具。	Pozzi, A.	PDF	N/A	Pedigree Painter (PePa): a tool for the visualization of genetic inheritance in chromosomal context
MultiNMRFit：一款用于拟合一维和伪二维核磁共振谱的软件	Millard, P.	PDF	N/A	MultiNMRFit: A software to fit 1D and pseudo-2D NMR spectra
ETV5的T505A变体在急性淋巴细胞白血病的鼠模型中促进前B细胞的增殖。	Yi, J.	PDF	N/A	T505A variant of ETV5 promotes proliferation of precursor B cells in a mouse model of acute lymphoblastic leukemia
利用氧化途径改造酿酒酵母使其能在木糖上生长	Tanaka, K.	PDF	N/A	Engineering Saccharomyces cerevisiae for growth on xylose using an oxidative pathway
学习人类基因组中配对的表观基因组与转录因子结合关联评分	Kwon, S. B.	PDF	N/A	Learning a Pairwise Epigenomic and Transcription Factor Binding Association Score Across the Human Genome
研究牛津纳米孔长读长测序相对于Illumina微阵列和短读长测序的性能	Santos, R.	PDF	N/A	Investigating the performance of Oxford Nanopore long-read sequencing with respect to Illumina microarrays and short-read sequencing
α-突触核蛋白纤维在S129位点的磷酸化改变了DNAJB1的结合，这一现象通过固态核磁共振技术得以探测。	Pacheco, S.	PDF	N/A	Phosphorylation of α-synuclein fibrils at S129 changes DNAJB1 binding as probed by solid-state NMR
骨骼肌干细胞中目标性SMN不足介导了长期的非细胞自主性运动神经元丧失	Mecca, J.	PDF	N/A	Targeted-SMN insufficiency in Skeletal Muscle Stem Cells mediates non-cell autonomous loss of motor neurons at long term
Anxa1+ 多巴胺能神经元的脆弱性定义了帕金森病前驱期的运动迟缓和程序性运动学习障碍。	Mantas, I.	PDF	N/A	Anxa1+ dopamine neuron vulnerability defines prodromal Parkinson's disease bradykinesia and procedural motor learning impairment
P2Y2嘌呤能受体和DNA传感器cGAS共同调控电离辐射介导的促炎性巨噬细胞激活。	Mostefa-Kara, A.	PDF	N/A	P2Y2 purinergic receptor and DNA sensor cGAS dictate ionizing radiation-mediated proinflammatory macrophage activation
SETDB6介导的AuroraB激酶甲基化调控细胞分裂期并保护细胞免受染色体不稳定性。	Feldman, M.	PDF	N/A	AuroraB-kinase methylation by SETD6 regulates cytokinesis and protects cells from chromosomal instability
珍珠驱动线粒体DNA核分布	Landoni, J. C.	PDF	N/A	Pearling Drives Mitochondrial DNA Nucleoid Distribution
使用单细胞qRT-PCR对成年小鼠心脏基质细胞进行转录组分析	Alonaizan, R.	PDF	N/A	Transcriptomic analysis of adult mouse cardiac stromal cells using single-cell qRT-PCR
顺序至关重要：温度的自相关性决定了具有非线性热性能的种群的灭绝风险。	Robey, A. J.	PDF	N/A	Order matters: Autocorrelation of temperature dictates extinction risk in populations with nonlinear thermal performance
拉丁美洲间日疟原虫和辛氏疟原虫宿主转移的基因组学洞察	Lefebvre, M. J. M.	PDF	N/A	Genomic insights into Plasmodium vivax and Plasmodium simium host shifts in Latin America
绘制S. cerevisiae中适应性综合应激反应的遗传架构图	Baum, R.	PDF	N/A	Mapping the Genetic Architecture of the Adaptive Integrated Stress Response in S. cerevisiae
MrHAMER2：高精度长读长RNA测序技术，用于解析病毒转录本在潜伏期中的特定异构体变异	Gallardo, C. M.	PDF	N/A	MrHAMER2: high-accuracy long-read RNA sequencing to decode isoform-specific variation in viral transcripts during latency
多组学基础模型通过零样本预测表观遗传调控	Yang, Z.	PDF	N/A	Multiomic foundation model predicts epigenetic regulation by zero-shot
啮齿动物电子尼古丁输送系统：一种仅限鼻吸入电子烟气溶胶的装置的描述与验证，适用于自由活动的大鼠	Odum, A. L.	PDF	N/A	The Rodent Electronic Nicotine Delivery System: Description and Validationof an Apparatus for Nose-Only E-Cigarette Aerosol Inhalation in Freely Moving Rats
解决方案生物物理学揭示了脂质纳米颗粒的非球形性、多分散性以及其内部有序性对有效mRNA递送的依赖性。	Padilla, M.	PDF	N/A	Solution biophysics identifies lipid nanoparticle non-sphericity, polydispersity, and dependence on internal ordering for efficacious mRNA delivery
OmiGA：一种用于复杂群体中超高效分子性状分析的工具包	Teng, J.	PDF	N/A	OmiGA: A Toolkit for Ultra-efficient Molecular Trait Analysis in Complex Populations
评分信息整合与统计质量控制增强的跨运行分析在数据独立采集蛋白质组学数据中的应用	Gao, M.	PDF	N/A	Scoring Information Integration with Statistical Quality Control Enhanced Cross-Run Analysis of Data-Independent Acquisition Proteomics Data
通过无监督网络嵌入推断果蝇多感官路径的社区结构	Sun, X.	PDF	N/A	Inferring community architectures of multisensory pathways in Drosophila via unsupervised network embedding
使用变分自编码器来表征由于抗生素治疗而产生的异质性亚群	BERSENEV, D.	PDF	N/A	The use of variational autoencoders to characterise the heterogeneous subpopulations that arise due to antibiotic treatment
线粒体珍珠化的生物物理机制	Sturm, G.	PDF	N/A	The biophysical mechanism of mitochondrial pearling
有丝分裂染色体的外周：一种介导染色体力学的流体外套	Mendonca, T.	PDF	N/A	The mitotic chromosome periphery: a fluid coat that mediates chromosome mechanics
在小鼠结肠炎模型中，饮食中铁的剥夺与补充的比较分析	Medjbeur, T.	PDF	N/A	Comparative analysis of dietary iron deprivation and supplementation in a murine model of colitis
化学遗传学调控揭示了细胞命运编程的最佳MAPK信号传导	Lende-Dorn, B. A.	PDF	N/A	Chemogenetic tuning reveals optimal MAPK signaling for cell-fate programming
经典血清素类致幻剂作用下定向功能层次的崩塌	Vohryzek, J.	PDF	N/A	Collapse of directed functional hierarchy under classical serotonergic psychedelics
应激诱导的内皮细胞线粒体碎片化破坏了血视网膜屏障的完整性，导致神经退行性变。	Cueva Vargas, J. L.	PDF	N/A	Stress-induced mitochondrial fragmentation in endothelial cells disrupts blood-retinal barrier integrity causing neurodegeneration.
B细胞激活的蛋白质组图谱及其受mTORC1、MYC和铁调控的塑造	James, O.	PDF	N/A	A proteomic map of B cell activation and its shaping by mTORC1, MYC and iron
绘制人类内分泌胰腺在出生后早期各阶段的组织学和功能成熟图谱	Saunders, D. C.	PDF	N/A	Mapping histological and functional maturation of human endocrine pancreas across early postnatal periods
使用扩展谱系模型检测线粒体DNA效应：统计功效与估计偏差的分析	Lyu, X.	PDF	N/A	Detecting mtDNA effects with an Extended Pedigree Model: An Analysis of Statistical Power and Estimation Bias
与果蝇相关的宏基因组组装基因组中的系统发育和功能多样性	Comeault, A. A.	PDF	N/A	Phylogenetic and functional diversity among Drosophila-associated metagenome-assembled genomes
人类基因组中的大型复杂结构重排隐藏着隐秘的结构	Audano, P. A.	PDF	N/A	Large complex structural rearrangements in human genomes harbor cryptic structures
HapCNV：一种用于低输入DNA测序数据CNV检测的综合框架	Yu, X.	PDF	N/A	HapCNV: A Comprehensive Framework for CNV Detection in Low-input DNA Sequencing Data
棘阿米巴卡氏体中亚马逊利什曼原虫的摄取与存活：一种感染生物模型？	Geres, L. F.	PDF	N/A	Uptake and survival of Leishmania amazonensis in Acanthamoeba castellanii: An infection organism model?
全球潜在功能性病毒辅助代谢基因的多样性及其与土壤有机碳储量的关系	Merges, D.	PDF	N/A	Global diversity of putative functional viral auxiliary metabolic genes and their relationship with soil organic carbon stocks
病原体在面对先天免疫记忆时的实验进化增加了毒力的变异	Korsa, A.	PDF	N/A	Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence
通过植物标本数据和公民科学数据库揭示的过去几十年中蓝羽扇豆（Lupinus angustifolius）开花时间提前的证据	Jimenez-Lopez, F. J.	PDF	N/A	Evidence of flowering time advance in blue lupin (Lupinus angustifolius) in the last decades revealed by herbarium data and citizen science databases
采蜜黄蜂的陷阱采集行为	Lacombrade, M.	PDF	N/A	Trapline foraging by nectar-collecting hornets
时空光催化邻近标记蛋白质组学揭示配体激活的细胞外和细胞内EGFR邻域	Lin, Z.	PDF	N/A	Spatiotemporal photocatalytic proximity labeling proteomics reveals ligand-activated extracellular and intracellular EGFR neighborhoods
双特异性抗体靶向脂质纳米颗粒	Amabile, A.	PDF	N/A	Bispecific antibody targeting of lipid nanoparticles
使用大型语言模型生成抗原特异性配对的重链和轻链抗体序列	Wasdin, P. T.	PDF	N/A	Generation of antigen-specific paired heavy-light chain antibody sequences using large language models
HMG-DTI：一种结合层次分子图和改进卷积块注意力模块的药物-靶标相互作用预测框架	Yang, Z.	PDF	N/A	HMG-DTI: a drug-target interaction prediction framework combining Hierarchical Molecular Graphs and improved Convolutional Block Attention Module
短的激活域控制转录因子与染色质的结合	Fan, V.	PDF	N/A	Short activation domains control chromatin association of transcription factors
高风险膀胱癌的基因组和转录组分析揭示了多样的分子和微环境生态系统	Methani, K.	PDF	N/A	Genomic and transcriptomic profiling of high-risk bladder cancer reveals diverse molecular and microenvironment ecosystems
高风险膀胱癌的基因组和转录组分析揭示了多样化的分子和微环境生态系统	Meghani, K.	PDF	N/A	Genomic and transcriptomic profiling of high-risk bladder cancer reveals diverse molecular and microenvironment ecosystems
拟南芥EID1 E3泛素连接酶通过调节HSBP的转位来调控获得性耐热性。	Tu, Y.-T.	PDF	N/A	Arabidopsis EID1 E3 ubiquitin ligase regulates acquired thermotolerance by modulating HSBP translocation
同一张幻灯片的空间多组学整合揭示了肿瘤病毒相关的肿瘤微环境空间重组	Yeo, Y. Y.	PDF	N/A	Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment
PI3Kγ通路有助于寨卡病毒感染引起的神经炎症和神经元死亡。	Teixeira, D. C.	PDF	N/A	PI3Kγ pathway contributes to neuroinflammation and neuronal death induced by Zika virus infection
新生仔猪和断奶仔猪通过联合口服和鼻内途径接种两种PEDV（S INDEL和非S INDEL）后，先天免疫反应的作用	Lopez-Figueroa, C.	PDF	N/A	The role of innate immune responses against two strains of PEDV (S INDEL and non-S INDEL) in newborn and weaned piglets inoculated by combined orogastric and intranasal routes
通过回顾性分析美国东北部黑秃鹫不明原因死亡事件中的元基因组测序，发现了一种新型蝙蝠病毒。	Mwakibete, L.	PDF	N/A	Discovery of a novel bandavirus using metagenomic sequencing in a retrospective analysis of an unresolved 2020 mortality event involving black vultures in the northeastern United States.
KIF18A在肝细胞癌转移中的双重作用：抗失巢凋亡和染色体不稳定性	Kan, C.	PDF	N/A	KIF18A in HCC Metastasis: Dual Role in Anoikis Resistance and Chromosome Instability
围产期暴露于纳米聚苯乙烯对炎症性肠病的有害印记	Airaud, M.	PDF	N/A	Deleterious imprinting of perinatal exposure to nano-polystyrene on inflammatory bowel diseases
将裸盖菇素描述为对雄性和雌性大鼠青春期抗抑郁的特性	Garcia-Cabrerizo, R.	PDF	N/A	Characterizing psilocybin as an antidepressant for adolescence in male and female rats
加利福尼亚海狮在人类照料下的眼部疾病流行率：淡水与盐水环境对比	Brehm, I.	PDF	N/A	Ocular Disease Prevalence in California Sea Lions In Human Care: Freshwater Versus Saltwater Housing
CAR-T疗法后免疫抑制微环境的获得导致T细胞功能障碍和耐药性	Ponzo, M.	PDF	N/A	Acquisition of an immunosuppressive microenvironment after CAR-T therapy drives T-cell dysfunction and resistance
通过大规模分析天然配对的人类抗体序列和结构数据，揭示了保守的重/轻链接触和胚系偏好。	Dudzic, P.	PDF	N/A	Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data.
气候变化与人为因素对未来入侵风险的影响对比：一种独居蜂Amegilla pulchra的案例	Dubos, N.	PDF	N/A	Contrasted effect of climate and anthropogenic change on future invasion risk of a solitary bee Amegilla pulchra
释放策略影响养殖场培育的幼年大鳞大麻哈鱼的淡水栖息和生存。	Balfour, T. J. B.	PDF	N/A	Release strategies affect the freshwater residence and survival of hatchery-reared juvenile Chinook Salmon
入侵植物与蜂鸟和花螨网络的整合是由生态适应和泛化驱动的。	Garcia-Robledo, C.	PDF	N/A	Integration of an invasive plant in hummingbird and flower mite networks is driven by ecological fitting and generalization
在珊瑚白化期间，使用RGB颜色指数作为共生体细胞密度和叶绿素含量的代理指标。	Ferrara, E. F.	PDF	N/A	RGB color indices as proxy for symbiont cell density and chlorophyll content during coral bleaching
实验适应性辐射在羽虱隐色现象中的基因组学研究	Baldwin-Brown, J. G.	PDF	N/A	Genomics of experimental adaptive radiation in the cryptic coloration of feather lice
智利巴塔哥尼亚北部地区Eleginops maclovinus的基因组信号中的局部适应性	Claure, C. E.	PDF	N/A	Genomic signals of local adaptation in Eleginops maclovinus from Northern Chilean Patagonia
无约束条件下视频中鸟类头部运动的自动分析	Santos-Lopes, M.	PDF	N/A	Automated Analysis of Bird Head Motion from Videos in Unconstrained Settings
使用CRISPR/Cas9进行单倍型编辑作为治疗NEFL显性负性错义突变的一种方法	Dua, P. H.	PDF	N/A	Haplotype editing with CRISPR/Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL
利用EasyGuide CRISPR系统为大肠杆菌在蔗糖上生长设计适应性等位基因	Barreto, J. A.	PDF	N/A	Engineering Adaptive Alleles for Escherichia coli Growth on Sucrose Using the EasyGuide CRISPR System
希腊白纹伊蚊线粒体基因组多样性与系统发育见解	BALATSOS, G.	PDF	N/A	Mitogenome Diversity and Phylogenetic Insights of Aedes albopictus in Greece
原始方案：开源社区资源，用于低成本病毒基因组测序	Kent, C.	PDF	N/A	PrimalScheme: open-source community resources for low-cost viral genome sequencing
生物制造空间组织化的颞下颌关节纤维软骨组件	Dufour, A.	PDF	N/A	Biofabrication of spatially organized temporo-mandibular fibrocartilage assembloids
创建微生物组模型和谐：在两步厌氧消化器中，将元蛋白质组数据与ADM1da相结合	Hellwig, P.	PDF	N/A	Creating microbiome-model harmony between metaproteomics data and the ADM1da for a two-step anaerobic digester
开发用于芯片上器官应用的柔性3D打印TPU-PVC微流体装置	ABDALKADER, R. K.	PDF	N/A	Development of a flexible 3D printed TPU-PVC microfluidic devices for organ-on-a-chip applications
基因组挖掘算法用于识别相同的重复序列，以开发灵敏且特异性的传染病诊断方法	Rajeswari, K.	PDF	N/A	Genome-mining algorithm to identify identical repetitive sequences for sensitive and specific diagnostic assays for infectious diseases
随机空间主成分分析（RASP）：一种用于高分辨率空间转录组数据降维的计算高效方法	Gingerich, I. K.	PDF	N/A	Randomized Spatial PCA (RASP): a computationally efficient method for dimensionality reduction of high-resolution spatial transcriptomics data
Verkko2：将邻近连接数据与长读长De Bruijn图整合，用于高效的端粒到端粒基因组组装、相位确定和支架搭建。	Phillippy, A. M.	PDF	N/A	Verkko2: Integrating proximity ligation data with long-read De Bruijn graphs for efficient telomere-to-telomere genome assembly, phasing, and scaffolding
CESA：跨物种表位序列分析，用于发现可用于模式生物中磷酸化特异性蛋白质检测的现有抗体	Hu, Y.	PDF	N/A	CESA: Cross-species Epitope Sequence Analysis for discovery of existing antibodies useful for phospho-specific protein detection in model species
HAPP：高精度管道，用于处理深度元条形码数据	Sundh, J.	PDF	N/A	HAPP: High-Accuracy Pipeline for Processing deep metabarcoding data
癌症驱动基因的共本质性网络更好地优先考虑抗癌药物	Lee, K.	PDF	N/A	A Co-essentiality Network of Cancer Driver Genes Better Prioritizes Anticancer Drugs
用于细胞计算机模拟基因扰动的AI模型基准测试	Li, C.	PDF	N/A	Benchmarking AI Models for In Silico Gene Perturbation of Cells
具有更大序列库的高速10重DNA-PAINT技术	Banerjee, A.	PDF	N/A	High-speed 10-plex DNA-PAINT with a larger sequence repertoire
直接观察触发响应型脂酶生物杂合体的组装与功能	Voutyritsa, E.	PDF	N/A	Direct observation of assembly and function of trigger responsive lipase biohybrids
空间转录组学探索神经母细胞瘤原发微环境揭示了新的旁分泌相互作用	Siaw, J. T.	PDF	N/A	Spatial transcriptomics exploration of the primary neuroblastoma microenvironment unveils novel paracrine interactions
使用β放射性配体疗法和4Ig-B7-H3异构体特异性靶向进行抗癌免疫启动	Glazer, S. E.	PDF	N/A	Anti-Cancer Immune Priming with Beta-Radioligand Therapy and Isoform-Selective Targeting of 4Ig-B7-H3
法尼基转移酶抑制剂KO-2806使复发的肿瘤重新对RAS抑制敏感。	Patel, H. V.	PDF	N/A	The farnesyl transferase inhibitor KO-2806 re-sensitizes relapsing tumors to RAS inhibition
白血病通过在新生抗原特异性CD4+ T细胞上强加一种1型调节程序来逃避免疫。	Venkatesh, H.	PDF	N/A	Leukemia escapes immunity by imposing a Type-1 regulatory program on neoantigen-specific CD4+ T cells.
SMAD4突变促使肠道微生物群向促进结直肠癌肿瘤进展的方向转变	Gates, T. J.	PDF	N/A	SMAD4 Mutation Drives Gut Microbiome Shifts Toward Tumor Progression in Colorectal Cancer
DUSP6在转移中被上调，并影响胰腺癌细胞的迁移和代谢。	Tannus Ruckert, M.	PDF	N/A	DUSP6 is upregulated in metastasis and influences migration and metabolism in pancreatic cancer cells
高强度化疗通过反向电子传递引发心脏毒性	Pinto, C.	PDF	N/A	Intensive Chemotherapy Induces Cardiotoxicity via Reverse Electron Transport
双域植物防御素MtDef5衍生的肽的作用方式及其生物杀菌剂潜力	Kalunke, R. M.	PDF	N/A	Modes of action and bio-fungicide potential of peptides derived from the bi-domain plant defensin MtDef5
在顺铂耐药细胞系中，柠檬酸治疗逆转顺铂耐药性	Chaturvedi, S.	PDF	N/A	Cisplatin resistance reversal with treatment of Citric acid in cisplatin-resistant cell lines
两种神经肽信号传导调控雄性蟋蟀的交配后拒绝行为及生殖系统	Zhu, Z.	PDF	N/A	Two neuropeptide signalings regulate post-mating refusal behavior and reproductive system in male crickets
Septin细胞骨架是一种新发现的调控肠道上皮屏障完整性和黏膜炎症的机制。	Naydenov, N. G.	PDF	N/A	The Septin Cytoskeleton is a Novel Regulator of Intestinal Epithelial Barrier Integrity and Mucosal Inflammation
多组学图谱揭示了细胞毒性表型和与活性氧相关的代谢静止作为CTL抵抗的HIV感染CD4+ T细胞的关键特征。	Herrera, A.	PDF	N/A	Multi-Omic Atlas reveals cytotoxic phenotype and ROS-linked metabolic quiescence as key features of CTL-resistant HIV-infected CD4+ T-cells
发现一种新型结合模式和作用机制的高效选择性人类NLRP3抑制剂	Wilhelmsen, K.	PDF	N/A	Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action
胸腺退化作为一种适应性策略，用于对抗多种病原体。	Iwasa, Y.	PDF	N/A	Thymic involution as an adaptive schedule for combating diverse pathogens.
菌株水平的抗原变异有助于Bacteroides thetaiotaomicron的免疫逃避。	Glowacki, R. W. P.	PDF	N/A	Strain-level antigen variation facilitates immune evasion in Bacteroides thetaiotaomicron
SOD1 控制中性粒细胞的氧化爆发和微生物杀灭。	Foti, A.	PDF	N/A	SOD1 controls neutrophil oxidative burst and microbial killing
在小鼠巨噬细胞中，不同微环境下的性别二态性基因调控	McGill, C. J.	PDF	N/A	Sex-dimorphic gene regulation in murine macrophages across niches
Ilastik：一个用于跨多个脊椎动物物种探究干细胞命运决定的机器学习图像分析平台	Zuniga Munoz, A.	PDF	N/A	Ilastik: a machine learning image analysis platform to interrogate stem cell fate decisions across multiple vertebrate species
通过玻璃化方法测试各种冷冻保护剂组合用于人体皮肤冷冻保存	Riabinin, A.	PDF	N/A	Testing various combinations of cryoprotective agents for human skin cryopreservation by vitrification method
整合捕食者的能量平衡、冒险行为和微生境于功能反应中：解开多物种脊椎动物群落中的间接相互作用	Beardsell, A.	PDF	N/A	Integrating predator energetic balance, risk-taking behavior and microhabitat in functional response: Untangling indirect interactions in a multispecies vertebrate community
STAT5B白血病突变，改变SH2酪氨酸665，对免疫基因程序产生相反的影响。	Lee, H. K.	PDF	N/A	STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs
转录调控位点塑造拟南芥基因表达可塑性的自然变异	Lensink, M. E.	PDF	N/A	Trans-regulatory loci shape natural variation of gene expression plasticity in Arabidopsis
遗传学分析表明，绿蝇（Lucilia cuprina）的幼虫和成虫阶段使用不同的感觉系统。	Wulff, J. P.	PDF	N/A	Genetic analyses suggest that larval and adult stages of Lucilia cuprina employ different sensory systems
SenSet是一种新型的人类肺衰老细胞基因特征，能够识别细胞特异性的衰老机制。	Hasanaj, E.	PDF	N/A	SenSet, a novel human lung senescence cell gene signature, identifies cell-specific senescence mechanisms
在社区范围内多次治疗后蛔虫的分子流行病学：谁感染了谁？	Landeryou, T.	PDF	N/A	Molecular epidemiology of Ascaris lumbricoides following multiple rounds of community-wide treatment: who infects whom?
一种用于热带爪蟾（Xenopus tropicalis）的表观遗传时钟揭示了与年龄相关的位点，这些位点在H4K20me3标记的异染色质中富集。	Bennett, R.	PDF	N/A	An epigenetic clock for Xenopus tropicalis reveals age-associated sites enriched in H4K20me3-marked heterochromatin
结构解析ADAM17-iRhom2复合物的激活与抑制机制	Maciag, J. J.	PDF	N/A	Structural Insights into the Activation and Inhibition of the ADAM17-iRhom2 Complex
液态与气态阳极零间隙生物电解池的对比研究	Rohbohm, N.	PDF	N/A	A comparison study between liquid- and vapor-fed anode zero-gap bioelectrolysis cells
扩展毛细管工具箱：3D打印的微流体相导管和自聚合模块	Craig, C.	PDF	N/A	Expanding the capillarics toolbox: 3D-printed microfluidic phaseguides and self-coalescence modules
生物医学应用中的Xolography技术：双色光片打印水凝胶，实现形状和硬度的局部控制	Stoecker, L.	PDF	N/A	Xolography for Biomedical Applications: Dual-color Light-sheet Printing of Hydrogels with Local Control over Shape and Stiffness
蛋白质CREATE实现了从头合成蛋白质结合剂的闭环设计。	Lourenco, A. L.	PDF	N/A	Protein CREATE enables closed-loop design of de novo synthetic protein binders
异源表达梭菌属的二氧化碳脱氢酶基因以增强醋酸和酒精从二氧化碳中的生产	Tharak, A.	PDF	N/A	Heterologous Expression of the carbon monoxide dehydrogenase Gene from Clostridium sp. to Enhance Acetic Acid and Alcohol Production from CO2
用于实时成像、手术引导及脑肿瘤复发监测的超声声学肿瘤涂料	Rabut, C.	PDF	N/A	Acoustic tumor paint for real-time imaging, surgical guidance and recurrence monitoring of brain tumors with ultrasound
MRS-Sim：用于模拟类似体内真实磁共振波谱数据的开放源代码框架	LaMaster, J. T.	PDF	N/A	MRS-Sim: Open-Source Framework for Simulating Realistic In Vivo-like MR Spectroscopy Data
独特的细胞核与细胞质转录组特征揭示，仅靠转录本身不足以决定葡萄糖诱导的转录组动态变化	Bagheri, A.	PDF	N/A	Distinct Nuclear and Cytoplasmic Transcriptomic Signatures Reveal Transcription Alone Is Insufficient to Determine Glucose-Induced Transcriptomic Dynamics
"All of Us研究计划"队列中的遗传祖先和人群结构	Sharma, S.	PDF	N/A	Genetic ancestry and population structure in the All of Us Research Program cohort
singIST：一种综合方法，用于比较疾病模型与人类之间的单细胞转录组学	Moruno-Cuenca, A.	PDF	N/A	singIST: an integrative method for comparative single-cell trancriptomics between disease models and humans
Unicore通过结构核心基因实现了可扩展且准确的系统发育重建。	Kim, D.	PDF	N/A	Unicore enables scalable and accurate phylogenetic reconstruction with structural core genes
一种桥联增强型荧光染料的调色板	Zhang, J.	PDF	N/A	A Palette of Bridged Bicycle-Strengthened Fluorophores
细胞突触和扩散运输在形态发生素梯度建立中的作用	Stotsky, J.	PDF	N/A	The Role of Cytonemes and Diffusive Transport in the Establishment of Morphogen Gradients
保持GABAA受体关闭所需的单个主链氢键	Borghese, C. M.	PDF	N/A	A single main-chain hydrogen bond required to keep GABAA receptors closed
利用埃精度冷冻光镜解析PIEZO1的结构构象	Mazal, H.	PDF	N/A	Cryogenic light microscopy with Angstrom precision deciphers structural conformations of PIEZO1
隐式建模构象景观和序列可以用于评估和生成稳定的蛋白质	Cho, Y.	PDF	N/A	Implicit modeling of the conformational landscape and sequence allows scoring and generation of stable proteins
磁性粒子成像的进展：评估磁性微球和优化采集参数以实现高灵敏度细胞追踪	Flood, S. N.	PDF	N/A	Advances in magnetic particle imaging: evaluating magnetic microspheres and optimized acquisition parameters for high sensitivity cell tracking
通过直接跨膜相互作用量化模拟双层膜中的酰基链交错程度	Chaisson, E. H.	PDF	N/A	QUANTIFYING ACYL CHAIN INTERDIGITATION IN SIMULATED BILAYERS VIA DIRECT TRANSBILAYER INTERACTIONS
细胞色素“纳米线”在物理上被限制在亚皮安电流范围内，这足以满足细胞呼吸的需求。	Guberman-Pfeffer, M. J.	PDF	N/A	Cytochrome 'Nanowires' are Physically Limited to Sub-Picoamp Currents that Suffice for Cellular Respiration
抗血管生成肽VIAN-c4551通过降低肺血管通透性，在小鼠中抑制了肺黑色素瘤的转移。	Perez, A. L.	PDF	N/A	The antiangiogenic peptide VIAN-c4551 inhibits lung melanoma metastasis in mice by reducing pulmonary vascular permeability
联合抑制SHP2可克服高级别胶质瘤中由BRAF V600E驱动的对1型BRAF抑制剂的适应性抗药性	Ayanlaja, A. A.	PDF	N/A	Combined inhibition of SHP2 overcomes adaptive resistance to type 1 BRAF inhibitors in BRAF V600E-driven high-grade glioma
Parp7产生一种ADP-核糖基降解子，控制雄激素信号的负反馈。	Wierbilowicz, K.	PDF	N/A	Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling
一种用于物种无关整合癌细胞状态的深度学习工具	Rub, J.	PDF	N/A	A deep-learning tool for species-agnostic integration of cancer cell states
NHE1交换子在铜(II)配合物及菲咯啉衍生物的抗癌效应中的作用	Munoz Garzon, K. S.	PDF	N/A	Role of the NHE1 exchanger in the antitumor effects of copper(II) complexes and phenanthroline derivatives
翻译启动代表了急性髓性白血病细胞的一个脆弱点，可以与BCL-2抑制剂联合靶向。	Lee, Y. S.	PDF	N/A	Translation Initiation Represents an Acute Myeloid Leukemia Cell Vulnerability That Can Be Co-Targeted With BCL-2 Inhibition
LINC00599通过与G3BP1和MYH9发生液-液相分离（LLPS）促进肺动脉高压	Wang, Y.	PDF	N/A	LINC00599 Promotes Pulmonary Hypertension via LLPS with G3BP1 and MYH9
蛋白质聚集捕获辅助的硫醇氧化还原蛋白质组学分析	Martinez-Val, A.	PDF	N/A	Protein aggregation capture assisted profiling of the thiol redox proteome
肠道微生物群介导的药物代谢的计算分析	Chum, S.	PDF	N/A	Computational Analysis of the Gut Microbiota-Mediated Drug Metabolism
通过单细胞RNA测序确定抗TCR单克隆抗体的基因组特异性	Magill, I.	PDF	N/A	Genomic Specificity of Anti-TCR mAbs determined by single-cell RNAseq
临床CAR-T的磷酸酪氨酸信号分析揭示了与治疗效果相关的持续信号传导	Yao, B.	PDF	N/A	Phosphotyrosine Signal Profiling of Clinical CAR-T Reveals Tonic Signaling Associated with Therapeutic Efficacy
髓源性抑制细胞减轻牙周疾病的炎症	Naqvi, R.	PDF	N/A	Myeloid-derived Suppressor Cells Mitigate Inflammation in Periodontal Disease
tRNA修饰酶MnmE和MnmG对于恶性疟原虫的顶质体维持是必不可少的。	Elahi, R.	PDF	N/A	tRNA modifying enzymes MnmE and MnmG are essential for Plasmodium falciparum apicoplast maintenance
与截短型肌联蛋白（ttn.2）变异相关的心肌和骨骼肌功能障碍的部位依赖性差异	Hinits, Y.	PDF	N/A	Location-Dependent Differences in Cardiac and Skeletal Muscle Dysfunction Associated With Truncating Titin (ttn.2) Variants
顺铂诱导的肾损伤中的IQGAP1-Claudin细胞连接轴	Barudi, Y.	PDF	N/A	The IQGAP1-Claudin Cell Junction Axis in Cisplatin-induced Kidney Damage
探究空间能力多个领域对STEM教育成果的具体预测能力	Zhou, Q.	PDF	N/A	Exploring the specific predictive ability of multiple domains of spatial ability on STEM educational outcomes
对数千种鸟类物种的骨骼特征进行测量	Weeks, B. C.	PDF	N/A	Skeletal trait measurements for thousands of bird species
多聚谷氨酰胺扩展引发的雄激素受体动态错误折叠	Heling, L. W. H. J.	PDF	N/A	Polyglutamine expansion induced dynamic misfolding of Androgen Receptor
长期定殖动态：益生菌Aliivibrio spp.在大西洋鲑鱼（Salmo salar）体内的定殖情况，经浸泡处理后	Steen Dobloug, M.	PDF	N/A	Long-Term Colonization Dynamics of Probiotic Aliivibrio spp. in Atlantic Salmon (Salmo salar) Following Bath Administration
短跑间歇运动会破坏线粒体超微结构，从而在人体中引发一种独特的线粒体应激反应和重塑过程。	Botella, J.	PDF	N/A	Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in humans
# BioRxiv 2024-12-21 Papers

标题	作者	PDF链接	代码仓库	Title
男性与女性特异性GWAS结果之间的一致性有助于揭示复杂性状的潜在遗传结构。	Miller, A. K.	PDF	N/A	Concordance between male- and female-specific GWAS results helps define underlying genetic architecture of complex traits
单粒子追踪揭示了PIEZO1的异质性扩散	Ly, A. T.	PDF	N/A	Single-particle tracking reveals heterogeneous PIEZO1 diffusion
一个基于细胞外基质模型的简单框架	Metzcar, J.	PDF	N/A	A simple framework for agent-based modeling with extracellular matrix
GraphComm：一种基于图的深度学习方法，用于预测单细胞RNAseq数据中的细胞间通信	So, E.	PDF	N/A	GraphComm: A Graph-based Deep Learning Method to Predict Cell-Cell Communication in single-cell RNAseq data
人类问题解决中的自适应规划深度	Eluchans, M.	PDF	N/A	Adaptive planning depth in human problem solving
空间分岔：新皮层中功能模块化的出现	Wang, X.-J.	PDF	N/A	Bifurcation in space: Emergence of function modularity in the neocortex
Eclipse：一个用于对齐两个或更多非靶向LC-MS代谢组学数据集的Python包	Hitchcock, D. S.	PDF	N/A	Eclipse: A Python package for alignment of two or more nontargeted LC-MS metabolomics datasets
在帕金森病小鼠模型中，刺激A13区域后运动功能的恢复	Kim, L. H.	PDF	N/A	Restoration of locomotor function following stimulation of the A13 region in Parkinson's mouse models
超越种族、民族和血统的基因组队列动态聚类	Mohsen, H.	PDF	N/A	Dynamic clustering of genomics cohorts beyond race, ethnicity--and ancestry
使用FibrilPaint来测定Tau淀粉样蛋白在液体中的长度	Aragones Pedrola, J.	PDF	N/A	FibrilPaint to determine the length of Tau amyloids in fluids
从有限经验原则中涌现的动态规律与临界点	Cobo-Lopez, S.	PDF	N/A	Emerging dynamic regimes and tipping points from finite empirical principles
使用双层连续模型预测蛋白质在不同膜成分中的曲率感应	Fu, Y.	PDF	N/A	Predicting protein curvature sensing across membrane compositions with a bilayer continuum model
更易解释的多组学调控网络，用于表征表型	Aguerralde-Martin, M.	PDF	N/A	MORE interpretable multi-omic regulatory networks to characterize phenotypes
对经过治疗的乳糜泻患者微生物组进行高分辨率分析，揭示了菌株水平的变异。	Slager, J.	PDF	N/A	High-resolution analysis of the treated coeliac disease microbiome reveals strain-level variation
二聚体R25CPTH(1-34)在体外激活甲状旁腺激素-1受体，并刺激骨质疏松雌性小鼠的骨形成。	Noh, M.	PDF	N/A	Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice
使用蛋白质组范围的稳定性分析发现RNA-蛋白质分子钳	Goldstein, S. I.	PDF	N/A	Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays
基于知识图谱的思维：一种用于泛癌问题解答的增强型LLMs框架	Feng, Y.	PDF	N/A	Knowledge Graph-based Thought: a knowledge graph enhanced LLMs framework for pan-cancer question answering
在花旗松、杰克松及其杂种中，对真菌病原菌松材线虫（Dothistroma septosporum）响应的遗传结构	Lu, M.	PDF	N/A	Genetic architecture underlying response to the fungal pathogen Dothistroma septosporum in lodgepole pine, jack pine, and their hybrids
为原始的一型功能反应辩护：同时捕食多种猎物对频率和种群动态的影响	Novak, M.	PDF	N/A	In defense of the original Type I functional response: The frequency and population-dynamic effects of feeding on multiple prey at a time
PhyloFunc：作为元蛋白质组数据分析中新生态指标的基于系统发育的功能距离	Wang, L.	PDF	N/A	PhyloFunc: Phylogeny-informed Functional Distance as a New Ecological Metric for Metaproteomic Data Analysis
人类左心室环状RNA-微小RNA-信使RNA网络分析揭示了在缺血条件下circNPHP1具有新的促血管生成作用	Anwar, M.	PDF	N/A	Human left ventricle circRNA-miRNA-mRNA network analyses reveals a novel proangiogenic role for circNPHP1 under ischemic conditions
使用深度学习和溶液散射预测RNA结构和动力学	Patt, E.	PDF	N/A	Predicting RNA Structure and Dynamics with Deep Learning and Solution Scattering
通过碱基堆积相互作用调节DNA四面体的稳定性	Punnoose, J. A.	PDF	N/A	Tuning the stability of DNA tetrahedra with base-stacking interactions
使用荧光寿命测量枯草芽孢杆菌膜电位值的方法研究	Roy, D.	PDF	N/A	Towards optical measurements of membrane potential values in Bacillus subtilis using fluorescence lifetime
EnVhog：通过大量HMM配置文件对地球上病毒蛋白家族的扩展视图。	Bucio, R. E. P.	PDF	N/A	EnVhog: an extended view of the viral protein families on Earth through a vast collection of HMM profiles.
借助3D-SOCS技术窥探野生鸣禽的世界：同步视频捕捉与姿态估算	Chimento, M.	PDF	N/A	Peering into the world of wild passerines with 3D-SOCS: synchronized video capture and posture estimation
C5aR1抑制减轻了颅脑放射引起的认知功能下降。	Krattli, R. P.	PDF	N/A	C5aR1 inhibition alleviates cranial radiation-induced cognitive decline
对检测到的病毒在Peromyscus maniculatus物种复合体（啮齿目：仓鼠科）中的分布和流行情况的系统综述	Finkbeiner, A.	PDF	N/A	A Systematic Review of the Distribution and Prevalence of Viruses Detected in the Peromyscus maniculatus Species Complex (Rodentia: Cricetidae)
钠负荷正常血压小鼠的血管重塑存在性别相关差异	Viegas, K. A. d. S.	PDF	N/A	Sex-related differences in vascular remodeling of sodium overloaded normotensive mice
从组织学到人类杏仁核的宏观功能	Auer, H.	PDF	N/A	From histology to macroscale function in the human amygdala
小鼠运动技能学习能力的发展时间进程	Kim, T.	PDF	N/A	Developmental timecourse of aptitude for motor skill learning in mouse
一种整合基因组和Tn-Seq数据以识别多种细菌物种中常见体内适应性机制的新方法	Fouts, D. E.	PDF	N/A	A novel method for integrating genomic and Tn-Seq data to identify common in vivo fitness mechanisms across multiple bacterial species
STAMBPL1通过与FOXO1相互作用激活GRHL3/HIF1A/VEGFA轴，从而促进三阴性乳腺癌中的血管生成。	Fang, H.	PDF	N/A	STAMBPL1 activates the GRHL3/HIF1A/VEGFA axis through interaction with FOXO1 to promote angiogenesis in triple-negative breast cancer
机械负荷和激素变化对容量超载期间离心肥大的贡献：基于逻辑网络模型的贝叶斯分析。	Bracamonte, J. H.	PDF	N/A	Contributions of mechanical loading and hormonal changes to eccentric hypertrophy during volume overload: a Bayesian analysis using logic-based network models.
为什么端粒的长度是这样的？来自系统发育比较分析的见解	Benson, D. M.	PDF	N/A	Why are telomeres the length that they are? Insight from a phylogenetic comparative analysis
在破伤风毒素癫痫模型中减少的突触异质性：来自计算建模的见解	Zarei Eskikand, P.	PDF	N/A	Reduced Synaptic Heterogeneity in a Tetanus ToxinModel of Epilepsy: Insights from ComputationalModeling
神经肽依赖的尖峰时间精确性和昼夜节律输出神经元的可塑性	Chong, B.	PDF	N/A	Neuropeptide-dependent spike time precision and plasticity in circadian output neurons
大数据，小偏差：协调基于扩散MRI的结构连接体以减轻数据整合中的站点相关偏差	Shen, R. S.	PDF	N/A	Big Data, Small Bias: Harmonizing Diffusion MRI-Based Structural Connectomes to Mitigate Site-Related Bias in Data Integration
大鼠从空间距离到社交距离的信息传递：对后顶叶皮层在空间-社交整合中作用的启示	Wise, T. B.	PDF	N/A	Information transfer from spatial to social distance in rats: implications for the role of the posterior parietal cortex in spatial-social integration
酮生成通过超越整体脂肪氧化率的机制，保护机体免受MASLD-MASH（即多器官脂肪性肝病-代谢相关脂肪性肝病）进展的影响。	Queathem, E. D.	PDF	N/A	Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate
双面蛋白质纳米材料计算设计	Rankovic, S.	PDF	N/A	Computational design of bifaceted protein nanomaterials
通过细胞周期实现核组织的三维记忆	Fujishiro, S.	PDF	N/A	Three-dimensional memory of nuclear organization through cell cycles
G-四链体配体RHPS4通过阻断电离辐射诱导的线粒体质量和活性的增加，削弱了细胞的辐射抗性。	Tricot, S.	PDF	N/A	G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation.
混合长度基因组测序（blend-seq）：结合短读长与低覆盖率长读长以最大化变异发现	Magner, R.	PDF	N/A	Blended Length Genome Sequencing (blend-seq): Combining Short Reads with Low-Coverage Long Reads to Maximize Variant Discovery
AlphaFold 对整个基因组的预测概览	Cazals, F.	PDF	N/A	AlphaFold predictions on whole genomes at a glance
评估人类非编码RNA符号的鲁棒性	Prasetyo, N. K.	PDF	N/A	Assessing the robustness of human ncRNA notations
一种新型HLA II类抗原呈递预测算法，揭示了与KRAS G12C特异性相关的免疫原性CD4表位	Sprague, D.	PDF	N/A	A novel HLA Class II presentation prediction algorithm deciphers immunogenic CD4 epitopes specific to KRAS G12C
细胞优先调节细胞质量密度	Fu, J.	PDF	N/A	Cells Prioritize the Regulation of Cell Mass Density
OrthoHMM：利用隐马尔可夫模型改进直系同源群组的推断	Steenwyk, J. L.	PDF	N/A	OrthoHMM: Improved Inference of Ortholog Groups using Hidden Markov Models
恢复阿尔茨海默病中的振荡动力学：一种关于血清素类致幻剂效应的层级全脑模型	Gendra, J. C.	PDF	N/A	Restoring Oscillatory Dynamics in Alzheimer's Disease: A Laminar Whole-Brain Model of Serotonergic Psychedelic Effects
牛子宫内膜类器官：研究哺乳动物胚胎与母体相互作用的新工具	Edge, J. C.	PDF	N/A	Bovine endometrial organoids: A new tool to study conceptus-maternal interactions in mammals
谁说的？用空间音频和360度视频解读复杂的珊瑚礁声景	Dantzker, M. S.	PDF	N/A	Who said that? Deciphering Complex Coral Reef Soundscapes with Spatial Audio and 360 Degree Video
一个整合了低氧、机械感应和TGF-β信号传导的布尔网络模型，揭示了表型可塑性和突变在肿瘤转移中的作用。	Greene, G.	PDF	N/A	A Boolean network model of hypoxia, mechanosensing and TGF-β signaling captures the role of phenotypic plasticity and mutations in tumor metastasis
一种用于预测蛋白质内在无序区域相互作用的深度学习方法	Majila, K.	PDF	N/A	A deep learning method for predicting interactions for intrinsically disordered regions of proteins
一个用于自主AI驱动药物发现的框架	Selinger, D. W.	PDF	N/A	A Framework for Autonomous AI-Driven Drug Discovery
鉴定PTGR2抑制剂作为糖尿病和肥胖的新疗法	Chang, Y.-C.	PDF	N/A	Identification of PTGR2 inhibitors as a new therapy for diabetes and obesity
多模态单细胞数据推断基因调控网络方法的比较与评估	Badia-i-Mompel, P.	PDF	N/A	Comparison and evaluation of methods to infer gene regulatory networks from multimodal single-cell data
协调的脊髓运动神经网络动态产生于特定细胞类型的连接模式	Wandler, F. D.	PDF	N/A	Coordinated spinal locomotor network dynamics emerge from cell-type-specific connectivity patterns
内在功能连接描绘了跨模态语言功能。	Salvo, J. J.	PDF	N/A	Intrinsic functional connectivity delineates transmodal language functions
祖先序列重建对位点间进化异质性和上位性的稳健性	Muniz-Trejo, R.	PDF	N/A	Robustness of ancestral sequence reconstruction to among-site evolutionary heterogeneity and epistasis
MCL-1调控少突胶质细胞发育过程中的细胞转变	Gil, M.	PDF	N/A	MCL-1 regulates cellular transitions during oligodendrocyte development
人类几丁质三糖酶-1催化装置的机制及其通过首创的OATD-01抑制剂的双重失活模式。	Niedzialek, D.	PDF	N/A	Mechanism of catalytic apparatus of human chitotriosidase-1 and its dual inactivation mode by the first-in-class OATD-01 inhibitor.
I2SIM：通过图像干扰与空间频谱优化提升高保真各向同性超分辨率	He, E.	PDF	N/A	I2SIM: Boosting High-Fidelity Isotropic Super-Resolution with Image Interference and Spatial-Spectrum Optimization
气候驱动了西加那利群岛蜥蜴（Gallotia galloti）长期的地貌变化和短期的快速进化。	Gilbert, E.	PDF	N/A	Climate drives long-term landscape and rapid short-term promoter evolution in the Western Canaries lizard, Gallotia galloti
25-羟基胆固醇有效抑制日本脑炎病毒在Vero细胞中的感染。	Archana, K.	PDF	N/A	25 Hydroxy Cholesterol Effectively Inhibits Japanese Encephalitis Virus Infection in Vero Cells
基于电子密度的有效且可靠的从头分子设计和先导优化，采用ED2Mol方法	Li, M.	PDF	N/A	Electron-density informed effective and reliable de novo molecular design and lead optimization with ED2Mol
通过条件复杂度约束表型转变概率	Dingle, K.	PDF	N/A	Bounding phenotype transition probabilities via conditional complexity
G-四链体通过重塑能量景观来催化蛋白质折叠	Huang, Z.	PDF	N/A	G-quadruplexes catalyze protein folding by reshaping the energetic landscape
杨树木材纤维G层中类似束蛋白的阿拉伯半乳聚糖蛋白的免疫定位	Takeuchi, M. -	PDF	N/A	Immunolocalization of fasciclin-like arabinogalactan proteins in the G-layers of poplar tension wood fibers
德国北部牛场寄生虫对苯并咪唑和聚醚类药物的抗药性	Ehnert, P.	PDF	N/A	Anthelmintic resistance against benzimidazoles and macrocyclic lactones in strongyle populations on cattle farms in northern Germany
细菌表面上的血红素结合DNA结构促进了胞外电子传递。	Ajunwa, O. M.	PDF	N/A	Hemin-binding DNA structures on the surface of bacteria promote extracellular electron transfer
巴西卡廷加干旱地区的土壤微生物群	Tacca, L. M. A. d.	PDF	N/A	The Soil Microbiome of the Caatinga Drylands in Brazil
利用禽致病性大肠杆菌（APEC）系统发育群的基因组规模代谢重建来鉴定谱系特异性代谢途径	Long, H.	PDF	N/A	Use of Genome Scale Metabolic Reconstructions of Avian Pathogenic Escherichia coli (APEC) phylogroups for the identification of lineage-specific metabolic pathways
通过miRNA靶向CMP-唾液酸合酶来描绘唾液酸化的调控格局	Jame-Chenarboo, F.	PDF	N/A	Profiling the Regulatory Landscape of Sialylation through miRNA Targeting of CMP- Sialic Acid Synthetase
城市适应性野生动物中人畜共患病毒的风险评估	Wei, X.	PDF	N/A	Risk assessment of zoonotic viruses in urban-adapted wildlife
两个虾的故事 - 两种共域虾类物种的物种形成与种群动态，来自热液喷口	Methou, P.	PDF	N/A	A tale of two shrimps - Speciation and demography of two sympatric shrimp species from hydrothermal vents
两个虾的故事——来自热液喷口的两种同域虾种的物种形成与种群动态	Methou, P.	PDF	N/A	A tale of two shrimps - Speciation and demography of two sympatric shrimp species from hydrothermal vents
探索褐藻中的减数分裂：模式褐藻Ectocarpus中的减数分裂轴蛋白	Kane, E. I.	PDF	N/A	Exploring Meiosis in Brown Algae: Meiotic Axis Proteins in the model brown alga Ectocarpus
热力学稳定性调控伴侣蛋白介导的α-突触核蛋白纤维解聚	Fricke, C.	PDF	N/A	Thermodynamic Stability Modulates Chaperone-Mediated Disaggregation of α-Synuclein Fibrils
基于连续滴定的方法用于非共价相互作用的快速溶液内分析	Willmer, P.	PDF	N/A	Continuous Titration Based Method For Rapid In-solution Analysis Of Non-covalent Interactions
环核苷酸门控CNGA1离子通道中阳离子渗透与孔电压敏感性的原子机制	Liu, H.	PDF	N/A	Atomistic Mechanism of Cation Permeation and Pore Voltage Sensitivity in Cyclic Nucleotide-Gated CNGA1 Ion Channel
通过基因组挖掘在湿链霉菌中发现并合成Nyuzenamides D和E	Lum, K. Y.	PDF	N/A	Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in Streptomyces hygroscopicus
甘油体磷酸烯醇丙酮酸羧激酶CRISPR/Cas9缺失及其在克氏锥虫后循环发生和哺乳动物宿主感染性中的作用	Vieira, C. S. D.	PDF	N/A	Glycosomal phosphoenolpyruvate carboxykinase CRISPR/Cas9-deletion and its role in Trypanosoma cruzi metacyclogenesis and infectivity in mammalian host
牙龈卟啉单胞菌脂多糖A 1-磷酸酶LpxE具有独特的特性，其活性需要一个功能性的IX型分泌系统的支持。	Wang, S.	PDF	N/A	The Porphyromonas gingivalis lipid A 1-phosphatase LpxE has unique features and requires a functional type IX secretion system for its activity
系统性功能评估宿主中抗噬菌体系统的本征功能	David, E.	PDF	N/A	Systematic functional assessment of antiphage systems in their native host
鼠疫耶尔森菌能主动抑制人中性粒细胞产生胞外囊泡。	Sheneman, K. R.	PDF	N/A	Yersinia pestis actively inhibits the production of extracellular vesicles by human neutrophils
cryoTIGER：基于深度学习的倾斜插值生成器，用于增强冷冻电子断层扫描中的重建	Majtner, T.	PDF	N/A	cryoTIGER: Deep-Learning Based Tilt Interpolation Generator for Enhanced Reconstruction in Cryo Electron Tomography
重组对恶性疟原虫疟疾多药抗性进化的影响	Tran, K. T.	PDF	N/A	Effects of recombination on multi-drug resistance evolution in Plasmodium falciparum malaria
受神经普通微分方程启发的动力学模型参数化方法	Lent, P. v.	PDF	N/A	Neural Ordinary Differential Equations Inspired Parameterization of Kinetic Models
激素调控的Sertoli细胞中mRNA在核糖体上的分布动态	Leray, X.	PDF	N/A	Hormone-regulated dynamics of mRNA distribution on ribosomes in Sertoli cells
视网膜拓扑映射数据允许在不同数据集之间进行准确的参与者匹配。	Schwarzkopf, D. S.	PDF	N/A	Retinotopic mapping data permit accurate matching of participants across different datasets
并非所有跨模态反应都可以用面部运动来解释。	Olsen, T. R.	PDF	N/A	Not all cross-modal responses are explained by face movements
皮层相似网络的遗传结构	Sebenius, I.	PDF	N/A	The genetic architecture of cortical similarity networks
转录组破坏和功能性低活性在DYT-SGCE MGE模式抑制性神经元中	Li, Z.	PDF	N/A	Transcriptomic disruption and functional hypoactivity in DYT-SGCE MGE-patterned inhibitory neurons
限时进食是否伴随酮症以一种组织特异性的方式影响老年大鼠代谢相关基因的表达。	Ding, S.	PDF	N/A	Time restricted feeding with or without ketosis influences metabolism-related gene expression in a tissue-specific manner in aged rats
声音引发的神经可塑性变化区分了耳鸣与非耳鸣小鼠	Fabrizio-Stover, E. M.	PDF	N/A	Sound-Evoked Plasticity Differentiates Tinnitus from Non-Tinnitus Mice
时间上重叠的机制在体内使克隆B细胞的反应多样化。	Skinner, O. P.	PDF	N/A	Temporally overlapping mechanisms diversify clonal B cell responses in vivo.
异源免疫策略开发出针对BK病毒具有广泛反应性的人源单克隆抗体	Duty, J. A.	PDF	N/A	Heterologous immunization strategy developed broadly reactive human monoclonal antibodies against the BK virus
氟喹诺酮类药物治疗引起的多样表型和突变谱	Mohiuddin, S. G.	PDF	N/A	The Diverse Phenotypic and Mutational Landscape Induced by Fluoroquinolone Treatment
创新的肉碱喂养大鼠模型揭示了白藜芦醇丁酸酯在降低TMAO和心血管风险中的多重机制作用	Hou, C.-Y.	PDF	N/A	Innovative Carnitine-Fed Rats Model Reveals Resveratrol Butyrate Ester's Multimechanistic Role in Reducing TMAO and Cardiovascular Risk
线粒体损伤会引发治疗诱导的衰老。	Baltira, C.	PDF	N/A	Mitochondrial damage triggers therapy-induced senescence
一种用于评估E3连接酶在靶向蛋白质降解中应用的细胞内方法。	Zheng, Y.	PDF	N/A	An in-cell approach to evaluate E3 ligases for use in targeted protein degradation.
一份关于西北欧节肢动物生活史和生态特征的深入数据集	Logghe, G.	PDF	N/A	An in-depth dataset of northwestern European arthropod life histories and ecological traits
加利福尼亚特有橡树对气候变暖的不适应反应，可通过其生长和存活的年际变化进行预览。	Goetz, A. R. B.	PDF	N/A	Maladaptive response of an endemic California oak to climatic warming is previewed by interannual variation in growth and survival
破译硫内酰胺化机制在硫内酰胺霉素生物合成中的作用	Guo, J.	PDF	N/A	Deciphering the thiolactonization mechanism in thiolactomycin biosynthesis
基因先锋：一个全面的Python包，用于识别癌症中的关键基因和模块	Taheri, G.	PDF	N/A	GenePioneer: A Comprehensive Python Package for Identification of Essential Genes and Modules in Cancer
蛋白质序列内在无序特征的概率注释	Malhis, N.	PDF	N/A	Probabilistic Annotations of Protein Sequences for Intrinsically Disordered Features
力传递是机械细胞竞争的主调控因子。	Schoenit, A.	PDF	N/A	Force transmission is a master regulator of mechanical cell competition
最后手段抗生素达托霉素展示了两种独立的抗菌作用机制。	Buttress, J. A.	PDF	N/A	The last resort antibiotic daptomycin exhibits two independent antibacterial mechanisms of action
发育延迟确保了局部凋亡诱导下整体组织大小的稳定性。	Staneva, R.	PDF	N/A	Developmental delay ensures global tissue size robustness upon local induction of apoptosis
在相对简单的生命周期中，基因重复和非随机基因组织的减少特征塑造了阶段特异性基因表达模式	DuBose, J. G.	PDF	N/A	Reduced signatures of gene duplication and non-random gene organization in shaping stage-specific patterns of gene expression across a relatively simple life cycle
蛋白质组规模定量分析驱动无序蛋白质凝聚体形成的相互作用	Norrild, R. K.	PDF	N/A	Proteome-scale quantification of the interactions driving condensate formation of intrinsically disordered proteins
Syn-tasiR-VIGS：基于最小前体衍生的合成转录活性小干扰RNA在植物中实现病毒介导的靶向RNAi	Cisneros, A. E.	PDF	N/A	Syn-tasiR-VIGS: Virus-Based Targeted RNAi in Plants By Synthetic Trans Acting Small Interfering RNAs Derived from Minimal Precursors
联合模型揭示了人类皮层下结构对选择和学习行为的基础作用	Miletic, S.	PDF	N/A	Joint models reveal human subcortical underpinnings of choice and learning behaviour
基于代理的枯草芽孢杆菌生物膜代谢信号振荡模型	Mulder, O.	PDF	N/A	An Agent-Based Model of Metabolic Signaling Oscillations in Bacillus subtilis Biofilms
盘星类（Stentor pyriformis）是一种巨大的细胞，其细胞生物学和基因组的特点在于，它将共生藻类嵌入到微管网络中。	Boudreau, v.	PDF	N/A	The cell biology and genome of Stentor pyriformis, a giant cell that embeds symbiotic algae in a microtubule meshwork
吸引本地传粉者到城市绿地	Mata, L.	PDF	N/A	Attracting indigenous pollinators to urban greenspaces
泛基因组小麦品种种子性状的多组学可塑性	Bose, U.	PDF	N/A	Multiomics plasticity in seed traits of pan-genome wheat cultivars
基于单倍型的进化历史揭示了大麦的驯化过程	Guo, Y.	PDF	N/A	A haplotype-based evolutionary history of barley domestication
一个远程抑制系统调控寄生植物吸器数量	Kokla, A.	PDF	N/A	A long-distance inhibitory system regulates haustoria numbers in parasitic plants
一种在伽蓝菜属植物中用于研究生物节律调控景天酸代谢（CAM）的分子元素的工具：荧光素酶报告基因成像技术	Pritchard, J. H.	PDF	N/A	A promoter::luciferase reporter gene imaging toolkit in Kalanchoë laxiflora reveals molecular elements responsible for the circadian regulation of Crassulacean acid metabolism (CAM)
延伸的下胚轴5调控拟南芥中光介导的角鲨烯生物合成和发育	Pathak, P. K.	PDF	N/A	ELONGATED HYPOCOTYL 5 regulates light-mediated squalene biosynthesis and development in Arabidopsis thaliana
空间转录组学揭示了在细胞分辨率下发育中的小麦花序中的表达梯度	Long, K. A.	PDF	N/A	Spatial Transcriptomics Reveals Expression Gradients in Developing Wheat Inflorescences at Cellular Resolution
辅酶M：一种作为农业生物刺激素的古菌抗氧化剂	Brown, J. H.	PDF	N/A	Coenzyme M: An Archaeal Antioxidant as an Agricultural Biostimulant
温暖的环境温度会改变细胞命运，从而减少拟南芥的气孔生成。	Saiz-Perez, J.	PDF	N/A	Warm temperature modifies cell fates to reduce stomata production in Arabidopsis
TUTase URT1调控种子转录组及其初级休眠	Peter, J.	PDF	N/A	The TUTase URT1 regulates the transcriptome of seeds and their primary dormancy
欧洲白蜡树更新后的长读长基因组揭示了MADS-box基因在抵御白蜡树枯萎病耐受机制中的重要性	Franco Ortega, S.	PDF	N/A	Fraxinus excelsior updated long-read genome reveals the importance of MADS-box genes in tolerance mechanisms against ash dieback
有机肥与无机肥配合施用对高丹草土壤及产量的影响	Yi, Z.	PDF	N/A	Effects of combined application of organic fertilizer and inorganic fertilizer on soil and yield of Gaodan grass
人工生态系统中植物的高光谱分割	Zwart, P. H.	PDF	N/A	Hyperspectral Segmentation of Plants in Fabricated Ecosystems
利用定量蛋白质组学技术研究Humalite施用对田间种植小麦（Triticum aestivum L.）分子影响的研究	Grubb, L. E.	PDF	N/A	Defining the molecular impacts of Humalite application on field-grown wheat (Triticum aestivum L.) using quantitative proteomics
地质和气候因素在华盛顿喀斯喀特山脉的峰峦之间驱动了高山植物组成的变异。	Ertsgaard, E. W.	PDF	N/A	Geology and climate drive alpine plant compositional variation among peaks in the Cascade Range of Washington
类似炎症的环境限制了铜绿假单胞菌群体感应的丧失	Fu, T.	PDF	N/A	Inflammation-like environments limit the loss of quorum sensing in Pseudomonas aeruginosa
应用GRF-GIF嵌合体增强番茄基因组编辑中的植物再生	Swinnen, G.	PDF	N/A	Application of a GRF-GIF chimera enhances plant regeneration for genome editing in tomato
被子植物种子的生命周期遵循一个发育的反向沙漏模型。	Sami, A. A.	PDF	N/A	The angiosperm seed life cycle follows a developmental reverse hourglass
酵母中对Killer Toxin K28的抗性依赖于COG复合体介导的防御因子Ktd1的运输。	Laidlaw, K.	PDF	N/A	Killer Toxin K28 resistance in yeast relies on COG complex mediated trafficking of the defence factor Ktd1
一种在植物中高效产生结构变异的方法	Bechen, L. L.	PDF	N/A	A simple method to efficiently generate structural variation in plants
揭示三种十字花科作物中独特的代谢组和转录组特征	Zhang, L.	PDF	N/A	Unveiling unique metabolomic and transcriptomic profiles in three Brassicaceae crops
云杉杂交种表现出比其生态上差异较大的亲本物种更优越的累积生长量和对气候异常的中间响应。	Reed-Metayer, E.	PDF	N/A	Spruce hybrids show superior cumulative growth and intermediate response to climate anomalies, as compared to their ecologically divergent parental species
通过PAP和DXO1调控拟南芥中共翻译mRNA降解的机制	Carpentier, M.-C.	PDF	N/A	Regulation of co-translational mRNA decay by PAP and DXO1 in Arabidopsis
热应激促使再生扁虫Macrostomum lignano中的LTR逆转录转座子转录。	Ustyantsev, K.	PDF	N/A	Heat stress drives transcription of LTR retrotransposons in the regenerative flatworm Macrostomum lignano
分阶段的基因组组装和泛基因组图谱展示了日本和沙特阿拉伯人群的基因组特征。	Kulmanov, M.	PDF	N/A	Phased genome assemblies and pangenome graphs of human populations of Japan and Saudi Arabia
一项针对人类前额叶皮层体细胞嵌合现象的多平台个性化评估	Zhou, W.	PDF	N/A	A personalized multi-platform assessment of somatic mosaicism in the human frontal cortex
肠道微生物群促进帕金森病小鼠模型大脑中的线粒体呼吸作用	Morais, L. H.	PDF	N/A	The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson's disease mouse model
对延髓和脑桥网络中阿片类药物引起呼吸抑制潜在机制的建模洞察	Olsen, W. L.	PDF	N/A	Modeling Insights into Potential Mechanisms of Opioid-Induced Respiratory Depression within Medullary and Pontine Networks
标准化方法用于在实验室环境下饲养蛾类幼虫——烟草天蛾（Manduca sexta）。	Spencer, E. K.	PDF	N/A	Standardized methods for rearing a moth larva, Manduca sexta, in a laboratory setting
Septin细胞骨架将Cdc42 GAP Rga4排除在生长部位之外，以促进分裂酵母的双极性。	McDuffie, J.	PDF	N/A	The Septin Cytoskeleton excludes the Cdc42 GAP Rga4 from growing sites to promote bipolarity in fission yeast
LC3在自噬体上形成功能性纳米团簇	Fatihi, S.	PDF	N/A	LC3 forms functional nanocluster on autophagosome
共存液相界面间的传输动力学	Hubatsch, L.	PDF	N/A	Transport kinetics across interfaces between coexisting liquid phases
利用深度学习设计针对细胞内感染的多模态抗生素	Cesaro, A.	PDF	N/A	Design of multimodal antibiotics against intracellular infections using deep learning
通过LoxPsym介导的酵母上游激活序列重排实现体内通路优化	Ruehmkorff, C.	PDF	N/A	In Vivo Pathway Optimization in Yeast via LoxPsym-Mediated Shuffling of Upstream Activating Sequences
从生物学角度构建图神经网络以模拟大脑动态并推断连接性	Gupta, A.	PDF	N/A	Biologically Plausible Graph Neural Networks for Simulating Brain Dynamics and Inferring Connectivity
5岁儿童的努力控制与大脑皮质结构：来自FinnBrain出生队列研究的发现	Frantti, M.	PDF	N/A	Effortful control and cortical brain structure in 5-year-old children: findings from the FinnBrain birth cohort study
一个分子定义明确的脑回路模块，用于调节类似恐慌的防御状态	Zhao, M.	PDF	N/A	A molecularly defined brain circuit module for regulating the panic-like defensive state
人类对形状的感知会自发地发现新颖但自然的刺激的生物起源。	Dehn, K. I.	PDF	N/A	Human shape perception spontaneously discovers the biological origin of novel, but natural, stimuli
中年和老年自闭症谱系成年人的BOLD信号变异性降低	Pedrahita, S.	PDF	N/A	Decreased BOLD signal variability in middle-aged and older adults on the Autism Spectrum
大鼠皮层微观结构相似性网络的发展及其对早期生活压力的敏感性	Smith, R. L.	PDF	N/A	Development and early life stress sensitivity of the rat cortical microstructural similarity network
蛋白激酶G抑制在一种新的常染色体显性视网膜色素变性小鼠模型中，保护了光感受器的生存能力和功能。	Zhu, Y.	PDF	N/A	Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa
猴子决策参考点的神经表示	Nguyen, D.	PDF	N/A	Neuronal representation of the decisional reference point in monkeys
星形胶质细胞中Frataxin的缺乏会驱动镰状细胞病小鼠的神经认知功能障碍。	Novelli, E. M.	PDF	N/A	Frataxin deficiency in the astrocytes drives neurocognitive impairment in sickle cell disease mice
在模糊处理过程中，与前额叶皮层的连接和蓝斑活动的年龄相关增加	Dave, A.	PDF	N/A	Age-related Increase in Locus Coeruleus Activity and Connectivity with Prefrontal Cortex during Ambiguity Processing
生态证据综合中的已知未知和模型选择	Blowes, S. A.	PDF	N/A	Known unknowns and model selection in ecological evidence synthesis
生态特化与同域形态的牙齿特征变异	Jonsdottir, G. O.	PDF	N/A	Variation of tooth traits in ecologically specialized and sympatric morphs
Flashzoi：一种用于加速基因组分析的增强型Borzoi模型	Hingerl, J. C.	PDF	N/A	Flashzoi: An enhanced Borzoi model for accelerated genomic analysis
使用iconPCR进行16S文库制备可以提高数据质量和实验流程。	Patel, P.	PDF	N/A	The use of iconPCR for 16S library preparation improves data quality and workflow
一种改进的神经网络模型能够在具有挑战性的条件下进行蠕虫追踪，并提高表型筛选中的信噪比。	Weheliye, W. H.	PDF	N/A	An improved neural network model enables worm tracking in challenging conditions and increases signal-to-noise ratio in phenotypic screens
化学遗传激活内侧前额叶皮层投射至伏隔核壳部可抑制EcoHIV感染小鼠的可卡因引发复吸	Xie, Q.	PDF	N/A	Chemogenetic Activation of Medial Prefrontal Cortex Projections to the Nucleus Accumbens Shell Suppresses Cocaine-Primed Reinstatement in EcoHIV Infected Mice
应用计算蛋白质设计来设计affibodies，用于血管内皮生长因子和血小板衍生生长因子的亲和力控制递送。	Svendsen, J. E.	PDF	N/A	Applying computational protein design to engineer affibodies for affinity-controlled delivery of vascular endothelial growth factor and platelet-derived growth factor
基于牛奶光谱特征的酮病牛识别：基于Aquaphotomics原理的化学计量学建模方法	Giovinazzo, S.	PDF	N/A	Identification of ketotic cattle based on milk spectroscopic characteristics: a chemometric modelling approach built upon the principles of Aquaphotomics
遥控无线生物电子设备用于氟西汀治疗以促进猪模型中的伤口愈合	Li, H.	PDF	N/A	Remote-Controlled Wireless Bioelectronics for Fluoxetine Therapy to Promote Wound Healing in a Porcine Model
用DBCO标记金黄色葡萄球菌表面以进行点击化学介导的敏感货物沉积的新方法	Baryakova, T.	PDF	N/A	Novel approaches to label the surface of S. aureus with DBCO for click chemistry-mediated deposition of sensitive cargo
设计和验证用于猪模型中自动化伤口监测的可穿戴成像系统	HEE, W. S.	PDF	N/A	Design and Validation of a Wearable Imaging System for Automated Wound Monitoring in Porcine Model
使用TopKAT检测多重空间蛋白质组学影像中的临床相关拓扑结构	Samorodnitsky, S.	PDF	N/A	Detecting Clinically Relevant Topological Structures in Multiplexed Spatial Proteomics Imaging Using TopKAT
番茄植株中的腺毛破裂是一种超快且敏感的防御机制，用以抵御昆虫。	Popowski, J.	PDF	N/A	Glandular Trichome Rupture in Tomato Plants is an Ultra-Fast & Sensitive Defense Mechanism Against Insects
大麦病害筛选：一种用于检测Ramularia collo-cygni、Rhynchosporium graminicola和Pyrenophora teres的多重数字滴液PCR方法	Zia, R.	PDF	N/A	Barley disease screening: a multiplex digital droplet PCR approach for the detection of Ramularia collo-cygni, Rhynchosporium graminicola and Pyrenophora teres
早期催产素可挽救脆性X综合征小鼠模型中的海马突触可塑性和情景记忆	Chavez, J.	PDF	N/A	Early-life Oxytocin Rescues Hippocampal Synaptic Plasticity and Episodic Memory in a Mouse Model of Fragile X Syndrome
tDCS的神经机制：来自具有现实电场强度的活体啮齿动物模型的见解	Chen, L.	PDF	N/A	Neural Mechanisms of tDCS: Insights from an In-Vivo Rodent Model with Realistic Electric Field Strengths
中央凹视觉中的不对称性	Jenks, S. K.	PDF	N/A	Asymmetries in foveal vision
小鼠Timothy综合征模型中初级视觉皮层生理与功能的紊乱	Craddock, R.	PDF	N/A	Disruptions in Primary Visual Cortex Physiology and Function in a Mouse Model of Timothy Syndrome
dFCExpert：利用模块化和状态专家学习动态功能连接模式	Chen, T.	PDF	N/A	dFCExpert: Learning Dynamic Functional Connectivity Patterns with Modularity and State Experts
光损伤中光感受器细胞死亡机制	Bruera, M. G.	PDF	N/A	Photoreceptor cell death mechanism in light damage
高效集成编码的动力学	Ni, L.	PDF	N/A	Dynamics of efficient ensemble coding
在活体斑马鱼中，kif5Aa缺失导致的麻醉敏感性变化与线粒体运动改变有关。	Bedell, V.	PDF	N/A	In vivo changes in zebrafish anesthetic sensitivity in response to the loss of kif5Aa are associated with the alteration of mitochondrial motility
在初级视皮层（V1）超柱中动态分组进行中的活动	Zhang, R.	PDF	N/A	Dynamic Grouping of Ongoing Activity in V1 Hypercolumns
运动处理自适应循环神经网络中的能效和灵敏度优势	Mohan, V.	PDF	N/A	Energy efficiency and sensitivity benefits in a motion processing adaptive recurrent neural network
区分Peromyscus leucopus骨髓来源的巨噬细胞以表征其对伯氏疏螺旋体和脂多糖的反应	Wells, C. C.	PDF	N/A	Differentiating Peromyscus leucopus bone marrow-derived macrophages for characterization of responses to Borrelia burgdorferi and lipopolysaccharide
CD4+ T细胞为力敏感的TCR:pMHC相互作用创造了一个稳定的机械环境。	Schrangl, L.	PDF	N/A	CD4+ T-cells create a stable mechanical environment for force-sensitive TCR:pMHC interactions
急性传染性单核细胞增多症会产生持久的功能性EBNA-1抗体，这些抗体具有高度的交叉反应性，能够识别α晶体β。	Ganta, K. K.	PDF	N/A	Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha crystalline beta
人类B1类G蛋白偶联受体（GPCR）对细胞膜脂质的调节	Chao, K. W.	PDF	N/A	Human class B1 GPCR modulation by plasma membrane lipids
Enterobactin通过一种独立于二价金属转运蛋白DMT1的机制，将铁带入秀丽隐杆线虫和哺乳动物的肠道细胞。	Sewell, A. K.	PDF	N/A	Enterobactin carries iron into C. elegans and mammalian intestinal cells by a mechanism independent of divalent metal transporter DMT1
NANOG增强子的发现及其在人胚胎干细胞自我更新和分化中的关键作用	Yan, J.	PDF	N/A	Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells
海洋鱼类在生物荧光发射光谱上表现出显著的多样性。	Carr, E.	PDF	N/A	Marine fishes exhibit exceptional variation in biofluorescent emission spectra
超越社区加权平均值：量化性状分布以检测社区构建模式	Melero, Y.	PDF	N/A	Beyond community-weighted means: quantifying trait distributions for detecting community assembly patterns
主要组织相容性复合体多样性对社会性哺乳动物适应性的性别依赖性影响	Schubert, N.	PDF	N/A	Sex-dependent influence of major histocompatibility complex diversity on fitness in a social mammal
通过全基因组关联研究，鉴定出SENP7和UTF1/VENTX作为影响血液和大脑中聚集型原钙粘蛋白甲基化的新位点	Liu, Y.	PDF	N/A	Identification of SENP7 and UTF1/VENTX as new loci influencing clusteredprotocadherin methylation across blood and brain using a genome-wide associationstudy
复制压力在整个疟原虫基因组中增加了新生拷贝数变异	Brown, N. J.	PDF	N/A	Replication stress increases de novo CNVs across the malaria parasite genome
泛基因组结构变异模式反映了甘蓝型油菜的进化多样化	Afsharyan, N. P.	PDF	N/A	Pangenomic structural variant patterns reflect evolutionary diversification in Brassica napus
在奶牛中进行的基因组范围关联分析强调了与小鼠和人类生育能力以及人类健康特征重叠的基因。	Marrella, M.	PDF	N/A	Genome-wide association analyses in dairy heifers highlight genes overlapping with mouse and human fertility and human health traits
人类ORC2对表观遗传和染色体结构的调控	Su, Z.	PDF	N/A	Regulation of epigenetics and chromosome structure by human ORC2
黄素蛋白作为细胞内电子顺磁共振光谱学的天然和遗传编码自旋探针	Chauvire, T.	PDF	N/A	Flavoproteins as native and genetically encoded spin probes for in cell ESR spectroscopy
微生理学尿毒症模型揭示了血管功能障碍的生物物理增强因素	Rathod, M.	PDF	N/A	Microphysiological uremia model reveals biophysical potentiators of vascular dysfunction
通过近红外二区纳米传感器非侵入性地实时监测体内免疫细胞与肿瘤细胞的相互作用	Huang, L.	PDF	N/A	Noninvasively real-time monitoring in-vivo immune cell and tumor cell interaction by NIR-II nanosensor
细菌驱动的活性材料可促进珊瑚幼虫的定居。	Levy, N.	PDF	N/A	Bacteria-powered living materials enable coral larval settlement
从复杂陆地生境中恢复高连续性的基因组揭示了超过15,000种新的原核生物物种，并扩展了对土壤和沉积物微生物群落的特征描述。	Sereika, M.	PDF	N/A	Recovery of highly contiguous genomes from complex terrestrial habitats reveals over 15,000 novel prokaryotic species and expands characterization of soil and sediment microbial communities
在存在未知个体的情况下对个体动物进行声学识别	Huang, L.	PDF	N/A	Acoustic Recognition of Individual Animals in thePresence of Unknown Individuals
基准测试单细胞RNA测序拷贝数变异检测工具	Schmid, K. T.	PDF	N/A	Benchmarking scRNA-seq copy number variation callers
一种与量子兼容的经典连续体模型解释了细胞膜及其交联剂的力学响应。	Kim, J.	PDF	N/A	A quantum compatible classical continuum model explains mechanical responses of cell membranes and membrane crosslinkers
扩展基于氮氧自由基的顺磁探针的多样性，这些探针与非经典氨基酸结合，用于SDSL-EPR应用	Bizet, M.	PDF	N/A	Expanding the diversity of nitroxide-based paramagnetic probes conjugated to non-canonical amino acids for SDSL-EPR applications
将环境质谱成像与同一癌症组织上的空间转录组学相结合，以识别基因-代谢物相关性	Godfrey, T. M.	PDF	N/A	Integrating Ambient Mass Spectrometry Imaging and Spatial Transcriptomics on the Same Cancer Tissues to Identify Gene-Metabolite Correlations
PRLX-93936 和 BMS-214662 是细胞毒性分子胶，它们利用 TRIM21 来降解核孔蛋白。	Scemama de Gialluly, M. A.	PDF	N/A	PRLX-93936 and BMS-214662 are cytotoxic molecular glues that leverage TRIM21 to degrade nucleoporins
酮体β-羟基丁酸介导的表观遗传染色质β-羟基丁酰化保护肾脏	Mandal, J.	PDF	N/A	The ketone body β-Hydroxybutyrate mediated epigenetic chromatin β-hydroxybutyrylation protects kidneys
通过深度强化学习加速伤口愈合：一种数据驱动的最佳治疗方案	Lu, F.	PDF	N/A	Accelerating Wound Healing Through Deep Reinforcement Learning: A Data-Driven Approach to Optimal Treatment
在人类大脑中通过功能成像跨越空间尺度；在10.5特斯拉场强下的初步经验	Vizioli, L.	PDF	N/A	Spanning spatial scales with functional imaging in the human brain; initial experiences at 10.5 Tesla
熟练运动技能的自然变异性在自由活动小鼠的大脑皮层中得到了稳定的编码。	de Laittre, E. A.	PDF	N/A	The natural variability of a dexterous motor skill is stably encoded in the cortex of freely behaving mice
小鼠脑类器官模型能够模拟体内神经发育和功能，并能捕捉到与人类之间的差异。	Lancaster, M. A.	PDF	N/A	Mouse brain organoids model in vivo neurodevelopment and function and capture differences to human
LAG3标记了激活但低反应性的NK细胞。	Vasilyeva, V.	PDF	N/A	LAG3 marks activated but hyporesponsive NK cells.
在动物中，可移动元件的水平转移更多地受到系统发育相关性的促进，而非水生栖息地。	Muller, H.	PDF	N/A	Phylogenetic relatedness rather than aquatic habitat fosters horizontal transfer of transposable elements in animals
东非慈鲷V1R受体基因显著多样性中可能涉及的幽灵渗入	Taki, S.	PDF	N/A	Possible involvement of ghost introgressions in the striking diversity of V1R receptor genes in East African cichlids
基于药效团约束的新药设计与扩散桥接技术	Wang, C.	PDF	N/A	Pharmacophore-constrained de novo drug design with diffusion bridge
学习使用MSA Transformer进行系统发育的语言	Chen, R.	PDF	N/A	Learning the Language of Phylogeny with MSA Transformer
EpiAgent：单细胞表观基因组数据的基石模型	Chen, X.	PDF	N/A	EpiAgent: Foundation model for single-cell epigenomic data
通过逐步外显子定义实现协调的可变剪接决策	Kristofori, P.	PDF	N/A	Coordinated alternative splicing decisions via stepwise exon definition
基于志贺毒素的工程免疫原的冷冻电镜结构，能够引发具有治疗溶血性尿毒综合征潜力的中和抗体。	Cristofalo, A. E.	PDF	N/A	Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against Hemolytic Uremic Syndrome
一个可靶向的发展程序共同调控血管生成和免疫逃逸	Berico, P.	PDF	N/A	A targetable developmental program co-regulates angiogenesis and immune evasion
应激驱动的可遗传非遗传性药物抗性出现	Xie, J. L.	PDF	N/A	Stress-driven emergence of heritable non-genetic drug resistance
推测的细粒棘球绦虫的EGF配体和受体，对寄生虫发育至关重要。	Koike, A.	PDF	N/A	Putative EGF ligand and receptor of Echinococcus multilocularis that are critical for parasite development
现场监测和液压模型量化了未处理污水作为一条流经大城市的河流中抗药性基因的主要来源。	Sonkar, V.	PDF	N/A	Field monitoring and hydraulic modelling quantify untreated wastewater as dominant source of AMR in a small river running through a big city
定义高翻译通读终止密码子上下文	Smoljanow, D.	PDF	N/A	Defining the high-translational readthrough stop codon context
研究相分离蛋白质中的氨基酸富集与模式：理解液-液相分离中的偏倚	Calvario, J.	PDF	N/A	Investigating Amino acid Enrichments and Patterns in Phase-Separating Proteins: Understanding Biases in Liquid-Liquid Phase Separation
ArfGAP ASAP1中的PH结构域通过一种前所未有的别构机制驱动催化激活。	Soubias, O.	PDF	N/A	The PH domain in the ArfGAP ASAP1 drives catalytic activation through an unprecedented allosteric mechanism
染色质中新DNA甲基化的结构基础	Xie, X.	PDF	N/A	The structural basis for de novo DNA methylation in chromatin
来自哥伦比亚北部上新世的淡水鱼化石与南美洲北部古地理	Ballen, G. A.	PDF	N/A	Fossil Freshwater Fishes from the Pliocene of northern Colombia and the Palaeogeography of northern South America
一种参与类胡萝卜素信号传导的细胞色素P450能够增强植物的光合作用能力和光氧化应激耐受性。	Tiwari, M.	PDF	N/A	A cytochrome P450 involved in apocarotenoid signaling enhances plant photosynthetic capacity and photooxidative stress tolerance
气溶胶沉积影响山毛榉叶的水分吸收和水分流失	Koch, I.	PDF	N/A	Aerosol deposition affects water uptake and water loss of beech leaves
一种脆弱的多巴胺能神经元亚型在帕金森病的早期运动障碍中起驱动作用	Fushiki, A.	PDF	N/A	A Vulnerable Subtype of Dopaminergic Neurons Drives Early Motor Deficits in Parkinson's Disease
在人皮质类器官中，静默突触转化为由AMPA受体介导的功能性突触	Nishimura, M.	PDF	N/A	Conversion of silent synapses to AMPA receptor-mediated functional synapses in human cortical organoids
生成音乐模型揭示了音乐专业知识对音乐的解耦和情境神经编码的影响	Mischler, G.	PDF	N/A	The impact of musical expertise on disentangled and contextual neural encoding of music revealed by generative music models
一种调节性注意门控促进了果蝇的近期记忆表达。	Kapoor, I.	PDF	N/A	A modulatory attentional gate promotes recent memory expression in Drosophila
一种双特异性T细胞结合抗体在实验性同基因和基因工程改造的胶质母细胞瘤模型中展现出强大的活性、特异性和肿瘤微环境重塑能力。	Zannikou, M. Z.	PDF	N/A	A Bi-Specific T Cell-Engaging Antibody Shows Potent Activity, Specificity, and Tumor Microenvironment Remodeling in Experimental Syngeneic and Genetically Engineered Models of GBM
免疫细胞与肾细胞之间的时空相互作用决定了自身免疫性肾病中肾小球新月体的形成。	Sultana, Z.	PDF	N/A	Spatio-temporal interaction of immune and renal cells determines glomerular crescent formation in autoimmune kidney disease
MAETi：在尖端进行轻度酸性洗脱，能够从25,000个细胞中实现定量的免疫肽组学分析。	Beyrle, J.	PDF	N/A	MAETi: Mild acid elution in a tip enables quantitative immunopeptidome profiling from 25,000 cells
益生菌Aliivibrio sp. Vl2株对Moritella viscosa的拮抗机制：基于共培养和转录组分析的证据	Steen Dobloug, M.	PDF	N/A	Antagonistic mechanisms of probiotic Aliivibrio sp. strain Vl2 against Moritella viscosa: Evidence from co-cultivation and transcriptomic analysis
番茄根际微生物群落对植物促生根际细菌合成群落的时序动态响应	Nicotra, D.	PDF	N/A	Temporal Dynamics of the Tomato Rhizosphere Microbiome in Response to Synthetic Communities of Plant Growth-Promoting Rhizobacteria
多组织代谢组学揭示了线粒体DNA和饮食特异性代谢物特征在心肌代谢疾病小鼠模型中的表现	Shastry, A.	PDF	N/A	Multi-Tissue Metabolomics Reveal mtDNA- and Diet-Specific Metabolite Profiles in a Mouse Model of Cardiometabolic Disease
ITGB4通过靶向EZR激活Wnt/β-catenin信号通路，从而促进结直肠癌的进展。	Wang, J.	PDF	N/A	ITGB4 promotes the progression of colorectal cancer by activating Wnt/β-catenin signaling pathway via targeting EZR
MSH2在脆性X综合征中FMR1位点的DNA甲基化维持或重复序列收缩过程中并非必需的。	Grant-Bier, J.	PDF	N/A	MSH2 is not required for either maintenance of DNA methylation or repeat contraction at the FMR1 locus in fragile X syndrome
EnsembleFlex：让蛋白质结构集合分析变得简单	Schneider, M.	PDF	N/A	EnsembleFlex: Protein Structure Ensemble Analysis Made Easy
棕熊在冬眠期间，脂肪组织会激活一种名为胆囊收缩素（CCK）的饱腹感激素通路。	Henriksen, T. I.	PDF	N/A	Brown Bears activates a Satiety Hormone Cholecystokinin (CCK) pathway in adipose tissue during hibernation
染色质调节因子HELLS介导SSB修复及对DNA烷基化损伤的反应。	Joseph, J. T.	PDF	N/A	Chromatin regulator HELLS mediates SSB repair and responses to DNA alkylation damage.
在人类报告iPSC系中，一步全RNA引导编辑系统实现了接近100%的基因编辑效率。	Wettschurack, K.	PDF	N/A	Near 100% genome editing efficiency with a one-step all RNA prime editing system in a human reporter iPSC line
果蝇和赤拟谷盗之间中线轴突导向活性的进化保守性	Ghosh, P.	PDF	N/A	Evolutionary conservation of midline axon guidance activity between Drosophila and Tribolium Frazzled
对Sarpagan和Akuammiline生物碱生物合成过程的立体化学洞察	Mann, S. G. A.	PDF	N/A	Stereochemical Insights into Sarpagan and Akuammiline Alkaloid Biosynthesis
肼苯哒嗪通过抑制胱胺双加氧酶来治疗先兆子痫并促使胶质母细胞瘤衰老。	Shishikura, K.	PDF	N/A	Hydralazine inhibits cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma
CYP152过氧化物酶对非羧酸底物的意外活性揭示了新的底物识别机制和催化多功能性。	Jiang, Y.	PDF	N/A	Unexpected Activities of CYP152 Peroxygenases towards Non-carboxylic Substrates Reveal Novel Substrate Recognition Mechanism and Catalytic Versatility
FANCJ DNA解旋酶继续组装G-四链体修复复合物	Campbell, L.	PDF	N/A	A continuation of the assembly of a G-quadruplex repair complex by the FANCJ DNA helicase
将组蛋白H2B变体整合到染色质中会改变染色质的可及性，从而诱导乳腺癌中的上皮-间质转化。	Dhahri, H.	PDF	N/A	Incorporating histone H2B variants into chromatin modifies chromatin accessibility to induce epithelial to mesenchymal transition in breast cancer
生物工程酵母锚定的呼吸超级复合物揭示了高效底物利用的调控机制	Eldeeb, M. H.	PDF	N/A	Bioengineered yeast tethered respiratory supercomplexes reveal mechanisms governing efficient substrate utilization
抗分枝杆菌套索肽Triculamin的趋同进化	Merrild, A.	PDF	N/A	Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin
突破交联质谱法的界限：借助Orbitrap Astral质谱分析仪提升通量与灵敏度	Mueller, F.	PDF	N/A	Breaking Barriers in Crosslinking Mass Spectrometry: Enhanced Throughput and Sensitivity with the Orbitrap Astral Mass Analyzer
双交联？关于甲基球菌细胞色素P460中一种异常交联的血红素的结构和计算研究	Pfalzgraf, H. E.	PDF	N/A	Double crossed? Structural and computational studies of an unusual crosslinked heme in Methylococcus capsulatus cytochrome P460
脂质在冷冻电镜条件下调节RyR1的开放概率	Li, C.	PDF	N/A	Lipids modulate open probability of RyR1 under cryo-EM conditions
噬菌体展示合成文库和纳米抗体筛选平台	Xia, B.	PDF	N/A	Phage-displayed synthetic library and screening platform for nanobody discovery
SpaceExpress：一种基于组织内在坐标系统的比较空间转录组学方法	Kim, Y.	PDF	N/A	SpaceExpress: a method for comparative spatial transcriptomics based on intrinsic coordinate systems of tissues
稳定插入缺失突变的结构和能量分析	Gutierrez, Y. M.	PDF	N/A	Structural and energetic analysis of stabilizing indel mutations
# BioRxiv 2024-12-20 Papers

标题	作者	PDF链接	代码仓库	Title
一个从生理特征预测人类生物学年龄的数学模型，揭示了影响衰老的环境和遗传因素。	Libert, S.	PDF	N/A	A mathematical model that predicts human biological age from physiological traits identifies environmental and genetic factors that influence aging
小鼠体内电生理测量的可重复性	The International Brain Laboratory,	PDF	N/A	Reproducibility of in-vivo electrophysiological measurements in mice
表面信号网络的拓扑学研究及其对神经动力学的可能影响	Sen, S.	PDF	N/A	A Topological Study of a Surface Signaling Network and Possible Implications for Neural Dynamics
全面分析通过鼻腔给药诱导的SARS-CoV-2刺突蛋白鼻IgA抗体	Waki, K.	PDF	N/A	Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein
一张复杂行为期间大脑神经活动全图	International Brain Lab,	PDF	N/A	A Brain-Wide Map of Neural Activity during Complex Behaviour
一张复杂行为过程中大脑神经活动的全面图谱	International Brain Lab,	PDF	N/A	A Brain-Wide Map of Neural Activity during Complex Behaviour
根据色彩空间的对称性预测色彩匹配实验中的反应	Vattuone, N.	PDF	N/A	Predicting the responses in colour matching experiments from the symmetries of colour space
阿克曼菌（Akkermansia muciniphila）被鉴定为通过Wnt信号通路缓解肠道屏障损伤的关键菌株。	Ma, X.	PDF	N/A	Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway
从Seven Springs，Martlesham，萨福克的新石器时代早期森林耕作，通过沉积物DNA和花粉推断。	Hudson, S. M.	PDF	N/A	Early Neolithic forest farming at Seven Springs, Martlesham, Suffolk inferred from sedaDNA and pollen
综合分析揭示吡维氯铵在默克尔细胞癌中的治疗潜力	Yang, J.	PDF	N/A	Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma
普罗克鲁斯提恩图：一种用于快速k-mer大小分析的子串索引	Park, A.	PDF	N/A	Prokrustean Graph: A substring index for rapid k-mer size analysis
基于聚光灯的逐试次fMRI解码在存在试次间相关性的情况下	Soch, J.	PDF	N/A	Searchlight-based trial-wise fMRI decoding in the presence of trial-by-trial correlations
ERK、JNK和p38 MAP激酶对连接蛋白43的差异性底物特异性	Latchford, L. P.	PDF	N/A	Differential substrate specificity of ERK, JNK, and p38 MAP kinases toward Connexin 43
幼年斑马鱼通过多感官控制姿势和运动来维持高度	Davis, S. N.	PDF	N/A	Larval zebrafish maintain elevation with multisensory control of posture and locomotion
iPAR：一种用于真核细胞质蛋白聚集的新型报告分子	Lecinski, S.	PDF	N/A	iPAR: a new reporter for eukaryotic cytoplasmic protein aggregation
一个关于Ca2+/钙调蛋白依赖性蛋白激酶II（CaMKII）自磷酸化的空间模型预测，通过钙调蛋白捕获，突触可塑性诱导后磷酸化CaMKII的寿命会大大延长。	Bartol, T. M.	PDF	N/A	A spatial model of autophosphorylation of Ca2+/calmodulin-dependent proteinkinase II (CaMKII) predicts that the lifetime of phospho-CaMKII after induction ofsynaptic plasticity is greatly prolonged by CaM-trapping.
全长BEND2蛋白对小鼠的精子发生并非必需，但在调节卵巢储备方面是必需的。	Huang, Y.	PDF	N/A	The full length BEND2 protein is dispensable for spermatogenesis but required for setting the ovarian reserve in mice
社会接触塑造了裸鼹鼠的交流和动物识别能力。	Schwark, R.	PDF	N/A	Social touch shapes communication and animal recognition in naked mole-rats
莫努匹拉韦和奈玛特韦对COVID-19重症模型中SARS-CoV-2基因组多样性的影响。	Penrice-Randal, R.	PDF	N/A	The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19.
鉴定可药物结合位点和小分子作为TMC1的调节剂	De-la-Torre, P.	PDF	N/A	Identification of Druggable Binding Sites and Small Molecules as Modulators of TMC1
探索感染性非编码环状RNA中的RNA修饰	Vopalensky, P.	PDF	N/A	Exploring RNA modifications in infectious non-coding circular RNAs
白蚁基因组中出乎意料的低重组率和热点存在	Everitt, T.	PDF	N/A	Unexpectedly low recombination rates and presence of hotspots in termite genomes
脊髓运动神经元的兴奋性通过β-肾上腺素能神经调节在野生型和症状前SOD1小鼠中进行稳态调控。	Antonucci, S.	PDF	N/A	Spinal motoneuron excitability is homeostatically-regulated through β-adrenergic neuromodulation in wild-type and presymptomatic SOD1 mice
评估化学方法去除艰难梭菌孢子外壳和外孢子层的效果	Sanchez-Peralta, J.	PDF	N/A	Assessment of chemical methods in the removal of the spore coat and exosporium layers of Clostridioides difficile Spores
受体细胞通过旁分泌粘附信号促进对小细胞外囊泡的摄取。	Hirosawa, K. M.	PDF	N/A	The uptake of small extracellular vesicles by recipient cells is facilitated by paracrine adhesion signaling
PAbFold：使用AlphaFold2进行线性抗体表位预测	DeRoo, J.	PDF	N/A	PAbFold: Linear Antibody Epitope Prediction using AlphaFold2
MSLASpheroidStamp：为每个人提供3D细胞球体	Minin, A. S.	PDF	N/A	MSLASpheroidStamp: 3d cell spheroids for everyone
在估计群体平均多基因评分历史的背景下评估ARG估计方法	Peng, D.	PDF	N/A	Evaluating ARG-estimation methods in the context of estimating population-mean polygenic score histories
在循环神经网络模型中，Hebbian可塑性导致了多种感知偏差的产生。	Schönsberg, F.	PDF	N/A	Diverse perceptual biases emerge from Hebbian plasticity in a recurrent neural network model
发现并机制表征了一种源自益生菌的3β-OH-Δ5-6-胆固醇-5β-还原酶，可直接将胆固醇转化为粪甾醇	Netter, U.	PDF	N/A	Discovery and mechanistic characterization of a probiotic-origin 3β-OH-Δ5-6-cholesterol-5β-reductase directly converting cholesterol to coprostanol
UNC-6/Netrin 在单个轴突内同时促进粘附和定向生长	Nichols, E. L.	PDF	N/A	UNC-6/Netrin promotes both adhesion and directed growth within a single axon
听觉皮层中音高感知的动力学	Abrams, E. B.	PDF	N/A	Dynamics of pitch perception in the auditory cortex
用于人类大脑及其他生物模型的关联光学与电子显微镜技术	Shafiei, N.	PDF	N/A	Correlative light and electron microscopy for human brain and other biological models
通过深度神经网络中的分类嵌入优化药物协同预测	Gonzalez Lastre, M.	PDF	N/A	Optimizing drug synergy prediction through categorical embeddings in Deep Neural Networks
AI辅助解析分子特征，这些特征对于非向光性下胚轴3的凝聚及其在向光性中的功能至关重要。	Manishankar, P.	PDF	N/A	AI-assisted decoding of molecular signatures essential for NON-PHOTOTROPIC HYPOCOTYL3 condensation and function in phototropism
通过招募关键免疫细胞在可注射水凝胶储库中生成炎症微环境，可提高mRNA疫苗的效力。	Meany, E. L.	PDF	N/A	Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines
人类有目标的行动准备涉及皮质脊髓神经计算的混合过程。	Wadsley, C. G.	PDF	N/A	Goal-directed action preparation in humans entails a mixture of corticospinal neural computations
肌肉和肠道的innexins与肌肉的Deg/Enac通道共同促进肌肉协调和胚胎延长。	LLENSE, F.	PDF	N/A	Muscle and intestine innexins with muscle Deg/Enac channels promote muscle coordination and embryo elongation
性依赖性胃肠道定植抗性对MRSA的抵抗是依赖于微生物群和Th17的	Lejeune, A.	PDF	N/A	Sex-dependent gastrointestinal colonization resistance to MRSA is microbiota and Th17 dependent
组织坏死后的再生过程是通过非凋亡性caspase活性介导的。	Klemm, J.	PDF	N/A	Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity
神经肽Sulfakinin是一种外周调节因子，能够调控昆虫在交配和觅食行为之间的转换。	Li, H.-F.	PDF	N/A	The Neuropeptide Sulfakinin, a peripheral regulator of insect behavior switch between mating and foraging
基于质心功分析估计首选步行速度	Hosseini-Yazdi, S.-S.	PDF	N/A	Estimating the Preferred Walking Speeds Based on the Center of Mass Work Analysis
新开发的基于结构的分析方法在大规模系统发育分析中并未优于标准的基于序列的分析方法。	Mutti, G.	PDF	N/A	Newly developed structure-based methods do not outperform standard sequence-based methods for large-scale phylogenomics
突触细胞粘附分子Cdh6识别出一类具有结肠运动新功能的感觉神经元	Gomez-Frittelli, J.	PDF	N/A	Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility
在存在基因重复的情况下，进行系统基因组学预测的相互作用网络	Forsythe, E. S.	PDF	N/A	Phylogenomic prediction of interaction networks in the presence of gene duplication
物候特征的协同进化塑造了植物-传粉者共存	Duchenne, F.	PDF	N/A	Coevolution of phenological traits shapes plant-pollinator coexistence
黑腹果蝇（Drosophila melanogaster）的色素沉着在多个时间尺度上展示了适应性表型平行现象。	Berardi, S.	PDF	N/A	Drosophila melanogaster pigmentation demonstrates adaptive phenotypic parallelism over multiple timescales
图像引导的线粒体代谢靶向增强了儿童恶性横纹肌样瘤对低剂量放疗的敏感性	Xia, W.	PDF	N/A	Image-Guided Targeting of Mitochondrial Metabolism Sensitizes Pediatric Malignant Rhabdoid Tumors to Low Dose Radiotherapy
序列动作表征在快速技能学习过程中进行情境化处理。	Dash, D.	PDF	N/A	Sequence action representations contextualize during rapid skill learning
评估森林管理与气候变化对欧洲山毛榉森林碳和水通量的综合影响	Saponaro, V.	PDF	N/A	Assessing the combined effects of forest management and climate change on carbon and water fluxes in European beech forests
编排不可能的化学反应：依赖B12的甲硫氨酸合成酶催化过程的结构快照	Mendoza, J.	PDF	N/A	Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography
空间结构通过药物抗性促进进化救援	Fruet, C.	PDF	N/A	Spatial structure facilitates evolutionary rescue by drug resistance
一种FUCCI传感器揭示了弓形虫内二芽殖的复杂细胞周期组织	Batra, M.	PDF	N/A	A FUCCI sensor reveals complex cell cycle organization of Toxoplasma endodyogeny
计算癌症治疗的斯塔克尔伯格均衡	Ganzfried, S.	PDF	N/A	Computing Stackelberg Equilibrium for Cancer Treatment
在细胞分化过程中，Caspase激活的脱氧核糖核酸酶（DNase）定位于导致癌症的易位断裂点	Alsowaida, D.	PDF	N/A	Caspase-Activated DNase Localizes to Cancer Causing Translocation Breakpoints During Cell Differentiation
联合PARP14抑制与PD-1阻断促进复发性黑色素瘤中细胞毒性T细胞的静息状态并调节巨噬细胞极化	Leshem, R.	PDF	N/A	Combined PARP14 Inhibition and PD-1 Blockade Promotes Cytotoxic T Cell Quiescence and Modulates Macrophage Polarisation in Relapsed Melanoma
生物学启发的皮层模型预测光遗传学扰动	Sourmpis, C.	PDF	N/A	Biologically informed cortical models predict optogenetic perturbations
从头设计能够结合萘二酰亚胺的蛋白质，萘二酰亚胺是一种具有可调光物理性质的强大光氧化剂。	Mann, S. I.	PDF	N/A	De novo design of proteins that bind naphthalenediimides, powerful photooxidants with tunable photophysical properties
映射布尔网络的吸引子景观	Trinh, V.-G.	PDF	N/A	Mapping the attractor landscape of Boolean networks
神经运动生成的背后空间和网络原理	Komi, S.	PDF	N/A	Spatial and network principles behind neural generation of locomotion
通过编码流形揭示的小鼠视觉皮层区域的功能组织与自然场景响应	Dyballa, L.	PDF	N/A	Functional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds
气候变化、天气和地理因素共同塑造了整个北美西部种子质量的变化和下降趋势。	Lenzo, L.	PDF	N/A	Climate change, weather, and geography shape seed mass variation and decline across western North America
来自产气荚膜梭菌的IV型菌毛相关分泌的一种生物膜基质蛋白，该蛋白通过形成分子间异肽键来发挥作用。	Kivimaki, S. E.	PDF	N/A	Type IV pili-associated secretion of a biofilm matrix protein from Clostridium perfringens that forms intermolecular isopeptide bonds
基于逻辑的机器学习预测艾司西酞普兰如何减轻心肌细胞肥大	Eggertsen, T. G.	PDF	N/A	Logic-based machine learning predicts how escitalopram attenuates cardiomyocyte hypertrophy
两亲性螺旋通过脂质堆积缺陷感知内核膜环境	Lee, S.	PDF	N/A	Amphipathic helices sense the inner nuclear membrane environment through lipid packing defects
回到角的问题：通过不同类型的重组事件重建祖先角的原始状态。	Upadhyay, M.	PDF	N/A	Back to the horns: a reconstruction of the ancestral horn state through distinct types of recombination events.
一个从3446张全切片图像中通过自监督学习发现的切除间皮瘤的组织形态学图谱	Seyedshahi, F.	PDF	N/A	A histomorphological atlas of resected mesothelioma discovered by self-supervised learning from 3446 whole-slide images
植物易感性的组织依赖性：通过根部和叶片对系统性植物病原菌Ralstonia pseudosolanacearum在茄子和番茄幼苗中的致病性比较研究	Bhuyan, S.	PDF	N/A	Tissue-dependent nature of plant susceptibility: a comparative pathogenicity study of the systemic phytopathogen Ralstonia pseudosolanacearum in eggplant and tomato seedlings through root and leaf
经过工程改造的CRISPR-Base编辑器：家族性自主神经异常的永久性治疗方法	Yun, S.	PDF	N/A	Engineered CRISPR-Base Editors as a Permanent Treatment for Familial Dysautonomia
宫颈阴道微生物特征可预测感染女性沙眼衣原体向上生殖道的传播	Jeong, S.	PDF	N/A	Cervicovaginal microbial features predict Chlamydia trachomatis spread to the upper genital tract of infected women
秀丽隐杆线虫的huntingtin蛋白，即htt-1，在应激条件下能够促进强效的自噬诱导并提高生存率。	Chung, C. H.	PDF	N/A	C. elegans huntingtin, htt-1, promotes robust autophagy induction and survival under stress conditions
芯片上流体诱导的血管重塑：对抗VEGF疗法的启示	Mirzapour-Shafiyi, F.	PDF	N/A	Flow-Induced Vascular Remodeling On-Chip: Implications for Anti-VEGF Therapy
扩展HP1a结合的共识序列和异染色质组装的分子语法	Colmenares, S. U.	PDF	N/A	Expanding the HP1a-binding consensus and molecular grammar for heterochromatin assembly
使用AlphaFold2预测肽的结构构象	Ille, A. M.	PDF	N/A	Prediction of peptide structural conformations with AlphaFold2
自发脑活动背后的神经受体和转运蛋白	Nakuci, J.	PDF	N/A	The neuroreceptors and transporters underlying spontaneous brain activity
捕食者与猎物互动中的诚实信号：检验资源分配假说	Burdfield-Steel, E.	PDF	N/A	Honest signalling in predator-prey interactions: testing the resource allocation hypothesis
果蝇（Drosophila melanogaster）头部基因表达随年龄变化的动态变化	Hanson, K. M.	PDF	N/A	Dynamic Changes in Gene Expression Through Aging in Drosophila melanogaster Heads
形态发生约束在类原肠胚发育中的作用：对小鼠原肠形成的影响	Fiuza, U.-M.	PDF	N/A	Morphogenetic constrains in the development of gastruloids: implications for mouse gastrulation
NRBP1假激酶在渗透压应激下结合并激活WNK通路。	Amnekar, R.	PDF	N/A	NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress
锥体细胞和中间神经元在尖波波纹的作用下被强烈地重新激活。	Javed, M. H.	PDF	N/A	cfos principal cells and interneurons are strongly reactivated by sharp wave ripples
斑马鱼罗盘神经元中塑料地标锚定的机制	Tanaka, R.	PDF	N/A	Mechanisms for plastic landmark anchoring in zebrafish compass neurons
UTX通过表观遗传方式在自身反应性干细胞样CD8+ T细胞前体中强制执行一种细胞溶解效应程序。	Chen, H.-C.	PDF	N/A	UTX Epigenetically Imposes a Cytolytic Effector Program in Autoreactive Stem-like CD8+ T cell Progenitors
对不同海葵物种的毒素基因家族进行了比较分析	Smith, H. L.	PDF	N/A	A comparative analysis of toxin gene families across diverse sea anemone species
EpiPAMPAS：通过简约祖先状态重建和计数突变快速检测蛋白质内上位性	Dabbaghie, F.	PDF	N/A	EpiPAMPAS: Rapid detection of intra-protein epistasis via parsimonious ancestral state reconstruction and counting mutations
将机械敏感离子通道Piezo进行靶向和锚定，以促进其对轴突再生的抑制作用	Song, Y.	PDF	N/A	Targeting and anchoring the mechanosensitive ion channel Piezo to facilitate its inhibition of axon regeneration
随机连接性产生了抑制性微电路，这些微电路在视觉皮层中解除了适应的相关性。	Kosiachkin, Y.	PDF	N/A	Random connectivity generates inhibitory microcircuits that decorrelate adaptation in visual cortex
错失眼前之物：人类在食欲性和厌恶性听觉-嗅觉条件反射中的失败	Menger, N. S.	PDF	N/A	Missing what is right under your nose: failed appetitive and aversive audio-olfactory conditioning in humans
在寿命和衰老研究中，Kolmogorov-Smirnov和Shapiro-Wilk单分布分析方法用于检验样本结构、遗传背景的强度以及干预措施的效果。	Konopatov, A. V.	PDF	N/A	Kolmogorov-Smirnov and Shapiro-Wilk single distribution analysis methods in examining sample structure, strength of genetic background, and effects of interventions in lifespan and aging studies
通过Orbitrap星型质谱和串联质量标签（TMT）整合扩展衰老研究领域	Keele, G. R.	PDF	N/A	Expanding the Landscape of Aging via Orbitrap Astral Mass Spectrometry and Tandem Mass Tag (TMT) Integration
通过获得性功能突变进行的代谢重编程克服了金黄色葡萄球菌中plsX基因的必需性。	Gruss, A.	PDF	N/A	Metabolic rerouting by gain-of-function mutations overcomes plsX essentiality in Staphylococcus aureus
链球菌M3蛋白识别胶原蛋白的结构基础及其在生物膜形成中的作用	Wojnowska, M.	PDF	N/A	Structural basis for collagen recognition by the Streptococcus pyogenes M3 protein and its involvement in biofilm
解锁一种栽培巨型噬菌体的基因组序列	Buchan, A.	PDF	N/A	Unlocking the genomic repertoire of a cultivated megaphage
病毒RNA的假结结构揭示了一种保守的机制，用于抵抗程序性外切核酸酶的降解。	Gezelle, J. G.	PDF	N/A	The pseudoknot structure of a viral RNA reveals a conserved mechanism for programmed exoribonuclease resistance
通用接受系统作为一种新型调节器，在白细胞生成抗菌和抗癌生物活性化合物的过程中发挥作用。	Tetz, V.	PDF	N/A	The Universal Receptive System acts as a novel regulator in the production of antimicrobial and anticancer bioactive compounds by white blood cells
犬类衰老项目中伴侣犬的首个共病网络	Fang, A.	PDF	N/A	The first comorbidity networks in companion dogs in the Dog Aging Project
多物种关系塑造了鸟类喂养行为。	Aivelo, T.	PDF	N/A	Multispecies relations shape bird-feeding practices
传染病动力学研究中性别和种族/民族失衡的程度及驱动因素	Taube, J. C.	PDF	N/A	The extent and drivers of gender and race/ethnicity imbalance in infectious disease dynamics research
使用德尔菲法为非专业入门生物学制定学习目标的发展	Brickman, P.	PDF	N/A	Development of Learning Objectives for Non-Major Introductory Biology Using a Delphi Method
StreptoCAD：一种开源软件工具箱，用于自动化链霉菌中的基因组工程工作流程	Levassor, L.	PDF	N/A	StreptoCAD: An open-source software toolbox automating genome engineering workflows in streptomycetes
急性至慢性疼痛特征（A2CPS）项目中的图像处理	Sadil, P.	PDF	N/A	Image Processing in the Acute to Chronic Pain Signatures (A2CPS) Project
新西兰患有特发性生长不良综合征的牧场牛只的口腔和粪便病毒组	Grimwood, R. M.	PDF	N/A	Oral and faecal viromes of New Zealand calves on pasture with an idiopathic ill-thrift syndrome
早期抗生素和益生菌治疗对极低出生体重早产儿肠道微生物群和抗性组的影响	Kiu, R.	PDF	N/A	Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants
Viro3D：一个全面的病毒蛋白结构预测数据库	Litvin, U.	PDF	N/A	Viro3D: a comprehensive database of virus protein structure predictions
血管内皮生长因子D在急性肺损伤期间改善肺血管完整性	Yuan, Y.	PDF	N/A	Vascular endothelial growth factor-D improves lung vascular integrity during acute lung injury
在甲藻物种中细胞穿透肽的转运	Gorrie, D. M.	PDF	N/A	Cell-Penetrating Peptide Translocation in Haptophyte Species
染色体周围区域是卵母细胞染色体的重要组成部分。	Simpson, E. L.	PDF	N/A	The Chromosome Periphery is an Essential Compartment of Oocyte Chromosomes
空间扰动测序（Spatial Perturb-Seq）：在完整组织结构中进行单细胞功能基因组学研究	Shen, K.	PDF	N/A	Spatial Perturb-Seq: Single-Cell Functional Genomics within Intact Tissue Architecture
Remodelin对小鼠肌细胞分化的抑制作用	Sian, V.	PDF	N/A	The inhibitory effects of Remodelin on murine myoblasts differentiation
DNAJC13定位于内体的过程受到其J结构域及其无序C端尾部的对抗。	Adoff, H.	PDF	N/A	DNAJC13 localization to endosomes is opposed by its J domain and its disordered C-terminal tail
在曲霉菌感染期间，肺成纤维细胞的激活通过免疫调节和组织重塑增强了肺部防御。	Guirao-Abad, J. P.	PDF	N/A	Pulmonary fibroblast activation during Aspergillus fumigatus infection enhances lung defense via immunomodulation and tissue remodeling
秀丽隐杆线虫核仁中的RG重复序列足以实现核仁积累，但不足以实现核仁亚区室的划分。	Spaulding, E. L.	PDF	N/A	C. elegans nucleolar RG repeats are sufficient for nucleolar accumulation but insufficient for sub-nucleolar compartmentalization
蝾螈大脑中的神经元激活促进了脊髓再生	Walker, S.	PDF	N/A	Neuronal activation in the axolotl brain promotes spinal cord regeneration
Wnt通路的调控对于在颅神经管闭合过程中正确执行多个独立的细胞动态程序是必需的。	Bogart, A. H.	PDF	N/A	Wnt pathway modulation is required to correctly execute multiple independent cellular dynamic programs during cranial neural tube closure
微生物组介导性状的定量遗传学	Week, B.	PDF	N/A	Quantitative Genetics of Microbiome Mediated Traits
调控金鱼望远眼和天眼发育的LRP2基因的平行进化	Li, R.	PDF	N/A	Parallel evolution of LRP2 gene mediating telescope-eye and celestial-eye in goldfish
低温电子断层扫描与线粒体颗粒的元素分析在人类视网膜神经节细胞中的应用	Wu, G.-H.	PDF	N/A	Cryogenic electron tomography and elemental analysis of mitochondrial granules in human retinal ganglion cells
解决人类AMPylase FicD的TPR结构域中构象状态的动态相互作用	Runge, S.	PDF	N/A	Resolving the Dynamic Interplay of the Conformational States in the TPR Domain of Human AMPylase FicD
CSF1R-CAR T细胞诱导CSF1R信号传导并促进癌细胞生长。	Callahan, A.	PDF	N/A	CSF1R-CAR T cells induce CSF1R signalling and promote cancer cell growth
非经典葡萄糖代谢重编程使癌细胞对靶向疗法产生抗性	Zhu, L.	PDF	N/A	A non-canonical glucose metabolic rewiring enables resistance to cancer targeted therapy
肌动蛋白失调通过氧化应激激活的PD-L1在胃癌中引发免疫逃逸	Seo, Y.	PDF	N/A	Actin dysregulation induces immune evasion via oxidative stress-activated PD-L1 in gastric cancer
更简单的预测模型在卵巢癌检测中提供了更高的准确性。	Wood, D. E.	PDF	N/A	Simpler predictive models provide higher accuracy for ovarian cancer detection
衰老突触：蛋白质组学与转录组学综合分析	Caterino, C.	PDF	N/A	The Aging Synapse: An Integrated Proteomic And Transcriptomic Analysis
Syngap1与小鼠新皮质祖细胞的发育	Barao, S.	PDF	N/A	Syngap1 and the development of murine neocortical progenitor cells
研究鞘磷脂酶对胞外囊泡货物分选的影响	Padilla, J.-C. A.	PDF	N/A	Investigating the Impacts of Sphingomyelinases on Extracellular Vesicle Cargo Sorting
磷脂酰肌醇-3,5-二磷酸介导的液泡形态调节是乙醇胁迫反应的重要组成部分。	Mandal, P.	PDF	N/A	Phosphatidylinositol-3,5-bisphosphate mediated vacuolar morphology modulation is integral to ethanol stress response
拟南芥14-3-3蛋白通过稳定质膜上的油菜素内酯不敏感1（BRASSINOSTEROID INSENSITIVE1）来正向调控油菜素内酯信号传导。	Liu, D.	PDF	N/A	The Arabidopsis 14-3-3 proteins positively regulate brassinosteroid signaling by stabilizing BRASSINOSTEROID INSENSITIVE1 at the plasma membrane
细胞周期中的核代谢振荡揭示了磷脂酰肌醇途径与组蛋白甲基化之间的联系。	Ganez-Zapater, A.	PDF	N/A	Nuclear metabolism oscillation during the cell cycle reveals a link between the phosphatidylinositol pathway and histone methylation.
NUAK1调控源自腹主动脉瘤患者的血管平滑肌细胞的收缩。	Rombouts, K. B.	PDF	N/A	NUAK1 regulates contraction in vascular smooth muscle cells derived from abdominal aortic aneurysm patients
利用360度视频和空间音频解读珊瑚礁声音景观	Dantzker, M. S.	PDF	N/A	Deciphering Coral Reef Soundscapes Utilizing 360 Video and Spatial Audio
抑制果蝇（Drosophila melanogaster）着丝粒异染色质中的减数分裂交叉需要联会复合体和减数分裂重组因子	Pazhayam, N. M.	PDF	N/A	Suppression of meiotic crossovers in pericentromeric heterochromatin requires synaptonemal complex and meiotic recombination factors in Drosophila melanogaster
用于检测三联重复序列扩展的TRX检测方法	O'Brien, T.	PDF	N/A	The TRX assay for triplet repeat expansions
电场诱导的人类Kv2.1通道孔收缩	Mandala, V. S.	PDF	N/A	Electric field-induced pore constriction in the human Kv2.1 channel
DTPSP：一种用于时间序列单细胞研究中优化时间点选择的深度学习框架	Hijazin, M.	PDF	N/A	DTPSP: A Deep Learning Framework for Optimized Time Point Selection in Time-Series Single-Cell Studies
一种全3D打印的低成本组织学成像光学显微镜	Christopher, J.	PDF	N/A	A fully 3D-printed optical microscope for low-cost histological imaging
富含芳香族残基的带电肽减缓了由交叉β-折叠形成驱动的凝聚物老化过程。	Sanchez-Burgos, I.	PDF	N/A	Charged peptides enriched in aromatic residues decelerate condensate ageing driven by cross-beta-sheet formation
GlioME：一种保留胶质瘤微环境的新型类器官模型，用于个性化药物筛选和治疗评估	Zheng, C.	PDF	N/A	GlioME: A Novel Organoid Model Retaining the Glioma Mi-croenvironment for Personalized Drug Screening and Thera-peutic Evaluation
靶向从头脂质生成可提高胰腺导管腺癌中吉西他滨的疗效	Hancock, S. E.	PDF	N/A	Targeting de novo lipogenesis improves gemcitabine efficacy in pancreatic ductal adenocarcinoma
一个结合了低氧、机械感应和TGF-β信号传导的布尔网络模型，揭示了表型可塑性和突变在肿瘤转移中的作用。	Greene, G.	PDF	N/A	A Boolean network model of hypoxia, mechanosensing and TGF-β signaling captures the role of phenotypic plasticity and mutations in tumor metastasis
代谢组学分析揭示了烟酰胺在宫颈癌进展中的分级特异性积累及其通过SIRT1-CD38-EMT轴调节的治疗潜力	Jaiswal, S.	PDF	N/A	Metabolomic profiling reveals grade-specific niacinamide accumulation and its therapeutic Potential via SIRT1-CD38-EMT axis modulation in cervical cancer progression
WNT7B驱动胰腺癌亚型转换和进展的程序	Sprangers, J.	PDF	N/A	WNT7B drives a program for pancreatic cancer subtype switching and progression
转移灶对其宿主组织的基因表达适应	Nagel, L.	PDF	N/A	Gene expression adaptation of metastases to their host tissue
BRAF V600和ErbB抑制剂通过非靶向方式直接激活GCN2，从而限制癌细胞的增殖。	Ill, C. R.	PDF	N/A	BRAF V600 and ErbB inhibitors directly activate GCN2 in an off-target manner to limit cancer cell proliferation
激酶可塑性对凡德他尼的响应增强了对他莫昔芬的敏感性，并揭示了雌激素受体阳性乳腺癌中的联合治疗策略	Kakati, R. T.	PDF	N/A	Kinase Plasticity in Response to Vandetanib Enhances Sensitivity to Tamoxifen and Identifies Co-Treatment Strategies in Estrogen Receptor Positive Breast Cancer
预测由皮质动力学和面部表情引发的压力诱导快感缺乏的未来发展	Coley, A.	PDF	N/A	Predicting Future Development of Stress-Induced Anhedonia From Cortical Dynamics and Facial Expression
宿主和狂犬病病毒基因表达受到人脑细胞类型的影响，并揭示了星形胶质细胞中预先存在的促进病毒转录的状态。	Feige, L.	PDF	N/A	Host and rabies virus gene expression is shaped by human brain cell type and reveals a preexisting pro-viral transcriptional state in astrocytes
C1q和免疫球蛋白介导成年大脑中依赖活动的突触丢失。	Crowley, G.	PDF	N/A	C1q and immunoglobulins mediate activity-dependent synapse loss in the adult brain
抑制金属蛋白酶ADAM19作为一种新型延缓衰老策略，通过调节衰老相关分泌表型（SASP）来改善肠道通透性和衰老标志物。	Bar, S.	PDF	N/A	Inhibition of the metalloprotease ADAM19 as a Novel Senomorphic Strategy to Ameliorate gut permeability and senescence markers by modulating senescence-associated secretory phenotype (SASP)
通过综合单细胞组学分析预测人类角膜的细胞状态及关键转录因子	Arts, J. A.	PDF	N/A	Prediction of Cell States and Key Transcription Factors of the Human Cornea through Integrated Single-Cell Omics Analyses
野火烟雾和柴油尾气对老化人脑微胶质细胞炎症反应的影响	Cuni-Lopez, C.	PDF	N/A	Impact of wildfire smoke and diesel exhaust on inflammatory response in aging human microglia
Tonic ERK信号传导调节青春期前大鼠Sertoli细胞的基础乳酸生成。	GAUTAM, M.	PDF	N/A	Tonic ERK signaling regulate the basal lactate production in prepubertal rat Sertoli cell
异质性局部钙离子动态的独特时空同步解决方案是心脏窦房结产生每个脉冲的基础。	Tagirova, S.	PDF	N/A	Unique spatiotemporal synchronization solutions of heterogeneous local Ca2+ dynamics underlie the formation of each impulse that emerges from the cardiac sinoatrial node
tRNA片段的转录后修饰在动脉粥样硬化中赋予高密度脂蛋白功能性变化	Semler, E. M.	PDF	N/A	Post-transcriptional modifications on tRNA fragments confer functional changes to high-density lipoproteins in atherosclerosis
Wnt/β-Catenin通过调控囊泡分化、梭内纤维核聚集及本体感受神经末梢的形成，协调肌梭的发育。	Guo, Q.	PDF	N/A	Wnt/β-Catenin coordinates muscle spindle development by regulating capsule differentiation, intrafusal fiber nuclei aggregation and proprioceptive nerve endings
通过与LINE-1调控元件结合，组蛋白甲基转移酶EHMT2协同抑制全能性相关基因位点的表达。	Chatterjee, K.	PDF	N/A	Coordinated repression of totipotency-associated gene loci by histone methyltransferase EHMT2 through binding to LINE-1 regulatory elements
Janus A基因编码一种polo激酶，该激酶的缺失会导致纤毛虫四膜虫（Tetrahymena）中背腹轴的细胞内同源异形现象。	Cole, E. S.	PDF	N/A	The Janus A gene encodes a polo-kinase whose loss creates a dorsal/ventral intracellular homeosis in the ciliate, Tetrahymena.
使用TARDIS可以准确且快速地分割显微照片和断层扫描图像中的纤维和膜结构。	Kiewisz, R.	PDF	N/A	Accurate and fast segmentation of filaments and membranes in micrographs and tomograms with TARDIS
稀疏多任务组套索算法在全基因组关联研究中的应用	Nouira, A.	PDF	N/A	Sparse Multitask group Lasso for Genome-Wide Association Studies
MorphoDiff：基于扩散模型的细胞形态绘制	Navidi, Z.	PDF	N/A	MorphoDiff: Cellular Morphology Painting with Diffusion Models
阳离子/质子反向转运蛋白中组氨酸分子开关的构象动力学	Pecorilla, C.	PDF	N/A	Conformational dynamics of a histidine molecular switch in a cation/proton antiporter
血液中的免疫细胞携带了结直肠癌或炎症性肠病患者体内微生物的低生物量DNA残留。	Morsy, Y.	PDF	N/A	Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease
PI3Ka的RAS结合域的共价抑制剂可抑制由RAS和HER2驱动的肿瘤生长。	Klebba, J. E.	PDF	N/A	Covalent inhibitors of the RAS binding domain of PI3Ka impair tumor growth driven by RAS and HER2
CD38双等位基因缺失是多发性骨髓瘤中抗CD38抗体耐药的常见机制。	Diamond, B.	PDF	N/A	CD38 biallelic loss is a recurrent mechanism of resistance to anti-CD38 antibodies in multiple myeloma.
Trastuzumab deruxtecan联合治疗显著增强疗效，并克服KRASG12C突变型非小细胞肺癌对sotorasib的耐药性。	Ozakinci, H.	PDF	N/A	Trastuzumab deruxtecan combination strongly enhances responses and overcomes sotorasib resistance in KRASG12C-mutant NSCLC
在放射治疗后针对Bcl-xL的抑制作用减少了H3K27M改变的弥漫中线胶质瘤的临床前模型中的肿瘤发生。	Vardon, A.	PDF	N/A	Targeted inhibition of Bcl-xL following radiation reduces tumourigenesis in preclinical models of H3K27M-altered diffuse midline glioma
在皮秒尺度上对CERN-CLEAR-VHEE束的微观结构进行修改，会改变ZFE形态发生，但不会影响过氧化氢的产生。	Kacem, H.	PDF	N/A	Modification of the microstructure of the CERN- CLEAR-VHEE beam at the picosecond scale modifies ZFE morphogenesis but has no impact on hydrogen peroxide production.
解析前列腺癌进展过程中单细胞异质性和细胞生态系统动力学	Zhao, F.	PDF	N/A	Deciphering single-cell heterogeneity and cellular ecosystem dynamics during prostate cancer progression
通过肌肉乙酰胆碱受体结构阐明的自身免疫机制	Li, H.	PDF	N/A	Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures
对果蝇血淋巴细菌感染后的蛋白质组学分析更新	Rommelaere, S.	PDF	N/A	An updated proteomic analysis of Drosophila hemolymph after bacterial infection
多种产甲烷代谢途径的团簇同位素特征	Li, J.	PDF	N/A	The clumped isotope signatures of multiple methanogenesis metabolisms
IVISc-L：一种快速简便的体内检测方法，用于研究基因表达的调控	Som, S.	PDF	N/A	IVISc-L: A quick and simple in vivo assay to study the regulation of gene expression
整合空间转录组学和单核转录组学以绘制发育中小鼠肾脏的基因表达图谱	Chaney, C.	PDF	N/A	Integration of spatial and single nucleus transcriptomics to map gene expression in the developing mouse kidney
PRMT5-剪接轴是调控滞留内含子剪接的关键致癌脆弱点。	Fowler, C. E.	PDF	N/A	The PRMT5-splicing axis is a critical oncogenic vulnerability that regulates detained intron splicing
他汀类药物抑制B7-H3的4Ig异构体的致癌二聚化作用。	Sutton, M. N.	PDF	N/A	Statins inhibit onco-dimerization of the 4Ig isoform of B7-H3
基于硅藻细胞壁的硅藻素驱动遗传工程：对生物硅形态和纳米材料设计的洞察	Qiao, T.	PDF	N/A	Silaffins-Driven Genetic Engineering of Diatom Cell Walls: Insight into Biosilica Morphology and Nanomaterial Design
人类树突棘形态与密度的综合分析：探索人类树突棘的多样性	Schuenemann, K. D.	PDF	N/A	Comprehensive Analysis of Human Dendritic Spine Morphology and Density: Exploring Diversity of Human Dendritic Spines
Munc18-1缺陷型光感受器突触前终末内目标SNARE蛋白的隔离定位	Huang, M.	PDF	N/A	Segregated localization of target-SNARE proteins within presynaptic terminals of Munc18-1 deficient photoreceptors
社交互动感知与心理理论的共同和独特神经相关性	Miao, Z.	PDF	N/A	Common and distinct neural correlates of social interaction perception and theory of mind
单细胞RNA测序用于鉴定源自诱导多能干细胞（iPSC）衍生的少突胶质细胞谱系培养物中的胶质前体亚群	Blaszczyk, G. J.	PDF	N/A	Single Cell RNAseq to identify subpopulations of glial progenitors in iPSC-derived oligodendroglial lineage cultures
前运动皮层血流动力学反映的是内部听觉类别，而非报告的类别。	Boucher, J. E.	PDF	N/A	Premotor cortex hemodynamics reflect internal auditory category, not reported category
神经双域模型用于髓鞘纤维束沿郎飞结的多维电耦合神经冲动传播的多维电耦合	Chun, S.	PDF	N/A	Neural bidomain model for multidimensional ephaptic coupling of neural spike propagation along myelinated fiber bundles with the nodes of Ranvier
野生鼠类中SARS-CoV-2的传染潜力与传播情况	Beissat, K.	PDF	N/A	Infectious potential and circulation of SARS-CoV-2 in wild rats
不同的微生物群落导致甲烷排放对氧气变化产生不同的响应，这些变化发生在多样化的湿地土壤中。	Reji, L.	PDF	N/A	Distinct Microbiomes Underlie Divergent Responses of Methane Emissions from Diverse Wetland soils to Oxygen Shifts
网格蛋白适配体AP-1在植物病原菌灰葡萄孢（Botrytis cinerea）细胞壁完整性和毒力因子分泌中的作用	Calvar, G.	PDF	N/A	Role of the clathrin adaptor AP-1 in cell wall integrity and virulence factor secretion in the plant pathogen Botrytis cinerea
来自湿地和堆肥的戈登氏菌（Gordonia sp.）和节杆菌（Arthrobacter sp.）对聚烯烃的定殖及部分降解	Coughlin, S. A.	PDF	N/A	Polyolefin colonization and partial degradation by Gordonia sp., and Arthrobacter sp. isolated from wetlands and compost
对SARS-CoV-2 nsp16/nsp10介导的2'-O RNA甲基化组装和调控的结构洞察	Misra, A.	PDF	N/A	Structural Insights into the Assembly and Regulation of 2'-O RNA Methylation by SARS-CoV-2 nsp16/nsp10
重组Pichinde报告病毒作为针对高致病性沙粒病毒的高通量抗病毒筛选的安全且合适的替代品	Sacramento, C. Q.	PDF	N/A	Recombinant Pichinde reporter virus as a safe and suitable surrogate for high-throughput antiviral screening against highly pathogenic arenaviruses
自体宿主-病原体配对增强了结核病体外肉芽肿模型中的早期免疫反应和细菌生长控制	Genestet, C.	PDF	N/A	Autologous host-pathogen pairing enhances early immune responses and bacterial growth control in tuberculosis in vitro granuloma model
碱基修饰的核苷酸在细菌中调节免疫信号传导	Zeng, Z.	PDF	N/A	Base-modified nucleotides mediate immune signaling in bacteria
通过肌动蛋白网络，Exportin XPO1动员核抗病毒因子抑制RNA病毒复制。	Sun, B.	PDF	N/A	Mobilization of nuclear antiviral factors by Exportin XPO1 via the actin network inhibits RNA virus replication
建立严格依赖病毒蛋白表达的基孔肯雅病毒假型系统	Tanaka, A.	PDF	N/A	Establishment of a Chikungunya virus pseudotype system strictly dependent on viral protein expression
语言多样性与基因多样性之间存在负相关关系。	Graff, A.	PDF	N/A	An inverse correlation between linguistic and genetic diversity
全球基因混合模式揭示了语言接触的影响。	Graff, A.	PDF	N/A	Global patterns of genetic admixture reveal effects of language contact
对狒狒混合种群的负选择在性染色体X上表现得最为强烈。	Soerensen, E. F.	PDF	N/A	Negative selection on baboon admixture is strongest on chromosome X
综合分析COVID-19多组学数据以发现eQTL，揭示了疾病严重程度的遗传机制	Lee, J.	PDF	N/A	Integrated analysis of COVID-19 multi-omics data for eQTLs reveals genetic mechanisms underlying disease severity
Tiled Amplicon测序技术实现了从临床样本中对病原菌进行无培养的全基因组测序。	Kalinich, C. C.	PDF	N/A	Tiled Amplicon Sequencing Enables Culture-free Whole-Genome Sequencing of Pathogenic Bacteria From Clinical Specimens
自定义选择性过滤器几何形状的钙通道自下而上设计	Liu, Y.	PDF	N/A	Bottom-up design of calcium channels from defined selectivity filter geometry
用于成像细胞内和细胞外钾离子的基因编码红色荧光指示剂	Yang, L.	PDF	N/A	Genetically Encoded Red Fluorescent Indicators for Imaging Intracellular and Extracellular Potassium Ions
T-ALPHA：一种基于分层Transformer的深度神经网络，用于蛋白质-配体结合亲和力预测，并结合不确定性感知的自学习方法以实现蛋白质特异性对齐	Kyro, G. W.	PDF	N/A	T-ALPHA: A Hierarchical Transformer-Based Deep Neural Network for Protein-Ligand Binding Affinity Prediction With Uncertainty-Aware Self-Learning for Protein-Specific Alignment
基于连锁的细菌泛基因组同源基因精炼工具CLARC	Ojeda, I. G.	PDF	N/A	Linkage-based ortholog refinement in bacterial pangenomes with CLARC
草原土壤微生物群的活跃子集会随着土壤深度、水分可用性而变化，并且显著地包括捕食性细菌和兼性共生体。	Penev, P. I.	PDF	N/A	The active subset of grassland soil microbiomes changes with soil depth, water availability and prominently features predatory bacteria and episymbionts
量化表征和预测针对Omicron变种的广谱中和抗体的结合决定因素及免疫逃逸热点：SARS-CoV-2刺突蛋白与抗体复合物的原子级建模	Alshahrani, M.	PDF	N/A	Quantitative Characterization and Prediction of the Binding Determinants and Immune Escape Hotspots for Groups of Broadly Neutralizing Antibodies Against Omicron Variants: Atomistic Modeling of the SARS-CoV-2 Spike Complexes with Antibodies
前颞叶神经元通过声音身份不变性实现识别	Giamundo, M.	PDF	N/A	Voice identity invariance by anterior temporal lobe neurons
功能连接的局部梯度能够在动态发育过程中精确识别婴儿大脑的特征	Yuan, X.	PDF	N/A	Local Gradients of Functional Connectivity Enable Precise Fingerprinting of Infant Brains During Dynamic Development
糖皮质激素作用于新生少突胶质细胞前体细胞，以调节成年海马网络可塑性和应激诱导行为。	Mattioni, L.	PDF	N/A	Glucocorticoids target postnatal oligodendrocyte precursor cells to modulate adult hippocampal network plasticity and stress-induced behavior
NaV1.2和NaV1.6在皮层锥体细胞兴奋性中的不同作用	Garcia, J. D.	PDF	N/A	Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability
LPS 刺激B细胞代谢的动态变化以促进增殖。	Cheung, D. M. S.	PDF	N/A	LPS stimulates dynamic changes in B cell metabolism to promote proliferation
皮肤巨噬细胞中的FABP5介导饱和脂肪引发的IL-1β信号传导，促进肥胖相关银屑病的发展。	Yu, J.	PDF	N/A	FABP5 in Skin Macrophages Mediates Saturated Fat-Induced IL-1β Signaling in Obesity-Associated Psoriasis Development
研究在啮齿动物、非啮齿动物及食蟹猕猴中使用印度尼西亚株病毒的CpG佐剂重组RBD SARS-CoV-2疫苗的免疫原性、功效及安全性	Limeilati, N. A.	PDF	N/A	Study of the immunogenicity, efficacy and safety of recombinant RBD SARS-CoV-2 vaccine with CpG adjuvant in rodent, non-rodent and Maccaca fascicularis using Indonesian Strain Virus
全球红树林沉积物中细菌的生物地理学：基于16S rDNA元条形码的空间模式与生态见解	Jamon-Haon, E.	PDF	N/A	Global Biogeography of Prokaryotes in Mangrove Sediments: Spatial Patterns and Ecological Insights from 16S rDNA Metabarcoding
冷冻电镜结构揭示了松弛体（relaxosome）的结构，这一复合物对细菌交配及抗生素抗性基因的传播至关重要。	Williams, S.	PDF	N/A	Cryo-EM Structure of the relaxosome, a complex essential for bacterial mating and the spread of antibiotic resistance genes
长期护理机构中与养老院获得性肺炎相关的病原体流行率及共存情况	Whealy, R. N.	PDF	N/A	Longitudinal prevalence and co-carriage of pathogens associated with nursing home acquired pneumonia in three long-term care facilities
保守的全球调节因子H-NS对Vibrio fischeri共生体中的生物膜形成具有菌株特异性的影响。	Zarate, D.	PDF	N/A	The conserved global regulator H-NS has a strain-specific impact on biofilm formation in Vibrio fischeri symbionts
产后早期母体向婴儿的质粒传递及其与优势肠道细菌的关联	Kuriyama, Y.	PDF	N/A	Mother-to-infant plasmid transmission in early postpartum and its association with dominant gut bacteria
实时纳米级研究枯草芽孢杆菌孢子衣的组装	Lablaine, A.	PDF	N/A	Real-Time Nanoscale Investigation of Spore Coat Assembly in Bacillus subtilis
一种传递的脱氧核糖核酸酶毒素通过短暂毒害同胞个体，创造了种群的异质性。	Eriksson, H.	PDF	N/A	A delivered DNase toxin creates population heterogeneity through transient intoxication of siblings.
雾化的2-脱氧葡萄糖类似物在先进的体外气道模型中抑制呼吸道病毒感染	Wideman, S. K.	PDF	N/A	Nebulized 2-deoxylated glucose analogues inhibit respiratory viral infection in advanced in vitro airway models
白色念珠菌蛋白质组的综合视图	Gomez Artiguez, L.	PDF	N/A	Candida albicans a comprehensive view of the proteome
化学降解法鉴定出人p38-MAPK是抗击寄生虫感染的宿主靶点	Singhal, J.	PDF	N/A	Chemical degradation identified Human p38-MAPK as a host target to combat parasitic infections
肠道菌群介导的芒果苷向诺拉西醇的转化改变了短链脂肪酸和尿酸代谢	Bunt, D.	PDF	N/A	Gut microbiota-mediated conversion of mangiferin to norathyriol alters short chain fatty acid and urate metabolism
酵母CST和Polα/引物酶复合物协同作用，以确保端粒的正确维持和保护。	Calugaru, K.	PDF	N/A	The yeast CST and Polα/primase complexes act in concert to ensure proper telomere maintenance and protection
一个大型语言模型指导通过组合优化生成的变体抗体的亲和力成熟过程。	Ashraf, F. B.	PDF	N/A	A Large Language Model Guides the Affinity Maturation of Variant Antibodies Generated by Combinatorial Optimization
TEAD促进了腹侧神经祖细胞的谱系进展，与YAP/TAZ无关。	Perry, C. H.	PDF	N/A	TEAD promotes lineage progression of subpallial neural progenitor cells independent of YAP/TAZ
通过不同的抑制性组蛋白甲基化模式定义了不同的层粘连蛋白相关域类。	Martin, C. J.	PDF	N/A	Distinct Classes of Lamin-Associated Domains are Defined by Differential Patterns of Repressive Histone Methylation
三维调控枢纽在胶质母细胞瘤中支持致癌程序	Breves, S. L.	PDF	N/A	Three-dimensional regulatory hubs support oncogenic programs in glioblastoma
沙门氏菌Typhimurium中VI型分泌系统蛋白VgrS的结构	Sachar, K.	PDF	N/A	Structure of the type VI secretion system protein VgrS from Salmonella Typhimurium
在游离DNA片段组学特征上进行有监督的非负矩阵分解，可增强早期癌症检测	Tran, T. H.	PDF	N/A	Supervised non-negative matrix factorization on cell-free DNA fragmentomic features enhances early cancer detection
淀粉样蛋白形成的人溶菌酶中间体通过非天然酰胺-π相互作用得到稳定。	Ahn, M.	PDF	N/A	Amyloid forming human lysozyme intermediates are stabilised by non-native amide-π interactions
水平基因转移和萜类代谢在角苔植物与真菌相互作用中发挥驱动作用	El Mahboubi, K.	PDF	N/A	Horizontal gene transfers and terpene metabolism drive plant-fungal interaction in Marchantia polymorpha
超潮汐河口鱼类生物多样性监测中eDNA捕获方法的表现	Jackman, J. M.	PDF	N/A	Performance of eDNA capture methods for monitoring fish biodiversity in a hyper-tidal estuary
驱动蛋白-1具有高度的柔性，在没有货物的情况下会采取开放的构象。	Smith, E. R.	PDF	N/A	Kinesin-1 is highly flexible and adopts an open conformation in the absence of cargo
利用基于诱导多能干细胞（hiPSC）的模型研究BPDE诱导的胚胎毒性	Meira de Amorim, V. C.	PDF	N/A	Investigating BPDE-induced embryonic toxicity employing hiPSC-based models
APOE4改变了脂滴的蛋白质组，并调节了脂滴的动态变化。	Friday, C. M.	PDF	N/A	APOE4 alters the lipid droplet proteome and modulates droplet dynamics
免疫情绪素在强迫症患者的T细胞和血浆中表现出差异表达。	Blacksell, I. A.	PDF	N/A	Immuno-moodulin is Differentially Expressed in T Cells and Plasma in Obsessive-Compulsive Disorder Patients
IgG的抗炎活性需要I型和II型Fc受体的共同参与。	Jones, A. T.	PDF	N/A	The anti-inflammatory activity of IgG requires the co-engagement of types I and II Fc receptors
小鼠2型先天淋巴细胞的免疫代谢分析：一种稳健的逐步方法	Krisna, S. S.	PDF	N/A	Immunometabolic analysis of primary murine Group 2 Innate Lymphoid Cells: a robust step-by-step approach
从头设计和结构化一个以肽为中心的TCR模拟结合模块	Householder, K. D.	PDF	N/A	De novo design and structure of a peptide-centric TCR mimic binding module
二维类器官展示了寄生线虫及其分泌产物在肠道上皮基底或顶端相互作用的特异性。	White, R.	PDF	N/A	2-D organoids demonstrate specificity in the interactions of parasitic nematodes and their secreted products at the basal or apical intestinal epithelium
无需生态位指令、反馈或微调的自我更新	MacArthur, B.	PDF	N/A	Self-renewal without niche instruction, feedback or fine-tuning
流感病毒A触发的细胞间钙波传播在促进感染中的关键作用	Kozawa, F.	PDF	N/A	The crucial role of intercellular calcium wave propagation triggered by influenza A virus in promoting infection
野鸟，尤其是候鸟，在北美地区密集传播H5N1病毒，导致其迅速地理扩散并反复溢出到农业领域。	Damodaran, L.	PDF	N/A	Intensive transmission in wild, migratory birds drove rapid geographic dissemination and repeated spillovers of H5N1 into agriculture in North America
一个用于估计重要农业病害系统中媒介传播和疾病扩散的建模框架	Preedy, K. F.	PDF	N/A	A modelling framework to estimate vector dispersal and disease spread in an important agricultural pathosystem
空间系统发育学与连续数据：加利福尼亚苔藓植物的应用研究	Kling, M. M.	PDF	N/A	Spatial Phylogenetics with Continuous Data: an Application to California Bryophytes
基因调控网络推断与联合表示：图神经网络与单细胞基础模型的结合	Kommu, S.	PDF	N/A	Gene Regulatory Network Inference with Joint Representation from Graph Neural Network and Single-Cell Foundation Model
非洲各地dhfr和dhps基因上磺胺多辛和乙胺嘧啶抗性等位基因和单倍型的不同共进化及流行	White, N. F. D.	PDF	N/A	Disparate co-evolution and prevalence of sulfadoxine and pyrimethamine resistance alleles and haplotypes at dhfr and dhps genes across Africa
清道夫受体CD163通过多聚化来摄取多种配体。	Zhou, R. X.	PDF	N/A	Scavenger receptor CD163 multimerises to allow uptake of diverse ligands
UBR4复合体的结构，作为真核蛋白质质量控制的核心E4连接酶	Grabarczyk, D. B.	PDF	N/A	Architecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control
用于三色RNA成像的正交RNA调控降解结构域，具有最小RNA干扰	Wu, J.	PDF	N/A	Orthogonal RNA-regulated destabilization domains for three-color RNA imaging with minimal RNA perturbation
含焦磷酸盐的磷酸钙对异位骨质量有负面影响	Jolic, M.	PDF	N/A	Pyrophosphate-containing Calcium Phosphates Negatively Impact Heterotopic Bone Quality
制剂、表征及体内免疫原性研究：新型VLP疫苗热稳定可溶性微针的研制	Muttil, P.	PDF	N/A	Formulation, Characterization, and in vivo Immunogenicity of Heat-Stabilized Dissolvable Microneedles Containing a Novel VLP Vaccine
使水凝胶涂层在硅胶乳房假体上与聚（醋酸乙烯酯）底漆层	Stanger, K.	PDF	N/A	Enabling Hydrogel Coating on Silicone Breast Implants with Poly(Vinyl Acetate) Primer Layer
通过MutaT7实现的与生长耦合的连续定向进化，实现了高效且自动化的酶工程。	Deng, Y.	PDF	N/A	Growth-coupled continuous directed evolution by MutaT7 enables efficient and automated enzyme engineering
时间参数决定迷走神经刺激引导神经可塑性的效果	Addo, J. J. A.	PDF	N/A	Temporal Parameters Determine the Efficacy of Vagus Nerve Stimulation Directed Neural Plasticity
揭示潜力：细菌微室壳蛋白的光捕获与半导体特性	Bedi, S.	PDF	N/A	Illuminating the Potential: Light Harvesting and Semiconducting Properties of Bacterial Microcompartment Shell Proteins
CCGM：一种用于增强化学型探索、注释和筛选的复合粗粒度模型表示法	Sahni, N.	PDF	N/A	CCGM: a Compound Coarse Grain Model representation for enhanced chemotype exploration, annotation and screening
ScHiCAtt：利用基于注意力模型的方法提升单细胞Hi-C分辨率	Menon, R.	PDF	N/A	ScHiCAtt: Enhancing Single-Cell Hi-C Resolution Using Attention-Based Models
捕捉HSPB1分子伴侣寡聚体在原子分辨率下的构象异质性	Berkeley, R. F.	PDF	N/A	Capturing the Conformational Heterogeneity of HSPB1 Chaperone Oligomers at Atomic Resolution
细胞间通讯控制了类原肠胚对称性破缺的时机	Oriola, D.	PDF	N/A	Cell-cell communication controls the timing of gastruloid symmetry-breaking
一种用于可逆光学控制外周镇痛的阿片类药物疗效转换	Posa, L.	PDF	N/A	An opioid efficacy switch for reversible optical control of peripheral analgesia
胚胎暴露于阻燃剂四溴双酚A（TBBPA）会破坏斑马鱼的背腹模式形成。	Senarath Pathirajage, K.	PDF	N/A	Embryonic exposures to flame retardant tetrabromobisphenol A (TBBPA) disrupts dorsoventral patterning in zebrafish
通过计算机模拟发现针对MEIG1-PACRG复合物的潜在抑制剂，用于男性避孕药物的开发	Hasse, T. A.	PDF	N/A	In silico discovery of potential inhibitors targeting the MEIG1-PACRG complex for male contraceptive development
IL-17A 对早期祖细胞群体进行预处理，以调节红细胞生成的反馈回路。	Wu, Q. C.	PDF	N/A	IL-17A primes an early progenitor compartment to tune the erythropoietic feedback circuit
融合跨通道和时间的多感官信号	Anil, S.	PDF	N/A	Fusing multisensory signals across channels and time
利用人工智能分类和预处理技术，通过直接冷冻电子断层扫描检测天然SNARE和Munc13蛋白桥	Orozco-Borunda, D. H.	PDF	N/A	Direct cryo-ET detection of native SNARE and Munc13 protein bridges using AI classification and preprocessing
BACH2驱动的组织驻留记忆程序促进HIV-1持久性	Wei, Y.	PDF	N/A	BACH2-driven tissue resident memory programs promote HIV-1 persistence
不同脂质体配方的5-氟尿嘧啶会导致胃肠道毒性的变化。	Thorpe, D. W.	PDF	N/A	Different liposomal formulations of 5-Fluorouracil result in variations to gastrointestinal toxicities
基于模拟的近亲标记重捕推断：对小规模种群和非随机交配的启示	Conn, P. B.	PDF	N/A	Simulation-based inference for close-kin mark-recapture: implications for small populations and nonrandom mating
预测巨藻修复对食物网和渔业生产的影响	O'Neill, T.	PDF	N/A	Predicting the impact of giant kelp restoration on food webs and fisheries production
血吸虫杂交种的转录组可塑性可能有助于其人兽共患潜力。	Toulza, E.	PDF	N/A	Transcriptomic plasticity in hybrid schistosomes can contribute to their zoonotic potential
分离到一株能够降解截短侧耳素泰妙菌素的鞘氨醇单胞菌新菌株：组学分析揭示其转化途径	Perruchon, C.	PDF	N/A	Isolation of a novel Sphingomonas strain able to degrade the pleuromutilin tiamulin: omic analysis reveals its transformation pathway
时间分辨荧光蛋白在时间和光谱域荧光显微镜中的应用	Tan, Z.	PDF	N/A	Time-resolved fluorescent proteins towards fluorescence microscopy in the temporal and spectral domains
一个可推广的染色质结构基础模型，适用于跨物种的单细胞和多组学分析	Wang, X.	PDF	N/A	A generalizable Hi-C foundation model for chromatin architecture, single-cell and multi-omics analysis across species
蛋白酶体激活剂PA200调控肿瘤细胞侵袭	Yazgili, A. S.	PDF	N/A	The proteasome activator PA200 regulates tumor cell invasion
GRN建模器：一种直观构建和评估基因调控网络的工具及其在振荡器和光生物传感器中的应用	Hollo, G.	PDF	N/A	GRN modeler: An Intuitive Tool for Constructing and Evaluating Gene Regulatory Networks and its Applications to Oscillators and a Light Biosensor
亚基类型、选择性剪接和辅助蛋白对AMPA受体转运的影响	Couch, T.	PDF	N/A	The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking
前额叶伽马振荡和恐惧消退学习需要早期新生期的中间神经元-少突胶质细胞间的交流。	Plaisier, F.	PDF	N/A	Prefrontal gamma oscillations and fear extinction learning require early postnatal interneuron-oligodendroglia communication
转基因线在斑马鱼幼体中标记网状脊髓神经元的特性分析	Collins, E. M.	PDF	N/A	Characterisation of transgenic lines labelling reticulospinal neurons in larval zebrafish
PPARδ通过限制CIITA-MHC II的表达，抑制了肿瘤内Treg细胞的抑制功能。	Yang, Q.	PDF	N/A	PPARδ restrains the suppression function of intra-tumoral Tregs by limiting CIITA-MHC II expression
AMPK通过消除免疫屏障，促进CD8+ T细胞介导的针对肝细胞癌的免疫反应。	Hu, H.-H.	PDF	N/A	AMPK acts to remove immune barriers to CD8+ T cell-mediated immunity against hepatocellular carcinoma
鉴定调控多形拟杆菌生物膜形成的菌株特异性信号	Glowacki, R. W. P.	PDF	N/A	Identification of strain-specific cues that regulate biofilm formation in Bacteroides thetaiotaomicron
一个全面的基准测试，针对具有广泛靶向范围的多款高效基础编辑器	Wang, X.	PDF	N/A	A comprehensive benchmark for multiple highly efficient base editors with broad targeting scope
使用RNA-seq研究犬弓蛔虫幼虫在体外暴露于大环内酯类药物后的转录反应	Quintana, T. A.	PDF	N/A	Transcriptional responses to in vitro macrocyclic lactone exposure in Toxocara canis larvae using RNA-seq
左右大脑皮层相互作用驱动纤毛虫四膜虫的细胞内模式形成	Lee, C.	PDF	N/A	Left-right cortical interactions drive intracellular pattern formation in the ciliate Tetrahymena
特定物种的氧气感应控制着脊椎动物肢体再生的启动	Tsissios, G.	PDF	N/A	Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration
嗅觉丧失会降低毛虫的性能并增加对天敌的易感性。	Wang, Q.	PDF	N/A	Loss of olfaction reduces caterpillar performance and increases susceptibility to a natural enemy
珊瑚Acropora loripes组织内Endozoicomonas的不同聚集模式	Gotze, C. R.	PDF	N/A	Differential aggregation patterns of Endozoicomonas within tissues of the coral Acropora loripes
在私人信息和社会信息获取成本下分散策略的演化	Sion, A.	PDF	N/A	On the evolution of dispersal strategies under the costs of acquisition of private and social information
利用环境DNA宏基因组学提升整体生物多样性监测与发现	Curto, M. A. C.	PDF	N/A	Improving whole biodiversity monitoring and discovery with environmental DNA metagenomics
自然草地的多样性和生产力随着全球变化因素数量的增加而下降。	Wang, J.	PDF	N/A	Diversity and productivity of a natural grassland decline with the number of global change factors
活性氧和抗氧化剂在塑造按蚊生命史及寄生虫耐受性中的作用	Zeferino, T. G.	PDF	N/A	The role of prooxidants and antioxidants in shaping life-history and parasite tolerance in Anopheles mosquitoes
染色质相关蛋白全基因组共占据的比较图谱	White, S. M.	PDF	N/A	Comparative atlas of genome-wide chromatin-associated protein co-occupancy
评估全基因组加倍对蛛形纲动物发育过程中基因表达和调控的影响	Aase-Remedios, M. E.	PDF	N/A	Assessing the impact of whole genome duplication on gene expression and regulation during arachnid development
父母的排斥行为与猫头鹰猴的生存能力下降、行为改变以及miRNAs的代际遗传有关。	Farinha, J.	PDF	N/A	Parental rejection is associated with intergenerational inheritance of reduced survival, altered behaviours and miRNAs in Owl Monkeys
解码家禽发声 - 自然语言处理与转换模型用于语义和情感分析	Manikandan, V.	PDF	N/A	Decoding Poultry Vocalizations - Natural Language Processing and Transformer Models for Semantic and Emotional Analysis
一个用于生成多维3D对象并具有精细控制特征空间的工具箱：Quaddle 2.0	Wen, X.	PDF	N/A	A Toolbox for Generating Multidimensional 3-D Objects with Fine-Controlled Feature Space: Quaddle 2.0
觅食的熊蜂在采花时的个体间差异性	Armand, M.	PDF	N/A	Interindividual variability in flower pickiness by foraging bumblebees
同位素标记和数据非依赖性采集作为在Orbitrap Astral质谱仪上进行蛋白质组学分析的互补策略	Liu, X.	PDF	N/A	Isobaric Tagging and Data Independent Acquisition as Complementary Strategies for Proteome Profiling on an Orbitrap Astral Mass Spectrometer
小分子激活肿瘤抑制激酶LKB1	Kretschmer, L. S.	PDF	N/A	Small molecule activation of the tumor suppressor kinase LKB1
血清分离的细胞外囊泡对聚焦超声血脑屏障开放的响应	Kline-Schoder, A. R.	PDF	N/A	Response of Serum-isolated Extracellular Vesicles to Focused Ultrasound Blood-Brain Barrier Opening
脂质纳米颗粒条形码技术用于多重单细胞RNA测序	Feng, Y.	PDF	N/A	Lipid Nanoparticle Barcoding for Multiplexed Single-Cell RNA Sequencing
OPUS-GO：一种基于生物语言模型的可解释蛋白质/RNA序列注释框架	Xu, G.	PDF	N/A	OPUS-GO: An interpretable protein/RNA sequence annotation framework based on biological language model
通过样本特异性建模误差率实现低频体细胞突变的精确识别	Lin, Y.	PDF	N/A	Accurate calling of low-frequency somatic mutations by sample-specific modeling of error rates
使用下一代蛋白质测序（NGPS）检测氨基酸变异	Chinnaraj, M.	PDF	N/A	Detecting Amino Acid Variants Using Next-Generation Protein Sequencing (NGPS)
一个通用且多功能的框架，用于训练和评估自编码器，应用于生物表示学习及其他领域：AUTOENCODIX	Joas, M.	PDF	N/A	A generalized and versatile framework to train and evaluate autoencoders for biological representation learning and beyond: AUTOENCODIX
基于通路富集的无监督学习方法在胰腺导管癌中识别出癌症相关成纤维细胞的新亚型	Ai, H.	PDF	N/A	Pathway enrichment-based unsupervised learning identifies novel subtypes of cancer-associated fibroblasts in pancreatic ductal carcinoma
基于优化的健康饮食建议	Wang, X.-W.	PDF	N/A	Optimization-based dietary recommendations for healthy eating
健身转移：通过基于生物学的数据增强提高变异效应预测	Mialland, A.	PDF	N/A	Fitness translocation: improving variant effect prediction with biologically-grounded data augmentation
HAIRpred：从抗原一级结构预测与人类抗体相互作用残基	Sahni, R.	PDF	N/A	HAIRpred: Prediction of human antibody interacting residues in an antigen from its primary structure
使用深度卷积神经网络预测基因表达及DNA结合位点的定位	Karshenas, A.	PDF	N/A	Predictive Modeling of Gene Expression and Localization of DNA Binding Site Using Deep Convolutional Neural Networks
体外口腔内含片的崩解	Pham, Q. D.	PDF	N/A	In vitro disintegration of lozenge in oral cavity
通过随机物理模型和机器学习来表征活体成像中的粒子动力学	Nardi, G.	PDF	N/A	Characterizing particle dynamics in live imaging through stochastic physical models and machine learning
细胞命运决策模型的全局稳定性与临界点预测	Xu, L.	PDF	N/A	Global Stability and Tipping Point Prediction of the cell fate decision making model
与癌症相关的ERBB4突变具有转化能力，并使肿瘤对靶向治疗产生耐药性。	Ojala, V. K.	PDF	N/A	Recurrent cancer-associated ERBB4 mutations are transforming and confer resistance to targeted therapies
伯基特淋巴瘤中的应激诱导信号通路在生发中心来源的B淋巴瘤的命运决定和发病机制中发挥了新型机制的作用。	Gothwal, S. K.	PDF	N/A	Stress Induced Signaling Pathways in Burkitt Lymphoma Play Novel Mechanisms in Fate Determination and Pathogenesis of Germinal Center-Derived B-Lymphomas
维京地区的杂草：在冻原草地中干扰优势禾草对杂草繁殖的影响。	Celis, G.	PDF	N/A	Forbs in Viking lands: The effect of disturbing dominant graminoids on forb recruitment in tundra grasslands.
莲属日本种VIH2是一种肌醇焦磷酸合酶，能够调控丛枝菌根。	Raj, K.	PDF	N/A	Lotus japonicus VIH2 is an inositol pyrophosphate synthase that regulates arbuscular mycorrhiza
FvM4K1是一种丝氨酸/苏氨酸激酶，也是Ste20同源物，通过Hippo信号通路正向调控林地草莓（Fragaria vesca）的果实大小。	Qi, B.	PDF	N/A	FvM4K1, a Serine/Threonine Kinase and Ste20 Homolog Positively Regulates Fruit Size via Hippo Signalling Pathway in Woodland Strawberry (Fragaria vesca)
拟南芥RMR蛋白的RING指结构域作为E3连接酶，在反式高尔基体运输过程中起着至关重要的作用。	Chen, S.	PDF	N/A	The RING-finger domain of Arabidopsis RMR functions as an E3 ligase essential for post-Golgi trafficking
间作对欧洲大豆和玉米自给自足具有高潜力贡献	Chen, M.	PDF	N/A	High potential contribution of intercropping to soybean and maize self-sufficiency in Europe
调控逻辑类别的选择会调节随机布尔网络中的动力学状态	Sil, P.	PDF	N/A	Choices of regulatory logic class modulate the dynamical regime in random Boolean networks
视网膜药物输送的数学模型	Roberts, P. A.	PDF	N/A	Mathematical Models of Retinal Drug Delivery
DeepMapper：基于注意力机制的自编码器用于伤口愈合中的系统识别与阶段预测	Lu, F.	PDF	N/A	DeepMapper: Attention-Based AutoEncoder for System Identification in Wound Healing and Stage Prediction
任务和行为相关变量在非空间联想学习过程中由后鼻皮层和内侧内嗅皮层编码	Nystuen, I. N.	PDF	N/A	Task and Behavior-Related Variables Are Encoded by the Postrhinal and Medial Entorhinal Cortex During Non-Spatial Associative Learning
使用catFISH技术捕捉对社会等级中主导和从属成员的动态神经元反应	Dwortz, M. F.	PDF	N/A	Capturing Dynamic Neuronal Responses to Dominant and Subordinate Social Hierarchy Members with catFISH
轴-轴突抑制理论	Brette, R.	PDF	N/A	Theory of axo-axonic inhibition
关键时期支持皮质处理模型中的表征学习。	Wu, Z.	PDF	N/A	Critical periods support representation learning in a model of cortical processing
在手部伸向目标时，未能完全适应表面运动	Balestrucci, P.	PDF	N/A	Incomplete adaptation to surface movement during hand reaching
小脑类器官在人类小脑发育过程中模拟细胞类型特异性的FOXP2表达	Apsley, E. J.	PDF	N/A	Cerebellar organoids model cell type-specific FOXP2 expression during human cerebellar development
人工具身电路揭示脊椎动物视动行为中的神经结构	Liu, X.	PDF	N/A	Artificial Embodied Circuits Uncover Neural Architectures of Vertebrate Visuomotor Behaviors
在轻度围产期缺氧-缺血后数周内持续损失可存活神经元	McNally, M.	PDF	N/A	Ongoing loss of viable neurons for weeks after mild perinatal hypoxia-ischemia
一种用于经颅电流传导的无引导场优化框架	Weise, K.	PDF	N/A	A Leadfield-Free Optimization Framework for Transcranially Applied Electric Currents
一种基于FRET的FLIM方法用于研究膜诱导的神经元中α-突触核蛋白聚集	Ivey, P. M. E.	PDF	N/A	A FRET-Based FLIM Method to Probe Membrane-Induced Alpha-Synuclein Aggregation in Neurons
小鼠耳蜗外毛细胞在机械转导受损情况下的紧张性声音诱发运动	Dewey, J. B.	PDF	N/A	Tonic sound-evoked motility of cochlear outer hair cells in mice with impaired mechanotransduction
时间掩蔽信号和空间掩蔽信号在感知连续视觉事件中的贡献	Buonocore, A.	PDF	N/A	Contributions of temporal and spatial masking signals in perception of sequential visual events
通过可塑性实现稳定性：通过表征漂移寻找稳定的记忆	Natrajan, M.	PDF	N/A	Stability through plasticity: Finding robust memories through representational drift
月经周期中皮质和视网膜血流的内分泌调节	Wright, M. E.	PDF	N/A	Endocrine modulation of cortical and retinal blood flow across the menstrual cycle
通过单细胞转录组研究的元分析揭示帕金森病中的性别差异	Gordillo-Gonzalez, F.	PDF	N/A	Uncovering sex differences in Parkinson's Disease through metaanalysis of single cell transcriptomic studies
Neddylation调控兴奋性神经元的发育与功能	Torres, J.	PDF	N/A	Neddylation regulates the development and function of excitatory neurons
在癫痫发生过程中对TrkB-FL受体裂解的研究：来自海人酸诱导的癫痫模型及人类样本的见解	Ribeiro-Rodrigues, L.	PDF	N/A	Cleavage of the TrkB-FL Receptor During Epileptogenesis: Insights from a Kainic Acid-Induced Model of Epilepsy and Human Samples
识别调控疼痛引发睡眠障碍的大脑回路	Lynch, N.	PDF	N/A	Identifying the Brain Circuits that Regulate Pain-Induced Sleep Disturbances
斑马鱼功能性脑网络的结构和遗传决定因素	Legare, A.	PDF	N/A	Structural and genetic determinants of zebrafish functional brain networks
使用MEG测量颜色表征的时间演变揭示了“从粗略到精细”的动态过程。	Goddard, E.	PDF	N/A	Temporal evolution of color representations measured with MEG reveals a 'coarse to fine' dynamic
在听力阈值正常的年轻成人中，听觉脑干反应、认知能力与噪音中语音感知之间的关系	DiNino, M.	PDF	N/A	The relationship between auditory brainstem responses, cognitive ability, and speech-in-noise perception among young adults with normal hearing thresholds
即用型MHC-I纳米颗粒，用于高通量T细胞筛选研究	Phan, H. A. T.	PDF	N/A	Ready-to-load MHC-I Nanoparticles for High-throughput T cell Screening Studies
对接受生育治疗的女性卵泡液中的小细胞外囊泡进行单颗粒分析，揭示了独特的PD-L1+群体	Bortot, B.	PDF	N/A	Single-particle analysis of small extracellular vesicles from the follicular fluid of women undergoing fertility treatments reveals distinct PD-L1+ populations
有袋类动物的肢体模式重塑了侧板中胚层细分对于肢体形成的必要性。	Newton, A. H.	PDF	N/A	Marsupial limb patterning redefines the necessity of lateral plate mesoderm subdivision for limb formation
Cxcl12a信号的局部激活调控斑马鱼胚胎中嗅基板的形态发生	Zilliox, M.	PDF	N/A	Local activation of Cxcl12a signaling controls olfactory placode morphogenesis in zebrafish embryos
Kcnb1-Kcng4轴调控Scospondin分泌及Reissner纤维的发育	Amini, R.	PDF	N/A	Kcnb1-Kcng4 axis regulates Scospondin secretion and Reissner fiber development
沉默的储主正在塑造疾病的出现：荷兰乌苏图病毒的案例	de Wit, M. M.	PDF	N/A	Silent reservoirs are shaping disease emergence: the case of Usutu virus in the Netherlands
全球珊瑚礁生态系统的稳定性与临界点预测	Xu, L.	PDF	N/A	Global Stability and Tipping Point Prediction of the Coral Reef Ecosystem
两种地理上共存的真菌种植蚂蚁的饲料偏好：一种饮食DNA方法	Richards-Perhatch, M.	PDF	N/A	Forage preference in two geographically co-occurring fungus gardening ants: a dietary DNA approach
失传126年：土著知识与相机陷阱记录下极度濒危的黑枕雉鸽（Otidiphaps insularis）	Gregg, J. J.	PDF	N/A	Lost to science for 126 years: Indigenous Knowledge and Camera Trapping Document the Critically Endangered Black-Naped Pheasant-Pigeon Otidiphaps insularis
净化选择塑造了P因子在果蝇群体中入侵的动态	Langmüller, A. M.	PDF	N/A	Purifying Selection Shapes the Dynamics of P-element Invasion in Drosophila Populations
基因组基础模型：预训练并不保证性能	Vishniakov, K.	PDF	N/A	Genomic Foundationless Models: Pretraining Does Not Promise Performance
雄激素刺激迅速重塑了前列腺癌中时间性的3D基因组和表观基因组状态，以触发AR介导的转录。	Campbell, E. M.	PDF	N/A	Androgen stimulation rapidly reorganizes temporal 3D genome and epigenome states to trigger AR-mediated transcription in prostate cancer.
染色质可及性分类揭示了TAD边界的新型结构蛋白	Jacome-Lopez, K.	PDF	N/A	Chromatin accessibility classification of TAD boundaries discloses new architectural proteins
通过表观基因组和转录分析揭示的独特黑质和皮层通路：在罗藤酮诱导的帕金森病大鼠模型中的研究	Tsalenchuk, M.	PDF	N/A	Unique nigral and cortical pathways implicated by epigenomic and transcriptional analyses in a rotenone rat model of Parkinson's disease
脱氨酶介导的染色质可及性分析，具有单等位基因分辨率	Yu, T.	PDF	N/A	Deaminase-mediated chromatin accessibility profiling with single-allele resolution
HieVi：基于蛋白质组学的噬菌体聚类的蛋白质大型语言模型	Panigrahi, S.	PDF	N/A	HieVi: Protein Large Language Model for proteome-based phage clustering
基于MHC-IIB差异的性别特异性择偶和配偶更换在一种遗传上实行一夫一妻制的海鸟中	Thel, L.	PDF	N/A	Sex-specific mate choice and mate change based on MHC-IIB dissimilarity in a genetically monogamous seabird
用于伤口愈合的无线生物电子设备	Baniya, P.	PDF	N/A	Wireless bioelectronic device for wound healing
Venomics AI：利用计算方法探索全球毒液以发现抗生素	Guan, C.	PDF	N/A	Venomics AI: a computational exploration of global venoms for antibiotic discovery
均匀原位交联水凝胶包裹高密度人癌细胞促进体内血管化肿瘤模型构建，用于免疫细胞治疗	Huang, Z.	PDF	N/A	Homogeneously crosslinked in situ hydrogel enclosing high-density human-cancer cells promotes vascularized in vivo tumor modeling for immune cell therapy
衰老过程中肌腱内葡萄糖和谷氨酰胺代谢的协调性丧失	Mlawer, S. J.	PDF	N/A	Coordination of Glucose and Glutamine Metabolism in Tendon is Lost in Aging
一个低成本的无标记运动捕捉系统，用于自动化功能性步态评估：可行性研究	Darici, O.	PDF	N/A	A Low-Cost Markerless motion capture system to automate Functional Gait Assessment: Feasibility Study
一种用于预测蛋白质内在无序区域相互作用的深度学习方法	Majila, K.	PDF	N/A	A deep learning method for predicting interactions for intrinsically disordered regions of proteins
分类领域，基准测试GPT-4，葡萄牙语医疗AI问答数据集	Matsuoka, F. A.	PDF	N/A	Classifying Domains, Benchmarking GPT-4, A Portuguese Dataset for Medical AI Q&A
基于进化信息的3D基序预测框架下的全合一RNA折叠	Karan, A.	PDF	N/A	All-at-once RNA folding with 3D motif prediction framed by evolutionary information
零样本保留时间预测：利用分子结构编码对未见过的翻译后修饰进行预测	Dens, C.	PDF	N/A	Zero-shot retention time prediction for unseen post-translational modifications with molecular structure encodings
超快冷冻电子显微镜（cryo-UEM）中软物质的辐射损伤行为	Zhao, Y.	PDF	N/A	Radiation damage behavior of soft matter in ultrafast cryo-electron microscopy (cryo-UEM)
利用新型转录组化学图谱个性化选择化疗药物	Lin-Rahardja, K.	PDF	N/A	Personalizing chemotherapy drug selection using a novel transcriptomic chemogram
通过核磁共振（NMR）测定的高分子量透明质酸的分子灵活性对癌细胞的侵袭具有深远的影响。	Bashtanova, U.	PDF	N/A	Molecular flexibility of high molecular weight hyaluronic acid measured by NMR has a profound effect on invasion of cancer cells
氘强化多不饱和脂肪酸可保护小鼠免受1型糖尿病引起的肌肉萎缩。	Eshima, H.	PDF	N/A	Deuterium-reinforced polyunsaturated fatty acids protect against muscle atrophy induced by type 1 diabetes in mice
参与秀丽隐杆线虫有害光感觉的神经元和分子	Dunkel, E.	PDF	N/A	Neurons and molecules involved in noxious light sensation in Caenorhabditis elegans
直立姿势在不同姿态下都接近临界稳定性进行控制	Geng, Y.	PDF	N/A	Upright stance is controlled close to critical stability across different postures
精密抓握研究是否延伸至无约束、多指抓握？	Lepori, F.	PDF	N/A	Does Precision Grip Research Extend to Unconstrained, Multidigit Grasping?
通过结合神经表示法将项目与情境绑定，使用位置记忆法	Huang, J.	PDF	N/A	Binding items to contexts through conjunctive neural representations with the Method of Loci
MNK1和MNK2在社会和认知行为中发挥着独特的作用，这通过激酶特异性调节突触蛋白质组和磷酸蛋白质组来实现。	Proce, R. O.	PDF	N/A	Distinct roles for MNK1 and MNK2 in social and cognitive behavior through kinase-specific regulation of the synaptic proteome and phosphoproteome
异常的神经元同步与啮齿动物模型中儿童颅部放射治疗引起的认知缺陷相关	Barrientos, S. A.	PDF	N/A	Aberrant Neuronal Synchronization Associated with Cognitive Deficits in a Rodent Model of Childhood Cranial Irradiation
人类皮肤中睡眠状态伤害感受器的分子结构	Koerner, J.	PDF	N/A	Molecular architecture of human dermal sleeping nociceptors
石墨烯神经探针揭示了与同步状态相关的大规模细胞外电位的超慢动态	Garcia-Cortadella, R.	PDF	N/A	Large-scale infra-slow dynamics of extracellular potentials linked to synchronous states revealed by graphene neural probes
瞬时感受器电位香草酸受体通道2（Transient receptor potential vanilloid channel 2）参与了多模式的细胞内质网和核周空间的扩张，这种扩张现象同样可以在朊病毒感染的小鼠中观察到。	Zhao, W.	PDF	N/A	Transient receptor potential vanilloid channel 2 contributes to multi-modal endoplasmic reticulum and perinuclear space dilations that can also be observed in prion-infected mice
使用信息解码技术在皮层中表征色调和饱和度的特征	Rozman, A.	PDF	N/A	CHARACTERISING REPRESENTATIONS OF HUE AND SATURATION IN THE CORTEX USING INFORMATION DECODING
频率标记的fMRI：一种用于精细时空分析皮层功能的平台	Ngo, G. N.	PDF	N/A	Frequency-tagged fMRI: A platform for fine-grained spatiotemporal analysis of cortical function
使用可解释的机器学习方法可视化功能性网络连接差异	Sendi, M. S. E.	PDF	N/A	Visualizing Functional Network Connectivity Differences Using an Explainable Machine-learning Method
中高剂量DMT的时间分辨神经和体验动力学	Lewis-Healey, E.	PDF	N/A	Time-resolved neural and experience dynamics of medium- and high-dose DMT
朝向实现和解释掩蔽独立成分分析，以识别静息状态下BOLD fMRI脑干中的自主激活特征	Miedema, M. E.	PDF	N/A	Towards the implementation and interpretation of masked ICA for identifying signatures of autonomic activation in the brainstem with resting-state BOLD fMRI
觉醒过程中慢波活动的电路级动力学及其传播	Pazienti, A.	PDF	N/A	Circuit-Level Dynamics of Slow Wave Activity and Propagation During the Awakening Process
单次剂量后数周，迷幻药增强灵活学习能力	Brouns, E. J.	PDF	N/A	Psychedelic enhancement of flexible learning weeks after a single dose
在力场运动学习中，陈述性记忆对快速和慢速适应过程的在线干扰	Rudolph, J. L.	PDF	N/A	Online interference of declarative memory on fast and slow adaptive processes in force field motor learning
神经元脂肪酸氧化在强化学习后为记忆提供能量	Pavlowsky, A.	PDF	N/A	Neuronal fatty acid oxidation fuels memory after intensive learning
细胞类型转录特征在体外培养的人脑组织中得以维持。	McGinnis, J.	PDF	N/A	Cell type transcriptional identities are maintained in cultured ex vivo human brain tissue
小鼠初级视皮层中能量高效编码的时间动态	Moosavi, S. A.	PDF	N/A	Temporal dynamics of energy-efficient coding in mouse primary visual cortex
重组B3型肠道病毒D68株系能够在293T细胞中高效复制，并感染人脊髓类器官。	Jones, J. E.	PDF	N/A	Recombinant B3 clade enterovirus D68 strains are efficiently rescued in 293T cells and infect human spinal cord organoids.
输卵管上皮单细胞转录组模型的构建揭示了细胞特化、新的分化轨迹以及与异位妊娠相关的基因网络关联	Wright, L. I.	PDF	N/A	Single Cell Transcriptomic Modelling of the Fallopian Tube Epithelium Identifies Cellular Specialisation, Novel Differentiation Trajectories, and Gene Network Associations with Ectopic Pregnancy
大象数量增加对树木异速生长的影响	Thel, L.	PDF	N/A	The effect of an increasing elephant population on the allometry of trees
利用温度依赖型物候模型，为寄生蜂Dolichogenidea gelechiidivoris (Marsh) 进行Tuta absoluta (Meyrick) 的生物防治，绘制适宜释放区域图。	Mujica, N. C.	PDF	N/A	Mapping of suitable release areas for the parasitoid Dolichogenidea gelechiidivoris (Marsh) for the classical biocontrol of Tuta absoluta (Meyrick) using temperature-dependent phenology models
基因年龄塑造了果蝇精液蛋白质组的功能和进化特性。	Ranz, J. M.	PDF	N/A	Gene age shapes functional and evolutionary properties of the Drosophila seminal fluid proteome
结构酶学、系统发育学、分化作用与生物学初期的符号反思	carter, c. W.	PDF	N/A	Structural Enzymology, Phylogenetics, Differentiation, and Symbolic Reflexivity at the Dawn of Biology
城市化对昼夜活动的时间和变异性的影响因雀形目鸟类物种和季节而异。	Capilla-Lasheras, P.	PDF	N/A	Urban effects on timing and variability of diel activity differ across passerine species and seasons
基于机器学习和实验验证，识别与支链氨基酸相关基因的HIRI潜在特征基因和免疫细胞浸润	Zhao, J.	PDF	N/A	ldentify potential feature genes and immune cell infiltration of HIRI based on branched-chain amino acid-related genes by machine learning and experimental validation
mitoXplorer 3.0，一个用于探索单细胞RNA测序数据中线粒体动态的网络工具。	Haering, M.	PDF	N/A	mitoXplorer 3.0, a web tool for exploring mitochondrial dynamics in single-cell RNA-seq data.
空间-DC：一种基于深度学习的稳健方法，用于空间蛋白质组学的反卷积	Yao, J.	PDF	N/A	Spatial-DC: a robust deep learning-based method for deconvolution of spatial proteomics
一个用于自主AI驱动药物发现的框架	Selinger, D. W.	PDF	N/A	A Framework for Autonomous AI-Driven Drug Discovery
心脏起搏细胞利用随机共振确保在接近窦性停搏的低速率下实现故障安全操作	Okamura, A.	PDF	N/A	Cardiac Pacemaker Cells Harness Stochastic Resonance to Ensure Fail-Safe Operation at Low Rates Bordering on Sinus Arrest
心脏场特异性心肌细胞分化的分子机制——一种计算建模方法	Argyris, G.	PDF	N/A	Molecular mechanisms of heart field specific cardiomyoscytedifferentiation- a computational modeling approach
在LRRK2突变但无路易体的情况下，存在丰富的非包含α-突触核蛋白病理。	Jensen, N. M.	PDF	N/A	Abundant non-inclusion α-synuclein pathology in Lewy body-negative LRRK2-mutant cases
α-突触核蛋白寡聚体在LRRK2相关帕金森病中的广泛分布	Sekiya, H.	PDF	N/A	Widespread Distribution of α-Synuclein Oligomers in LRRK2-related Parkinson's Disease
出生日期使前庭感觉神经元与传感器运动反射回路中的中枢和运动伙伴对齐，以实现注视稳定。	Huang, S.	PDF	N/A	Birthdate aligns vestibular sensory neurons with central and motor partners across a sensorimotor reflex circuit for gaze stabilization
产后感觉体验与桶状皮质改变预示着Cdkl5缺乏症小鼠模型中的自闭症特征	Raspanti, A.	PDF	N/A	Postnatal Sensory Experience and Barrel Cortex Alterations Anticipate Autistic Traits in a Mouse Model of Cdkl5 Deficiency Disorder
一种用于功能定向多部位和多尺度研究的混合微型ECoG	Jendritza, P.	PDF	N/A	A hybrid micro-ECoG for functionally targeted multi-site and multi-scale investigation
基于fMRI定义的非运动皮层目标的TMS诱发电位的重测信度	Sayali, C.	PDF	N/A	Test-retest reliability of TMS-evoked potentials over fMRI-based definitions of non-motor cortical targets
皮层连接性、局部动态和稳定性与全球意识状态的相关性	Zhao, Y.	PDF	N/A	Cortical connectivity, local dynamics and stability correlates of global conscious states
人类主体对虚拟环境中空间导航和知识获取的影响	Sanchez-Pacheco, T.	PDF	N/A	The impact of human agents on spatial navigation and knowledge acquisition in a Virtual Environment
在小鼠中，父母一方的犬尿氨酸3-单加氧酶基因型决定了子代性别特异性的行为结果。	Milosavljevic, S.	PDF	N/A	Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring
HIV-SEQ揭示了来自病毒血症和HIV抑制个体的HIV转录细胞之间的全球宿主基因表达差异	Frouard, J.	PDF	N/A	HIV-SEQ REVEALS GLOBAL HOST GENE EXPRESSION DIFFERENCES BETWEEN HIV-TRANSCRIBING CELLS FROM VIREMIC AND SUPPRESSED PEOPLE WITH HIV
野生咖啡（Baracoffea）物种中的建筑奇异性：综合形态学视角下的气候适应性咖啡栽培	Bezandry, R.	PDF	N/A	Architectural singularities in wild Coffea (Baracoffea) species: integrated morphological perspectives for climate-resilient coffee cultivation
埃及伊蚊和白纹伊蚊对塞浦路斯的入侵：当前状况、风险建模及对更广泛的东地中海地区公共卫生的影响。	Caminade, C.	PDF	N/A	The invasions of Aedes aegypti and Aedes albopictus in Cyprus: current situation, risk modelling and public health implications for the wider Eastern Mediterranean region.
啄还是不啄：早期社会环境对日本鹌鹑反应抑制和冲动攻击性的影响	Vernouillet, A.	PDF	N/A	To Peck or Not To Peck: The influence of early-life social environment on response inhibition and impulsive aggression in Japanese quails
在蝴蝶中，雌性嗅觉敏感性与雄性求偶行为在时间上是不同步的。	Murphy, M. J.	PDF	N/A	Female Olfactory Sensitivity is Temporally Asynchronous with Male Courtship in a Butterfly
AlphaFold对粘附家族G蛋白偶联受体（aGPCR）结构的预测与分析。	Zhou, X. W.	PDF	N/A	AlphaFold prediction and analysis of Adhesion-family G protein coupled receptor (aGPCR) structures.
Cluefish：通过聚合生物先验知识增强的超富集分析，挖掘转录数据系列的暗物质	Franklin, E.	PDF	N/A	Cluefish: mining the dark matter of transcriptional data series with over-representation analysis enhanced by aggregated biological prior knowledge
线粒体ACSS1在营养匮乏条件下调控淋巴瘤中的致癌代谢物2-羟基戊二酸和从头合成嘧啶	Basappa, J.	PDF	N/A	Mitochondrial ACSS1 regulates the oncometabolite 2-hydroxyglutarate and De Novo Pyrimidine biosynthesis under nutrient-deprived conditions in lymphoma
内皮剥离法在芯片上实现的内向性血管生成：跨管腔血管桥接的证据	Staples, S. C. R.	PDF	N/A	Intussusceptive angiogenesis-on-a-chip: Evidence for transluminal vascular bridging by endothelial delamination
接触新的雌性会提高成年雄性草原田鼠的繁殖力。	Hurd, J.	PDF	N/A	Exposure to novel females increases fecundity in adult male prairie voles
在诱导型启动子和普遍染色质开放元件（UCOE）之间的终止序列可以减少基因表达的泄漏和沉默。	Yanagi, T.	PDF	N/A	Termination sequence between an inducible promoter and ubiquitous chromatin opening element (UCOE) reduces gene expression leakage and silencing
刺激参数塑造有效连接路径：微状态分析对TMS诱发电位的洞察	Lucarelli, D.	PDF	N/A	Stimulation parameters shape effective connectivity pathways: insights from microstate analysis on TMS-evoked potentials
食物对昼夜节律时间调节的调控作用位于背侧迷走神经复合体	Chrobok, L.	PDF	N/A	Food-entrainment of circadian timekeeping in the dorsal vagal complex
成年小鼠的膳食铁缺乏会增加大脑内皮细胞对高亲和力抗转铁蛋白受体抗体的摄取和血脑屏障的运输。	Kostrikov, S.	PDF	N/A	Dietary iron deficiency in the adult mouse increases brain endothelial uptake and blood-brain barrier transport of a high-affinity, anti-transferrin receptor antibody
源到传感器的耦合（Source to sensor coupling, SoSeC）作为一种有效的工具，用于从EEG和MEG数据中定位相互作用的源。	Goeschl, F.	PDF	N/A	Source to sensor coupling (SoSeC) as an effective tool to localize interacting sources from EEG and MEG data
通过微流控流动池技术在人中性粒细胞中鉴定的羟基羧酸3受体的激活和信号传导特性	Forsman, H.	PDF	N/A	Activation and signaling characteristics of the hydroxy-carboxylic acid 3 receptor identified in human neutrophils through a microfluidic flow cell technique
根据韩国商业猪的血液学和免疫学参数建立特定年龄的区间	Song, D.	PDF	N/A	Establishment of age-specific intervals based on the hematological and immunological parameters of commercial pigs in the Republic of Korea
用于检测细菌中噬菌体抗性CBASS机制的LAMP-CRISPR-Cas13a技术	Ortiz-Cartagena, C.	PDF	N/A	The LAMP-CRISPR-Cas13a technique for detecting CBASS-mechanism of phage resistance in bacteria
硅-罗丹明辅助的识别（SeeID）技术用于近红外光控制的体外和体内邻近标记	Wang, W.	PDF	N/A	Silicon-rhodamine-enabled Identification (SeeID) for Near-Infrared Light Controlled Proximity Labeling In Vitro and In Vivo
一个位点控制区域在足月胎盘中生成不同的活性胎盘催乳素和非活性生长激素基因域，这些基因域在肥胖情况下会被破坏。	Jin, Y.	PDF	N/A	A Locus Control Region Generates Distinct Active Placental Lactogen And Inactive Growth Hormone Gene Domains In Term Placenta That Are Disrupted With Obesity
全基因组评估遗传拯救：一个奇特孤立且濒危蝴蝶的案例	MacDonald, Z. G.	PDF	N/A	Whole-genome evaluation of genetic rescue: the case of a curiously isolated and endangered butterfly
尽管有易感宿主的调控，蜗牛间的种内捕食现象仍推动了人类血吸虫的增殖。	Shaw, K. E.	PDF	N/A	Intraguild predation among snails drives human schistosome amplification despite susceptible host regulation
TFClassPredict：一种利用进化上保守的DNA结合域注释进行转录因子结合位点分析的新型深度学习框架	Timucin, C. H.	PDF	N/A	TFClassPredict: A Novel Deep Learning Framework for Transcription Factor Binding Site Analysis Using Evolutionarily Conserved DNA-Binding Domain Annotations
靶向横纹肌肉瘤中的从头胆固醇合成会导致细胞周期阻滞，并通过内质网应激介导的途径触发细胞凋亡。	Gizaw, N. Y.	PDF	N/A	Targeting de novo cholesterol synthesis in rhabdomyosarcoma induces cell cycle arrest and triggers apoptosis through ER stress-mediated pathways
发育中和成年人类大脑中肌营养不良蛋白异构体表达的综合时空图谱	Catapano, F.	PDF	N/A	A comprehensive spatiotemporal map of dystrophin isoform expression in the developing and adult human brain
用于分析基因-环境相互作用的通路多基因风险评分（pPRS）	Gauderman, W. J.	PDF	N/A	Pathway Polygenic Risk Scores (pPRS) for the Analysis of Gene-environment Interaction
工程化水凝胶生物材料促进从诱导多能干细胞分化为肺祖细胞	Tanneberger, A. E.	PDF	N/A	Engineered hydrogel biomaterials facilitate lung progenitor cell differentiation from induced pluripotent stem cells
细胞记忆：利用瓶颈式Transformer对分布外细胞进行分层解释	Wang, Q.	PDF	N/A	CellMemory: Hierarchical Interpretation of Out-of-Distribution Cells Using Bottlenecked Transformer
噬菌体T7激酶的普遍磷酸化作用使细菌防御失效。	Bartolec, T.	PDF	N/A	Pervasive phosphorylation by phage T7 kinase disarms bacterial defenses
利用SPDE方法推导的二维扩散估计尺度依赖协变量响应	Lindmark, M.	PDF	N/A	Estimating scale-dependent covariate responses using two-dimensional diffusion derived from the SPDE method
有强有力的证据表明，在硬骨鱼之间发生了多次免疫基因的水平转移。	Policarpo, M.	PDF	N/A	Strong evidence for multiple horizontal transfers of immune genes between teleost fishes
鉴定PTGR2抑制剂作为糖尿病和肥胖症的新疗法	Chang, Y.-C.	PDF	N/A	Identification of PTGR2 inhibitors as a new therapy for diabetes and obesity
脑脊液和血浆中apoE糖基化水平的增加与阿尔茨海默病生物标志物水平的降低有关。	Tharick, P.	PDF	N/A	Increased cerebrospinal fluid and plasma apoE glycosylation is associated with reduced levels of Alzheimer's disease biomarkers
# BioRxiv 2024-12-19 Papers

标题	作者	PDF链接	代码仓库	Title
翻山越岭，远赴他方：探究黑啄木鸟（Dryocopus martius，林奈，1758年）在活森林树木上挖掘树洞与景观因素的关联	Cabrera, C.	PDF	N/A	Over the hills and far away: linking landscape factors with cavity excavation on living forest trees by the Black woodpecker (Dryocopus martius, L. 1758)
通过AAV外源体测序的CRISPR筛选（CrAAVe-seq）是一种高度可扩展的、针对特定细胞类型的体内筛选平台。	Ramani, B.	PDF	N/A	CRISPR screening by AAV episome-sequencing (CrAAVe-seq) is a highly scalable cell type-specific in vivo screening platform
POLARIS是一种在拟南芥中参与乙烯信号调控所必需的铜结合肽。	Mudge, A. M.	PDF	N/A	POLARIS is a copper-binding peptide required for ethylene signalling control in Arabidopsis.
捕捉波浪：流行病学建模中行波解的适用性	Langmueller, A. M.	PDF	N/A	Catching a wave: on the suitability of traveling-wave solutions in epidemiological modeling
JAK2在介导细胞表面GHR-PRLR相互作用中的作用	Chen, C.	PDF	N/A	A role for JAK2 in mediating cell surface GHR-PRLR interaction
鼠与人：树突结构区分了人类与小鼠的神经网络	Kanari, L.	PDF	N/A	Of mice and men: Dendritic architecture differentiates human from mice neuronal networks
体内靶向和确定性的单细胞恶性转化	Scerbo, P.	PDF	N/A	In vivo targeted and deterministic single cell malignant transformation
使用COFE进行无需时间序列的节奏分析揭示了体内人类癌症的多组学昼夜节律	Ananthasubramaniam, B.	PDF	N/A	Time series-free rhythm profiling using COFE reveals multi-omic circadian rhythms in in vivo human cancers
通过计算机模拟设计具有高亲和力的稳定单域抗体	Van Der Kant, R.	PDF	N/A	In silico design of stable single-domain antibodies with high affinity
皮肤乳头细胞中的毒蕈碱型乙酰胆碱受体调节毛发生长。	Yuen, G. K.-W.	PDF	N/A	The muscarinic acetylcholine receptor in dermal papilla cells regulates hair growth
母性行为影响着大囊翼蝠的发声练习和学习过程。	Fernandez, A. A.	PDF	N/A	Maternal behavior influences vocal practice and learning processes in the greater sac-winged bat
溶解突触处的孔形成触发了经典的焦亡细胞死亡途径。	McKenzie, B.	PDF	N/A	Pore formation at the lytic synapse triggers the canonical pyroptotic cell death pathway
小鼠和非人灵长类动物发育中的大脑的功能成像	ZHU, J.	PDF	N/A	Functional Imaging of Developing Brain in Mice and Non-Human Primates
利用热力学和机器学习预测光合作用光捕获的多样性	Gray, C.	PDF	N/A	Predicting the diversity of photosynthetic light-harvesting using thermodynamics and machine learning
唤醒阈值揭示了与传统睡眠阶段无关的睡眠深度的新型神经标志物。	Picchioni, D.	PDF	N/A	Arousal threshold reveals novel neural markers of sleep depth independently from the conventional sleep stages
解码健康与精神分裂症中的脑结构-功能动态：两种模型的故事	Cai, Q.	PDF	N/A	Decoding Brain Structure-Function Dynamics in Health and in Psychosis: A Tale of Two Models
在斑马鱼脊髓损伤后，小胶质细胞向成纤维细胞和神经祖细胞发出信号，以调控再生性神经发生。	Docampo Seara, A.	PDF	N/A	Microglia signals to fibroblasts and neural progenitor cells to control regenerative neurogenesis after spinal cord injury in zebrafish
跨营养级群体的社会信息利用	Muniz, M.	PDF	N/A	Social information use across trophic guilds
白血病突变蛋白PHF6和PHIP形成一个染色质复合物，抑制急性髓性白血病的干细胞特性。	Pawar, A. S.	PDF	N/A	Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness
亚致死剂量的农药暴露会减少有益传粉者的交配行为，并扰乱其化学信号传递。	Derstine, N.	PDF	N/A	Sublethal pesticide exposure decreases mating and disrupts chemical signaling in a beneficial pollinator
认知努力与奖励。任务时间和多巴胺能及胆碱能基质参与的功能性成像研究	Orsini, C.	PDF	N/A	Cognitive effort and reward. Functional imaging of time on task and the involvement of dopaminergic and cholinergic substrates
鉴定髓样蛋白激酶C-ε为一种新型抗动脉粥样硬化基因	Wells, A. T.	PDF	N/A	Identification of Myeloid Protein Kinase C - Epsilon as a Novel Atheroprotective Gene
半胱氨酸反应性共价RNF4配体CCW16通过激活ROS信号传导诱导AML细胞发生铁死亡。	Gotthardt, G.	PDF	N/A	The cysteine-reactive covalent RNF4 ligand CCW16 induces ferroptosis in AML cells by activation of ROS signaling
水稻中α-伸展蛋白前体的结构表征与功能评估	Nayem, R. I.	PDF	N/A	Structural Characterization and Functional Assessment of the Alpha-Expansin Precursor in Oryza sativa
秀丽隐杆线虫中唯一必需的低分子量原肌球蛋白异构体对其咽肌功能至关重要。	Kimmich, M. J.	PDF	N/A	The sole essential low molecular weight tropomyosin isoform of Caenorhabditis elegans is essential for pharyngeal muscle function.
大脑图谱显示了普遍认知功能及其与神经生物学皮质特征的空间相关性	Moodie, J. E.	PDF	N/A	Brain maps of general cognitive function and spatial correlations with neurobiological cortical profiles
一种新型泛I类葡萄糖转运蛋白抑制剂DRB18在体外和体内与紫杉醇联合使用对人类非小细胞肺癌表现出协同效应。	Shriwas, P.	PDF	N/A	A novel pan class-I glucose transporter inhibitor DRB18 exhibits synergistic effects in vitro and in vivo with paclitaxel against human non-small cell lung cancer
一个包含二倍体端粒到端粒参考的阿联酋泛基因组	Olbrich, M. R.	PDF	N/A	An Emirati pangenome incorporating a diploid telomere-to-telomere reference
特定损伤肌肉再生：细胞和细胞因子驱动的计算蓝图	Haase, M.	PDF	N/A	Injury-Specific Muscle Regeneration: A Computational Blueprint for Cellular and Cytokine Drivers
神经炎症大鼠模型中胶质相关血管运动诱导血流动态行波：对功能性神经影像学的启示	Pereira, M.	PDF	N/A	Induction of hemodynamic traveling waves by glial-related vasomotion in a rat model of neuroinflammation: implications for functional neuroimaging
线索和情境的独特表征特性塑造了恐惧学习和消退的过程。	Bouyeure, A.	PDF	N/A	Distinct representational properties of cues and contexts shape fear learning and extinction
着丝粒和近着丝粒染色质稳定性的独立性与CCAN组分无关	Biggs, R. J.	PDF	N/A	Independence of centromeric and pericentromeric chromatin stability on CCAN components
帮助我将这段翻译成中文，探索轴向模式化并将体外模型投影到体内空间的鼠胚胎原肠运动和早期器官发生时空图谱	Harland, L. T.	PDF	N/A	A Spatiotemporal Atlas of Mouse Gastrulation and Early Organogenesis to Explore Axial Patterning and Project In Vitro Models onto In Vivo Space
源头到河谷：河流从森林过渡到农业低地的水质变化	Neufeld, D.	PDF	N/A	Headwaters to Valley: Water quality in rivers transitioning from forest to agricultural bottomland
在连接的作物景观中优化杀菌剂的部署，同时平衡流行病控制和环境可持续性	Radici, A.	PDF	N/A	Optimizing fungicide deployment in a connected crop landscape while balancing epidemic control and environmental sustainability
小麦白粉菌（Zymoseptoria tritici）对温度冲击的反应揭示了特定的转录重编程及热适应的新候选基因	Minana-Posada, S.	PDF	N/A	Responses to temperature shocks in Zymoseptoria tritici reveal specific transcriptional reprogramming and novel candidate genes for thermal adaptation
DNMT1的缺失导致DNMT3A介导的部分晚期复制域的过度甲基化。	Kafetzopoulos, I.	PDF	N/A	DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A
原始神经系统中的神经肽介导的时间感觉过滤	Wyss, L. S.	PDF	N/A	Neuropeptide-mediated temporal sensory filtering in a primordial nervous system
通过适应性实验室进化在常温下实现高效的微生物葡萄糖-果糖转化，并应用于D-阿洛酮糖的生产。	Lehnert, A.	PDF	N/A	Efficient microbial glucose-fructose conversion at ambient temperature through adaptive laboratory evolution and application for D-allulose production
基准测试抗体CDR序列设计的逆折叠模型	Greisen, P. J.	PDF	N/A	Benchmarking Inverse Folding Models for Antibody CDR Sequence Design
AlphaFold 3蛋白质组模型揭示了淡水蓝藻病毒中存在多个光系统结构同源物	Meza-Padilla, I.	PDF	N/A	AlphaFold 3 proteomic modelling reveals multiple photosystem structural homologs in freshwater cyanophages
利用大型语言模型对基因集进行深度功能分析：定制化、情境感知功能注释的蓝图	khan, t.	PDF	N/A	Deep functional profiling of gene sets using Large Language Models: A blueprint for tailored, context-aware functional annotation
ParaSurf：一种基于表面的深度学习方法用于预测抗原决定簇与抗原相互作用	Papadopoulos, A. M.	PDF	N/A	ParaSurf: A Surface-Based Deep Learning Approach for Paratope-Antigen Interaction Prediction
交叉验证坐标元分析：对比分析	Tench, C. R.	PDF	N/A	Cross validation coordinate meta-analysis: contrast analysis
CD24-Fc 能够缓解炎症，并在接受抗逆转录病毒治疗（cART）的 HIV-1 感染期间，拯救具有多功能性的 CD8 T 细胞。	Su, L.	PDF	N/A	CD24-Fc resolves inflammation and rescues CD8 T cells with polyfunctionality during HIV-1 infection under cART
缺陷型DcpS脱帽表现为肌酸缺乏综合征和神经功能障碍	Yang, J.	PDF	N/A	Defective DcpS Decapping Manifests in Creatine Deficiency Syndrome and Neurological impairment
单一超级克隆的传播推动了杀虫剂抗性在入侵范围内的Acyrthosiphon kondoi中的扩散。	Thia, J. A.	PDF	N/A	Spread of a single superclone drives insecticide resistance in Acyrthosiphon kondoi across an invasive range
B型细胞周期蛋白Clb4阻止了出芽酵母中减数分裂I姐妹着丝粒的分离。	Lumbroso, G.	PDF	N/A	The B-type cyclin Clb4 prevents meiosis I sister centromere separation in budding yeast
# BioRxiv 2024-12-18 Papers

标题	作者	PDF链接	代码仓库	Title
sortase组装的Ebp菌毛在粪肠球菌粘附于氧化铁及其对胞外电子传递影响中的作用	Ho, F. K.	PDF	N/A	Role of sortase-assembled Ebp pili in Enterococcus faecalis adhesion to iron oxides and its impact on extracellular electron transfer
突变和选择对秀丽隐杆线虫对细菌病原体易感性的累积效应	Saber, S.	PDF	N/A	Cumulative effects of mutation and selection on susceptibility to bacterial pathogens in Caenorhabditis elegans
光感受器与视网膜色素上皮之间的葡萄糖和乳酸的体内交换	Hass, D. T.	PDF	N/A	In vivo exchange of glucose and lactate between photoreceptors and the retinal pigment epithelium
环境DNA在评估再生农业下蚯蚓生物多样性恢复方面比手工分类更为有效。	Llanos, J.	PDF	N/A	Environmental DNA is more effective than hand sorting in evaluating earthworm biodiversity recovery under regenerative agriculture
扩展深度可识别模型能够实现单细胞生物状态的零样本表征	Dong, M.	PDF	N/A	Scaling deep identifiable models enables zero-shot characterization of single-cell biological states
选择预期作为感官预测的门控累积	Caie, B.	PDF	N/A	Choice anticipation as gated accumulation of sensory predictions
通过寄生而非捕食频繁传播的沃尔巴克氏菌的种间传播	Yan, Z.-C.	PDF	N/A	Frequent intertrophic transmission of Wolbachia by parasitism but not predation
简单的壳体测量并不能始终准确预测龟类的栖息地：对Lichtig和Lucas（2017）的回应	Evers, S. W.	PDF	N/A	Simple shell measurements do not consistently predict habitat in turtles: a reply to Lichtig and Lucas (2017)
一种应激依赖的TDP-43 SUMO化程序维持神经元功能	Suk, T. R.	PDF	N/A	A stress-dependent TDP-43 SUMOylation program preserves neuronal function
循环肿瘤细胞在毛细血管大小的分叉处释放大量细胞外囊泡。	Vrynas, A.	PDF	N/A	Circulating tumor cells shed large extracellular vesicles in capillary-sized bifurcations
皮层对层次化节奏的追踪，协调了生物运动的多感官处理过程。	Shen, L.	PDF	N/A	Cortical tracking of hierarchical rhythms orchestrates the multisensory processing of biological motion
MDF调控了拟南芥中依赖和不依赖生长素的侧根再生途径网络。	Aldowigh, F.	PDF	N/A	MDF regulates a network of auxin-dependent and -independent pathways of adventitious root regeneration in Arabidopsis.
一种宿主酶通过灭活肠道脂多糖来减轻代谢功能障碍相关脂肪性肝病（MASLD）	Wang, Z.	PDF	N/A	A Host Enzyme Reduces Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) by Inactivating Intestinal Lipopolysaccharide
从无人机记录的蝴蝶运动描绘了其在野外的迁徙飞行行为。	de Margerie, E.	PDF	N/A	Butterfly movements recorded from a UAV depict migratory flight behaviour in the wild.
一种新方法（RIM-Deep）增强了倒置共聚焦显微镜下深层清除脑组织成像的深度和分辨率稳定性。	Liu, Y.	PDF	N/A	A novel method (RIM-Deep) enhances imaging depth and resolution stability of deep-cleared brain tissue in inverted confocal microscopy
监控与群体网络协同作用在理解2018年法国大都会区乌苏病毒在普通乌鸫（Turdus merula）中的爆发中的相关性	Bouchez-Zacria, M.	PDF	N/A	Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018
PA28γ通过提高线粒体功能促进肿瘤的恶性进展，这一过程依赖于C1QBP。	Wang, J.	PDF	N/A	PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
细胞类型间代谢身份的表观遗传调控	Pacheco, M. P.	PDF	N/A	Epigenetic control of metabolic identity across cell types
突出发病机制的复杂性：宿主微生物群影响苹果果实疾病的发展，是其生物防治的基石。	Sare, A. R.	PDF	N/A	Highlighting the complexity of pathogenesis: the host microbiota impacts disease development on apple fruit and is a cornerstone for its biocontrol
利用angioMASH组织清除和标记技术，在三维空间中研究人类视觉皮层的微观血管结构。	Hildebrand, S.	PDF	N/A	Investigating microscopic angioarchitecture in the human visual cortex in 3D with angioMASH tissue clearing and labelling
澳大利亚犬钩虫（Ancylostoma caninum）中普遍存在苯并咪唑抗性单核苷酸多态性	Abdullah, S.	PDF	N/A	Widespread occurrence of benzimidazole resistance single nucleotide polymorphisms in the canine hookworm, Ancylostoma caninum, in Australia
ERK2二聚体在突触可塑性和记忆中的作用	Ojea Ramos, S.	PDF	N/A	Role of ERK2 dimerization in synaptic plasticity and memory
神经元培养基中星形胶质细胞Nrf2的基础激活：神经元-星形胶质细胞模型构建的挑战与意义	Elsharkasi, M. M. O.	PDF	N/A	Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling
鉴定新型毒素结构域并表征广泛分布的脂质靶向NlpC/P60家族。	Nicastro, G. G.	PDF	N/A	Identification of novel toxin domains and characterization of a broadly distributed family of lipid-targeting NlpC/P60.
使用12-6 Lennard-Jones势能模型模拟银(I)离子与蛋白质的相互作用：一种自下而上的参数化方法	Manciocchi, L.	PDF	N/A	Modelling the interaction between silver(I) ion and proteins with the 12-6 Lennard-Jones potential: a bottom-up parameterization approach
鸟类端脑和小脑的体积可以通过数字脑内模精确估算。	Keirnan, A. R.	PDF	N/A	Avian telencephalon and cerebellum volumes can be accurately estimated from digital brain endocasts
蛋白质进化中的波动与可预测性极限	Rossi, S.	PDF	N/A	Fluctuations and the limit of predictability in protein evolution
PARP抑制剂可逆转替莫唑胺在多形性胶质母细胞瘤中的耐药性。	Samarut, E.	PDF	N/A	PARP inhibitor counteracts Temozolomide Resistance in Glioblastoma Multiforme
利用组织病理学图像进行个性化医疗的深度学习驱动结直肠癌亚型分类	Trong Le Phan, N.	PDF	N/A	Deep Learning-Driven Subtype Classification of Colorectal Cancer Using Histopathology Images for Personalized Medicine
自然语言理解在理解后的一秒内会激活一系列广泛的大脑网络。	Hong, M. K.	PDF	N/A	Naturalistic language comprehension engages a cascade of widespread brain networks in the one second following comprehension
通过对数百个不同大脑进行长读段测序，我们得以深入了解结构变异对基因表达和DNA甲基化的影响。	Billingsley, K. J.	PDF	N/A	Long-read sequencing of hundreds of diverse brains provides insight into the impact of structural variation on gene expression and DNA methylation
卡西尼：用于RNA和蛋白质原位分析的流线型可扩展方法	Lapique, N.	PDF	N/A	Cassini: Streamlined and Scalable Method for in situ profiling of RNA and Protein
非洲疟疾媒介按蚊的基因组多样性	Bodde, M.	PDF	N/A	Genomic diversity of the African malaria vector Anopheles funestus
发育中的人脑的三维组织学细胞图谱	Jayakumar, J.	PDF	N/A	A three-dimensional histological cell atlas of the developing human brain
整合宏基因组组装的基因组与临床分离株揭示了克雷伯氏肺炎菌在携带和疾病中的基因组特征	Gupta, S.	PDF	N/A	Integration of metagenome-assembled genomes with clinical isolates reveals genomic signatures of Klebsiella pneumoniae in carriage and disease
盐诱导的蜡样芽孢杆菌MHS的超蠕动运动减少与鞭毛减少、纳米管形成减少以及群体感应调节因子表达减少有关。	Bhadani, N. K.	PDF	N/A	Salt-induced reduction of hyperswarming motility in Bacillus cereus MHS is associated with reduced flagellation, reduced nanotube formation and reduction in expression of quorum sensing regulator
评估多粘菌素B与三氯生联合治疗对耐粘菌素肺炎克雷伯菌的疗效	Biswas, S.	PDF	N/A	Assessing the efficacy of therapeutically promising combination of polymyxin B and triclosan against colistin resistant Klebsiella pneumoniae
己糖胺生物合成中断会损害GPI生产并使恶性疟原虫在裂殖体阶段停止生长	Alberione, M. P.	PDF	N/A	Hexosamine Biosynthesis Disruption Impairs GPI Production and Arrests Plasmodium falciparum Growth at Schizont Stages
异氟芬喹，新型二氢乳清酸脱氢酶抑制剂：对草莓病害的疗效及通过AlphaFold2和Autodock Vina进行的对接模拟	Choi, S.	PDF	N/A	Ipflufenoquin, Novel Dihydroorotate Dehydrogenase Inhibitor: Efficacy Against Strawberry Diseases and Docking Simulations via AlphaFold2 and Autodock Vina
与RNA聚合酶II和RNA相互作用的保守蛋白Seb1是一种真正的转录延伸因子。	Kus, K.	PDF	N/A	Conserved protein Seb1 that interacts with RNA polymerase II and RNA is a bona fide transcription elongation factor
通过隐秘口袋映射与X射线片段筛选相结合，增强了对与hnRNPA1结合的小分子的识别。	Dunnett, L.	PDF	N/A	Enhanced identification of small molecules binding to hnRNPA1 via cryptic pockets mapping coupled with X-Ray fragment screening
在工程菌中结合生物合成与位点特异性引入苯丙氨酸衍生物：从芳香醛或羧酸合成	Anderson, S.	PDF	N/A	Combined biosynthesis and site-specific incorporation of phenylalanine derivatives from aryl aldehydes or carboxylic acids in engineered bacteria
一种在大肠杆菌中生产生物活性肽的蛋白质笼系统	Harding, M. D.	PDF	N/A	A protein cage system for producing bioactive peptides in Escherichia coli
网格蛋白参与了疟原虫对宿主细胞质内吞作用的过程。	Miao, J.	PDF	N/A	Clathrins are involved in the endocytosis of host cytosol in the malaria parasite
将解构的酸面团群落和发酵参数应用于低FODMAP小麦面包的生产。	Wittwer, A. E.	PDF	N/A	Applying deconstructed sourdough communities and fermentation parameters to low-FODMAP wheat bread production
氧化应激激发吡嗪酰胺对结核分枝杆菌的强效杀菌活性	Dillon, N.	PDF	N/A	Oxidative stress drives potent bactericidal activity of pyrazinamide against Mycobacterium tuberculosis
金黄色葡萄球菌滑行彗星：形成与观察	Pollitt, E.	PDF	N/A	Staphylococcus aureus gliding comets: formation and observation
一项针对沙门氏菌肠亚种鼠伤寒沙门氏菌的全基因组CRISPRi筛选揭示了I型菌毛在逃避抗体介导的凝集中的作用。	Lindberg, S. K.	PDF	N/A	A Salmonella enterica serovar Typhimurium Genome-wide CRISPRi Screen Reveals a Role for Type 1 Fimbriae in Evasion of Antibody-Mediated Agglutination
微生物对海藻酸盐的觅食行为在地理和分类学上不同的反刍动物微生物群中是保守的。	Ferrillo, A.	PDF	N/A	Microbial alginate foraging is conserved in geographically and taxonomically distinct ruminant microbiomes
在变异链球菌菌株中检测防御系统和前噬菌体	Claisse, O.	PDF	N/A	Defense systems and prophage detection in Streptococcus mutans strains
红细胞质膜钙ATP酶（PMCA4b）的变异通过介导氧化还原失衡来决定疟疾对青蒿素的敏感性。	Agrohi, P.	PDF	N/A	Erythrocytic plasma membrane calcium ATPase (PMCA4b) variations mediate redox imbalance to determine artemisinin sensitivity in malaria
通过重构外膜蛋白BamA来杀死革兰氏阴性菌的抗生素	Modaresi, S. M.	PDF	N/A	Antibiotics that Kill Gram-negative Bacteria by Restructuring the Outer Membrane Protein BamA
Mbd4和MutSα保护细胞免受5-甲基胞嘧啶自发脱氨基的影响。	Bilardi, R. A.	PDF	N/A	Mbd4 and MutSα protect cells from spontaneous deamination of 5-methylcytosine.
DUX4诱导的HSATII RNA积累驱动蛋白质聚集，影响RNA加工途径。	Arends, T.	PDF	N/A	DUX4-induced HSATII RNA accumulation drives protein aggregation impacting RNA processing pathways.
将CRISPR扫描与靶向染色质可及性分析相结合，使用双链DNA脱氨酶	Roh, H.	PDF	N/A	Coupling CRISPR Scanning with Targeted Chromatin Accessibility Profiling using a Double-Stranded DNA Deaminase
随机生长爆发使单个细菌能够无负担地生产鞭毛	Garcia-Alcala, M.	PDF	N/A	Stochastic Growth Bursts Enable Burden-Free Flagellum Production in a Single Bacterium
果蝇Bam和Bgcn序列的比较分析及预测的蛋白质结构进化	Arnce, L.	PDF	N/A	Comparative Analysis of Drosophila Bam and Bgcn Sequences and Predicted Protein Structural Evolution
转座元件驱动F-box基因的调控和功能创新	Almeida, M. V.	PDF	N/A	Transposable elements drive regulatory and functional innovation of F-box genes
哺乳动物中转座元件的剂量补偿	Wei, C.	PDF	N/A	Dosage compensation of transposable elements in mammals
D型细胞周期蛋白被AMBRA1 E3连接酶受体识别的机制	Wang, Y.	PDF	N/A	Mechanism of D-type cyclins recognition by the AMBRA1 E3 ligase receptor
从基因组语言模型中对功能性新生基因进行语义挖掘	Merchant, A. T.	PDF	N/A	Semantic mining of functional de novo genes from a genomic language model
一个可热插拔的遗传开关：构建一个对必需基因MEDIATOR 21的可诱导且可追踪的功能性检测	Watson, I. J.	PDF	N/A	A Hot-Swappable Genetic Switch: Building an inducible and trackable functional assay for the essential gene MEDIATOR 21
对代谢组学数据的重新分析揭示，微生物群移植疗法能够调节自闭症谱系障碍儿童的粪便和血浆代谢物特征。	Nirmalkar, K.	PDF	N/A	Reanalysis of metabolomics data reveals that microbiota transfer therapy modulates important fecal and plasma metabolite profiles in children with autism spectrum disorders
丙酮酸激酶在糖酵解过程中直接生成GTP，支持细胞生长并参与鸟苷毒性作用。	She, F.	PDF	N/A	Pyruvate Kinase Directly Generates GTP in Glycolysis, Supporting Growth and Contributing to Guanosine Toxicity
社会任务和攻击性塑造了高度社会性蜜蜂头部中的免疫基因表达水平。	Campana, L.	PDF	N/A	Social task and aggressiveness shape immunity gene expression levels in the head of highly eusocial bees
非洲霍乱弧菌分离株的基因组多样性和抗菌药物耐药性：一项利用纳米孔测序技术加强基因组监测的PulseNet Africa计划	Foster-Nyarko, E.	PDF	N/A	Genomic Diversity and Antimicrobial Resistance of Vibrio cholerae Isolates from Africa: A PulseNet Africa Initiative Using Nanopore Sequencing to Enhance Genomic Surveillance
利用DNA纳米结构对生化反应进行空间条码编码揭示了邻近标记中的主要接触机制。	Yang, Z.	PDF	N/A	Spatially barcoding biochemical reactions using DNA nanostructures unveil a major contact mechanism in proximity labeling
在结直肠癌中模拟奥沙利铂耐药性揭示了基于SERPINE1的基因特征（RESIST-M）及针对促转移CMS4亚型的治疗策略	Wong, S. Q. R.	PDF	N/A	Modelling oxaliplatin resistance in colorectal cancer reveals a SERPINE1-based gene signature (RESIST-M) and therapeutic strategies for pro-metastatic CMS4 subtype
MADS-box基因家族在微调塔罗霉素马尔内菲（Talaromyces marneffei）双态转变中的功能多样化	Hu, X.	PDF	N/A	Functional diversification of the MADS-box gene family in fine-tuning the dimorphic transition of Talaromyces marneffei
冠心病与糖尿病之间的差异代谢生物标志物	Wang, Z.	PDF	N/A	Differential metabolic biomarkers between coronary heart disease and diabetes mellitus
主要组织相容性复合体：真菌疾病易感性中的双刃剑	FU, M.	PDF	N/A	The major histocompatibility complex: a double-edged sword in fungal disease susceptibility
直接表达CPT1a能够实现一个高通量的平台，用于发现CPT1a的调节剂。	Chen, J.	PDF	N/A	Direct expression of CPT1a enables a high throughput platform for the discovery of CPT1a modulators
生成专家指导的、简化的本体论视图的一般策略	Caron, A. R.	PDF	N/A	A general strategy for generating expert-guided, simplified views of ontologies
CoPPIs算法：揭示病理生理条件下蛋白质协同策略的工具	Lomagno, A.	PDF	N/A	CoPPIs Algorithm: A Tool to Unravel Protein Cooperative Strategies in Pathophysiological Conditions
突触易化增强了高频神经传递的可靠性和精确性。	Bernal-Correa, A. M.	PDF	N/A	Synaptic facilitation enhances the reliability and precision of high frequency neurotransmission
当存在背叛者时，互惠合作可以稳定，因为这促使了歧视行为的出现。	Roberts, G.	PDF	N/A	Reciprocal cooperation can be stable when the presence of defectors selects for discrimination
杜氏肌营养不良症中早期内体紊乱与内溶酶体途径功能障碍	Chassagne, J.	PDF	N/A	Early endosome disturbance and endolysosomal pathway dysfunction in Duchenne muscular dystrophy
通过肌节分裂实现肌肉增长	Rodier, C.	PDF	N/A	Muscle growth by sarcomere divisions
在成年斑马鱼心脏再生过程中，受损的心内膜获得了造血内皮细胞的特性。	Ying, J.	PDF	N/A	Injured endocardium obtains characteristics of haemogenic endothelium during adult zebrafish heart regeneration
褪黑素调控Nrf2/HO-1通路对甲醛暴露所致急性肺损伤的潜在机制及效应	Wang, B.	PDF	N/A	Potential mechanisms and effects of melatonin-regulated Nrf2/HO-1 pathway on acute lung injury due to formaldehyde exposure
一个用于评估单只果蝇学习和记忆的高通量平台：个体果蝇嗅觉条件化器（iDOC）	Ortega, A.	PDF	N/A	A High-Throughput Platform for Assessing Single Fly Learning and Memory: Individual Drosophila Olfactory Conditioner (iDOC)
运动与即时听觉反馈相结合如何影响大鼠的自发行为？	Yoshida, K.	PDF	N/A	How does immediate auditory feedback coupled to locomotion influence the spontaneous actions of rats?
细胞外囊泡RNA具有糖基化修饰	Sharma, S.	PDF	N/A	Extracellular Exosomal RNAs are Glyco-Modified
多泛素化的跨膜蛋白在网格蛋白包被的小泡内部有限的容纳空间中，能够胜过其他货物蛋白。	Liu, H.-Y.	PDF	N/A	Poly-ubiquitylated transmembrane proteins outcompete other cargo for limited space inside clathrin-coated vesicles
一项CRISPR/Cas9筛选揭示了位于内体-高尔基体界面并调控细胞ASO活性的蛋白质	Malong, L.	PDF	N/A	A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular ASO activity
过度活跃的PLCG1驱动非经典信号传导以促进细胞存活	Zeng, L.	PDF	N/A	Hyperactive PLCG1 drives non-canonical signaling to promote cell survival
年龄和性别在人类初级肌细胞中的转录组特征并不保守。	Lamon, S.	PDF	N/A	The transcriptomic signature of age and sex is not conserved in human primary myocytes
M2巨噬细胞表达的TGF-β通过抑制间充质干细胞的TSG-6表达来促进伤口愈合。	Eom, Y. W.	PDF	N/A	TGF-β expressed by M2 macrophages promotes wound healing by inhibiting TSG-6 expression by mesenchymal stem cells
ABHD2活性对于孕酮在人类精子上的非基因组作用并非必需。	Arnolds, O.	PDF	N/A	ABHD2 activity is not required for the non-genomic action of progesterone on human sperm
N-末端Halo-tag对小鼠GIPR功能生理影响的探讨	Davies, I.	PDF	N/A	The physiological impact of an N-terminal Halo-tag on GIPR function in mice
病毒诱导的囊泡酸化增强HIV免疫逃逸。	Yaple-Maresh, M. E.	PDF	N/A	Virus-induced vesicular acidification enhances HIV immune evasion.
年轻男性在八小时极端高温暴露期间的液体补充与急性全身炎症反应综合征	Wang, F.	PDF	N/A	Fluid replacement and acute systemic inflammatory response syndrome during eight-hour extreme heat exposure in young men
斑马鱼罗盘神经元中塑料地标锚定的机制	Tanaka, R.	PDF	N/A	Mechanisms for plastic landmark anchoring in zebrafish compass neurons
UTX通过表观遗传方式在自身反应性干细胞样CD8+ T细胞前体中强制执行一种细胞溶解效应程序。	Chen, H.-C.	PDF	N/A	UTX Epigenetically Imposes a Cytolytic Effector Program in Autoreactive Stem-like CD8+ T cell Progenitors
母体血液中独特的DNA甲基化特征揭示了子痫前期及产后期过渡期间独特的免疫细胞变化	Jamshed, L.	PDF	N/A	Distinct DNA Methylation Signatures in Maternal Blood Reveal Unique Immune Cell Shifts in Preeclampsia and the Pregnancy-Postpartum Transition
加拿大太平洋驼背鲸中合作与单独气泡网捕食的传播	Wray, J.	PDF	N/A	The diffusion of cooperative and solo bubble net feeding in Canadian Pacific humpback whales
可持续纤维素生物纳米复合材料的域结构与机械刚度界面控制	Jin, H.	PDF	N/A	Domain Structure and Interface Control of Mechanical Stiffness in Sustainable Cellulose Bio-nanocomposites
# BioRxiv 2024-12-17 Papers

标题	作者	PDF链接	代码仓库	Title
杆状细菌荧光假单胞菌SBW25的球形mreB缺失突变体的进化救援	Yulo, P. R.	PDF	N/A	Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
机械压缩力增加了乳腺癌和胰腺癌细胞中的PI3K输出信号。	Di-Luoffo, M.	PDF	N/A	Mechanical compressive forces increase PI3K output signaling in breast and pancreatic cancer cells
一种依赖于Hfq的转录后机制微调了大肠杆菌中RecB的表达	Kalita, I.	PDF	N/A	An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli
重新审视替代负荷：高比例的死亡可能是选择性的	Matheson, J. D.	PDF	N/A	Substitution load revisited: a high proportion of deaths can be selective
六亚甲基二醇对FUS相分离影响的分子洞察	Zheng, T.	PDF	N/A	Molecular insights into the effect of hexanediol on FUS phase separation
突触对胆碱能投射神经元的失调导致在5种果蝇帕金森模型中出现嗅觉功能障碍。	Pech, U.	PDF	N/A	Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models
眼跳前中央凹预测的幅度和时间进程取决于眼跳目标的显著性。	Kroell, L. M.	PDF	N/A	The magnitude and time course of pre-saccadic foveal prediction depend on the conspicuity of the saccade target
一个新的通用树形指数系统	Noble, R. J.	PDF	N/A	A new universal system of tree shape indices
成年果蝇大脑和身体中的空间转录组学	Janssens, J.	PDF	N/A	Spatial transcriptomics in the adult Drosophila brain and body
感知与注意力对意识访问的损害：尽管任务表现相同，但神经机制不同	Noorman, S.	PDF	N/A	Perceptual versus attentional impairments of conscious access: Distinct neural mechanisms despite equal task performance
一种用于快速DNA片段计数和基因分型的模糊序列发生器	Zhou, W.	PDF	N/A	A fuzzy sequencer for rapid DNA fragment counting and genotyping
人类第二视觉区域中颜色、视差和自然纹理的中尺度功能组织与连接性	Ai, H.	PDF	N/A	Mesoscale functional organization and connectivity of color, disparity, and naturalistic texture in human second visual area
一个用于自动和广义突触事件分析的深度学习框架	O'Neill, P. S.	PDF	N/A	A deep learning framework for automated and generalized synaptic event analysis
基于记忆的偏好的主动和被动构建	Nicholas, J.	PDF	N/A	Proactive and reactive construction of memory-based preferences
大规模骨骼肌单核多组学分析揭示了广泛的上下文特异性遗传调控	Varshney, A.	PDF	N/A	Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation
prestin对氯离子的结合并不会影响小鼠外毛细胞中极高频率的复杂非线性电容（cNLC）。	Bai, J.-P.	PDF	N/A	Chloride binding to prestin does not influence very high-frequency complex nonlinear capacitance (cNLC) in the mouse outer hair cell
揭示先天性耳聋对个体大脑组织的影响	Amaral, L.	PDF	N/A	Unraveling the impact of congenital deafness on individual brain organization
孕期神经生物学变化的纵向研究	Niu, Y.	PDF	N/A	Longitudinal Investigation of Neurobiological Changes Across Pregnancy
用于从文献中提取生物学证据的Lit-OTAR框架	Tirunagari, S.	PDF	N/A	Lit-OTAR Framework for Extracting Biological Evidences from Literature
附睾在受精之外的贡献：CRISP1和CRISP3对精子DNA完整性和早期胚胎发育的相关性	Sulzyk, V.	PDF	N/A	Contribution of the epididymis beyond fertilization: relevance of CRISP1 and CRISP3 for sperm DNA integrity and early embryo development
解读延长寿命干预的时间与影响：时间效能分析器区分早期、中年和衰老阶段的效能	Jiang, N.	PDF	N/A	Deciphering the Timing and Impact of Life-extending Interventions: Temporal Efficacy Profiler Distinguishes Early, Midlife, and Senescence Phase Efficacies
一个多功能的个人信息检索框架，用于评估个人资料的强度和相似度。	Kalinin, A. A.	PDF	N/A	A versatile information retrieval framework for evaluating profile strength and similarity
拟南芥FCA凝聚体在RNA 3'端加工中的体内特性	Jang, G.-J.	PDF	N/A	In vivo properties of Arabidopsis FCA condensates involved in RNA 3' processing
凝聚蛋白IDC、H4K20me1及核周锚定共同维持秀丽隐杆线虫X染色体的抑制状态。	Trombley, J.	PDF	N/A	Condensin IDC, H4K20me1, and perinuclear tethering maintain X chromosome repression in C. elegans
第六层皮层间神经元是大脑半球内和大脑半球间反馈的主要途径。	Weiler, S.	PDF	N/A	Layer 6 corticocortical neurons are a major route for intra and interhemispheric feedback
饮食预测了大西洋鲑鱼在整个生命周期中的表现权衡	Aykanat, T.	PDF	N/A	Diet predicts performance trade-offs along Atlantic salmon ontology
跨组织性别偏倚基因表达揭示了三刺鱼鳃中意想不到的差异。	Sylvestre, F.	PDF	N/A	Sex-biased gene expression across tissues reveals unexpected differentiation in the gills of the threespine stickleback
放线菌素D和硼替佐米破坏维尔姆斯肿瘤中的蛋白质稳态	Tiburcio, P. D. B.	PDF	N/A	Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
多发性硬化进展中的性别差异单细胞图谱	Soler-Saez, I.	PDF	N/A	Single cell landscape of sex differences in the progression of multiple sclerosis
一种开花时间可塑性的反应规范揭示了玉米适应性的生理痕迹	Drouault, J.	PDF	N/A	A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation
加利福尼亚沿海湿地中沿陆地-海洋断面的隐匿甲烷循环和甲基营养代谢的空间证据	Krause, S. J. E.	PDF	N/A	Spatial evidence of cryptic methane cycling and methylotrophic metabolisms along a land-ocean transect in a California coastal wetland
在干旱胁迫下，高粱根部在营养生长期内的转录变化和微生物群动态	Kabir, A. H.	PDF	N/A	Transcriptional shifts and microbiome dynamics in sorghum roots during vegetative growth under drought stress
Amidase和Lysozyme在TseP中的双重功能揭示了Type VI分泌系统中一个新的嵌合效应因子家族	Wang, Z.-H.	PDF	N/A	Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System
普通狨猴利用身体姿势作为一种多功能信号，用于发起、维持和调整社交游戏。	Adriaense, J. E. C.	PDF	N/A	Common marmosets use body posture as multi-functional signal to solicit, maintain, and modify social play
致癌代谢物D-2-羟基戊二酸在IDH突变型胶质瘤中促进控制小胶质细胞激活的谱系特异性增强子的DNA高甲基化。	Laurenge, A.	PDF	N/A	The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas
GPRC6A作为一种新型鲜味受体，通过鸟氨酸增强味觉偏好。	Yamamoto, T.	PDF	N/A	GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine
为功能性神经成像创建基于解剖学、标准化、可定制且可三维打印的头帽	McCann, A.	PDF	N/A	Creating anatomically-derived, standardized, customizable, and three-dimensional printable head caps for functional neuroimaging
脂质囊泡中膜弯曲与拉伸的耦合关系	Wennerström, H.	PDF	N/A	On the coupling between membrane bending and stretching in lipid vesicles
灵活且强大的细胞类型注释，适用于高度多重化的组织图像	Sun, H.	PDF	N/A	Flexible and robust cell type annotation for highly multiplexed tissue images
LM-Merg并：一种用于合并逻辑模型的流程，应用于基因调控	Li, L. X.	PDF	N/A	LM-Merger: A workflow for merging logical models with an application to gene regulation
LM-Merg并：一种用于合并逻辑模型的流程，应用于基因调控	Li, L. X.	PDF	N/A	LM-Merger: A workflow for merging logical models with an application to gene regulation
通过工程改造的甲烷八叠球菌（Methanosarcina acetivorans）从一碳和二碳化合物中生产倍半萜烯红没药烯。	Mentrup, A.	PDF	N/A	Production of the sesquiterpene bisabolene from one- and two carbon compounds in an engineered Methanosarcina acetivorans
利用扩散磁共振成像技术在体绘制人类大脑皮层微观结构图	Sadikov, A.	PDF	N/A	Mapping the Microstructure of Human Cerebral Cortex In Vivo with Diffusion MRI
生物信息学：整合阴性对照以获得优质数据	van Nues, R. W.	PDF	N/A	Bio-informatics: Integrate negative controls to get the good data
轴突特异性微管调控驱动感觉神经元轴突的不对称再生	Costa, A. C.	PDF	N/A	Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons
冰与气：年轻北美鹅掌楸叶片中冻融栓塞与冻结扩散的可视化	Johnson, K. M.	PDF	N/A	Ice and air: Visualisation of freeze-thaw embolism and freezing spread in young L. tulipifera leaves
使用基于模型的fMRI技术，将视觉对比敏感度和视觉损失在整个视野范围内进行映射。	Chow-Wing-Bom, H. T.	PDF	N/A	Mapping Visual Contrast Sensitivity and Vision Loss Across the Visual Field with Model-Based fMRI
叶片大小决定了玉米中由损伤和植食性昆虫诱导的挥发性物质的释放。	Waterman, J. M.	PDF	N/A	Leaf size determines damage- and herbivore-induced volatile emissions in maize
iModMix：多组学数据的综合模块分析	Narvaez-Bandera, I. Y.	PDF	N/A	iModMix: Integrative Module Analysis for Multi-omics Data
对涡虫再生特异性的比较分析揭示了轴向cWnt信号梯度对组织极性的贡献。	Cleland, J. P.	PDF	N/A	A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient.
规范模型揭示了前青春期精神病理学维度中明显的皮层异常。	Deng, Q.	PDF	N/A	Normative models reveal distinct cortical abnormalities to dimensions of psychopathologies in preadolescents
葡萄糖-6-磷酸酶对于果蝇精子的细胞器重组、能量代谢和运动能力是必需的。	Hedjazi, S.	PDF	N/A	Glucose-6-phosphatase is required for organelle reorganization, energy metabolism and motility of Drosophila sperm
玉米及相关物种中生殖屏障的分子进化	Cryan, E.	PDF	N/A	Molecular evolution of a reproductive barrier in maize and related species
系统生物学的通用微分方程：当前状态与开放问题	Philipps, M.	PDF	N/A	Universal differential equations for systems biology: Current state and open problems
使用AlphaFold2预测肽的结构构象	Ille, A. M.	PDF	N/A	Prediction of peptide structural conformations with AlphaFold2
多组学分析揭示了跨多种多发性神经病变的人类腓肠神经特征	Heming, M.	PDF	N/A	Multi-omic characterization of human sural nerves acrosspolyneuropathies
介导视交叉上核昼夜节律同步的功能性脑连接组	Nikhil, K. L.	PDF	N/A	The Functional Connectome Mediating Circadian Synchrony in the Suprachiasmatic Nucleus
从整合的转录组数据集中推断基因-通路关联：一种用于四膜虫的交互式基因网络浏览器	Bertagna, M. A.	PDF	N/A	Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for Tetrahymena thermophila
伤寒沙门氏菌的伤寒毒素在急性伤寒热期间引发了宿主的抗菌反应。	Srour, S.	PDF	N/A	Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever
轴突起始段几何形态的可变性及其对海马锥体细胞功能的影响	Stevens, N. A.	PDF	N/A	Variability of axon initial segment geometry and its impact on hippocampal pyramidal cell function
在鱼类多样性中，基因表达对免疫刺激的宏观进化变化	Flanagan, B. A.	PDF	N/A	Macroevolutionary changes in gene expression response to an immune stimulus across the diversity of fishes
当蝙蝠仅依赖回声定位时，如何从拥挤的群体中离开 - 一种建模方法	Mazar, O.	PDF	N/A	How bats exit a crowded colony when relying on echolocation only - a modeling approach
CAR-T细胞疗法临床试验的临床前模型预测价值：一项系统综述和荟萃分析	Andreu-Sanz, D.	PDF	N/A	Predictive value of preclinical models for CAR-T cell therapy clinical trials: a systematic review and meta-analysis
协同神经回路与新颖性及目标导向行为的关联	Elliott, B. L.	PDF	N/A	Synergistic Neural Circuits for Novelty and Goal-Directed Behavior
神经元功能中的高阶相互作用：从基因到生物物理模型中的离子电流	Reva, M.	PDF	N/A	Higher-Order Interactions in Neuronal Function: From Genes to Ionic Currents in Biophysical Models
尽管人口数量有所恢复，但白头海雕的基因组仍在持续退化。	Fontsere, C.	PDF	N/A	Persistent genomic erosion in whooping cranes despite demographic recovery
生存蓝图：蓝斑蜻蜓作为城市适应的典范	Tolman, E. R.	PDF	N/A	The Blueprint for Survival: The Blue Dasher Dragonfly as a Model for Urban Adaptation
生存蓝图：蓝斑蜻蜓作为城市适应的典范	Tolman, E. R.	PDF	N/A	The Blueprint for Survival: The Blue Dasher Dragonfly as a Model for Urban Adaptation
前所未有的雌性偏倚突变在指猴中出现	Wang, R. J.	PDF	N/A	Unprecedented female mutation bias in aye-ayes
探索多拷贝质粒适应性动力学的系统：拷贝数和突变率在进化结果中的作用	Pisera, A.	PDF	N/A	A System to Explore the Adaptive Dynamics of Multicopy Plasmids: The Role of Copy Number and Mutation Rate in Evolutionary Outcomes
蚊子根据微孢子虫感染的动态进行自我治疗。	Zeferino, T. G.	PDF	N/A	Mosquitoes self-medicate according to the dynamics of a microsporidian infection
控制蝴蝶银色虹彩的适应性多态性的遗传基础	Livraghi, L.	PDF	N/A	Genetic basis of an adaptive polymorphism controlling butterfly silver iridescence
保存的Peromyscus属物种标本头部和耳廓形态的变异及其对听觉功能的启示	Sergott, C. E.	PDF	N/A	VARIATION IN HEAD AND PINNA MORPHOLOGY OF PRESERVED PEROMYSCUS SPP. SPECIMENS AND IMPLICATIONS FOR AUDITORY FUNCTION
在非洲大猿类物种形成早期，片段重复的不完全谱系分选定义了人类2号染色体的融合位点。	Jiang, X.	PDF	N/A	Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciation
空间药物不对称性调控抗性进化下的表型多样性-迁移关系	Hu, Z.	PDF	N/A	Spatial drug asymmetry modulates phenotypic diversity-migration relationships under resistance evolution
GPCRchimeraDB：一个用于协助设计嵌合G蛋白偶联受体（GPCRs）的数据库	Crauwels, C.	PDF	N/A	GPCRchimeraDB: A database of chimeric G-Protein Coupled Receptors (GPCRs) to assist their design
多层组织中干细胞命运决定的生物力学	Sahu, P.	PDF	N/A	Biomechanics of stem cell fate decisions in multilayered tissues
自闭症谱系障碍个体中，后侧脾状复合体表现出非典型的场景选择性	Persichetti, A. S.	PDF	N/A	Atypical scene-selectivity in the retrosplenial complex in individuals with autism spectrum disorder
细胞分裂依赖的HMR-1/钙粘蛋白扭转调控秀丽隐杆线虫中首次左右对称性破缺事件	Khor, M. J.	PDF	N/A	Cytokinesis-dependent twisting of HMR-1/Cadherin regulates the first left-right symmetry-breaking event in Caenorhabditis elegans
对灵长类胚胎体中直系同源细胞类型的鉴定和比较显示了标记基因转移性的局限性。	Jocher, J.	PDF	N/A	Identification and comparison of orthologous celltypes from primate embryoid bodies shows limits of marker gene transferability
一种CRISPR相关Rossman折叠环核酸酶与腺苷脱氨酶的融合蛋白通过别构作用将ATP转化为ITP	Whyms, C. T.	PDF	N/A	A CRISPR-associated Rossman-fold Ring Nuclease and Adenosine Deaminase Fusion Allosterically Converts ATP to ITP
在果蝇卵子发生过程中，发育调控的肌动蛋白-微管交叉对话	Chou, W.-C.	PDF	N/A	Developmentally regulated actin-microtubule crosstalk in Drosophila oogenesis
半胱氨酸反应性共价RNF4配体CCW16通过激活ROS信号传导诱导AML细胞发生铁死亡。	Mueller, S.	PDF	N/A	The cysteine-reactive covalent RNF4 ligand CCW16 induces ferroptosis in AML cells by activation of ROS signaling
形态发生约束在类原肠胚发育中的作用：对小鼠原肠形成的影响	Fiuza, U.-M.	PDF	N/A	Morphogenetic constrains in the development of gastruloids: implications for mouse gastrulation
在斑马鱼胚胎发生过程中利用Ace2N-mNeon探索生物电	Wu, Z.	PDF	N/A	Exploring Bioelectricity with Ace2N-mNeon during Zebrafish Embryogenesis
粘附调控的胶质微环境力学调节神经干细胞的增殖潜能	Cristina, A. S.	PDF	N/A	Adhesion-Controlled Mechanics of the Glial Niche Regulate Neural Stem Cell Proliferative Potential
珊瑚礁栖息地的复杂性降低，导致当地光照的可用性和多样性减少。	Brambilla, V.	PDF	N/A	Coral reef habitat complexity decreases and diversifies local availability of light
端粒到端粒基因组组装揭示了沃尔巴克氏体驱动的性特异性人口统计学，并对锯蜂中的费希尔原理提出了挑战	Zhang, M.	PDF	N/A	Telomere-to-Telomere Genome Assembly Uncovers Wolbachia-Driven Sex-Specific Demography and Challenges Fisher's Principle in a Sawfly
因果关系的考虑可以决定机器学习辅助的全基因组关联研究（GWAS）的效用。	Mukherjee, S.	PDF	N/A	Causal considerations can determine the utility of machine learning assisted GWAS
一个优化的方案，用于在微藻Chlamydomonas reinhardtii中相对定量ATP和多磷酸盐	Israelievitch, E.	PDF	N/A	An optimised protocol for the relative quantification of ATP and polyphosphates in the microalga Chlamydomonas reinhardtii
一个使用大型语言模型（LLMs）进行SARS-CoV-2蛋白质序列比较的无监督框架	Littlefield, S. B.	PDF	N/A	An unsupervised framework for comparing SARS-CoV-2 protein sequences using LLMs
SeuratIntegrate：一个R包，用于简化与Seurat集成方法的使用	Specque, F.	PDF	N/A	SeuratIntegrate: an R package to facilitate the use of integration methods with Seurat
基于肿瘤内微生物组的肿瘤生存指数在泛癌尺度上预测免疫相互作用和药物敏感性	Gao, Y.	PDF	N/A	Intra-tumor microbiome-based tumor survival indices predict immune interaction and drug sensitivity on pan-cancer scale
ggrain - 一个用于绘制雨云图的 ggplot2 扩展	Judd, N.	PDF	N/A	ggrain - a ggplot2 extension for raincloud plots
纵向评估轻度认知障碍向阿尔茨海默病痴呆的转化：来自神经心理学测试和电生理学的观察与机制	Dunstan, D. M.	PDF	N/A	Longitudinal assessment of the conversion of mild cognitive impairment into Alzheimer's dementia: Observations and mechanisms from neuropsychological testing and electrophysiology
支架蛋白CasL通过限制膜起泡来调节T细胞迁移。	Kurtz, L. A.	PDF	N/A	The scaffold protein CasL regulates T cell migration by restricting membrane blebbing
多尺度分析与功能验证：骨骼疾病细胞与遗传决定因素的研究	Chai, R. C.	PDF	N/A	Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease
脊椎动物分工的健身驱动力	Garcia-Ruiz, I.	PDF	N/A	Fitness drivers of division of labor in vertebrates
鞭毛虫鞭毛的近端部分发生了鞭毛内运输的选择性。	Alves, A. A.	PDF	N/A	Intraflagellar Transport Selectivity Occurs with the Proximal Portion of the Trypanosome Flagellum
IQCG的新型微管成核因子在人类中迅速进化，具有双重作用	YU, H.	PDF	N/A	Dual roles of IQCG, a novel microtubule nucleation factor rapidly evolving in humans
IQCG的新型微管成核因子的双重作用，在人类中迅速进化	Liu, X.	PDF	N/A	Dual roles of IQCG, a novel microtubule nucleation factor rapidly evolving in humans
冷凝物作为翻译枢纽，协调多核细胞的生长。	Geisterfer, Z. M.	PDF	N/A	Condensates act as translation hubs to coordinate multinucleate cell growth
对裸鼹鼠细胞中储存操纵钙进入途径的功能性表征	Drugachenok, P.	PDF	N/A	Functional characterization of the store-operated calcium entry pathway in naked mole-rat cells
果蝇依赖复制的组蛋白基因在细胞周期调控下的转录暂停	Kemp, J. P.	PDF	N/A	Cell cycle-regulated transcriptional pausing of Drosophila replication-dependent histone genes
成纤维蛋白FMNL2在黑色素瘤细胞对基质硬度的反应中起作用。	Clugston, J. D.	PDF	N/A	The formin FMNL2 plays a role in the response of melanoma cells to substrate stiffness
PERK信号通过促进增殖来维持内质网应激下造血干细胞池的完整性。	Zheng, M.	PDF	N/A	PERK Signaling Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation
C端HSP90二聚化小分子抑制剂通过调节自噬，并与mTOR抑制剂协同作用，杀灭顺铂耐药的癌细胞。	David, C.	PDF	N/A	Small-molecule inhibitor of C-terminal HSP90 dimerization modulates autophagy and functions synergistically with mTOR inhibition to kill cisplatin-resistant cancer cells
FAF2是一种双功能调节因子，参与过氧化物酶体稳态和饱和脂质反应的调控。	Kim, C.	PDF	N/A	FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses
结果导向显微技术：细胞生物学的闭环光遗传控制	Passmore, J.	PDF	N/A	Outcome-Driven Microscopy: Closed-Loop Optogenetic Control of Cell Biology
TMEM55A介导的PI5P信号通路调控α细胞肌动蛋白解聚及胰高血糖素分泌	Liu, X.	PDF	N/A	TMEM55A-mediated PI5P signaling regulates α-cell actin depolymerization and glucagon secretion
二甲双胍抑制衰老和老化过程中染色质片段的核外排	Kumazawa, T.	PDF	N/A	Metformin inhibits nuclear egress of chromatin fragments in senescence and aging
硅藻中主要转运蛋白载体亚家族的动态重定位与分化表达	Liu, S.	PDF	N/A	Dynamic relocalization and divergent expression of a major facilitator carrier subfamily in diatoms
HNF4alpha在β细胞中的敲除效果是年龄和性别依赖性的。	Villaca, C. B.	PDF	N/A	The effect of HNF4alpha knockout in beta cells is age and gender dependent
EMC复合体在裂殖酵母的线粒体呼吸和静止状态中起着关键作用。	Berraquero, M.	PDF	N/A	A key role of the EMC complex for mitochondrial respiration and quiescence in fission yeasts
利用氢/氘交换质谱法探究Pup连接酶PafA的结构异质性	Plourde, A.	PDF	N/A	Probing the structural heterogeneity of Pup ligase PafA using H/D exchange mass spectrometry
OST组件RPN1是一种新型调控因子，能够调节IRE1的RNase活性，并与多个不同的IRE1和PERK复合体相互作用。	Larburu, N.	PDF	N/A	OST component RPN1 is a novel regulator of IRE1 RNase activity that interacts with multiple distinct IRE1 and PERK complexes
基于结构的嵌合流感血凝素设计以诱导跨组免疫	Castro, K. M.	PDF	N/A	Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity
交联介导的相互作用组分析揭示了PHD2-HIF1α相互作用热点及PHD2在调控蛋白质类泛素化中的作用	Ouyang, H.	PDF	N/A	Crosslinking-mediated Interactome Analysis Identified PHD2-HIF1α Interaction Hotspots and the Role of PHD2 in Regulating Protein Neddylation
水稻中α-扩张蛋白前体的结构表征与功能评估	Nayem, R. I.	PDF	N/A	Structural Characterization and Functional Assessment of the Alpha-Expansin Precursor in Oryza sativa
机械应力引发解剖结构变化，促进番茄提前开花，并提高产量，这一过程涉及乙烯和生长素。	Castro-Estrada, J.	PDF	N/A	Mechanical stress induces anatomical changes, tomato early flowering, and increased yield involving ethylene and auxins
探索苔藓植物小立碗藓（Marchantia polymorpha）中胞间连丝的形成与渗透性	Hsu, C.-Y.	PDF	N/A	Exploring The Formation And Permeability Of Plasmodesmata In The Liverwort, Marchantia polymorpha
普通菜豆中的非特异性磷脂酶C，PvNPC4，调控根和根瘤的发育。	Pacheco, R.	PDF	N/A	The non-specific phospholipase C of common bean PvNPC4 modulates roots and nodule development
关于Piper chaba（Chui jhal）的全面研究：植物化学成分与抗氧化作用	Kundu, M.	PDF	N/A	A Comprehensive Study of Piper chaba (Chui jhal): Phytochemistry and Antioxidant Effects
玉米自交系在昼夜转录模式上表现出等位基因变异。	Gage, J. L.	PDF	N/A	Maize inbreds show allelic variation for diel transcription patterns
观赏植物普通耧斗菜的基因组序列揭示了黄酮类生物合成基因组	Friedhoff, R.	PDF	N/A	Genome sequence of the ornamental plant Aquilegia vulgaris reveals the flavonoid biosynthesis gene repertoire
玉米粗糙胚乳6是一种预测的RNA解旋酶，对于miRNA加工和胚乳细胞模式形成是必需的。	Yang, T.	PDF	N/A	Maize rough endosperm6 is a predicted RNA helicase required for miRNA processing and endosperm cell patterning
假定的禾本科特异性EXO70类群的新功能化	Bergum, M.	PDF	N/A	Putative neofunctionalization of a Poales-specific EXO70 clade
在拟南芥中，内珠被控制胚囊发育和种子形状。	Mody, T. A.	PDF	N/A	The inner integument controls embryo sac development and seed shape in Arabidopsis thaliana
心脏成纤维细胞的细胞各向异性性由YAP依赖的细胞收缩性和细胞外基质（ECM）生成决定。	Pereira-Sousa, D.	PDF	N/A	Cardiac fibroblasts cellular anisotropy is determined by YAP-dependent cellular contractility and ECM production
COMMD3在胞内体运输中的独立于指挥官的功能	Squiers, G. T.	PDF	N/A	A Commander-independent function of COMMD3 in endosomal trafficking
NRBP1假激酶在渗透压应激下结合并激活WNK通路	Amnekar, R.	PDF	N/A	NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress
秀丽隐杆线虫中唯一必需的低分子量原肌球蛋白同工型对其咽肌功能至关重要。	Kimmich, M. J.	PDF	N/A	The sole essential low molecular weight tropomyosin isoform of Caenorhabditis elegans is essential for pharyngeal muscle function.
植物GORK K+通道调控中对称性转换的结构与机制洞察	Li, Q.-y.	PDF	N/A	Structural and Mechanistic Insights into Symmetry Conversion in Plant GORK K+ Channel Regulation
功能性大脑连接与音乐训练：从音乐感知中的脑电图相位同步中获得的见解	Provorova, A.	PDF	N/A	Functional Brain Connectivity and Musical Training: Insights from EEG Phase Synchronization During Music Perception
以患者来源的诱导多能干细胞为模型研究额颞叶痴呆病理	Barber, D. L.	PDF	N/A	Patient-derived Induced Pluripotent Stem Cells as a Model to Study Frontotemporal Dementia Pathologies
腹侧前运动皮层内的多稳态双峰感知编码	Andrade-Ortega, B.	PDF	N/A	Multi-Stable Bimodal Perceptual Coding within the Ventral Premotor Cortex
老龄化、阿尔茨海默病病理和APOE4对老年人纵向功能连接和情景记忆的不同影响	Fischer, L.	PDF	N/A	Differential effects of aging, Alzheimer's pathology, and APOE4 on longitudinal functional connectivity and episodic memory in older adults
多巴胺能对身份预测误差的反应依赖于眶额皮质和海马体的程度不同。	Takahashi, Y.	PDF	N/A	Dopaminergic responses to identity prediction errors depend differently on the orbitofrontal cortex and hippocampus
AmpliPiper：一种多用途的扩增子测序分析工具，适用于多基因位点的DNA条形码分析	Bertelli, A.	PDF	N/A	AmpliPiper: A versatile amplicon-seq analysis tool for multilocus DNA barcoding
单细胞表示的因果解耦与可控反事实生成	Gao, Y.	PDF	N/A	Causal disentanglement for single-cell representations and controllable counterfactual generation
DDI2缺乏通过恶化细胞生存条件抑制肝癌进展	Liu, K.	PDF	N/A	Deficiency of DDI2 suppresses liver cancer progression byworsening cell survival conditions
通过积极记忆回忆提升吹奏管乐器的主观表现成就：交感神经激活与情绪效价的影响	Watanabe, A.	PDF	N/A	Enhanced Subjective Performance Achievement in Wind Instrument Playing through Positive Memory Recall: Effects of Sympathetic Activation and Emotional Valence
热量限制：减轻神经元损伤的一种潜在方法：来自阿尔茨海默病细胞模型的启示	Sharma, A.	PDF	N/A	Caloric restriction: A potential approach for mitigating neuronal damage: Lesson from cellular model of Alzheimer Disease
麦哲伦企鹅在复杂的海流环境中平衡导航与觅食机会	Gunner, R. M.	PDF	N/A	Magellanic penguins balance navigation with foraging opportunities in complex current regimes
mmVelo：一种用于估计跨多模态的细胞状态依赖性动力学的深度生成模型	Nomura, S.	PDF	N/A	mmVelo: A deep generative model for estimating cell state-dependent dynamics across multiple modalities
计算建模评估PKP2基因治疗对致心律失常性心肌病心室传导特性的影响	Ostini, A.	PDF	N/A	Computational Modeling of Effects of PKP2 Gene Therapy on Ventricular Conduction Properties in Arrhythmogenic Cardiomyopathy
基于脑电图的长时警觉性和注意力涣散评估：采用用户中心频率标记方法	Ladouce, S.	PDF	N/A	EEG-based Assessment of Long-Term Vigilance and Lapses of Attention using a User-Centered Frequency-Tagging Approach
脑静脉血流通过硬脑膜淋巴管调节脑液清除	El Kamouh, M.-R.	PDF	N/A	Cerebral Venous Blood Flow Regulates Brain Fluid Clearance via Dural Lymphatics
白细胞介素-1β 在心律失常性心肌病进展中起驱动作用	Penna, V. R.	PDF	N/A	Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy
一种新的Tensin1异构体促进肌动蛋白纤维组装，以实现高效的红细胞前体细胞核排出	Coffin, M.	PDF	N/A	A novel isoform of Tensin1 promotes actin filament assembly for efficient erythroblast enucleation
热选择改变了蓝贻贝幼体的遗传多样性和表现。	Nascimento-Schulze, J. C.	PDF	N/A	Thermal selection shifts genetic diversity and performance in blue mussel juveniles
非桑蚕丝素功能化提高了对齐聚吡咯-蚕丝复合材料中的电荷转移效率，以促进电刺激神经突生长	Borah, R.	PDF	N/A	Non-mulberry silk fibroin functionalization enhances charge-transfer efficiency in aligned polypyrrole-silk composites for electrically stimulated neurite outgrowth
Cnot4杂合性减轻了高脂饮食引起的小鼠肥胖，并损害了PPARγ介导的脂肪细胞分化。	Yamaguchi, T.	PDF	N/A	Cnot4 heterozygosity attenuates high fat diet-induced obesity in mice and impairs PPARγ-mediated adipocyte differentiation.
DKC1介导的rRNA假尿苷化通过靶向hnRNP A1来维持IRES依赖性翻译和ATF4驱动的代谢适应。	Gupta, A.	PDF	N/A	DKC1-mediated pseudouridylation of rRNA targets hnRNP A1 to sustain IRES-dependent translation and ATF4-driven metabolic adaptation
B型肾插入细胞中V-ATPase相互作用蛋白Tldc2的敲除会损害尿液碱化。	Eaton, A. F.	PDF	N/A	Knockout of the V-ATPase interacting protein Tldc2 in B-type kidney intercalated cells impairs urine alkalinization
岛叶皮层编码任务对齐	Niediek, J.	PDF	N/A	Insular cortex encodes task alignment
使用深度度量学习对发育中的大脑进行功能指纹识别：一项ABCD研究	Xu, R.	PDF	N/A	Functional fingerprinting for the developing brain using deep metric learning: an ABCD study
雄性C. elegans单核神经元转录组分析揭示了性别特异性和性别共享行为的调控因子	Morillo, K. S.	PDF	N/A	Single-Nucleus Neuronal Transcriptional Profiling of Male C. elegans Uncovers Regulators of Sex-Specific and Sex-Shared Behaviors
Mdivi-1对氧化低密度脂蛋白诱导的人单核细胞代谢改变、炎症反应及泡沫细胞形成的影响	Mosalmanzadeh, N.	PDF	N/A	Modulatory Effects of Mdivi-1 on OxLDL-Induced Metabolic Alterations, Inflammatory Responses, and Foam Cell Formation in Human Monocytes
计算建模揭示了胡须轻弹脑电图背后的生物学机制。	Tharayil, J. J.	PDF	N/A	Computational modeling reveals biological mechanisms underlying the whisker-flick EEG
在外部干扰后，工作记忆中重新选择视觉和运动内容时的神经动力学	Gresch, D.	PDF	N/A	Neural dynamics of reselecting visual and motor contents in working memory after external interference
自私却健忘的大脑：在低血糖期间，大脑氧代谢保持稳定，但记忆巩固受损。	Bose, A.	PDF	N/A	The selfish yet forgetful brain: Stable cerebral oxygen metabolism during hypoglycemia but impaired memory consolidation
果蝇触角中光和隐花色素对气味感觉的控制	Thakur, D.	PDF	N/A	Control of odor sensation by light and cryptochrome in the Drosophila antenna
基于机器学习的共定位与扩散分析的胰岛素类似物在细胞内的多样化运输	Bleshoy, S. V.	PDF	N/A	Diverse Intracellular Trafficking of Insulin Analogs byMachine Learning-based Colocalization and DiffusionAnalysis
预测昼夜节律调节对高血压大鼠肾脏转运蛋白的影响	zheng, k.	PDF	N/A	Predicted Effect of Circadian Regulation of Renal Transporters in a Hypertensive Rat
慢性行为和癫痫发作结果：小鼠实验性创伤性脑损伤及伴随的肺炎克雷伯菌肺部感染	Rewell, S. S.	PDF	N/A	Chronic Behavioral and Seizure Outcomes following Experimental Traumatic Brain Injury and Comorbid Klebsiella pneumoniae Lung Infection in Mice
新一代减肥药物抑制大脑奖励回路	Godschall, E. N.	PDF	N/A	A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs
针对SNAPTM-TIL的临床前概念验证：一种个性化、新一代的肿瘤浸润淋巴细胞治疗平台	Halder, T. G.	PDF	N/A	Preclinical Proof of Concept for SNAPTM-TIL: a personalized, next-generation tumor-infiltrating lymphocyte therapy platform
在觅食任务中，大黄蜂能够灵活地根据感官信息内容调整学习和决策策略。	Spaethe, J.	PDF	N/A	Bumblebees flexibly adjust learning and decision strategies to sensory information content in a foraging task
用于三维神经元培养中记录活动的应力触发型柔性微电极阵列	Serra, J.	PDF	N/A	Stress-actuated Flexible Microelectrode Arrays for Activity Recording in 3D Neuronal Cultures
PepMSND：整合多层次特征工程和综合数据库以提升体内/体外肽血液稳定性预测	Haomeng, H.	PDF	N/A	PepMSND: Integrating Multi-level Feature Engineering and Comprehensive Databases to Enhance in vivo/in vitro Peptide Blood Stability Prediction
在阿尔茨海默病中使用内省变分自编码器进行多模态规范建模	Kumar, S.	PDF	N/A	Multimodal normative modeling in Alzheimer Disease with introspective variational autoencoders
纹状体的两个组成部分，即纹状小体和基质，嵌入在很大程度上不同的静息状态功能网络中。	Sadiq, A.	PDF	N/A	The striatal compartments, striosome and matrix, are embedded in largely distinct resting state functional networks
使用福尔马林固定、石蜡包埋的肿瘤样本，对基于成像的单细胞分辨率空间转录组学分析平台进行比较	Ozirmak Lermi, N.	PDF	N/A	Comparison of imaging-based single-cell resolution spatial transcriptomics profiling platforms using formalin-fixed, paraffin-embedded tumor samples
特定的SOX10增强子元件调控黑色素瘤中的表型可塑性和药物抗性	DeGeorgia, S. N.	PDF	N/A	Specific SOX10 enhancer elements modulate phenotype plasticity and drug resistance in melanoma
适应胱氨酸限制应激通过翻译上调氧化磷酸戊糖途径促进胰腺导管腺癌（PDAC）肿瘤生长和转移。	Li, Y.	PDF	N/A	Adaptation to cystine limitation stress promotes PDAC tumor growth and metastasis through translational upregulation of OxPPP
重复暴露于5G-3.5 GHz信号不会改变成年雄性小鼠的行为，但会改变其大脑内的基因表达。	Lameth, J.	PDF	N/A	Repeated head-exposures to a 5G-3.5 GHz signal do not alter behavior but modify intracerebral gene expression in adult male mice.
RasGRP1信号通过调控c-Maf表达，引导发育中的γδ胸腺细胞向γδT17谱系分化。	Joannou, K.	PDF	N/A	RasGRP1 Signalling Programs Developing γδ-Thymocytes towards the γδT17 Lineage Through Control of c-Maf Expression
使用非侵入性生物监测评估未驯化的北绒毛蛛猴（Brachyteles hypoxanthus）的群体规模和人口构成	Kaizer, M. C.	PDF	N/A	Assessing group size and the demographic composition of unhabituated northern muriqui (Brachyteles hypoxanthus) using non-invasive biomonitoring
直立蛇的姿势控制	Hoffmann, L. A.	PDF	N/A	Postural control in an upright snake
CCL17-CCR4轴在突变STAT6介导的复发/难治性弥漫大B细胞淋巴瘤微环境重塑和治疗抵抗中起关键作用。	Abraham, M. J.	PDF	N/A	The CCL17-CCR4 axis is critical for mutant STAT6-mediated microenvironmental remodelling and therapeutic resistance in Relapsed/Refractory Diffuse Large B Cell Lymphoma
野生大山雀离婚的时间和社会后果：一种现象学方法	Abraham, A. D.	PDF	N/A	Timing and social consequences of divorce in wild great tits: a phenomenological approach
miRScore：一种快速且精确的微RNA验证工具	Vanek, A.	PDF	N/A	miRScore: a rapid and precise microRNA validation tool
针对急性髓性白血病中FBXO21介导的p85α泛素化的小分子靶向研究	Dobish, K. K.	PDF	N/A	Small molecule targeting of FBXO21 mediated p85αubiquitylation in acute myeloid leukemia
Notch信号通路维持着肝细胞癌中一种类似祖细胞的亚型。	Seidel, K.	PDF	N/A	Notch signaling maintains a progenitor-like subclass of hepatocellular carcinoma
鬃毛囊地鼠（Chaetodipus hispidus）听觉脑干反应中的性别差异	Joseph, L.	PDF	N/A	Sex Differences in Auditory Brainstem Responses in the Hispid Pocket Mouse (Chaetodipus hispidus)
关注注意力：高关注度位点作为语言模型中蛋白质家族和功能的指示器	Nayar, G.	PDF	N/A	Paying Attention to Attention: High Attention Sites as Indicators of Protein Family and Function in Language Models
开始与停止 - 一个用于交互式模拟控制的PhysiCell和PhysiBoSS 2.0插件	Smeriglio, R.	PDF	N/A	Start&Stop - a PhysiCell and PhysiBoSS 2.0 add-on for interactive simulation control
感觉毛细胞中转导通道门控力的电控制。	Joliot, A.	PDF	N/A	Electrical control of the transduction channels' gating force in sensory hair cells.
整合多组学揭示前驱期和特发性帕金森病肠道微生物群功能的改变	Villette, R.	PDF	N/A	Integrated multi-omics highlights alterations of gut microbiome functions in prodromal and idiopathic Parkinson's disease
在果蝇中，繁殖和对宏量营养素的偏好与生物学年龄或时间年龄的关系不同。	Lushchak, O.	PDF	N/A	Reproduction and preference to macronutrients have different relations to biological or chronological age in Drosophila
有证据表明，听觉感知判断具有系统性——然而这种节奏性又与任务和运动相关——的节奏性。	Fabio, C.	PDF	N/A	Evidence for systematic - yet task- and motor-contingent - rhythmicity of auditory perceptual judgements
MIND-Map：用于估计大脑动态状态的综合工具箱	Khodaei, M.	PDF	N/A	MIND-Map; A Comprehensive Toolbox for Estimating Brain Dynamic States
非热量甜味剂与葡萄糖共同作用影响下丘脑葡萄糖感应诱导的胰岛素分泌及通过神经细胞代谢的食物再摄取：体内与体外研究方法	HAYDAR, J.	PDF	N/A	Non-Caloric Sweeteners combined with glucose affect hypothalamic glucose sensing-induced insulin secretion, food re-intake through neuronal cellular metabolism: An in vivo and in vitro approaches
是什么使得人类皮层锥体神经元在功能上如此复杂	Aizenbud, I.	PDF	N/A	What makes human cortical pyramidal neurons functionally complex
与多发性硬化症相关的促炎分子会改变人类少突胶质细胞系细胞的发育。	Blaszczyk, G. J.	PDF	N/A	Pro-Inflammatory Molecules Implicated in Multiple Sclerosis Divert the Development of Human Oligodendrocyte Lineage Cells
肌肉协同结构和激活模式的变化是力场适应、保留和泛化的基础。	Herzog, M.	PDF	N/A	Changes in Muscle Synergy Structure and Activation Patterns Underlie Force Field Adaptation, Retention, and Generalization
PinkyCaMP 是一种基于 mScarlet 的钙传感器，具有卓越的亮度、光稳定性和多重成像能力。	Fink, R.	PDF	N/A	PinkyCaMP a mScarlet-based calcium sensor with exceptional brightness, photostability, and multiplexing capabilities
在短暂缺血后，Na+/Ca2+交换器触发海马齿状细胞轴突初始段短暂性破坏。	Serra, C.	PDF	N/A	Na+/Ca2+ exchanger triggers transient disruption of axon initial segments in hippocampal granule cells after brief ischemia.
运动限制的束缚应激通过多巴胺依赖的神经可塑性抑制雄性果蝇的求偶行为。	Sato, T.	PDF	N/A	Confinement stress with movement restriction suppresses male courtship in Drosophila through dopamine-dependent neuroplasticity
基于快速有限元法的经颅磁刺激电场计算	Cao, F.	PDF	N/A	Fast FEM-based Electric Field Calculations for Transcranial Magnetic Stimulation
与年龄相关的功能平衡能力变化可预测多感官整合过程中的α波活动	Pepper, J. L.	PDF	N/A	Age-Related Changes in Functional Balance Ability Predict Alpha Activity During Multisensory Integration
一项关于优秀阅读者与不良阅读者脑电图的探索性比较研究	Alvarez-Alonso, M. J.	PDF	N/A	An Exploratory EEG Comparison of Good and Bad Readers
量化体感传入类型及其变化对疼痛敏感性的贡献：在小鼠行为过程中使用经皮光遗传学刺激	Xie, Y.-F.	PDF	N/A	Quantifying the contribution of somatosensory afferent types and changes therein to pain sensitivity using transcutaneous optogenetic stimulation in behaving mice
保持眼、头和手的协调：在连续动作任务中快速协调的视觉运动行为	Schroeger, A.	PDF	N/A	Keeping Your Eye, Head, and Hand on the Ball: Rapidly Orchestrated Visuomotor Behavior in a Continuous Action Task
青少年饮酒会以性别特异性的方式导致长期抑制反应和眶额-纹状体活动的改变。	McCane, A.	PDF	N/A	Adolescent alcohol consumption produces long term alterations in response inhibition and orbitofrontal-striatal activity in a sex-specific manner
视网膜平铺片上神经节细胞的分子与空间分析：多样性、地形分布及血管周特性	Tsai, N. Y.	PDF	N/A	Molecular and spatial analysis of ganglion cells on retinal flatmounts: diversity, topography, and perivascularity
调节腓肠肌常见突触输入和运动单位募集阈值：踝关节位置的影响	Yu, X. S.	PDF	N/A	Modulation of Common Synaptic Inputs and Motor Unit Recruitment Threshold in TricepsSurae Muscles: Effects of Ankle Position
在超急性期缺血性卒中中快速的长程突触重塑	Chen, H.	PDF	N/A	Rapid long-range synaptic remodeling in hyperacute ischemic stroke
神经元中E2F4DN的表达通过TrkB信号通路恢复了纯合5xFAD小鼠的成年神经发生。	Lozano-Urena, A.	PDF	N/A	Neuronal expression of E2F4DN restores adult neurogenesis in homozygous 5xFAD mice via TrkB signaling
球面投影对脑图自旋测试的影响	Bazinet, V.	PDF	N/A	The effect of spherical projection on spin tests for brain maps
在自然主义虚拟环境中进行自由观看时，研究与扫视启动锁定的脑电图（EEG）特征，以揭示面部感知。	Nolte, D.	PDF	N/A	Investigating saccade-onset locked EEG signatures of face perception during free-viewing in a naturalistic virtual environment
从尖峰神经网络到可解释的动力学：一个扩散近似框架	Mohammadi, N.	PDF	N/A	From spiking neuronal networks to interpretable dynamics: a diffusion-approximation framework
赖氨酸去乙酰化抑制剂逆转TDP-43的错误定位，并与阿瑞莫醇联合使用改善神经肌肉病理	Scozzari, S.	PDF	N/A	Lysine deacetylation inhibition reverses TDP-43 mislocalization and in combination with arimoclomol ameliorates neuromuscular pathology
星形胶质细胞在神经元活动中的特征：基于机器学习的识别方法	Pirola, J. P.	PDF	N/A	Astrocytic Signatures in Neuronal Activity: A Machine Learning-Based Identification Approach
个体阿尔法频率预测时间感知敏感度	Morrow, A.	PDF	N/A	Individual Alpha Frequency Predicts the Sensitivity of Time Perception
静息状态和任务状态下白质内在连接网络的证据：一项大规模研究与模板	Itkyal, V. S.	PDF	N/A	Evidence for white matter intrinsic connectivity networks at rest and during a task: a large-scale study and templates
CDNF通过直接结合未折叠蛋白反应传感器PERK和IRE1α来拯救人类诱导多能干细胞衍生的多巴胺神经元。	Kovaleva, V.	PDF	N/A	CDNF rescues human iPSCs-derived dopamine neurons through direct binding to unfolded protein response sensors PERK and IRE1α
在体人类神经突交换成像（NEXI）在500 mT/m扩散梯度下	Chan, K.-S.	PDF	N/A	In vivo human neurite exchange imaging (NEXI) at 500 mT/m diffusion gradients
清醒恒河猴经颅磁刺激的皮层兴奋性评估：从募集曲线中获得的转化见解	Padanyi, A.	PDF	N/A	Assessment of cortical excitability in awake rhesus macaques with transcranial magnetic stimulation: translational insights from recruitment curves
追踪斑马鱼尾鳍肌肉的发育起源	Abe, G.	PDF	N/A	Tracing of the developmental origin of the caudal fin muscle in zebrafish
棕色变色龙（Anolis sagrei）的产卵前发育	Weberling, A.	PDF	N/A	Pre-oviposition development of the brown anole (Anolis sagrei)
自然单克隆自身抗体针对SLE患者的HERV-K102包膜-跨膜蛋白，能够选择性地消除自身反应性免疫细胞和癌细胞。	Gong, Q.	PDF	N/A	Natural monoclonal autoantibodies against HERV-K102 Envelope-TM from SLE patients selectively eliminate autoreactive immune cells and cancer cells
肌肉内脂肪组织在物理上限制了肌肉功能的恢复。	Norris, A. M.	PDF	N/A	Intramuscular adipose tissue physically restricts functional muscle recovery
一种利用流式细胞术鉴定美洲大蠊（Periplaneta americana (L.)）血细胞亚群相对丰度和功能能力的方法	Boyer-Millander, F. J.	PDF	N/A	A flow cytometric approach to identifying the relative abundance and functional capacities of hemocyte subsets in the American cockroach, Periplaneta americana (L.)
RNA测序揭示了男性和女性绒毛外滋养层细胞中常染色体基因表达差异的发育起始。	Shannon, M. J.	PDF	N/A	RNA sequencing reveals the developmental onset of autosomal gene expression differences in male and female extravillous trophoblasts
超长测序技术用于解析人类免疫球蛋白重链位点的连续单体型	Gornitzka, M. B.	PDF	N/A	Ultra-long sequencing for contiguous haplotype resolution of the human immunoglobulin heavy chain locus
稀有生境、稀有物种和入侵捕食者突显了科罗拉多河流域管理复杂性	Hossack, B. R.	PDF	N/A	RARE HABITATS, RARE SPECIES, AND INVASIVE PREDATORS HIGHLIGHT MANAGEMENT COMPLEXITIES IN THE COLORADO RIVER SYSTEM
森林栖息地和以森林为主的景观与具有与光敏感性相关的视觉特征的熊蜂物种有关。	Bartholomee, O.	PDF	N/A	Forest habitat and forest dominated landscapes are associated with bumblebee species with visual traits related to light sensitivity
外生菌根树木的功能性状影响其对周围土壤有机质性质的影响	Edwards, J. D.	PDF	N/A	Functional traits of ectomycorrhizal trees influence their effects on surrounding soil organic matter properties
比较转录组学揭示了在初始宿主定殖过程中，植物病原菌与内生菌之间的不同真菌策略。	Moonjely, S.	PDF	N/A	Comparative transcriptomics reveal contrasting fungal strategies in a plant pathogen versus an endophyte during initial host colonization
体外生物膜形成仅部分预测有益的荧光假单胞菌对根际病原体的保护作用。	Liu, Y.	PDF	N/A	In vitro biofilm formation only partially predicts beneficial Pseudomonas fluorescens protection against rhizosphere pathogens
野生社会性哺乳动物中主要组织相容性复合体两类的特征分析：条纹獴	Schubert, N.	PDF	N/A	Characterization of both major histocompatibility complex classes in a wild social mammal: the banded mongoose
利用PacBio技术对油橄榄（Olea europaea L. subsp. europaea）栽培品种‘Frantoio’和‘Leccino’进行基因组组装，揭示了与盐胁迫相关的关键基因在主要结构上的差异。	Sebastiani, L.	PDF	N/A	PacBio genome assembly of Olea europaea L. subsp. europaea cultivars 'Frantoio' and 'Leccino' reveal main structural differences in key genes related to salt stress
评估预训练数据集大小和多样性对单细胞基础模型性能的影响	DenAdel, A.	PDF	N/A	Evaluating the role of pre-training dataset size and diversity on single-cell foundation model performance
DNA甲基化在衰老过程中的集体动态变化	Hashtroud, A.	PDF	N/A	Collective dynamics of DNA methylation during ageing
比目鱼（Scophthalmus maximus）胚胎发生的表观基因组学	Aramburu, O.	PDF	N/A	Epigenomics of embryogenesis in turbot (Scophthalmus maximus)
人口比较显示，坦噶尼喀湖丽鱼科鱼类新亮丽鲷（Neolamprologus brevis）中，更多的社会互动与更大的脑容量相关。	Ma, B.	PDF	N/A	Population comparisons reveal more social interactions are correlated with larger brains in the Lake Tanganyikan cichlid Neolamprologus brevis
描述肌萎缩侧索硬化症（ALS）的SOD1G93A小鼠模型中运动功能的性别依赖性和解剖学上的衰退	Shelest, O.	PDF	N/A	Delineating sex-dependent and anatomic decline of motor functions in the SOD1G93A mouse model of amyotrophic lateral sclerosis
物理相互作用驱动蜜蜂集体调节温度的行为	Lambert, C. E.	PDF	N/A	Physical Interactions Drive Collective Thermoregulatory Behavior in Honey Bees
光交联26S蛋白酶体基底亚复合体的重组表达	Yori Restrepo, S.	PDF	N/A	Recombinant Expression of Photo-crosslinkable 26S Proteasome Base Subcomplex
可穿戴螺旋超声贴片用于糖尿病神经性疼痛的外周神经超声调控	Pu, C.	PDF	N/A	A Wearable Spiral Ultrasound Patch for Focused Ultrasound Peripheral Neuromodulation of Diabetic Neuropathic Pain
使用锚定细胞片工程制造的肌肉特异性ECM纤维在体积性肌肉损失的大鼠模型中支持组织再生	Shahin-Shamsabadi, A.	PDF	N/A	Muscle-Specific ECM Fibers Made with Anchored Cell Sheet Engineering Support Tissue Regeneration in Rat Models of Volumetric Muscle Loss
通过从人类细胞图谱推断基因网络来增强人类相互作用组，以进行疾病预测	Sung, E.	PDF	N/A	Augmenting the human interactome for disease prediction through gene networks inferred from human cell atlas
高维中介分析以阐明代谢物在PFAS暴露与妊娠期SARS-CoV-2 IgG减少之间的关联中的作用	Guan, H.	PDF	N/A	High-dimensional mediation analysis to elucidate the role of metabolites in the association between PFAS exposure and reduced SARS-CoV-2 IgG in pregnancy
基于空间多组学的鼠标前脑区域特异性分子特征及胆碱能神经元亚型分类的综合分析	Chen, Y.	PDF	N/A	Mouse Forebrain Region-specific Molecular Characteristics and Cholinergic Neurons Subtyping: An Integrated Analysis Based on Spatial Multi-omics
scMusketeers: 通过模块化自动编码器解决细胞类型注释不平衡和批次效应减少问题	Collin, A.	PDF	N/A	scMusketeers: Addressing imbalanced cell type annotation and batch effect reduction with a modular autoencoder
通过单细胞转录组学、整体转录组学和实验验证揭示的1型糖尿病免疫机制	Gao, W.	PDF	N/A	Immune mechanisms of type 1 diabetes revealed by single-cell transcriptomics, bulk transcriptomics, and experimental validation
Plasmo3Net：一种基于卷积神经网络的算法，用于检测薄血涂片图像中的疟原虫	Owoloye, A.	PDF	N/A	Plasmo3Net: A Convolutional Neural Network-Based Algorithm for Detecting Malaria Parasites in Thin Blood Smear Images
一个针对影响动物种群的新发传染病的实时预测框架	Theng, M.	PDF	N/A	A real-time forecasting framework for emerging infectious diseases affecting animal populations
量化DIA-MS数据集中之前未被量化的约75-95%的肽段	Saxena, G.	PDF	N/A	Quantifying the ~75-95% of Peptides in DIA-MS Datasets that were not Previously Quantified
Echidna：一种用于量化影响表型可塑性的基因剂量效应的贝叶斯框架	Fan, J. L.	PDF	N/A	Echidna: A Bayesian framework for quantifying gene dosage effect impacting phenotypic plasticity
利用荧光共振能量转移（FRET）在工程化黄色和青色蛋白之间进行淀粉样纤维的定量检测	Moustouka, C.	PDF	N/A	Quantitative Detection of Amyloid Fibrils using Fluorescence Resonance Energy Transfer (FRET) Between Engineered Yellow and Cyan Proteins
使用分子动力学模拟解码温度对未结合配体的温度感应腺嘌呤核开关的构象稳定性和有序性的影响	Das, S.	PDF	N/A	Decoding the effect of temperatures on conformational stability and order of the ligand unbound thermo-sensing adenine riboswitch using molecular dynamics simulation
使用原子模拟深入研究α-突触核蛋白P1结构域的热响应相行为	Chakraborty, S.	PDF	N/A	Insight into the Thermo-responsive Phase Behavior of P1 Domain of α-synuclein using Atomistic Simulations
关于巴西东部拉戈阿圣塔中全新世时期一种小型食果蝙蝠的注记	Chahud, A.	PDF	N/A	NOTE ON A SMALL FRUIT-EATING BAT FROM THE MIDDLE HOLOCENE OF LAGOA SANTA, EASTERN BRAZIL
CoREST复合物抑制剂corin能够减少非典型畸胎瘤横纹肌样瘤异种移植模型中的肿瘤生长，促进细胞分化，并延长寿命。	Geethadevi, A.	PDF	N/A	The CoREST complex inhibitor, corin, leads to decreased tumor growth, increased cellular differentiation and extended lifespan in atypical teratoid rhabdoid tumor xenograft models
拟除虫菊酯类杀虫剂溴氰菊酯会干扰胃肠道中的神经肽和单胺信号传导通路。	White, A. C.	PDF	N/A	The pyrethroid insecticide deltamethrin disrupts neuropeptide and monoamine signaling pathways in the gastrointestinal tract
一个三维体外模型再现了体内特征，并揭示了儿童急性淋巴细胞白血病中药物耐受性增加的现象。	Kanari, M.	PDF	N/A	A three-dimensional ex vivo model recapitulates in vivo features and unravels increased drug resistance in childhood acute lymphoblastic leukemia
评估了氧化锌纳米颗粒介导的Aframomum citratum（C. Pereira）K. Schum（姜科）在Wistar大鼠中的抗炎作用	Eya'ane Meva, F.	PDF	N/A	Anti-inflammatory assessment of zinc oxide nanoparticles mediated Aframomum citratum (C. Pereira) K. Schum (Zingiberaceae) in Wistar rats
PRMT1介导的代谢重编程促进白血病发生	Su, H.	PDF	N/A	PRMT1-Mediated Metabolic Reprogramming Promotes Leukemogenesis
CRISPR-Cas9 RALA敲除与重建。RALA S194磷酸化在RAS依赖性和RAS非依赖性癌症中的检测与作用。	Konde, M.	PDF	N/A	CRISPR-Cas9 RALA knockout and reconstitution. Detection and role of RALA S194 phosphorylation in RAS-dependent and RAS-independent cancers.
高通量靶向药物筛选用于治疗NF1相关的高级别胶质瘤，这些肿瘤存在ATRX缺陷	Dubey, S.	PDF	N/A	High-Throughput Targeted Drug Screening for NF1-associated High-Grade Gliomas with ATRX Deficiency
G蛋白失活作为成瘾治疗的一种机制	Neiswanger, C.	PDF	N/A	G protein Inactivation as a Mechanism for Addiction Treatment
果蝇视叶中的差异时间滤波	Borst, A.	PDF	N/A	Differential temporal filtering in the fly optic lobe
在意识状态改变期间，楔前叶的功能梯度减弱	Lyu, D.	PDF	N/A	Diminished functional gradient of the precuneus during altered states of consciousness
在阿尔茨海默病小鼠模型中，海马区过度表达肌肉因子Irisin的行为和代谢效应	Borukhin, J. A.	PDF	N/A	Behavioral and metabolic effects of extended hippocampal overexpression of the myokine Irisin in an Alzheimers Disease mouse model
通过皮质和周围躯体感觉刺激调节运动皮质可塑性	Bao, S.	PDF	N/A	Modulating Motor Cortex Plasticity via Cortical and Peripheral Somatosensory Stimulation
锥体细胞和中间神经元在尖波纹波的作用下被强烈地重新激活。	Javed, M. H.	PDF	N/A	cfos principal cells and interneurons are strongly reactivated by sharp wave ripples
瞬时频率：动态脑因果网络的新型功能生物标志物	Tang, H.	PDF	N/A	Instantaneous Frequency: A New Functional Biomarker for Dynamic Brain Causal Networks
AOSLO光栅扫描视觉刺激对视网膜ON和OFF通路的非对称激活	Patterson, S. S.	PDF	N/A	Asymmetric Activation of Retinal ON and OFF Pathways by AOSLO Raster-Scanned Visual Stimuli
时间分辨的睡眠阶段神经振荡：与睡眠质量和衰老的关联	Passaro, A. D.	PDF	N/A	Time-Resolved Neural Oscillations Across Sleep Stages: Associations with Sleep Quality and Aging
伏隔核核心中的A2A阳性神经元调节努力程度	Shoemaker, C. T.	PDF	N/A	A2A-positive neurons in the nucleus accumbens core regulate effort exertion
使用预训练的编码器-解码器框架，从直接皮质记录中进行自然语音的重新合成	Li, J.	PDF	N/A	Natural speech re-synthesis from direct cortical recordings using a pre-trained encoder-decoder framework
慢性背痛小鼠模型的神经免疫机制	Goins, A. E.	PDF	N/A	Neuroimmune mechanisms of a mouse model of chronic back pain
考虑到更复杂的囊泡池模型，对量子突触参数的估计	Bornschein, G.	PDF	N/A	Estimates of quantal synaptic parameters in light of more complex vesicle pool models
同步三维模式化多种中枢神经系统祖细胞生成具有广泛轴向特征的运动神经元	Buchner, F.	PDF	N/A	Synchronous 3D patterning of diverse CNS progenitors generates motor neurons of broad axial identity
在人类视觉工作记忆中，区分θ和α振荡与非周期性神经活动的贡献	van Engen, Q.	PDF	N/A	Dissociating Contributions of Theta and Alpha Oscillations from Aperiodic Neural Activity in Human Visual Working Memory
通过背景去除的单光子钙成像连续预测小鼠压杆运动学参数	Li, M.	PDF	N/A	Continuous Prediction of Mice Lever-Pressing Kinematic Parameters by Background Removed Single-photon Calcium Images
糖尿病对结核病病理生理学的影响：AGE-RAGE轴和糖化蛋白的作用	Panda, S.	PDF	N/A	Implications of diabetes mellitus on pathophysiology of Tuberculosis: Role of AGE-RAGE Axis and Glycated Proteins
脓毒症引起人类造血干细胞/祖细胞（HSPCs）的长期重编程，并驱动脓毒症幸存者的髓系失调。	De Zuani, M.	PDF	N/A	Sepsis induces long-term reprogramming of human HSPCs and drives myeloid dysregulation in sepsis survivors
基于巨大芽孢杆菌（Priestia megaterium）ILBB592的生物肥料提高了磷肥的施用效率，积极影响大豆的营养和产量，并改变了根际细菌群落。	Torres, P.	PDF	N/A	Priestia megaterium ILBB592 based biofertilizer increases the efficiency of phosphorus fertilization, positively affects soybean nutrition and yield and modifies the rhizospheric bacterial community
一种细菌NLR相关蛋白能够识别多种不相关的噬菌体触发因素，以感知感染。	Kibby, E. M.	PDF	N/A	A bacterial NLR-related protein recognizes multiple unrelated phage triggers to sense infection
野生狒狒肠道微生物群中真核生物在不同季节和社会群体间的组成	Chege, M.	PDF	N/A	Eukaryotic composition across seasons and social groups in the gut microbiota of wild baboons
狂犬病糖蛋白的深度突变扫描确定了突变约束和抗体逃逸突变	Aditham, A. K.	PDF	N/A	Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations
METTL7A通过减轻氧化应激来提高牛体细胞核移植胚胎的发育能力	Zhu, L.	PDF	N/A	METTL7A improves bovine IVF embryo competence by attenuating oxidative stress
斑马鱼中的原肠胚形成需要由NADPH氧化酶产生的活性氧物种来调节囊泡运输。	Ramirez Corona, A.	PDF	N/A	Epiboly in zebrafish requires reactive oxygen species produced by NADPH oxidases for the regulation of vesicular trafficking
海星Patiria miniata培养技术的进展	Barone, V.	PDF	N/A	Advances in culturing of the sea star Patiria miniata
使用人源类躯干结构（hTLS）模拟体节与神经管之间的共同发育	Makwana, K.	PDF	N/A	Modelling co-development between somites and neural tube with human Trunk-like Structures (hTLS)
降水耐受性决定了印度西高止山脉留鸟的垂直迁移策略。	Akshay, V. A.	PDF	N/A	Precipitation tolerance determines elevational migration strategies of resident birds of the Western Ghats of India.
Gloger法则如何预测鸟类对近红外和中红外辐射的吸收？	Lee, T.	PDF	N/A	How does Gloger's rule predict near- and mid-infrared radiation in birds?
利用环境DNA（eDNA）探索食果性相互作用：以木瓜（Carica papaya）和菠萝（Ananas comosus）为例	Banerjee, P.	PDF	N/A	Harnessing Environmental DNA (eDNA) to Explore Frugivorous Interactions: A Case Study in Papaya (Carica papaya) and Pineapple (Ananas comosus)
广泛遗传检测控制猫遗传性多囊肾病	Ukawa, H.	PDF	N/A	Widespread genetic testing control inherited polycystic kidney disease in cats
由LINE-1逆转录转座子引起的染色体重排和不稳定性	Mendez-Dorantes, C.	PDF	N/A	Chromosomal rearrangements and instability caused by the LINE-1 retrotransposon
用于早期检测猫退行性关节疾病的加速度计衍生分类器	Montout, A.	PDF	N/A	Accelerometer-derived classifiers for early detection of degenerative joint disease in cats
物质的重要性：原材料影响着僧帽猴的石器工具性能	O'Malley, T. D. R.	PDF	N/A	Material matters: raw material influences stone tool performance in capuchin monkeys
蚂蚁根据过去、即将来临和预测的逆境进行适应性决策	Notomi, Y.	PDF	N/A	Adaptive decision-making by ants in response to past, imminent, and predicted adversity
Dairy DigiD ~ 一种基于深度学习的非侵入式生物识别系统，利用Detectron2技术对奶牛进行身份识别	Mahato, S.	PDF	N/A	Dairy DigiD ~ A Deep Learning-Based, Non-Invasive Biometric Identification System for Dairy Cattle Using Detectron2
StayRose：一种通过遗传密码扩展实现红移的光稳定StayGold衍生物	Scott, W.	PDF	N/A	StayRose: a photostable StayGold derivative red-shifted by genetic code expansion
解析复杂遗传模式特征：从基因面板的角度	Szyda, J.	PDF	N/A	Unravelling traits with complex inheritance mode: a gene panel perspective
在存在拷贝数变异、非整倍体和多倍体生物的情况下进行短串联重复序列的基因分型	Verbiest, M. A.	PDF	N/A	Genotyping Short Tandem Repeats Across Copy Number Alterations, Aneuploidies, and Polyploid Organisms
dsRNAmax：一种用于安全有效作物保护的多靶点嵌合dsRNA设计工具	Fletcher, S. J.	PDF	N/A	dsRNAmax: a Multi-Target Chimeric dsRNA Designer for Safe And Effective Crop Protection
有机磷化合物的计算机毒性评估：基于密度泛函理论和分子对接研究其与人体血清白蛋白（HSA）的相互作用	Singh, T.	PDF	N/A	In Silico Toxicity Assessment of Organophosphates: A DFT and Molecular Docking Study on Their Interaction with Human Serum Albumin (HSA)
发现通路蛋白折叠中间体揭示了折叠与错误折叠之间的动力学竞争	Luan, Q.	PDF	N/A	Discovery of an on-pathway protein folding intermediate illuminates the kinetic competition between folding and misfolding
机械力调节PD-1的抑制功能	Chen, H.	PDF	N/A	Mechanical force regulates the inhibitory function of PD-1
通过3D葡聚糖水凝胶培养调节细胞变形性以调控小鼠脾脏和肝脏中间充质干细胞的微循环	Zhu, X.	PDF	N/A	Modulating Cellular Deformability via 3D Dextran Hydrogel Cultivation to Regulate the Microcirculation of Mesenchymal Stem Cells in Murine Spleen and Liver
嗜酸性粒细胞通过抑制促肿瘤的SPP1+巨噬细胞分化来限制结直肠癌的转移。	Handler, K.	PDF	N/A	Eosinophils restrict CRC metastasis by inhibiting pro-tumorigenic SPP1+ macrophage differentiation
利用组织病理学图像进行结直肠癌亚型分类的深度学习驱动个性化医疗	Truong Le, T.	PDF	N/A	Deep Learning-Driven Subtype Classification of Colorectal Cancer Using Histopathology Images for Personalized Medicine
优化用于福尔马林固定人组织中肠神经系统免疫组织化学评估的实验方案。	Hong, S. M.	PDF	N/A	Optimization of protocols for immunohistochemical assessment of enteric nervous system in formalin fixed human tissue.
NRBP1和TSC22D蛋白通过调节WNK通路，影响远端卷曲小管的生理功能。	Magana-Avila, G. R.	PDF	N/A	NRBP1 and TSC22D proteins impact distal convoluted tubule physiology through modulation of the WNK pathway
肝细胞肉毒碱棕榈酰转移酶1a的失活降低了小鼠中含载脂蛋白B的脂蛋白水平。	Helsley, R. N.	PDF	N/A	Hepatic Inactivation of Carnitine Palmitoyltransferase 1a Lowers Apolipoprotein B Containing Lipoproteins in Mice
基于动力学模型的多株酿酒酵母菌株工程改造提高了对香豆酸的生产	Narayanan, B.	PDF	N/A	Kinetic-model-guided engineering of multiple S. cerevisiae strains improves p-coumaric acid production
在山区生存：温度和海拔对喜马拉雅山脉中的悬停蝇（Eristalis tenax）具有相反的生理影响。	Gharpure, G.	PDF	N/A	Surviving in the mountains: Temperature and elevation have contrasting physiological effects on the hoverfly Eristalis tenax in the Himalayas
控制资源弹性	Solomyak, L.	PDF	N/A	The resource elasticity of control
大脑图谱显示了整体认知功能及其与神经生物学皮质特征的空间相关性	Moodie, J. E.	PDF	N/A	Brain maps of general cognitive function and spatial correlations with neurobiological cortical profiles
周围神经的生理活动影响神经对外加电刺激的输出反应：一项体内研究	Madden, L. R.	PDF	N/A	Physiological activity within peripheral nerves influences neural output in response to electrical stimulation: an in vivo study
中央脑网络在梳理过程中支撑身体部位的协调	Ozdil, P. G.	PDF	N/A	Centralized brain networks underlie body part coordination during grooming
成像跳舞的大脑：在双人舞蹈中解码感觉、运动和社会过程	Bigand, F.	PDF	N/A	Imaging the dancing brain: Decoding sensory, motor and social processes during dyadic dance
整合多系统环境因素以预测青少年大脑与行为	Ramduny, J.	PDF	N/A	Integrating multi-system environmental factors to predict brain and behavior in adolescents
视觉和前庭系统对垂直运动的处理：一项心理物理学研究	Delle Monache, S.	PDF	N/A	Visual and vestibular processing of vertical motion: a psychophysical study
一种基于低成本FPGA的用于校正堆叠的高速活体FLIM成像方法	Moros, F. V.	PDF	N/A	A low-cost FPGA-based approach for pile-up corrected high-speed in vivo FLIM imaging
裸盖菇素会导致大脑信号传导通路发生与性别、时间和剂量相关的改变。	Barnett, J. H.	PDF	N/A	Psilocybin causes sex, time, and dose dependent alterations in brain signaling pathways
导水管周围灰质超越失望，传递出对剩余奖励预期的持续信号。	Lee, H.	PDF	N/A	Periaqueductal gray passes over disappointment and signals continuity of remaining reward expectancy
减少的肠道BDNF-TrkB信号传导驱动糖皮质激素介导的胃肠动力障碍	Slosberg, J. S.	PDF	N/A	Reduced enteric BDNF-TrkB signaling drives glucocorticoid-mediated GI dysmotility
光遗传学抑制消除了感觉输入在大脑皮层的整合	Ambrosone, M.	PDF	N/A	Optogenetic inhibition quenches the integration of sensory input in the cortex
Wdr45基因突变导致早期运动功能障碍和广泛异常的轴突终末，这一现象在基于β-螺旋桨蛋白相关神经退行性疾病（BPAN）患者特征的小鼠模型中得到体现。	Meyerink, B. L.	PDF	N/A	Mutation in Wdr45 leads to early motor dysfunction and widespread aberrant axon terminals in a beta-propeller protein associated neurodegeneration (BPAN) patient-inspired mouse model
荧光寿命成像揭示了神经元中α-突触核蛋白种子聚集的机制	Ivey, P.-M. E.	PDF	N/A	Mechanisms of Alpha-Synuclein Seeded Aggregation in Neurons Revealed by Fluorescence Lifetime Imaging
二态神经网络结构使雄性C.elegans优先进行与性相关的行为	WANG, X.	PDF	N/A	Dimorphic Neural Network Architecture Prioritizes Sexual-related Behaviors in Male C.elegans
弗朗西斯菌新凶手菌（Francisella novicida）形成外膜管的过程涉及广泛的细胞膜修饰，并与VI型分泌系统的活动以及宿主吞噬体膜的改变密切相关。	Rashid, M.	PDF	N/A	Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and is linked with type VI secretion and alterations to the host phagosomal membrane
抗生素对Oct-TriA1的从头进化抗性	Chowdhury, F. R.	PDF	N/A	De novo evolution of antibiotic resistance to Oct-TriA1
一个完整的胶原蛋白IV荧光素敲入工具包揭示了基底膜中的-链多样性	Srinivasan, S.	PDF	N/A	A complete collagen IV fluorophore knock-in toolkit reveals -chain diversity in basement membrane
早期秀丽隐杆线虫胚胎中新蛋白质翻译的景观与调控	Shukla, Y.	PDF	N/A	Landscape and regulation of new protein translation in the early C. elegans embryo
牛胚外内胚层细胞的建立	Ming, H.	PDF	N/A	Establishment of bovine extraembryonic endoderm cells
温暖或明亮 - 昆虫传粉者在微生境中对温度和光照的利用	Bartholomee, O.	PDF	N/A	Warm or bright - temperature and light microhabitat use in insect pollinators
微孢子虫寄生虫利用宿主的机制	Silva, L. M.	PDF	N/A	Mechanisms of host exploitation by a microsporidian parasite
量子介导的细菌信号传导能否解释适应性突变？	Ross, P.	PDF	N/A	Could Quantum-Mediated Bacterial Signaling Explain Adaptive Mutation?
衰老会破坏卵巢周期中的时空协调性。	Lan, T. C. T.	PDF	N/A	Aging disrupts spatiotemporal coordination in the cycling ovary
染色体外DNA介导的谷氨酰胺合成酶2（GS2）扩增使苋菜（Amaranthus palmeri）获得草铵膦抗性。	Noguera, M. M.	PDF	N/A	Extrachromosomal DNA-mediated glutamine synthetase 2 (GS2) amplification enables glufosinate resistance in Amaranthus palmeri
亚聚类、标记识别以及植物单细胞RNA-seq数据分析中受原生质体化影响的多组学整合	Yao, J.	PDF	N/A	Sub-clustering, marker identification and multi-omics integration influenced by protoplasting in plant scRNA -seq data analysis
SurFlex显微镜：测量表面结合生物分子的柔性	Chorlay, A.	PDF	N/A	SurFlex Microscopy: Measuring Flexibility of Surface-Tethered Biomolecules
FLASH放疗与常规剂量率放疗在同种异体小鼠乳腺癌模型中的疗效比较	Melemenidis, S.	PDF	N/A	Effectiveness of FLASH vs conventional dose rate radiotherapy in a model of orthotopic, murine breast cancer
一种新型泛I类葡萄糖转运蛋白抑制剂DRB18在体外和体内与紫杉醇联合使用对人非小细胞肺癌表现出协同效应。	Shriwas, P.	PDF	N/A	A novel pan class-I glucose transporter inhibitor DRB18 exhibits synergistic effects in vitro and in vivo with paclitaxel against human non-small cell lung cancer
MCM2通过促进促血管生成的cardiosome信号传导，介导了心肌梗死后心脏保护作用。	Alam, P.	PDF	N/A	MCM2 mediates post-MI cardioprotection by promoting the pro-angiogenic cardiosome signaling
蛋白质组学分析揭示了在表达PINTAC肽的帕金森病表型毒素模型中，PERK/ISR与MAPK1在翻译控制中的复杂相互作用。	NALLUR, G. N.	PDF	N/A	Proteomic analysis reveals complex interactions between PERK/ISR and MAPK1 in translational control in a phenotypic toxin model of Parkinsons disease expressing PINTAC peptides.
运动皮层和纹状体中神经动力学层次结构在自然行为中的表现	Xing, D. Y.	PDF	N/A	Neural dynamics hierarchy in motor cortex and striatum across naturalistic behaviors
我该去哪里？利用卷积神经网络解码场景处理与视觉空间记忆交互的时间神经动态	Naveilhan, C.	PDF	N/A	Where do I go? Decoding temporal neural dynamics of scene processing and visuospatial memory interactions using CNNs
脑微观结构的寿命规范建模	Reina, J. E. V.	PDF	N/A	Lifespan Normative Modeling of Brain Microstructure
海草相关炭疽菌（Colletotrichum sp.）的基因组简化可能与其适应海洋单子叶植物宿主有关。	Ettinger, C. L.	PDF	N/A	Genomic streamlining of seagrass-associated Colletotrichum sp. may be related to its adaptation to a marine monocot host
在病例对照全基因组关联研究中，r2的数学界限及效应大小的影响	Paye, S. M.	PDF	N/A	Mathematical bounds on r2 and the effect size in case-control genome-wide association studies
探索罕见变异间的基因相互作用揭示了易受复杂疾病影响的基因网络	Jiang, H.	PDF	N/A	Exploring Genetic Interactions with Rare Variants Reveals Gene Networks Susceptible to Complex Diseases
# BioRxiv 2024-12-16 Papers

标题	作者	PDF链接	代码仓库	Title
适应重金属污染环境的过程是通过对预先存在的遗传变异进行选择来进行的。	Wright, K. M.	PDF	N/A	Adaptation to heavy-metal contaminated environments proceeds via selection on pre-existing genetic variation
CanSig：一种用于单细胞RNA-Seq数据中恶性状态发现基准测试的工具	Barkmann, F.	PDF	N/A	CanSig: a tool for benchmarking malignant state discovery in single-cell RNA-Seq data
NMDA受体调控神经网络中的活动层次结构：层次结构控制失效导致学习障碍、分离现象和精神病	Zhou, Y.	PDF	N/A	NMDA Receptors Control Activity Hierarchy in Neural Network: Loss of Control in Hierarchy Leads to Learning Impairments, Dissociation, and Psychosis
植物基因组的高效组装：以毛茛属（毛茛科）为例探讨其进化意义	Karbstein, K.	PDF	N/A	Efficient assembly of plant genomes: A case study with evolutionary implications in Ranunculus (Ranunculaceae)
缺氧诱导因子在RSV感染期间对临床疾病和病毒复制控制的贡献存在差异。	Morris, D. R.	PDF	N/A	Hypoxia-inducible-factors differentially contribute to clinical disease and the control of viral replication during RSV infection
使用超分辨率超声定位显微镜对小鼠深部脑微血管进行纵向清醒成像	Wang, Y.	PDF	N/A	Longitudinal Awake Imaging of Deep Mouse Brain Microvasculature with Super-resolution Ultrasound Localization Microscopy
测序、对柳叶菜科植物叶绿体基因组进行从头组装，以及在柳叶菜科家族内的比较分析	Barloy-Hubler, F.	PDF	N/A	Sequencing, de novo assembly of Ludwigia plastomes, and comparative analysis within the Onagraceae family
多样性杂交小鼠中寿命可变性的分子结构	Hackett, S. R.	PDF	N/A	The Molecular Architecture of Variable Lifespan in Diversity Outbred Mice
建模低维交互脑网络揭示了人类认知的组织原则	Sanz Perl, Y.	PDF	N/A	Modelling low-dimensional interacting brain networks reveals organising principle in human cognition
压电依赖的基质硬度监测产生瞬时细胞，用于修复基底膜	Stricker, A. M.	PDF	N/A	Piezo-dependent surveillance of matrix stiffness generates transient cells that repair the basement membrane
肌萎缩侧索硬化症眶额皮层单核转录组图谱及基于深度学习的可变多聚腺苷酸化机制解码	McKeever, P. M.	PDF	N/A	Single-nucleus transcriptome atlas of orbitofrontal cortex in amyotrophic lateral sclerosis with a deep learning-based decoding of alternative polyadenylation mechanisms
通过获得自调控的超基因进化	VanKuren, N. W.	PDF	N/A	Supergene evolution via gain of auto-regulation
ZNRF3/RNF43的丧失在癌症中释放了EGFR	Yue, F.	PDF	N/A	Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
无靶向的代谢物比率对逐像素成像作为质谱成像中生物医学发现的新工具	Cheng, H.	PDF	N/A	Untargeted Pixel-by-Pixel Imaging of Metabolite Ratio Pairs as a Novel Tool for Biomedical Discovery in Mass Spectrometry Imaging
CELSR1在外部区域中由一个紧凑模块调控的结构基础	Bandekar, S. J.	PDF	N/A	Structural basis for regulation of CELSR1 by a compact module in its extracellular region
β-连环蛋白通过与经典RNA结合蛋白结合，在髓系细胞中与Wnt信号mRNA网络相关联。	Wagstaff, M.	PDF	N/A	β-Catenin associates with a Wnt signaling mRNA network in myeloid cells through canonical RBP binding.
电休克对齿状回颗粒神经元的功能、回路和转录组的影响	Santiago, A. N.	PDF	N/A	Effects of electroconvulsive shock on the function, circuitry, and transcriptome of dentate gyrus granule neurons
Vps5-Vps17 SNX-BAR蛋白与Retromer组装的分子基础	Chen, K.-E.	PDF	N/A	Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
海马位置细胞的动态伽马调制在θ序列的发展中占主导地位	Wang, N.	PDF	N/A	Dynamic Gamma Modulation of Hippocampal Place Cells Predominates Development of Theta Sequences
发现RdRp Thumb-1作为一种新型广谱抗病毒靶标家族以及MDL-001作为一种强效广谱抑制剂	Woods, V.	PDF	N/A	Discovery of RdRp Thumb-1 as a novel broad-spectrum antiviral family of targets and MDL-001 as a potent broad-spectrum inhibitor thereof
早期视觉皮层中的主动干扰抑制	Richter, D.	PDF	N/A	Proactive distractor suppression in early visual cortex
对隐藏的注意力优先图进行Ping操作：抑制需要注意力	Huang, C.	PDF	N/A	Pinging the Hidden Attentional Priority Map: Suppression Needs Attention
染毒蛙蝌蚪中糖皮质激素应激反应的早期发育	Surber, L. L.	PDF	N/A	Early development of the glucocorticoid stress response in dyeing poison frog tadpoles
小鼠和非人灵长类动物发育中的大脑的功能成像	ZHU, J.	PDF	N/A	Functional Imaging of Developing Brain in Mice and Non-Human Primates
RNA-TorsionBERT：利用语言模型进行RNA三维扭转角预测	Bernard, C.	PDF	N/A	RNA-TorsionBERT: leveraging language models for RNA 3D torsion angles prediction
VIPER：一种用于预测酶底物的通用模型	Campbell, M. J.	PDF	N/A	VIPER: A General Model for Prediction of Enzyme Substrates
Msp300（Nesprin）的一个独特同工型在脂肪细胞中组织了核周微管组织中心。	Morton, G. M.	PDF	N/A	A distinct isoform of Msp300 (Nesprin) organizes the perinuclear microtubule organizing center in adipocytes
无腔动物繁殖中的发育、再生和行为动态	Chandra, V.	PDF	N/A	Developmental, regenerative, and behavioral dynamics in acoel reproduction
使用深度学习方法建模伪对称溶质载体转运蛋白的替代构象状态	Swapna, G. V. T.	PDF	N/A	Modeling Alternative Conformational States of Pseudo-Symmetric Solute Carrier Transporters using Methods from Deep Learning
使用lr-kallisto进行长读长测序转录组定量	Loving, R. K.	PDF	N/A	Long-read sequencing transcriptome quantification with lr-kallisto
在酿酒酵母中，ATP合酶亚基复合体通过Novel If1机制防止ATP水解	Lerouley, O.	PDF	N/A	Novel If1 mechanism preventing ATP hydrolysis by the ATP synthase subcomplex in Saccharomyces cerevisiae
高阶（9阶）Ambisonics对声源定位的聚焦性及频谱重现误差对感知效果的影响	Zargarnezhad, N.	PDF	N/A	Focality of sound source placement by higher (9th) order ambisonics and perceptual effects of spectral reproduction errors
植物-真菌网络中信号传递与监测的演化	Scott, T. W.	PDF	N/A	The evolution of signalling and monitoring in plant-fungal networks
凝视反映了对明确决策的信心，同时依赖于一种独特的计算机制。	Stern, Y.	PDF	N/A	Gaze reflects confidence in explicit decisions while relying on a distinct computational mechanism
疼痛分布可以通过经典条件反射来确定。	Nastaj, J.	PDF	N/A	Pain distribution can be determined by classical conditioning
基因组组成可预测多倍体蝾螈对温度的生理反应	Burger, I.	PDF	N/A	Genome composition predicts physiological responses to temperature in polyploid salamanders
肌梭为运动序列提供灵活的感觉反馈。	Olson, W. P.	PDF	N/A	Muscle spindles provide flexible sensory feedback for movement sequences
肿瘤细胞的空间组织通过YAP信号传导引导EGFR/RAS/RAF通路对主要治疗产生抗性	Nakagawa, R.	PDF	N/A	Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling
一个针对环境16S rRNA牛津纳米孔测序数据进行改进分析的目标参考数据库	Philip, M.	PDF	N/A	A Targeted Reference Database for Improved Analysis of Environmental 16S rRNA Oxford Nanopore Sequencing Data
在“狗衰老项目”中，来自多样群体的狗的转座子DNA甲基化模式揭示了衰老差异。	Mariner, B. L.	PDF	N/A	DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project
细胞形状噪声强度调控EMT相关细胞扩展过程中形状变化的速度	Poenisch, W.	PDF	N/A	Cell shape noise strength regulates the rate of shape change during EMT-associated cell spreading
高表达的细胞壁基因有助于花萼大小的稳定性。	Hartasanchez, D. A.	PDF	N/A	Highly expressed cell wall genes contribute to robustness of sepal size
P23H视紫红质在ER中的聚集导致视杆光感受器中突触蛋白失衡	Thompson, S.	PDF	N/A	P23H rhodopsin aggregation in the ER causes synaptic protein imbalance in rod photoreceptors
估计并纠正单细胞RNA-seq数据中的指数跳跃误分配	Miao, L.	PDF	N/A	Estimating and correcting index hopping misassignments in single-cell RNA-seq data
线粒体ETF不足通过选择性优化癌症生物能量代谢来驱动肿瘤生长。	Papadopoli, D.	PDF	N/A	Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
在临床质子治疗系统的同步回旋加速器室内，对A549肺癌细胞和IMR90健康人体成纤维细胞进行体外FLASH照射。	Zazpe, A.	PDF	N/A	In vitro FLASH irradiation of A549 lung cancer cells and IMR90 healthy human fibroblasts in the synchrocyclotron room of a clinical proton therapy system
慢性感染SARS-CoV-2患者的宿主体内遗传多样性模式多样	Rutsinsky, N.	PDF	N/A	Diverse patterns of intra-host genetic diversity in chronically infected SARS-CoV-2 patients
重新评估爱泼斯坦-巴尔病毒（EBV）与美国乳腺癌之间的关联	Hu, C. C.	PDF	N/A	Reevaluating the Association Between Epstein-Barr Virus (EBV) and Breast Cancer in the United States
离开科学：38个经合组织国家生物学家的流失	Kwiek, M.	PDF	N/A	Leaving Science: Attrition of Biologists in 38 OECD Countries
不同的调控元件程序指导小鼠性腺发育过程中性别特异的支持细胞分化。	Stevant, I.	PDF	N/A	Divergent regulatory element programs steer sex-specific supporting cell differentiation along mouse gonadal development
用于晶体衍射数据质量评估的I/σI与{Rmerg, Rmeas, Rpim, CC1/2}关系图	Fu, Z.	PDF	N/A	I/σI vs {Rmerg, Rmeas, Rpim, CC1/2} for Crystal Diffraction Data Quality Evaluation
一种用于分类学的时光机	Davis-Richardson, A.	PDF	N/A	A Time Machine for Taxonomy
鉴定髓样蛋白激酶C-ε为一个新型抗动脉粥样硬化基因	Wells, A. T.	PDF	N/A	Identification of Myeloid Protein Kinase C - Epsilon as a Novel Atheroprotective Gene
鉴定髓样蛋白激酶C-ε为一个新型抗动脉粥样硬化基因	Wells, A. T.	PDF	N/A	Identification of Myeloid Protein Kinase C - Epsilon as a Novel Atheroprotective Gene
结构上不同的锰感应核糖开关适配体调控多种表达平台架构	Stephen, C.	PDF	N/A	Structurally distinct manganese-sensing riboswitch aptamers regulate diverse expression platform architectures
十八烷类作为珊瑚-腰鞭虫共生中的新兴脂质介质	Botana, M. T.	PDF	N/A	Octadecanoids as emerging lipid mediators in cnidarian-dinoflagellate symbiosis
使用OPM-MEG测量的听觉MMN的重测信度	Demko, L.	PDF	N/A	Test-retest reliability of auditory MMN measured with OPM-MEG
栖息地质量通过皮质醇影响西伯利亚鼯鼠（Pteromys volans）的肠道微生物群	Petrullo, L.	PDF	N/A	Habitat quality influences gut microbiota via cortisol in Siberian flying squirrels (Pteromys volans)
通过NMDA受体GluN2B羧基末端域的非离子型信号传导驱动树突棘的形态可塑性，并逆转小鼠海马中的脆性X综合征表型	Barnes, S. A.	PDF	N/A	Non-ionotropic signaling through the NMDA receptor GluN2B carboxy terminal domain drives morphological plasticity of dendritic spines and reverses fragile X phenotypes in mouse hippocampus
早期生活逆境介导了基底节-杏仁核回路功能障碍，这种功能障碍是慢性疼痛和焦虑的基础。	Borruto, A. M.	PDF	N/A	Early-life adversity mediates a thalamo-amgydalar circuit dysfunction underlying chronic pain and anxiety
PlexinA2、PlexinA4 和 NCAM 在发育中的海马苔藓纤维中具有多样化和位置特异性的作用	Zhao, X.-F.	PDF	N/A	Diverse and Location-Specific Roles of PlexinA2, PlexinA4, and NCAM in Developing Hippocampal Mossy Fibers
快速模拟血缘关系片段	Temple, S. D.	PDF	N/A	Fast simulation of identity-by-descent segments
一种简化的双质粒系统，用于使用光激活的CRISPR效应器对哺乳动物细胞进行正交基因表达控制	Garimella, S. S.	PDF	N/A	A simplified two-plasmid system for orthogonal control of gene expression using light-activated CRISPR effector for mammalian cells
黑色素瘤对免疫治疗的反应受B细胞衍生的细胞外囊泡调控	Al Hrout, A.	PDF	N/A	Melanoma Response to Immunotherapy is regulated by B Cell-Derived Extracellular Vesicles
眼球运动在人类海马中组织了兴奋性状态、信息编码和网络连接。	Leszczynski, M.	PDF	N/A	Eye movements organize excitability state, information coding and network connectivity in the human hippocampus
虚拟与现实世界模拟中的接近-回避偏差：来自实验设置系统性回顾的见解	Grasso-Cladera, A.	PDF	N/A	Approach-Avoidance Bias in Virtual and Real-World Simulations: Insights from a Systematic Review of Experimental Setups
从北到南：H1N1pdm09猪流感A病毒在意大利的传播动态	Giovanetti, M.	PDF	N/A	From North to South: Transmission Dynamics of H1N1pdm09 Swine Influenza A Viruses in Italy
特异性、长度和运气：罕见和常见变异关联研究如何优先考虑基因	Spence, J. P.	PDF	N/A	Specificity, length, and luck: How genes are prioritized by rare and common variant association studies
鉴定杜普伊特伦病的新的血浆蛋白质组学生物标志物	Hummer, B.	PDF	N/A	Identification of novel plasma proteomic biomarkers of Dupuytren Disease
构建多囊卵巢综合征中特定于颗粒细胞的ceRNA网络	Derevyanchuk, E.	PDF	N/A	Construction of a ceRNA network specific for granulosa cells in PCOS
人类组织中内含子保留数量性状位点的起源与意义	Park, E.	PDF	N/A	Origins and Implications of Intron Retention Quantitative Trait Loci in Human Tissues
巴西米纳斯吉拉斯州耳念珠菌的出现：基因组监测以指导快速公共卫生应对	Tome, L. M. R.	PDF	N/A	Emergence of Candida auris in Minas Gerais, Brazil: Genomic Surveillance to inform Rapid Public Health Responses
运动中的风险优化：从投掷中的运动和注视行为中获得的见解	Zahno, S.	PDF	N/A	Risk optimization during ongoing movement: Insights from movement and gaze behavior in throwing
慢性高强度间歇训练（HIIT）在青春期大鼠中进行的训练会导致可卡因条件性位置厌恶及ΔFosB的诱导。	Thanos, P. K.	PDF	N/A	Chronic High Intensity Interval Training (HIIT) exercise in adolescent rat's result in cocaine place aversion and ΔFosB induction
一个多尺度的电代谢大鼠新皮层电路模型揭示了衰老对中央皮层的影响	Farina, S.	PDF	N/A	A multiscale electro-metabolic model of a rat neocortical circuit reveals the impact of ageing on central cortical layers
tRNASer3的双重解码展示了核糖体解码中心的可塑性。	Krishnaswamy, S.	PDF	N/A	Doublet decoding of tRNASer3 demonstrates plasticity of ribosomal decoding center
实验性增温改变了湿润热带森林中的氮循环	Bartz, P. M.	PDF	N/A	Experimental Warming Alters Nitrogen Cycle in a Humid Tropical Forest
泥炭地恢复可以在所有时间尺度上提供气候变化缓解：一个英国案例研究	Zhang, X.	PDF	N/A	Peatland restoration can provide climate change mitigation over all time-scales: A UK case-study
不同果实特性沙棘品种的遗传多样性	Melnikova, N. V.	PDF	N/A	Genetic Diversity of Hippophae rhamnoides Varieties with Different Fruit Characteristics
受无序调控：磷酸化调节SRSF1域的可用性以促进剪接体成熟	Fargason, T. E.	PDF	N/A	Controlled by disorder: phosphorylation modulates SRSF1 domain availability for spliceosome maturation
探索在富含蓝藻的微生物群中同时生产聚羟基丁酸酯和胞外多糖	Gonzalez Flo, E.	PDF	N/A	Exploring simultaneous production of polyhydroxybutyrate and exopolysaccharides in cyanobacteria-rich microbiomes
使用图像引导光纤的结构光投影用于原位光生物制造	Chansoria, P.	PDF	N/A	Structured light projection using image guide fibers for in situ photo-biofabrication
用于密码子优化的预训练蛋白质语言模型	Pathak, S.	PDF	N/A	Pre-trained protein language model for codon optimization
评估Tropilaelaps mercedesae对多种合成杀螨剂的抗性水平。	Gill, M. C.	PDF	N/A	Assessment of the levels of resistance of Tropilaelaps mercedesae to a variety of synthetic miticide.
年轻和老年人在行走时对视觉干扰的内外平衡控制的敏感性	DiBianca, S. J.	PDF	N/A	SENSITIVITY OF MEDIAL/LATERAL BALANCE CONTROL TO VISUAL DISTURBANCES WHILE WALKING IN YOUNG AND OLDER ADULTS
电场方向对基于TMS的运动皮质映射的影响	Jing, Y.	PDF	N/A	Effects of Electric Field Direction on TMS-based Motor Cortex Mapping
衰老大脑中脉络丛体积减少的证据	Youh, R.-Y.	PDF	N/A	Evidence for reduced choroid plexus volume in the aged brain
基于数据非依赖采集（DIA）的无标记氧化还原蛋白质组学（DIALRP）揭示了新的氧化应激响应翻译因子	Kobayashi, D.	PDF	N/A	Data-independent acquisition (DIA)-based Label-free Redox Proteomics (DIALRP) Reveals Novel Oxidative Stress Responsive Translation Factors
基于数据非依赖采集（DIA）的无标记氧化还原蛋白质组学（DIALRP）揭示了新的氧化应激响应翻译因子	Kobayashi, D.	PDF	N/A	Data-Independent Acquisition (DIA)-Based Label-Free Redox Proteomics (DIALRP) Reveals Novel Oxidative Stress Responsive Translation Factors
非整倍体细胞的耗竭受到细胞间相互作用的影响。	Fusari, E.	PDF	N/A	Depletion of aneuploid cells is shaped by cell-to-cell interactions
在NLRP3炎症小体激活后，Gasdermin D介导了ATP的快速短暂释放，随后由ninjurin 1引发的溶细胞死亡。	Schachter, J.	PDF	N/A	Gasdermin D mediates a fast transient release of ATP after NLRP3 inflammasome activation before ninjurin 1-induced lytic cell death
鱼类精子上的守门人受体：探究精子与卵子的兼容性	Blaha, A.	PDF	N/A	Bouncer's receptor on sperm: Investigating sperm-egg compatibility in fish
使用贝叶斯推理量化CAR-T细胞对急性髓性白血病的性能	Shah, S.	PDF	N/A	Quantification of CAR T cell performance against acute myeloid leukemia using Bayesian inference
适应性塑造了小鼠视觉皮层（V1）中的表征几何结构，使其能够高效地编码环境信息。	Dipoppa, M.	PDF	N/A	Adaptation shapes the representational geometry in mouse V1 to efficiently encode the environment
密度依赖性阻碍了进化拯救。	Olazcuaga, L.	PDF	N/A	Density dependence impedes evolutionary rescue
生物入侵前沿的进化动力学	Poloni, S.	PDF	N/A	Evolutionary dynamics at the leading edge ofbiological invasions
通过配偶选择进行性选择何时会减少或夸大遗传变异：是否存在一个“求偶场悖论”？	Xu, K.	PDF	N/A	When does sexual selection through mate choice deplete versus exaggerate genetic variation: is there a lek paradox?
利用全基因组、线粒体DNA和单倍型区块来解析复杂的人口历史：以一种广泛混血的北极鱼类为例	Dallaire, X.	PDF	N/A	Leveraging whole genomes, mitochondrial DNA, and haploblocks to decipher complex demographic histories: an example from a broadly admixed arctic fish
ΔNP63 定义了小鼠胰腺中一种向外分泌方向分化的多能祖细胞亚群。	Coolens, K.	PDF	N/A	ΔNP63 defines an exocrine-committed multipotent progenitor subset in the murine pancreas
在北海微藻水华期间，异养细菌对有机磺酸盐的利用中的资源划分	Sidhu, C.	PDF	N/A	Resource partitioning in organosulfonate utilization by free-living heterotrophic bacteria during a North Sea microalgal bloom
在年轻健康成年人中，观察协调的单腿站立起立动作并进行运动想象时，皮层脊髓兴奋性会增强。	Valapil, A. C.	PDF	N/A	Corticospinal excitability is facilitated during coordinative action observation and motor imagery of adapted single-leg sit-to-stand movements in young healthy adults
利用大型语言模型自动化候选基因优先排序：基于API驱动的工作流程的开发与基准测试，借助GPT-4技术	khan, T.	PDF	N/A	Automating Candidate Gene Prioritization with Large Language Models: Development and Benchmarking of an API-Driven Workflow Leveraging GPT-4
亚胺培南/瑞来巴坦单独及联合使用对脓肿分枝杆菌囊性纤维化分离株的体外活性研究	Sanders, M.	PDF	N/A	In Vitro Activity of Imipenem/Relebactam Alone and in Combination Against Cystic Fibrosis Isolates of Mycobacterium abscessus
新生儿全身基因治疗在庞贝病大鼠模型中恢复了心肺功能	Fuller, D.	PDF	N/A	Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease
结合活体双光子成像与光激活荧光标记技术，揭示了骨骼肌中线粒体动力学的显著低速率。	O'Reilly, C. L.	PDF	N/A	Combining in vivo 2-photon imaging with photoactivatable fluorescent labeling reveals strikingly low rates of mitochondrial dynamics in skeletal muscle.
MatriCom：一种用于推断ECM-ECM和细胞-ECM通信系统的scRNA-Seq数据挖掘工具	Lamba, R.	PDF	N/A	MatriCom: a scRNA-Seq data mining tool to infer ECM-ECM and cell-ECM communication systems
μ-阿片受体激活增强了缰核-脚桥核突触的兴奋性传递。	Singhal, S. M.	PDF	N/A	Mu-opioid receptor activation potentiates excitatory transmission at the habenulo-peduncular synapse
经皮迷走神经刺激对噪音中语音识别的增强作用：一项交叉、安慰剂对照研究	Jigo, M.	PDF	N/A	Cervical transcutaneous vagus nerve stimulation enhances speech recognition in noise: A crossover, placebo-controlled study
体素级或区域级干扰回归在功能连接分析中的应用：有何区别？	Muganga, T.	PDF	N/A	Voxel-wise or Region-wise Nuisance Regression for Functional Connectivity Analyses: Does it matter?
由听觉剥夺引起的轴突起始段可塑性会降低对耳蜗植入神经反应模型中的时间差异敏感性。	Jing, A.	PDF	N/A	Axon initial segment plasticity caused by auditory deprivation degrades time difference sensitivity in a model of neural responses to cochlear implants
同时删除ZFP36L1和ZFP36L2基因可增强T细胞的细胞因子生成能力，但代价是细胞适应性下降。	Zandhuis, N.	PDF	N/A	Combined deletion of ZFP36L1 and ZFP36L2 drives superior cytokine production in T cells at the cost of cell fitness
一种新型的基于SARS-CoV-2衍生的传染性载体系统	Elfayres, G.	PDF	N/A	A novel SARS-CoV-2-derived infectious vector system
白斑综合症病毒早期蛋白（wsv100）通过拮抗NF-κB通路抑制虾的先天免疫反应	Xiao, B.	PDF	N/A	White Spot Syndrome Virus Immediate-Early Protein (wsv100) Antagonizes the NF-kappaB Pathway to Inhibit Innate Immune Response in shrimp
基于深度学习的病原性分枝杆菌化学积累预测	Sullivan, M. R.	PDF	N/A	Deep learning-based prediction of chemical accumulation in a pathogenic mycobacterium
将性二态性和左右不对称性整合到鸭鸣管的发育中	Mishkind, D.	PDF	N/A	Integration of sexual dimorphism and left-right asymmetry in the development of the duck syrinx
Sox15是一种新发现的视网膜发育基因，通过抑制替代性视杆光感受器命运来促进视锥光感受器的分化。	Belair-Hickey, J. J.	PDF	N/A	Sox15 is a novel retinal developmental gene that promotes cone photoreceptor differentiation through inhibition of alternative rod photoreceptor fates
巴西坎皮纳斯市与洪水相关的钩端螺旋体病病例：排水系统、不透水区域与社会脆弱性之间的相互作用	de Azevedo, T. S.	PDF	N/A	Flood-related cases of leptospirosis in Campinas, Brazil: the interplay between drainage, impermeable areas and social vulnerability
一种用于全球物种分布预测的生成式深度学习方法	YAN, Y.	PDF	N/A	A generative deep learning approach for global species distribution prediction
稻瘟病菌株中高度动态的额外小染色体	Lin, G.	PDF	N/A	Highly dynamic supernumerary mini-chromosomes in a Magnaporthe oryzae strain
利用机器学习提高对肺炎克雷伯菌抗菌药物耐药性的预测	Sevilla, J.	PDF	N/A	Improved prediction of antimicrobial resistance in Klebsiella pneumoniae using machine learning
姜黄精油局部应用可减轻丙酮诱导的Wistar白化大鼠特应性皮炎中的炎症标志物。	Musyoka, A. M.	PDF	N/A	Curcuma longa Essential Oil Topically Mitigates Inflammatory Markers in Acetone-Induced Atopic Dermatitis in Wistar Albino Rats
骨靶向肽选择用于治疗干预：体内评估与比较研究	Stellpflug, A.	PDF	N/A	Selection of Bone-Targeting Peptides for Therapeutic Intervention: An In Vivo Evaluation and Comparison Study
ConvMut：一种用于分析病毒系统发育中趋同突变的网络工具	Bernasconi, A.	PDF	N/A	ConvMut: A Web tool to analyze viral convergent mutations along phylogenies
用于对药物发现平台进行稳健、准确和可推广基准测试的策略	Van Norden, M.	PDF	N/A	Strategies for robust, accurate, and generalizable benchmarking of drug discovery platforms
患有长期新冠病毒的仓鼠在大脑干中表现出神经退行性特征。	Coleon, A.	PDF	N/A	Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
在ADAMTS13缺乏的情况下，微血栓的形成通过黏膜和内皮功能障碍加剧了溃疡性结肠炎。	Tatsuta, K.	PDF	N/A	Microthrombi-growth in ADAMTS13 deficiency exacerbated ulcerative colitis via mucosal and endothelial dysfunction
在肠道环境中，合成益生菌中用于消除目标基因的遗传安全措施	Nguyen, N.	PDF	N/A	A genetic safeguard for eliminating target genes in synthetic probiotics in a gut environment
酶CAGE：一种基于几何的酶检索基础模型，具有进化洞察力	Liu, Y.	PDF	N/A	EnzymeCAGE: A Geometric Foundation Model for Enzyme Retrieval with Evolutionary Insights
利用声遗传学-fPET技术，对基因和空间上有针对性地选择的神经群体进行无创调节，并映射其全球因果反应	Yang, Y.	PDF	N/A	Mapping Global Causal Responses to Noninvasive Modulation of Genetically and Spatially Targeted Neural Populations with Sonogenetic-fPET
有意延长与自发延长注视：基于主动注视交互的MEG研究	Vasilyev, A. N.	PDF	N/A	Intentionally vs. Spontaneously Prolonged Gaze: A MEG Study of Active Gaze-Based Interaction
NK细胞控制骨髓增生异常综合征的进展，但在NUP98-HOXD13小鼠模型中成为初始疾病靶点。	Telliam Dushime, G.	PDF	N/A	NK cells control the progression of myelodysplastic syndrome but become initial disease target in NUP98-HOXD13 mouse model
NLRP11在人巨噬细胞感染分枝杆菌期间，对于经典NLRP3和非经典炎症小体的激活是必需的。	Szczerba, M.	PDF	N/A	NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteria
一种bactofilin的亚域功能特化在Asticcacaulis biprosthecum中驱动柄状结构形态发生	Jacq, M.	PDF	N/A	Functional specialization of the subdomains of a bactofilin driving stalk morphogenesis in Asticcacaulis biprosthecum
对番茄潜叶蛾病毒组的特征分析揭示了田间种群中更高的病毒多样性	Becerra-Garcia, R. E.	PDF	N/A	Characterization of the Tuta absoluta virome reveals higher viral diversity in field populations
泛北极地区完整和退化多年冻土中的甲烷循环微生物群落	Wang, H.	PDF	N/A	The methane-cycling microbiome in intact and degraded permafrost soils of the pan-Arctic
多组学视角下黄曲霉对长链烷烃响应与聚乙烯降解的关系研究	Siaperas, R.	PDF	N/A	Multi-omics insights into the response of Aspergillus parasiticus to long-chain alkanes in relation to polyethylene degradation
Tax1bp1增强细菌的毒力，并在结核分枝杆菌感染肺泡巨噬细胞期间促进炎症反应。	Chin, J.	PDF	N/A	Tax1bp1 enhances bacterial virulence and promotes inflammatory responses during Mycobacterium tuberculosis infection of alveolar macrophages
Tunicate（被囊动物）的元转录组揭示了在致病病毒的进化历史中，古老的病毒-宿主共同分化以及目间重组的现象。	Petrone, M. E.	PDF	N/A	Tunicate metatranscriptomes reveal ancient virus-host co-divergence and inter-order recombination in the evolutionary history of disease-causing viruses
噬菌体Kil肽折叠成预测的螺旋-转角-螺旋结构，以破坏大肠杆菌细胞分裂。	Naha, A.	PDF	N/A	Bacteriophage Kil peptide folds into a predicted helix-turn-helix structure to disrupt Escherichia coli cell division
一种通过细胞外囊泡监测蛋白质转移的新方法	Pigden, O.	PDF	N/A	A New Approach to Monitoring Protein Transfer via Extracellular Vesicles
SARS-CoV-2中高度重复的多核苷酸突变	De Maio, N.	PDF	N/A	Highly recurrent multi-nucleotide mutations in SARS-CoV-2
从多种人类细胞类型中高效的无细胞翻译	Ziegelmueller, J.	PDF	N/A	Efficient cell-free translation from diverse human cell types
USP1/UAF1通过一种外切酶切机制，特异性地识别并作用于多聚泛素化的PCNA，从而富集单泛素化的PCNA。	Keijzer, N.	PDF	N/A	USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism that enriches for monoubiquitinated PCNA
使用GATE模拟前列腺癌患者来源的骨转移活检中的微米级阿尔法粒子剂量	Said, A.	PDF	N/A	Simulating Alpha Particle Doses at the Micron Scale from Prostate Cancer Patient Derived Bone Metastatic Biopsies Using GATE
基于人工智能的模型用于预测游离DNA样本中的克隆性造血突变	Arango-Argoty, G.	PDF	N/A	An artificial intelligence-based model for prediction of Clonal Hematopoiesis mutants in cell-free DNA samples
在白血病机器学习分类中使用保形预测减少错误	Lysenkova Wiklander, M.	PDF	N/A	Error reduction in leukemia machine learning classification with conformal prediction
使用抗HVEM阻断单克隆抗体治疗多种实体癌的新型免疫疗法	Galore-Haskel, G.	PDF	N/A	Novel immunotherapy for multiple solid cancers using an Anti-HVEM blocking monoclonal antibody
PARP抑制剂逆转了胶质母细胞瘤多形性对替莫唑胺的耐药性。	Samarut, E.	PDF	N/A	PARP inhibitor counteracts Temozolomide Resistance in Glioblastoma Multiforme
多重镶嵌肿瘤模型揭示了在群体内和群体间的药物反应中自然表型变异	Yu, J. X.	PDF	N/A	Multiplexed mosaic tumor models reveal natural phenotypic variations in drug response within and between populations
莱茵衣藻CLiP2突变体库通过高置信度的破坏性等位基因扩展了基因组覆盖范围。	Lunardon, A.	PDF	N/A	The Chlamydomonas reinhardtii CLiP2 mutant collection expands genome coverage with high-confidence disrupting alleles
细菌中用于RNA感应的条件性Degron标签	Simons, T. J.	PDF	N/A	A Conditional Degron Tag for RNA Sensing in Bacteria
为设计新型结合剂，绘制人类表面组上的可靶向位点	Balbi, P. E. M.	PDF	N/A	Mapping targetable sites on the human surfaceome for the design of novel binders
研究机械适应对空中超声振动触觉刺激的影响	Cataldo, A.	PDF	N/A	Investigating the effect of mechanical adaptation on mid-air ultrasound vibrotactile stimuli
氟西汀的青春期治疗会影响雌性青春期大鼠内侧前额叶皮层的成熟和行为	Kryst, J.	PDF	N/A	Juvenile fluoxetine treatment affects the maturation of the medial prefrontal cortex and behavior of adolescent female rats
有意义的记忆的随机树模型	Zhong, W.	PDF	N/A	Random Tree Model of Meaningful Memory
通过tRNS调节前刺激的阿尔法和贝塔节律功率，确立了它们在视觉感知中的因果作用。	Wei, J.	PDF	N/A	Modulating Prestimulus Alpha and Beta Power with tRNS Establishes Their Causal Role in Visual Perception
后内侧皮质中自然事件记忆再激活的核心神经状态集	Lee, Y.	PDF	N/A	A core set of neural states underlying memory reactivation of naturalistic events in the posterior medial cortex
T型钙通道参与了脊髓背角PKCγ神经元在慢性疼痛期间的内在和突触活动。	Cuculiere, C.	PDF	N/A	T-type calcium channels participate in intrinsic and synaptic activity of PKCγ neurons of the dorsal horn of the spinal cord during chronic pain
巨细胞病毒和类风湿性关节炎对衰老的CD4+ T细胞具有不同的影响	Williams, L.	PDF	N/A	Divergent effects of cytomegalovirus and rheumatoid arthritis on senescent CD4+ T cells
在乌苏图病毒脑炎期间，CCR2在单核细胞招募和血脑屏障破坏中起着核心作用。	Slowikowski, E.	PDF	N/A	A central role for CCR2 in monocyte recruitment and blood-brain barrier disruption during Usutu virus encephalitis
尽管糖基转移酶表达相同，IgA在位点和亚类上仍表现出特定的糖型差异。	Falck, D.	PDF	N/A	IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression
海藻糖二霉菌酸酯通过非经典SNARE相互作用抑制吞噬体成熟并促进胞内结核分枝杆菌生长。	Santamaria, C.	PDF	N/A	Trehalose dimycolate inhibits phagosome maturation and promotes intracellular M. tuberculosis growth via noncanonical SNARE interaction
使用ARTiMiS流式成像显微技术对营养回收过程中微藻群落的形态型进行解析	Gincley, B.	PDF	N/A	Morphotype-Resolved Characterization of Microalgal Communities in a Nutrient Recovery Process with ARTiMiS Flow Imaging Microscopy
2016年至2022年荷兰乌苏图病毒和西尼罗病毒的出现与动态	Munger, E.	PDF	N/A	Emergence and Dynamics of Usutu and West Nile Viruses in the Netherlands, 2016-2022
DIYNAFLUOR：一种经济实惠的即插即用型核酸荧光计，适用于资源有限环境中的环境DNA定量分析	Anderson, W.	PDF	N/A	DIYNAFLUOR: An Affordable DIY Plug-and-Play Nucleic Acid Fluorometer for eDNA Quantification in Resource Limited Settings
人类RNase H2的上调能够对抗癌基因和化疗引起的复制压力。	Wilkins, R. J.	PDF	N/A	Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress
细胞连接mRNA的本地化翻译对于上皮细胞极性是必需的。	Chin, A.	PDF	N/A	Localized translation of cell junction mRNAs is required for epithelial cell polarity
Maf1与孕酮受体合作，共同抑制RNA聚合酶III对特定tRNA的转录。	Finlay-Schultz, J.	PDF	N/A	Maf1 Cooperates with Progesterone Receptor to Repress RNA Polymerase III Transcription of Select tRNAs
入侵的仙人掌（Opuntia cacti）对哺乳动物栖息地使用的影响对比	Stewart, P. S.	PDF	N/A	Contrasting impacts of invasive Opuntia cacti on mammal habitat use
田野蟋蟀中武器和攻击行为的进化	Judge, K. A.	PDF	N/A	The evolution of weaponry and aggressive behaviour in field crickets
生态资源竞争作为金属组进化的一种驱动力	Sobol, M.	PDF	N/A	Ecological resource competition as a driver of metallome evolution
超越大陆群体的人类遗传变异的多尺度复杂性	Palma-Martinez, M. J.	PDF	N/A	The multi-scale complexity of human genetic variation beyond continental groups
通过衰老在果蝇头部基因表达的动态变化	Macdonald, S. J.	PDF	N/A	Dynamic Changes in Gene Expression Through Aging in Drosophila melanogaster Heads
传感器融合算法用于提高使用六自由度位置传感器进行机器人叠加测试的精度	Gillespie, C. M.	PDF	N/A	Sensor Fusion Algorithm to Improve Accuracy of Robotic Superposition Testing using 6-DOF Position Sensors
FeatureForest：结合基础模型的强大功能与随机森林的易用性	Seifi, M.	PDF	N/A	FeatureForest: the power of foundation models, theusability of random forests
机器学习预测超越单个mRNA作为单细胞蛋白质表达的代理	Fisher, J.	PDF	N/A	Machine Learning Predictions Surpass Individual mRNAs as a Proxy of Single-cell Protein Expression
Prosit-XL：通过精确的片段强度预测增强交联肽鉴定，用于研究蛋白质-蛋白质相互作用和蛋白质结构	Kalhor, M.	PDF	N/A	Prosit-XL: enhanced cross-linked peptide identification by accurate fragment intensity prediction to study protein-protein interactions and protein structures
一个专注于精准肿瘤学的深度学习框架，用于个性化选择癌症治疗方案	Sederman, C.	PDF	N/A	A precision oncology-focused deep learning framework for personalized selection of cancer therapy
SL/Kh 前B细胞淋巴瘤起源于胸腺，是原发性纵隔（胸腺）大B细胞淋巴瘤的一个模型。	Thomae, T. L.	PDF	N/A	SL/Kh Pre-B Lymphomas Originate in the Thymus and are a Model for Primary Mediastinal (Thymic) Large B-Cell Lymphoma
敲入Kcnh2的长QT综合征2型、癫痫和猝死兔模型	Singh, V.	PDF	N/A	Knock-in Kcnh2 Rabbit Model of Long QT Syndrome Type-2, Epilepsy, and Sudden Death
通过基因沉默KCa3.1可抑制ApoE基因敲除小鼠的动脉粥样硬化。	Alam, P.	PDF	N/A	Genetic silencing of KCa3.1 inhibits atherosclerosis in ApoE null mice
高产环境下油菜籽灌浆期耐热性的研究	Verdejo, J. F.	PDF	N/A	Resilience of rapeseed to heat stress during grain filling in a high yielding environment
基因组尺度模型中噬菌体代谢劫持的协同与拮抗作用	Rozum, J. C.	PDF	N/A	Synergy and antagonism in a genome-scale model of metabolic hijacking by bacteriophage
在奖励最大化过程中位置场重组的模型	Kumar, M. G.	PDF	N/A	A Model of Place Field Reorganization During Reward Maximization
皮层状态变化通过听觉异常：无意识中的失配反应生成机制	Hockley, A.	PDF	N/A	Cortical state change by auditory deviants: a mismatch response generation mechanism in unconsciousness
惩罚性时间判断增强了代理感，并调节了其潜在的神经相关因素。	Hill, C.	PDF	N/A	Punishing temporal judgement boosts sense of agency and modulates its underlying neural correlates
前额叶皮层多巴胺对刺激的总效价产生反应。	Yang, Y.	PDF	N/A	Prefrontal cortex dopamine responds to the total valence of stimuli
蛋白质组传感器用于定量、多重和空间监测激酶信号传导	Comstock, W. J.	PDF	N/A	Proteomic Sensors for Quantitative, Multiplexed and Spatial Monitoring of Kinase Signaling
鉴定出对逆转录转座必需的最小Alu域	Moldovan, J. B.	PDF	N/A	Identification of a minimal Alu domain required for retrotransposition
利用培养边界条件调控肾脏发育轨迹	Huang, A. Z.	PDF	N/A	Engineering kidney developmental trajectory using culture boundary conditions
羽毛图标：鸟类物种吸引全球关注的驱动力	Si, H.	PDF	N/A	Feathered Icons: Drivers of Global Attention on Bird Species
未来的气候和土地利用变化将同样影响全球陆地脊椎动物的多样性。	Hari, C.	PDF	N/A	Future climate and land use change will equally impact global terrestrial vertebrate diversity
发送混合信号：亚马逊蝴蝶同域姐妹物种中的趋同虹彩和趋异化学信号	Ledamoisel, J.	PDF	N/A	Sending mixed signals: convergent iridescence and divergent chemical signals in sympatric sister-species of Amazonian butterflies
递归剪接去除内含子是否是基因组巨型化演化的必要条件？	Adams, A. N.	PDF	N/A	Is intron removal by recursive splicing necessitated by the evolution of genomic gigantism?
具有性二态尾羽的燕子具有更高的物种形成速率。	Hasegawa, M.	PDF	N/A	Swallows with sexually dimorphic tails have higher speciation rates
结构重排和选择促进安乐蜥蜴的表型进化	Araya Donoso, R.	PDF	N/A	Structural rearrangements and selection promote phenotypic evolution in Anolis lizards
从单核ATAC-seq获得的高分辨率减数分裂交叉图揭示了哺乳动物精子中重组景观的见解	Crismani, W.	PDF	N/A	A high-resolution meiotic crossover map from single-nucleus ATAC-seq reveals insights into the recombination landscape in mammalian sperm
组织特异性表观线粒体DNA异质性及其与衰老和线粒体DNA基因表达的关系	Wengert, S.	PDF	N/A	Tissue-specific apparent mtDNA heteroplasmy and its relationship with ageing and mtDNA gene expression
携带超大负荷可能会在切叶蚁中产生信息素“盲点”。	Porras-Brenes, K.	PDF	N/A	Carrying oversized loads may create pheromone 'blind spots' in leafcutter ants.
利用四向相位编码优势实现EPI伪影的鲁棒检测与校正：应用于扩散MRI中的残余鬼影	Thai, A.	PDF	N/A	Exploiting Four-way Phase-encoding Benefits for Robust Detection and Correction of EPI artifacts: Application to Residual Ghosts in Diffusion MRI.
以人工智能为核心的致病蛋白质靶点结构识别	Saluri, M.	PDF	N/A	AI-first structural identification of pathogenic protein targets
基于领域自适应蛋白质语言模型和可解释几何深度学习的精确核酸结合残基识别	Zeng, W.	PDF	N/A	Accurate nucleic acid-binding residue identification based on domain-adaptive protein language model and explainable geometric deep learning
食物质量和vgll3基因型影响大西洋雌性鲑鱼的繁殖特征。	Maamela, K. S.	PDF	N/A	Food quality and vgll3 genotype influence reproductive traits in female Atlantic salmon
微生物功能群和基因是解释土壤养分循环的关键，与土壤和植物变量同样重要。	Vietorisz, C. R.	PDF	N/A	Microbial functional guilds and genes are key to explaining soil nutrient cycling alongside soil and plant variables
恢复阿尔茨海默病中的振荡动力学：一种关于血清素类迷幻药物作用的分层全脑模型	Gendra, J. C.	PDF	N/A	Restoring Oscillatory Dynamics in Alzheimer's Disease: A Laminar Whole-Brain Model of Serotonergic Psychedelic Effects
Foxg1及其伙伴们：不仅仅是转录因子	Mallamaci, A.	PDF	N/A	Foxg1 and companions: not only transcription factors
邻里剥夺、遗传易感性与生活满意度：来自德国双生子家庭面板的证据	Harerimana, N. V.	PDF	N/A	Neighborhood Deprivation, Genetic Predisposition, and Life Satisfaction: Evidence from the German Twin Family Panel
# BioRxiv 2024-12-15 Papers

标题	作者	PDF链接	代码仓库	Title
默认模式网络连接性预测个体在长期遗忘中的差异：存储衰减的证据，而非提取失败	Xu, Y.	PDF	N/A	Default Mode Network Connectivity Predicts Individual Differences in Long-Term Forgetting: Evidence for Storage Decay, not Retrieval Failure
光环：单细胞多组学数据的层次因果建模	Mao, H.	PDF	N/A	HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data
糖原贮积症1a型中与疾病相关的细胞记忆编程	Sprecher, U.	PDF	N/A	Disease-associated programming of cell memory in glycogen storage disorder type 1a
植物基因组的高效组装：以毛茛属（毛茛科）为例，探讨其进化意义	Karbstein, K.	PDF	N/A	Efficient assembly of plant genomes: A case study with evolutionary implications in Ranunculus (Ranunculaceae)
蛋白质语言模型监督的可扩展方法，用于多样化和可设计的蛋白质基序-支架结构，基于GPDL	Zhang, B.	PDF	N/A	Protein Language Model Supervised Scalable Approach for Diverse and Designable Protein Motif-Scaffolding with GPDL
MIOSTONE：利用自适应分类神经网络建立微生物组与性状的关联模型	Jiang, Y.	PDF	N/A	MIOSTONE: Modeling microbiome-trait associations withtaxonomy-adaptive neural networks
探索转折（ExploreTurns）：一种用于探索、分析和分类蛋白质中beta转折和结构化环的网络工具；应用于beta凸起和Schellman环、Asx螺旋帽、beta发夹以及其他氢键连接的基序。	Newell, N. E.	PDF	N/A	ExploreTurns: A web tool for the exploration, analysis, and classification of beta turns and structured loops in proteins; application to beta-bulge and Schellman loops, Asx helix caps, beta hairpins and other hydrogen-bonded motifs
通过碱基编辑修复番茄花调控基因中的有害驯化变异	Glaus, A. N.	PDF	N/A	Repairing a deleterious domestication variant in a floral regulator gene of tomato by base editing
一种自我关注偏向的神经特征	Geisler, D. J.	PDF	N/A	A Neural Signature of the Bias Towards Self-Focus
MicroRNA-26b 在保护小鼠免受MASH（代谢相关脂肪性肝炎）发展方面具有作用，并且可以通过脂质纳米颗粒进行有效靶向。	Peters, L.	PDF	N/A	MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles.
在不同黄鲈（Perca flavescens）种群中，有效群体大小变化背景下并行的遗传适应	Yin, X.	PDF	N/A	Parallel genetic adaptation amidst a background of changing effective population sizes in divergent yellow perch (Perca flavescens) populations
更强的蝙蝠捕食压力和较弱的环境限制预示着蛾子尾巴更长。	Rubin, J.	PDF	N/A	Stronger bat predation and weaker environmental constraints predict longer moth tails
一种长寿命、跨大陆迁徙鸟类的扩散、成熟和繁殖	Mirski, P.	PDF	N/A	Dispersal, maturation and recruitment in a long-lived, trans-continentally migrating bird
一种VLP疫苗平台，包含乙型肝炎病毒的核心蛋白与N端抗原捕获。	Fatema, K.	PDF	N/A	A VLP vaccine platform comprising the core protein of hepatitis B virus with N-terminal antigen capture
细胞周期振荡器和纺锤体长度决定了果蝇胚胎中染色体分离的速度。	Xu, Y.	PDF	N/A	The cell cycle oscillator and spindle length set the speed of chromosome separation in Drosophila embryos
通过小脑和基底神经节的协同合作实现协同强化学习	Yohida, T.	PDF	N/A	Synergistic reinforcement learning by cooperation of the cerebellum and basal ganglia
PhyloMix：通过系统发育混合增强技术提升微生物组-性状关联预测	Jiang, Y.	PDF	N/A	PhyloMix: Enhancing microbiome-trait association prediction through phylogeny-mixing augmentation
弱监督向量量化在全切片图像分类中的应用	Shen, D.	PDF	N/A	Weakly Supervised Vector Quantization for Whole Slide Image Classification
慈鲷鱼面部表情的社会效益：检验面部集中假设	Satoh, S.	PDF	N/A	Social benefits of facial experssion in a cichlid fish: Testing the face concentration hypothesis
顶端网格蛋白包被的凹陷控制微绒毛生长的位置、时间及规模。	Perkins, O. L.	PDF	N/A	Apical clathrin-coated pits control the location, timing, and scale of microvillar growth
情境依赖的NMDA受体功能障碍预测携带人GluN1变异的小鼠的癫痫治疗效果	Venkatesan, S.	PDF	N/A	Context-dependent NMDA receptor dysfunction predicts seizure treatment in mice with human GluN1 variant
量化生物模式形成的复杂性：通过复杂性度量的新视角	Riedel, J. H. R.	PDF	N/A	Quantifying the intricacies of biological pattern formation: A new perspective through complexity measures
全息层析显微镜揭示了在血管内皮化过程中，内皮细胞的无标记定量动态变化。	Leineweber, W. D.	PDF	N/A	Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization
人类疾病机制的基础模型在罕见病和常见病中的表示学习	Ravandi, B.	PDF	N/A	Representation Learning of Human Disease Mechanisms for a Foundation Model in Rare and Common Diseases
一氧化氮通过S-亚硝基化调节Rab5的吞噬作用	Hagiwara, M.	PDF	N/A	Nitric oxide regulates phagocytosis through S-nitrosylation of Rab5
用于晶体衍射数据质量评估的I/σI与{Rmerg, Rmeas, Rpim, CC1/2}关系图	Fu, Z.	PDF	N/A	I/σI vs {Rmerg, Rmeas, Rpim, CC1/2} for Crystal Diffraction Data Quality Evaluation
特定磷酸化模式在Tau-R4寡聚化中的作用	Bressler, S. G.	PDF	N/A	The role of specific phosphorylation patterns in the oligomerization of Tau-R4
野生东部黑猩猩在呼叫声中的性别差异	Holden, E.	PDF	N/A	Sex differences in pant-hoot vocalizations in wild Eastern chimpanzees
在老鼠的社会信任任务中，催产素增强了获取能力，而催产素及其拮抗剂则阻止了信任违背的学习。	Budniok, S.	PDF	N/A	Oxytocin enhances acquisition in a social trust task in mice, whereas both oxytocin and its antagonist block trust violation learning
剖析密集皮层连接组中连线特异性的起源	Harth, P.	PDF	N/A	Dissecting origins of wiring specificity in dense cortical connectomes
rx3基因促进了墨西哥洞穴鱼（Astyanax mexicanus）眼睛退化的演化。	Shennard, D.	PDF	N/A	The rx3 gene contributes to the evolution of eye loss in the cavefish Astyanax mexicanus
在PDB结构模型中对结合位点的偏倚建模	Wankowicz, S. A.	PDF	N/A	Modeling Bias Toward Binding Sites in PDB Structural Models
在小鼠中，情节性缓慢呼吸显著减少了恐惧反应。	de Sousa Abreu, R. P.	PDF	N/A	Episodic slow breathing in mice markedly reduces fear responses
记忆和压力对选择一致性的影响	Xin, F.	PDF	N/A	The Impact of Memory and Stress on Choice Consistency
在坐骨神经再生过程中对大鼠进行比目鱼肌H反射上调训练可改善其运动功能的恢复	Chen, Y.	PDF	N/A	Soleus H-Reflex Up-Conditioning during Sciatic Nerve Regeneration in Rats Improves Recovery of Locomotion
大鼠、小鼠和人类在时间投资方面的有限最优性	Ott, T.	PDF	N/A	Bounded optimality of time investments in rats, mice, and humans
利用图像分析技术对氧化石墨烯纳米颗粒的微生物还原进行稳健测量	Bennett, D. T.	PDF	N/A	Robust measurement of microbial reduction of graphene oxide nanoparticles using image analysis
使用信号时序逻辑学习生物分子模型	Krasowski, H.	PDF	N/A	Learning Biomolecular Models using Signal Temporal Logic
TGFβ1与RGD协同调控SMAD 2/3介导的前列腺癌细胞在生物正交构建的水凝胶中的促癌效应	Pol, M.	PDF	N/A	TGFβ1 and RGD Cooperatively Regulate SMAD 2/3 Mediated Oncogenic Effects in Prostate Cancer Cells in Bioorthogonally Constructed Hydrogels
疾病对肾血流调节的影响：评估自调节紊乱	Maddineni, B.	PDF	N/A	Effects of Disease on Renal Blood Flow Regulation: Assessing Autoregulation Disruption
皮层介导的肌肉对平衡干扰的反应在有和没有帕金森病的老年人中，随着干扰强度的增加而增强。	Boebinger, S. E.	PDF	N/A	Cortically-mediated muscle responses to balance perturbations increase with perturbation magnitude in older adults with and without Parkinson's disease
在鸟类学交汇处的鸣禽DNA条形码分析揭示了显著的东西向遗传谱系分化	Tehrani, S. J.	PDF	N/A	DNA barcoding of passerine birds at an ornithological crossroad reveals significant East-West genetic lineage divergence
草原旱獭（Marmota bobak Muller, 1776）的谱系地理学与遗传结构	Brandler, O. V.	PDF	N/A	Phylogeography and genetic structure of the steppe marmot (Marmota bobak Muller, 1776)
淡水虾（Macrobrachium Spp.）肠道中产酶微生物的特性与鉴定	nimbalkar, d. n.	PDF	N/A	Characterization and identification of enzyme-producing microflora isolated from the gut of freshwater Prawn, Macrobrachium Spp
暴露于低剂量壶菌（Batrachochytrium dendrobatidis）下的研究表明，极度濒危的南部corroboree蛙在抗性方面存在差异。	Davidson, M. J.	PDF	N/A	Exposure to low doses of Batrachochytrium dendrobatidis reveals variation in resistance in the Critically Endangered southern corroboree frog
体外研究Tropilaelaps mercedesae在多种基质上的存活情况。	Gill, M. C.	PDF	N/A	An in vitro investigation into the survival of Tropilaelaps mercedesae on a range of matrices.
在一个严格厌氧的产甲烷菌群中识别出一组苯激活酶	Toth, C. R. A.	PDF	N/A	Identification of a Cluster of Benzene Activation Enzymes in a Strictly Anoxic Methanogenic Consortium
2018年至2019年间在菲律宾水域搁浅的鲸类动物中分离出的肠杆菌科细菌的抗性谱和基因，为揭示海洋环境中抗菌药物抗性的程度提供了线索。	Obusan, M. C.	PDF	N/A	Resistance profiles and genes of Enterobacteriaceae from cetaceans stranded in Philippine waters from 2018-2019 provide clues on the extent of antimicrobial resistance in the marine environment
MEGA12：分子进化遗传分析适应性与绿色计算版本12	Kumar, S.	PDF	N/A	MEGA12: Molecular Evolutionary Genetic Analysis version 12 for adaptive and green computing
结构上不同的锰感应核糖开关适体调控多种表达平台架构	Mishanina, T.	PDF	N/A	Structurally distinct manganese-sensing riboswitch aptamers regulate diverse expression platform architectures
十八烷类作为珊瑚-腰鞭虫共生中的新兴脂质介质	Botana, M. T.	PDF	N/A	Octadecanoids as emerging lipid mediators in cnidarian-dinoflagellate symbiosis
短RNA分子伴侣促进TDP-43蛋白形成抗聚集的构象，从而减轻神经退行性病变。	Copley, K. E.	PDF	N/A	Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
通过代谢工程改造的Komagataella phaffii经紫外线诱变提高甲醇生产D-乳酸的效率	Inoue, Y.	PDF	N/A	Improvement of D-lactic acid production from methanol by metabolically engineered Komagataella phaffii via ultra-violet mutagenesis
利用靶向增强超声成像量化子痫前期大鼠胎盘中分子变化	Shi, L.	PDF	N/A	Quantifying Molecular Changes in the Preeclamptic Rat Placenta with Targeted Contrast-Enhanced Ultrasound Imaging
APHIX：使用长读长RNA测序数据进行HIV-1异构体探索的分析管道	Albert, J. L.	PDF	N/A	APHIX: Analysis Pipeline for HIV-1 Isoform eXploration Using Long-read RNA Sequencing Data
用于器官特异性年龄和慢性疾病预测的紧凑型蛋白质组	Vladimirova, A.	PDF	N/A	A compact protein panel for organ-specific age and chronic disease prediction
人类钙化主动脉瓣狭窄发病机制中的血浆和组织蛋白质组的性别二态性	Clift, C. L.	PDF	N/A	Sexual Dimorphism of Plasma and Tissue Proteomes in Human Calcific Aortic Valve Stenosis Pathogenesis
与人类大腿和小腿肌肉转录组在基础状态和废用一周后调控相关的转录因子	Borzykh, A.	PDF	N/A	Transcription factors associated with regulation of transcriptome in human thigh and calf muscles at baseline and after one week of disuse
刺激内侧黑质网状部促进持续运动恢复并对抗多巴胺耗竭小鼠的帕金森病病理生理学	Aristieta, A.	PDF	N/A	Stimulation of the Medial SNr Promotes Sustained Motor Recovery and Counteracts Parkinsonian Pathophysiology in Dopamine Depleted Mice
通过自动微分优化脑微结构成像的实验设计	Farooq, H.	PDF	N/A	Experimental Design Optimization for Brain Microstructure Imaging via Automatic Differentiation
4-苯基丁酸通过调节连接蛋白43的表达，限制了鼠β冠状病毒的感染性和病毒引起的脱髓鞘作用。	Kasle, G.	PDF	N/A	4-Phenylbutyric acid modulates Connexin 43 expression restricting murine-β-coronavirus infectivity and virus-induced demyelination
成本效益决策的计算原语	Rakocevic, L. I.	PDF	N/A	Computational Primitives for Cost-Benefit Decision-Making
在迷幻状态期间，背外侧前额叶皮层在自我消解和情绪唤起中的作用	Coleman, C. R.	PDF	N/A	The Role of the Dorsolateral Prefrontal Cortex in Ego Dissolution and Emotional Arousal During the Psychedelic State
从胸腺中出现的记忆表型Ly49+ CD8 T细胞分化为两个具有不同免疫功能的亚群。	Laubreton, D.	PDF	N/A	Memory-Phenotype Ly49+ CD8 T emerging from the thymus develop into two subsets with distinct immune functions
益生菌补充对鲤鱼水体和肠道微生物群的影响	Jakimowicz, M.	PDF	N/A	The impact of probiotic supplementation with effective microorganisms on water and gut microbiome of the Common carp
临床试验化合物NITD-688抑制登革病毒的机制性见解	Wang, Y.	PDF	N/A	Mechanistic Insights into Dengue Virus Inhibition by a Clinical Trial Compound NITD-688
酵母（Saccharomyces cerevisiae）线粒体AMPylome的分析揭示了通过δ亚基调控ATP合酶偶联的机制。	Kucharczyk, R.	PDF	N/A	Profiling of yeast Saccharomyces cerevisiae mitochondrial AMPylome reveals a regulation of ATP synthase coupling trough subunit delta
鉴定与成人一生中背外侧前额叶皮层衰老相关的环状RNA	Amjadi-Moheb, F.	PDF	N/A	Identification of Circular RNAs associated with Ageing of the Dorsolateral Prefrontal Cortex across the Adult Lifespan
通过可解释的人工智能分析飞行轨迹，区分易感和抗性冈比亚按蚊的固有特征	Qureshi, Y.	PDF	N/A	Discrimination of inherent characteristics of susceptible and resistant strains of Anopheles gambiae by explainable Artificial Intelligence Analysis of Flight Trajectories
基于激活的高通量筛选识别出caspase-10抑制剂	Castellon, J. O.	PDF	N/A	An activation-based high throughput screen identifies caspase-10 inhibitors
石墨烯-聚合物纳米纤维实现光诱导的干细胞衍生心肌细胞和脑类器官的电成熟	LaMontagne, E.	PDF	N/A	Graphene-polymer Nanofibers Enable Optically Induced Electrical Maturation in Stem Cell-Derived Cardiomyocytes and Brain Organoids
ProCyon：一种用于蛋白质表型的多模态基础模型	Queen, O.	PDF	N/A	ProCyon: A multimodal foundation model for protein phenotypes
单细胞RNA测序数据中，全面的工作流程用于等位基因特异性免疫基因定量和表达分析	Al Ajami, A.	PDF	N/A	A comprehensive workflow for allele-specific immune gene quantification and expression analysis in single-cell RNA-seq data
主导的RDH12-视网膜色素变性损害视网膜类器官中的光感受器发育和锥体功能	Mejecase, C.	PDF	N/A	Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and cone function in retinal organoids
利用高通量表型分析技术研究高粱CRISPR-Cas9突变体的氮素响应及生长轨迹	Jin, H.	PDF	N/A	Nitrogen response and growth trajectory of sorghum CRISPR-Cas9 mutants using high-throughput phenotyping
一个关于东部马脑炎病毒在易感宿主细胞中复制的详细动力学模型	Larkin, C. I.	PDF	N/A	A detailed kinetic model of Eastern equine encephalitis virus replication in a susceptible host cell
旅行波增强了人类情景记忆和工作记忆中的海马-旁海马耦合	Chen, X.	PDF	N/A	Traveling waves enhance hippocampal-parahippocampal couplings in humanepisodic and working memory
探索GBA1宿主基因型与GBA1L444P/WT小鼠模型肠道微生物群之间的关系：对帕金森病发病机制的启示	Menozzi, E.	PDF	N/A	Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1L444P/WT mouse model: Implications for Parkinson disease pathogenesis
人类成年肌肉型烟碱受体在静息状态和脱敏状态下的结构	Li, A.	PDF	N/A	Structures of the human adult muscle-type nicotinic receptor in resting and desensitised states
使用脂质捕获质谱法识别分裂细胞中特定的脂质-蛋白质相互作用	Paquola, A.	PDF	N/A	Identification of specific lipid-protein interactions in dividing cells using lipid-trap mass spectrometry
双编码基因SLC35A4具有抗氧化应激的保护作用。	Ajala, I.	PDF	N/A	The dual coding gene SLC35A4 protects against oxidative stress
NOTCH1 S2513对于调控源自hiPSC的PSM细胞和体节体中NICD水平至关重要，影响着分节钟的运作。	Meijer, H. A.	PDF	N/A	NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids
作为无害的乘客：寄生在埋葬甲虫Nicrophorus nepalensis身上的捕食性螨对择偶无影响	Lan, B.	PDF	N/A	Phoretic mites as benign passengers: no influence on mate choice in the burying beetle Nicrophorus nepalensis
demres：一个用于研究时间变化人口复原力的R包	Louvrier, J.	PDF	N/A	demres: An R package to study time-varying demographic resilience
两个不同的单倍体核塑造了小麦条锈病种群多样性的格局。	Wang, Y.	PDF	N/A	Two divergent haploid nuclei shaped the landscape of population diversity in wheat stripe rust
gaftools：一个用于分析和操作泛基因组比对工具包	Pani, S.	PDF	N/A	gaftools: a toolkit for analyzing and manipulating pangenome alignments
cancerSimCraft：一种具有全面基础真值追踪的多分辨率癌症基因组模拟器	Jin, H.	PDF	N/A	cancerSimCraft: A Multi-resolution Cancer Genome Simulator with Comprehensive Ground Truth Tracking
整合转录组学、代谢组学和脂质组学分析揭示了调节性T细胞激活后的独特脂质特征	Sato, Y.	PDF	N/A	Integrated transcriptomic, metabolomic, and lipidomic analyses reveal a unique lipid profile of regulatory T cells upon activation
一种从多潜能脑血管壁龛中分离血脑屏障和窗孔血管的分子机制	Lee, N. J.	PDF	N/A	A molecular mechanism for blood-brain barrier and fenestrated vessel segregation from a multipotent cerebrovascular niche
雌二醇对大鼠认知衰老的益处与其对心血管代谢健康的影响无关。	Montanari, C.	PDF	N/A	The benefits of estradiol on cognitive aging in rats are independent from its effects on cardiometabolic health
多反应性水凝胶纳米小瓶用于抗体分泌细胞分泌捕获的时间控制	Mellody, M. P.	PDF	N/A	Multi-reactive hydrogel nanovials for temporal control of secretion capture from antibody-secreting cells
8纳米长的“意大利面”：从淡水中发现的，由冷冻技术揭示的，结构良好的糖类包裹的线性四肽重复序列。	Wang, T.	PDF	N/A	The 8-nm spaghetti: well-structured glycans coating linear tetrapeptide repeats discovered from freshwater with CryoSeek
靶向KRAS(G12V)降解在体内有效且持久地诱导肺腺癌消退	Martin, A.	PDF	N/A	Targeted KRAS(G12V) degradation elicits efficient and durable lung adenocarcinoma regression in vivo
使用OPM-MEG测量的听觉MMN的重测信度	Demko, L.	PDF	N/A	Test-retest reliability of auditory MMN measured with OPM-MEG
在原始后生动物胚胎中，功能性神经回路的组装受到环境信号的影响，包括微生物群。	Noack, C.	PDF	N/A	Assembly of a functional neuronal circuit in embryos of an ancestral metazoan is influenced by environmental signals including the microbiome
一个简单的神经回路模型解释了知觉决策中多种类型的整合核	Shen, X.	PDF	N/A	A simple neural circuit model explains diverse types of integration kernels in perceptual decision-making
在疾病预测模型中使用抗体结构信息揭示了大量免疫组库数据中的抗原特异性B细胞受体序列	Nwogu, O.	PDF	N/A	Use of Antibody Structural Information in Disease Prediction Models Reveals Antigen Specific B Cell Receptor Sequences in Bulk Repertoire Data
巨噬细胞迁移依赖的收缩纤维与迁移体——细胞因子时空分泌的结构基础。	Li, X.	PDF	N/A	Macrophage migration-dependent retraction fibers and migrasomes - a structural basis for spatiotemporal cytokine secretion.
栖息地质量通过皮质醇影响西伯利亚鼯鼠（Pteromys volans）的肠道微生物群。	Petrullo, L.	PDF	N/A	Habitat quality influences gut microbiota via cortisol in Siberian flying squirrels (Pteromys volans)
一个关于刀耕火种农业中劳动互惠和规范推理的复杂适应系统模型	Tverskoi, D.	PDF	N/A	A complex adaptive systems model of labor reciprocity and normative reasoning in swidden agriculture
在鸟类（Vangidae）适应性辐射过程中，多个性状的进化速度和模式	Auerbach, A. L. B.	PDF	N/A	Tempo and mode of evolution across multiple traits in an adaptive radiation of birds (Vangidae)
从ELOV2基因组区域评估DNA甲基化足以预测生理年龄。	Zhu, B.	PDF	N/A	Assessment of DNA methylation from a single genomic region of ELOV2 is sufficient to predict chronological age
基因组分化塑造了芸苔属异源多倍体减数分裂同源重组的遗传调控	PELE, A.	PDF	N/A	Genomic divergence shaped the genetic regulation of meiotic homologous recombination in Brassica allopolyploids
关于绒螯蟹属杂交与物种形成的基因组见解	Wang, C.	PDF	N/A	Genomic Insights into Hybridization and Speciation of Mitten Crabs in the Eriocheir Genus
使用表面肌电图评估手动任务中的前臂用力：通过前臂与肌肉特定肌电图放置方式的比较分析	Fan, X.	PDF	N/A	Assessing Forearm Exertion in Manual Tasks with Surface EMG: A Comparative Analysis of Through-Forearm vs. Muscle Specific EMG Placements
scSurv：一种用于单细胞生存分析的深度生成模型	Mizukoshi, C.	PDF	N/A	scSurv: a deep generative model for single-cell survival analysis
环境盐度对鲑科鱼类独特神经内分泌复合体的调控	Culbert, B. M.	PDF	N/A	Regulation of a unique neuroendocrine complex by environmental salinity in salmonid fishes
近亲繁殖和人口动态相互作用，影响种群从瓶颈效应中的恢复。	Zheng, J.	PDF	N/A	Inbreeding and demography interact to impact population recovery from bottlenecks
能量转换预测冈比亚按蚊的死亡率	Zeferino, T. G.	PDF	N/A	Energetic shifts predict the mortality of Anopheles gambiae
# BioRxiv 2024-12-14 Papers

标题	作者	PDF链接	代码仓库	Title
数学和生物学上一致的存在-缺失成对指数框架	Sizling, A. L.	PDF	N/A	Mathematically and biologically consistent framework for presence-absence pairwise indices
非经典端粒酶逆转录酶通过STAT5调控主动脉瓣细胞的成骨性重编程	Cuevas, R. A.	PDF	N/A	Non-canonical Telomerase Reverse Transcriptase Controls Osteogenic Reprogramming of Aortic Valve Cells Through STAT5
Stu2在动粒中具有一个独立于调节微管动力学的重要功能。	Abouelghar, A. A.	PDF	N/A	Stu2 has an essential kinetochore role independent of regulating microtubule dynamics
Hermansky-Pudlak综合征中失调的肺泡上皮细胞祖细胞功能与特性	Wang, J. Y.	PDF	N/A	Dysregulated alveolar epithelial cell progenitor function and identity in Hermansky-Pudlak syndrome
蜜月阴暗面：通过基因组学视角重构亚洲与欧洲玫瑰育种历史	Leroy, T.	PDF	N/A	Dark side of the honeymoon: reconstructing the Asian x European rose breeding history through the lens of genomics
个体幸福感差异得到了一系列可分离的、与自我注意和视觉注意相关的脑网络的支持。	Ma, Y.	PDF	N/A	Individual differences in wellbeing are supported by separable sets of co-active self- and visual-attention-related brain networks
IgDesign：利用反向折叠技术针对多种治疗性抗原进行体外验证的抗体设计	Shanehsazzadeh, A.	PDF	N/A	IgDesign: In vitro validated antibody design against multiple therapeutic antigens using inverse folding
使用由分支概率参数化的树分布进行精确的贝叶斯系统发育点估计	Berling, L.	PDF	N/A	Accurate Bayesian phylogenetic point estimation using a tree distribution parameterized by clade probabilities
三部分ATP非依赖性周质（TRAP）转运蛋白结合Neu5Ac的分子决定因素	Goyal, P.	PDF	N/A	Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter
现实世界任务中的反馈操作不会改变运动学习机制	Nardi, F.	PDF	N/A	Motor Learning Mechanisms are not modified by Feedback Manipulations in a Real-World Task
在产生烟灰的气候灾难后，谷类作物地方品种的适应不良	McLaughlin, C.	PDF	N/A	Maladaptation in cereal crop landraces following a soot-producing climate catastrophe
大肠杆菌在半干银、铜、不锈钢和玻璃表面上的实验进化	Rosenberg, M.	PDF	N/A	Experimental evolution of Escherichia coli on semi-dry silver, copper, stainless steel, and glass surfaces
Lag3和PD-1通路在早期CD4+ T细胞激活过程中调控依赖于NFAT的TCR信号传导程序。	Sheriff, L.	PDF	N/A	Lag3 and PD-1 pathways regulate NFAT-dependent TCR signalling programmes during early CD4+ T cell activation
通过招募关键免疫细胞在水凝胶储库中生成炎症微环境，可提高mRNA疫苗的效力。	Meany, E. L.	PDF	N/A	Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines
成像空间转录组学揭示了转基因α-突触核病模型中病理易感性的分子模式	Horan-Portelance, L.	PDF	N/A	Imaging spatial transcriptomics reveals molecular patterns of vulnerability to pathology in a transgenic α-synucleinopathy model
Tunturi病毒分离株和宏基因组组装的病毒基因组为北极冻原土壤中酸杆菌门的病毒组提供了深入了解。	Demina, T.	PDF	N/A	Tunturi virus isolates and metagenome-assembled viral genomes provide insights into the virome of Acidobacteriota in Arctic tundra soils
孤儿基因对于果蝇（Drosophila melanogaster）中精子高效进入卵子是必不可少的。	Guay, S. Y.	PDF	N/A	An orphan gene is essential for efficient sperm entry into eggs in Drosophila melanogaster
转录因子TCF21在肾脏发育过程中对于Foxd1+基质祖细胞的细胞命运决定是必需的。	Finer, G.	PDF	N/A	The transcription factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development
人类和其他猿类端粒到端粒基因组中的非典型DNA	Smeds, L.	PDF	N/A	Non-canonical DNA in human and other ape telomere-to-telomere genomes
通过考虑树突计算来克服运动传感器模型的局限性	Luna, R.	PDF	N/A	Overcoming the limitations of motion sensor models by considering dendritic computations
评估《昆明-蒙特利尔全球生物多样性框架》监测框架的覆盖范围及填补空白的机遇。	Affinito, F.	PDF	N/A	Assessing coverage of the Monitoring Framework of the Kunming-Montreal Global Biodiversity Framework and opportunities to fill gaps.
一种基于化合物生物活性谱的条件扩散模型，用于预测高内涵图像	Cook, S.	PDF	N/A	A diffusion model conditioned on compound bioactivity profiles for predicting high-content images
测试的测试：利用基于连接组学的预测模型揭示标准化测试和临床症状所反映的系统	Samardzija, A.	PDF	N/A	Testing the Tests: Using Connectome-Based Predictive Models to Reveal the Systems Standardized Tests and Clinical Symptoms Are Reflecting
因果枢纽：复杂疾病中遗传异质性和变异发现的结构化方法	Shaw, C. A.	PDF	N/A	The Causal Pivot: A Structural Approach to Genetic Heterogeneity and Variant Discovery in Complex Diseases
多尺度基于云的神经电生理分析与可视化管道	Geng, J.	PDF	N/A	Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization
UniversalEPI：利用注意力机制解码稀有和未探索细胞类型中的染色质相互作用	Grover, A.	PDF	N/A	UniversalEPI: Harnessing Attention Mechanisms to Decode Chromatin Interactions in Rare and Unexplored Cell Types
SPE-CZE-MS 能够定量测定磷酸化肽的仄摩尔浓度。	Serrano, L. R.	PDF	N/A	SPE-CZE-MS quantifies zeptomole concentrations ofphosphorylated peptides
抗体通过配体模拟和变构干扰来破坏细菌的粘附。	Hvorecny, K. L.	PDF	N/A	Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
解读结直肠癌与肝细胞相互作用：一种用于探究肝脏-肿瘤微环境中代谢交叉对话的多组学平台	Nelson, A. B.	PDF	N/A	Deciphering Colorectal Cancer-Hepatocyte Interactions: A Multiomic Platform for Interrogation of Metabolic Crosstalk in the Liver-Tumor Microenvironment
静息状态下人体骨骼肌分子特征的性别二态性及其对急性运动和耐力训练的反应	Dreher, S. I.	PDF	N/A	Sexual dimorphism in molecular profiles of resting human skeletal muscle and the response to acute exercise and endurance training
叶绿体代谢中三种酶的同时过表达未能提高二氧化碳同化或生物量。	Lemonnier, P.	PDF	N/A	Simultaneous Overexpression of Three Enzymes of Chloroplast Metabolism Fails to Improve CO2 Assimilation or Biomass.
鉴定髓样蛋白激酶C-ε为一个新型抗动脉粥样硬化基因	Binrouf, R. H.	PDF	N/A	Identification of Myeloid Protein Kinase C - Epsilon as a Novel Atheroprotective Gene
椎间盘细胞通过受体重排和代谢酶补充维持微环境及细胞稳态的小型细胞外囊泡	Samanta, A.	PDF	N/A	Small Extracellular Vesicles by Nucleus Pulposus Cells Maintain Niche and Cell Homeostasis via Receptor Shuffling and Metabolic Enzyme Supplements
14-3-3 epsilon通过抑制Plk1和Separase的活性，抑制了中心粒的过早脱离。	Jaiswal, M. A.	PDF	N/A	14-3-3 epsilon inhibits premature centriole disengagement by inhibiting the activity of Plk1 and Separase.
长读段测序的Caviid γ疱疹病毒1：编译全面的RNA图谱	Boldogkoi, Z.	PDF	N/A	Long-read Transcriptomics of Caviid Gammaherpesvirus 1: Compiling a Comprehensive RNA Atlas
泛癌N-糖蛋白质组图谱揭示FAT2为头颈癌的治疗靶点	Govindarajan, M.	PDF	N/A	Pan-cancer N-glycoproteomic atlas of patient derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers
在英国初级诊疗实践中诊断为血管肉瘤的犬的生存时间和预后因素	Taylor, C.	PDF	N/A	Survival time and prognostic factors in dogs diagnosed with haemangiosarcoma in UK first opinion practice
M102，一种用于肌萎缩侧索硬化症神经保护的NRF2和HSF-1双重激活剂。	Shaw, P. J.	PDF	N/A	M102, a combined NRF2 and HSF-1 activator for neuroprotection in amyotrophic lateral sclerosis.
MMETHANE：一种可解释的人工智能，用于从微生物组组成和代谢组学数据预测宿主状态	Dawkins, J. J.	PDF	N/A	MMETHANE: interpretable AI for predicting host status from microbial composition and metabolomics data
利用超高通量辐射快速灭菌临床血浆分离术血液制品	Melemenidis, S.	PDF	N/A	Rapid Sterilization of Clinical Apheresis Blood Products using Ultra-High Dose Rate Radiation
伤寒沙门氏菌的伤寒毒素在急性伤寒热期间引发宿主的抗菌反应。	Srour, S.	PDF	N/A	Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever
细胞壁合成的撞击逃逸：LpoB通过一个保守的变构开关短暂结合并激活PBP1b。	Shlosman, I.	PDF	N/A	The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch.
CarSR双组分系统直接调控radD表达，作为全局调节因子感知具核梭杆菌中的细菌共聚集现象	G C, B.	PDF	N/A	The CarSR Two-Component System Directly Controls radD Expression as a Global Regulator that Senses Bacterial Coaggregation in Fusobacterium nucleatum
核小体中Set2和RNAPII延伸复合体介导的转录偶联H3K36三甲基化的结构基础	Kujirai, T.	PDF	N/A	Structural basis of transcription-coupled H3K36 trimethylation by Set2 and RNAPII elongation complex in the nucleosome
β-心脏肌球蛋白在超松弛状态和无序松弛状态之间的动力学	Cail, R. C.	PDF	N/A	Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states
氧化还原依赖的结合和构象平衡调控活细胞中NAD(P)H的荧光衰减	Blacker, T. S.	PDF	N/A	Redox-dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells
工程化脯氨酰羟化酶依赖的蛋白质水解作用使得在植物中对缺氧反应进行正交控制成为可能	Shukla, V.	PDF	N/A	Engineering prolyl hydroxylase-dependent proteolysis enables the orthogonal control of hypoxia responses in plants
一种互利共生模式的细菌通过第六型分泌系统对非共生宿主具有致命性。	Gaddy, K. E.	PDF	N/A	A mutualistic model bacterium is lethal to non-symbiotic hosts via the type VI secretion system
通过邻近标记蛋白质组学研究上皮细胞细菌感染过程中CD9相互作用组的动力学	Wolverson, P. A.	PDF	N/A	Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics
沙门氏菌多突变体能够有效识别SPI-2效应蛋白在肠道炎症和全身定殖中的功能	Newson, J. P. M.	PDF	N/A	Salmonella multimutants enable efficient identification of SPI-2 effector protein function in gut inflammation and systemic colonization
Sp140L是一种新型的疱疹病毒限制因子。	Cable, J. M.	PDF	N/A	Sp140L Is a Novel Herpesvirus Restriction Factor
MaAsLin 3：优化并扩展元基因组关联发现的广义多元线性模型	Nickols, W. A.	PDF	N/A	MaAsLin 3: Refining and extending generalized multivariable linear models for meta-omic association discovery
多重碱基编辑BCL11A调控元件以治疗镰状细胞病	Fontana, L.	PDF	N/A	Multiplex base editing of BCL11A regulatory elements to treat sickle cell disease
古菌基因组中的II类内含子与真核剪接体内含子的进化起源	Mattick, J. S. A.	PDF	N/A	Group II Introns in Archaeal Genomes and the Evolutionary Origin of Eukaryotic Spliceosomal Introns
利用橙色发光碳纳米点作为荧光探针的超分辨率线粒体网络结构成像	Nandi, C. K.	PDF	N/A	Super Resolved Structural Imaging of Mitochondrial Network using Orange Emissive Carbon Nanodot as Fluorescent Probe
特定磷酸化模式在Tau-R4寡聚化中的作用	Bressler, S. G.	PDF	N/A	The role of specific phosphorylation patterns in the oligomerization of Tau-R4
YibN是一种与YidC相互作用的真正互作蛋白，与膜蛋白插入和膜脂质生成有关。	Zhao, Z.	PDF	N/A	YibN, a bona fide interactor of YidC with implications in membrane protein insertion and membrane lipid production
亮氨酸氨肽酶LyLAP能够促进溶酶体对膜蛋白的降解。	Jain, A.	PDF	N/A	Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins
# BioRxiv 2024-12-13 Papers

标题	作者	PDF链接	代码仓库	Title
感觉体验通过涉及degenerins的不同途径控制树突结构和行为。	Inberg, S.	PDF	N/A	Sensory experience controls dendritic structure and behavior by distinct pathways involving degenerins
在概率性奖励学习过程中通过小鼠内侧前额叶皮层进行的变化点估计	Murphy, C. E.	PDF	N/A	Change point estimation by the mouse medial frontal cortex during probabilistic reward learning
去泛素化抑制剂与SARS-CoV-2木瓜样蛋白酶结合的活性分析及其在鼠感染模型中的抗病毒效果	Choudhary, S.	PDF	N/A	Activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease with antiviral efficacy in murine infection model
已撤回：Progranulin通过抑制磷脂酶sPLA2-IIA来控制神经炎症	Du, H.	PDF	N/A	WITHDRAWN: Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation
新皮层微电路和中间电路的建模与仿真。第二部分：生理学与实验	Isbister, J. B.	PDF	N/A	Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation
人工语言和自然语言是由相同的大脑机制处理的。	Malik-Moraleda, S.	PDF	N/A	Constructed languages are processed by the same brain mechanisms as natural languages
城市边缘地区的池塘水质是否会影响大型无脊椎动物的丰度和群落结构？	Hulot, F. D.	PDF	N/A	Do macroinvertebrate abundance and community structure depend on the quality of ponds located in peri-urban areas?
二元判别器助力基于GPT的蛋白质设计	Zeng, Z.	PDF	N/A	Binary Discriminator Facilitates GPT-based Protein Design
在实验范式中比较随机交配和定时交配的小鼠	Khurshid, M.	PDF	N/A	Comparing random and timed mating of mice in the experimental paradigm
2-氧戊二酸触发活性十二聚体甲烷八叠球菌谷氨酰胺合成酶的组装。	Herdering, E.	PDF	N/A	2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase
变异效应预测器与功能测定之间的相关性反映了其在临床分类中的表现。	Livesey, B. J.	PDF	N/A	Variant effect predictor correlation with functional assays is reflective of clinical classification performance
CRASH2p：自由活动动物中的闭环双光子成像	McNulty, P.	PDF	N/A	CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal
SaprotHub：让蛋白质建模变得触手可及，惠及所有生物学家	Su, J.	PDF	N/A	SaprotHub: Making Protein Modeling Accessible to All Biologists
通过PHORCE揭示了噬菌体扩增速率的极端多样性以及噬菌体与抗生素相互作用的复杂性。	Mulla, Y.	PDF	N/A	Extreme diversity of phage amplification rates and phage-antibiotic interactions revealed by PHORCE
视觉运动延迟变化感知中的基线依赖性差异	Vigh, G.	PDF	N/A	Baseline dependent differences in the perception of changes in visuomotor delay
决定成败的细菌基因组编辑之关键——碱基编辑技术	Rengifo-Gonzalez, M.	PDF	N/A	Make-or-break prime editing for bacterial genome engineering
对称性促进了脊椎动物血红蛋白中特异性和高阶化学计量的进化。	Cortez-Romero, C. R.	PDF	N/A	Symmetry facilitated the evolution of specificity and high-order stoichiometry in vertebrate hemoglobin
酵母类溶酶体液泡上的V-ATP酶解体是复制性衰老中溶酶体功能障碍的表型驱动因素	Hashmi, F.	PDF	N/A	V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is aPhenotypic Driver of Lysosome Dysfunction in Replicative Aging
使用sciRED进行可解释的单细胞因子分解	Pouyabahar, D.	PDF	N/A	Interpretable single-cell factor decomposition using sciRED
与造血障碍相关的DNA-GATA1结合改变的定量分析	Zambo, B.	PDF	N/A	Quantitative analysis of DNA-GATA1 binding alterations linked to hematopoietic disorders
乌库尼埃米病毒感染会导致蜱细胞培养中RNA结合蛋白组的广泛重塑。	Wilson, A.	PDF	N/A	Uukuniemi virus infection causes a pervasive remodelling of the RNA-binding proteome in tick cell cultures
量化生物物理因素对通过残余功能网络塑造大脑交流的影响	Nakuci, J.	PDF	N/A	Quantifying the influence of biophysical factors in shaping brain communication through remnant functional networks
阿塔卡马沙漠土壤生物多样性的层次模式：跨越生物尺度的洞察	Villegas, L.	PDF	N/A	Hierarchical Patterns of Soil Biodiversity in the Atacama Desert: Insights Across Biological Scales
O-特异性抗原的丧失塑造了铜绿假单胞菌在小鼠临床前肺部感染模型中的微生物地理分布。	Fraser, H.	PDF	N/A	Loss of O-specific antigen shapes Pseudomonas aeruginosa microbiogeography in murine preclinical pulmonary infection model
R-Loop的调控及线粒体基因组的稳定性需要5'-3'外切酶/切口内切酶OEX1的参与。	Schatz-Daas, D.	PDF	N/A	R-Loop control and mitochondria genome stability requires the 5'-3' exonuclease/flap-endonuclease OEX1
个体间基因表达的变异性意味着大脑偏好基因在各器官中的稳定调控。	Bucao, C. F.	PDF	N/A	Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs
脂肪源性间充质干细胞与视网膜色素上皮细胞在应激环境中的相互作用通过纳米管隧道进行	Gozel, M.	PDF	N/A	Adipose-derived Mesenchymal Stem Cells and Retinal Pigment Epithelial Cells Interactions in Stress Environment via Tunneling Nanotubes
阅读习得促使语言跨模态整合在左腹侧枕颞皮层中发生	Debska, A.	PDF	N/A	Reading Acquisition Drives Linguistic Cross-Modal Convergence in The Left Ventral Occipitotemporal Cortex
环境DNA与社区科学：城市蜻蜓调查的优势与局限	Uche-Dike, R.	PDF	N/A	Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys
Brisk：精确的资源高效型k-mers字典	Smith, C.	PDF	N/A	Brisk: Exact resource-efficient dictionary for k-mers
OMAnnotator：一种构建注释共识基因组序列的新方法	Bates, S.	PDF	N/A	OMAnnotator: a novel approach to building an annotated consensus genome sequence
大效应生活史基因组区域与大西洋鲑的功能形态特征相关	Aykanat, T.	PDF	N/A	Large effect life-history genomic regions are associated with functional morphological traits in Atlantic salmon
欧洲河七鳃鳗（Lampetra fluviatilis）和溪七鳃鳗（Lampetra planeri）全基因组组装的比较	Torresen, O. K.	PDF	N/A	Comparison of whole-genome assemblies of European river lamprey (Lampetra fluviatilis) and brook lamprey (Lampetra planeri)
利用合成血清标志物进行体内转录监测	Watanabe, S.	PDF	N/A	Monitoring in vivo transcription with synthetic serum markers
基准测试人体步态模拟的预测能力。	Afschrift, M.	PDF	N/A	Benchmarking the predictive capability of human gait simulations.
丘脑网状核亚群的生物物理建模及其对网络动力学的不同贡献	Litvak, P.	PDF	N/A	Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to network dynamics
在一年生植物的有性生殖分配实验进化过程中，处理效应的重复性以及群体间的差异	Villamil, N.	PDF	N/A	Replication of treatment effects and differences among populations during experimental evolution of sex allocation in an annual plant
基于蛋白质冠的纳米组学对细菌病原体感染后植物应激生物标志物的深度分析	Coreas, R.	PDF	N/A	Deep profiling of plant stress biomarkers following bacterial pathogen infection with protein corona based nano-omics
与NGAL基因的多效性作用相关的发展性重连NGAL/CUC/KLU网络	Nicolas, A.	PDF	N/A	Developmental rewiring of the NGAL/CUC/KLU network associated with pleiotropic roles of NGAL genes
一种基于针状的双功能VOC传感平台，用于快速蔬菜质量检测	Hossain, O.	PDF	N/A	A Dual-Functional Needle-Based VOC Sensing Platform for Rapid Vegetable Quality Examination
植物-病原体相互作用的代谢建模量化了导致细菌性枯萎病的代谢瓶颈。	Gerlin, L.	PDF	N/A	Metabolic modeling of a plant-pathogen interaction quantifies the metabolic bottlenecks underlying bacterial wilt
整合组学揭示了小麦水分利用效率和抗旱性的遗传基础及TaMYB7-A1的功能	Xiao, J.	PDF	N/A	Integrative Omics reveals genetic basis and TaMYB7-A1's function in wheat WUE and drought resilience
决定温带适应型高粱开花时间变异的基因和通路	Mangal, H.	PDF	N/A	Genes and pathways determining flowering time variation in temperate adapted sorghum
使用大规模RNA-seq数据集预测植物性状	Hadish, J. A. A.	PDF	N/A	Predicting plant traits using large conglomerate RNA-seq datasets
使用物种分布模型将潜在的太平洋植物入侵者列入黑名单时存在不确定性	Holle, V.	PDF	N/A	Uncertainty in blacklisting potential Pacific plant invaders using species distribution models
在中部蒙特沙漠中，食虫鸟类对植物选择中猎物丰富度和叶结构的影响	Guerra-Navarro, C.	PDF	N/A	Effects of prey abundance and foliage structure in plant selection by insectivorous birds in the central Monte desert
年龄和性别影响狮尾猕猴（Macaca silenus）对本地和非本地植物种子的传播。	K, B.	PDF	N/A	Age and sex influence seed dispersal of native and non-native plants by Lion-tailed Macaques Macaca silenus
无需参考的辅助染色体鉴定与泛基因组分析在主要植物病原真菌中的应用	van Westerhoven, A.	PDF	N/A	Reference-free identification and pangenome analysis of accessory chromosomes in a major fungal plant pathogen
短尾调控语法和脊索起源的深层同源性	Fan, T.-P.	PDF	N/A	Deep homology of a brachyury regulatory syntax and origin of the notochord
基准测试用于生物学上保守的单细胞整合的深度学习方法	Yi, C.	PDF	N/A	Benchmarking deep learning methods for biologically conserved single-cell integration
卷曲螺旋结构域对生物分子凝聚物相行为的影响	He, Z.	PDF	N/A	The Impact of Coiled-Coil Domains on the Phase Behavior of Biomolecular Condensates
基于个性化多尺度模拟的股骨生长预测：力学生物学模型的验证与敏感性分析	Koller, W.	PDF	N/A	Femoral bone growth predictions based on personalized multi-scale simulations: Validation and sensitivity analysis of a mechanobiological model
鉴定和药理学表征游离脂肪酸1受体上的多个变构结合位点	Venka, K.	PDF	N/A	Identification and Pharmacological Characterization of Multiple Allosteric Binding Sites on the Free Fatty Acid 1 Receptor
研究小脑在慢步态适应中的控制作用：从分带行走的预测模拟中获得的见解	Fleischmann, S.	PDF	N/A	Investigating cerebellar control in slow gait adaptations: Insights from predictive simulations of split-belt walking
一个小分子增强了 arrestin-3 与 β2-肾上腺素能受体的结合	Kurt, H.	PDF	N/A	A small molecule enhances arrestin-3 binding to the β2-adrenergic receptor
由乙酰辅酶A和S-腺苷甲硫氨酸耗竭引起的表观遗传重编程是一条进化上古老的通向恶性生长的途径。	Chen, Z.	PDF	N/A	Epigenetic reprogramming induced by Acetyl-CoA and SAM depletion is an evolutionarily-ancient path to malignant growth
耕作中的紧张关系：减少耕作强度与小麦生长和营养谷物质量的降低相关，尽管土壤生物指标有所改善	Waibel, M.	PDF	N/A	Tensions in tillage: Reduction in tillage intensity associates with lower wheat growth and nutritional grain quality despite enhanced soil biological indicators
通过基于角蛋白的水凝胶递送阿托伐他汀的抗纤维化作用	Carroll, E. A.	PDF	N/A	Anti-fibrotic Effects of Atorvastatin Delivered via Keratin-based Hydrogels
多组学整合的可视化神经网络：一项关键性综述	Selby, D. A.	PDF	N/A	Visible neural networks for multi-omics integration: a critical review
基于监督表示学习的组织特异性细胞类型注释，采用分割向量量化方法及其与单细胞基础模型的比较	Heryanto, Y. D.	PDF	N/A	Tissue-Specific Cell Type Annotation with Supervised Representation Learning using Split Vector Quantization and Its Comparisons with Single-cell Foundation Models
细胞表面拥挤是一种可调节的生物物理屏障，影响细胞间的融合。	Lee, D. S. W.	PDF	N/A	Cell surface crowding is a tunable biophysical barrier to cell-cell fusion
蛋白质语言模型识别出驱动相分离的无序、保守基序	Zhang, Y.	PDF	N/A	Protein Language Model Identifies Disordered, Conserved Motifs Driving Phase Separation
关于革兰氏阴性菌中周质伴侣作为蛋白质折叠和转运调节因子的机制性见解	Haldar, S.	PDF	N/A	Mechanistic Insights into Periplasmic Chaperones as Regulators of Protein Folding and Translocation in Gram-Negative Bacteria
表观遗传调控因子BAP1的破坏会驱动染色质重塑，从而促使具有乳腺癌干细胞特性和异常糖基化的细胞出现。	Araujo, M. G. d. S.	PDF	N/A	Disruption of the epigenetic regulator BAP1 drives chromatin remodeling leading to the emergence of cells with breast cancer stem cell properties and aberrant glycosylation.
钠-葡萄糖共转运蛋白2抑制剂托格列净通过激活Kv通道、SERCA泵以及sGC/cGMP通路来诱导血管舒张。	Park, W. S.	PDF	N/A	The sodium-glucose cotransporter 2 inhibitor tofogliflozin induces vasodilation by activating Kv channels, the SERCA pump, and the sGC/cGMP pathway
一种肠道微生物-肌肉轴，通过调节秀丽隐杆线虫的线粒体分裂，保护其免受与年龄相关的运动能力下降。	Dennis, N.	PDF	N/A	A gut-microbiota-muscle axis that protects against age-related motor decline by regulating mitochondrial fission in C. elegans
锌是精子特异性钾通道（Slo3）功能的关键调节因子	Andriani, R. T.	PDF	N/A	Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function
一种用于预测真菌物种表观遗传学基因表达的混合机器学习模型	Weinstock, L.	PDF	N/A	A hybrid machine learning model for predicting gene expression from epigenetics across fungal species
大肠杆菌转录因子通过一种普遍的、稳态的机制调节启动子活性。	Parisutham, V.	PDF	N/A	E. coli transcription factors regulate promoter activity by a universal, homeostatic mechanism
单次使用赛洛西宾后大鼠前额叶皮层网络的短期和长期重组	Purple, R. J.	PDF	N/A	Short- and long-term reconfiguration of rat prefrontal cortical networks following single doses of psilocybin
基于网络的β淀粉样蛋白病理预测认知正常老年人的后续认知下降	He, H.	PDF	N/A	Network-based amyloid-beta pathology predicts subsequent cognitive decline in cognitively normal older adults
洪堡企鹅（Spheniscus humboldti, Meyen, 1834）在秘鲁钦博特的埃尔费罗尔湾的出现及其保护策略	Loayza-Aguilar, R. E.	PDF	N/A	Occurrence of the Humboldt Penguin (Spheniscus humboldti, Meyen, 1834) in El Ferrol Bay, Chimbote, Peru, and strategies for its conservation
核小体动力学使活体人细胞中的异染色质变得可及。	Prajapati, H. K.	PDF	N/A	Nucleosome dynamics render heterochromatin accessible in living human cells
一种新型甘露聚糖特异性嵌合抗原受体M-CAR能够引导T细胞与念珠菌属菌丝及米根霉孢子相互作用。	Guimaraes, J. G.	PDF	N/A	A novel Mannan-specific chimeric antigen receptor M-CAR redirects T cells to interact with Candida spp. hyphae and Rhizopus oryzae spores
Galectin-1通过调节糖酵解来调控肝细胞癌对热消融的反应。	Nguyen, T.	PDF	N/A	Galectin-1 Modulates Hepatocellular Carcinoma Response to Thermal Ablation Through Regulating Glycolysis
揭示欧洲蝰蛇及其毒液的进化历史：一种多组学方法	Talavera, A.	PDF	N/A	Unveiling the evolutionary history of European vipers and their venoms from a multi-omic approach
水生理学核磁共振揭示了神经组织中稳态水交换的机制	Williamson, N. H.	PDF	N/A	Hydrophysiology NMR reveals mechanisms of steady-state water exchange in neural tissue
多巴胺通过D1样受体调节间隙连接耦合，调控AII无长突细胞的膜电位和甘氨酸释放。	Strazza Junior, P.	PDF	N/A	Dopamine regulates the membrane potential and glycine release of AII amacrine cells via D1-like receptor modulation of gap junction coupling.
免疫-RCA在印刷糖阵列上高灵敏度检测ABO血型抗体的应用	Kornilova, E. E.	PDF	N/A	The applying of immuno-RCA for the high-sensitivity detection of the ABO blood group antibodies on the printed glycoarray
关于塑造淡水碎屑食物网的流域土地覆盖变化的综合分析	Oester, R.	PDF	N/A	A global synthesis on land-cover changes in watersheds shaping freshwater detrital food webs
三种新海洋纤毛虫物种的形态学和分子系统发育特征	Phanprasert, Y.	PDF	N/A	Morphological and Molecular Phylogenetic Characterization of Three New Marine Goniomonad Species
动物中高累积的流感病毒滴度与显著的疾病致死率表明，在致死率与传播性之间可能存在一种权衡关系。	Gouveia, A. S.	PDF	N/A	High cumulative viral titers of influenza virus in animals with significant disease fatality rates indicate a potential trade-off between fatality and transmissibility
选择对生产代价高昂的毒素的强度随着生长速率的增加而增强。	Bisesi, A.	PDF	N/A	The strength of selection for costly toxin production increases with growth rate.
血管紧张素肽增强SARS-CoV-2刺突蛋白与其宿主细胞受体的结合	Oliveira, K. X.	PDF	N/A	Angiotensin peptides enhance SARS-CoV-2 spike protein binding to its host cell receptors
H2B.W2是一种特异性于精母细胞的组蛋白变体，它破坏了核小体的稳定性并降低了染色质的压缩程度。	NGUYEN, T. T.	PDF	N/A	H2B.W2, a Spermatocytes-specific Histone Variant, disrupts nucleosome stability and reduces chromatin compaction
库欣综合征缓解后股骨颈的生物力学弹性：基于QCT的有限元模型的比较分析	Soudah Prieto, E.	PDF	N/A	Biomechanical resilience of the femoral neck post-remission of Cushing's Syndrome: a comparative analysis using QCT-based Finite Element models
计算机模拟比较恶性疟原虫新蛋白质作为抗疟疾候选药物靶点	Surya, A. M. G.	PDF	N/A	In silico Comparison of Novel Proteins from Plasmodium Falciparum as Candidate Drug Targets against Malaria
SARS-CoV2变异过程中RBD/hACE2界面微妙变化的分子动力学研究	Gheeraert, A.	PDF	N/A	Subtle changes at the RBD/hACE2 interface during SARS-CoV2 variant evolution: a molecular dynamics study
利用Nanoendoscopy-AFM直接压痕技术探测纳米力学揭示了癌细胞中的核弹性转变	Ichikawa, T.	PDF	N/A	Probing nanomechanics by direct indentation using Nanoendoscopy-AFM reveals the nuclear elasticity transition in cancer cells
COVID-19中肺动脉重构的组织病理学评估	Gychka, S. G.	PDF	N/A	Histopathological Evaluation of Pulmonary Arterial Remodeling in COVID-19
SUMO E1共价别构抑制剂通过MAT2A-AdoMetDC轴调节多胺合成。	Zhang, S.	PDF	N/A	SUMO E1 covalent allosteric inhibitors modulate polyamine synthesis via the MAT2A-AdoMetDC axis
一种新颖且稳健的方法，用于评估健康和患病冷冻心脏组织中的线粒体（功能障碍）功能	Hu, L.	PDF	N/A	A novel and robust method for assessing mitochondrial (dys)function in healthy and diseased frozen cardiac tissue
基于数据的细胞类型导向网络校正组合疗法在阿尔茨海默病中的发现	Li, Y.	PDF	N/A	Data-driven discovery of cell-type-directed network-correcting combination therapy for Alzheimer's disease
使用一维卷积神经网络对视觉意象和想象语音脑机接口进行分类	Le, D.	PDF	N/A	Classification of Visual Imagery and Imagined Speech EEG based Brain Computer Interfaces using 1D Convolutional Neural Network
成纤维细胞和壁细胞亚群在神经性疼痛模型中的作用。	Villa-Hernandez, S.	PDF	N/A	A role for fibroblast and mural cell subsets in models of neuropathic pain.
改变的嘌呤能信号传导和CD8+ T细胞功能失调在STAT3功能获得综合征中的表现	Duran, J. S. C.	PDF	N/A	Altered Purinergic Signaling and CD8+ T Cell Dysregulation in STAT3 GOF Syndrome
SARS-CoV-2 Nsp14与Tollip结合，激活促炎性信号通路，同时下调干扰素α和干扰素γ受体。	Thakur, N.	PDF	N/A	SARS-CoV-2 Nsp14 binds Tollip and activates pro-inflammatory pathways while downregulating interferon alpha and interferon gamma receptors
内源性靶向微RNA降解位点簇引发特定微RNA家族的降解	Hiers, N. M.	PDF	N/A	An endogenous cluster of target-directed microRNA degradation sites induces decay of distinct microRNA families
通过实验进化揭示的性别分配权衡及其遗传结构	Gerchen, J. F.	PDF	N/A	Sex-allocation trade-offs and their genetic architecture revealed by experimental evolution
染色体的可塑性可以推动细菌的快速适应。	Vega-Cabrera, L.	PDF	N/A	Chromosomal plasticity can drive rapid adaptation in bacteria
雄性小鼠没有对糖的偏好行为。	Pan, T.	PDF	N/A	Male Mice Have no Sugar-preference Behavior
从整合的转录组数据集中推断基因-通路关联：用于嗜热四膜虫的交互式基因网络浏览器	Bertagna, M. A.	PDF	N/A	Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for Tetrahymena thermophila
运动想象和实际执行激活了相似的手指表征，这些表征在时间上是空间一致的。	Odermatt, I. A.	PDF	N/A	Motor imagery and execution activate similar finger representations that are spatially consistent over time
肽信息压缩技术（PICT）：治疗性肽发现的新前沿	Wang, H.	PDF	N/A	Peptide Information Compression Technology (PICT): A New Frontier in Therapeutic Peptide Discovery
两种蜜蜂物种——西方蜜蜂（Apis mellifera）和日本东方蜜蜂（Apis cerana japonica）的综合表达数据	Yokoi, K.	PDF	N/A	Comprehensive expression data for two honey bee species, Apis mellifera and Apis cerana japonica
Cuf1转录因子富含半胱氨酸的结构域对于高铜胁迫感应和真菌毒力是必需的。	Probst, C.	PDF	N/A	A cysteine-rich domain of the Cuf1 transcription factor is required for high copper stress sensing and fungal virulence
六种细菌暴露于六类抗生素下的共敏感性和交叉抗性	Wang, X. H.	PDF	N/A	Collateral sensitivity and cross resistance in six species of bacteria exposed to six classes of antibiotics
酶促差向异构化在卡痛中的单萜吲哚生物碱	McDonald, A.	PDF	N/A	Enzymatic epimerization of monoterpene indole alkaloids in Kratom
PEX1G843D在过氧化物酶体生物发生中仍保持功能，但会被蛋白酶体迅速降解。	Sheedy, C. J.	PDF	N/A	PEX1G843D remains functional in peroxisome biogenesis but is rapidly degraded by the proteasome
数据非依赖性采集结合电子活化解离技术，用于深入解析羟基脂肪酸酯的结构	Kurizaki, Y.	PDF	N/A	Data-independent acquisition coupled with electron-activated dissociation for in-depth structure elucidation of fatty acid ester of hydroxy fatty acids
开发一种增强的抗泛N-甲酰甲硫氨酸特异性抗体	Kim, D.	PDF	N/A	Development of an enhanced anti-pan-N-formylmethionine-specific antibody
SETD2协同转录的H3K36甲基化的分子机制	Walshe, J. L.	PDF	N/A	Molecular mechanism of co-transcriptional H3K36 methylation by SETD2
CRISPR编辑的DPSCs，持续表达BDNF，增强受损牙齿的牙本质再生	Kim, J. H.	PDF	N/A	CRISPR-Edited DPSCs, Constitutively Expressing BDNF Enhance Dentin Regeneration in Injured Teeth
PhyloCNN：在系统动力学和多样化研究中，通过改进树的表示和神经网络架构来提升从树中进行深度学习的效果	Perez, M. F.	PDF	N/A	PhyloCNN: Improving tree representation and neural network architecture for deep learning from trees in phylodynamics and diversification studies
人类DNA中进一步的古代内源性逆转录病毒变种	Frith, M.	PDF	N/A	Further varieties of ancient endogenous retrovirus in human DNA
解卷积依赖TCR与不依赖TCR的激活对于通过AIM测定进行可靠的抗原特异性CD4+ T细胞表征至关重要。	Zheng, M. Z. M.	PDF	N/A	Deconvoluting TCR-dependent & -independent activation is vital for reliable Ag-specific CD4+ T cell characterization by AIM assay
通过黄蝶呤生物合成途径基因调控黄曲霉H-1形态、分生孢子生成及紫色色素合成	Ran, Y.	PDF	N/A	Regulation of Fungal Morphology, Conidiogenesis and Violet Pigment Synthesis by the Betalain Biosynthesis Pathway Genes in Aspergillus sydowii H-1
零价硫是同化型亚硫酸盐还原酶的产物，也是半胱氨酸合酶的底物。	Liu, H.	PDF	N/A	Zero valent sulfur is the product of assimilatory sulfite reductase and a substrate of cysteine synthase
脑心肌炎病毒非结构蛋白2C通过降解NDP52自噬蛋白以促进其自身存活	Mo, R.	PDF	N/A	Encephalomyocarditis virus non-structural protein 2C degrades NDP52 autophagy protein to promote its own survival
利用PTasRNA技术通过pMEGA质粒靶向清除改造海洋假交替单胞菌TAC125	Severino, A.	PDF	N/A	Engineering the Marine Pseudoalteromonas haloplanktis TAC125 via pMEGA Plasmid Targeted Curing Using PTasRNA Technology
多组学映射肠道微生物群在孕酮代谢中的作用	Mong, G.-J. B.	PDF	N/A	Multi-Omics Mapping of Gut Microbiota's Role in Progesterone Metabolism
RNA病毒的发现揭示了主要葡萄园害虫——欧洲葡萄蛾（Lobesia botrana）的病毒组情况。	Debat, H. J.	PDF	N/A	RNA virus discovery sheds light on the virome of a major vineyard pest, the European grapevine moth (Lobesia botrana)
通过-MaP和-JuMP揭示的由倒置Alu介导的反向剪接的结构决定因素	Waldern, J. M.	PDF	N/A	Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP
对PBMCs和供体匹配的iPSCs中DNA甲基化的表征显示，在干细胞重编程过程中，甲基化被重置。	Reed, X.	PDF	N/A	Characterization of DNA methylation in PBMCs and donor-matched iPSCs shows methylation is reset during stem cell reprogramming
癌症相关生物标志物的多重甲基化特异性qPCR的系统设计	Wang, J.	PDF	N/A	Systematic Design of Multiplex Methylation-Specific qPCR for Cancer-Related Biomarkers
利用基因组技术在多花黄精中发现了二苯乙烯类基因簇	Jiang, J.	PDF	N/A	Genome-enabled stilbenoid gene cluster discovery in Pleuropterus multiflorus
在Dictyostelium中，细胞外腺苷脱氨作用促进了顶端组织者的发育。	Hathi, P.	PDF	N/A	Extracellular adenosine deamination primes tip organizer development in Dictyostelium
一个用于定量分析遗传缓冲的数学框架	Karagiannis, J.	PDF	N/A	A Mathematical Framework for the Quantitative Analysis of Genetic Buffering
通过化学诱导染色体相互作用进行Hi-C校准	Li, Y.	PDF	N/A	Hi-C Calibration by Chemically Induced Chromosomal Interactions
哺乳动物蛋白MTCH1可以作为插入酶发挥作用。	Dimogkioka, A. R.	PDF	N/A	The mammalian protein MTCH1 can function as an insertase
在E.coli中表达TNFR1 R347A、MyD88和IRAK4死亡结构域，随后进行纯化并对其中的TNFR1 R347A死亡结构域进行生物物理特性分析。	Przytulski, K.	PDF	N/A	Expression screen of TNFR1 R347A, MyD88, IRAK4 death domains in E. coli followed by purification and biophysical characterization of TNFR1 R347A death domain
制药放行分析中仪器变更的通用研究设计	Ries, A. B.	PDF	N/A	Universal Study Design for Instrument Changes in Pharmaceutical Release Analytics
基于点击化学的双向生物正交方法用于检测和鉴定骨关节炎研究中的蛋白质赖氨酸丙二酰化	Binoy, A.	PDF	N/A	A click chemistry-based biorthogonal approach for the detection and identification of protein lysine malonylation for osteoarthritis research
通过腺相关病毒递送实现小鼠体细胞组织的线粒体腺苷碱基编辑	Mutti, C. D.	PDF	N/A	Mitochondrial adenine base editing of mouse somatic tissues via adeno-associated viral delivery
LMX1B错义扰动调节元件足迹破坏了5-羟色胺能前脑轴突的分枝结构。	Eastman, B. A.	PDF	N/A	LMX1B missense-perturbation of regulatory element footprints disrupts serotonergic forebrain axon arborization
数据驱动的突触分类揭示了谷氨酸受体组成的逻辑	Micheva, K. D.	PDF	N/A	Data-driven synapse classification reveals a logic of glutamate receptor composition
甲状腺激素作为计时器，调控小鼠新皮层中小清蛋白神经元的产后成熟过程。	Ren, J.	PDF	N/A	Thyroid hormones act as a timer for the postnatal maturation of parvalbumin neurons in mouse neocortex
由于斑马鱼中Pax9基因突变导致的面部中部凹陷和面部附属器官缺失	Paudel, S.	PDF	N/A	Midfacial retrusion and loss of facial appendages caused by mutation of Pax9 in zebrafish
在新石器时代的卡塔许尤克遗址中，通过古代DNA保存反映出的特定年龄段的埋葬习俗	Kücükakdag Dogu, A.	PDF	N/A	An age-specific burial practice reflected in ancient DNA preservation in Neolithic Catalhöyük
在家族内进行的GWAS（全基因组关联研究）并未能改善跨群体预测准确性的下降。	Zhang, L.	PDF	N/A	Within-Family GWAS does not Ameliorate the Decline in Prediction Accuracy across Populations
单个神经元的多样性支持了视觉皮层通路沿线的区域功能特化。	Feyerabend, M.	PDF	N/A	Single neuron diversity supports area functional specialization along the visual cortical pathways
人类海马体中的θ震荡组织了目标距离编码	Huang, Z.	PDF	N/A	Human Hippocampal Theta Oscillations Organise Distance to Goal Coding
GABA、谷氨酸动态以及在具有幻觉特征的精神病患者进行认知处理期间观察到的BOLD信号	Craven, A. R.	PDF	N/A	GABA, Glutamate dynamics and BOLD observed during cognitive processing in psychosis patients with hallucinatory traits
围产期血清素信号传导动态地影响皮质GABA能回路的发育，其结果对终身的感官编码产生影响。	Ocana-Santero, G.	PDF	N/A	Perinatal serotonin signalling dynamically influences the development of cortical GABAergic circuits with consequences for lifelong sensory encoding
Dlx5/6在协调哺乳动物发声和听觉器官发育中的多效性功能	Sanchez-Garrido, F.	PDF	N/A	Pleiotropic function of Dlx5/6 in coordinating the development of mammalian vocal and auditory organs
高度多样化灵长类动物的岛屿殖民基因组特征	Colmonero-Costeira, I.	PDF	N/A	Genomic signatures of island colonization in highly diverse primates
# BioRxiv 2024-12-12 Papers

标题	作者	PDF链接	代码仓库	Title
疫苗增强的竞争允许肠道内细菌菌株的合理替换	Lentsch, V.	PDF	N/A	Vaccine-enhanced competition permits rational bacterial strain replacement in the gut
在NMDA受体抗体脑炎小鼠模型中，胼胝体连接的中断是导致长期感觉运动障碍的基础。	Zhou, J.	PDF	N/A	Disrupted callosal connectivity underlies long-lasting sensory-motor deficits in an NMDA receptor antibody encephalitis mouse model
对真菌蚊基因组（双翅目：粪生迟眼蕈蚊）进行染色体水平支架搭建	Urban, J. M.	PDF	N/A	Chromosome-scale scaffolding of the fungus gnat genome (Diptera: Bradysia coprophila)
经验改变了控制突触可塑性和学习的时机规则	Jayabal, S.	PDF	N/A	Experience Alters the Timing Rules Governing Synaptic Plasticity and Learning
出口蛋白1/XPO1核输出途径抑制对冠状病毒复制的影响。	Rahman, M. M.	PDF	N/A	Effect of exportin 1/XPO1 nuclear export pathway inhibition on coronavirus replication.
II类和III类病毒融合蛋白能够识别并重组复杂的生物膜结构。	Poojari, C. S.	PDF	N/A	Viral fusion proteins of class II and III recognize and reorganize complex biological membranes
一种新的管道SPICE识别出新的JUN-IKZF1复合元件	Li, P.	PDF	N/A	A new pipeline SPICE identifies novel JUN-IKZF1 composite elements
改善焦虑研究：通过多状态摘要指标揭示特质焦虑的新方法	Varga, Z. K.	PDF	N/A	Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states
单核细胞利用突出力在基于胶原蛋白的粘弹性细胞外基质中生成迁移路径。	Adebowale, K.	PDF	N/A	Monocytes use protrusive forces to generate migration paths in viscoelastic collagen-based extracellular matrices
乳腺癌细胞在脑转移阶段对肿瘤微环境的差异性适应与重塑	Wu, X.	PDF	N/A	Differential Adaptation and Remodeling of the Tumor Microenvironment in Breast Cancer Cells During the Stages of Brain Metastasis
光谱分解揭示了海鞘形态发生的过程	Dokmegang, J.	PDF	N/A	Spectral decomposition unlocks ascidian morphogenesis
在主动推理框架下人类决策中新颖性和变异性神经相关性	Zhang, S.	PDF	N/A	The Neural Correlates of Novelty and Variability in Human Decision-Making under an Active Inference Framework
癌症免疫疗法的效果在淋巴结切除后仍然持续。	Zhou, H.	PDF	N/A	Cancer immunotherapy response persists after lymph node resection
病毒基因组特征可预测正痘病毒的宿主	Tseng, K. K.	PDF	N/A	Viral genomic features predict orthopoxvirus reservoir hosts
早发性家族性阿尔茨海默病和Sanfilippo综合征斑马鱼模型的多组学分析揭示了疾病机制的共性	Barthelson, K.	PDF	N/A	Multi-omics analyses of early-onset familial Alzheimer's disease and Sanfilippo syndrome zebrafish models reveal commonalities in disease mechanisms
关于金鱼卵和胚胎的独立刺激性——关于金鱼卵中节律性卵黄收缩的活体交流	Sanchez, P. G. L.	PDF	N/A	On the independent irritability of goldfish eggs and embryos -- a living communication on the rhythmic yolk contractions in goldfish
越冬而非繁殖的海洋环境可能调节长途迁徙海鸟的存活率下降。	Snell, K.	PDF	N/A	Wintering, rather than breeding, oceanic conditions may modulate declining survival in a long-distance migratory seabird
vmrseq: 单细胞甲基化异质性的概率建模	Shen, N.	PDF	N/A	vmrseq: Probabilistic Modeling of Single-cell Methylation Heterogeneity
揭示丘脑深部脑刺激背后的网络机制	Tian, Y.	PDF	N/A	Uncovering network mechanism underlying thalamic deep brain stimulation
元代谢组生态学揭示了地球化学和微生物功能潜力与七条河流中有机质发展之间的联系。	Danczak, R. E.	PDF	N/A	Meta-metabolome ecology reveals that geochemistry and microbial functional potential are linked to organic matter development across seven rivers
自然主义对话中，社会和语义背景对语音编码的影响	Abassi, E.	PDF	N/A	Influence of social and semantic contexts on phonetic encoding in naturalistic conversations
癌症相关成纤维细胞如何促进人类肺癌中T细胞的排除：一个物理学的视角	Ackermann, J.	PDF	N/A	How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective
估计神经网络中的有效连接性：基于导数和基于相关性方法的比较	Laasch, N.	PDF	N/A	Estimating effective connectivity in neural networks: comparison of derivative-based and correlation-based methods
生物相容性钕掺杂纳米晶体作为衍射极限体外温度传感探针	Bravo, M.	PDF	N/A	Biocompatible Neodymium-Doped Nanocrystals as Probes for Diffraction-limited, in vitro Temperature Sensing
限时进食导致小鼠消化系统的性别和器官特异性反应	Oparija-Rogenmozere, L.	PDF	N/A	Time-restricted feeding leads to sex- and organ-specific responses in the murine digestive system
HippoMaps：人类海马结构的多尺度地图绘制	DeKraker, J.	PDF	N/A	HippoMaps: Multiscale cartography of the human hippocampal formation
在单个网格模块内，网格细胞属性的稳健变异性增强了局部空间的编码能力	Redman, W. T.	PDF	N/A	Robust variability of grid cell properties within individual grid modules enhances encoding of local space
在癌症FFPE样本中，RNA聚合酶II在组蛋白基因上的超转录	Henikoff, S.	PDF	N/A	RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples
55900种RNA病毒的元转录组综合分析揭示了RNA病毒组在全球污水处理厂中对人类健康的潜在影响及其生态角色	Yuan, L.	PDF	N/A	Metatranscriptomic Compendium of 55900 RNA Viruses Deciphers Human Health Implication and Ecological roles of RNA Virome in Global Wastewater Treatment Plants
道路密度简化了区域食物网。	Mestre, F.	PDF	N/A	Road density simplifies regional food webs
KaiC的初始磷酸化是由其自激酶自我抑制的释放所激活的。	Furuike, Y.	PDF	N/A	The priming phosphorylation of KaiC is activated by the release of its autokinase autoinhibition
额叶外区域在有意识运动行为中的作用：一项使用快速光学成像的注册报告	Colombari, E.	PDF	N/A	The role of extra-striate areas in conscious motor behavior: a registered report with Fast-Optical Imaging
HCF101是人类病原体刚地弓形虫（Toxoplasma gondii）中CIA胞质铁硫合成途径的新组分。	Renaud, E. A.	PDF	N/A	HCF101 is a novel component of the CIA cytosolic iron-sulfur synthesis pathway in the human pathogen Toxoplasma gondii
目标导向行为背后的视觉运动转换	Zhao, P.	PDF	N/A	The visuomotor transformations underlying target-directed behavior
一个在时间生物学上保守的复合体与秀丽隐杆线虫的发育时间相关。	Spangler, R. K.	PDF	N/A	A conserved chronobiological complex times C. elegans development
一种新的期望最大化方法，用于从时间序列遗传数据中推断一般二倍体选择	Fine, A. G.	PDF	N/A	A novel expectation-maximization approach to infer general diploid selection from time-series genetic data
在不同的神经决策信号中，对演化信念和瞬时信念更新的可分离编码	Pares-Pujolras, E.	PDF	N/A	Dissociable encoding of evolving beliefs and momentary belief updates in distinct neural decision signals
太平洋雨林中指示性莺类物种复合体的动态气候适应	Wang, S.	PDF	N/A	The dynamic climate adaptation of indicator warbler species complex in the Pacific Rainforest
骆驼科单域抗体对锥虫乳酸激酶的变构抑制	Pinto Torres, J. E.	PDF	N/A	Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody
植物圈中的挥发性有机化合物专家	Padaki, V. G.	PDF	N/A	Volatile Organic Compound Specialists in the Phycosphere
人类下丘中的快速和刺激特异性偏差检测	Wetekam, J.	PDF	N/A	Rapid and Stimulus-Specific Deviance Detection in the Human Inferior Colliculus
特发性震颤在自然运动过程中破坏了大脑的节律网络	West, T.	PDF	N/A	Essential Tremor Disrupts Rhythmic Brain Networks During Naturalistic Movement
一种由亲和力驱动的Twisted gastrulation调控细胞外BMP的机制	Moore, G.	PDF	N/A	An avidity-driven mechanism of extracellular BMP regulation by Twisted gastrulation
钠负荷正常血压小鼠血管重塑的性别相关差异	Silva, J. C. d. S.	PDF	N/A	Sex-related differences in vascular remodeling of sodium overloaded normotensive mice
局部核质比通过细胞周期状态调节H3.3的整合，在合子基因组激活期间发挥作用。	Bhatt, A. D.	PDF	N/A	Local nuclear to cytoplasmic ratio regulates H3.3 incorporation via cell cycle state during zygotic genome activation
发育中的鸡三叉神经节转录组图谱	Leonard, C. E.	PDF	N/A	The transcriptional landscape of the developing chick trigeminal ganglion
在南非的两个污水处理厂中检测到的隐孢子虫卵囊和贾第虫包囊	Gonose, T.	PDF	N/A	Cryptosporidium oocysts and Giardia cysts at two South African wastewater treatment plants
在条件学习过程中，延迟结果的信用分配的神经机制	Witkowski, P.	PDF	N/A	Neural mechanisms of credit assignment for delayed outcomes during contingent learning
血管紧张素转换酶中心模型：与计算的AT1受体和醛固酮水平相关的肽通量	Westwood, B. M.	PDF	N/A	Angiotensin Converting Enzyme Hub Model of Peptide Flux Relating Calculated AT1 Receptor and Aldosterone Levels
小鼠颅神经板空间和时间基因表达的单细胞图谱	Brooks, E. R.	PDF	N/A	A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate
功能性状和土壤水分可利用性塑造了二倍体-多倍体复合体中的竞争相互作用	Rodriguez-Parra, A.	PDF	N/A	Functional traits and soil water availability shape competitive interactions in a diploid-polyploid complex
大型齿鲸种内体长变化的总结	McClure, J.	PDF	N/A	A summary of intraspecific size variation for large odontocetes
一种统一的贝叶斯方法用于转录组关联研究	Khan, A. K.	PDF	N/A	A unified Bayesian approach to transcriptome-wide association study
鼻内给予锂盐可抑制大脑中的炎症性细胞焦亡，并改善5XFAD小鼠的记忆丧失和抑郁样行为。	Bhuiyan, P.	PDF	N/A	Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD mice
学习发育动力学的几何模型	Howe, A. E. S.	PDF	N/A	Learning geometric models for developmental dynamics
穴样蛋白-1调控尤文肉瘤中的环境依赖性信号传导与生存。	Segal, D.	PDF	N/A	Caveolin-1 regulates context-dependent signaling and survival in Ewing Sarcoma.
通过味觉受体检测细菌可启动细胞免疫反应	Mazariegos, A. N.	PDF	N/A	Detection of bacteria through taste receptors primes the cellular immune response
Meta2DB：用于健康状态预测的精选鸟枪法宏基因组特征集和元数据	Kok, C. R.	PDF	N/A	Meta2DB: Curated Shotgun Metagenomic Feature Sets and Metadata for Health State Prediction
在灵长类腹侧前运动皮层中时间感知期间的情境神经动力学	Diaz, H.	PDF	N/A	Contextual Neural Dynamics During Time Perception in Primate Ventral Premotor Cortex
单突触腹侧被盖区谷氨酸投射至蓝斑，增强厌恶情绪处理。	Parker, K. E.	PDF	N/A	Monosynaptic ventral tegmental area glutamate projections to the locus coeruleus enhance aversive processing
个体在政策精确性上的差异：与自杀意念及默认模式网络动态的关联	Yoon, D.	PDF	N/A	Individual Differences in Policy Precision: Links to Suicidal Ideation and Default Mode Network Dynamics
关系整合需求是通过高阶皮层网络中阿尔法和贝塔节律的时延神经表征来追踪的。	Robinson, C. N.	PDF	N/A	Relational integration demands are tracked by temporally delayed neural representations in alpha and beta rhythms within higher-order cortical networks
用于分析力激活蛋白延伸和相互作用的DNA纳米装置	Zhou, K.	PDF	N/A	DNA nanodevice for analysis of force-activated protein extension and interactions
小分子脂筏稳定性调节剂和蛋白质-筏分配调节剂	Stefanski, K. M.	PDF	N/A	Small-molecule modulators of lipid raft stability and protein-raft partitioning
氧化应激对腺苷A2a受体结构、功能及信号传导的影响	Company, I.	PDF	N/A	The effect of oxidative stress on the Adenosine A2a Receptor structure, activity and signalling
细菌核糖体中药物结合残基的演变	Ekemezie, C. L.	PDF	N/A	Evolution of drug-binding residues in bacterial ribosomes
肌肉基生物混合设备的低成本打印机使用的3D打印树脂的细胞毒性和特性研究	Liao, A. S.	PDF	N/A	Cytotoxicity and Characterization of 3D-Printable Resins Using a Low-Cost Printer for Muscle-based Biohybrid Devices
细节决定成败！多模态个性化能够提升经颅直流电刺激对感觉运动整合调节的疗效。	Radecke, J.-O.	PDF	N/A	Details matter! Multimodal personalization increases the efficacy of transcranial direct current stimulation for modulation of sensorimotor integration
机器学习揭示了胶质母细胞瘤和骨肉瘤的新型治疗靶点	Li, N.	PDF	N/A	Machine learning reveals novel targets for both glioblastoma and osteosarcoma
超声组织碎裂术与人类多能干细胞衍生的肝球植入术作为先天性代谢性肝病潜在治疗手段的安全性与有效性：在免疫健全的啮齿动物模型中的评估。	Rashidi, H.	PDF	N/A	The safety and efficacy of Ultrasound Histotripsy and human pluripotent stem cell-derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: assessment in an immunocompetent rodent model.
连续的感觉运动转换增强了猕猴运动皮层神经动力学对扰动的鲁棒性	Zheng, C.	PDF	N/A	Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex
基于机制的方法在设计针对无义突变疾病的个性化联合疗法中的应用	Bhat, S.	PDF	N/A	Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases
蛋白质语言可视化工具：语言模型时代的序列相似性网络	Espinoza Herrera, J.	PDF	N/A	The Protein Language Visualizer: Sequence Similarity Networks for the Era of Language Models
CellBinDB：一个大规模多模态注释细胞分割数据集，并附有通用模型的基准测试	Shi, C.	PDF	N/A	CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models
关键期信号通过线粒体活性氧（ROS）和缺氧诱导因子-1α（HIF-1α）指导神经系统发育。	Sobrid-Camean, D.	PDF	N/A	Critical period signalling directs nervous system development through mitochondrial ROS and HIF-1α
真核生物核糖体中药物结合残基的演变	Chan, L. I.	PDF	N/A	Evolution of drug-binding residues in eukaryotic ribosomes
热诱导的磷脂酰丝氨酸变化驱动HSPA1A在质膜的定位	Low, J.	PDF	N/A	Heat-Induced Phosphatidylserine Changes Drive HSPA1A's Plasma Membrane Localization
跨越上皮-间质转化（EMT）景观的过渡路径由网络逻辑决定。	Dey, A.	PDF	N/A	Transition paths across the EMT landscape are dictated by network logic
对已识别的果蝇神经元的突触进行分析，揭示了突触前活性区的细胞类型特异性空间排列。	Wu, H.	PDF	N/A	Synapse profiling of identified Drosophila neurons revealed cell-type-specific spatial configurations of presynaptic active zones
比较基因组学研究显示，立克次氏菌属细菌具有多种代谢特征，这些特征与其与节肢动物的共生相互作用有关。	Floriano, A. M. M.	PDF	N/A	Comparative genomics of Rickettsiella bacteria reveal variable metabolic traits involved in symbiotic interactions with arthropods
超分辨率成像揭示了CD81微区在调节Jurkat T细胞微绒毛膜信号传导中的空间组织	Ramseier, N.	PDF	N/A	Superresolution Imaging Reveals the Spatial Organization of CD81 Microdomains in Regulating Membrane Signaling on Jurkat T Cell Microvilli
基于先天适应性的早期运动训练的共享与独特适应	Sadler, D. G.	PDF	N/A	Shared and distinct adaptations to early-life exercise training based on inborn fitness
饮食中一糖和二糖含量的耐受曲线决定了小鼠的体重增加、肠道微生物群组成和认知能力。	Bartochowski, P.	PDF	N/A	Hormetic curve of dietary mono- and disaccharide content determines weight gain, gut microbiota composition and cognitive ability in mice
AIRE的高分辨率转录组影响：致病变体p.Arg257Ter、p.Cys311Tyr和多基因风险变体p.Arg471Cys的影响	Berger, A. H.	PDF	N/A	High-Resolution Transcriptional Impact of AIRE: Effects of Pathogenic Variants p.Arg257Ter, p.Cys311Tyr, and Polygenic Risk Variant p.Arg471Cys
在埃希氏大肠杆菌中设计合成途径以生产(+)-短杆菌肽A和B	Sandoval Hurtado, C. P.	PDF	N/A	Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in Escherichia coli
利用合成血清标志物在体内监测转录	Watanabe, S.	PDF	N/A	Monitoring in vivo transcription with synthetic serum markers
铁饥饿促使绿藻中的第二个LHCⅠ四聚体结合到光系统Ⅰ上。	Liu, H. W.	PDF	N/A	Fe starvation induces a second LHCI tetramer to photosystem I in green algae
不同家族间的传感器和辅助NLRs的共转移扩展了被子植物间的免疫受体功能	Du, X.	PDF	N/A	Interfamily co-transfer of sensor and helper NLRs extends immune receptor functionality between angiosperms
冷胁迫通过CBF依赖的调控途径重塑了桉树杂交种的木材形成。	Bachir, I. H.	PDF	N/A	Cold stress involves CBF dependent regulatory pathway to remodel wood formation in Eucalyptus gunnii hybrids.
简和迷你简，一个用于马铃薯功能基因组学的模型系统	Xin, H.	PDF	N/A	Jan and mini-Jan, a model system for potato functional genomics
胞质中的果糖——蔗糖生物合成调控中被低估的角色？	Giesbrecht, O.	PDF	N/A	Cytosolic fructose - an underestimated player in the regulation of the sucrose biosynthesis?
细胞增殖与细胞分裂方向的协调控制了拟南芥的径向花柱发育。	Jamil, I.	PDF	N/A	The coordination of cell proliferation and cell-division orientation controls Arabidopsis radial style development
Lr14a介导的细胞质钙内流调控小麦对叶锈病的气孔免疫	Yue, L.	PDF	N/A	Cytoplasmic calcium influx mediated by Lr14a regulates stomatal immunity against leaf rust in wheat
FaDAM3和FaDAM4是调控栽培草莓季节二态性的候选基因。	David, S.	PDF	N/A	FaDAM3 and FaDAM4 are candidate genes for the regulation of seasonal dimorphism in cultivated strawberry
双重红色过量（TREx）：一种简单而新颖的数字颜色指数，能够对绿叶以及富含花青素的作物进行无创实时健康评估。	Agarwal, A.	PDF	N/A	Two-fold Red Excess (TREx): A simple and novel digital color index that enables non-invasive real-time health assessment of green-leaved as well as anthocyanin-rich crops
烟草TA29和芝麻GN13启动子均能在转基因芝麻（Sesamum indicum L.）中提供花药特异性的GUS表达。	Debnath, A. J.	PDF	N/A	Both tobacco TA29 and sesame GN13 promoters provide anther-specific GUS expression in transgenic sesame (Sesamum indicum L.)
叶用莴苣中，细胞分裂素有效促进芽再生的浓度与种皮颜色之间的关系	Kimura, M.	PDF	N/A	Relationship between concentration of cytokinin for efficient shoot regeneration and seed coat color in leaf lettuce
恶性疟原虫（在马来西亚消灭前的临床分离株）的内在繁殖率变异	Stewart, L. B.	PDF	N/A	Intrinsic multiplication rate variation of Plasmodium falciparum (in clinical isolates prior to elimination in Malaysia
在马来西亚消除之前，临床分离的恶性疟原虫的内在繁殖率变化	Stewart, L. B.	PDF	N/A	Intrinsic multiplication rate variation of Plasmodium falciparum in clinical isolates prior to elimination in Malaysia
与环境敏感性和炎症相关生物标志物关系相关的肠道微生物组关键分类群	Takasugi, S.	PDF	N/A	Key taxa of the gut microbiome associated with the relationship between environmental sensitivity and inflammation-related biomarkers
利用环境DNA（eDNA）针对陆地脊椎动物的研究：趋势、展望及采样考虑	Newton, J. P.	PDF	N/A	Targeting terrestrial vertebrates with eDNA: Trends, perspectives, and considerations for sampling
PlateletBase：一个综合性的血小板研究与疾病洞察知识库	Luo, H.	PDF	N/A	PlateletBase: A Comprehensive Knowledgebase for Platelet Research and Disease Insights
将生物分割数据集合理地进行FAIR存储	Ho, E. M. L.	PDF	N/A	Depositing biological segmentation datasets FAIRly
FSTL3是一种预后不良的生物标志物，并与卵巢癌中的免疫治疗抵抗相关。	Chauvin, M.	PDF	N/A	FSTL3 is a biomarker of poor prognosis and is associated with immunotherapy resistance in ovarian cancer.
近红外实时无损监测糖分积累的研究表明，单个浆果的成熟速度比在标准异步样本上先前记录的要快两倍。	Tavernier, F.	PDF	N/A	Near-infrared real time non-destructive monitoring of sugar accumulation reveals that single berries ripen two times faster than previously documented on standard asynchronous samples
胡椒属植物Piper fimbriulatum中显著多样的生物碱骨架	Damiani, T.	PDF	N/A	Remarkable diversity of alkaloid scaffolds in Piper fimbriulatum
生长素拮抗剂PEO-IAA和生长素运输抑制剂NPA对藓类植物（Physcomitrium patens (Hedw.) Mitt.）配子体发育的影响	Robinson, S. R.	PDF	N/A	Effects of an auxin antagonist, PEO-IAA, and an auxin transport inhibitor, NPA, on gametophore development in Physcomitrium patens (Hedw.) Mitt.
植物诱导的转录可塑性在广食性和专食性植食者之间存在差异。	Wu, J.	PDF	N/A	Plant-induced transcriptional plasticity diverges between generalist and specialist herbivores
印度白纹伊蚊种群中的击倒抗性（kdr）突变：携带V1016G、F1534C和F1534L kdr等位基因的单倍型之间缺乏重组	Kaur, T.	PDF	N/A	Knockdown-resistance (kdr) mutations in Indian Aedes aegypti populations: lack of recombination among haplotypes bearing V1016G, F1534C, and F1534L kdr alleles
白质分数各向异性寿命规范模型：应用于早期精神病	Cirstian, R.	PDF	N/A	Lifespan Normative Models of White Matter Fractional Anisotropy: Applications to Early Psychosis
下一代测序揭示了在早发性结直肠癌中出现新型生殖系变异的模式。	VANDE PERRE, P.	PDF	N/A	Next generation sequencing identifies a pattern of novel germline variants in early-onset colorectal cancer
保持轨道：胶原蛋白纤维的排列方向对高剪切力下的血栓形成有显著影响。	Melnikova, J. A.	PDF	N/A	Staying on track: collagen fibers orientation strongly affects thrombi formation at high shear
Pex3促进过氧化物酶体与过氧化物酶体以及过氧化物酶体与脂滴接触点的形成。	Amado, L.	PDF	N/A	Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites
一种针对牛肝菌（Boletus edulis）的单倍体型解析染色体参考基因组	Brejon Lamartiniere, E.	PDF	N/A	A haplotype-resolved chromosomal reference genome for the porcini mushroom Boletus edulis
强迫症患者在认知负荷下的心率动态与抗氧化能力	Portnova, G. V.	PDF	N/A	The heart rate dynamics and antioxidant capacity under cognitive load in Obsessive-Compulsive disorder
驱动蛋白KIF3AC循环内吞的整合素，以极化粘附形成朝向前缘	Rockenbach, J. A.	PDF	N/A	The kinesin KIF3AC recycles endocytosed integrin to polarize adhesion formation towards the leading edge
温度敏感的皮层凝聚调节三细胞连接处的机械响应	Zheng, Q.-h.	PDF	N/A	Temperature-sensitive cortical condensation modulates mechano-response at Tricellular Junctions
Bicoid-核小体竞争设定了一个由基因组复制所限制的转录浓度阈值。	Degen, E. A.	PDF	N/A	Bicoid-nucleosome competition sets a concentration threshold for transcription constrained by genome replication
不同的调控元件程序引导小鼠性腺发育过程中性别特异的支持细胞分化。	Stevant, I.	PDF	N/A	Divergent regulatory element programs steer sex-specific supporting cell differentiation along mouse gonadal development
单细胞转录组学分析显示，经过X射线照射的果蝇翅盘细胞存在异质性，这种异质性与细胞周期状态和细胞位置相关。	Cruz, J.	PDF	N/A	Single cell transcriptomics of X-ray irradiated Drosophila wing discs reveals heterogeneity related to cell-cycle status and cell location
使用Jax-EPBD高效生成高吞吐量的DNA呼吸特征	Inan, T. T.	PDF	N/A	Efficient High-Throughput DNA Breathing Features Generation Using Jax-EPBD
inVAE：用于生成多元单细胞参考图的条件不变表示学习	Aliee, H.	PDF	N/A	inVAE: Conditionally invariant representation learning for generating multivariate single-cell reference maps
根-孔隙相互作用，被低估的驱动因素，影响根际结构和根鞘发育	Geers-Lucas, M.	PDF	N/A	Root-pore interactions, the underestimated driver for rhizosphere structure and rhizosheath development
用于细胞内肽组和小蛋白部分质谱分析的通用工具集	Kote, S.	PDF	N/A	Universal toolset for mass spectrometric analysis of intracellular peptidome and small protein fraction
传感器运动驱动主动神经元细胞自动机中的突发注意力和可扩展性	Kvalsund, M.-K.	PDF	N/A	Sensor Movement Drives Emergent Attention and Scalability in Active Neural Cellular Automata
小鼠上丘中的Loom反应依赖于感觉运动背景	Zucca, S.	PDF	N/A	Loom response in mouse superior colliculus depends on sensorimotor context
创伤性脑损伤的临床前模型中，伽马频段脑电功能网络的拓扑结构、成本和动力学的改变	Tsikonofilos, K.	PDF	N/A	Alterations in topology, cost and dynamics of gamma-band EEG functional networks in a preclinical model of traumatic brain injury
Msp1 和 Pex19-Pex3 协同作用，以实现 Pex15 在过氧化物酶体中的正确定位。	Matsumoto, S.	PDF	N/A	Msp1 and Pex19-Pex3 cooperate to achieve correct localization of Pex15 to peroxisomes
GRASP55通过控制溶酶体酶在高尔基体中的分类，保护了溶酶体的正常功能。	Nuechel, J.	PDF	N/A	GRASP55 Safeguards Proper Lysosome Function by Controlling Sorting of Lysosomal Enzymes at the Golgi
肠道成纤维细胞异质性：统一RNA测序研究并引入共识驱动的命名法	Glisovic, N.	PDF	N/A	Intestinal fibroblast heterogeneity: unifying RNA-seq studies and introducing consensus-driven nomenclature
量化H9c2大鼠心肌细胞视黄酸分化的形态学、功能和生化特征	York, N. S.	PDF	N/A	Quantification of morphological, functional, and biochemical features of H9c2 rat cardiomyoblast retinoic acid differentiation
雷帕霉素诱导的自噬增强了脂质分解并改善了大西洋鲑鱼细胞的脂毒性。	Phadwal, K.	PDF	N/A	Rapamycin induced autophagy enhances lipid breakdown and ameliorates lipotoxicity in Atlantic salmon cells.
5' HOXD基因在手关节滑膜成纤维细胞中差异性调控基因表达	Mirrahimi, M.	PDF	N/A	5' HOXD Genes Differentially Regulate Gene Expression of Synovial Fibroblasts in Hand Joints
Survivin调节硬度诱导的血管平滑肌细胞迁移	Mousso, T.	PDF	N/A	Survivin modulates stiffness-induced vascular smooth muscle cell motility
肝脂稳态中线粒体-脂滴相互作用的空间解析重塑。	Kang, S. W. S.	PDF	N/A	Spatially resolved rewiring of mitochondria-lipid droplet interactions in hepatic lipid homeostasis.
NFAT2通过利用表观遗传景观的差异，同时驱动Orai3的转录和蛋白质降解。	Raju, S.	PDF	N/A	NFAT2 drives both Orai3 transcription and protein degradation by harnessing the differences in epigenetic landscape
冷冻电镜揭示PMEL淀粉样蛋白的致病机制与色素播散综合征相关	Yanagisawa, H.	PDF	N/A	Cryo-EM of PMEL Amyloids Reveals Pathogenic Mechanism of Pigment Dispersion Syndrome
内体成熟是由通过Na+/H+交换体和pH依赖的Rab GTPase循环进行的向内质子信号传导所调控的。	Lee, Y.	PDF	N/A	Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling
周细胞将物理创伤信号转化为快速的血管反应。	Gelashvili, Z.	PDF	N/A	Perivascular macrophages convert physical wound signals into rapid vascular responses
使用快速扩增多重-荧光原位杂交（RAM-FISH）进行空间mRNA定位	Banerjee, T. D.	PDF	N/A	Spatial mRNA profiling using Rapid Amplified Multiplexed-FISH (RAM-FISH)
海绵-海草共生关系中的互惠营养益处	Cardini, U.	PDF	N/A	Reciprocal nutritional benefits in a sponge-seagrass association
树枝年龄 2.0：调整不同分类群之间可食性差异的树枝年龄数据，以追踪有蹄类动物在不同地点和时间上的啃食情况	Waller, D. M.	PDF	N/A	Twig Age 2.0: Adjusting twig age data for differences in palatability among taxa to track ungulate browsing over sites and time
Notch信号通路在肺部的多纤毛细胞中稳定了运动纤毛的长度。	Guha, A.	PDF	N/A	Notch signaling stabilizes lengths of motile cilia in multiciliated cells in the lung
致癌性RAS诱导了一种独特的非经典自噬形式，该形式由P38-ULK1-PI4KB轴介导。	Ge, L.	PDF	N/A	Oncogenic RAS Induces a Distinctive Form of Non-Canonical Autophagy Mediated by the P38-ULK1-PI4KB Axis
APOBEC3B N端和C端结构域之间的调控相互作用	Braza, K.	PDF	N/A	Regulatory interactions between APOBEC3B N- and C-terminal domains
选择晶体衍射数据的有效且可靠的指标	Fu, Z.	PDF	N/A	Effective and Reliable Metrics to Select Crystal Diffraction Data
RNA池中的序列基序动态变化	Harth-Kitzerow, J.	PDF	N/A	Sequence motif dynamics in RNA pools
秀丽隐杆线虫肠道细菌负荷的差异表明宿主与微生物之间存在复杂的相互作用。	Boddu, S. S.	PDF	N/A	Variance in C. elegans gut bacterial load suggests complex host-microbe dynamics
多盆地Go-Martini方法用于研究蛋白质的构象转变和环境相互作用	Yang, S.	PDF	N/A	Multiple-Basin Go-Martini for Investigating Conformational Transitions and Environmental Interactions of Proteins
GSK3β驱动的ABLIM1与心肌肌联蛋白相互作用调节的分子机制	Sun, B.	PDF	N/A	Molecular mechanisms of GSK3β-driven modulation of ABLIM1 and titin interactions in cardiac muscle
基准测试人体步态模拟的预测能力。	Afschrift, M.	PDF	N/A	Benchmarking the predictive capability of human gait simulations.
使用设计表面活性剂蛋白质组装分层多相凝聚物	Guan, M.	PDF	N/A	Assembly of Hierarchical Multiphase Condensates Using Designer Surfactant Proteins
一个研究多组分肌动蛋白动力学的广义理论框架	Nandi, M.	PDF	N/A	A generalized theoretical framework to investigate multicomponent actin dynamics
一个研究多组分肌动蛋白动力学的广义理论框架	Nandi, M.	PDF	N/A	A generalized theoretical framework to investigate multicomponent actin dynamics
基于Mango成像系统的TO1-B染料的截短和“双头”衍生物，具有增强的亮度和选择性以及显著的红移	Svetlova, J. I.	PDF	N/A	Truncated and "double-headed" derivatives of TO1-B dye for Mango-based imaging systems with increased brightness and selectivity and large Stocks shift
使用DNA条形码库发现结合FKBP12和新靶点的分子胶	Michaud, G. A.	PDF	N/A	Discovery of molecular glues that bind FKBP12 and novel targets using DNA-barcoded libraries
使用DNA条形码库发现结合FKBP12和新靶点的分子胶	Zandi, T. A.	PDF	N/A	Discovery of molecular glues that bind FKBP12 and novel targets using DNA-barcoded libraries
戈谢病中血液和红细胞的计算机生物物理学和流变学	Chai, Z.	PDF	N/A	In silico biophysics and rheology of blood and red blood cells in Gaucher Disease
转录抑制因子BCL11A的Z0结构域的解决方案结构揭示了蛋白质结合锌指的序列特性	Harris, R. E.	PDF	N/A	Solution structure of the Z0 domain from transcription repressor BCL11A sheds light on the sequence properties of protein-binding zinc-fingers
MuSkeMo：开源软件，用于在Blender中构建、分析和可视化人体和动物的肌肉骨骼模型及其运动	van Bijlert, P. A.	PDF	N/A	MuSkeMo: Open-source software to construct, analyze, and visualize human and animal musculoskeletal models and movements in Blender
分子拥挤抑制机械应力驱动的DNA链分离	Desai, P. R.	PDF	N/A	Molecular Crowding Suppresses Mechanical Stress-Driven DNA Strand Separation
KAT6/KAT7的催化抑制增强了Menin抑制剂在MLL白血病中的疗效，并克服了原发性和获得性耐药性。	Gordon, S. J.	PDF	N/A	Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia
脑膜瘤中的肿瘤相关巨噬细胞：作为独立的不良预后因素，其影响超越了T细胞的益处	Lotsch, C.	PDF	N/A	Tumor-Associated Macrophages in Meningiomas: An Independent Prognostic Factor for Poor Survival Outperforming the Benefits of T cells
一种NAMPT抑制剂减少了一种针对5-磷酸核糖-1-焦磷酸结合环的抗体对NAMPT的捕获：这是NAMPT占有率测定的合理依据	Shomali, M.	PDF	N/A	An NAMPT Inhibitor Decreases NAMPT Capture by an Antibody Directed against the 5-Phosphoribosyl-1-Pyrophosphate-Binding Loop: A Rational for an NAMPT Occupancy Assay
STAT1促进PD-L1激活及淋巴管平滑肌瘤病中的肿瘤生长	Olatoke, T.	PDF	N/A	STAT1 Promotes PD-L1 Activation and Tumor Growth in Lymphangioleiomyomatosis
前列腺癌相关成纤维细胞的分泌组分析以识别潜在的治疗靶点	Abikar, A.	PDF	N/A	Secretome analysis of cancer-associated fibroblasts from prostate cancer to identify potential therapeutic targets
AKR1C介导了HER-2阳性胃癌细胞系对T-Dxd的获得性耐药。	wang, d.	PDF	N/A	AKR1C mediates the acquired resistance to T-Dxd in a HER-2 positive gastric cancer line
精神病前驱期亚群中的显著网络分离与症状特征	Iyer, A.	PDF	N/A	Salience Network Segregation and Symptom Profiles in Psychosis Prodrome Subgroups
E-钙粘蛋白的内吞作用促进了非经典的EGFR:STAT信号传导，从而诱导细胞死亡并抑制异染色质化。	Ramirez-Moreno, M.	PDF	N/A	E-cadherin endocytosis promotes non-canonical EGFR:STAT signalling to induce cell death and inhibit heterochromatinisation
脂质翻转、O抗原屏蔽及水动力学：通过100-200微秒粗粒化模拟揭示的大肠杆菌外膜蛋白特性	Kalenkiewicz, A.	PDF	N/A	Lipid Flipping, O-antigen Shielding, and Water Dynamics Revealed by 100-200 μs Coarse-Grained Simulations of E. coli Outer Membrane Proteins
RNA编码物理信息。	Seim, I.	PDF	N/A	RNA encodes physical information
合理设计19F NMR标记位点以探测蛋白质结构和相互作用	Streit, J. O.	PDF	N/A	Rational design of 19F NMR labelling sites to probe protein structure and interactions
识别中分辨率冷冻电镜密度图中的氨基酸侧链	Mondal, D.	PDF	N/A	Recognizing amino acid sidechains in a medium resolution cryo-electron density map
人类RAD52复合物经历相分离，并促进RAD51前联会丝的捆绑和端到端连接。	Alshareedah, I.	PDF	N/A	The human RAD52 complex undergoes phase separation and facilitates bundling and end-to-end tethering of RAD51 presynaptic filaments
珊瑚珊瑚虫特异性视蛋白采用了一种新颖的氯离子对抗离子用于光谱调谐	Sakai, Y.	PDF	N/A	Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning
对天然结构和化学图谱数据的分析揭示了RNA中的局部稳定性补偿现象。	Cornwell-Arquitt, R. L.	PDF	N/A	Analysis of natural structures and chemical mapping data reveals local stability compensation in RNA
ColBuilder：交联胶原蛋白纤维的灵活结构生成	Monego, D.	PDF	N/A	ColBuilder: Flexible structure generation of crosslinked collagen fibrils
离子液体对泛素稳定性的调控：疏水相互作用的主导作用	Shrivastava, A.	PDF	N/A	Ionic Liquid-Induced Modulation of Ubiquitin Stability: The Dominant Role of Hydrophobic Interactions
急性淋巴细胞白血病中的增强子异质性驱动患者间的差异基因表达	Smith, A. L.	PDF	N/A	Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression between patients
通过细胞外囊泡优先释放的微小RNA与从导管原位癌向浸润性乳腺癌进展相关	Elayapillai, S. P.	PDF	N/A	Preferential Release of microRNAs via Extracellular Vesicles is Associated with Ductal Carcinoma In Situ to Invasive Breast Cancer Progression
METCAM/MUC18在鼻咽癌III型的发展中扮演着肿瘤促进者的角色。	Liu, Y.-C.	PDF	N/A	METCAM/MUC18 plays a tumor promoter role in the development of nasopharyngeal carcinoma type III
纤维状癌的单细胞多组学分析揭示了重构的细胞间通讯模式和独特的脆弱性	Farghli, A. R.	PDF	N/A	Single-cell multi-omic analysis of fibrolamellar carcinoma reveals rewired cell-to-cell communication patterns and unique vulnerabilities
解读与卵巢癌患者不良生存率相关的肿瘤浸润性CD73+调节性γδ T细胞生态系统	LAFONT, V.	PDF	N/A	Deciphering the tumor-infiltrating CD73+ regulatory gammadelta T cell ecosystem associated with poor survival of patients with ovarian cancer
FAK通过调节糖酵解和线粒体功能，通过肌动蛋白-肌球蛋白收缩性调控胶质母细胞瘤干细胞的能量代谢。	Masalmeh, R. H. A.	PDF	N/A	FAK modulates glioblastoma stem cell energetics via actomyosin contractility: regulation of glycolysis and mitochondrial function
现代化组织病理学分析：一种用于肠道微菌落存活实验数字图像分析的全自动工作流程	Baikalov, A.	PDF	N/A	Modernizing histopathological analysis: a fully automated workflow for the digital image analysis of the intestinal microcolony survival assay
DNMT/G9a复合物抑制揭示了急性髓性白血病的表观遗传脆弱性并诱导干扰素反应	Schoenefeld, A.	PDF	N/A	DNMT/G9a Complex Inhibition Uncovers Epigenetic Vulnerabilities and Induces IFN-Response in Acute Myeloid Leukemia
增强子长链非编码RNA LOC730338限制了对抗淋巴瘤细胞的先天免疫反应，抑制了依赖ADAR2的替代转录。	Cascione, L.	PDF	N/A	Enhancer lncRNA LOC730338 limits the innate immune response against lymphoma cells, inhibiting ADAR2-dependent alternative transcription.
细胞优先调控细胞质量密度	Fu, J.	PDF	N/A	Cells Prioritize the Regulation of Cell Mass Density
通过图神经网络和迁移学习实现对蛋白质分子性质的精确预测	Wozniak, S.	PDF	N/A	Accurate Predictions of Molecular Properties of Proteins via Graph Neural Networks and Transfer Learning
OASL通过cGAS-STING途径对胃癌中OXA诱导的免疫原性细胞死亡的影响	Sun, D.	PDF	N/A	Effect of OASL on OXA-induced immunogenic cell death in gastric cancer via cGAS-STING pathway
三阴性乳腺癌的患者源性异种移植模型能够实现化疗反应的解析和预测。	Lei, J. T.	PDF	N/A	Patient-Derived Xenografts of Triple-Negative Breast Cancer Enable Deconvolution and Prediction of Chemotherapy Responses
CoREST复合物的抑制通过改变RNA剪接促进新抗原表达并增强肿瘤免疫	Fisher, R. J.	PDF	N/A	CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity
儿童期单侧半球切除术后患者的空间和物体注意能力	Robert, S.	PDF	N/A	Space- and object-based attention in patientswith a single hemisphere following childhood resection
得克萨斯州中部海岸科帕诺湾、阿拉善湾和红鱼湾底栖有孔虫（玫瑰红染色）的分布情况	Barrera, A.	PDF	N/A	DISTRIBUTION OF LIVING (ROSE BENGAL STAINED) BENTHIC FORAMINIFERA IN COPANO, ARANSAS, AND REDFISH BAYS, CENTRAL TEXAS COAST
变体集蒸馏	Christ, R.	PDF	N/A	Variant Set Distillation
从心脏组织基质或血浆中分离的小细胞外囊泡显示出与年龄相关的货物变化，这些变化有助于慢性心血管疾病的发展。	Ronan, G.	PDF	N/A	Small Extracellular Vesicles Isolated from Cardiac Tissue Matrix or Plasma Display Distinct Aging-Related Changes in Cargo Contributing to Chronic Cardiovascular Disease
记忆编码的相位重置动力学	Colyer, R. A.	PDF	N/A	Phase reset dynamics of memory encoding
通路热力学分析假设谷氨酸代谢的变化是调节免疫反应的关键因素	Malla, S.	PDF	N/A	Pathway Thermodynamic Analysis Postulates Change in Glutamate Metabolism as a Key Factor in Modulating Immune Responses
CD4共受体调控性别特异性NK细胞对急性弓形虫感染的反应。	Roy, T.	PDF	N/A	CD4 Co-Receptor Regulates Sex-Specific NK Cell Responses to Acute Toxoplasma gondii Infection.
种子传播中断限制了热带森林的再生。	Fricke, E. C.	PDF	N/A	Seed dispersal disruption limits tropical forest regrowth
在小鼠眼中，全反式视黄酸受光和多巴胺的调节。	Talwar, S.	PDF	N/A	Modulation of all-trans retinoic acid by light and dopamine in the murine eye
皮肤成纤维细胞稳态的改变有助于愈合结果	Huang, Y.	PDF	N/A	Alteration of skin fibroblast steady state contributes to healing outcomes
从三色堇（Viola odorata）中计算预测的环肽（cyclotides）作为肺炎链球菌（Streptococcus pneumoniae）神经氨酸酶潜在抑制剂的研究	Sankar, S.	PDF	N/A	Computational prediction of cyclotides from Viola odorata as potential inhibitors against the neuraminidase of Streptococcus pneumoniae
全球多组学分析显示，渐进式跑步机运动对啮齿动物的exerkines有影响。	Taha, H. B.	PDF	N/A	Global multi-omics analysis of exerkines in progressive treadmill-exercised rodents
任务因素影响在牵张反射中的时间位移	Torell, F.	PDF	N/A	Temporal shift in task factor influence across the stretch reflex
通过超局部温度测量法测量的麻醉动物大脑与体温之间的关系	Osypov, A. A.	PDF	N/A	Relationship between Brain and Body Temperature in Anesthetized Animals Measured by Ultralocal Thermometry
丘脑网状核亚群的生物物理建模及其对网络动力学的差异化贡献	Litvak, P. F.	PDF	N/A	Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to network dynamics
皮质类器官中的目标导向学习	Robbins, A. S.	PDF	N/A	Goal-Directed Learning in Cortical Organoids
在小鼠体感皮层中的感知选择与运动信号	Minamisawa, G.	PDF	N/A	Perceptual choice and motor signals in mouse somatosensory cortex
行为和遗传标志物，用于识别芬太尼摄入量增加的易感性。	Keady, J.	PDF	N/A	Behavioral and genetic markers of susceptibility to escalate fentanyl intake.
多模态单细胞分析揭示了人类药物难治性癫痫中神经元衰老的分子标志物。	Ge, Q.	PDF	N/A	Multimodal single-cell analyses reveal molecular markers of neuronal senescence in human drug-resistant epilepsy
在戒断初期阻断下丘脑分泌素受体1可减少未来的可卡因需求	Espana, R.	PDF	N/A	Hypocretin receptor 1 blockade early in abstinence reduces future demand for cocaine
使用EMG驱动的肌肉骨骼模型开发实时神经控制器	Thomas, J. B.	PDF	N/A	Development of a real-time neural controller using an EMG-driven musculoskeletal model
一种用于线性表位疫苗分析的快速方法揭示了意外的表位标签免疫原性	Browne-Cole, K.	PDF	N/A	A rapid approach for linear epitope vaccine profiling reveals unexpected epitope tag immunogenicity
虚拟临床试验揭示了靶向肿瘤相关巨噬细胞和小胶质细胞治疗胶质母细胞瘤的显著临床潜力	Mongeon, B.	PDF	N/A	Virtual clinical trial reveals significant clinical potential of targeting tumour-associated macrophages and microglia to treat glioblastoma
通过遗传亲本分配和PIT标记验证大西洋鲑（Salmo Salar）鳞片读数	Utne, K. R.	PDF	N/A	Validating Atlantic salmon (Salmo Salar) scale reading by genetic parent assignment and PIT-tagging
性尺寸二态性与哺乳动物中的雄激素反应数量相关，但仅限于小型体型的物种。	Ghione, C. R.	PDF	N/A	Sexual size dimorphism correlates with the number of androgen response in mammals, but only in small-bodied species
发育不完全的羽枝增加了早期羽毛的形态多样性	Zhang, Y.	PDF	N/A	Developmentally Incomplete Barb Rami Increased the Morphological Diversity of Early Feathers
博物馆保护见解：揭示贾巴托小丑蛙（Atelopus ignescens）的灭绝因素	Guerra, M. A.	PDF	N/A	Museum insights for conservation: Unraveling the Extinction Factors in the Jambato Harlequin Frog, Atelopus ignescens
兰花、天蛾与达尔文再探：天蛾传粉如何推动了旧大陆和新大陆安格科斯类植物的物种形成	Farminhao, J. N.	PDF	N/A	Orchids, hawkmoths and Darwin revisited: How adaptation to pollination by hawkmoths spurred the speciation of Old and New World angraecoids
使用红外摄像机追踪棉铃虫（鳞翅目：夜蛾科）在性信息素诱捕器周围的飞行行为	Duplais, C.	PDF	N/A	Tracking Helicoverpa zea (Lepidoptera: Noctuidae) flight behavior with infrared camera around pheromone trap
老鼠在追求食物和休闲时遵循相同的理性原则。	Logue, R. S.	PDF	N/A	Rats pursue food and leisure following the same rational principles
玻璃化与快速复温在药理学和生物医学研究中对精准切割的肝脏切片的应用	Ramesh, S.	PDF	N/A	Vitrification and rapid rewarming of precision-cut liver slices for pharmacological and biomedical research
使用卷积神经网络进行挤出式生物打印的自主控制	Kelly, D.	PDF	N/A	Autonomous control of extrusion bioprinting using convolutional neural networks
利用配对的生物力学-组织学有限元分析（FEA）建模模拟大型机械活性培养系统（BigMACS），以推导力学生物学设计关系。	Schoenborn, S.	PDF	N/A	Simulating big mechanically-active culture systems (BigMACS) using paired biomechanics-histology FEA modelling to derive mechanobiology design relationships.
基于环境电离质谱成像的分子数字孪生技术的发展及其在肿瘤外科实时应用中的潜力	ZIrem, Y.	PDF	N/A	Development of Molecular Digital Twins Based on Ambient Ionization Mass Spectrometry Imaging for Real-Time Application in Oncological Surgery
皮肤等效物中再生的真皮间充质细胞的异质性调节屏障功能和弹性。	Kimura, S.	PDF	N/A	The heterogeneity of dermal mesenchymal cells reproduced in skin equivalents regulate barrier function and elasticity.
一种用于类器官成熟自适应智能调制的AI-半机械人系统	Liu, R.	PDF	N/A	An AI-Cyborg System for Adaptive Intelligent Modulation of Organoid Maturation
OrthoHMM：利用隐马尔可夫模型改进直系同源群的推断	Steenwyk, J. L.	PDF	N/A	OrthoHMM: Improved Inference of Ortholog Groups using Hidden Markov Models
卷积-长短期记忆网络方法用于时间热点捕捞区（CATCH）：一种用于渔业捕捞概率密度时空预测的AI驱动模型	Agmata, A.	PDF	N/A	Convolutional-LSTM Approach for Temporal Catch Hotspots (CATCH): An AI-Driven Model for Spatiotemporal Forecasting of Fisheries Catch Probability Densities
模拟类似PPR疾病的扩散以改进监测	Apolloni, A.	PDF	N/A	Simulating the diffusion of PPR-like disease to improve surveillanc
scPDA：基于液滴的单细胞数据中蛋白质表达的去噪	Zhu, O.	PDF	N/A	scPDA: Denoising Protein Expression in Droplet-Based Single-Cell Data
跨多个实验室整合定性和定量数据以进行模型校准	Rodriguez, R. B.	PDF	N/A	Integrating qualitative and quantitative data across multiple labs for model calibration
SPE-CZE-MS 技术能够定量检测磷酸化肽的仄摩尔浓度。	Serrano, L. R.	PDF	N/A	SPE-CZE-MS quantifies zeptomole concentrations ofphosphorylated peptides
混合神经微分方程用于模拟生物学中未知机制和状态	Whipple, B.	PDF	N/A	Hybrid Neural Differential Equations to Model Unknown Mechanisms and States in Biology
在儿童皮质切除术后视觉皮层的类别选择性的横断面和纵向变化	Liu, T. T.	PDF	N/A	Cross-sectional and longitudinal changes in category-selectivity in visual cortex following pediatric cortical resection
运动诱导的AMPK信号转导的差异性转录输出改善了轴突再生和功能恢复	Behera, S.	PDF	N/A	Exercise-induced differential transcriptional output of AMPK signalling improves axon regeneration and functional recovery
抗体通过配体模拟和变构干扰来破坏细菌的粘附。	Hvorecny, K. L.	PDF	N/A	Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference
使用旁系同源基因进行系统发育推断可以减轻长枝吸引效应的影响。	Smith, M. L.	PDF	N/A	Using paralogs for phylogenetic inference mitigates the effects of long-branch attraction
一种无需标记的基于纳米孔的阻抗传感器，用于十分钟内检测SARS-CoV-2	Meng, Z.	PDF	N/A	A Label-free Nanowell-based Impedance Sensor for Ten-minute SARS-CoV-2 Detection
解读结直肠癌与肝细胞相互作用：一种用于探索肝肿瘤微环境中代谢串扰的多组学平台	Nelson, A. B.	PDF	N/A	Deciphering Colorectal Cancer-Hepatocyte Interactions: A Multiomic Platform for Interrogation of Metabolic Crosstalk in the Liver-Tumor Microenvironment
mRNA-1273和NVX-CoV2373 COVID-19疫苗多克隆抗体反应的结构血清学	Bangaru, S.	PDF	N/A	Structural serology of polyclonal antibody responses to mRNA-1273 and NVX-CoV2373 COVID-19 vaccines
悬浮含菌模拟呼吸道液滴的蒸发与致病性：在不同相对湿度和蒸发阶段的研究	Agharkar, A. N.	PDF	N/A	Evaporation and pathogenesis of levitated bacteria-laden surrogate respiratory fluid droplets: At different relative humidity and evaporation stages
万古霉素耐药的肠球菌通过占据特定的营养和代谢物定义的肠道生态位，在抗生素处理后的肠道中定植。	King, O. G.	PDF	N/A	Vancomycin-resistant Enterococcus colonise the antibiotic-treated intestine by occupying distinct nutrient- and metabolite-defined intestinal niches
生境过滤而非微生物群起源控制土壤中微生物群移植的结果	Causevic, S.	PDF	N/A	Habitat filtering but not microbiota origin controls microbiome transplant outcomes in soil
探索共生大肠杆菌在体外调节抗生素抗性沙门氏菌海德堡株转录组变化的研究	Kariyawasam, S.	PDF	N/A	Exploring Transcriptomic Changes in Antibiotic-Resistant Salmonella Heidelberg Modulated by Commensal Escherichia coli in Vitro
金黄色葡萄球菌COL：一种非典型的MRSA模型菌株，表现出缓慢生长和抗生素耐受性	Stevens, C. E.	PDF	N/A	Staphylococcus aureus COL: An Atypical Model Strain of MRSA that Exhibits Slow Growth and Antibiotic Tolerance
沙门氏菌鼠伤寒杆菌通过操控突触融合蛋白7在宿主细胞的内吞-溶酶体运输中导航	Vij, R.	PDF	N/A	Salmonella Typhimurium Manipulates Syntaxin 7 to Navigate Endo-Lysosomal Trafficking in Host Cells
一种新型膜应激反应，通过ClpP蛋白酶靶向DnaA起始因子来阻止染色体复制	Saxena, R.	PDF	N/A	A novel membrane stress-response that blocks chromosomal replication by targeting the DnaA initiator via the ClpP protease
MetaBiome：一种多尺度模型，整合基于代理的建模和代谢网络，揭示黏膜微生物群落中的空间调控	Aminian-Dehkordi, J.	PDF	N/A	MetaBiome: A Multiscale Model Integrating Agent-Based Modeling and Metabolic Networks Reveals Spatial Regulation in Mucosal Microbial Communities
一种新型抗真菌相互作用测试方法：评估白色念珠菌临床分离株中的协同作用与拮抗作用。	Lundvik, H.	PDF	N/A	A Novel Method for Testing Antifungal Interactions: Assessing Synergy and Antagonism in Candida albicans Clinical Isolates.
微生物群落中的移民概率和持续时间	Curtis, T. P.	PDF	N/A	The probability and duration of immigration in microbial communities
维持伴侣蛋白Spy中的甲硫氨酸残基处于还原状态对于周质蛋白质稳态至关重要。	Loiseau, L.	PDF	N/A	Maintaining the methionine residues of the chaperone Spy in a reduced state is crucial for periplasmic proteostasis.
增强产量与温和纯化HIV用于病毒体成熟过程的冷冻电镜断层分析。	Preece, B.	PDF	N/A	Enhanced Yield and Gentle Purification of HIV for Cryo-Electron Tomography Analysis of Virion Maturation.
spotPCR：一种利用独特分子标识符快速高效地索引单个模板分子的方法	Limberis, J. D.	PDF	N/A	spotPCR: A Rapid and Efficient Approach for Indexing Individual Template Molecules using Unique Molecular Identifiers
增强RNA递送：NeoLNP转染试剂的实用见解	Chen, X.	PDF	N/A	Enhancing RNA Delivery: Practical Insights into NeoLNP Transfection Reagent
多聚磷酸盐作为超级增强子复合物的新型调控因子：相分离的破坏与基因表达	Yang, Z.	PDF	N/A	Polyphosphate as a Novel Regulator of Super-Enhancer Complexes: Disruption of Phase Separation and Gene Expression
Sir2蛋白对于rDNA在静止状态下特有的凝聚三维染色质结构是必需的。	Cucinotta, C.	PDF	N/A	Sir2 is required for the quiescence-specific condensed three-dimensional chromatin structure of rDNA
年龄相关的DNA甲基化变化模式	Chen, K. Y.	PDF	N/A	Age-Related Patterns of DNA Methylation Changes
基于在二聚体界面引入二硫键和B因子分析，对提高ZHD101热稳定性的合理分子设计	DING, W.	PDF	N/A	Rational molecular design for improved ZHD101 thermal stability based on the introduction of disulfide bonds at the dimer interface and B-factor analysis
林蛙在免疫基因表达和能量储存表型上的组成性差异与冬季环境共同变化	Vaziri, G. J.	PDF	N/A	Constitutive differences in immune gene expression and energy storage phenotypes co-vary with winter environment in wood frogs
红点豆娘（Hetaerina spp.）非生态物种形成的时空动态	Patterson, C.	PDF	N/A	Spatiotemporal dynamics of non-ecological speciation in rubyspot damselflies (Hetaerina spp.)
哺乳动物热休克蛋白A4家族直向同源物Hsc70Cb在果蝇D. melanogaster的精子发生过程中对两个阶段是必需的。	Houston, B. J.	PDF	N/A	Mammalian heat shock protein A4 family ortholog Hsc70Cb is required for two phases of spermatogenesis in D. melanogaster
长读基因组学揭示了一种双核真菌中广泛的核特异性进化和等位基因特异性表达	Tam, R.	PDF	N/A	Long-read genomics reveal extensive nuclear-specific evolution and allele-specific expression in a dikaryotic fungus
糖皮质激素受体的多聚化途径	Estebanez-Perpina, E.	PDF	N/A	The multimerization pathway of the glucocorticoid receptor
通过自上而下蛋白质组学对跨物种心室肌球蛋白轻链1中S-谷胱甘肽化的深入表征	Chapman, E. A.	PDF	N/A	In-depth Characterization of S-Glutathionylation in Ventricular Myosin Light Chain 1 Across Species by Top-Down Proteomics
结核分枝杆菌EsxG·EsxH（TB9.8·TB10.4）肽作为亚单位疫苗，用于增强卡介苗（BCG）在肺结核实验模型中的接种效果。	Martinez-Olivares, C. E.	PDF	N/A	Mycobacterial EsxG·EsxH (TB9.8·TB10.4) peptides as a subunit vaccine to booster BCG vaccination in an experimental model of pulmonary Tuberculosis
超稳定且多功能的微卫星FoxP3集合	Leng, F.	PDF	N/A	Ultrastable and Versatile FoxP3 Ensembles on Microsatellites
一种独特的自体荧光分布模式标志着植物细胞壁的酶解破坏	Hossein Khani, S.	PDF	N/A	A Distinct Autofluorescence Distribution Pattern Marks Enzymatic Deconstruction of Plant Cell Wall
钙调蛋白结合是钙介导的TRPA1脱敏作用所必需的。	Sanders, J. H.	PDF	N/A	Calmodulin binding is required for calcium mediated TRPA1 desensitization
山梨酸通过I类HDACs的非经典活性诱导赖氨酸山梨酰化，以调控炎症基因的表达	Sin, Y.-C.	PDF	N/A	Sorbate Induces Lysine Sorbylation Through Non-Canonical Activities of Class I HDACs to Regulate the Expression of Inflammation Genes
人类酸感应离子通道1a的构象可塑性	Cahill, J.	PDF	N/A	Conformational plasticity of human acid-sensing ion channel 1a
利用高吞吐量细菌表达分泌型scFv-ompY融合蛋白，对tilvestamab（一种抗AXL功能阻断抗体）的抗原结合位点进行映射。	Christakou, E.	PDF	N/A	Paratope mapping of tilvestamab, an anti-AXL function blocking antibody, using high-throughput bacterial expression of secreted scFv-ompY fusion proteins
使用INDEGRA进行无偏差转录组比较的高精度RNA完整性定义	Cleynen, A.	PDF	N/A	High-Accuracy RNA Integrity Definition for Unbiased Transcriptome Comparisons with INDEGRA
多尺度单细胞评估特发性肺纤维化中的纤维化生态位	Liu, B.	PDF	N/A	Multiscale single-cell assessment of the fibrotic niche in idiopathic pulmonary fibrosis
设计具有氨酰-tRNA合成酶活性的核酶	Gan, G.	PDF	N/A	Engineering a ribozyme with aminoacyl-tRNA synthetase activity
多组学分析与牛（Bos taurus）基因组规模代谢重构，以优化培养肉的生产	Lee, J.	PDF	N/A	Multi-omics analysis and genome-scale metabolic reconstruction of cattle Bos taurus for optimal production of cultured meat
在两种密切相关的鹿鼠物种（Peromyscus maniculatus和P. leucopus）中的听力研究	Joseph, L.	PDF	N/A	Hearing in Two Closely Related Peromyscus Species (Peromyscus maniculatus and P. leucopus)
动态细胞命运可塑性和组织整合推动功能性滑膜关节再生	Blumenkrantz, M.	PDF	N/A	Dynamic cell fate plasticity and tissue integration drive functional synovial joint regeneration
人类卵母细胞中的线粒体DNA突变会受到频率依赖性选择的影响，但不会随年龄增长而增加。	Arbeithuber, B.	PDF	N/A	Mitochondrial DNA mutations in human oocytes undergo frequency-dependent selection but do not increase with age
用于蓝藻细胞分割与分类的机器学习模型	Huffine, C. A.	PDF	N/A	Machine Learning Models for Segmentation and Classification of Cyanobacterial Cells
夜行性斗牛蚁（Myrmecia midas）在没有成功的情况下运行路线的复杂性	deeti, s.	PDF	N/A	Intricacies of running a route without success in night-active bull ants (Myrmecia midas)
丹麦猪群中重组A(H1N1)流感病毒的迅速激增及其人畜共患潜力	Ryt-Hansen, P.	PDF	N/A	Rapid Surge of Reassortant A(H1N1) Influenza Viruses in Danish Swine and their Zoonotic Potential
分类学的时间机器	Davis-Richardson, A.	PDF	N/A	A Time Machine for Taxonomy
通过对外周血的跨疾病建模，识别出可预测阿尔茨海默病的2型糖尿病生物标志物。	Ball, B. K.	PDF	N/A	Cross-disease modeling of peripheral blood identifies biomarkers of type 2 diabetes predictive of Alzheimer's disease
对强光暴露引起的打喷嚏反应：一个光敏感性打喷嚏者的案例研究	Bickerstaff, L.	PDF	N/A	Sneezing in response to bright light exposure: A case study in a photic sneezer
频率跟随反应揭示的与年龄相关的神经相位锁定能力下降，对包络和时间精细结构的锁定：可能是影响言语可懂度的耳蜗突触病变的一个潜在标志。	Ponsot, E.	PDF	N/A	Age-related decline in neural phase-locking to envelope and temporal fine structure revealed by frequency following responses: A potential signature of cochlear synaptopathy impairing speech intelligibility
食品来源化合物延长冷冻人乳的保质期	Silpe, J. E.	PDF	N/A	Food-Derived Compounds Extend the Shelf-Life of Frozen Human Milk
使用新型Klhl14-Cre小鼠系选择性靶向皮质脊髓神经元的一个特定亚群，使得从发育到成熟阶段的分子和解剖学研究成为可能。	Lustig, J.	PDF	N/A	Selective Targeting of a Defined Subpopulation of Corticospinal Neurons using a Novel Klhl14-Cre Mouse Line Enables Molecular and Anatomical Investigations through Development into Maturity
你在说什么？人类大脑中言语主题的表征	Boncz, A.	PDF	N/A	What are you talking about? Representation of the Topic of Speech in the Human Brain
记忆印迹的解构揭示了在学习过程中招募的不同神经元集群	Pouget, C.	PDF	N/A	Deconstruction of a memory engram reveals distinct ensembles recruited at learning
认知努力与奖励。任务时间和多巴胺能及胆碱能基质参与的功能性成像。	Orsini, C.	PDF	N/A	Cognitive effort and reward. Functional imaging of time on task and the involvement of dopaminergic and cholinergic substrates
从人类到蠕虫，所有的核糖体RNA和45S间隔区都充满了生物体特有的基序，这些基序的其他副本主要存在于大量神经系统基因中，其中包括许多与人类疾病相关的基因。	Rigoutsos, I.	PDF	N/A	All ribosomal RNAs and 45S spacers from humans to worms are packed with organism-specific motifs whose other copies are found predominantly in numerous nervous system genes including many associated with human disorders
利用单核多组学技术对癫痫中伴有少突胶质细胞增生的轻度皮质发育不良的细胞类型进行映射	Galvao, I. C.	PDF	N/A	Cell type mapping of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy using single-nucleus multiomics
有蹄类动物的个性和人类盾牌效应共同导致了长距离迁徙的减少。	Cotterill, G.	PDF	N/A	Ungulate personality and the human shield contribute to long-distance migration loss
# BioRxiv 2024-12-11 Papers

标题	作者	PDF链接	代码仓库	Title
基于逻辑的糖尿病肾病中炎症性巨噬细胞与肾小球内皮细胞相互作用的建模	Patidar, K.	PDF	N/A	Logic-Based Modeling of Inflammatory Macrophage Crosstalk with Glomerular Endothelial Cells in Diabetic Kidney Disease
皮质微电路中不确定性感知的预测误差	Wilmes, K. A.	PDF	N/A	Uncertainty-modulated prediction errors in cortical microcircuits
丹尼索瓦人、尼安德特人和现代人类中的MUC19基因：反复基因渗入与自然选择的进化历程	Villanea, F. A.	PDF	N/A	The MUC19 gene in Denisovans, Neanderthals, and Modern Humans: An Evolutionary History of Recurrent Introgression and Natural Selection
暴食通过调节嗅觉风味表征来促进食欲	Lo, H.	PDF	N/A	Binge Feeding Promotes Appetite via Modulating Olfactory Flavor Representation
细菌肌动蛋白同源物家族形成了一个三股螺旋管状结构。	Bergeron, J.	PDF	N/A	A family of bacterial actin homologues forms a 3-stranded tubular structure
自适应编码解释了阿尔茨海默病、自闭症谱系障碍和创伤后应激障碍中，海马体大小与记忆功能之间看似矛盾的关系。	Stocco, A.	PDF	N/A	Adaptive Coding Explains the Paradoxical Relationship between hippocampus size and memory function in Alzheimer's Disease, Autism Spectrum Disorder, and PTSD
量化分层肌肉相互作用对运动功能的多样化贡献	O'Reilly, D.	PDF	N/A	Quantifying the diverse contributions of hierarchical muscle interactions to motor function
ganon2：最新且可扩展的宏基因组分析工具	Piro, V. C.	PDF	N/A	ganon2: up-to-date and scalable metagenomics analysis
基于记忆的偏好的主动构建与被动响应	Nicholas, J.	PDF	N/A	Proactive and reactive construction of memory-based preferences
在贝叶斯推理过程中，随着信念精度的提高，神经变异性会逐渐压缩。	Skowron, A.	PDF	N/A	Neural variability compresses with increasing belief precision during Bayesian inference
深海热液虾Rimicaris exoculata基因表达的潮汐调控	Zhang, H.	PDF	N/A	Circatidal control of gene expression in the deep-sea hot vent shrimp Rimicaris leurokolos
通过学习生成来掌握细胞语言	Chen, Y.	PDF	N/A	Toward mastering the cell language by learning to generate
通过胶质细胞转分化实现成年神经发生的中枢神经系统损伤范式	Casas-Tinto, S.	PDF	N/A	Adult Neurogenesis through Glial Transdifferentiation in a CNS Injury Paradigm
感觉输入匹配视觉工作记忆引导内部优先级	Koevoet, D.	PDF	N/A	Sensory Input Matching Visual Working Memory Guides Internal Prioritization
K2R：用于从测序数据集中高效提取读取的着色德布鲁因图实现	Vandamme, L.	PDF	N/A	K2R: Tinted de Bruijn Graphs implementation for efficient read extraction from sequencing datasets
标准设定对意识神经测量的建构效度构成了威胁。	Fahrenfort, J. J.	PDF	N/A	Criterion placement threatens the construct validity of neural measures of consciousness
一项全基因组关联研究指出，果蝇（Drosophila melanogaster）的滞育相关寿命延长和繁殖力与嗅觉系统有关。	Easwaran, S.	PDF	N/A	A genome-wide association study implicates the olfactory system in Drosophila melanogaster diapause-associated lifespan extension and fecundity
葡萄藤感染Shiraz病后，病毒多样性及韧皮部转录变化的研究	Onetto, C. A.	PDF	N/A	Viral diversity and phloem transcriptional changes in Grapevine Shiraz disease infected vines
利用多细胞模拟识别上皮单层屈曲的竞争机制	Brown, P. J.	PDF	N/A	Competing mechanisms for the buckling of an epithelial monolayer identified using multicellular simulation
功能冗余和非肌动蛋白依赖的定位在酵母Saccharomyces cerevisiae中的原肌球蛋白同工型	Dhar, A.	PDF	N/A	Functional redundancy and formin-independent localization of tropomyosin isoforms in Saccharomyces cerevisiae
组蛋白是受细胞应激调控的外泌体膜蛋白。	Singh, B.	PDF	N/A	Histones are exosome membrane proteins regulated by cell stress
一个综合的单核和空间转录组图谱揭示了人类海马体的分子景观	Thompson, J. R.	PDF	N/A	An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus
在小鼠模型中实现人工假肢	Hayatou, Z.	PDF	N/A	Embodiment of an artificial limb in the mouse model
通过提高高粱和甘蔗中Rubisco含量，适应大气变化并增加C4光合作用的生产力	Salesse-Smith, C. E.	PDF	N/A	Adapting C4 photosynthesis to atmospheric change and increasing productivity by elevating Rubisco content in Sorghum and Sugarcane
宿主编码的DNA甲基转移酶能够修饰侵入噬菌体的表观基因组和宿主特异性。	Takahashi, M.	PDF	N/A	Host-encoded DNA methyltransferases modify the epigenome and host tropism of invading phages
PROTAC诱导的蛋白质结构动力学在靶向蛋白质降解中的作用	Wu, K. Y.	PDF	N/A	PROTAC-induced Protein Structural Dynamics in Targeted Protein Degradation
瞬时域间相互作用调节Huntingtin外显子1的单体结构集合及其自组装	Mohanty, P.	PDF	N/A	Transient interdomain interactions modulate the monomeric structural ensemble and self-assembly of Huntingtin Exon 1
两个分离的世界：论生命科学与生物医学研究中的影响力偏好	Gu, Z.	PDF	N/A	Two Separated Worlds: on the Preference of Influence in Life Science and Biomedical Research
金盏花：一个基于机器学习的斑马鱼姿态追踪网络应用	Teicher, G.	PDF	N/A	Marigold: A machine learning-based web app for zebrafish pose tracking
凝胶中荧光蛋白的直接观察：免疫印迹的快速、成本效益高且定量的替代方法	Sanial, M.	PDF	N/A	Direct observation of fluorescent proteins in gels: a rapid, cost-efficient and quantitative alternative to immunoblotting
生物入侵过程中与适应性进化相关的花期表型特征的纬度渐变	Akbar, M.	PDF	N/A	Latitudinal clines in the phenology of floral display associated with adaptive evolution during a biological invasion
通过PHORCE揭示了噬菌体扩增速率的极端多样性以及噬菌体与抗生素相互作用的复杂性。	Mulla, Y.	PDF	N/A	Extreme diversity of phage amplification rates and phage-antibiotic interactions revealed by PHORCE
Syntaxin-2 协调内溶酶体运输，以平衡巨噬细胞中的吞噬摄取和吞噬溶酶体清除。	Samanta, S.	PDF	N/A	Syntaxin-2 coordinates endolysosomal trafficking to balance phagocytic uptake and phagolysosomal clearance in macrophages
全球海洋中硅藻多样性和丰度的模式与驱动因素	Pierella Karlusich, J. J.	PDF	N/A	Patterns and drivers of diatom diversity and abundance in the global ocean
山兔（Lepus timidus）染色体水平参考基因组组装	Fekete, Z.	PDF	N/A	Chromosome-level reference genome assembly for the mountain hare (Lepus timidus)
微生物群落在进行水平基因转移时出现替代稳定状态	Hong, J.	PDF	N/A	Emergence of alternative stable states in microbial communities undergoing horizontal gene transfer
表征漂移作为持续记忆存储的结果	Devalle, F.	PDF	N/A	Representational drift as the consequence of ongoing memory storage
使用高度多样化的条形码库定量小鼠感染中鼠伤寒沙门氏菌种群动力学	Hotinger, J. A.	PDF	N/A	Quantification of Salmonella enterica serovar Typhimurium Population Dynamics in Murine Infection Using a Highly Diverse Barcoded Library
气候变化下地方性种群的爆发性昆虫暴发	Brush, M.	PDF	N/A	Eruptive insect outbreaks from endemic populations under climate change
学习进度表与教学的共同演化，不仅促进了知识的累积，还催生了一种教师创新综合症。	Maisonneuve, L.	PDF	N/A	The coevolution of learning schedules and teaching enhances cumulative knowledge and drives a teacher-innovator syndrome
CrypToth：通过混合溶剂分子动力学模拟和拓扑数据分析进行隐秘口袋检测	Koseki, J.	PDF	N/A	CrypToth: Cryptic pocket detection through mixed-solvent molecular dynamics simulations based topological data analysis
艰难梭菌的定植并非由胆盐介导，而是在体外模型中利用了脯氨酸的斯蒂克兰发酵作用。	Huang, X.	PDF	N/A	Clostridioides difficile colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an in vitro model
TwinEco：生态学中动态数据驱动数字孪生的统一框架	Khan, T.	PDF	N/A	TwinEco: A Unified Framework for Dynamic Data-Driven Digital Twins in Ecology
章鱼可以利用气味烟羽来寻找食物。	Weertman, W. L.	PDF	N/A	Octopus can use odor plumes to find food
多效性在从现有遗传变异适应过程中增强了并行选择特征	Lai, W.-Y.	PDF	N/A	Pleiotropy increases parallel selection signatures during adaptation from standing genetic variation
葡萄糖激酶活性调控位于外周的β细胞亚群，这些细胞主导胰岛钙离子振荡。	Jin, E.	PDF	N/A	Glucokinase activity controls peripherally-located subpopulations of β-cells that lead islet Ca2+ oscillations
通过转录凝聚体对基因的急性激活影响染色质域中的非目标基因	Bohra, D.	PDF	N/A	Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain
通过实验进化揭示果蝇攻击性的进化反馈	Girardeau, A. R.	PDF	N/A	Evolutionary feedbacks for Drosophila aggression revealed through experimental evolution
斑马鱼视觉系统中对猎物刺激的双眼整合	Tian, G.	PDF	N/A	Binocular integration of prey stimuli in the zebrafish visual system
对拟南芥中影响叶片毛状体发育和表皮金属积累的基因进行全基因组关联筛选	Bezvoda, R.	PDF	N/A	A genome-wide association screen for genes affecting leaf trichome development and epidermal metal accumulation in Arabidopsis
管道奥运会：针对DNA甲基化测序数据计算工作流程的可续性基准测试，以实验金标准为对照	Lin, Y.-Y.	PDF	N/A	Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard
哺乳动物视网膜双极细胞：兔视网膜形态学鉴定与系统分类，并附比较视角	Famiglietti, E. V.	PDF	N/A	Mammalian Retinal Bipolar Cells: Morphological Identification and Systematic Classification in Rabbit Retina, with a Comparative Perspective
丰度测量揭示了人类肠道微生物群中裂解与溶原之间的平衡。	Lopez, J. A.	PDF	N/A	Abundance measurements reveal the balance between lysis and lysogeny in the human gut microbiome
LongTrack：基于长读长宏基因组学的粪便微生物群移植后细菌菌株及其基因组变化的精准追踪	Fan, Y.	PDF	N/A	LongTrack: long read metagenomics-based precise tracking of bacterial strains and their genomic changes after fecal microbiota transplantation
使用单细胞和单核测序技术进行可扩展电路图谱绘制的高复杂度条码狂犬病病毒	Shin, D.	PDF	N/A	High-Complexity Barcoded Rabies Virus for Scalable Circuit Mapping Using Single-Cell and Single-Nucleus Sequencing
光化学分析突触和突触外NMDA受体分子多样性	Sicard, A.	PDF	N/A	Optochemical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites
通过通信子空间在大规模新皮层模型中进行认知网络交互	Pereira-Obilinovic, U.	PDF	N/A	Cognitive network interactions through communication subspaces in large-scale models of the neocortex
纹状体胆碱能中间神经元的同步激活引发局部血清素释放。	Matityahu, L.	PDF	N/A	Synchronous activation of striatal cholinergic interneurons induces local serotonin release
AnnSQL：一个基于Python SQL的包，用于在笔记本电脑上进行大规模单细胞基因组学分析	Pavan, K.	PDF	N/A	AnnSQL: A Python SQL-based package for large-scale single-cell genomics analysis on a laptop
资源环境塑造了人类阴道微生物群的组成和稳定性。	Kamiya, T.	PDF	N/A	Resource landscape shapes the composition and stability of the human vaginal microbiota
大肠杆菌K12中tRNA修饰缺陷的协同效应。	Bacusmo, J. M.	PDF	N/A	Synergistic effects of tRNA modification defects in Escherichia coli K12.
通过成像质谱流式技术对细胞外基质进行表型分析，揭示了与过敏性气道炎症相关的不同细胞外基质环境。	Parkinson, J. E.	PDF	N/A	Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation.
通过机器学习分析免疫单细胞RNA测序数据，揭示免疫检查点疗法反应的预测基因和细胞特征	Pinhasi, A.	PDF	N/A	Uncovering Predictive Gene and Cellular Signatures for Checkpoint Immunotherapy Response through Machine Learning Analysis of Immune Single-Cell RNA-seq Data
有害突变可能有助于性染色体之间重组抑制的进化。	Jay, P.	PDF	N/A	Deleterious mutations can contribute to the evolution of recombination suppression between sex chromosomes
老年对黑猩猩使用石器工具的参与度和效率的影响是多变的。	Howard-Spink, E.	PDF	N/A	Old age variably impacts chimpanzee engagement and efficiency in stone tool use
肽胶束递送以在细胞内形成稳定的相互作用枢纽	Tu, W.	PDF	N/A	Delivery of Peptide Coacervates to Form Stable Interaction Hubs In Cells
人类诱导多能干细胞（iPSCs）中染色体12三体性激增的起源	Narozna, M.	PDF	N/A	Origin of Chromosome 12 Trisomy Surge in Human Induced Pluripotent Stem Cells (iPSCs)
使用12-6 Lennard-Jones势能模型模拟银(I)离子与蛋白质的相互作用：一种自下而上的参数化方法	Manciocchi, L.	PDF	N/A	Modelling the interaction between silver(I) ion and proteins with the 12-6 Lennard-Jones potential: a bottom-up parameterization approach
癌基因SLC35F2是一种高特异性的转运蛋白，专门负责转运微量营养素喹啉和喹喔啉。	Burtnyak, L.	PDF	N/A	The oncogene SLC35F2 is a high-specificity transporter for the micronutrients queuine and queuosine
多尺度建模展示了细胞-细胞外基质（ECM）相互作用如何影响ECM纤维排列和细胞脱离。	Arellano-Tinto, J.	PDF	N/A	Multiscale modelling shows how cell-ECM interactions impact ECM fibre alignment and cell detachment
自愿行动能够增强感官预测，并促进对相关感官刺激的神经处理。	Ody, E.	PDF	N/A	Voluntary action sharpens sensory prediction and facilitates neural processing of contingent sensory stimuli
CECR2溴结构域展现出对乙酰化组蛋白与非组蛋白配体不同的结合模式。	Phillips, M.	PDF	N/A	The CECR2 bromodomain displays distinct binding modes to select for acetylated histone proteins versus non-histone ligands.
利用计算工具来理解雷公藤内酯-XPB相互作用	Gorrie, D.	PDF	N/A	Leveraging computational tools to understand the triptolide-XPB interaction
膜焦磷酸酶对H+运输的快速动力学：直接耦合机制的证据	Anashkin, V. A.	PDF	N/A	Rapid kinetics of H+ transport by membrane pyrophosphatase: evidence for a direct-coupling mechanism
DiscoEPG：一个用于昆虫电穿透图（EPG）信号特征分析的Python包	Dinh, Q. D.	PDF	N/A	DiscoEPG: A Python package for characterization of insect electrical penetration graph (EPG) signals
一个关于多稳态的决策理论模型：感知转换作为内部行动	Safavi, S.	PDF	N/A	A decision-theoretic model of multistability: perceptual switches as internal actions
SegCSR：基于脑带分段实现皮质表面重建的弱监督方法	Zheng, H.	PDF	N/A	SegCSR: Weakly-Supervised Cortical Surfaces Reconstruction from Brain Ribbon Segmentations
抗肥胖化合物，司美格鲁肽和利拉鲁肽，不会改变人类和小鼠POMC+神经元的比例。	Jörgensen, S. K. M.	PDF	N/A	Anti-obesity compounds, Semaglutide and LiPR, do not change the proportion of human and mouse POMC+ neurons
在回文性风湿病中滑膜炎发作的棘轮模型	Chakraborty, S.	PDF	N/A	The Ratchet Model of Synovial Flares in Palindromic Rheumatism
N1-甲基假尿苷mRNA修饰通过防止Prkra介导的全局翻译抑制，增强了基因过表达的效率和特异性。	Lu, T.	PDF	N/A	N1-methylpseudouridine mRNA modification enhances efficiency and specificity of gene overexpression by preventing Prkra-mediated global translation repression
最近邻树算法与哈达玛变换在系统发育推断中的进展与应用	Alvarez Gonzalez, E.	PDF	N/A	Advances and applications of the closest-tree algorithm and Hadamard conjugation in phylogenetic inference
EXTRA-seq：一种基因组整合的扩展型大规模并行报告基因分析方法，用于量化增强子-启动子通信	Kribelbauer-Swietek, J. F.	PDF	N/A	EXTRA-seq: a genome-integrated extended massively parallel reporter assay to quantify enhancer-promoter communication
生成式人工智能辅助的虚拟筛选流程，用于通用且高效的药物再利用	Pham, P.	PDF	N/A	Generative AI-assisted Virtual Screening Pipeline for Generalizable and Efficient Drug Repurposing
信标重建攻击：利用汇总统计数据在基因组数据共享信标中重建基因组	Saleem, K.	PDF	N/A	Beacon Reconstruction Attack: Reconstruction of genomes in genomic data-sharing beacons using summary statistics
将自然语言处理与基因组分析相结合，能够实现对细菌表型的精确预测。	Gomez-Perez, D.	PDF	N/A	Integrating natural language processing and genome analysis enables accurate bacterial phenotype prediction
L2G：将语言模型重新用于基因组学任务	Cheng, W.	PDF	N/A	L2G: Repurposing Language Models for Genomics Tasks
Kolmogorov-Arnold网络用于基因组任务	Cherednichenko, O.	PDF	N/A	Kolmogorov-Arnold Networks for Genomic Tasks
成对图编辑距离表征了构建方法对泛基因组图的影响	Dubois, S.	PDF	N/A	Pairwise graph edit distance characterizes the impact of the construction method on pangenome graphs
整合单细胞RNA测序和空间转录组学揭示了在股骨髋臼撞击症和骨关节炎患者的人类髋关节滑膜中，巨噬细胞与成纤维细胞之间的不同相互作用。	Kulzhanova, G.	PDF	N/A	Integrative scRNA-seq and spatial transcriptomics uncovers distinct macrophage-fibroblast cross-talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis
塞米利琴 - 一种被不公正忽视的绿色生物膜与真菌地衣之间的共生系统	Vondrak, J.	PDF	N/A	Semilichen - an unjustly neglected symbiotic system between green biofilms and true lichens
肌肉长度根据收缩类型的不同，对复发性抑制和激活后抑制的调节作用也有所不同。	Colard, J.	PDF	N/A	Muscle length modulates recurrent inhibition and post-activation depression differently according to contraction type
言语掩蔽对人类对连续言语的皮层下反应的影响	Polonenko, M. J.	PDF	N/A	The effect of speech masking on the human subcortical response to continuous speech
比较糖皮质激素对人MR（Ile-180）和人MR单倍型（Ile180Val）的转录激活作用	Katsu, Y.	PDF	N/A	Comparison of Transcriptional Activation by Corticosteroids of Human MR (Ile-180) and Human MR Haplotype (Ile180Val)
深度预测编码网络部分捕捉到了人类视觉皮层中短期时间适应的神经特征。	Brands, A. M.	PDF	N/A	Deep predictive coding networks partly capture neural signatures of short-term temporal adaptation in human visual cortex
海马神经元的轴突和树突中，不稳定铁的储存和运输是由溶酶体介导的。	Kittilukkana, A.	PDF	N/A	Storage and transport of labile iron is mediated by lysosomes in axons and dendrites of hippocampal neurons
LC3相关胞吞作用促进小胶质细胞对外源Tau聚集体的内化和降解	CHIDAMBARAM, H.	PDF	N/A	LC3-associated endocytosis facilitates extracellular Tau aggregate internalization and degradation in microglia
介导视交叉上核昼夜节律同步的功能性连接组	Nikhil, K. L.	PDF	N/A	The Functional Connectome Mediating Circadian Synchrony in the Suprachiasmatic Nucleus
血管性痴呆患者脑室周围白质单核RNA测序	Diaz-Perez, S.	PDF	N/A	Single-nucleus RNA sequencing of human periventricular white matter in vascular dementia
FAM53C/DYRK1A轴调控细胞周期G1/S期的转换	Hammond, T.	PDF	N/A	THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
Tet2和Tet3在视网膜发育过程中调控细胞命运的确定和分化事件。	Heilman, S.	PDF	N/A	tet2 and tet3 regulate cell fate specification and differentiation events during retinal development
在发育和进化的时间尺度上基因共表达的灵活性	Fischer, E. K.	PDF	N/A	Flexibility in Gene Coexpression at Developmental and Evolutionary Timescales
在马拉维湖慈鲷中，与营养级相关的肠道长度分化是在性冲突下演化而来的。	Carmona Baez, A.	PDF	N/A	Trophic level associated gut length divergence evolved under sexual conflict in Lake Malawi cichlids
识别群体采样的亲代-子代三联体中的因果基因型-表型关系	Tang, Y.	PDF	N/A	Identifying causal genotype-phenotype relationships for population-sampled parent-child trios
追踪植物卤化酶的逐步达尔文进化过程	Kim, C. Y.	PDF	N/A	Tracing the stepwise Darwinian evolution of a plant halogenase
星相位：全面相位感知药物基因组学双倍体型分析工具，适用于长读长测序数据	Holt, J. M.	PDF	N/A	StarPhase: Comprehensive Phase-Aware Pharmacogenomic Diplotyper for Long-Read Sequencing Data
GEMS：一种通过稳健数据过滤和语言模型整合进行蛋白质-配体结合亲和力预测的通用图神经网络框架	Graber, D.	PDF	N/A	GEMS: A Generalizable GNN Framework For Protein-Ligand Binding Affinity Prediction Through Robust Data Filtering and Language Model Integration
LSD1去甲基化酶抑制可预防小鼠和猪模型中心肌纤维化，无论是缺血性还是先天性疾病。	ARNAUD, D.	PDF	N/A	LSD1 demethylase inhibition prevents cardiac fibrosis in both ischemic and congenital diseases in mice and pig models
在连续耕作下的作物比在间歇耕作下的作物表现出较少的可塑性。	Alagarasan, G.	PDF	N/A	Crops under continuous cultivation exhibit less plasticity than those under interrupted cultivation
复杂阿片类药物对与情绪、奖赏和成瘾相关的GABA能脑核中谷氨酸能和胆碱能神经传递的调节作用。	Chittajallu, R.	PDF	N/A	Complex opioid driven modulation of glutamatergic and cholinergic neurotransmission in a GABAergic brain nucleus associated with emotion, reward and addiction.
认知疲劳对基于体力努力的决策影响的神经机制	Dryzer, M.	PDF	N/A	Neural mechanisms underlying the effects of cognitive fatigue on physical effort-based decision-making
默认模式和运动网络促进隐性运动序列的早期学习：一项多模态磁共振波谱和功能磁共振成像研究	Hendrikse, J. J.	PDF	N/A	Default mode and motor networks facilitate early learning of implicit motor sequences: a multimodal MR spectroscopy and fMRI study
表观遗传因子KDM6A的去调控在白色念珠菌介导的伤口愈合延迟过程中起作用。	Ghoshal, A.	PDF	N/A	Deregulation of epigenetic factor, KDM6A, is involved during Candida albicans mediated delayed wound healing
BAZ2依赖的染色质重塑在抑制G4 DNA结构及其相关基因组不稳定性中的作用	Vandeuren, A. L.	PDF	N/A	The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability
HP1结合在局部形成了一个对抗转录激活的屏障，并且在染色质解凝过程中持续存在。	Weinmann, R.	PDF	N/A	HP1 binding creates a local barrier against transcription activation and persists during chromatin decondensation
解决控制出生后血管生长和比例的设计原则	Pichardo, D.	PDF	N/A	Resolving the design principles that control postnatal vascular growth and scaling
H3.1K27M诱导的TSK/TONSL-H3.1通路失调导致基因组不稳定性	Yuan, W.	PDF	N/A	H3.1K27M-induced misregulation of the TSK/TONSL-H3.1 pathway causes genomic instability
酵母（Saccharomyces cerevisiae）减数分裂所需的组蛋白H3尾部修饰	Prichard, A.	PDF	N/A	Histone H3 tail modifications required for meiosis in Saccharomyces cerevisiae
在鹅膏菌（Podospora anserina）中，性繁殖受到连续的转录组波动的调控。	Bidard, F.	PDF	N/A	Sexual reproduction is controlled by successive transcriptomic waves in Podospora anserina
Inkube：一种集神经元培养、电生理学和流体交换于一体的综合解决方案	Maurer, B.	PDF	N/A	Inkube: An all-in-one solution for neuron culturing, electrophysiology, and fluidic exchange
蛋白质语言模型的伪似然性捕捉了体内B细胞选择和进化的特征	van Ginneken, D.	PDF	N/A	Protein language model pseudolikelihoods capture features of in vivo B cell selection and evolution
可解释图学习在多模态单细胞数据整合中的应用	Koca, M. B.	PDF	N/A	Explainable Graph Learning for Multimodal Single-Cell Data Integration
PathOmCLIP：通过局部增强的病理学和单细胞基础模型的对比学习，将肿瘤组织学与空间基因表达相连接	Lee, Y.	PDF	N/A	PathOmCLIP: Connecting tumor histology with spatial gene expression via locally enhanced contrastive learning of Pathology and Single-cell foundation model
单细胞质谱分析揭示了苹果愈伤组织衍生细胞中三萜酸积累的异质性。	Laezza, C.	PDF	N/A	Single-cell mass spectrometry reveals heterogeneous triterpenic acid accumulation in apple callus-derived cells
光合作用和遗传适应性支撑着Cistanthe longiscapa在阿塔卡马沙漠中的韧性	Sandoval-Ibanez, O.	PDF	N/A	Photosynthetic and Genetic Adaptations Underpinning the Resilience of Cistanthe longiscapa in the Atacama Desert
染色体工程揭示了染色体臂特异性端粒长度设定的顺式作用机制，以及植物表型、染色质结构和基因表达的稳健性。	Helia, O.	PDF	N/A	Chromosome engineering points to the cis-acting mechanism of chromosome arm-specific telomere length setting and robustness of plant phenotype, chromatin structure and gene expression
减少与冗余：睡眠期间预测误差的信息处理	Blume, C.	PDF	N/A	Reduced and Redundant: Information Processing of Prediction Errors during Sleep
克隆扩增的IgG抗体分泌细胞在同源和异源感染后优先靶向流感核蛋白。	Agrafiotis, A.	PDF	N/A	Clonally expanded IgG antibody-secreting cells preferentially target influenza nucleoprotein following homologous and heterologous infections
超多样性、生物活性以及相互作用特异性的代谢产物仅在共培养中产生，这表明多样化的竞争者可能促进了木霉菌类真菌的次级代谢。	Franco, M. E. E.	PDF	N/A	Hyperdiverse, bioactive, and interaction-specific metabolites produced only in co-culture suggest diverse competitors may fuel secondary metabolism of xylarialean fungi
受体酪氨酸激酶信号通路的下游分支相互依赖，共同塑造了面部的形态。	Hanne, N.	PDF	N/A	Downstream branches of receptor tyrosine kinase signaling act interdependently to shape the face
植物中异形性染色体的演化	Carey, S. B.	PDF	N/A	The evolution of heteromorphic sex chromosomes in plants
蛋白质热稳定性的广泛差异是由结构变化和细胞环境共同介导的。	Walunjkar, N.	PDF	N/A	Pervasive divergence in protein thermostability is mediated by both structural changes and cellular environments
栉水母和副盒形动物分别独立演化出了复杂且功能多样的电压门控K+通道集合。	Simonson, B. T.	PDF	N/A	Ctenophores and parahoxozoans independently evolved complex and functionally diverse sets of voltage-gated K+ channels
两种不同热液液化工艺废水的毒性和生物降解性对厌氧消化的影响及微氧化的效果	Zhou, M.	PDF	N/A	Toxicity and Biodegradation of Two Different Hydrothermal Liquefaction Process Waters to Anaerobic Digestion and the Effect of Microaeration
利用生成式人工智能学习并改进蛋白质适应性高通量筛选——应用于血脑屏障穿透AAV设计	Soniya, K.	PDF	N/A	Learning from and improving upon high-throughputscreens for protein fitness with Generative AI - Application to BBB-crossing AAV design
PathoFact 2.0：一种综合性的管道，用于在宏基因组中预测抗菌药物抗性基因、毒力因子、毒素和生物合成基因簇。	Sunyer, J. O.	PDF	N/A	PathoFact 2.0: An Integrative Pipeline for Predicting Antimicrobial Resistance Genes, Virulence Factors, Toxins and Biosynthetic Gene Clusters in Metagenomes
通过WAY262611抑制DKK-1可抑制骨肉瘤的转移。	Tal, A.	PDF	N/A	Inhibition of DKK-1 by WAY262611 Inhibits Osteosarcoma Metastasis
Wnt靶标IQGAP3通过破坏Axin1-CK1α相互作用促进Wnt信号传导。	Rahmat, M. B.	PDF	N/A	Wnt target IQGAP3 promotes Wnt signaling via disrupting Axin1-CK1α interaction.
在鹰嘴豆中，性状均值和可塑性具有不同的遗传结构	Alagarasan, G.	PDF	N/A	Distinct genetic architecture for trait mean and plasticity in chickpea
STING激动剂通过驱动单核细胞谱系细胞中的招募和内在I型干扰素反应，以实现最佳的抗肿瘤免疫。	Girard, M.	PDF	N/A	STING agonists drive recruitment and intrinsic type I interferon responses in monocytic lineage cells for optimal anti-tumor immunity
装载真核翻译起始因子的细胞外囊泡促进卵巢癌中的巨噬细胞胆固醇代谢	Mittal, S.	PDF	N/A	Eukaryotic Translation Initiation Factor Loaded Extracellular Vesicles Promotes Macrophage Cholesterol Metabolism in ovarian cancer
与人类大脑功能连接组相关的细胞类型及其在精神疾病中的意义	Nie, P.	PDF	N/A	Cell types associated with human brain functional connectomes and their implications in psychiatric diseases
炎症与DNA损伤的交叉作为自闭症谱系障碍发病机制中的一个新轴	lizarraga, s. B.	PDF	N/A	The intersection of inflammation and DNA damage as a novel axis underlying the pathogenesis of autism spectrum disorders
炎症与DNA损伤的交叉作为自闭症谱系障碍发病机制中的一个新轴	Jhanji, M.	PDF	N/A	The intersection of inflammation and DNA damage as a novel axis underlying the pathogenesis of autism spectrum disorders
在不同实验室间协调巨细胞病毒载量定量方面，仍存在哪些挑战？	Boutolleau, D.	PDF	N/A	What challenges remain in harmonizing cytomegalovirus viral load quantification across laboratories?
开发富含侵袭素的外膜囊泡（OMVs）作为疫苗以控制肠出血性大肠杆菌的肠道携带	Garling, A.	PDF	N/A	Development of intimin-enriched outer membrane vesicles (OMVs) as a vaccine to control intestinal carriage of Enterohemorrhagic Escherichia coli
行走的能量消耗是否限制了更大人类产道的发展？	Stansfield, E.	PDF	N/A	Did Energy Costs of Walking Limit the Evolution of a Larger Human Birth Canal?
鉴定与舞毒蛾滞育相关的差异表达基因和蛋白质：通过转录组和蛋白质组分析揭示滞育机制的见解	Xie, Q.	PDF	N/A	Identification of Differentially Expressed Genes and Proteins Related to Diapause in Lymantria Dispar: Insights for the Mechanism of Diapause from Transcriptome and Proteome Analyses
冬眠测量与解释工具（TOHMIN）用于从冬眠期间的体温波动中量化各种数值。	Otsuka, R.	PDF	N/A	Tools of Hibernation Measurement and Interpretation (TOHMIN) for quantifying various values from body temperature fluctuation during hibernation
类胡萝卜素衍生物信号调控了拟南芥中分生组织的活性，并塑造了茎和根的侧生器官的形成。	Sierra, J.	PDF	N/A	Apocarotenoid signaling regulates meristem activity and shapes shoot and root lateral organ formation in Arabidopsis
多发性硬化症患者的少突胶质细胞表现出一种细胞自主性的免疫激活状态。	Hyvarinen, T.	PDF	N/A	Microglia from patients with multiple sclerosis display a cell-autonomous immune activation state
ATF5依赖的GDF15表达介导麻醉诱导的抗中风神经保护作用	Ju, X.	PDF	N/A	ATF5-Dependent GDF15 Expression Mediates Anesthesia-Induced Neuroprotection Against Stroke
大型MAF转录因子在人类骨骼肌中重新激活进化上休眠的快速糖酵解型IIb肌纤维	Sadaki, S.	PDF	N/A	Large MAF Transcription Factors Reawaken Evolutionarily Dormant Fast-Glycolytic Type IIb Myofibers in Human Skeletal Muscle
一种扩散的、多组织伤口信号启动了全身再生	Breen, C.	PDF	N/A	A spreading, multi-tissue wound signal initiates whole-body regeneration
一个转录因子触发开关决定了水螅表皮细胞的分化身份。	Ferenc, J.	PDF	N/A	A transcription factor toggle switch determines differentiated epidermal cell identities in Hydra
相邻细胞间的直接细胞内囊泡交换	Minakawa, T.	PDF	N/A	Direct Intercellular Vesicle Exchange between Adjacent Cells
将生态位从个体扩展到种群及更广泛的范围	Lu, M.	PDF	N/A	Scaling ecological niches from individuals to populations and beyond
无对齐病毒序列分类	van Zyl, D. J.	PDF	N/A	Alignment Free Viral Sequence Classification
使用200 kV电子冷冻显微镜对哺乳动物细胞进行原位结构分析：对研究基础设施的意义。	Szwedziak, P.	PDF	N/A	In situ structural analysis of mammalian cells using a 200 kV electron cryomicroscope: implications for research infrastructure.
SARS-CoV-2融合肽片段对模型膜作用的脂质特异性	Shekunov, E. V.	PDF	N/A	Lipid specificity of action of SARS-CoV-2 fusion peptide fragments on model membranes
肾动脉功能障碍、压力性利尿受损及盐敏感性增加——库欣综合征小鼠模型中的表现	Costello, H. M.	PDF	N/A	Renal arterial dysfunction, impaired pressure natriuresis and salt-sensitivity in a mouse model of Cushing syndrome
刺激重复对猕猴V1和V4微电路的影响解释了伽马同步增加的现象。	Katsanevaki, C.	PDF	N/A	Stimulus-repetition effects on macaque V1 and V4 microcircuits explain gamma-synchronization increase
活减毒疫苗与腺病毒载体疫苗联合使用可完全保护干扰素γ（IFNγ）敲除小鼠免受肺鼠疫的侵害。	Hendrix, E. K.	PDF	N/A	Combination of live attenuated and adenovirus-based vaccines completely protects interferon gamma (IFNγ) knockout mice against pneumonic plague
从摄入到消化，人类母乳微生物群可培养性新见解及其对免疫调节特性的启示	Le Bras, C.	PDF	N/A	New insights into the cultivability of human milk microbiota from ingestion to digestion and implications for its immunomodulatory properties
触发诱惑：一种比较大鼠由辨别性和条件性刺激引发的趋奖行为的新方法	LeCocq, M. R.	PDF	N/A	Triggered Temptations: A New Procedure to Compare Reward-Seeking Behaviour Induced by Discriminative and Conditioned Stimuli in Rats
植物相关细菌中的化学受体家族优先响应植物信号分子甘油-3-磷酸	Velando, F.	PDF	N/A	Chemoreceptor family in plant-associated bacteria responds preferentially to the plant signal molecule glycerol 3-phosphate
对近乎完整的基因组进行独家编目揭示了人类肠道微生物群的新功能见解	Ma, J.	PDF	N/A	Exclusive cataloging of near-complete genomes unveils novel functional insights into the human gut microbiome
包含克拉霉素、氯法齐明和贝达喹啉的治疗方案在慢性鸟分枝杆菌肺部感染的小鼠模型中比单一疗法更有效。	Rimal, B.	PDF	N/A	Regimen comprising clarithromycin, clofazimine and bedaquiline is more efficacious than monotherapy in a mouse model of chronic Mycobacterium avium lung infection
细菌裂解多糖单加氧酶对昆虫幼虫生长有负面影响。	Baranek, J.	PDF	N/A	Bacterial Lytic Polysaccharide Monooxygenases negatively affect insect larvae growth
两种托斯卡纳病毒在小鼠和细胞培养模型中表现出不同的毒力和复制能力。	Roy, M.	PDF	N/A	Two strains of Toscana virus show different virulence and replication capacity in mice and cell culture models
通过动物肠道内容物的宏转录组测序检测外来生物安全威胁的雀麦花叶病毒及新型烟草花叶病毒	Mahar, J.	PDF	N/A	Detection of exotic biosecurity threat ribgrass mosaic virus and novel tobamoviruses through metatranscriptomic sequencing of animal gut content
使用数字滴定PCR技术计数稀有的沃尔巴克氏体共生体	Njogu, A. K.	PDF	N/A	Counting rare Wolbachia endosymbionts using digital droplet PCR
针对FimH粘附素单克隆抗体可预防尿路致病性大肠杆菌引起的尿路感染。	Lopatto, E. D. B.	PDF	N/A	Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI
金黄色葡萄球菌噬菌体80a颈部结构的分析揭示了DNA、尾部完成蛋白和卷尺蛋白之间的相互作用。	Kizziah, J. L.	PDF	N/A	Structure of the Staphylococcus aureus bacteriophage 80a neck shows the interactions between DNA, tail completion protein and tape measure protein
霍乱弧菌O1 El Tor A1552菌株编码两种功能性的鸟氨酸脂合成酶，并在低磷酸盐和低盐度生长条件下诱导鸟氨酸脂的形成。	Vences-Guzman, M. A.	PDF	N/A	Vibrio cholerae O1 El Tor A1552 encodes two functional ornithine lipid synthases and induces ornithine lipid formation under low phosphate and under low salinity growth conditions.
稳定同位素指纹技术可以直接将肠道微生物与其碳源联系起来，并捕捉到体内由饮食引起的底物转换。	Mordant, A.	PDF	N/A	Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo
铜绿假单胞菌的PrrF sRNAs在体温条件下促进生物膜的形成。	Chourashi, R.	PDF	N/A	The Pseudomonas aeruginosa PrrF sRNAs promote biofilm formation at body temperature
基于CRISPR的人工智能辅助环境生物监测，通过人工智能设计引导RNA	Duran-Vinet, B.	PDF	N/A	CRISPR-based environmental biosurveillance assisted via artificial intelligence design of guide-RNAs
急性感染期间肠道微生物组特征可预测长期新冠	Comba, I. Y.	PDF	N/A	Gut Microbiome Signatures During Acute Infection Predict Long COVID
蛋白质和DNA构象变化有助于Cre重组酶的特异性	Montgomery, J. S.	PDF	N/A	Protein and DNA Conformational Changes Contribute to Specificity of Cre Recombinase
海藻酸盐操控的多功能工具——一种具有多种催化活性的肠道细菌海藻酸盐裂解酶	Tandrup, T.	PDF	N/A	The Swiss Army Knife of Alginate Manipulation - A Gut Bacterium Alginate Lyase with Diverse Catalytic Activities
新型及多样亨尼帕病毒糖蛋白的结构与抗原特性研究	May, A. J.	PDF	N/A	Structural and antigenic characterization of novel and diverse Henipavirus glycoproteins
开发一种新型蛋白质结合剂，抑制α激酶eEF2K	Klupt, K. A.	PDF	N/A	Development of a De Novo Protein Binder that Inhibits the Alpha Kinase eEF2K
通过DNA语言模型解读宏基因组读取中的酶学潜力	R, P.	PDF	N/A	Deciphering enzymatic potential in metagenomic reads through DNA language model
在埃希氏大肠杆菌中设计合成生物路线以生产(+)-短杆菌肽A和B	Sandoval Hurtado, C. P.	PDF	N/A	Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in Escherichia coli
使用合成基因电路编程哺乳动物细胞聚集体的延伸	Courte, J.	PDF	N/A	Programming the elongation of mammalian cell aggregates with synthetic gene circuits
无需校准的场依赖像差估计方法，用于大视场范围内的单分子定位显微镜	Rieger, B.	PDF	N/A	Calibration-free estimation of field dependent aberrations for single molecule localization microscopy across large fields of view
人类血浆代谢环境有利于HIV在原代CD4 T淋巴细胞中的复制。	Chauveau, L.	PDF	N/A	Human plasma metabolic environment favours HIV replication in primary CD4 T lymphocytes
鉴定并确定了大肠杆菌噬菌体YDC107尾部在细菌污染缓冲液中的冷冻电镜结构	Kopylov, M.	PDF	N/A	Identification and cryoEM structure determination of Escherichia phage YDC107 tail found in a bacteria-contaminated buffer
沙门氏菌染色体的演变及其对基因表达和染色体构象的影响	Hu, Y.	PDF	N/A	Evolution of Salmonella Chromosomes and Its Influence on Gene Expression and Chromosomal Conformation
HDAC6介导的FoxO1乙酰化和磷酸化调控牙周炎症反应	Lohner, H.	PDF	N/A	HDAC6-Mediated FoxO1 Acetylation And Phosphorylation Control Periodontal Inflammatory Responses
精确的计算机模拟预测修饰RNA与典型RNA结合蛋白的相互作用，采用{lambda}-动力学方法	Angelo, M.	PDF	N/A	Accurate in silico predictions of modified RNA interactions to a prototypical RNA-binding protein with {lambda}-dynamics
跨膜苯丙氨酸残基对γ-分泌酶介导的Notch-1蛋白水解的影响	Malvankar, S.	PDF	N/A	Effects of transmembrane phenylalanine residues on γ-secretase-mediated Notch-1 proteolysis
PRMT1调控的RNA结合蛋白级联反应的寡聚化促进胰腺导管腺癌的发展	Ru, Y.	PDF	N/A	Oligomerization of PRMT1 Regulated RNA-Binding Protein Cascade Promotes Pancreatic Ductal Adenocarcinoma
通过单分子荧光揭示RNA聚合酶II转录激活中的协同介质招募机制	Zhou, D. H.	PDF	N/A	Mechanisms of synergistic Mediator recruitment in RNA polymerase II transcription activation revealed by single-molecule fluorescence
鉴定来自马来西亚芙蓉市的伊丽莎白金菌临床分离株中的新型前噬菌体和整合接合元件的变体	Zajmi, A.	PDF	N/A	Identification of novel prophages and variants of Integrative and Conjugative Elements in Elizabethkingia anophelis clinical isolates from Seremban, Malaysia
在根癌农杆菌中，ChvG-ChvI通路的激活促进了细胞壁应激下的多种生存策略。	Bouchier, J. M.	PDF	N/A	Activation of the ChvG-ChvI pathway promotes multiple survival strategies during cell wall stress in Agrobacterium tumefaciens
基因流动可以揭示幽灵谱系。	Tricou, T.	PDF	N/A	Gene flow can reveal ghost lineages
碱性磷酸酶家族中的祖先芳基硫酸酯酶相较于现存变体，能够实现更高的催化效率提升。	Eenink, B.	PDF	N/A	Ancestral aryl sulfatases in the alkaline phosphatase family allow for greater increases in catalytic efficiency than extant variants
在斑胸草雀的X区通过慢病毒敲低STEP后，改进了等时脉冲	Norton, P.	PDF	N/A	An improved isochronous pulse after lentiviral knock-down of STEP in Area X of juvenile zebra finches
具有自体和发育相关心脏神经嵴衍生组织的人类心脏自组装体	Kostina, A.	PDF	N/A	Self-organizing human heart assembloids with autologous and developmentally relevant cardiac neural crest-derived tissues
血清素系统的发展和成年期的功能受到GDNF的调控。	Garton, D. R.	PDF	N/A	Serotonin system development and adult function are regulated by GDNF
单次延长应激对行为反应的性别特异性调控：PACAP的作用	Smail, M. A.	PDF	N/A	Sex-Specific Regulation of Behavioral Responses to Single Prolonged Stress: Role of PACAP
绘制人类大脑中的神经肽信号传导图	Ceballos, E. G.	PDF	N/A	Mapping neuropeptide sigaling in the human brain
RegVelo：单细胞基因调控动力学	Wang, W.	PDF	N/A	RegVelo: gene-regulatory-informed dynamics of single cells
适应状态决定了突变对进化种群的影响。	Weh, M. T.	PDF	N/A	The adaptive state determines the impact of mutations on evolving populations
海马体中特定频率的θ状态会根据行为背景调节群体活动。	Masaracchia, L.	PDF	N/A	Frequency-specific theta states in the hippocampus modulate population activity with respect to behavioural context
# BioRxiv 2024-12-10 Papers

标题	作者	PDF链接	代码仓库	Title
一个bHLH相互作用代码控制果蝇肠道中的双向分化和自我更新	Puig-Barbe, A.	PDF	N/A	A bHLH interaction code controls bipotential differentiation and self-renewal in the Drosophila gut
Balbiani小体是在卵母细胞发育早期，由微管调控的Buc分子凝聚形成的。	Kar, S.	PDF	N/A	The Balbiani body is formed by microtubule-controlled molecular condensation of Buc in early oogenesis
E3泛素连接酶DTX3L和去泛素化酶USP28通过相互调节彼此的蛋白水平，精细调控DNA双链修复过程。	Mennerich, D.	PDF	N/A	The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA double strand repair through mutual regulation of their protein levels
整合多个单细胞多组学样本与Smmit	Wan, C.	PDF	N/A	Integrating multiple single-cell multi-omics samples with Smmit
人类TUBA1B短开放阅读框产物通过importin-β调控癌细胞生长	Tao, Y.	PDF	N/A	Human TUBA1B short open reading frame product regulates cancer cell growth via importin-β
评估基础模型在单细胞数据分析中的效用	Liu, T.	PDF	N/A	Evaluating the Utilities of Foundation Models in Single-cell Data Analysis
数据驱动估计中对全脑单变量关联研究可重复性的偏差。	Burns, C. D. G.	PDF	N/A	Bias in data-driven estimates of the reproducibility of univariate brain-wide association studies.
髓系细胞驱动的内皮细胞向周细胞的转分化促进了中风后血脑屏障功能的恢复和大脑的自愈。	Li, T.	PDF	N/A	The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke
静息态7T fMRI中的跨皮层深度多层网络分析	Kotlarz, P.	PDF	N/A	Multilayer Network Analysis across Cortical Depths in Resting-State 7T fMRI
使用来自相同读数的核和叶绿体数据进行亚科进化分析	Witharana, E. P.	PDF	N/A	Subfamily evolution analysis using nuclear and chloroplast data from the same reads
语音特征处理中的神经动力学：证据表明特征从声学到句法处理的逐步进展	Karunathilake, I. M. D.	PDF	N/A	Neural Dynamics of the Processing of Speech Features: Evidence for a Progression of Features from Acoustic to Sentential Processing
NAB2-STAT6驱动了孤立性纤维瘤中依赖EGR1的神经内分泌程序	Hill, C.	PDF	N/A	NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in Solitary Fibrous Tumors
在嵌入三维胶原蛋白基质的人类脂肪基质细胞中，肌腱分化程序被激活。	Horde, M.	PDF	N/A	The tendon differentiation program is activated in human adipose stromal cells embedded in a 3D-collagen matrix
表征相似性调节新奇的神经和行为特征	Becker, S.	PDF	N/A	Representational similarity modulates neural and behavioral signatures of novelty
通过基因丢失实现的大流行副溶血性弧菌波次更替	Yang, C.	PDF	N/A	Pandemic Vibrio parahaemolyticus wave succession by gene loss
地方选择塑造了欧洲玉米地方品种的多样性。	Takou, M.	PDF	N/A	Local selection shaped the diversity of European maize landraces
重新评估阅读障碍中的神经噪声假说：来自脑电图和7T磁共振波谱生物标志的见解	Glica, A.	PDF	N/A	Reevaluating the Neural Noise Hypothesis in Dyslexia: Insights from EEG and 7T MRS Biomarkers
噬菌体编码的Hm-oscar基因在茶小卷蛾（Homona magnanima）中再现了沃尔巴克氏体引发的雄性杀灭现象。	Arai, H.	PDF	N/A	Prophage-encoded Hm-oscar gene recapitulates Wolbachia-induced male killing in the tea tortrix moth Homona magnanima
时间细胞在学习过程的早期就会出现，并且编码超出任务要求的刺激模态。	Bhattacharjee, S.	PDF	N/A	Time cells emerge early in learning and encode stimulus modality past task requirements
运动序列学习引发与mu峰特异性相关的皮层脊髓可塑性	Suresh, T.	PDF	N/A	Motor sequence learning elicits mu peak-specific corticospinal plasticity
Hopfield Kuramoto模型中的脑波动力学	Yao, R.	PDF	N/A	Brain wave dynamics in Hopfield Kuramoto model
基因组位点的功能图谱揭示增强子受其靶基因的限制。	Eder, M.	PDF	N/A	Functional maps of a genomic locus reveal confinement of an enhancer by its target gene.
遗传抑制相互作用在不同遗传背景下高度保守。	Paltenghi, C.	PDF	N/A	Genetic suppression interactions are highly conserved across genetic backgrounds
基于表面的与基于体素的有限元头部模型：应变响应的比较分析	Zhou, Z.	PDF	N/A	Surface-Based vs. Voxel-Based Finite Element Head Models: Comparative Analyses of Strain Responses
在运动规划中，连续效应揭示了高效编码	Wang, T.	PDF	N/A	Sequential Effects in Reaching Reveal Efficient Coding in Motor Planning
Orthrus：迈向进化与功能的RNA基础模型	Fradkin, P.	PDF	N/A	Orthrus: Towards Evolutionary and Functional RNA Foundation Models
单分子实验定位精度与理论定位精度之比取决于传感器，通常大于1。	Brenlla-Lopez, A.	PDF	N/A	The ratio between experimental and theoretical localization precision of single molecules is sensor-dependent and typically larger than one
生物系统适应的累积剂量反应	Gupta, A.	PDF	N/A	Cumulative dose responses for adapting biological systems
重复的香烟烟雾暴露会降低体外培养的人原代肺成纤维细胞的增殖率。	Cannard, E. C.	PDF	N/A	Repeated cigarette smoke exposure attenuates the proliferation rate of primary human lung fibroblasts in vitro
永生化的肠系膜间质细胞——体外干细胞龛	Canella, M.	PDF	N/A	Immortalized Intestinal Telocytes - A Stem Cell Niche In Vitro
CAFE：一个集成式网络应用程序，用于光谱流式细胞术中的高维分析与可视化	Siam, M. H. B.	PDF	N/A	CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry
PqsE作为铜绿假单胞菌特异性LuxR型受体调节因子的演变：来自假单胞菌和伯克霍尔德菌的见解	Mallery, C. P.	PDF	N/A	Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia
东非中晚期石器时代过渡的环境背景：季节性作为关键因素	Fusco, M.	PDF	N/A	The environmental context of the Middle-to-Late Stone Age Transition in eastern Africa: seasonality as a key factor
环境相关剂量的双酚A和S在子宫内暴露会跨代扰乱生殖细胞编程，通过单核多组学得以解决。	Zhao, L.	PDF	N/A	Environmentally-relevant doses of bisphenol A and S exposure in utero disrupt germ cell programming across generations resolved by single nucleus multi-omics
中脑多巴胺神经元活动通过脑-体回路调节脾脏免疫	Gopinath, A.	PDF	N/A	Brain-body circuit by which midbrain dopamine neuronal activity modulates splenic immunity
饮食中单糖和双糖含量的耐受曲线决定了小鼠的体重增加、肠道微生物群组成和认知能力。	Bartochowski, P.	PDF	N/A	Hormetic curve of dietary mono- and disaccharide content determines weight gain, gut microbiota composition and cognitive ability in mice
使用功能性超声进行移动人脑成像	Soloukey, S.	PDF	N/A	Mobile Human Brain Imaging using Functional Ultrasound
甘氨酸与GABAA受体之间对gephyrin的竞争控制了它们在抑制性突触处的平衡群体	Kostrz, D.	PDF	N/A	Competition between glycine and GABAA receptors for gephyrin controls their equilibrium populations at inhibitory synapses
大麻素对机械敏感K+通道的抑制作用	Docter, T.	PDF	N/A	Cannabinoid inhibition of mechanosensitive K+ channels
一种新颖的薄荷醇-DCMU漂白方法用于有孔虫：为共生研究生成无共生体的宿主	Schmidt, C.	PDF	N/A	A novel menthol-DCMU bleaching method for foraminifera: Generating aposymbiotic hosts for symbiosis research
SARS-CoV-2 Nsp4与宿主细胞ESCRT蛋白的协调作用诱导了内质网形态的变化。	Kifer, A.	PDF	N/A	Orchestration of SARS-CoV-2 Nsp4 and host-cell ESCRT proteins induces morphological changes of the endoplasmic reticulum
ATG16L1的WD结构域调控脂质运输，以维持细胞膜的完整性，从而限制流感病毒感染。	Bone, B.	PDF	N/A	ATG16L1 WD domain regulates lipid trafficking to maintain plasma membrane integrity to limit influenza virus infection
JAK2-STAT3通路的调控促进了人类诱导多能干细胞衍生的肌源性祖细胞的扩增和成熟	Caputo, L.	PDF	N/A	Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSCs-derived myogenic progenitor cells
回顾一下：在巴塔哥尼亚火山灰降落后，胡蜂属（Vespula spp.）的重新入侵情况。	Pereira, A. J.	PDF	N/A	Circling back: Vespula spp. re-invasion after knockout from volcanic ash fall in Patagonia
钴在河流生物膜中诱导新结构网络的形成：自养-异养耦合的损害。	Gourgues, S.	PDF	N/A	Cobalt induces the set-up of new structural network in river biofilms: Impairment of autotrophic-heterotrophic coupling.
好的火源：量化美国西部野火的有益生态作用（2010-2020年）	Balch, J. K.	PDF	N/A	Good fire: quantifying the beneficial ecosystem work of western U.S. wildfires (2010-2020)
全寄生植物Hydnoraceae中不同的重复序列揭示了基因组进化的游乐场	Kim, W.	PDF	N/A	Diverging repeatomes in holoparasitic Hydnoraceae uncover a playground of genome evolution
通用单拷贝敲入系统在秀丽隐杆线虫中的应用：一种质粒即可靶向所有染色体	Dinneen, E.	PDF	N/A	Universal Single Copy Knock-In System in Caenorhabditis elegans: One Plasmid to Target All Chromosomes
欧洲河七鳃鳗（Lampetra fluviatilis）和溪七鳃鳗（Lampetra planeri）全基因组组装的比较	Torresen, O. K.	PDF	N/A	Comparison of whole-genome assemblies of European river lamprey (Lampetra fluviatilis) and brook lamprey (Lampetra planeri)
PhenoEncoder：一种基因组数据压缩的判别嵌入方法	Tas, G.	PDF	N/A	PhenoEncoder: A Discriminative Embedding Approach to Genomic Data Compression
行为生物力学：切叶蚁的切割行为取决于叶片边缘的几何形状	Puffel, F.	PDF	N/A	Behavioural biomechanics: leaf-cutter ant cutting behaviour depends on leaf edge geometry
利用计算工具来理解雷公藤甲素与XPB的相互作用	Gorrie, D.	PDF	N/A	Leveraging computational tools to understand the triptolide-XPB interaction
膜焦磷酸酶运输H+的快速动力学：直接耦合机制的证据	Anashkin, V. A.	PDF	N/A	Rapid kinetics of H+ transport by membrane pyrophosphatase: evidence for a direct-coupling mechanism
一种可拉伸且仿生的聚氨酯膜，用于体外肺泡模型构建	Mitta, E.	PDF	N/A	A stretchable and biomimetic polyurethane membrane for lung alveolar in vitro modelling
NucleoSeeker - 精确过滤RNA数据库以整理高质量数据集	Upadhyay, U.	PDF	N/A	NucleoSeeker - Precision filtering of RNA databases to curate high-quality datasets
HIPSTR：TreeAnnotator X 中的最高独立后验子树重建	Baele, G.	PDF	N/A	HIPSTR: highest independent posterior subtree reconstruction in TreeAnnotator X
侵袭性乳腺癌的自组织是由主动和被动向错动力学的相互作用驱动的。	Gottheil, P.	PDF	N/A	Self organisation of invasive breast cancer driven by the interplay of active and passive nematic dynamics
肿瘤断裂负荷量化了与结构变异相关的基因组不稳定性，这种不稳定性在多种癌症中具有生物学和临床相关性。	Lakbir, S.	PDF	N/A	Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers
基质金属蛋白酶-2作为脂肪细胞葡萄糖利用的新型调节因子	Lempicki, M. D.	PDF	N/A	Matrix Metalloproteinase-2 as a novel regulator of glucose utilization by adipocytes
CLE4肽激素调控马铃薯的从头再生芽。	Gancheva, M.	PDF	N/A	CLE4 peptide hormone regulates de novo shoot regeneration in potato
识别发芽抑制剂CIPC的基因靶点	Grand, T. M.	PDF	N/A	Identification of Gene Targets for the Sprouting Inhibitor CIPC
离开科学：38个经合组织国家中生物学家的流失	Kwiek, M.	PDF	N/A	Leaving Science: Attrition of Biologists in 38 OECD Countries
性别差异对疼痛强度感知在疼痛方案标准化中的影响	Wragan, M.	PDF	N/A	The impact of sex differences on perceived pain intensity in pain protocol standardization
多组学整合与人类背根神经节蛋白质组学揭示TNFα信号传导为相关的性别二态性通路	Barry, A. M.	PDF	N/A	Multi-omic integration with human DRG proteomics highlights TNFα signalling as a relevant sexually dimorphic pathway
光照线索对颜色恒常性的影响在同时识别光照和反射率变化中的作用	Virtanen, L. S.	PDF	N/A	The effect of illumination cues on color constancy in simultaneous identification of illumination and reflectance changes
通过使用协变量分析和单倍型块对主要组织相容性复合体关联进行深入分析，揭示了艾滋病精英控制分子病因学的新机制。	Rahmouni, M.	PDF	N/A	Deep analysis of the Major Histocompatibility Complex associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS
评估氨基酸相似性感知k-mer在表示TCR库以进行分类时的实用性	Kockelbergh, H.	PDF	N/A	Evaluating the utility of amino acid similarity-aware kmers to represent TCR repertoires for classification
城市蜥蜴中极高的铅耐受性	Blanchette, A.	PDF	N/A	Extreme lead tolerance in an urban lizard
生命史策略能在多大程度上为物种保护规划提供信息？	Stevenson, E. A.	PDF	N/A	To what extent can life history strategies inform species conservation planning?
UniFORM：面向多重组织成像的通用免疫荧光标准化	Wang, K.	PDF	N/A	UniFORM: Towards Universal Immunofluorescence Normalization for Multiplex Tissue Imaging
影响组蛋白乙酰化的化学扰动调控结直肠癌的分化	Likasitwatanakul, P.	PDF	N/A	Chemical perturbations impacting histone acetylation governcolorectal cancer differentiation
大麻（Cannabis sativa L.）中新型白粉病抗性位点（PM2）的定位与特性研究	Seifi, S.	PDF	N/A	Mapping and characterization of a novel powdery mildew resistance locus (PM2) in Cannabis sativa L.
生长素和色氨酸在链藻（Penium margaritaceum）中引发了共同的反应。	Weijers, D.	PDF	N/A	Auxin and tryptophan trigger common responses in the streptophyte alga Penium margaritaceum
几丁质土壤改良通过增强模式触发的免疫来引发系统性植物抗病性。	Makechemu, M.	PDF	N/A	Chitin soil amendment triggers systemic plant disease resistance through enhanced pattern-triggered immunity
未加载和加载货物的液泡分选受体1的腔内结构域（VSR1-Nt）的两种晶体结构揭示了两个货物结合位点及其运输机制。	Borges, R. J.	PDF	N/A	The two crystal structures of unloaded and cargo-loaded Vacuolar Sorting Receptor 1 lumenal domain (VSR1-Nt) reveal two cargo binding sites and a mechanism of transport.
纳米比亚的仙女圈：土壤线虫的敌对领地	Treonis, A.	PDF	N/A	Namibian fairy circles: Hostile territory for soil nematodes
捕食者与猎物互动中的诚实信号：检验资源分配假说	Burdfield-Steel, E.	PDF	N/A	Honest signalling in predator-prey interactions: testing the resource allocation hypothesis
阿尔瓦雷斯龙类恐龙肉食性饮食的令人信服的证据	WANG, S.	PDF	N/A	Convincing Evidence of Carnivorous Diet in Alvarezsaurian Dinosaur
呼吸、咀嚼和吞咽过程中舌根形态变化的动态	Liu, Z.-J.	PDF	N/A	The Dynamics of Shape Changes in the Tongue Base during Respiration, Chewing and Swallowing
功能失调的振荡爆发模式是导致患有注意力缺陷多动障碍（ADHD）的青少年工作记忆缺陷的基础。	Kavanaugh, B.	PDF	N/A	Dysfunctional oscillatory bursting patterns underlie working memory deficits in adolescents with ADHD
小鼠同源皮层中多感官汇聚的空间组织	Patel, K. P.	PDF	N/A	Spatial organization of multisensory convergence in mouse isocortex
性别特异性单转录本水平的小鼠脑内加压素及其受体（AVPR1a）图谱	Gumerova, A. A.	PDF	N/A	Gender-specific Single Transcript Level Atlas of Vasopressin and its Receptor (AVPR1a) in the Mouse Brain
在不同亚型、区域和物种中寻找神经元放电率适应性的转录组相关性：一项Patch-seq分析	Meng, J. H.	PDF	N/A	In Search of Transcriptomic Correlates of Neuronal Firing-Rate Adaptation across Subtypes, Regions and Species: A Patch-seq Analysis
来自腹侧被盖区的GABA能神经元代表并调节力矢量。	Jiang, Q.	PDF	N/A	GABAergic neurons from the ventral tegmental area represent and regulate force vectors
干细胞因子对浦肯野细胞抑制的调控	Zaman, T.	PDF	N/A	Modulation of Purkinje Cell Inhibition by Stem Cell Factor
网格细胞预测动物未来的移动。	Csordas, D. E.	PDF	N/A	Grid cells anticipate the animal's future movement
跨多发性神经病的多组学人类腓肠神经特征分析	Heming, M.	PDF	N/A	Multi-omic characterization of human sural nerves acrosspolyneuropathies
针对脂质代谢的一类新型天然驱虫药物	Zahreddine, H.	PDF	N/A	A new class of natural anthelmintics targeting lipid metabolism
高分辨率转录组影响分析：AIRE致病性变异p.Arg257Ter、p.Cys311Tyr及多基因风险变异p.Arg471Cys的影响	Berger, A. H.	PDF	N/A	High-Resolution Transcriptional Impact of AIRE: Effects of Pathogenic Variants p.Arg257Ter, p.Cys311Tyr, and Polygenic Risk Variant p.Arg471Cys
当前的转录组数据库和通过免疫检查点阻断进行免疫治疗的生物标志物发现	Zhang, H.	PDF	N/A	Current transcriptome database and biomarker discovery for immunotherapy by immune checkpoint blockade
通过比较分析Bos基因组揭示印度牛的免疫遗传基础	Thambiraja, M.	PDF	N/A	Genetic basis of immunity in Indian cattle as revealed by comparative analysis of Bos genome
构建包容性领导力：生物科学视角	Armstrong, E. M.	PDF	N/A	Building Inclusive Leadership: A Biosciences Approach
多变量恢复力指标预测虫媒疾病暴发：西尼罗河病毒案例研究	Delecroix, C.	PDF	N/A	Multivariate resilience indicators to anticipate vector-borne disease outbreaks: a West Nile virus case-study
早期胚胎发育中的成像翻译	Bensidoun, P.	PDF	N/A	Imaging Translation in Early Embryo Development
全球干旱地区功能多样性的偏颇图景	Tordoni, E.	PDF	N/A	A skewed picture of functional diversity in global drylands
老化与脑血流动态的光谱特性	Park, K. Y.	PDF	N/A	Aging and the Spectral Properties of Brain Hemodynamics
加巴喷丁对人类背根神经节的影响：供体特异性电生理和转录组学特征	Demeter, J. B.	PDF	N/A	Gabapentin's Effect on Human Dorsal Root Ganglia: Donor-Specific Electrophysiological and Transcriptomic Profiles
部分人类脉络丛上皮细胞表现出线粒体偏心分布以及与色素生成相关的酶TYRP1的独特表达。	Groh, A. M.	PDF	N/A	A subset of human choroid plexus epithelial cells exhibit mitochondrial eccentricity and distinct expression of the pigmentation-associated enzyme TYRP1
FastReseg：利用转录本位置信息优化基于图像的细胞分割结果，应用于空间转录组学	Wu, L.	PDF	N/A	FastReseg: using transcript locations to refine image-based cell segmentation results in spatial transcriptomics
UltimateSynth：适用于多对比度AI的磁共振成像物理学	Adams, R.	PDF	N/A	UltimateSynth: MRI Physics for Pan-Contrast AI
揭示核蛋白质的远程异质性组织与N6-甲基腺苷足迹法	Yang, W.	PDF	N/A	Revealing long-range heterogeneous organization of nucleoproteins with N6-methyladenine footprinting
细胞铁代谢失调会使对化疗产生抗性的癌细胞更容易发生铁死亡。	Loftus, L.	PDF	N/A	Dysregulation of cellular iron predisposes chemotherapy resistant cancer cells to ferroptosis
去神经支配的交感神经-β3肾上腺素受体介导的脂肪组织脂解作用减弱可减轻小鼠酒精性肝损伤	Wickramasinghe, P.	PDF	N/A	Ablation of sympathetic nerve-β3 adrenergic receptor-mediated adipose tissue lipolysis attenuates alcohol-induced liver injury in mice
九重atg8突变体为拟南芥中ATG8同工型的功能特化提供了遗传学证据	Del Chiaro, A.	PDF	N/A	Nonuple atg8 mutant provides genetic evidence for functional specialization of ATG8 isoforms in Arabidopsis thaliana
Pol II的降解会独立于转录丧失而激活细胞死亡。	Harper, N. W.	PDF	N/A	Pol II degradation activates cell death independently from the loss of transcription
FedPyDESeq2：一种用于批量RNA-seq差异表达分析的联邦框架	Muzellec, B.	PDF	N/A	FedPyDESeq2: a federated framework for bulk RNA-seq differential expression analysis
跨越平面空间转录组学到三维细胞图谱的维度鸿沟	Lin, S.	PDF	N/A	Bridging the Dimensional Gap from Planar Spatial Transcriptomics to 3D Cell Atlases
一种新型双特异性抗体CVL006在癌症治疗中对PD-L1和VEGF的双重靶向作用优于AK112	Wang, C.	PDF	N/A	A Novel Bispecific Antibody CVL006 Superior to AK112 for Dual Targeting of PD-L1 and VEGF in Cancer Therapy
大规模微血管网络中的血流模拟与不确定性量化：应用于脑皮层网络	Rasmussen, P. M.	PDF	N/A	Blood flow simulation and uncertainty quantification in extensive microvascular networks: Application to brain cortical networks
触觉刺激减少或促进听觉流的分离：心理物理学与建模	Darki, F.	PDF	N/A	Tactile stimulations reduce or promote the segregation of auditory streams: psychophysics and modelling
从新的果蝇疾病模型中洞察齿状核-红核-苍白球-路易体萎缩症	Prifti, M. V.	PDF	N/A	Insights into Dentatorubral-Pallidoluysian Atrophy from a new Drosophila model of disease
脑机接口神经解码算法的比较分析	Shevchenko, O.	PDF	N/A	Comparative analysis of neural decoding algorithms for brain-machine interfaces
在1型糖尿病早期，传统和调节性T细胞亚群中幼稚和效应T细胞表型的失衡	Niederlova, V.	PDF	N/A	An imbalance of naive and effector T-cell phenotypes in early type 1 diabetes across conventional and regulatory subsets
GM-CSF通过激活多种信号通路，在军团菌感染期间增强了人单核细胞中的促炎性细胞因子反应。	Vazquez Marrero, V. R.	PDF	N/A	GM-CSF engages multiple signaling pathways to enhance pro-inflammatory cytokine responses in human monocytes during Legionella infection
果蝇中的sev-GAL4驱动因子不在幼虫腹神经节的八对背内侧神经元及其他一些神经元中表达：一项修正	Kaushik, V.	PDF	N/A	The sev-GAL4 driver in Drosophila melanogaster does not express in the eight pairs of dorso-medial and some other neurons in larval ventral ganglia: A correction
在一种寿命较短的负鼠的生殖细胞中，突变率低但雄性偏向明显	Pena-Garcia, Y.	PDF	N/A	Low mutation rate but high male-bias in the germline of a short-lived opossum
二倍体起源、适应多倍化以及异源四倍体拟南芥瑞典种（Arabidopsis suecica）中重新二倍化的开始	Burns, R.	PDF	N/A	Diploid origins, adaptation to polyploidy, and the beginning of rediploidization in allotetraploid Arabidopsis suecica
一种用于癌症免疫治疗的新型通用嵌合抗原受体（CAR）-片段抗体结合剂（FAB）分裂系统	Arina, A.	PDF	N/A	A new universal chimeric-antigen receptor (CAR)- fragment antibody binder (FAB) split system for cancer immunotherapy
DRUGSYNC：使用基于GCN图卷积网络和预学习的药物诱导基因表达谱来预测协同药物组合	Zhao, L.	PDF	N/A	DRUGSYNC: Prediction of Synergistic Drug Combinations Using GCN Graph Convolutional Network based and Pre-learned Drug-induced Gene Expression Profiles
DiscoEPG：一个用于昆虫电穿透图（EPG）信号特征分析的Python包	Dinh, Q. D.	PDF	N/A	DiscoEPG: A Python package for characterization of insect electrical penetration graph (EPG) signals
改进多重蛋白质组学研究的实验设计和数据标准化	Fang, H.	PDF	N/A	Improving design and normalization of multiplex proteomics study
基于其近原子分辨率结构，进行一种荧光共振能量转移（FRET）实验，以定量测定人类β-心脏肌球蛋白相互作用头模体的水平。	Goluguri, R. R.	PDF	N/A	A FRET assay to quantitate levels of the human β-cardiac myosin interacting heads motif based on its near-atomic resolution structure
纳米颗粒在三维肿瘤模型中的积累与渗透：尺寸、形状和表面电荷的影响	Cybulski, P.	PDF	N/A	Nanoparticle Accumulation and Penetration in 3D Tumor Models: the Effect of Size, Shape, and Surface Charge
实验设计与系统松散性对个性化过程的影响：从心血管角度探讨	Saxton, H.	PDF	N/A	THE IMPACT OF EXPERIMENTAL DESIGNS & SYSTEM SLOPPINESS ON THE PERSONALISATION PROCESS: A CARDIOVASCULAR PERSPECTIVE
从基于生物学的初级视觉皮层学习脉冲神经网络模型中，稀疏编码、平衡和去相关性的出现	Ruslim, M. A.	PDF	N/A	Emergence of Sparse Coding, Balance and Decorrelation from a Biologically-Grounded Spiking Neural Network Model of Learning in the Primary Visual Cortex
SARITA：一种用于生成SARS-CoV-2刺突蛋白S1亚基的大型语言模型	Rancati, S.	PDF	N/A	SARITA: A Large Language Model for Generating the S1 Subunit of the SARS-CoV-2 Spike Protein
SARS-CoV-2包膜PDZ结合基序作为一种毒力因子，破坏宿主的上皮细胞间连接。	Alvarez, F.	PDF	N/A	The SARS-CoV-2 envelope PDZ Binding Motif acts as a virulence factor disrupting host's epithelial cell-cell junctions
在阿尔茨海默病小鼠模型中，SARS-CoV-2感染加速了淀粉样蛋白的沉积。	Parekh, P. A.	PDF	N/A	Accelerated amyloid deposition in SARS-CoV-2 infected mouse models of Alzheimer's disease
卡塔尔手工艺和体力劳动者接种基于BNT162b2 mRNA的COVID-19加强疫苗后的纵向细胞和体液免疫反应。	Thomas, R.	PDF	N/A	Longitudinal cellular and humoral immune responses following Covid-19 BNT162b2-mRNA-based booster vaccination of craft and manual workers in Qatar.
COVID-19患者中分枝杆菌的差异性控制与CD28+ CD8+ T细胞相关	Llibre, A.	PDF	N/A	Differential control of mycobacteria among COVID-19 patients is associated with CD28+ CD8+ T cells
在大规模队列中的GWAS显著性阈值	Cheruiyot, E.	PDF	N/A	GWAS significance thresholds in large cohorts
投资开放科学：资助者的关键考虑因素	Cobb-Lewis, D. E.	PDF	N/A	Investing in Open Science: Key Considerations for Funders
在执行抓取任务时，主导手和非主导手在神经和行为表现上具有可比性。	Balasubramanian, E.	PDF	N/A	Comparable neural and behavioural performance in dominant and non-dominant hands during grasping tasks
对SARS-CoV-2 KP.3.1.1刺突蛋白进化的结构和功能洞察	Feng, Z.	PDF	N/A	Structural and Functional Insights into the Evolution of SARS-CoV-2 KP.3.1.1 Spike Protein
一个预测机车地面反作用力的简单分析模型	Opolz, M. D.	PDF	N/A	A simple analytical model for predicting locomotive ground reaction forces
线粒体与核DNA在基因表达调控中的相互作用	Giannoulis, X.	PDF	N/A	Interplay between mitochondrial and nuclear DNA in gene expression regulation
资源环境的变化驱动了黑腹果蝇（Drosophila melanogaster）的适应性分化。	Beltz, J. K.	PDF	N/A	Variation in Resource Environment Drives Adaptive Divergence in Drosophila melanogaster
谱系相关的人类分化配对基因（DPGs）表现出调控特征和进化趋势	Duan, G.	PDF	N/A	Lineage-associated Human Divergently-Paired Genes (DPGs) Exhibit Regulatory Characteristics and Evolutionary Trends
一种新型HLA II类抗原呈递预测算法揭示了KRAS G12C特异性的免疫原性CD4表位	Sprague, D.	PDF	N/A	A novel HLA Class II presentation prediction algorithm deciphers immunogenic CD4 epitopes specific to KRAS G12C
可逆且可重复使用的分隔式微流控芯片，用于背根神经节神经元的共培养	Moreau, S.	PDF	N/A	Reversible and reusable compartmentalized microfluidic chip for coculture of dorsal root ganglion neurons
SOX2诱导的IL-1α介导的免疫抑制推动了上皮异型增生向恶性转化的进程。	Taner, H. F.	PDF	N/A	SOX2-induced IL-1alpha-mediated immune suppression drives epithelial dysplasia malignant transformation
分类群：利用几何形态测量学和机器学习区分袋鼠后颅骨以应用于动物考古学	Mein, E.	PDF	N/A	Sorting the mob: using geometric morphometrics and machine learning to differentiate kangaroo postcrania for zooarchaeological applications
在小鼠中通过转基因增强红血球生成素（erythroferrone）的表达，可以改善腺嘌呤诱导的慢性肾病中的贫血症状。	Czaya, B.	PDF	N/A	Transgenic augmentation of erythroferrone in mice ameliorates anemia in adenine-induced chronic kidney disease
元素分区、元素定位及海枣树暴露于NaCl后的转录组响应	Pongrac, P.	PDF	N/A	Element partitioning, element localisation and transcriptome responses of date palms exposed to NaCl
人类脉络丛微血管灌注和液体隔室的选择性放松扩散加权成像	Li, C.	PDF	N/A	Relaxation selective Intravoxel Incoherent Motion Imaging of Microvascular Perfusion and Fluid Compartments in the Human Choroid Plexus
Collablots：量化胶原蛋白VI水平及其在胶原蛋白VI相关性肌营养不良症患者细胞培养中的结构紊乱情况	Osegui-Barcenilla, N.	PDF	N/A	Collablots: Quantification of collagen VI levels and its structural disorganisation in cell cultures from patients with collagen VI-related dystrophies
供体HLA DQ反应性B细胞在慢性免疫抑制下克隆性扩增，并包括具有高亲和力胚系B细胞受体的非典型CD21低CD27- B细胞。	Russum, S.	PDF	N/A	Donor HLA DQ reactive B cells clonally expand under chronic immunosuppression and include atypical CD21lowCD27- B cells with high avidity germline B cell receptors.
2009年至2020年间从人类流感A病毒株中分离出的N1神经氨酸酶的抗原图谱	Portela Catani, J. P.	PDF	N/A	The antigenic landscape of N1 neuraminidase in human influenza A virus strains isolated between 2009 and 2020
对多细胞排列的整体分析将胚胎组织的多样性简化为两种原型，这两种原型需要特定的钙粘蛋白表达。	Brambach, M.	PDF	N/A	In toto analysis of multicellular arrangement reduces embryonic tissue diversity to two archetypes that require specific cadherin expression
热带森林土壤微生物群在升温条件下比在常温条件下对叶片耐热性的调节作用更强。	Hernandes Villani, G.	PDF	N/A	Tropical Forest Soil Microbiome Modulates Leaf Heat Tolerance More Strongly Under Warming than Ambient Conditions
通过深度代理模型实现可扩展的DNA特征生成与转录因子结合预测	Kabir, A.	PDF	N/A	Scalable DNA Feature Generation and Transcription Factor Binding Prediction via Deep Surrogate Models
Scouter：利用大型语言模型嵌入预测基因扰动后的转录反应	Zhu, O.	PDF	N/A	Scouter: Predicting Transcriptional Responses to Genetic Perturbations with LLM embeddings
针对A类G蛋白偶联受体的安全药物大规模筛选的微调深度迁移学习模型	Provasi, D.	PDF	N/A	Fine-Tuned Deep Transfer Learning Models for Large Screenings of Safer Drugs Targeting Class A G Protein-Coupled Receptors
演示磁带：靶向单细胞测序数据的计算解复用	Borgsmueller, N.	PDF	N/A	DemoTape: Computational demultiplexing of targeted single-cell sequencing data
使用MPI并行化基于粒子的反应扩散模拟	Guo, S.	PDF	N/A	Parallelization of particle-based reaction-diffusion simulations using MPI
# BioRxiv 2024-12-09 Papers

标题	作者	PDF链接	代码仓库	Title
混合交配系统中的中性遗传多样性	Uyenoyama, M. K.	PDF	N/A	Neutral genetic diversity in mixed mating systems
早期生活压力引发与恐惧泛化相关的持续性星形胶质细胞功能障碍。	Guayasamin, M.	PDF	N/A	Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation
撤回：增强突变热点预测：原子波动的作用	Martis, E. A. F.	PDF	N/A	WITHDRAWN: Enhancing Mutational Hotspot Predictions: The Role of Atomic Fluctuations
使用在横截面数据上预训练的规范模型来评估神经影像数据中的个体内部纵向变化	Rehak Buckova, B.	PDF	N/A	Using normative models pre-trained on cross-sectional data to evaluate intra-individual longitudinal changes in neuroimaging data
细胞膜通过胆固醇不对称性维持磷脂不平衡	Doktorova, M.	PDF	N/A	Cell Membranes Sustain Phospholipid Imbalance Via Cholesterol Asymmetry
QInfoMating：性选择与选型交配估计软件	Carvajal-Rodriguez, A.	PDF	N/A	QInfoMating: Sexual Selection and Assortative Mating Estimation Software
HERV的激活将ME/CFS与纤维肌痛区分开来，同时定义了一个新的疾病分类实体。	Gimenez-Orenga, K.	PDF	N/A	HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity
基于文库的单细胞RNA测序中辅助性T细胞亚群的映射与时间追踪	Lukyanov, D. K.	PDF	N/A	Repertoire-based mapping and time-tracking of helper T cell subsets in scRNA-Seq
睾酮诱导的精囊上皮细胞代谢变化会改变血浆成分，从而增强精子生育能力。	Yamanaka, T.	PDF	N/A	Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility
来自辐射杂交和CRISPRi的互补人类基因相互作用图谱	Smith, D. J.	PDF	N/A	Complementary human gene interaction maps from radiation hybrids and CRISPRi
肾小球弹性与基因表达模式定义了Alport肾病的两个阶段	Yoon, J.	PDF	N/A	Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
MdfA是一种新型的ClpC适配蛋白，在枯草芽孢杆菌孢子的发育过程中发挥作用。	Massoni, S. C.	PDF	N/A	MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore
特定PIP2亚型组成的识别触发了别构控制机制，该机制用于选择性膜定位内质网固醇转运蛋白StarD4的货物装载和释放功能。	Xie, H.	PDF	N/A	Recognition of specific PIP2-subtype composition triggers the allosteric control mechanism for selective membrane targeting of cargo loading and release functions of the intracellular sterol transporter StarD4
在羊膜动物原肠胚形成过程中，左右组织者形成之前，双侧细胞流动呈现出不对称性。	Asai, R.	PDF	N/A	Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation
视觉的第一个突触处存在一种异质性群体编码	Herzog, T.	PDF	N/A	A heterogeneous population code at the first synapse of vision
通过生成式深度学习对高度动态蛋白质的构象集合进行采样	Ruzmetov, T.	PDF	N/A	Sampling Conformational Ensembles of Highly Dynamic Proteins via Generative Deep Learning
将翻译后的数字数据编码到哺乳动物细胞群体的基因组中	Callisto, A.	PDF	N/A	Post-translational digital data encoding into the genomes of mammalian cell populations
从解剖学角度来看，大脑皮层通过慢速（1-8Hz）和快速（70-120Hz）振荡活动对音乐和语言进行不同的追踪。	Osorio, S.	PDF	N/A	Anatomically distinct cortical tracking of music and speech by slow (1-8Hz) and fast (70-120Hz) oscillatory activity
在小麦根际中，假单胞菌的分类和功能微多样性是因品种而异的，并且与抗病性特征和根直径有关。	Herms, C. H.	PDF	N/A	Pseudomonas taxonomic and functional microdiversity in the wheat rhizosphere is cultivar-dependent and links to disease resistance profile and root diameter
Oviductin决定了哺乳动物透明带（zona pellucida）的种属特异性。	de la Fuente, D.	PDF	N/A	Oviductin sets the species-specificity of the mammalian zona pellucida
一个动力学简单行走模型修正了恢复率的定义：人类行走在大支撑阶段与摆动运动有显著偏离	Hosseini-Yazdi, S.-S.	PDF	N/A	A Powered Simple Walking Model Modifies the Rate of Recovery Definition: Human Walking Deviates Drastically from Pendular Motion During the Double Support Phase
通过非自主元件的调控来维持长期的可转座元件活性	Omole, A. D.	PDF	N/A	Maintenance of long-term transposable element activity through regulation by nonautonomous elements
天蝎座：增强嵌入以改善DNA序列的下游分析	Refahi, M.	PDF	N/A	Scorpio : Enhancing Embeddings to Improve Downstream Analysis of DNA sequences
质心工作分析估计不同行走条件下的首选步行速度	Hosseini-Yazdi, S.-S.	PDF	N/A	Center of Mass Work Analysis Estimates Preferred Walking Speeds for Varying Walking Conditions
解耦冠状病毒Nsp1的功能角色	Baeumlin, E.	PDF	N/A	Uncoupling the functional roles of Coronavirus Nsp1
定期更新的基准数据集，用于对AlphaFold应用进行统计正确的评估	Dobson, L.	PDF	N/A	Regularly updated benchmark sets for statistically correct evaluations of AlphaFold applications
重新审视脑脊液的等效光学特性以提高基于扩散的大脑建模精度	Lewis, A.	PDF	N/A	Revisiting equivalent optical properties for cerebrospinal fluid to improve diffusion-based modeling accuracy in the brain
碳酸酐酶抑制剂可预防脑淀粉样变性模型中无症状的毛细血管血流紊乱。	Gutierrez-Jimenez, E.	PDF	N/A	Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis
功能失调的机械传导调节了PIK3CA驱动的血管畸形的进展	Aw, W. Y.	PDF	N/A	Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations
使用深度学习在冷冻电镜和X射线图中识别配体	Karolczak, J.	PDF	N/A	Ligand Identification in CryoEM and X-ray Maps Using Deep Learning
响应多样性是复杂食物网中时间稳定性的主要驱动力。	Danet, A.	PDF	N/A	Response diversity is a major driver of temporal stability in complex food webs
高数据率大分子晶体学（HDRMX）的大规模压缩：对衍射数据及后续结构分析的影响	Bernstein, H. J.	PDF	N/A	Massive Compression for High Data Rate Macromolecular Crystallography (HDRMX): Impact on Diffraction Data and Subsequent Structural Analysis
物体非刚性各向异性：皮层各向异性对高级知觉的影响	Maruya, A.	PDF	N/A	Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy
运动学习利用协调的低频皮层-基底神经节活动来优化帕金森病患者运动准备	Presbrey, K. N.	PDF	N/A	Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson's Disease
利用蚂蚁共生体制作酸奶揭示了用于食品发酵的细菌、酸和酶。	Sinotte, V. M.	PDF	N/A	Making yogurt with the ant holobiont uncovers bacteria, acids, and enzymes for food fermentation
使用静息态fMRI的因果关系映射揭示了精神分裂症患者的高活动性和低连接性	Tahir, A.	PDF	N/A	Causality Mapping Using Resting-state fMRI Reveals Hyperactivity and Hypoconnectivity in Schizophrenia Patients
抑制性可塑性调控中时间精度与效应幅度之间的权衡决定了学习表征的可分离性。	Rubisch, P.	PDF	N/A	The trade-off between temporal precision and effect amplitude of inhibitory plasticity regulation determines separability of learned representations
在营养生长期暴露于高pH胁迫下的豌豆中的转录重编程与微生物群动态	Thapa, A.	PDF	N/A	Transcriptional reprogramming and microbiome dynamics in garden pea exposed to high pH stress during vegetative stage
在感染猿猴免疫缺陷病毒（SIV）的恒河猴中，大麻素能够改变基底神经节的miRNA m6A甲基化谱，使其趋向于抗炎表型。	Okeoma, C. M.	PDF	N/A	Cannabinoids shift the basal ganglia miRNA m6A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques
鉴定和靶向气道上皮细胞中SARS-CoV-2-宿主相互作用的调节因子。	Dirvin, B. G.	PDF	N/A	Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium.
在嗜盐碱杆菌（Haloferax volcanii）的生长周期中，古菌微管蛋白样蛋白CetZ1和CetZ2对细胞形态具有相反的影响。	Brown, H. J.	PDF	N/A	Archaeal tubulin-like proteins CetZ1 and CetZ2 have opposing effects on cell morphology during the growth cycle of Haloferax volcanii
全小鼠肾小球纳米级光学成像、重建与空间分析	Ali, A.	PDF	N/A	Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse Glomeruli
Kauffman模型中闭合与开放式进化之间因果关系的证据	Faggian, M. F.	PDF	N/A	Evidence of causality between Closure and Open-Ended Evolution in the Kauffman model
皮质层次结构中神经编码的变化：从稀有的类别性到始终的高维度	Posani, L.	PDF	N/A	Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy
卵巢生殖干细胞的去分化是依赖于细胞突的。	Sutcliffe, C.	PDF	N/A	Ovarian germline stem cell dedifferentiation is cytoneme-dependent
侧孢曲霉：一种在日本新出现的隐匿性曲霉病病原体	Shibata, S.	PDF	N/A	Aspergillus latus: a cryptic causative agent of aspergillosis emerging in Japan
在高维数据空间中，是使用更多的潜在变量还是更少的潜在变量？这就是问题所在。	Vaccari, F. E.	PDF	N/A	More or fewer latent variables in the high-dimensional data space? That is the question
CAFE：一种集成式网络应用程序，用于光谱流式细胞术中的高维数据分析与可视化	Siam, M. H. B.	PDF	N/A	CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry
自发脑活动背后的神经受体和转运蛋白	Nakuci, J.	PDF	N/A	The neuroreceptors and transporters underlying spontaneous brain activity
一种心血管-肾脏-代谢综合征的小鼠模型显示，在缺血的后肢中，肢体功能受损。	Chitalia, V.	PDF	N/A	A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limb
元预测扩展了人类大脑皮层和皮层下区域的奖励学习机制。	Shin, J.	PDF	N/A	Meta-prediction extends human cortical and subcortical reward learning
重复节奏模式有助于音乐节拍的神经表征	Coulon, E.	PDF	N/A	Repetition of Rhythmic Patterns Fosters Neural Representation of Musical Meter
将人类基因组演化的历程进行划分	Pagani, L.	PDF	N/A	Partitioning the genomic journey to becoming Homo sapiens
CCNB1IP1顺式调控的进化推动了灵长类动物皮层大小和折叠程度的逐渐增加	Hu, T.	PDF	N/A	Cis-Regulatory Evolution of CCNB1IP1 Driving Gradual Increase of Cortical Size and Folding in primates
超越二分法：大鼠超声波发声的多样性	Wada, R.	PDF	N/A	Beyond dichotomy: diversity of rat's ultrasonic vocalizations
人类对声音而非触觉节奏的行为相关分段神经表征	Lenoir, C.	PDF	N/A	Behavior-relevant periodized neural representation of acoustic but not tactile rhythm in humans
与帕金森病相关的Pink1缺失会破坏包裹性胶质细胞中的囊泡运输，导致多巴胺能神经元突触丧失。	Ghezzi, L.	PDF	N/A	Parkinson's disease-associated Pink1 loss disrupts vesicle trafficking in ensheathing glia causing dopaminergic neuron synapse loss
基于PDMS的微流控芯片组件的时间分辨冷冻电镜（TRCEM）样品制备	Feng, X.	PDF	N/A	Time-resolved cryo-EM (TRCEM) sample preparation using a PDMS-based microfluidic chip assembly
通过冷冻电镜揭示的自然华丽的仅由RNA组成的复合物	Kretsch, R. C.	PDF	N/A	Naturally ornate RNA-only complexes revealed by cryo-EM
利用淋巴结探寻者64Cu标记的革兰氏阴性菌外泌体进行脑脊液淋巴引流PET成像	Kim, K.	PDF	N/A	Lymphatic drainage of cerebrospinal fluid using lymph node seeker 64Cu-labeled Gram-negative bacterial extracellular vesicles PET
mTOR信号通路通过S6K1-RhoA和aPKC-Lgl2轴调控上皮细胞顶端突起的形成。	Sen, S.	PDF	N/A	mTOR signaling governs the formation of epithelial apical projection via S6K1-RhoA and aPKC-Lgl2 axes
生成用于研究精子中线粒体的转基因小鼠模型	Sarkar, H.	PDF	N/A	Generation of a Transgenic Mouse Model for Investigating Mitochondria in Sperm
通过联合过表达筛选，我们发现PIPPI是一种与内质网应激反应相关的新型微蛋白。	Lafranchi, L.	PDF	N/A	Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response
细胞体积调控培养的人表皮角质形成细胞的终末分化	Watt, F. M.	PDF	N/A	Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes
人类白细胞中细胞类型特异性的自噬	Dang, L.	PDF	N/A	Cell-type specific autophagy in human leukocytes
微纤维模板孔凝胶生物墨水实现管状界面及微血管化，直至3D生物打印的基本构建单元	Guo, Y.	PDF	N/A	Microfiber-Templated Porogel Bioinks Enable Tubular Interfaces and Microvascularization Down to the Building Blocks for 3D Bioprinting
脂质的恒定pH分子动力学模拟	Trollmann, M. F. W.	PDF	N/A	Constant-pH MD Simulations of Lipids
人CFTR开放状态的结构和氯离子传导特性	Zeng, Z. W.	PDF	N/A	Structure and Cl-Conductance Properties of the Open State of Human CFTR
TRIM5α PRYSPRY结构域与HIV衣壳无序相互作用界面的全原子视角	Haas-Neill, L.	PDF	N/A	An all-atom view into the disordered interaction interface of the TRIM5α PRYSPRY domain and the HIV capsid
神经回路机制在支配特质与社会竞争中的作用	Yan, H.	PDF	N/A	Neural Circuit Mechanisms Underlying Dominance Traits and Social Competition
T细胞白血病中LMO2的降解会导致转录复合物伙伴的连带破坏以及LMO2依赖的细胞凋亡。	Sereesongsaeng, N.	PDF	N/A	Degradation of LMO2 in T cell leukaemia causes collateral breakdown of transcription complex partners and LMO2-dependent apoptosis
使用生物发光共振能量转移技术检测7TM受体的基础性和配体依赖性Gi导向活性的关键策略	Endzhievskaya, S.	PDF	N/A	Essential strategies for the detection of constitutive and ligand-dependent Gi-directed activity of 7TM receptors using bioluminescence resonance energy transfer
血管抑制素是由肾素-血管紧张素系统产生的。	Nunez, F. F.	PDF	N/A	Vasoinhibin is Generated by the Renin-Angiotensin System
微血管保护和心肌细胞增生是先天性心脏病相关肺动脉高压中右心室适应性发育的基础。	Smith, M. A.	PDF	N/A	Microvascular preservation and cardiomyocyte hyperplasia underlie adaptive right ventricular development in congenital heart disease-associated pulmonary arterial hypertension
基于先天适应性的早期运动训练的共享与独特适应性	Sadler, D. G.	PDF	N/A	Shared and distinct adaptations to early-life exercise training based on inborn fitness
转录组与代谢的综合分析揭示了氧化还原稳态在羊草低光和盐复合胁迫中的功能作用	Qu, M.	PDF	N/A	Integrative analysis of transcriptome and metabolism reveals functional roles of redox homeostasis in low light and salt combined stress in Leymus chinensis
利用INSIGHT技术在体内揭示扩散性胶质母细胞瘤细胞的信号网络	Ahn, R.	PDF	N/A	Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT
FTO（脂肪量和肥胖相关蛋白）缺乏会加重与年龄相关的抑郁样行为和认知功能障碍。	Li, M.	PDF	N/A	FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment
自上而下的注意力和阿尔茨海默病的病理影响在学习过程中对皮层的选择性，影响老年人的情景记忆。	Sheng, J.	PDF	N/A	Top-down attention and Alzheimer's pathology impact cortical selectivity during learning,influencing episodic memory in older adults
活体中感觉轴突的口径在空间和时间上都有变化，并受细胞微环境的影响。	Ching, K.	PDF	N/A	Caliber of sensory axons in vivo varies spatially and temporally and is influenced by the cellular microenvironment
抑制性连接的空间约束对尖峰网络中临界性动态发展的影响	Kern, F. B.	PDF	N/A	Effects of Spatial Constraints of Inhibitory Connectivity on the Dynamical Development of Criticality in Spiking Networks
年龄相关的糖萼重塑驱动T细胞耗竭	Zhang, H.	PDF	N/A	Age-related remodeling of the glycocalyx drives T cell exhaustion
一种人畜共患的H5N1血凝素结构揭示了一个被自身糖基占据的受体结合位点。	Morano, N. C.	PDF	N/A	Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan
利用冷冻电镜直接从免疫血清中发现功能性和表位特异性的单克隆抗体	Ferguson, J. A.	PDF	N/A	Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryoEM
转录组学图谱及伤口床周围的免疫微环境定义了小鼠指尖截肢后的再生与非再生结果	Prabahar, A.	PDF	N/A	Transcriptomic Landscape and Immune Microenvironment AroundWound Bed Define Regenerative versus Non-regenerative Outcomesin Mouse Digit Amputation
揭示真食虫动物中微生物的多样性、传播途径及其人畜共患潜力	Li, H.	PDF	N/A	Unveiling the diversity, transmission, and zoonotic potential of microbes in true insectivores
在混合小鼠多样性面板中，盐性和可卡因自我给药的遗传差异	Khan, A. H.	PDF	N/A	Differing genetics of saline and cocaine self administration in the hybrid mouse diversity panel
利用3D生物打印的人类皮肤等效物识别强力HSV抗病毒药物	Ellison, S. T.	PDF	N/A	Identification of potent HSV antivirals using 3D bioprinted human skin equivalents
载有神经递质的DNA纳米笼作为基于α-突触核蛋白的神经病变细胞和体内潜在治疗剂	Vaswani, P.	PDF	N/A	Neurotransmitter loaded DNA nanocages as potential therapeutics for α-synuclein based neuropathies in cells and in vivo
磁力诱导磁小体链（MAGiC）：一种高性能且可导航的生物磁性粒子成像示踪剂	Li, L.	PDF	N/A	Magnetically induced magnetosome chain (MAGiC):A biogenic magnetic-particle-imaging tracer with high performance and navigability
酵母知识图谱数据库，用于探索酿酒酵母和裂殖酵母	Kumar, M. R.	PDF	N/A	Yeast Knowledge Graphs Database for Exploring Saccharomyces cerevisiae and Schizosaccharomyces pombe
超越细胞聚类和特征聚合：单细胞ATAC-seq数据中是否存在单细胞水平的信息？	Kwok, A. W. C.	PDF	N/A	Going beyond cell clustering and feature aggregation: Is there single cell level information in single-cell ATAC-seq data?
MEGA-FISH：面向大规模空间组学的多组学可扩展GPU加速FISH处理框架	Ito, Y.	PDF	N/A	MEGA-FISH: Multi-omics Extensible GPU-Accelerated FISH Processing Framework for Huge-Scale Spatial Omics
四种皮肤类型中用于维生素D3合成的太阳紫外线B辐射 - 模型传播研究	Pasricha, P. K.	PDF	N/A	Solar UVB Radiation for the Synthesis of Vitamin D3 in Four Skin Types - Model Propagation Studies
新见解：槲皮素金属离子螯合物对红斑减少的作用	Bolano Alvarez, A.	PDF	N/A	New insight into erythema reduction induced by quercetin metal ions chelates
HIV-1 Rev蛋白形成一个锌连接的二聚体。	Khan, R. S.	PDF	N/A	HIV-1 Rev Protein Forms a Zinc-Linked Dimer
在单细胞水平上识别疾病特异性易损状态	D'Antuono, M.	PDF	N/A	Identification of disease-specific vulnerability states at the single-cell level
一个针对真核生物线粒体细胞色素氧化酶亚基I基因（eKOI）的新型分类数据库：在宏条形码分析中提高群落水平的分类分辨率	Gonzalez-Miguens, R.	PDF	N/A	A Novel Taxonomic Database for eukaryotic Mitochondrial Cytochrome Oxidase subunit I Gene (eKOI): Enhancing taxonomic resolution at community-level in metabarcoding analyses
从灾难到侵袭：通过森林结构和气象分析，将风灾树木损害与树皮甲虫爆发联系起来	Torresani, M.	PDF	N/A	From calamity to infestation: linking windstorm tree damage to bark beetle outbreak through forest structure and meteorological analysis
跨越物种界限：环境DNA和基因分析揭示了美洲鳗鱼分布末端的杂交定居	Jacobsen, M. W.	PDF	N/A	Bridging species boundaries: eDNA and genetic analysis reveal hybrid settlement at the very end of American eel distribution
成年人类下丘脑中单细胞分辨率的空间解析分子性别差异	Mulvey, B.	PDF	N/A	Spatially-resolved molecular sex differences at single cell resolution in the adult human hypothalamus
通过整合静电纺膜和流动在肾小球共培养中生物制造过滤屏障	mussoni, c.	PDF	N/A	Biofabrication of a filtration barrier by integrating electrospun membranes and flow in a glomerular co-culture
用于血友病A基因治疗的工程化凝血因子VIII，具有增强的分泌和凝血潜力	Kashiwakura, Y.	PDF	N/A	Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy
将人口聚类与基因组流行病学整合于PopPIPE	McHugh, M. P.	PDF	N/A	Integrated population clustering and genomic epidemiology with PopPIPE
NCPepFold：通过多粒度表示的环化优化实现非规范环肽结构的准确预测	Mao, Q.	PDF	N/A	NCPepFold: Accurate Prediction of Non-canonical Cyclic Peptide Structures via Cyclization Optimization with Multigranular Representation
CCR1抑制增强了多发性骨髓瘤细胞对糖皮质激素治疗的敏感性。	Luyckx, B.	PDF	N/A	CCR1 inhibition sensitizes multiple myeloma cells toglucocorticoid therapy
在癌症中追逐不存在的微小RNA	Orang, A.	PDF	N/A	Chasing non-existent microRNAs in cancer
骨保护素与纤维调节蛋白-1的相互作用对于纤维化肺组织中细胞外基质的沉积至关重要。	Liu, Y.	PDF	N/A	Interaction of osteoprotegerin with fibulin-1 is essential for extracellular matrix deposition in fibrotic lung tissue
ARID1A诱导的转录重编程重塑了黑色素瘤中对药物治疗的信号响应。	Barker, C. G.	PDF	N/A	ARID1A-induced transcriptional reprogramming rewires signalling responses to drug treatment in melanoma
自我信念形成的时间相关波动	Mayer, A. V.	PDF	N/A	Time-of-day related fluctuations of self-belief formation
动词-小品词结构的认知动态：一项眼动研究	Kissane, H.	PDF	N/A	Cognitive Dynamics of Verb-Particle Constructions: An Eye-Tracking Study
肌肉、前庭和触觉刺激对梦境整合影响的比较研究	Peters, E.	PDF	N/A	A Comparative Study of Muscular, Vestibular, and Haptic Stimulation on Dream Incorporation
小鼠海马CA1区锥体神经元的一个子集学习稀疏的突触输入模式。	Shahul, A. K.	PDF	N/A	A subset of mouse hippocampus CA1 pyramidal neurons learns sparse synaptic input patterns.
在有或没有视觉刺激的情况下，视觉皮层各区域间的逐次交互作用	Hidalgo, D.	PDF	N/A	Trial-by-trial inter-areal interactions in visual cortex in the presence or absence of visual stimulation
大脑反应的持续时间各不相同——建模策略与挑战	Skukies, R. S.	PDF	N/A	Brain responses vary in duration - modelingstrategies and challenges
访问TIL衍生的CD8 T细胞在可切除的HBV-HCC患者中抑制肿瘤复发的能力	Kah, J.	PDF	N/A	Accessing the specific capacity of TIL-derived CD8 T-cells to suppress tumor recurrence in resectable HBV-HCC patients
Cited4a限制了斑马鱼心脏再生过程中心肌细胞的去分化和增殖	Forman-Rubinsky, R.	PDF	N/A	Cited4a limits cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration
扩散进化只能从气候变化中拯救有限数量的物种	Kamal, P.	PDF	N/A	Dispersal evolution can only rescue a limited set of species from climate change
ActinoMation：一种用于中通量链霉菌属机器人接合的文学编程方法	Moeller, T. A.	PDF	N/A	ActinoMation: a literate programming approach for medium-throughput robotic conjugation of Streptomyces spp.
用于组成性高通量测序数据差异丰度检验的评分匹配方法	Ostner, J.	PDF	N/A	Score matching for differential abundance testing of compositional high-throughput sequencing data
NicheTrans：空间感知的多组学翻译	Wang, Z.	PDF	N/A	NicheTrans: Spatial-aware Cross-omics Translation
通过活性噪声对细胞质粘度的超灵敏调控	Zhao, Z.	PDF	N/A	Ultrasensitive tuning of cytoplasmic viscosity via active noise
白细胞介素-4诱导CD11c+小胶质细胞，从而改善小鼠的神经性疼痛	Kohno, K.	PDF	N/A	Interleukin-4 induces CD11c+ microglia leading to amelioration of neuropathic pain in mice
高分辨率运动学方法用于量化肌营养不良斑马鱼幼体的运动障碍	Widrick, J. J.	PDF	N/A	High resolution kinematic approach for quantifying impaired mobility of dystrophic zebrafish larvae
水稻叶片超疏水性的结构、遗传和适应性基础	Hiraiwa, A.	PDF	N/A	Structural, genetic, and adaptive basis of superhydrophobicity in rice leaves
印度和坦桑尼亚大规模现场研究中的脑电数据质量	Vianney, S. J.-M.	PDF	N/A	EEG data quality in large scale field studies in India and Tanzania
在人类和非人类灵长类动物中发现了与疫苗介导的结核病保护相关的体液相关性	Kelkar, N. S.	PDF	N/A	Humoral correlate of vaccine-mediated protection from tuberculosis identified in humans and non-human primates
人类参考基因集中有超过2,500个编码基因的状态仍未确定。	Maquedano, M.	PDF	N/A	More than 2,500 coding genes in the human reference gene set still have unsettled status
视网膜节细胞类型中与胆碱能视网膜波破坏相关的转录组变化	Somaiya, R. D.	PDF	N/A	Transcriptomic changes in retinal ganglion cell types associated with the disruption of cholinergic retinal waves
为动态GABA编辑的磁共振波谱数据进行稳健的时间子采样建模：考虑射击间变异性	Craven, A. R.	PDF	N/A	Modelling inter-shot variability for robust temporal sub-sampling of dynamic, GABA-edited MR spectroscopy data
大型效应生命史基因组区域与大西洋鲑的功能形态特征相关	Aykanat, T.	PDF	N/A	Large effect life-history genomic regions are associated with functional morphological traits in Atlantic salmon
红藻UV性染色体的结构和进化特征	Lipinska, A. P.	PDF	N/A	Structural and evolutionary features of red algal UV sex chromosomes
微小RNA的协同缺失揭示了啮齿动物基因调控的多层次重构	Langschied, F.	PDF	N/A	Concerted loss of micro-RNAs uncovers multi-level restructuring of gene regulation in rodents
真菌毒素和草甘膦残留对欧洲黇鹿肠道微生物群及抗性组的影响	Toth, A. G.	PDF	N/A	Impact of Mycotoxins and Glyphosate residue on the Gut Microbiome and Resistome of European Fallow Deer
鸽子对注视的跟随行为随着示范者数量的增加而增加。	Delacoux, M.	PDF	N/A	Gaze Following in Pigeons Increases with the Number of Demonstrators
BioMedGraphica：一个集成的平台，用于生物医学先验知识和组学信号图生成	Zhang, H.	PDF	N/A	BioMedGraphica: An All-in-One Platform for Biomedical Prior Knowledge and Omic Signaling Graph Generation
Gfa2bin通过将基因组图转换为泛基因组基因型，实现了基于图的GWAS（全基因组关联分析）。	Vorbrugg, S.	PDF	N/A	Gfa2bin enables graph-based GWAS by converting genome graphs to pan-genomic genotypes
单分子生物剂量测定法	Lamontagne, M.	PDF	N/A	Single-molecule biodosimetry
一种利用多物种基因组模型和基于原生质体的宏量并行报告基因分析来调控植物基因表达的可扩展方法	Jevtic, S.	PDF	N/A	A scalable method for modulating plant gene expression using a multispecies genomic model and protoplast-based massively parallel reporter assay
单体/二聚体开关调节植物腺苷激酶的活性。	Kopecny, D. J.	PDF	N/A	The monomer/dimer switch modulates the activity of plant adenosine kinase
《一百个神经网络与大脑观看视频：从对齐中汲取的教训》	Sartzetaki, C.	PDF	N/A	One Hundred Neural Networks and Brains Watching Videos: Lessons from Alignment
使用滞后希尔伯特自相关法对神经节律性进行多尺度参数化	Zhang, S.	PDF	N/A	Multi-scale parameterization of neural rhythmicity with lagged Hilbert autocoherence
使用滞后希尔伯特自相关对神经节律性进行多尺度参数化	Zhang, S.	PDF	N/A	Multi-scale parameterization of neural rhythmicity with lagged Hilbert autocoherence
deepBlastoid：一种基于深度学习的高通量分类器，用于使用明场图像对人类囊胚进行分类，并附带置信度评估	Fan, Z.	PDF	N/A	deepBlastoid: A Deep Learning-Based High-Throughput Classifier for Human Blastoids Using Brightfield Images with Confidence Assessment
单细胞数据的系统发育动力学推断	Dieselhorst, T.	PDF	N/A	Phylodynamic inference on single-cell data
酶调控的非热波动增强配体扩散和受体介导的内吞作用	Nividha,	PDF	N/A	Enzyme-Regulated Non-Thermal Fluctuations Enhance Ligand Diffusion and Receptor-Mediated Endocytosis
心肌细胞STIM1下调通过失调线粒体超微结构和代谢信号，加剧心肌梗死后重塑	Cacheux, M.	PDF	N/A	Cardiomyocyte STIM1 downregulation exacerbates post-Myocardial Infarction remodeling by dysregulating mitochondrial ultrastructure and metabolic signaling
鉴定非洲爪蟾胚胎组织中的类脑功能信息架构。	Varley, T.	PDF	N/A	Identification of brain-like functional information architectures in embryonic tissue of Xenopus laevis.
朊病毒疾病的二价siRNA	Gentile, J. E.	PDF	N/A	Divalent siRNA for prion disease
使用交互式视觉语言系统对行走环境的自我中心感知	Tan, H.	PDF	N/A	Egocentric perception of walking environments using an interactive vision-language system
与tau蛋白过度磷酸化相关的老年猕猴内嗅皮层钙信号失调。	Bathla, S.	PDF	N/A	Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation.
古代沉积物中的DNA显示，在格兰德提顿国家公园，海狸连续居住了超过5000年。	Baker, D. N.	PDF	N/A	Ancient sedimentary DNA shows more than 5000 years of continuous beaver occupancy in Grand Teton National Park
萨马科尾矿坝灾难发生六年后植物的招募：对物种丰富度和植物生长的影响	Paz, A. A.	PDF	N/A	Plant recruitment six years after the Samarcos tailings-dam disaster: Impacts on species richness and plant growth
微粒局部递送生长因子调控体外鸡胚骨模型中依赖生长因子的成骨和成软骨基因表达。	Rashidi, H.	PDF	N/A	Localized Delivery of Growth Factors from Microparticles Modulate Osteogenic and Chondrogenic Gene Expression in Growth Factor-dependent Manner in an ex vivo Chick Embryonic Bone Model.
定义SARS-CoV-2刺突糖蛋白受体结合基序中高度保守的B细胞表位	Malladi, S. K.	PDF	N/A	Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein
罗氏菌属新种Rhodococcus parequi sp. nov.，是从马场土壤中分离得到的一种新种，与病原菌Rhodococcus equi密切相关。	Vazquez-Boland, J. A.	PDF	N/A	Rhodococcus parequi sp. nov., a new species isolated from equine farm soil closely related to the pathogen Rhodococcus equi.
人乳微生物组宏基因组检测方法的优化	Zhang, Q.	PDF	N/A	Optimization of metagenomic detection method for human breast milk microbiome
细菌的Site 2蛋白酶通过靶向噬菌体裂解蛋白，在抵抗RNA噬菌体中发挥作用。	Bae, H.-W.	PDF	N/A	A bacterial site 2 protease contributes to RNA phage resistance by targeting phage lysis protein
冷冻电镜解析了古菌双链DNA病毒HFTV1从头部到尾部的结构。	Zhang, D. X.	PDF	N/A	Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
mRNA从核糖体中释放出来并配对作为单向正向旁路跳跃的驱动力的证据：其停止允许反向扫描。	Atkins, J.	PDF	N/A	Evidence for the pairing of mRNA exiting ribosomes acting as a Driver of unidirectional forward bypassing: Its cessation permits Backwards scanning
章鱼中的Z染色体剂量补偿与一种雄性特异性长链非编码RNA	Papanicolaou, N.	PDF	N/A	Z-chromosome dosage compensation and a male-specific lncRNA in octopus
结构更多，精度更少：ESM3的结合预测悖论	Loux, T.	PDF	N/A	More Structures, Less Accuracy: ESM3's Binding Prediction Paradox
XPG-DNA损伤结合动态的调控：由切刻前和切刻后核酸切除修复因子和EXO1共同参与	Muniesa-Vargas, A.	PDF	N/A	Regulation of XPG-DNA damage binding dynamics by pre- and post-incision nucleotide excision repair factors and EXO1
XRN1 提供游离核苷酸，以支持阿尔法病毒的复制过程。	Ruscica, V.	PDF	N/A	XRN1 supplies free nucleotides to feed alphavirus replication
DDI-GPT：利用知识图谱增强的大型语言模型进行药物-药物相互作用的解释性预测	Xu, C.	PDF	N/A	DDI-GPT: Explainable Prediction of Drug-Drug Interactions using Large Language Models enhanced with Knowledge Graphs
SARS-CoV-2刺突蛋白进化的综合分析：表位分类与免疫逃逸预测	Teruel, N. F. B.	PDF	N/A	Comprehensive Analysis of SARS-CoV-2 Spike Evolution: Epitope Classification and Immune Escape Prediction
DNA复制介导的双组分调控系统激活作为Burkholderia thailandensis的一种对冲策略	Lowrey, L. C.	PDF	N/A	DNA duplication-mediated activation of a two-component regulatory system serves as a bet-hedging strategy for Burkholderia thailandensis
爱沙尼亚人群肠道古菌收集	Pantiukh, K.	PDF	N/A	Human gut archaea collection from Estonian population
群体感应调节的小RNA Lrs1参与了铜绿假单胞菌对低铁环境的适应。	Panagiotopoulou, D.	PDF	N/A	The Quorum Sensing regulated sRNA Lrs1 is involved in the adaptation to low iron in Pseudomonas aeruginosa
PqsE作为铜绿假单胞菌特异性LuxR型受体调节器的演变：来自假单菌属和伯克霍尔德菌属的启示	Paczkowski, J. E.	PDF	N/A	Evolution of PqsE as a Pseudomonas aeruginosa-specific regulator of LuxR-type receptors: insights from Pseudomonas and Burkholderia
无肠海生蠕虫硫酸盐还原共生体的基因组和蛋白质组特征	D'Angelo, G.	PDF	N/A	Genomic and proteomic characterization of sulfate-reducing symbionts of gutless marine annelids
噪声暴露前后大鼠尿液蛋白质组的变化	Yang, M.	PDF	N/A	Changes in urinary proteome of rats before and after noise exposure
转录组分析揭示了新品种豚鼠肌肉肥大的MSTN突变及机制	Carmen, S.	PDF	N/A	Transcriptomic Analysis Reveals MSTN Mutations and Mechanisms of Muscle Hypertrophy in a New Guinea Pig Breed
转录因子与NIPBL/MAU2形成三元复合物，以在增强子上定位cohesin。	Fettweis, G.	PDF	N/A	Transcription factors form a ternary complex with NIPBL/MAU2 to localize cohesin at enhancers
通过单细胞RNA测序在三刺鱼中识别的不同细胞类型的进化速率存在差异。	Rodgers, M. L.	PDF	N/A	Rates of evolution differ between cell types identified by single-cell RNAseq in threespine stickleback
非典型结构与功能：来自Additional Sex Combs-like蛋白的PHD结构域	Reddington, C. J.	PDF	N/A	Unconventional structure and function of PHD domains from Additional Sex Combs-like proteins
CECR2溴结构域展现出对乙酰化组蛋白与非组蛋白配体不同的结合模式。	Phillips, M.	PDF	N/A	The CECR2 bromodomain displays distinct binding modes to select for acetylated histone proteins versus non-histone ligands.
基于动力学和结构的比较：沉默型鞭毛蛋白与刺激型鞭毛蛋白与TLR5的相互作用	Bell, M. E. W.	PDF	N/A	Kinetic and structure-based comparisons of silent and stimulatory flagellin interactions with TLR5
黏蛋白在流感病毒抑制中的结构决定因素：唾液酸化糖类与分子大小的协同作用	Butnarasu, C.	PDF	N/A	Structural Determinants of Mucins in Influenza Virus Inhibition: The Synergistic Role of Sialylated Glycans and Molecular Size
通过单电子氧化实现手性选择性光酶催化C(sp3)-H功能化	Zhu, J.	PDF	N/A	Enantioselective photoenzymatic C(sp3)-H functionalization via single-electron oxidation of carbanions
工程酵母中提取的必需固醇可防止蜜蜂群体数量下降	Moore, E. V.	PDF	N/A	Essential sterols from engineered yeast prevent honeybee colony population decline
实证研究表明，转移性喂养能提高地面筑巢鸟类的生产力。	Bamber, J. A.	PDF	N/A	Empirical evidence that diversionary feeding increases productivity in ground-nesting birds.
在人工环境中通过调整环境条件实现造礁珊瑚的“非季节性”产卵	Koukoumaftsis, L. P.	PDF	N/A	Controlled 'out-of-season' spawning of reef-forming corals in aquaria using offset environmental profiles
极度濒危的阿拉伯剑羚（Gazella arabica acacia）饮食策略的保育意义	Lavie, N.	PDF	N/A	Conservation implications of dietary strategies in the critically endangered Acacia gazelle (Gazella arabica acacia)
基于凝集素的天然糖RNA的简单快速检测	Li, Y.	PDF	N/A	Simple and rapid lectin-based detection of native glycoRNAs
鸣禽在东喜马拉雅混种鸟群中处于更核心的地位。	Gupta, S.	PDF	N/A	Vocal species are more central in Eastern Himalayan Mixed-Species bird flocks
共生效应、产卵不同步以及混合繁殖模式在常见的大规模产卵珊瑚中	Ricardo, G. F.	PDF	N/A	Allee effects, spawning asynchrony, and mixed reproductive modes in a common mass spawning coral
# BioRxiv 2024-12-08 Papers

标题	作者	PDF链接	代码仓库	Title
个体间在皮层组织的感觉运动-关联轴上的差异具有独特的遗传基础	Bignardi, G.	PDF	N/A	Distinct genetic underpinnings of inter-individual differences in the sensorimotor-association axis of cortical organisation
RNA结合蛋白IMP1/ZBP1驱动Actb mRNA在微胶质细胞外周突起中的定位和局部翻译，并介导形态变化、运动性和吞噬作用以响应炎症	Imaz-Iruretagoyena, J.	PDF	N/A	RNA binding protein IMP1/ZBP1 drives Actb mRNA localization and local translation in microglial peripheral processes and mediates morphological changes, motility and phagocytosis in response to inflammation
保守的3'茎环结构使我们能够在宏基因组中全面分析细菌转录终止，无论是否依赖Rho因子	Jin, Y.	PDF	N/A	Conserved 3' Stem-Loop Structures Enable Comprehensive Analysis of Bacterial Transcription Termination in Metagenomes, Regardless of Rho Factor Dependency
通过快速突触变化实现的简单句法规则	Sun, L.	PDF	N/A	Simple syntactic rules through rapid synaptic changes
miRTarDS：利用Sentence-BERT从预测数据库中高精度提炼蛋白质水平的微RNA目标相互作用	Chen, B.	PDF	N/A	miRTarDS: High-Accuracy Refining Protein-level MicroRNA Target Interactions from Prediction Databases Using Sentence-BERT
微囊藻中标记基因及细胞内无定形碳酸钙生物矿化候选基因表达的昼夜变化	Bruley, A.	PDF	N/A	Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis
值班爸爸：斑胸草雀首次孵卵记录	Scheiber, I. B. R.	PDF	N/A	Dads on duty: First account of nest sitting in barnacle ganders
谱系限制的机制基础	Wu, B.	PDF	N/A	Mechanistic basis of lineage restriction
每月对大型藻类的调查显示，城市潮间带区域存在着一个多样且动态的生物群落。	Schenk, S.	PDF	N/A	Monthly macroalgal surveys reveal a diverse and dynamic community in an urban intertidal zone
淀粉样前体蛋白（Amyloid Beta Precursor Protein）在短命的蓝绿光鳉鱼（Nothobranchius furzeri）中促进了脑衰老和学习能力的下降。	de Bakker, D. E. M.	PDF	N/A	Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)
对蝾螈Y染色体更替的鉴定未能支持Triturus平衡致死系统起源于性染色体	France, J. M.	PDF	N/A	Identification of Y-chromosome turnover in newts fails to support a sex chromosome origin for the Triturus balanced lethal system
在胚胎关键期，线粒体活性氧和HIF1-α信号的保守作用指导了后续神经系统发育。	Sobrid-Camean, D.	PDF	N/A	Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development
内耳神经元脱层的时间决定了它们的地形和目标神经支配	Saini, S. S. J. S.	PDF	N/A	Timing of delamination of inner ear neurons specifies their topography and target innervation
细菌计数时连续稀释过程中样本体积传递与传递次数之间的权衡	Jain, M.	PDF	N/A	Trade-off between sample volume passaged and number of passages involved during serial dilution for bacterial enumeration
人巨细胞病毒全病毒蛋白质组学揭示gpUL141是一种病毒颗粒成分，通过调节包膜糖蛋白组成以抵御体液免疫	Bentley, K.	PDF	N/A	Whole Virion Proteomics of HCMV Reveals that gpUL141 is a Virion Component that Regulates Envelope Glycoprotein Composition to Protect Against Humoral Immunity
葡萄糖感应ChREBP蛋白在糖尿病视网膜病变发病机制中的作用	Starr, C. R.	PDF	N/A	Glucose-Sensing ChREBP Protein in the Pathogenesis of Diabetic Retinopathy
自愿行动能增强感官预测，并促进对相关感官刺激的神经处理。	Ody, E.	PDF	N/A	Voluntary action sharpens sensory prediction and facilitates neural processing of contingent sensory stimuli
个性预测在新栖息地中的扩散和定居——一项中尺度实验	Gismann, J.	PDF	N/A	Personality predicts dispersal and settlement in a novel habitat - a mesocosm experiment
北极星：人类群体中扩展单倍型纯合性推断的祖先和衍生多态等位基因的极化。	Lisi, A.	PDF	N/A	Polaris: Polarization of ancestral and derived polymorphic alleles for inferences of extended haplotype homozygosity in human populations.
腹侧被盖区GABA神经元整合正负效价	Stelzner, M. E.	PDF	N/A	Ventral tegmental area GABA neurons integrate positive and negative valence
GABA能杏仁核神经元中的HCN1通道支撑着偏向雄性的攻击行为	Li, K.	PDF	N/A	HCN1 channels in GABAergic amygdalar neurons underpin male-biased aggressive behaviors
通过磁共振成像组织学表征的黑猩猩大脑寿命轨迹	Lipp, I.	PDF	N/A	Lifespan trajectory of chimpanzee brains characterized by magnetic resonance imaging histology
Pcdh15在内耳毛细胞内在极性发育中的作用	Kaushik, R.	PDF	N/A	Role Of Pcdh15 In The Development Of Intrinsic Polarity Of Inner Ear Hair Cells
空间单细胞细胞器组学揭示了营养依赖的肝细胞异质性，并预测了体内的病理生理状态	Hillsley, A.	PDF	N/A	Spatial single-cell Organellomics reveals nutrient dependent hepatocyteheterogeneity and predicts pathophysiological status in vivo
单细胞分析揭示了B细胞发育的多方面特征，以及与年龄相关的B细胞亚群	Yang, X.	PDF	N/A	Single-cell analysis reveals multi-faceted features of B cell development together with age-associated B cell subpopulations
高尔基体中谷胱甘肽氧化还原状态的表征	Miro-Vinyals, C.	PDF	N/A	Characterization of the Glutathione Redox State in the Golgi Apparatus
储存操作的钙离子进入参与了肺血管内皮细胞中的内皮间质转化	Babicheva, A.	PDF	N/A	Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells
FNBP4介导的非中心体形成蛋白FMN1在肌动蛋白细胞骨架动态调控中的机制性见解	Das, S.	PDF	N/A	Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics
MuSpAn：一个多尺度空间分析工具箱	Bull, J. A.	PDF	N/A	MuSpAn: A Toolbox for Multiscale Spatial Analysis
SubCell: 用于显微镜的视觉基础模型捕捉单细胞生物学	Gupta, A.	PDF	N/A	SubCell: Vision foundation models for microscopycapture single-cell biology
从卵母细胞中分离和操控减数分裂纺锤体揭示了在不对称分裂过程中由牵引力调控的迁移	Liu, N.	PDF	N/A	Isolation and manipulation of meiotic spindles from mouse oocytes reveals migration regulated by pulling force during asymmetric division
染色质压缩遵循幂律缩放规律，从间期到有丝分裂期间，其与细胞大小成比例变化。	Stockinger, P.	PDF	N/A	Chromatin Compaction Follows a Power Law Scaling with Cell Size from Interphase Through Mitosis
超分辨成像揭示了CD81微区在调节Jurkat T细胞微绒毛膜信号传导中的空间组织	Ramseier, N.	PDF	N/A	Superresolution Imaging Reveals the Spatial Organization of CD81 Microdomains in Regulating Membrane Signaling on Jurkat T Cell Microvilli
FAK活性通过VEGFR2-Cbl-NF-κB信号通路加剧了扰流介导的动脉粥样硬化。	Lim, S.	PDF	N/A	FAK activity exacerbates disturbed flow-mediated atherosclerosis via VEGFR2-Cbl-NF-κB signaling.
用于面部修复、再生和抗衰老的外泌体：不同商业产品之间的比较	Salvaggio, A.	PDF	N/A	Exosomes for facial repair, regeneration and rejuvenation: comparison between different commercial products
间充质干细胞/基质细胞向CD45+巨噬细胞样细胞的分化：拓展对MSC可塑性的认识	Rusch, R. M.	PDF	N/A	Differentiation of Mesenchymal Stem/ Stromal Cells into CD45+ Macrophage-like Cells: Expanding Insights into MSC Plasticity
肌修复过程中肌营养不良蛋白表达的时空分析	Hildyard, J. C. W.	PDF	N/A	Spatiotemporal analysis of dystrophin expression during muscle repair
普利帕斯汀是枯草芽孢杆菌在对抗镰刀菌属时共享的一种有益物质。	Stannius, R. O.	PDF	N/A	Plipastatin is a shared good by Bacillus subtilis during combating Fusarium spp.
细胞内RNA环状结构水平升高会抑制抗病毒反应。	Duan, C.	PDF	N/A	Elevated levels of intracellular RNA lariats suppress the antiviral response
去组蛋白修饰的Cas12a增强了单细胞CRISPR筛选	Snetkova, V.	PDF	N/A	Degron-modified Cas12a enhances single-cell CRISPR screening
人类遗传变异揭示FCRL3是淋巴细胞的鼠疫耶尔森菌受体	Keener, R.	PDF	N/A	Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis
Leucine Rich Repeat Kinase 2的Ras of Complex Proteins/GTPase结构域中的功能丧失性编码变异	Butterfield, S.	PDF	N/A	Loss-of-function coding variants in the Ras of Complex Proteins/GTPase domain of Leucine Rich Repeat Kinase 2
利用DMS MaP-Seq技术概念化核糖体mRNA解旋	Kellenberger, P.	PDF	N/A	Conceptualizing Ribosomal mRNA Unwinding Utilizing DMS MaP-Seq
细胞修饰tRNALys3的氨酰化的人类赖氨酰-tRNA合成酶的结构基础	Devarkar, S. C.	PDF	N/A	Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase
评估HGNC中人类非编码RNA命名的稳健性	Prasetyo, N. K.	PDF	N/A	Assessing the robustness of human ncRNA notation at HGNC
基于HSV-1基因组维持的HEK293细胞开发EASY-HSV（高效且简单的高产单纯疱疹病毒载体）系统	Maeda, F.	PDF	N/A	Development of the EASY-HSV (Efficient And Simple high-Yield Herpes Simplex virus Vector) system based on HSV-1 genome-maintaining HEK293 cells
脂质纳米颗粒递送mRNA逆转溶酶体酸性脂肪酶缺乏症的病理发生于临床前模型中	Zadory, M.	PDF	N/A	Lipid-based nanoparticles deliver mRNA to reverse the pathogenesis of lysosomal acid lipase deficiency in a preclinical model
OMAnnotator：一种构建注释共识基因组序列的新方法	Bates, S.	PDF	N/A	OMAnnotator: a novel approach to building an annotated consensus genome sequence
ProkBERT PhaStyle：利用预训练基因组语言模型进行准确的噬菌体生活方式预测	Juhasz, J.	PDF	N/A	ProkBERT PhaStyle: Accurate Phage Lifestyle Prediction with Pretrained Genomic Language Models
体外调节基于肌动蛋白的活性组装的收缩性和变形模式：从二维活性网络到液晶液滴	Stam, S.	PDF	N/A	Tuning the contractility and deformation modes of active actin-based assemblies in vitro: from 2D active networks to liquid crystal drops
CCR7和细胞粘附分子在鸡胚发育中对B细胞迁移至法氏囊的调控	Brunner, M.	PDF	N/A	Regulation of B cell migration to the Bursa of Fabricius by CCR7 and cell adhesion molecules in chicken embryonic development
源自肉桂皮提取物的纳米杀菌剂：植物化学成分分析及其对水稻细菌性穗枯病的抗菌功效	Alsutan, Q. M.	PDF	N/A	Nanobactericides Derived from Cinnamon Bark Extract: Phytochemical Profiling and Antibacterial Efficacy Against Bacterial Panicle Blight in Rice
根际土壤微生物类群的活性可以预测根系定殖的成功与否。	Harris, J. E.	PDF	N/A	The activity of soil microbial taxa in the rhizosphere predicts the success of root colonization
人诱导多能干细胞衍生的肌肉细胞作为研究EDMD1发病机制的新模型。	Lisowska, M.	PDF	N/A	Human iPSCs-derived muscle cells as a new model for investigation of EDMD1 pathogenesis.
一码多用：用于修复热点外显子剪接突变的反义寡核苷酸	Duan, C.	PDF	N/A	One-Size-Fits-Many: Antisense oligonucleotides for rescuing splicing mutations in hotspot exons
透明质酸与新兴组织力学协同调控指尖再生	Mui, B. W. H.	PDF	N/A	Hyaluronic Acid and Emergent Tissue Mechanics Orchestrate Digit Tip Regeneration
没有证据表明蝴蝶的蛋白质组组成与其实际的温度极限和饮食生态位宽度有关。	Caron, F.	PDF	N/A	No evidence that proteome composition is associated with realised thermal limit and dietary niche breadth in butterflies
亚致死剂量的农药暴露会降低有益传粉者的交配率并扰乱其化学信号传递。	Derstine, N.	PDF	N/A	Sublethal pesticide exposure decreases mating and disrupts chemical signaling in a beneficial pollinator
减数分裂性染色体失活：果蝇属中的保守性	Avelino, C. C.	PDF	N/A	Meiotic Sex Chromosome Inactivation: conservation across the Drosophila genus
发现5mC特异性脱氨酶及其在碱基分辨率下超灵敏直接测序甲基化位点的应用。	Yang, W.	PDF	N/A	The discovery of 5mC-selective deaminases and their application to ultra-sensitive direct sequencing of methylated sites at base resolution.
SpatioMark：量化空间邻近性对细胞表型的影响	Iyengar, S. S.	PDF	N/A	SpatioMark: Quantifying the impact of spatial proximity on cell phenotype
建模并预测单细胞多基因扰动响应：scLAMBDA	Wang, G.	PDF	N/A	Modeling and predicting single-cell multi-gene perturbation responses with scLAMBDA
CASSIA能够在单细胞RNA测序数据中进行稳健、自动的细胞注释。	Xie, E.	PDF	N/A	CASSIA allows for robust, automated cell annotation in single-cell RNA-sequencing data
果蝇连接组中的并行与汇聚多感官级联	Betzel, R. F.	PDF	N/A	Parallel and converging multisensory cascades in the Drosophila connectome
利用FoxP2区分鸣禽发声学习中的直接和间接基底神经节通路	Jagannathan, A.	PDF	N/A	Using FoxP2 to Distinguish Direct and Indirect Basal Ganglia Pathways for Vocal Learning in Songbirds
# BioRxiv 2024-12-07 Papers

标题	作者	PDF链接	代码仓库	Title
利用深度领域自适应匹配从体内尖峰序列中重建电路连接性	Sheng, K.	PDF	N/A	Reconstructing Circuit Connectivity from in vivo Spike Trains Using Deep Domain-Adaptive Matching
典型想象者和无想象症者中的视觉心理意象：一项毫米级7-T fMRI研究	Liu, J.	PDF	N/A	Visual mental imagery in typical imagers and in aphantasia: A millimeter-scale 7-T fMRI study
音高并非螺旋：探究音乐音高在不同任务和经验中的结构	Marjieh, R.	PDF	N/A	Pitch is Not a Helix: Probing the Structure of Musical Pitch Across Tasks and Experience
用于研究果蝇联想学习的驱动线	Shuai, Y.	PDF	N/A	Driver lines for studying associative learning in Drosophila
BRAF抑制剂二聚体选择性和结合协同作用的机制	Clayton, J.	PDF	N/A	Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF inhibitors
通过个性化碱基编辑在iPSC衍生的神经元中建模和校正蛋白质构象疾病	Konishi, C. T.	PDF	N/A	Modeling and Correction of Protein Conformational Disease in iPSC-derived Neurons through Personalized Base Editing
通过共表达AsCas12a超变体、T7 RNA聚合酶和胞嘧啶碱基编辑器，改进了利什曼原虫的基础编辑和功能筛选。	May, N. H.	PDF	N/A	Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA Polymerase, and a cytosine base editor
一个反馈驱动的脑类器官平台能够实现自动维护和高分辨率神经活动监测。	Voitiuk, K.	PDF	N/A	A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring
细胞内口袋构象通过μ阿片受体决定信号传导	Cooper, D. A.	PDF	N/A	Intracellular pocket conformations determine signaling through the μ opioid receptor
果蝇腿部本体感受和外感受神经回路的差异	Lee, S.-Y. J.	PDF	N/A	Divergent neural circuits for proprioceptive and exteroceptive sensing of the Drosophila leg
细菌双链DNA病毒基因组图谱的探索揭示了在广泛镶嵌性中存在ANI差距	Ndovie, W.	PDF	N/A	Exploration of the genetic landscape of bacterial dsDNA viruses reveals an ANI gap amidst extensive mosaicism
SAUSI：一种用于测量社交回避与动机的综合测验	Grammer, J.	PDF	N/A	SAUSI: an integrative assay for measuring social aversion and motivation
降低腹内侧下丘脑（VMH）中神经元一氧化氮合酶（nNOS）的表达会增加雌性小鼠的体重和血糖水平，同时减少其体力活动。	Hirschberg, P. R.	PDF	N/A	Reducing neuronal nitric oxide synthase (nNOS) expression in the ventromedial hypothalamus (VMH) increases body weight and blood glucose levels while decreasing physical activity in female mice.
可解释的蛋白质-DNA相互作用通过结构-序列优化捕捉	Zhang, Y.	PDF	N/A	Interpretable Protein-DNA Interactions Captured by Structure-Sequence Optimization
竞争效应调节微小RNA池的组成	Raak, S. B.	PDF	N/A	Competition effects regulating the composition of the microRNA pool
解读情绪状态下内侧前额叶皮层下行通路中的隐藏变异性	Lai, C.-H.	PDF	N/A	Decoding the hidden variabilities in mPFC descending pathways across emotional states
海南岛非结核分枝杆菌的分布、流行及耐药性	Xu, X.	PDF	N/A	Distribution, Prevalence, and Antibiotic Resistance of Non-Tuberculous Mycobacteria on Hainan Island
支原体滑动运动的F1样ATP酶的二聚体组装	Toyonaga, T.	PDF	N/A	Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma
消费者体型和栖息地偏好对资源分布的空间指纹	Little, C. J.	PDF	N/A	Spatial fingerprint of consumer body size and habitat preference on resource distribution
朝着昆虫相机陷阱图像的边缘处理方向发展	Bjerge, K.	PDF	N/A	Towards edge processing of images from insect camera traps
平行HIV-1适应性景观塑造了人类和猕猴中病毒动力学，这些宿主能够产生广谱中和抗体。	Shimagaki, K. S.	PDF	N/A	Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies.
躯体感觉知觉的兴奋性调节并不依赖于前馈神经元群体的放电。	Stephani, T.	PDF	N/A	Excitability modulations of somatosensory perception do not depend on feedforward neuronal population spikes
条件序列-结构整合：一种用于精准抗体工程和亲和力优化的创新方法	Jamialahmadi, B.	PDF	N/A	Conditional Sequence-Structure Integration: A Novel Approach for Precision Antibody Engineering and Affinity Optimization
非周期性和振荡系统构成了人类领域一般认知的基础	Lu, R.	PDF	N/A	Aperiodic and oscillatory systems underpinning human domain-general cognition
PeakClimber：一种用于使用指数高斯函数精确量化复杂多分析物HPLC色谱图的软件工具	Derrick, J.	PDF	N/A	PeakClimber: A software tool for the accurate quantification of complex multianalyte HPLC chromatograms using the exponential Gaussian function
SOI：利用直系同源指数进行同线性基因组的鲁棒鉴定及其在进化基因组学中的广泛应用	Zhang, R.-G.	PDF	N/A	SOI: Robust identification of orthologous synteny with the Orthology Index and broad applications in evolutionary genomics
双光子NAD(P)H-FLIM显示，与宿主巨噬细胞在接触青蒿素衍生物后不同，猪蛔虫幼虫的能量代谢未受影响。	Musimbi, Z. D.	PDF	N/A	Two-Photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure
具身视角：角回和楔前叶在自然事件记忆中解码自我身份	Iriye, H.	PDF	N/A	An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events
血清素类迷幻药DOI会损害听觉皮层的异常检测能力	Horrocks, M.	PDF	N/A	The serotonergic psychedelic DOI impairs deviance detection in the auditory cortex
BindCraft：功能性蛋白质结合剂的一步设计	Pacesa, M.	PDF	N/A	BindCraft: one-shot design of functional protein binders
中性粒细胞表现出不同的迁移表型，这些表型受跨内皮迁移的调控。	Schwartz, A. B.	PDF	N/A	Neutrophils exhibit distinct migration phenotypes that are regulated by transendothelial migration
伏隔核D2表达神经元：通过节律性光遗传刺激平衡奖励与舔舐中断	Requejo-Mendoza, N.	PDF	N/A	Nucleus accumbens D2-expressing neurons: Balancing reward and licking disruption through rhythmic optogenetic stimulation
高吞吐量蛋白质组学和磷酸蛋白质组学分析的福尔马林固定石蜡包埋组织	Haines, M.	PDF	N/A	High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissue
寄生虫、宿主、猎物和环境之间的LINE-RTE逆转录转座子的水平转移。	Brann, T.	PDF	N/A	Horizontal transfer of a LINE-RTE retrotransposon among parasite, host, prey and environment.
编程群体组成和多细胞形态的合成比例计算	An, B.	PDF	N/A	Synthetic ratio computation for programming population composition and multicellular morphology
转录因子GATA1识别RNA的独特机制	Ugay, D. A.	PDF	N/A	A distinct mechanism of RNA recognition by the transcription factor GATA1
大豆（Glycine max. (L.) Merrill）品系表型形态特征及遗传多样性评估，以促进育种进展	Saha, M.	PDF	N/A	Pheno-Morphological Characterization and Genetic Diversity Assessment of Grain and Vegetable Soybean (Glycine max. (L.) Merrill) Lines for Breeding Advancements
单倍二倍体加速了昆虫线粒体基因组的进化	Pakrashi, A.	PDF	N/A	HAPLODIPLOIDY ACCELERATES MITOGENOME EVOLUTION IN INSECTS
RpiBeh：一种多用途的开源解决方案，用于实时追踪和基于行为驱动的啮齿动物神经行为学闭环干预	Sun, Y.	PDF	N/A	RpiBeh: a multi-purpose open-source solution for real-time tracking and behavior-driven closed-loop interventions in rodent neuroethology
冷冻电镜显示，源自心脏IGLV6的AL纤维可以具有多态性。	Bassett, P. T.	PDF	N/A	Cryo-EM reveals that cardiac IGLV6-derived AL fibrils can be polymorphic
科学出版物中定量聚合酶链反应（qPCR）方法的报告质量	Drude, N. I.	PDF	N/A	Reporting quality of quantitative polymerase chain reaction (qPCR) methods in scientific publications
你可以做到！利用已发表的关于水螅口部张开的本科生研究来训练本科生	Hackler, S.	PDF	N/A	You can do it! Using published undergraduate research on Hydra mouth opening to train undergraduates
Ozboneviz：澳大利亚在FAIR 3D影像和扩展生物多样性收藏方面的先例	Weisbecker, V.	PDF	N/A	Ozboneviz: An Australian Precedent in FAIR 3D Imagery and Extended Biodiversity Collections
符号和非符号数字在数字线二等分任务中对中心识别的影响不同	Porru, A.	PDF	N/A	Symbolic and Non-Symbolic numbers differently affect centre identification in a number-line bisection task
发作间期抑制性网络的崩溃允许癫痫发作扩散	Makhoul, G. S. P.	PDF	N/A	Collapse of Interictal Suppressive Networks Permits Seizure Spread
控制感能缓解压力	Fielder, J. C.	PDF	N/A	Sense of control buffers against stress
执行功能与更新预测表征之间的相互作用	Pedraza, F.	PDF	N/A	The interplay between executive functions and updating predictive representations
前扣带皮层损伤会破坏人类处理奖励的电生理特征	Oerlemans, J.	PDF	N/A	Lesions of anterior cingulate cortex disrupt an electrophysiological signature of reward processing in humans
外周免疫细胞对刺激的反应将帕金森病从前驱期到临床期的进展进行了分层	Mark, J. R.	PDF	N/A	Peripheral immune cell response to stimulation stratifies Parkinson's disease progression from prodromal to clinical stages
模拟驾驶环境中器乐对双任务干扰的影响	Khadiv, E.	PDF	N/A	The Impact of Instrumental Music on Dual-task Interference in a Simulated Driving Environment
ForestForward：可视化和访问过去五十年综合世界森林数据	Tejada-Gutierrez, E. L.	PDF	N/A	ForestForward: visualizing and accessing integrated world forest data from the last fifty years
接受个体化新抗原导向疫苗治疗的转移性癌症患者全面纵向ctDNA监测	Schenk, D.	PDF	N/A	Comprehensive Longitudinal ctDNA Monitoring in Metastatic Cancer Patients Treated with an Individualized Neoantigen-directed Vaccine
PISA：多功能3D单分子光片显微镜	Taniguchi, Y.	PDF	N/A	PISA: versatile microscope for 3D single molecule light sheet imaging
积雪草组织培养衍生的胞外囊泡：多角度应用于护肤领域	Chang, T.-M.	PDF	N/A	Centella asiatica Tissue Culture-Derived Extracellular Vesicles: A Multifaceted Approach to Skincare Applications
比较功能性和结构性神经影像数据中的个体内部和个体间相关脑连接性	Di, X.	PDF	N/A	Comparing Intra- and Inter-individual Correlational Brain Connectivity from Functional and Structural Neuroimaging Data
周围传入纤维对脊髓感觉输入的调节。寻找中继站	Slawinska, U.	PDF	N/A	Modulation of sensory input to the spinal cord by peripheral afferent fibres. Searching for relays
通过台式质谱仪进行多模态脂质-蛋白质-组织学成像，探索阿尔茨海默病小鼠中的Aβ斑块微环境	Mueller, E.	PDF	N/A	Exploring the Abeta Plaque Microenvironment in Alzheimer's Disease Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer
评估空间化声学场景中变化检测的行为和神经相关性	Poole, K. C.	PDF	N/A	Assessing Behavioral and Neural Correlates of Change Detection in Spatialized Acoustic Scenes
在果蝇翅膀上皮发育过程中，Frizzled1和Frizzled2在低Wingless水平下的竞争性生存中并非冗余。	Hingole, S.	PDF	N/A	Frizzled1 and Frizzled2 are not redundant for competitive survival under low-Wingless levels in the developing Drosophila wing epithelium
重新审视生物医学研究中的胚胎鸡模型：一个科学案例	McGrew, M. J.	PDF	N/A	A scientific case for revisiting the embryonic chicken model in biomedical research
ANKRD5：轴丝的一个关键组成部分，对精子运动和男性生育能力至关重要	Yu, S.	PDF	N/A	ANKRD5: a key component of the axoneme required for spermmotility and male fertility
通过血淋巴和环境DNA调查，在普吉特海湾的软壳蛤（Mya arenaria）中识别出双壳类可传播性肿瘤的暴发	Weinandt, S. A.	PDF	N/A	Identification of an Outbreak of Bivalve Transmissible Neoplasia in Soft-Shell Clams (Mya arenaria) in the Puget Sound Using Hemolymph and eDNA Surveys
圈养繁殖野兔的饮食干预未能使肠道微生物群富集具有野生功能的微生物	Aizpurua, O.	PDF	N/A	Dietary intervention in captive-bred hares fails to enrich gut microbiomes with wild-like functions
在非洲发现已驯化“迷幻蘑菇”Psilocybe cubensis 最亲近的野生近亲	Bradshaw, A. J.	PDF	N/A	Discovery of the closest free-living relative of the domesticated "magic mushroom" Psilocybe cubensis in Africa
基于TurboID的邻近标记技术鉴定出维持秀丽隐杆线虫E颗粒完整性和小RNA稳态的新型生殖系蛋白	Li, K.	PDF	N/A	TurboID-based proximity labeling identifies novel germline proteins that maintain E granule integrity and small RNA homeostasis in C. elegans
一种与腺苷淀粉样纤维形成相关的先天性代谢错误模型可减少TDP-43在酵母中的聚集和毒性	Park, S.	PDF	N/A	A model of inborn metabolism errors associated with adenine amyloid-like fiber formation reduces TDP-43 aggregation and toxicity in yeast
条纹田鼠（Apodemus agrarius）的ERGA-BGE参考基因组，该物种在欧洲中部和东部广泛分布且数量众多。	Janzekovic, F.	PDF	N/A	ERGA-BGE Reference Genome of the Striped Field Mouse (Apodemus agrarius), a Widespread and Abundant Species in Central and Eastern Europe
两种涉及EDN3的结构变异导致鸡的色素沉着过度	Ma, C.	PDF	N/A	Two distinct structural variants involving EDN3 cause hyperpigmentation in chicken
人类基因组在核DNA和无细胞DNA中的覆盖情况	Luo, J.	PDF	N/A	Coverage landscape of the human genome in nucleus DNA and cell-free DNA
乌干达和博茨瓦纳感染艾滋病毒的儿童中存在高KIR多样性	John, M.	PDF	N/A	High KIR diversity in Uganda and Botswana children living with HIV
通过超滤纯化环状RNA	Cuevas, K. d. J. G.	PDF	N/A	Purifying circular RNA by ultrafiltration
工程化人体淋巴结基质模型用于研究间质液流和T细胞外排	Hammel, J. H.	PDF	N/A	Engineered human lymph node stroma model for examining interstitial fluid flow and T cell egress
将无催化活性的RusA与FokI核酸酶融合，并结合PNA，可实现可编程的位点特异性双链DNA断裂	Mahfouz, M.	PDF	N/A	Fusions of catalytically inactive RusA to FokI nuclease coupled with PNA enable programable site-specific double-stranded DNA breaks
调整组织模板及其细胞居民的机械环境，以指导机械适应性	Putra, V. L.	PDF	N/A	Tuning mechanical milieux of tissue templates and their cellular inhabitants to guide mechanoadaptation
Protein2Text：为蛋白质序列提供丰富的描述	Dotan, E.	PDF	N/A	Protein2Text: Providing Rich Descriptions for Protein Sequences
癌症药物反应建模：蛋白质组学与转录组学的对比	Zheng, Z.	PDF	N/A	Drug Response Modeling across Cancers: Proteomics vs. Transcriptomics
预测和注释鸡基因组中的替代转录起始位点和启动子移位	Grushina, V. A.	PDF	N/A	Prediction and annotation of alternative transcription starts and promoter shift in the chicken genome
使用网络聚类算法进行细胞类型分化	Fatemi Nasrollahi, F. S.	PDF	N/A	Cell Type Differentiation Using Network Clustering Algorithms
重复扩增障碍中CRISPR/Cas9靶向纳米孔测序方法的比较分析	Benarroch, L.	PDF	N/A	Comparative analysis of CRISPR/Cas9-targeted nanopore sequencing approaches in repeat expansion disorders
RIDDEN：从转录组数据中推断受体活性的数据驱动推理	Barsi, S.	PDF	N/A	RIDDEN: Data-driven inference of receptor activity from transcriptomic data
GraphVelo 允许推断多模态单细胞速度和分子机制	Chen, Y.	PDF	N/A	GraphVelo allows inference of multi-modal single cell velocities and molecular mechanisms
BindingGYM：一个大规模的突变数据集，旨在解析蛋白质-蛋白质相互作用	Lu, W.	PDF	N/A	BindingGYM: A Large-Scale Mutational Dataset Toward Deciphering Protein-Protein Interactions
用于生物组织定量光学特性和色团浓度图像的深度集成模型	Yan, B.	PDF	N/A	Deep Ensemble Model for Quantitative Optical Property and Chromophore Concentration Images of Biological Tissues
金复合物Auranofin使耐铂的上皮性卵巢癌细胞对顺铂敏感	Abdalbari, F. H.	PDF	N/A	The gold complex auranofin sensitizes platinum resistant epithelial ovarian cancer cells to cisplatin
鹦形目中高密度和低密度脂蛋白胆固醇的血清脂质参考区间及其与动脉粥样硬化和其他因素的关联	Janeczek, M.	PDF	N/A	Serum lipid reference intervals of high-density and low-density lipoprotein cholesterols and their association with atherosclerosis and other factors in Psittaciformes
苯代谢物通过激活热休克蛋白和Rho GTPase来增加血管通透性。	Zelko, I. N.	PDF	N/A	Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases
蛇毒金属蛋白酶主要负责某些非洲蝰蛇毒液的细胞毒性作用。	Bartlett, K. E.	PDF	N/A	Snake venom metalloproteinases are predominantly responsible for the cytotoxic effects of certain African viper venoms
肾上腺皮质癌细胞对氧化铁纳米颗粒的摄取	Challapalli, R. S.	PDF	N/A	Adrenocortical Cancer Cell uptake of Iron Oxide Nanoparticles
ACKR3信号的淋巴激活调节缺血性心脏损伤后的淋巴反应。	Balint, L.	PDF	N/A	Lymphatic activation of ACKR3 signaling regulates lymphatic response after ischemic heart injury.
At-RS31 调控剪接因子的层级交叉调节，并将选择性剪接与TOR-ABA途径整合	Koster, T.	PDF	N/A	At-RS31 orchestrates hierarchical cross-regulation of splicing factors and integrates alternative splicing with TOR-ABA pathways
CAFE：一个综合性的网络应用程序，用于光谱流式细胞术中的高维度分析与可视化	Siam, M. H. B.	PDF	N/A	CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry
参考组织的同时多因素贝叶斯分析（SiMBA）在PET时间活动曲线数据中的实现	Matheson, G. J.	PDF	N/A	A Reference Tissue Implementation of Simultaneous Multifactor Bayesian Analysis (SiMBA) of PET Time Activity Curve Data
脑损伤后斑马鱼嗅觉系统的结构再生和功能恢复	Calvo-Ochoa, E.	PDF	N/A	Structural regeneration and functional recovery of the olfactory system of zebrafish following brain injury
亚精胺通过调节应激反应缓解抑郁	Mackert, S.	PDF	N/A	Spermidine alleviates depression via control of the stress response
小鼠方偏差：在规则修订模型中的审议决策揭示了小鼠中类似“我方”确认偏差的认知过程。	Stevens, C.	PDF	N/A	Mice-side bias: Deliberative decision making in a model of rule revision reveals 'myside' confirmation bias-like cognitive processes in mice.
皮层动力学在快速步态启动中的作用，涉及不同的姿势需求	Giesbers, I.	PDF	N/A	Cortical dynamics underlying initiation of rapid steps with contrasting postural demands
快感不足？幻觉倾向对积极自我语音感觉反馈处理的影响	Duggirala, S. X.	PDF	N/A	Not enough pleasure? Influence of hallucination proneness on sensory feedback processing of positive self-voice
从子宫到摇篮：胎儿在子宫内的活动模式如何揭示出生后的睡眠行为	Markovic, A.	PDF	N/A	From womb to crib: How fetal activity patterns in utero reveal postnatal sleep behavior
规模多样性、丰度和能量：生物多样性动态的平衡理论	Storch, D.	PDF	N/A	Scaling diversity, abundance and energy: the Equilibrium Theory of Biodiversity Dynamics
利用贝叶斯分层模型结合声学遥测、生物学和环境数据评估溯河性鲑科鱼类的存活率	Munaweera, I.	PDF	N/A	Estimating survival of an anadromous salmonid using Bayesian hierarchical models applied to acoustic telemetry, biological, and environmental data
通过谱系学视角看幻影上位	Ignatieva, A.	PDF	N/A	Phantom epistasis through the lens of genealogies
环境诱导的精子sRNA变异与斑马鱼后代的基因表达和转座元件相关	Godden, A. M.	PDF	N/A	Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring
在更新世乳齿象的边缘种群中，气候驱动的扩散和物种形成反复发生。	Karpinski, E.	PDF	N/A	Repeated climate-driven dispersal and speciation in peripheral populations of Pleistocene mastodons
生活在不同气候带的北极熊亚种群之间转座子活性差异	Godden, A. M.	PDF	N/A	Diverging transposon activity among polar bear sub-populations inhabiting different climate zones
在Podospora anserina中，MAT近端区域的遗传分化并不足以抑制重组	Grognet, P.	PDF	N/A	Genetic differentiation in the MAT-proximal region is not sufficient for suppressing recombination in Podospora anserina
色素沉着与视网膜色素上皮厚度：一项研究眼内与眼外色素组织表型与基因型关系的研究。	Julian, T. H.	PDF	N/A	Pigmentation and retinal pigment epithelium thickness: a study of the phenotypic and genotypic relationships between ocular and extraocular pigmented tissues.
一种模拟人类LDLR相关动脉粥样硬化的猫科动物模型	Hytonen, M. K.	PDF	N/A	A feline model of human LDLR-related atherosclerosis
大肠杆菌中补骨脂素-链间交联抗性的复杂发展需要AcrR失活、保留marbox序列以及MarA、SoxS或Rob全球调控因子中的一个。	Worley, T. K.	PDF	N/A	The complex development of psoralen-interstrand crosslink resistance in Escherichia coli requires AcrR inactivation, retention of a marbox sequence, and one of three MarA, SoxS, or Rob global regulators
功能基因组学验证PPARγ信号在肺动脉平滑肌细胞中的作用：对肺动脉高压治疗的启示	Su, R.	PDF	N/A	Functional Genomics Validation of PPAR gamma Signalling in PASMCs: Therapeutic Implications for Pulmonary Arterial Hypertension
埃及伊蚊全线粒体基因组分析揭示与沃尔巴克氏菌感染的关联	Gupta, B.	PDF	N/A	Whole mitochondrial genome analysis of Aedes aegypti reveal association with Wolbachia infection
预测多肽结构构象与AlphaFold2	Ille, A. M.	PDF	N/A	Prediction of peptide structural conformations with AlphaFold2
使用混合数据集中的二维电导率概率分布进行遗传序列识别的机器学习框架	Wang, Y.	PDF	N/A	A ML Framework for Genetic Sequence Identification using 2D Electrical Conductance Probability Distributions from Mixed Data Sets
GRU-SCANET：释放基于GRU的正弦捕获网络在精准命名实体识别中的潜力	Happi Happi, B. G.	PDF	N/A	GRU-SCANET: Unleashing the Power of GRU-based Sinusoidal CApture Network for Precision-driven Named Entity Recognition
体外β2肾上腺素受体刺激下BPH-1细胞的神经内分泌分化	PIGAT, N.	PDF	N/A	In vitro neuroendocrine differentiation of BPH-1 cells under beta2 adrenergic receptor stimulation
小鼠膀胱癌中多谱系肿瘤细胞群体的图谱绘制	Schrode, N.	PDF	N/A	Mapping of Multilineage Tumor Cell Populations in Mouse Bladder Cancer
SUMO抑制加上CD40激动剂通过干扰素介导的巨噬细胞激活增加了抗肿瘤免疫原性	Li, K. Y.	PDF	N/A	SUMO Inhibition Plus CD40 Agonism Increases Anti-Tumor Immunogenicity Through Interferon Mediated Macrophage Activation
在详细的皮层模型中，尖峰分类偏差和信息丢失	Laquitaine, S.	PDF	N/A	Spike sorting biases and information loss in a detailed cortical model
TRPM7活性以依赖镁的方式驱动人类CD4 T细胞的激活和分化	Madlmayr, A.	PDF	N/A	TRPM7 activity drives human CD4 T-cell activation and differentiation in a magnesium dependent manner
在组织工程平台上协同生成心脏驻留样巨噬细胞和心肌细胞成熟	Suku, M.	PDF	N/A	Synergistic generation of cardiac resident-like macrophages and cardiomyocyte maturation in tissue engineered platforms
破坏基底CXCR4寡聚体损害淋巴瘤中的致癌特性	Mobach, S.	PDF	N/A	Disruption of basal CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms
建立可靠的小鼠三甲胺N-氧化物状态血液生物标志物：口服胆碱挑战、饮食胆碱和禁食条件的影响	Din, A. U.	PDF	N/A	Establishing reliable blood biomarkers for trimethylamine N-oxide status in rodents: effects of oral choline challenge, dietary choline and fasting conditions
将多样化的生物活性数据整合到化学检查器化合物宇宙中	Comajuncosa-Creus, A.	PDF	N/A	Integration of diverse bioactivity data into the Chemical Checker compound universe
MerQuaCo：一种基于图像的空间转录组学质量控制计算工具	Martin, N. X.	PDF	N/A	MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics
布卡·德拉·伊纳和格罗塔·德尔·卡普里奥洛：对意大利中部两个晚期穆斯特文化遗址的新年代学、石器和动物群分析	Gennai, J.	PDF	N/A	Buca della Iena and Grotta del Capriolo: new chronological, lithic, and faunal analyses of two late Mousterian sites in Central Italy
果蝇中一种用于情境依赖的多模态信号传递的神经回路	Steinfath, E.	PDF	N/A	A neural circuit for context-dependent multimodal signaling in Drosophila
lenacapavir通过一种主要机制实现对HIV-1成熟过程的高度有效抑制。	Huang, S.-W.	PDF	N/A	The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir
鱼精蛋白的抗真菌活性	Kumarasamy, A.	PDF	N/A	Antifungal activity of protamine
植物来源的代谢物与根际微生物群功能的相互作用增强了干旱胁迫耐受性	Kazarina, A.	PDF	N/A	Interaction of plant-derived metabolites and rhizobiome functions enhances drought stress tolerance
基质孔隙度与假体关节感染期间金黄色葡萄球菌生物膜的存活有关。	Bhattacharya, M.	PDF	N/A	Matrix porosity is associated with Staphylococcus aureus biofilm survival during prosthetic joint infection
在B族链球菌中进行的CRISPRi文库筛选鉴定出表面免疫原性蛋白（Sip）作为多种宿主相互作用的中介因子。	Firestone, K.	PDF	N/A	A CRISPRi Library Screen in Group B Streptococcus Identifies Surface Immunogenic Protein (Sip) as a Mediator of Multiple Host Interactions
施肥对草地食物链中的微生物群落产生影响	Jetter, K.	PDF	N/A	Fertilization impacts microbiomes along the grassland trophic chain
敲除仅在排泄腺细胞中表达的所有线虫特异性NSPC基因，会导致转录组特征表明胰岛素信号传导受到影响。	Mackiewicz, Z.	PDF	N/A	Knockout of all nematode-specific NSPC genes expressed exclusively in the excretory gland cell results in transcriptomic signatures indicating an affected insulin signaling
PER2蛋白表达减少导致β1-AA诱导的心脏自噬节律紊乱	Li, P.	PDF	N/A	Reduced expression of PER2 protein contrbutes to β1-AA induced cardiac autophagy rhythm disorder
不同相互作用类型的生态网络在生物地理尺度上具有模块性，并且高度依赖于采样强度。	Garcia-Callejas, D.	PDF	N/A	Ecological networks across interaction types are modular and highly driven by sampling intensity at biogeographical scales
蛋白质进化中的波动与可预测性极限	Rossi, S.	PDF	N/A	Fluctuations and the limit of predictability in protein evolution
一般人群中的亲代间基因转换：一种新的杂合性丧失机制	Toratani, J.	PDF	N/A	Interparental Gene Conversion in General Population: A Novel Mechanism For Loss of Heterozygosity
一氧化氮通过Rab5的S-亚硝基化调节吞噬作用	Hagiwara, M.	PDF	N/A	Nitric oxide regulates phagocytosis through S-nitrosylation of Rab5
基于大环降解剂BTR2004对CUL3KLHL20驱动的BET家族BRD蛋白靶向降解的时间和空间特性研究	Yeh, J.	PDF	N/A	Temporal and Spatial Characterization of CUL3KLHL20-driven Targeted Degradation of BET family, BRD Proteins by the Macrocycle-based Degrader BTR2004
设计白细胞介素-21模拟物的强大抗癌活性	Chun, J.-H.	PDF	N/A	Potent antitumor activity of a designed interleukin-21 mimic
用于冷冻电镜和冷冻电子断层扫描中方向估计的贝叶斯视角	Xu, S.	PDF	N/A	Bayesian Perspective for Orientation Estimation in Cryo-EM and Cryo-ET
由NKX2-1调控的表观遗传重塑和三维染色质重构推动神经内分泌前列腺癌的发展。	Lu, X.	PDF	N/A	Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancer
发现新型选择性GPR17拮抗剂作为开发糖尿病和肥胖症新治疗策略的药理工具	Zhu, H.	PDF	N/A	Discovery of Novel and Selective GPR17 Antagonists as Pharmacological Tools for Developing New Therapeutic Strategies in Diabetes and Obesity
小麦白粉病菌（Zymoseptoria tritici）的隐匿感染是通过阶段特异性下调β-葡聚糖酶来实现的。	Rebaque, D.	PDF	N/A	Zymoseptoria tritici stealth infection is facilitated by stage-specific down-regulation of a β-glucanase
陆生植物中果胶裂解酶样基因的进化及其在寄生植物吸器形成中的作用	Zhang, H.	PDF	N/A	The evolution of pectate lyase-like genes across land plants, and their roles in haustorium formation in parasitic plants
一步法生物催化级联反应从醛或羧酸制备多种L-苯丙氨酸衍生物	Anderson, S. R.	PDF	N/A	A One-Pot Biocatalytic Cascade to Access Diverse L-Phenylalanine Derivatives from Aldehydes or Carboxylic Acids
MCSPACE：从高通量共定位数据推断微生物组的时空动态	Uppal, G.	PDF	N/A	MCSPACE: inferring microbiome spatiotemporal dynamics from high-throughput co-localization data
家庭环境中的病原体和抗菌药物耐药基因：孟加拉国农村土壤地板和牛粪研究	Nguyen, A. T.	PDF	N/A	Pathogens and Antimicrobial Resistance Genes in Household Environments: A Study of Soil Floors and Cow Dung in Rural Bangladesh
全基因组分析大肠杆菌对次硫氰酸盐胁迫的响应，揭示RclB和RclC可能降低细胞膜通透性的作用	Meredith, J. D.	PDF	N/A	Genome-wide characterization of hypothiocyanite stress response of Escherichia coli reveals a potential role for RclB and RclC in lowering cell envelope permeability
通过HIV-1编码的反义转录本实现表观遗传沉默及潜伏逆转的阻断	Li, R.	PDF	N/A	Epigenetic silencing and blockade of latency reversal by an HIV-1 encoded antisense transcript
成年蜂王食用花粉和花蜜。	St. Clair, A.	PDF	N/A	Adult honey bee queens consume pollen and nectar
# BioRxiv 2024-12-06 Papers

标题	作者	PDF链接	代码仓库	Title
图像平衡是一种自下而上的神经美学特性，介导着注意力和眼球运动。一个原始的视觉操作系统解释了平衡的属性，以及一种基本的视觉组织世界的方式。	Corwin, D. M.	PDF	N/A	Pictorial balance is a bottom-up neuro-aesthetic property mediating attention and eye movements. A primitive visual operating system explains the property of balance and a primary visual way of organizing the world.
端粒酶依赖性斑马鱼大脑衰老	Martins, R. R.	PDF	N/A	Telomerase-Dependent Ageing In The Zebrafish Brain
有丝分裂神经母细胞的检测为成年小肠肌间神经丛中持续的神经发生提供了额外证据。	Gorecki, A. M.	PDF	N/A	Detection of mitotic neuroblasts provides additional evidence of steady state neurogenesis in the adult small intestinal myenteric plexus
TriScan：采用简单光学设计的快速、高灵敏度三维共聚焦荧光成像技术	Van den Eynde, R.	PDF	N/A	The TriScan: fast and sensitive 3D confocal fluorescence imaging using a simple optical design
神经活动跨学科映射与受限玻尔兹曼机	Yang, H.	PDF	N/A	Cross-subject Mapping of Neural Activity with Restricted Boltzmann Machines
依赖于偏心率的扫视反应时间：中央凹放大和注意定向的作用	Zhang, Y.	PDF	N/A	Eccentricity-Dependent Saccadic Reaction Time: The Roles of Foveal Magnification and Attentional Orienting
神经网络在认知任务期间被调整至接近临界状态，而在阿尔茨海默病的精神药理学模型中则远离临界状态	Habibollahi, F.	PDF	N/A	Neural Networks Are Tuned Near Criticality During a Cognitive Task and Distanced from Criticality In a Psychopharmacological Model of Alzheimer's Disease
在季节性缩小的过程中，白足鼩鼱的动态代谢和分子变化	Thomas, W. R.	PDF	N/A	Dynamic metabolic and molecular changes during seasonal shrinking in Sorex araneus
硬骨鱼类幼体中多样的捕食策略	Mearns, D. S.	PDF	N/A	Diverse prey capture strategies in teleost larvae
DNA损伤检查点1（MDC1）的共调节活性与乳腺小叶癌中的DNA修复功能障碍及PARP抑制剂敏感性相关	Sottnik, J. L.	PDF	N/A	Co-regulator activity of Mediator of DNA Damage Checkpoint 1 (MDC1) is associated with DNA repair dysfunction and PARP inhibitor sensitivity in lobular carcinoma of the breast
使用正未标注机器学习识别人类mRNA 5'UTR序列中的潜在核开关元件	Raymond, W.	PDF	N/A	Identification of potential riboswitch elements in Homo Sapiens mRNA 5'UTR sequences using Positive-Unlabeled Machine learning
脂肪酸代谢和氧化应激反应支持细菌捕食	Jain, R.	PDF	N/A	Fatty Acid Metabolism and The Oxidative Stress Response Support Bacterial Predation
LysM-RLK在植物中发挥着古老的共生功能	Teyssier, E.	PDF	N/A	LysM-RLK plays an ancestral symbiotic function in plants
重组Physcomitrella FtsZ蛋白在体外依赖GTP的差异聚合作用	Milferstaedt, S. W. L.	PDF	N/A	Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins
POMC神经元通过在Kisspeptin神经元中对MC4R的不同信号传导来控制生育能力。	Talbi, R.	PDF	N/A	POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons
一个反馈驱动的脑类器官平台能够实现自动维护和高分辨率神经活动监测	Voitiuk, K.	PDF	N/A	A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring
40S核糖体蛋白RPS26和RPS25的不足，在脆性X相关条件下，对含聚甘氨酸蛋白的生物合成产生负面影响。	Tutak, K.	PDF	N/A	Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions
Wnt通路调控的细胞外基质蛋白聚糖的表达在东非慈鲷脂肪组织肥大的平行进化中起着重要作用。	Machii, N.	PDF	N/A	Pronounced expression of extracellular matrix proteoglycans regulated by Wnt pathway underlies the parallel evolution of lip hypertrophy in East African cichlids
成像流式细胞术能够实现从不可培养的细菌群体中对形态变异细胞的无标记分选。	Vocelle, D.	PDF	N/A	Imaging flow cytometry enables label-free cell sorting of morphological variants from unculturable bacterial populations.
新型酿酒酵母群落生态发酵研究模型设计	Pourcelot, E.	PDF	N/A	Design of a new model yeast consortium for ecological studies of enological fermentation
使用信息先验来解决存在鉴定错误的占据模型中的可识别性问题	Monchy, C.	PDF	N/A	Using informative priors to account for identifiability issues in occupancy models with identification errors
在预测编码模型中平衡先验知识和感官数据：对精神分裂症中连贯运动检测的洞察	Nemati, E.	PDF	N/A	Balancing Prior Knowledge and Sensory Data in a Predictive Coding Model: Insights into Coherent Motion Detection in Schizophrenia
动态调节小鼠海马体中由学习与记忆介导的NAT10介导的突触mRNA乙酰化	Zhou, H.-Q.	PDF	N/A	Dynamic regulation of NAT10-mediated mRNA acetylation at synapses by learning and memory in mouse hippocampus
PathoGFAIR：一套符合FAIR原则且可适应的（元）基因组工作流程，用于（食源性）病原体的检测和追踪	Nasr, E.	PDF	N/A	PathoGFAIR: a collection of FAIR and adaptable (meta)genomics workflows for (foodborne) pathogens detection and tracking
神经网络中模块性的出现与维持：基于Hebbian和反Hebbian抑制性STDP	Bergoin, R.	PDF	N/A	Emergence and maintenance of modularity in neural networks with Hebbian and anti-Hebbian inhibitory STDP
大规模并行遗传扰动揭示了淀粉样β核化反应的能量结构	Arutyunyan, A.	PDF	N/A	Massively parallel genetic perturbation reveals the energetic architecture of an amyloid beta nucleation reaction
C-C趋化因子受体4缺乏加剧了小鼠早期动脉粥样硬化	Tanaka, T.	PDF	N/A	C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice
预测无关信息：分心物可预测性的神经效应取决于任务负荷	Lui, T. K.-Y.	PDF	N/A	Predicting the irrelevant: Neural effects of distractor predictability depend on load
面部表情和言语运动中的时空结构与子状态	Cuve, H. C. J.	PDF	N/A	Spatiotemporal structure and substates in facial expressions and speech movements
关于蛋白质遗传结构分析：对“蛋白质序列景观并非如此简单”的回应	Park, Y.	PDF	N/A	On the Analysis of Protein Genetic Architecture: Response to "Protein sequence landscapes are not so simple"
解码HIV诱导的CPSF6斑点的生物发生及其与核斑点的融合	Tomasini, C.	PDF	N/A	Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle
用于神经场体内双光子荧光显微镜的自适应光学校正	Kang, I.	PDF	N/A	Adaptive optical correction for in vivo two-photon fluorescence microscopy with neural fields
认知网络通过通信子空间在大规模新皮层模型中的交互作用	Pereira-Obilinovic, U.	PDF	N/A	Cognitive networks interactions through communication subspaces in large-scale models of the neocortex
一个具有广泛宿主范围的锈菌中，假定效应因子的基因组内变异驱动了早期感染阶段	Degnan, R.	PDF	N/A	Intragenomic variants of a putative effector drive early-stage infection in a broad host-range rust fungus
利用新型病毒工具探索CA3记忆细胞性质的早期变化	Cupolillo, D.	PDF	N/A	Early changes in the properties of CA3 engram cells explored with a novel viral tool
识别基孔肯雅病毒nsP2 ATPase抑制剂	Navarro, H.	PDF	N/A	Identification of Inhibitors of Chikungunya virus nsP2 ATPase
大规模信息先验用于更好地预测稀有树相关微生境的局部发生率	Cottais, P.	PDF	N/A	Large-scale informative priors to better predict the local occurrence rate of a rare tree-related microhabitat
语言网络揭示了由基于结构域的词语构成的蛋白质句子的语法约束	Shimpi, A. A.	PDF	N/A	Linguistic networks uncover grammatical constraints of protein sentences comprised of domain-based words
BEVA2.0：通过模块化组装扩展遗传工程应用的金门兼容载体系统	Geddes, B. A.	PDF	N/A	BEVA2.0: Modular Assembly of Golden Gate-Compatible Vectors with Expanded Utility for Genetic Engineering
CGC1，一种新的秀丽隐杆线虫参考基因组	Ichikawa, K.	PDF	N/A	CGC1, a new reference genome for Caenorhabditis elegans
评估基因表达综合数据库（GEO）数据集中的偏差	Gondal, M. N.	PDF	N/A	Assessing Bias in Gene Expression Omnibus (GEO) Datasets
在蛋白质结构标记器中平衡局部性与重构性	Zhang, J.	PDF	N/A	Balancing Locality and Reconstruction in Protein Structure Tokenizer
哺乳至断奶过渡期间肠道上皮转录组变化的单细胞图谱	Malonga, T.	PDF	N/A	A single-cell atlas of transcriptome changes in the intestinal epithelium at the suckling-to-weaning transition
颌口类（Gnathostomata）胃的进化：通过基因组损失的研究发现——无胃物种的启示	Dann, J. B.	PDF	N/A	Evolution of the Jawed Vertebrate (Gnathostomata) Stomach through Gene Repertoire Loss: Findings from Agastric Species
MOZ和HBO1组蛋白乙酰转移酶复合物是NUP98重排急性髓系白血病的分子依赖性和治疗靶点	Michmerhuizen, N. L.	PDF	N/A	MOZ and HBO1 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia
果蝇大脑中已鉴定神经元的突触图谱分析	Wu, H.	PDF	N/A	Synapse profiling of identified neurons in the Drosophila brain
章鱼胺信号协调果蝇蘑菇体中突触前机制的空间模式	Wu, H.	PDF	N/A	Octopamine signals coordinate the spatial pattern of presynaptic machineries in the Drosophila mushroom bodies
高通量定量miRNA-3'-非翻译区调控效应	Mastriano, S.	PDF	N/A	High-Throughput Quantification of miRNA-3'-Untranslated-Region Regulatory Effects
在秀丽隐杆线虫中对Rab GTPase基因进行RNAi筛选发现，生殖系统的体细胞在形态发生过程中依赖于rab-1，但在干细胞龛位的维持中并不依赖于rab-1。	Scott, K. F.	PDF	N/A	An RNAi screen of Rab GTPase genes in C. elegans reveals that somatic cells of the reproductive system depend on rab-1 for morphogenesis but not stem cell niche maintenance
不同的分化轨迹对V2a中间神经元的基因调控和功能产生持久影响。	Elder, N. H.	PDF	N/A	Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a interneurons
立克次氏菌细菌的比较基因组学揭示了与节肢动物共生相互作用中涉及的可变代谢特征	Floriano, A. M. M.	PDF	N/A	Comparative genomics of Rickettsiella bacteria reveal variable metabolic traits involved in symbiotic interactions with arthropods
利用从头设计的蛋白质抑制致病性大肠杆菌的血红素盗取	Fox, D. R.	PDF	N/A	Inhibiting heme-piracy by pathogenic Escherichia coli using de novo-designed proteins
CRISPR-Cas13高效抑制剂的从头设计	Taveneau, C.	PDF	N/A	De novo design of potent CRISPR-Cas13 inhibitors
基于亮氨酸拉链的SAIM成像技术可识别用于破坏癌细胞糖萼以增强免疫治疗的药物	Park, S.	PDF	N/A	Leucine zipper-based SAIM imaging identifies therapeutic agents to disrupt the cancer cell glycocalyx for enhanced immunotherapy
水溶性CD20抗原的设计与计算表位支架构建	Yao, Z.	PDF	N/A	Design of a Water-Soluble CD20 Antigen with Computational Epitope Scaffolding
IP6阴离子结合对HIV-1衣壳组装分子开关的动态影响	Gupta, M.	PDF	N/A	Kinetic Implications of IP6 Anion Binding on the Molecular Switch of the HIV-1 Capsid Assembly
结核分枝杆菌CrgA形成二聚体结构，其跨膜结构域夹在胞质和周质β片层之间，从而能够与多个分裂体蛋白进行多重相互作用。	Shin, Y.	PDF	N/A	Mycobacterium tuberculosis CrgA Forms a Dimeric Structure with Its Transmembrane Domain Sandwiched between Cytoplasmic and Periplasmic β-Sheets, Enabling Multiple Interactions with Other Divisome Proteins
PIP2激活和SEA0400抑制在人类心脏钠钙交换体NCX1中的结构机制	Xue, J.	PDF	N/A	Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1
多尺度建模展示了细胞-细胞外基质相互作用如何影响细胞外基质纤维排列和细胞脱离	Arellano-Tinto, J.	PDF	N/A	Multiscale modelling shows how cell-ECM interactions impact ECM fibre alignment and cell detachment
小热休克蛋白客户隔离与诱导多分散性的机制	Miller, A. P.	PDF	N/A	Mechanism of small heat shock protein client sequestration and induced polydispersity
基于微阀的免流梯度发生器	Bohec, P.	PDF	N/A	Microvalve-based devices for flow-free gradient generators
明确分配弯曲的β片层有助于深入理解生物分子凝聚物中可逆性的分子语法	Roy, I.	PDF	N/A	Unambiguous assignment of kinked beta sheets leads to insights into molecular grammar of reversibility in biomolecular condensates
登革病毒非结构5（NS5）与启动子茎环A（SLA）相互作用的结构动力学	Obi, J. O.	PDF	N/A	Structural Dynamics of the Dengue Virus Non-structural 5 (NS5) Interactions with Promoter Stem Loop A (SLA)
CIGB-300在肺鳞状细胞癌蛋白质组学中的时间依赖性和剂量依赖性效应。	Garcia, L. E.	PDF	N/A	Time- and Dose-dependent Effects of CIGB-300 in the lung squamous cell carcinoma proteomics.
膜相关泛素连接酶MARCHF8通过降解MHC I类蛋白促进癌症免疫逃逸	Khalil, M. I.	PDF	N/A	The membrane-associated ubiquitin ligase MARCHF8 promotes cancer immune evasion by degrading MHC class I proteins
人类mGlu5变构调节剂的药理学特征	Razzak, M.	PDF	N/A	Pharmacological characterisation of allosteric modulators at human mGlu5
来自乌克兰东部不同R-E半克隆种群系统的Pelophylax水蛙的杂交生殖：选择性死亡率、克隆和倍性多样性	Fedorova, A.	PDF	N/A	Hybridogenetic reproduction of Pelophylax water frogs from different R-E hemiclonal population systems from Eastern Ukraine: selective mortality, clonal and ploidy diversity
在腰果占主导地位的生物多样性热点地区，种植园内及周边森林覆盖的本地树木对鸟类保护至关重要。	Madhu, N.	PDF	N/A	Native trees within plantations and surrounding forest cover are essential for bird conservation in cashew-dominated landscapes within a biodiversity hotspot
伊维菌素在秀丽隐杆线虫（Caenorhabditis elegans）这一线虫模型中的抗性进化：种群大小的重要影响及对依莫德吡的意外交叉抗性	Hellinga, J.	PDF	N/A	Evolution of ivermectin resistance in the nematode model Caenorhabditis elegans: critical influence of population size and unexpected cross-resistance to emodepside
尿道双J导管复杂微生物群落的表型特征及细菌相互作用	Farizano, J. V.	PDF	N/A	PHENOTYPIC CHARACTERIZATION AND BACTERIAL INTERACTIONS OF THE COMPLEX MICROBIAL POPULATION IN URINARY DOUBLE-J CATHETERS
铜绿假单胞菌（Pseudomonas aeruginosa）对血清素、多巴胺、肾上腺素和去甲肾上腺素表现出趋化性。	Monteagudo-Cascales, E.	PDF	N/A	Pseudomonas aeruginosa performs chemotaxis to serotonin, dopamine, epinephrine, and norepinephrine
特定阶段的预运动抑制调节了水蛭的节律性运动输出	Radice, M.	PDF	N/A	Phase-specific premotor inhibition modulates leech rhythmic motor output
糖蛋白pherophorin II的时空分布揭示了Volvox carteri生长中的细胞外基质的随机几何结构	von der Heyde, B.	PDF	N/A	Spatiotemporal distribution of the glycoprotein pherophorin II reveals stochastic geometry of the growing ECM of Volvox carteri
模拟为贝特曼梯度提供了机制性解释。	Sanghvi, K.	PDF	N/A	Simulations provide a mechanistic interpretation of Bateman gradients
从色素到精准：探索小麦和大麦的基因转化与基因组编辑	Prusty, M. R.	PDF	N/A	From Pigments to Precision: Exploring Genetic Transformation and Genome Editing in Wheat and Barley
R-环语法预测了在不同拓扑约束下R-环的形成。	Ferrari, M. M.	PDF	N/A	The R-loop Grammar predicts R-loop formation under different topological constraints
在成年期，目标导向导航的认知和运动能力下降是可分离的，并贯穿整个生命周期。	LAncia, G. L.	PDF	N/A	Separable cognitive and motor decline tracked across adult life-span for goal-directed navigation
利用下一代测序数据的生物信息学分析，鉴定与阿尔茨海默病相关的候选生物标志物和信号通路	Vastrad, B. M.	PDF	N/A	Identification of candidate biomarkers and signaling pathways associated with Alzheimer's disease using bioinformatics analysis of next generation sequencing data
用于从单细胞转录组数据预测样本表型的可解释深度神经网络	Martorell-Marugan, J.	PDF	N/A	Explainable deep neural networks for predicting sample phenotypes from single-cell transcriptomics
GJB3是一种缝隙连接基因，通过介导胱氨酸摄取和调节细胞应激途径，支持SLC7A11低表达的腺癌中的细胞生长。	Acharya, D.	PDF	N/A	GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomas
DeepGraphMut：一种基于图的深度学习方法，利用体细胞突变谱进行癌症预后分析	Jose, A.	PDF	N/A	DeepGraphMut: A graph-based deep learning methodfor cancer prognosis using somatic mutation profile
2024年荷兰蓝舌病毒12型 - 首次在欧洲报告的蓝舌病毒血清型	van den Brom, R.	PDF	N/A	Bluetongue virus serotype 12 in the Netherlands in 2024 - A BTV serotype reported in Europe for the first time
自愿行为能增强感官预测能力，并促进对相关感官刺激的神经处理。	Ody, E.	PDF	N/A	Voluntary action sharpens sensory prediction and facilitates neural processing of contingent sensory stimuli
在自身免疫性脱髓鞘模型中揭示的变节抗体：从生物学到治疗	Taghipour-Mirakmahaleh, R.	PDF	N/A	Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy
乳酸乳球菌亚种乳脂亚种C60通过功能性修饰树突状细胞，创造了一种以I型调节性T细胞为主导的抗炎肠道环境。	Saito, S.	PDF	N/A	Lactococcus lactis subsp. cremoris C60 creates a type I regulatory T cell-dominant anti-inflammatory intestinal environment through functional modification of dendritic cells
三种Candidatus Liberibacter solanacearum载体（Dyspersa apicalis、Dyspersa pallida和Trioza urticae）的染色体水平组装（半翅目：瘿蚊科）	Heaven, T.	PDF	N/A	Chromosome-level Assemblies of Three Candidatus Liberibacter solanacearum Vectors: Dyspersa apicalis, Dyspersa pallida, and Trioza urticae (Hemiptera: Psylloidea)
通过长读长测序进行血红蛋白病变异的综合检测	Xiang, J.	PDF	N/A	The comprehensive detection of hemoglobinopathy variants via long-read sequencing
人类肠道微生物群中两个关键的放线菌门分类群与曼氏血吸虫感染负担相关	Appiah-Twum, F.	PDF	N/A	Two Key Actinomycetota Taxa in the Human Gut Microbiota are Associated with Schistosoma mansoni Infection Burden
电影间的差异性严重限制了“自然主义”神经影像学研究结果的可推广性。	Leipold, S.	PDF	N/A	Between-movie variability severely limits generalizability of "naturalistic" neuroimaging
Dnmt3a介导的新生甲基化平衡了Th1和Tfh记忆细胞的可塑性和功能性。	Perkins, B.	PDF	N/A	Dnmt3a-mediated de novo methylation balances Th1 and Tfh memory cell plasticity and functionality
Tokenvizz：基于GraphRAG的基因组数据发现与可视化标记化工具	Oguztuzun, C.	PDF	N/A	Tokenvizz: GraphRAG-Inspired Tokenization Tool for Genomic Data Discovery and Visualization
同时抑制MDM2和PARP在p53野生型横纹肌肉瘤模型中产生协同抗肿瘤效应	Pons, G.	PDF	N/A	Combined inhibition of MDM2 and PARP lead to a synergistic anti-tumoral response in p53 wild-type rhabdomyosarcoma models
运动可以缓解肝脏衰老，但在饮食诱导的MASLD中，其效果并不优于饮食限制。	Katsarou, A.	PDF	N/A	Exercise alleviates liver senescence but does not outmatch the effect of dietary restriction in diet-induced MASLD
一种用于急性视网膜外植体中光感受器和神经节细胞联合功能评估的方法	He, X.	PDF	N/A	A Method for the Combined Functional Assessment of Photoreceptors and Ganglion Cells in Acute Retinal Explants
紧张性冷痛的神经动力学：对健康个体在扫描仪内冷压测试替代方法的新研究	Medina, S.	PDF	N/A	Neural Dynamics of Tonic Cold Pain: A Novel Investigation of an In-Scanner Alternative to the Cold Pressor Test in Healthy Individuals
空间注意力和特征选择性注意力相互作用，驱动前顶叶皮层的选择性编码	Dermody, N.	PDF	N/A	Spatial and feature-selective attention interact to drive selective coding in frontoparietal cortex
使用CellREADR在人脑皮层中进行RNA可编程的细胞类型监测与操控	Matthews, E. A.	PDF	N/A	RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR
捕获SARS-CoV-2刺突蛋白融合中间构象需要受体结合以及在S1/S2或S2'位点的切割	Lusvarghi, S.	PDF	N/A	Capture of fusion-intermediate conformations of SARS-CoV-2 spike requires receptor binding and cleavage at either the S1/S2 or S2' site
SARS-CoV-2对高尔基体结合的PI4P的捕食，引发了细胞质中DNA损伤反应激酶ATM的大规模激活。	Rebendenne, A.	PDF	N/A	SARS-CoV-2 predation of Golgi-bound PI4P primes the massive activation of the DNA Damage Response kinase ATM in the cytoplasm
高效地利用CUT&RUN技术进行染色质相关靶点的基因组定位	Firestone, T. M.	PDF	N/A	High-efficiency genomic mapping of chromatin-associated targets with CUT&RUN
滞留短新生链测序揭示了布氏锥虫中真核DNA复制起源的拓扑结构。	STANOJCIC, S.	PDF	N/A	Stranded short nascent strand sequencing reveals the topology of eukaryotic DNA replication origins in Trypanosoma brucei.
发育程序推动细胞可塑性、疾病进展和肺腺癌中的治疗抵抗	Bienkowska, K. J.	PDF	N/A	Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma
白血病细胞内在和外在因素相互协作，促进了KMT2A重排的B-ALL在中枢神经系统（CNS）微环境中的生存和增殖。	Duguid, A.	PDF	N/A	Leukaemia cell intrinsic and extrinsic factors cooperate to facilitate the survival and proliferation of KMT2A-rearranged B-ALL in the CNS niche.
IGFs调控前列腺癌中的癌细胞免疫逃逸	Nandakumar, A. M.	PDF	N/A	IGFs regulate cancer cell immune evasion in prostate cancer
转用电子烟可恢复吸烟小鼠对屋尘螨的免疫反应。	Warren, K. J.	PDF	N/A	Transitioning to e-cigarettes restores the immune response to house dust mite in cigarette smoked mice.
一个用于探索海草生态系统中细菌-病毒动力学的基因组资源	Ettinger, C. L.	PDF	N/A	A genomic resource for exploring bacterial-viral dynamics in seagrass ecosystems
化学基因组学揭示了鲍曼不动杆菌中抗生素和必需基因的功能	Tran, J. S.	PDF	N/A	Chemical genomics informs antibiotic and essential gene function in Acinetobacter baumannii
宏基因组挖掘揭示了双链DNA病毒中的新型病毒组蛋白	Liu, Y.	PDF	N/A	Metagenomic mining reveals novel viral histones in dsDNA viruses
使用声波液体处理器的两步扩增子PCR效率提升	Benz, B. R.	PDF	N/A	Improved Efficiency of Two-Step Amplicon PCR Using an Acoustic Liquid Handler
体内检测未接受治疗和接受抗逆转录病毒治疗（ART）的HIV-1反义转录本	Capoferri, A. A.	PDF	N/A	In vivo detection of HIV-1 antisense transcripts in untreated and ART-treated individuals
EV-D68感染期间诱导的线粒体自噬体促进病毒的非裂解性释放	Jassey, A.	PDF	N/A	Mitophagosomes induced during EV-D68 infection promote viral nonlytic release
滴灌通过重塑水稻根际微生物群落来抑制甲烷排放。	Lau, K. J. X.	PDF	N/A	Drip irrigation suppresses methane emissions by reshaping the rhizosphere microbiomes in rice
利用放线菌的生物合成多样性：通过比较基因组和代谢分析发现独特的天然产物	Kikuchi, Y.	PDF	N/A	Harnessing the Biosynthetic Diversity of Actinomycetes: Discovery of Unique Natural Products through Comparative Genomic and Metabolic Analysis
通过综合蛋白质组学方法探索病毒与宿主相互作用，发现BANF1是非洲猪瘟病毒的新关键因子。	Dupre, J.	PDF	N/A	Exploring virus-host interactions through combined proteomic approaches identifies BANF1 as a new essential factor for African Swine Fever Virus.
LEDGF/p75介导的整合中断会解除对HIV-1基因组反义转录的抑制	Tedbury, P. R.	PDF	N/A	Disruption of LEDGF/p75-directed integration derepresses antisensetranscription of the HIV-1 genome
泛素样蛋白（UBLs）的蛋白质和小分子底物的全局分析	Shao, G.	PDF	N/A	Global analysis of protein and small-molecule substrates of ubiquitin-like proteins (UBLs)
利用工程细胞分裂素调节剂可预测地调控植物根系发育	Rattan, R.	PDF	N/A	Predictable modulation of plant root development using engineered cytokinin regulators
用于工程合成基因组模块和染色体的迭代SCRaMbLE	Lu, X.	PDF	N/A	Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes
Vgamma1+ γδ T细胞衍生的IL-4启动CD8 T细胞免疫	Le, S.	PDF	N/A	Vgamma1+ gammadelta T cell-derived IL-4 initiates CD8 T cell immunity
来得容易，去得更快：绘制整个生命树中鞭毛运动能力的丧失图谱	Philip, J. S.	PDF	N/A	Easy come, easier go: mapping the loss of flagellar motility across the tree of life
培养及分子表征孕妇分娩前留置导尿管尿液、清洁中段尿及阴道拭子	Greenberg, J. M.	PDF	N/A	Cultivation and molecular characterization of Foley catheterized urine, clean catch urine, and vaginal swabs from pregnant women prior to delivery
原生动物种群驱动瘤胃微生物组的系统性变异	Kobel, C. M.	PDF	N/A	Protozoal populations drive system-wide variation in the rumen microbiome
肝素酶，一种强效抑制逆转录病毒转录的宿主基因	Waxman, B.	PDF	N/A	Heparanase, a host gene that potently restricts retrovirus transcription
人类中siRNAs介导的基因沉默的结构基础	Sarkar, S.	PDF	N/A	Structural basis for gene silencing by siRNAs in humans
Chd1的CHCT结构域与Rtf1之间的直接相互作用控制着Chd1在活性基因上的分布以及核小体的定位。	Tripplehorn, S. A.	PDF	N/A	A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes
RNA介导的MYC多聚化抑制先天免疫信号传导	Uhl, L.	PDF	N/A	RNA-mediated MYC multimerization suppresses innate immune signaling
资源防御在促进性选择武器进化中的作用：一项实验进化测试	Audet, T.	PDF	N/A	The role of resource defensibility in facilitating sexually-selected weapon evolution: An experimental evolution test
印度不同地理区域埃及伊蚊种群中电压门控钠通道（VGSC）基因IIS6结构域的遗传多样性	Sumitha, M. K.	PDF	N/A	Genetic diversity in the IIS6 domain of Voltage Gated Sodium Channel (VGSC) gene among Aedes aegypti populations from different geographical regions in India
人类肠道微生物组中氨基酸脱羧酶酶的多样性与普遍性——一项生物信息学研究	Sandoval, M.	PDF	N/A	Diversity and prevalence of amino acid decarboxylase enzymes in the human gut microbiome -- a bioinformatics investigation
对库蠓属蚊虫（Culicoides sonorensis）进行的实验性BTV-3和BTV-8病毒感染	Zeiske, S.	PDF	N/A	Experimental BTV-3 and BTV-8 infection of Culicoides sonorensis biting midges
酵母中依赖RNA的蛋白质的普查	Waber, N. B.	PDF	N/A	A census of RNA-dependent proteins in yeast
评估用于归巢抑制基因驱动的目标基因	Xu, X.	PDF	N/A	Assessing target genes for homing suppression gene drive
研究同多聚体儿茶酚1,2-双加氧酶的四级结构：一项综合结构生物学研究。	Almeida-Juarez, A. G.	PDF	N/A	Investigating the quaternary structure of a homomultimeric catechol 1,2-dioxygenase: An integrative structural biology study.
通用节奏架构揭示了不同的神经动力学模式	K, G.	PDF	N/A	Universal rhythmic architecture uncovers distinct modes of neural dynamics
振荡爆发特征与人类工作记忆期间偏差之间的关联	Kavanaugh, B.	PDF	N/A	The association between oscillatory burst features and deviations during human working memory
意志调节与中脑振荡的可转移模式	Lu, H.-Y.	PDF	N/A	Volitional Regulation and Transferable Patterns of Midbrain Oscillations
人类海马体在导航和心理模拟过程中低频振荡的异同	Seger, S.	PDF	N/A	Differences and similarities between human hippocampal low-frequency oscillations during navigation and mental simulation
成年视觉剥夺会引发与丘脑皮质输入相关的突触前可塑性	Murase, S.	PDF	N/A	Adult visual deprivation engages associative, presynaptic plasticity of thalamic input to cortex
在使用Cntnap2基因敲除的自闭症大鼠模型进行语音辨别任务时，使用预测提示	Centanni, T. M.	PDF	N/A	Use of a predictor cue during a speech sound discrimination task in a Cntnap2 knockout rat model of autism
诚然夸张：吼猴的咆哮声是体型大小的可靠信号，并且对听者具有行为上的相关性。	Dunn, J. C.	PDF	N/A	Honestly exaggerated: howler monkey roars are reliable signals of body size and behaviourally relevant to listeners
早产儿出生后，大脑发育呈现出异质性、时间一致性和可塑性。	Thalhammer, M.	PDF	N/A	Heterogeneous, temporally consistent, and plastic brain development after preterm birth
观察言语：先天性聋和听力正常者在提示性言语感知中的神经机制	Sarre, A.	PDF	N/A	Seeing speech: neural mechanisms of cued speech perception in prelingually deaf and hearing users
在认知控制下，大脑会根据需要选择性地将能量分配给功能性脑网络。	Saberi, M.	PDF	N/A	The brain selectively allocates energy to functional brain networks under cognitive control
# BioRxiv 2024-12-05 Papers

标题	作者	PDF链接	代码仓库	Title
模拟西欧的欧亚猞猁种群：未来50年的前景如何？	Bauduin, s.	PDF	N/A	Modelling Eurasian lynx populations in Western Europe: What prospects for the next 50 years?
利用Fisher核方法从脑动力学模型中准确可靠地预测个体特征	Ahrends, C.	PDF	N/A	Predicting individual traits from models of brain dynamics accurately and reliably using the Fisher kernel
Heron：一个直观的知识图谱编辑器，用于实现基于Python的实验流程。	Dimitriadis, G.	PDF	N/A	Heron: A Knowledge Graph editor for intuitive implementation of python based experimental pipelines.
作为肺结核的辅助治疗药物——去铁胺	Kaushik, S. R.	PDF	N/A	Deferoxamine as adjunct therapeutics for tuberculosis
产生相同M矩阵的替代突变架构可能导致不同的进化分歧模式	Jiang, D.	PDF	N/A	Alternative mutational architectures producing identical M-matrices can lead to different patterns of evolutionary divergence
异质性突触稳态：一种提升皮层信息传播的新机制	Razi, F.	PDF	N/A	Heterogeneous Synaptic Homeostasis: A Novel Mechanism Boosting Information Propagation in the Cortex
转座子活性在全基因组复制后塑造顺式调控元件进化中的作用	Monsen, O.	PDF	N/A	The role of transposon activity in shaping cis-regulatory element evolution after whole genome duplication
皮质纹状体动作控制固有的对立认知动机风格	Avila, C.	PDF	N/A	Cortico-striatal action control inherent of opponent cognitive-motivational styles
有效连接预测知觉决策信心、不确定性和速度的分布式神经编码	Asadpour, A.	PDF	N/A	Effective connectivity predicts distributed neural coding of perceptual decision confidence, uncertainty and speed
球形表型聚类	Nightingale, L.	PDF	N/A	Spherical Phenotype Clustering
多组织网络分析揭示JNK抑制对饮食蔗糖引起的大鼠代谢功能障碍的影响	Mardinoglu, A.	PDF	N/A	Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
病毒适应与致死性突变的瞬时进化流行病学	Guillemet, M.	PDF	N/A	Transient evolutionary epidemiology of viral adaptation and lethal mutagenesis
深层组织空间组学：以高空间分辨率成像整个胚胎的转录组和亚细胞结构	Gandin, V.	PDF	N/A	Deep-tissue spatial omics: imaging whole-embryo transcriptomics and subcellular structures at high spatial resolution
Rtc调控的RNA修复机制模型提示了增强抗生素效果的分子靶点。	Hindley, H. J.	PDF	N/A	A mechanistic model of Rtc-regulated RNA repair suggests molecular targets to potentiate antibiotic effects
整合代谢建模与成像技术用于筛选结直肠癌治疗靶点	Tavakoli, N.	PDF	N/A	Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer
2022年初印度突破性感染血清针对保守的隐秘5类表位，以对抗SARS-CoV-2变种的免疫逃逸。	Das Jana, I.	PDF	N/A	Early 2022 breakthrough infection sera from India target the conserved cryptic class 5 epitope to counteract immune escape by SARS-CoV-2 variants
通过深度突变扫描技术，解析MET受体酪氨酸激酶激酶结构域的耐药机制	Estevam, G. O.	PDF	N/A	Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
功能基因嵌入提高了罕见变异的复杂遗传风险评分	Londhe, S.	PDF	N/A	Functional gene embeddings improve rare variant polygenic risk scores
细胞分化过程中基因表达的内在维度	Biondo, M.	PDF	N/A	The intrinsic dimension of gene expression during cell differentiation
在猪链球菌发病机制中荚膜多糖的调节合成	Wang, X.	PDF	N/A	Regulative synthesis of capsular polysaccharides in the pathogenesis of Streptococcus suis
钙从内质网向其他细胞器的转移在弓形虫中对最佳信号传导至关重要。	Li, Z.-H.	PDF	N/A	Calcium transfer from the ER to other organelles for optimal signaling in Toxoplasma gondii.
在帕金森病中，运动方向快速逆转期间，丘脑底核-皮层同步性的情境依赖性调制	Winkler, L.	PDF	N/A	Context-Dependent Modulations of Subthalamo-Cortical Synchronization during Rapid Reversals of Movement Direction in Parkinson's Disease
胸侧半切术后控制系带行走和分带行走时相持续时间的脊髓感觉运动回路的运作	Rybak, I. A.	PDF	N/A	Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection
巴巴利猕猴社交信息的化学特征	Weiss, B. M.	PDF	N/A	Chemical signatures of social information in Barbary macaques
农业集约化导致的遗传多样性丧失及有害突变暴露	Nolen, Z. J.	PDF	N/A	Species-specific loss of genetic diversity and exposure of deleterious mutations following agricultural intensification
多站点研究中基于扩散磁共振成像的结构连接组的协调	Shen, R. S.	PDF	N/A	Harmonization of Diffusion MRI-based Structural Connectomes for Multi-site Studies
DeepPaint：一个用于细胞显像图像分类的深度学习工具包	Luna, D.	PDF	N/A	DeepPaint: A deep-learning package for Cell Painting Image Classification
受体信号放大定量分析：全激动剂的Kd/EC50比值作为增益参数	Buchwald, P.	PDF	N/A	Quantification of Signal Amplification for Receptors: The Kd/EC50 Ratio of Full Agonists as a Gain Parameter
O-特异性抗原的丧失塑造了假单胞菌在小鼠临床前肺部感染模型中的微生物地理分布	Fraser, H.	PDF	N/A	Loss of O-specific antigen shapes Pseudomonas aeruginosa microbiogeography in murine preclinical pulmonary infection model
在空间导航过程中，对决策神经动力学的全脑表征	Haley, S. P.	PDF	N/A	Cortex-wide characterization of decision-making neural dynamics during spatial navigation
突破屏障：真菌毒素白念珠菌素在肠道芯片模型中破坏上皮完整性并诱发炎症	Morelli, M.	PDF	N/A	Breaking barriers: the fungal toxin candidalysin disrupts epithelial integrity and induces inflammation in a gut-on-chip model
禾本科姐妹种的基因组揭示了草类出现之前的关键代谢创新	Takeda-Kimura, Y.	PDF	N/A	Genomes of Poaceae sisters reveal key metabolic innovations preceding the emergence of grasses
4-甲基七叶皂苷（4-MU）可改善大鼠脑缺血/再灌注损伤后的学习和记忆能力。	Tamouk, S.	PDF	N/A	4-Methyllumifrone (4-MU) can improve learning and memory after cerebral ischemia/reperfusion injury in rats
耶氏解脂耶氏酵母中基因编码报告基因的总体评价	Zhang, H.	PDF	N/A	General assessment of genetically-encoded reporters in Yarrowia lipolytica
多核巨细胞是卵巢衰老的标志，具有独特的免疫和降解相关分子特征。	Converse, A.	PDF	N/A	Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures
HIV-1蛋白编码序列存在于相关细菌中	Pelaez-Prestel, H. F.	PDF	N/A	HIV-1 protein coding sequences are present in relevant bacteria
葡萄糖感应ChREBP蛋白在糖尿病视网膜病变发病机制中的作用	Starr, C. R.	PDF	N/A	Glucose-Sensing ChREBP Protein in the Pathogenesis of Diabetic Retinopathy
从一位患有年轻型糖尿病10型（由杂合INS突变引起）的患者中衍生出的诱导多能干细胞系ERCi003-A的生成	Bastrich, A.	PDF	N/A	Generation of an induced pluripotent stem cell line ERCi003-A derived from a patient with maturity-onset diabetes of the young type 10 caused by a heterozygous INS mutation
非经典Sun1-Allan复合体在快速有丝分裂期间调控核膜重塑和基体/微管组织中心分离	Zeeshan, M.	PDF	N/A	Non canonical Sun1-Allan complex orchestrates nuclear envelope remodelling and Basal Body/MTOC Segregation during rapid mitosis in Plasmodium
一种新型SUN1-ALLAN复合物在恶性疟原虫快速闭合有丝分裂期间协调核膜两侧的双极中心粒分离	Zeeshan, M.	PDF	N/A	A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium
胞外HDAC6 ZnF UBP结构域增强足体介导的神经元迁移	Qureshi, T.	PDF	N/A	Extracellular HDAC6 ZnF UBP domain enhances podosome-mediated neuronal migration
从一名年轻型糖尿病3型患者的皮肤成纤维细胞中生成了iPSC系ERCi004-A，该患者因HNF1A基因的杂合突变而患病。	Bastrich, A.	PDF	N/A	Generation of iPSC line ERCi004-A from human dermal fibroblasts of a patient with maturity-onset diabetes of the young type 3 caused by a heterozygous mutation in the HNF1A gene
自闭症蛋白质在纤毛处的汇聚	Kostyanovskaya, E.	PDF	N/A	Convergence of autism proteins at the cilium
自闭症蛋白在纤毛处的汇聚	Kostyanovskaya, E.	PDF	N/A	Convergence of autism proteins at the cilium
EOR-1/PLZF调控的WAH-1/AIF依次促进非凋亡性尸体清除的早期和晚期阶段	Rather, N.	PDF	N/A	EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removal
EOR-1/PLZF调控的WAH-1/AIF依次促进非凋亡性尸体清除的早期和晚期阶段	Rather, N.	PDF	N/A	EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removal
缺血后处理的心脏保护作用是通过抑制RAP2C-MAP4K4通路介导的	Zhang, M.	PDF	N/A	The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway
抑制巨核细胞中RhoA介导的分泌性自噬可减轻小鼠的骨髓纤维化	Becker, I. C.	PDF	N/A	Inhibition of RhoA-mediated secretory autophagy in megakaryocytes mitigates myelofibrosis in mice
热应激对卵巢、卵泡和卵母细胞的影响：系统综述	Zhou, L. T.	PDF	N/A	The Effects of Heat Stress on the Ovary, Follicles and Oocytes: A Systematic Review
CGC1，一种新的大肠杆菌参考基因组	Ichikawa, K.	PDF	N/A	CGC1, a new reference genome for Caenorhabditis elegans
生物分子凝聚物通过可移动的锚定物促进膜润湿	GrandPre, T.	PDF	N/A	Membrane wetting by biomolecular condensates is facilitated by mobile tethers
AER-270和TGN-020不是水通道蛋白-4水通道阻断剂。	Unger, L.	PDF	N/A	AER-270 and TGN-020 are not aquaporin-4 water channel blockers
肠道微生物群认知：我们对肠道微生物群了解多少？一项国际问卷调查。	Garcia-Gutierrez, E.	PDF	N/A	Gut MicrobiotAware: how much do we know about gut microbiota? An international questionnaire.
隐孢子虫胞内生存所需的主机基因揭示了可用于治疗的代谢依赖性	Marzook, N. B.	PDF	N/A	The essential host genome for Cryptosporidium intracellular survival exposes metabolic dependencies that can be leveraged for treatment
索莫莫浅井水中沙门氏菌的表征及其对肯尼亚埃尔多雷特莫里加·奥列费拉种子提取物的抗菌敏感性	Cheronoh, J.	PDF	N/A	Characterization of Salmonella typhi from Shallow Well Water in Sogomo, Eldoret- Kenya and its Antimicrobial Sensitivity to Moringa oleifera Seed Extract
CHD4与TBX5相互作用，以维持出生后心房肌细胞的基因调控网络	Sweat, M. E.	PDF	N/A	CHD4 Interacts With TBX5 to Maintain the Gene Regulatory Network of Postnatal Atrial Cardiomyocytes
利用联合物种分布模型检测群落中的生态进化动力学	Pantel, J. H.	PDF	N/A	Detection of eco-evolutionary dynamics in communities using Joint Species Distribution Models
芸苔属植物和其传粉者之间的相互作用受到蜜蜂群落管理和新烟碱类种子处理的影响。	Nottebrock, H.	PDF	N/A	Interactions between Brassica carinata and its pollinators is shaped by managed beehives and neonicotinoid seed treatment
低投入土壤管理在提高产量和减少二氧化碳排放的同时，却加剧了气候变化下冬小麦种植系统中硝酸盐淋失和病害的风险。	Michel, J.	PDF	N/A	Low-input soil management increases yield and decreases CO2-emissions but aggravates risk of nitrate leaching and diseases in winter wheat cropping systems under climate change
大陆边缘沉积物中甲烷循环古菌丰度、群落结构及分解代谢途径的驱动因素	Deng, L.	PDF	N/A	Drivers of methane-cycling archaeal abundances, community structure, and catabolic pathways in continental margin sediments
小RNA调控与基因组和谐：对沼泽兰花（Dactylorhiza）异源多倍体进化的见解	Eriksson, M. C.	PDF	N/A	Small RNAs regulation and genomic harmony: insights into allopolyploid evolution in marsh orchids (Dactylorhiza)
年龄和性激素对女性在整个成年期神经肌肉功能的影响	O'Bryan, S. J.	PDF	N/A	The effect of age and sex hormones on female neuromuscular function across the adult lifespan
增强CAR-T细胞的狂犬病毒受限于I型干扰素和快速收缩	Burchett, R.	PDF	N/A	Boosting of CAR-T cells with rhabdovirus is limited by type I interferon and rapid contraction
贝叶斯最小二乘超树（BLeSS）：灵活推断大型时间校准系统发育树	Cerny, D.	PDF	N/A	Bayesian Least-Squares Supertrees (BLeSS): flexible inference of large time-calibrated phylogenies
基于有限元分析的股骨颈骨折固定生物力学评估	Rao, L.	PDF	N/A	Biomechanical Evaluation of Femoral Neck Fracture Fixation Based on Finite Element Analysis
通过DECIPHER实现大规模异质空间组学的高保真解耦细胞嵌入	Xia, C.-R.	PDF	N/A	High-fidelity disentangled cellular embeddings for large-scale heterogeneous spatial omics via DECIPHER
评估基于性别和种族的基因表达综合数据库（GEO）数据集中的多样性、公平性和包容性（DEI）偏见	Gondal, M. N.	PDF	N/A	Assessing DEI Bias in Gene Expression Omnibus (GEO) Datasets Based on Gender and Ethnicity
脑肿瘤和黑色素瘤来源的细胞系对替莫唑胺的敏感性：与MGMT基因表达的关系	Baguley, B. C.	PDF	N/A	Sensitivity to temozolomide of cell lines derived from brain tumours and melanomas: relationship to MGMT gene expression
巨胞饮作用调控代谢应激驱动的胰腺癌中癌症相关成纤维细胞亚型身份	Zhang, Y.	PDF	N/A	Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer
性别特异性见解：药物诱导的小鼠寿命延长与体重减轻	Belikov, A. V.	PDF	N/A	Sex-specific insights into drug-induced lifespan extension and weight loss in mice
酒精会下调原肠胚基因表达和细胞运动，导致胎儿酒精谱系障碍的症状。	Alsakran, A. A.	PDF	N/A	Ethanol down-regulates gastrula gene expression and cell movement, causing symptoms of foetal alcohol spectrum disorders
建模决策和反馈控制在变化环境中对生物体的利弊	Kumar, R.	PDF	N/A	Modelling benefits and costs of decision making and feedback control for organisms in changing environments
系统生物学的通用微分方程：当前状态与开放问题	Philipps, M.	PDF	N/A	Universal differential equations for systems biology: Current state and open problems
患者来源的PBMCs的体外扩增优先导致效应记忆T细胞的增殖，并恢复了HBV-HCC中的自体效率。	Kah, J.	PDF	N/A	Ex-vivo expansion of patient-derived PBMCs preferentially results in effector memory T-cell proliferation with restored autologous efficiency in HBV-HCC
海洋青鳉对二噁英的反应与其近亲淡水青鳉（日本青鳉）有所不同：其AHR分子机制存在差异。	Zhang, W.	PDF	N/A	Marine medaka responds differently to dioxin compared with its close freshwater relative, the Japanese medaka: the AHR molecular mechanism
揭示未特征化的NSP结构和功能意义以及在哺乳动物和非哺乳动物动脉病毒分子工具包中的变异	Rakesh, S.	PDF	N/A	Uncovering the Structural and Functional Implications of Uncharacterized NSPs and Variations in the Molecular Toolkit Across Mammalian and Non-Mammalian Arteriviruses
识别潜在人群特征对风险因素的效应修饰作用：基于稀疏变化的系数回归	Wang, R.	PDF	N/A	Identifying Effect Modification of Latent Population Characteristics on Risk Factors with a Sparse Varying Coefficient Regression
通过快速进化的免疫开关实现Argonaute的动态调控	Ewe, C. K.	PDF	N/A	Dynamic Control of Argonautes by a Rapidly Evolving Immunological Switch
人类下肢活动信号提取与分类的肌音图研究	Bai, Y.	PDF	N/A	An Investigation into Mechanomyography for Signal Extraction and Classification of Human Lower Limb Activity
使用量子退火进行多序列比对的可扩展引导树构建	Park, Y.	PDF	N/A	Scalable Guide Tree Construction Using Quantum Annealing for Multiple Sequence Alignment
自动细胞类型注释与参考簇映射	Galanti, V.	PDF	N/A	Automated Cell Type Annotation with Reference Cluster Mapping
使用预训练的Transformer模型预测肿瘤基因表达的组织来源	Mellors, T.	PDF	N/A	Predicting Tissue of Origin from Bulk Tumor Gene Expression using a Pre-trained Transformer Model
用于分析单细胞分辨率相互作用的稀疏降维	Brunn, N.	PDF	N/A	Sparse dimensionality reduction for analyzing single-cell-resolved interactions
本地单体型分类器能够实现高效、灵活且安全的基因型推断及下游分析	Cheema, M. N.	PDF	N/A	Local Haplotype Classifiers enable Efficient, Flexible, and Secure Genotype Imputation and Downstream Analyses
通过利用外显子组测序数据中的脱靶读取，识别与基因组特征相关的新基因和表型关联	Ercelen, D.	PDF	N/A	Identifying novel genetic and phenotypic associations to genomic features by leveraging off-target reads in exome sequencing data
氨基酸转移自由能揭示生物分子凝聚物形成的热力学驱动力	Rekhi, S.	PDF	N/A	Amino Acid Transfer Free Energies Reveal Thermodynamic Driving Forces in Biomolecular Condensate Formation
移动肌球蛋白马达驱动的集群形成与相分离在运动实验中的作用	Slater, B.	PDF	N/A	Cluster Formation and Phase Separation Driven by Mobile Myosin Motors in the Motility Assay
扩展质量（eQual）：基于n元相似性的径向阈值聚类	Chen, L.	PDF	N/A	Extended Quality (eQual): Radial threshold clustering based on n-ary similarity
α-突触核蛋白敲除损害了黑色素瘤的发展，并以性别依赖的方式改变了TG3小鼠模型中的DNA损伤修复	Arnold, M. R.	PDF	N/A	Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner
皮肤人乳头瘤病毒E6损害cGAS-STING通路	Tolbert, E.	PDF	N/A	Cutaneous human papillomavirus E6 impairs the cGAS-STING pathway
去甲基化药物对急性髓性白血病小鼠模型中白血病微环境基因调控及疾病进程的影响	Ebelt, N. D.	PDF	N/A	Effects of Hypomethylating Agents on Gene Modulation in the Leukemic Microenvironment and Disease Trajectory in a Mouse Model of AML
多组学分析揭示了鼻咽鳞状细胞癌中的恶性亚群及缺氧驱动的血管生成轴作为治疗脆弱性	You, C.	PDF	N/A	Multi-omic profiling identifies malignant subpopulations and a hypoxia-driven angiogenic axis as therapeutic vulnerabilities in sinonasal squamous cell carcinoma
腺病毒对IRE1α-XBP1信号通路的动态调控	Jang, Y.	PDF	N/A	Dynamic modulation of IRE1α-XBP1 signaling by adenovirus
空间单细胞转录组分析揭示了一种新型DICER1综合征小鼠模型（GEMM）的细胞起源及其相关肉瘤的发展层次	Kommoss, F. K.	PDF	N/A	Spatial single cell transcriptomic analysis of a novel DICER1 Syndrome GEMM informs the cellular origin and developmental hierarchy of associated sarcomas
脑老化过程中的微血管搏动及其在麻醉中的混杂效应	Skott, M. V.	PDF	N/A	Microvascular pulsatility of the ageing brain and confounding effects of anaesthesia
在心脏收缩功能受损的患者中，左心室停滞是由血流输送而非射血分数决定的。	Martinez-Legazpi, P.	PDF	N/A	Flow transport and not ejection fraction determines left ventricular stasis in patients with impaired systolic function
溪刺鱼（Culaea inconstans）栖息于中性及碱性湖泊中，其碱耐受性的种内差异	Zimmer, A. M.	PDF	N/A	Intraspecific differences in alkaline tolerance in brook stickleback (Culaea inconstans) inhabiting neutral and alkaline lakes
研究慢性短睡眠对新陈代谢和氧化应激生存的影响	Tener, S. J.	PDF	N/A	Investigating the consequences of chronic short sleep for metabolism and survival of oxidative stress
工蜂羽化后立即发生的代谢变化	Verbinnen, G.	PDF	N/A	Shifts in honeybee worker metabolism immediately post-eclosion
通过生长辅助正反馈的超弹道细胞间信号传导	Wang, M.	PDF	N/A	Hyperballistic intercellular signaling through growth assisted positive feedback
备忘录：一种微型备忘录传感器，利用精确的无细胞表达平台检测微RNA-RISC	Copeland, C. E.	PDF	N/A	MEMO: A Micro Memo Sensor Detecting microRNA-RISC using an Accurate Cell-Free Expression Platform
RNA结合蛋白调控生发中心B细胞的G2-M检查点	Salerno, F.	PDF	N/A	RNA-binding proteins control the G2-M checkpoint of the germinal centre B cell
协调数字化植物标本数据以增强生物多样性知识：为格陵兰植物区系创建更新清单。	Whitley, B. S.	PDF	N/A	Harmonising digitised herbarium data to enhance biodiversity knowledge: creating an updated checklist for the flora of Greenland.
渔业监测还是鱼类监测？尽管存在保护危机，三文鱼产卵监测的减少仍在持续	Atkinson, E. M.	PDF	N/A	Monitoring for fisheries or for fish? Declines in monitoring of salmon spawners continue despite a conservation crisis
高频鸣叫蟋蟀（Eneopterinae）前翅超微结构的比较研究	ROYER, L.	PDF	N/A	Comparative forewing ultrastructure of high-frequency singing crickets (Eneopterinae)
即使在实际温度没有变化的情况下，对温度的感知也足以驱动跨代表观遗传的遗传。	Teichman, G.	PDF	N/A	Perception of Temperature Even in the Absence of Actual Change is Sufficient to Drive Transgenerational Epigenetic Inheritance
人类真菌病原体新生隐球菌交配型位点编码的关键基因	Bian, Z.	PDF	N/A	Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans
多维变量剂量分析（mVDA）是一种用于高通量绘制遗传相互作用的新方法。	Sengupta, S.	PDF	N/A	Multidimensional variable dose analysis (mVDA) is a novel method for high-throughput mapping of genetic interactions
增强果蝇细胞遗传检测的方法	Wang, Y.	PDF	N/A	Enhanced methods for genetic assays in Drosophila cells
一个解析谱系的多模态单细胞图谱揭示了早期秀丽隐杆线虫发育的基因组动力学	van der Burght, S. N.	PDF	N/A	A lineage-resolved multimodal single-cell atlas reveals the genomic dynamics of early C. elegans development
一种用于在Cauloacter crescentus中高效快速进行基因组编辑的CRISPR/SpCas9M-报告系统	Sun, J.	PDF	N/A	A CRISPR/SpCas9M-reporting system for efficient and rapid genome editing in Caulobacter crescentus
在蛋白质结构标记器中平衡局部性与重构性	Meynard-Piganeau, B.	PDF	N/A	Balancing Locality and Reconstruction in Protein Structure Tokenizer
CellSexID：基于性别的嵌合模型细胞起源计算追踪	Tai, H.	PDF	N/A	CellSexID: Sex-Based Computational Tracking of Cellular Origins in Chimeric Models
ProtSpace：一种用于可视化蛋白质空间的工具	Senoner, T.	PDF	N/A	ProtSpace: a tool for visualizing protein space
一种从低覆盖率测序数据中进行常见变异基因分型的高效新算法	Zhang, S.	PDF	N/A	A Novel Efficient Algorithm for Common Variants Genotyping from Low-Coverage Sequencing Data
准确的通用DNA表征在基因组基础模型的大规模应用中显现	Ellington, C. N.	PDF	N/A	Accurate and General DNA Representations Emerge from Genome Foundation Models at Scale
RNA-DNA和DNA-DNA相互作用组的联合分析揭示了它们之间的强关联性。	Zvezdin, D. S.	PDF	N/A	Joint analysis of RNA-DNA and DNA-DNA interactomes reveals their strong association
人牛磺酸转运蛋白TauT的结构揭示了底物识别与抑制机制	lu, Y.	PDF	N/A	Structure of the human taurine transporter TauT reveals substrate recognition and mechanisms of inhibition
将分子尺度与细胞尺度相结合，用于膜受体信号传导模型	Peterson, K. J.	PDF	N/A	Bridging molecular to cellular scales for models of membrane receptor signaling
DNA张力计揭示了驱动蛋白-1、-2和-3的捕获键解离动力学	Noell, C. R.	PDF	N/A	DNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2 and -3
电压门控钙通道失调可能参与钙调蛋白病神经症状的发生	Hussey, J. W.	PDF	N/A	Voltage Gated Calcium Channel Dysregulation May Contribute to Neurological Symptoms in Calmodulinopathies
力场极化对蛋白质集体运动的影响	Milinski, A.	PDF	N/A	Impact of force field polarization on the collective motions of proteins
靶细胞张力调控巨噬细胞吞噬作用	Cornell, C. E.	PDF	N/A	Target cell tension regulates macrophage trogocytosis
IFNγ依赖的代谢重编程抑制了黑色素瘤中不成熟、促转移的淋巴状态。	Karakousi, T.	PDF	N/A	IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma
解析由免疫系统控制的休眠转移的表型	Chamorro, V.	PDF	N/A	Unraveling the Phenotype of Dormant Metastases Controlled by the Immune System
氧化还原催化亚基冗余性使N-糖基化的治疗靶向成为可能	Baro, M.	PDF	N/A	OST Catalytic Subunit Redundancy Enables Therapeutic Targeting of N-Glycosylation
系统生物学引导的NF-κB和BCL2靶向克服了DLBCL中微环境介导的BH3模拟物耐药性。	Vareli, A.	PDF	N/A	Systems biology-enabled targeting of NF-κB and BCL2 overcomes microenvironment-mediated BH3-mimetic resistance in DLBCL.
源自患者的肝细胞癌（HCC）细胞再现了与原发性HCV相关肝癌的转录组特征。	Kah, J.	PDF	N/A	Patient-derived HCC cells recapitulating the transcriptomic landscape of primary HCV-related liver cancer
大麻二酚促进细胞凋亡并下调致癌因子	Greenwood, A. L.	PDF	N/A	Cannabidiol promotes apoptosis and downregulation of oncogenic factors
节食通过诱导持久的肠道菌群失调，使小鼠的摄食行为失调。	Fouesnard, M.	PDF	N/A	Yo-yo dieting deregulates feeding behavior in mice via the induction of durable gut dysbiosis
哺乳至断奶过渡期间肠道上皮转录组变化的单细胞图谱	Malonga, T.	PDF	N/A	A single-cell atlas of transcriptome changes in the intestinal epithelium at the suckling-to-weaning transition
在内在无序的转录激活域中，功能保守而氨基酸序列不保守	LeBlanc, C. J.	PDF	N/A	Conservation of function without conservation of amino acid sequence in intrinsically disordered transcriptional activation domains
发现独立调控健康寿命和最大寿命的热力学控制变量	Denisov, K. A.	PDF	N/A	Discovery of Thermodynamic Control Variables that Independently Regulate Healthspan and Maximum Lifespan
异常的eNK细胞在宫腔粘连患者中促进子宫内膜纤维化	Zhou, Z.	PDF	N/A	Abnormal eNK cells contribute to endometrial fibrosis in intrauterine adhesions patients
细胞因子动态与氧化应激在宿主细胞中对耐药和敏感结核分枝杆菌分离株的刺激反应	Kumar, K.	PDF	N/A	Cytokine Dynamics and Oxidative Stress in Host Cells Stimulated with Drug-Resistant and Sensitive Mycobacterium tuberculosis Isolates
人免疫系统人源化-DRAGA小鼠是一个有价值的研究新型HIV-1免疫疗法的模型。	Pumtang-on, P.	PDF	N/A	Human-immune-system humanized-DRAGA mice are a valuable model to study novel immunotherapies for HIV-1
多花紫藤凝集素通过与扎伊尔埃博拉病毒糖蛋白复合物上特定N-连接糖基化位点的相互作用，增强了病毒的进入过程。	Duncan, J. D.	PDF	N/A	Wisteria floribunda agglutinin enhances Zaire ebolavirus entry through interactions at specific N-linked glycosylation sites on the virus glycoprotein complex
有颌脊椎动物（Gnathostomata）胃的进化：通过基因组损失的研究——来自无胃物种的发现	Dann, J. B.	PDF	N/A	Evolution of the Jawed Vertebrate (Gnathostomata) Stomach through Gene Repertoire Loss: Findings from Agastric Species
热感受神经元通过调节生殖系转座子来控制遗传继承。	Szanto, P.	PDF	N/A	Thermosensory neurons control genetic inheritance through regulation of germline transposons
三种入侵昆虫的基因组草图及转录组序列数据	Lombaert, E.	PDF	N/A	Draft genome and transcriptomic sequence data of three invasive insect species
糖尿病预防计划研究中的糖尿病前期表型聚类	Stroebel, B. M.	PDF	N/A	Prediabetes Phenotype Clusters in the Diabetes Prevention Program Study
时间通过CpG位点簇的甲基化变化进行编码	Ochana, B.-L.	PDF	N/A	Time is encoded by methylation changes at clustered CpG sites
阿尔茨海默病中单细胞水平上性别和APOE基因型特异性转录变化的风貌	Yu, G.	PDF	N/A	The Landscape of Sex- and APOE Genotype-Specific Transcriptional Changes in Alzheimer's Disease at the Single Cell Level
一种极简主义的二进制/数字方法，利用光学标记的tRNAs和多种羧肽酶进行大规模单分子蛋白质鉴定，并将其扩展到肽段测序。	Sampath, G.	PDF	N/A	A minimalist binary/digital approach to large-scale single molecule protein identification with optically labeled tRNAs and multiple carboxypeptidases and its extension to peptide sequencing
可以使用耳内和耳周的脑电极来估计言语接受阈值。	Borges, H. B.	PDF	N/A	The Speech Reception Threshold Can be Estimated Using EEG Electrodes In and Around the Ear
人诱导多能干细胞衍生的运动神经支配增强了使用桌面制造技术工程化的肌肉束的分化	Santoso, J. W.	PDF	N/A	Human iPSC-derived motor neuron innervation enhances the differentiation of muscle bundles engineered with benchtop fabrication techniques
abCAN：一种实用且新颖的注意力网络，用于预测突变抗体亲和力	Gong, C.	PDF	N/A	abCAN: a Practical and Novel Attention Network for Predicting Mutant Antibody Affinity
负二项隐因子模型用于配对微生物组测序数据	Kim, H.	PDF	N/A	A negative binomial latent factor model for paired microbiome sequencing data
缓解光谱学揭示了贝达喹啉在活体分枝杆菌中的作用机制	Harrison, S. H.	PDF	N/A	Remission spectroscopy resolves the mode of action of bedaquiline within living mycobacteria
Q/R编辑和选择性过滤器突变对GluA2 AMPA受体钙通透性原子机制的调节	Heiser, F.	PDF	N/A	Atomistic Mechanisms of Calcium Permeation Modulated by Q/R Editing and Selectivity Filter Mutations in GluA2 AMPA Receptors
通过细胞外基质（ECM）进行的机械通信依赖于频率，这是由于细胞对机械信号形状的敏感性所致。	Nitsan, I.	PDF	N/A	Mechanical communication through the ECM is frequency-dependent due to cell sensitivity to mechanical signal shape
蛋白质-蛋白质界面中的挫败感在PROTAC三元复合物的协同作用中起着核心作用	Ma, N.	PDF	N/A	Frustration in the Protein-Protein interface Plays a Central Role in the Cooperativity of PROTAC Ternary Complexes
堂娜·弗洛尔和她的两个丈夫：发现新型HDAC6/AKT2抑制剂用于髓系癌症治疗	Waitman, K. B.	PDF	N/A	Dona Flor and her two husbands: Discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment
对立谱系调控因子诱导肺腺癌中的促肿瘤混合身份状态	Fort, G.	PDF	N/A	Opposing lineage specifiers induce a pro-tumor hybrid-identity state in lung adenocarcinoma
MOZ和HBO1组蛋白乙酰转移酶复合物是NUP98重排急性髓系白血病的分子依赖性和治疗靶点	Mullighan, C. G.	PDF	N/A	MOZ and HBO1 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia
环状RNA - circCLIP2主要在胶质母细胞瘤干细胞（GSC）微环境中表达，并通过上皮间质转化（EMT）和细胞外基质（ECM）信号传导途径增强胶质母细胞瘤的侵袭性。	Misiorek, J. O.	PDF	N/A	Circular RNA - circCLIP2 is predominantly expressed in GSC niche and enhances glioblastoma aggressiveness via EMT and ECM signaling
Gankyrin/PSMD10下调影响胶质母细胞瘤中癌细胞的生长和增殖：体外和体内研究	Travnikova, D.	PDF	N/A	Downregulation of Gankyrin/PSMD10 affects cancer cell growth and proliferation in glioblastoma: in vitro and in vivo study
通过超快化学蛋白质组学研究Pt(IV)与氯尼达明配体的作用机制	Imaikina, E. A..	PDF	N/A	Study on the mechanism of action of the Pt(IV) complex with lonidamine ligands by ultrafast chemical proteomics
表型分析隐藏的一半：结合无人机表型分析和机器学习预测田间大麦根系性状	Alahmad, S.	PDF	N/A	Phenotyping the hidden half: Combining UAV phenotyping and machine learning to predict barley root traits in the field
探究DI-DII连接子在Nav1.5通道功能中的作用	Wagner, E.	PDF	N/A	Investigating the Functional Role of the DI-DII Linker in Nav1.5 Channel Function
在棕色脂肪细胞特异性缺失ATGL和HSL的情况下，非颤抖性产热功能保持完整，这可能是由于白色脂肪组织的棕色化作用。	Manandhar, Y.	PDF	N/A	Non-shivering thermogenesis is intact upon brown-adipocyte specific loss of ATGL and HSL due to white adipose tissue browning
外周人多形核白细胞激活和吞噬作用的高维光谱流式细胞术分析	Lamb, E. R.	PDF	N/A	High-dimensional spectral flow cytometry of activation and phagocytosis by peripheral human polymorphonuclear leukocytes
CD226+ 脂肪组织巨噬细胞源自MDP衍生的单核细胞，并调节脂质代谢。	Gallerand, A.	PDF	N/A	CD226+ adipose tissue macrophages arise from MDP-derived monocytes and regulate lipid metabolism.
单倍二倍性加速昆虫线粒体基因组进化	Pakrashi, A.	PDF	N/A	HAPLODIPOIDY ACCELERATES MITOGENOME EVOLUTION IN INSECTS
SynapseNet：深度学习在自动突触重建中的应用	Muth, S.	PDF	N/A	SynapseNet: Deep Learning for Automatic Synapse Reconstruction
负电荷基团在抗菌阳离子肽模拟物中的作用：对膜相互作用的深入理解	Saiba, R.	PDF	N/A	The Role of Negatively Charged Groups in Antimicrobial Cationic Peptide Mimics: Insights into Membrane Interactions
语言复杂性在听觉和言语刺激神经处理中的时间性和半球动态变化：一项MEG源空间研究	Krauss, P.	PDF	N/A	Temporal and Hemispheric Dynamics in Neural Processing of Auditory and Speech Stimuli Across Linguistic Complexity: A MEG Source Space Study
利用结合的脑电图（EEG）和脑磁图（MEG）测量分析人类大脑中处理名词和动词的差异	Koelbl, N.	PDF	N/A	Analyzing Differences in Processing Nouns and Verbs in the Human Brain using Combined EEG and MEG Measurements
GET3B与类囊体ALB3和ALB4插入酶相互作用，并参与叶绿体生物发生的初始阶段。	Bodensohn, U.	PDF	N/A	GET3B interacts with the thylakoidal ALB3 and ALB4 insertases and is involved in the initial stages of chloroplast biogenesis
通过hTERT使间充质基质细胞永生化，不会影响分泌的外泌体的功能特性。	Brancolini, A.	PDF	N/A	Immortalization of mesenchymal stromal cells by hTERT does not affect the functional properties of secreted extracellular vesicles
CENcyclopedia：细胞周期中着丝粒结构的动态景观	Chen, Y.-C.	PDF	N/A	CENcyclopedia: Dynamic Landscape of Kinetochore Architecture Throughout the Cell Cycle
TMEM251对GNPTAB调控的分子洞察	Yang, X.	PDF	N/A	Molecular Insights into the Regulation of GNPTAB by TMEM251
冲突的时间线：探索四足动物分歧估计中线粒体-核不一致的模式	Ranganathan, E.	PDF	N/A	Conflicting Timelines: Exploring patterns of mito-nuclear discordance in divergence estimates among tetrapods
用于脊髓损伤治疗的植入式3D打印多通道微通道	Grebenyuk, S.	PDF	N/A	Implantable 3D printed multiplexed microtunnels for spinal cord injury treatment
研究成纤维细胞靠近肿瘤对其胞外囊泡生成的影响，利用3D生物打印的基质模型	Amens, J. N.	PDF	N/A	Investigating the impact of fibroblast proximity to a tumor on fibroblast extracellular vesicle production utilizing 3D bioprinted stromal models
用于免疫防御创伤性脑损伤的疫苗	Acharya, A. P.	PDF	N/A	Vaccines for immunological defense against traumatic brain injury
用于检测HG002 Genome In A Bottle NIST参考材料中低频变异体的稳健基准。	Daniels, C.	PDF	N/A	A robust benchmark for detecting low-frequency variants in the HG002 Genome In A Bottle NIST reference material.
CoLaML：从异质基因内容中推断潜在的进化模式	Yamanouchi, S.	PDF	N/A	CoLaML: Inferring latent evolutionary modes from heterogeneous gene content
用于蛋白质结构预测的检索增强蛋白质语言模型	Li, P.	PDF	N/A	Retrieval Augmented Protein Language Models for Protein Structure Prediction
使用机器学习预测小分子抗菌药物类别特异性	Gadiya, Y.	PDF	N/A	Predicting antimicrobial class specificity of small molecules using machine learning
GAPDH的RNA结合调控急性髓系白血病中转录本的稳定性和蛋白质翻译	Imig, J.	PDF	N/A	RNA Binding of GAPDH Controls Transcript Stability and Protein Translation in Acute Myeloid Leukemia
多灶性小肠神经内分泌肿瘤的表观遗传学研究揭示了肿瘤加速老化及代谢基因的表观遗传学改变	Webster, A. P.	PDF	N/A	Epigenetic investigation of multifocal small intestinal neuroendocrine tumours reveals accelerated ageing of tumours and epigenetic alteration of metabolic genes
在离体猪角膜感染模型中，使用管道环稳定地局部应用抗菌药物	Foulkes, D. M.	PDF	N/A	Stable topical application of antimicrobials using plumbing rings in an ex vivo porcine corneal infection model
心肌梗死后11β羟基类固醇脱氢酶1型药理学抑制作用靶向外基质加工，并在小型猪模型中保护心脏功能	Al Disi, S.	PDF	N/A	Pharmacological inhibition of 11βhydroxysteroid dehydrogenase type 1 after myocardial infarction targets extracellular matrix processing and preserves cardiac function in a translational mini-pig model
ROSLT：一种改进的树莓派开源实时自愿轮跑追踪方法和资源	Sanosa, P.	PDF	N/A	ROSLT: An Improved Raspberry-Pi Open-Source Live Voluntary-Wheel Running Tracker Method and Resource
DoRIAT：一种用于解释和注释对接运行的贝叶斯框架。	Maniatis, C.	PDF	N/A	DoRIAT: A Bayesian Framework For Interpreting And Annotating Docking Runs.
利用Immunemap这一开放的活体显微镜图谱，对免疫细胞运动进行系统分析	Pizzagalli, D. U.	PDF	N/A	Systematic analysis of immune cell motility leveraging Immunemap, an open intravital microscopy atlas
巴西跳蚤科（半翅目：瘿蚜总科：瘿蚜科）中的Paurocephalini族跳蚤	Serbina, L.	PDF	N/A	Jumping plant-lice of the tribe Paurocephalini (Hemiptera: Psylloidea: Liviidae) in Brazil
果蝇大脑中已鉴定神经元的突触图谱分析	Wu, H.	PDF	N/A	Synapse profiling of identified neurons in the Drosophila brain
章鱼胺信号协调果蝇蘑菇体内突触前机制的空间模式	Wu, H.	PDF	N/A	Octopamine signals coordinate the spatial pattern of presynaptic machineries in the Drosophila mushroom bodies
新诊断类风湿性关节炎患者和健康当前吸烟者对照组支气管肺泡灌洗细胞HLA-DR免疫肽组学的特征	Zohrer, B.	PDF	N/A	Characterization of HLA-DR immunopeptidome of bronchoalveolar lavage cells in patients with newly diagnosed rheumatoid arthritis and healthy current-smoker controls
设计多型登革病毒疫苗：一种基于计算机的方法实现广谱免疫	Singh, A.	PDF	N/A	Designing a multi-serotype Dengue virus vaccine: an in silico approach to broad-spectrum immunity
揭示分层淡水湖中军团菌的生态：季节动态、宿主相互作用及在氧气有限条件下的持久性	Bergman, O.	PDF	N/A	Unveiling the Ecology of Legionella in a Stratified Freshwater Lake: Seasonal Dynamics, Host Interactions, and Persistence Under Oxygen Limited Conditions
被忽视的捕食性昆虫在濒危沿海栖息地中触发了潜在的关键生物多样性区域	Ascenzi, A.	PDF	N/A	Neglected predatory insects trigger potential Key Biodiversity Areas in threatened coastal habitats
海胆花属（Penstemon）中具人形花的独特形态基础及其平行演化历史	Depatie, T. H.	PDF	N/A	The unique morphological basis and parallel evolutionary history of personate flowers in Penstemon
基于系统发育的方法在灵长类动物中探索突变过程	Kitch, J. C.	PDF	N/A	A Phylogeny-Based Approach to Discover Mutational Processes in Primates
形态上不同的群体是否对应于生殖隔离的物种？瑞士红蚁的一个案例研究	Lavanchy, G.	PDF	N/A	Do morphologically distinct groups correspond to reproductively isolated species? A case study in Myrmica ants from Switzerland
揭示甜菜驯化和育种中的关键基因	Dhiman, A. S.	PDF	N/A	Uncovering Genes Essential in Domestication and Breeding of Sugar Beet
基于Cas9的富集用于靶向长读段元条形码分析	Nikolaeva-Reynolds, L.	PDF	N/A	Cas9-based enrichment for targeted long-read metabarcoding
ERGA-BGE 参考基因组：来自伊比利亚干旱地区的特有鞭蛛	Lozano-Fernandez, J.	PDF	N/A	ERGA-BGE Reference Genome of Gluvia dorsalis: An Endemic Sun Spider from Iberian Arid Regions
RpiBeh：一种多用途的开源解决方案，用于实时追踪和基于行为的小鼠神经行为学闭环干预	Sun, Y.	PDF	N/A	RpiBeh: a multi-purpose open-source solution for real-time tracking and behavior-driven closed-loop interventions in rodent neuroethology
从仅包含序列的训练数据生成全原子蛋白质结构	Lu, A. X.	PDF	N/A	Generating All-Atom Protein Structure from Sequence-Only Training Data
TROP2/Claudin程序介导免疫排斥，阻碍乳腺癌中的检查点阻断	Wu, B.	PDF	N/A	A TROP2/Claudin Program Mediates Immune Exclusion to Impede Checkpoint Blockade in Breast Cancer
适应性复制原点激活改变了癌细胞中的染色质动力学和稳定性	Perez-Venteo, A.	PDF	N/A	Adaptive replication origin activation alters chromatin dynamics and stability in cancer cells
泛素连接酶ITCH调控SARS-CoV-2病毒的生命周期	Xiang, Q.	PDF	N/A	Ubiquitin Ligase ITCH Regulates Life Cycle of SARS-CoV-2 Virus
胶囊和遗传背景，而非特定基因座，对肺炎球菌生长动力学有强烈影响。	Chaguza, C.	PDF	N/A	The capsule and genetic background, rather than specific loci, strongly influence pneumococcal growth kinetics
痘病毒编码的E3样蛋白的差异可以决定痘病毒激活细胞坏死性凋亡	Enow, J. A.	PDF	N/A	Divergence in poxvirus-encoded E3-like proteins can dictate poxvirus activation of cellular necroptosis
对来自Mastomys natalensis的三种巨细胞病毒的分子克隆及宿主范围分析	Staliunaite, L.	PDF	N/A	Molecular cloning and host range analysis of three cytomegaloviruses from Mastomys natalensis
DynaMAP：通过高密度光学图谱进行动态微生物组丰度分析	Abakumov, S.	PDF	N/A	DynaMAP: Dynamic Microbiome Abundance Profiling through high density optical mapping
全基因组序列、代谢谱分析及功能研究揭示，Ligilactobacillus salivarius LS-ARS2是一种具有显著抗氧化、抗菌及抗生物膜潜能的生物膜形成型益生菌，显示出良好的应用前景。	Patra, S.	PDF	N/A	Complete Genome Sequence, Metabolic Profiling and Functional Studies reveal Ligilactobacillus salivarius LS-ARS2 is a Promising Biofilm-forming Probiotic with Significant Antioxidant, Antibacterial, and Antibiofilm Potential
有袋类动物肠道微生物组的宏基因组分析为低甲烷经济提供了遗传基础。	Bowerman, K. L.	PDF	N/A	Metagenomic analysis of marsupial gut microbiomes provides a genetic basis for the low methane economy
肠道微生物群物种Levilactobacillus brevis调节秀丽隐杆线虫的生殖适应性	Braun, N. J.	PDF	N/A	Gut microbiome species Levilactobacillus brevis regulates reproductive fitness in C. elegans
对原噬菌体激活的进化响应减弱了可培养的蚜虫内共生菌Serratia symbiotica相关菌株的毒力。	VanDieren, A. J.	PDF	N/A	Evolution in response to prophage activation attenuates the virulence of culturable Serratia symbiotica relatives of aphid endosymbionts
实验性噬菌体进化导致对多重耐药和广泛耐药肺炎克雷伯菌分离株的宿主范围扩大	Ghatbale, P.	PDF	N/A	Experimental Phage Evolution Results in Expanded Host Ranges Against MDR and XDR Klebsiella pneumoniae Isolates
优化人源单克隆抗体以增强对SARS-CoV-2的中和作用	Wang, Q.	PDF	N/A	Optimizing a Human Monoclonal Antibody for Better Neutralization of SARS-CoV-2
E-box独立染色质招募使MYOD转变为转录抑制因子	Nicoletti, C.	PDF	N/A	E-box independent chromatin recruitment turns MYOD into a transcriptional repressor
高通量表观遗传学分析免疫检测法，助力加速疾病研究和临床开发	Van den Ackerveken, P.	PDF	N/A	High-Throughput Epigenetic Profiling Immunoassays for Accelerated Disease Research and Clinical Development
工程化一种受炭疽毒素启发的蛋白质-配体，用于纳米颗粒介导的恶性黑色素瘤治疗	Marquez-Lopez, A.	PDF	N/A	Engineering an Anthrax Toxin inspired protein-ligand for Nanoparticle-Mediated Treatment of Malignant Melanoma
超过一半的注释人类miRNAs在表达水平上不足以执行其生物学功能。	Kachooei, S. A.	PDF	N/A	More than half of annotated human miRNAs are never expressed at levels sufficient for biological function
Rad52通过一个大的C端85残基片段作为装配陪伴蛋白来形成和稳定Rad51纤维	Ma, E.	PDF	N/A	Rad52 Acts as an Assembly Chaperone to Form and Stabilize Rad51 Filaments Through a Large C-Terminus 85-Residue Segment
Prp16能够高效剪接富含短内含子的隐球菌转录组中具有多样外显子一致性元件的内含子。	Negi, M. S.	PDF	N/A	Prp16 enables efficient splicing of introns with diverse exonic consensus elements in the short-intron rich Cryptococcus neoformans transcriptome
高通量定量miRNA-3'-非翻译区调控效应	Ding, Y.	PDF	N/A	High-Throughput Quantification of miRNA-3'-Untranslated-Region Regulatory Effects
使用斑马鱼hand2 Cre和CreERT2重组酶的CRISPR敲入进行谱系标记	Ming, Z.	PDF	N/A	Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock-ins
药理浓度的维生素C能抑制髓过氧化物酶产生的次氯酸，而氧化态的维生素C则能抑制关键的硫醇蛋白并抑制Jurkat细胞的生长。	Peskin, A. V.	PDF	N/A	Pharmacological concentrations of vitamin C inhibit hypochlorous acid generation by myeloperoxidase, and oxidized vitamin C inhibits critical thiol proteins and growth of Jurkat cells
Tau中天冬氨酸的异常快速异构化	Shoff, T. A.	PDF	N/A	Unusually Rapid Isomerization of Aspartic Acid in Tau
噼啪云：一种基于事件驱动的云端CRISPR-Cas9引导RNA设计工具	Bradford, J.	PDF	N/A	Crackling Cloud: an event-driven, cloud-based CRISPR-Cas9 guide RNA design tool
可扩展的深度生成学习模拟蛋白质平衡系综	Lewis, S.	PDF	N/A	Scalable emulation of protein equilibrium ensembles with generative deep learning
全面网络分析miRNA生物发生蛋白及其配体相互作用位点以识别癌症治疗的新靶点	Almhanna, H.	PDF	N/A	Comprehensive Network Analysis of miRNA Biogenesis Proteins and Their Ligand Interaction Sites to Identify Novel Targets for Cancer Therapeutics
铜绿假单胞菌PA14鞭毛介导的表面感应的遗传分析	Kuchma, S.	PDF	N/A	Genetic Analysis of Flagellar-Mediated Surface Sensing by Pseudomonas aeruginosa PA14
缺乏多种氨基酸转运蛋白的酿酒酵母菌株的特性分析与全基因组测序：研究氨基酸转运的工具	Sonawala, U.	PDF	N/A	Characterization and whole genome sequencing of Saccharomyces cerevisiae strains lacking several amino acid transporters: tools for studying amino acid transport
抗VCAM-1抗体的分离与表征揭示了Ig样结构域2和3在细胞间相互作用中的潜在作用	Perera, B.	PDF	N/A	Isolation and Characterization of Antibodies Against VCAM-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell Interaction
CTP结合基序对S. coelicolor ParB与DNA、染色体分离及孢子形成菌丝生长的相互作用的重要性。	Szymczak, J.	PDF	N/A	Significance of the CTP-binding motif for the interactions of S. coelicolor ParB with DNA, chromosome segregation and sporogenic hyphal growth.
冷冻电镜显示，源自心脏IGLV6的AL纤维可以具有多态性。	Bassett, P. T.	PDF	N/A	Cryo-EM reveals that cardiac IGLV6-derived AL fibrils can be polymorphic
高通量分化人类血管类器官揭示脑静脉畸形蛋白的重叠与独特功能	Skowronek, D.	PDF	N/A	High-throughput differentiation of human blood vessel organoids reveals overlapping and distinct functions of the cerebral cavernous malformation proteins
针对基因剪接的靶向阻断可能会扰乱内含子嵌入的微小RNA的调控。	Ali, M. H.	PDF	N/A	Targeted blocking of gene splicing can dysregulate intron-embedded microRNAs
# BioRxiv 2024-12-04 Papers

标题	作者	PDF链接	代码仓库	Title
解密老年听众在噪声环境下的受损语音可懂度：耳蜗突触病变的作用	Garrett, M.	PDF	N/A	Deciphering compromised speech-in-noise intelligibility in older listeners: the role of cochlear synaptopathy
惰性原发性皮肤B细胞淋巴瘤类似于持续的抗原反应，没有分化不良的迹象。	Griss, J.	PDF	N/A	Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation
淀粉样蛋白β诱导脂滴介导的阿尔茨海默病中微胶质细胞功能障碍	Prakash, P.	PDF	N/A	Amyloid beta Induces Lipid Droplet-Mediated Microglial Dysfunction in Alzheimer's Disease
小鼠皮层培养中微型兴奋性突触后电流的稳态突触可塑性需要神经元Rab3A。	Koesters, A. G.	PDF	N/A	Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A.
DeepCristae是一种用于修复活体显微镜图像中线粒体嵴的卷积神经网络。	Papereux, S.	PDF	N/A	DeepCristae, a CNN for the restoration of mitochondria cristae in live microscopy images
视觉工作记忆的稀疏空间支架	Liu, B.	PDF	N/A	Sparse spatial scaffolding for visual working memory
ZC3H11A突变通过触发PI3K-AKT和NF-κB介导的信号通路，导致人类和小鼠的高度近视。	Chen, C.	PDF	N/A	ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice
数据转换和模型选择对微生物组分类数据特征重要性的影响	Org, E.	PDF	N/A	Effects of Data Transformation and Model Selection on Feature Importance in Microbiome Classification Data
圈养与野生鼩鼱大脑基因表达的比较揭示了圈养的影响	Bedoya Duque, M. A.	PDF	N/A	Gene expression comparisons between captive and wild shrew brains reveal captivity effects
将结核病基因组学引入临床：一个全面的流程，用于从基因组数据预测抗菌药物敏感性，经过ISO标准验证和认证。	Horan, K.	PDF	N/A	Bringing TB genomics to the clinic: A comprehensive pipeline to predict antimicrobial susceptibility from genomic data, validated and accredited to ISO standards.
肠道病毒71通过激活储存操纵性钙离子通道和线粒体呼吸作用，对高效病毒复制至关重要。	Hsu, B.-Y.	PDF	N/A	Activation of Store-Operated Calcium Entry and Mitochondiral Respiration by Enterovirus 71 Is Essential for Efficient Virus Replication
内体-溶酶体器组装（ELYSA）结构通过哺乳动物卵母细胞到胚胎的转变协调溶酶体降解系统。	Satouh, Y.	PDF	N/A	Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition
听觉刺激通过调节阿尔法波段的振荡，延长了视觉整合的时间窗口。	Xu, M.	PDF	N/A	Auditory stimuli extend the temporal window of visual integration by modulating alpha-band oscillations
利用机制性序列信息提升蛋白质表达模型的泛化能力	Shen, Y.	PDF	N/A	Improving the generalization of protein expression models with mechanistic sequence information
拟南芥对波动光的感知	Belmonte, A.	PDF	N/A	Sensory perception of fluctuating light in Arabidopsis
Tribus：从多重成像和蛋白质组数据中半自动化发现细胞身份和表型	Kang, Z.	PDF	N/A	Tribus: Semi-automated discovery of cell identities and phenotypes from multiplexed imaging and proteomicdata
辅助感觉运动扰动影响已学习的神经表征	Rajeswaran, P.	PDF	N/A	Assistive sensory-motor perturbations influence learned neural representations
简单的壳体测量并不能一致地预测龟类的栖息地：对Lichtig和Lucas（2017）的回应	Evers, S. W.	PDF	N/A	Simple shell measurements do not consistently predict habitat in turtles: a reply to Lichtig and Lucas (2017)
一种营养依赖型的天蓝色链霉菌觅食表型表现出增强的抗菌活性，并在该属中普遍存在。	Soderholm, N.	PDF	N/A	A nutrient-dependent foraging phenotype of S. coelicolor exhibits enhanced antimicrobial activity and is common across the genus
SLC13A2转运的柠檬酸是PKM2乙酰化和降解的代谢信号，以抑制肿瘤生长。	Xiong, J.	PDF	N/A	SLC13A2-transported citrate is a metabolic signal for PKM2 acetylation and degradation to suppress tumor growth
COEXIST：协调的单细胞级联多重组织图像整合	Heussner, R. T.	PDF	N/A	COEXIST: Coordinated single-cell integration of serial multiplexed tissue images
多种毒素表现出与烟碱型乙酰胆碱受体的共同结合模式	Do, H. N.	PDF	N/A	Diverse toxins exhibit a common binding mode to the Nicotinic Acetylcholine Receptors
惊悚的听觉刺激通过加强，而非改变时间，加速了反射性选择伸手任务中的快速视觉运动反应。	Weerdesteyn, V.	PDF	N/A	Startling acoustic stimuli hasten reflexive choice reaching tasks by strengthening, but not changing the timing of, express visuomotor responses
聚（烯丙胺）/三聚磷酸盐纳米复合凝聚物作为疫苗开发中依赖NLRP3的系统性佐剂	Rizzo, G. P.	PDF	N/A	Poly(allylamine)/tripolyphosphate nanocomplex coacervate as a NLRP3-dependent systemic adjuvant for vaccine development
利用计算机化飞行磨机研究栎树相关郭公甲科（鞘翅目：郭公甲科）飞行性能的种内和种间变异	Le Souchu, E.	PDF	N/A	Intra- and interspecific variations in flight performance of oak-associated Agrilinae (Coleoptera: Buprestidae) using computerised flight mills
内感受信号在猕猴的决策过程中产生偏差	Cardenas, M. A.	PDF	N/A	Interoceptive Signals Bias Decision Making in Rhesus Macaques
重复的外源性和各向异性机械输入促进极化黏着连接的延长	Yang, X.	PDF	N/A	Repeated extrinsic and anisotropic mechanical inputs promote polarized adherens junction elongation
转录组分析揭示了依赖DLK的海马谷氨酸能神经元退化的细胞网络	Ritchie, E. M.	PDF	N/A	Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration
膜结合B细胞受体组装的动态与激活	Do, H. N.	PDF	N/A	Dynamics and Activation of Membrane-Bound B Cell Receptor Assembly
杜氏肌营养不良症中的肌肉干细胞表现出分子损伤和细胞命运轨迹的改变，影响其再生能力。	Granet, J. A.	PDF	N/A	Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacity
鞘氨醇-1-磷酸信号通路调控穆勒胶质细胞转变为具有神经发生能力的增殖性前体样细胞的能力	Taylor, O.	PDF	N/A	Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells
交联琼脂糖-明胶珠作为研究细菌病原体生物膜的基质	Roizman, D.	PDF	N/A	Cross-linked agarose-gelatine beads as a substrate for investigating biofilms of bacterial pathogens
药物性CDK4/6抑制剂促进衰老相关的溶酶体改变，并增强乳腺癌对溶酶体增效剂的敏感性	Nehme, J.	PDF	N/A	Pharmacological CDK4/6 inhibitors promote senescence-associated lysosomal alterations and enhance sensitivity to lysosomotropic agents in breast cancer
FishPi：一种生物信息学预测工具，用于在斑马鱼中关联piRNA和转座元件	Godden, A. M.	PDF	N/A	FishPi: a bioinformatic prediction tool to link piRNA and transposable elements in zebrafish
陆地植物中依赖光的细胞核重新定位的开始	Iwabuchi, K.	PDF	N/A	The beginnings of light-dependent nuclear relocation in land plants
片足动物分泌细胞类型与摄食、先天免疫及行为调控相关	Mayorova, T. D.	PDF	N/A	Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior
空间多组学与SpaMosaic的马赛克整合	Yan, X.	PDF	N/A	Mosaic integration of spatial multi-omics with SpaMosaic
STRUCT：一种从原始测序数据中识别RNA二级结构的统计方法，无需进行多序列比对	Wang, J. F.	PDF	N/A	STRUCT: a statistical approach to identify RNA secondary structures from raw sequencing data, bypassing multiple sequence alignment
提高生成化学中分子字符串表示的可靠性	Reboul, E.	PDF	N/A	Improving the reliability of molecular string representations for generative chemistry
小麦白粉菌效应蛋白与杀伤蛋白UmV-KP4和UmV-KP6结构相关，对真菌具有毒性，并在真菌中定义了扩展的蛋白质家族。	de Guillen, K.	PDF	N/A	Zymoseptoria tritici effectors structurally related to killer proteins UmV-KP4 and UmV-KP6 are toxic to fungi, and define extended protein families in fungi
通过同时进行转录起始位点映射和甲基化定量来解码m6Am	Liu, J. F.	PDF	N/A	Decoding m6Am by simultaneous transcription-start mapping and methylation quantification
感觉运动整合增强了温度刺激处理	Anderson, L. S.	PDF	N/A	Sensorimotor integration enhances temperature stimulus processing
通过恢复衰老的骨祖细胞来促进骨修复	Reeves, J.	PDF	N/A	Rejuvenating aged osteoprogenitors for bone repair
在曲霉菌感染期间，IFN-STAT1-CYBB轴定义了保护性的浆细胞样DC与中性粒细胞之间的交叉对话。	Guo, Y.	PDF	N/A	An IFN-STAT1-CYBB Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk During Aspergillus fumigatus Infection.
组蛋白乙酰转移酶p300对RORβ的乙酰化以及SIRT1的去乙酰化作用，调控受体的稳定性、周转率及转录活性。	O'Leary, T. R.	PDF	N/A	Acetylation of RORβ by histone acetyltransferase p300 and deacetylation by SIRT1 modulates receptor stability, turnover and transcriptional activity.
TXNIP通过介导LAT1/SLC7A5的内吞作用，减少进入静止状态的细胞对氨基酸的摄取。	Kahlhofer, J.	PDF	N/A	TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence
几何扭曲在陷入棒状突触中减缓了谷氨酸的扩散并塑造了突触反应：来自解剖学上现实的蒙特卡罗模拟的见解	Thoreson, W. B.	PDF	N/A	Geometric tortuosity at invaginating rod synapses slows glutamate diffusion and shapes synaptic responses: insights from anatomically realistic Monte Carlo simulations
微生物裂解物作为细胞农业培养基配方中的低成本血清代用品	Dolgin, J.	PDF	N/A	Microbial lysates as low-cost serum replacements in cellular agriculture media formulation
岛屿人口结构：哥特兰标志性金雕的繁殖动态及其驱动因素	Singh, N. J.	PDF	N/A	Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles
不同年龄段在噪音环境下的语音感知：蒙古沙鼠与人类的比较研究	Jüchter, C.	PDF	N/A	Speech-in-noise perception across the lifespan: A comparative study in Mongolian gerbils and humans
具有自体组织驻留巨噬细胞的人类心脏类器官再现了生理性免疫-心脏相互作用	O'Hern, C.	PDF	N/A	Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions
一份关于真实植物来源的胞外囊泡的可靠参考标记物及其系统发育保守程度的纲要	Rodriguez de Lope, M. M.	PDF	N/A	A compendium of bona fide reference markers for genuine plant-derived extracellular vesicles and their degree of phylogenetic conservation
研究在光系统II中形成TyrD、TyrZ和QA*所引起的Soret区域电致变色带移	Boussac, A.	PDF	N/A	Investigation of electrochromic band-shifts in the Soret region induced by the formation of TyrD, TyrZ, and QA*- in Photosystem II
叶酸可预防草原田鼠因发育期接触拟除虫菊酯而导致的自闭症相关表型。	Saferin, N.	PDF	N/A	Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles
通过长程连接在皮层区域之间建立动态共识	Javadzadeh, M.	PDF	N/A	Dynamic consensus-building between neocortical areas via long-range connections
鉴定出一种由SARS-CoV2 S2蛋白衍生、具有超抗原样T细胞刺激特性的肽段	Tu, T. H.	PDF	N/A	The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells
遗传性出血性毛细血管扩张症2/Alk1在动脉内皮中的缺失导致鼻出血和脑微出血，伴有异常动脉和缺陷的平滑肌覆盖	Zhang, X.	PDF	N/A	Arterial endothelial deletion of hereditary hemorrhagic telangiectasia 2/Alk1 causes epistaxis and cerebral microhemorrhage with aberrant arteries and defective smooth muscle coverage
基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论计算碱基对结合能的结果	Deka, N.	PDF	N/A	Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT
4-甲基龙胆醇（4-MU）可改善大鼠脑缺血/再灌注损伤后的学习和记忆能力。	Tamouk, S.	PDF	N/A	4-Methyllumifrone (4-MU) can improve learning and memory after cerebral ischemia/reperfusion injury in rats
高级肽纳米颗粒能够实现基因编辑器在多种细胞类型中强效且高效的递送。	Gustafsson, O.	PDF	N/A	Advanced Peptide Nanoparticles Enable Robust and Efficient delivery of gene editors across cell types
一个评分统治一切：利用GWAS汇总统计数据进行正则化集合多基因风险预测	Zhao, Z.	PDF	N/A	One score to rule them all: regularized ensemble polygenic risk prediction with GWAS summary statistics
犬持续性苗勒管综合征：对AMH和AMHR2基因组织的新见解	Krzeminska, P.	PDF	N/A	Persistent Mullerian duct syndrome in dogs: a new insight into organization of AMH and AMHR2 genes
重塑乳腺癌肝转移局部治疗格局：一种新型瘤内p21靶向经皮疗法提高BALB/c小鼠接种4T1三阴性乳腺癌细胞后的生存率。	Margulies, B. S.	PDF	N/A	Reshaping the Landscape of Locoregional Treatments for Breast Cancer Liver Metastases: A novel, intratumoral, p21-targeted percutaneous therapy increases survival in BALB/c mice inoculated with 4T1 triple negative breast cancer cells in the liver.
使用12-6 Lennard-Jones势能模型模拟银(I)离子与蛋白质的相互作用：一种自下而上的参数化方法	Manciocchi, L.	PDF	N/A	Modelling the interaction between silver(I) ion and proteins with the 12-6 Lennard-Jones potential: a bottom-up parameterization approach
海藻糖促进埃及伊蚊细胞的生长，并调控基因表达和登革病毒复制。	Marten, A. D.	PDF	N/A	Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus replication
通过结合显式的交联信息来改进AlphaFold 3的结构建模	Kosinski, J.	PDF	N/A	Improving AlphaFold 3 structural modeling by incorporating explicit crosslinks
在专科神经精神病诊所中，血浆pTau181水平升高与阿片类药物使用相关，并在临床相关的时间尺度上指导药物剂量调整。	Hanson, E.	PDF	N/A	Elevated plasma pTau181 in a specialty neuropsychiatric clinic is associated with opioid use and guides medication titration on a clinically relevant short-time scale
呼吸阶段调节与视觉刺激相关的任务神经表征	Stetza, L.	PDF	N/A	The respiratory phase modulates task-related neural representations of visual stimuli
超越刺激起始：在自由观看过程中，物体内的持续注视不会重新唤起类别表征。	Auerbach-Asch, C. R.	PDF	N/A	Beyond stimulus onset: Ongoing fixations within an object do not re-evoke category representations during free-viewing.
情感内容影响视觉工作记忆的精确度	Haghian, Z.	PDF	N/A	Emotional content effects the precision of visual working memory
用于果蝇活体内单细胞标记和操控的稀疏驱动系统	Xu, C.	PDF	N/A	The sparse driver system for in vivo single-cell labeling and manipulation in Drosophila
颞叶癫痫主要表现为区域特异性的发作间期皮层抑制	Kienitz, R.	PDF	N/A	Temporal Lobe Epilepsy is dominated by Region Specific Interictal Cortical Inhibition
在韩国，小刺猬（Crocidura lasiura）中检测并描述了琅琊病毒	Natasha, A.	PDF	N/A	Detection and characterization of Langya virus in Crocidura lasiura, Republic of Korea
在韩国，检测并鉴定出朗格雅病毒存在于灰麝鼩（Crocidura lasiura）中。	Natasha, A.	PDF	N/A	Detection and characterization of Langya virus in Crocidura lasiura, Republic of Korea
逆转录转座子LINE1的反式调控分化过程维持胚胎干细胞特性	Ren, L.	PDF	N/A	Retrotransposon LINE1 trans-regulatory differentiation process maintain embryonic stem cell identity
人类细胞中基因低表达和高表达的形态图	Chandrasekaran, S. N.	PDF	N/A	Morphological map of under- and over-expression of genes in human cells
NJGPT：一种由大型语言模型驱动、用户友好的系统发育树构建解决方案	Wang, Z.	PDF	N/A	NJGPT: A Large Language Model-Driven, User-Friendly Solution for Phylogenetic Tree Construction
通过微喷雾器的通道增加功能活性——对时间分辨冷冻电镜活性测定的影响	Garg, P.	PDF	N/A	Passage through micro-sprayer increases functional activity-implications for activity assays in time-resolved cryo-EM
缺氧诱导因子驱动透明细胞肾癌中miRNA介导的L2HGDH和HIF1A下调，与14q缺失无关	Seal, S.	PDF	N/A	Hypoxia inducible factors drive miRNA-mediated downregulation of L2HGDH and HIF1A in clear cell renal cancer independent of 14q deletion
时间配置作为声音的新特征：心理和神经生理学证据，跨物种一致性及潜在的神经机制	Zhai, Y.	PDF	N/A	Temporal Configuration as a New Feature of Sound: Psychological and Neurophysiological Evidence, Cross-species Consistency and Underlying Neuronal Mechanisms
强迫性倾向个体在概率学习及更新预测表征中的个体差异	Brezoczki, B.	PDF	N/A	Individual differences in probabilistic learning and updating predictive representations in individuals with obsessive-compulsive tendencies
中国女性阴道微生态与炎症的关系研究。	Zhang, Y.	PDF	N/A	Vaginal Microbiome and Inflammation Among Chinese Women.
Tabula Sapiens揭示了28种人体器官和组织中细胞类型的转录因子表达、衰老效应和性别特异性特征。	The Tabula Sapiens Consortium,	PDF	N/A	Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissues
在诱导多能干细胞衍生的疾病模型中扩展GABA能神经元的多样性	Hu, R.	PDF	N/A	Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
从微观到宏观：鸟类染色体进化主要受自然选择驱动	Alfieri, J. M.	PDF	N/A	From Micro to Macro: Avian Chromosome Evolution is Dominated by Natural Selection
在听觉处理动物模型中描述早期生活压力的行为效应	Hardy, K. A.	PDF	N/A	Characterizing Behavioral Effects of Early-Life Stress in an Animal Model of Auditory Processing
普遍的言语节奏规律：语调单元形成低频节奏，并平衡跨语言的音节率变异性。	Inbar, M.	PDF	N/A	A universal of speech timing: Intonation units form low frequency rhythms and balance cross-linguistic syllable rate variability
平等群体中的社会补丁觅食理论	Blum Moyse, L.	PDF	N/A	Social patch foraging theory in an egalitarian group
基于基因共表达网络的间充质干细胞分析揭示了异位骨化的关键基因和分子通路	Yang, M.	PDF	N/A	A gene co-expression network-based analysis of mesenchymal stromal cells reveals novel genes and molecular pathways underlying heterotopic ossification
在津巴布韦利用替代传粉者提高生物多样性和小农户收入	Allebone-Webb, S.	PDF	N/A	Farming with Alternative Pollinators for Increased Biodiversity and Smallholder Incomes in Zimbabwe
最佳实践质量光度法：单分子质量测量的优化指南	Kratochvil, J.	PDF	N/A	Best practice mass photometry: A guide to optimal single molecule mass measurement
植物对特定环境条件的电生理反应	Wilkening, S. H. P.	PDF	N/A	Plant electrophysiological reactions to specific environmental conditions
组蛋白H3.3中单个氨基酸突变揭示了H3K4甲基化在植物中的功能意义	Xue, M.	PDF	N/A	Single amino acid mutations in histone H3.3 illuminate the functional significance of H3K4 methylation in plants
比较早熟、高产及育种潜力方面的籽粒类型和菜用大豆性状	Saha, M.	PDF	N/A	Comparing grain type and vegetable soybean traits for early maturity, higher yield, and breeding potential
比较谷物类型和蔬菜大豆的早熟性、高产性和育种潜力	Saha, M.	PDF	N/A	Comparing grain type and vegetable soybean traits for early maturity, higher yield, and breeding potential
面向AI抗干扰的核酸合成订单筛查：流程、结果与建议	Wittmann, B. J.	PDF	N/A	Toward AI-Resilient Screening of Nucleic Acid Synthesis Orders: Process, Results, and Recommendations
使用tACS对α和β频率神经节律进行研究，探讨其对相位对齐的TMS诱发的皮层脊髓兴奋性的影响	Gialopsou, A.	PDF	N/A	An investigation of the effects of α and β-frequency neural entrainment using tACS on phase-aligned TMS-evoked corticospinal excitability
Anapc5和Anapc7作为KIF18A功能在生育力和有丝分裂进程中的遗传修饰因子	Nesbit, C.	PDF	N/A	Anapc5 and Anapc7 as genetic modifiers of KIF18A function in fertility and mitotic progression
探索线粒体-核相互作用在调控细胞生理中的作用：来自种间细胞质杂种的启示	Gaertner, K.	PDF	N/A	Exploring mitonuclear interactions in the regulation of cell physiology: insights from interspecies cybrids
小胶质细胞经历趋化因子受体CX3CR1介导的胞外Tau内吞作用。	Chidambaram, H.	PDF	N/A	Microglia undergoes chemokine receptor, CX3CR1-mediated internalization of extracellular Tau
溶酶体功能、应激抵抗和修复受损是由于表达亚历山大病GFAP R239C突变体所致。	Hernandez-Gerez, E.	PDF	N/A	Lysosomal function, resistance to stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant
通过E3连接酶TRIM21诱导的化学介导的核孔复合体蛋白降解	LI, X.	PDF	N/A	Chemically Induced Nuclear Pore Complex Protein Degradation via E3 Ligase TRIM21
PHLPP2是一种假磷酸酶，在多细胞生物的祖先中失去了活性。	Husremovic, T.	PDF	N/A	PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor
PHLPP2是一种假磷酸酶，在多细胞生物的祖先中失去了活性。	Husremovic, T.	PDF	N/A	PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor
Pirin 不与 p65 结合，也不调节 NFκB 依赖的基因表达。	Meschkewitz, M.	PDF	N/A	Pirin does not bind to p65 or regulate NFkappaB-dependent gene expression
mRNArchitect：mRNA序列的优化设计	Budzinska, M. A.	PDF	N/A	mRNArchitect: optimized design of mRNA sequences
力场参数、实验测量与分子动力学模拟的综合数据库	Banas, P.	PDF	N/A	Integrated Database of Force-Field Parameters, Experimental Measurements and Molecular Dynamics Simulations
一种计算进化发育生物学方法，用于阐明PLETHORA转录因子在调控根系发育中的作用	Rodriguez-Herrera, J.	PDF	N/A	A computational Evo-Devo approach for elucidating the roles of PLETHORA transcription factors in regulating root development
MpANT-生长素环调节地钱发育	Dipp-Alvarez, M.	PDF	N/A	The MpANT-auxin loop modulates Marchantia polymorpha development
组蛋白H2A及其变体H2A.Z和H2A.W在拟南芥中的结构与功能相互关系	Wang, Y.	PDF	N/A	Structural and functional interrelationship of histone H2A and its variants H2A.Z and H2A.W in Arabidopsis
在拟南芥中，细胞质中的光呼吸乙醛酸旁路在高光条件下支持光合作用和植物生长。	Jiang, X.	PDF	N/A	A photorespiratory glyoxylate shunt in the cytosol supports photosynthesis and plant growth under high light conditions in Arabidopsis
驯化是否以牺牲耐压性为代价来促进叶片生长？对八个早熟禾亚科草种的证据进行搜索	Yun, J.	PDF	N/A	Does domestication trade-off stress tolerance for leaf growth? A search for evidence across eight Pooideae grass species
一种与RdDM相关的雌性特异性元件指导水稻配子体发育过程中的从头DNA甲基化	Kim, T.	PDF	N/A	A female-specific RdDM-associated element guides de novo DNA methylation during rice gametophyte development
分泌途径运输维持拟南芥减数分裂期间纺锤体分离的细胞器带	JIANG, H.	PDF	N/A	Secretory trafficking maintains the organelle band for spindle separation during Arabidopsis meiosis
分泌运输在拟南芥减数分裂期间维持着丝粒分离的细胞器带。	Piskorz, E. W.	PDF	N/A	Secretory trafficking maintains the organelle band for spindle separation during Arabidopsis meiosis
多核巨细胞是卵巢衰老的标志，具有独特的免疫和降解相关分子特征。	Converse, A.	PDF	N/A	Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures
多核巨细胞是卵巢衰老的标志，具有独特的免疫和降解相关分子特征。	Converse, A.	PDF	N/A	Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures
Tmbim5 缺失导致斑马鱼肌肉萎缩，但不会加剧 mcu 或 slc8b1 敲除的表型	Wasilewska, I.	PDF	N/A	Tmbim5 loss causes muscle atrophy in zebrafish without exacerbating mcu or slc8b1 knockout phenotypes
通过高内涵成像在人类破骨细胞中鉴定抗吸收GPCR	Price, M. L.	PDF	N/A	Identification of anti-resorptive GPCRs by high-content imaging in human osteoclasts
利用集成明场和荧光显微镜的组织学引导单细胞质谱成像	Potthoff, A.	PDF	N/A	Histology-Guided Single-Cell Mass Spectrometry Imaging using Integrated Bright-field and Fluorescence Microscopy
利用分离信息进行变异过滤可提高向日葵（Helianthus annuus L.）花蜜生产基因的定位	Barstow, A. C.	PDF	N/A	Variant filters using segregation information improve mapping of nectar-production genes in sunflower (Helianthus annuus L.)
常见的菌根网络介导的植物间信号能够调节植物对生物胁迫的响应以及对叶部病原体的防御	Orlovskis, Z.	PDF	N/A	Common mycelial network mediated inter-plant signals modulate plant biotic stress responses and defence against foliar pathogens
指纹图谱和化学型分析方法揭示了野生啤酒花（Humulus lupulus L.）之间广泛的遗传和代谢多样性。	Ducrocq, F.	PDF	N/A	Fingerprinting and chemotyping approaches reveal a wide genetic and metabolic diversity among wild hops (Humulus lupulus L.)
一种综合方法用于分析蝙蝠对人类病原体的抗体反应	Toshkova, N.	PDF	N/A	An integrative approach for profiling antibody responses in bats to human pathogens
纤毛门锥虫属布鲁氏锥虫中Sec13同源基因的多功能作用	Sharif, M.	PDF	N/A	Multifunctional Roles of Sec13 Paralogues in the Euglenozoan Trypanosoma brucei
α-突触核蛋白纤维的结构多态性改变了Hsc70介导的解聚途径	Jager, S.	PDF	N/A	Structural polymorphism of alpha-synuclein fibrils alters pathway of Hsc70 mediated disaggregation
α-突触核蛋白纤维的结构多态性改变了Hsc70介导的解聚途径	Jager, S.	PDF	N/A	Structural polymorphism of alpha-synuclein fibrils alters pathway of Hsc70 mediated disaggregation
α-突触核蛋白纤维的结构多态性改变了Hsc70介导的解聚途径	Jaeger, S.	PDF	N/A	Structural polymorphism of alpha-synuclein fibrils alters pathway of Hsc70 mediated disaggregation
基于CBAM-ResNet34的温室草莓发育过程分类与评估方法	Wang, J.	PDF	N/A	CBAM-ResNet34-based classification and evaluation method for developmental processes of greenhouse strawberries
霉菌生长和户外暴露对肯尼亚西部诱人目标糖饵效力的影响。	Yalla, n. O.	PDF	N/A	Influence of mould growth and outdoor exposure on the efficacy of attractive targeted sugar baits in western kenya.
短暂光刺激小鼠手部引发的皮层动力学：手/前肢S1和M1区的反应	Pina Novo, D.	PDF	N/A	Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouses hand
Galectin-9与树突状细胞中的HLA-DR结合，调控免疫突触的形成和T细胞的增殖。	Rodgers Furones, A.	PDF	N/A	Galectin-9 binding to HLA-DR in dendritic cells controls immune synapse formation and T cell proliferation
疫苗接种和感染会引发两种不同的人类长期记忆B细胞群体。	Perugino, C.	PDF	N/A	Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection
哺乳动物的SKI复合体是一种广谱抗病毒药物靶点，它通过上调细胞胆固醇水平来抑制病毒复制。	Weston, S.	PDF	N/A	The mammalian SKI complex is a broad-spectrum antiviral drug target that upregulates cellular cholesterol to inhibit viral replication
解析毛癣菌属（Trichophyton mentagrophytes）复合体内的系统发育关系：基于RADseq基因组的方法对“特比萘芬耐药”的Trichophyton indotineae作为独立物种的地位提出质疑	Svarcova, M.	PDF	N/A	Resolving phylogenetic relationships within the Trichophyton mentagrophytes complex: a RADseq genomic approach challenges status of "terbinafine-resistant" Trichophyton indotineae as distinct species
硫磺岛高二氧化碳海洋环境中珊瑚礁共生体群落的变迁	Huerlimann, R.	PDF	N/A	Shifts in Coral Reef Holobiont Communities in the High-CO2 Marine Environment of Iotorishima Island
睫状体尖端中心粒的结构揭示了微管接缝结合蛋白SPEF1的独特作用	Legal, T.	PDF	N/A	Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1
VEXAS贫血是一种镶嵌性红细胞生成减少症。	Rodrigues, F.	PDF	N/A	VEXAS anemia is a mosaic erythroblastopenia
面向光谱变异分析：非目标方法的数据质量框架	Nichani, K.	PDF	N/A	Towards Spectral Variation Analysis: A Data Quality Framework for Non-Targeted Methods
对来自异质性患者来源的GBM干细胞模型进行全面的药理学调查	Elliott, R. J.	PDF	N/A	A comprehensive pharmacological survey across heterogeneous patient-derived GBM stem cell models
依赖于己糖激酶1的植物非生物胁迫免疫取决于叶绿体定位	Bagshaw, S. B.	PDF	N/A	Hexokinase 1-mediated plant immunity under abiotic stress depends on chloroplast positioning
CrGEF1、CrGAP1 和 CrGDI2 作为调节 ROP-GTPase 介导的长春花中生物碱生物合成调控的关键因子。	Sharma, A.	PDF	N/A	CrGEF1, CrGAP1, and CrGDI2 function as key regulators of ROP-GTPase mediated modulation of alkaloid biosynthesis in Catharanthus roseus
产品中立性功能定义的基因相互作用源于细胞生长机制模型。	Fuentes Valenzuela, L.	PDF	N/A	The Product neutrality function defining genetic interactions emerges from mechanistic models of cell growth
ALDH3A1介导的活性醛类解毒作用对去神经化与肌萎缩侧索硬化症进展中的不同肌肉反应有贡献	Li, A.	PDF	N/A	ALDH3A1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to denervation and Amyotrophic Lateral Sclerosis progression
跨越上皮-间质转化（EMT）景观的过渡路径受网络逻辑支配。	Dey, A.	PDF	N/A	Transition paths across the EMT landscape are dictated by network logic
语言网络揭示了由基于域的单词组成的蛋白质句子的语法约束	Shimpi, A. A.	PDF	N/A	Linguistic networks uncover grammatical constraints of protein sentences comprised by domain-based words
受调控的资源再分配在酵母应激反应中是转录上硬连线的	Kocik, R. A.	PDF	N/A	Regulated resource reallocation is transcriptionally hard wired into the yeast stress response
使用单细胞和空间转录组学数据识别替代多聚腺苷酸化工具的指南	Zhao, Q.	PDF	N/A	Guidelines for alternative polyadenylation identification tools using single-cell and spatial transcriptomics data
诱导B细胞受体多样性预测PD-1阻断免疫疗法反应。	Che, Y.	PDF	N/A	Induced B-Cell Receptor Diversity Predicts PD-1 Blockade Immunotherapy Response.
小热休克蛋白1（HSPB1）的协同进化受到α-晶体蛋白结构域与无序区域之间相互作用的促进	Racigh, V.	PDF	N/A	Coevolution in Small Heat Shock Protein 1 (HSPB1) is Promoted by Interactions between the Alpha-Crystallin Domain and the Disordered Regions
双功能变二烯合酶的结构提供了对生物合成二萜装配和环化机制的独特见解。	Wenger, E. S.	PDF	N/A	Structure of Bifunctional Variediene Synthase Yields Unique Insight on Biosynthetic Diterpene Assembly and Cyclization
绘制人类蛋白质组中隐秘磷酸化位点的图谱	Gasparotto, D.	PDF	N/A	Mapping Cryptic Phosphorylation Sites in the Human Proteome
变异刺突蛋白动力学驱动SARS-CoV-2的免疫逃逸	Ugurlu, H.	PDF	N/A	Altered spike dynamics drives immune evasion of SARS-CoV-2
实验性猴痘病毒感染在大鼠中的研究	Rockx, B.	PDF	N/A	Experimental monkeypox virus infection in rats
施马伦贝格病毒的非结构蛋白NSs和NSm对于库蠓属的索诺兰库蠓进行实验性感染并非必需。	Wernike, K.	PDF	N/A	Schmallenberg virus non-structural proteins NSs and NSm are not essential for experimental infection of Culicoides sonorensis biting midges
在C3HeB/FeJ小鼠的隐性新型隐球菌感染过程中，肺部肉芽肿的形成经历了三个免疫学阶段。	Betancourt, J. J.	PDF	N/A	Pulmonary granuloma formation during latent Cryptococcus neoformans infection in C3HeB/FeJ mice involves progression through three immunological phases
在缺乏亲缘识别的情况下，嵌合体的聚集多细胞性	Weltzer, M. L.	PDF	N/A	Chimeric aggregative multicellularity in absence of kin discrimination
HIV-1单个转录起始位点突变体展现出互补的复制功能，这些功能可以通过回复突变得以恢复。	GC, K.	PDF	N/A	HIV-1 single transcription start site mutants display complementary replication functions that are restored by reversion
一种鉴定新生隐球菌敲除文库保真性的方法	Jacobs, E.	PDF	N/A	A method for authenticating the fidelity of Cryptococcus neoformans knockout collections
一种新型白色念珠菌蛋白，受交配信号通路调控，塑造了物种间相互作用	Parnandi, V. A.	PDF	N/A	A novel Candida glabrata protein regulated by mating signaling pathway shapes inter-species interaction
结核分枝杆菌痰液直接测序的方案和产率：系统综述与荟萃分析	Mann, B. C.	PDF	N/A	Systematic review and meta-analysis of protocols and yield of direct from sputum sequencing of Mycobacterium tuberculosis
深度突变扫描（DMS）的CHIKV E3/E2病毒库映射了病毒氨基酸偏好，并预测了中和CHIKV抗体的病毒逃逸突变体。	Stumpf, M. M.	PDF	N/A	Deep mutationally scanned (DMS) CHIKV E3/E2 virus library maps viral amino acid preferences and predicts viral escape mutants of neutralizing CHIKV antibodies
乌苏图病毒非洲3.1系，葡萄牙，2021-2023年	Queiros, J.	PDF	N/A	Usutu virus African 3.1 lineage, Portugal, 2021-2023
在复制压力的进出之间：基于PCNA/RPA1的动态调控同一细胞中的复制叉停滞与重启	Dyankova-Danovska, T. K.	PDF	N/A	In and out of replication stress: PCNA/RPA1-based dynamics of fork stalling and restart in the same cell
高分辨率成像与三维视网膜色素上皮层结构解析	Donaldson, K. J.	PDF	N/A	High resolution imaging and interpretation of three-dimensional RPE sheet structure
PTX3调控成纤维细胞-上皮细胞动力学在肺损伤与修复中的作用	Bammert, M.-T.	PDF	N/A	PTX3 Governs Fibroblast-Epithelial Dynamics in Lung Injury and Repair
高通量发现与深入表征细胞周期蛋白-CDK结合基序	Ord, M.	PDF	N/A	High-throughput discovery and deep characterization of cyclin-CDK docking motifs
PTTG1介导的周细胞功能障碍驱动糖尿病诱导的微血管功能障碍	Zhang, L.	PDF	N/A	PTTG1-Mediated Pericyte Dysfunction Drives Diabetes-Induced Microvascular Dysfunction
在疫情期间，SARS-CoV-2基因组组成异质性呈现出加速下降的系统发育趋势。	Oliver, J. L.	PDF	N/A	An accelerating, decreasing phylogenetic trend in SARS-CoV-2 genome compositional heterogeneity during the pandemic
杂交和基因流对基因共表达网络的影响	Runghen, R.	PDF	N/A	Effects of hybridization and gene flow on gene co-expression networks
广泛存在的基因-环境相互作用塑造了住院COVID-19患者对SARS-CoV-2感染的免疫反应	Randolph, H. E.	PDF	N/A	Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients
癌基因SLC35F2是一种对微量营养素喹啉和喹喔啉具有高特异性的转运体。	Burtnyak, L.	PDF	N/A	The oncogene SLC35F2 is a high-specificity transporter for the micronutrients queuine and queuosine
鉴定针对淋病奈瑟菌丝氨酸乙酰转移酶的新型抑制剂	Oldham, K.	PDF	N/A	Identification of novel inhibitors targeting serine acetyltransferase from Neisseria gonorrhoeae
SMYD2-PARP1复合物的结构揭示了肽结合的生产性和变构性模式	Zhang, Y.	PDF	N/A	Structure of the SMYD2-PARP1 Complex Reveals Both Productive and Allosteric Modes of Peptide Binding
基于瓶子的深度单细胞蛋白质组学一步预处理及其在卵母细胞老化中的应用	Yang, Y.	PDF	N/A	Simple One-step Vial-based Pretreatment for Deep Single-cell Proteomics and Its Application to Oocyte Aging
利用FBXW7体细胞突变型R465C进行靶向蛋白质降解	Basu, A. A.	PDF	N/A	Harnessing the FBXW7 somatic mutant R465C for targeted protein degradation
进化对位置序列、集体性质和原弹性蛋白序列风格施加了限制，这些限制是由形成和功能的基本要求所决定的，这些要求与细胞外弹性基质的形成和功能密切相关。	Keeley, F. W.	PDF	N/A	Evolutionary Constraints on Positional Sequence, Collective Properties and Sequence Style of Tropoelastin Dictated by Fundamental Requirements for Formation and Function of the Extracellular Elastic Matrix
tilvestamab与AXL复合物的结构分析	Christakou, E.	PDF	N/A	Structural analysis of tilvestamab in complex with AXL
结核分枝杆菌感染的肺泡上皮细胞中的同位素示踪表明，其代谢特异性与其毒力和耐药状态相关。	Akram, S.	PDF	N/A	Isotopic tracing in Mycobacterium tuberculosis-infected alveolar epithelial cells indicates metabolic specificity to their virulence and drug-resistance status
通过计算机预测域插入位点实现蛋白质别构开关的合理工程设计	Wolf, B.	PDF	N/A	Rational engineering of allosteric protein switches by in silico prediction of domain insertion sites
BEVA2.0：利用黄金门兼容向量进行模块化组装，扩展遗传工程应用	Geddes, B. A.	PDF	N/A	BEVA2.0: Modular Assembly of Golden Gate-Compatible Vectors with Expanded Utility for Genetic Engineering
HIV-1蛋白编码序列存在于相关细菌中。	Pelaez-Prestel, H. F.	PDF	N/A	HIV-1 protein coding sequences are present in relevant bacteria
一种主要的昆虫寄生虫通过干扰白纹伊蚊传播基孔肯雅病毒。	Martin, E.	PDF	N/A	A major entomoparasite interferes with Chikungunya transmission by Aedes albopictus
隐形眼镜佩戴改变了角膜上皮和细菌对铜绿假单胞菌的转录反应	Kumar, N. G.	PDF	N/A	Contact Lens Wear Alters Transcriptional Responses to Pseudomonas aeruginosa in Both the Corneal Epithelium and the Bacteria
在奶牛场中，与临床相关的稳定蝇和粪便来源的细菌分离物中，抗菌药物抗性表型和基因的流行情况	Sommer, A. J.	PDF	N/A	Prevalence of antimicrobial resistance phenotypes and genes in stable fly- and manure-derived bacterial isolates from clinically relevant taxa in dairy settings
血小板生物能量学与C57BL/6J小鼠骨骼肌代谢相关	Wilkinson, M. S.	PDF	N/A	Platelet bioenergetics correlate with skeletal muscle metabolism in C57BL/6J mice
RNA结合蛋白PRRC2B在饥饿期间保护5' TOP mRNA，以在营养恢复期间维持核糖体生物合成。	Goldberg, N.	PDF	N/A	The RNA-binding protein PRRC2B preserves 5' TOP mRNA during starvation to maintain ribosome biogenesis during nutrient recovery
细胞原型图谱	Crowley, G.	PDF	N/A	An Atlas of Cellular Archetypes
扩展HP1a结合的共识序列和异染色质组装的分子语法	Colmenares, S. U.	PDF	N/A	Expanding the HP1a-binding consensus and molecular grammar for heterochromatin assembly
D1是一种新型增强子阻断蛋白，其功能通过多个富含AT的简单序列重复实现。	Kundurthi, P.	PDF	N/A	D1 is a novel enhancer blocker protein that functions via multiple AT-rich simple sequence repeats
谱系特异性氨基酸定义了Rad51和Dmc1重组酶单体-单体界面的功能属性	Petassi, M.	PDF	N/A	Lineage-specific amino acids define functional attributes of the protomer-protomer interfaces for the Rad51 and Dmc1 recombinases
CRISPR/AAV介导的精确基因组编辑在心脏应用	Zheng, Y.	PDF	N/A	Cardiac Applications of CRISPR/AAV-Mediated Precise Genome Editing
皮肤元转录组学揭示了微生物活动和基因表达在整个人体中的变异景观	Chia, M.	PDF	N/A	Skin metatranscriptomics reveals landscape of variation in microbial activity and gene expression across the human body
PITHD1：细胞休眠期间26S蛋白酶体的内源性抑制剂	Amann, S. J.	PDF	N/A	PITHD1: An Endogenous Inhibitor of the 26S Proteasome During Cellular Dormancy
多组学分析苜蓿和小麦诱发西藏绵羊瘤胃胀气的机制	Zhao, W.	PDF	N/A	Multi-omics analysis of the mechanism of alfalfa and wheat-induced rumen flatulence in Xizang sheep
色素上皮衍生因子缺失使C57BL/6J小鼠对光诱导的视网膜损伤敏感	Shelton, D. A.	PDF	N/A	Loss of Pigment Epithelium Derived Factor Sensitizes C57BL/6J Mice to Light-Induced Retinal Damage
一种预测单细胞蛋白质组学特性的算法	Arroyo, J. I.	PDF	N/A	An algorithm for predicting per-cell proteomic properties
掌握曼努之技 - 人类如何制造巨大水花	Rohilla, P.	PDF	N/A	Mastering the Manu - How humans create large splashes
口服烟酰胺核糖补充剂在DBA/2J小鼠模型中保护视网膜神经节细胞	Zhang, N.	PDF	N/A	Oral supplementation with Nicotinamide Riboside treatment protects RGCs in DBA/2J mouse model
由植物乳杆菌SJ33产生的新型低分子量化合物对肺炎克雷伯菌的抗生物膜活性	Ray Mohapatra, A.	PDF	N/A	Anti-biofilm activity of new low molecular weight compounds produced by Lactiplantibacillus plantarum SJ33 against Klebsiella pneumoniae
人类干细胞衍生的GABA能中间神经元发育揭示了早期亚型多样性的出现，随后是逐渐的电化学成熟过程。	Bershteyn, M.	PDF	N/A	Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity followed by gradual electrochemical maturation
揭示人类大脑活动中的节奏分类	Barbero, F. M.	PDF	N/A	Revealing rhythm categorization in human brain activity
自恋型和反社会型人格特质均编码于三重网络中：连接组学证据	Jornkokgoud, K.	PDF	N/A	Narcissistic and Antisocial Personality Traits are both encoded in the Triple Network: Connectomics evidence
单细胞全长异构体测序揭示了在脑皮质发育过程中自闭症谱系障碍的转录失调	Xu, X.	PDF	N/A	Single-Cell full-length Isoform Sequencing Unveils Transcriptional Dysregulation in Autism Spectrum Disorder During Cerebral Cortex Development
在羊膜动物中，半球间形态发生的保守性先于胼胝体（corpus callosum）的进化。	Noji, R.	PDF	N/A	Conserved interhemispheric morphogenesis in amniotes preceded the evolution of the corpus callosum
组蛋白去甲基化酶KDM5在大脑中具有绝缘活性	Yheskel, M.	PDF	N/A	The histone demethylase KDM5 has insulator activity in the brain
鸟类端脑和小脑的体积可以通过数字脑内模准确估算。	Keirnan, A. R.	PDF	N/A	Avian telencephalon and cerebellum volumes can be accurately estimated from digital brain endocasts
背内侧纹状体的胆碱能中间神经元介导雄性小鼠社交层级动态中的胜者-败者效应。	Hsu, M.-T.	PDF	N/A	Cholinergic interneurons of the dorsomedial striatum mediate winner-loser effects on social hierarchy dynamics in male mice.
在脑发育过程中，小胶质细胞中的组织蛋白酶B促进神经元的吞噬作用。	Silva, N. J.	PDF	N/A	Microglial cathepsin B promotes neuronal efferocytosis during brain development
早期生活压力会损害活体前额叶-杏仁核网络内功能性相互作用和神经活动的发育	Donati, A.	PDF	N/A	Early-life stress impairs development of functional interactions and neuronal activity within prefrontal-amygdala networks in vivo
# BioRxiv 2024-12-03 Papers

标题	作者	PDF链接	代码仓库	Title
不太本地化：玉米和类蜀黍趋同适应的群体遗传学。	Tittes, S.	PDF	N/A	Not so local: the population genetics of convergent adaptation in maize and teosinte.
果蝇个体气味偏好的神经相关性	Churgin, M.	PDF	N/A	A neural correlate of individual odor preference in Drosophila
在小鼠发育中的大脑皮层中，急性产前酒精暴露后DNA甲基化和转录组的即时扰动	DUCHATEAU, A.	PDF	N/A	Immediate perturbation of DNA methylation and transcriptome upon acute prenatal alcohol exposure in the mouse developing brain cortex
雌性北棕林鸫（Troglodytes aedon）在对抗三种模拟捕食者时的风险评估	Eggleston, R. C.	PDF	N/A	Risk assessment during nest defense against three simulated predators by female northern house wrens (Troglodytes aedon)
xTrimoPGLM：统一100亿规模预训练变压器，用于解读蛋白质语言	Chen, B.	PDF	N/A	xTrimoPGLM: Unified 100B-Scale Pre-trained Transformer for Deciphering the Language of Protein
通过果蝇模型识别心血管疾病与失眠之间的新关联，该模型基于一个多效性全基因组关联研究位点的基因	Abou Daya, F.	PDF	N/A	Identifying novel links between cardiovascular disease and insomnia by Drosophila modeling of genes from a pleiotropic GWAS locus
抑制NINJ1依赖的质膜破裂可防止炎症小体诱导的血液凝固和炎症	Wu, C.	PDF	N/A	Inhibiting NINJ1-dependent plasma membrane rupture protects against inflammasomeinduced blood coagulation and inflammation
常染色体显性多囊肾病（ADPKD）是由多囊蛋白-1（Polycystin-1）中的错义变异引起的，这些变异破坏了细胞表面定位或多囊蛋白通道功能。	Ha, K.	PDF	N/A	ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function
视觉和触觉持续时间再现中的准确性反馈和延迟适应效应	Chen, L.	PDF	N/A	Accuracy Feedback and Delay Adaptation Effects in Visual and Tactile Duration Reproduction
通过体内注射和电穿孔裸露mRNA恢复患有少弱畸精子症小鼠的精子生育力	Vilpreux, C.	PDF	N/A	Sperm fertility restoration in mice suffering from oligo-astheno-teratozoospermia by in vivo injection and electroporation of naked mRNA
DNA甲基组调控丁香假单胞菌的毒力和代谢	Huang, J.	PDF	N/A	DNA Methylome Regulates Virulence and Metabolism in Pseudomonas syringae
真菌蛋白Jps1通过直接的磷脂酰肌醇相互作用促进非常规蛋白质分泌。	Dali, S.	PDF	N/A	The fungal protein Jps1 facilitates unconventional protein secretion through a direct phosphoinositide interaction
细胞周期和年龄相关的小鼠染色体刚性调节	Liu, N.	PDF	N/A	Cell-cycle and Age-Related Modulations in Mouse Chromosome Stiffness
果蝇科温度偏好行为的演变	Kafle, T.	PDF	N/A	Evolution of temperature preference behaviour among drosophilids
基于宏转录组学的感染期间患者特异性尿液微生物组的代谢建模	Josephs-Spaulding, J.	PDF	N/A	Metatranscriptomics-based metabolic modeling of patient-specific urinary microbiome during infection
自然行为中视觉运动协调的低维表示	Keshava, A.	PDF	N/A	Low-Dimensional Representations of Visuomotor Coordination for Natural Behavior
一种可调且多功能的近红外荧光化学遗传报告器	El Hajji, L.	PDF	N/A	A tunable and versatile chemogenetic near infrared fluorescent reporter
行走的果蝇中运动统计的抑制性控制	Gattuso, H.	PDF	N/A	Inhibitory control of locomotor statistics in walking Drosophila
一种多状态捕获-重捕模型，用于估计北大西洋露脊鲸的繁殖情况。	Linden, D. W.	PDF	N/A	A multistate capture-recapture model to estimate reproduction of North Atlantic right whales
基于能量的适应性免疫 repertoire 行为系统建模：细胞增殖与体细胞超突变过程研究	Chen, Y.	PDF	N/A	Energy-Based Systematic Modeling of Adaptive Immune Repertoire Behavior: Study on Cell Proliferation & Somatic Hypermutation process
Q175亨廷顿病模型小鼠中mTOR抑制促进神经元自噬及突变亨廷顿蛋白清除	Stavrides, P.	PDF	N/A	mTOR inhibition in Q175 Huntington's disease model mice facilitates neuronal autophagy and mutant huntingtin clearance
斑马鱼肠道中的蛋白质吸收受到富含溶酶体的肠细胞与微生物群之间相互作用的调控。	Childers, L.	PDF	N/A	Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome
分流细胞的瞬态和动态特性源自其行为。	Chaix-Echel, N.	PDF	N/A	The transient and dynamic nature of splitter cells derive from behavior
结构变异对玉米表型变异有贡献	Catlin, N. S.	PDF	N/A	Structural variants contribute to phenotypic variation in maize
在不增加训练或数据的情况下提高逆折叠模型在蛋白质稳定性预测中的表现	Dutton, O.	PDF	N/A	Improving Inverse Folding models at Protein Stability Prediction without additional Training or Data
利用时间维度和光谱维度实现多样性热带森林中的综合单木树种制图	Ball, J. G. C.	PDF	N/A	Towards comprehensive individual tree species mapping in diverse tropical forests by harnessing temporal and spectral dimensions
细胞拥挤会诱导TRPV4的抑制及其向质膜的重新定位，暗示了促进侵袭的细胞体积减少机械转导途径。	Bu, X.	PDF	N/A	Cell crowding induces TRPV4 inhibition and its relocation to plasma membranes, implicating pro-invasive cell volume reduction mechanotransduction pathway
利用动力学信息提高基因组规模代谢模型的准确性	Lazaro Ibanez, J.	PDF	N/A	Enhancing the accuracy of genome-scale metabolic models with kinetic information
错位视网膜轴突在白化小鼠的视觉丘脑中诱导出一种突触独立的子回路。	McCracken, S.	PDF	N/A	Mistargeted retinal axons induce a synaptically independent subcircuit in the visual thalamus of albino mice.
两个相互作用细胞之间对齐机制的动力学分析	Leech, V.	PDF	N/A	A dynamical analysis of the alignment mechanism between two interacting cells
基于结构的RyR通道操作机制：钙离子和镁离子的作用	Zahradnikova, A.	PDF	N/A	Structure-based mechanism of RyR channel operation by calcium and magnesium ions
基因组数据显示，非洲各地的血吸虫（Schistosoma haematobium）种群存在南北分化及基因渐渗历史。	Platt, R. N.	PDF	N/A	Genomic data reveal a north-south split and introgression history of blood fluke (Schistosoma haematobium) populations from across Africa
解决功能神经影像学中的不一致性：一种可复制的、数据驱动的多尺度功能图谱，用于标准脑网络	Jensen, K. M.	PDF	N/A	Addressing inconsistency in functional neuroimaging: A replicable data-driven multi-scale functional atlas for canonical brain networks
一种综合方法，用于提取经历液-液相分离的球状蛋白质的旋转动力学	Gendreizig, D.	PDF	N/A	A combined approach to extract rotational dynamics of globular proteins undergoing liquid-liquid phase separation
纤维化中异位肺泡基底细胞相对于气道基底细胞的特征	Blumer, S.	PDF	N/A	Characteristics of ectopic alveolar basal cells relative to airway basal cells in fibrosis
inPhase - 一种简单、准确且快速的方法来确定蛋白质凝聚相图	Fritsch, A. W.	PDF	N/A	inPhase - A simple, accurate and fast approach to determine phase diagrams of protein condensates
有丝分裂后依赖PP2A-Ankle2的核重构机制	Li, J.	PDF	N/A	Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis
一种肿瘤胚胎学方法揭示了SoxC驱动的结肠发育和癌症调控机制	Dalessi, T.	PDF	N/A	An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer
淀粉样前体蛋白（Amyloid Beta Precursor Protein）有助于短命的绿松石鳉鱼（Nothobranchius furzeri）的脑老化和学习能力下降。	de Bakker, D. E. M.	PDF	N/A	Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)
由祖先SARS-CoV-2印记的B细胞在免疫回忆中产生广谱的沙贝病毒中和能力	Chen, X.	PDF	N/A	B cells imprinted by ancestral SARS-CoV-2 develop pan-sarbecovirus neutralization in immune recalls
TreeFormer：一种基于Transformer的树重排操作，用于系统发育重建	Ly-Trong, N.	PDF	N/A	TreeFormer: A transformer-based tree rearrangement operation for phylogenetic reconstruction
基于片段的小分子抑制剂开发，靶向结核分枝杆菌胆固醇代谢	Kavanagh, M. E.	PDF	N/A	Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism
ERP和神经振荡能否用于在一个生态有效的运动模型中区分熟练和非熟练玩家的表现？	Winstanley, M.	PDF	N/A	Can ERPs and neural oscillations be used to differentiate skilled and unskilled player performance in an ecologically valid sporting model?
药物的环境影响：对近期关于水生浓度及可预测效应数据的证据映射回顾	Renda, F.	PDF	N/A	The environmental impact of pharmaceuticals: an evidence-mapping review of recent data on aquatic concentrations and predictable effects
甲型流感病毒的转录产生加帽的cRNA，这些cRNA能够激活RIG-I。	Elshina, E.	PDF	N/A	Influenza A virus transcription generates capped cRNAs that activate RIG-I
一种简单的新替代线性-二次模型（以及LQ模型的来源）	Bilinsky, L.	PDF	N/A	A simple new alternative to the linear-quadratic model (and where the LQ model comes from)
对Diversity Outbred小鼠研究中寿命的分析确定了多个与长寿相关的位点	Mullis, M. N.	PDF	N/A	Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci
原位整合多孔聚乙烯纳米膜与伤口渗出液以实现无痕愈合	Yuan, S.	PDF	N/A	In Situ Integration of Porous Polyethylene Nanomembrane with Wound Exudates for Scarless Healing
高分辨率分析揭示了转基因的转录和翻译调控的耦合关系	Peterman, E. L.	PDF	N/A	High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes
广泛存在的肠杆菌过氧化物酶封装体的结构和生化特性	Ubilla-Rodriguez, N. C.	PDF	N/A	Structural and biochemical characterization of a widespread enterobacterial peroxidase encapsulin
对动力蛋白-动力蛋白激活蛋白-NuMA复合物的激活和调控的结构与功能解析	Aslan, M.	PDF	N/A	Structural and functional insights into activation and regulation of the dynein-dynactin-NuMA complex
过度活跃的神经网络促进阿尔茨海默病小鼠模型中的tau蛋白扩散	Barbour, A. J.	PDF	N/A	Hyperactive neuronal networks facilitate tau spread in an Alzheimer's disease mouse model
果蝇对细菌肽聚糖的感知反应整合了正向和负向信号	Montanari, M.	PDF	N/A	Drosophila's sensory responses to bacterial peptidoglycan integrates positive and negative signals
哺乳动物增强子和全基因组关联研究（GWASs）主要在基因附近发挥作用，很少跨越活跃基因。	Choudhary, C.	PDF	N/A	Mammalian enhancers and GWASs act proximally and seldom skip active genes
玉米裸粒的古老起源	Fairbanks, R. A.	PDF	N/A	An ancient origin of the naked grains of maize
玉米及相关物种中生殖屏障的分子进化	Cryan, E.	PDF	N/A	Molecular evolution of a reproductive barrier in maize and related species
根癌农杆菌A4衍生菌株在烟草和其它茄科植物中实现超高效瞬时基因表达	Lopez-Agudelo, J. C.	PDF	N/A	Rhizobium rhizogenes A4-derived strains mediate hyper-efficient transient gene expression in Nicotiana benthamiana and other solanaceous plants
机械应力引导气孔分裂，形成组织尺度的排列。	Serra, L.	PDF	N/A	Mechanical stress orients stomata division to form tissue scale alignments.
番茄疫霉病潜在生物防治剂的时空化学研究	Robinson, J. Y.	PDF	N/A	Spatiochemical Investigation of Potential Biocontrol Agents Against Phytophthora capsici Infection in Tomato
由亚麻锈病菌Melampsora lini介导的效应蛋白向植物细胞的转运	Zhang, X.	PDF	N/A	Translocation of effector proteins into plant cells by the flax rust pathogen Melampsora lini
通过宿主到群体的计算机病毒进化，利用深度学习实现生成式流行突变预测	Liu, X.	PDF	N/A	Deep-learning-enabled generative prevalent mutation prediction through host-to-herd in silico virus evolution
MAAPE：一种模块化蛋白质嵌入进化分析方法	Wang, X.	PDF	N/A	MAAPE: A Modular Approach to Evolutionary Analysis of Protein Embeddings
昆虫对植物挥发性物质的气相色谱-耦合电位图检测（GC-EAD）的定量分析	Byers, K. J. R. P.	PDF	N/A	Quantitative analysis of gas chromatography-coupled electroantennographic detection (GC-EAD) of plant volatiles by insects
植物机械应答中细胞骨架和质体骨架蛋白的功能、生物素化蛋白质组学和生物信息学分析	WU, K.	PDF	N/A	Functional, Biotinylproteomic and Bioinformatic Analysis of Both Cytoskeletal and Plastoskeletal Proteins in Plant Mechanoresponse
保守效应因子支撑了从苔藓中分离出的假单胞菌在不同植物中的致病性	Robinson, K.	PDF	N/A	Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants
性别偏倚基因表达在性对抗选择和性限制选择下的表现	Wiberg, R. A. W.	PDF	N/A	Sex-biased gene expression under sexually antagonistic and sex-limited selection
可解释人工智能引导的植物中选择性siRNA积累的新型蛋白质-RNA相互作用框架的鉴定	Enoki, N.	PDF	N/A	Explainable AI-guided identification of a novel protein-RNA interactive frame for selective siRNA accumulation in plants
生成式人工智能的分化：大学生背景如何影响其生成式AI素养	Jiang, J.	PDF	N/A	Generative AI divide: How College Students' Backgrounds Affect Their Gen AI Literacy
TET敲除细胞在多能态之间转换，并表现出过早的生殖系进入。	Chambers, I.	PDF	N/A	TET knockout cells transit between pluripotent states and exhibit precocious germline entry
性二态性与间性关联：模型是否支持直觉？	Puixeu, G.	PDF	N/A	The relationship between sexual dimorphism and intersex correlation: do models support intuition?
解开适应性与非适应性过程在Coenonympha蝴蝶生殖隔离进化中的贡献。	Capblancq, T.	PDF	N/A	Untangling the contribution of adaptive versus non-adaptive processes in the evolution of reproductive isolation between Coenonympha butterflies.
数字DNA系统揭示了单向遗传相对于“拉马克式”遗传的优越性	Shiju, A.	PDF	N/A	A digital DNA system reveals the superiority of unidirectional inheritance over 'Lamarckian' inheritance
通过mitology R包解析转录组数据中的线粒体活性	Pirrotta, S.	PDF	N/A	Dissect mitochondrial activity by transcriptome data with mitology R package
人类糖皮质激素受体变异体rs6190促进血液胆固醇水平和动脉粥样硬化的发生。	Durumutla, H. B.	PDF	N/A	The human glucocorticoid receptor variant rs6190 promotes blood cholesterol and atherosclerosis
雌激素信号在Reprimo谱系细胞中的性别特异性体温调节作用	Park, J. W.	PDF	N/A	Sex-specific thermoregulatory effects of estrogen signaling in Reprimo lineage cells
光量影响拟南芥幼叶对寒冷的早期反应和冷适应	Luklova, M.	PDF	N/A	Light quantity impacts early response to cold and cold acclimation in young leaves of Arabidopsis
拟南芥花粉管向性调控因子PCP-B与RALF23/33竞争结合的结构基础	Bhalla, H.	PDF	N/A	Structural Insights into Competitive Binding Dynamics between RALF23/33 and PCP-B in Brassicaceae Pollination
单核测序揭示了Moricandia arvensis中束鞘细胞在C3-C4中间型十字花科植物光呼吸穿梭中的功能	Triesch, S.	PDF	N/A	Single-nuclei sequencing of Moricandia arvensis reveals bundle sheath cell function in the photorespiratory shuttle of C3-C4 intermediate Brassicaceae
从头设计的pMHC结合剂促进T细胞介导的癌细胞杀伤	Johansen, K. H.	PDF	N/A	De novo designed pMHC binders facilitate T cell induced killing of cancer cells
一个评分统治所有：基于GWAS汇总统计的正则化集成多基因风险预测	Zhao, Z.	PDF	N/A	One score to rule them all: regularized ensemble polygenic risk prediction with GWAS summary statistics
犬持续性苗勒管综合征：对AMH和AMHR2基因组织的新见解	Krzeminska, P.	PDF	N/A	Persistent Mullerian duct syndrome in dogs: a new insight into organization of AMH and AMHR2 genes
移植后间充质细胞的单细胞多组学分析揭示了肺纤维化的分子特征及潜在调控因子	Lu, L.	PDF	N/A	Single-cell multi-omic analysis of post-transplant mesenchymal cells reveals molecular signatures and putative regulators of lung fibrosis
移植后间充质细胞的单细胞多组学分析揭示了肺纤维化的分子特征及潜在调控因子	Lu, L.	PDF	N/A	Single-cell multi-omic analysis of post-transplant mesenchymal cells reveals molecular signatures and putative regulators of lung fibrosis
中性粒细胞在实验性牙周炎中驱动性别二态性	Martin, K.	PDF	N/A	Neutrophils drive sexual dimorphism in experimental periodontitis
环境毒素衍生的α-突触核蛋白对肠神经-上皮相互作用的性别特异性影响	Templeton, H. N.	PDF	N/A	Sex specific effects of environmental toxin-derived alpha synuclein on enteric neuronal-epithelial interactions
早期接触西方饮食会加剧雌性小鼠的视觉结果。	Meseguer, D.	PDF	N/A	Early exposure to Western diet exacerbates visual outcomes in female mice.
探索类胡萝卜素对致病性尖孢镰刀菌（Fusarium oxysporum f.sp. lini）和内生菌Fo47菌株的影响	Kochneva, Y.	PDF	N/A	Exploring the Impact of Apocarotenoids on Pathogenic Fusarium oxysporum f.sp. lini and Endophytic Fo47 strains
调节APC/C调控因子SlSAMBA的活性可提高番茄果实的糖分和抗氧化物质含量	de Oliveira, P. N.	PDF	N/A	Modulating activity of the APC/C regulator SlSAMBA improves the sugar and antioxidant content of tomato fruits
去除表皮蜡质对角质层蜡质沉积速率没有影响，成熟桂樱叶的角质层蜡质沉积速率是恒定的。	Janova, J.	PDF	N/A	Removal of epicuticular wax has no effect on the rate of cuticular wax deposition, which is constant in mature cherry laurel leaves
多功能的IL-21+ IFNg+ T滤泡辅助细胞有助于检查点抑制剂糖尿病的发生，并可通过JAK抑制剂疗法进行靶向治疗。	Huang, N.	PDF	N/A	Polyfunctional IL-21+ IFNg+ T follicular helper cells contribute to checkpoint inhibitor diabetes mellitus and can be targeted by JAK inhibitor therapy
改进人工智能与现有生态推断工作流程的整合	Cowans, A.	PDF	N/A	Improving the integration of AI into existing ecological inference workflows
伊朗希尔卡尼亚森林中丛林猫的车辆碰撞风险建模：车辆碰撞预防指南	Ashoori, A.	PDF	N/A	Modeling vehicle collision risk for the jungle cat in the Hyrcanian forests of Iran: A guide for vehicle collision prevention
量化单细胞数据中的病理进展	Khan, S. R.	PDF	N/A	Quantifying Pathological Progression from Single-Cell Data
C2AM-Unet：用于视网膜血管分割的坐标与通道注意力混合灵活架构	Zhang, J.	PDF	N/A	C2AM-Unet: Coordinate and Channel Attention Mixing Flexible Architecture for Retinal Vessel Segmentation
亚马逊药用植物中潜在的抗病毒和免疫调节化合物	Napoleao, S. M. d. S.	PDF	N/A	Potential antiviral and immunomodulatory Amazonian medicinal plant compounds
结构趋同和水介导的底物模拟使人类抗体能够广泛抑制神经氨酸酶	Lederhofer, J.	PDF	N/A	Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies
健康人体免疫系统和微生物群的协调变化与持续性干扰素状态有关。	Babdor, J.	PDF	N/A	Coordinated variation in the immune systems and microbiomes of healthy humans is linked to tonic interferon states
单细胞基因表达的动力学模式可区分小鼠对减毒活疫苗和灭活黄热病疫苗的细胞反应	Chatterjee, B.	PDF	N/A	Kinetic patterns of single cell gene expression discriminate between the murine cellular responses to live attenuated and inactivated Yellow Fever vaccines
从公民科学和深度学习对珊瑚礁进行大规模勘察	Lawson, C. L.	PDF	N/A	Broadscale reconnaissance of coral reefs from citizen science and deep learning
波卡：一只负载比高达6847%的死灵机器人甲虫	Tsvetkov, Y.	PDF	N/A	Poka: a necro-robot beetle with a measured payload ratio of 6847%
核苷酸GPT：基于序列的深度学习预测核亚区室相关基因组结构	Mclaughlin, S. M.	PDF	N/A	Nucleotide GPT: Sequence-Based Deep Learning Prediction of Nuclear Subcompartment-Associated Genome Architecture
重塑乳腺癌肝转移局部治疗格局：一种新型瘤内p21靶向经皮疗法可提高BALB/c小鼠接种4T1三阴性乳腺癌细胞后的生存率。	Margulies, B. S.	PDF	N/A	Reshaping the Landscape of Locoregional Treatments for Breast Cancer Liver Metastases: A novel, intratumoral, p21-targeted percutaneous therapy increases survival in BALB/c mice inoculated with 4T1 triple negative breast cancer cells in the liver.
TLR7/8激动剂INI-4001增强了Powassan病毒样颗粒疫苗的免疫原性。	Crawford, M. W.	PDF	N/A	The TLR7/8 agonist INI-4001 enhances the immunogenicity of a Powassan virus-like-particle vaccine
浮游牡蛎幼虫在复杂的感官环境中优化定居决策	Schmidlin, S.	PDF	N/A	Planktonic oyster larvae optimize settlement decisions in complex sensory landscapes
新型Hybprinter-SAM的开发：用于具有图案化和局部生化信号的功能梯度组织工程构建体	Li, J.	PDF	N/A	Development of a Novel Hybprinter-SAM for Functionally Graded Tissue Engineering Constructs with Patterned and Localized Biochemical Signals
体内在线无标记监测光疗过程中异质性氧利用率，实时超声引导光声成像	Langley, A.	PDF	N/A	In vivo Online label-free monitoring of heterogenous oxygen utilization during phototherapy with real-time ultrasound guided photoacoustic imaging
ReSCU-Nets：用于多维显微镜数据分割的递归U-Nets	Hawkins, R.	PDF	N/A	ReSCU-Nets: recurrent U-Nets for segmentation of multidimensional microscopy data
AlphaPulldown2 - 一种用于高通量结构建模的通用流程	Molodenskiy, D.	PDF	N/A	AlphaPulldown2 - A General Pipeline for High-Throughput Structural Modeling
在单细胞和空间组学数据中检测亚群的度量标准	Luo, S.	PDF	N/A	On metrics for subpopulation detection in single-cell and spatial omics data
针对G蛋白偶联受体的特定状态多肽设计	Xue, Y.	PDF	N/A	State-specific Peptide Design Targeting G Protein-coupled Receptors
深度学习方法在RNA三级结构预测中的比较综述	Martinovic, I.	PDF	N/A	A Comparative Review of Deep Learning Methods for RNA Tertiary Structure Prediction
ACE：一种用于单细胞镶嵌整合的多功能对比学习框架	Yan, X.	PDF	N/A	ACE: a versatile contrastive learning framework for single-cell mosaic integration
VBayesMM：用于优先处理高维微生物组多组学数据重要关系的变化贝叶斯神经网络	Dang, T.	PDF	N/A	VBayesMM: Variational Bayesian neural network to prioritize important relationships of high-dimensional microbiome multiomics data
细胞类型特异性表观基因组亚型分类提高了癌症预后分层的准确性。	Luo, Q.	PDF	N/A	Cell-type specific subtyping of epigenomes improves prognostic stratification of cancer
通过内部驱动的定向力实现细胞片层形状转变	Huang, J.	PDF	N/A	Cell-sheet shape transformation by internally-driven, oriented forces
利用大型语言模型解决空间转录组学数据解读的复杂性	Khan, T.	PDF	N/A	Tackling the Complexity of Spatial Transcriptomics Data Interpretation with Large Language Models
通过机械疗法和超声波穿透技术优化实体瘤的治疗效果	Koutsi, M.	PDF	N/A	Optimizing therapeutic outcomes with Mechanotherapy and Ultrasound Sonopermeation in solid tumors
人胰腺肿瘤和小肠微生物群的分离与鉴定	Awad, D.	PDF	N/A	Isolation and characterization of microbiota from human pancreatic tumors and small intestine
推进白细胞检测：形态学分析的多领域数据集及应对稀疏标注挑战	Rehman, A.	PDF	N/A	Advancing White Blood Cell Detection: A Multi-Domain Dataset for Morphological Analysis and Addressing Sparse Annotation Challenges
SS-31可预防博来霉素诱导的肺损伤和纤维化。	Gu, Q.	PDF	N/A	SS-31 protects against bleomycin-induced lung injury and fibrosis
面向营养不良的综合解决方案：新型即用型治疗食品测试的综合临床前协议	Utume, L.	PDF	N/A	Toward Holistic Solutions to Undernutrition: A Comprehensive Preclinical Protocol for Novel Ready-to-Use Therapeutic Foods Testing
拟南芥生殖阶段莲座叶的年龄依赖性缺铁差异响应	Ngigi, M.	PDF	N/A	Age-dependent differential iron deficiency responses of rosette leaves during reproductive stages in Arabidopsis thaliana
瞬时转录因子耗竭解释了LexA目标启动子对轻度DNA损伤的多样性单细胞响应	Galbusera, L.	PDF	N/A	Transient transcription factor depletions explain diverse single-cell responses of LexA target promoters to mild DNA damage
ST6GAL1介导的肿瘤相关巨噬细胞唾液酸连接转换促进抗炎细胞中携带α2,6-唾液酸化的促癌纳米管形成	Dipta, P.	PDF	N/A	ST6GAL1-mediated sialyl linkage switching in tumor-associated macrophages drives cancer-promoting nanotubes carrying α2,6-sialylation in anti-inflammatory cells
静脉注射猪血浆胞外颗粒对大鼠的可行性——一项急性研究	Chernavsky, N.	PDF	N/A	Feasibility of intravenous injections of pig plasma extracellular particles into rats -- an acute study
结合13C、15N和2H测量海洋浅水海绵的摄食和代谢活动——一项试点研究	Stratmann, T.	PDF	N/A	Combining 13C, 15N, and 2H to measure feeding and metabolic activity in marine, shallow-water sponges - A pilot study
利用多时相和多传感器遥感数据预测林地鸟类物种栖息地	Kuzmich, R. J.	PDF	N/A	Predicting woodland bird species habitat with multi-temporal and multisensor remote sensing data
大规模信息先验以更好地预测稀有树相关微生境的局部发生率	Cottais, P.	PDF	N/A	Large-scale informative priors to better predict the local occurrence rate of a rare tree-related microhabitat
深层土壤微生物群落的功能组成随橡树死亡而变化	Goodman, A. C.	PDF	N/A	Functional composition of deep soil microbial communities changes with oak mortality
在自然啮齿动物种群中，超级传播者具有较低的肠道微生物α多样性以及独特的肠道微生物组成。	Wanelik, K. M.	PDF	N/A	Superspreaders have lower gut microbial alpha-diversity and distinct gut microbial composition in a natural rodent population
由凝聚蛋白和CTCF调控的基因表达统一模型	Choudhary, C.	PDF	N/A	A unified model of gene expression control by cohesin and CTCF
使用空间分子成像技术对固定在福尔马林固定石蜡包埋（FFPE）组织上的整个蛋白质编码人类转录组（18933-plex）进行亚细胞成像	Khafizov, R.	PDF	N/A	Sub-cellular Imaging of the Entire Protein-Coding Human Transcriptome (18933-plex) on FFPE Tissue Using Spatial Molecular Imaging
稳态和刺激下人类骨骼肌细胞代谢性状相关基因调控的功能性解析	Nishino, K.	PDF	N/A	Functional dissection of metabolic trait-associated gene regulation in steady state and stimulated human skeletal muscle cells
在外部机械刺激下，悬浮成纤维细胞片中的力学感应复合物发生动态重塑	Suzuki, M.	PDF	N/A	Dynamic remodeling of mechano-sensing complexes in suspended fibroblast cell-sheets under external mechanical stimulus
gplasCC：从任何细菌物种的短读测序数据中对质粒进行分类和重建	Paganini, J. A.	PDF	N/A	gplasCC: classification and reconstruction of plasmids from short-read sequencing data for any bacterial species
一个强大的通用风险因素差异共表达分析框架	Bass, A. J.	PDF	N/A	A powerful framework for differential co-expression analysis of general risk factors
使用转录组规模上下文扩展单细胞的密集表示	Ho, N.	PDF	N/A	Scaling Dense Representations for Single Cell with Transcriptome-Scale Context
RCVT：一种用于量化系统基因组学中分类群间组成偏倚的新型诊断方法	Steenwyk, J. L.	PDF	N/A	RCVT: a novel diagnostic to quantify compositional biases among taxa for phylogenomics
使用Deconomix在Python中对组学数据进行反卷积——细胞组成、细胞类型特异性基因调控及背景贡献	Altenbuchinger, M. C.	PDF	N/A	Deconvolution of omics data in Python with Deconomix -- cellular compositions, cell-type specific gene regulation, and background contributions
Martini 3力场中优化的蛋白质-辅料相互作用	Prass, T. M.	PDF	N/A	Optimized Protein-Excipient Interactions in theMartini 3 Force Field
银(I)离子与氨基酸侧链之间的精确相互作用：基于12-6 Lennard-Jones势的从底向上参数化方法	Manciocchi, L.	PDF	N/A	Accurate interaction between silver(I) ion and amino acid side chains with the 12-6 Lennard-Jones potential: a bottom-up parameterization approach
DNA错配修复蛋白MSH6是一种PD-L1表达的新型调节因子。	Brooksbank, K.	PDF	N/A	The DNA Mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression
肝细胞癌相关的AXIN1突变驱动Wnt/β-连环蛋白通路活性降低，这种低水平的通路活性使得癌细胞能够在不依赖微环境的情况下生长，并激活YAP/TAZ信号传导。	Venhuizen, A. J.	PDF	N/A	Hepatocellular carcinoma-associated AXIN1 mutations drive low levels of Wnt/β-catenin pathway activity that allow for niche-independent growth and YAP/TAZ signaling
HIFα异构体特异性活性驱动与VHL相关的肿瘤发生的细胞类型特异性	Lima, J. D. C. C.	PDF	N/A	HIFalpha isoform specific activities drive cell-type specificity of VHL-associated oncogenesis
IKZF2-ERBB4基因融合导致肛门鳞状细胞癌中ERBB4的过度表达，但对ERBB4的抑制并无益处。	RICHON, S.	PDF	N/A	IKZF2-ERBB4 gene fusion leads to ERBB4 overexpression in Anal Squamous Cell Carcinoma but with no benefit for ERBB4 inhibition
microRNA-544a作为关节软骨和骨关节炎中Wnt信号网络的新调节因子	Heluany, C. S.	PDF	N/A	microRNA-544a as a new modulator of the Wnt-signalling network in the articular cartilage and osteoarthritis
Mavacamten促进肌球蛋白头部从开启到关闭的转变，并在松弛的骨骼肌中缩短细丝长度。	Kuehn, M. N.	PDF	N/A	Mavacamten facilitates myosin head ON-to-OFF transitions and shortens thin filament length in relaxed skeletal muscle
性依赖的潜在冷害改变了模型昆虫热耐受性的估计	El-Saadi, M. I.	PDF	N/A	Sex-dependent latent chilling injury changes estimates of thermal tolerance in a model insect
股四头肌运动单元的放电特性及其随收缩水平的变化依赖于膝关节角度	Valencic, T.	PDF	N/A	Motor unit discharge properties of the vastii muscles and their modulation with contraction level depend on the knee-joint angle
针对糖尿病心脏病的靶向糖吞噬ATG8疗法	Mellor, K. M.	PDF	N/A	Targeted glycophagy ATG8 therapy for diabetic heart disease
PlantRing：一种用于解码植物生长、水分关系并创新灌溉技术的高通量可穿戴传感器系统	Sun, T.	PDF	N/A	PlantRing: A high-throughput wearable sensor system for decoding plant growth, water relations and innovating irrigation
一种新的PGRL1旁系同源基因优化了草类光保护的调控，并促进了C4光合作用中的细胞特化。	Nix, S. J.	PDF	N/A	A novel PGRL1 paralog refined the control of photoprotection in grasses and facilitated cell specialisation in C4 photosynthesis
编辑OsPHO1;2的顺式作用元件提高了水稻的磷酸盐转运和产量	Maurya, K.	PDF	N/A	Editing cis-elements of OsPHO1;2 improved phosphate transport and yield in rice
人源间充质基质细胞衍生的线粒体在术后消化道瘘大鼠模型中的治疗潜力：迈向能量纳米生物疗法	Mariani, A.	PDF	N/A	Therapeutic potential of human mesenchymal stromal cell-derived mitochondria in a rat model of post-surgical digestive fistula: towards an energetic nano-biotherapy
爆炸性同步的临近程度决定了神经和经济危机中的网络崩溃和恢复轨迹	Lee, U.	PDF	N/A	Proximity to Explosive Synchronization Determines Network Collapse and Recovery Trajectories in Neural and Economic Crises
通过超解景观构建细胞命运决定的全面图谱	Zhang, X.	PDF	N/A	Constructing a holistic map of cell fate decision by hyper solution landscape
增加的NFAT和NFκB信号传导有助于囊性纤维化患者对烟曲霉感染产生的过度炎症表型。	Bercusson, A.	PDF	N/A	Increased NFAT and NFκB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in cystic fibrosis
追踪癌症免疫治疗中抗原特异性T细胞反应	Shagina, I. A.	PDF	N/A	Tracking antigen-specific T cell response to cancer immunotherapy
金黄色葡萄球菌通过NKG2A介导的天然杀伤细胞免疫调控	Davies, K.	PDF	N/A	NKG2A-mediated immune modulation of natural killer cells by Staphylococcus aureus
分类学变化对亚马逊棕榈植物区系的影响	Stropp, J.	PDF	N/A	Impacts of taxonomic change on the Amazonian palm flora
选择增强了植物多样性与车前草代谢特征之间的关系	Medina-van Berkum, P.	PDF	N/A	Selection strengthens the relationship between plant diversity and the metabolic profile of Plantago lanceolata
保护鬣蜥多样性：通过陆地环境DNA创新实现非本土鬣蜥的快速低成本追踪	Kuijk, J.	PDF	N/A	Safeguarding Iguana diversity: Enabling rapid and low-effort tracking of non-native iguanas through terrestrial eDNA innovations
利用动物追踪进行大规模中毒事件的早期检测	Curk, T.	PDF	N/A	Using animal tracking for early detection of mass poisoning events
线虫类寄生虫粪类圆线虫是否为犬类动物的动物传染病？——基于群体遗传学的方法。	:iu, Y.	PDF	N/A	Is the nematode Strongyloides stercoralis a zoonosis from dogs? - a population genetics approach.
CGMFinder 从 3H scRNA-seq 数据中识别相关基因模块	Ma, W.	PDF	N/A	CGMFinder Identifies Correlated Gene Modules from 3H scRNA-seq Data
超越运动皮层：对颅内语音神经假体目标位置的脑区评估	Verwoert, M.	PDF	N/A	Moving beyond the motor cortex: a brain-wide evaluation of target locations for intracranial speech neuroprostheses
P4ward：一种用于Protac三元复合物自动建模的平台	Jofily, P.	PDF	N/A	P4ward: an automated modelling platformfor Protac ternary complexes
专家混合模型助力高效且有效的蛋白质理解和设计	Sun, N.	PDF	N/A	Mixture of Experts Enable Efficient and Effective Protein Understanding and Design
Semaglutide类似物增强GLP-1R激活：动态结构与静电学视角	Li, W.	PDF	N/A	Semaglutide Analogues Enhancing GLP-1R Activation: A Dynamic Structural & Electrostatic Perspective
病毒模拟将免疫抑制的结直肠肿瘤微环境重定向为促炎性和CMS1样再生状态	Corry, S. M.	PDF	N/A	Viral mimicry redirects immunosuppressed colorectal tumour landscapes towards a proinflammatory and CMS1-like regenerative state
错配修复缺陷对同基因小鼠模型中转移发生的影响	Laplante, P.	PDF	N/A	Effect of MisMatch Repair Deficiency on metastasis occurrence modelized in a syngeneic mouse model
PAG通过与肌动蛋白结合，协调T细胞免疫突触的功能。	Moore, E. K.	PDF	N/A	PAG orchestrates T cell immune synapse function by binding to actin
基于血液组学的系统特异性死亡风险评估模型	Fuentealba, M.	PDF	N/A	Blood Omics Models for System-Specific Mortality Risk Estimation
单细胞转录组学揭示了人类肠道中肥大细胞的异质性	Hussein, H.	PDF	N/A	Single cell transcriptomics reveal mast cell heterogeneity in the human gut
全球生物医学和生物技术重要真菌属曲霉的物种多样性和分布模式	Riedling, O. L.	PDF	N/A	Global patterns of species diversity and distribution in the biomedically and biotechnologically important fungal genus Aspergillus
利用性别依赖的基因表达模式进行精确的混合单细胞RNA测序样本解卷积	Twa, G. M.	PDF	N/A	Accurate sample deconvolution of pooled snRNA-seq using sex-dependent gene expression patterns
利用金刚石中的氮-空位中心探测纳米尺度电化学现象	Fulton, S.	PDF	N/A	Probing Nanoscale Electrochemical Phenomena with Nitrogen-Vacancy Centers inDiamond
柔软的3D打印肌肉超声仿体，具有结构可调的B模式回声强度	Gillespie, S.	PDF	N/A	Soft, 3D printed muscle ultrasound phantom with structurally tunable B-mode echo intensity
使用InMoose进行批量转录组分析，InMoose是Python中的集成多组学开源环境	Colange, M.	PDF	N/A	Bulk Transcriptomic Analysis with InMoose, the Integrated Multi-Omic Open-Source Environment in Python
解开细胞类型和状态转录程序的纠缠	Wang, J.	PDF	N/A	Disentangling cell type and state transcriptional programs
不同条件下观察到的血栓蛋白质组含量：成功预测血栓淀粉样蛋白（原）性的作用	Kell, D. B.	PDF	N/A	The proteome content of blood clots observed under different conditions: successful role in predicting clot amyloid(ogenicity)
芯片上流体诱导的血管重塑：对抗VEGF疗法的启示	Mirzapour-Shafiyi, F.	PDF	N/A	Flow-Induced Vascular Remodeling On-Chip: Implications for Anti-VEGF Therapy
一个数学模型阐明了在增强子-基因预测中使用的ABC评分公式	Nasser, J.	PDF	N/A	A mathematical model clarifies the ABC Score formula used in enhancer-gene prediction
PD-L1表达受微小RNA加工、Wnt/β-catenin信号通路及化疗在Wilms瘤中的调控。	Desai, K.	PDF	N/A	PD-L1 expression is mediated by microRNA processing, Wnt/β-catenin signaling, and chemotherapy in Wilms tumor
白血病突变蛋白PHF6和PHIP形成一个染色质复合物，抑制髓系白血病干细胞特性。	Pawar, A. S.	PDF	N/A	Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses myeloid leukemia stemness
白血病突变蛋白PHF6和PHIP形成一种染色质复合物，抑制髓系白血病干细胞特性。	Pawar, A. S.	PDF	N/A	Leukemia-mutated proteins PHF6 and PHIP form a chromatin complex that represses myeloid leukemia stemness
β细胞是胰腺导管腺癌发展的关键驱动力	Garcia, C. C.	PDF	N/A	Beta cells are essential drivers of pancreatic ductal adenocarcinoma development
高级别浆液性卵巢癌的单细胞空间图谱揭示了MHC II类分子作为空间肿瘤生态系统和临床结果的关键驱动因素	Perez-Villatoro, F.	PDF	N/A	Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes
知识图谱与机器学习助力神经系统疾病药物研究	Menestrina, L.	PDF	N/A	Knowledge Graph and Machine Learning Help the Research of Drugs Aimed at Neurological Diseases
海湾战争疾病长期影响的表观遗传学研究	Jones, B. C.	PDF	N/A	Epigenetic study of the long-term effects of Gulf War illness
接触钕会减弱胖头鲦鱼（Pimephales promelas）的低氧呼吸反应。	Nykamp, N. M.	PDF	N/A	Exposure to neodymium blunts the hypoxic ventilatory response in fathead minnows (Pimephales promelas)
AtSDR4L及其同源基因在多个种子部位促进种子到幼苗的转变	Lu, B.	PDF	N/A	AtSDR4L and paralog promote seed-to-seedling transition in multiple seed compartments
通过局部润滑修复自身免疫损伤的角膜基质	Efraim, Y.	PDF	N/A	Rebuilding the autoimmune-damaged corneal stroma through topical lubrication
FCRL4和耗竭B细胞特征在肺癌浸润B细胞中	Bryushkova, E. A.	PDF	N/A	FCRL4 and exhausted B cell signature in tumor infiltrating B cells from lung cancer
铬粒素A和卡特斯丁的缺失影响胰腺胰岛稳态、内分泌功能和神经递质	Muntjewerff, E. M.	PDF	N/A	Loss of chromogranin A and catestatin affect pancreatic islet homeostasis, endocrine function, and neurotransmitters
在加拿大北极地区加强数据收集以获取海鸟兼捕信息，结果显示高度变异。	Provencher, J. F.	PDF	N/A	Enhanced data collection in the Canadian Arctic for seabird bycatch information yields highly variable results
药物诱导的癌症持续者的最佳治疗方案涉及释放周期和中间药物剂量。	Corigliano, M.	PDF	N/A	Optimal treatment for drug-induced cancer persisters involves release periods and intermediate drug doses
人类餐后代谢的DNA甲基化和基因表达轨迹	Costeira, R.	PDF	N/A	DNA methylation and gene expression trajectories of human postprandial metabolism
宽频调谐与深部组织光谱检测的磷化铟纳米激光颗粒	Cho, S.	PDF	N/A	Wideband Tuning and Deep-Tissue Spectral Detection of Indium Phosphide Nano-Laser Particles
可微育种：自动微分使得基于梯度的育种策略优化更加高效	Hamazaki, K.	PDF	N/A	Differentiable breeding: Automatic differentiation enables efficient gradient-based optimization of breeding strategies
PqsE在铜绿假单胞菌中作为群体感应转录因子RhlR的适配蛋白发挥作用。	Tchadi, B. V.	PDF	N/A	PqsE acts as an adaptor protein for the quorum-sensing transcription factor RhlR in Pseudomonas aeruginosa
海藻糖支持埃及伊蚊细胞的生长，并调节基因表达和登革病毒复制。	Conway, M. J.	PDF	N/A	Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus replication
通过固态核磁共振揭示白色念珠菌和白色念珠菌的细胞壁结构及棘球白素反应	Dickwella Widanage, M. C.	PDF	N/A	Unveiling Cell Wall Structure and Echinocandin Response in Candida auris and Candida albicans via Solid-State NMR
盘基网柄菌-海分枝杆菌感染模型，是一种强大的抗感染化合物高通量筛选平台	Nitschke, J.	PDF	N/A	The Dictyostelium discoideum - Mycobacterium marinum infection model, a powerful high throughput screening platform for anti-infective compounds
康泰唑地对感染脓肿分枝杆菌的小鼠和人类患者不同组织的分布情况	Li, Q.	PDF	N/A	Distribution of contezolid in different tissues of mice and human patients infected with Mycobacterium abscessus
基于TurboID的邻近标记技术发现ABCF2为动物源性病原体多杀性巴氏杆菌的粘附受体	Wang, F.	PDF	N/A	TurboID-based proximity labeling discovers ABCF2 as an adhesion receptor for the zoonotic pathogen Pasteurella multocida
RNA N6-甲基腺苷修饰与猪繁殖与呼吸综合征病毒感染之间的动态相互作用	Tong, J.	PDF	N/A	Dynamic interplay between RNA N6-methyladenosine modification and porcine reproductive and respiratory syndrome virus infection
即使存在沃尔巴克氏菌，蚊子的发育仍需要胞外微生物的参与。	Serrato-Salas, J.	PDF	N/A	Extracellular microbes are required for mosquito development even in the presence of Wolbachia
原噬菌体的诱导有助于在肠道炎症期间改变肠道噬菌体组	Sinha, A.	PDF	N/A	Prophage induction contributes to alterations in the gut phageome during intestinal inflammation
间歇性抑制性泊沙康唑疗法在减轻慢性恰加斯病实验模型中的心脏和消化道病理损害方面无效。	Jayawardhana, S.	PDF	N/A	Intermittent suppressive posaconazole therapy is ineffective at mitigating cardiac and digestive tract pathologies in an experimental model of chronic Chagas disease
基于KP.2的单价mRNA疫苗能够显著增强对SARS-CoV-2的抗体反应。	Wang, Q.	PDF	N/A	KP.2-based monovalent mRNA vaccines robustly boost antibody responses to SARS-CoV-2
通过结合明确的交联信息，改进AlphaFold 3结构建模	Kosinski, J.	PDF	N/A	Improving AlphaFold 3 structural modeling by incorporating explicit crosslinks
利用小鼠嗜性γ-逆转录病毒促进人类淋巴瘤细胞中的基因编辑	Kumar, M.	PDF	N/A	Facilitating Gene Editing in Human Lymphoma Cells Using Murine Ecotropic γ-Retroviruses
ΔNp63β的差异性转录活性由其同工型特异性的C端编码	McCann, A. A.	PDF	N/A	Differential transcriptional activity of ΔNp63β is encoded by an isoform-specific C-terminus
RNAi介导的HBV抗原关闭通过改变T细胞和B细胞的相互作用，增强了PEGIFNalpha的抗病毒免疫效果。	Zai, W.	PDF	N/A	RNAi-mediated HBV antigen shutdown enhances the antiviral immune effects of PEGIFNalpha via altering T and B cell crosstalk
在钴胺素缺乏的条件下，硅藻生产钴胺素下配体，5,6-二甲基苯并咪唑的过程	Gleason, A. K.	PDF	N/A	Production of the cobalamin lower ligand, 5,6-dimethylbenzimidazole, by a diatom under cobalamin-deplete conditions
基于土壤相关氨氧化菌的快速高通量筛选平台，用于生物硝化抑制剂的发现	Kanellopoulos, A. E.	PDF	N/A	A fast-track, high-throughput screening platform for biological nitrification inhibitors discovery based on soil relevant ammonia oxidizing strains
土壤微生物在模拟根系分泌物中更偏好有机酸而非糖类。	Wiesenbauer, J.	PDF	N/A	Soil microbes prefer organic acids over sugars in simulated root exudation
沙眼衣原体中含SWIB结构域的DNA拓扑异构酶I介导DNA松弛作用	Shen, L.	PDF	N/A	The SWIB domain-containing DNA topoisomerase I of Chlamydia trachomatis mediates DNA relaxation
# BioRxiv 2024-12-02 Papers

标题	作者	PDF链接	代码仓库	Title
靶向噬菌体T4纳米颗粒逆转CD4+人类T细胞中的HIV-1潜伏期	Batra, H.	PDF	N/A	Targeted Bacteriophage T4 Nanoparticles Reverse HIV-1 Latency in CD4+ Human T Cells
内体趋化因子受体信号复合体调控细胞迁移的中心机制	Hahn, H.	PDF	N/A	Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration
撤回：类风湿性关节炎合并尿路感染患者中奇异变形杆菌分离株的免疫学参数	Abdul, F. R.	PDF	N/A	WITHDRAWN: Immunological parameters of Proteus mirabilis isolates in Rheumatoid Arthritis patients with urinary tract infections
整合代谢规模和共存理论	Saavedra, S.	PDF	N/A	Integrating metabolic scaling and coexistence theories
在人类癌细胞中，输入蛋白α在微核中积累，并与基因组不稳定性相关联。	Miyamoto, Y.	PDF	N/A	Importin α accumulates in micronuclei and associates with genomic instability in human cancer cells
揭示早期人类B细胞淋巴发生调控机制及其在B细胞急性淋巴母细胞白血病发病机制中的意义	Planell, N.	PDF	N/A	Uncovering the regulatory landscape of early human B-cell lymphopoiesis and its implications in the pathogenesis of B-cell acute lymphoblastic leukemia
TEMPTED：纵向微生物组研究的时间感知降维方法	Shi, P.	PDF	N/A	TEMPTED: Time-Informed Dimensionality Reduction for Longitudinal Microbiome Studies
后顶叶内侧皮层中的中尺度功能架构	Hira, R.	PDF	N/A	Mesoscale functional architecture in medial posterior parietal cortex
通过内侧视前区异质神经元集群对女性性欲的射精后抑制	Ishii, K. K.	PDF	N/A	Post-ejaculatory Inhibition of Female Sexual Drive via Heterogeneous Neuronal Ensembles in the Medial Preoptic Area
宽过渡态系综作为酶催化关键组分	Jara, G. E.	PDF	N/A	Wide Transition-State Ensemble as Key Component for Enzyme Catalysis
通过三维几何形态测量法分析泰坦龙类（恐龙，蜥脚类）后肢形态的演化，揭示了宽步态姿势作为巨型化的适应性特征。	Paramo Blazquez, A.	PDF	N/A	Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D Geometric Morphometrics reveals wide-gauge posture as an exaptation for gigantism
Vangl-Celsr极性复合物在胞内囊泡运输中的紊乱是导致气管-食管形态发生先天性异常的潜在原因。	Edwards, N. A.	PDF	N/A	Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis
斑马鱼中的折叠与融合神经形成过程需要Vangl2蛋白的参与。	MacGowan, J.	PDF	N/A	Fold-and-fuse neurulation in zebrafish requires Vangl2
USP7抑制促进老年骨质疏松小鼠早期骨整合	Zhou, F.	PDF	N/A	USP7 Inhibition Promotes Early Osseointegration in Senile Osteoporotic Mice
在缺乏P物质和CGRPα信号的小鼠中，疼痛持续存在。	MacDonald, D. I.	PDF	N/A	Pain persists in mice lacking both Substance P and CGRPα signaling
海马体中空间支架的情节记忆和联想记忆	Chandra, S.	PDF	N/A	Episodic and associative memory from spatial scaffolds in the hippocampus
神经信号反卷积分析的可解释深度学习	Tolooshams, B.	PDF	N/A	Interpretable deep learning for deconvolutional analysis of neural signals
选择性上皮表达KRASG12D突变在Oncopigs中驱动胰腺导管性肿瘤	Jara, C. P.	PDF	N/A	Selective epithelial expression of KRASG12D mutation drives ductal pancreatic neoplasia in Oncopigs
扣带皮层塑造了出生后早期社会发声的发展	Nagarajan, G.	PDF	N/A	Cingulate cortex shapes early postnatal development of social vocalizations
三重态态布居对GFP型荧光及光漂白的影响	Byrdin, M.	PDF	N/A	Impact of Triplet State Population on GFP-type Fluorescence and Photobleaching
支配肝脏的迷走神经感觉神经元在喂食高脂饮食的小鼠中，对于脂肪肝和焦虑样行为的发展起着不可或缺的作用。	Hwang, J.	PDF	N/A	Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis and anxiety-like behavior in mice fed a high-fat diet.
两个对抗性的基因调控网络在低温下驱动拟南芥根毛生长	Urzua, T.	PDF	N/A	Two antagonistic gene regulatory networks drive Arabidopsis root hair growth at low temperature
一个包含超过34,000种脊椎动物的物种形成速率、不确定性以及存在-缺失矩阵的数据集	Vasquez-Restrepo, J. D.	PDF	N/A	A dataset containing speciation rates, uncertainty, and presence-absence matrices for more than 34,000 vertebrate species
反馈在视觉工作记忆和长期记忆期间，均能调节皮层反应的空间调谐性。	Woodry, R.	PDF	N/A	Feedback scales the spatial tuning of cortical responses during both visual working memory and long-term memory
在抗病毒反应中，Fish CDK2招募Dtx4通过泛素化降解TBK1	Lu, L.-F.	PDF	N/A	Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response
腹侧苍白球的GABA能神经元在雄性大鼠中驱动摄食行为，但在雌性大鼠中则不然。	Scott, A.	PDF	N/A	Ventral pallidal GABAergic neurons drive consumption in male, but not female rats
家犬驯化过程中的基因型和表型结果	Sweetalana,	PDF	N/A	Genotypic and phenotypic consequences of domestication in dogs
有限的证据表明，概率性提示对光栅诱发的事件相关电位和方向解码性能有影响。	den Ouden, C.	PDF	N/A	Limited evidence for probabilistic cueing effects on grating-evoked event-related potentials and orientation decoding performance
贝叶斯奥卡姆剃刀优化复杂系统模型的方法	Wang, C.	PDF	N/A	Bayesian Occam's Razor to Optimize Models for Complex Systems
氘代谢成像表型通过葡萄糖转化动力学揭示小鼠胶质母细胞瘤的异质性	Simoes, R. V.	PDF	N/A	Deuterium Metabolic Imaging Phenotypes Mouse Glioblastoma Heterogeneity Through Glucose Turnover Kinetics
新生儿血液中自闭症谱系障碍的性别特异性DNA甲基化特征	Mouat, J. S.	PDF	N/A	Sex-specific DNA methylation signatures of autism spectrum disorder in newborn blood
坏死导致PolgD257A突变小鼠对结核分枝杆菌的易感性增加	Mabry, C. J.	PDF	N/A	Necrosis drives susceptibility to Mycobacterium tuberculosis in PolgD257A mutator mice
实验诱导的疼痛和感觉异常对无疼痛年轻个体中袖带加压参数变化的响应不同	Skalski, J.	PDF	N/A	Experimentally induced pain and paresthesia respond differently to parameter changes of cuff-based compression in pain-free young individuals
角质形成细胞向皮肤鳞状细胞癌的遗传进化	Tandukar, B.	PDF	N/A	Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma
在早期儿童时期，皮层区域的一个子集表现出类似于成人的功能网络模式。	Tu, J. C.	PDF	N/A	A Subset of Cortical Areas Exhibit Adult-like Functional Network Patterns in Early Childhood
微塑料作为抗菌素耐药性的新型促进剂：浓度、组成和尺寸对大肠杆菌多重耐药性的影响	Gross, N.	PDF	N/A	Microplastics as a novel facilitator for antimicrobial resistance: Effects of concentration, composition, and size on Escherichia coli multidrug resistance
空间转录组分析揭示HDAC抑制通过调节小胶质细胞动态在小鼠中保护免受缺血性中风	Jayaraj, K.	PDF	N/A	Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice
调节相互抑制的机制控制UNC-13的功能切换	Liu, H.	PDF	N/A	Mechanism that regulates the mutual inhibition controls functional switch of UNC-13
青春期对促肾上腺皮质激素释放因子受体1的拮抗作用会导致行为可塑性和杏仁核转录组特征的持续性、性别特异性变化。	Martz, J.	PDF	N/A	Peripubertal antagonism of corticotropin-releasing factor receptor 1 results in sustained, sex-specific changes in behavioral plasticity and the transcriptomic profile of the amygdala
揭示具有微生物组相互作用特性的马铃薯品种，以实现可持续农业生产	Zhao, T.	PDF	N/A	Unveiling the potato cultivars with microbiome interactive traits for sustainable agricultural production
wtf杀手减数分裂驱动因子的功能性限制	Srinivasa, A. N.	PDF	N/A	Functional constraints of wtf killer meiotic drivers
缺铁会导致大豆根部转录发生变化，进而破坏其耐旱性。	Hasan, M. R.	PDF	N/A	Fe deficiency causes transcriptional shift in roots leading to disruption of drought tolerance in soybean
个人空间与群体灾难中的集体行为	Lugo, I.	PDF	N/A	The personal space and the collective behavior of crowd disasters
味蕾中的死亡：死亡的味觉受体细胞被胶质样I型细胞吞噬	Wilson, C. E.	PDF	N/A	Death in the taste bud: engulfment of dying taste receptor cells by glial-like Type I cells
社会结构对和尚鹦鹉发声灵活性的影响	Smeele, S. Q.	PDF	N/A	The effect of social structure on vocal flexibility in monk parakeets
在高壁面剪切应力条件下，几种PfEBA和PfRH配体对恶性疟原虫疟疾血期生长至关重要。	Kals, E.	PDF	N/A	Under conditions of high wall shear stress, several PfEBA and PfRH ligands are important for Plasmodium falciparum malaria blood-stage growth
催产素受体调控草原田鼠的滥交行为及发育	Sharma, R.	PDF	N/A	Oxytocin receptor controls promiscuity and development in prairie voles
通过味觉受体检测细菌可启动细胞免疫反应	Mazariegos, A. N.	PDF	N/A	Detection of bacteria through taste receptors primes the cellular immune response
果蝇在特征贫乏环境中的空间学习	Chen, Y.	PDF	N/A	Spatial learning in feature-impoverished environments in Drosophila
Lgl在有丝分裂退出时重置Par复合物膜加载，以实现不对称神经干细胞分裂	LaFoya, B.	PDF	N/A	Lgl resets Par complex membrane loading at mitotic exit to enable asymmetric neural stem cell division
等压标记在MaxQuant中的更新	Ferretti, D.	PDF	N/A	Isobaric labeling update in MaxQuant
照亮根土力学	Le Houx, J.	PDF	N/A	Illuminating root-soil mechanics
顶枕叶伽马经颅交流电刺激对视觉空间注意任务中行为表现和神经活动的影响	Zheng, T.	PDF	N/A	After-effects of Parieto-occipital Gamma Transcranial Alternating Current Stimulation on Behavioral Performance and Neural Activity in Visuo-spatial Attention Task
模拟欧洲范围内人类蜱传脑炎（TBE）发生概率的时空年度变化	Dagostin, F.	PDF	N/A	Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe
通过激光诱导的Soret效应实现亚稳态相分离液滴生成及长时间DNA富集	Kobayashi, M.	PDF	N/A	Metastable phase-separated droplet generation and long-time DNA enrichment by laser-induced Soret effect
通过多模态方法分析亚麻荠和高粱对环境胁迫的响应特性	Seitz, K. A.	PDF	N/A	Characterizing the Responses of Camelina and Sorghum to Environmental Stress through a Multi-Modal Approach
对多样性杂交小鼠研究中寿命的分析确定了多个与长寿相关的基因座	Mullis, M. N.	PDF	N/A	Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci
委内瑞拉Llanos地区三种空中捕食蝙蝠的饮食与食性生态位划分	Azofeifa Romero, Y.	PDF	N/A	Diet and trophic niche partitioning of three aerial hawking bat species in the Venezuelan Llanos
海拔和海洋屏障塑造了新西兰卡波卡波瓦伊（Uropetala）蜻蜓的分布、扩散和多样性	Tolman, E. R.	PDF	N/A	Elevational and Oceanic Barriers Shape the Distribution, Dispersal and Diversity of Aotearoa's Kapokapowai (Uropetala) Dragonflies
基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论的碱基对结合能计算	Deka, N.	PDF	N/A	Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT
通过自然转化在人类肠道微生物组中测量微生物群落范围内的抗生素抗性传播	Chowdhury, N. N.	PDF	N/A	Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome
对Lasius蚁属的基因组数据进行去污染处理，以实现准确的物种划分和杂交检测	Jecha, K.	PDF	N/A	Decontaminating genomic data for accurate species delineation and hybrid detection in the Lasius ant genus
体内网络活动的调节驱动了轴突起始段处轴-轴突突触的纳米尺度重构	Compans, B.	PDF	N/A	In vivo modulation of network activity drives the nanoscale reorganisation of axo-axonic synapses at the axon initial segment
青春期和成年期怀孕期间的压力会影响下丘脑中的组蛋白乙酰化调节因子。	Luther, L. A.	PDF	N/A	Stress during puberty and adulthood pregnancy impact histone acetylation regulators in the hypothalamus
Lats1/2对于发育中的血管重塑和适应剪切应力的生物力学适应至关重要。	Cowdin, M. A.	PDF	N/A	Lats1/2 are essential for developmental vascular remodeling and biomechanical adaptation to shear stress
古老社会染色体上超基因的重复进化	Lajmi, A.	PDF	N/A	Repeated evolution of supergenes on an ancient social chromosome
森林不仅仅是树木：单倍型与推断的溯祖图	Fritze, H.	PDF	N/A	A forest is more than its trees: haplotypes and inferred ARGs
GluA1的细胞质尾部调控细胞内AMPA受体的运输以及对齿状回GABA能中间神经元的突触传递，调节对新奇刺激的反应	Leana-Sandoval, G.	PDF	N/A	The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty
背外侧前额叶皮层细胞类型特异性增强子。	He, J.	PDF	N/A	Cell Type Specific Enhancers for Dorsolateral Prefrontal Cortex.
转录调控元件的方向性	Chen, Y.	PDF	N/A	Directionality of Transcriptional Regulatory Elements
电生理图作为一种功能性读数，用于评估果蝇黑腹果蝇神经退行性变模型中的神经元完整性。	Manuel, N.	PDF	N/A	Electroretinograms as a functional readout of neuronal integrity in neurodegeneration models of Drosophila melanogaster
嘌呤能受体P2Y13调控室管膜下区成年神经干细胞的激活与分裂模式	Paniagua-Herranz, L.	PDF	N/A	Purinergic Receptor P2Y13 Controls Activation and Mode of Division in Subependymal Adult Neural Stem Cells
H5N1适应牛细胞的多基因决定因素	Turnbull, M. L.	PDF	N/A	POLYGENIC DETERMINANTS OF H5N1 ADAPTATION TO BOVINE CELLS
分枝杆菌核小体相关蛋白NapM表现出应激诱导的隔膜定位，并调节细胞膜基因表达	Milcarz, K.	PDF	N/A	The mycobacterial nucleoid-associated protein NapM exhibits stress-induced septal localization and modulates cell envelope gene expression
对涡虫再生特异性的比较分析揭示了轴向cWnt信号梯度对组织极性的贡献。	Cleland, J. P.	PDF	N/A	A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient.
出生体重差异、基因表达与DNA甲基化：双胞胎表观遗传学研究的综述	Wadji, D. L.	PDF	N/A	Birth weight discordance, gene expression, and DNA methylation: A review of epigenetic twin studies
相对于群体成员的空间位置会影响狐獴（Suricata suricatta）的体重增加	Mosia, R.	PDF	N/A	Spatial position relative to group members affects weight gain in meerkats (Suricata suricatta)
光学层析成像技术在旋转驱动下重建多散射样品的3D运动和结构	Moser, S.	PDF	N/A	Optical tomography reconstructing 3D motion and structure of multiple-scattering samples under rotational actuation
耶氏解脂耶氏酵母中基因编码报告基因的总体评价	Zhang, H.	PDF	N/A	General assessment of genetically-encoded reporters in Yarrowia lipolytica
Alevin-fry-atac 利用虚拟颜色实现单细胞ATAC-seq数据的快速且低内存消耗的基因组伪比对，从而进行准确的数据映射。	Singh, N. P.	PDF	N/A	Alevin-fry-atac enables rapid and memory frugal mapping of single-cell ATAC-seq data using virtual colors for accurate genomic pseudoalignment
extgfa：一种低内存的基因组图谱磁盘表示方法	Dabbaghie, F.	PDF	N/A	extgfa: a low-memory on-disk representation of genome graphs
斜面显微镜中的主动远程聚焦稳定	Nguyen, D. T.	PDF	N/A	Active Remote Focus Stabilization in Oblique Plane Microscopy
Cetuximab-IRDye800偶联物在EGFR过表达肿瘤中的荧光和光声信号的时间动力学	Saad, M. A.	PDF	N/A	Temporal dynamics of fluorescence and photoacoustic signals of a Cetuximab-IRDye800 conjugate in EGFR-overexpressing tumors
重新评估爱泼斯坦-巴尔病毒（EBV）与美国乳腺癌之间的关联	Hu, C. C.	PDF	N/A	Reevaluating the Association Between Epstein-Barr Virus (EBV) and Breast Cancer in the United States
通过sEV液体活检揭示miR-451a和miR-142-3p作为非小细胞肺癌的预后标志物	Burdiel Herencia, M.	PDF	N/A	Unveiling miR-451a and miR-142-3p as Prognostic Markers in NSCLC via sEV Liquid Biopsy
正电子发射断层扫描（PET）示踪剂能够成像高CD73表达的癌症。	Dobelmann, C.	PDF	N/A	Positron emission tomography (PET) tracer enables imaging of high CD73 expression in cancer
细胞自主性游离脂肪酸受体4-ChemR23信号级联保护心肌细胞免受缺血损伤	Puccini, S.	PDF	N/A	A Cell Autonomous Free fatty acid receptor 4 - ChemR23 Signaling Cascade Protects Cardiac Myocytes from Ischemic Injury
在Physcomitrella光生物反应器中生产蜘蛛丝蛋白的重组生产	Ramezaniaghdam, M.	PDF	N/A	Recombinant production of spider silk protein in Physcomitrella photobioreactors
产后第一年内存在亲子关系障碍的母亲的情绪处理：一项改编的fMRI情绪GoNoGo任务的结果	Eckstein, M.	PDF	N/A	Emotion processing in mothers with bonding disorder during the first year postpartum: Results of an adapted fMRI emotional GoNoGo Task
短暂的新生儿视觉剥夺对人类腹侧枕颞皮层发育的影响	Mattioni, S.	PDF	N/A	Impact of a transient neonatal visual deprivation on the development of the ventral occipito-temporal cortex in humans
LRRK2 G2019S突变在感染性结肠炎模型中激发了细胞内在的中性粒细胞效应功能增强和肠道炎症	Pei, J.	PDF	N/A	LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
红李（Leea rubra Blume）抗氧化、抗糖尿病和抗菌活性的体外研究	Mai, H. V.	PDF	N/A	In Vitro Studies of Antioxidant, Antidiabetic, and Antibacterial Activities of Leea rubra Blume
在小鼠和人类中移植后高度功能性效应CD8+ T细胞程序的鉴定	Cohen, G. S.	PDF	N/A	Identification of a Highly Functional Effector CD8+ T Cell Program After Transplantation in Mice and Humans
欧洲亚型蜱传脑炎病毒在韩国的兴起（2005-2014年）可能与人类活动有关	Kovalev, S. Y.	PDF	N/A	European Subtype Tick-Borne Encephalitis Virus Emergence In South Korea (2005 - 2014) Can Be Associated With Human Activity
TTF2通过将TRAIP泛素连接酶与Pol epsilon耦合，驱动有丝分裂复制体的解体和MiDAS。	FUJISAWA, R.	PDF	N/A	TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Pol epsilon
细胞类型特异性体内蛋白质组与多拷贝突变型甲硫氨酰tRNA合成酶小鼠品系	Schuman, E. M.	PDF	N/A	Cell type-Specific In Vivo Proteomes with a Multi-copy Mutant Methionyl t-RNA Synthetase Mouse Line
利用原子力显微镜绘制海鞘胚胎在卵裂阶段的单细胞流变学图谱	Kotani, T.	PDF	N/A	Mapping single-cell rheology of ascidian embryos in the cleavage stages using AFM
皮质微管作为模板，组织了胞吐作用的纳米级图案化。	Lindeboom, J.	PDF	N/A	Cortical microtubules act as a template to organize nano-scale patterning of exocytosis
两种新型红色FRET ERK生物传感器，波长范围为670-720纳米。	DeCuzzi, N. L.	PDF	N/A	Two Novel Red-FRET ERK Biosensors in the 670-720nm Range.
双皮质素结构域蛋白ZYG-8对微管的硬化作用有助于在秀丽隐杆线虫合子分裂过程中纺锤体的定向	Cueff, L.	PDF	N/A	Microtubule stiffening by doublecortin-domain protein ZYG-8 contributes to spindle orientation during C. elegans zygote division
Rbfox1和mir-33调控JAK/STAT信号在果蝇成体肌生成中的多效性作用	Mukherjee, A.	PDF	N/A	Rbfox1 and mir-33 regulate pleiotropic roles of JAK/STAT signalling during adult myogenesis in Drosophila melanogaster
不同的细胞和分子机制导致几丁质沉积，这有助于D. melanogaster中两种几丁质合成酶的特异性。	Bertran-Mas, J.	PDF	N/A	Different cellular and molecular mechanisms of chitin deposition contribute to the specificity of the two chitin synthases in D. melanogaster.
饮食中的余甘子（印度醋栗，Amla）可提高果蝇模型中早期营养不良的生育力和抗氧化应激能力。	Padmaraj, P.	PDF	N/A	Dietary Phyllanthus emblica L. (Indian gooseberry, Amla) improves fecundity and resistance to oxidative stress in a Drosophila melanogaster model of early-life malnutrition.
海洋硅藻热耐受性的演变：热胁迫下的代谢策略。	Aranguren-Gassis, M.	PDF	N/A	Evolution of thermal tolerance in marine diatoms: Metabolic strategies under heat stress.
细胞对冷冻-解冻应激产生类似静止状态的趋同适应	Tvishamayi, C.	PDF	N/A	Convergent cellular adaptation to a quiescence-like state in response to freeze-thaw stress
近似贝叶斯计算支持了人类囊胚阶段胚胎中染色体嵌合现象的高发生率。	Yang, Q.	PDF	N/A	Approximate Bayesian computation supports a high incidence of chromosomal mosaicism in blastocyst-stage human embryos
鉴定并分析扁虫Hofstenia miamia中的微小RNA的发育特征	Duan, Y.	PDF	N/A	Identification and developmental profiling of microRNAs in the acoel worm Hofstenia miamia
Indel驱动的刀豆氨酸tRNA编辑去乙酰酶CtdA的进化	Mayans, O.	PDF	N/A	Indel-driven evolution of the canavanine tRNA-editing deacetylase enzyme CtdA
无标记下使用全息断层显微镜和U-Net对内皮细胞线粒体进行可视化与分割	Michael, R.	PDF	N/A	Label-Free Visualization and Segmentation of Endothelial Cell Mitochondria Using Holotomographic Microscopy and U-Net
在人类肾脏中整合空间多重蛋白质成像和转录组学，追踪近端小管再生潜力的时间线	Asghari, M.	PDF	N/A	Integration of spatial multiplexed protein imaging and transcriptomics in the human kidney tracks the regenerative potential timeline of proximal tubules
多特征AI集成与投票系统在MAPKAPK2抑制剂发现中的优化	Chen, H.	PDF	N/A	Optimization of a Multi-Feature AI Ensemble and Voting System for MAPKAPK2 Inhibitor Discovery
使用反事实的定量归因	Adjavon, D.-Y.	PDF	N/A	Quantitative Attributions with Counterfactuals
涂层刷的电荷分布驱动染色体间的吸引力	Sorichetti, V.	PDF	N/A	Charge distribution of coating brush drives inter-chromosome attraction
使用冷冻电子断层扫描技术对染色质生物分子凝聚物进行定量空间分析	Zhou, H.	PDF	N/A	Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography
黏附-悬浮转变促进黑色素瘤的转移扩散	Lee, D. K.	PDF	N/A	Adherent-to-suspension transition promotes melanoma metastatic dissemination
林奇综合征相关尿路上皮癌中受限的超突变及TERT启动子突变的缺失	Nikkola, J.	PDF	N/A	Constrained hypermutation and absence of TERT promoter mutations in Lynch syndrome-associated urothelial cancer
一种新型RyR2选择性稳定剂可预防和改善应激诱导的室性心动过速中的严重心律失常	Kurebayashi, N.	PDF	N/A	A novel RyR2-selective stabilizer prevents and ameliorates severe arrhythmias in stress-induced ventricular tachycardia
大肠杆菌应激反应调节子中的动态异质性介导基因激活和抗菌肽耐受性	Blassick, C. M.	PDF	N/A	Dynamic heterogeneity in an E. coli stress response regulon mediates gene activation and antimicrobial peptide tolerance
一种多层次形式体系，用于捕捉上皮-间质可塑性中混合表型的特征	Hari, K.	PDF	N/A	A multi-level formalism to capture the characteristics of hybrid phenotypes in Epithelial-Mesenchymal Plasticity
fluxTrAM：将基于示踪剂的代谢组学数据整合到原子分辨率的基因组规模代谢网络中，用于代谢通量分析	Huang, L.	PDF	N/A	fluxTrAM: Integration of tracer-based metabolomics data into atomically resolved genome-scale metabolic networks for metabolic flux analysis
非甾体抗炎药物的代谢组学反应	Ghosh, S.	PDF	N/A	Metabolomic Response to Non-Steroidal Anti-Inflammatory Drugs
规范模型揭示了青春期前儿童在精神病理学维度上存在不同的皮层异常	Deng, Q.	PDF	N/A	Normative models reveal distinct cortical abnormalities to dimensions of psychopathologies in preadolescents
干扰素-γ通过IRF1对炎症NF-κB靶基因的表观遗传调控	Mishra, B.	PDF	N/A	Epigenetic Regulation of Inflammatory NF-κB Target Genes by IFN-γ via IRF1
Zfh1与Nau之间的相互作用通过一个由mir-9a介导的负反馈回路，在果蝇（Drosophila melanogaster）中调控Rbfox1及其靶标Stat92E的肌源性阶段依赖性表达。	Mukherjee, A.	PDF	N/A	The interplay between Zfh1 and Nau orchestrates the myogenic stage-dependent expression of Rbfox1 and its target Stat92E via a mir-9a-mediated negative feedback loop in Drosophila melanogaster
从讣告中识别家庭结构并将其与电子健康记录中的患者进行匹配。	Mayer, J. G.	PDF	N/A	Identifying Family Structures from Obituaries and Matching them to Patients in an Electronic Heath Record.
深度学习与浅层混合纳米孔-Illumina测序用于经济实惠且准确的检测种系变异。	Gambardella, G.	PDF	N/A	Deep-leaning and shallow hybrid Nanopore-Illumina sequencing for affordable and accurate detection of germline variants.
CEACAM1通过脂噬依赖的铁死亡介导心房颤动，靶向ABCA1	Hu, W.-w.	PDF	N/A	CEACAM1 Targets ABCA1 to Mediate Atrial Fibrillation via Lipophagy-Dependent Ferroptosis
独特的最小临床截短突变对BRCA1相互作用组的不同重塑	Chen, J.	PDF	N/A	Differential Remodeling of the BRCA1 Interactome by a Unique Minimal Clinical Truncation Mutation
从质谱指纹图谱进行基因本体的大规模预测揭示了新的代谢基因功能	Vavricka, C.	PDF	N/A	Genome-scale prediction of gene ontology from mass fingerprints reveals new metabolic gene functions
Cycledesigner 利用 RFdiffusion 和 HighFold 设计针对特定目标的环肽结合剂	Zhang, C.	PDF	N/A	Cycledesigner Leveraging RFdiffusion and HighFold to Design Cyclic Peptide Binders for Specific Targets
古基因组学支持东地中海和西地中海印欧语言之间存在深远分化。	Yediay, F. E.	PDF	N/A	Ancient genomics support deep divergence between Eastern and Western Mediterranean Indo-European languages
烟草烟雾改变了肺腺癌中突变、选择和上位性的格局	Dasari, K.	PDF	N/A	Tobacco smoke alters the landscape of mutation, selection, and epistasis in lung adenocarcinoma
NEFFy：一种用于计算有效序列数量的多功能工具	Haghani, M.	PDF	N/A	NEFFy: A Versatile Tool for Computing the Number of Effective Sequences
在非小细胞肺癌中，细胞间的融合在药物选择下赋予了适应性优势	Shultes, P. V.	PDF	N/A	Cell-Cell Fusion in NSCLC Confers a Fitness Benefit Under Drug Selection
长期高温影响甘蓝型油菜种子的成熟度和种皮完整性	Prabhullachandran, U.	PDF	N/A	Long-term high temperatures affect seed maturation and seed coat integrity in Brassica napus
单细胞海洋捕食者的全球种群结构	Latorre, F.	PDF	N/A	Global population structure of a unicellular marine predator
网络结构和适应性觅食对物种丰富的植物-传粉者群落传粉服务的影响	Valdovinos, F. S.	PDF	N/A	Effect of network structure and adaptive foraging on pollination services of species-rich plant-pollinator communities
研究设计和在生物银行规模数据集中对有害罕见变异的采样	Steiner, M. C.	PDF	N/A	Study design and the sampling of deleterious rare variants in biobank-scale datasets
拟谷盗近缘物种基因组中卫星DNA的动态演化	Veseljak, D.	PDF	N/A	Dynamic evolution of satellite DNAs drastically differentiates the genomes of Tribolium sibling species
从长读取重叠区域估计基因组大小	Hall, M. B.	PDF	N/A	Genome size estimation from long read overlaps
人脑和猴脑中的连接性：探讨穹窿在轻度认知障碍和阿尔茨海默病中的因果作用	Pelekanos, V.	PDF	N/A	Connectivity in the human and the monkey brain probes causal involvement of the fornix in Mild Cognitive Impairment and Alzheimer's Disease
在小鼠阿尔茨海默病、动脉粥样硬化及阿尔茨海默病合并动脉粥样硬化模型中表征血管功能	Eyre, B.	PDF	N/A	Characterizing vascular function in mouse models of Alzheimer's disease, atherosclerosis, and mixed Alzheimer's and atherosclerosis
周围炎症刺激导致小胶质细胞吞噬谷氨酸能输入，并降低伏隔核D1中型多棘神经元的兴奋性。	Nakajima, S.	PDF	N/A	Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult
突触乙酰胆碱通过烟碱受体在基底外侧杏仁核中诱导出尖波涟漪。	Bratsch-Prince, J. X.	PDF	N/A	Synaptic acetylcholine induces sharp wave ripples in the basolateral amygdala through nicotinic receptors
异步亚基转换先于乙酰胆碱受体激活	Thompson, M. J.	PDF	N/A	Asynchronous subunit transitions precede acetylcholine receptor activation
MEG信号揭示了顶叶前额叶皮层中手臂姿势编码和内在运动计划的存在。	Blohm, G.	PDF	N/A	MEG signals reveal arm posture coding and intrinsic movement plans in parietofrontal cortex
用于连续测量亚100纳摩尔尼古丁的荧光蛋白生物传感器的水凝胶封装	Nichols, A. L.	PDF	N/A	Hydrogel encapsulation of a designed fluorescent protein biosensor for continuous measurements of sub-100 nanomolar nicotine
综合现象学和脑连接性研究表明，在高级冥想（如禅那）中，非线性处理发生了变化。	Potash, R. M.	PDF	N/A	Integrated phenomenology and brain connectivity demonstrate changes in nonlinear processing in jhana advanced meditation
过度活跃的神经网络促进阿尔茨海默病小鼠模型中的tau蛋白扩散	Barbour, A. J.	PDF	N/A	Hyperactive neuronal networks facilitate tau spread in an Alzheimer's disease mouse model
ASH1L通过动态调节染色质环境调控人类神经元结构与功能	Jhanji, M.	PDF	N/A	Dynamic Regulation Of The Chromatin Environment By ASH1L Modulates Human Neuronal Structure And Function
对埃及伊蚊基因表达的分析表明，蚊子发育早期阶段的遗传调控发生了变化。	dos Santos, R. C.	PDF	N/A	Analysis of gene expression in Aedes aegyptisuggests changes in early genetic control of mosquito development
双语接触与性别塑造婴儿对语音特征大脑反应的发展轨迹	Puertollano, M.	PDF	N/A	Bilingual Exposure and Sex Shape Developmental Trajectories of Brain Responses to Speech-Sound Features in Infants
PDGFRα+间充质基质细胞在前列腺发育过程中促进上皮谱系的形成	Maiti, D.	PDF	N/A	PDGFRα+ Mesenchymal Stromal Cells Contribute to Epithelial Lineages during Prostate Development
通过dPGC1控制线粒体动力学限制了Yorkie诱导的果蝇致癌性生长	Sew, W. Q. G.	PDF	N/A	Control of mitochondrial dynamics by dPGC1 limits Yorkie-induced oncogenic growth in Drosophila
果蝇对细菌肽聚糖的感知反应整合了正负信号	Montanari, M.	PDF	N/A	Drosophila's sensory responses to bacterial peptidoglycan integrates positive and negative signals
海洋蠕虫Capitella teleta对神经化学操纵非常敏感，这一发现是通过一种新型的高通量行为工具揭示的。	Hendershot, M.	PDF	N/A	The marine worm Capitella teleta is sensitive to neurochemical manipulation, as revealed via a novel high-throughput behavioural tool
雌性虎皮鹦鹉更倾向于选择与自己觅食技能不同的雄性。	Zou, Y.	PDF	N/A	Female budgerigars prefer males with foraging skills that differ from their own
前额叶星形胶质细胞的过度激活通过中枢犬尿氨酸的代谢途径损害认知	Beilmann, V.	PDF	N/A	Overactivation of prefrontal astrocytes impairs cognition through the metabolic pathway of central kynurenines
静息态fMRI去噪流程在运动校正和行为预测中的有效性。	Pavlovich, K.	PDF	N/A	The efficacy of resting-state fMRI denoising pipelines for motion correction and behavioural prediction.
解码支持层次任务泛化的任务表示	Lee, W.	PDF	N/A	Decoding task representations that support generalization in hierarchical task
不同强度单侧手握疲劳对双侧运动的影响	Knorz, A. L.	PDF	N/A	The effects of varying intensities of unilateral handgrip fatigue on bilateral movement
早期生活压力暴露的相似性与成年早期神经表征的相似性相关	Ilomäki, M.	PDF	N/A	Similarity in Early Life Stress Exposure is Associated with Similarity in Neural Representations in Early Adulthood
自主运动在大脑大静脉中引起早期且远端的血流动力学下降	Eyre, B.	PDF	N/A	Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins
ARBEL：一种基于光学的图像分析机器学习工具，用于三维疼痛行为的自动分类	Barkai, O.	PDF	N/A	ARBEL: A Machine Learning Tool with Light-Based Image Analysis for Automatic Classification of 3D Pain Behaviors
VGCC辅助亚基α2δ1是一种与细胞外GluA1相互作用的蛋白质，并调节长时程增强（LTP）、空间记忆和癫痫易感性。	Leana-Sandoval, G.	PDF	N/A	The VGCC auxiliary subunit α2δ1 is an extracellular GluA1 interactor and regulates LTP, spatial memory, and seizure susceptibility
重复性脑熵（BEN）在沉思期间的改变	Lu, J.	PDF	N/A	Reproducible Brain Entropy (BEN) Alterations During Rumination
纹状体星形胶质细胞影响多巴胺动态和行为状态转换	Lazaridis, I.	PDF	N/A	Striatal Astrocytes Influence Dopamine Dynamics and Behavioral State Transitions
人类在感知推断中使用了对听觉空间和时间不确定性的过度自信估计。	Hong, F.	PDF	N/A	Humans use overconfident estimates of auditory spatial and temporal uncertainty for perceptual inference
“多少才算足够？”——儿童自然fMRI功能连接可靠性的考量	Rai, S. S.	PDF	N/A	How much is 'enough'? Considerations for functional connectivity reliability in pediatric naturalistic fMRI
早期生活逆境改变成年期腹侧被盖区神经元：对压力增加和强迫行为易感性的神经机制的启示	Gugula, A.	PDF	N/A	Early-life adversity alters adult nucleus incertus neurons: implications for neuronal mechanisms of increased stress and compulsive behavior vulnerability
RIG-I介导的神经元特异性I型干扰素信号在FUS-ALS中诱导神经退行性变，并为（FUS-）ALS提供了新的生物标志物驱动的个性化治疗选择。	Naumann, M.	PDF	N/A	RIG-I mediated neuron-specific IFN type 1 signaling in FUS-ALS induces neurodegeneration and offers new biomarker-driven individualized treatment options for (FUS-)ALS
KIF3C在调控小脑发育过程中Bergmann胶质细胞密度和模式形成中发挥作用	Waas, B.	PDF	N/A	KIF3C Regulates Bergmann Glia Density and Patterning during Cerebellar Development
由于产前大麻二酚暴露导致的焦虑发展轨迹的性别特异性破坏	Iezzi, D.	PDF	N/A	Sex-specific disruptions in the developmental trajectory of anxiety due to prenatal cannabidiol exposure
人类听觉大脑中时间整合的信号：心理洞察、脑电图证据及临床应用	Xu, H.	PDF	N/A	A signal of temporal integration in the human auditory brain: psychological insights, EEG evidence, and clinical application
人类听觉大脑中的时间整合信号：心理学洞察、脑电图证据及临床应用	Xu, H.	PDF	N/A	A signal of temporal integration in the human auditory brain: psychological insights, EEG evidence, and clinical application
KlebPhaCol：一个由社区驱动的克雷伯氏菌研究资源发现了一种与人类肠道相关的新型肠道噬菌体目。	Rothschild-Rodriguez, D.	PDF	N/A	KlebPhaCol: A community-driven resource for Klebsiella research identified a novel gut phage order associated with the human gut
利用孕早期阴道微生物群早期预测子痫前期	Kindschuh, W. F.	PDF	N/A	Early prediction of preeclampsia using the first trimester vaginal microbiome
在丝状蓝藻中，氰外排酶B对于运动性、生物膜形成和藻青素生产是必不可少的。	Parrett, G.	PDF	N/A	Cyanoexosortase B is essential for motility, biofilm formation and scytonemin production in a filamentous cyanobacterium
绘制犬类微生物组图谱：来自狗衰老项目的见解	Bamberger, T.	PDF	N/A	Mapping the canine microbiome: Insights from the Dog Aging Project
小鼠长期肠道衣原体定植期间肠道屏障破坏的洞察：单细胞转录组学方法	Tian, Q.	PDF	N/A	Insights into Intestinal Barrier Disruption During Long-Term Gut Chlamydia Colonization in Mice: A Single-Cell Transcriptomic Approach
研究辣椒素在通过细胞外囊泡促进柯萨奇病毒B3传播中的潜在作用	Chatterjee, S.	PDF	N/A	Investigating the potential role of capsaicin in facilitating the spread of coxsackievirus B3 via extracellular vesicles
沿海植物的根系有助于稳定海洋藻类固定的碳。	Hellige, I.	PDF	N/A	Roots of coastal plants stabilize carbon fixed by marine algae
识别基孔肯雅病毒nsP2 ATPase的抑制剂	Navarro, H.	PDF	N/A	Identification of Inhibitors of Chikungunya virus nsP2 ATPase
整合应激反应沉默的分子基础	Yang, Z.	PDF	N/A	The molecular basis of integrated stress response silencing
人类线粒体RNA聚合酶结构揭示转录起始位点和滑移机制	Shen, J.	PDF	N/A	Human mitochondrial RNA polymerase structures reveal transcription start-site and slippage mechanism
转录因子GATA1识别RNA的独特机制	Ugay, D. A.	PDF	N/A	A distinct mechanism of RNA recognition by the transcription factor GATA1
先进的肽纳米颗粒能够实现对多种细胞类型进行强大且高效的基因编辑器递送。	Gustafsson, O.	PDF	N/A	Advanced Peptide Nanoparticles Enable Robust and Efficient delivery of gene editors across cell types
SARS-CoV-2 N蛋白的动态集合揭示了头对头卷曲螺旋驱动的寡聚化和相分离现象	Hernandez, G. G.	PDF	N/A	Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation
靶向内质网应激和亚硝基氧化还原失衡在神经内分泌前列腺癌中的治疗作用：一氧化氮的作用	FIRDAUS, F.	PDF	N/A	Targeting Endoplasmic Reticulum Stress and Nitroso-Redox Imbalance in Neuroendocrine Prostate Cancer: The Therapeutic Role of Nitric Oxide
发散思维和创造性人格对多米尼加大学科学产出和创新质量的影响	Montano Medina, G. A.	PDF	N/A	The Influence of Divergent Thinking and Creative Personality on the Quality of Scientific Production and Innovation in a Dominican University
通过纳米孔测序和引导学习实现非天然碱基的直接高通量解卷积	Perez, M.	PDF	N/A	Direct high-throughput deconvolution of unnatural bases via nanopore sequencing and bootstrapped learning
使用Orbitrap Ascend Tribrid质谱仪对亲和纯化蛋白复合物进行FAIMS分析	Goswami, P.	PDF	N/A	Analysis of FAIMS for the Study of Affinity-Purified Protein Complexes Using the Orbitrap Ascend Tribrid Mass Spectrometer
环境暴露和家族背景会改变SARS-CoV-2感染后神经病理学和炎症的诱发。	Chatterjee, D.	PDF	N/A	Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection.
L-天冬酰胺酶治疗在T细胞依赖的B细胞激活模型中，对非恶性B细胞产生可逆的免疫调节和免疫抑制效应。	Hadzic, A.	PDF	N/A	L-Asparaginase treatment induces reversible immunoregulatory and immunosuppressive effects in non-malignant B cells in a model of T-cell dependent B cell activation
根据临床表型分层的系统性硬化症患者循环浆细胞样树突状细胞的独特代谢特征	Ferreira, B. H.	PDF	N/A	Distinct metabolic profiles of circulating plasmacytoid dendritic cells in systemic sclerosis patients stratified by clinical phenotypes
土壤细菌中性脂质脂肪酸：碳储存还是腐殖质标记？	Gorka, S.	PDF	N/A	Soil bacterial neutral lipid fatty acids: Markers for carbon storage or necromass?
扩展CarD相互作用网络：CrsL是耻垢分枝杆菌中的一种新型转录因子	Shoman, M.	PDF	N/A	Expanding the CarD interaction network: CrsL is a novel transcription factor in Mycobacterium smegmatis
全基因组测序揭示Enterobacter hormaechei为尼日利亚西南部六家三级护理医院的关键血流病原体。	Oni, F. I.	PDF	N/A	Whole genome Sequencing Reveals Enterobacter hormaechei as a key Bloodstream Pathogen in six tertiary care hospitals in southwestern Nigeria.
利用两种和三种物种的FliC嵌合体拯救细菌运动性	Scadden, J.	PDF	N/A	Rescue of bacterial motility using two and three-species FliC chimeras
利用两种和三种物种的FliC嵌合体拯救细菌运动性	Scadden, J.	PDF	N/A	Rescue of bacterial motility using two and three-species FliC chimeras
小龙虾病原菌Candidatus Paracoxiella cheracis n.g. n.sp.的完整基因组序列为我们深入了解其致病机制及Coxiellaceae科的系统发育关系提供了重要线索。	Ingle, D. J.	PDF	N/A	The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family
小龙虾病原菌Candidatus Paracoxiella cheracis n.g. n.sp.的完整基因组序列揭示了其致病机制及Coxiellaceae科的系统发育关系。	Ingle, D. J.	PDF	N/A	The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family
在铀污染的含水层中，微生物群落的多样性适度下降，组成变化显著	Fan, Y.	PDF	N/A	Modest functional diversity decline and pronounced composition shifts of microbial communities in a uranium-contaminated aquifer
金黄色葡萄球菌POT转运蛋白DtpT在人巨噬细胞内二/三肽摄取和谷胱甘肽利用中的独特作用	Khan, I.	PDF	N/A	Distinct roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages
针对TREM2-TYROBP跨膜结合的药物筛选	Cobas-Carreno, M.	PDF	N/A	Drug screening targeting TREM2-TYROBP transmembrane binding
更大的宿主影响和杂交性：入侵海藻宿主如何优于同时存在的本地物种	Ghotbi, M.	PDF	N/A	Greater host influence and promiscuity: How an invasive seaweed host has advantages over co-occurring natives
土地覆盖和气候变化对印度鸟类栖息地的影响	Diengdoh, V. L.	PDF	N/A	Impact of land cover and climate change on habitat of Indian birds
在波动环境中可塑性和性状置换的演变	Chevin, L.-M.	PDF	N/A	Evolution of plasticity and character displacement in a fluctuating environment
四倍体黑莓刺的遗传控制	Johns, C. A.	PDF	N/A	Genetic Control of Prickles in Tetraploid Blackberry
GAGER：基因调控网络辅助基因表达恢复	Chowdhury, M. Z. U. S.	PDF	N/A	GAGER: gene regulatory network assisted gene expression restoration
人β细胞中甘氨酸受体活性的分子相关性	Gomes, A. S.	PDF	N/A	Molecular Correlates of Glycine Receptor Activity in Human β Cells
人类诱导多能干细胞（iPSCs）中染色体12三体性激增的起源	Narozna, M.	PDF	N/A	Origin of Chromosome 12 Trisomy Surge in Human Induced Pluripotent Stem Cells (iPSCs)
热诱导的磷脂酰丝氨酸变化驱动HSPA1A在质膜的定位	Low, J.	PDF	N/A	Heat-Induced Phosphatidylserine Changes Drive HSPA1A's Plasma Membrane Localization
葡萄糖-6-磷酸酶对于果蝇精子的能量代谢、运动能力及生育力是必需的。	Hedjazi, S.	PDF	N/A	Glucose-6-phosphatase is required for sperm energy metabolism, motility and fertility in Drosophila
三维hiPSC-心脏微组织工业化用于高通量心脏安全性和药物发现筛选	de Korte, T.	PDF	N/A	Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening
成人口腔的免疫调节结构	Fernandes Matuck, B.	PDF	N/A	The Immunoregulatory Architecture of the Adult Oral Cavity
Retromer对抗阿片类药物引起的μ阿片受体下调	Dagunts, A.	PDF	N/A	Retromer Opposes Opioid-Induced Downregulation of the Mu Opioid Receptor
多梳抑制复合物2促进动脉粥样硬化斑块的脆弱性	Joshi, D.	PDF	N/A	Polycomb Repressive Complex 2 promotes atherosclerotic plaque vulnerability
沿着和逆着受限的粘附梯度进行单细胞迁移	Fortunato, I. C.	PDF	N/A	Single cell migration along and against confined haptotactic gradients
光遗传学诱导的微管乙酰化揭示了定向细胞迁移中肌动蛋白-微管交叉对话的分子动力学	Deb Roy, A.	PDF	N/A	Optogenetically Induced Microtubule Acetylation Unveils the Molecular Dynamics of Actin-Microtubule Crosstalk in Directed Cell Migration
通过mRNA定位控制上皮组织结构	Mason, D. E.	PDF	N/A	Control of Epithelial Tissue Organization by mRNA Localization
BECLIN-1 通过调节内吞运输、F-肌动蛋白组织和溶酶体功能，对维持胃肠道上皮完整性至关重要。	Juliani, J.	PDF	N/A	BECLIN-1 is Essential for the Maintenance of Gastrointestinal Epithelial Integrity by Regulating Endocytic Trafficking, F-actin Organization and Lysosomal Function
Erk1/2对Pak1的磷酸化作用于细胞迁移需要Arl4D作为支架蛋白的参与。	Chang, T.-W.	PDF	N/A	The phosphorylation of Pak1 by Erk1/2 for cell migration requires Arl4D acting as a scaffolding protein
MAGI2的调控及其在足细胞病变诊断中的应用	Siegerist, F.	PDF	N/A	The Regulation of MAGI2 and its Diagnostic Application in Podocytopathies
秀丽隐杆线虫的huntingtin蛋白，即htt-1，在应激条件下能够促进强效的自噬诱导和生存。	Chung, C. H.	PDF	N/A	C. elegans huntingtin, htt-1, promotes robust autophagy induction and survival under stress conditions
# BioRxiv 2024-12-01 Papers

标题	作者	PDF链接	代码仓库	Title
惩罚风险任务：在小鼠进行目标导向行为时监测其焦虑状态	Parker, K. E.	PDF	N/A	Punishment Risk Task: Monitoring anxiogenic states during goal directed actions in mice
肿瘤相关巨噬细胞的抗原呈递促使肿瘤浸润T细胞从原始的耗竭状态转变为终末耗竭状态。	Waibl Polania, J.	PDF	N/A	Antigen presentation by tumor-associated macrophages drives tumor-infiltrating T cells from a progenitor exhaustion state to terminal exhaustion
diplo-locus：一个轻量级的工具包，用于在一般二倍体选择下进行时间序列遗传数据的推断和模拟	Cheng, X.	PDF	N/A	diplo-locus: A lightweight toolkit for inference and simulation of time-series genetic data under general diploid selection
映射人类特异性缺失的顺式和反式调控靶基因	Fair, T.	PDF	N/A	Mapping cis- and trans-regulatory target genes of human-specific deletions
不同扰动下转录变异性的遗传基础	Tsuru, S.	PDF	N/A	Genetic properties underlying transcriptional variability across different perturbations
雄性小鼠对口腔内辣椒素引发的先天喜好和厌恶反应	Han, Y.	PDF	N/A	Innate liking and disgust reactions elicited by intraoral capsaicin in male mice
雌二醇的细胞内滞留由乳腺癌细胞中的含GRAM结构域蛋白ASTER-B介导	Kim, H. B.	PDF	N/A	Intracellular Retention of Estradiol is Mediated by GRAM Domain Containing Protein ASTER-B in Breast Cancer Cells
全国范围内的鸟类生物多样性和迁徙声学监测	Bick, A.	PDF	N/A	National-scale acoustic monitoring of avian biodiversity and migration
生物分子凝聚体在相分离的质量守恒反应-扩散系统的实验与理论之间架起了桥梁。	Li, C.	PDF	N/A	Biomolecular condensates bridge experiment and theory of mass-conserving reaction-diffusion systems in phase separation
环状RNA与人类胎盘组织老化和死产中的DNA损伤有关	Arthurs, A. L.	PDF	N/A	Circular RNAs correlate with DNA damage in ageing human placental tissue and in stillbirth
基于人工智能的发现与低温电子显微镜结构阐明的一种KATP通道药物伴侣蛋白	Elsheikh, A.	PDF	N/A	AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone
通过HiCapR映射HIV-1 RNA结构、同源二聚体、长程相互作用及持久性域	Zhang, Y.	PDF	N/A	Mapping HIV-1 RNA Structure, Homodimers, Long-Range Interactions and persistent domains by HiCapR
神经肌肉骨骼建模揭示了感觉运动皮层中适应性学习的肌肉水平神经动力学	DeWolf, T.	PDF	N/A	Neuro-musculoskeletal modeling reveals muscle-level neural dynamics of adaptive learning in sensorimotor cortex
各向异性拉伸使多细胞水螅聚集体中的肌动纤维自组织产生偏倚	Bailles, A.	PDF	N/A	Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates
共享和独特的终身压力源特征及网络连接性预测青少年的焦虑和抑郁	Qu, Y.	PDF	N/A	Shared and unique lifetime stressor characteristics and network connectivity predict adolescent anxiety and depression
基于Transformer的生存结果预测方法	Mellors, T.	PDF	N/A	A Transformer-Based Approach to Survival Outcome Prediction
折叠稀释和稀释液体积对细菌培养中菌落形成单位估计的影响	Jain, M.	PDF	N/A	The impact of fold-dilution and diluent volume on the estimation of colony forming units in a bacterial culture
刺皮动物中顺式调控元件和染色质组织的深度保守揭示了动物基因组的祖先调控特征	Magri, M. S.	PDF	N/A	Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
肿瘤乳酸脱氢酶C（LDHC）在乳腺癌中的免疫调节作用	Naik, A.	PDF	N/A	Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
个性化治疗脑膜瘤：肿瘤类器官药物筛选揭示对HDAC1/2i帕比司他的治疗脆弱性	Jungwirth, G.	PDF	N/A	Personalized Medicine for Meningiomas: Drug Screening on Tumor Organoids Exposes Therapeutic Vulnerabilities to HDAC1/2i Panobinostat
DGKα和ζ缺乏导致调节性T细胞功能失调、不稳定及转化为致病性T滤泡辅助细胞，从而触发以IgG1为主的自身免疫反应。	Li, L.	PDF	N/A	DGKα and ζ Deficiency Causes Regulatory T-Cell Dysregulation, Destabilization, and Conversion to Pathogenic T-Follicular Helper Cells to Trigger IgG1-Predominant Autoimmunity
非洲慈鲷鱼肠道中适应性细胞进化的超多样性	Fages, A.	PDF	N/A	Adaptive cellular evolution in the intestinal tracts of hyperdiverse African cichlid fishes
性及应激依赖的基底外侧杏仁核至伏隔核皮质酮释放激素/GABA投射的可塑性，该投射介导奖赏行为	Taniguchi, L.	PDF	N/A	Sex-and Stress-Dependent Plasticity of a Corticotropin Releasing Hormone / GABA Projection from the Basolateral Amygdala to Nucleus Accumbens that Mediates Reward Behaviors
昼夜活动预测亚洲埋葬甲虫Nicrophorus nepalensis的繁殖物候	Chen, H.	PDF	N/A	Circadian Activity Predicts Breeding Phenology in the Asian Burying Beetle Nicrophorus nepalensis
可卡因和安非他明调节的转录本在外侧隔核中的厌食和焦虑作用	Shankhatheertha, A.	PDF	N/A	Anorectic and anxiogenic actions of cocaine- and amphetamine-regulated transcript in the lateral septum
连接梯度的个体独特性是由嵌入网络的复杂性和它们的分散性所驱动的。	Serhan, Y.	PDF	N/A	Individual uniqueness of connectivity gradients is driven by the complexity of the embedded networks and their dispersion
利用钙成像技术对单个神经元对不同任务相关行为状态的选择性进行稳健表征	Huang, H.	PDF	N/A	Robust characterization of selectivity of individual neurons to distinct task-relevant behavioral states using calcium imaging
一种用于自动化评估神经退行性疾病小鼠模型中区域性脑萎缩的工具	Moldenhauer, S.	PDF	N/A	A tool to automate assessment of regional brain atrophy in mouse models of neurodegenerative disease
与肌萎缩侧索硬化症（ALS）相关的共伴侣蛋白DNAJC7通过调节HSF1活性，介导了对蛋白质毒性应激的神经保护作用。	Fleming, A. C.	PDF	N/A	The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity
在知觉决策任务的学习初期，内部状态便开始显现。	Cuturela, L. I.	PDF	N/A	Internal states emerge early during learning of a perceptual decision-making task
戒断初期阻断下丘脑泌素受体1可预防可卡因觅药行为的潜伏，并使多巴胺传递恢复正常	Clark, P. J.	PDF	N/A	Hypocretin Receptor 1 Blockade Early in Abstinence Prevents Incubation of Cocaine Seeking and Normalizes Dopamine Transmission
MortX：一个用于小鼠皮质分割和配准的领域泛化基准	Iqbal, A.	PDF	N/A	MortX: A Domain Generalization Benchmark for Mouse Cortex Segmentation and Registration
改造Barnes迷宫用于STARR FIELD痴呆小鼠模型：一个为期4天的实验方案，探究学习速率、记忆保持和认知灵活性。	Bertolli, A.	PDF	N/A	Renovating the Barnes maze for mouse models of Dementia with STARR FIELD: A 4-day protocol that probes learning rate, retention and cognitive flexibility.
基因移动元件在体内介导细胞类型特异的基因组组织和径向基因移动	Lucas, T.	PDF	N/A	Gene mobility elements mediate cell type specific genome organization and radial gene movement in vivo
小鼠和大鼠尾部附器发育过程中Edar和Xedar的差异表达	Wisniewski, S. A.	PDF	N/A	Differential Expression of Edar and Xedar During Mouse and Rat Tail Appendage Development
时间不确定性对标志追踪行为的影响	Kaneko, R.	PDF	N/A	Impact of Temporal Uncertainty on Sign-tracking Behavior
反社会盲穴鱼（Astyanax mexicanus）社会行为的机制	Sekulovski, B.	PDF	N/A	Mechanisms of Social Behavior in the Anti-Social Blind Cavefish (Astyanax mexicanus)
优化镍钛诺导管的超短脉冲激光制备策略以用于血管介入手术	Song, Y.	PDF	N/A	Optimizing femtosecond laser fabricating strategy of Nitinol hypotube for vascular interventional surgery
大肠杆菌可溶性polyA聚合酶生产条件的优化	Oscorbin, I. P.	PDF	N/A	Optimization of conditions for production of soluble E. coli polyA-polymerase
ZBP1与ADAR Z-Alpha结构域的染色质相互作用图谱：基于ChIP-Seq的比较研究	Hamrick, D.	PDF	N/A	Mapping Chromatin Interactions of ZBP1 and ADAR Z-Alpha Domains: A ChIP-Seq Based Comparison
鉴定感染印度奶牛泰勒虫属中与布帕伐醌抗性相关的基因变异。	Musale, P.	PDF	N/A	Identification of genetic variation in genes linked to buparvaquone resistance in Theileria sp infecting dairy cattle in India.
使用片段连接排他性甲基化测序（FLEXseq）富集低输入和片段化DNA的甲基化组	Yu, J.	PDF	N/A	Enriched Methylomes of Low-input and Fragmented DNA Using Fragment Ligation EXclusive Methylation Sequencing (FLEXseq)
在真核生物蛋白质组中发现多种嵌合肽，为镶嵌翻译假说的实验验证奠定了基础	Cakir, U.	PDF	N/A	Discovery of diverse chimeric peptides in a eukaryotic proteome sets the stage for the experimental proof of the mosaic translation hypothesis
使用分子动力学模拟对修饰寡核苷酸进行热力学参数估计	Park, S. W.	PDF	N/A	Thermodynamic Parameter Estimation for Modified Oligonucleotides Using Molecular Dynamics Simulations
影响复合物I功能的mtDNA点突变m.10191T>C的发病机制是一个多因素过程，导致线粒体代谢重塑。	Ahmadi, Z. A.	PDF	N/A	Pathogenesis of mtDNA point mutation m.10191T>C affecting complex I function is a multifactorial process leading to metabolic remodeling of mitochondria
G-四链体拓扑结构决定了富含鸟嘌呤的生物活性寡核苷酸的功能结果	Kharel, P.	PDF	N/A	G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides
新型2-花生四烯酰甘油类似物诱导的两步细胞死亡及其在人乳腺癌细胞中受溶血磷脂酰肌醇调节的作用	Akimov, M. G.	PDF	N/A	The Two-Step Cell Death Induction by the New 2-Arachidonoyl Glycerol Analog and its Modulation by Lysophosphatidylino-sitol in Human Breast Cancer Cells
烟草中环肽的出现与消失揭示了植物代谢演化的动态与机制	Suh, E. M.	PDF	N/A	The emergence and loss of cyclic peptides in Nicotiana illuminate dynamics and mechanisms of plant metabolic evolution
通过无监督随机森林实现蛋白质构象表示的无偏学习	Sahil, M.	PDF	N/A	Unbiased learning of protein conformational representation via unsupervised random forest
通过靶向神经氨酸酶活性位点，人类抗体广泛保护流感病毒的结构基础：CDR H3中重复模体的应用	Jo, G.	PDF	N/A	Structural basis of broad protection against influenza virus by a human antibody targeting the neuraminidase active site via a recurring motif in CDR H3
节俭的B细胞受体体细胞超突变广义模型	Sung, K.	PDF	N/A	Thrifty wide-context models of B cell receptor somatic hypermutation
有机和无机氮的协同转化促进了土壤微生物的繁殖，并在融雪期间增加了氮的保留。	Sorensen, P.	PDF	N/A	Coordinated organic and inorganic nitrogen transformations fuel soil microbial blooms and increase nitrogen retention during snowmelt
CpoS四聚体的形成促进了沙眼衣原体感染期间Inc-Inc相互作用。	Tijerina, X.	PDF	N/A	Tetramer formation of CpoS facilitates Inc-Inc interactions during Chlamydia trachomatis infection
评估oxathiapiprolin作为治疗贝壳杉枯死病潜在药物的植物内效力	Robinson, H. F.	PDF	N/A	Assessing the in planta efficacy of oxathiapiprolin as a potential treatment for kauri dieback disease
miRNAs在调节Nrf1和Nrf2在肝细胞癌上皮-间质转化中不同作用的关键机制	Chen, J.	PDF	N/A	The mechanisms by which miRNAs critically contribute to differential roles of Nrf1 and Nrf2 in modulating the epithelial-mesenchymal transformation of hepatocellular carcinoma
NuMA机械性地独立于其伙伴动力蛋白（dynein）强化纺锤体。	Cho, N. H.	PDF	N/A	NuMA mechanically reinforces the spindle independently of its partner dynein
高质量的中国白松露基因组和新颖的基于化石校准的盘菌纲分歧估计揭示了真松露基因组进化的速度和模式	Martelossi, J.	PDF	N/A	The high quality Chinese white truffle genome and novel fossil-calibrated estimate of Pezizomycetes divergence reveal the tempo and mode of true truffles genome evolution
CRISPRa介导的与遗传性视网膜营养不良相关的基因在急性分离的人类细胞中的激活，用于诊断目的	Weber, V. J.	PDF	N/A	CRISPRa-mediated activation of genes associated with inherited retinal dystrophies in acutely isolated human cells for diagnostic purposes
TEAL-seq：目标表达分析测序	Doing, G.	PDF	N/A	TEAL-seq: Targeted Expression Analysis Sequencing
利用深度神经网络全面枚举癌症干细胞样细胞的异质性	Chowdhury, D.	PDF	N/A	Comprehensive Enumeration of Cancer Stem-like Cell Heterogeneity Using Deep Neural Network
来自毛里求斯食蟹猕猴的多条全长纯合IGH单体型	Olubo, S.	PDF	N/A	Multiple full-length homozygous IGH haplotypes from Mauritian cynomolgus macaques
MultiPopPred：一种跨种族疾病风险预测方法，及其在南亚人群中的应用	Kamal, R.	PDF	N/A	MultiPopPred: A Trans-Ethnic Disease Risk Prediction Method, and its Application to the South Asian Population
长读长宏基因组样本中微生物污染读段的鉴定与缓解	Ayala Montano, S.	PDF	N/A	Identification and Mitigation of microbial contaminant reads from long-read metagenomic samples
通过重建亲代和子代链信息来纠正用于稀有等位基因检测的PCR衍生文库中的错误	Lim, H.	PDF	N/A	Correcting errors in PCR-derived libraries for rare allele detection by reconstructing parental and daughter strand information
HyperMPNN - 一种从嗜热菌中学习到的设计耐热蛋白质的通用策略	Ertelt, M.	PDF	N/A	HyperMPNN - A general strategy to design thermostable proteins learned from hyperthermophiles
利用基因组数据进行多类型种群轨迹的贝叶斯系统发育动力学推断	Vaughan, T. G.	PDF	N/A	Bayesian phylodynamic inference of multi-type population trajectories using genomic dat
靶向FAK和MEK的药物组合克服了胶质母细胞瘤的肿瘤异质性	Furqan, M.	PDF	N/A	Drug combinations targeting FAK and MEK overcomes tumour heterogeneity in glioblastoma
LNS8801：一种适合临床开发的G蛋白偶联雌激素受体的对映体纯激动剂	Natale, C. A.	PDF	N/A	LNS8801: An enantiomerically pure agonist of the G protein-coupled estrogen receptor suitable for clinical development
MUC5B启动子变异导致非纤维化肺中的蛋白质组变化	HERRERA, J. A.	PDF	N/A	The MUC5B promoter variant results in proteomic changes in the non-fibrotic lung
实施梭菌属鲁氏菌基因组规模模型以提升合成气发酵	Scott, W. T.	PDF	N/A	Implementation of a Clostridium luticellarii genome-scale model for upgrading syngas fermentations
# BioRxiv 2024-11-30 Papers

标题	作者	PDF链接	代码仓库	Title
影响单基因树年代测定准确性和精确性的因素	Louvel, G.	PDF	N/A	Factors influencing the accuracy and precision in dating single gene trees
解码LIPA风险位点与冠心病功能关系的变异体	Li, F.	PDF	N/A	Decoding the Variant-to-Function Relationship for LIPA, a Risk Locus for CAD
循环免疫细胞中的一种基因表达模块与免疫疾病期间的细胞迁移相关。	Sinha, D.	PDF	N/A	A gene-expression module in circulating immune cells is associated with cell migration during immune diseases.
学习塑造了前额叶皮层的神经几何结构	Wojcik, M. J.	PDF	N/A	Learning shapes neural geometry in the prefrontal cortex
解码人脑中观察到的行为背后的物理原理	Wurm, M. F.	PDF	N/A	Decoding the physics of observed actions in the human brain
健康微生物群——迈向功能性解读	Zielinska, K.	PDF	N/A	Healthy microbiome - moving towards functional interpretation
人类呼吸道中粘液纤毛清除的结构-功能关系	Roth, D.	PDF	N/A	Structure-function relationships of mucociliary clearance in the human airways
胰岛素淀粉样形态编码于氢键和静电相互作用，这些相互作用调控蛋白质相分离	Lenton, S. J.	PDF	N/A	Insulin Amyloid Morphology is Encoded in H-bonds and Electrostatics Interactions Ruling Protein Phase Separation
选择性上皮表达KRASG12D在Oncopig胰腺中驱动导管增生和纤维化	Jara, C. P.	PDF	N/A	Selective epithelial expression of KRASG12D drives ductal proliferation and desmoplasia in the Oncopig pancreas
vmTracking：虚拟标记克服多动物姿态追踪中的遮挡和拥挤问题	Azechi, H.	PDF	N/A	vmTracking: Virtual Markers Overcome Occlusion and Crowding in Multi-Animal Pose Tracking
对话中的情感内容和语义结构与前额叶皮层的人际神经同步性相关	Carollo, A.	PDF	N/A	Emotional Content and Semantic Structure of Dialogues Are Associated With Interpersonal Neural Synchrony in the Prefrontal Cortex
蛛形纲大脑的海洋起源揭示了螯肢亚门早期分化	Strausfeld, N. J.	PDF	N/A	Marine Origin of the Arachnid Brain Reveals Early Divergence of Chelicerata
预测病毒进化的概念和方法	Meijers, M.	PDF	N/A	Concepts and methods for predicting viral evolution
Srs2与PCNA的结合及其SUMO化作用在DNA损伤应答过程中有助于RPA的拮抗作用。	Fan, J.	PDF	N/A	Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response
启用微观现实大脑的电场模型	Qi, Z.	PDF	N/A	Enabling Electric Field Model of Microscopically Realistic Brain
线粒体钙信号调控纤维层状癌中的支链氨基酸分解代谢	Marsh, N. M.	PDF	N/A	Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
对白海扇（Eunicella singularis）毒液的蛋白质组和转录组特征的分析揭示了八放珊瑚类武器库的进化。	Modica, M. V.	PDF	N/A	The proteotranscriptomic characterization of venom in the white seafan Eunicella singularis elucidates the evolution of Octocorallia arsenal
房室结折返性心动过速在兔房室结模型中的发作、维持及自发性终止，受自主神经系统调控。	Ryzhii, M.	PDF	N/A	Atrioventricular nodal reentrant tachycardia onset,sustainability, and spontaneous termination in rabbit atrioventricular node model with autonomic nervous system control
传粉者对当地和景观草原特征的反应存在差异	Lichtenberg, E. M.	PDF	N/A	Pollinators differentially respond to local and landscape grassland features
在调节黑腹果蝇产卵决策中亲属关系和熟悉度相关社会信息的使用	Rakosy, E.	PDF	N/A	On the use of kinship and familiarity associated social information in mediating Drosophila melanogaster oviposition decisions
解耦冠状病毒Nsp1的功能角色	Baeumlin, E.	PDF	N/A	Uncoupling the functional roles of Coronavirus Nsp1
具有社会性抗生素抗性的细菌菌落的空间种群动态	Denk-Lobnig, M. K.	PDF	N/A	Spatial population dynamics of bacterial colonies with social antibiotic resistance
噬菌体介导的细菌群落间CRISPRi用于生物计算	Pujar, A.	PDF	N/A	Phage-mediated intercellular CRISPRi for biocomputation in bacterial consortia
使用饱和报告转座子突变技术进行全基因组范围内新基因的鉴定	Goodall, E. C. A.	PDF	N/A	Genome scale identification of new genes using saturated reporter transposon mutagenesis
伊塔克霉素生物合成需要两种脱氧核糖核酸酶来实现毒素自我抗性。	Dorival, J.	PDF	N/A	Yatakemycin biosynthesis requires two deoxyribonucleases for toxin self-resistance
具有触发阀的开敞式水渠系统中的毛细流动动力学	Tokihiro, J. C.	PDF	N/A	The dynamics of capillary flow in an open-channel system featuring trigger valves
溶剂动力学与蛋白质动力学的耦合有助于驱动表皮生长因子受体（EGFR/ErbB1/HER1）激酶域中外显子19缺失突变体的功能差异	Patil, K.	PDF	N/A	Coupled Solvent Dynamics and Protein Dynamics Help Drive Functional Differences in Exon-19 Deletion Mutants in the Epidermal Growth Factor Receptor (EGFR/ErbB1/HER1) Kinase Domain
铜绿假单胞菌中由RNase E支架结构域介导的关键功能和重要相互作用	Geslain, S. A. M.	PDF	N/A	Critical functions and key interactions mediated by the RNase E scaffolding domain in Pseudomonas aeruginosa
视觉对象优化头部方向编码	Siegenthaler, D.	PDF	N/A	Visual objects refine head direction coding
通过花粉间接从头再生法在药用型大麻（Cannabis sativa L.）中实现双单倍体发育。	Tonolo, F.	PDF	N/A	Double haploid development in drug-type Cannabis sativa L. through microspore indirect de-novo plant regeneration.
土壤真菌间细胞通讯多重筛选的合成平台	Schiesaro, G.	PDF	N/A	A synthetic platform for multiplex screening of cell-cell communication between soil fungi
使用动态聚焦通道数量可变的组合通道停用策略的成人耳蜗植入者的噪音中言语表现	Wohlbauer, D. M.	PDF	N/A	Speech in noise performance in adults with cochlear implants using a combined channel deactivation strategy with a variable number of dynamic focused channels
皮层生长抑素中间神经元对神经血管耦合的双向调控	Mohamed, B.	PDF	N/A	Bidirectional control of neurovascular coupling by cortical somatostatin interneurons
抗噬菌体防御中的淀粉样信号	Ibarlosa, L.	PDF	N/A	Amyloid signaling in antiphage defense
星形胶质细胞C3产物对tauopathy小鼠模型中神经元线粒体功能障碍的影响	Lei, C.	PDF	N/A	Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models
综合宏基因组学和血液生物标志物分析揭示了有氧和无氧干预在运动员和非运动员中引起的不同代谢反应	Zielinska, K.	PDF	N/A	Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals
不可通行边界生境中的家域溢出：原因、偏差及使用自相关核密度估计的校正	Hollins, J. P. W.	PDF	N/A	Home range spillover in habitats with impassable boundaries: Causes, biases, and corrections using autocorrelated kernel density estimation
使用BERT分词器建模引物-模板相互作用以预测PCR扩增的注意力-BiLSTM模型	Latifian, N.	PDF	N/A	Modeling Primer-Template Interactions using BERT Tokenizer to Predict PCR Amplification with Attention-BiLSTM
植物易感性的组织依赖性：通过根部和叶部对系统性植物病原菌拉氏假单胞菌（Ralstonia pseudosolanacearum）在茄子和番茄幼苗中的致病性比较研究	Bhuyan, S.	PDF	N/A	Tissue-dependent nature of plant susceptibility: a comparative pathogenicity study of the systemic phytopathogen Ralstonia pseudosolanacearum in eggplant and tomato seedlings through root and leaf
瞳孔大小变化揭示认知算术中的贝叶斯推理	Zenon, A.	PDF	N/A	Pupil size variations reveal Bayesian inference in cognitive arithmetic
对一个由宏基因组组装而成的基因组进行比较基因组分析，揭示了一种毛霉菌目（Mucoromycotina）细根内生菌根真菌中独特的共生特征	Cole, J.	PDF	N/A	Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus
使用一种新方法ARGO（红绿偏移分析），在体内可视化突触小泡蛋白突触蛋白/SNG-1的周转情况	Shiliaev, N.	PDF	N/A	Visualizing turnover of synaptic vesicle protein Synaptogyrin/SNG-1 in vivo using a new method, ARGO (Analysis of Red Green Offset)
与流量相关的叶片和根系性状的协调影响森林群落构建	Ma, Z.	PDF	N/A	Coordination of flux-related leaf and root traits impacts forest community assembly
揭示单一人皮肤部位共生棒状杆菌的多样性	Herman, R.	PDF	N/A	Revealing the diversity of commensal corynebacteria from a single human skin site
基准化浓度和直接提取方法用于废水监测八种人类呼吸道病毒：对快速应用于新型病原体的启示	Wang, A. L.	PDF	N/A	Benchmarking concentration and direct extraction methods for wastewater-based surveillance of eight human respiratory viruses: implications for rapid application to novel pathogens
伽马同步介导了图形-背景感知	Karimian, M.	PDF	N/A	Gamma Synchrony Mediates Figure-Ground Perception
不同的参考基因组会影响人口历史重建、选择扫描和群体遗传学总结统计的准确性。	Akopyan, M.	PDF	N/A	Divergent reference genomes compromise the reconstruction of demographic histories, selection scans, and population genetic summary statistics
谱系对特征的比较分析。	Anderson, S. A. S.	PDF	N/A	The comparative analysis of lineage-pair traits.
多种途径实现红色类胡萝卜素着色：家朱雀（Haemorhous mexicanus）不使用CYP2J19来产生红色羽毛	Koch, R. E.	PDF	N/A	Multiple pathways to red carotenoid coloration: House finches(Haemorhous mexicanus) do not use CYP2J19 to produce red plumage
趋同机制，策略各异：广食性与专食性蝙蝠物种花蜜摄入方式的比较	Quinche, L. L.	PDF	N/A	Convergent mechanisms, divergent strategies: a comparison of nectar intake between a generalist and a specialized bat species
高级人脑类器官作为研究胶质瘤干细胞与小胶质细胞及血管细胞相互作用及对放疗反应的模型	Raguin, J.	PDF	N/A	Advanced human cerebral organoids as a model for investigating glioma stem cell interactions with microglia and vascular cells and response to radiotherapy
腹侧嘴侧延髓（RVM）投射到外侧下丘脑区域（LHA），以驱动厌恶和焦虑。	Rani, M.	PDF	N/A	Rostral ventromedial medulla (RVM) projects to the lateral hypothalamic area (LHA) to drive aversion and anxiety
急性束缚应激和疼痛调节依赖于中脑导水管周围灰质与外侧隔核之间的相互作用。	Shah, D. P.	PDF	N/A	Acute restraint stress and pain modulation depend on the interaction between the periaqueductal gray and the lateral septum
增强的大脑-心脏连接作为治疗性虚拟现实沉浸后状态焦虑减少的前兆	Sezer, I.	PDF	N/A	Enhanced Brain-Heart Connectivity as a Precursor of Reduced State Anxiety After Therapeutic Virtual Reality Immersion
在非洲参与野味供应链的哺乳动物中检测到多种病毒	Geraerts, M.	PDF	N/A	A wide diversity of viruses detected in African mammals involved in the wild meat supply chain
NaDyNet：一个用于自然刺激动态网络分析的工具箱	Yang, J.	PDF	N/A	NaDyNet: A Toolbox for Dynamic Network Analysis of Naturalistic Stimuli
描述人类海马-皮层网络中电刺激引起的神经元和群体反应	van der Plas, M.	PDF	N/A	Characterizing neuronal and population responses to electrical stimulation in the human hippocampo-cortical network
CA2神经元在盐皮质激素受体敲除中的命运（或状态）。	Harris, E. P.	PDF	N/A	Fate (or state) of CA2 neurons in a mineralocorticoid receptor knockout.
4-甲基伞形酮（4-MU）通过改善学习和记忆障碍，对脑缺血/再灌注损伤具有神经保护作用。	Tamouk, S.	PDF	N/A	4-Methyllumbiferone (4-MU) exerts a neuroprotective effect against cerebral ischemia/reperfusion injury by ameliorating learning and memory impairments
体内网络活动的调节驱动了轴突始段处轴-轴突突触的纳米级重组织	Compans, B.	PDF	N/A	In vivo modulation of network activity drives the nanoscale reorganisation of axo-axonic synapses at the axon initial segment
剖析C端截短在调节aSyn病理形成和Lewy小体生物发生中的不同作用	Mahul-Mellier, A.-L.	PDF	N/A	Dissecting the differential role of C-terminal truncations in the regulation of aSyn pathology formation and the biogenesis of Lewy bodies
宜人的香气：通往舒缓自主反应和改善脑-体节律耦合的特权之门	Ghibaudo, V.	PDF	N/A	Pleasant smells: a privileged gateway to soothing autonomic responses and improving brain-body rhythm coupling
非平衡动力学作为微扰复杂性的起源	Stikvoort, W.	PDF	N/A	Nonequilibrium dynamics elicited as the origin of perturbative complexity
肠道菌群失调改变了急性癫痫负担及抗癫痫药物在Theiler病毒性脑炎模型中的活性	Erickson, I.	PDF	N/A	Intestinal Dysbiosis Alters Acute Seizure Burden and Antiseizure Medicine Activity in the Theiler's Virus Model of Encephalitis
在帕金森病中，从稳定位置开始迈步时，下肢的快速视觉运动反应得以保留。	Billen, L. S.	PDF	N/A	Lower-limb express visuomotor responses are spared in Parkinson's Disease during step initiation from a stable position
一种广谱锈菌中假定的效应因子基因组内变异推动了早期感染阶段	Degnan, R.	PDF	N/A	Intragenomic variants of a putative effector drive early-stage infection in a broad host-range rust fungus
心外膜分泌组特征及其功能评估：源自心外膜的细胞外囊泡与基质	Oliveira, C. C.	PDF	N/A	Characterization and Functional Assessment of Epicardial Secretome: Epicardium-Derived Extracellular Vesicles and Matrix
整体遗传条形码揭示了组织巨噬细胞发育的谱系树	Frank, L.	PDF	N/A	Holistic genetic barcoding reveals a lineage tree of tissue macrophage development
微外显子剪接调节因子srrm4的突变对斑马鱼神经发育的表型影响较小	Gupta, T.	PDF	N/A	Mutations in the microexon splicing regulator srrm4 have minor phenotypic effects on zebrafish neural development
评估气质对圈养红小鹿（Mazama americana）训练效率的影响	Gragnanello, L. C.	PDF	N/A	Assessing the impact of temperament on training efficiency in x-situ Red Brocket Deer (Mazama americana)
系统阻断多巴胺受体对大鼠双向主动回避获取的影响。	Vercammen, L.	PDF	N/A	The impact of systemic blockade of dopamine receptors on the acquisition of two-way active avoidance in rats.
恐惧泛化的增加导致消退泛化的减少	Lopez-Moraga, A.	PDF	N/A	Increased fear generalization results in reduced generalization of extinction
一种光学脑机接口揭示了后顶叶皮层在目标导向导航中的因果作用	Sorrell, E.	PDF	N/A	An optical brain-machine interface reveals a causal role of posterior parietal cortex in goal-directed navigation
将理想贝叶斯搜索器与神经网络模型结合用于混合搜索任务中的眼动预测	Ruarte, G.	PDF	N/A	Integrating Ideal Bayesian Searcher and Neural Networks Models for Eye Movement Prediction in a Hybrid Search Task
无需配对高场扫描的儿童超低场MRI深度学习超分辨率	Briski, U.	PDF	N/A	Deep learning super-resolution of paediatric ultra-low-field MRI without paired high-field scans
计算约束在猕猴V4拓扑图功能域出现中的作用	Jiang, D.	PDF	N/A	Computational constraints underlying theemergence of functional domains in thetopological map of Macaque V4
通过RNA干扰同时靶向HIF1A和HIF2A的双重基因疗法减轻了两种AMD小鼠模型中的视网膜退化	Ebner, L. J. A.	PDF	N/A	Dual-acting gene therapy targeting HIF1A and HIF2A by RNA interference mitigates retinal degeneration in two mouse models of AMD
红色代表沉重：行动意图重新激活与任务相关的认知线索的表征	Lee, N.	PDF	N/A	Red means heavy: Action intentions reactivate representations of task-relevant cognitive cues
半自动导航用于高效定位电子断层扫描在体积相关光电子显微镜中的感兴趣区域	Konishi, K.	PDF	N/A	Semi-automated navigation for efficient targeting of electron tomography to regions of interest in volume correlative light and electron microscopy
小鼠上丘投射至下橄榄核神经元的解剖学和功能检查	David, D. L.	PDF	N/A	Anatomical and functional examination of superior colliculus projections to the inferior olivary neurons in mice
利用一种新型病毒工具探索CA3记忆细胞性质的早期变化	Cupolillo, D.	PDF	N/A	Early changes in the properties of CA3 engram cells explored with a novel viral tool
推断子采样神经系统中的全局指数	Conte, D.	PDF	N/A	Inferring global exponents in subsampled neural systems
视觉剥夺与视觉恢复中的灰质异常	Pedersini, C. A.	PDF	N/A	Gray matter abnormalities in sight deprivation and sight restoration
基于核的LFP估计在详细的大规模脉冲网络模型中的小鼠视觉皮层模型	Meneghetti, N.	PDF	N/A	Kernel-based LFP estimation in detailed large-scale spiking network model of mouse visual cortex
黑色素细胞和荧光白色素细胞协同作用，为阿拉伯鳉鱼（Aphanius dispar）胚胎提供紫外线光保护。	Alenize, M.	PDF	N/A	Melanophore and fluoroleucophore synergistically photo-protect the Arabian killifish, Aphanius dispar, embryo from ultraviolet light
低氧抑制蝾螈骨骼肌的去分化	Vdovin, G.	PDF	N/A	Hypoxia inhibits newt skeletal muscle dedifferentiation
神经证据表明存在与动作相关的体感预测	Moran, C.	PDF	N/A	Neural evidence for action-related somatosensory predictions
高效整合基因库至酵母胞质质粒	Pisera, A.	PDF	N/A	Ultra-Efficient Integration of Gene Libraries onto Yeast Cytosolic Plasmids
在人肾类器官中定义和控制轴向肾单位模式与合成Wnt分泌组织者	Fausto, C. C.	PDF	N/A	Defining and Controlling Axial Nephron Patterning in Human Kidney Organoids with Synthetic Wnt-Secreting Organizers
年龄是疟疾炎症反应的内在驱动因素	Loughland, J.	PDF	N/A	Age is an intrinsic driver of inflammatory responses to malaria
连接体外与体内洞察：一种针对多药耐药铜绿假单胞菌的有效噬菌体疗法的药代动力学-药效学模型	Cha, J. S.	PDF	N/A	Bridging in vitro and in vivo insights: A PKPD model for effective phage therapy against multidrug-resistant Pseudomonas aeruginosa
在病毒附着和进入过程中扮演双重角色，使得人巨细胞病毒的gHgLgO三聚体成为病毒感染力的核心因素。	Thiessen, L.	PDF	N/A	A dual role in virion attachment and entry makes the human cytomegalovirus gHgLgO trimer the central player in virion infectivity
黄病毒NS1引发的血管内皮功能障碍促进病毒扩散	Puerta-Guardo, H.	PDF	N/A	Flavivirus NS1-triggered endothelial dysfunction promotes virus dissemination
依赖于FAD的单加氧酶在链霉菌ambofaciens中对金霉素重氮基功能化的作用	Vicente, C. M.	PDF	N/A	Role of a FAD-dependent monooxygenase in diazo group functionalisation of kinamycin in Streptomyces ambofaciens
从拉曼光谱直接识别特征并实现单分生孢子物种水平上的植物病原体精准数据驱动分类	Xu, X.	PDF	N/A	Direct Feature Identification from Raman Spectra and Precise Data-driven Classification of Phytopathogens at Single Conidium-Species Level
基于OMV的脑膜炎球菌疫苗对N. gonorrhoeae的保护作用与跨物种定向的体液和细胞免疫反应有关。	Zhu, W.	PDF	N/A	Protection against N. gonorrhoeae induced by OMV-based Meningococcal Vaccines are associated with cross-species directed humoral and cellular immune responses
土壤中活性氧物种与氮循环的动态变化作为挥发性活性氮氧化物产生的机制	Purchase, M. L.	PDF	N/A	Dynamics of Reactive Oxygen Species and Nitrogen Cycling in Soils as a Mechanism for Volatile Reactive Nitrogen Oxide Production
细菌核糖体生物合成的进化灵活性	Amikura, K.	PDF	N/A	Evolutionary flexibility of ribosome biogenesis in bacteria
全基因组测绘揭示EB病毒诱导的基因组变异，识别MUC19在EB病毒潜伏期中的作用	Yu, J.	PDF	N/A	Genome-wide mapping of EBV-induced genomic variationsidentifies the role of MUC19 in EBV latency
人巨细胞病毒全病毒蛋白质组学揭示gpUL141是一种病毒颗粒成分，通过调节包膜糖蛋白组成以抵御体液免疫	Bentley, K.	PDF	N/A	Whole Virion Proteomics of HCMV Reveals that gpUL141 is a Virion Component that Regulates Envelope Glycoprotein Composition to Protect Against Humoral Immunity
流感病毒A诱导的内质网PI4P生成涉及ATG16L1，并促进病毒核糖核蛋白的释放	Alemany, C.	PDF	N/A	Influenza A virus-induced production of PI4P at the endoplasmic reticulum involves ATG16L1 and promotes the egress of viral ribonucleoproteins
适应四环素可抑制系统以调节新生隐球菌中必需基因的表达	Fu, C.	PDF	N/A	Adaptation of the tetracycline-repressible system for modulating the expression of essential genes in Cryptococcus neoformans
失调的RNA剪接导致酒精相关性肝病中的再生失败	Chembazhi, U. V.	PDF	N/A	Dysregulated RNA splicing induces regeneration failure in alcohol-associated liver disease
完整的信使RNA存在于人体血浆和尿液中，并且它们的纯化大分子隔室中。	Verwilt, J.	PDF	N/A	Intact messenger RNA exists in human blood plasma and urine, and their purified macromolecular compartments
高灵敏度逆转录环介导等温扩增技术用于检测和鉴定花生环斑病毒和番茄斑萎病毒	de Breuil, S.	PDF	N/A	Highly sensitive reverse transcription loop-mediated isothermal amplification for detecting and identifying groundnut ringspot and tomato spotted wilt orthotospoviruses
O-GlcNAc糖基化下调增强了依托泊苷诱导的HepG2人肝癌细胞中p53介导的凋亡	Lee, J.	PDF	N/A	Downregulation of O-GlcNAcylation enhances etoposide-induced p53-mediated apoptosis in HepG2 human liver cancer cells
序列组成决定凝聚相的混溶性	Pei, G.	PDF	N/A	Sequence Composition Dictates Condensate Miscibility
体外通过Sortase A介导的法尼基化Cdc42	Tschirpke, S.	PDF	N/A	Sortase A-mediated farnesylation of Cdc42 in vitro
通过利什曼原虫墨西哥变种嘌呤2'-脱氧核糖基转移酶活性位点工程实现阿拉伯糖苷核苷的高效合成	Cecchini, D. A.	PDF	N/A	Efficient synthesis of arabinosyl nucleosides via active site engineering of the Leishmania mexicana purine 2'-deoxyribosyltranferase
TTF2促进停滞的复制叉在有丝分裂中被排出	Can, G.	PDF	N/A	TTF2 promotes replisome eviction from stalled forks in mitosis
对疟原虫肌动蛋白解聚因子与磷脂酰肌醇相互作用的功能性见解	Lasiwa, D.	PDF	N/A	Functional insights into Plasmodium actin depolymerizing factor interactions with phosphoinositides
MnmE-MnmG复合物的冷冻电镜结构揭示了其巨大的构象变化，并为tRNA修饰机制提供了新的见解。	Maes, L.	PDF	N/A	Cryo-EM structures of the MnmE-MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
计算机辅助设计的Z域肽，具有增强的VEGF抑制作用	Geist, C.	PDF	N/A	Computer-guided design of Z domain peptides with improved inhibition of VEGF
RBR E3泛素连接酶HOIL-1能够在体外泛素化多种非蛋白质底物。	Wang, X.	PDF	N/A	The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-proteinaceous substrates in vitro
# BioRxiv 2024-11-29 Papers

标题	作者	PDF链接	代码仓库	Title
撤回：利用物理信息元神经表示实现生物动力学的高保真、可泛化光场重构	Yi, C.	PDF	N/A	WITHDRAWN: High-fidelity, generalizable light-field reconstruction of biological dynamics with physics-informed meta neural representation
芯片感染：一种用于研究脑膜炎奈瑟菌定植和血管损伤的体外人血管模型	Pinon, L.	PDF	N/A	Infection-on-Chip: an in vitro human vessel to study Neisseria meningitidis colonization and vascular damages
mbctools: 一个用户友好的宏条形码分析和跨平台管道，用于分析大量生物多样性中的多种扩增子测序数据	Barnabe, C.	PDF	N/A	mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms
挑战反向传播：皮质中目标学习的证据	Aceituno, P. V.	PDF	N/A	Challenging Backpropagation: Evidence for Target Learning in the Cortex
急性心理社会压力诱导的能量应激标志物GDF15	Huang, Q.	PDF	N/A	The Energetic Stress Marker GDF15 is Induced by Acute Psychosocial Stress
灵活的海马体对抽象边界的表征支持记忆引导的选择。	Esposito, M.	PDF	N/A	Flexible hippocampal representation of abstract boundaries supports memory-guided choice.
一项系统综述量化了负责病原体传播的库蠓属物种的宿主吸食模式	Fairbanks, E. L.	PDF	N/A	A systematic review quantifying host feeding patterns of Culicoides species responsible for pathogen transmission
子宫肌瘤和宫颈癌中DEK表达的上调作为潜在的预后因素	Janiak, A.	PDF	N/A	Upregulation of DEK Expression in Uterine Myomas and Cervical Cancer as a Potential Prognostic Factor
探索SNP过滤策略：严格核心与软核心的影响	Taouk, M. L.	PDF	N/A	Exploring SNP Filtering Strategies: The Influence of Strict vs Soft Core
多聚磷酸盐比DNA更有效地区分蛋白质构象系综，促进多样化的组装和成熟行为。	Goyal, S.	PDF	N/A	Polyphosphate Discriminates Protein Conformational Ensembles More Efficiently than DNA Promoting Diverse Assembly and Maturation Behaviors
撤回：miRBench：一个全面的微RNA结合位点预测训练和基准测试数据集	Sammut, S.	PDF	N/A	WITHDRAWN: miRBench: A Comprehensive microRNA Binding Site Prediction Training and Benchmarking Dataset
人工智能建模能否区分传感器和辅助NLR免疫受体之间的蛋白质结构差异？	Toghani, A.	PDF	N/A	Can AI modelling of protein structures distinguish between sensor and helper NLR immune receptors?
从辣木（Moringa oleifera）种子中提取的纯化几丁质结合蛋白对小鼠伊立替康诱导的肠道黏膜炎的治疗效果	Ferreira, K. Q.	PDF	N/A	Therapeutic effects of a purified chitin-binding protein from Moringa oleifera seeds on irinotecan-induced intestinal mucositis in mice
帕金森病影响快速视觉运动反应的上下文控制，但不影响其表达，该反应启动视觉引导的伸手动作：多重交互运动通路的证据及其对帕金森病运动症状的启示	Gilchrist, M.	PDF	N/A	Parkinson's Disease affects the contextual control, but not the expression, of a rapid visuomotor response that initiates visually-guided reaching: Evidence for multiple, interacting motor pathways and implications for motor symptoms in Parkinson's Disease
静息状态下的阿尔法反应性在帕金森病中降低，并与步态变异性相关。	Lirani-Silva, E.	PDF	N/A	Resting-state alpha reactivity is reduced in Parkinson disease and associated with gait variability
在自然音乐聆听过程中人类听觉皮层的多流预测	Robert, P.	PDF	N/A	Multi-stream predictions in human auditory cortex during natural music listening
利用深度学习从大脑结构预测内化问题	Vandewouw, M. M.	PDF	N/A	Using deep learning to predict internalizing problems from brain structure
失眠症患者静息态功能磁共振成像研究揭示脑动力学模型显示脑状态切换减少	Jespersen, K. V.	PDF	N/A	Modelling of brain dynamics reveals reduced switching between brain states in insomnia disorder - a resting state fMRI study
未知来源的自发性炎症的成年患者在免疫表现上部分类似于斯蒂尔病。	Veiga, R.	PDF	N/A	Adults patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still's disease
对伊拉克患者中鲍氏不动杆菌和索布雷菌医院感染的碳青霉烯酶编码基因的调查	Al-Ouqaili, M. T. S.	PDF	N/A	An investigation of carbapenemase-encoding genes in Burkholderia cepacia and Aeromonas sobria nosocomial infections among Iraqi patients
拮抗细菌对不同军团菌种的抑制作用存在差异	Cavallaro, A.	PDF	N/A	Variable inhibition of different Legionella species by antagonistic bacteria
大型建筑物饮用水系统中军团菌肺炎菌株的基因组分析，历时25年	Seth-Smith, H. M.	PDF	N/A	Genomic Analysis of Legionella pneumophila in the Drinking Water System of a Large Building over 25 Years
MuMu：一种用于基于液滴的同时单细胞核RNA测序和ATAC测序系统的样本多路复用协议	Li, Z.	PDF	N/A	MuMu: a sample multiplexing protocol for droplet-based simultaneous single nuclei RNA- and ATAC-seq systems
在预先使用硫芥子素结合物处理的树突状细胞中抑制NF-kappaB可诱导免疫耐受	Palomares, F.	PDF	N/A	NF-kappaB inhibition in dendritic cells pre-treated with sulforaphane-conjugates induces immunotolerance
针对白纹伊蚊的不相容昆虫技术的发展：引入野生核背景恢复了人工感染沃尔巴克氏菌雄蚊的表现	Lejarre, Q.	PDF	N/A	Development of the Incompatible Insect Technique targeting Aedes albopictus: introgression of a wild nuclear background restores the performance of males artificially infected with Wolbachia
液泡pH通过TORC1信号传导在酵母复制衰老过程中调节网格蛋白介导的内吞作用	Antenor, K. G.	PDF	N/A	Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during yeast replicative aging
成熟的簇细胞表型沿着肠道隐窝-绒毛轴在细胞因子诱导的簇细胞增生后依次表达。	des Amorie, J. R. B.	PDF	N/A	Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia
突触线粒体的生物能量特征	Faria-Pereira, A.	PDF	N/A	Bioenergetic signature of Synaptic mitochondria
GABRA1移码变异损害GABA_A受体蛋白稳态	Williams, M. P.	PDF	N/A	GABRA1 frameshift variants impair GABAA receptor proteostasis
动脉粥样易损血流激活SMAD-FOXO1驱动内皮间质转化及动脉粥样硬化	Knaus, P.	PDF	N/A	Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and Atherosclerosis
TFEB/HLH-30介导的成年早期神经元溶酶体容量扩展在衰老过程中保护秀丽隐杆线虫树突的维持	Zhong, R.	PDF	N/A	TFEB/HLH-30-mediated expansion of neuronal lysosomal capacity in early adulthood protects dendrite maintenance during aging in Caenorhabditis elegans
仿生多孔硅用于合理设计的联合疗法，以诱导免疫原性细胞死亡	Saarela, S.	PDF	N/A	Biomimetic porous silicon for rationally engineered combination therapy to induce immunogenic cell death
用于空间飞行基因表达谱分析的Perturb-Seq数据机器学习模型	Johnson, L. F.	PDF	N/A	A Machine Learning Model of Perturb-Seq Data for Use in Space Flight Gene Expression Profile Analysis
从综合AI和聚合物物理模型中得出的染色质结构	Schultz, E. R.	PDF	N/A	Chromatin Structures from Integrated AI and Polymer Physics Model
电荷筛选和疏水性驱动反射蛋白的逐步组装和液-液相分离	Gordon, R.	PDF	N/A	Charge screening and hydrophobicity drive progressive assembly and liquid-liquid phase separation of reflectin protein
含有糖脂的多分散寡层囊泡的小角和准弹性中子散射	Bange, L.	PDF	N/A	Small-angle and quasi-elastic neutron scattering from polydisperse oligolamellar vesicles containing glycolipids
智能三维超分辨率显微镜揭示了核仁中RNA支架的结构	Berrevoets, E. S.	PDF	N/A	Smart 3D super-resolution microscopy reveals the architecture of the RNA scaffold in a nuclear body
脂质纳米颗粒pH驱动相变的机理洞察	Trollmann, M. F.	PDF	N/A	Mechanistic Insight into pH-Driven Phase Transition of Lipid Nanoparticles
利用傅里叶叠层散射光显微技术解析脑、关节和肌肉组织的结构复杂性	van Staalduine, S. E.	PDF	N/A	Deciphering Structural Complexity of Brain, Joint, and Muscle Tissues Using Fourier Ptychographic Scattered Light Microscopy
遗传性痉挛性截瘫相关突变残基的结构和功能作用：从katanin螺旋到环状结构转变模拟中获得的见解	Kelly, M. S.	PDF	N/A	Structural and functional role of residues undergoing hereditary spastic paraplegias-linked mutations: insights from a simulation of the spiral to ring transition in katanin
对细菌外膜脂质稳态中重要的马达-定子复合物力传导机制的结构洞察	Yeow, J.	PDF	N/A	Structural insights into the force-transducing mechanism of a motor-stator complex important for bacterial outer membrane lipid homeostasis
解密Cav1中的Ca²⁺渗透与价态选择性：分子动力学模拟揭示三离子撞击机制	Xue, L.	PDF	N/A	Deciphering Ca2+ Permeation and Valence Selectivity in Cav1: Molecular Dynamics Simulations Reveal the Three-Ion Knock-on Mechanism
对动力蛋白-动力蛋白激活蛋白-NuMA复合物的激活和调控的结构和功能见解	Aslan, M.	PDF	N/A	Structural and functional insights into activation and regulation of the dynein-dynactin-NuMA complex
具有内在无序区域的转录因子设计原则	Ji, W.	PDF	N/A	Design principles of transcription factors with intrinsically disordered regions
多组学分析揭示了溶瘤性寨卡病毒感染儿童脑肿瘤细胞所引发的关键免疫原性特征	Sherwood, M.	PDF	N/A	Multiomics analysis reveals key immunogenic signatures induced by oncolytic Zika virus infection of paediatric brain tumour cells
空间通量平衡分析揭示了肾癌和结直肠癌的组织来源和空间依赖性代谢重编程	Maspero, D.	PDF	N/A	Spatial Flux Balance Analysis reveals tissue-of-origin and spatially dependent metabolic rewiring in renal and colorectal cancer
来自EIAV疫苗的环境因素通过减弱NLRP3与NEK7的相互作用，精细调控NLRP3的激活。	Guo, x.	PDF	N/A	Env from EIAV vaccine delicately regulates NLRP3 activation via attenuating NLRP3-NEK7 interaction
在恒河猴中针对HIV包膜糖蛋白的保守融合肽进行免疫聚焦	Pratap, P. P.	PDF	N/A	Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques
城市化与当地环境异质性对热带蛙类表型变异性的影响	Provete, D. B.	PDF	N/A	The effect of urbanization and local environmental heterogeneity on phenotypic variability in a tropical frog
全球的山路显著改变了当地土壤的微气候。	Lejeune, R.	PDF	N/A	Mountain roads across the globe significantly alter local soil microclimates
基因网络拓扑结构驱动基因表达的突变景观	Le Rouzic, A.	PDF	N/A	Gene network topology drives the mutational landscape of gene expression
人类转录因子在跨组织中的异构体转换提示了一种广泛存在的调控机制。	Sidorov, S.	PDF	N/A	Cross-tissue isoform switches by human transcription factors suggest a widespread regulatory mechanism
新型沙雷氏菌（Serratia sarumanii）菌株GBS19的农药降解能力及其基因组特征	Alatassi, G.	PDF	N/A	Pesticide degradation capacity of a novel strain belonging to Serratia sarumanii (GBS19) with its genomic profile
利用纳米孔的马达蛋白辅助糖链转移和测序	Gao, Z.	PDF	N/A	Motor protein-assisted glycan translocation and sequencing using nanopores
鉴定神经调节蛋白为SERCA2b调节蛋白样蛋白及其通过粗粒度模拟评估其聚集倾向。	Ben Mariem, O.	PDF	N/A	Identification of neuronatin as a SERCA2b regulin-like protein and assessment of its aggregation propensity via coarse grained simulations.
解码糖基转移酶-B酶中决定底物特异性的因素——来自机器学习模型的见解	Hennen, S.	PDF	N/A	Decoding substrate specificity determining factors in glycosyltransferase-B enzymes - Insights from machine learning models
利用系统免疫学方法连接免疫型和肠型	Affaticati, F.	PDF	N/A	Bridging immunotypes and enterotypes using a systems immunology approach
肠道微生物群中细菌丰度的时间波动生态尺度取决于个体微生物物种和细菌群落的功能特性	Su, P.	PDF	N/A	Ecological Scaling of Temporal Fluctuations with Bacterial Abundance in Gut Microbiota Depends on Functional Properties of Individual Microbial Species and Bacterial Communities
对八种人类呼吸道病毒的污水监测：浓度法与直接提取法的基准测试及其对新型病原体快速应用的启示	Jiang, M.	PDF	N/A	Benchmarking concentration and direct extraction methods for wastewater-based surveillance of eight human respiratory viruses: implications for rapid application to novel pathogens
血浆蛋白酶-哌喹悖论持续存在	Walsh, B.	PDF	N/A	The Plasmepsin-Piperaquine Paradox Persists
在热应激期间小鼠胚胎干细胞中RNA聚合酶III转录的动态调节	Nguyen, T. F.	PDF	N/A	Dynamic regulation of RNA Polymerase III transcription in mouse embryonic stem cells during heat shock stress
AEGIS：基于个体的生命史进化模型	Bagic, M.	PDF	N/A	AEGIS: individual-based modeling of life history evolution
通过自然转化在人类肠道微生物组中测量微生物群落范围内的抗生素抗性传播	Chowdhury, N. N.	PDF	N/A	Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome
使用对称多项逻辑回归增强单核苷酸多态性基因分型	Nielsen, M. B.	PDF	N/A	Enhanced SNP Genotyping with Symmetric Multinomial Logistic Regression
使用DNBSEQ全基因组测序进行结构变异检测的性能评估	Rao, J.	PDF	N/A	Performance evaluation of structural variation detection using DNBSEQ whole-genome sequencing
对Lasius蚁属的基因组数据进行去污染，以实现准确的物种划分和杂交检测	Jecha, K.	PDF	N/A	Decontaminating genomic data for accurate species delineation and hybrid detection in the Lasius ant genus
来自Thermococcus onnurineus的热稳定CAS-Cas4对分支DNA的处理：扩展核酸酶活性的生化景观	Jain, M.	PDF	N/A	Branched DNA Processing by a Thermostable CAS-Cas4 from Thermococcus onnurineus: Expanding Biochemical Landscape of Nuclease Activity
基于mTurquoise2的葡萄糖生物传感器	Botman, D.	PDF	N/A	An mTurquoise2-based glucose biosensor
通过超解旋酶介导的等温扩增，实现了对高度重复或低复杂度序列DNA的可靠扩增。	Kang, J.	PDF	N/A	Reliable amplification of highly repetitive or low complexity sequence DNA enabled by superhelicase-mediated isothermal amplification
从头功能发现来自重组酶构建的大多样性单克隆T细胞库中的肽-MHC限制性CARs	Wang, Z.	PDF	N/A	De novo functional discovery of peptide-MHC restricted CARs from recombinase-constructed large-diversity monoclonal T cell libraries
用于RNA功能和结构预测的大规模基础模型	Zou, S.	PDF	N/A	A Large-Scale Foundation Model for RNA Function and Structure Prediction
嵌入式极值搜索：一种生物合成优化器	Smart, B. C.	PDF	N/A	Embedded Extremum Seeking: A Bio-synthetic Optimiser
利用自适应反馈控制工程细胞命运	Britto Bisso, F.	PDF	N/A	Engineering cell fate with adaptive feedback control
在CD4结合位点映射关键体细胞超突变有助于HIV-1疫苗设计	Dam, K.-M. A.	PDF	N/A	Mapping essential somatic hypermutations in a CD4-binding site bNAb informs HIV-1 vaccine design
Raver1将Ripk1 RNA剪接与caspase-8介导的焦亡细胞死亡、炎症及病原体抵抗联系起来	Zhang, B.	PDF	N/A	Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance
抗体反应的亲和力成熟是由不同浆细胞增殖介导的。	MacLean, A. J.	PDF	N/A	Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
从表型到受体：通过全面的受体分析验证大肠杆菌噬菌体的生理聚类	Kaneko, T.	PDF	N/A	From phenotype to receptor: validating physiological clustering of Escherichia coli phages through comprehensive receptor analysis
鉴定临床碳青霉烯酶、478种新型β-内酰胺酶以及从受污染的高北极峡湾沉积物中推测出的七个新的细菌门类。	Marathe, N. P.	PDF	N/A	Identification of clinical carbapenemases, 478 novel β-lactamases and putative seven new bacterial phyla from wastewater contaminated high arctic fjord sediments.
利用DeepCellMap这一结合深度学习和空间统计的深度学习方法，解析发育中人脑中微胶质细胞的空间组织结构。	Perochon, T.	PDF	N/A	Unraveling Microglial Spatial Organization in the Developing Human Brain with DeepCellMap, a Deep Learning Approach Coupled to Spatial Statistics
单细胞RNA测序显示，三刺鱼中没有减数分裂性染色体失活的现象。	Shaw, D.	PDF	N/A	Single cell RNA-sequencing reveals no evidence for meiotic sex chromosome inactivation in the threespine stickleback fish
一种药物分子伴侣稳定剂能够挽救G蛋白偶联受体中绝大多数致病变异体的表达。	Mighell, T.	PDF	N/A	A pharmacological chaperone stabilizer rescues the expression of the vast majority of pathogenic variants in a G protein-coupled receptor
增强多基因适应性检测：基于模拟进化与重测序数据的机器学习与统计方法比较研究	Caliendo, C.	PDF	N/A	Enhancing Detection of Polygenic Adaptation: A Comparative Study of Machine Learning and Statistical Approaches Using Simulated Evolve-and-Resequence Data
寄生蜂Nasonia vitripennis的发育性DNA甲基化	Thomas, C. L.	PDF	N/A	Developmental DNA Methylation in the Parasitoid Wasp Nasonia vitripennis
用于肺炎链球菌监测的可移植可扩展基因组分析流程：GPS流程	Hung, H. C. H.	PDF	N/A	A Portable and Scalable Genomic Analysis Pipeline for Streptococcus pneumoniae Surveillance: GPS Pipeline
CCA相关细菌对抗抗生素耐药性病原体的潜力：一项基因组调查	Lera-Lozano, D.	PDF	N/A	The Potential of CCA-associated Bacteria to Fight Antimicrobial-Resistant Pathogens: a Genomic Survey
抗原-葡聚糖聚合物的开发用于检测和评估CAR T细胞	Friis, R.	PDF	N/A	Development of antigen-dextramers for detection and evaluation of CAR T cells
药物抗性心脏重编程可缓解多柔比星诱导的小鼠和猪的心脏毒性	Zhang, Y.	PDF	N/A	Cardiac Reprogramming with Drug Resistance Alleviates Doxorubicin-induced Cardiotoxicity in Mice and Pigs
# BioRxiv 2024-11-28 Papers

标题	作者	PDF链接	代码仓库	Title
从局部相互作用和光滑梯度中涌现出强大的全局模块	Khona, M.	PDF	N/A	Emergence of robust global modules from local interactions and smooth gradients
KPop：通过序列嵌入实现微生物基因组的准确且可扩展的比较分析	Didelot, X.	PDF	N/A	KPop: Accurate and scalable comparative analysis of microbial genomes by sequence embeddings
在未受干扰的DNA复制过程中，ATR的激活受到VCP/p97的限制，这是通过从染色质中提取DNA聚合酶α/引发酶实现的。	Rodriguez-Acebes, S.	PDF	N/A	The activation of ATR during unperturbed DNA replication is restricted by VCP/p97 through the extraction of DNA polymerase α/Primase from chromatin
拟南芥LSM7对于生长素介导的SAUR基因调控和热形态发生是必不可少的。	Nardeli, S. M.	PDF	N/A	Arabidopsis thaliana LSM7 is essential for auxin-mediated regulation of SAUR genes and thermomorphogenesis
SMARCAD1和TOPBP1在从2C样状态向多能状态过渡时，对异染色质的维持起到了作用。	Sebastian-Perez, R.	PDF	N/A	SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state
全脑因果发现使用fMRI	Arab, F.	PDF	N/A	Whole-Brain Causal Discovery Using fMRI
尼古丁与安慰剂口香糖对疼痛敏感性的影响及其对峰值α频率的介导作用	Millard, S. K.	PDF	N/A	Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency
外侧嗅周皮质通过整合视觉空间序列来支持物体感知。	Bonnen, T.	PDF	N/A	Perirhinal cortex supports object perception by integrating over visuospatial sequences
RNA G-四链体在衰老和阿尔茨海默病中的新角色	Kallweit, L.	PDF	N/A	A New Role for RNA G-quadruplexes in Aging and Alzheimer's Disease
发声过程中对听觉反馈错误的意识和无意识感知：行为功能与事件相关电位相关性	Suchy, D.	PDF	N/A	Conscious and unconscious perception of errors in auditory feedback during vocalization: Behavioral functions and event-related potential correlates
母体蔗糖摄入改变了母亲、胎盘和胎儿的类固醇水平。	Seib, D. R.	PDF	N/A	Maternal sucrose consumption alters steroid levels in the mother, placenta, and fetus
海马体背腹轴上恐惧学习和恐惧表达的整合	Pompili, M. N.	PDF	N/A	Integration of fear learning and fear expression across the dorsoventral axis of the hippocampus
利用光遗传学技术绘制小鼠纹状体中与节律性相位相关的兴奋性图谱	Mohapatra, M.	PDF	N/A	Optogenetic mapping of rhythmic phase-dependent excitability in the mouse striatum
程序性细胞死亡与蚂蚁翅膀多态性的起源：对个体性重大进化转变的启示	Hanna, L.	PDF	N/A	Programmed cell death and the origin of wing polyphenism in ants: implications for major evolutionary transitions in individuality
MixtureFinder：用于系统发育分析的DNA混合模型估计	Ren, H.	PDF	N/A	MixtureFinder: Estimating DNA mixture models for phylogenetic analyses
VPS41的缺失会引发胰岛素储存的逐渐丧失以及β细胞身份的下调。	Yau, B.	PDF	N/A	VPS41 deletion triggers progressive loss of insulin stores and downregulation of beta-cell identity
肝脏特异性生存运动神经元（SMN）耗竭对中枢神经系统及外周组织病理学的影响	de Almeida, M. M.	PDF	N/A	Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology
Cdbgtricks：更新压缩de Bruijn图的策略	Hannoush, K.	PDF	N/A	Cdbgtricks: strategies to update a compacted de bruijn graph
群体认同促进大脑整合以实现集体表现	Enhui, X.	PDF	N/A	Group identification drives brain integration for collective performance
超高剂量率氦离子束：在保持肿瘤控制的同时最小化脑组织损伤	Dokic, I.	PDF	N/A	Ultra-High Dose Rate Helium Ion Beams: Minimizing Brain Tissue Damage while Preserving Tumor Control
未被抑制的皮层抑制性神经元集合控制着远距离记忆的提取	Wang, S.	PDF	N/A	Unsilenced inhibitory cortical ensemble gates remote memory retrieval
MLL4调控出生后腭部生长和中腭缝发育	Lee, J.-M.	PDF	N/A	MLL4 regulates postnatal palate growth and midpalatal suture development
一种基于脉冲依赖的突触神经网络片上学习算法	Stuck, M.	PDF	N/A	A Burst-Dependent Algorithm for Neuromorphic On-Chip Learning of Spiking Neural Networks
伏隔核中D1/D2中型多棘神经元在雄性东方田鼠配对结合形成中的不同作用	Zhang, L.	PDF	N/A	Different Roles of D1/D2 Medium Spiny Neurons in the Nucleus Accumbens in Pair Bond Formation of Male Mandarin Voles
铜绿假单胞菌中CsoR对趋化性和铜抗性的协同调控	He, M.	PDF	N/A	Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida
利用CRISPR富集的宏基因组方法增强废水样本中抗生素抗性基因的检测	Mao, Y.	PDF	N/A	Enhanced detection for antibiotic resistance genes in wastewater samples using CRISPR-enriched metagenomic method
磷酸化和去磷酸化在Rubisco活化酶调控中的作用	Bhatnagar, N.	PDF	N/A	The role of phosphorylation and dephosphorylation in the regulation of Rubisco activase
选择性自噬通过降解Su(var)2-10/PIAS来微调Stat92E活性，在果蝇神经胶质损伤信号传导过程中起作用。	Vincze, V.	PDF	N/A	Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signalling in Drosophila
广泛的行为指标与大脑微观结构之间的关联在自闭症谱系障碍（ASD）中普遍存在，这表明年龄可能介导了不同亚型的ASD。	Ressa, H.	PDF	N/A	Widespread Associations between Behavioral Metrics and Brain Microstructure in ASD Suggest Age Mediates Subtypes of ASD
Megabouts：一种用于斑马鱼运动分析的灵活管道	Jouary, A.	PDF	N/A	Megabouts: a flexible pipeline for zebrafish locomotion analysis
雌性生殖系特异性蛋白Sakura与Otu相互作用，对生殖干细胞的更新、分化及卵子发生过程至关重要。	Azlan, A.	PDF	N/A	Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis
工作记忆从优先和非优先状态中提取的长期影响	Born, F.	PDF	N/A	Long-Term Effects of Working Memory Retrieval From Prioritized and Deprioritized States
弓形虫引发的侵袭孔	Kegawa, Y.	PDF	N/A	The invasion pore induced by Toxoplasma gondii
鸡盲肠微生物群落的代谢建模揭示了竞争与合作的格局	Utkina, I.	PDF	N/A	Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation
利用H2在Cupriavidus necator H16中生产木糖醇	Jämsä, T.	PDF	N/A	H2-driven xylitol production in Cupriavidus necator H16
开发自主神经系统多尺度神经连接知识库	Imam, F. T.	PDF	N/A	Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System
核糖体生物合成超激活与ErbB信号传导介导的网络重塑导致对FGFR2抑制的适应性抗性	Zhang, T.	PDF	N/A	Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition
离子传感器与dSarm并行作用，促进神经退行性变	Avetisyan, A.	PDF	N/A	An Ionic Sensor acts in Parallel to dSarm to Promote Neurodegeneration
多尺度兴奋-抑制平衡动力学：整合代谢物动力学与时变执行网络	Saviola, F.	PDF	N/A	Multiscale excitation-inhibition balance dynamics: integrating metabolite kinetics with time-varying executive networks
核糖体丰度而非旁系同源基因组成对生殖系发育至关重要	Grobicki, K. Z. A.	PDF	N/A	Ribosome abundance, not paralogue composition, is essential for germline development
高分辨率成像图谱揭示了胰腺交感神经支配在糖尿病小鼠中的情境依赖性作用	Xu, Q.	PDF	N/A	High-resolution imaging atlas reveals context-dependent role of pancreatic sympathetic innervation in diabetic mice
靶向激活小胶质细胞PPARδ重编程免疫代谢并增强饮食诱导肥胖中的胰岛素敏感性。	Jiao, H.	PDF	N/A	Targeted activation of microglial PPARdelta reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity.
在问题解决过程中，眼睛和手的协同发音揭示了层次化的规划结构。	Eluchans, M.	PDF	N/A	Eye and hand coarticulation during problem solving reveals hierarchically organized planning
Lewy-MSA混合折叠驱动独特的神经元α-突触核蛋白病理	Enomoto, M.	PDF	N/A	Lewy-MSA hybrid fold drives distinct neuronal a-synuclein pathology
将空间药物异质性与微生物生长动力学在理论和实验中联系起来	Hu, Z.	PDF	N/A	Linking spatial drug heterogeneity to microbial growthdynamics in theory and experiment
在胚胎关键时期，线粒体活性氧的保守和HIF1-α信号传导指导随后的神经系统发育	Sobrid-Camean, D.	PDF	N/A	Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development
人类平滑受体中胆固醇感知与转运的能量学	Bansal, P. D.	PDF	N/A	Energetics of cholesterol perception and translocation in the human Smoothened receptor
有家族性额颞叶痴呆病史的无症状个体尿蛋白的变化	Su, Y.	PDF	N/A	Changes in urinary proteins of unaffected individuals with a family history of frontotemporal dementia
塑造发育中的小人：剥夺和补偿行为在感觉重映射中的作用	Tucciarelli, R.	PDF	N/A	Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping
发现一种源自SARS-CoV2 S2蛋白的肽段，具有类似超抗原的T细胞刺激特性	Tu, T. H.	PDF	N/A	The identification of a SARs-CoV2 S2 protein-derived peptide with super-antigen-like stimulatory properties on T-cells
特定谱系驱动因子库将果蝇腹神经索中发育中的神经回路与行为联系起来。	Soffers, J. H.	PDF	N/A	A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord.
对一个由宏基因组组装的基因组进行比较基因组分析，揭示了Mucoromycotina细根内生菌根真菌中独特的共生特性	Cole, J.	PDF	N/A	Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus
基于人群的元蛋白质组学揭示了肠道微生物群与表型之间的功能关联	Liang, S.	PDF	N/A	Population-based metaproteomics reveals functional associations between gut microbiota and phenotypes
通过瞬时递送CRISPR表观基因组编辑器核糖核蛋白实现可编程的表观基因组编辑	Xu, D.	PDF	N/A	Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins
氨基酸酰基-RNA环化连接的立体选择性	Kim, S.	PDF	N/A	Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation
基因（组）重复对GPCR信号通路扩展和进化的影响	Barradas, A.	PDF	N/A	Implications of gen(om)e duplications on the expansion and evolution of the GPCR signalling pathway
特定阶段CAR介导的信号传导从诱导多能干细胞生成类似初始状态、TCR缺失的CAR T细胞	Yoo, S. P.	PDF	N/A	Stage-specific CAR-mediated signaling generates naive-like, TCR-null CAR T cells from induced pluripotent stem cells
聚集肠道：神经退行与细菌功能性淀粉样蛋白之间的联系	Wojciechowska, A. W.	PDF	N/A	Aggregating gut: on the link between neurodegeneration and bacterial functional amyloids
SNMF：综合学习突变特征与预测DNA修复缺陷	Goossens, S. A. C. H.	PDF	N/A	SNMF: Integrated Learning of Mutational Signatures and Prediction of DNA Repair Deficiencies
TCF3::HLF通过调控增强子-启动子网络并激活MEF2C，促进白血病中未成熟造血干细胞基因表达	Priebe, V.	PDF	N/A	TCF3::HLF Orchestrates an Enhancer-Promoter Network with Activation of MEF2C to Promote Immature HSC gene Expression in Leukemia
分析公开可用的转录组数据以识别与骨肉瘤转移相关的关键基因和通路	Horak, I.	PDF	N/A	Analysis of publicly available transcriptomic data to identify key genes and pathways associated with osteosarcoma metastasis
Alk1在动脉内皮细胞中的缺失会导致鼻出血、脑微出血、动脉异常以及平滑肌覆盖缺陷。	Zhang, X.	PDF	N/A	Arterial endothelial deletion of Alk1 causes epistaxis and cerebral microhemorrhage with aberrant arteries and defective smooth muscle coverage.
大豆脉坏死病毒（SVNV）蛋白的特性分析：田间株系序列分析及不同细胞类型中定位模式的比较	Shehata, A. H.	PDF	N/A	Characterization of Soybean Vein Necrosis Virus (SVNV) Proteins: Sequence Analysis of Field Strains and Comparison of Localization Patterns in Differing Cell Types
感觉神经元中的Piezo2影响全身和脂肪组织的代谢	Passini, F. S.	PDF	N/A	Piezo2 in sensory neurons influences systemic and adipose tissue metabolism
蚕豆耐寒性的全基因组关联研究揭示了冷季豆科植物中的同源位点，并突出了相关的候选基因	Imbert, B.	PDF	N/A	Genome-wide association study of frost tolerance in Vicia faba reveals syntenic loci in cool-season legumes and highlights relevant candidate genes
PIEZO1在完整细胞中的纳米结构和结构多样性	Verkest, C.	PDF	N/A	Cluster nanoarchitecture and structural diversity of PIEZO1 in intact cells
使用蛋白酶体靶向纳米体偶联物降解内在无序蛋白	Sun, X.	PDF	N/A	Degradation of intrinsically disordered proteins using proteolysis targeting nanobody conjugate
自我冷却的花朵：炎热地中海环境中夏季开花的蓟的热生态学	Herrera, C. M.	PDF	N/A	Flowers that cool themselves: thermal ecology of summer-blooming thistles in hot Mediterranean environments
珊瑚修复只有在当地人类压力水平较低时才可行	Brookson, C. B.	PDF	N/A	Coral restoration is only practical when local human pressure levels are low
鱼与熊掌不可兼得：在景观连通性恢复中权衡生态系统服务与生物多样性组合	Neyret, M.	PDF	N/A	One cannot have it all: trading-off ecosystem services and biodiversity bundles in landscape connectivity restoration
与太平洋西北地区土壤中种植的优质冬豌豆品种相关的细菌群落	Yurgel, S.	PDF	N/A	Bacterial communities associated with food-quality winter pea cultivars grown in Pacific Northwest soils
进化救援模型提供了推动癌细胞种群走向灭绝的策略。	Dabi, A.	PDF	N/A	Evolutionary rescue model informs strategies for driving cancer cell populations to extinction
更新后的参考基因组序列和注释揭示了基因的丢失和获得，这些变化是裸鼹鼠生物学特性的基础。	Sokolowski, D. J.	PDF	N/A	An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology
siRNA途径对埃及伊蚊转座子表达的有限影响	Bergman, A.	PDF	N/A	Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti
关联分析揭示了在茄子驯化过程中，既有人为选择事件，也有环境选择事件。	Omondi, E.	PDF	N/A	Association analyses reveal both anthropic and environmental selective events during eggplant domestication
利用葡糖杆菌氧化菌对超镁铁质矿物的生物加速风化作用	Lee, J. J.	PDF	N/A	Bio-Accelerated Weathering of Ultramafic Minerals with Gluconobacter oxydans
长期肘部疼痛及重复经颅磁刺激对皮层抑制作用的影响：一项TMS-EEG研究	Chowdhury, N.	PDF	N/A	The effect of prolonged elbow pain and rTMS on cortical inhibition: A TMS-EEG study
鼠疫耶尔森菌的全球进化模式及其向非洲的传播	Mas Fiol, G.	PDF	N/A	Global evolutionary patterns of Yersinia pestis and its spread into Africa
宫颈阴道微生物特征可预测感染女性沙眼衣原体向生殖道上部的传播	Jeong, S.	PDF	N/A	Cervicovaginal microbial features predicts Chlamydia trachomatis spread to the upper genital tract of infected women
重复的香烟烟雾暴露会降低体外培养的人类肺成纤维细胞的增殖速率。	Cannard, E. C.	PDF	N/A	Repeated cigarette smoke exposure attenuates the proliferation rate of primary human lung fibroblasts in vitro
使用3D-NaissI方法揭示成年心脏组织的原生结构	PATALUCH, N.	PDF	N/A	Unveiling the native architecture of adult cardiac tissue using the 3D-NaissI method
Rab2B促进伴侣蛋白介导的肌动蛋白折叠，并防止锥虫中的发育性转录重编程和静止	Li, F.-J.	PDF	N/A	Rab2B promotes chaperonin-mediated actin folding and prevents developmental transcription reprogramming and quiescence in trypanosomes
非肌肉型α-肌动蛋白是心肌Z盘的内在组成部分，参与调节肌节周转、收缩力和心脏重塑过程。	Hayes, J. B.	PDF	N/A	A non-muscle α-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling
FIC-1介导的AMP化作用丧失会激活UPRER，并上调细胞质HSP70分子伴侣，以抑制多聚谷氨酰胺毒性。	Van Pelt, K. M.	PDF	N/A	Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity
喜马拉雅全基因组序列提供了对种群形成和适应的见解	Arciero, E.	PDF	N/A	Himalayan whole-genome sequences provide insight into population formation and adaptation
肝细胞癌阶段特异性转录组图谱：来自超级和差生存者的见解及预后特征鉴定	Xu, X.	PDF	N/A	Stage-Specific Transcriptome Landscape of Hepatocellular Carcinoma: Insights from Super and Poor Survivors with Prognostic Signature Identification
糖萼诱导的膜管形成	Xiao, K.	PDF	N/A	Glycocalyx-induced formation of membrane tubes
早期生活压力的性别二态结果背后的电路机制	Jiang, C.	PDF	N/A	Circuit mechanisms underlying sexually dimorphic outcomes of early life stress
基因组特征及多药耐药肺炎克雷伯菌株BCSIR-JUMIID的功能解析	Ahmed, M. F.	PDF	N/A	Genomic characterization and functional insights of multidrug-resistant Klebsiella pneumoniae strain BCSIR-JUMIID
Cavin1结合纳米抗体揭示了N端卷曲螺旋域的结构灵活性及其受调控的相互作用	Gao, Y.	PDF	N/A	Cavin1 binding nanobodies reveal structural flexibility and regulated interactions of the N-terminal coiled-coil domain
使用一种新方法ARGO（Analysis of Red Green Offset），在活体中可视化突触小泡蛋白Synaptogyrin/SNG-1的周转情况	Shiliaev, N.	PDF	N/A	Visualizing turnover of synaptic vesicle protein Synaptogyrin/SNG-1 in vivo using a new method, ARGO (Analysis of Red Green Offset)
由分布在膜表面的聚合酶驱动的肌动蛋白细丝组装	Mullins, D.	PDF	N/A	Actin filament assembly driven by distributive polymerases clustered on membrane surfaces
依那普利通过靶向抗氧化基因，经由磷酸化Smad1/5/9来缓解衰老。	Lyu, W.	PDF	N/A	Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9
永生化的肠间质细胞——体外干细胞龛	Canella, M.	PDF	N/A	Immortalized Intestinal Telocytes - A Stem Cell Niche In Vitro
Rho效应蛋白ARHGAP18通过YAP和Merlin协调Hippo通路的反馈回路，以调节细胞骨架和上皮细胞极性。	Murray, E. C.	PDF	N/A	The Rho effector ARHGAP18 coordinates a Hippo pathway feedback loop through YAP and Merlin to regulate the cytoskeleton and epithelial cell polarity.
CRL4DCAF12对MCMBP的调控确保了DNA复制的最佳许可	Yadav, A. K.	PDF	N/A	CRL4DCAF12 regulation of MCMBP ensures optimal licensing of DNA replication
Notch信号通路在腺体干细胞/祖细胞中驱动促再生和迁移特性	Cinat, D.	PDF	N/A	Notch Signaling Drives Pro-Regenerative and Migratory Traits in Glandular Stem/Progenitor Cells
内质网-线粒体接触结构组成的灵活性	Covill-Cooke, C.	PDF	N/A	Compositional Flexibility of the ER-Mitochondria Encounter Structure
微管聚合和动力蛋白的抑制会损害与室管膜瘤相关的ZFTA-RELA融合蛋白的核定位及NF-κB的激活。	Ishii, M.	PDF	N/A	Inhibition of microtubule polymerization and dynein impairs the nuclear localization of the ependymoma-associated ZFTA-RELA fusion protein and NF-κB activation
HelD是一种全球转录因子，能够增强快速生长的分枝杆菌中的基因表达。	Vankova, V.	PDF	N/A	HelD is a Global Transcription Factor Enhancing Gene Expression in Rapidly Growing Mycobacteria
通过邻近标记技术鉴定金黄色葡萄球菌与内皮细胞表面的相互作用组	Ruhling, M.	PDF	N/A	Identification of the Staphylococcus aureus Endothelial Cell Surface Interactome by Proximity Labeling
全球丰富滤食者对原绿球藻的捕食	Sweeney, C.	PDF	N/A	Prochlorococcus predation by a globally abundant filter feeder
细胞死亡效应下不可逆细胞分化的演变	Gao, Y.	PDF	N/A	The evolution of irreversible cell differentiation under cell death effect
泛素对SPRTN蛋白酶的变构激活维持了基因组的稳定性	Dürauer, S.	PDF	N/A	Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability
古HLA-B*73:01等位基因的分子特征揭示了其独特的肽展示谱及与KIR2DL2的偏倚性结合	Ross, P.	PDF	N/A	Molecular characterization of the archaic HLA-B*73:01 allele reveals presentation of a unique peptidome and skewed engagement by KIR2DL2
致癌性GNAQ/11诱导的IP3/钙信号通路重塑保护葡萄膜黑色素瘤免受钙驱动的细胞死亡	Garcia, C.	PDF	N/A	Oncogenic GNAQ/11-induced remodeling of the IP3/Calcium signaling pathway protects Uveal Melanoma against Calcium-driven cell death
MASLD驱动的骨丢失的性二态性	Goldscheitter, G. M.	PDF	N/A	Sexual dimorphism of MASLD-driven bone loss
成年斯普拉格-道利大鼠中，中脑动脉反应性和血流动力学的性别差异与全身动脉硬度的变化无关	Yamaleyeva, L.	PDF	N/A	Sex Differences in Middle Cerebral Artery Reactivity and Hemodynamics Independent from Changes in Systemic Arterial Stiffness in Adult Sprague-Dawley Rats
玉米光合性状变异的定量遗传学	Ali, W.	PDF	N/A	Quantitative genetics of photosynthetic trait variation in maize
通过图像到图像的翻译实现无标签多重显微成像，克服像素级和图像级相似性之间的权衡	Morikura, T.	PDF	N/A	Label-free multiplex microscopic imaging by image-to-image translation overcoming the trade-off between pixel- and image-level similarity
隐蔽的肌肉活动揭示了动态的冻结状态，并为动物的行动做好了准备。	Hobbiss, A. F.	PDF	N/A	Covert muscle activity reveals dynamic freezing states and prepares the animal for action
SMAC模拟物促使人类巨噬细胞吞噬活癌细胞	Liu, S. Y.	PDF	N/A	SMAC mimetics induce human macrophages to phagocytose live cancer cells
用于检测耐甲氧西林金黄色葡萄球菌光谱模式时间变化的非目标筛查方法及事后峰特征描述	Nichani, K.	PDF	N/A	Non-targeted screening method for detecting temporal shifts in spectral patterns of Methicillin Resistance Staphylococcus aureus and post-hoc description of peak features
景观中的农业实践对草原节肢动物有影响，此外还有当地条件和土地覆盖。	Brusse, T.	PDF	N/A	Farming practices in the landscape have an impact on grassland arthropods, in addition to local conditions and land cover
与流量相关的叶片和根系性状的协调影响森林群落构建	Ma, Z.	PDF	N/A	Coordination of flux-related leaf and root traits impacts forest community assembly
一种基于Omics的方法研究了拟南芥单个FERONIA和MARIS同源基因，证实了细胞壁完整性与脱落酸之间的联系。	Jobe, T. O.	PDF	N/A	An Omics approach on Marchantia polymorpha single FERONIA and MARIS homologs confirms links between cell wall integrity and abscisic acid
研究寄生植物中不同寄生水平下的长链非编码RNA	Rodrigues, W. F. C.	PDF	N/A	Investigating lncRNAs at different levels of parasitism in parasitic plants
炎症小体传感器NLRP3与REV7相互作用，通过同源重组维持基因组完整性。	Burlet, D.	PDF	N/A	The inflammasome sensor NLRP3 interacts with REV7 to maintain genome integrity through homologous recombination
Lamin B1依赖性调控人类有丝分裂分离酶	Picotto, J.	PDF	N/A	Lamin B1-dependent regulation of human separase in mitosis
利用电絮凝处理工艺对纺织印染废水进行处理和再加工	fatima, N.	PDF	N/A	Treatment and reprocessing of textile dyeing wastewater by using the electrocoagulation treatment process
环境DNA与社区科学：城市蜻蜓调查的优势与局限	Uche-Dike, R.	PDF	N/A	Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys
环境DNA与社区科学：城市蜻蜓调查的优势与局限	Uche-Dike, R.	PDF	N/A	Environmental DNA vs. Community Science: Strengths and Limitations for Urban Odonata Surveys
早期生活环境温度对野生鸟类肠道微生物群的影响？一项实验方法	Ruuskanen, S.	PDF	N/A	The effects of early-life ambient temperature on the gut microbiome of a wild bird? an experimental approach
pnetr：一个用于PnET系列森林生态系统模型的R包	Gao, X.	PDF	N/A	pnetr: An R package for the PnET family of forest ecosystem models
鼠李半乳糖醛酸聚糖-II二聚化缺陷损害了植物中生长与粘附维持之间的协调	Baba, A. I.	PDF	N/A	Rhamnogalacturonan-II dimerization deficiency impairs the coordination between growth and adhesion maintenance in plants
基于无人机的多光谱成像技术在洪涝耐受玉米品种识别中的应用：一个真实世界的案例研究	Mitchell, M. N.	PDF	N/A	Drone-Based Identification of Flood-Tolerant Maize via Multispectral Imaging: A Real-World Case Study
BPMs通过促进Aux/IAA蛋白IAA10的非生长素依赖性降解来调控拟南芥幼苗的发育。	Ban, Z.	PDF	N/A	BPMs regulate Arabidopsis seedling development by promoting auxin-independent degradation of the Aux/IAA protein IAA10
局部无序与工程光开关中增强的催化作用相关	McCormick, J. W.	PDF	N/A	Local disorder is associated with enhanced catalysis in an engineered photoswitch
背外侧前额叶皮层通过优化长期策略提取来驱动战略性放弃	Noel, J.-P. G.	PDF	N/A	Dorsolateral prefrontal cortex drives strategic aborting by optimizing long-run policy extraction
一种自动的、通用的错误信号在不同任务间共享，并预测不同感觉模态的置信度。	Davidson, M. J.	PDF	N/A	An automatic domain-general error signal is shared across tasks and predicts confidence in different sensory modalities
饥饿对雄性和雌性小鼠的趋避行为有不同的影响	Anversa, R. G.	PDF	N/A	Hunger alters approach-avoidance behaviours differently in male and female mice
评估利用磁共振成像（MRI）测量人脑中脑脊液（CSF）动力学全谱新方法的可行性：来自模拟研究的见解	van der Voort, E.	PDF	N/A	Assessing the feasibility of a new approach to measure the full spectrum of CSF dynamics within the human brain using MRI: insights from a simulation study
大黄蜂对氨基酸的味觉敏感性	Rossoni, S.	PDF	N/A	Gustatory sensitivity to amino acids in bumblebees
功能成熟与经验依赖性可塑性在成年新生嗅球多巴胺能神经元中	Tufo, C.	PDF	N/A	Functional maturation and experience-dependent plasticity in adult-born olfactory bulb dopaminergic neurons
赛洛西宾-NMDAR调节剂给药的协同行为与神经可塑性效应。	Ben Tal, T.	PDF	N/A	Synergistic Behavioral and Neuroplastic Effects of Psilocybin-NMDAR Modulator Administration.
胆碱能信号在多感官伽马刺激诱导的淀粉样蛋白周围血管清除中的作用	Lavoie, N. S.	PDF	N/A	The role of cholinergic signaling in multi-sensory gamma stimulation induced perivascular clearance of amyloid
通过综合应激反应感知胞外L-脯氨酸的可用性决定细胞竞争的结果。	Krishnan, S.	PDF	N/A	Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition.
草履虫的群集行为	Tabata, T.	PDF	N/A	The swarming behaviors of Vorticella
行动中规划：解决顺序实体任务中规划与行动的连续动态问题	Nuzzi, D.	PDF	N/A	Planning-while-acting: addressing the continuous dynamics of planning and action in a sequential embodied task
对未来的认知：海豚知道何时需要为未来记住某些事情。	Ortiz, S. T.	PDF	N/A	Awareness of the future: Dolphins know when they need to remember for the future
双向响应的温度感受器编码冷和暖	Bokiniec, P.	PDF	N/A	Bidirectionally responsive thermoreceptors encode cool and warm
正常衰老过程中脑血流量和葡萄糖代谢率在性别上的差异及其关联性。	Deery, H.	PDF	N/A	Sex differences in the rates and association of cerebral blood flow and glucose metabolism in normative ageing.
GABA与谷氨酰胺-谷氨酸动态的解耦及其在触觉感知中的作用：一项fMRS研究	Pasanta, D.	PDF	N/A	Decoupling of GABA and Glutamine-Glutamate Dynamics and their role in tactile perception: An fMRS Study
高维数据空间中或多或少存在潜在变量？这正是问题的关键所在。	Vaccari, F. E.	PDF	N/A	More or less latent variables in the high-dimensional data space? That is the question
海马CA2神经元不成比例地表达AAV递送的遗传物质	Alexander, G.	PDF	N/A	Hippocampal CA2 neurons disproportionately express AAV-delivered genetic cargo
兴奋性和抑制性细胞的层依赖比率如何塑造平衡网络中的皮层编码	Alizadeh, A.	PDF	N/A	How the layer-dependent ratio of excitatory to inhibitory cells shapes cortical coding in balanced networks
癫痫持续时间中的周期及其在破伤风毒素大鼠模型中的潜在动态	Zarei Eskikand, P.	PDF	N/A	Cycles in Seizure Duration and Their Underlying Dynamics in the Tetanus Toxin Rat Model
异甘草素减轻了链脲佐菌素诱导的阿尔茨海默病小鼠模型中的认知障碍、脑内tau蛋白磷酸化及氧化应激。	Tang, Z.	PDF	N/A	Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimers disease
st-DenseViT：一种用于动态脑网络密集预测的弱监督时空视觉Transformer	Kazemivash, B.	PDF	N/A	st-DenseViT: A Weakly Supervised Spatiotemporal Vision Transformer for Dense Prediction of Dynamic Brain Networks
静息态功能连接和快速纺锤波的时间组织有助于健康老化中的情景记忆巩固	Hamel, A.	PDF	N/A	Resting-state functional connectivity and fast spindle temporal organization contribute to episodic memory consolidation in healthy aging
光遗传学操控细胞核背侧蛋白揭示了转录的时间需求及后果	Pimmett, V. L.	PDF	N/A	Optogenetic manipulation of nuclear Dorsal reveals temporal requirements and consequences for transcription
P300/CBP催化的乙酰化通过激活DUX来保护次级合子基因组激活	Xiao, L.	PDF	N/A	p300/CBP-catalyzed acetylation safeguards minor zygotic genome activation via activating DUX
好斗的冲突会影响沙漠蚂蚁的归巢路径整合	Bollig, A.	PDF	N/A	Aggressive conflict impacts path integration in homing desert ants
一种用于生物分子凝聚物模拟的无序RNA粗粒度模型	Yasuda, I.	PDF	N/A	A coarse-grained model of disordered RNA for simulations of biomolecular condensates
通过多站点DMS探针在活细胞中同时映射RNA的二级、三级和四级结构	Saleem, I.	PDF	N/A	Simultaneous mapping of RNA secondary, tertiary, and quaternary structure in living cells by multi-site DMS probing
IL-33/ST2信号轴在急性SARS-CoV-2感染中的发病机制中起驱动作用	Fleming, C.	PDF	N/A	The IL-33/ST2 signaling axis drives pathogenesis in acute SARS-CoV-2 infection
在合成人类肠道微生物群落中发现替代稳定状态	Garza, D. R.	PDF	N/A	Discovery of alternative stable states in a synthetic human gut microbial community
广泛保守的新型色素产生在枯草芽孢杆菌物种中的特征描述	Stannius, R. O.	PDF	N/A	Characterization of widely conserved novel pigment production in Bacillus subtilis species
真核生物核糖体中药物结合残基的自然变异	Chan, L. I.	PDF	N/A	Natural variation of the drug-binding residues in eukaryotic ribosomes
衣原体对兼性宿主多细胞性的适应	Helmlinger, L.	PDF	N/A	The adaptation of chlamydiae to facultative host multicellularity
揭示单一人皮肤部位共生棒状杆菌的多样性	Thomas, G. H.	PDF	N/A	Revealing the diversity of commensal corynebacteria from a single human skin site
折叠稀释和稀释液体积对细菌培养中菌落形成单位估计的影响	Jain, M.	PDF	N/A	The impact of fold-dilution and diluent volume on the estimation of colony forming units in a bacterial culture
snRNA输出复合物协同组装的结构基础	Dubiez, E.	PDF	N/A	Structural basis for the synergistic assembly of the snRNA export complex
基因组中转换突变频率高于颠换突变的证据：基于密度泛函理论的碱基对结合能计算	Deka, N.	PDF	N/A	Higher frequency of transition mutation over transversion mutation in genomes: evidence from the binding energy calculation of base pairs using DFT
用于下一代测序应用的果蝇总RNA中高效去除核糖体RNA	Koppaka, O.	PDF	N/A	EFFICIENT RIBOSOMAL RNA DEPLETION FROM DROSOPHILA TOTAL RNA FOR NEXT-GENERATION SEQUENCING APPLICATIONS
piRNA通路介导了Aedes蚊子体细胞和生殖细胞中LTR逆转录转座子的转录沉默。	Taskopru, E.	PDF	N/A	The piRNA pathway mediates transcriptional silencing of LTR retrotransposons in the soma and germline of Aedes mosquitoes
遗传性出血性毛细血管扩张症动静脉畸形中PIEZO1的过度表达	Park, H.	PDF	N/A	PIEZO1 overexpression in hereditary hemorrhagic telangiectasia arteriovenous malformations
系统探索NOD样受体中的域组合，揭示了Sordariales真菌中两种类型的NACHT域	bonometti, l.	PDF	N/A	Systematic exploration of domain assortments in NOD-like receptors uncovers two types of NACHT domains in Sordariales fungi
人类多能干细胞系中转录基因调控的全基因组单细胞CRISPRi图谱	Feng, C.	PDF	N/A	A genome-scale single cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines
通过CRISPR/Cas9和多个重组腺相关病毒（rAAV）高效创建和表征多千碱基敲入	Sentmanat, M. F.	PDF	N/A	Efficient creation and characterization of multi-kilobase knockins by CRISPR/Cas9 and multiple rAAVs
达卡市内河流微生物群落的时间和空间分布	ALOM, M. M.	PDF	N/A	Temporal and spatial distribution of microbial community in urban river in Dhaka
基因组组织与CUT&Tag（GO-CaT）技术识别了发育中人脑神经元中与核膜相关域的亚结构及其成熟过程	Zhang, C.	PDF	N/A	Genome Organization with CUT and Tag (GO-CaT) identifies substructure and maturation of lamina-associated domains in neurons of the developing human brain
从头非分隔化微生物用于纳米抗体的定向进化	Wu, D.	PDF	N/A	De novo non-compartmentalized microorganism for directed evolution of nanobodies
一类依赖结合蛋白的溶质转运蛋白，以百日咳博德特氏菌中的TAXI-GltS系统为例	Jaques, L. M.	PDF	N/A	A new class of binding protein-dependent solute transporter exemplified by the TAXI-GltS system from Bordetella pertussis
细菌磷脂酰胆碱N-甲基转移酶合成磷脂酰胆碱的结构基础	Watanabe, Y.	PDF	N/A	Structural basis for phosphatidylcholine synthesis by bacterial phospholipid N-methyltransferases
结合糖苷酶与纳米孔技术进行糖链测序	Gao, Z.	PDF	N/A	Combining Glycosidases and Nanopore Technology for Glycan Sequencing
对秀丽隐杆线虫中随年龄变化的胞外囊泡蛋白的元分析	Bhunia, P. K.	PDF	N/A	A meta-analysis of age-dependent changes in extracellular vesicle proteins in C. elegans
一种具有广泛底物谱的LarA消旋酶的催化及底物特异性的结构基础	Gatreddi, S.	PDF	N/A	Structural Basis for Catalysis and Substrate Specificity of a LarA Racemase with a Broad Substrate Spectrum
肠道微生物群衍生的GlcNAc-MurNAc是一种TLR4激动剂，能够保护宿主肠道。	Li, C.	PDF	N/A	Gut microbiota-derived GlcNAc-MurNAc is a TLR4 agonist that protects the host gut
使用CRISPR-Cas12a实现读出的抗逆转录病毒药物快速酶学检测	Singh, M. A.	PDF	N/A	Rapid enzymatic assay for antiretroviral drug monitoring using CRISPR-Cas12a enabled readout
建模和测量密码子使用如何调节细菌中蛋白质过表达过程中负担与产量之间的关系	Roots, C. T.	PDF	N/A	Modeling and measuring how codon usage modulates the relationship between burden and yield during protein overexpression in bacteria
重新利用的STAT3抑制剂乙胺嘧啶可控制分枝杆菌感染引起的血管通透性和分枝杆菌负荷	Han, D. J.	PDF	N/A	The repurposed STAT3 inhibitor pyrimethamine controls mycobacterial infection-induced vascular permeability and mycobacterial burden
合作簇结合调控了烟曲霉铁调节因子HapX在铁饥饿、充足和过量条件下的功能转换，以适应这些不同的铁环境。	Oberegger, S.	PDF	N/A	Cooperative cluster-binding regulates the functional transitions of the Aspergillus fumigatus iron regulator HapX for adaptation to iron starvation, sufficiency and excess
双向互动对双人踝关节和腕关节追踪的影响	Short, M. R.	PDF	N/A	Effects of Uni- and Bidirectional Interaction During Dyadic Ankle and Wrist Tracking
NoButter：一个用于减少CosMx空间分子成像数据中转录本分散的R包	O'Hora, B.	PDF	N/A	NoButter: An R package for reducing transcript dis-persion in CosMx Spatial Molecular Imaging Data
OmniSegger：一种用于细菌细胞延时图像分析的管道	Lo, T. W.	PDF	N/A	OmniSegger: A time-lapse image analysis pipeline for bacterial cells
协同多重相互作用介导伴侣蛋白HtrA1对α-突触核蛋白聚集的有效抑制	Chinchilla, P.	PDF	N/A	Synergistic Multi-Pronged Interactions Mediate the Effective Inhibition of Alpha-Synuclein Aggregation by the Chaperone HtrA1
通过冷冻电子断层扫描技术揭示表皮生长因子受体在细胞外囊泡中的结构与组织	Gonzalez-Magaldi, M.	PDF	N/A	Structure and organization of full-length Epidermal Growth Factor Receptor in extracellular vesicles by cryo-electron tomography
D-葡萄糖醛酸C5-差向异构酶通过结合EGFR抑制肾脏纤维化	Jing, X.	PDF	N/A	D-glucuronyl C5-epimerase binds to EGFR to suppress kidney fibrosis
设计针对肽-MHC-I复合物的高特异性结合剂	Liu, B.	PDF	N/A	Design of high specificity binders for peptide-MHC-I complexes
氮素富集改变了根瘤菌基因的选择	Hill, C. A.	PDF	N/A	Nitrogen enrichment alters selection on rhizobial genes
用于骨软骨界面再生工程的具有受控矿物梯度水凝胶的高级生物打印	Zhao, X.	PDF	N/A	Advanced Bioprinting of Hydrogels with Controlled Mineral Gradients for Regenerative Engineering of the Osteochondral Interface
EasyPubPlot：一个用于快速组学数据探索和可视化的闪亮网络应用程序	Tien, N. T. N.	PDF	N/A	EasyPubPlot: a shiny web application for rapid omics data exploration and visualization
Brisk：精确的资源高效型k-mer字典	Smith, C.	PDF	N/A	Brisk: Exact resource-efficient dictionary for k-mers
分子动力学语言模型	Murtada, M. H.	PDF	N/A	Language Models for Molecular Dynamics
加速全基因组比对在全基因组组装时代的重要性	Chandra, G.	PDF	N/A	Accelerating whole-genome alignment in the age of complete genome assemblies
CASTER-DTA：用于预测药物-靶点亲和力的等变图神经网络	Kumar, R.	PDF	N/A	CASTER-DTA: Equivariant Graph Neural Networks for Predicting Drug-Target Affinity
FIDDLE：一种从串联质谱预测化学公式的深度学习方法	Hong, Y.	PDF	N/A	FIDDLE: a deep learning method for chemical formulas prediction from tandem mass spectra
G蛋白抑制剂YM-254890是一种别构粘合剂。	Trent, T.	PDF	N/A	The G protein inhibitor YM-254890 is an allosteric glue
一个注释详尽的三阴性乳腺癌患者来源异种移植瘤生物库，包含未经治疗的初始样本以及在新辅助化疗全程中的纵向样本。	Rinkenbaugh, A. L.	PDF	N/A	An annotated biobank of triple negative breast cancer patient-derived xenografts featuring treatment-naive and longitudinal samples throughout neoadjuvant chemotherapy
粘附-悬浮塑性促进循环肿瘤细胞的传播和定植	Huh, H. D.	PDF	N/A	Adherent-suspension plasticity promotes the dissemination and colonization of circulating tumor cells
含爱泼斯坦-巴尔病毒产物的外泌体促进鼻咽癌中与白血病抑制因子相关的巨噬细胞免疫抑制极化	Liu, T.-T.	PDF	N/A	Epstein-Barr viral product-containing exosome facilitates LIF-associated immunosuppressive polarization of macrophage in nasopharyngeal carcinoma
# BioRxiv 2024-11-27 Papers

标题	作者	PDF链接	代码仓库	Title
全基因组CRISPR筛选识别出由LRRK2调控的人类神经元摄取细胞外tau的途径	Evans, L. D.	PDF	N/A	Whole genome CRISPR screens identify a LRRK2-regulated pathway for extracellular tau uptake by human neurons
一个长达二十年的淡水湖泊微生物时间序列，介绍了limony和TYMEFLIES数据集。	Rohwer, R. R.	PDF	N/A	A two-decade microbial time series from a freshwater lake, introducing the limony and TYMEFLIES datasets
一种新的先验实用可辨识性方法	Thompson, P. A.	PDF	N/A	A new method for a priori practical identifiability
在清醒状态下通过致幻剂5-MeO-DMT诱导小鼠进入类似睡眠的状态	Breant, B. J.	PDF	N/A	Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice
非转基因动物中非侵入性光学合成听觉感觉	Tamai, Y.	PDF	N/A	Non-invasive optical synthetization of hearing sensation in non-genetically modified animal
内胚层细胞通过运动接触抑制来实现斑马鱼原肠胚形成期间均匀的细胞分散。	LaBelle, J.	PDF	N/A	Endodermal cells use contact inhibition of locomotion to achieve uniform cell dispersal during zebrafish gastrulation
亲吻素纤维及其受体分布分析表明其在中枢感觉处理和行为状态控制中的潜在作用	Zhang, L.	PDF	N/A	Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
ATP爆发是耻垢分枝杆菌抗生素致死性的主要驱动力。	Lodhiya, T.	PDF	N/A	ATP burst is the dominant driver of antibiotic lethality in Mycobacterium smegmatis
系统性4-1BB刺激在疟原虫感染期间增强了滤泡外记忆B细胞的形成和回忆反应。	Caloba, C.	PDF	N/A	Systemic 4-1BB stimulation augments extrafollicular memory B cell formation and recall responses during Plasmodium infection.
bamSliceR：一个用于快速跨队列变异分析的Bioconductor包	Huang, Y. P.	PDF	N/A	bamSliceR: a Bioconductor package for rapid, cross-cohort variant analysis
GFETM：基于基因组基础的嵌入式主题模型用于单细胞ATAC-seq建模	Fan, Y.	PDF	N/A	GFETM: Genome Foundation-based Embedded Topic Model for scATAC-seq Modeling
单分子直接RNA测序揭示了跨多个物种的表观转录组塑造	Xie, Y.-Y.	PDF	N/A	Single-Molecule Direct RNA Sequencing Reveals the Shaping of Epitranscriptome Across Multiple Species
利用适应度景观建模和强化学习加速蛋白质工程	Sun, H.	PDF	N/A	Accelerating protein engineering with fitness landscape modeling and reinforcement learning
细胞壁重塑和囊泡产生的维持在结核分枝杆菌中是相互关联的。	Salgueiro, V.	PDF	N/A	Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
干扰抑制仅在视网膜坐标中运作。	Ilksoy, Y. A.	PDF	N/A	Distractor suppression operates exclusively in retinotopic coordinates
Voronota-LT：高效、灵活且考虑溶剂的基于镶嵌分析的原子相互作用	Olechnovic, K.	PDF	N/A	Voronota-LT: efficient, flexible and solvent-aware tessellation-based analysis of atomic interactions
利用农畜的表观基因组数据注释和评估调控区域中的功能性变异	Ma, R.	PDF	N/A	Annotation and assessment of functional variants in regulatory regions using epigenomic data in farm animals
弯曲DNA会增加其螺旋重复	Chandrasekhar, S.	PDF	N/A	Bending DNA increases its helical repeat
Hist2Cell：从组织学图像中解析细粒度的细胞结构	ZHAO, W.	PDF	N/A	Hist2Cell: Deciphering Fine-grained Cellular Architectures from Histology Images
一种混合效应相似性矩阵回归模型（SMRmix），用于在群落水平上整合多个微生物组数据集	He, M.	PDF	N/A	A Mixed Effect Similarity Matrix Regression Model (SMRmix) for Integrating Multiple Microbiome Datasets at Community Level
使用蛋白质三维二级结构预测转录因子	Liebold, J.	PDF	N/A	Transcription factor prediction using protein 3Dsecondary structures
次优的再喂养补偿了幼年营养不良小鼠模型中的生长迟缓	Thoumas, J.-L.	PDF	N/A	Suboptimal refeeding compensates stunting in a mouse model of juvenile malnutrition
睫状蛋白IFT88的时间性消融改变了正常的脑波模式	Strobel, M. R.	PDF	N/A	Temporal Ablation of the Ciliary Protein IFT88 Alters Normal Brainwave Patterns
评估在快速并行视觉呈现后形态-正字法、词汇和语法处理的时间进程：一项针对英语的脑电图研究。	Dunagan, D.	PDF	N/A	Evaluating the timecourses of morpho-orthographic, lexical, and grammatical processing following rapid parallel visual presentation: an EEG investigation in English.
肠道菌群失调不可避免，但耐受性并非如此：小鼠微生物群在维持其丁酸盐生产能力的时间反应与对慢性吗啡的持续抗痛觉相关。	Sall, I. J.	PDF	N/A	Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic morphine
Tol-Pal复合体在细菌外膜脂质稳态中的主要作用	Tan, W. B.	PDF	N/A	Primary role of the Tol-Pal complex in bacterial outer membrane lipid homeostasis
在高风险乳腺癌中，通过甘草查尔酮A重新编程SREBP1依赖的脂质生成和炎症：癌症预防的新途径	Hajirahimkhan, A.	PDF	N/A	Reprogramming SREBP1-dependent lipogenesis and inflammation in high-risk breast with licochalcone A: a novel path to cancer prevention
可溶性免疫介质协调了结核分枝杆菌复合群各系之间保护性的体外肉芽肿反应。	Arbues, A.	PDF	N/A	Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages
解决分布不匹配问题以实现有效的半监督神经元分割	Zhang, Y.	PDF	N/A	Addressing Distribution Mismatch for Effective Semi-Supervised Neuron Segmentation
神经影像去噪器，用于去除功能成像中瞬时荧光信号的噪声。	Weissbach, S.	PDF	N/A	Neuroimage Denoiser for removing noise from transient fluorescent signals in functional imaging.
无损时空分辨率的多光谱活细胞成像	Kumar, A.	PDF	N/A	Multispectral live-cell imaging with uncompromised spatiotemporal resolution
自适应渐渗分类方法的性能评估	Romieu, J.	PDF	N/A	Performance evaluation of adaptive introgression classification methods
同化型NADPH依赖性亚硫酸盐还原酶的二聚化揭示了在最小界面上结合双黄素还原酶的元素	Ghazi Esfahani, B.	PDF	N/A	Dimerization of assimilatory NADPH-dependent sulfite reductase reveals elements for diflavin reductase binding at a minimal interface
二聚化同化NADPH依赖性亚硫酸盐还原酶的结构揭示了双黄素还原酶结合的最小界面	Ghazi Esfahani, B.	PDF	N/A	Structure of dimerized assimilatory NADPH-dependent sulfite reductase reveals the minimal interface for diflavin reductase binding
发现猴痘病毒H3中的硫酸乙酰肝素结合域作为抗痘病毒药物靶点：结合AI与MD模拟	Zheng, B.	PDF	N/A	Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combining AI and MD Simulations
多样本非负空间分解	Wang, Y.	PDF	N/A	Multi-sample non-negative spatial factorization
早期繁殖选择导致果蝇种群加速衰老和广泛代谢重塑	Hubert, D. L.	PDF	N/A	Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster populations
DNA序列的二维表示显示，大多数转换是与复制滑移相关的错配核苷酸。	Erives, A. J.	PDF	N/A	2D representations of DNA sequence show that most transversions are misaligned nucleotides associated with replication slippage.
婴儿脑电微状态动力学与在自然情境下与照顾者玩耍时婴儿注意力的细微模式相关	Bagdasarov, A.	PDF	N/A	Infant EEG microstate dynamics relate to fine-grained patterns of infant attention during naturalistic play with caregivers
全面化学分型和七种kisspeptin能神经元群体在小鼠大脑中的性腺调节	Hernandez, V. S.	PDF	N/A	Comprehensive chemotyping, and the gonadal regulation, of seven kisspeptinergic neuronal populations in the mouse brain
在形成、迁移和融合过程中，对三维肿瘤球体结构变化的非破坏性原位监测	Ning, K.	PDF	N/A	Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process
厌氧消化菌群中的代谢分离与功能基因簇	Wang, Y.	PDF	N/A	Metabolic Segregation and Functional Gene Clusters in Anaerobic Digestion Consortia
土壤微生物群落的持久性遗留效应有助于植物适应干旱反应	Ginnan, N. A.	PDF	N/A	Persistent legacy effects on soil microbiota facilitate plant adaptive responses to drought
揭示Galectin-1与脂质膜结合的GM1特异性	Scollo, F.	PDF	N/A	Unraveling the GM1 specificity of Galectin-1 binding to lipid membranes
在语言产生和理解过程中，前颞叶皮层中与语音学相关的特定一致性脑信号。	Dmitrieva, X.	PDF	N/A	Congruent brain signatures specific to phonology in fronto-temporal cortex during language production and understanding.
Unipept在2024年：扩展的宏蛋白质组学分析，支持遗漏切割、半胰蛋白酶和非胰蛋白酶肽段	Vande Moortele, T.	PDF	N/A	Unipept in 2024: Expanding metaproteomics analysis with support for missed cleavages, semi-tryptic and non-tryptic peptides
在基于模拟的历史人口遗传数据推断中，更优的置信区间	Rousset, F.	PDF	N/A	Better confidence intervals in simulation-based inference of historical demography from population genetic data
近北极地区的蝙蝠（Myotis bats）广泛的长寿与DNA病毒驱动的适应性	Vazquez, J. M.	PDF	N/A	Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats
非协变存储效应：平衡和正向定向选择对突变等位基因的影响，这些等位基因放大了随机适应性和人口波动	Kim, Y.	PDF	N/A	Noncovarying storage effect: balancing and positive directional selection on mutant alleles that amplify random fitness and demographic fluctuations
稳定性与灵活性：在计算机中重塑古菌膜	Amaral, M.	PDF	N/A	Stability vs flexibility: reshaping archaeal membranes in silico
先天抗病毒系统是鲍曼不动杆菌中驱动前噬菌体分布的主要防御系统组成部分。	Moreno-Rodriguez, A.	PDF	N/A	Innate antiviral systems are major defensome components that drive prophage distribution in Acinetobacter baumannii
PSTP：通过迁移学习和注意力机制解码蛋白质相分离的潜在序列语法	Feng, M.	PDF	N/A	PSTP: Decoding Latent Sequence Grammar for Protein Phase Separation through Transfer Learning and Attention
一种定义细胞类型特异性CTCF结合和染色质组织的基因组范围代码	Do, C.	PDF	N/A	A genome wide code to define cell-type specific CTCF binding and chromatin organization
肿瘤缺氧细胞外囊泡为三阴性乳腺癌创造了一个保护性微环境	Pachane, B. C.	PDF	N/A	Tumoral hypoxic extracellular vesicles create a protective microenvironment for triple-negative breast cancer
全息显微镜揭示了在血管内皮化过程中，无需标记的内皮细胞定量动态变化。	Leineweber, W. D.	PDF	N/A	Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization
PLM-interact：扩展蛋白质语言模型以预测蛋白质-蛋白质相互作用	Liu, D.	PDF	N/A	PLM-interact: extending protein language models to predict protein-protein interactions
线粒体的不均等分配在神经发生过程中促进不对称命运	Bunel, B.	PDF	N/A	Unequal mitochondrial segregation promotes asymmetric fates during neurogenesis
晚更新世巴西东南部灰侏儒鹿摄食策略的千年尺度稳定性。	Hubbe, A.	PDF	N/A	Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil.
稀疏矩阵分解能够稳健地处理全基因组关联研究（GWAS）中样本共享的问题，从而揭示出可解释的遗传成分。	Omdahl, A. R.	PDF	N/A	Sparse matrix factorization robust to sample sharing across GWAS reveals interpretable genetic components
发育阶段和细胞环境决定Ezh2Y641F突变在造血中的致癌和分子结果	Zimmerman, S. M.	PDF	N/A	Developmental Stage and Cellular Context Determine Oncogenic and Molecular Outcomes of Ezh2Y641F Mutation in Hematopoiesis
AlphaFold 对全基因组的预测概览	Cazals, F.	PDF	N/A	AlphaFold predictions on whole genomes at a glance
通过原位多聚腺苷酸化和空间RNA测序实现微生物群-宿主相互作用的高分辨率空间映射	Ntekas, I.	PDF	N/A	High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing
大肠杆菌细胞宽度稳态和膨胀动力学的力学机制：MreB和隔膜抑制的影响	Kale, T.	PDF	N/A	Mechanics of E. coli cell width homeostasis and bulging dynamics from MreB and septum inhibition
通过化学物质灌注去除兔心脏中的DNA含量，同时保持胶原蛋白和糖胺聚糖不变。	Seitzhaparova, B.	PDF	N/A	Perfusion via chemicals removes the DNA content of rabbit hearts while keeping the collagen and glycosaminoglycan unaltered
结核分枝杆菌中一种新型放线菌特异性核糖体休眠因子	Majumdar, S.	PDF	N/A	A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis
汉密尔顿法则的一般版本	van Veelen, M.	PDF	N/A	The general version of Hamilton's rule
在人类细胞中表达重组人谷氨酰化TTLLs会导致不同的微管谷氨酰化模式，只有TTLL6会破坏微管动力学。	Al Kabbani, M. A.	PDF	N/A	Expression of recombinant human glutamylating TTLLs in human cells leads to differential tubulin glutamylation patterns, with only TTLL6 disrupting microtubule dynamics
量子自旋共振在工程化磁敏荧光蛋白中的应用，使得活细胞内的多模态传感成为可能	Abrahams, G. J.	PDF	N/A	Quantum Spin Resonance in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells
多个冗余的羧酸转运蛋白支持恶性疟原虫的线粒体代谢	Rajaram, K.	PDF	N/A	MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN PLASMODIUM FALCIPARUM
细菌RNA中假尿苷的定量图谱	Sharma, S.	PDF	N/A	Quantitative mapping of pseudouridines in bacteria RNA
PyRID：一个用Python编写的反应性粒子和相互作用粒子的布朗动力学模拟器	Becker, M.	PDF	N/A	PyRID: A Brownian dynamics simulator for reacting and interacting particles written in Python
NaviNIBS：一个全面且开源的软件工具箱，用于神经导航的无创脑刺激。	Cline, C. C.	PDF	N/A	NaviNIBS: a comprehensive and open-source software toolbox for neuronavigated noninvasive brain stimulation.
剥脱性青光眼中的线粒体和微管缺陷	Venkatesan, A.	PDF	N/A	Mitochondrial and Microtubule Defects in Exfoliation Glaucoma
血小板因子4（PF4）调节造血干细胞衰老	Zhang, S.	PDF	N/A	Platelet Factor 4 (PF4) Regulates Hematopoietic Stem Cell Aging
利用杆状病毒载体成功递送CRISPR-Cas9至昆虫脑部目标	Dogan, B. E. K.	PDF	N/A	Successful delivery of CRISPR-Cas9 with a baculovirus vector for insect brain targets
TimeFlies：一种用于果蝇头部衰老时钟的snRNA-seq技术揭示了性别偏向的衰老现象	Tennant, N.	PDF	N/A	TimeFlies: an snRNA-seq aging clock for the fruit fly head sheds light on sex-biased aging
经过工程改造的CRISPR-碱基编辑器：家族性自主神经功能异常的永久性治疗方法	Yun, S.	PDF	N/A	Engineered CRISPR-Base Editors as a Permanent Treatment for Familial Dysautonomia
跑步机速度在步态周期内变化引起的四肢协调变化	Hall, B. L.	PDF	N/A	Changes in interlimb coordination induced by within-stride changes in treadmill speed
天生相连：婴儿是否已经具备与成人相似的多尺度连接网络？	Bajracharya, P.	PDF	N/A	Born Connected: Do Infants Already Have Adult-Like Multi-Scale Connectivity Networks?
快速语义处理：一项关于叙事文本阅读的MEG研究	Neklyudova, A.	PDF	N/A	Rapid Semantic Processing: An MEG Study of Narrative Text Reading
感觉运动同步经颅磁刺激（seTMS）能够增强运动皮层的兴奋性。	Ross, J. M.	PDF	N/A	Sensory Entrained TMS (seTMS) enhances motor cortex excitability
瞳孔大小变化揭示了认知算术中的贝叶斯推理	Zenon, A.	PDF	N/A	Pupil size variations reveal Bayesian inference in cognitive arithmetic
Rac1抑制可预防转甲状腺素蛋白淀粉样变多发性神经病变中的轴突细胞骨架功能障碍	Magalhaes, J.	PDF	N/A	Rac1 inhibition prevents axonal cytoskeleton dysfunction in Transthyretin Amyloid Polyneuropathy
个体差异在音乐熟悉度和音乐特征对放松时大脑活动的影响中的作用	Scarratt, R. J.	PDF	N/A	Individual differences in the effects of musical familiarity and musical features on brain activity during relaxation
化学标记法：一种通过体内钙成像识别细胞类型的化学遗传学方法	Ko, B.	PDF	N/A	Chemotagging: a chemogenetic approach for identifying cell types with in vivo calcium imaging
不同他汀类药物对亚麻醉氯胺酮抗运动障碍活性的影响存在差异	Bartlett, M. J.	PDF	N/A	Differential effects of statins on the anti-dyskinetic activity of sub-anesthetic ketamine
通过长程连接在皮层区域之间建立动态共识	Javadzadeh, M.	PDF	N/A	Dynamic consensus-building between neocortical areas via long-range connections
利用功能性超声成像技术探索乌鸦听觉端脑中的神经动力学	Liao, D. A.	PDF	N/A	Exploring Neural Dynamics in the Auditory Telencephalon of Crows using Functional Ultrasound Imaging
白质高信号和小型塑料颗粒	Bearer, E. L.	PDF	N/A	White matter hyperintensities and microplastics
白质微观结构与青少年、中年和晚年的大脑、身体和遗传特征相关联。	Korbmacher, M.	PDF	N/A	White matter microstructure links with brain, bodily and genetic attributes in adolescence, mid- and late life
一个人类化的神经元模型系统揭示了锰在神经元内吞作用、钙离子通量和线粒体生物能量学中的关键作用	Budinger, D.	PDF	N/A	A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics
个体化神经生理特征的寿命演变	da Silva Castanheira, J.	PDF	N/A	The Lifespan Evolution of Individualized Neurophysiological Traits
胰岛素抵抗、认知功能与肥胖老年人的功能性脑网络拓扑结构	McIntyre, C. C.	PDF	N/A	Insulin resistance, cognition, and functional brain network topology in older adults with obesity
鉴定出一种源自SARS-CoV2 S1蛋白的肽段，该肽段具有类似超抗原的T细胞刺激特性。	Tu, T. H.	PDF	N/A	The identification of a SARs-CoV2 S1 protein derived peptide with super-antigen-like stimulatory properties on T-cells
不同微气候下土壤微生物群落的比较分析	Pall, T.	PDF	N/A	Comparative analysis of microbial communities of soils under contrasting microclimates
在妊娠早期乳腺腺泡增殖和分化的转录调控	Garcia-Lerena, J.	PDF	N/A	Transcriptional Regulation of Mammary Alveolar Proliferation and Differentiation during Early Pregnancy
小鼠十二指肠在全身致死剂量辐射后恢复期间的转录组	He, L.	PDF	N/A	Transcriptome of the murine duodenum during recovery after a lethal dose of total body irradiation
一个特定谱系驱动因子库将果蝇腹神经索中发育中的神经回路与行为联系起来。	Soffers, J. H.	PDF	N/A	A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord.
通过光调控激酶对内源标记蛋白进行体内调控	vigano, a. m.	PDF	N/A	In vivo regulation of an endogenously-tagged protein by a light-regulated kinase
一种在头部固定小鼠中探索虚拟现实的环境性恐惧条件化范式。	Krishnan, S.	PDF	N/A	A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality.
分枝杆菌蛋氨酸氨肽酶1c型在30S核糖体亚基上兼职作为抗关联因子	Banerjee, A.	PDF	N/A	Mycobacterial methionine aminopeptidase type 1c moonlights as an anti-association factor on the 30S ribosomal subunit
通过冷冻电镜结合构建和检索方法，阐明天然血小板膜中整合素αIIb3的动力学	Han, X.	PDF	N/A	Elucidating the dynamics of Integrin αIIb3 from native platelet membranes by cryo-EM with build and retrieve method
重新布线大肠杆菌以将甲酸盐转化为甲基基团	Mohr, M. K. F.	PDF	N/A	Rewiring Escherichia coli to Transform Formate into Methyl Groups
成功建立了基于病毒复制元件的莱茵衣藻叶绿体外源基因表达系统	Jiang, Y.	PDF	N/A	Successful establishment of an exogenous gene expression system in Chlamydomnas chloroplast based on viral replication elements
优化的大肠杆菌亮氨酰-tRNA合成酶定向进化能够将许多非标准氨基酸加入真核生物遗传密码中，包括鸟氨酸和Nε-乙酰甲基赖氨酸。	Ficaretta, E. D.	PDF	N/A	Optimized directed evolution of E. coli leucyl-tRNA synthetase adds many noncanonical amino acids into the eukaryotic genetic code including ornithine and Nepsilon-acetyl-methyllysine
在缺氧-缺血性脑病体外模型中，物理调控的间充质干细胞分泌组具有更高的能力来保护神经网络和翻译过程。	Caramelo, I.	PDF	N/A	Physioxia-modulated mesenchymal stem cells secretome has higher capacity to preserve neuronal network and translation processes in hypoxic-ischemic encephalopathy in vitro model
UniSPAC：一种用于连接组学中校对和注释的统一分割框架	Deng, J.	PDF	N/A	UniSPAC: A Unified Segmentation Framework for Proofreading and Annotation in Connectomics
系统性暴露于新冠病毒样颗粒会调节活体小鼠大脑皮层神经元的放电模式。	Das, A.	PDF	N/A	Systemic exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the living mouse brain
视觉-前庭整合与自我运动：人类皮层区域V6偏好向前和对齐的刺激	Marchand, S.	PDF	N/A	Visuo-Vestibular Integration for Self-Motion: Human Cortical Area V6 Prefers Forward and Congruent Stimuli
青春期激素与青春期早期女性大脑：一项多模态脑部MRI研究	Khetan, M.	PDF	N/A	Pubertal hormones and the early adolescent female brain: a multimodality brain MRI study
纤毛病与新生儿麻醉相互作用，导致非凋亡性胱天冬酶介导的运动功能障碍	Saric, N.	PDF	N/A	Ciliopathy interacts with neonatal anesthesia to cause non-apoptotic caspase-mediated motor deficits
一种可编程的、无需选择的金黄色葡萄球菌CRISPR干扰系统	Miah, R.	PDF	N/A	A programmable, selection-free CRISPR interference system in Staphylococcus aureus
鉴定并基因表征了一种新型双节冠状病毒在小熊猫中的存在	chen, x.	PDF	N/A	Identification and genomic characterization of a novel bisegmented coronavirus in the lesser panda
对一个由宏基因组组装而成的基因组进行比较基因组分析，揭示了Mucoromycotina细根内生菌丛枝菌根真菌中独特的共生特征。	Cole, J.	PDF	N/A	Comparative genomic analysis of a metagenome-assembled genome reveals distinctive symbiotic traits in a Mucoromycotina fine root endophyte arbuscular mycorrhizal fungus
未被探索的种子微生物群中的酵母多样性	Marchi, M.	PDF	N/A	Unexplored Yeast diversity in Seed Microbiota
碳青霉烯类耐药高毒力肺炎克雷伯菌的分子流行病学：中国地区头孢他啶/阿维巴坦耐药的风险因素及耐药机制	Wang, N.	PDF	N/A	Molecular epidemiology of carbapenem-resistant hypervirulent Klebsiella pneumoniae: Risk factors and resistance mechanism of ceftazidime/avibactam in China
幽门螺杆菌孤儿ATTAAT特异性甲基转移酶M.Hpy99XIX在铁代谢相关基因的协调调控中起着核心作用。	Gottschall, W.	PDF	N/A	The Helicobacter pylori orphan ATTAAT-specific methyltransferase M.Hpy99XIX plays a central role in the coordinated regulation of genes involved in iron metabolism
弓形虫的代谢适应性与营养摄取：从摄入途径缺陷型突变体中获得的启示	Rimple, P. A.	PDF	N/A	Metabolic Adaptability and Nutrient Scavenging in Toxoplasma gondii: Insights from Ingestion Pathway-Deficient Mutants
采用新型多重qPCR技术，在唾液中鉴定出大量aliC和aliD基因，以提高特异性，对II组非荚膜肺炎球菌进行表征。	Laxton, C. S.	PDF	N/A	An abundance of aliC and aliD genes were identified in saliva using a novel multiplex qPCR to characterize group II non-encapsulated pneumococci with improved specificity
基于人群的元蛋白质组学揭示了肠道微生物群与表型之间的功能关联	Liang, S.	PDF	N/A	Population-based metaproteomics reveals functional associations between gut microbiota and phenotypes
广泛存在的一类孔形成效应器扩大了沙雷氏菌VI型分泌系统的影响	Reglinski, M.	PDF	N/A	A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system
2022年来自谱系2.3.4.4b的禽流感H5N1病毒比2005年来自谱系2.3.2.1的H5N1病毒在人类呼吸道上皮细胞中更好地附着和复制。	Bauer, L.	PDF	N/A	A 2022 avian H5N1 influenza A virus from clade 2.3.4.4b attaches to and replicates better in human respiratory epithelium than a 2005 H5N1 virus from clade 2.3.2.1
炎性间质基质细胞和IFN反应性T细胞是CHIP和MDS中人类骨髓微环境重塑的关键介质。	Prummel, K. D.	PDF	N/A	Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDS
通过瞬时递送CRISPR表观基因组编辑器核糖核蛋白实现可编程的表观基因组编辑	Nunez, J. K.	PDF	N/A	Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins
使用多重Cas12a sgRNA实现体内基因敲除并消除脱靶效应	Port, F.	PDF	N/A	Enhanced in vivo gene knockout with undetectable off-targets using multiplexed Cas12a sgRNAs
配对CRISPR筛选以绘制顺式和反式基因调控	Xue, X.	PDF	N/A	Paired CRISPR screens to map gene regulation in cis and trans
氨基酸酰-RNA环闭合连接的立体选择性	Kim, S.	PDF	N/A	Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation
通过促炎性S100A9和与神经退行性疾病相关的α-突触核蛋白形成异型液滴	Veiveris, D.	PDF	N/A	Heterotypic droplet formation by pro-inflammatory S100A9 and neurodegenerative disease-related alpha-synuclein
广泛存在的肠杆菌过氧化物酶包封体的结构和生化特性	Ubilla-Rodriguez, N. C.	PDF	N/A	Structural and biochemical characterization of a widespread enterobacterial peroxidase encapsulin
肽类凝聚体递送以在细胞内形成稳定的相互作用枢纽	Tu, W.	PDF	N/A	Delivery of Peptide Coacervates to Form Stable Interaction Hubs In Cells
使用3T fMRI区分脑干中相邻体感核团的活动	Howell, P.	PDF	N/A	Distinguishing the activity of adjacent somatosensory nuclei within the brainstem using 3T fMRI
紊乱的海马再激活可预测阿尔茨海默病小鼠模型中的空间记忆缺陷	Shipley, S.	PDF	N/A	Disordered Hippocampal Reactivations Predict Spatial Memory Deficits in a Mouse Model of Alzheimer's Disease
一种用于抗生素优化的生成式人工智能方法	Torres, M. D. T.	PDF	N/A	A generative artificial intelligence approach for antibiotic optimization
PACT与ADAR1在防止自源双链RNA异常激活PKR中的协同作用	Manjunath, L.	PDF	N/A	Cooperative Role of PACT and ADAR1 in Preventing Aberrant PKR Activation by Self-Derived Double-Stranded RNA
色氨酸饥饿对包涵体膜组成及衣原体-宿主相互作用的影响	Riffaud-Widner, C. M.	PDF	N/A	Effect of tryptophan starvation on inclusion membrane composition and chlamydial-host interactions
# BioRxiv 2024-11-26 Papers

标题	作者	PDF链接	代码仓库	Title
量化种内性状变异和种间性状相关性对相互作用种群的影响——一种非线性平均方法	van Benthem, K. J.	PDF	N/A	Quantifying the effects of intraspecific trait variation and interspecific trait correlations on interacting populations - a nonlinear averaging approach
通过基因拷贝数变异揭示的尼安德特人、丹尼索瓦人和智人的遗传饮食适应性	Vicedomini, R.	PDF	N/A	Genetic dietary adaptation in Neandertal, Denisovan and Sapiens revealed by gene copy number variation
一个基于网络的水生指示物种大型溞组织学图谱	Ngu, M. S.	PDF	N/A	A web-based histology atlas for the freshwater sentinel species Daphnia magna
腹侧视觉通路中的有机卷积可以解释V4区形状调谐的多样性	Gold, C. S.	PDF	N/A	Organic Convolution in The Ventral Visual Pathway Can Explain the Variety of Shape Tuning in Area V4
泛素化蛋白质组分析鉴定卡波西肉瘤疱疹病毒裂解再激活中的新宿主因子	Causey, A.	PDF	N/A	Analysis of the ubiquitin-modified proteome identifies novel host factors in Kaposi's sarcoma herpesvirus lytic reactivation
动作电位的消亡导致神经元之间的电耦合	Schloetter, M.	PDF	N/A	Annihilation of action potentials induces electrical coupling between neurons
海马体中相关事件的区分有助于记忆在发育过程中的再激活	Varga, N. L.	PDF	N/A	Differentiation of related events in hippocampus supports memory reinstatement in development
SARS-CoV-2感染人多能干细胞衍生的血管细胞揭示了平滑肌细胞在感染期间作为血管病理学的关键介质。	Richards, A.	PDF	N/A	SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection
小鼠8细胞胚胎中启动了一波新的DNA甲基化，与H3K27me3共同调控印记X染色体失活。	Yue, Y.	PDF	N/A	A wave of minor de novo DNA methylation initiates in mouse 8-cell embryos and co-regulates imprinted X- chromosome inactivation with H3K27me3
寄生虫复杂生命周期中的多重感染	Nguyen, P. L.	PDF	N/A	On multiple infections by parasites with complex life cycles
胶质母细胞瘤和其他颅内肿瘤会引发全身性的交感神经活动过度，从而限制了免疫治疗的效果。	Lorrey, S. J.	PDF	N/A	Glioblastoma and other intracranial tumors elicit systemic sympathetic hyperactivity that limits immunotherapeutic responses
Meteorins调节左右组织者的形成以及脊椎动物身体不对称性的建立。	Eggeler, F.	PDF	N/A	Meteorins regulate the formation of the left-right organizer and the establishment of vertebrate body asymmetry
压应力通过侧向张力和Piezo1驱动形态发生性凋亡	Merle, T.	PDF	N/A	Compressive stress drives morphogenetic apoptosis through lateral tension and Piezo1
RNAformer：一种简单而有效的同源性感知RNA二级结构预测模型	Franke, J. K. H.	PDF	N/A	RNAformer: A Simple yet Effective Model for Homology-Aware RNA Secondary Structure Prediction
在隐球菌中，Shugoshin对Bub1激酶活性的依赖对于维持纺锤体组装检查点反应并非必需。	Polisetty, S. D.	PDF	N/A	The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans
单倍体型解析的癌症核型重建与功能解析	Brunette, G. J.	PDF	N/A	Haplotype-resolved reconstruction and functional interrogation of cancer karyotypes
HSV-1感染导致+1核小体的下游移位	Weiss, E.	PDF	N/A	HSV-1 infection induces a downstream-shift of the +1 nucleosome
利用直接RNA测序技术探究酶依赖的假尿苷酸化，以评估神经元表转录组的可塑性	Fanari, O.	PDF	N/A	Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess neuronal epitranscriptome plasticity
机械力通过mTORC2-PKC途径调控心内膜Notch活化	Mu, Y.	PDF	N/A	Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway
睫状蛋白IFT88的时间性消融改变了正常的脑电波模式	Strobel, M. R.	PDF	N/A	Temporal Ablation of the Ciliary Protein IFT88 Alters Normal Brainwave Patterns
在活体中对鸟类上皮应用组织尺度的张力，以研究多尺度力学和胚层间耦合	Oikonomou, P.	PDF	N/A	Application of tissue-scale tension to avian epithelia in vivo to study multiscale mechanics and inter-germ layer coupling
非超突变癌症通过逆转种系突变偏倚来获得驱动突变。	Tuffaha, M. Z.	PDF	N/A	Non-hypermutator cancers access driver mutations through reversals in germline mutational bias
使用纳米孔直接RNA测序（DRS）进行mRNA psi图谱分析揭示了细胞类型特异性的假尿苷酸化	McCormick, C. A.	PDF	N/A	mRNA psi profiling using nanopore DRS reveals cell type-specific pseudouridylation
叶绿体单线态氧信号通过植物U-Box 4介导，导致RNA全局变化，叶绿体铁螯合酶二突变体的转录组分析揭示了这一过程。	Rai, S.	PDF	N/A	Transcript profiling of plastid ferrochelatase two mutants reveals that chloroplast singlet oxygen signals lead to global changes in RNA profiles and are mediated by Plant U-Box 4
快速进化转变和重叠的性偏倚基因表达模式变异使得性别的简单二元分类变得困难。	Xie, C.	PDF	N/A	Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary classification of sexes
PEX14在人类细胞中作为连接optineurin和peroxisome自噬的分子桥梁。	Li, H.	PDF	N/A	PEX14 functions as a molecular link between optineurin and pexophagy in human cells
静水流深：形态保守的多板纲动物进化中的大规模基因组重排	Sigwart, J. D.	PDF	N/A	Still waters run deep: Large scale genome rearrangements in the evolution of morphologically conservative Polyplacophora
因果、预测还是观察？不良结局路径中关键事件关系的不同理解及其对实践的影响	Zhou, Z.	PDF	N/A	Causal, Predictive or Observational? Different Understandings of Key Event Relationships for Adverse Outcome Pathways and Their Implications on Practice
重建自始新世以来欧亚淡水鱼类（鳅科）的系统发育和进化历史	Slechtova, V.	PDF	N/A	Reconstructing the phylogeny and evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene
人类微生物组来源的肽通过分子模拟影响实验性自身免疫性脑脊髓炎的发展	Ma, X.	PDF	N/A	Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicry
持久、私有和移动基因：进化泛基因组中基因动态模型	Gamblin, J.	PDF	N/A	Persistent, Private and Mobile genes: a model for gene dynamics in evolving pangenomes
重塑信息格局：将Waddington景观应用于衰老信息论与表观遗传再生	Wu, Y.	PDF	N/A	Transform the Information Landscape: Applying Waddington Landscape to Information Theory of Aging and Epigenetic Rejeuvanation
整合分子动力学模拟解析交联数据，揭示线粒体蛋白质分布	Schuhmann, F.	PDF	N/A	Integrative Molecular Dynamics Simulations Untangle Cross-Linking Data to Unveil Mitochondrial Protein Distributions
鸟类词汇地图集：一个全球英语鸟类名称描述性类别数据库	Morrison, E. S.	PDF	N/A	AvianLexiconAtlas: A database of descriptive categories of English-language bird names around the world
对单极刷状细胞施加逼真的苔藓纤维输入模式，会引发一系列时间响应，这些响应由不同谷氨酸受体介导的成分组成。	Huson, V.	PDF	N/A	Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors
在人类肺癌恶病质的新型临床前模型中，早期脂肪组织消耗	Snoke, D. B.	PDF	N/A	Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexia
环氧化酶-2的破坏易导致保留射血分数的心力衰竭	Ricciotti, E.	PDF	N/A	Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction
确定内在无序蛋白质在原子分辨率下的精确构象集合	Borthakur, K.	PDF	N/A	Determining accurate conformational ensembles ofintrinsically disordered proteins at atomic resolution
p62纤维的结构组织及富含钙的p62包裹脂滴货物的细胞超微结构	Berkamp, S.	PDF	N/A	Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo
阿拉斯加红藻Devaleraea mollis和Palmaria hecatensis的培养方案	Dittrich, M.	PDF	N/A	Cultivation protocols the rhodophytes, Devaleraea mollis and Palmaria hecatensis from Alaska
开发自主神经系统多尺度神经连接知识库	Imam, F. T.	PDF	N/A	Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System
揭示椋鸟群集体逃逸的机制	Papadopoulou, M.	PDF	N/A	Revealing mechanisms underlying the collective escape of starling flocks
细菌核糖体药物结合残基的自然变异	Ekemezie, C. L.	PDF	N/A	Natural variation in the drug-binding residues of bacterial ribosomes
基因尺度体外重建揭示组蛋白乙酰化直接调控染色质结构	Fukai, Y.	PDF	N/A	Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture
血管转录因子TMO5调控PIN1极性和器官发生，位于茎尖分生组织中MONOPTEROS的下游	Kareem, A.	PDF	N/A	Vascular Transcription Factor TMO5 Regulates PIN1 Polarity andOrganogenesis Downstream of MONOPTEROS in the Shoot Meristem
晚更新世巴西东南部灰侏儒鹿摄食策略的千年尺度稳定性。	Hubbe, A.	PDF	N/A	Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil.
注意你的光谱：验证同位素组蛋白肽段形式鉴定时需要注意的要点	Hijazi, H.	PDF	N/A	Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms
鉴定和表征类衣原体细菌Simkania negevensis的泛素E3 RING连接酶	Hörner, E.-M.	PDF	N/A	Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis
协调蛋白模块在人卵巢癌模型中单细胞分辨率下定义卡铂诱导的DNA损伤反应	Bedia, J. S.	PDF	N/A	Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models
两种入侵性蚧虫（铁杉毛蚧和菠萝瘿蚧）的基因组使得对烟碱型乙酰胆碱受体的特征描述成为可能。	Glendening, A. M.	PDF	N/A	Genomes of two invasive Adelges species (hemlock woolly adelgid and pineapple gall adelgid) enable characterization of nicotinic acetylcholine receptors
同时抑制COX-1和COX-2不足以引发与长期使用非甾体抗炎药相关的肠病。	Barekat, K.	PDF	N/A	Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use
结核分枝杆菌中一种新型放线菌特异性核糖体休眠因子	Majumdar, S.	PDF	N/A	A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis
线粒体自噬有助于维持细胞质蛋白质稳态，以保护心脏功能	Diwan, A.	PDF	N/A	Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function
脂肪源性间充质干细胞与视网膜色素上皮细胞在应激环境中的相互作用通过隧道纳米管进行	Gozel, M.	PDF	N/A	Adipose-derived Mesenchymal Stem Cells and Retinal Pigment Epithelial Cells Interactions in Stress Environment via Tunneling Nanotubes
自噬抑制在低氧条件下诱导急性髓系白血病细胞死亡并增强化疗效果	Wang, E. S.	PDF	N/A	Autophagy inhibition induces AML cell death and enhances the efficacy of chemotherapy under hypoxia
S100A4和TIGIT的联合抑制通过激活T细胞和NK细胞抑制晚期乳腺癌向肺部的转移	Leu, J.-S.	PDF	N/A	Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells
Th1细胞是富含髓系细胞的血管周围激活生态位的关键组织者。	Bala, N.	PDF	N/A	Th1 cells are critical tissue organizers of myeloid-rich perivascular activation niches.
DOA/CLK2磷酸化Fl(2)d/WTAP以增强m6A mRNA甲基转移酶复合物的活性	McQuarrie, D. W.	PDF	N/A	DOA/CLK2 phosphorylates Fl(2)d/WTAP to enhance m6A mRNA methyltransferase complex activity
跨父系环境和遗传背景的代际遗传的胚胎特征	Dura, M.	PDF	N/A	Embryonic Signatures of Intergenerational Inheritance across Paternal Environments and Genetic Backgrounds
TonB依赖受体和氧化酶在铜抗性中的作用，该抗性与铁依赖性相关，在弯曲芽孢杆菌中	Cherry, P.	PDF	N/A	Role of a TonB-dependent receptor and an oxygenase in iron-dependent copper resistance in Caulobacter crescentus
通过片段重复实现的可进化性遵循物种特异性动力学	Islam, S.	PDF	N/A	Evolvability through segmental duplication follows species-specific dynamics
通过转录激活在哺乳动物生殖细胞中启动基因启动子处的表观遗传景观	Li, P.	PDF	N/A	Priming Epigenetic Landscape at Gene Promoters through Transcriptional Activation in Mammalian Germ Cells
逐步破坏大肠杆菌RNA聚合酶-{lambda}R启动子接触和转录起始中的气泡塌陷的证据	Rector, M. J.	PDF	N/A	Evidence for Stepwise Disruption of E. coli RNA Polymerase-{lambda}R Promoter Contacts and Bubble Collapse in Transcription Initiation
使用RAG的大型语言模型在自动标注表型描述方面的有效性	Kainer, D.	PDF	N/A	The effectiveness of Large Language Models with RAG for auto-annotating phenotype descriptions
临床实践中的生物信息学建议	Lavrichenko, K.	PDF	N/A	Recommendations for Bioinformatics in Clinical Practice
CHARMER：检测和协调跨组织和Hi-C协议的高置信度染色质相互作用	Cole, S.	PDF	N/A	CHARMER: detecting and harmonizing high-confidence chromatin interactions across tissues and Hi-C protocols
Sirt5通过抑制ANT2的乳酸化来保护心脏功能免受缺血-再灌注损伤。	Zhang, L.	PDF	N/A	Sirt5 preserves cardiac function in ischemia-reperfusion injury by inhibiting ANT2 lactylation
腿部固定及随后的恢复期抗阻训练对年轻健康成年人骨骼肌血管生成相关标志物的影响，与先前的抗阻训练经验无关。	McIntosh, M. C.	PDF	N/A	Leg immobilization and subsequent recovery resistance training affect skeletal muscle angiogenesis related markers in young healthy adults regardless of prior resistance training experience
弥合巴西生物科学家Python培训差距：改进与挑战	Crestana, G. S.	PDF	N/A	Bridging the Python Training Gap for Bioscientists in Brazil: Improvements and Challenges
单脉冲电刺激人脑的细胞类型特异性反应	Cowan, R. L.	PDF	N/A	Cell-type specific responses to single-pulse electrical stimulation of the human brain
离线5Hz-rTUS诱发皮层脊髓兴奋性双盲重复实验失败	Fong, P.-Y.	PDF	N/A	Failed Double-Blind Replication of Offline 5Hz-rTUS-Induced Corticospinal Excitability
通过静息脑熵（BEN）揭示了鼻内催产素给药的年龄依赖性效应。	Song, D.	PDF	N/A	Age-dependent effects of intranasal oxytocin administration were revealed by resting brain entropy (BEN)
铜绿假单胞菌介导的心脏功能障碍是由感染期间释放的胞外囊泡驱动的。	Rajaram, M. V. S.	PDF	N/A	Pseudomonas aeruginosa-mediated cardiac dysfunction is driven by extracellular vesicles released during infection
聚磷酸盐积累的贝氏硫细菌垫的非凡生理特征表明，磷酸盐缓冲在海洋沉积物中起着关键作用。	Iakovchuk, N.	PDF	N/A	Extraordinary physiology of polyphosphate-accumulating Beggiatoa mats suggests a key role for phosphate buffering in marine sediments
组蛋白伴侣Spt6通过其保守的N端结构域控制染色质结构	Warner, J. L.	PDF	N/A	The histone chaperone Spt6 controls chromatin structure through its conserved N-terminal domain
一个用于绘制生物多样性、气候和可持续发展关键生命支持区（ELSAs）的操作框架	Venter, O.	PDF	N/A	An operational framework to map Essential Life Support Areas (ELSAs) for biodiversity, climate, and sustainable development
使用总蛋白方法对保留和降低射血分数的心力衰竭患者进行AI驱动的分类	Lenzi, A.	PDF	N/A	AI-driven Classification of Heart Failure Preserved and Reduced Ejection Fraction Patients Using the Total Protein Approach
Bwa，一种碱性神经酰胺酶-ACER2的直系同源物，通过促炎细胞因子信号传导促进果蝇肠道干细胞增殖。	Rahman, M. M.	PDF	N/A	Bwa, an ortholog of alkaline ceramidase-ACER2, promotes intestinal stem cell proliferation through pro-inflammatory cytokine signaling in Drosophila melanogaster
肾足细胞的线粒体呼吸能力较高，且随年龄变化，并具有性别二态性。	Campbell, M. D.	PDF	N/A	Mitochondrial respiratory capacity in kidney podocytes is high, age-dependent, and sexually dimorphic.
探讨癌症患者对微生物组工程技术态度的研究	Owen, K. A.	PDF	N/A	Engaging cancer patients on their attitudes towards microbiome engineering technologies
侧化的记忆网络解释了昆虫导航中使用的高阶视觉特征	Filippi, G.	PDF	N/A	Lateralised memory networks explain the use of higher-order visual features in navigating insects
增强的Notch依赖性胶质生成和延迟的生理成熟是Lowe综合征中神经发育缺陷的基础	Sharma, Y.	PDF	N/A	Enhanced Notch dependent gliogenesis and delayed physiological maturation underlie neurodevelopmental defects in Lowe syndrome
细胞和髓鞘构筑图谱指导下的灰质和白质结构特性的耦合老化	Hoagey, D. A.	PDF	N/A	Coupled aging of cyto- and myeloarchitectonic atlas-informed gray and white matter structural properties
跨参考框架的多感官整合与加法前馈网络	Farahmandi, A.	PDF	N/A	Multisensory integration across reference frames with additive feed-forward networks
在狼疮性肾炎中，纤维化区域的炎症先于肾功能的丧失。	Malvica, S.	PDF	N/A	Inflammation in Areas of Fibrosis Precedes Loss of Kidney Function in Lupus Nephritis
欧洲受保护地区面临气候变化的加速暴露	Cimatti, M.	PDF	N/A	The accelerating exposure of European protected areas to climate change
婴儿代谢的动态全身模型	Zaunseder, E.	PDF	N/A	Dynamic whole-body models for infant metabolism
有额颞叶痴呆家族史的无症状个体尿液蛋白质的变化	Su, Y.	PDF	N/A	Changes in urinary proteins of unaffected individuals with a family history of frontotemporal dementia
谱系特异性性状变异导致入侵性多宿主野生动物寄生虫中广泛存在同时共存和竞争排斥动态	Garner, T. W.	PDF	N/A	Lineage-specific trait variation generates widespread, contemporaneous coexistence and competitive exclusion dynamics in an invasive, multihost wildlife parasite
汉密尔顿法则的一般版本	van Veelen, M.	PDF	N/A	The general version of Hamilton's rule
使用边缘计算的玻璃体视网膜手术术中增强现实	Ye, R. Z.	PDF	N/A	Intraoperative Augmented Reality for Vitreoretinal Surgery using Edge Computing
通过ROCK抑制在蛋白酶可降解水凝胶中促进人唾液腺干细胞/祖细胞的极化和分化	Metkari, A.	PDF	N/A	Promoting Polarization and Differentiation of Primary Human Salivary Gland Stem/Progenitor Cells in Protease-Degradable Hydrogels via ROCK Inhibition
iSIM-sigma：分子相似性高效标准差计算	Perez, K. L.	PDF	N/A	iSIM-sigma: efficient standard deviation calculation for molecular similarity
SPACE：STRING蛋白质作为互补嵌入	Hu, D.	PDF	N/A	SPACE: STRING proteins as complementary embeddings
DockFormer：利用成对Transformer高效预测多模态受体-配体相互作用	Shor, B.	PDF	N/A	DockFormer: Efficient Multi-Modal Receptor-Ligand Interaction Prediction using Pair Transformer
利用独特性：在弹性奠基图上的种子-链-延伸对齐	Rizzo, N.	PDF	N/A	Exploiting uniqueness: seed-chain-extend alignment on elastic founder graphs
DyNDG：基于时间序列动态网络整合差异基因识别白血病相关基因	A, J.	PDF	N/A	DyNDG: Identifying Leukemia-Related Genes based on the Time-Series Dynamical Network by Integrating Differential Genes
LRRC8A:D体积调节阴离子通道的组装与脂质调控	Lurie, A.	PDF	N/A	Assembly and lipid-gating of LRRC8A:D volume-regulated anion channels
利用实验血管数据进行高分辨率脑肿瘤模拟	Behle, E.	PDF	N/A	Leveraging Experimental Vasculature Data for High Resolution Brain Tumor Simulations
黑色素瘤患者前哨淋巴结中的免疫组织对远处转移具有预后意义	Amitay, Y.	PDF	N/A	Immune organization in sentinel lymph nodes of melanoma patients is prognostic of distant metastases
重复给予药用级中链甘油三酯（一种常见的药理学辅料），通过腹腔注射而非口服途径在小鼠中表现出剂量依赖性毒性。	Adler-Wachter, M.	PDF	N/A	Repeated administration of pharmaceutical-grade medium chain triglycerides, a common pharmacologic excipient, confers dose-dependent toxicity by the intraperitoneal but not oral route in mice
识别新型药物相互作用：迈向女性生殖健康精准医学	Garcia-Acero, P.	PDF	N/A	Identification of novel drug-drug interactions: towards precision medicine in women's reproductive health
比较转录组学分析揭示了由Pantoea agglomerans pv. betae的III型效应子操控的候选基因，这些基因导致了甜菜根瘤的形成。	Gupta, P.	PDF	N/A	Comparative transcriptomic profile reveals candidate genes manipulated by type III effectors of Pantoea agglomerans pv. betae leading to gall formation in beet
蒸腾作用洞察：通过高级建模估算蒸腾作用	Friedman, S.	PDF	N/A	Transpiration Insights: Estimating Transpiration Through Advanced Modeling
评估法国本土人口暴露于农药施用的程度，采用高分辨率的农药使用强度地图	Nowak, B.	PDF	N/A	Assessment of population exposure to pesticide applications with a high-resolution map of pesticide use intensity for mainland France
cpTatC蛋白的N端结构域与叶绿体TAT转运中的前体成熟结构域相互作用	Maddethalawe, T.	PDF	N/A	The N-terminal Domain of cpTatC Protein Interacts with the Precursor Mature Domain in Chloroplast TAT Translocation
海洋硅藻三角褐指藻（Phaeodactylum tricornutum）对生长素（auxin）的生理、转录组和代谢组响应	Chen, Y.-T.	PDF	N/A	Physiological, transcriptomic and metabolomic responses of the marine diatom Phaeodactylum tricornutum to auxin
完整的菠菜叶绿体中类囊体膜的分子结构	Wietrzynski, W.	PDF	N/A	Molecular architecture of thylakoid membranes within intact spinach chloroplasts
OsbHLH089和OsbHLH094通过调节OsSLR1水平来维持水稻的雄性生殖适应性	Fernandes, T.	PDF	N/A	OsbHLH089 and OsbHLH094 Modulate OsSLR1 Levels to Maintain Male Reproductive Fitness in Rice
使用Microsoft Sway作为药剂学实验课程中生成数据的存储库：一项关于外用制剂特性表征的案例研究	Chen, Q.	PDF	N/A	Employing Microsoft Sway as a Repository for Data Generated in Pharmaceutics Experimental Courses: A Case study on Topical Formulation Characterization
预处理脂肪间充质干细胞衍生的外泌体对贝赫切特葡萄膜炎免疫调节的影响	Gozel, M.	PDF	N/A	Effects of Primed Adipose Mesenchymal Stem Cell-Derived Exosomes on Immunomodulation in Behcet Uveitis
在人类细胞中表达重组人谷氨酰化TTLLs会导致不同的微管谷氨酰化模式，其中只有TTLL6会破坏微管动力学。	Al Kabbani, M. A.	PDF	N/A	Expression of recombinant human glutamylating TTLLs in human cells leads to differential tubulin glutamylation patterns, with only TTLL6 disrupting microtubule dynamics
使用新型造影剂对髓核进行高分辨率三维显微CT成像	Buckles, M. M.	PDF	N/A	High-resolution 3-dimensional micro-CT imaging of the nucleus pulposus using a novel contrast agent
亚热带树木生物多样性实验中，物种内和个体内的性状变异性随树种丰富度的增加而降低。	Castro Sanchez-Bermejo, P.	PDF	N/A	Intraspecific and intraindividual trait variability decrease with tree species richness in a subtropical tree biodiversity experiment
沿海盐沼滨螺Littoraria irrorata的生态关联：现场和实验室证据表明其对植被栖息地的偏好	Klinges, D. H.	PDF	N/A	Ecological associations of the coastal marsh periwinkle snail Littoraria irrorata: field and laboratory evidence of vegetation habitat preferences
多物种生态动力学中结构化与随机相互作用的相互作用	Giral Martinez, J.	PDF	N/A	Interplay of structured and random interactions in many-species ecological dynamics
海拔和海洋屏障塑造了新西兰卡波卡波瓦伊（Uropetala）蜻蜓的分布、扩散和多样性	Tolman, E. R.	PDF	N/A	Elevational and Oceanic Barriers Shape the Distribution, Dispersal and Diversity of Aotearoa's Kapokapowai (Uropetala) Dragonflies
解锁两栖植物适应的秘密：RNA修饰的作用	Mazdziarz, M. A.	PDF	N/A	Unlocking the Secrets of Amphibious Plant Adaptation: The Role of RNA Modifications
真菌GPCR基因家族的鉴定与分类	LIU, Z.	PDF	N/A	Identification and Classification of Fungal GPCR Gene Families
基因组语言模型的局限性与增强：动态选择方法	Qiu, S.	PDF	N/A	Limitations and Enhancements in Genomic Language Models: Dynamic Selection Approach
氯化物遗传编码指示剂的定向进化	Peng, W.	PDF	N/A	Directed Evolution of a Genetically Encoded Indicator for Chloride
脂肪组织的机械各向异性调节卵巢癌的侵袭	Gonzalez-Molina, J.	PDF	N/A	The mechanical anisotropy of adipose tissues regulates ovarian cancer invasion
基于强化学习的电机脑机接口软件模拟器	Liang, K.-F.	PDF	N/A	A reinforcement learning based software simulator for motor brain-computer interfaces
VaxLLM：利用微调的大型语言模型进行布鲁氏菌疫苗的自动化标注	Li, X.	PDF	N/A	VaxLLM: Leveraging Fine-tuned Large Language Model for automated annotation of Brucella Vaccines
利用人类泛蛋白组提升蛋白质组学和元蛋白质组学中的肽段和蛋白质鉴定能力	Canderan, J.	PDF	N/A	Leveraging the Human Panproteome to Enhance Peptide and Protein Identification in Proteomics and Metaproteomics
通过计算机模拟发现大肠杆菌中芳香族氨基酸生产的靶点	Fonseca, A. P.	PDF	N/A	In silico target discovery for aromatic amino acid production in Escherichia coli
OrthologAL：一个用于非人类临床前高维基因表达数据质量感知人源化的Shiny应用程序	CHOWDARY, R.	PDF	N/A	OrthologAL: A Shiny application for quality-aware humanization of non-human pre-clinical high-dimensional gene expression data
使用二甲双胍针对更年期过渡期可改善乳腺癌预后，但停药对代谢健康有不利影响：来自绝经后乳腺癌的临床前模型研究结果。	Corleto, K. A.	PDF	N/A	Targeting the menopause transition with metformin improves breast cancer outcomes, but discontinuation has deleterious effects on metabolic health: Findings from a preclinical model of postmenopausal breast cancer.
在癌症中，CD47相对于CD24在巨噬细胞免疫检查点中占主导地位。	Allen, J.	PDF	N/A	CD47 predominates over CD24 as a macrophage immune checkpoint in cancer.
逐步组装冠爬行动物解剖结构：晚古生代新双孔类旁系群阐明	Jenkins, X.	PDF	N/A	Stepwise Assembly Of Crown Reptile Anatomy Clarified By Late Paleozoic Outgroups Of Neodiapsida
内皮细胞中的RIPK3可减轻缺血-再灌注损伤中的器官特异性炎症和血管通透性	Johnson, C. F.	PDF	N/A	Endothelial RIPK3 minimizes organotypic inflammation and vascular permeability in ischemia-reperfusion injury
植物易感性的组织非依赖性：通过根和叶对系统性植物病原菌拉氏假单胞菌在茄子和番茄幼苗中的比较致病性研究	Bhuyan, S.	PDF	N/A	Tissue-independent nature of plant susceptibility: a comparative pathogenicity study of the systemic phytopathogen Ralstonia pseudosolanacearum in eggplant and tomato seedlings through root and leaf
一种基于质量源于设计（QbD）的策略，用于开发同时负载姜黄素和siRNA的脂质体复合物，以对抗与骨关节炎相关的炎症和氧化应激。	Ranamalla, S. R.	PDF	N/A	A QbD strategy to develop curcumin and siRNA co-loaded lipoplexes to combat osteoarthritis-related inflammation and oxidative stress
溶酶体钙信号通过钙刺激的腺苷酸环化酶1和8介导急性α-肾上腺素能反应	Akerman, E.	PDF	N/A	Lysosomal calcium signalling contributes to the acute α-adrenergic response via calcium-stimulated adenylyl cyclase 1 and 8
心房心肌细胞中的心房颗粒作为酸性钙储存库	Akerman, E.	PDF	N/A	Atrial Granules in Atrial Cardiomyocytes as Acidic Calcium Stores
鉴定调控启动子序列在蒺藜苜蓿（Medicago truncatula）根瘤衰老初期指导MtCP6转录的作用。	Yang, L.	PDF	N/A	Identification of regulatory promoter sequences directing MtCP6 transcription at the onset of nodule senescence in Medicago truncatula.
人工智能对蛋白质结构的建模能否区分传感器和辅助NLR免疫受体？	Toghani, A.	PDF	N/A	Can AI modelling of protein structures distinguish between sensor and helper NLR immune receptors?
单细胞代谢振荡普遍存在，可能有助于缓解蛋白质组约束。	Wongprommoon, A.	PDF	N/A	Single-cell metabolic oscillations are pervasive and may alleviate a proteome constraint
额极皮层刺激导致反事实加工的长期中断：来自局部场电位变化的见解	Ainsworth, M.	PDF	N/A	Frontopolar cortex stimulation induces prolonged disruption to counterfactual processing: insights from altered local field potentials
阅读习得促使语言跨模态在左腹侧枕颞皮层中的融合	Debska, A.	PDF	N/A	Reading Acquisition Drives Linguistic Cross-Modal Convergence in The Left Ventral Occipitotemporal Cortex
在成年早产小鼠的感觉皮层和前额叶皮层中，对行为显著线索的类似青少年的处理方式	McCoy, E.	PDF	N/A	Adolescent-like Processing of Behaviorally Salient Cues in Sensory and Prefrontal Cortices of Adult Preterm-Born Mice
人类视觉皮层中概念流形的几何结构变异	St-Yves, G.	PDF	N/A	Variation in the geometry of concept manifolds acrosshuman visual cortex
CalliCog：一个用于自由行为非人灵长类的开源认知神经科学工具包	Scott, J.	PDF	N/A	CalliCog: an open-source cognitive neuroscience toolkit for freely behaving nonhuman primates
量化存储在突触连接中的信息，而非神经网络的放电模式	Fan, X.	PDF	N/A	Quantifying information stored in synaptic connections rather than in firing patterns of neural networks
通过内部感觉预测的持续学习，建模对改变的感觉反馈的语音适应	Elie, B.	PDF	N/A	Modeling speech adaptation to altered sensory feedback through continuous learning of internal sensory predictions
气质特质的神经行为相关性：基于气质与性格量表及功能性磁共振成像选择任务的见解	Abbasi Sisara, M.	PDF	N/A	Behavioral and Neural Correlates of Temperament Traits: Insights from Temperament and Character Inventory and fMRI-Based Choice Tasks
塑造发育中的小人：感觉重映射中剥夺与补偿行为的作用	Tucciarelli, R.	PDF	N/A	Shaping the developing homunculus: the roles of deprivation and compensatory behaviour in sensory remapping
皮层组装体支持快速放电的人类PVALB+皮层中间神经元的发育，并揭示了与精神分裂症相关的缺陷。	Walsh, R. M.	PDF	N/A	Cortical assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects
元认知内省改变了决策前神经证据积累的动力学	Dou, W.	PDF	N/A	Metacognitive Introspection Alters the Dynamics of Pre-Decisional Neural Evidence Accumulation
在自然视觉中，观察到的动作的行为相关特征在皮层表征的几何结构中占据主导地位。	Han, J.	PDF	N/A	Behaviorally-relevant features of observed actions dominate cortical representational geometry in natural vision
成人嗅球解剖、组织学及超微结构：血管及淀粉样小体评估	Raspeno-Garcia, J.	PDF	N/A	Anatomy, histology and ultrastructure of the adult human olfactory peduncle: blood vessel and corpora amylacea assessment
你的记忆宫殿有多坚固？可靠的房间表征预示着随后放置物品的恢复	Masis-Obando, R.	PDF	N/A	How sturdy is your memory palace? Reliable room representations predict subsequent reinstatement of placed objects
神经遗传学证据表明，Lgr3阳性生长控制中间神经元在果蝇中表现出振荡行为	Zanini, R.	PDF	N/A	Neurogenetic evidence for oscillatory behavior of Lgr3-positive growth control interneurons in Drosophila
跨感觉切换的神经机制：延迟感觉处理和增加认知努力的证据	Vanneau, T.	PDF	N/A	Neural Mechanisms of Intersensory Switching: Evidence for Delayed Sensory Processing and Increased Cognitive Effort
在个体水平的功能梯度分析中，普罗克鲁斯特斯对齐法	Sasse, L.	PDF	N/A	Procrustes Alignment in Individual-level Analyses of Functional Gradients
纵向结构磁共振脑影像配准刚体配准算法比较研究	Rezaee Jouryabi, Y.	PDF	N/A	A comparative study of rigid-body registration algorithms for the alignment of longitudinal structural MRI of the brain
APP NL-G-F小鼠内侧内嗅皮层中的空间编码受损和神经元过度活跃	Rodriguez, G. A.	PDF	N/A	Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of APP NL-G-F mice
嗜酸性粒细胞促进单核细胞向巨噬细胞分化及抗菌免疫	Wilson, G. J.	PDF	N/A	Eosinophils promote monocyte to macrophage differentiation and anti-bacterial immunity
中性粒细胞趋化因子CXCL5在急性肺损伤中诱导肺屏障通透性	Berger, S.	PDF	N/A	Neutrophil-chemoattractant CXCL5 induces lung barrier permeability in acute lung injury
增强的艰难梭菌TcdB疫苗与合成双TLR配体佐剂联合使用的免疫原性。	Naz, F.	PDF	N/A	Enhanced immunogenicity of a Clostridioides difficile TcdB vaccine adjuvanted with a synthetic dual-TLR ligand adjuvant.
MCUB依赖性抑制线粒体钙摄取的机制	Rai, N. K.	PDF	N/A	Mechanism of MCUB-dependent inhibition of mitochondrial calcium uptake
环节动物视角下FGF信号在尾部再生中的作用	Shalaeva, A. Y.	PDF	N/A	Annelid perspectives into the role of FGF signaling in caudal regeneration
整合体复合物通过全局调控转录延伸，防止神经元过早分化。	Somsen, H. B.	PDF	N/A	The Integrator complex prevents premature neuronal differentiation through global control of transcription elongation.
性染色体塑造了植入前小鼠胚胎的转录景观	Snell, D. M.	PDF	N/A	Sex chromosomes shape the transcriptional landscape of the preimplantation mouseembryo
尽管与膜翅目昆虫存在进化上的相似性，但从蟑螂到白蚁的社会性进化过程中，监管复杂性有所降低。	Jones, A.	PDF	N/A	Reduced regulatory complexity associated with the evolutionary transition to sociality from cockroaches to termites despite evolutionary parallels with Hymenoptera
翻译上游区域的快速降解表明翻译起始过程效率低下。	Tress, M. L.	PDF	N/A	The rapid degradation of translated upstream regions points to an inefficient translation initiation process
颜色变化作为免疫能力权衡假说预测的权衡的替代解决方案	Sacchi, R.	PDF	N/A	Colour morphs as alternative solutions to the trade-off predicted by the Immuno-Competence Handicap Hypothesis
秀丽隐杆线虫可靠的气味感知与可变的联想学习	Tasnim, S.	PDF	N/A	Reliable odorant sensing but variable associative learning in C. elegans
量子关联在工程化磁敏荧光蛋白中的应用使活细胞内实现多模态传感成为可能	Abrahams, G. J.	PDF	N/A	Quantum Correlations in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells
从头组装的数据库使得无需事先了解群落组成，即可对微生物群进行基于物种特异性蛋白质的稳定同位素探针研究。	Klaes, S.	PDF	N/A	De novo assembled databases enable species-specific protein-based stable isotope probing of microbiomes without prior knowledge of the community composition
深度学习揭示了对抗肺炎克雷伯菌的潜在抗生素耐药药物	Lin, P.	PDF	N/A	Deep Learning Unravels Potential Antibiotic-Resistance Drugs against Klebsiella Pneumoniae
易患炎症性肠病会促进小鼠模型中ATF6驱动的结肠癌发生侵袭性癌变。	Kövilein, J.	PDF	N/A	Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer
利用机器学习识别特发性肺纤维化与肺鳞状细胞癌之间分子网络的差异	Nojima, Y.	PDF	N/A	Identification of the differences in molecular networks between idiopathic pulmonaryfibrosis and lung squamous cell carcinoma using machine learning
皮质神经活动在应对机械性扰动时的反应：手偏好和使用手的影响	Hooks, K.	PDF	N/A	Cortical neural activity during responses to mechanical perturbation: Effects of hand preference and hand used
在慢性暴饮酒精后的戒断和长期戒断期间，小胶质细胞促进神经退行性和过度兴奋。	McNair, E.	PDF	N/A	Microglia promote neurodegeneration and hyperkatifeia during withdrawal and prolonged abstinence from chronic binge alcohol
一种用于θ节律采样的通用过程，可以对环境信息或内部存储信息进行采样。	Fiebelkorn, I. C.	PDF	N/A	A domain-general process for theta-rhythmic sampling of either environmental information or internally stored information
眶额皮层和前扣带皮层亚区在决策与脑-体调节中的功能二分法	Papageorgiou, G. K.	PDF	N/A	Functional Dichotomy of Orbitofrontal Cortex and Anterior Cingulate Cortex Subregions in Decision-Making and Brain-Body Regulation
处理双关幽默中的负面词汇：混合情感的动态表现，融合了娱乐性与消极性	Sun, Y.	PDF	N/A	Processing negative words in pun-humor: dynamic representation of mixed feelings blending amusement and negativity
通过PARG99选择性抑制细胞质中的PARylation：一种针对FUS相关神经退行性变的靶向方法	Kodavati, M.	PDF	N/A	Selective Inhibition of Cytosolic PARylation via PARG99: A Targeted Approach for Mitigating FUS-associated Neurodegeneration
通过体内邻近标记技术揭示视网膜神经元中的电突触蛋白质组	Tetenborg, S.	PDF	N/A	Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling
学习和可塑性信号诱导突触线粒体中的极化ATP合酶	Hu, Y.	PDF	N/A	Polarized ATP synthase in synaptic mitochondria induced by learning and plasticity signals
耳念珠菌氧化应激反应相关过氧化物酶Tsa1b作为一种毒力因子，促进感染。	Areitio, M.	PDF	N/A	The oxidative stress response-related peroxiredoxin Tsa1b of Candida auris functions as a virulence factor that promotes infection
鉴定出EcpK，一种对粘细菌Myxococcus xanthus中胞外多糖生物合成至关重要的细菌酪氨酸假激酶	Bloecher, L.	PDF	N/A	Identification of EcpK, a bacterial tyrosine pseudokinase important for exopolysaccharide biosynthesis in Myxococcus xanthus
多个冗余的羧酸转运蛋白支持恶性疟原虫线粒体代谢	Prigge, S. T.	PDF	N/A	MULTIPLE, REDUNDANT CARBOXYLIC ACID TRANSPORTERS SUPPORT MITOCHONDRIAL METABOLISM IN PLASMODIUM FALCIPARUM
当代H3N2病毒受体结合域中的上位性，这些病毒已回复为结合唾液酸化二乳糖胺重复序列	Liang, R.	PDF	N/A	Epistasis in the receptor binding domain of contemporary H3N2 viruses that reverted to bind sialylated diLacNAc repeats
细菌RNA中假尿苷的定量图谱	Sharma, S.	PDF	N/A	Quantitative mapping of pseudouridines in bacteria RNA
MdfA和ClpCP介导的发育调控蛋白水解在枯草芽孢杆菌孢子形成过程中的代谢分化中起作用	Riley, E. P.	PDF	N/A	Developmentally-regulated proteolysis by MdfA and ClpCP mediates metabolic differentiation during Bacillus subtilis sporulation
肠球菌细胞壁的重塑通过释放肠球菌多糖抗原（EPA）来支撑其致病性。	Smith, R. E.	PDF	N/A	Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA)
生长速率调控酿酒酵母中RNA聚合酶II的转录延伸	Garrido-Godino, A. I.	PDF	N/A	Growth rate regulates RNA polymerase II transcription elongation in Saccharomyces cerevisiae
COVID-19疾病严重程度与T细胞受体库之间的关联	Chen, X.	PDF	N/A	Association between COVID-19 Disease Severity and T Cell Receptor Repertoire
编程群体组成和多细胞形态的综合比率计算	An, B.	PDF	N/A	Synthetic ratio computation for programming population composition and multicellular morphology
高分辨率分析揭示了转基因的转录和翻译调控的耦合机制。	Peterman, E. L.	PDF	N/A	High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes
基于大肠杆菌的无细胞系统中苹果酸的碳节约型生物生产	Cardiff, R.	PDF	N/A	Carbon-conserving Bioproduction of Malate in an E. coli-based Cell-Free System
在日本发现异源四倍体杂种物种黑曲霉	Shibata, S.	PDF	N/A	Discovery of allodiploid hybrid species Aspergillus latus in Japan
罗非鱼湖病毒核蛋白与RNA结合的结构	Arragain, B.	PDF	N/A	Structure of the Tilapia lake virus nucleoprotein bound to RNA
果糖诱发代谢功能障碍的倾向取决于基线饮食、饮食暴露的时间长度以及小鼠的性别。	Fadhul, T.	PDF	N/A	The propensity of fructose to induce metabolic dysfunction is dependent on the baseline diet, length of the dietary exposure, and sex of the mice.
拟南芥PRMT5通过缓冲供体剪接位点的遗传变异，调节前体mRNA剪接和发育	Beckel, M. S.	PDF	N/A	Arabidopsis PRMT5 Buffers Pre-mRNA Splicing and Development Against Genetic Variation in Donor Splice Sites
从700,000生物银行参与者中探究DNA重复扩展的原因和后果	Hujoel, M. L. A.	PDF	N/A	Insights into the causes and consequences of DNA repeat expansions from 700,000 biobank participants
启动子与关键的压力相关转录因子结合，以调控压力应答基因簇。	Malfait, J.	PDF	N/A	Epromoters bind key stress-related transcription factors to regulate clusters of stress response genes
# BioRxiv 2024-11-25 Papers

标题	作者	PDF链接	代码仓库	Title
解决方案结构和突触分析揭示了双特异性T细胞衔接子效力的决定因素	Leithner, A.	PDF	N/A	Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency
解构富营养化与自然变异对法国沿海潟湖大型底栖生物群落的影响	Jones, A. G.	PDF	N/A	Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons
患者差异对肾素-血管紧张素系统影响的数学建模及其在COVID-19肺纤维化结果中的应用	Islam, M. A.	PDF	N/A	Mathematical Modeling of Impacts of Patient Differences on Renin-Angiotensin System and Applications to COVID-19 Lung Fibrosis Outcomes
在转基因烟草植物从烟草蚀纹病毒感染中恢复期间，胼胝质在胞间连丝处的沉积表明其在病毒移动限制中起作用。	Vargas-Mejia, P.	PDF	N/A	Callose deposition at plasmodesmata suggests a role in viral movement restriction in transgenic tobacco plants during recovery from Tobacco etch virus infection
轻度多动症有益吗？在整个人口中，大脑的临界性在多动症症状评分处于中间水平时达到峰值。	Haque, H.	PDF	N/A	Is mild ADHD beneficial? Brain criticality peaks at intermediate ADHD symptom scores across the population
复杂性状遗传学中建模上下文依赖性的权衡	Weine, E.	PDF	N/A	Tradeoffs in Modeling Context Dependency in Complex Trait Genetics
多巴胺能神经元中食欲素受体1型缺乏增加新奇诱导的 locomotion 和探索	Xiao, X.	PDF	N/A	Deficiency of Orexin Receptor Type 1 in Dopaminergic Neurons Increases Novelty-Induced Locomotion and Exploration
肿瘤相关巨噬细胞的抗原呈递促使肿瘤浸润T细胞从原初耗竭状态转变为终末耗竭状态。	Waibl Polania, J.	PDF	N/A	Antigen presentation by tumor-associated macrophages drives tumor-infiltrating T cells from a progenitor exhaustion state to terminal exhaustion
bamSliceR：一个用于快速跨队列变异分析的Bioconductor包	Huang, Y. P.	PDF	N/A	bamSliceR: a Bioconductor package for rapid, cross-cohort variant analysis
贴纸-间隔物能量的分离控制了亚稳态凝聚物的聚结	Chattaraj, A.	PDF	N/A	Separation of sticker-spacer energetics governs the coalescence of metastable condensates
肝窦内皮细胞构成了血红蛋白清除的主要途径。	Zurawska, G.	PDF	N/A	Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance
解析NAP-CNB机器学习增强型肿瘤新抗原预测的力量	Mendez-Perez, A.	PDF	N/A	Unraveling the Power of NAP-CNB's Machine Learning-enhanced Tumor Neoantigen Prediction
研究地钱（Marchantia polymorpha）中的顶端切口、顶端优势及分生组织再生的现象。	Marron, A. O.	PDF	N/A	Investigating the apical notch, apical dominance and meristem re-emergence in Marchantia polymorpha.
ELF3-BBX24/BBX25-PIF4模块控制拟南芥的热感应生长	Malakar, B. C.	PDF	N/A	The ELF3-BBX24/BBX25-PIF4 module controls thermosensory growth in Arabidopsis
时间注意在中间处理阶段增强了前扣带回皮层的刺激信息	Zhu, J.	PDF	N/A	Temporal attention amplifies stimulus information in fronto-cingulate cortex at an intermediate processing stage
投射至腹侧CA1区的内梨状神经元是识别记忆的关键节点。	Yamawaki, N.	PDF	N/A	Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory
自噬蛋白ATG14通过防止非计划性的细胞焦亡激活，从而在早期妊娠期间保障胚胎运输。	POPLI, P.	PDF	N/A	The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy
开发无细胞平台以发现、表征和工程化翻译后修饰	Wong, D. A.	PDF	N/A	Development of cell-free platforms for discovering, characterizing, and engineering post-translational modifications
呼吸暂停突显了小鼠的睡眠结构	Casali, G.	PDF	N/A	Respiratory pauses highlight sleep architecture in mice
通过物种相互作用在生物多样性实验中划分生态系统生产力的变化	Tao, J.	PDF	N/A	Partitioning changes in ecosystem productivity by effects of species interactions in biodiversity experiments
ROS诱导的压力促进抗生素抗性在传统活性污泥工艺中的富集和出现	Manna, B.	PDF	N/A	ROS-Induced Stress Promotes Enrichment and Emergence of Antibiotic Resistance in Conventional Activated Sludge Processes
RuBisCO的进化动力学：小亚基的出现及其随时间的演变影响	Amritkar, K.	PDF	N/A	Evolutionary Dynamics of RuBisCO: Emergence of the Small Subunit and its Impact Through Time
撤回：揭示亲炎性巨噬细胞在先兆子痫母胎界面免疫网络失衡中的关键作用	Fei, H.	PDF	N/A	WITHDRAWN: Unveiling the Crucial Role of Pro-inflammatory Macrophages in the Immune Network Imbalance of the maternal-fetal interface with Preeclampsia
溶酶体信号通路影响心脏节律，并调节心房功能。	Capel, R. A.	PDF	N/A	Lysosomal signalling pathways influence heart rhythm, and regulate atrial function
多组学分析与机器学习预测：在存在配子和胚胎的情况下输卵管的反应	Finnerty, R. M.	PDF	N/A	Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos
成人颞叶新皮层第1层兴奋性突触小体的超微结构亚层特异性多样性	Rollenhagen, A.	PDF	N/A	Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex
脂肪组织中的芳香化酶通过磷酸盐调节在雄性小鼠中发挥骨保护作用。	Ikedo, A.	PDF	N/A	Aromatase in adipose tissue exerts an osteoprotective function in male mice via phosphate regulation
果蝇（Drosophila melanogaster）中的化学配偶选择模仿	Mitchell, B.	PDF	N/A	Chemical mate choice copying in Drosophila melanogaster
发现了一种新型鞭虫物种，即T. incognita，其在科特迪瓦患者中对阿苯达唑-伊维菌素治疗的敏感性较低，通过粪便DNA代谢条形码技术鉴定。	Venkatesan, A.	PDF	N/A	Discovery of a novel Trichuris species, T. incognita, with low sensitivity to albendazole-ivermectin treatment in Cote d'Ivoire patients, identified through fecal DNA metabarcoding
细胞分裂素作为系统信号，协调拟南芥的生殖努力。	Volkava, D.	PDF	N/A	Cytokinin acts as a systemic signal coordinating reproductive effort in Arabidopsis
一个动力学简单行走模型修正了恢复速率的定义	Hosseini-Yazdi, S.-S.	PDF	N/A	A Powered Simple Walking Model Modifies the Rate of Recovery Definition
小鼠脑中七个kisspeptin能神经元群体的综合化学分型和性腺调控	Hernandez, V. S.	PDF	N/A	A comprehensive chemotyping and gonadal regulation of seven kisspeptinergic neuronal populations in the mouse brain
HIV-1 Vif破坏了动粒处的磷酸酶反馈调节，导致明显的伪中期停滞	Ghone, D.	PDF	N/A	HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest
大西洋沟虾（Palaemon varians Leach, 1814）的蜕皮周期与刚毛发育（十足目：真虾下目：长臂虾科）	Kim, K.	PDF	N/A	Moult cycle and setal development of the Atlantic ditch shrimp Palaemon varians Leach, 1814 (Decapoda: Caridea: Palaemonidae)
胆碱能信号对鸣禽的鸣唱前运动回路进行差异化调控，以稳定鸣唱。	Xu, N.	PDF	N/A	Cholinergic signaling differentially regulates song premotor circuits to stabilize songs in songbirds
人类CCR4-NOT全局调控基因表达，是一种新型逆转录转座子激活的沉默因子。	Kulkarni, S.	PDF	N/A	Human CCR4-NOT globally regulates gene expression and is a novel silencer of retrotransposon activation
调控因子的反相聚集塑造基因爆发	Li, B.	PDF	N/A	Anti-phase clustering of regulatory factors shapes gene bursting
化石多样化速率的明显时间尺度变化是由抽样偏差引起的。	Reijenga, B. R.	PDF	N/A	Apparent timescaling of fossil diversification rates is caused by sampling bias
海马结构中社会知识的自我中心锚定与调整	Rodriguez Aramendia, M.	PDF	N/A	Egocentric anchoring-and-adjustment of social knowledge in the hippocampal formation
编码于自我扩增RNA中的广谱免疫抑制作用能够实现非细胞毒性、非免疫刺激性的可逆转基因表达。	Lim, T. K. Y.	PDF	N/A	Broad-spectrum immune suppression encoded inself-amplifying RNA enables non-cytotoxic, non-immunostimulatory, reversible transgene expression
编码于自我扩增RNA中的广谱免疫抑制作用能够实现非细胞毒性、非免疫刺激性的可逆转基因表达。	Lim, T. K. Y.	PDF	N/A	Broad-spectrum immune suppression encoded in self-amplifying RNA enables non-cytotoxic, non-immunostimulatory, reversible transgene expression
疟原虫裂殖子单细胞RNA测序揭示，寄生虫通过激活基因网络为进入红细胞做准备。	Piel, L.	PDF	N/A	Single cell RNA-sequencing of malaria merozoites reveals that the parasite prepares for life within the red blood cell by activating a gene network
撤回：来自登革病毒2型感染的血管内皮细胞的灭活条件培养基对上皮细胞愈合的影响：活细胞成像分析。	Hincapie, V.	PDF	N/A	WITHDRAWN: Effect of inactivated conditioned media from DENV-2-infected endothelial cells on epithelial cell healing: live cell imaging analysis.
芜菁黄化病毒颗粒的结构。读取穿透域是如何暴露在衣壳表面的？	Lai-Kee-Him, J.	PDF	N/A	Structure of the turnip yellows virus particles. How is the readthrough domain exposed on the capsid surface?
前膜和包膜蛋白对蜱传脑炎病毒结构、致病性和趋向性的影响	Rosendal, E.	PDF	N/A	The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus
非裂解性复制病毒递送IL15超级激动剂增强抗肿瘤免疫并延长胶质母细胞瘤生存期	Haddad, A. F.	PDF	N/A	Non-lytic replicating viral delivery of an IL15 superagonist enhances antitumor immunity and extends survival in glioblastoma
光流解析作为因果源分离：一种从光流中同时提取物体和自身运动信息的计算模型	Scherff, M.	PDF	N/A	Flow parsing as causal source separation: A computational model for concurrent retrieval of object and self-motion information from optic flow
细菌双组分信号传导网络中激酶和效应子信号传导逻辑的变化	Swingle, D.	PDF	N/A	Variations in kinase and effector signaling logic in a bacterial two component signaling network
大规模定量交联质谱技术揭示了细胞器、细胞和组织中蛋白质构象可塑性的新见解	Keller, A.	PDF	N/A	Large-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues
SARM1激活通过两步液-固相变促进轴突退化	Zhang, W.	PDF	N/A	SARM1 Activation Promotes Axonal Degeneration Via a Two-Step Liquid-to-Solid Phase Transition
网格蛋白通过共同维持高尔基体的结构-功能关系来支持细胞外基质分泌。	Thompson, G.	PDF	N/A	Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship
溶组织内阿米巴中富含谷氨酸-赖氨酸（EK）的RabD2基序通过自相互作用及多泡体途径调控病原体的发病机制	Navyaka, P.	PDF	N/A	Glutamic acid-lysine (EK) rich motif of RabD2 self-associates and regulates pathogenesis through multivesicular bodies pathway in E. histolytica
ALS和FTD相关蛋白Annexin A11和CHMP2B在膜修复中依次发挥作用	Heffner, C. M.	PDF	N/A	The ALS- and FTD-associated proteins Annexin A11 and CHMP2B act sequentially in membrane repair
迈向鲁棒机器嗅觉：去偏GC-MS数据提升前列腺癌从尿液挥发性物质中的诊断	Rotteveel, A.	PDF	N/A	Towards robust machine olfaction: debiasing GC-MS data enhances prostate cancer diagnosis from urine volatiles
细菌类泛素蛋白的结构多样性与寡聚化	Gong, M.	PDF	N/A	Structural diversity and oligomerization of bacterial ubiquitin-like proteins
微生物物种树重建的系统评估方法	Weiner, S.	PDF	N/A	A systematic assessment of phylogenomic approaches for microbial species tree reconstruction
Ezh2在正常小脑颗粒神经元发育过程中延迟分化基因的激活，并在髓母细胞瘤中发挥类似作用。	Purzner, J.	PDF	N/A	Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma
在一种分化的细菌泛素化途径中蛋白质共轭的机制基础	Ye, Q.	PDF	N/A	Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway
计算分析以评估降主动脉瘤中的血流动力学力	Duca, F.	PDF	N/A	Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms
在非常罕见的祖B细胞条件下，多样化的启动结果	Madden, P. J.	PDF	N/A	Diverse priming outcomes under conditions of very rare precursor B cells
成对相互作用和连续瓶颈效应有助于解释多物种微生物群落中的物种组成	Lele, K.	PDF	N/A	Pairwise interactions and serial bottlenecks help explain species composition in a multi-species microbial community
具有两种不同DNA结合模式的保守ComP结构——使用AlphaFold3、RoseTTAFold2NA、Chai-1进行系统建模及在HADDOCK中重新对接	Helsem, S. A.	PDF	N/A	The conserved ComP structure with two distinct DNA binding modes - systematic modeling with AlphaFold3, RoseTTAFold2NA, Chai-1 and re-docking in HADDOCK
一种偏好腺嘌呤碱基编辑器，具有最小的旁观者效应和脱靶编辑	Shang, M.	PDF	N/A	A motif preferred adenine base editor with minimal bystander and off-targets editing
抗生素治疗和微生物群减少会减缓刺胞动物的再生过程。	Da-Anoy, J.	PDF	N/A	Antibiotic treatment and microbiome depletion slow cnidarian regeneration
网络共同体：连接数据、知识和方法，构建和评估特定情境下的生物网络	Paton, V.	PDF	N/A	NetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological networks
复制压力标志物磷酸化-RPA2预测同源重组功能正常的卵巢癌对铂类和PARP抑制剂的反应	Schab, A.	PDF	N/A	Replication stress marker phospho-RPA2 predicts response to platinum and PARP inhibitors in homologous recombination-proficient ovarian cancer
乙型肝炎核心相关抗原在既往乙型肝炎病毒感染患者病毒基因组整合中的作用	Saito, T.	PDF	N/A	Involvement of Hepatitis B Core-Related Antigen in Viral Genome Integration in Patients With Prior Hepatitis B Virus Infection
S-1生物标志物对接受辅助S-1化疗的老年肺癌患者衰老和预后的影响：Setouchi肺癌研究组1201研究的伴随结果	Soh, J.	PDF	N/A	Implication of S-1 biomarkers on aging and prognosis in elderly patients with lung cancer treated by adjuvant S-1 chemotherapy: Accompanying results of the Setouchi Lung Cancer Group Study 1201
细胞代谢通量分布的深度学习预测寿命	Hilsabeck, T. A.	PDF	N/A	Deep Learning of Cellular Metabolic Flux Distributions Predicts Lifespan
多巴胺在有无反馈的情况下都会影响运动学习表现。	Leow, L.-A.	PDF	N/A	Dopamine alters motor learning performance in the presence and absence of feedback
GRNIX：一种基于图神经网络的可解释基因调控网络推断框架，用于自身免疫性疾病中的XAI	Manai, M. M.	PDF	N/A	GRNIX: A Graph Neural Network Framework for Explainable Gene Regulatory Network Inference in Autoimmune Diseases Using XAI
改进的深度学习预测TCR-HLA关联	Li, F.	PDF	N/A	Improved Deep Learning Prediction of TCR-HLA Association
间隙DNA的序列依赖性液晶有序化	Kodikara, S.	PDF	N/A	Sequence-Dependent Liquid Crystalline Ordering of Gapped DNA
高度有序脂质双层中玻璃态动力学的特征及软动态通道的出现	Sureshkumar, H.	PDF	N/A	Signatures of glassy dynamics in highly ordered lipid bilayers with emergence of soft dynamic channels
基于荧光技术的活细胞成像识别出跳过第14外显子的肝细胞生长因子受体（MET）降解剂	Mallareddy, J. R.	PDF	N/A	Fluorescence based live cell imaging identifies exon 14 skipped hepatocyte growth factor receptor (MET) degraders
中国上二叠统闹包沟组四足动物群：一种新的中型前棱蜥类——阴山龙属新种阴山龙及其对前棱蜥类系统发育关系的启示	Yi, J.	PDF	N/A	The tetrapod fauna of the upper Permian Naobaogou Formation of China: a new mid-sized pareiasaur Yinshanosaurus angustus gen. et sp. nov. and its implication for the phylogenetic relationship of pareiasaurs
TGFbeta-LRRC15轴的关键调控元件预测了多种癌症类型的疾病进展及免疫治疗抵抗	Storey, C. M.	PDF	N/A	Key Regulatory Elements of the TGFbeta-LRRC15 Axis Predict Disease Progression and Immunotherapy Resistance Across Cancer Types
玉米黑粉菌（Ustilago maydis）通过破坏宿主细胞中的碳水化合物信号网络来诱导细胞肥大。	Lee, Y. J.	PDF	N/A	Ustilago maydis disrupts carbohydrate signaling networks to induce hypertrophy in host cells
适应性生物系统的累积剂量反应	Gupta, A.	PDF	N/A	Cumulative dose responses for adapting biological systems
鱼类微小RNA对热应激的响应：全球变暖背景下对水产养殖与保护的启示与影响	Lin, T.	PDF	N/A	Fish MicroRNA Responses to Thermal Stress: Insights and Implications for Aquaculture and Conservation Amid Global Warming
大脑-网格模型：神经同步、可塑性和一致性的统一框架	Ballus, A.	PDF	N/A	THE BRAIN-MESH MODEL: A UNIFIED FRAMEWORK FORNEURAL SYNCHRONY, PLASTICITY, AND COHERENCE
人类大脑区域脑熵（BEN）的细胞类型基础	Song, D.	PDF	N/A	The cell-type underpinnings of regional brain entropy (BEN) in human brain
通过纵向分子亚型分析揭示SARS-CoV-2宿主反应的异质性	Wang, K.	PDF	N/A	Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping
唐氏综合征中失调的气道上皮抗病毒免疫削弱了III型干扰素反应，并在呼吸道合胞病毒感染期间加剧了气道炎症。	Chorvinsky, E.	PDF	N/A	Dysregulated airway epithelial antiviral immunity in Down Syndrome impairs type III IFN response and amplifies airway inflammation during RSV infection.
肠道损伤的新型免疫标志物，指示HIV-1状态和/或亚临床动脉粥样硬化	Moreira Gabriel, E.	PDF	N/A	Novel Immunological Markers of Intestinal Impairment Indicative of HIV-1 Status and/or Subclinical Atherosclerosis
Bin Chicken：针对目标宏基因组共组装，高效恢复新颖基因组	Aroney, S. T. N.	PDF	N/A	Bin Chicken: targeted metagenomic coassembly for the efficient recovery of novel genomes
RetS通过感知神经递质去甲肾上腺素和肾上腺素来调节铜绿假单胞菌的毒力。	Zhou, Y.	PDF	N/A	RetS senses neurotransmitter norepinephrine and adrenergic agents to regulate Pseudomonas aeruginosa virulence
益生菌搅拌酸奶对大鼠代谢功能障碍相关脂肪肝疾病的预防作用	Sallam, M. S.	PDF	N/A	Probiotic Stirred Yogurt Mediated the Prevention of Metabolic Dysfunction-Associated Steatotic Liver Disease in Rats
在GKAP支架蛋白与LC8枢纽蛋白之间拓扑约束的多价复合物中，存在残余的灵活性。	Nagy-Kanta, E.	PDF	N/A	Residual flexibility in the topologically constrained multivalent complex between the GKAP scaffold and LC8 hub proteins
细菌硫辛酰胺蛋白连接酶在哺乳动物中拯救硫辛酰化及呼吸缺陷	Hu, Z.	PDF	N/A	Bacterial lipoate protein ligases rescue lipoylation and respiration deficiency in mammals
全球微型浮游生物生物地理分布通过宏基因组和气候数据整合揭示	Salazar, V. W.	PDF	N/A	Global picoplankton biogeography revealed by metagenomic and climatic data integration
委内瑞拉三种空中捕食蝙蝠的饮食及其生态位划分	Azofeifa Romero, Y.	PDF	N/A	Diet and trophic niche partitioning of three aerial hawking bat species in Venezuela
使用堆叠模型和物种特征预测食物网中的缺失链接	Van Kleunen, L. B.	PDF	N/A	Predicting missing links in food webs using stacked models and species traits
基于三联体（triplet）的物种树估算方法对基因树根节点（或其缺失）的鲁棒性	Zaman, T. A.	PDF	N/A	On the robustness to gene tree rooting (or lack thereof) of triplet-based species tree estimation methods
单花蝇子草的染色体规模基因组组装和连锁图谱揭示了快速进化植物物种的重组景观	Osborne, O. G.	PDF	N/A	Chromosome-scale genome assembly and linkage map for Silene uniflora reveal the recombination landscape in a rapidly evolving plant species
果蝇（Drosophila melanogaster）中高度转录且具有性别偏向基因的非最优密码子选择的证据	Whittle, C. A.	PDF	N/A	Evidence for non-optimal codon choice in highly transcribed sex-biased genes of Drosophila melanogaster
综合方法优先考虑孤儿GPR61基因组区域在组织特异性调节生物钟类型中的作用	Tchio, C.	PDF	N/A	An integrative approach prioritizes the orphan GPR61 genomic region in tissue-specific regulation of chronotype
肌萎缩侧索硬化症中的性别特异性DNA甲基化差异	Grant, O.	PDF	N/A	Sex-specific DNA methylation differences in Amyotrophic lateral sclerosis
潜在抑制、发散思维与目击记忆的关系：一项关于对无关刺激注意的研究	Badiola-Lekue, I.	PDF	N/A	The Relationship between Latent Inhibition, Divergent Thinking, and Eyewitness Memory: A Study on Attention to Irrelevant Stimuli
通过活性位点半胱氨酸对SARS-CoV-2 NiRAN结构域进行共价抑制	Hernandez, G.	PDF	N/A	Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine
印楝油纳米乳剂对人类神经母细胞瘤SH-SY5Y细胞系中由淀粉样β1-40诱导的抗阿尔茨海默病效应	Govindaswamy, B.	PDF	N/A	Anti Alzheimer's effects of Neem oil nanoemulsion against Amyloid β1-40 induced in human neuroblastoma SH-SY5Y cell line
兔心生物人工组织：灌注去细胞化与特性分析	Seitzhaparova, B.	PDF	N/A	Rabbit Heart Bioartificial Tissue: Perfusion Decellularization and Characterization
评估用于病毒基因组学的长读长映射工具	Baudeau, T.	PDF	N/A	Assessing Long-Read Mappers for Viral Genomics
CNV-Profile回归：一种新的全基因组测序数据拷贝数变异关联分析方法	Si, Y.	PDF	N/A	CNV-Profile Regression: A New Approach for Copy Number Variant Association Analysis in Whole Genome Sequencing Data
解剖区域特异性转录组特征及上皮细胞在翼状胬肉炎症中的作用：一项多组学分析	Song, C.	PDF	N/A	Anatomical Region-Specific Transcriptomic Signatures and the Role of Epithelial Cells in Pterygium Inflammation: A Multi-Omics Analysis
利用眼动持续同调性进行神经障碍筛查	He, D.	PDF	N/A	Leveraging Persistent Homology of Eye Movements for Neural Disorder Screening
通过计算机模拟和RBP结合的解释，揭示了m6A-RBP相互作用	Liu, J.	PDF	N/A	In-silico modeling and interpretation of RBP binding disentangle m6A-RBP interaction
用于通过光学控制跨膜离子通信的开关纳米孔	Wang, X.	PDF	N/A	ON-OFF nanopores for optical control of transmembrane ionic communication
Tau聚集受其投影域突变的影响而发生改变	Mason-Chalmers, K.	PDF	N/A	Tau Aggregation is Altered by Mutations in its Projection Domain
腹水可防止铁死亡并促进卵巢癌的腹腔扩散	Setayeshpour, Y.	PDF	N/A	Ascitic fluid protects against ferroptosis and enables the peritoneal spread of ovarian cancer
FAK抑制通过DNA甲基化介导的DAB2基因重新激活抑制乳腺癌进展	Lim, S.	PDF	N/A	FAK inhibition suppresses breast cancer progression via DNA methylation-mediated DAB2 gene reactivation
抑制Wnt通路效应因子TCF7L2可逆转小鼠肠道癌症中的致命恶病质	Leong, M. L.	PDF	N/A	Repression of the Wnt pathway effector TCF7L2 reverses lethal cachexia in mice with intestinal cancers
定量磁共振成像测量捕捉到胰腺癌和基质对新型KRAS抑制剂的反应	Gupta, M.	PDF	N/A	Quantitative MRI Measurements Capture Pancreatic Cancer and Stroma Reactions to New KRAS Inhibitor
豌豆白粉菌（Erysiphe pisi）是一种专性寄生真菌，主要感染豌豆（Pisum sativus）和扁豆（Lathyrus sativus）。扁豆是一种重要的粮食和饲料作物，在亚洲和非洲部分地区广泛种植。然而，扁豆对豌豆白粉菌的抗性因品种而异，这限制了其在这些地区的可持续种植。为了更好地了解扁豆对豌豆白粉菌的抗性机制，我们进行了比较转录组学分析，比较了两个扁豆品种（Ls-1和Ls-2）在接种豌豆白粉菌后的转录组变化。我们发现，两个品种在接种豌豆白粉菌后表现出不同的转录组响应，表明它们对病原体的抗性机制存在差异。具体而言，Ls-1品种在接种豌豆白粉菌后上调了多个与防御相关的基因，包括几丁质酶、β-1,3-葡聚糖酶和抗病蛋白基因，而Ls-2品种则没有表现出类似的上调。此外，我们还发现Ls-1品种在接种豌豆白粉菌后下调了多个与生长和发育相关的基因，这可能有助于将资源重新分配给防御反应。我们的研究结果表明，扁豆对豌豆白粉菌的抗性是一个复杂的性状，涉及多个基因和途径的调控。未来的研究应进一步探索这些基因和途径在扁豆抗病性中的作用，以开发更有效的抗病品种。	Marques, R. M.	PDF	N/A	Comparative transcriptomics of Lathyrus sativus reveals accession-specific resistance responses against Erysiphe pisi
通过综合生态基因组学揭示全球栗树害虫入侵的由下而上和由上而下的控制机制	Zitoun, J.-l.	PDF	N/A	Unravelling the bottom-up and top-down control of a worldwide chestnut tree pest invader through integrative ecological genomics
细胞通过进入一种类似静止的状态，以高效率转化为神经元。	Beitz, A. M.	PDF	N/A	Cells transit through a quiescent-like state to convert to neurons at high rates
三级淋巴结构作为克罗恩病治疗靶点：TNFα阻断剂的调节作用	Nagase, Y.	PDF	N/A	Tertiary lymphoid structure as a therapeutic target of Crohns disease: modulation by TNFα blockade
利用受激辐射损耗显微技术揭示活体白色念珠菌的超微结构	Baxter, K. J.	PDF	N/A	Revealing the Ultrastructure of Live Candida albicans using Stimulated Emission Depletion Microscopy
深海冷泉中的微生物毒力组和抗性组对公共健康构成的风险极小。	Zhang, T.	PDF	N/A	Microbial virulome and resistome in deep-sea cold seeps pose minimal public health risks
SARS-CoV-2 nsp1中自然发生的N端突变影响先天免疫调节，但不影响病毒毒力	Rani, R.	PDF	N/A	Naturally occurring N-terminal mutations in SARS-CoV-2 nsp1 impact innate immune modulation but do not affect virus virulence
慢性感染SARS-CoV-2患者体内遗传多样性的多种模式	Rutsinsky, N.	PDF	N/A	Diverse patterns of intra-host genetic diversity in chronically infected SARS-CoV-2 patients
多个线虫物种在整个神经系统中进化变化的分子模式	Toker, I. A.	PDF	N/A	Molecular patterns of evolutionary changes throughout the whole nervous system of multiple nematode species
解决斑纹蟾蜍（Bufonidae: Incilius marmoreus）的分类地位：基于2RAD的系统地理学研究，包括墨西哥韦拉克鲁斯州的一个孤立种群	Wang, K.	PDF	N/A	Resolving the Taxonomic Status of the Marbled Toad (Bufonidae: Incilius marmoreus): 2RAD-based Phylogeography Including an Isolated Population in Veracruz, Mexico
多个性状的协同进化使蝴蝶拥有了一个假头	Yumnam, T.	PDF	N/A	Correlated evolution of multiple traits gives butterflies a false head
全基因组关联研究确定了冬季和早春耐寒性的有希望的QTL，作为深入遗传分析和在冬蚕豆（Vicia faba L.）育种中实施的基础。	Windhorst, A.	PDF	N/A	Genome-wide association studies identify promising QTL for freezing tolerance in winter and early spring as a basis for in-depth genetic analysis and implementation in winter faba bean (Vicia faba L.) breeding
一种用于评估应用于野生海洋鱼类的基因组动物模型鲁棒性的新框架	Thia, J. A.	PDF	N/A	A novel framework for assessing the robustness of genomic animal models applied to a wild marine fish
苏门答腊猩猩母亲在母性行为的表现程度和轨迹上存在差异。	Revathe, T.	PDF	N/A	Sumatran orangutan mothers differ in the extent and trajectory of their expression of maternal behaviour
斑胸草雀社会网络多层结构的社会和空间驱动因素	Zhang, Y.	PDF	N/A	Social and spatial drivers of the multitiered structure of zebra finch social networks
对下丘脑表型的调查确定了雄性和雌性小鼠中MYT1L单倍体不足的分子和行为后果。	Dougherty, J. D.	PDF	N/A	A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice.
狐獴中的发声修饰：弱联结的从属者对支配者的回应中发出更多的叫声	Demartsev, V.	PDF	N/A	Vocal grooming in meerkats: weakly bonded subordinatescall more in response to dominants
衰老对黑猩猩使用石器工具的参与度和效率的影响因个体而异。	Howard-Spink, E.	PDF	N/A	Old age variably impacts chimpanzee engagement and efficiency in stone tool use
在体外高保真地将多种合成货物包装到封装蛋白笼中	Szyszka, T. N.	PDF	N/A	High-fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages
肝细胞癌的综合转录组分析：揭示不同病因中的共享与独特分子特征	Khorsand, B.	PDF	N/A	Comprehensive Transcriptomic Analysis of Hepatocellular Carcinoma: Uncovering Shared and Unique Molecular Signatures Across Diverse Etiologies
洛伦兹对基因集富集分析的看法：基因集富集分析与财富不平等衡量方法的相似性与差异	Pagnotta, S. M.	PDF	N/A	The Lorenz's side of Gene Set Enrichment Analysis: Similarity and divergences of the Gene Set Enrichment Analysis from the measure of wealth inequality
NhaA中Na+/H+反向转运的分子机制	Xie, T.	PDF	N/A	Molecular mechanism of Na+/H+ antiporting in NhaA
雌激素受体信号转录程序与人类激素受体阳性乳腺癌中的免疫逃逸相关	Shimada, K.	PDF	N/A	An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer
同时抑制COX-1和COX-2不足以引发与长期使用非甾体抗炎药（NSAID）相关的肠病。	Barekat, K.	PDF	N/A	Concomitant suppression of COX-1 and COX-2 is insufficient to induce enteropathy associated with chronic NSAID use
氧化性损伤对肺线粒体DNA是化学性肺损伤发展的关键因素	Dubey, S.	PDF	N/A	Oxidative Injury to Lung Mitochondrial DNA is a Key Contributorfor the Development of Chemical Lung Injury
可可基因组序列揭示了黄酮类生物合成的见解	Marin Recinos, M. F.	PDF	N/A	Cacao genome sequence reveals insights into the flavonoid biosynthesis
DNA复制时序揭示了转录和脆弱性的全基因组特征	Berkemeier, F.	PDF	N/A	DNA replication timing reveals genome-wide features of transcription and fragility
评估单细胞基因表达动力学对联合抗生素生存能力的预测能力	Alnahhas, R. N.	PDF	N/A	Evaluating the predictive power of combined gene expression dynamics from single cells on antibiotic survival
区域特异性图片命名受益于焦点tDCS的效果取决于老年人的基线表现	Yucel, A.	PDF	N/A	Regionally specific picture naming benefits of focal tDCS are dependent on baseline performance in older adults
同种社交性受联想学习回路调节。	Lobato-Rios, V.	PDF	N/A	Conspecific sociability is regulated by associative learning circuits
叶酸可预防草原田鼠因发育期接触拟除虫菊酯而导致的自闭症相关表型。	Saferin, N.	PDF	N/A	Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles
鼻内丹曲洛林纳米颗粒抑制5XFAD小鼠脑内炎症性细胞焦亡	Bhuiyan, P.	PDF	N/A	Intranasal dantrolene nanoparticles inhibit inflammatory pyroptosis in 5XFAD mice brains
Parp1缺失可挽救xrcc1突变斑马鱼的小脑发育不良	Semenova, S. A.	PDF	N/A	Parp1 deletion rescues cerebellar hypotrophy in xrcc1 mutant zebrafish
使用基于定量MRI的水参考的2D 1H-MRSI对脑代谢物进行绝对定量	Thomas, D. C.	PDF	N/A	Absolute quantification of cerebral metabolites using 2D 1H-MRSI with quantitative MRI-based water reference
一种多用途的鼠标模型，用于推进神经退行性疾病中人源小胶质细胞移植研究	De Strooper, B.	PDF	N/A	A versatile mouse model to advance human microglia transplantation research in neurodegenerative diseases
基于多模态、多方面的成像人类大脑白质图谱	Zhou, J.	PDF	N/A	Multimodal, multifaceted Imaging-based Human Brain White Matter Atlas
虚拟大脑将经颅磁刺激引发的电位与重度抑郁症中抑制性神经递质的变化联系起来。	Hofsähs, T.	PDF	N/A	The Virtual Brain links transcranial magnetic stimulation evoked potentials and inhibitory neurotransmitter changes in major depressive disorder
直观的物理推理并不通过语言进行中介，也不是仅依赖于领域通用的抽象表征。	Kean, H. H.	PDF	N/A	Intuitive physical reasoning is not mediated by linguistic nor exclusively domain-general abstract representations
使用量子点和去卷积技术的快速光稳定扩展显微镜	Gunawardhana, L.	PDF	N/A	Fast Photostable Expansion Microscopy Using QDots andDeconvolution
通过计算建模揭示了人类和猴子对三维和运动刺激的不同决策过程	Rangotis, R.	PDF	N/A	Distinct decision processes for 3D and motion stimuli in both humans and monkeys revealed by computational modelling
增加的不情愿囊泡通过GPR55在小脑浦肯野细胞轴突末梢中导致突触抑制	Inoshita, T.	PDF	N/A	Increased reluctant vesicles underlie synaptic depression by GPR55 in axon terminals of cerebellar Purkinje cells
CRISPRa介导的2C样状态、全能性和细胞死亡中Dux-MERVL轴的解离	Chammas, P.	PDF	N/A	CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency and cell death
糖基转移酶POGLUT1调控小鼠肌肉干细胞的发育和维持	Cho, S.	PDF	N/A	The glycosyltransferase POGLUT1 regulates muscle stem cell development and maintenance in mice
全面蛋白质组学、超微结构及功能分析：低温保存对海洋贻贝卵细胞的影响	Blanco, S.	PDF	N/A	Comprehensive Proteomic, Ultrastructural and Functional Analysis of Cryopreservation Effects on Marine Mussel Oocytes
城市化对芝加哥地区美洲知更鸟（Turdus migratorus）健康的影响	Riccardi, A.	PDF	N/A	Impacts of urbanization on the health of American Robins (Turdus migratorus) in Chicagoland
测试蜜蜂的峰终法则：当最终奖励令人失望时，蜜蜂对高奖励序列缺乏偏好	Armand, M.	PDF	N/A	Testing the peak-end rule in bumblebees: lack of preference for a higher-reward sequence when the final reward is disappointing
雌性小鼠超声波发声的频率较低，在与无声雄性互动时，其发声频率并不受发情状态的影响。	Malone, C. A.	PDF	N/A	Rates of female mouse ultrasonic vocalizations are low and are not modulated by estrous state during interactions with muted males
脊髓刺激模型中的频率依赖性和电容性组织电特性	Khadka, N.	PDF	N/A	Frequency-dependent and capacitive tissue electrical properties in spinal cord stimulation models
ApoDock：用于柔性分子对接的配体条件侧链包装	Luo, D.	PDF	N/A	ApoDock: Ligand-Conditioned Sidechain Packing for Flexible Molecular Docking
DeepAssembly2：基于域-域相互作用的蛋白质复合物结构组装网络服务器	Xia, Y.	PDF	N/A	DeepAssembly2: A Web Server for Protein Complex Structure Assembly Based on Domain-Domain Interactions
饥饿和荷尔蒙状态的整合调控着面向婴儿的攻击行为	Cao, M.	PDF	N/A	Integration of hunger and hormonal state gates infant-directed aggression
胚胎生成的中间神经元（EGINs）在嗅球中表现出独特的发展程序和分层结构。	Spence, N. J.	PDF	N/A	Embryonically generated interneurons (EGINs) exhibit a distinctive developmental program and lamination in the olfactory bulb
H通道和m通道的过度表达通过损害抑制性神经元处理相关输入的能力，促进了类似癫痫事件的发生。	Rich, S.	PDF	N/A	H- and m-channel overexpression promotes seizure-like events by impairing the ability of inhibitory neurons to process correlated inputs
谷氨酰胺分解促进易患狼疮小鼠的滤泡辅助性T细胞功能	Choi, S. C.	PDF	N/A	Glutaminolysis promotes the function of follicular helper T cells in lupus-prone mice
从濒危的塔斯马尼亚恶魔（Sarcophilus harrisii）肿瘤细胞中分离出一种类似病毒的传染性哺乳动物病毒	Melade, J.	PDF	N/A	Isolation of an infectious mammalian chu-like virus from tumor cells of the endangered Tasmanian devil (Sarcophilus harrisii)
细菌菌落活检：通过细胞光谱指纹技术实现异质细胞类型的空间辨别	Abbaszade, G.	PDF	N/A	Bacterial colony biopsies: spatial discrimination of heterogeneous cell types by cytometric fingerprinting
M66I衣壳变异体对Lenacapavir耐药的结构和机制基础	Briganti, L.	PDF	N/A	Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir
毒力决定因子蛋白E是一种弗朗西斯菌VI型分泌系统效应蛋白，能够调节宿主细胞的死亡。	Adams, N.	PDF	N/A	Pathogenicity determinant protein E is a Francisella type VI secretion system effector protein that modulates host death
评估宽吻海龙（Syngnathus typhle）肠道微生物群组成中噬菌体的影响	Parker, J.	PDF	N/A	Evaluating bacteriophage impact on gut microbiome composition in broad-nosed pipefish (Syngnathus typhle)
HsbA抑制铜绿假单胞菌静止期生物膜的形成。	Pulido Sanchez, M.	PDF	N/A	HsbA represses stationary phase biofilm formation in Pseudomonas putida
Rigosertib可逆转与RAF1相关的努南综合征中的肥厚型心肌病	Legler, L.	PDF	N/A	Rigosertib reverses hypertrophic cardiomyopathy in RAF1-associated Noonan syndrome
从犬类脐带中非病毒诱导的多能干细胞的衍生	Yamazaki, A.	PDF	N/A	Non-viral derivation of induced pluripotent stem cells from the canine umbilical cord
内耳神经元的脱离时间决定了它们的空间分布和目标神经支配。	Saini, S. S. J. S.	PDF	N/A	Timing of delamination of inner ear neurons specifies their topography and target innervation
入侵型黄蜂Vespa velutina nigrithorax比另外两种膜翅目昆虫——普通黄蜂Vespa vulgaris和蜜蜂Bombus terrestris——更容易受到昆虫病原真菌的感染。	Lacombrade, M.	PDF	N/A	Invasive Vespa velutina nigrithorax hornets are more susceptible to entomopathogenic fungus than two other hymenopteran species, the wasp Vespa vulgaris and the bumblebee Bombus terrestris.
结构泛素有助于HECT连接酶Tom1的K48连接特异性	Warner, K.	PDF	N/A	Structural ubiquitin contributes to K48 linkage-specificity of the HECT ligase Tom1
RalGAP肿瘤抑制复合物的结构与机制	Rasche, R.	PDF	N/A	Structure and mechanism of the RalGAP tumor suppressor complex
胆固醇在人类平滑受体中的感知和转运的能量学	Bansal, P. D.	PDF	N/A	Energetics of cholesterol perception and translocation in the human Smoothened receptor
E3泛素连接酶TRIP12对氧化应激反应的动态调控	Ingersoll, A. J.	PDF	N/A	Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12
接触图拓扑对RNA结构预测的影响	Faber, C.	PDF	N/A	Influence of Contact Map Topology on RNA Structure Prediction
一种多功能的反CRISPR平台，用于光遗传学和化学遗传学控制广泛同源物中的CRISPR-Cas9和Cas12	Brenker, L.	PDF	N/A	A Versatile Anti-CRISPR Platform for Opto- and Chemogenetic Control of CRISPR-Cas9 and Cas12 across a Wide Range of Orthologs
利用两阶段透明机器学习模型进行超高通量抗菌联合疗法筛选	Reuter, M. M.	PDF	N/A	Ultra-high-throughput screening of antimicrobial combination therapies using a two-stage transparent machine learning model
特异性导航决定了多隔间环境中鼠标CA1的表征结构	Pecirno, S. A.	PDF	N/A	Idiosyncratic navigation determines mouse CA1 representational structure in a multicompartment environment
CRISPRi筛选揭示了lncRNA调控人类单核细胞生长的机制	Flores-Arena, C.	PDF	N/A	CRISPRi Screen Uncovers lncRNA Regulators of Human Monocyte Growth
糖细菌部署了两种不同的IV型菌毛，推动了共生、宿主竞争和滑行运动。	Grossman, A. S.	PDF	N/A	Saccharibacteria deploy two distinct Type IV pili, driving episymbiosis, host competition, and twitching motility
分泌性白细胞蛋白酶抑制剂影响伯氏疏螺旋体感染小鼠的关节周围炎症	Yu, Q.	PDF	N/A	Secretory leukocyte protease inhibitor influences periarticular joint inflammation in B. burgdorferi-infected mice
结核分枝杆菌中一种新型放线菌特异性核糖体休眠因子	Majumdar, S.	PDF	N/A	A Novel Actinobacteria-Specific Ribosome Hibernation Factor in Mycobacterium tuberculosis
温度，而非植物品种，影响杀虫双链RNA在科罗拉多马铃薯甲虫中的效果。	Darrington, M.	PDF	N/A	Temperature, but not plant cultivar, influence the efficacy of insecticidal dsRNA in Colorado potato beetle
RNF20介导的H2B单泛素化保护停滞的复制叉并促进复制叉重启	Nagaraju, G.	PDF	N/A	RNF20-mediated H2B monoubiquitination protects stalled forks and promotes fork restart
肾皮质细胞特异性氧化代谢	Feola, K.	PDF	N/A	Cell-specific oxidative metabolism of the renal cortex
iPSC衍生的肾脏类器官和管状模型比较分析	Nunez Nescolarde, A.	PDF	N/A	Comparative analysis of iPSC-derived human kidney organoid and tubuloid models
通过针对宿主特异性引物设计实现内生真菌的有效扩增子测序，适用于纳米孔长读长测序	He, T.	PDF	N/A	Effective metabarcoding of endophytic fungi through host-exclusive primer design for nanopore long-read sequencing
太平洋牡蛎OSHV-1抗性标记存在于第8号染色体上，并不影响其对河口弧菌感染的易感性。	Surry, L. B.	PDF	N/A	The presence of the Pacific Oyster OSHV-1 resistance marker on chromosome 8 does not impact susceptibility to infection by Vibrio aestuarianus
基于Tiled PCR扩增的全基因组测序与系统发育分类加速了呼吸道合胞病毒基因组监测在加拿大的实施，作为一项试点研究	Gao, R.	PDF	N/A	Tiled PCR amplification-based Whole Genome Sequencing and Phylogenetic Classification Accelerate the Implementation of Respiratory Syncytial Virus Genomic surveillance in Canada as a Pilot Study
聚集蛋白聚糖的透明质酸结合活性对其特异性插入神经元周围网（perineuronal nets）是重要的，但并非必要条件。	Otsuka, M. Y.	PDF	N/A	The hyaluronan-binding activity of aggrecan is important, but not essential, for its specific insertion into perineuronal nets
解析真菌中III型聚酮合酶的功能多样性	Sokolova, N.	PDF	N/A	Unravelling the functional diversity of type III polyketide synthases in fungi
利用生成式人工智能设计新型CAR-T细胞疗法	Mergen, M.	PDF	N/A	Engineering de novo binder CAR-T cell therapies with generative AI
mei-P26突变体的功能缺失性分析揭示了发育过程中CO模式机制的调控	Berent, E.	PDF	N/A	Analysis of a hypomorphic mei-P26 mutation reveals developmental control of CO patterning mechanisms
# BioRxiv 2024-11-24 Papers

标题	作者	PDF链接	代码仓库	Title
一个简单的行为时间尺度突触可塑性模型，通过二进制突触和一次性学习，提供了内容可寻址记忆。	Wu, Y.	PDF	N/A	A simple model for Behavioral Time Scale Synaptic Plasticity provides content addressable memory with binary synapses and one-shot learning
基于CRISPRi的筛选在iAssembloids中进行，以阐明神经元-胶质细胞相互作用	Li, E.	PDF	N/A	CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
竹林中的迷惑互动：喜马拉雅山东部混种鸟群中的种间关联	Srinivasan, S.	PDF	N/A	Bamboozling Interactions: Interspecific associations within mixed-species bird flocks in bamboo in the Eastern Himalaya
使用ALDEx2进行RNA测序分析的显式尺度模拟	Gloor, G. B.	PDF	N/A	Explicit Scale Simulation for analysis of RNA-sequencing withALDEx2
eIF3与高翻译效率mRNA的3'-UTR末端结合	Mestre-Fos, S.	PDF	N/A	eIF3 engages with 3'-UTR termini of highly translated mRNAs
新测序的基因组揭示了特定蜻蜓（蜻蜓目：差翅亚目）基因家族扩张的模式	Tolman, E. R.	PDF	N/A	Newly Sequenced Genomes Reveal Patterns of Gene Family Expansion in select Dragonflies (Odonata: Anisoptera)
edgeR v4：功能强大的测序数据差异分析工具，扩展了功能并改进了对小计数和大数据集的支持	Chen, Y.	PDF	N/A	edgeR v4: powerful differential analysis of sequencing data with expanded functionality and improved support for small counts and larger datasets
基于实时Förster共振能量转移检测系统（FedEcs）监测的纳米载体药物释放及中风后微血栓血脑屏障穿透	Khalin, I.	PDF	N/A	Nanocarrier Drug Release and Blood-Brain Barrier Penetration at Post-Stroke Microthrombi Monitored by Real-Time F&oumlrster Resonance Energy Transfer-Based Detection System (FedEcs)
SARS-CoV-2基因组的二级结构可预测核苷酸替代频率	Hensel, Z.	PDF	N/A	Secondary structure of the SARS-CoV-2 genome is predictive of nucleotide substitution frequency
转录后模块化合成受体	Zhang, X.	PDF	N/A	Post-Transcriptional Modular Synthetic Receptors
不对称干细胞分裂维持了组织细胞的遗传异质性。	Bener, M. B.	PDF	N/A	Asymmetric stem cell division maintains genetic heterogeneity of tissue cells
互补的脊椎动物Wac模型表现出与DeSanto-Shinawi综合征相关的表型	Lee, K.-H.	PDF	N/A	Complimentary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome
低覆盖度测序的法医学似然比	Ouerghi, F.	PDF	N/A	On forensic likelihood ratios from low-coverage sequencing
脂质组学和代谢组学插补（ImpLiMet）：用于缺失数据插补优化和方法选择的在线应用	Ou, H.	PDF	N/A	Imputation for Lipidomics and Metabolomics (ImpLiMet): Online application for optimization and method selection for missing data imputation
MLL4调控出生后腭部生长和中腭缝发育	Lee, J.-M.	PDF	N/A	MLL4 regulates postnatal palate growth and midpalatal suture development
西尼罗病毒感染期间尖音库蚊中肠的单细胞图谱	Fitzmeyer, E. A.	PDF	N/A	A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection
调节前额叶皮层活动以缓解压力引起的工作记忆缺陷：一项经颅直流电刺激（tDCS）研究	Roy, S.	PDF	N/A	Modulating Prefrontal Cortex Activity to Alleviate Stress-Induced Working Memory Deficits: A Transcranial Direct Current (tDCS) Study
植物细胞壁的纤维网络性质能够为发育提供可调的力学性能	Chen, S.	PDF	N/A	Fibrous Network Nature of Plant Cell Walls Enables Tunable Mechanics for Development
生物医学数据的AI准备性：Bridge2AI建议	Clark, T.	PDF	N/A	AI-readiness for Biomedical Data: Bridge2AI Recommendations
使用CryFold改进冷冻电镜图的自动化模型构建	Su, B.	PDF	N/A	Improved automated model building for cryo-EM maps using CryFold
层粘连蛋白β4对于人类外周感觉神经元的发育是必需的。	Saito-Diaz, K.	PDF	N/A	Laminin β4 is required for the development of human peripheral sensory neurons
从单细胞数据中映射增强子-基因调控相互作用	Sheth, M. U.	PDF	N/A	Mapping enhancer-gene regulatory interactions from single-cell data
大肠杆菌细胞宽度稳态和膨胀动力学的力学机制：MreB和隔膜抑制的影响	Kale, T.	PDF	N/A	Mechanics of E. coli cell width homeostasis and bulging dynamics from MreB and septum inhibition
使用常微分方程测量分裂酵母细胞中的调控网络继承	Wu, W.	PDF	N/A	Measuring regulatory network inheritance in dividing yeast cells using ordinary differential equations
荧光蛋白标记的阴暗面：蛋白质标签对生物分子凝聚的影响	Fatti, E.	PDF	N/A	The dark side of fluorescent protein tagging: the impact ofprotein tags on biomolecular condensation
肌醇需求酶1途径和自噬驱动内皮细胞对发热范围高热的顺序应答	Vorbe, J.	PDF	N/A	Inositol-Requiring Enzyme 1 Pathway and Autophagy Drive Sequential Response of Endothelial Cells to Febrile Range Hyperthermia
耐寒蟋蟀在脂肪体组织中强化其肌动蛋白细胞骨架	van Oirschot, M. L.	PDF	N/A	Freeze-tolerant crickets fortify their actin cytoskeleton in fat body tissue
缩小规模以提高效率：用于蛋白质序列迁移学习的中型Transformer模型	Vieira, L. C.	PDF	N/A	Scaling Down for Efficiency: Medium-Sized Transformer Models for Protein Sequence Transfer Learning
利用优化的SIBR-Cas系统在Cupriavidus necator H16中实现简化和高效的基因组编辑	Della Valle, S.	PDF	N/A	Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
通过广泛调查外壳成分，推进细菌孢子上的蛋白质展示	Chappell, T. C.	PDF	N/A	Advancing protein display on bacterial spores through an extensive survey of coat components
全球神经元形状推理与点亲和变压器	Troidl, J.	PDF	N/A	Global Neuron Shape Reasoning with Point Affinity Transformers
视觉言语通过不同的机制增强听觉起始时间和包络追踪	Cao, C. Z.	PDF	N/A	Visual speech enhances auditory onset timing and envelope tracking through distinct mechanisms
在脑刺激反应波动中分离三种变异性和噪声来源	Ma, K.	PDF	N/A	Separating three variability and noise sources in the response fluctuation of brain stimulation
热应激通过促进弧菌科（Vibrionaceae）的生长，影响了大西洋鲑鱼的肠道微生物群，并伴随着大量黏液的产生。	Bowman, J. P.	PDF	N/A	Heat stress impacts the gut microbiome of Atlantic salmon by promoting growth of Vibrionaceae and is associated with extensive cast production
具有两种不同DNA结合模式的保守ComP结构——使用AlphaFold3、RoseTTAFold2NA、Chai-1进行系统建模及在HADDOCK中重新对接	Helsem, S.	PDF	N/A	The conserved ComP structure with two distinct DNA binding modes - systematic modeling with AlphaFold3, RoseTTAFold2NA, Chai-1 and re-docking in HADDOCK
普雷沃氏菌属copri与代谢功能障碍相关脂肪性肝病进展中的肝纤维化进展之间的关联	Leitman, M.	PDF	N/A	The Association Between Prevotella copri and Advanced Fibrosis in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease
细菌性枯萎病对高良姜可培养内生真菌群落组成和多样性的影响	Wang, L.	PDF	N/A	Effects of Bacterial Wilt on Community Composition and Diversity of Culturable Endophytic Fungi in Alpinia galanga
双BONCAT揭示了盐沼沉积物中昼夜活跃的微生物群落的差异	Maierhaba, Y.	PDF	N/A	Dual-BONCAT Reveals Distinct Day- and Night-Active Microbial Populations in Salt Marsh Sediments
多样的噬菌体防御系统定义了西非南美大流行霍乱弧菌	Adams, D. W.	PDF	N/A	Diverse phage defence systems define West African South American pandemic Vibrio cholerae
亚马孙部落亚诺马米人的皮肤微生物群复杂性挑战了当前对健康皮肤的普遍概念。	Durack, J.	PDF	N/A	Yanomami skin microbiome complexity challenges prevailing concepts of healthy skin.
一种由多种菌株组成、能够形成生物膜的枯草芽孢杆菌（Bacillus spp.）和片球菌属（Pediococcus spp.）混合物改变了聚乙烯犊牛舍表面的微生物组成。	Reynolds, C. A.	PDF	N/A	A Multi-Strain, Biofilm-Forming Cocktail of Bacillus spp. and Pediococcus spp. Alters the Microbial Composition on Polyethylene Calf Housing Surfaces
接受抗CD49d和肌营养不良蛋白外显子跳跃吗啉代处理的mdx小鼠；力损失减少及基因表达通路改变支持ATL1102联合疗法在DMD患者中的应用。	Padhye, A. S.	PDF	N/A	Mdx mice dosed with antisense to CD49d and dystrophin exon skip morpholino; reduced force loss and affected gene expression pathways support ATL1102 combination therapy in DMD patients
登革病毒蛋白酶介导的巨噬细胞激活与极化	Misra, R.	PDF	N/A	Dengue Protease-Mediated Activation and Polarization of Macrophages
漆黄素在隐性营养不良性大疱性表皮松解症的小鼠模型中延长了寿命。	Miller, W. C.	PDF	N/A	Fisetin extends lifespan in a murine model of recessive dystrophic epidermolysis bullosa
在出芽酵母中，UPR（未折叠蛋白反应）的缺陷揭示了内质网折叠能力与维持整倍体之间的权衡。	Bartolutti, C.	PDF	N/A	UPR deficiency in budding yeast reveals a trade-off between ER folding capacity and maintenance of euploidy
功能性分裂tRNA：密码子解码机制的新视角	Mureev, S.	PDF	N/A	Functional split-tRNA: a new perspective on codon decoding mechanism
一种偏好腺苷碱基编辑器，具有最小的旁观者效应和脱靶编辑	Shang, M.	PDF	N/A	A motif preferred adenine base editor with minimal bystander and off-targets editing
寄生虫、宿主、猎物和环境之间的LINE-RTE逆转录转座子的水平转移。	Brann, T.	PDF	N/A	Horizontal transfer of a LINE-RTE retrotransposon among parasite, host, prey and environment.
使用计数分割评估合成重复样本中的RNA速度稳定性	Li, Y.	PDF	N/A	Assessing RNA velocity stability across syntheticreplicates using count splitting
哺乳动物进化过程中RNA修饰的保守景观与转录多样性	Rodriguez, G. S.	PDF	N/A	The conserved landscape of RNA modifications and transcript diversity across mammalian evolution
非人灵长类动物在情境依赖性物体序列中的灵活学习和重新排序	Wen, X.	PDF	N/A	Flexible Learning and Re-ordering of Context-dependent Object Sequences in Nonhuman Primates
3-硝氧基丙醇对荷斯坦牛和瑞士褐牛肠道甲烷排放的不同影响，及其与金合欢单宁提取物缺乏协同作用	Islam, M. Z.	PDF	N/A	Divergent effects of 3-nitrooxypropanol on enteric methane emissions in Holstein and Brown Swiss cows, and its lack of synergy with Acacia mearnsii tannin extract
TDP-43及其C端片段在体外增强的聚集，而非相分离，产生了深蓝色的自体荧光。	Saravanan, P.	PDF	N/A	Enhanced in vitro aggregation, but not phase separation, of TDP-43 and its C-terminal fragments generate deep-blue autofluorescence.
金属感应传感器组氨酸激酶ZraS细胞质域构象动力学的洞察	Mahapatra, N.	PDF	N/A	Insights into the conformational dynamics of the cytoplasmic domain of metal-sensing sensor histidine kinase ZraS
采血部位和血样基质影响矿物质评估	Alejandro, M. G.	PDF	N/A	Blood draw site and blood matrix influence mineral assessment
使用BERT分词器建模引物-模板相互作用以通过注意力-BiLSTM预测PCR扩增	Latifian, N.	PDF	N/A	Modeling Primer-Template Interactions using BERT Tokenizer to Predict PCR Amplification with Attention-BiLSTM
MAT2a和AHCY抑制破坏抗氧化代谢并减少胶质母细胞瘤细胞存活	Rowland, E. C.	PDF	N/A	MAT2a and AHCY Inhibition Disrupts Antioxidant Metabolism and Reduces Glioblastoma Cell Survival
单CAR-双靶点：抗PD-L1 CAR T细胞的颅内递送有效根除胶质瘤及肿瘤微环境中的免疫抑制细胞。	Ulloa-Navas, M. J.	PDF	N/A	Single CAR-Dual target: Intracranial Delivery of Anti-PD-L1 CAR T Cells Effectively Eradicates Glioma and Immunosuppressive Cells in the Tumor Microenvironment.
mTOR抑制减轻了tau蛋白磷酸化引起的线粒体功能障碍、氧化应激和认知功能障碍。	Tang, Z.	PDF	N/A	mTOR inhibition alleviated tau phosphorylation-induced mitochondrial impairment, oxidative stress, and cognitive impairment
单神经元激活赋予了认知任务中涌现电路解决方案的归纳偏置	Tolmachev, P.	PDF	N/A	Single-unit activations confer inductive biases for emergent circuit solutions to cognitive tasks
青少年三重网络动态及其未来饮酒行为	McIntyre, C. C.	PDF	N/A	Triple network dynamics and future alcohol consumption in adolescents
阿尔茨海默病风险基因MS4A4A和MS4A6A协同作用，负向调控TREM2及小胶质细胞状态	Rosner, D.	PDF	N/A	The Alzheimers Disease Risk Genes MS4A4A And MS4A6A Cooperate to Negatively Regulate Trem2 and Microglia states
控制二元和加权网络中的互惠性：一种新颖的密度保持方法	Hadaeghi, F.	PDF	N/A	Controlling Reciprocity in Binary and Weighted Networks: A Novel Density-Conserving Approach
一项关于早期生活压力对前额叶皮层转录组影响的元分析表明，其具有长期影响髓鞘的作用。	Duan, T. Q.	PDF	N/A	A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin
脑特征图揭示了在腹侧流中逐步形成的动物特征表征。	Zhang, Z.	PDF	N/A	Brain Feature Maps Reveal Progressive Animal-Feature Representations in the Ventral Stream.
沙门氏菌对胆汁压力的抵抗力因抗氧化酶YqhD介导的排出泵活性降低而受损。	Parmar, K.	PDF	N/A	The resilience of Salmonella to bile stress is impaired due to the reduced efflux pump activity mediated by the antioxidant enzyme YqhD
抗生素治疗和微生物群耗竭减缓刺胞动物再生	Da-Anoy, J.	PDF	N/A	Antibiotic treatment and microbiome depletion slow cnidarian regeneration
大西洋鲑鱼养殖于温暖水域的胃肠道黏膜层细菌的特性研究	Hall, K.	PDF	N/A	Characterization of bacteria colonizing the mucosal layer of the gastrointestinal tract of Atlantic salmon farmed in a warm water region
X-信号元件sex-1在胚胎性别决定和剂量补偿中的多层次转录调控	Jash, E.	PDF	N/A	Multi-level transcriptional regulation of embryonic sex determination and dosage compensation by the X-signal element sex-1
# BioRxiv 2024-11-23 Papers

标题	作者	PDF链接	代码仓库	Title
NAVIP：揭示邻近小序列变异对功能影响预测的影响	Baasner, J.-S.	PDF	N/A	NAVIP: Unraveling the Influence of Neighboring Small Sequence Variants on Functional Impact Prediction
评估临床前心血管研究中的研究设计严谨性：一项重复性研究	Zahiri, K.	PDF	N/A	Evaluating Study Design Rigor in Preclinical Cardiovascular Research: A Replication Study
多发性骨髓瘤相关DIS3突变驱动AID依赖性IgH易位	Kulinski, T. M.	PDF	N/A	Multiple Myeloma associated DIS3 mutations drive AID-dependent IgH Translocations
RNAmigos2：基于结构的RNA虚拟筛选，结合半监督图学习和大规模对接数据，实现快速且准确的结果	Carvajal-Patino, J. G.	PDF	N/A	RNAmigos2: Fast and accurate structure-based RNA virtual screening with semi-supervised graph learning and large-scale docking data
铜绿假单胞菌极性鞭毛组装的时空和数量调控	Pulido-Sanchez, M.	PDF	N/A	Spatial, temporal and numerical regulation of polar flagella assembly in Pseudomonas putida
通过分子模拟探索Abeta42单体在纤维表面上的扩散动力学	Ma, Y.-W.	PDF	N/A	Exploring Abeta42 Monomer Diffusion Dynamics on Fibril Surfaces through Molecular Simulations
在决策过程中，无论是提升还是降低决策质量，噪音的来源	Shen, B.	PDF	N/A	Origins of noise in both improving and degrading decision making
威胁处理过程中的大脑动态与时空轨迹	Misra, J.	PDF	N/A	Brain dynamics and spatiotemporal trajectories during threat processing
各向异性水凝胶降解增强三维集体细胞排列、力传导和成骨分化	Garrido, C. A.	PDF	N/A	Anisotropic Hydrogel Degradation Enhances 3D Collective Cell Alignment, Mechanotransduction and Osteogenic Differentiation
通过多模态堆叠提高认知能力的全脑关联的可预测性、重测信度和普适性	Tetereva, A.	PDF	N/A	Improving Predictability, Test-Retest Reliability and Generalisability of Brain-Wide Associations for Cognitive Abilities via Multimodal Stacking
ErbB2/HER2通过调节c-Myc和cyclin D的功能，调控CDK4抑制剂的敏感性、G1/S期转换的时机和不可逆性。	Ichikawa, A. N.	PDF	N/A	ErbB2/HER2 governs CDK4 inhibitor sensitivity and timing and irreversibility of G1/S transition by altering c-Myc and cyclin D function
基于全脑成像的细胞c-Fos表达的迷幻药和精神活性药物分类	Aboharb, F.	PDF	N/A	Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression
一种开花时间可塑性的反应规范揭示了玉米适应的生理足迹	Drouault, J.	PDF	N/A	A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation
鼻内给予丹曲林纳米颗粒抑制脂多糖诱导的小鼠抑郁和焦虑行为	Liu, J.	PDF	N/A	Intranasal dantrolene nanoparticles inhibit lipopolysaccharide-induced depression and anxiety behavior in mice
结合转录组学、连接性和活性分析，利用高度放大的多重原位杂交技术（hamFISH）对内侧杏仁核进行研究	Edwards, M. D.	PDF	N/A	Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH)
基于聚丙烯酰胺的抗菌共聚物：替代或拯救抗生素	Williams, S. C.	PDF	N/A	Polyacrylamide-based Antimicrobial Copolymers to Replace or Rescue Antibiotics
室温下绿色荧光蛋白的气溶胶脱水	Pan, Z.	PDF	N/A	Room-Temperature Aerosol Dehydration of Green Fluorescent Protein
LIET模型：从加载到终止，捕捉RNA聚合酶的动力学过程	Stanley, J. T.	PDF	N/A	LIET Model: Capturing the kinetics of RNA polymerase from loading to termination
利用鸡胚绒毛尿囊膜模型评估肿瘤定植沙门氏菌株	Mon, K. K. Z.	PDF	N/A	Evaluation of Tumor-colonizing Salmonella Strains using the Chick Chorioallantoic Membrane Model
单剂量禽流感A(H5N1)谱系2.3.4.4b血凝素-基质-M纳米颗粒疫苗在非人灵长类动物中诱导了中和反应	Patel, N.	PDF	N/A	Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M nanoparticle vaccine induces neutralizing responses in nonhuman primates
PyEvoCell：一个增强型大型语言模型单细胞轨迹分析仪表板	Mathur, S.	PDF	N/A	PyEvoCell: An LLM- Augmented Single Cell Trajectory Analysis Dashboard
研究光系统II中TyrD、TyrZ和QA*-形成引起的Soret区域电致变色带移	Boussac, A.	PDF	N/A	Investigation of electrochromic band-shifts in the Soret region induced by the formation of TyrD, TyrZ, and QA*- in Photosystem II
一种参考基因组：Trichogramma kaykai，一种生活在沙漠中的小型寄生蜂，具有竞争性的性比破坏者	Culotta, J.	PDF	N/A	A reference genome for Trichogramma kaykai: A tiny desert-dwelling parasitoid wasp with competing sex-ratio distorters
使用TubeTracker进行半自动高内涵花粉性能分析	Yimga Ouonkap, S. V.	PDF	N/A	Semi-automated High Content Analysis of Pollen Performance Using TubeTracker
人脑中的大规模信号传播模式	Song, Y.	PDF	N/A	Large-scale Signal Propagation Modes in the Human Brain
药物抑制SUMOylation在小鼠附睾白色脂肪组织中再现了遗传性低SUMOylation	Dufour, D.	PDF	N/A	Pharmacological inhibition of SUMOylation recapitulates genetic hypoSUMOylation in the murine epididymal white adipose tissue
六足束缚：一种新描述的昆虫步态	Amir, A.	PDF	N/A	Six-legged-bound: a newly-described insect gait
硬骨鱼类不同的视觉运动策略：斑马鱼和小头鱼脑中的神经回路机制	Fouke, K. E.	PDF	N/A	Divergent Visuomotor Strategies in Teleosts: Neural Circuit Mechanisms in Zebrafish and Danionella cerebrum
皮质生物混合植入物的光遗传学刺激指导目标导向行为	Brown, J.	PDF	N/A	Optogenetic stimulation of a cortical biohybrid implant guides goal directed behavior
任务诱发的内部身体状态而非大脑状态调节人类自我感知	Xie, M.	PDF	N/A	Task-induced internal bodily rather than brain states regulate human self-perception
神经支配密度调控基于GPCR的去甲肾上腺素和多巴胺传感器的交叉干扰	Lopez, R. C.	PDF	N/A	Innervation density governs crosstalk of GPCR-based norepinephrine and dopamine sensors
对家族性阿尔茨海默病生物标志物研究中的五种淀粉样β肽进行无偏差的数据驱动分析	Llorente-Saguer, I.	PDF	N/A	Unbiased data-driven analysis of five amyloid-beta peptides for biomarker investigations in familial Alzheimer's disease
神经肽受体转录调控解析肽能调节行为与生理的复杂性。	Ryu, S.	PDF	N/A	Transcriptional Regulation of Neuropeptide Receptors Decodes Complexity of Peptidergic Modulation of Behavior and Physiology.
SARS-CoV-2在源自人类诱导多能干细胞（hiPSC）的神经元中的感染依赖于组织蛋白酶，并导致HIF1α和磷酸化tau的积累。	Kettunen, P.	PDF	N/A	SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes accumulation of HIF1alpha and phosphorylated tau
直接从临床拭子中测序沙眼衣原体和其他细菌性性传播感染基因组的挑战：最佳解决方案	Buttner, K. A.	PDF	N/A	The challenge of sequencing Chlamydia trachomatis and other bacterial STI genomes directly from clinical swabs: the optimum solution
环境灾难期间多倍体现象的兴起	Chen, H.	PDF	N/A	The Rise of Polyploids During Environmental Catastrophes
UniversalEPI：利用注意力机制解码稀有和未探索细胞类型中的染色质相互作用	Grover, A.	PDF	N/A	UniversalEPI: Harnessing Attention Mechanisms to Decode Chromatin Interactions in Rare and Unexplored Cell Types
重新编程M13噬菌体基因组，用于一体化个性化癌症疫苗	Huang, S.	PDF	N/A	Reprogramming the genome of M13 bacteriophage for all-in-one personalized cancer vaccine
用于从单细胞RNA测序数据中进行无监督细胞聚类的新算法	Robles, M.	PDF	N/A	New algorithms for unsupervised cell clusteringfrom scRNA-seq data
通过组合式池化实现稳健且成本效益高的单细胞测序	Gawron, J.	PDF	N/A	Robust and cost-efficient single-cell sequencing through combinatorial pooling
CNV-Finder：简化拷贝数变异发现流程	Kuznetsov, N.	PDF	N/A	CNV-Finder: Streamlining Copy Number Variation Discovery
在组织病理学中使用统一扩散框架进行多功能的污渍转移	Yan, X.	PDF	N/A	Versatile Stain Transfer in Histopathology Using a Unified Diffusion Framework
由突变NEK1聚集驱动的肌萎缩侧索硬化症（ALS）在Pml丢失的情况下会加速发展，但通过药物诱导Pml介导的降解可以临床上逆转这一过程。	Georgiadou, P.	PDF	N/A	ALS driven by mutant NEK1 aggregation is accelerated by Pml loss, but clinically reversed through pharmacologic induction of Pml-mediated degradation
克罗恩病中持续炎症上皮祖细胞状态的表观遗传基础	Karakasheva, T. A.	PDF	N/A	An epigenetic basis for sustained inflammatory epithelial progenitor cell states in Crohn's disease
通过高效招募mRNA到合成细胞膜上实现膜蛋白的原位表达	Fu, H.	PDF	N/A	In situ Membrane Protein Expression by Efficient Recruitment of mRNA to the Membranes of Synthetic Cells
在系统性幼年特发性关节炎中发生的药物相关性肺泡蛋白沉积症期间，表达IFNγ的髓系细胞定位于脂蛋白沉积物中。	Delmastro, A.	PDF	N/A	IFNγ-Expressing Myeloid Cells Localize within Lipoproteinosis during Drug-Associated Pulmonary Alveolar Proteinosis occurring in Systemic Juvenile Idiopathic Arthritis
热休克因子2通过重塑染色质景观正向调控致癌性疱疹病毒基因表达	Cutrone, L.	PDF	N/A	Heat shock factor 2 positively regulates oncogenic herpesvirus gene expression by remodeling the chromatin landscape
感染疫霉菌的诺维病毒能够减弱其营养生长，促进孢子囊形成，并赋予宿主卵菌超强毒力。	Sakuta, K.	PDF	N/A	Novel endornaviruses infecting Phytophthora cactorum that attenuate vegetative growth, promote sporangia formation, and confer hypervirulence to the host oomycete.
来自直肠样本的沙眼衣原体基因组：描述包含阿根廷ompA基因型L4的新分支	Buttner, K. A.	PDF	N/A	Chlamydia trachomatis genomes from rectal samples: description of new clade comprising ompA-genotype L4 from Argentina
通过多搜索引擎和重新评分最大化基于免疫肽组学的细菌表位发现	Willems, P.	PDF	N/A	Maximizing immunopeptidomics-based bacterial epitope discovery by multiple search engines and rescoring
从泰国斑鸠粪便中分离出的酵母Hyphopichia burtonii的全基因组测序	Ngasaman, R.	PDF	N/A	Whole-genome sequencing of Hyphopichia burtonii from isolated yeast recovered from zebra dove droppings in Thailand
成对相互作用和连续瓶颈效应有助于解释多物种微生物群落的物种组成	Lele, K.	PDF	N/A	Pairwise interactions and serial bottlenecks help explain species composition in a multi-species microbial community
介绍SPROUT（使用阈值处理的半自动化区域分割输出）：一种可适应的计算机视觉工具，用于生成3D分割	He, Y.	PDF	N/A	Introducing SPROUT (Semi-automated Parcellation of Region Outputs Using Thresholding): an adaptable computer vision tool to generate 3D segmentations
精氨酰转移酶1驱动一个依赖线粒体的程序以诱导细胞死亡	Kumar, A.	PDF	N/A	Arginyltransferase1 drives a mitochondria-dependent program to induce cell death
如何预测有效的药物组合 - 超越协同评分	Eckhart, L.	PDF	N/A	How to Predict Effective Drug Combinations - Moving beyond Synergy Scores
VIACOT：一个用于交互式可视化和比较细胞谱系树的网络服务器	Yang, J.	PDF	N/A	VIACOT: a web server for interactive visualization and comparison of cell lineage trees
利用人类泛基因组资源描述人类可变转座子插入的胞嘧啶甲基化	Zhuo, X.	PDF	N/A	Characterizing cytosine methylation of polymorphic human transposable element insertions using human pangenome resources
TMVisDB：一种用于跨膜蛋白注释和三维可视化的资源	Olenyi, T.	PDF	N/A	TMVisDB: A Resource for Transmembrane Protein Annotations and 3D Visualizations
通过局部活动和全局敏感化实现受体极化	Goetz, A.	PDF	N/A	Receptor polarization through localized activity and global sensitization
机械应力调控肌细胞融合与肌管生长	Le Toquin, Y.	PDF	N/A	Mechanical stresses govern myoblast fusion and myotube growth
本地高蛋白、植物基即用型治疗食品增强了大鼠的消瘦恢复能力	Bechoff, A.	PDF	N/A	Local High-Protein, Plant-Based Ready-to-Use Therapeutic Food Enhances Recovery from Malnutrition in Rats
Shroom3-Rock相互作用及促纤维化功能：解析内含子CKD风险等位基因的机制。	Reghuvaran, A. C.	PDF	N/A	Shroom3-Rock interaction and profibrotic function: Resolving mechanism of an intronic CKD risk allele.
哥斯达黎加野生树懒的胃肠道寄生虫宿主特异性	Vanderheoven, E.	PDF	N/A	Host specificity of gastrointestinal parasites in free-ranging sloths from Costa Rica
社会隔离降低了野生型斑马鱼（Danio rerio）的代谢率和社交偏好	Ghosh, A.	PDF	N/A	Social isolation reduces metabolic rate and social preference in Wild-type Zebrafish (Danio rerio)
基于结构的共价纳米抗体结合剂设计用于热稳定绿色荧光蛋白	Yue, Z.	PDF	N/A	Structure-Based Design of Covalent Nanobody Binders for a Thermostable Green Fluorescence Protein
# BioRxiv 2024-11-22 Papers

标题	作者	PDF链接	代码仓库	Title
脑岛和颞上沟在社会决策中对人际内疚和责任感的贡献	Gaedeke, M.	PDF	N/A	Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions
在向极地范围扩展过程中，生态和进化的快速分化	Sheffer, M. M.	PDF	N/A	Rapid ecological and evolutionary divergence during a poleward range expansion
GraphComm：一种基于图的深度学习方法，用于预测单细胞RNAseq数据中的细胞间通讯	So, E.	PDF	N/A	GraphComm: A Graph-based Deep Learning Method to Predict Cell-Cell Communication in single-cell RNAseq data
设计可靠且准确的表观遗传时钟：选择最佳的计算解决方案	Vavourakis, C. D.	PDF	N/A	Devising reliable and accurate epigenetic clocks: choosing the optimal computational solution
跨越解剖长度尺度和物种的3D白质通路几何组织桥梁	Kjer, M.	PDF	N/A	Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species
Galectin-9通过调节RhoA活性来调控树突状细胞的极性和尾足收缩。	Franken, G.	PDF	N/A	Galectin-9 regulates dendritic cell polarity and uropod contraction by modulating RhoA activity
WhatIsMyGene：回归基因富集的基本原理	Hodge, K. G.	PDF	N/A	WhatIsMyGene: Back to the Basics of Gene Enrichment
WhatIsMyGene：回归基因富集的基本原理	Hodge, K. G.	PDF	N/A	WhatIsMyGene: Back to the Basics of Gene Enrichment
血红素的相关性真实吗？重新审视包括HRG-9和HRG-10在内的TANGO2同源基因在秀丽隐杆线虫中的作用	Sandkuhler, S. E.	PDF	N/A	Heme's relevance genuine? Re-visiting the roles of TANGO2 homologs including HRG-9 and HRG-10 in C. elegans
使用概率主题建模估计全基因组系统发育树	Khodaei, M.	PDF	N/A	Estimating Genome-wide Phylogenies Using Probabilistic Topic Modeling
用微藻替代饲料中的鱼油对金头鲷中肠细菌微生物群的影响	Katsoulis-Dimitriou, S.	PDF	N/A	The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota
通过致癌假激酶PEAK1对CAMK2的前馈刺激，在三阴性乳腺癌中生成了一种具有治疗潜力的信号轴。	Yang, X.	PDF	N/A	Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer
CMTM6通过维持B细胞内在的CD40表达，以调节抗肿瘤免疫。	Long, Y.	PDF	N/A	CMTM6 maintains B cell intrinsic CD40 expression to regulate anti-tumor immunity
使用深度强化学习进行果蝇真实运动的全身体模拟	Vaxenburg, R.	PDF	N/A	Whole-body simulation of realistic fruit fly locomotion with deep reinforcement learning
进化上较新的人类基因的功能关联对三维基因组景观和疾病具有敏感性。	Fleck, K.	PDF	N/A	Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease
研究睡眠期间大脑活动的时序动态及其成熟过程：早产儿与足月婴儿的脑电微状态研究。	Adibpour, P.	PDF	N/A	Characterizing the temporal dynamics and maturation of brain activity during sleep: an EEG microstate study in preterm and full-term infants.
肝毒性和胆汁淤积性肝纤维化模型中隔室特异性蛋白质组景观的动态变化	Jirouskova, M.	PDF	N/A	Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis
一种用于阿根廷蚂蚁食物偏好实验的高通量且灵敏的方法	Wagner, T.	PDF	N/A	A high-throughput and sensitive method for food preference assays in the Argentine ant
异种线粒体移植可减轻心脏骤停后的心肌功能障碍	Wang, Z.	PDF	N/A	Transplantation of exogenous mitochondria mitigates myocardial dysfunction after cardiac arrest
基因灭活β1肾上腺素受体可防止斑马鱼脑部海绵状血管畸形	Li, W.	PDF	N/A	Genetic Inactivation of the beta1 adrenergic receptor prevents Cerebral Cavernous Malformations in zebrafish
自由移动的狨猴使用头戴式眼动追踪进行主动视觉	Singh, V. P.	PDF	N/A	Active vision in freely moving marmosets using head-mounted eye tracking
早期视觉皮层和面部选择性脑区中空间选择性的常见模式	Morsi, A. Y.	PDF	N/A	Common patterns of spatial selectivity in early visual cortex and face-selective brain regions
早期肠道炎症驱动了微生物组-内分泌-大脑轴的性别依赖性转变	Sullivan, O.	PDF	N/A	Early-Life Gut Inflammation Drives Sex-Dependent Shifts in the Microbiome-Endocrine-Brain Axis
通过通信理论研究时间分辨的功能连接：相位同步与滑动窗口皮尔逊相关之间的互补性。	Wiafe, S.-L.	PDF	N/A	Studying time-resolved functional connectivity via communication theory: on the complementary nature of phase synchronization and sliding window Pearson correlation.
成人颞叶新皮质第1层中兴奋性突触小体的超微结构亚层特异性多样性	Rollenhagen, A.	PDF	N/A	Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex
在时间决策中发起追求的价值	Sutlief, E.	PDF	N/A	The value of initiating a pursuit in temporal decision-making
CD28通过调节ZAP70激活和Lck动力学来塑造T细胞受体信号传导	Raychaudhuri, K.	PDF	N/A	CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics
通过单轮成像实现三维组织中的彩色条码超多重RNA荧光原位杂交	Chang, T.	PDF	N/A	Color-barcoded Super-multiplex RNA FISH in Three-dimensional Tissues through Single-round Imaging
新型长链非编码RNA——CyKILR的RNA剪接变体在非小细胞肺癌中具有不同的生物学功能	Xie, X.	PDF	N/A	RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer
KLF6在肺动脉高压中的双重角色：既是朋友也是敌人	Alharbi, R.	PDF	N/A	KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe
地中海地区开放植被火灾中气候变化物种的排放——方法和数据的综述	Hundal, R. A.	PDF	N/A	Emissions of climate-altering species from open vegetation fires in the Mediterranean region - A review on methods and data
细胞类型特异的表观遗传时钟，用于在细胞类型分辨率上量化生物年龄	Tong, H.	PDF	N/A	Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution
IFITM3的CD225结构域通过模拟SNARE实现对同型晚期内体融合的调控	Rahman, K.	PDF	N/A	SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusion
一种用于精确递送蛋白质、核酸和治疗药物的模块化封装系统	Luong, T. D.	PDF	N/A	A modular encapsulation system for precision delivery of proteins, nucleic acids and therapeutics
一种灵活的高精度光声视网膜假体	Leong, A.	PDF	N/A	A flexible high-precision photoacoustic retinal prosthesis
光系统II释放氧气后，能够进展到S1状态的S0状态的重组动力学	Boussac, A.	PDF	N/A	Kinetics of reformation of an S0 state capable of progressing to an S1 state after the O2 release by Photosystem II
磷酸化诱导的SUMO化促进了Ulk4在纤毛尖端的凝聚，以传导Hedgehog信号	Zhou, M.	PDF	N/A	Phosphorylation-induced SUMOylation promotes Ulk4 condensation at ciliary tip to transduce Hedgehog signal
从诱导多能干细胞发展调控内皮向造血转变	Wellington, R.	PDF	N/A	Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells
对Synechocystis 6803和Thermosynechococcus vestitus中光系统II功能中残基D1/V185作用的新见解。	Boussac, A.	PDF	N/A	New insights into the involvement of residue D1/V185 in Photosystem II function in Synechocystis 6803 and Thermosynechococcus vestitus.
细胞周期蛋白A和细胞周期蛋白B的mRNA转录后调控由Bruno 1和Cup介导，并在P-bodies内进一步微调。	Bayer, L. V.	PDF	N/A	Post-transcriptional regulation of cyclin A and cyclin B mRNAs is mediated by Bruno 1 and Cup, and further fine-tuned within P-bodies
基于代理的拟南芥合子中皮层微管带运动模拟	Nonoyama, T.	PDF	N/A	Agent-Based Simulation of Cortical Microtubule Band Movement in the Arabidopsis Zygote
先验的相关性如何？贝叶斯因果推断在易变环境中的动态感知	Meijer, D.	PDF	N/A	How relevant is the prior? Bayesian causal inference for dynamic perception in volatile environments
Ccp1的耗竭破坏了海马区小清蛋白中间神经元的网络整合	Le Bail, R.	PDF	N/A	Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons
CelLink：整合单细胞多组学数据，处理弱特征关联与细胞群体不平衡问题	Luo, X.	PDF	N/A	CelLink: integrating single-cell multi-omics data with weak feature linkage and imbalanced cell populations
工作记忆中感觉和运动内容的动态优先级排序	Echeverria-Altuna, I.	PDF	N/A	Dynamic prioritisation of sensory and motor contents in working memory
单个神经元对特定模态和非模态语言的处理	Lakretz, Y.	PDF	N/A	Modality-Specific and Amodal Language Processing by Single Neurons
靶向激活小胶质细胞PPARδ可重编程免疫代谢，并增强饮食诱导肥胖中的胰岛素敏感性。	Jiao, H.	PDF	N/A	Targeted activation of microglial PPARdelta reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity.
面向多模态纵向分析以预测认知衰退	Ashish, R. M.	PDF	N/A	Towards Multimodal Longitudinal Analysis for Predicting Cognitive Decline
伊维菌素残留对粪生昆虫的背景依赖性影响：与环境压力源、体型和性别在一种腐蝇（Sepsis neocynipsea）中的相互作用	Walker, J.	PDF	N/A	Context-dependent effects of ivermectin residues on dung insects: Interactions with environmental stressors, size, and sex in a sepsid fly (Sepsis neocynipsea)
昆虫肠道中的免疫启动：通过超微结构和转录组变化揭示的动态反应	Baur, M.	PDF	N/A	Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes
破伤风类毒素通过靶向肿瘤唾液酸和增强细胞毒性CD4+ T细胞对胰腺癌的反应，利用双面抗癌机制	Giurini, E.	PDF	N/A	Tetanus Toxoid Utilizes Dual-Faceted Anticancer Mechanism Through Targeting Tumoral Sialic Acids and Enhancing Cytotoxic CD4+ T cell Responses Against Pancreatic Cancer
淀粉体对于地钱（Marchantia polymorpha）叶状体的完全向地性是必要的。	Hashimoto-Sugimoto, M.	PDF	N/A	Amyloplasts are necessary for full gravitropism in thallus of Marchantia polymorpha
古埃及前王朝时期考古遗存中高δ15N值：极端条件下局部土壤施肥实践的潜在指标	Poulallion, E.	PDF	N/A	High δ15N values in Predynastic Egyptian archeological remains: A potential indicator for localised soil fertilisation practices in extreme conditions
以环丙沙星作为唯一碳源和能量来源，并展现出向可培养纳米级细菌的显著转变，由医院废水分离的克雷伯氏菌属SG01株所展示。	Chakraborty, R.	PDF	N/A	Consumption of Ciprofloxacin as the sole Carbon and energy source and Phenomenal Transformation to a Culturable nanometer-sized- bacterium demonstrated by a hospital-waste-water isolate Klebsiella&nbsp sp. SG01
硝酸铅对人类角质形成细胞（HaCaT）的毒性作用。	Mohamed, A.	PDF	N/A	The toxic effects of lead nitrate on human keratinocytes (HaCaT).
鉴定和表征类衣原体细菌Simkania negevensis的泛素E3 RING连接酶	Hörner, E.-M.	PDF	N/A	Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis
NEMF通过阻断PI3K/mTOR通路抑制卵巢癌细胞的增殖和迁移。	Wang, Q.	PDF	N/A	NEMF inhibits proliferation and migration of ovarian cancer cells by blocking the PI3K/mTOR pathway
R-Spondin模拟物，SZN-043，诱导增殖和Wnt活性，这两个特征在人类酒精相关性肝病中缺失	Fisher, T.	PDF	N/A	R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease
MCC：应用于结核分枝杆菌的基因组规模自动化质量和电荷校正	Mostolizadeh, R.	PDF	N/A	MCC: Automated Mass and Charge Curation at Genome-Scale Applied to C. tuberculostearicum
言语运动皮层使BCI光标控制和点击成为可能	Singer-Clark, T.	PDF	N/A	Speech motor cortex enables BCI cursor control and click
言语运动皮层使BCI光标控制和点击成为可能。	Singer-Clark, T.	PDF	N/A	Speech motor cortex enables BCI cursor control and click
血浆中失调蛋白质区分综合征性与非综合征性遗传性胸主动脉疾病	Seim, B. E.	PDF	N/A	Dysregulated Proteins in Plasma Distinguishing Syndromic from Non-syndromic Heritable Thoracic Aortic Disease
抗真菌药物5-氟胞嘧啶是尿道致病性大肠杆菌的毒力抑制剂，并能与β-内酰胺类药物协同作用，根除生物膜嵌入的细菌。	Ravishankar, S.	PDF	N/A	The antimycotic 5-fluorocytosine is a virulence inhibitor of uropathogenic Escherichia coli and eradicates biofilm-embedded bacteria synergizing with β-lactams
了解纤维素分解厌氧菌C. thermocellum对生物质解构的动态过程	Yarbrough, J.	PDF	N/A	Understanding the Dynamics of Biomass Deconstruction by the Cellulolytic Anaerobe C. thermocellum
由温度传感器HktS-HktR介导的丁香假单胞菌猕猴桃致病变种的毒力和运动性	Xiao, Y.	PDF	N/A	The virulence and motility of Pseudomonas syringae pv. Actinidiae mediated by a temperature sensor HktS-HktR
StratPal：一个用于创建地层古生物学建模管道的R包	Hohmann, N.	PDF	N/A	StratPal: An R package for creating stratigraphic paleobiology modeling pipelines
Lewy-MSA混合折叠驱动独特的神经元a-突触核蛋白病理	Enomoto, M.	PDF	N/A	Lewy-MSA hybrid fold drives distinct neuronal a-synuclein pathology
通过整合作物生长模型与全基因组预测，预测玉米杂交种子生产中自交系亲本在开花期的同步性	Laurent, A.	PDF	N/A	Predicting inbred parent synchrony at flowering for maize hybrid seed production by integrating crop growth model with whole genome prediction
先进鞋类技术训练8周后的足部特异性生物力学和能量反应	Matties, J. R.	PDF	N/A	Footwear-specific biomechanical and energetic responses to 8 weeks of training in advanced footwear technology
评估新西兰素食者的蛋白质摄入量和蛋白质质量	Soh, B. X. P.	PDF	N/A	Evaluation of protein intake and protein quality in New Zealand vegans
刺激位于尾侧额上回的额斜束起始部，会独立于效应器改变正在进行中的自发节律性活动。此结论基于纤维束成像引导下的经颅磁刺激实验证据。	Tagliaferri, M.	PDF	N/A	Stimulation of the Frontal Aslant Tract's origin in the caudal superior frontal gyrus alters ongoing spontaneous rhythmic activity independently from the effector. Evidence from tractography-guided Transcranial Magnetic Stimulation.
建模前生物起源的调控与代理在演化原细胞生态系统中的作用	Shirt-Ediss, B.	PDF	N/A	Modelling the prebiotic origins of regulation & agency in evolving protocell ecologies
建模新宿主中的山松甲虫丰度	Xie, X.	PDF	N/A	Modeling Mountain Pine Beetle Abundance in Novel Hosts
外周单核细胞中与祖先特异性基因表达相关的风险因素与神经退行性疾病的发生有关。	Wagen, A. Z.	PDF	N/A	Ancestry-specific gene expression in peripheral monocytes mediates risk of neurodegenerative disease
双酚A及六种数据不足的类似物的人体内暴露量通过多模式参数化的生理学基础动力学模型预测	Bigonne, H.	PDF	N/A	Human internal exposures of bisphenol A and six data-poor analogues predicted by physiologically based kinetic models with multimodal parameterization
左室致密化不全心肌病小鼠模型中的心脏电异常	de la Pompa, J. L.	PDF	N/A	Cardiac electrical abnormalities in a mouse model of left ventricular non-compaction cardiomyopathy
植物化学成分及药理学评价：榕叶对氧化应激、镇痛、腹泻及小鼠模型中血液凝固的影响	Labu, Z. K.	PDF	N/A	Phytochemical and Therapeutic Evaluation of Ficus nervosa Leaves: Impact on Oxidative Stress, Analgesic, Diarrhea, and Blood Clotting in a Mice Model
多巴胺与健康相关因素在脑认知差距中的作用：基于人工智能的功能连接组预测的见解	Esmaeili, M.	PDF	N/A	Brain-Cognitive Gaps in relation to Dopamine and Health-related Factors: Insights from AI-Driven Functional Connectome Predictions
用于通过正电子发射断层扫描成像移植的一对同基因小鼠，使用抗转铁蛋白受体纳米抗体	Balligand, T.	PDF	N/A	A pair of congenic mice for imaging of transplants by positron emission tomography using anti-transferrin receptor nanobodies
酵母菌喜欢托儿所，而霉菌则偏爱私人住宅。	Kauserud, H.	PDF	N/A	Yeasts prefer daycares and molds prefer private homes
体外和体内研究针对克隆ST512的肺炎克雷伯菌临床菌株的噬菌体疗法医疗产品（PTMPs）	Bleriot, I.	PDF	N/A	Studies in vitro e in vivo of Phage Therapy Medical Products (PTMPs) targeting clinical strains of Klebsiella pneumoniae belonging to the clone ST512
使用比较有限元分析测试颅骨功能假说：三种方法揭示了不同的结果	Mitchell, D. R.	PDF	N/A	Testing hypotheses of skull function with comparative finite element analysis: three methods reveal contrasting results
神经生长因子和锌螯合剂的联合递送显著促进了视神经挤压模型中的轴突再生	NGUYEN, H. Q. D.	PDF	N/A	Co-delivery of neurotrophic factors and a zinc chelator substantially promotes axon regeneration in the optic nerve crush model
一种网络正则化的线性模型，用于推断单细胞的空间表达模式	Gu, C.	PDF	N/A	A network regularized linear model to infer spatial expression pattern for single cell
使用共振光散射技术观察皮摩尔级蛋白质的展开过程	Alvarez, A. B.	PDF	N/A	Observing picomolar protein unfolding using resonance light scattering
微生物组蛋白质组分配揭示了饮食和代谢菌群失调如何影响疾病	Tibocha-Bonilla, J. D.	PDF	N/A	Proteome allocation of the microbiome reveals how diet and metabolic dysbiosis impact disease
通过消除与病毒Fc受体gE/gI的相互作用，提高抗体介导的对HSV感染的保护作用	Slein, M. D.	PDF	N/A	Improving antibody-mediated protection against HSV infection by eliminating interactions with the viral Fc receptor gE/gI
遗传筛选发现细胞壁酶是弗朗西斯菌属土拉热菌在淡水环境中生存的关键	Macaraeg, A.	PDF	N/A	Genetic screen identifies cell wall enzyme is key for freshwater survival of Francisella tularensis
rapgef1b在神经嵴特化及体节中胚层模式形成中的发育功能	Prasad, T.	PDF	N/A	Developmental functions of rapgef1b in neural crest specification and presomitic mesoderm patterning
本科生研究项目在美国东北部发现了一种新型两栖动物壶菌	Duryea, M. C.	PDF	N/A	Undergraduate research project uncovers a novel strain of amphibian chytrid fungus in the Northeastern United States
深海一次性鱿鱼种群的调控受表层水域的生态条件和深层鲸类捕食的影响。	Rademaker, M.	PDF	N/A	Population regulation in semelparous deep-sea squid is driven by ecological conditions in surface waters and whale predation at depth
大型亚热带河流中野生鱼类肠道微生物的变量系统发育和共演化模式	Liu, Y.	PDF	N/A	Variable phylosymbiosis and cophylogeny patterns in wild fish gut microbiota in a large subtropical river
家猫性连锁橙色毛色的分子和遗传特征	Kaelin, C. B.	PDF	N/A	Molecular and genetic characterization of sex-linked orange coat color in the domestic cat
PERCEPTIVE：一种用于预测新物种中表观遗传调控因子的R Shiny管道	Small, E. M.	PDF	N/A	PERCEPTIVE: an R Shiny pipeline for the prediction of epigenetic modulators in novel species
一个用于结构解释DMS反应性的定量框架	Deenalattha, S.	PDF	N/A	A quantitative framework for structural interpretation of DMS reactivity
LYCHOS-mTORC1通路中胆固醇感应的结构见解	Yu, S.	PDF	N/A	Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway
计算分析以评估降主动脉瘤中的血流动力学力	Duca, F.	PDF	N/A	Computational analysis to assess hemodynamic forces in descending thoracic aortic aneurysms
高跟鞋穿着下过度肌肉协同收缩对坐立表现的影响	Naik, G.	PDF	N/A	The Impact of Excessive Muscle Co-contraction on Sit-to-Stand Performance in High-Heeled Footwear
组织工程中的可解释人工智能：使用XGBoost和SHAP评估PLGA支架的生物相容性	Rafat, M. T.	PDF	N/A	Interpretable AI in Tissue Engineering: XGBoost and SHAP for PLGA Scaffold Biocompatibility
步骤：利用全转录组覆盖解码单细胞水平的空间图谱	Hu, Z.	PDF	N/A	STEP: Deciphering Spatial Atlas at Single-Cell Level with Whole-Transcriptome Coverage
通路火山图：一种用于通路引导的差异表达数据可视化交互工具	OConnell, T. M.	PDF	N/A	Pathway Volcano: An interactive tool for pathway guided visualization of differential expression data
膀胱的开源神经动力学模型	Lister, E.	PDF	N/A	An Open-Source Neurodynamic Model of the Bladder
PyEvoCell：一个增强型大型语言模型单细胞轨迹分析仪表盘	Mathur, S.	PDF	N/A	PyEvoCell: An LLM- Augmented Single Cell Trajectory Analysis Dashboard
使用穷尽投影寻踪进行自动表型分析	Moore, W. A.	PDF	N/A	Automatic Phenotyping Using Exhaustive Projection Pursuit
将空间药物异质性与微生物生长动力学在理论和实验中联系起来	Hu, Z.	PDF	N/A	Linking spatial drug heterogeneity to microbial growthdynamics in theory and experiment
多药外排泵EmrE的C端通过门控运输防止质子泄漏。	Brousseau, M.	PDF	N/A	The C-terminus of the multi-drug efflux pump EmrE prevents proton leak by gating transport
抗原灵活性在抗原密度较低时支持血凝素特异性抗体的亲和力	Benegal, A. N.	PDF	N/A	Antigen flexibility supports the avidity of hemagglutinin-specific antibodies at low antigen densities
在糖尿病条件下，缝隙连接的减弱并不会导致功能性β细胞亚群的丧失。	Levitt, C. H.	PDF	N/A	Diminished gap junction coupling under diabetogenic conditions does not drive loss of functional β-cell sub-populations
协调的蛋白质模块定义了在人卵巢癌模型中单细胞分辨率下对卡铂DNA损伤反应	Bedia, J. S.	PDF	N/A	Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models
急性葡萄糖摄取抑制下的代谢适应性变化集中于线粒体呼吸，以实现白血病细胞的生存。	Komza, M.	PDF	N/A	Metabolic Adaptations To Acute Glucose Uptake Inhibition Converge Upon Mitochondrial Respiration For Leukemia Cell Survival
电动自行车骑行：在运动强度领域中的代谢评估	Bonardi, A.	PDF	N/A	E-bike riding: A metabolic evaluation in the context of exercise intensity domains
急性耐力运动对骨骼肌选择性剪接的影响	Ahn, A.	PDF	N/A	The Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle
生菜在低温与强光联合胁迫下持续的非光化学淬灭及PSII修复循环的调控	Lempiainen, T.	PDF	N/A	Sustained non-photochemical quenching and regulation of PSII repair cycle during combined low temperature and high light stress in lettuce
高质量的荨麻（Urtica dioica ssp. dioica）分阶段基因组组装	Hirabayashi, K.	PDF	N/A	A high-quality phased genome assembly of stinging nettle, Urtica dioica ssp. dioica
兔形目头颅生物力学及其独特开窗鼻骨的功能意义	Wood-Bailey, A. P.	PDF	N/A	Lagomorph cranial biomechanics and the functional significance of the unique fenestrated rostrum of leporids
在识别同种巢寄生虫的卵方面，机器学习优于人类评估。	Hughes, A. E.	PDF	N/A	Machine learning outcompetes human assessment in identifying eggs of a conspecific brood parasite
基于构象集合的框架能够快速开发拉沙病毒疫苗候选者	Mishra, N.	PDF	N/A	Conformational ensemble-based framework enables rapid development of Lassa virus vaccine candidates
表达皮肤蛋白的成纤维细胞介导了皮肤巨噬细胞微环境的关键作用	Vollmers, A. C.	PDF	N/A	Dermatopontin-expressing fibroblasts mediate an essential skin macrophage niche
肥大细胞质膜中拓扑结构与脂质域的协同作用控制信号蛋白的定位，并促进其协同激活	Ghosh, S.	PDF	N/A	The Synergy between Topography and Lipid Domains in the Plasma Membrane of Mast Cells Controls the Localization of Signaling Proteins and Facilitates their Coordinated Activation
M2巨噬细胞是子宫内膜异位症种系风险的主要介质，并解释了其与共病特征的多效性	Ochoa, S.	PDF	N/A	M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits
自然杀伤细胞功能障碍驱动瘢痕疙瘩发病机制	Zhao, Y.	PDF	N/A	Natural killer cell dysfunction drives keloid pathogenesis
在非常罕见的祖B细胞条件下，多样化的启动结果	Madden, P. J.	PDF	N/A	Diverse priming outcomes under conditions of very rare precursor B cells
伯克霍尔德菌属（Burkholderia cenocepacia）蛋白质O-连接糖基化生物合成的晚期步骤具有条件性必需性。	Jebeli, L.	PDF	N/A	The Late-Stage Steps of Burkholderia cenocepacia Protein O-Linked Glycan Biosynthesis Are Conditionally Essential.
沙门氏菌致病岛1编码的小RNA InvR介导了激活因子HilA在沙门氏菌中的转录后反馈调控。	Hou, Y.	PDF	N/A	The Salmonella pathogenicity island 1-encoded small RNA InvR mediates post-transcriptional feedback control of the activator HilA in Salmonella
多模态CRISPR筛选揭示DDX39B为全局抑制A-to-I RNA编辑的因子	Wei, T.	PDF	N/A	Multimodal CRISPR screens uncover DDX39B as a global repressor of A-to-I RNA editing
小鼠造血干细胞自我更新和分化在原生造血中的克隆分析	You, C.	PDF	N/A	Clonal analysis of murine HSC self-renewal and differentiation in native hematopoiesis
性状空间的模式由突变的速率和方式决定。	Martis, S.	PDF	N/A	Trait-space patterning is dictated by the tempo and mode of mutation
神经元中Imp的丧失通过Syndecan功能引发癫痫行为	Roy, P. R.	PDF	N/A	Loss of neuronal Imp induces seizure behavior through Syndecan function
利用机械进化模型识别基因组对当地气候的适应性	Goel, N.	PDF	N/A	Identifying genomic adaptation to local climate using a mechanistic evolutionary model
两种入侵性球蚜物种（铁杉球蚜和菠萝瘿球蚜）的基因组使得对烟碱型乙酰胆碱受体的特性描述成为可能。	Glendening, A. M.	PDF	N/A	Genomes of two invasive Adelges species (hemlock woolly adelgid and pineapple gall adelgid) enable characterization of nicotinic acetylcholine receptors
从养殖鹿监控计划中进行尸检时分离出的白尾鹿（Odocoileus virginianus）大肠杆菌（Escherichia coli）的系统地理学模式	Metrailer, M. C.	PDF	N/A	Phylogeographic patterns of Escherichia coli isolated from white-tailed deer, Odocoileus virginianus , during necropsy in a farmed deer surveillance program
低温电子显微镜揭示AAA+ ATP酶Thorase的新型螺旋丝形成结构	Dar, M. A.	PDF	N/A	Cryo-EM Structure of AAA + ATPase Thorase Reveals Novel Helical Filament Formation
关键通路基因的异源表达导致Paraburkholderia sacchari ITP 101中生物塑料前体产量增加的复杂模式	Morris, D.	PDF	N/A	Heterologous expression of critical pathway genes leads to complex pattern of increased yield of bioplastic precursors in Paraburkholderia sacchari ITP 101
未经过抗体修饰的模拟心磷脂的脂质纳米颗粒，实现了体内CAR-T细胞的衰老清除疗法，用于炎症性衰老的治疗。	Zhang, Z.	PDF	N/A	Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in-vivo CAR-T therapy for inflamm-aging
BioLLM：一个用于整合和基准测试单细胞基础模型的标准化框架	Qiu, P.	PDF	N/A	BioLLM: A Standardized Framework for Integrating and Benchmarking Single-Cell Foundation Models
调和竞争模型：凝聚物与可溶复合物在转录因子功能中的作用	Bremer, A.	PDF	N/A	Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function
研究光系统II中TyrD、TyrZ和QA-形成引起的Soret区域电致变色带移	Boussac, A.	PDF	N/A	Investigation of electrochromic band-shifts in the Soret region induced by the formation of TyrD, TyrZ, and QA- in Photosystem II
SFPQ-TFE3基因融合相互调节mTORC1活性，并在一种新型小鼠肾肿瘤发生模型中诱导谱系可塑性	Asrani, K.	PDF	N/A	SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis
谷氨酰胺补充对饮食诱导肥胖小鼠代谢紊乱、肠道屏障功能及肠道菌群的性别依赖性影响。	Lefebvre, C.	PDF	N/A	Sex-dependent effects of a glutamine supplementation on metabolic disorders, intestinal barrier function and gut microbiota in mice with diet-induced obesity.
光依赖型乙醇同化作用：模型红藻球石藻（Galdieria sulphuraria）的研究	Bolychevtseva, Y. V.	PDF	N/A	Light-Dependent Ethanol Assimilation By Model Red Microaga Galdieria sulphuraria
靶向CRISPR筛选揭示了在宿主肠道中维持隐孢子虫生存的关键基因	Watson, L. C.	PDF	N/A	Targeted CRISPR Screens Reveal Genes Essential for Cryptosporidium Survival in the Host Intestine
痘病毒诱导细胞质形成类似核环境，以促进病毒复制。	Veratti, P.	PDF	N/A	Poxviruses induce a nuclear environment in the cytoplasm to promote viral replication
噬菌体共培养法：通过共培养实现噬菌体的靶向发现	Rand, E. A.	PDF	N/A	Phage DisCo: targeted discovery of bacteriophages by co-culture
酵母杀伤毒素K2的丙氨酸扫描揭示了活性关键残基、获得功能变体，并支持前体加工和三维结构的预测。	Prins, R. C.	PDF	N/A	Alanine-scanning of the yeast killer toxin K2 reveals key residues for activity, gain-of-function variants, and supports prediction of precursor processing and 3D structure.
通过多样性驱动的刺突选择来表征α冠状病毒的表型特征	Gallo, G.	PDF	N/A	Characterising alphacoronavirus phenotypic traits through diversity-driven selection of spike
对连续采样的家庭队列进行深度测序揭示了Omicron SARS-CoV-2在宿主体内的动态变化及罕见的新型刺突变异体的选择	Bendall, E. E.	PDF	N/A	In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants
碳酸酐酶在土壤细菌泰国伯克霍尔德菌E264引起的岩石风化和pH调节中的作用	Bell, D. S.	PDF	N/A	The role of carbonic anhydrase in rock weathering and pH regulation by the soil bacterium Burkholderia thailandensis E264
GraFusionNet：融合节点、边和语义特征以增强图表示	Tahmid, M. T.	PDF	N/A	GraFusionNet: Integrating Node, Edge, and Semantic Features for Enhanced Graph Representations
绘制内体近端蛋白组图谱揭示Retromer作为RAB GTPase调控的枢纽。	Anton-Plagaro, C.	PDF	N/A	Mapping the endosomal proximity proteome reveals Retromer as a hub for RAB GTPase regulation.
病原体传播中的性别偏见是由热塑性决定的：热塑性决定了性别偏见在病原体传播中的作用。	Butterworth, N. J.	PDF	N/A	The sicker sex is plastic: Thermal plasticity determines sex biases in pathogen transmission
无花果微型群落的细菌	Woodruff, G. C.	PDF	N/A	The Bacteria of a Fig Microcommunity
从Pool-Seq数据估计层次F统计量	Gautier, M.	PDF	N/A	Estimating hierarchical F-statistics from Pool-Seq data
TelSPRITE揭示的ALT细胞中的端粒相互作用和结构变异	Wilson, D. G.	PDF	N/A	Telomere interactions and structural variants in ALT cells revealed with TelSPRITE
一种对Trichogramma kaykai的参考基因组：一种生活在沙漠中的小型寄生蜂，具有竞争性的性比破坏者	Culotta, J.	PDF	N/A	A reference genome for Trichogramma kaykai: A tiny desert-dwelling parasitoid wasp with competing sex-ratio distorters
HiC2Self：用于批量和单细胞Hi-C接触图的自监督去噪	Yang, R.	PDF	N/A	HiC2Self: self-supervised denoising for bulk and single-cell Hi-C contact maps
一种用于自主控制啮齿动物行为的模块化门控系统	Lester, A. W.	PDF	N/A	A modular gate system for autonomous control of rodent behavior
利用隐马尔可夫模型在斑马鱼幼体运动中关联大脑和行为状态	Dommanget-Kott, M.	PDF	N/A	Linking Brain and Behavior States in Zebrafish Larvae Locomotion using Hidden Markov Models
跨进化群的RND多药外排泵的构象可塑性及其对底物特异性的影响	Lazarova, M.	PDF	N/A	Conformational plasticity across phylogenetic clusters of RND multidrug efflux pumps and its impact on substrate specificity
榛子非特异性脂质转移蛋白Cor a 8是一种具有新脂酶活性的兼职酶。	Fissore, A.	PDF	N/A	Corylus avellana non-specific lipid-transfer protein Cor a 8 is a moonlighting enzyme with a new lipase activity
diaPASEF驱动的化学蛋白质组学实现了深度激酶组相互作用分析	Woods, K.	PDF	N/A	diaPASEF-Powered Chemoproteomics Enables Deep Kinome Interaction Profiling
14-3-3结合维持与帕金森病相关的激酶LRRK2处于失活状态。	Martinez Fiesco, J. A.	PDF	N/A	14-3-3 binding maintains the Parkinson's associated kinase LRRK2 in an inactive state
基于两株禽源致病性大肠杆菌的基因组组装与注释比较	Zhao, Y.	PDF	N/A	Comparison of genomic assembly and annotation based on two clones of avian pathogenic Escherichia coli
HGTs并非SPRs：在存在幽灵分支的情况下，一系列水平基因转移并不会导致一系列子树修剪和嫁接	Tricou, T.	PDF	N/A	HGTs are not SPRs: In the presence of ghost lineages, series of Horizontal Gene Transfers do not result in series of Subtree Pruning and Regrafting
EXO5基因中的一种常见单体型可以影响其蛋白质结构和动力学，并调节基因组稳定性和癌症进展。	Mazza, F.	PDF	N/A	A common haplotype in the EXO5 gene can impact its protein structure and dynamics and modulate genome stability and cancer progression
Roquin通过其两个ROQ结构域结合位点对RNA茎环稳定性表现出相反的作用。	Tants, J.-N.	PDF	N/A	Roquin exhibits opposing effects on RNA stem-loop stability through its two ROQ domain binding sites
结构导向的突变揭示了多囊蛋白-2/多囊蛋白-1异二聚体的离子通道功能	Staudner, T.	PDF	N/A	Ion channel function of polycystin-2/polycystin-1 heteromer revealed by structure-guided mutagenesis
在细胞色素bc1的Qo位点，通过冗余网络进行氧化还原激活的质子转移	Arantes, G. M.	PDF	N/A	Redox-Activated Proton Transfer through a Redundant Network in the Qo Site of Cytochrome bc1
所有血小板整合素的耗竭会影响止血、血栓形成和肿瘤转移。	Janus-Bell, E.	PDF	N/A	Depletion of all platelet integrins impacts hemostasis, thrombosis and tumor metastasis
妊娠期间Hofbauer细胞对HIV和CMV的不同免疫反应突显了不断变化的胎盘免疫动态	Schuch, V.	PDF	N/A	Distinct immune responses to HIV and CMV in Hofbauer cells across gestation highlight evolving placental immune dynamics
揭示根际中促进适应性的遗传联系	Williams, J. L.	PDF	N/A	Uncovering genetic linkages in the rhizosphere contributing to adaptation
使用TubeTracker进行半自动高内涵花粉性能分析	Yimga Ouonkap, S. V.	PDF	N/A	Semi-automated high content analysis of pollen performance using TubeTracker
乙醇通过BK钾离子通道以一种新颖的机制改变了秀丽隐杆线虫的机械感觉习惯化。	Kokan, N.	PDF	N/A	Ethanol alters mechanosensory habituation in C. elegans by way of the BK potassium channel through a novel mechanism
性别、交配状态和遗传背景对果蝇昼夜节律行为的影响	Akpoghiran, O.	PDF	N/A	Effects of sex, mating status, and genetic background on circadian behavior in Drosophila
通过超图模型进行高阶相互作用分析，以研究多维神经科学数据。	Bilbao, D.	PDF	N/A	Higher-Order Interaction Analysis via Hypergraph Models for Studying Multidimensional Neuroscience Data.
通过拮抗检测器实现高效的信息素导航	Wan, X.	PDF	N/A	Efficient pheromone navigation via antagonistic detectors
通过电信号标记解读动机状态和渴望：神经“读心术”	Proverbio, A. M.	PDF	N/A	Decoding Motivational States and Craving through Electrical Markers for Neural 'Mind Reading'
胼胝体间相位对齐的β爆发的产生是TMS诱导的半球间抑制的基础	Georgiev, C.	PDF	N/A	Transcallosal generation of phase aligned beta-bursts underlies TMS-induced interhemispheric inhibition
在人类恢复视力后，腹侧视觉皮层中的视觉和听觉对象表征	Raczy, K.	PDF	N/A	Visual and auditory object representations in ventral visual cortex after restoring sight in humans
通过基于邻近的蛋白质组学发现揭示了电突触分子的多样性	Michel, J. C.	PDF	N/A	Electrical synapse molecular diversity revealed by proximity-based proteomic discovery
由自闭症风险基因DDX3X突变引起的神经发育的性别特异性扰动	Mossa, A.	PDF	N/A	Sex-specific perturbations of neuronal development caused by mutations in the autism risk gene DDX3X
丁丙诺啡诱导人胎膜无菌性炎症	Lynn, T.	PDF	N/A	Buprenorphine Induces Human Fetal Membrane Sterile Inflammation
来自加拿大生长的白香草木犀（Melilotus albus，白甜苜蓿）根瘤中分离得到的一种新型非共生细菌，命名为Phyllobacterium meliloti sp. nov.。	Bromfield, E. S. P.	PDF	N/A	Phyllobacterium meliloti sp. nov. a novel non-symbiotic bacterium isolated from root nodules of Melilotus albus (white sweet clover) grown in Canada
在胚胎关键期，线粒体活性氧和HIF1-alpha信号的保守作用指导了随后神经系统的发展。	Sobrid-Camean, D.	PDF	N/A	Conserved mitochondrial reactive oxygen species and HIF1-alpha signalling during an embryonic critical period directs subsequent nervous system development
背腹表面的机械耦合塑造了果蝇的平衡棒	Song, Y.	PDF	N/A	Mechanical coupling between dorsal and ventral surfaces shapes the Drosophila haltere
五聚体氯离子通道BEST1被胞外GABA激活	Pant, S.	PDF	N/A	The pentameric chloride channel BEST1 is activated by extracellular GABA
电路模型中归一化强度的神经元异质性	Song, D.	PDF	N/A	Neuronal heterogeneity of normalization strength in a circuit model
利用扩散成像和纤维束成像评估单侧6-羟多巴胺帕金森病大鼠模型中全脑结构连接的变化	Moshchin, M.	PDF	N/A	Assessing changes in whole-brain structural connectivity in the unilateral 6-hydroxydopamine rat model of Parkinson's Disease using diffusion imaging and tractography
句子生成过程中语义结构的神经编码	Giglio, L.	PDF	N/A	Neural Encoding of Semantic StructuresDuring Sentence Production
# BioRxiv 2024-11-21 Papers

标题	作者	PDF链接	代码仓库	Title
长期胞外记录中神经活动追踪的通用框架	Chaure, F. J.	PDF	N/A	General Framework for Tracking Neural Activity Over Long-Term Extracellular Recordings
岛叶和颞上沟在社交决策中对人际内疚感和责任感的作用	Gaedeke, M.	PDF	N/A	Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions
撤回：KMT5C 通过有限的序列特征编码了强健的异染色质保留和液态样行为	Strickfaden, H.	PDF	N/A	WITHDRAWN: KMT5C encodes robust heterochromatin retention and liquid-like behavior using limited sequence features
FET融合癌蛋白在癌症中破坏生理性DNA修复网络	Menon, S.	PDF	N/A	FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer
E3连接酶HvST1功能的丧失显著增加了重组	Orr, J. N.	PDF	N/A	Loss of E3 ligase HvST1 function substantially increases recombination
在半自然条件下饲养的小鼠群体中建模集体行为	Chen, X.	PDF	N/A	Modelling collective behavior in groups of mice housed under semi-naturalistic conditions
在慢性癫痫期间短暂暴露于托法替尼后的疾病修饰作用。	Hoffman, O. R.	PDF	N/A	Disease modification upon brief exposure to tofacitinib during chronic epilepsy.
推动基于光泵磁力计的脑磁图技术在早期人类生命中的应用边界	Corvilain, P.	PDF	N/A	Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life
超特化灵长类动物拥有一套缩减的异生物质代谢细胞色素P450基因。	Chaney, M. E.	PDF	N/A	Hyper-specialized primates possess a reduced suite of xenobiotic-metabolizing cytochrome P450 genes.
细胞色素P450 CYP72A1182在苋菜（Amaranthus palmeri）种群中代谢型除草剂抗性进化中的作用	Rigon, C. A. G.	PDF	N/A	Function of Cytochrome P450 CYP72A1182 in Metabolic Herbicide Resistance Evolution in Amaranthus palmeri Populations
脊髓感觉运动回路在三相指令中的作用：使用目标探索过程的模拟方法	Cattaert, D.	PDF	N/A	Role of spinal sensorimotor circuits in triphasic command: a simulation approach using Goal Exploration Process
人类肠道微生物群中普遍存在的定向选择	Wolff, R.	PDF	N/A	Pervasive selective sweeps across human gut microbiomes
通过集体迁徙实现的非遗传性适应	Vo, L.	PDF	N/A	Non-genetic adaptation by collective migration
推断在共进化动力学过程中产生的噬菌体-细菌相互作用表型的菌株水平突变驱动因素	Lucia-Sanz, A.	PDF	N/A	Inferring strain-level mutational drivers of phage-bacteria interaction phenotypes arising during coevolutionary dynamics
最小化蛋白质组再分配解释了碳源分级利用中的代谢转变	Liu, Z.	PDF	N/A	Minimization of proteome reallocation explains metabolic transition in hierarchical utilization of carbon sources
利用蛋白质拆分重组策略调控PLD酶活性	yao, y.	PDF	N/A	Using split protein reassembly strategy to control PLD enzymatic activity
双胞胎的故事：胞内与胞外甲酸盐在调控鼠伤寒沙门氏菌鞭毛及毒力岛-1基因中的不同角色	MUKHERJEE, D.	PDF	N/A	A Tale of Twins: The Distinct Roles of Intracellular and Extracellular Formate in Regulating Flagellar and Pathogenicity Island-1 Genes in Salmonella Typhimurium
谷氨酸能突触表型的睡眠需求驱动振荡	Vogt, K.	PDF	N/A	Sleep need driven oscillation of glutamatergic synaptic phenotype
中性转录组重塑促进物种水平上的QDR进化能力	Delplace, F.	PDF	N/A	Neutral transcriptome rewiring promotes QDR evolvability at the species level
靶向EGFR配体Epiregulin的抗体药物偶联物在结直肠癌中展现出强大的抗肿瘤活性	Jacob, J.	PDF	N/A	Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
听觉系统中灵活的巧合检测的解剖学和生理学基础	Kreeger, L. J.	PDF	N/A	An Anatomical and Physiological Basis for Flexible Coincidence Detection in the Auditory System
增加第5层Martinotti细胞的兴奋性会降低锥体细胞群体的可塑性，并改善运动执行能力。	Malfatti, T.	PDF	N/A	Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves motor execution
自适应分块提高了前额叶皮层和基底神经节回路中的有效工作记忆容量。	Soni, A.	PDF	N/A	Adaptive chunking improves effective working memory capacity in a prefrontal cortex and basal ganglia circuit
盐胁迫下根冠比的自然变异揭示了SR3G作为拟南芥根木栓质化和盐耐受性的负调控因子	Ishka, M. R.	PDF	N/A	Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis
一个跨物种框架，用于研究感知证据的积累	Chakravarty, S.	PDF	N/A	A cross-species framework for investigating perceptual evidence accumulation
单细胞转录组特征分析（SCOTCH）：通过长读长单细胞RNA测序进行基因表达的转录本水平特征分析	Xu, Z.	PDF	N/A	Single-Cell Omics for Transcriptome CHaracterization (SCOTCH): isoform-level characterization of gene expression through long-read single-cell RNA sequencing
海马体涟漪预示人类在短暂休息期间的运动学习	Sjogard, M.	PDF	N/A	Hippocampal ripples predict motor learning during brief rest breaks in humans
当药物抗性突变率不同时的最佳抗菌药物组合	Delaney, O.	PDF	N/A	Optimal antimicrobial dosing combinations when drug-resistance mutation rates differ
一种关于等频和跨频神经耦合的新视角：大脑网络功能的整合与分离	Mateos, D. M.	PDF	N/A	A novel perspective on equal and cross-frequency neural coupling: integration and segregation of the brain networks' function
基于力矩臂的梯度指定优化自动肌肉路径校准	Chen, Z.	PDF	N/A	Automated muscle path calibration with gradient-specified optimization based on moment arm
早期视觉皮层和面部选择性脑区中空间选择性的常见模式	Morsi, A. Y.	PDF	N/A	Common patterns of spatial selectivity in early visual cortex and face-selective brain regions
利用深度学习剖析转录起始的顺式调控语法	Cochran, K.	PDF	N/A	Dissecting the cis-regulatory syntax of transcription initiation with deep learning
纹状体胆碱能中间神经元的暂停反应需要Kv1通道，在运动障碍小鼠中缺失，并通过多巴胺D5受体反向激动作用得以恢复	Tubert, C.	PDF	N/A	Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism
一种基于代理的肿瘤生长建模框架，整合了细胞动力学的机械和进化方面	Macnamara, C. K.	PDF	N/A	An agent-based modelling framework for tumour growth incorporating mechanical and evolutionary aspects of cell dynamics
表达Ly49受体家族中的单一抑制性成员足以使NK细胞获得效应功能。	Piersma, S. J.	PDF	N/A	Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions
支原体滑行运动中F1样ATP酶的二聚体组装	Toyonaga, T.	PDF	N/A	Dimeric assembly of F1-like ATPase for the gliding motility of Mycoplasma
双语语言处理依赖于共享的语义表征，这些表征受每种语言的调节。	Chen, C.	PDF	N/A	Bilingual language processing relies on shared semantic representations that are modulated by each language
大型溞全基因组DNA甲基化模式揭示了其靶向于启动子近端区域	Liu, R.	PDF	N/A	Genome-wide DNA Methylation Patterns in Daphnia magna Reveal Targeting to Promoter Proximal Regions
PTEN通过亚细胞定位调节瓣膜间质细胞中的肌成纤维细胞激活	Batan, D.	PDF	N/A	PTEN Regulates Myofibroblast Activation in Valvular Interstitial Cells based on Subcellular Localization
适应侧步控制以沿蜿蜒路径行走	Render, A. C.	PDF	N/A	Adapting Lateral Stepping Control to Walk on Winding Paths
长寿物种中本地适应性的演变	Habluetzel, L.	PDF	N/A	The evolution of local adaptation in long-lived species
PA28γ通过C1QBP提升线粒体功能，从而促进肿瘤的恶性进展。	Wang, J.	PDF	N/A	PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
单细胞自发荧光成像揭示了中性粒细胞在跨生物系统激活后立即发生的代谢转变	Datta, R.	PDF	N/A	Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems
人类可以利用正负光谱时间相关性来检测音调的上升和下降	Vaziri, P. A.	PDF	N/A	Humans can use positive and negative spectrotemporal correlations to detect rising and falling pitch
新型细胞外基质蛋白SNED1通过RGD结合整合素α5β1和αvβ3介导细胞粘附	Pally, D.	PDF	N/A	The novel ECM protein SNED1 mediates cell adhesion via the RGD-binding integrins α5β1 and αvβ3
肽段感知化学语言模型成功预测了环肽的膜扩散	Feller, A. L.	PDF	N/A	Peptide-aware chemical language model successfully predicts membrane diffusion of cyclic peptides
夜幕下的庇护：夜间躲避人工光源或可降低搁浅海鸟的风险	Brown, T. M.	PDF	N/A	Under Cover of Darkness: Refuge from Artificial Light at Night may Mitigate Risks to Stranded Seabirds
scatterbar：一个用于在空间解析坐标上可视化比例数据的R包	Velazquez, D.	PDF	N/A	scatterbar: an R package for visualizing proportional data across spatially resolved coordinates
神经生长因子受体跨膜螺旋相互作用的模拟揭示了活性状态和不同的信号传导机制	Athanasiou, C.	PDF	N/A	Simulation of neurotrophin receptor transmembrane helix interactions reveals active states and distinct signaling mechanisms
祖传功能的重新分配是海洋捕食性蜗牛毒液生产进化的基础	Zancolli, G.	PDF	N/A	Redistribution of ancestral functions underlies the evolution of venom production in marine predatory snails
一项横跨大陆的实验阐明了一种世界性植物在空间和时间上对气候的（不）适应性。	Albano, L. J.	PDF	N/A	A transcontinental experiment elucidates (mal)adaptation of a cosmopolitan plant to climate in space and time
在编码稀疏基因组的物种中，使用两步法从群体基因组数据推断人口统计学和选择历史：应用于人类数据	Soni, V.	PDF	N/A	Inferring demographic and selective histories from population genomic data using a two-step approach in species with coding-sparse genomes: an application to human data
肝线粒体呼吸对复杂III缺陷小鼠的正常体温维持至关重要，这些小鼠的棕色脂肪组织产热功能受损。	Banerjee, R.	PDF	N/A	Hepatic mitochondrial respiration is crucial for euthermia in complex III-deficient mice with impaired brown adipose tissue thermogenesis
在唐氏综合症B细胞急性淋巴母细胞白血病中，可以通过使用Venetoclax来针对其代谢脆弱性。	Jones, D.	PDF	N/A	Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax
表达嵌合细胞因子受体的巨噬细胞在IL-10或TGFβ刺激下表现出炎症表型并具有抗肿瘤活性。	Traxel, S.	PDF	N/A	Macrophages expressing chimeric cytokine receptors have an inflammatory phenotype and anti-tumoral activity upon IL-10 or TGFβ stimulation
用于双光子亚细胞钙成像的预处理工具箱	Jiang, A.	PDF	N/A	A preprocessing toolbox for 2-photon subcellular calcium imaging
与亚临床性淡漠相关的前运动回路	Derosiere, G.	PDF	N/A	Fronto-motor circuits linked to subclinical apathy
巨细胞病毒与脑萎缩对不同人群免疫衰老轨迹的影响	Touil, H.	PDF	N/A	Relation of CMV and brain atrophy to trajectories of immunosenescence in diverse populations
多成分营养补充剂与衰老小鼠的衰老干预具有可比的抗衰老功效	Brookes, C.	PDF	N/A	Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice
利用特征结构感知的直系同源分配方法，追踪植物细胞壁降解酶在整个生命树中的分类分布	Tran, V.	PDF	N/A	Tracing the taxonomic distribution of plant cell wall degrading enzymes across the tree of life using feature architecture aware orthology assignments
稳定感染重组卡波西肉瘤相关疱疹病毒的内皮细胞表现出独特的粘弹性和形态学特性。	Shabangu, M. M.	PDF	N/A	Endothelial cells stably infected with recombinant Kaposi's sarcoma-associated herpesvirus display distinct viscoelastic and morphological properties
象牙喙啄木鸟与蓝松鸦在频谱图层面的对比显示出差异	Williams, J. D.	PDF	N/A	Ivory-billed Woodpecker and Blue Jay kent comparisons at spectrogram level reveal differences
模拟微重力加速α-突触核蛋白聚集并诱导体外帕金森病模型中的氧化应激	Lentini, V.	PDF	N/A	Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model
《昆虫生物群落图集》数据：瑞典和马达加斯加陆生节肢动物的宏条形码调查	Miraldo, A.	PDF	N/A	Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar
Cloudgene 3：将Nextflow管道转化为强大的Web服务	Forer, L.	PDF	N/A	Cloudgene 3: Transforming Nextflow Pipelines into Powerful Web Services
人类精子发生导致核孔结构和功能的减少	dos Santos, A.	PDF	N/A	Human spermatogenesis leads to a reduced nuclear pore structure and function
纹状体胆碱能中间神经元的同步激活可诱导局部血清素释放。	Matityahu, L.	PDF	N/A	Synchronous activation of striatal cholinergic interneurons induces local serotonin release
注释冷冻电镜三维重构体积：一个机器学习挑战	Peck, A.	PDF	N/A	Annotating CryoET Volumes: A Machine Learning Challenge
微管动态由聚类原丝的构象和稳定性决定。	Kalutskii, M.	PDF	N/A	Microtubule dynamics are defined by conformations and stability of clustered protofilaments
通过溶解度改变探索组合疗法的作用机制：推进AML治疗	Gholizadeh, E.	PDF	N/A	Exploring Mechanisms of Action in Combinatorial Therapies through Solubility Alterations: Advancing AML Treatment
转录因子GABPA是原始多能性的主调控因子。	Zhou, C.	PDF	N/A	The transcription factor GABPA is a master regulator of naive pluripotency
动物编码的非核糖体途径合成布尔萨特林类似物	Venugopalan, A.	PDF	N/A	Animal-encoded nonribosomal pathway to bursatellin analogs
一种用于狨猴神经科学设备的开放获取资源	Rollin, I. Z.	PDF	N/A	An Open Access Resource for Marmoset Neuroscientific Apparatus
大规模衣壳介导的细菌基因组DNA在肠道微生物群中的移动	Borodovich, T.	PDF	N/A	Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
博茨瓦纳、加蓬、肯尼亚、南非和美国非洲象体内隐性感染的象内皮细胞嗜性疱疹病毒和象伽玛疱疹病毒	Pearson, V. R.	PDF	N/A	Quiescent Infections of Elephant Endotheliotropic Herpesviruses and Elephant Gammaherpesviruses in African Elephants in Botswana, Gabon, Kenya, South Africa and USA
撤回：通过计算优化和结构工程显著提高接枝纳米抗体的抗病毒疗效	HUO, L.	PDF	N/A	WITHDRAWN: Significantly enhancing antiviral efficacy by computational optimization and structural engineering of grafted nanobodies
基质硬度决定了人类肺成纤维细胞中独特的阿霉素诱导的衰老相关分泌表型和转录组特征	Du, H.	PDF	N/A	Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts
准备用于核型分析和荧光原位杂交（FISH）的高质量番红花属物种染色体铺展	El-nagish, A.	PDF	N/A	Preparing high-quality chromosome spreads from Crocus species for karyotyping and FISH
酶催化纤维蛋白网络的凝固性颗粒水凝胶用于内源性组织再生	Deng, Z.	PDF	N/A	Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration
单细胞空间映射揭示了在早期结直肠癌形成过程中细胞类型组成的改变及组织微环境的变迁	Guha, T. K.	PDF	N/A	Single-cell spatial mapping reveals alteration of cell type composition and tissue microenvironment during early colorectal cancer formation
慢性神经病理性疼痛对高效力μ型阿片受体激动剂芬太尼自我给药的影响	Burgess, G. E.	PDF	N/A	The effects of chronic neuropathic pain on the self-administration of highly potent MOR agonist, fentanyl
电荷介导的转化技术在高效植物基因组编辑中的应用	Augustine, S. M.	PDF	N/A	Electrical charge-mediated transformation for efficient plant genome editing
综合计算框架Dyscovr将突变驱动基因与19种癌症类型的表达失调联系起来	Geraghty, S. E.	PDF	N/A	Integrative Computational Framework, Dyscovr, Links Mutated Driver Genes to Expression Dysregulation Across 19 Cancer Types
开发新型外周神经袖带信号与峰电位速度分析工具	Klus, J.	PDF	N/A	Development of novel signal and spike velocity analysis tools in peripheral nerve cuffs
单变量和多变量fMRI分析揭示的被动手指运动的运动学特征的神经相关性	Pamplona, G. S. P.	PDF	N/A	Neural correlates of kinematic features of passive finger movement revealed by univariate and multivariate fMRI analyses
水生丛毛单胞菌（Comamonas aquatica）抑制TIR-1/SARM1诱导的轴突退化。	O'Connor, L. C.	PDF	N/A	Comamonas aquatica inhibits TIR-1/SARM1 induced axon degeneration
从TCR T细胞与癌细胞相互作用的活细胞成像中分析细胞行为	Verma, A.	PDF	N/A	Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions
Anillin 在 Rho 信号通路介导的紧密连接重塑过程中调节收缩力和屏障功能	Craig, Z.	PDF	N/A	Anillin tunes contractility and regulates barrier function during Rho flare-mediated tight junction remodeling
延迟蛋白质转运保护线粒体免受有毒的CAT尾蛋白的侵害	Bertram, N.	PDF	N/A	Delayed protein translocation protects mitochondria against toxic CAT-tailed proteins
工程化装配体以模拟移植物与宿主骨骼肌的相互作用	Rossi, L.	PDF	N/A	Engineering assembloids to mimic graft-host skeletal muscle interaction
不同人类冠状病毒的核衣壳（N）蛋白在诱导细胞质凝聚物形成的能力上表现出差异。	Tikhomirova, M. A.	PDF	N/A	The nucleocapsid (N) proteins of different human coronaviruses demonstrate a variable capacity to induce the formation of cytoplasmic condensates
一个基于过程的模型，模拟德国库蚊（Culex pipiens s.s./Cx. torrentium）的生命周期	Rauhöft, L.	PDF	N/A	A process-based model simulating the life cycle of Culex pipines s.s./Cx. torrentium in Germany
将野生鸣唱文化重新引入极度濒危的鸣禽中	Appleby, D. L.	PDF	N/A	Reintroduction of wild song culture to a critically endangered songbird
宿主特征和环境变异共同塑造了野生三刺鱼肠道微生物群的多样性	Härer, A.	PDF	N/A	Host traits and environmental variation shape gut microbiota diversity in wild threespine stickleback
不可穿越边界栖息地中的家域溢出：原因、偏差及使用自相关核密度估计的修正	Hollins, J. P. W.	PDF	N/A	Home range spillover in habitats with impassable boundaries: Causes, biases, and corrections using autocorrelated kernel density estimation
空间背景使植物对硝化作用的控制得以进化	Ardichvili, A. N.	PDF	N/A	Spatial context allows the evolution the control of nitrification by plants
刺胞动物机械感觉神经元细胞类型多样性的结构分子和发育学证据	Baranyk, J.	PDF	N/A	Structural molecular and developmental evidence for cell-type diversity in cnidarian mechanosensory neurons
尽管遗传差异的证据很少，但休眠和非休眠云杉芽虫株系之间的基因表达发生了重大变化。	van der Burg, K. R. L.	PDF	N/A	Major changes in gene expression between strains of diapausing and non-diapause spruce budworm despite little evidence of genetic divergence
利用数学约束条件解释等位基因共享差异的狭窄范围	Liu, X.	PDF	N/A	Using mathematical constraints to explain narrow ranges for allele-sharing dissimilarities
ERGA-BGE 北山羊（Rupicapra rupicapra）参考基因组：欧洲最丰富的山地有蹄类动物	Buzan, E.	PDF	N/A	ERGA-BGE Reference Genome of the Northern chamois (Rupicapra rupicapra): Europe's most abundant mountain ungulate
利用视频技术进行深度学习作为测量家禽感染的工具	Scheidwasser, N.	PDF	N/A	Deep learning from videography as a tool for measuring infection in poultry
超镁铁质岩石生物加速风化性能的跨物种比较	Plante, L.	PDF	N/A	Cross-species Comparison of Ultramafic Rock Bio-accelerated Weathering Performance
基于深度学习的长RNA二级结构预测的分治法：专注于假结识别	Omnes, L.	PDF	N/A	A divide-and-conquer approach based on deep learning for long RNA secondary structure prediction: focus on pseudoknots identification
Nerpa 2：将生物合成基因簇与非核糖体肽结构相链接	Olkhovskii, I.	PDF	N/A	Nerpa 2: linking biosynthetic gene clusters tononribosomal peptide structures
盖亚：一种用于微生物蛋白质的上下文感知序列搜索与发现工具	Jha, N.	PDF	N/A	Gaia: A Context-Aware Sequence Search and Discovery Tool for Microbial Proteins
通过长读长测序在细胞类型分辨率下进行表观遗传衰老特征分析	Eames, A.	PDF	N/A	Profiling Epigenetic Aging at Cell-Type Resolution Through Long-Read Sequencing
蛋白质语言可视化工具：语言模型时代的序列相似性网络	Herrera, J. E.	PDF	N/A	The Protein Language Visualizer: Sequence Similarity Networks for the Era of Language Models
伴侣蛋白TRiC在哺乳动物精子鞭毛中局部翻译的蛋白质折叠过程中，起到连接径向辐条的作用。	Cong, Y.	PDF	N/A	Chaperonin TRiC bridges radial spokes for folding proteins locally translated in mammalian sperm flagella
固醇裂解活化蛋白识别固醇的分子决定因素	Khiewdee, C.	PDF	N/A	Molecular determinant of sterol recognition by sterol cleavage activatory protein
HIF2α负调控MYCN蛋白水平，并促进神经母细胞瘤中的低风险去甲肾上腺素表型。	Yuan, J.	PDF	N/A	HIF2α negatively regulates MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastoma.
基于三嗪的水凝胶的设计与合成，用于联合靶向多柔比星递送和PI3K抑制	Mandal, S.	PDF	N/A	Design and synthesis of triazine-based hydrogel for combined targeted doxorubicin delivery and PI3Kinhibition
针对实验性腹膜损伤的STING靶向治疗：腹膜透析疗法的新方法	Marchant, V.	PDF	N/A	Targeting STING in experimental peritoneal damage: a novel approach in peritoneal dialysis therapy
设计改变GPCR G蛋白亚型选择性的变构调节剂	Moore, M. N.	PDF	N/A	Design of allosteric modulators that change GPCR G protein subtype selectivity
设计改变GPCR G蛋白亚型选择性的变构调节剂	Moore, M. N.	PDF	N/A	Design of allosteric modulators that change GPCR G protein subtype selectivity
西方饮食对田鼠身体组成、运动表现及血液生化特征的影响	HSEIKY, A.	PDF	N/A	Effect of Western diet on body composition, locomotor performance and blood biochemical profile in the bank vole
蚜虫效应蛋白通过招募防御蛋白到处理小体来抑制植物免疫	Liu, Q.	PDF	N/A	Aphid effectors suppress plant immunity via recruiting defence proteins to processing bodies
体外血管化复合异体移植物的预处理：范围综述	Baker, C. E.	PDF	N/A	Pre-treatments of Ex vivo Vascularized Composite Allografts: A Scoping Review
深度核逆向：快速且精准的分子相互作用预测，助力药物设计	Myers, S. A.	PDF	N/A	Deep Kernel Inversion: Rapid and Accurate Molecular Interaction Prediction for Drug Design
罕见病和常见病的基本模型中人类疾病机制的表示学习	Ravandi, B.	PDF	N/A	Representation Learning of Human Disease Mechanisms for a Foundation Model in Rare and Common Diseases
Ca2+和G蛋白对Cav2.2 N型Ca2+通道的复杂调控	Thomas, J.	PDF	N/A	Complex regulation of Cav2.2 N-type Ca2+ channels by Ca2+ and G-proteins
布洛卡区负责言语产生，受肺功能调节。	Siyu, C.	PDF	N/A	Broca's area responsible for speech production is regulated by lung functions
多巴胺能亚类神经元中显著不同的神经递质释放策略	Dorrego-Rivas, A.	PDF	N/A	Strikingly different neurotransmitter release strategies in dopaminergic subclasses
酒精戒断以一种依赖于中间神经元和性别特异性的方式改变了前外侧皮质区的抑制性环境	Quadir, S. G.	PDF	N/A	Alcohol Withdrawal Alters the Inhibitory Landscape of the Prelimbic Cortex in an Interneuron- and Sex-specific Manner
在感觉学习过程中，对生长抑素中间神经元进行长期、亚型特异性的调控	Zhu, M.	PDF	N/A	Long-lasting, subtype-specific regulation of somatostatin interneurons during sensory learning
在脆性X综合征小鼠模型中前肢抓取学习缺陷	Young, L. F.	PDF	N/A	Deficits in forelimb reach learning in a mouse model of Fragile X syndrome
慢性尼古丁暴露下健康与条件性Presenilin-1/2敲除痴呆模型小鼠的代谢差异	Si, Y.	PDF	N/A	Metabolic Divergence Between Healthy and Conditional Presenilin-1/2 knockout Dementia Model Mice under Chronic Nicotine exposure
超越表象：通过深度学习预测脑电图以揭示脑活动深层次的奥秘	Semenkov, I.	PDF	N/A	Beyond the Surface: Revealing the Depths of Brain Activity by Predicting fMRI from EEG with Deep Learning
猕猴在扫视期间出现的二维视觉错位现象	Baumann, M. P.	PDF	N/A	Two-dimensional perisaccadic visual mislocalization in rhesus macaque monkeys
磷脂酰丝氨酸翻转酶1（PLSCR1）调控干扰素-λ受体1（IFN-lambdaR1）及干扰素-λ信号在甲型流感病毒（IAV）感染中的作用	Yang, A. X.	PDF	N/A	Phospholipid Scramblase 1 (PLSCR1) Regulates Interferon-Lambda Receptor 1 (IFN-lambdaR1) and IFN-lambda Signaling in Influenza A Virus (IAV) Infection
在具有口腔风险习惯的斯里兰卡男性患者群体的口腔鳞状细胞癌（OSCC）组织中，微生物失调现象明显：重新审视以确认	Perera, M. L.	PDF	N/A	Microbial dysbiosis is evident in oral squamous cell carcinoma (OSCC) tissues of a group of Sri Lankan male patients with oral risk habits: Revisiting for confirming
检测到中大西洋赤道圣彼得和圣保罗群岛海鸟环境粪便样本中的德尔塔冠状病毒	Gomes, F.	PDF	N/A	Detection of Deltacoronavirus in Environmental Fecal Samples from Seabirds in the Saint Peter and Saint Paul Archipelago, central equatorial Atlantic Ocean
Piezo1 通过平衡膜张力和皮质肌动蛋白收缩力，以稳定细胞间连接并维持上皮屏障的完整性。	Javed, A.	PDF	N/A	Piezo1 balances membrane tension and cortical contractility to stabilize intercellular junctions and maintain epithelial barrier integrity
在浑浊和污染的水质条件下，石珊瑚（Orbicella faveolata）的加速生长	Lizcano-Sandoval, L.	PDF	N/A	Accelerated growth of the scleractinian coral Orbicella faveolata under turbid and polluted water conditions
古代气候变化和选择放松塑造了北美洞穴鱼类的洞穴定殖	Hart, P.	PDF	N/A	Ancient climate changes and relaxed selection shape cave colonisation in North American cavefishes
利用支系特异性靶向富集诱饵集构建黄芪（豆科）的强健骨干	Buono, D.	PDF	N/A	Building a robust backbone for Astragalus (Fabaceae) using a clade-specific target enrichment bait set
揭示性别、个体表型变异与觅食策略中的社会信号之间的复杂关系	Leitao, A. V.	PDF	N/A	Revealing complex relationships between sex, individuals' phenotype variation and social signalling in foraging strategies
利用磁性分选控制人干细胞衍生的胰岛组成	Kelley, A. B.	PDF	N/A	Controlling human stem cell-derived islet composition using magnetic sorting
交配和蜕皮激素信号传导改变了雌性果蝇肠道中的生长、代谢和消化效率	Kandelouei, T. N.	PDF	N/A	Mating and ecdysone signaling modify growth, metabolism, and digestive efficiency in the female Drosophila gut
人类骨骼肌在反复抗阻训练后，不仅表现出可逆的蛋白质组学特征，还保留了蛋白质组学记忆。	Hulmi, J. J.	PDF	N/A	Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training
地钱（Marchantia polymorpha）亚种ruderalis的群体基因组学研究揭示了气候适应的证据	Dolan, L.	PDF	N/A	Population genomics of Marchantia polymorpha subspecies ruderalis reveals evidence of climate adaptation
牛粪肥料中含有什么？深入了解其对植物防御系统支持的潜力	Wilson, K.	PDF	N/A	What's in Cow Dung Manure? Insights into Its Potential for Supporting Plant Defense System
映射对象空间维度：从时间动态中获得的新见解	Kidder, A.	PDF	N/A	Mapping object space dimensions: new insights from temporal dynamics
扣带回和纹状体中枢与早期技能学习有关。	Sugata, H.	PDF	N/A	Cingulate and striatal hubs are linked to early skill learning
定义不同RNA货物排序到细胞外囊泡中的参数	Batish, M.	PDF	N/A	Defining the parameters for sorting of different RNA cargo into Extracellular vesicles
网格蛋白通过共同维持高尔基体的结构-功能关系来支持细胞外基质的分泌。	Stevenson, N.	PDF	N/A	Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship
优化PSC培养以生成神经类器官	Sutcliffe, M. A.	PDF	N/A	Optimizing PSC culture for generating neural organoids
组织环境驱动胎儿膜和绒毛膜绒毛中滋养层分化的区域差异	Yang, L.	PDF	N/A	Tissue Context Drives Regional Differences in Trophoblast Differentiation in Fetal Membranes and Chorionic Villi
象海豹在冰期后对南大洋的重新占领是从多个冰期避难所发生的。	Berg, A.	PDF	N/A	Postglacial recolonization of the Southern Ocean by elephant seals occurred from multiple glacial refugia
真菌来源的tRNAs在兰花线粒体中表达并被氨酰化。	Warren, J. M.	PDF	N/A	Fungal-derived tRNAs are expressed and aminoacylated in orchid mitochondria
远程控制性染色体的减数分裂驱动	Greenberg, N. L.	PDF	N/A	Remote-control meiotic drive of sex chromosomes
一种多模态体内组合遗传筛选平台揭示了肝脏功能调控因子	Saunders, R. A.	PDF	N/A	A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
一种多模态体内组合遗传筛选平台揭示了肝脏功能调控因子	Saunders, R. A.	PDF	N/A	A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
肿瘤-基质相互作用下游的信号传导调控粘液性结直肠腺癌的顶基极性	Pasquier, N.	PDF	N/A	Signaling downstream of tumor-stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity
组蛋白H2B变体的异常表达重塑染色质结构并改变致癌基因表达程序	Saintilnord, W. N.	PDF	N/A	Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs
组蛋白H2B变体的异常表达会重塑染色质结构，并改变致癌基因表达程序。	Saintilnord, W. N.	PDF	N/A	Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs
人口密集的细胞和细胞器分割的多平面深度学习管道	Fulton, S.	PDF	N/A	Densely Populated Cell and Organelles Segmentation With Multi-Plane Deep Learning Pipeline
人口密集的细胞和细胞器分割的多平面深度学习管道	Fulton, S.	PDF	N/A	Densely Populated Cell and Organelles Segmentation With Multi-Plane Deep Learning Pipeline
一个用于去噪单细胞RNA测序数据的深度神经网络	Sharifitabar, M.	PDF	N/A	A deep neural network to de-noise single-cell RNAsequencing data
胶质瘤患者的临床和分子特征：miR-21在组织和血清中的表达作为预后生物标志物	Laghari, A. A.	PDF	N/A	Clinical and Molecular Characterization of Glioma Patients: miR-21 Expression as a Prognostic Biomarker in Tissue and Serum
探索拟杆菌属物种在抑郁症进展中的假定作用：基于宏基因组分析的见解	Li, Z.	PDF	N/A	Exploring the Hypothetical Role of Bacteroides Species in Depression Progression: Insights from Metagenomic Analysis
验证弱磁场对涡虫中超氧化物影响的自由基对机制预测	Rishabh,	PDF	N/A	Verification of radical pair mechanism predictions for weak magnetic field effects on superoxide in planarians
基于Mora-ERP的RNN-Transformer用于解码静默日语演讲期间的单次脑电图	Yamazaki, T.	PDF	N/A	Mora-ERP-based RNN-Transformer for decoding single-trial EEGs during silent Japanese speeches
社交触摸的平衡稳定益处：个体年龄及伴侣相对身体特征的影响	Johannsen, L.	PDF	N/A	The balance stabilising benefit of social touch: influence of an individual's age and the partner's relative body characteristics
严重创伤性脑损伤会暂时影响脑血流、内皮细胞表型和纤毛。	Gupta, A.	PDF	N/A	Severe traumatic brain injury temporally affects cerebral blood flow, endothelial cell phenotype, and cilia
乳酸通过靶向GluN2B亚基C端域中的半胱氨酸的细胞内氧化还原机制，增强NMDA受体电流：对突触可塑性的影响	Fiumelli, H.	PDF	N/A	Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting cysteines in the C-terminal domain of GluN2B subunits: implications for synaptic plasticity
全转录组钴氯化物诱导的低氧应答长非编码RNA的鉴定及其受细胞质mRNA加帽酶调控的研究	Ghosh, P.	PDF	N/A	Identification of transcriptome-wide cobalt chloride-induced hypoxia-responsive long noncoding RNAs regulated by cytoplasmic mRNA capping enzyme
曲霉属的转录因子BrlA被用于细胞壁应激的非分生孢子形成反应中。	Edwards, H.	PDF	N/A	Aspergillus nidulans Transcription Factor BrlA is Utilized in a Conidiation-Independent Response to Cell-Wall Stress
桥粒斑蛋白是一种桥粒机械感受器	Dong, Y.	PDF	N/A	Desmoplakin is a desmosomal mechanosensor
静息的神经干细胞会短暂地转变为“神经元”以协调重新激活。	Gherghina, L.-Y.	PDF	N/A	Quiescent neural stem cells transiently become 'neurons' to coordinate reactivation
多年干旱增强了正负功能多样性对树木生长响应的影响	Serrano-Leon, H.	PDF	N/A	Multi-year drought strengthens positive and negative functional diversity effects on tree growth response
ScTree：可扩展且稳健的流行病学和基因组数据机械整合方法，用于传播树推断	Waddel, H.	PDF	N/A	ScTree: Scalable and robust mechanistic integration of epidemiological and genomic data for transmission tree inference
甜菜根蛆（Tetanops myopaeformis）转录组样本统计数据，涉及其对甜菜（Beta vulgaris ssp. vulgaris）的易感性和抗性反应	Acharya, S.	PDF	N/A	The sugar beet root maggot, Tetanops myopaeformis transcriptome sample statistics in relation to it experiencing susceptible and resistant reactions with sugar beet, Beta vulgaris ssp. vulgaris
不同跑步速度下跑步鞋堆叠高度对跑步姿势和稳定性的影响	Kettner, C.	PDF	N/A	The effects of running shoe stack height on running style and stability during level running at different running speeds
原位整合多孔聚乙烯纳米膜与伤口渗出液以实现无痕愈合	Yuan, S.	PDF	N/A	In Situ Integration of Porous Polyethylene Nanomembrane with Wound Exudates for Scarless Healing
通过投影到形态学相关曲线上来识别空间变异基因	Nicol, P. B.	PDF	N/A	Identifying spatially variable genes by projecting to morphologically relevant curves
解析心肌梗死后修复性心肌成纤维细胞的分子激活机制	Hernandez, S. C.	PDF	N/A	Unravelling the molecular activation of the reparative cardiac fibroblasts after myocardial infarction
解析心肌梗死后修复性心脏成纤维细胞的分子激活机制	Hernandez, S. C.	PDF	N/A	Unravelling the molecular activation of the reparative cardiac fibroblasts after myocardial infarction
从扇形蠕虫中表征和工程化了一种蓝色敏感、Gi/o偏向且双稳态的纤毛视蛋白	Fukuzawa, S.	PDF	N/A	Characterization and engineering of a blue-sensitive, Gi/o-biased, and bistable ciliary opsin from a fan worm
从头鉴定AlphaFold2模型中冷冻电镜断层扫描图的蛋白质结构域	Lu, Y.	PDF	N/A	De novo identification of protein domains in cryo-electron tomography maps from AlphaFold2 models
通过机械反馈在菱脑神经孔形态发生中自我组织的细胞模式	Perez-Verdugo, F.	PDF	N/A	Self-organized cell patterning via mechanical feedback in hindbrain neuropore morphogenesis
Vγ9Vδ2TCR T细胞的敏感性是在早期癌变过程中通过单次突变后刻印下来的。	Cleven, A.	PDF	N/A	Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis
在自发慢性结肠炎的温尼小鼠模型中，炎症进展与肌萎缩的并行研究	Sharma, S.	PDF	N/A	Advancements in Inflammation Parallels Myopenia in Winnie Mice Model of Spontaneous Chronic Colitis
纵向血液微采样和蛋白质组监测有助于在实验性1型糖尿病中及时干预	Parajuli, A.	PDF	N/A	Longitudinal blood microsampling and proteome monitoring facilitate timely intervention in experimental type 1 diabetes
实体瘤中介导巨噬细胞化学保护性生态位的空间组织：一项数学分析	DANGELSER, W.	PDF	N/A	Spatial organization of mediated-macrophage chemoprotective niches in solid tumors: A mathematical analysis
在印度-缅甸生物多样性热点地区，形态相似的古热带螽斯科（Tettigoniidae）昆虫Mecopoda属的鸣声形态之间存在鸣声多样性。	Ghosh, A.	PDF	N/A	Syntopic call diversity among morphologically similar calling morphs ofthe paleotropical katydid of genus Mecopoda (Tettigoniidae) from an Indo-Burma biodiversity hotspot.
期望违背作为一种有效的替代复杂心理化的新型沟通方式	Buidze, T.	PDF	N/A	Expectation Violations as an Effective Alternative to Complex Mentalizing in Novel Communication
在线转向控制中的视觉惯性和视觉反馈	Liu, J.-Y.	PDF	N/A	Visuoinertial and visual feedback in online steering control
抗体竞争对B细胞受体激活的调节	He, Y.	PDF	N/A	Modulation of B cell receptor activation by antibody competition
PI3Kδ活性丧失通过损害胸腺外Treg分化驱动自身免疫性结肠炎	Lim, E. L.	PDF	N/A	Loss of PI3Kδ activity drives autoimmune colitis by impairing extrathymic Treg differentiation
卡波西肉瘤相关疱疹病毒解旋酶复合物成分ORF29的特性分析	Iwaisako, Y.	PDF	N/A	Characterization of the Kaposi's sarcoma-associated herpesvirus terminase complex component ORF29
从高保护到致命效果：使用不同白色念珠菌胞外囊泡进行侵袭性念珠菌病免疫接种的多样结果	Martinez-Lopez, R.	PDF	N/A	From high protection to lethal effect: diverse outcomes of immunization against invasive candidiasis with different Candida albicans extracellular vesicles
谷氨酸-赖氨酸（EK）丰富的RabD2基序通过自相互作用并调控通过多泡体途径的致病性，在溶组织内阿米巴中发挥作用。	Navyaka, P.	PDF	N/A	Glutamic acid-lysine (EK) rich motif of RabD2 self-associates and regulates pathogenesis through multivesicular bodies pathway in E. histolytica
在马基因组中搜索Jouvence SnoRNA	Peffers, M. J.	PDF	N/A	Searching for Jouvence SnoRNA in the Horse Genome
植物来源细胞外囊泡的真实参考标志物及其系统发育保守程度的综合概述	Rodriguez de Lope, M. M.	PDF	N/A	A compendium of bona fide reference markers of plant-derived extracellular vesicles and their degree of phylogenetic conservation
实时成像：抗疟药物对感染恶性疟原虫的红细胞的影响	Wallner, J. S.	PDF	N/A	Real-Time Imaging of Antimalarial Drug Effects on Plasmodium falciparum-Infected Red Blood Cells
AI引导的体素提取和体积电镜识别出入侵位点为线粒体接触点	Padman, B. S.	PDF	N/A	AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact
转录调控逻辑协调淋巴细胞和髓细胞命运决定	Godini, R.	PDF	N/A	Transcriptional Regulatory Logic Orchestrating Lymphoid and Myeloid Cell Fate Decisions
肌萎缩侧索硬化症（ALS）和额颞叶痴呆（FTD）相关蛋白Annexin A11和CHMP2B在膜修复过程中依次发挥作用	Heffner, C. M.	PDF	N/A	The ALS- and FTD-associated proteins Annexin A11 and CHMP2B act sequentially in membrane repair
昆虫肠道中的免疫启动：通过超微结构和转录组变化揭示的动态反应	Baur, M.	PDF	N/A	Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes
真菌中附着染色体的水平转移——遗传物质交换的调控过程？	Habig, M.	PDF	N/A	Horizontal transfer of accessory chromosomes in fungi - a regulated process for exchange of genetic material?
基因型与环境相互作用塑造泛素-蛋白酶体系统活性	Avery, R. R.	PDF	N/A	Genotype-by-environment interactions shape ubiquitin-proteasome system activity
绿意T2T：散叶莴苣（Lactuca sativa var. crispa）端粒到端粒基因组组装与注释的升级版	Zhang, B.	PDF	N/A	Green Elegance T2T: An upgraded telomere-to-telomere genome assembly and annotation of looseleaf lettuce (Lactuca sativa var. crispa)
风洞研究：海豚母子配对中的跟风力	Weihs, D.	PDF	N/A	Wind Tunnel Study of the Forces Due to Drafting in Dolphin Mother-Calf pairs
ConvCGP：一种卷积神经网络，用于从压缩的全基因组多态性预测水稻性状的基因型值	Islam, T.	PDF	N/A	ConvCGP: A Convolutional Neural Network to Predict Genotypic Values of Rice Traits from Compressed Genome-Wide Polymorphisms
探索HLA在通过T细胞受体预测感染状态中的作用	Ding, F.	PDF	N/A	Exploration of the Roles of HLAs When Predicting Infection Status by T Cell Receptors
从网络拓扑中揭示生化反应系统的分岔行为	Huang, Y.-J.	PDF	N/A	Uncovering Bifurcation Behaviors of Biochemical Reaction Systems from Network Topology
激光闪熔冷冻电镜样品以克服择优取向	Straub, M. S.	PDF	N/A	Laser Flash Melting Cryo-EM Samples to Overcome Preferred Orientation
三步前进：PTPN5的三种意外结构	Guerrero, L.	PDF	N/A	Three STEPs forward: A trio of unexpected structures of PTPN5
朝着鲁棒机器嗅觉迈进：去偏的GC-MS数据增强了从尿液挥发性物质中诊断前列腺癌的能力	Rotteveel, A.	PDF	N/A	Towards robust machine olfaction: debiasing GC-MS data enhances prostate cancer diagnosis from urine volatiles
通过正电子发射断层扫描技术实现肿瘤微环境中pH变化的非侵入性可视化	Brueck, J.	PDF	N/A	Non-invasive visualization of pH changes within the tumor-micro-environment by positron emission tomography
在研究心肌生物电活动变化中，使用深度学习算法进行微电极阵列电图的分割	Kotikhina, E.	PDF	N/A	Use of deep learning algorithms for segmentation of microelectrode arrays electrograms in the study of changes in myocardial bioelectrical activity
一种复合亚单位疫苗在鼠足垫模型中对溃疡分枝杆菌感染提供了完全的保护，从而预防了布如里溃疡病。	Boakye-Appiah, J. K.	PDF	N/A	A composite subunit vaccine confers full protection against Buruli ulcer disease in the mouse footpad model of Mycobacterium ulcerans infection
通过多组学揭示骨骼肌中内源性组织细胞外囊泡的功能异质性	Wang, Y.	PDF	N/A	Unveiling the functional heterogeneity of endogenous tissue extracellular vesicles in skeletal muscle through multi-omics
单细胞荧光成像揭示了衰老生物标志物的异质性，并鉴定出雷帕霉素响应的亚群	Seshadri, V.	PDF	N/A	Single-cell fluorescence imaging reveals heterogeneity in senescence biomarkers and identifies rapamycin-responsive sub-populations
X染色体上的ARHGAP36基因位点的缺失与玳瑁猫和三花猫的橙色毛色有关。	Toh, H.	PDF	N/A	A deletion at the X-linked ARHGAP36 gene locus is associated with the orange coloration of tortoiseshell and calico cats
Hydractinia symbiolongicarpus中单一Helitron亚家族的扩展表明刺胞动物染色体扩展的共享机制	Kon, T.	PDF	N/A	Expansion of a single Helitron subfamily in Hydractinia symbiolongicarpus suggests a shared mechanism of cnidarian chromosomal extension
人类存在与活动类型对城市欧亚红松鼠创新问题解决能力的影响。	Chow, P. K. Y.	PDF	N/A	The Effect of Human Presence and Activity Type on Innovative Problem-Solving of Urban Eurasian Red Squirrels.
通过氧化还原途径对Sungouiella intermedia中乳糖和半乳糖代谢的模型驱动阐释，用于细胞工厂应用	Peri, K. V.	PDF	N/A	Model-Driven Elucidation of Lactose and Galactose Metabolism via Oxidoreductive Pathway in Sungouiella intermedia for Cell Factory Applications
保守基团代谢流组学	Fleming, R. M.	PDF	N/A	Conserved moiety fluxomics
Trikafta通过加强特定的磷酸化依赖性域间相互作用，挽救了F508del-CFTR。	Wang, G.	PDF	N/A	Trikafta rescues F508del-CFTR by tightening specific phosphorylation-dependent interdomain interactions
CellBinDB：一个大规模多模态注释数据集，用于细胞分割，并包含通用模型的基准测试	Shi, C.	PDF	N/A	CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models
共享节奏到共享愿景：同步行进提升感知决策中的从众行为	Biswas, M.	PDF	N/A	Shared Rhythm to Shared Vision: Synchronous Marching increases Conformity on Perceptual Decision making
用于快速重定位波形蛋白中间丝的光遗传学和化学遗传学工具	Pasolli, M.	PDF	N/A	Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments
西非几内亚比绍不同土地利用类型下的两栖动物和爬行动物数据集	dos Reis-Silva, F.	PDF	N/A	Amphibian and reptile dataset across different land-use types in Guinea-Bissau, West Africa
致癌长链非编码RNA NEAT1在软与硬基质上的机械感知作用及其对胶质母细胞瘤进展的影响	Ghosh, A.	PDF	N/A	Mechano-sensing role of oncogenic lncRNA NEAT1 on soft vs. stiff substrates and its implications for glioblastoma progression
BAZ1A，一种模拟开关（ISWI）蛋白，与E2F1相互作用并促进其招募，以激活E2F转录程序。	Prajapati, B.	PDF	N/A	BAZ1A, an Imitation Switch (ISWI) protein, interacts and facilitates the recruitment of E2F1 to activate the E2F transcription program
年龄相关的TREM1/2表达巨噬细胞的调控促进黑色素瘤进展和转移	Scotegagna, M.	PDF	N/A	Age-associated modulation of TREM1/2- expressing macrophages promotes melanoma progression and metastasis
内在和外在机制改变EPM1癫痫中的神经细胞命运特化	Forero, A.	PDF	N/A	Intrinsic and extrinsic mechanisms alter neural cell fate specification in EPM1 Epilepsy
轴突转录组揭示了PLK1的上调作为FUSP525L脊髓运动神经元中应对DNA损伤增加的保护机制	Zimyanin, V.	PDF	N/A	Axonal transcriptome reveals upregulation of PLK1 as a protective mechanism in response to increased DNA damage in FUSP525L spinal motor neurons
刺豚鼠和BMP信号传导驱动斑马鱼中黑色素细胞向白色素细胞的自然发生的命运转换	Huang, D.	PDF	N/A	Agouti and BMP signaling drive a naturally occurring fate conversion of melanophores to leucophores in zebrafish
多面体：高分辨率表位条形码用于体内空间命运图谱绘制	Postrach, D.	PDF	N/A	Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping
在管状器官形成过程中顶端细胞外基质的组织	Woodward, J. L.	PDF	N/A	Organization of the apical extracellular matrix during tubular organ formation
Ox-LDL在人内皮细胞中诱导出一种富含冠状动脉疾病风险的非炎症反应	Jiang, J.	PDF	N/A	Ox-LDL induces a non-inflammatory response enriched for coronary artery disease risk in human endothelial cells
Beta-DIA：整合基于学习的和基于功能的特征评分，以优化单次diaPASEF质谱数据的蛋白质组学分析	Song, J.	PDF	N/A	Beta-DIA: Integrating learning-based and function-based feature scores to optimize the proteome profiling of single-shot diaPASEF mass spectrometry data
XAI-MRI：一种基于磁共振成像的3D脑肿瘤分割的集成双模态方法	Farhan, A. S.	PDF	N/A	XAI-MRI: An Ensemble Dual-Modality Approach for 3D Brain Tumor Segmentation Using Magnetic Resonance Imaging
通过靶向伽马射线递送和卷积神经网络减轻化疗副作用：迈向精准肿瘤学的一步	Siddiqui, S.	PDF	N/A	Mitigating Chemotherapy Side Effects through Targeted Gamma-Ray Delivery and Convolutional Neural Networks: A Step Toward Precision Oncology
破伤风类毒素通过靶向肿瘤唾液酸和增强细胞毒性CD4+ T细胞对胰腺癌的反应，利用双面抗癌机制	Gupta, K.	PDF	N/A	Tetanus Toxoid Utilizes Dual-Faceted Anticancer Mechanism Through Targeting Tumoral Sialic Acids and Enhancing Cytotoxic CD4+ T cell Responses Against Pancreatic Cancer
异质性内分泌细胞组成定义了人类胰岛的功能表型	Evans-Molina, C.	PDF	N/A	Heterogeneous endocrine cell composition defines human islet functional phenotypes
海岸红杉（Sequoia sempervirens）在整个分布范围内的非整倍体发生情况	Nikolaeva, A. S.	PDF	N/A	Occurrence of Aneuploidy Across the Range of Coast Redwood (Sequoia sempervirens)
短期水分胁迫对大麦花药成熟过程中的形态和分子效应	Lange, R. J.	PDF	N/A	Morphological and molecular effects of short-term water deficiency in barley stamen maturation
慢伽马和快伽马振荡在猕猴初级视觉皮层中显示出与不同高频带的相位-幅度耦合。	Prabhu, P.	PDF	N/A	Slow and fast gamma oscillations show phase-amplitude coupling with distinct high-frequency bands in macaque primary visual cortex
SIGNAL：用于语言的语义和推断语法神经分析的数据集	Komissarenko, A.	PDF	N/A	SIGNAL: Dataset for Semantic and Inferred Grammar Neurological Analysis of Language
小脑和基底神经节的关联-边缘区域与感觉运动区域在显性情绪处理与隐性情绪处理中的不同参与度	Ceravolo, L.	PDF	N/A	Differential Engagement of Associative-Limbic and Sensorimotor Regions of the Cerebellum and Basal Ganglia in Explicit vs. Implicit Emotional Processing
在有障碍物的情况下行走时，注视以抓住物体	Voudouris, D.	PDF	N/A	Gaze when walking to grasp an object in the presence of obstacles
模拟两个输入具有不同共性的短期记忆的神经网络	Raman, E.	PDF	N/A	Neural networks simulating short-term memory of two inputs with varying commonality
异性配对改变了雄性草原田鼠岛叶皮层中社会互动诱导的GCaMP和多巴胺活性	Vitale, E. M.	PDF	N/A	Opposite-sex pairing alters social interaction-induced GCaMP and dopamine activity in the insular cortex of male prairie voles
果蝇黑腹果蝇（Drosophila melanogaster）湿度感受器在湿度依赖性下的结构适应	Enjin, A.	PDF	N/A	Humidity-dependent structural adaptations of Drosophila melanogaster hygrosensilla
非空间网格状神经编码的发展预测了推理与智能	Qu, Y.	PDF	N/A	Development of Non-Spatial Grid-Like Neural Codes Predicts Inference and Intelligence
星形胶质细胞特异性分泌组分析揭示其与神经疾病的关联	Liu, J.	PDF	N/A	Astrocyte-specific secretome profiling reveals its correlation with neurological disorders
瞳孔测量与全脑c-Fos成像揭示了小鼠情绪传染网络中的多模态镜像机制	Caldarelli, M.	PDF	N/A	Pupillometry and Whole-Brain c-Fos Mapping Uncover Multimodal Mirror Mechanisms in Emotional Contagion Networks of Mice
通过脑电图探索序数情感表征的神经基础和有效性	Chen, X.	PDF	N/A	Exploring the Neural Basis and Validity of Ordinal Emotion Representation through EEG
人类大脑皮层中时间预期的神经特征反映了事件概率密度	Grabenhorst, M.	PDF	N/A	Neural signatures of temporal anticipation in human cortex represent event probability density
在人类视网膜中以高空间和时间分辨率测量闪烁诱导的血管舒张。	Senee, P.	PDF	N/A	Measuring flicker induced vasodilation at a high spatial and temporal resolution in the human retina.
兴奋性神经元中增强子上EGR1结合的升高与神经元亚型特异性的表观遗传调控相关	Yin, L.	PDF	N/A	Elevated EGR1 Binding at Enhancers in Excitatory Neurons Correlates with Neuronal Subtype-Specific Epigenetic Regulation
TRAIT：T细胞受体-抗原相互作用综合数据库	Wei, M.	PDF	N/A	TRAIT: A Comprehensive Database for T-cell Receptor-Antigen Interactions
一种免疫机械检查点PYK2调控单核细胞向巨噬细胞的分化在胰腺癌中	Xie, W.	PDF	N/A	An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer
通过T细胞中抗原的CAR内吞作用实现靶向蛋白质降解	Peng, M.	PDF	N/A	Targeted protein degradation via CAR endocytosis of antigen in T cells
角质细胞暴露于急性和慢性蓝光下的阶段特异性表型和转录变化	Tonolli, P. N.	PDF	N/A	Stage-specific phenotypic and transcriptional alterations in keratinocytes exposed to acute and chronic blue light
PFAS化合物PFOA和Gen X对海胆胚胎具有致畸性。	Lion, A. T.	PDF	N/A	PFAS Compounds PFOA and Gen X are Teratogenic to Sea Urchin Embryos
在妊娠初期对人类心脏图谱进行多模态细化	De Bono, C.	PDF	N/A	Multi-modal refinement of the human heart atlas during the first gestational trimester
发育中的肠道中通过抑制性作用自组织形成的蠕动波图案	Kawamura, K.	PDF	N/A	Self-organized patterning of peristaltic waves by suppressive actions in a developing gut
每日暴露于1.7 GHz LTE电磁场对早期胎儿大脑发育的影响：使用人脑皮质类器官模型进行的研究	Park, G. Y.	PDF	N/A	Effect of the daily exposure of 1.7 GHz LTE electromagnetic field in early fetal brain development using a human brain organoid model of the cerebral cortex
人为噪音可能会通过阻碍蜜蜂介导的授粉过程，从而降低番茄的繁殖成功率。	Varga-Szilay, Z.	PDF	N/A	Anthropogenic noise can decrease tomato reproductive success by hindering bumblebee-mediated pollination
在六种多细胞真核生物模型中，基因年龄越大，多效性越强。	Martin, R. A.	PDF	N/A	Pleiotropy increases with gene age in six model multicellular eukaryotes
TIRE-seq：一种集成样品提取与转录组学工作流程，用于高通量扰动研究	O'Keeffe, P.	PDF	N/A	TIRE-seq: an Integrated Sample Extraction and Transcriptomics Workflow for High Throughput Perturbation Studies
CTCF耗竭在细胞分化过程中将增强子介导的基因激活与染色质枢纽形成解耦	Karpinska, M. A.	PDF	N/A	CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation during cellular differentiation
雌性鸣叫声引发Alston鸣鼠两性更强烈的鸣叫展示	Tripp, J. A.	PDF	N/A	Female song elicits increased vocal display effort in both sexes of Alston's singing mouse
寻找路径：果蝇幼虫的局部搜索行为	Kromp, J.	PDF	N/A	Finding a path: Local search behavior of Drosophila larvae
无菌条件下神经行为特征的评估：在同一只小鼠中进行多次纵向分析的方法。	Rutsch, A.	PDF	N/A	Assessment of neurobehavioural traits under axenic conditions: an approach for multiple longitudinal analyses in the same mouse.
SPO11依赖的双链断裂形成的重建	Zheng, Z.	PDF	N/A	Reconstitution of SPO11-dependent double-strand break formation
细菌泛素样蛋白的结构多样性和寡聚化	Gong, M.	PDF	N/A	Structural diversity and oligomerization of bacterial ubiquitin-like proteins
微生物物种树重建的系统评估	Weiner, S.	PDF	N/A	A systematic assessment of phylogenomic approaches for microbial species tree reconstruction
超越整合：SuperGLUE促进多模态数据分析的可解释训练框架	Liu, T.	PDF	N/A	Beyond Integration: SuperGLUE Facilitates Explainable Training Framework for Multi-modal Data Analysis
机器学习应用：预测含有非规范氨基酸的肽与HLA0201的结合亲和力	Jiang, S.	PDF	N/A	Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA0201
TaxSEA：一个用于快速解读差异丰度分析结果的R包。	Ryan, F. J.	PDF	N/A	TaxSEA: an R package for rapid interpretation of differential abundance analysis output.
红细胞的聚集与解聚：耗竭与桥接	Moreno, N.	PDF	N/A	Aggregation and disaggregation of red blood cells: depletion versus bridging
一种tau-紫杉醇竞争的地板场模型解释了紫杉醇稳定微管上的tau包膜动力学	Chevalier, C.	PDF	N/A	A floor-field model of tau-taxol competition explains tau envelope dynamics on taxol-stabilized microtubules
靶向黑色素瘤中依赖eIF4G1的翻译	Feng, Y.	PDF	N/A	Targeting eIF4G1-dependent translation in melanoma
Ezh2在正常小脑颗粒神经元发育和髓母细胞瘤中延迟分化基因的激活	Purzner, J.	PDF	N/A	Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma
描述转移性癌症迁移历史解空间的特征：MACH2	Roddur, M. S.	PDF	N/A	Characterizing the Solution Space of Migration Histories of Metastatic Cancers with MACH2
Rho GTPase信号传导介导了神经母细胞瘤肿瘤的侵袭性和分化	Gomez-Munoz, M. A.	PDF	N/A	Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors
超小颗粒纳米气泡水饮用通过改善抗氧化活性对慢性运动疲劳大鼠产生抗疲劳作用	Qi, J.	PDF	N/A	Ultra-small Particle Size Nanobubbles Water Drinking Exerts Antifatigue Effects in Chronic Exercise Fatigue Rats via Improving Antioxidative Activities
一种新发现的拟南芥蛋白，ABAP1相互作用蛋白10，介导了细胞周期与初级代谢之间的交叉对话	MONTESSORO, P.	PDF	N/A	A novel Arabidopsis thaliana protein, ABAP1 INTERACTING PROTEIN 10, mediates crosstalk between the cell cycle and primary metabolism
大麦对真菌细胞侵入的抗性和易感性涉及ROP信号与磷脂酰肌醇单磷酸之间的相互作用。	Weiss, L. S.	PDF	N/A	Barley resistance and susceptibility to fungal cell entry involve the interplay of ROP signaling with phosphatidylinositol-monophosphates
无抗生素全细胞生物催化发酵：表面展示PETase的工程大肠杆菌用于可持续塑料降解	Romero-Orejon, K.	PDF	N/A	Antibiotic-free whole-cell biocatalytic fermentation: Escherichia coli with surface-displayed PETases for sustainable plastic degradation
人类屏状核在多种认知任务中被激活	Huang, C. H. L.	PDF	N/A	The human claustrum activates across multiple cognitive tasks
语义整合需求调节大脑大规模网络交互	Nieberlein, L.	PDF	N/A	Semantic integration demands modulate large-scale network interactions in the brain
负载CSF1R拮抗剂的纳米颗粒可选择性耗竭小胶质细胞，并调节脊髓损伤中的炎症反应。	Yang, J.	PDF	N/A	Nanoparticles loaded with a CSF1R antagonist selectively depletes microglial cells and modulates inflammation in spinal cord injury
帕金森病中感觉运动皮层-丘脑下核回路的Beta爆发特征及其耦合关系	Yao, P.	PDF	N/A	Beta burst characteristics and coupling within the sensorimotor cortical-subthalamic nucleus circuit in Parkinson's disease
由Rab39调控的Atg9顺行运输介导的突触自噬的以Soma为中心的调控	Kilic, A.	PDF	N/A	Soma-centered control of synaptic autophagy by Rab39-regulated anterograde trafficking of Atg9
双特异性磷酸酶1（DUSP1）在调节由伯氏疏螺旋体脂蛋白调控的巨噬细胞炎症通路中的作用	Kumaresan, V.	PDF	N/A	Role of Dual Specificity Phosphatase 1 (DUSP1) in influencing inflammatory pathways in macrophages modulated by Borrelia burgdorferi lipoproteins
树突状细胞通过嵌合突触促进CAR T细胞在放射治疗后的肿瘤中的加速作用	Navarre, S.	PDF	N/A	Dendritic cells accelerate CAR T cells in irradiated tumors through chimeric synapses
在持续人为压力下，城市微生物群落向产生类胡萝卜素物种转变。	Sedova, V. V.	PDF	N/A	Urban microbial communities shift towards carotenoid-producing species under constant anthropogenic stress
多重PCR技术用于测量实验性尿路感染期间尿路致病性大肠杆菌的原位生长速率。	Paudel, S.	PDF	N/A	Multiplexed PCR to measure in situ growth rates of uropathogenic E. coli during experimental urinary tract infection.
Dickeya dadantii 3937 产生 P2D1 尾菌素：胁迫启动、基因表达与活性粒子浓度之间的时间关系	Sobolewska, M.	PDF	N/A	Production of P2D1 tailocins by Dickeya dadantii 3937: a temporal relationship between the stressor onset, gene expression, and the concentration of active particles
从人类鼻腔和皮肤分离出的两种新型棒状杆菌属物种的描述	Popowitch, E. B.	PDF	N/A	Description of two novel Corynebacterium species isolated from human nasal passages and skin
TcCARP3调节了与渗透调节、哺乳动物细胞感染以及人类病原体克鲁斯锥虫在锥蝽媒介中定殖相关的区室化cAMP信号。	Carlson, J.	PDF	N/A	TcCARP3 modulates compartmentalized cAMP signals involved in osmoregulation, infection of mammalian cells, and colonization of the triatomine vector in the human pathogen Trypanosoma cruzi
亚治疗浓度的抗生素在铜绿假单胞菌中诱导了前噬菌体驱动的超感染排斥和适应性代价	Bucher, M. J.	PDF	N/A	Sub-therapeutic Concentrations of Antibiotics Induce Prophage-driven Superinfection Exclusion and Fitness Cost in Pseudomonas aeruginosa
钙调神经磷酸酶抑制剂会抑制丙酮酸脱氢酶的活性，并导致近端小管细胞的代谢功能障碍，从而引发促纤维化表型。	Oda, Y.	PDF	N/A	Calcineurin inhibition deactivates pyruvate dehydrogenase and induces proximal tubule cell metabolic dysfunction, causing profibrotic phenotype
发育中的羽毛细胞类型的遗传特征及其复杂性的演化	Limber, C.	PDF	N/A	Genetic Characterization of the Cell Types of in Developing Feathers, and the Evolution of Feather Complexity
大肠杆菌中增加乙酸代谢的代谢权衡	Pentz, J. T.	PDF	N/A	Metabolic trade-offs in response to increased acetate metabolism in Escherichia coli
海蜘蛛的基因组证实了节肢动物中减少的后部体节共享的Hox集群模式。	Papadopoulos, N.	PDF	N/A	The genome of a sea spider corroborates a shared Hox cluster motif in arthropods with reduced posterior tagma
通过甲醛固定、冷冻保存和多重化技术增强单细胞ATAC测序，以实现灵活分析	Hohl, T.	PDF	N/A	Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysis
双功能伴侣蛋白中可切换的客户端特异性协调光捕获复合物的生物合成	Siegel, A. R.	PDF	N/A	Switchable client specificity in a dual functional chaperone coordinates light harvesting complex biogenesis
在分化细菌泛素化途径中蛋白质偶联的机制基础	Ye, Q.	PDF	N/A	Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway
可溶性细菌视紫红质的工程改造	Nikolaev, A.	PDF	N/A	Engineering of soluble bacteriorhodopsin
用于活细胞中灵敏且同时成像不同单个mRNA的RNA稳定化外壳蛋白	Kuffner, C. J.	PDF	N/A	RNA-Stabilized Coat Proteins for Sensitive and Simultaneous Imaging of Distinct Single mRNAs in Live Cells
使用行-列阵列在离体心室心肌的双轴测试期间进行三维组织应变测量	Navy, X.	PDF	N/A	Three-dimensional tissue strain measurement using a row-column array during biaxial testing of excised ventricular myocardium
Alphafold2 优化提升了大型从头设计蛋白质的可设计性	Frank, C. J.	PDF	N/A	Alphafold2 refinement improves designability of large de novo proteins
FocalSV：基于目标区域的结构变异组装与优化，利用单分子长读长测序数据	Luo, C.	PDF	N/A	FocalSV: target region-based structural variant assembly and refinement using single-molecule long read sequencing data
RobustCell：一种用于稳健转录组数据分析的模型攻击防御框架	Liu, T.	PDF	N/A	RobustCell: A Model Attack-Defense Framework for Robust Transcriptomic Data Analysis
相邻转录因子在DNA上结合的协同性的定量分析及其潜在功能相关性	Wang, X.	PDF	N/A	Quantification and potential functional relevanceof binding cooperativity of adjacent transcriptionfactors on DNA
甲硫氨酸代谢、DNA修复与胶质母细胞瘤中的治疗抵抗之间的相互联系	Korimerla, N.	PDF	N/A	Reciprocal links between methionine metabolism, DNA repair and therapy resistance in glioblastoma
使用mRNA-LNPs生成的CAR-NK细胞有效靶向CD19阳性原发性B-ALL细胞	Salehi-Shadkami, H.	PDF	N/A	Effective targeting of CD19 positive primary B-ALL cells using CAR-NK cells generated with mRNA-LNPs
肝肾有机阳离子转运体对西咪替丁-二甲双胍临床药代动力学相互作用的定量贡献	Ailabouni, A. S.	PDF	N/A	Quantitative contributions of hepatic and renal organic cation transporters to the clinical pharmacokinetic cimetidine-metformin interaction
自然历史藏品数据的动员可以提高生物多样性信息的质量和覆盖范围。	Blades, B.	PDF	N/A	Mobilisation of data from natural history collections can increase the quality and coverage of biodiversity information
下丘脑室旁核和视上核中的催产素神经元双向调节食物摄入。	Rea, J. J.	PDF	N/A	Oxytocin neurons in the paraventricular and supraoptic hypothalamic nuclei bidirectionally modulate food intake
皮层慢波的全球性和局部性	Alegre-Cortes, J.	PDF	N/A	Global and local nature of cortical slow waves
少突胶质细胞的区域异质性决定了兰维尔结在声音定位电路中单个轴突上的偏倚分布模式。	Egawa, R.	PDF	N/A	Regional heterogeneities of oligodendrocytes determine biased distribution pattern of Ranvier nodes along single axons in sound localization circuit
机器学习识别出与马脑炎病毒（EEV）、创伤性脑损伤（TBI）和有机磷神经毒剂（OPNA）引起神经疾病相关的基因	Yin, L.	PDF	N/A	Machine Learning Identifies Genes Linked to Neurological Disorders Induced by Equine Encephalitis viruses (EEV), Traumatic Brain Injuries (TBI), and Organophosphorus nerve agents (OPNA)
单剂量禽流感A(H5N1)谱系2.3.4.4b血凝素-基质-M纳米颗粒疫苗在非人灵长类动物中诱导中和反应	Patel, N.	PDF	N/A	Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M nanoparticle vaccine induces neutralizing responses in nonhuman primates
一种用于定量噬菌体病毒载体滴度和纯度的数字PCR检测方法。	Voorhees, P. J.	PDF	N/A	A Droplet Digital PCR Assay for Quantification of Bacteriophage Viral Vector Titer and Purity.
使用缺乏病毒致病基因的复制缺陷型鼠γ疱疹病毒进行疫苗接种可抑制野生型病毒感染	Mitra, D.	PDF	N/A	Vaccination with a Replication-Dead Murine Gammaherpesvirus Lacking Viral Pathogenesis Genes Inhibits WT Virus Infection
在随机组装过程中，微生物群落内部和之间的多样性驱动因素	Marrec, L.	PDF	N/A	Drivers of diversity within and between microbialcommunities during stochastic assembly
单一的高锌激活增强剂可以在秀丽隐杆线虫中控制两个头对头排列的基因	Liu, H.	PDF	N/A	A single high-zinc activation enhancer can control two genes oriented head-to-head in C. elegans
加压素V2受体的非活性结构揭示了Tolvaptan和Mambaquaretin毒素的不同拮抗剂结合模式	Fouillen, A.	PDF	N/A	Inactive structures of the vasopressin V2 receptor reveal distinct antagonist binding modes for Tolvaptan and Mambaquaretin toxin
慢性神经性疼痛状态对芬太尼及其他μ受体激动剂的辨别性刺激效应的影响	Burgess, G. E.	PDF	N/A	The effects of chronic neuropathic pain states on the discriminative stimulus effect of fentanyl and other MOR agonists
来自Amphitrite ornata的多功能催化血红蛋白：分离、分类鉴定、蛋白质提取、纯化及表征的操作流程	Husted, A. L.	PDF	N/A	The Multifunctional Catalytic Hemoglobin from Amphitrite ornata: Protocols on Isolation, Taxonomic Identification, Protein Extraction, Purification, and Characterization
生长依赖性调节Gin4激酶的机制	Diaz, F. M.	PDF	N/A	Mechanisms of growth-dependent regulation of the Gin4 kinase
淀粉质体对于地钱（Marchantia polymorpha）叶状体的完全向重力性反应是必需的。	Hashimoto-Sugimoto, M.	PDF	N/A	Amyloplasts are necessary for full gravitropism in thallus of Marchantia polymorpha
瞬时组蛋白去乙酰化酶抑制可诱导基因表达的细胞记忆及三维基因组折叠	Paldi, F.	PDF	N/A	Transient histone deacetylase inhibition induces cellular memory of gene expression and three-dimensional genome folding
# BioRxiv 2024-11-20 Papers

标题	作者	PDF链接	代码仓库	Title
JNK MAPK 调控化学耐药性、静止白血病细胞中的 IFN 刺激基因和细胞粘附	Lee, S.	PDF	N/A	JNK MAPK Regulates IFN-Stimulated Genes and Cell Adhesion in Chemoresistant, Quiescent Leukemic Cells
好妈妈：平原斑马中的依赖幼崽及其母亲比其他个体更能适应较长的旱季	Thel, L.	PDF	N/A	Good moms: dependent-young and their mothers cope better than others with longer dry season in plains zebras
SUMO激活酶亚单位SAE2对有丝分裂保真性中的SUMO蛋白偏向性有贡献。	Walker, A.	PDF	N/A	The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelity.
淋巴结成纤维细胞表型及由Podoplanin活性调控的免疫交叉对话	Makris, S.	PDF	N/A	Lymph node fibroblast phenotypes and immune crosstalk regulated by Podoplanin activity
使用dreamlet进行大规模单细胞转录组数据的高效差异表达分析	Hoffman, G. E.	PDF	N/A	Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet
N6-甲基腺苷（m6A）促进具有完整5'剪接位点基序的mRNA在细胞核中的保留	Lee, E. S.	PDF	N/A	N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5' Splice Site Motifs
农药诱导的褐飞虱再猖獗是通过影响一系列促进保幼激素生物合成和雌性生殖力的基因而介导的。	Gao, Y.	PDF	N/A	Pesticide-induced resurgence in brown planthopper is mediated by action on a suite of genes that promote juvenile hormone biosynthesis and female fecundity
APOBEC3活性促进肺癌中获得性耐药EGFR抑制剂期间耐药持久细胞的存活和进化	Garcia, N. M. G.	PDF	N/A	APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer
中介激酶抑制剂抑制唐氏综合征中过度活跃的干扰素信号传导	Cozzolino, K.	PDF	N/A	Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
在自然音乐聆听过程中映射多模态动态网络活动	Faber, S. E.	PDF	N/A	Mapping multi-modal dynamic network activity during naturalistic music listening
高置信度糖体膜蛋白清单揭示了锥虫中的过氧化物酶体蛋白PEX15	Krishna, C. K.	PDF	N/A	High confidence glycosomal membrane protein inventory unveils trypanosomal Peroxin PEX15
在运动执行和运动规划过程中，控制策略可以根据任务需求进行调整。	Orban de Xivry, J.-J.	PDF	N/A	A control policy can be adapted to task demands during both motor execution and motor planning
Oct4 与 Sox2 之间的新兴协同作用调控着早期小鼠胚胎中的多能性网络。	Hou, Y.	PDF	N/A	Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in early mouse embryos
评估不同突变发现方法之间的不一致体细胞突变，以最大限度减少假阴性耐药性发现	Lin, H.-F.	PDF	N/A	Evaluating discordant somatic calls across mutation discovery approaches to minimize false negative drug-resistant findings
基于电导的神经元模型中高去极化基线偏移的机制与意义	Kumar, A.	PDF	N/A	Mechanisms and implications of high depolarization baseline offsets in conductance-based neuronal models
共受体Tetraspanin12直接捕获Norrin以促进配体特异性的β-连环蛋白信号传导	Bruguera, E. S.	PDF	N/A	The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling
全球多样性与进化：巴拿马沙门氏菌——一种全球范围内引起胃肠道和侵袭性疾病但研究不足的血清型：一项基因组流行病学研究	Pulford, C. V.	PDF	N/A	Global diversity and evolution of Salmonella Panama, an understudied serovar causing gastrointestinal and invasive disease worldwide: a genomic epidemiology study
白血病的侵袭性受染色质重塑和核心调控因子表达变化所驱动。	Bonilla, G.	PDF	N/A	Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators
在视觉-正字法预测误差表征中指定精度，以更好地理解高效阅读	Fu, W.	PDF	N/A	Specifying precision in visual-orthographic prediction error representations for a better understanding of efficient reading
蜜蜂嗉囊中的细菌与花蜜和蜜蜂口腔中的细菌不相关。	Warren, M. L.	PDF	N/A	Bacteria in honeybee crops are decoupled from those in floral nectar and bee mouths
成年神经发生协调了嗅觉感知记忆的灵活性和稳定性	Sakelaris, B.	PDF	N/A	Adult Neurogenesis Reconciles Flexibility and Stability of Olfactory Perceptual Memory
性染色体的进化与物种形成的两个规则的单一理论	Lenormand, T.	PDF	N/A	A single theory for the evolution of sex chromosomes and the two rules of speciation
动物物种间SARS-CoV-2的宿主内遗传多样性	Naderi, S.	PDF	N/A	Within-host genetic diversity of SARS-CoV-2 across animal species
不同的秀丽隐杆线虫毒素等位基因通过不同的机制被抑制	Zdraljevic, S.	PDF	N/A	Divergent C. elegans toxin alleles are suppressed by distinct mechanisms
CetZ1依赖的极性运动机器在嗜盐古菌中的组装	Brown, H. J.	PDF	N/A	CetZ1-dependent polar assembly of the motility machinery in haloarchaea
MYB68调控径向内胚层分化及木栓质模式形成	Kraska, L.	PDF	N/A	MYB68 regulates radial endodermal differentiation and suberin patterning
KCa3.1的早期新型精氨酸甲基化减弱了后续T细胞的耗竭。	Sharma, P.	PDF	N/A	An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion.
降低腹内侧下丘脑（VMH）中神经型一氧化氮合酶（nNOS）的表达会增加雌性小鼠的体重和血糖水平，同时降低其身体活动。	Hirschberg, P. R.	PDF	N/A	Reducing neuronal nitric oxide synthase (nNOS) expression in the ventromedial hypothalamus (VMH) increases body weight and blood glucose levels while decreasing physical activity in female mice.
可扩展、高质量工程化干细胞衍生的SIRPα-细胞外囊泡的双模态作用治疗急性肝衰竭	Kim, S.	PDF	N/A	Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure
控制Ins2基因活性和β细胞状态转换的信号转导通路	Chu, J.	PDF	N/A	Signal transduction pathways controlling Ins2 gene activity and β cell state transitions
鉴定用于神经退行性疾病治疗的新型小分子伴侣激活剂	Ho, A.	PDF	N/A	Identification of novel small molecule chaperone activators for neurodegenerative disease treatment
食管腺癌的化生前体状态代表了在发育中的食管中向短暂的上皮细胞状态的逆转。	Baker, S.	PDF	N/A	The metaplastic precursor state to oesophageal adenocarcinoma represents reversion to a transient epithelial cell state in the developing oesophagus
人类新生儿超越词汇的统计学习	Flo, A.	PDF	N/A	Statistical learning beyond words in human neonates
克服毒性：为何繁荣与衰退周期对非对抗性微生物有益	Wang, M.	PDF	N/A	Overcoming toxicity: why boom-and-bust cycles are good for non-antagonistic microbes
鳃组织活检的转录组分析以确定养殖大西洋鲑鱼海水存活率的预测标志物	Gronvold, L.	PDF	N/A	Transcriptomic profiling of gill biopsies to define predictive markers for seawater survival in farmed Atlantic salmon
增殖事件改善了造血干细胞中DNA损伤的积累，而不影响其功能。	Mehatre, S. H.	PDF	N/A	Proliferative events ameliorate DNA damage accumulation without affecting function in hematopoietic stem cells
物体非刚性的各向异性：皮层各向异性对高级感知的影响	Maruya, A.	PDF	N/A	Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy
本科生研究学生使用的ChatGPT辅助阅读协议	Sambar, M.	PDF	N/A	A ChatGPT Assisted Reading Protocol for Undergraduate Research Students
结构引导的循环嫁接技术提高了流感神经氨酸酶在疫苗开发中的表达和稳定性	Rijal, P.	PDF	N/A	Structure-Guided Loop Grafting Improves Expression and Stability of Influenza Neuraminidase for Vaccine Development
一种流行性Ralstonia solanacearum谱系的兴起及其宿主范围的扩展	Evseeva, D.	PDF	N/A	Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum
使用稳定同位素示踪法建模复合脂质稳态	Wessendorf-Rodriguez, K.	PDF	N/A	Modeling Compound Lipid Homeostasis Using Stable Isotope Tracing
在主要外排敲除系统中确定铜绿假单胞菌MexXY-OprM底物谱，揭示了不同的抗生素底物类别	Kavanaugh, L. G.	PDF	N/A	Determination of Pseudomonas aeruginosa MexXY-OprM substrate profile in a major efflux knockout system reveals distinct antibiotic substrate classes
基于纵向微生物组的可解释机器学习用于早期疾病结果预测中时变生物标志物的识别	Dai, Y.	PDF	N/A	Longitudinal Microbiome-based Interpretable Machine Learning for Identification of Time-Varying Biomarkers in Early Prediction of Disease Outcomes
罕见癌症靶点发现框架	Li, B.	PDF	N/A	A framework for target discovery in rare cancers
生物医学数据的AI准备：Bridge2AI建议	Clark, T.	PDF	N/A	AI-readiness for Biomedical Data: Bridge2AI Recommendations
听觉皮层中的正交频谱和时间包络表示	Takahashi, K.	PDF	N/A	Orthogonal spectral and temporal envelope representation in auditory cortex
海葵生命史中基质分子动力学	Bergheim, B. G.	PDF	N/A	Molecular dynamics of the matrisome across sea anemone life history
神经肌肉骨骼建模流程：基于MATLAB的OpenSim模型个性化与治疗优化功能	Hammond, C. V.	PDF	N/A	The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim
定义细胞类型特异性CTCF结合和染色质组织的基因组范围代码	Do, C.	PDF	N/A	A genome wide code to define cell-type specific CTCF binding and chromatin organization
微生物群落中的对抗作为一种觅食策略	Stubbusch, A. K. M.	PDF	N/A	Antagonism as a foraging strategy in microbial communities
脊椎动物R2逆转录转座子复合物在目标引导逆转录期间的结构及第二链切割后的结构	Thawani, A.	PDF	N/A	Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking
通过结构建模和分歧日期估算，理解植物和真菌病毒中RNA聚合酶的进化和功能关系	Gracy, J.	PDF	N/A	Understanding evolutionary and functional relationships of RNA polymerases in plant and fungal viruses through structural modeling and divergence date estimations
对玉米驯化过程中根系表型在特瓦坎新石器时代土壤中的演变进行计算机模拟分析	Lopez-Valdivia, I.	PDF	N/A	In silico analysis of the evolution of root phenotypes during maize domestication in Neolithic soils of Tehuacan
基于结冷胶的营养培养基增加了土壤微生物培养群的多样性	Kulikova, D.	PDF	N/A	Gellan gum-based nutrient medium increases the diversity of cultivated groups of soil microorganisms
与越南H5N1分离株相比，牛H5N1在小鼠中表现出增强的脑炎趋向性。	Goldin, K.	PDF	N/A	Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice
磁共振R2*捕捉中风后不连续脑结构中的炎症：一项转化研究	Koubiyr, I.	PDF	N/A	MRI R2* captures inflammation in disconnected brain structures after stroke: a translational study
在BSL2级别下，使用直接薄层琼脂进行结核分枝杆菌对贝达喹啉的敏感性测试，从痰液处理开始15天内可获得高准确性。	Cuella Martin, I.	PDF	N/A	Direct thin-layer agar for bedaquiline-susceptibility testing of Mycobacterium tuberculosis at BSL2 level yields high accuracy in 15 days from sputum processing.
野生大麦多样性全基因组测序：用于鉴定和利用遗传变异以改良栽培大麦的资源	Sallam, A. H.	PDF	N/A	Whole-Genome Sequencing of the Wild Barley Diversity Collection: A Resource for Identifying and Exploiting Genetic Variation for Cultivated Barley Improvement
基于基因表达的膀胱癌淋巴结转移预测因子评估	Johansson, H. B.	PDF	N/A	Evaluation of gene expression-based predictors of lymph node metastasis in bladder cancer
委内瑞拉十一种无尾两栖动物的体型变异与性二态性	Canizales, I.	PDF	N/A	Body Size Variation And Sexual Dimorphism In Eleven Species Of Venezuelan Anurans
分子脑老化新多基因风险评分的神经结构和认知特征	Clifford, K. P.	PDF	N/A	Neurostructural and cognitive signatures of novel polygenic risk scores for molecular brain aging
内源性LINE-1蛋白及ORF2p相互作用的靶向检测	Nielsen, M. I.	PDF	N/A	Targeted detection of endogenous LINE-1 proteins and ORF2p interactions
Nano3P-seq：以单分子分辨率绘制编码和非编码转录组图谱	Begik, O.	PDF	N/A	Nano3P-seq: charting the coding and non-coding transcriptome at single molecule resolution
SuperWater：利用生成式AI预测蛋白质结构上的水分子位置	Kuang, X.	PDF	N/A	SuperWater: Predicting Water Molecule Positions on Protein Structures by Generative AI
通过抑制或降解LZK来靶向GOF p53和c-MYC抑制头颈肿瘤生长	Funk, A. L.	PDF	N/A	Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth
发育程序中的重复超基序电路	Adler, M.	PDF	N/A	Recurrent hyper-motif circuits in developmental programs
AZIN2依赖的多胺代谢决定脂肪细胞前体细胞的命运，并保护机体免受肥胖和代谢紊乱的影响。	Mund, C.	PDF	N/A	AZIN2-dependent polyamine metabolism determines adipocyte progenitor fate and protects against obesity and dysmetabolism
冰滑硅藻创下了真核细胞运动最低温度限制的纪录	Zhang, Q.	PDF	N/A	Ice gliding diatoms establish record-low temperature limit for motility in a eukaryotic cell
Boltz-1：使生物分子相互作用建模民主化	Wohlwend, J.	PDF	N/A	Boltz-1: Democratizing Biomolecular Interaction Modeling
修改聚集状态可能会提高Ozempic的活性。	Bolano Alvarez, A.	PDF	N/A	Modifying the aggregation state may improve the activity of Ozempic
片状伪足中动态稳态的机制	Kim, J. H.	PDF	N/A	The Mechanism of Dynamic Steady States in Lamellipodia
细胞分裂过程中染色体形态的渐进变化，通过环捕获模拟再现	Kakui, Y.	PDF	N/A	Progressive chromosome shape changes during cell divisions, recapitulated by loop capture simulations
通过细胞内丝状体感知表面形状	Shi, H.	PDF	N/A	Sensing the shape of a surface by intracellular filaments
分枝杆菌脂阿糖甘露聚糖负向干扰巨噬细胞对烟曲霉的体外反应	Gonzales-Huerta, L. E.	PDF	N/A	Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro
精氨酸调控超毒力肺炎克雷伯菌的黏液表型	Ring, B. E.	PDF	N/A	Arginine Regulates the Mucoid Phenotype of Hypervirulent Klebsiella pneumoniae
学习单细胞转录组数据的多细胞表示，有助于表征患者层面的疾病状态。	Liu, T.	PDF	N/A	Learning multi-cellular representations of single-cell transcriptomics data enables characterization of patient-level disease states
外周来源巨噬细胞的命运图谱揭示，在创伤性脑损伤后长达8个月的时间里，存在一群持久植入的细胞，这些细胞维持着独特的转录组特征。	Paladini, M. S.	PDF	N/A	Fate mapping of peripherally derived macrophages reveals a long-lasting engrafted population that maintains a distinct transcriptomic profile for up to 8 months after Traumatic Brain Injury
根瘤菌能否缓解豆科植物受到气候介导的微生物群落效应的影响？	Boyle, J. A.	PDF	N/A	Do rhizobia buffer legumes against climate-mediated microbiome effects?
揭示隐藏的盛宴：将分子检测转化为捕食率——农业生态系统中广食性捕食者生物防治的一个实例。	MASSON, A. L.	PDF	N/A	Unveiling the Hidden Feast: translating molecular detection into predation rate. An example on biological control by generalist predators in agricultural fields.
伊维菌素残留对粪便昆虫的依赖于环境背景的影响：与环境压力源、体型和性别在一种腐蝇（Sepsis neocynipsea）中的相互作用	Walker, J.	PDF	N/A	Context-dependent effects of ivermectin residues on dung insects: Interactions with environmental stressors, size, and sex in a sepsid fly (Sepsis neocynipsea)
关于非随机交配、适应性进化与信息论	Carvajal-Rodriguez, A.	PDF	N/A	On non-random mating, adaptive evolution and information theory
行波划动在雷诺数变化四个数量级的情况下仍能提供强大的推进性能。	Ford, M. P.	PDF	N/A	Metachronal rowing provides robust propulsive performance across four orders of magnitude variation in Reynolds number
利用AlphaFold 3进行神经疾病相关蛋白质的结构建模：通向精准医学的路径	Gadde, N.	PDF	N/A	Leveraging AlphaFold 3 for Structural Modeling of Neurological Disorder-Associated Proteins: A Pathway to Precision Medicine
使用向量符号架构进行特征选择：结直肠癌 shotgun 宏基因组样本微生物特征的案例研究	Cumbo, F.	PDF	N/A	Feature selection with vector-symbolic architectures: a case study on microbial profiles of shotgun metagenomic samples of colorectal cancer
原子模拟揭示线粒体ATP合酶中ATP酶抑制因子1的旋转方向依赖性调控	Kobayashi, R.	PDF	N/A	Rotation-direction-dependent regulation of ATPase inhibitory factor 1 for mitochondrial ATP synthase from atomistic simulation
癌症相关DAXX突变揭示了ATRX定位在ALT抑制中的关键作用	Clatterbuck Soper, S. F.	PDF	N/A	Cancer-associated DAXX mutations reveal a critical role for ATRX localization in ALT suppression
网络毒理学聚焦研究无机砷和镉对人类和生态系统健康的影响	Chivukula, N.	PDF	N/A	Network toxicology focused investigation on the impacts of inorganic arsenic and cadmium on human and ecosystem health
Sigma配体介导的BV2小胶质细胞胞质钙调制	Lodholz, E.	PDF	N/A	Sigma Ligand-mediated Cytosolic Calcium Modulation in BV2 Microglia Cells
一个TORC1-PHR1信号轴调控拟南芥中的磷饥饿与免疫信号网络	Awasthi, P.	PDF	N/A	A TORC1-PHR1 signaling axis regulates phosphorus starvation and immunity signaling network in Arabidopsis
转录反终止作用整合了在嵌合的巴尔通体基因转移因子BaGTA中源自不同噬菌体基因座的表达	Korotaev, A.	PDF	N/A	Transcriptional antitermination integrates the expression of loci of diverse phage origin in the chimeric Bartonella Gene Transfer Agent BaGTA
优化从鼻腔衬液中提取DNA以使用第三代测序评估鼻腔微生物群	Montgomery, S. T.	PDF	N/A	Optimisation of DNA extraction from nasal lining fluid to assess the nasal microbiome using third-generation sequencing
丝状化图谱揭示了几个转录调控因子，这些因子导致了白色念珠菌和都柏林念珠菌之间的差异。	Meza-Davalos, T.	PDF	N/A	Filamentation profile reveals several transcription regulators that contribute to differences between Candida albicans and Candida dubliniensis
人巨细胞病毒pp65的蛋白质-S-亚硝基化降低了其削弱cGAS的能力。	Cox, J. B.	PDF	N/A	Protein-S-Nitrosylation of Human Cytomegalovirus pp65 Reduces its Ability to Undermine cGAS.
通过灵活的顺反相互作用快速重塑古菌转录因子功能	Martinez-Pastor, M.	PDF	N/A	Rapid rewiring of an archaeal transcription factor function via flexible cis-trans interactions
JN.1单价mRNA疫苗诱导了针对包括JN.1、KP.3.1.1和XEC在内的广泛SARS-CoV-2 Omicron亚变种的强健抗病毒体液免疫。	Uriu, K.	PDF	N/A	Robust antiviral humoral immunity induced by JN.1 monovalent mRNA vaccines against a broad range of SARS-CoV-2 Omicron subvariants including JN.1, KP.3.1.1 and XEC
结合CRISPR激活和干扰能力，利用dCas9和G-四链体结构	Kabir, M. L.	PDF	N/A	Combining the CRISPR Activation and Interference Capabilities Using dCas9 and G-Quadruplex Structures
一种综合方法：研究蜱虫幼虫和若虫叮咬小鼠以探讨莱姆病传播与感染	Scholl, A.	PDF	N/A	A Comprehensive Method on Black-legged Tick Larvae and Nymph Feeding on Mice to Study Lyme Disease Transmission and Acquisition
组蛋白修饰和转座元件在基因重复后剂量表观遗传调控中的作用	Wolfe, T. D.	PDF	N/A	The role of histone modifications and transposable elements in the epigenetic regulation of dosage after gene duplication
复杂性状尾部的多基因结构显著偏离	Souaiaia, T.	PDF	N/A	Striking Departures from Polygenic Architecture in the Tails of Complex Traits
环节动物管虫Galeolaria caespitosa的分阶段染色体水平基因组	Van Dorssen, M.	PDF	N/A	A phased chromosome-level genome of the annelid tubeworm Galeolaria caespitosa
大肠杆菌天冬氨酸转氨甲酰酶的核苷酸依赖性变构调节机制	Miller, R. C.	PDF	N/A	Mechanism of Nucleotide-Dependent Allosteric Regulation in Escherichia coli Aspartate Transcarbamoylase
卵巢癌失调的长非编码RNA中的G四链体结构及其与人血清白蛋白的结合相互作用	Singh, D.	PDF	N/A	G-quadruplex Structures in Dysregulated Long Non-Coding RNA of Ovarian Cancer and their Binding Interactions with Human Serum Albumin
经过工程改造的线粒体A-to-G编辑器，具有增强的效率和靶向范围	Chen, L.	PDF	N/A	Engineered mitochondrial A-to-G editors with enhanced efficiency and targeting scope
通过可植入无线OLEDs进行深部器官癌症的光动力疗法	Itazaki, Y.	PDF	N/A	Photodynamic Therapy for Deep Organ Cancer by Implantable Wireless OLEDs
计算机辅助多层次优化假单胞菌中丙二酰辅酶A的可用性	Batianis, C.	PDF	N/A	Computer assisted multi-level optimization of malonyl-CoA availability in Pseudomonas putida
发现组织和维持神经回路的可塑性规则	Bell, D.	PDF	N/A	Discovering plasticity rules that organize and maintain neural circuits
肽聚合物二级结构在抗菌效力和抗生素增效中的作用	Barman, S.	PDF	N/A	The role of secondary structures of peptide polymers on antimicrobial efficacy and antibiotic potentiation
古菌细胞周期的转录图谱在真核生物中广泛保守	Gomez-Raya-Vilanova, M. V.	PDF	N/A	Transcriptional landscape of the archaeal cell cycle is broadly conserved in eukaryotes
化学恒化培养法可降低粪便真核病毒载量，并延缓病毒组移植后的腹泻发生。	Offersen, S. M.	PDF	N/A	Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation
在基于肠道的阿尔茨海默病果蝇模型中产生的Abeta聚集物的多样性	Elovsson, G.	PDF	N/A	Diversity of Abeta aggregates produced in a gut-based Drosophila model of Alzheimer's disease
心脏p38抑制突显磷酸蛋白质组在心力衰竭进展中的作用	Sedighi, S.	PDF	N/A	Inhibition of Cardiac p38 Highlights the Role of the Phosphoproteome in Heart Failure Progression
SARS-CoV-2 Spike蛋白跨膜区的序列和结构完整性对于病毒进入宿主细胞至关重要。	Ortiz-Mateu, J.	PDF	N/A	The sequence and structural integrity of the SARS-CoV-2 Spike protein transmembrane domain is crucial for viral entry
一种可诱导Cre和Flp组合重组的顺序事件响应型荧光报告系统	Pessina, G.	PDF	N/A	A sequential event-responsive fluorescent reporter for inducible Cre and Flp combinatorial recombination
人类eIF2A在翻译起始和uORF介导的翻译调控中起着微小的作用。	Teleman, A. A.	PDF	N/A	Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control
冷诱导的GOT1在棕色脂肪组织中激活苹果酸-天冬氨酸穿梭，以支持对脂肪酸的燃料偏好。	Park, C.-H.	PDF	N/A	Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids
对多样性杂交小鼠研究中的寿命进行分析，发现了多个与长寿相关的基因座	Mullis, M. N.	PDF	N/A	Analysis of lifespan across Diversity Outbred mouse studies identifies multiple longevity-associated loci
PHRF1的PHD指对组蛋白H3 N端识别对于适当的DNA损伤反应是必需的。	Jain, K.	PDF	N/A	Histone H3 N-terminal recognition by the PHD finger of PHRF1 is required for proper DNA damage response
SPO11二聚化调控减数分裂DNA双链断裂的形成	Oger, C. A.	PDF	N/A	SPO11 dimerization controls meiotic DNA double-strand break formation
利用密度和能量引导评估，自动识别冷冻电镜数据中的小分子	Muenks, A.	PDF	N/A	Automated identification of small molecules in cryo-electron microscopy data with density- and energy-guided evaluation
一个评估肉类替代品的建议框架	Semper, C.	PDF	N/A	A proposed framework for evaluating meat alternatives
评估当前长读长宏基因组菌株解析工具的性能	Afolayan, A. O.	PDF	N/A	Assessing the performance of current strain resolution tools on long-read metagenomes
等离子体激活水对百脉根丛枝菌根共生关系的调节作用	Cortese, E.	PDF	N/A	Modulatory effect of plasma-activated water on arbuscular mycorrhizal symbiosis in Lotus japonicus
渔猫化学通讯的功能性见解：半水生栖息地适应的策略机制	Das, S.	PDF	N/A	Functional insights on chemical communication of fishing cats: a strategic mechanism for adaptation in semi-aquatic habitat
多模态测量的整合揭示了结核病药物作用的关键机制	Johnson, W. C.	PDF	N/A	Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action
移植地点对在家与在医院接受造血干细胞移植患者的肠道微生物群和抗性组的影响	Andermann, T. M.	PDF	N/A	The impact of transplant location on the gut microbiome and resistome in patients undergoing hematopoietic stem cell transplantation at home versus in the hospital
RNA聚合酶II亚基的过表达会引发基因组不稳定性并扰乱转录调控。	Sadurni, M. M.	PDF	N/A	RNA Polymerase II subunits overexpressions induce genome instability and deregulate transcription
基于多组学的2D和3D人类iPSC-心肌细胞胰岛素抵抗模型评估显示，其代谢和收缩功能障碍再现了糖尿病心肌病的特征。	Carter, R. D.	PDF	N/A	Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy.
浮游植物光合生理学揭示了特定深度的浮游动物摄食情况	Graff, J. R.	PDF	N/A	Phytoplankton Photophysiology Reveals Depth Specific Zooplankton Grazing
本地和入侵植物群落中蜱虫暴露风险的机制途径	Hiatt, D.	PDF	N/A	Mechanistic pathways of tick exposure risk in native and invaded plant communities
负韧性趋势导致地中海橡树物种更频繁的极端干旱	Vazquez, I. B.	PDF	N/A	Negative resilience trends to more frequent extreme droughts in Mediterranean oak species
# BioRxiv 2024-11-19 Papers

标题	作者	PDF链接	代码仓库	Title
将昆虫社会的基本概念适应于生物本体论的需求。	Silva, T. S. R.	PDF	N/A	Adapting fundamental concepts from insect societies to the demands of bio-ontologies.
通过咽部神经元对黑腹果蝇的盐味行为进行活动和状态依赖性调节	Kaushik, S.	PDF	N/A	Activity and state-dependent modulation of salt taste behavior via pharyngeal neurons in Drosophila melanogaster
语义控制的晚熟促进了概念的发展	Jackson, R. L.	PDF	N/A	Late maturation of semantic control promotes conceptual development
气味表征表明，在整个嗅觉系统中存在非线性处理过程。	Olivares, J.	PDF	N/A	Odorant representations indicate nonlinear processing across the olfactory system
有效的保护决策需要针对特定目的设计的模型：安大略省“火环”地区北美驯鹿的案例研究	Dyson, M. E.	PDF	N/A	Effective conservation decisions require models designed for purpose: a case study for boreal caribou in Ontario's Ring of Fire
BATCH-SCAMPP：批量缩放的系统发育放置大型树	Wedell, E.	PDF	N/A	BATCH-SCAMPP: Batch Scaled Phylogenetic Placement Large Trees
剖析咖啡因在裂殖酵母中的细胞周期调控、DNA损伤敏感性和寿命效应	Alao, J.-P.	PDF	N/A	Dissecting the cell cycle regulation, DNA damage sensitivity and lifespan effects of caffeine in fission yeast
阿尔茨海默病和重度抑郁症中的比较基因调控网络分析揭示了共享的核心调控回路	Puype, H.	PDF	N/A	Comparative gene regulatory network analysis in Alzheimer's disease and major depressive disorder identifies shared core regulatory circuits
帕金森病的分类及从皮脂挥发物组中描绘进展标志物	Walton-Doyle, C.	PDF	N/A	Classification of Parkinson's Disease and Delineating Progression Markers from the Sebum Volatilome
经验生态网络推断的不一致性受统计方法和输入数据维度的考虑所支配。	Kusch, E.	PDF	N/A	Inconsistencies of empirical ecological network inference are governed by considerations of statistical approaches and dimensions of input data
一种适用于慢性神经像素探针的可适应、可重复使用且轻便的植入物	Bimbard, C.	PDF	N/A	An adaptable, reusable, and light implant for chronic Neuropixels probes
解码视觉空间注意力控制	Meyyappan, S.	PDF	N/A	Decoding Visual Spatial Attention Control
评估不同突变发现方法之间的不一致体细胞变异，以最小化药物耐药性发现的假阴性结果	Lin, H.-F.	PDF	N/A	Evaluating discordant somatic calls across mutation discovery approaches to minimize false negative drug-resistant findings
小鼠听觉皮层中的多模态失配反应	Solyga, M.	PDF	N/A	Multimodal mismatch responses in mouse auditory cortex
使用扰动-观察对进行自动模型优化	Park, K. H.	PDF	N/A	Automated Model Refinement Using Perturbation-Observation Pairs
一个热力学框架，用于分析非平衡自组装和分支肌动蛋白网络中的力形态权衡	Rennert, E.	PDF	N/A	A thermodynamic framework for nonequilibrium self-assembly and force morphology tradeoffs in branched actin networks
活体成像揭示了哺乳动物原肠胚形成过程中协调的细胞迁移和心脏命运决定。	Abukar, S.	PDF	N/A	Live-imaging reveals Coordinated Cell Migration and Cardiac Fate Determination during Mammalian Gastrulation.
单细胞多组学揭示了细胞周期中mRNA代谢和染色质可及性的振荡动力学	Nariya, M. K.	PDF	N/A	Single-cell multiomics reveals the oscillatory dynamics of mRNA metabolism and chromatin accessibility during the cell cycle
重复的行为进化与洞巢鸣禽基因表达的定向趋同有关	Lipshutz, S. E.	PDF	N/A	Repeated behavioral evolution is associated with targeted convergence of gene expression in cavity-nesting songbirds
双分病毒内体膜靶向中VP3-PI3P相互作用的作用	Zanetti, F. A.	PDF	N/A	On the Role of VP3-PI3P Interaction in Birnavirus Endosomal Membrane Targeting
抗-B7H3 CAR-T结构的功能亲和力预测了触发效应功能的抗原密度阈值	Barisa, M.	PDF	N/A	Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function
NAD+激活肾脏代谢，并在Alport综合征模型中保护免受慢性肾脏疾病的侵害。	Jones, B. A.	PDF	N/A	NAD+ activates renal metabolism and protects from chronic kidney disease in a model of Alport syndrome
使用QCM-D解码新兴肌动肌球蛋白交叉对话的机械化学影响	Kerivan, E. M.	PDF	N/A	Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk using QCM-D
通过综合分析基因表达数据识别胶质母细胞瘤的潜在治疗靶点和生物标志物	Bautista, A.	PDF	N/A	Identification of Potential Therapeutic Targets and Biomarkers for Glioblastomas Through Integrative Analysis of Gene Expression Data
通过函数分配的掩码超串实现高效的k-Mer集合操作	Sladky, O.	PDF	N/A	Towards Efficient k-Mer Set Operations via Function-Assigned Masked Superstrings
嗜水气单胞菌CobQ是一种新型的不依赖NAD+和Zn2+的蛋白质赖氨酸去乙酰化酶。	Wang, Y.	PDF	N/A	Aeromonas hydrophila CobQ is a new type of NAD+- and Zn2+-independent protein lysine deacetylase
一段基因组复制跨越多个P450基因，有助于登革热蚊子埃及伊蚊的杀虫剂抗性	Bacot, T.	PDF	N/A	A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
体感诱发电位在啮齿动物中引起广泛的弥散度和峰度变化，这些变化与神经活动相关。	Hertanu, A.	PDF	N/A	Somatosensory-evoked response induces extensive diffusivity and kurtosis changes associated with neural activity in rodents
围产期结构丘脑皮质连接的发展	Oldham, S.	PDF	N/A	Perinatal development of structural thalamocortical connectivity
持续的疫苗暴露能更快、更一致且更广泛地激发对多价流感疫苗的体液免疫反应。	Saouaf, O. M.	PDF	N/A	Sustained vaccine exposure elicits more rapid, consistent, and broad humoral immune responses to multivalent influenza vaccines
大脑中双向网络核心与感知觉意识和认知的关联	Taguchi, T.	PDF	N/A	Association of bidirectional network cores in the brain with perceptual awareness and cognition
96孔聚丙烯酰胺凝胶用于电泳和Western印迹	Birtwistle, M. R.	PDF	N/A	A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting
多结构域信号蛋白的深度突变扫描揭示了调控机制和致病性	Jiang, Z.	PDF	N/A	Deep mutational scanning of a multi-domain signaling protein reveals mechanisms of regulation and pathogenicity
海马体在类别抽象过程中支持向新状态的插值	Schaefer, T. A.	PDF	N/A	The hippocampus supports interpolation into new states during category abstraction
一种用于在低功耗神经形态硬件上监测癫痫发作的事件驱动神经网络	Bartels, J.	PDF	N/A	An event-driven neural network for monitoring of epileptic seizures on low-power neuromorphic hardware
环二腺苷酸驱动沙眼衣原体发育周期的进展	Lee, J.	PDF	N/A	Cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis
组成性激活的受体ADGRA3信号传导诱导脂肪组织产热	Zhao, Z.	PDF	N/A	Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis
评估漂变和选择在沿海拔梯度特征丧失中的作用	Buysse, S. F.	PDF	N/A	Evaluating the Roles of Drift and Selection in Trait Loss along an Elevational Gradient
特定的突触前功能需要不同的果蝇Cav2剪接异构体	Bell, C.	PDF	N/A	Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms
通过抑制NLRP3炎症小体，被caspase-11/4切割的VgrG2b片段促进了铜绿假单胞菌的感染。	Qian, Y.	PDF	N/A	A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome
基于模型的祖先比例更快速估算	Santander, C.	PDF	N/A	Faster model-based estimation of ancestry proportions
一种全面的蛋白质组结构系统方法揭示了所有人疱疹病毒蛋白质家族的见解	Soh, T. K.	PDF	N/A	A proteome-wide structural systems approach reveals insights into protein families of all human herpesviruses
桡足类化学信号对两种拟菱形藻属物种胞内和胞外毒素的影响	Pourdanandeh, M.	PDF	N/A	Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis
FuncFetch：一种由大型语言模型辅助的工作流程，能够从已发表的手稿中挖掘出数千种酶-底物相互作用	Smith, N.	PDF	N/A	FuncFetch: An LLM-assisted workflow enables mining thousands of enzyme-substrate interactions from published manuscripts
多物种全基因组CRISPR筛选鉴定出冷诱导细胞死亡的保守抑制因子	Lam, B.	PDF	N/A	Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
年龄相关的听觉脑干髓鞘缺陷会导致鸡尾酒会效应的缺陷。	Poleg, S.	PDF	N/A	Age-related myelin deficits in the auditory brain stem contribute to cocktail party-deficits
高度可扩展的物理交联水凝胶用于高速3D生物打印	Song, Y. E.	PDF	N/A	Highly extensible physically crosslinked hydrogels for high-speed 3D bioprinting
使用机器学习预测单克隆抗体的纯化工艺适用性	Maier, A. J.	PDF	N/A	Predicting purification process fit of monoclonal antibodies using machine learning
可移动元件通过细胞类型特异性的表观基因组关联影响人类调控景观	Hyacinthe, J.	PDF	N/A	Transposable elements impact the human regulatory landscape through cell type specific epigenomic associations
通过整合进化尺度和基于物理的建模来预测金属结合蛋白及其结构	Dai, X.	PDF	N/A	Predicting metal-binding proteins and structures through integration of evolutionary-scale and physics-based modeling
蛋白质工程竞赛结果：蛋白质建模与设计的开放科学基准	Armer, C.	PDF	N/A	Results of the Protein Engineering Tournament: An Open Science Benchmark for Protein Modeling and Design
内侧隔核和Broca斜带中的神经元异质性：类别与连续体	Kuhn, F.	PDF	N/A	Neuronal heterogeneity in the medial septum and diagonal band of Broca: classes and continua
细胞-细胞外基质（ECM）粘附的局部减弱通过改变细胞形状、肌动蛋白-肌球蛋白组织和E-钙粘蛋白水平，触发了基底组织的折叠。	Valencia-Exposito, A.	PDF	N/A	Local weakening of cell-ECM adhesion triggers basal tissue folding via changes in cell shape, actomyosin organization and E-cad levels
阿尔茨海默病突变型γ-分泌酶复合物阻碍了β-淀粉样肽的生成。	Arafi, P.	PDF	N/A	Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production
根据实验室观察，成熟的大黄蜂蛹在夜间仍会继续鸣叫。	FUJIOKA, H.	PDF	N/A	Mature larvae continue calling at night in Vespa mandarinia from laboratory observations
关于前向采样方案密度的近似严格下界	Kille, B.	PDF	N/A	A near-tight lower bound on the density of forward sampling schemes
遗传性铜缺乏和儿童神经退行性变模型中的适应性蛋白质合成	Lane, A. R.	PDF	N/A	Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
利用公开的数据非依赖采集数据集对人类组织中基线蛋白质表达的整合视图	Prakash, A.	PDF	N/A	Integrated View of Baseline Protein Expression in Human Tissues using public Data Independent Acquisition datasets
不同的持续时间和饮食依赖性脂质谱及GCK-MODY中的肾并发症	Huang, Y.	PDF	N/A	Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
DiffPaSS - 使用软分数进行高性能可微蛋白质序列配对	Lupo, U.	PDF	N/A	DiffPaSS - High-performance differentiable pairing of protein sequences using soft scores
多尺度光场显微镜平台，用于多功能动态体积生物成像	Bai, Y.	PDF	N/A	Multiscale Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bioimaging
CalTrig：一种基于图形用户界面的机器学习方法，用于解码自由活动啮齿动物中的神经元钙瞬变	Lange, M. A.	PDF	N/A	CalTrig: A GUI-based Machine Learning Approach for Decoding Neuronal Calcium Transients in Freely Moving Rodents
基于系统发育的模拟表明，在真核生物起源时期，未采样的谱系对基因流推断的影响较小。	Bernabeu, M.	PDF	N/A	Phylogeny-aware simulations suggest a low impact of unsampled lineages in the inference of gene flow during eukaryogenesis
用于高效遗传种群鉴定的特诺河大西洋鲑（Salmo salar）种群复合体的单核苷酸多态性基因分型面板	Johansson, H.	PDF	N/A	A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex
解读未开发古菌域中RiPPs的化学语言	Song, Z.-m.	PDF	N/A	Decoding the chemical language of RiPPs from the untapped Archaea domain
Vispro 提升了 Visium 空间转录组学的成像分析	Ma, H.	PDF	N/A	Vispro improves imaging analysis for Visium spatial transcriptomics
深度学习助力Pharos平台发现激酶药物靶点	Halasz, A. M.	PDF	N/A	Deep Learning enabled discovery of kinase drug targets in Pharos
利用-配对目标的RF扩散改进蛋白质结合剂设计	Sappington, I.	PDF	N/A	Improved protein binder design using -pairing targeted RFdiffusion
多站点研究中基于扩散MRI的结构连接组的协调	Shen, R. S.	PDF	N/A	Harmonization of Diffusion MRI-based Structural Connectomes for Multi-site Studies
赋予抗真菌药物抗性的RNAi表观突变是可遗传的。	Perez-Arques, C.	PDF	N/A	RNAi epimutations conferring antifungal drug resistance are inheritable
光照在弱电鱼的活动感知和控制中起着中介作用，能够调节其行为模式。	Yeh, H.	PDF	N/A	Illumination mediates a switch in both active sensing and control in weakly electric fish
全球范围内对预测模型进行基准测试，揭示长期中风结果的机制多样性	Matsulevits, A.	PDF	N/A	A global effort to benchmark predictive models and reveal mechanistic diversity in long-term stroke outcomes
SpotMAX：一种用于多维自动斑点检测和定量的通用框架	Padovani, F.	PDF	N/A	SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification
II型-B CRISPR-Cas9增强特异性的机制	Hibshman, G. N.	PDF	N/A	Mechanism of type II-B CRISPR-Cas9 enhanced specificity
在人细胞培养中5-氟尿嘧啶处理下RNA修饰的时间定位	Berg, M.	PDF	N/A	Temporal placement of RNA modifications under 5-fluorouracil treatment in human cell culture
一种跨越动物和环境的普遍海马体记忆编码	Wirtshafter, H. S.	PDF	N/A	A universal hippocampal memory code across animals and environments
跨动物和环境的海马体通用记忆编码	Wirtshafter, H. S.	PDF	N/A	A universal hippocampal memory code across animals and environments
使用多重竞争性等位基因特异性PCR（mxKASP）基因分型确定合子性	de Visser, M. C.	PDF	N/A	Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping
保守的基因内容和独特的系统发育历史特征了Triturus平衡致死系统背后的“bloopergene”	de Visser, M. C.	PDF	N/A	Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system
NewtCap：一种高效的目标捕获方法，用于提升蝾螈科（真蝾螈和新蝾螈）的基因组研究	de Visser, M. C.	PDF	N/A	NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts)
普通狨猴的拉绳行为	Bertrand, M.	PDF	N/A	String-pulling by the common marmoset
PAV-spotter：利用信号互相关识别目标捕获数据中的存在/缺失变异	de Visser, M. C.	PDF	N/A	PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data
保守的转录因子通过抑制作用协调突触基因的表达	Kentro, J. A.	PDF	N/A	Conserved transcription factors coordinate synaptic gene expression through repression
微生物转录对宿主饮食的反应维持了美洲大蠊肠道微生物群的稳态	DePoy, A. N.	PDF	N/A	Microbial transcriptional responses to host diet maintain gut microbiome homeostasis in the American cockroach
mcRigor：一种用于增强单细胞数据分析中metacell划分严谨性的统计方法	Liu, P.	PDF	N/A	mcRigor: a statistical method to enhance the rigor of metacell partitioning in single-cell data analysis
稀有物种并未过度贡献于亚高山植物群落的系统发育多样性	Veldhuisen, L. N.	PDF	N/A	Rare species do not disproportionately contribute to phylogenetic diversity in a subalpine plant community
秋水仙碱抑制小鼠平滑肌细胞表型转换及主动脉夹层	Jiang, H.	PDF	N/A	Colchicine Inhibits Smooth Muscle Cell Phenotypic Switch and Aortic Dissection in Mice
一种关于单细胞习惯化的受体失活模型，适用于蓝钟虫（Stentor coeruleus）	Rajan, D. H.	PDF	N/A	A receptor-inactivation model for single-celled habituation in Stentor coeruleus
全息层析显微镜揭示了在血管内皮化过程中，无需标记的血管内皮细胞定量动态变化。	Leineweber, W. D.	PDF	N/A	Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization
调节注意力网络中与学习相关的可塑性	Conto, F.	PDF	N/A	Modulation of learning-dependent plasticity in the attention network
基因重复后表达变异性的增加有助于基因的保留	Cai, H.	PDF	N/A	Expression variability following gene duplication facilitates gene retention
ROSIE：从组织病理学图像中生成多重免疫荧光染色的人工智能技术	Wu, E.	PDF	N/A	ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images
有丝分裂CIP2A-TOPBP1轴促进有丝分裂途径在MiDAS和MMEJ之间的选择。	Martin, P. R.	PDF	N/A	The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ
小窝蛋白-1和AQP4作为遗传性脑淀粉样血管病中纤维蛋白原驱动脑血管病理的介质	Singh, V.	PDF	N/A	Caveolin-1 and Aquaporin-4 as Mediators of Fibrinogen-Driven Cerebrovascular Pathology in Hereditary Cerebral Amyloid Angiopathy
表观遗传调节NLRP6炎症小体传感器作为一种治疗手段，以减少HIV/SIV感染中由坏死性凋亡驱动的胃肠黏膜功能障碍	Premadasa, L. S.	PDF	N/A	Epigenetic modulation of NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection
区分果蝇中轻度、重度及非典型过氧化物酶体生成障碍的PEX基因变异严重程度	Gomez, V. A.	PDF	N/A	Distinguishing PEX gene variant severity for mild, severe, and atypical peroxisome biogenesis disorders in Drosophila
无序玻璃纳米线基底通过光学衍射断层成像揭示了类似体内的星形胶质细胞形态	Anantha, P.	PDF	N/A	Disordered glass nanowire substrates produce in vivo-like astrocyte morphology revealed by optical diffraction tomography
一种伴有婴儿肠结肠炎的自发性炎症的动物模型	Wang, Y.	PDF	N/A	An animal model for autoinflammation with infantile enterocolitis
一种伴有婴儿肠结肠炎的自发性炎症动物模型	Wang, Y.	PDF	N/A	An animal model for autoinflammation with infantile enterocolitis
通过微活检皮肤样本在不同温度下的mRNA管家基因稳定性分析，推进远程和低资源医疗服务的提供	Nataren, N.	PDF	N/A	Advancing Remote and Low-Resource Healthcare Delivery with Microbiopsy Skin Sample mRNA Housekeeping Gene Stability Analysis Across Various Temperatures
酶约束的梅毒螺旋体代谢模型鉴定出甘油-3-磷酸脱氢酶作为替代电子受体	Shahreen, N.	PDF	N/A	Enzyme-constrained Metabolic Model of Treponema pallidum Identified Glycerol-3-phosphate Dehydrogenase as an Alternate Electron Sink
基质硬度决定人肺成纤维细胞中独特的阿霉素诱导的衰老相关分泌表型和转录组特征	Du, H.	PDF	N/A	Substrate Stiffness Dictates Unique Doxorubicin-induced Senescence-associated Secretory Phenotypes and Transcriptomic Signatures in Human Pulmonary Fibroblasts
磷脂酰乙醇胺是一种吞噬性配体，参与微生物胞外囊泡的结合和清除。	Kavianpour, A.	PDF	N/A	Phosphatidylethanolamine is a phagocytic ligand implicated in the binding and removal of microbial extracellular vesicles
补偿传感器运动延迟需要一个记忆缓冲区、一个状态观测器和一个预测器。	Maris, E.	PDF	N/A	Compensating for a sensorimotor delay requires a memory buffer, a state observer, and a predictor
氯离子稳态的动态变化在奖励学习过程中协调中脑抑制性网络活动	Woo, J.	PDF	N/A	Dynamic Changes in Chloride Homeostasis Coordinate Midbrain Inhibitory Network Activity during Reward Learning
使用多电极阵列对人类诱导多能干细胞衍生的感觉神经元进行分析，以用于镇痛药物筛选	Kuete, C. F.	PDF	N/A	Profiling Human iPSC-Derived Sensory Neurons for Analgesic Drug Screening Using a Multi-Electrode Array
近红外光疗法治疗神经退行性疾病的效果评估：穿透深度有限，可能影响疗效	Tittelmeier, J.	PDF	N/A	Evaluation of near-infrared light therapy for the treatment of neurodegenerative diseases: Limited penetration depth into the brain likely hinders efficacy
在刺激暴露期间，婴儿的大脑会迅速适应视觉统计规律。	Capparini, C.	PDF	N/A	The infant brain rapidly entrains to visual statistical regularities during stimulus exposure
前庭信号到初级视觉皮层（V1）的半球间和半球内来源	Bouvier, G.	PDF	N/A	Inter- and Intrahemispheric Sources of Vestibular Signals to V1
关于吸引力序列依赖背后的决策过程的神经证据	Shan, J.	PDF	N/A	Neural evidence for decision-making underlying attractive serial dependence
在呼气末二氧化碳质量较低时，使用屏气BOLD fMRI进行脑血管反应性振幅和延迟的定量映射	Clements, R. G.	PDF	N/A	Quantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO2 quality is low
优化肌萎缩侧索硬化症（ALS）患者脑室内人神经干细胞移植的非临床方案中的挑战与前景	Lombardi, I.	PDF	N/A	Challenges and promises in optimising a non-clinical protocol of intracerebroventricular human neural stem cell transplantation in ALS
通过药理学和遗传学方法揭示阿尔茨海默病中依赖与不依赖小胶质细胞的脑脂质代谢调控	Xu, Z.	PDF	N/A	Microglia-Dependent and Independent Modulation of Brain Lipid Metabolism in Alzheimer's Disease Revealed by Pharmacological and Genetic Microglial Depletion
行为风险模型解释了在虚拟高度行走时的运动和平衡变化	Seddighi, N.	PDF	N/A	Behavioral risk models explain locomotor and balance changes when walking at virtual heights
绘制DUSP6在ADHD iPSC衍生的多巴胺能神经元模型中的影响	Namipashaki, A.	PDF	N/A	Mapping the impact of DUSP6 in an ADHD iPSC derived-dopaminergic neuronal model
治疗朊病毒病的治疗窗口由朊蛋白的定时消耗定义	Bradford, B. M.	PDF	N/A	Therapeutic window for treatment of prion disease defined by timed depletion of Prion protein
靶向激活小胶质细胞PPARδ可重编程免疫代谢并增强饮食诱导肥胖中的胰岛素敏感性。	Jiao, H.	PDF	N/A	Targeted activation of microglial PPARdelta reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity.
顶叶经颅交流电刺激对时间预测的三角相位依赖性调制	Burke, R.	PDF	N/A	Delta phase-dependent modulation of temporal predictions by parietal transcranial alternating current stimulation
基于连接组学的特征选择性皮质回路模型	Buendia, V.	PDF	N/A	Connectome-based models of feature selectivity in a cortical circuit
沿着皮层层次对视觉区域进行多模态分层表征	Pizzuti, A.	PDF	N/A	Multimodal laminar characterization of visual areas along the cortical hierarchy
在发作性偏头痛患者中，攻击想象期间疼痛网络的激活受到干扰	Perdigao, A.	PDF	N/A	Disrupted activation of pain networks during attack imagery in patients with episodic migraine
GABA和甘氨酸在轴突切断的运动神经元细胞体上的突触释放，促进了运动轴突的再生。	Wood, R. L.	PDF	N/A	GABA and glycine synaptic release on axotomized motoneuron cell bodies promotes motor axon regeneration
在类似体内状态下树突突触整合模式	Ceballos, C. C.	PDF	N/A	Dendritic synaptic integration modes under in vivo-like states
生成网络模型未能准确捕捉到长程连接性。	Oldham, S.	PDF	N/A	Coming up short: generative network models fail to accurately capture long-range connectivity
拓扑异构酶3A（TOP3A）依赖的端粒延长替代机制（ALT）	KHANDAGALE, P. R.	PDF	N/A	Topoisomerase 3A (TOP3A) Dependent Alternative Lengthening of Telomeres (ALT)
CD40交联诱导的ERK激活促进了自噬，从而增强了宫颈癌细胞的放射敏感性。	Liu, B.	PDF	N/A	CD40 ligation-induced ERK activation promotes autophagy which leads to enhanced radiosensitivity in cervical carcinoma cells
抑制GEF-H1-RhoA信号通路在炎症中的作用：通过模拟RhoA67-78螺旋的钉合肽	Gathmann, C.	PDF	N/A	Inhibition of GEF-H1-RhoA signaling in inflammation with a stapled peptide mimicry of the RhoA67-78 helix
血管壁细胞保护成年大脑免受出血，但在发育中的斑马鱼中并不控制血脑屏障。	Baltaci, O. F.	PDF	N/A	Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish
动物社会网络分析中未测量变量的问题：基于边的多层次模型能否提供可靠的解决方案？	Bonnell, T.	PDF	N/A	The problem of unmeasured variables in animal social network analysis: can edge-based multilevel models provide a reliable solution?
阿尔茨海默病中的小胶质细胞状态易受衰老和胆固醇失调的影响	Li, B.	PDF	N/A	Microglia States are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's Disease
优化的人类诱导多能干细胞衍生的肝细胞的开发，以改善体外代谢疾病建模和毒性研究中的肝脏功能	Lukasiak, M.	PDF	N/A	Development of optimised human iPSC-derived hepatocytes with improved liver function for in vitro metabolic disease modelling and toxicity studies
体内人体子宫温度、pH值及子宫液成分分析	Tarahomi, M.	PDF	N/A	In vivo human uterine temperature, pH, and uterine fluid composition analysis
在调整淋巴细胞后，帕金森病全血RNA分析中SNCA表达的降低	Xu, K.	PDF	N/A	Decreased SNCA Expression in Whole-Blood RNA Analysis of Parkinson's Disease Adjusting for Lymphocytes
自闭症谱系障碍中的低代谢：来自脑部和血液转录组学的见解	Balasubramanian, R.	PDF	N/A	Hypometabolism in Autism Spectrum Disorder: Insights from Brain and Blood Transcriptomics
对加纳北部黄热病暴发的昆虫学调查	Osei, J. H. N.	PDF	N/A	Entomological investigations into yellow fever outbreak in northern Ghana
评估脑龄作为脑健康的特定标志	Tan, T. W. K.	PDF	N/A	Evaluation of Brain Age as a Specific Marker of Brain Health
从生物技术角度对源于真菌的抗菌药物进行综合文献计量研究	Da Silva, L. L.	PDF	N/A	A Comprehensive Bibliometric Investigation on Antimicrobials from Fungal Origins with a Biotechnological Perspective
埃塞俄比亚塔纳湖湖滨湿地综合湿地状况指数的开发与应用	Wondim, Y. K.	PDF	N/A	Development and use of integrated wetland condition index for lacustrine fringe wetlands of Lake Tana, Ethiopia
在问题解决过程中，眼睛和手的协同发音揭示了层级组织的规划。	Eluchans, M.	PDF	N/A	Eye and hand coarticulation during problem solving reveals hierarchically organized planning
在蛋白质组尺度上分析氨基酸替代揭示了癌症疾病中的新型蛋白质调控	Zhao, P.	PDF	N/A	Profiling amino acid substitution on proteomic scale unveils novel protein regulation in cancer diseases
双时间尺度电机电路动力学是快速头部探索行为和高效运动的基础	Li, P.	PDF	N/A	Dual-timescale motor circuit dynamics underlies fast head exploratory behavior and efficient locomotion
ELAVL3调控D1和D2纹状体中型多棘神经元中编码突触信号蛋白的RNA剪接。	Irmady, K.	PDF	N/A	ELAVL3 regulates splicing of RNAs encoding synaptic signaling proteins in D1 and D2 striatal medium spiny neurons.
Pick病中tau聚集体的分子多态性	Liu, J.	PDF	N/A	Molecular Polymorphism of tau aggregates in Pick's disease
CATSPERε的胞外域在发育过程中对CatSper的组装以及精子获能过程中的活性调节至关重要。	Hwang, J. Y.	PDF	N/A	Extracellular domains of CATSPERε are essential for CatSper assembly during development and activity modulation in sperm capacitation
学术交流中的骗局趋势	Faulkes, Z.	PDF	N/A	Trends in hoaxes of academic communication
病原体威胁的接近程度塑造了宿主在感染前反应中的胞外囊泡产生	Kolodziejska, K.	PDF	N/A	Pathogen threat proximity shapes host extracellular vesicle production in pre-infection response
静纤毛高度的变化可以解释外毛细胞束静息状态对钙的依赖性。	Chatterjee, R.	PDF	N/A	Stereocilium height changes can account for the calcium dependence of the outer-hair-cell bundle's resting state
利用临床试验数据和深度辅助学习优化三阴性乳腺癌新辅助治疗反应预测	Moon, C. I.	PDF	N/A	Optimizing Neoadjuvant Treatment Response Prediction for Triple-Negative Breast Cancer Using Clinical Trial Data and Deep Auxiliary Learning
姜黄素和胡椒碱通过模拟和人工智能方法预防和治疗乳腺癌的分析	Sivakumar, A.	PDF	N/A	Analysis of Curcumin and Piperine for Breast Cancer Prevention and Treatment via Simulation and Artificial Intelligence Methods
一种合成钾通道通过细胞自适应技术减轻氧化应激	Russo, A.	PDF	N/A	A synthetic potassium channel reduces oxidative stress 1 via cellular adaptronics
病理性α-突触核蛋白截断和突变对相分离的不同影响	Ray, S.	PDF	N/A	Divergent effects of pathological α-synuclein truncations and mutations on phase separation
通过体外重建揭示的染色质复制偶联对称组蛋白再循环的最小蛋白质列表	Nagae, F.	PDF	N/A	Minimal protein list for chromatin replication-coupled symmetric histone recycling revealed through in vitro reconstitution
具有全局抑制的决策集成伊辛模型	Tapinova, O.	PDF	N/A	Integrated Ising Model with global inhibition for decision making
PTK7靶向放射性核素治疗的临床前评估	Lindland, K.	PDF	N/A	Preclinical Evaluation of PTK7-Targeted Radionuclide Therapy
线性-二次模型（以及LQ模型的来源）的一个简单新替代方案	Bilinsky, L.	PDF	N/A	A simple new alternative to the linear-quadratic model (and where the LQ model comes from)
巴雷特食管和癌症的单细胞分析揭示了通过遗传易感性赋予风险的细胞类型	Wenzel, M. C.	PDF	N/A	Single cell analysis of Barrett's esophagus and carcinoma reveals cell types conferring risk via genetic predisposition
自监督学习发现的3446张全切片图像中切除的间皮瘤组织形态学图谱	Seyedshahi, F.	PDF	N/A	A histomorphological atlas of resected mesothelioma from 3446 whole-slide images discovered by self-supervised learning
mGluR同源和异源二聚体的独特药理学特性	McCullock, T. W.	PDF	N/A	Unique Pharmacology of mGluR homo- and heterodimers
对玉米驯化过程中根系表型演变的硅基分析——以特瓦坎新石器时代土壤为例	Lopez-Valdivia, I.	PDF	N/A	In silico analysis of the evolution of root phenotypes during maize domestication in Neolithic soils of Tehuacan
创新性突变筛选鉴定出TRANSPARENT TESTA7在种子油/蛋白质分配中的作用	Lecureuil, A.	PDF	N/A	Innovative mutant screening identifies TRANSPARENT TESTA7 as a player in seed oil/protein partitioning
X射线计算机断层扫描技术的应用彻底改变了土壤病原体的检测方式。	Pereira, E. C.	PDF	N/A	The use of X-ray Computed Tomography revolutionises soil pathogen detection
关于Farlowella colombiensis Retzer & Page 1997的分类地位及F. acus物种组（Loricariidae科：Loricariinae亚科）物种的评注。	Melo-Ortiz, O. E.	PDF	N/A	The taxonomic status of Farlowella colombiensis Retzer & Page 1997 with comments on species of the F. acus species group (Loricariidae: Loricariinae).
情绪通过偏差学习奖励可能性来影响信心	Mason, L.	PDF	N/A	Mood impacts confidence through biased learning of reward likelihood
健康成年和新生儿非裔美国人皮肤中IL1A/IRAK1轴及其下游促炎信号的激活	Trubetskoy, D.	PDF	N/A	Activation of IL1A/IRAK1 axis and downstream proinflammatory signaling in healthy adult and neonatal African American skin
与干扰素相关的B细胞过度活跃在携带Sm/RNP抗体的系统性红斑狼疮患者中高度富集。	Van Dooren, H. J.	PDF	N/A	IFN-associated B cell hyperactivity is highly enriched in SLE patients harboring Sm/RNP antibodies
囊性纤维化患者来源的铜绿假单胞菌菌株中噬菌体防御系统减少	van den Berg, D. F.	PDF	N/A	Reduced prevalence of phage defense systems in Pseudomonas aeruginosa strains from Cystic Fibrosis Patients
模拟人类子宫pH值和液体成分的胚胎培养基中的人类囊胚形成	Zagers, M. S.	PDF	N/A	Human blastocyst formation in an embryo culture medium mimicking human uterine pH and fluid composition
全球生物地理学与具叶绿体孢子蕨类的进化驱动力	Mellado-Mansilla, D.	PDF	N/A	GLOBAL BIOGEOGRAPHY AND EVOLUTIONARY DRIVERS OF FERNS WITH CHLOROPHYLLOUS SPORES
使用简单二分类器在FlowCAM中进行碎屑识别	Garcia-Oliva, O.	PDF	N/A	Detritus identification in FlowCAM using a simple binary classifier
互惠的主-沃尔巴克氏体相互作用塑造了单倍二倍体中细胞质不兼容性丧失后的感染持久性	KAUAI, F.	PDF	N/A	Reciprocal host-Wolbachia interactions shape infection persistence upon loss of cytoplasmic incompatibility in haplodiploids
使用卷积神经网络检测种间正选择	West, C.	PDF	N/A	Detecting interspecific positive selection using convolutional neural networks
鲸偶蹄目中上皮钠通道delta亚单位的进化路径表明其在钠感应中的作用	Zahnow, F.	PDF	N/A	The evolutionary path of the epithelial sodium channel delta-subunit in Cetartiodactyla points to a role in sodium sensing
有害突变可以促进性染色体间重组抑制的进化。	Jay, P.	PDF	N/A	Deleterious mutations can contribute to the evolution of recombination suppression between sex chromosomes
着丝粒附近的交叉会破坏减数分裂过程中同源染色体的正常分离。	Sen, S.	PDF	N/A	Centromere-proximal crossovers disrupt proper homologous chromosome disjunction during meiosis
优化多样化碱基编辑器以进行单核苷酸变异的高通量研究	Schwartz, C. I.	PDF	N/A	Towards optimizing diversifying base editors for high-throughput studies of single-nucleotide variants
时空T细胞追踪用于儿童癌症个性化TCR-T设计	Sentis, I.	PDF	N/A	Spatio-temporal T cell tracking for personalized TCR-T designs in childhood cancer
Id1促进功能丧失型Tet2小鼠的克隆性造血	Singh, S.	PDF	N/A	Id1 Promotes Clonal Hematopoiesis in Mice with Tet2 Loss of Function
准备用于核型分析和荧光原位杂交（FISH）的高质量番红花属植物染色体铺片	El-nagish, A.	PDF	N/A	Preparing high-quality chromosome spreads from Crocus species for karyotyping and FISH
可扩展的无细胞生产活性T7 RNA聚合酶	Rezvani, R. N.	PDF	N/A	Scalable cell-free production of active T7 RNA polymerase
哺乳动物大脑发育和进化中的双重计算系统	Imam, N.	PDF	N/A	Dual Computational Systems in the Development and Evolution of Mammalian Brains
人类和狨猴在基于形状的视觉面孔辨别行为中表现出相似的面孔识别特征。	Jeon, Y.-N.	PDF	N/A	Humans and marmosets share similar face recognition signatures in shape-based visual face discrimination behavior
利用扩散MRI中的基于模拟推理进行不确定性映射和概率性纤维束追踪：与经典贝叶斯方法的比较	Manzano-Patron, J. P.	PDF	N/A	Uncertainty mapping and probabilistic tractography using Simulation-Based Inference in diffusion MRI: A comparison with classical Bayes
面向多模态纵向分析：利用神经影像生物标志物、认知评估及人口统计数据预测认知衰退	Ashish, R. M.	PDF	N/A	Towards Multimodal Longitudinal Analysis for Predicting Cognitive Decline Using Neuroimaging Biomarkers, Cognitive Assessments, and Demographic Data
PIEZO2机械敏感性离子通道在脂肪感觉神经支配中起关键作用	Wang, Y.	PDF	N/A	A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation
时间预期调节额叶与感觉脑区之间的耦合	Nagy, P.	PDF	N/A	Temporal expectations modulate coupling between frontal and sensory brain areas
感觉丧失后关键期后的丘脑皮质连接的转录和生理适应	Iyer, L.	PDF	N/A	Post-Critical Period Transcriptional and Physiological Adaptations of Thalamocortical Connections after Sensory Loss
通过浦肯野细胞特异性删除Scn1b建立的发育性和癫痫性脑病小鼠模型	Guillen, F. I.	PDF	N/A	A novel mouse model for developmental and epileptic encephalopathy by Purkinje cell-specific deletion of Scn1b
脊椎动物的视觉起源于竞争的锥体电路。	Fornetto, C.	PDF	N/A	Vertebrate vision is ancestrally based on competing cone circuits
由激励驱动的可卡因觅药习惯与纹状体星形胶质细胞中多巴胺转运体的下调有关。	Fouyssac, M.	PDF	N/A	Compulsion derived from incentive cocaine-seeking habits is associated with a downregulation of the dopamine transporter in striatal astrocytes
敲低TTLL1可减轻Aβ诱导的人诱导多能干细胞衍生的皮层神经元中的TAU病理	Al Kabbani, M. A.	PDF	N/A	Knockdown of TTLL1 reduces Aβ-induced TAU pathology in human iPSC-derived cortical neurons
用于编码和解码与眼球运动相关神经活动的“眼反应函数”	Gehmacher, Q.	PDF	N/A	The "Ocular Response Function" for encoding and decoding oculomotor related neural activity
第二/三层连接的同向性偏差：自发、视觉和光遗传驱动的第一视皮层动态的统一机制	Rozsa, T.	PDF	N/A	Iso-orientation bias of layer 2/3 connections: the unifying mechanism of spontaneous, visually and optogenetically driven V1 dynamics
气味调节焦虑水平，但脑电图和心电图评估可能与主观报告存在差异	Morozova, M.	PDF	N/A	Scents Modulate Anxiety Levels, but Electroencephalographic and Electrocardiographic Assessments Could Diverge from Subjective Reports
听觉注意对唤醒的全球性和选择性影响：来自瞳孔扩张的洞察	Grandjean, A.	PDF	N/A	Global and selective effects of auditory attention on arousal: insights from pupil dilation
与骨关节炎相关的鞘脂类神经酰胺34:1在老鼠中引起炎症性疼痛	Rickman, R. H.	PDF	N/A	The osteoarthritis associated sphingolipid sphingomyelin 34:1 causes inflammatory pain in mice
体内CRISPR筛选鉴定出影响多发性骨髓瘤中CAR T细胞功能的关键修饰因子	Korell, F.	PDF	N/A	In vivo CRISPR screens identify key modifiers of CAR T cell function in myeloma
综合宏基因组学与血液生物标志物分析揭示了运动员和非运动员在有氧和无氧干预下的不同代谢反应	Zielinska, K.	PDF	N/A	Integrative Metagenomic and Blood Biomarker Analysis Reveals Distinct Metabolic Responses to Aerobic and Anaerobic Interventions in Athletic and Non-Athletic Individuals
肠道微生物及其代谢产物介导阻塞性睡眠呼吸暂停诱发的动脉粥样硬化	Xue, J.	PDF	N/A	Gut Microbiota and Derived Metabolites Mediate Obstructive Sleep Apnea Induced Atherosclerosis
基于结冷胶的营养培养基增加了土壤微生物培养群落的多样性	Kulikova, D.	PDF	N/A	Gellan gum-based nutrient medium increases the diversity of cultivated groups of soil microorganisms
大规模半自动化病毒传播定量分析揭示了斑块形成的多相结构	Howell, L. M.	PDF	N/A	Large scale semi-automated quantification of viral spread reveals multi-phasic structure of plaque formation
YTHDF1和YTHDC1 m6A阅读器蛋白调控HTLV-1 tax和hbz的活性	King, E. M.	PDF	N/A	YTHDF1 and YTHDC1 m6A reader proteins regulate HTLV-1 tax and hbz activity
RNA结合蛋白LIN28A在神经元分化过程中介导染色质动态变化	Piscitelli, S.	PDF	N/A	The RNA binding protein LIN28A mediates chromatin dynamics during neuronal differentiation
肥胖相关的MRAP2变异损害了多个MC4R介导的信号通路	Wyatt, R. A.	PDF	N/A	Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways
人类脊髓类器官揭示细胞插入作为次级神经胚形成的一种保守机制	Blanco-Ameijeiras, J.	PDF	N/A	HUMAN SPINAL CORD ORGANOIDS REVEAL CELL INTERCALATION AS A CONSERVED MECHANISM FOR SECONDARY NEURULATION
白海沿岸寡毛纲动物Lumbricillus sp.作为环节动物发育研究的模型	Matveicheva, E. P.	PDF	N/A	The White Sea littoral oligochaete Lumbricillus sp. as a model for annelid development studies
人类和小鼠造血干细胞的单细胞谱系偏向比较	Shamie, I.	PDF	N/A	Comparative single-cell lineage bias in human and murine hematopoietic stem cells
RNA编辑是未修饰人体细胞中的分子钟	Ghareeb, A. E.	PDF	N/A	RNA editing is a molecular clock in unmodified human cells
纳米孔测序技术在检测多种DNA修饰方面的关键评估	Kong, Y.	PDF	N/A	Critical assessment of nanopore sequencing for the detection of multiple forms of DNA modifications
空间解析活体CRISPR筛选测序通过Perturb-DBiT	Baysoy, A.	PDF	N/A	Spatially Resolved in vivo CRISPR Screen Sequencing via Perturb-DBiT
从RNA-蛋白质相互作用预测RNA稳定性的细胞类型特异性	Saran, S.	PDF	N/A	Cell-type specific prediction of RNA stability from RNA-protein interactions
构建一个互惠底物处理木质纤维二糖的共生假单胞菌菌群	Buryskova, B.	PDF	N/A	Building a syntrophic Pseudomonas putida consortium with reciprocal substrate processing of lignocellulosic disaccharides
开发一种针对自噬靶向降解的p62生物降解剂	Thiel, Z.	PDF	N/A	Development of a p62 biodegrader for autophagy targeted degradation
前外侧系统中表达生长抑素神经元的解剖学特征	Ma, W.	PDF	N/A	Anatomical characterisation of somatostatin-expressing neurons belonging to the anterolateral system
早期生命免疫激活塑造小胶质细胞反应并减少5xFAD小鼠的Aβ病理	Yang, Y.	PDF	N/A	Early-Life Immune Activation Shapes Microglial Responses and Reduces Abeta Pathology in 5xFAD mice
2024年5月老年人血清中针对SARS-CoV-2 KP.3.1.1和XEC的中和抗体水平较低	Fossum, E.	PDF	N/A	Low levels of neutralizing antibodies against SARS-CoV-2 KP.3.1.1 and XEC in serum from seniors in May 2024
CRAGE-RB-PI-seq技术能够在植物根系定殖过程中对根际细菌进行转录组分析。	Honda, T.	PDF	N/A	CRAGE-RB-PI-seq enables transcriptional profiling of rhizobacteria during plant-root colonization
微生物群的宿主起源驱动小鼠的功能恢复和艰难梭菌清除	Millard, S. A.	PDF	N/A	Host origin of microbiota drives functional recovery and Clostridioides difficile clearance in mice
与越南H5N1分离株相比，牛源H5N1在小鼠中表现出增强的脑炎趋向性。	Goldin, K.	PDF	N/A	Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice
PTBP1通过HIF-1α信号被寨卡病毒感染上调，并劫持NS1蛋白以诱导NS1降解，从而抑制病毒复制。	Rao, M.	PDF	N/A	PTBP1 is upregulated by Zika virus infection via HIF-1alpha signal and hijacks NS1 protein to induce NS1 degradation to restrain viral replication
一种无抗生素的抗菌组合：细菌素与肽聚糖水解酶的组合：体外和体内评估其功效	Kranjec, C.	PDF	N/A	An antibiotic-free antimicrobial combination of bacteriocins and a peptidoglycan hydrolase: in vitro and in vivo assessment of its efficacy
一种高度保守的小RNA在百日咳博德特菌的毒力模式中下调多个基因，包括一个sigma54转录激活因子。	Sim, M.	PDF	N/A	A highly conserved sRNA downregulates multiple genes, including a sigma54 transcriptional activator, in the virulence mode of Bordetella pertussis
小檗碱：一种兼具抗HIV和抗宫颈癌作用的化合物	Naushad, W.	PDF	N/A	Berberine: A dual anti-HIV and anti- cervical cancer compound
eDNA复制、聚合酶和扩增子大小影响跨栖息地丰富度的推断	Anmarkrud, J. A.	PDF	N/A	eDNA replicates, polymerase and amplicon size impact inference of richness across habitats
卵巢生殖干细胞的去分化依赖于细胞突起	Sutcliffe, C.	PDF	N/A	Ovarian germline stem cell dedifferentiation is cytoneme-dependent
内皮Rho激酶控制血管完整性和血管生成	Lange, M.	PDF	N/A	Endothelial Rho kinase controls blood vessel integrity and angiogenesis
连续定向酶进化的海市蜃楼：以植物化细菌THI4酶为例的警示性研究	Van Gelder, K.	PDF	N/A	Mirages in continuous directed enzyme evolution: A cautionary case study with plantized bacterial THI4 enzymes
用于病毒学研究的卡罗莱纳短尾蝠（Carollia perspicillata）细胞的病毒易感性和先天免疫能力	Gonzalez, V.	PDF	N/A	Viral susceptibility and innate immune competency of Carollia perspicillata bat cells produced for virological studies
SARM1激活通过两步液相到固相的相变促进轴突退化	Zhang, W.	PDF	N/A	SARM1 Activation Promotes Axonal Degeneration Via a Two-Step Liquid-to-Solid Phase Transition
# BioRxiv 2024-11-18 Papers

标题	作者	PDF链接	代码仓库	Title
已撤回：成年小鼠齿状回苔藓细胞对颗粒细胞和CA3区的兴奋性影响：体外和体内研究。	Bernstein, H. L.	PDF	N/A	WITHDRAWN: Excitatory effects of dentate gyrus mossy cells on granule cells and area CA3: an vitro and in vivo study in adult mice.
基于HHpred方法对SARS-CoV-2蛋白质进行重新注释，为更深入理解该病毒开启了新的机遇	Brezellec, P.	PDF	N/A	Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus
在小鼠决策过程中，先验信息的全脑表征	Findling, C.	PDF	N/A	Brain-wide representations of prior information in mouse decision-making
杜兴肌营养不良症（Duchenne Muscular Dystrophy）中成纤维细胞的包含导致疾病加重，MYOrganoids揭示了微肌营养不良蛋白治疗效力的局限性	Palmieri, L.	PDF	N/A	Disease exacerbation by fibroblast inclusion in Duchenne Muscular Dystrophy MYOrganoids reveals limitations of microdystrophin therapeutic efficacy
从孵化场到远洋：气候变化与鲑鱼海洋生存的关联	Kitada, S.	PDF	N/A	Hatcheries to high seas: climate change connections to salmon marine survival
scELMo：来自语言模型的嵌入在单细胞数据分析中是优秀的学习者	Liu, T.	PDF	N/A	scELMo: Embeddings from Language Models are Good Learners for Single-cell Data Analysis
可3D打印的非侵入性非人灵长类动物头部固定系统	Shahbazi, E.	PDF	N/A	3D-Printable Non-invasive Head Immobilization System for Non-Human Primates
撤回：人类胎盘中截短的NLRC5异构体：表达、由miR-218-5p调控及其在滋养层细胞中的功能	Shan, Y.	PDF	N/A	WITHDRAWN: Truncated NLRC5 isoforms in human placenta: expression, regulation by miR-218-5p, and function in trophoblasts
记忆元认知成分由楔前叶与海马之间高伽马活动所支持的结构构成	Pan, K.	PDF	N/A	Components of Mnemonic Metacognition Constitutionally Supported by High Gamma Activity Between the Precuneus and Hippocampus
两亲螺旋8的膜曲率关联驱动组成型GPCR内吞作用	Herlo, R.	PDF	N/A	Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis
超越皮层几何：罕见的长程连接塑造的大脑动力学	Vohryzek, J.	PDF	N/A	Beyond cortical geometry: brain dynamics shaped by rare long-range connections
人CD29+/CD56+肌源性前体细胞展现出向腱细胞分化的潜力，并能促进肌腱的再生。	Shao, X.	PDF	N/A	Human CD29+/CD56+ myogenic progenitors display tenogenic differentiation potential and facilitate tendon regeneration
肉食性动物的适应性景观揭示了头骨、附肢骨骼和轴向骨骼之间的功能权衡。	Law, C.	PDF	N/A	The carnivoran adaptive landscape reveals functional trade-offs among the skull, appendicular, and axial skeleton
一种新型进食机制：太阳鸟通过舌内吸力饮用花蜜	Cuban, D.	PDF	N/A	A novel feeding mechanism: Sunbirds drink nectar via intralingual suction
药物激活整合应激反应激酶抑制病理性线粒体碎片化	Baron, K. R.	PDF	N/A	Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation
发现猴痘病毒H3中的硫酸乙酰肝素结合域作为抗痘病毒药物靶点：结合AI与MD模拟	Zheng, B.	PDF	N/A	Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combining AI and MD Simulations
BiRNA-BERT通过自适应分词实现了高效的RNA语言建模	Tahmid, M. T.	PDF	N/A	BiRNA-BERT Allows Efficient RNA Language Modeling with Adaptive Tokenization
基于接触的胸苷酸转移促进集体肿瘤生长	Siddiqui, M. A.	PDF	N/A	Contact-based thymidylate transfer promotes collective tumor growth
拟南芥中亲本冲突对印记基因的影响。	Le veve, A.	PDF	N/A	The effect of parental conflict in imprinting genes in A. lyrata.
南方海獭（Enhydra lutris nereis）的理论咬合力和颌肌生长模式	Law, C.	PDF	N/A	Growth patterns of theoretical bite force and jaw musculature in southern sea otters (Enhydra lutris nereis)
河流无脊椎动物在景观中表现出时间生态过程的空间不对称性	Lin, X.	PDF	N/A	Riverine Invertebrates Exhibit Spatial Asymmetry in Temporal Ecological Processes Across Landscapes
SbcB 以不依赖核酸外切酶的方式促进霍乱弧菌的自然转化过程。	Dalia, T. N.	PDF	N/A	SbcB facilitates natural transformation in Vibrio cholerae in an exonuclease-independent manner
通过流形再现分析进行生成模型验证	Lazzaro, N.	PDF	N/A	Generative Models Validation via Manifold Recapitulation Analysis
西澳大利亚城市灌木丛火灾后的兰花输家和赢家：与其他特征深度融合的响应连续体	Brundrett, M. C.	PDF	N/A	Orchid losers and winners after fire in West Australian urban bushland: A response continuum deeply integrated with other traits
TFAP2C是调节子宫内滋养层细胞侵袭和深部血绒毛膜胎盘形成的关键因子。	Dominguez, E. M.	PDF	N/A	TFAP2C is a key regulator of intrauterine trophoblast cell invasion and deep hemochorial placentation
PPD-H1通过提高抗逆性和能量代谢，在高温环境下增强花粉活力	Lan, T.	PDF	N/A	PPD-H1 Improves Stress Resistance and Energy Metabolism to Boost Spike Fertility under High Ambient Temperatures
利用CryFold改进冷冻电镜图的自动模型构建	Su, B.	PDF	N/A	Improved automated model building for cryo-EM maps using CryFold
来自L. meyenii Walp的脂质纳米颗粒通过多模态蛋白质冠形成减轻脓毒症	Sung, J. J.	PDF	N/A	Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation
性特异性调控芬太尼奖赏的昼夜节律转录因子NPAS2	Barko, K.	PDF	N/A	Sex-specific Regulation of Fentanyl Reward by the Circadian Transcription Factor NPAS2
基于神经形态成像的人类血细胞计数	Zhang, Z.	PDF	N/A	Neuromorphic Imaging Cytometry on Human Blood Cells
NOTCH3激活机制的异质性揭示了针对CADASIL的靶向治疗潜力。	Hosseini-Alghaderi, S. S.	PDF	N/A	Heterogeneity of NOTCH3 activation mechanisms uncovers therapeutic potential for targeted therapies for CADASIL.
在早衰小鼠中，TFAM和线粒体DNA拷贝数操作引发的组织特异性反应	Kremer, L. S.	PDF	N/A	Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
多功能便携式Cas12a介导的抗生素抗性标记检测	Vargas-Reyes, M.	PDF	N/A	Versatile and Portable Cas12a-mediated Detection of Antibiotic Resistance Markers
高分辨率冷冻电镜展示了肠产毒性大肠杆菌中的I型和IV型菌毛结构的水合形态。	Nakamura, S.	PDF	N/A	High-resolution Cryo-EM visualises hydrated type I and IV pilus structures from enterotoxigenic Escherichia coli
线粒体调控巨核细胞-红细胞祖细胞的细胞命运决定	Sung, E.	PDF	N/A	Mitochondria Regulate the Cell Fate Decisions of Megakaryocyte-Erythroid Progenitors
成熟皮下脂肪细胞中的Wnt激活通过依赖于ATGL的脂解作用导致脂肪营养不良和皮肤纤维化。	Ma, Q.	PDF	N/A	Wnt activation in mature dermal adipocytes leads to lipodystrophy and skin fibrosis via ATGL-dependent lipolysis.
全球高致病性禽流感H5N1和H5Nx的风险地图：基于2020年以来发生的疫情事件	Dupas, M.-C.	PDF	N/A	Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onward
自动发现最优离散字符模型	Boyko, J.	PDF	N/A	Automatic Discovery of Optimal Discrete Character Models
一种与Haematomyzus elephantis共生的专性共生体，其基因组显著减少，类似于吸血虱中的共生细菌。	Rihova, J.	PDF	N/A	An obligate symbiont of Haematomyzus elephantis with a strongly reduced genome resembles symbiotic bacteria in sucking lice
新型增殖相关基因标志物在微卫星稳定型结直肠癌预后中的开发与验证	Wang, S.	PDF	N/A	Development and validation of novel proliferation-related gene signature for MSS colorectal cancer prognosis
自上而下的形状线索对半透明感知的影响	Nagai, T.	PDF	N/A	Top-Down Effects on Translucency Perception in Relation to Shape Cues
朊病毒安全实验室拭子测试	Simmons, S. M.	PDF	N/A	Prion safety laboratory swipe test
慢性鼻-鼻窦炎伴鼻息肉与不伴鼻息肉基因表达的比较	Kasem, M.	PDF	N/A	Comparison of Gene Expression between Chronic Rhinosinusitis with Nasal Polyposis and without Nasal Polyposis
特米尼洛山雪中的微塑料（意大利列蒂）	Pietrelli, L.	PDF	N/A	MICROPLASTICS IN THE MOUNT TERMINILLO SNOW (RIETI, ITALY)
预测与心肌梗塞和肺癌相关的双向分子预后特征：一种计算机模拟视角	Nandi, D. D.	PDF	N/A	Predicting Prognostic Bidirectional Molecular Signatures Associating Myocardial Infarction and Lung Cancer: An In-Silico Perspective
中性粒细胞胞外陷阱基因表达特征可识别胰腺肿瘤转移抑制的预后和可靶向信号轴	McDonald, P. C.	PDF	N/A	Neutrophil Extracellular Trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting metastasis of pancreatic tumours
单细胞表观遗传分析揭示了与肾癌中BAP1缺陷相关的干扰素应答高水平程序	Camp, S. Y.	PDF	N/A	Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer
比较儿童数学能力和流利度的神经认知机制：来自fNIRS研究的见解	Yeo, A. Y. N.	PDF	N/A	Comparing neurocognitive mechanisms of mathematical ability and fluency in children: insights from an fNIRS study
时间对感觉运动适应中的一个耗时、灵活的成分和一个快速、不灵活的成分产生影响。	Leow, L.-A.	PDF	N/A	Time affects a time-consuming, flexible component and a fast, inflexible component of sensorimotor adaptation.
蝙蝠的自组织声学行为源于简单的规则。	Hase, K.	PDF	N/A	Self-organized acoustic behavior in bats arises from simple rules
男性创业公司创始人的年龄标准化睾酮水平在B轮融资时达到峰值	Moradian, J.	PDF	N/A	Age-Normalized Testosterone Peaks at Series B for Male Startup Founders
生物催化领域的语言模型助手	Nana Teukam, Y. G.	PDF	N/A	A language model assistant for biocatalysis
癌基因诱导的衰老和衰老相关分泌表型（SASP）决定了帕博西尼在PIK3CA突变型结直肠癌中的疗效。	Cao, P.	PDF	N/A	Oncogene-induced senescence and senescence-associated secretory phenotype (SASP) determine the efficacy of palbociclib in PIK3CA mutated colorectal cancer
沿着一条欧洲小河进行的AI辅助慢性混合风险评估揭示了多个存在风险的地点，而药物是主要的驱动因素。	Weichert, F. G.	PDF	N/A	AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers
标准流靶向蛋白质组学用于硫代葡萄糖苷生物合成途径中酶的定量	Vik, D.	PDF	N/A	Standard-flow targeted proteomics for quantification of enzymes in glucosinolate biosynthetic pathways
网格到位置细胞连接性在十一个不同房间中的表现	Aggarwal, A.	PDF	N/A	Grid to Place Cell Connectivity in Eleven Different Rooms
空气-液体界面精密切割肺切片（PCLS-ALI）：一种用于研究肺曲霉病的新型体外模型	Gonzales-Huerta, L. E.	PDF	N/A	Precision-cut lung slices in air-liquid interface (PCLS-ALI): A novel ex-vivo model for the study of Pulmonary Aspergillosis
公平对待它：一种简单、快速且高效的方法，用于从死亡帽蘑菇（Amanita phalloides）中提取鹅膏毒素	Adams, C. A.	PDF	N/A	Giving it a fair shake: A simple, fast, & efficient method to extract amatoxins from the death cap mushroom, Amanita phalloides
长期平衡选择维持了青蛙的隐秘颜色多态性	Goutte, S.	PDF	N/A	Long-term balancing selection maintains cryptic color polymorphism in frogs
放射疗法在血液恶性肿瘤中的诱变影响和进化作用	Diamond, B.	PDF	N/A	Mutagenic impact and evolutionary influence of radiotherapy in hematologic malignancies
通过FDR控制肽身份传播，提高差异丰度蛋白质的检测能力	Solivais, A. J.	PDF	N/A	Improved detection of differentially abundant proteins through FDR-control of peptide-identity-propagation
静脉基因治疗可改善猫桑德霍夫病的寿命和临床结果	Maguire, A. S.	PDF	N/A	Intravenous gene therapy improves lifespan and clinical outcomes in feline Sandhoff Disease
阿尔茨海默病中溶酶体酶基因的不足	Benitez, B. A.	PDF	N/A	Haploinsufficiency of lysosomal enzyme genes in Alzheimers disease
标准学习与反馈延迟：来自计算模型和行为实验的见解	Crossley, M. J.	PDF	N/A	Criterial Learning and Feedback Delay: Insights from Computational Models and Behavioral Experiments
VNC-Dist：一种基于机器学习的工具，用于量化秀丽隐杆线虫腹神经索中神经元的位置	Saharkhiz, S.	PDF	N/A	VNC-Dist: A machine learning-based tool for quantification of neuronal positioning in the ventral nerve cord of C. elegans
评估无序区域边界处多聚XYs的螺旋稳定性与MD模拟	Goncalves-Kulik, M.	PDF	N/A	Assessing the helical stability of polyXYs at the boundaries of Intrinsically Disordered Regions with MD simulations
电场耦合使得动作电位的传导成为可能。	Waaben, J.	PDF	N/A	Ephaptic coupling enables action potential conduction
胰岛素/胰岛素样生长因子信号通路促进果蝇雌性更高的脂肪储存	Biswas, P.	PDF	N/A	Insulin/insulin-like growth factor signaling pathway promotes higher fat storage in Drosophila females
内侧颞叶中空间和价值的分布式编码	Yang, L.	PDF	N/A	Distributed coding of space and valence in the medial temporal lobe
感觉历史驱动LP/丘脑枕-前额叶皮层电路中的适应性神经几何结构	Leow, Y. N.	PDF	N/A	Sensory History Drives Adaptive Neural Geometry in LP/Pulvinar-Prefrontal Cortex Circuits
通过优化嗅觉记忆网络中的神经流形进行表征学习	Hu, B.	PDF	N/A	Representational learning by optimization of neural manifolds in an olfactory memory network
体内类似的无支架三维体外肌肉萎缩模型：个性化医学中锚定细胞片工程的案例	Shahin-Shamsabadi, A.	PDF	N/A	in vivo-like Scaffold-free 3D in vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine
黑鸟：使用合成和低覆盖率长读取进行结构变异检测	Meleshko, D.	PDF	N/A	Blackbird: structural variant detection using synthetic and low-coverage long-reads
蛋白质晶体结构和AlphaFold预测模型的分子表面的几何特性	Wang, L.	PDF	N/A	The geometric properties of the molecular surfaces of protein crystal structures and AlphaFold predicted models
用于增强非编码RNA分类的核苷酸序列生成方法	Chiquitto, A. G.	PDF	N/A	Generative Approaches for Nucleotide Sequences to Enhance Non-coding RNA Classification
阐明非同义替代对人胰岛淀粉样多肽构象变化的影响	Bashar, M. A.	PDF	N/A	Elucidating conformational alteration of human islet amyloid polypeptide by nonsynonymous substitution
在二叠纪末大灭绝后，中国低纬度地区的河流生态系统迅速恢复	Guo, W.	PDF	N/A	Rapid riparian ecosystem recovery in low-latitudinal North China following the end-Permian mass extinction
综合心血管对分级下肢负压的剂量反应	Whittle, R. S.	PDF	N/A	Integrative cardiovascular dose-response to graded lower body negative pressure
时间与催产素在有无妊娠糖尿病的小鼠和人类中的疗效交互作用	Duong, T. V.-Q.	PDF	N/A	Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes
从神经元到网络的非线性脑连接：量化、来源与定位。	Raffaelli, G. T.	PDF	N/A	Nonlinear brain connectivity from neurons to networks: quantification, sources and localization.
预测在观看电影过程中由前额叶皮层fNIRS信号引起的全脑神经动力学	Gao, S.	PDF	N/A	Predicting whole-brain neural dynamics from prefrontal cortex fNIRS signal during movie-watching
抑制Notch信号通路可减轻癫痫持续状态诱导的青春期大鼠脑内癫痫放电	Yuan, P.	PDF	N/A	Inhibition of Notch Signaling Attenuates Epileptic Discharges in the Adolescent Rat Brain after Status Epilepticus Induction
脂滴蛋白Perilipin 2通过胰腺胰岛中的β细胞脂噬作用和胰高血糖素表达，对胰岛素分泌的调控至关重要。	Liu, S.	PDF	N/A	Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets
毛发再生新技术：含外泌体的不同商业产品比较	Ferrugia, G.	PDF	N/A	New technologies for hair follicle growth and regeneration: comparison between different commercial products contain exosomes
Meioc-Piwil1复合物调控rRNA转录以促进精原干细胞的分化	Kawasaki, T.	PDF	N/A	Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells
利用基于视频的深度学习技术解析自然环境中的蜜蜂摇摆舞	Grison, S.	PDF	N/A	Unraveling Honey Bee's Waggle Dances in Natural Conditions with Video-Based Deep Learning
湿地草甸中刈割与覆盖对蜗牛群落影响的实验比较	Farkas, R.	PDF	N/A	Experimental comparison of mowing and mulching on snail communities in wet meadows
将性染色体系统与四足动物成年性别比例变化联系起来的群体统计学途径	Pipoly, I.	PDF	N/A	Demographic pathways linking sex-chromosome system to adult sex ratio variation across tetrapods
幼体营养不良下的扩散进化成本	Vibishan, B.	PDF	N/A	Costs of dispersal evolution under larval malnutrition
当性选择遇到遗传漂变：有限种群中雄性性状与雌性偏好的共同演化	Xu, K.	PDF	N/A	When sexual selection meets genetic drift: the coevolution of male traits and female preferences in finite populations
在安第斯山脉的拟似杂交区中，阿塔佩特斯刷嘴雀（雀形目，雀科）表现出表型变异和行为隔离的弱化。	Munoz-Quintana, G.	PDF	N/A	Phenotypic variation and weak behavioral isolation in a putative hybrid zone between Andean Atlapetes brushfinches (Passerellidae)
结合单核苷酸多态性（SNP）亲本单体型分析与强度分析，可识别出人类胚胎植入前期的减数分裂和有丝分裂非整倍体，以及频繁的片段非整倍体。	Handyside, A. H.	PDF	N/A	Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos
解析cfDNA片段化模式：将染色质结构与癌症诊断敏感性相联系	Johnston, A. D.	PDF	N/A	Unraveling cfDNA Fragmentation Patterns: Linking Chromatin Architecture to Cancer Diagnostic Sensitivity
Ca2+/钙调蛋白依赖性蛋白激酶II的α和β亚型在哺乳动物睡眠中的参与有限	Yang, W.	PDF	N/A	Limited involvement of Ca2+/calmodulin-dependent kinase II alpha and beta in mammalian sleep
含有三核苷酸重复序列的DNA通过噬菌体T7的复制体进行复制	Lee, S.-J.	PDF	N/A	Replication of DNA containing trinucleotide repeats by the bacteriophage T7 replisome
NK-92细胞对白色念珠菌的增强抗真菌活性通过甘露聚糖特异性嵌合抗原受体介导	Yamazaki de Campos, G.	PDF	N/A	Enhanced antifungal activity of NK-92 cells against Candida albicans mediated by a mannan-specific chimeric antigen receptor
使用生成模型进行概率性脑部MR图像变换	Rezvani, S.	PDF	N/A	Probabilistic Brain MR Image Transformation Using Generative Models
一种核酸前药能激活线粒体呼吸并延长寿命	Anada, T.	PDF	N/A	A nucleic acid prodrug activates mitochondrial respiration and extends lifespan
小尺寸植入式神经探针，配备高效倒装芯片微型LED，用于活体光遗传学研究	Abrantes, M.	PDF	N/A	Small form factor implantable neural probe with efficient flip chip micro LED for in vivo optogenetics
非人灵长类动物子宫各层在妊娠期间的时间依赖性材料特性和组成	Fodera, D. M.	PDF	N/A	Time-Dependent Material Properties and Composition of the Nonhuman Primate Uterine Layers Through Gestation
利用可解释的人工智能设计高效抗生物膜、抗菌肽	Pikalyova, K.	PDF	N/A	Design of highly potent anti-biofilm, antimicrobial peptides using explainable artificial intelligence
可解释的聚类性能指标	Mondal, K.	PDF	N/A	Physically Interpretable Performance Metrics for Clustering
Squidiff：利用扩散模型预测细胞发育及对扰动的响应	He, S.	PDF	N/A	Squidiff: Predicting cellular development and responses to perturbations using a diffusion model
Clair3-RNA：一种基于深度学习的用于长读长RNA测序数据的小变异检测工具	Zheng, Z.	PDF	N/A	Clair3-RNA: A deep learning-based small variant caller for long-read RNA sequencing data
AlphaFold 对整个基因组的预测概览	Cazals, F.	PDF	N/A	AlphaFold predictions on whole genomes at a glance
使用综合生物信息学方法鉴定结直肠癌中的潜在枢纽基因和治疗靶点	D, K.	PDF	N/A	Identification of Potential Hub Genes and Therapeutic Targets in Colorectal Cancer Using Integrated Bioinformatics Approaches
Pharming：从肿瘤单细胞DNA测序中联合克隆树重建SNV和CNA演化	Weber, L. L.	PDF	N/A	Pharming: Joint Clonal Tree Reconstruction of SNV and CNAEvolution from Single-cell DNA Sequencing of Tumors
基于深度学习的酶最适pH预测及通过点突变提高酸耐受性的设计	Qiu, S.	PDF	N/A	Deep learning-based prediction of enzyme optimal pH and design of point mutations to improve acid resistance
通过机器学习分析免疫单细胞RNA-seq数据，揭示预测检查点免疫治疗反应的基因和细胞特征	Pinhasi, A.	PDF	N/A	Uncovering Predictive Gene and Cellular Signatures for Checkpoint Immunotherapy Response through Machine Learning Analysis of Immune Single-Cell RNA-seq Data
MAX2泛素连接酶-受体-底物复合体协同独脚金内酯感知机制	Arold, S. T.	PDF	N/A	Mechanism of cooperative strigolactone perception by the MAX2 ubiquitin ligase-receptor-substrate complex
RNA动力学与相分离的中等分辨率模型，显式包含Mg²⁺	Li, S.	PDF	N/A	An Intermediate Resolution Model of RNA Dynamics and Phase Separation with Explicit Mg2+
基因编码纳米颗粒的单颗粒追踪：优化表达以进行细胞质扩散研究	Korunova, E.	PDF	N/A	Single Particle Tracking of Genetically Encoded Nanoparticles: Optimizing Expression for Cytoplasmic Diffusion Studies
RAS通路抑制剂与靶向药物的联合在多种癌症类型中具有致癌KRAS变异的源自患者的细胞球体中表现出活性。	Davoudi, Z.	PDF	N/A	Combinations of RAS pathway inhibitors with targeted agents are active in spheroids of patient-derived cells with oncogenic KRAS variants from multiple cancer types
工程化儿童肿瘤保留了患者肿瘤的基因型和表型，适用于精准医学。	Jung, M.	PDF	N/A	Engineered paediatric tumours retain patient tumour genotype and phenotype for precision medicine.
线粒体基因组编码的mitomiRs调控三阴性乳腺癌中的细胞可塑性和铁死亡敏感性	Kandettu, A.	PDF	N/A	Mitochondrial genome-encoded mitomiRs regulate cellular plasticity and susceptibility to ferroptosis in triple-negative breast cancer
通过提示语言模型实现多功能可控蛋白质生成	Wang, Z.	PDF	N/A	Multi-purpose controllable protein generation via prompted language models
高吞吐量蛋白质组学和磷酸蛋白质组学分析的福尔马林固定石蜡包埋组织	Haines, M.	PDF	N/A	High-throughput proteomic and phosphoproteomic analysis of formalin-fixed paraffin-embedded tissue
跨颈椎和腰椎脊髓的dI3神经元感觉运动回路图谱	Nasiri, S.	PDF	N/A	Mapping of dI3 neuron sensorimotor circuits across the cervical and lumbar spinal cord
增强电生理学研究中从场电位提取信息的能力	Akella, S.	PDF	N/A	Enhancing information extraction from field potentials in electrophysiology studies
同时失去CAMK2A和CAMK2B揭示了内源性体内底物	Rigter, P. M. F.	PDF	N/A	Simultaneous loss of CAMK2A and CAMK2B reveals endogenous in vivo substrates
受损的补体调节在肺移植后驱动慢性肺移植物功能障碍。	Kulkarni, H. S.	PDF	N/A	Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation.
孤立的小鼠成年心肌细胞表现出最低的线粒体ATP需求，并高度依赖糖酵解。	Mattam, U.	PDF	N/A	Isolated Mouse Adult Cardiomyocytes Display Minimal Mitochondrial ATP Demand and Maximal Reliance on Glycolysis
PRDM16-CtBP1/2复合物与HDAC1/2相互作用，调节神经发生转录程序并指导皮层神经元迁移	Warren, S.	PDF	N/A	A PRDM16-CtBP1/2 Complex Interacts with HDAC1/2 to Regulate Transcriptional Programs of Neurogenesis and Guide Cortical Neuron Migration
ILSM：用于分析三方交互网络互连结构的软件包	Sun, W.	PDF	N/A	ILSM: A package for analyzing the interconnection structure of tripartite interaction networks
在温度变化条件下果蝇发育时间的阶段特异性热塑性	Chattopadhyay, A.	PDF	N/A	Thermal Plasticity of Stage Specific Development Time in Drosophila melanogaster under Shifting Temperatures
推进远程与低资源医疗服务的进展：通过微生物活检皮肤样本在不同温度下对mRNA管家基因稳定性的分析	Falckenhayn, C.	PDF	N/A	Advancing Remote and Low-Resource Healthcare Delivery with Microbiopsy Skin Sample mRNA Housekeeping Gene Stability Analysis Across Various Temperatures
结合体细胞突变和基因表达的综合分析揭示了在DNA损伤应答下，牙龈颊癌中与核斑点相关的增强干细胞特性	Kumar, S.	PDF	N/A	Combined analysis of somatic mutations and gene expression reveals nuclear speckles-associated enhanced stemness in gingivobuccal carcinoma under DNA damage response
通过计算优化和结构工程显著提升接枝纳米抗体的抗病毒疗效	HUO, L.	PDF	N/A	Significantly enhancing antiviral efficacy by computational optimization and structural engineering of grafted nanobodies
质粒、前噬菌体和防御系统从植物微生物群基因组中被耗尽	Bograd, A.	PDF	N/A	Plasmids, Prophages and Defense Systems are Depleted from Plant Microbiota Genomes
单细胞图谱的分布保留压缩：实现隐私保护数据传播与新细胞类型发现	Cai, Z.	PDF	N/A	Distribution-preserved compression of single-cell atlases for privacy-protected data dissemination and novel cell type discovery
GOBoost：利用长尾基因本体论术语进行准确的蛋白质功能预测	Zhang, L.	PDF	N/A	GOBoost: Leveraging Long-Tail Gene Ontology Terms for Accurate Protein Function Prediction
CD73抑制子宫内膜癌中突变型β-连环蛋白的致癌活性	Hirsch, R. M.	PDF	N/A	CD73 restrains mutant β-catenin oncogenic activity in endometrial carcinomas
酶约束的梅毒螺旋体代谢模型鉴定出甘油-3-磷酸脱氢酶作为替代电子汇	Shahreen, N.	PDF	N/A	Enzyme-constrained Metabolic Model of Treponema pallidum Identified Glycerol-3-phosphate Dehydrogenase as an Alternate Electron Sink
人巨细胞病毒预融合样糖蛋白B亚单位疫苗在小鼠中引发的体液免疫反应与融合后gB相似	Karthigeyan, K. P.	PDF	N/A	A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits similar humoral immunity to that of postfusion gB in mice
一种定量方法揭示了痘病毒感染中抗原呈递和免疫原性的普遍相关性，适用于病毒CD8+ T细胞表位	Witney, M. J.	PDF	N/A	A quantitative approach to poxvirus infection reveals general correlates of antigen presentation and immunogenicity for viral CD8+ T cell epitopes
在金黄色葡萄球菌中，sRNA介导的细胞壁压力与半乳糖代谢之间的交叉对话	Germain, M.	PDF	N/A	sRNA-mediated crosstalk between cell wall stress and galactose metabolism in Staphylococcus aureus
结合活细胞荧光成像与原位冷冻电子断层扫描技术，揭示了耐辐射奇异球菌（Deinococcus radiodurans）的隔膜形成过程。	Gaifas, L.	PDF	N/A	Combining live cell fluorescence imaging with in situ cryo electron tomography sheds light on the septation process in Deinococcus radiodurans
SARS-CoV-2 亚变体 KP.3.1.1 和 XEC 的抗体逃逸性	Wang, Q.	PDF	N/A	Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC
结合代谢工程和发酵优化，通过Cutaneotrichosporon oleaginosus实现成本效益的油脂生产	Duman-Ozdamar, Z. E.	PDF	N/A	Combining metabolic engineering and fermentation optimization to achieve cost-effective oil production by Cutaneotrichosporon oleaginosus
癌症相关SF3B1突变K700E导致U2/分支点识别广泛变化，但不影响剪接。	Damianov, A.	PDF	N/A	Cancer-associated SF3B1 mutation K700E causes widespread changes in U2/branchpoint recognition without altering splicing.
生成 snoRNA 引导的可编程 2'O-甲基化	Zhao, J.	PDF	N/A	Generating snoRNA-guided Programmable 2'O-methylation
CDKL5激酶通过富含丝氨酸的C端区域进行液-液相分离，而与神经发育疾病相关的截断则会对其造成损害。	Dell'Oca, M.	PDF	N/A	The CDKL5 kinase undergoes liquid-liquid phase separation driven by a serine-rich C-terminal region and impaired by neurodevelopmental disease-related truncations
Lrif1调节Trim28介导的小鼠胚胎干细胞中Dux位点的抑制作用	Sikrova, D.	PDF	N/A	Lrif1 modulates Trim28-mediated repression of the Dux locus in mouse embryonic stem cells
完整氨酰化tRNA的纳米孔测序	White, L. K.	PDF	N/A	Nanopore sequencing of intact aminoacylated tRNAs
渗透压膨胀的囊泡而非中间丝上的NLRP3支架促进了炎症小体的组装	de Paz Linares, G. A.	PDF	N/A	Scaffolding of NLRP3 on osmotically swollen vesicles but not intermediate filaments promotes inflammasome assembly
地球历史上固氮酶结构的演变	Cuevas, B.	PDF	N/A	Nitrogenase structural evolution across Earth s history
一种用于在真菌性脑膜炎病原体新生隐球菌中进行条件性突变的生长素诱导降解系统	Madhani, H. D.	PDF	N/A	An auxin-inducible degron system for conditional mutation in the fungal meningitis pathogen Cryptococcus neoformans
通过原位多聚腺苷酸化和空间RNA测序实现微生物群-宿主相互作用的高分辨率空间映射	Ntekas, I.	PDF	N/A	High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing
野生型和FMR1敲除的人类胚胎干细胞中核糖体的分析	Kharbanda, T.	PDF	N/A	Analysis of ribosomes from the Wild-type and FMR1 knockout human embryonic stem cells
3-甲基胞嘧啶修饰对神经元富集的精氨酸tRNA反密码子茎的结构影响	Berger, K.	PDF	N/A	Structural impact of 3-methylcytosine modification on the anticodon stem of a neuronally-enriched arginine tRNA
使用深度学习进行高亲和力蛋白质结合大环的精确从头设计	Rettie, S.	PDF	N/A	Accurate de novo design of high-affinity protein binding macrocycles using deep learning
无参考分析单细胞RNA测序数据揭示了在蝾螈神经发生过程中rRNA和mtRNA转录的升高	Ratul, M. R. Z.	PDF	N/A	Reference-free Analysis of scRNA-seq Data Reveals Elevated rRNA and mtRNA Transcription during Neurogenesis in Axolotl
高通量筛选揭示针对肺炎克雷伯菌和大肠杆菌中抗甲氧苄啶的DfrA1蛋白的潜在抑制剂	Hasnat, S.	PDF	N/A	High-Throughput Screening Reveals Potential Inhibitors Targeting Trimethoprim-Resistant DfrA1 Protein in Klebsiella pneumoniae and Escherichia coli
Sphae：一种从测序数据中自动预测噬菌体疗法候选者的工具包	Papudeshi, B.	PDF	N/A	Sphae: An automated toolkit for predicting phage therapy candidates from sequencing data
军团菌肺炎杆菌对单一和多宿主的宿主特异性适应	Moreno, A. B.	PDF	N/A	Host-specific adaptation of Legionella pneumophila to single and multiple hosts
回到角的问题：通过不同类型的重组事件对祖先角状态的重建。	Upadhyay, M.	PDF	N/A	Back to the horns: a reconstruction of the ancestral horn state through distinct types of recombination events.
用于蛋白质组数据质询的归一化与方向性相互作用评分	Poncha, K. F.	PDF	N/A	Normalized and Directional Interplay Scoring for the Interrogation of Proteoform Data
TAP2蛋白变异体的鉴定，这些变异体对HSV1 ICP47蛋白的抑制具有抗性	Nagy, G.	PDF	N/A	Identification of TAP2 protein variants resistant to inhibition by the HSV1 ICP47 protein
生物膜生活方式作为氨氧化古菌的共同特征	Dreer, M.	PDF	N/A	Biofilm lifestyle as a common trait of ammonia-oxidizing archaea
# BioRxiv 2024-11-17 Papers

标题	作者	PDF链接	代码仓库	Title
贝叶斯球：贝叶斯方法在职业棒球击球员中的整合	Brantley, J. A.	PDF	N/A	Bayesball: Bayesian Integration in Professional Baseball Batters
p53翻译异构体Δ40p53通过调节miR-4671-5p/SGSH轴调控细胞周期	Pal, A.	PDF	N/A	p53 translational-isoform Δ 40p53 regulates cell cycle by modulating the miR-4671-5p/SGSH axis
古代和现代伊比利亚牛的基因组中留下了野牛杂交的遗传遗产	Günther, T.	PDF	N/A	The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle
一种富含棕色脂肪的脂肪因子，ASRA，是一种瘦素受体拮抗剂，能够刺激食欲。	Huang, L.	PDF	N/A	A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite
使用变分自编码器实现AI设计的基因组	Dudek, N. K.	PDF	N/A	Towards AI-designed genomes using a variational autoencoder
通过集体迁徙实现的非遗传性适应	Vo, L.	PDF	N/A	Non-genetic adaptation by collective migration
人类强化学习中对缓慢变化特征的归纳偏置	Hedrich, N. L.	PDF	N/A	An inductive bias for slowly changing features in human reinforcement learning
全脑血流动力学预测人类在睡眠和清醒状态下的神经节律	Jacob, L. P. L.	PDF	N/A	Brainwide hemodynamics predict neural rhythms across sleep and wakefulness in humans
定量超微结构时间线揭示了自噬在细胞核中的作用，并揭示了动力蛋白样蛋白1在核膜中的作用	Mannino, P. J.	PDF	N/A	A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope
调控性ChREBP/14-3-3复合物的分子胶保护β细胞免受糖脂毒性影响。	Katz, L. S.	PDF	N/A	Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.
肾小球弹性与基因表达模式定义了Alport肾病的两个阶段	Yoon, J.	PDF	N/A	Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
BAITSAO：基于语言模型的药物协同分析基础模型构建	Liu, T.	PDF	N/A	BAITSAO: Building A Foundation Model for Drug Synergy Analysis Powered by Language Models
在不同黄鲈（Perca flavescens）种群中，有效种群大小变化背景下发生的平行遗传适应	Yin, X.	PDF	N/A	Parallel genetic adaptation amidst a background of changing effective population sizes in divergent yellow perch (Perca flavescens) populations
心灵字幕：从人脑活动中演化出心理内容的描述性文本	Horikawa, T.	PDF	N/A	Mind Captioning: Evolving descriptive text of mental content from human brain activity
导致精神病的损伤在大脑海马中映射到一条共同的脑回路	Pines, A. R.	PDF	N/A	Lesions that Cause Psychosis Map to a Common Brain Circuit in the Hippocampus
静水压力与肌动蛋白聚合的联合作用驱动内皮尖端细胞迁移和发芽血管生成	Kondrychyn, I.	PDF	N/A	Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis
基于CRISPRi的微胶质细胞自闭症谱系障碍风险基因筛选揭示了ADNP在微胶质细胞内吞作用和突触修剪中的作用	Teter, O. M.	PDF	N/A	CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning
微生物间的相互作用影响抗生素抗性演化的速度和模式。	Zandbergen, L. E.	PDF	N/A	Microbial interactions affect the tempo and mode of antibiotic resistance evolution
理解深度药物反应模型性能的来源揭示了见解和改进	Branson, N.	PDF	N/A	Understanding the Sources of Performance in Deep Drug Response Models Reveals Insights and Improvements
在高分辨率和高准确度下对听觉中脑的神经编码进行建模	Drakopoulos, F.	PDF	N/A	Modeling neural coding in the auditory midbrain with high resolution and accuracy
探究自然脑动力学拓扑结构中的个体差异	Xian, J.	PDF	N/A	Probing Individual Differences in the Topological Landscape of Naturalistic Brain Dynamics
乙烯受体获得和丧失功能突变体揭示了根中依赖于ETR1的转录网络	Khoury, M. G.	PDF	N/A	Ethylene Receptor Gain- and Loss-of-function Mutants Reveal an ETR1-dependent Transcriptional Network in Roots
一种高效预测自然物体感知相似性的高通量方法	Kaniuth, P.	PDF	N/A	A high-throughput approach for the efficient prediction of perceived similarity of natural objects
在异源二倍体和四倍体种群中，基因组预测杂种优势、近交控制和配对分配	Endelman, J. B.	PDF	N/A	Genomic prediction of heterosis, inbreeding control, and mate allocation in outbred diploid and tetraploid populations
活性树突化学突触与间隙连接的细胞外信号之间的二分法	Sirmaur, R.	PDF	N/A	Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions
突触前囊泡循环中的幂律适应	Mikulasch, F. A.	PDF	N/A	Power-law adaptation in the presynaptic vesicle cycle
重复激活视前区接收神经元在室旁核后部介导慢性热诱导的负性情绪效价和过度唤醒状态	Cao, Z.	PDF	N/A	Repeated activation of preoptic area-recipient neurons in posterior paraventricular nucleus mediates chronic heat-induced negative emotional valence and hyperarousal states
交配系统对多个属中谱系分化的影响分析	Xu, K.	PDF	N/A	Analysis of the effects of mating systems on lineage diversification across multiple genera
用于多胺的基因编码荧光报告器	Sharma, P.	PDF	N/A	Genetically encoded fluorescent reporter for polyamines
主要抑郁症的基因年龄差距估计（GAGE）：使用基因表达的惩罚性生物年龄模型	Li, Y.	PDF	N/A	Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression
在肿瘤发生过程中，mRNA的等位基因失衡被选择性地保留，这一现象源于表观遗传的改变，并且与预后相关。	Palou-Marquez, G.	PDF	N/A	Allele imbalance in mRNA is selected in tumorigenesis, results from epigenetic alterations and has prognostic relevance
横断面脑龄评估在预测未来脑变化方面存在局限性。	Korbmacher, M.	PDF	N/A	Cross-sectional brain age assessments are limited in predicting future brain change
通过基因组和线粒体数据揭示的濒危物种西伯利亚鼯鼠（Pteromys volans）的种群结构	Ito dos Santos, F.	PDF	N/A	Population structure of the endangered Siberian flying squirrel (Pteromys volans) revealed by genomic and mitochondrial data
弥合秀丽隐杆线虫的连接组与全脑活动之间的差距	Creamer, M. S.	PDF	N/A	Bridging the gap between the connectome and whole-brain activity in C. elegans
过滤点过程可有效捕捉神经电生理记录中的节奏性和宽带功率谱结构	Bloniasz, P. F.	PDF	N/A	Filtered Point Processes Tractably Capture Rhythmic And Broadband Power Spectral Structure in Neural Electrophysiological Recordings
利用光谱流式细胞术对全细胞中核组蛋白H3的翻译后修饰进行分析	Golden, C. S.	PDF	N/A	Nuclear Histone H3 Post-translational Modification Profiling in Whole Cells using Spectral Flow Cytometry
通过拓扑高阶功能连接解析精神分裂症中的整合-分离失衡	Li, Q.	PDF	N/A	Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity
ASCL1介导的染色质结合和基因激活的增殖性与神经元程序具有细胞周期阶段特异性	Beckman, W. F.	PDF	N/A	Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific
LipiDetective - 一种用于在串联质谱中识别分子脂质种类的深度学习模型	Wuerf, V.	PDF	N/A	LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra
代谢物营养图谱指南（MeNu GUIDE）——一种用于揭示与疾病病因相互作用的代谢物营养图谱	Wuerf, V.	PDF	N/A	MeNu GUIDE - a metabolite nutrition graph to uncover interactions with disease etiology
sv-channels：使用一维卷积神经网络过滤基因组删除	Santuari, L.	PDF	N/A	sv-channels: filtering genomic deletions using one-dimensional convolutional neural networks
节奏与背景（RnB）：睡眠记录的光谱分析	Dube, J.	PDF	N/A	Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings
利用语言引导的视觉模型进行空间蛋白质组学的广义细胞表型分析	Wang, X.	PDF	N/A	Generalized cell phenotyping for spatial proteomics with language-informed vision models
较长的内含子往往含有更多的串联重复序列，并且更频繁地经历插入和删除，这些插入和删除大多发生在编码蛋白质的内在无序区域。	Homma, K.	PDF	N/A	Longer internal exons tend to have more tandem repeats and more frequently experience insertions and deletions that are mostly in intrinsically disordered regions of the encoded proteins
长期服用裸盖菇素对前额-纹状体-丘脑回路动态性和有效性连接的影响	Pasquini, L.	PDF	N/A	Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits
减少功能缺陷的老化造血干细胞（HSCs）可减轻老年受体小鼠的衰老相关表型	Wang, Y.	PDF	N/A	Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice
从人类诱导多能干细胞（iPSCs）生成形态上不同的星形胶质细胞亚型揭示了胶质形态、功能和反应性之间的联系	O'Toole, K.	PDF	N/A	Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity
核糖体丰度而非同源基因组成对于生殖系发育至关重要	Grobicki, K. Z. A.	PDF	N/A	Ribosome abundance, not paralogue composition, is essential for germline development
CPSM：用于预测单个癌症患者生存概率的自动化机器学习管道R包	Kaur, H.	PDF	N/A	CPSM: R-package of an Automated Machine Learning Pipeline for Predicting the Survival Probability of Single Cancer Patient
上游开放阅读框在果蝇进化和发育过程中缓冲翻译变异性	Sun, Y.	PDF	N/A	Upstream open reading frames buffer translational variability during Drosophila evolution and development
AlphaRING: 通过蛋白质建模和残基相互作用网络分析进行错义变异分类	Logsdon, A.	PDF	N/A	AlphaRING: Missense Variant Classification via Protein Modelling and Residue Interaction Network Analysis
首次为三种海葵（珊瑚纲：海葵目）宿主物种生成了从头组装的HiFi基因组	De Jode, A.	PDF	N/A	The first de novo HiFi genome assemblies for three clownfish-hosting sea anemone species (Anthozoa: Actiniaria)
从Hi-C数据解读跨物种的3D基因组结构	Shkolikov, A.	PDF	N/A	Deciphering the 3D genome organization across species from Hi-C data
雪貂乳腺内感染牛H5N1流感病毒导致哺乳期新生儿传播和死亡	Baker, P. H.	PDF	N/A	Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission and mortality in suckling neonates
在肠道微生物群中，通过衣壳介导的大规模细菌基因组DNA的移动	Borodovich, T.	PDF	N/A	Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
人类中枢神经系统中的体感高频振荡	Bailey, E.	PDF	N/A	Somatosensory high frequency oscillations across the human central nervous system
很少是绝对的，总是高维的：神经代码如何随着皮层层次的变化而变化	Posani, L.	PDF	N/A	Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy
产后中缝背侧核对脊髓内侧深背侧角RORβ中间神经元的5-羟色胺调节的成熟过程	West, C. W.	PDF	N/A	Postnatal maturation of serotonergic modulation of spinal RORβ interneurons in the medial deep dorsal horn
揭示动态人脑相位一致性网络	Olsen, A. S.	PDF	N/A	Uncovering dynamic human brain phase coherence networks
一种基于视紫红质的新型电压指示剂，用于在体内同时进行双光子光学记录与GCaMP	Villette, V.	PDF	N/A	A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo
Gria3突变小鼠（一种精神分裂症的遗传动物模型）中脑区特异性改变及活动调节基因的失调	Huang, W.-C.	PDF	N/A	Brain-region-specific changes and dysregulation of activity regulated genes in Gria3 mutant mice, a genetic animal model of schizophrenia
终纹床核的促肾上腺皮质激素释放因子神经元在性别和动情周期阶段上表现出依赖性的突触活动差异，以及在焦虑增强的惊跳反应中的作用差异。	Chudoba, R.	PDF	N/A	Corticotropin-releasing factor neurons of the bed nucleus of the stria terminalis demonstrate sex- and estrous phase-dependent differences in synaptic activity and in their role in anxiety-potentiated startle
淀粉样β寡聚体引起的社交和情境记忆障碍通过Sigma-1受体激活得以恢复	Djebari, S.	PDF	N/A	Social and Contextual Memory Impairments Induced by Amyloid-β Oligomers are Rescued by Sigma-1 Receptor Activation
单个神经元对特定模态和非模态语言的处理	Yair, L.	PDF	N/A	Modality-Specific and Amodal Language Processing by Single Neurons
激活下丘脑-脑桥-脊髓通路促进小鼠脊髓损伤后的运动启动和功能恢复	Li, Y.	PDF	N/A	Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice
外侧下丘脑中的皮层输入整合主要由内侧前额叶皮层主导。	Razenberg, L. J. A. M.	PDF	N/A	Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex
时钟基因period和timeless控制果蝇运动终末的突触发生	Ferreiro, M. J.	PDF	N/A	Clock genes period and timeless control synaptogenesis in Drosophila motor terminals
在人类真菌病原体的形态发生过程中，细胞质的动态流动性	Serrano, A.	PDF	N/A	Dynamic cytoplasmic fluidity during morphogenesis in a human fungal pathogen
使用无基因模型对发育细胞命运转变进行定量引导	Hajji, I.	PDF	N/A	Quantitative guiding of developmental cell fate transitions using gene-free modelling
早期运动干扰了斑马鱼鳍再生过程中促进修复的细胞外基质程序	Lewis, V. M.	PDF	N/A	Early exercise disrupts a pro-repair extracellular matrix program during zebrafish fin regeneration
人类滋养层干细胞和胎盘中的染色体不稳定性	Wang, D.	PDF	N/A	Chromosomal Instability in Human Trophoblast Stem Cells and Placentas
在一种模型刺胞动物-藻类共生关系中，若缺乏异养性摄食，无性后代发育过程中共生关系会瓦解。	Bedgood, S. A.	PDF	N/A	Symbiosis collapses during development of asexual offspring in the absence of heterotrophic feeding in a model cnidarian-algal symbiosis
通过四种方案在类器官中重建人类脑细胞多样性	Naas, J.	PDF	N/A	Reconstitution of Human Brain Cell Diversity in Organoids via Four Protocols
无偏倚的多能性景观分析揭示了克隆命运偏倚的空间调节因子	Erickson, A. G.	PDF	N/A	Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases
无偏倚的多能性景观分析揭示了克隆命运偏倚的空间调节因子	Erickson, A. G.	PDF	N/A	Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases
全脑因果连接在解码神经反馈中的作用：一项元研究	Arab, F.	PDF	N/A	Whole-brain causal connectivity during decoded neurofeedback: a meta study
使用可穿戴设备信号的婴幼儿自动持续注意力预测方法，尽快完成翻译。	Zhang, Y.	PDF	N/A	ASAP: An automatic sustained attention prediction method for infants and toddlers using wearable device signals
结合神经绘画与转录组学揭示22q11.2缺失的细胞类型特异性形态和分子特征	Tegtmeyer, M.	PDF	N/A	Combining NeuroPainting with transcriptomics reveals cell-type-specific morphological and molecular signatures of the 22q11.2 deletion
右侧后部θ波反映了在目标导向导航过程中，人类海马旁区因显著线索而发生的相位重置。	Güth, M. R.	PDF	N/A	Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
热休克因子1调控跨物种的睡眠-觉醒周期	Yamazaki, S.	PDF	N/A	Heat Shock Factor 1 Governs Sleep-Wake Cycles Across Species
在PS19小鼠中上调ANKHD1表达可减少Tau蛋白磷酸化，并缓解Tau毒性引起的认知功能障碍。	Tian, X.	PDF	N/A	Upregulating ANKHD1 in PS19 mice reduces Tau phosphorylation and mitigates Tau-toxicity-induced cognitive deficits
无意识和有意识视觉处理的神经相关性	Menetrey, M. Q.	PDF	N/A	Neural correlates of unconscious and conscious visual processing
小脑白质发育受依赖于fractalkine的小胶质细胞对少突胶质前体细胞的吞噬作用调控。	Chappell, M. K.	PDF	N/A	Cerebellar white matter development is regulated by fractalkine-dependent microglia phagocytosis of oligodendrocyte progenitor cells
可以高效地从牛胚胎发育的不同阶段获得原始牛胚胎干细胞系，并且这些细胞系具有相似的分子特征。	Guiltinan, C.	PDF	N/A	Primed bovine embryonic stem cell lines can be derived at diverse stages of blastocyst development with similar efficiency and molecular characteristics
保守的蚜虫唾液化学感觉蛋白效应子Mp10通过靶向植物细胞膜上的AMSH去泛素化酶来抑制模式触发的免疫	Gravino, M.	PDF	N/A	The conserved aphid saliva chemosensory protein effector Mp10 targets plant AMSH deubiquitinases at cellular membranes to suppress pattern-triggered immunity
TaMYB7-A1的自然变异调控小麦对PHS的抗性并特化其地理适应性	Wang, H.	PDF	N/A	Natural variations of TaMYB7-A1 regulate PHS resistance and specify wheat geographic adaptation
增强型肠道上皮共培养模型与轨道机械刺激：在食品纳米毒理学中的概念验证应用	Santoni, M.	PDF	N/A	Enhanced Intestinal Epithelial Co-Culture Model with Orbital Mechanical Stimulation: A Proof-of-Concept Application in Food Nanotoxicology
比较功能性磁共振成像揭示了狗和人类在视觉皮层功能组织上对于生命感知存在的差异	Farkas, E. B.	PDF	N/A	Comparative fMRI reveals differences in the functional organization of the visual cortex for animacy perception in dogs and humans
转译抑制剂与铜离子协同作用，增强抗生素活性	Vazquez-Hernandez, M.	PDF	N/A	Trans-Translation inhibitors and copper ions synergize for enhanced antibiotic activity
糖磷酸介导的肽聚糖前体合成抑制	Keller, M. R.	PDF	N/A	Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis
用于开发靶向IPNv VP2蛋白纳米抗体的小说库组装技术	Pino-Belmar, C.	PDF	N/A	Novel Library Assembly Technique for Developing Nanobodies Targeting IPNv VP2 Protein
SAM转甲基化途径和腺苷再循环生成ATP对于系统性调节和免疫反应至关重要。	Nedbalova, P.	PDF	N/A	SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response
温度和溶解有机物塑造了亚北极海中海洋原核生物的活动和基因表达	Amnebrink, D.	PDF	N/A	Temperature and dissolved organic matter shape marine prokaryotic activity and gene expression in a sub-arctic sea
AACDB：抗原-抗体复合物数据库——一个全面的数据库，揭示相互作用界面的洞察力	Zhou, Y.	PDF	N/A	AACDB: Antigen-Antibody Complex Database -- a Comprehensive Database Unlocking Insights into Interaction Interface
视觉训练诱导的人类枕叶快速睡眠纺锤体聚集现象通过全夜高清脑电图记录揭示	Gervan, P.	PDF	N/A	Visual training induced occipital fast sleep spindle clustering in humans revealed by full-night HD-EEG recordings
通过昼夜节律转录因子NPAS2调节雄性和雌性小鼠中的芬太尼奖赏机制	Barko, K.	PDF	N/A	Regulation of Fentanyl Reward in Male and Female Mice by the Circadian Transcription Factor NPAS2
任务期间个体大脑活动模式由不同的静息态网络预测，这些网络可能反映了局部神经生物学特征。	Scholz, R.	PDF	N/A	Individual brain activity patterns during task are predicted by distinct resting-state networks that may reflect local neurobiological features
前运动核HVC中神经活动的时间和刻板序列传播的生物物理网络建模	Diab, Z. B.	PDF	N/A	Biophysical network modeling of temporal and stereotyped sequence propagation of neural activity in the premotor nucleus HVC
AcrVIB1通过促进无功能的crRNA结合，使其易受RNase攻击，从而抑制CRISPR-Cas13b免疫。	Wandera, K. G.	PDF	N/A	AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack
快速行进至分支形态	Kriuchechnikova, A. N.	PDF	N/A	Fast marching to branching morphologies
CB1和CB2受体在调节母体免疫激活和围产期大麻素暴露对认知影响的方面表现出差异性作用。	Mackie, K.	PDF	N/A	CB1 and CB2 receptors differentially modulate the cognitive impact of maternal immune activation and perinatal cannabinoid exposure
连接图谱和基于扰动的敏感性分析识别出MEK抑制剂作为人类肺成纤维细胞中的衰老抑制剂	Nayeri Rad, A.	PDF	N/A	Connectivity Map and perturbation-based sensitivity analysis identifies MEK inhibitors as senolytics in human lung fibroblasts
尖生长细胞的形态动力学	Jones, G. W.	PDF	N/A	Morphodynamics of tip growing cells
热激触发的小孢子转录重编程破坏了甘蓝型油菜花粉发育进程	Lohani, N.	PDF	N/A	Heat-Triggered Transcriptional Reprogramming in Microspores Disrupts Progression of Pollen Development in Brassica napus L.
靶向DNA ADP-核糖基化在细菌中触发模板修复，在真核生物中引发碱基突变	Patinios, C.	PDF	N/A	Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes
荧光假单胞菌中遗传电路的动力学	Rico, J.	PDF	N/A	Dynamics of genetic circuits in Pseudomonas protegens
谷氨酸受体依赖的海马神经元细胞质酸化涉及从细胞外空间被动流入的质子。	Pedersen, S. E.	PDF	N/A	Glutamate receptor-dependent cytosolic acidification in hippocampal neurons involves passive flux of protons from the extracellular space
干扰素Epsilon通过自分泌的细胞内信号传导保护上皮屏障免受病毒感染	Casazza, R. L.	PDF	N/A	Interferon Epsilon Protects Epithelial Barriers from Viral Infection through Autocrine Intracellular Signaling
鉴定调控食道过敏性炎症的神经免疫回路	Kellerman, K.	PDF	N/A	Identification of a Neuroimmune Circuit that Regulates Allergic Inflammation in the Esophagus
IL-33通过恢复体液免疫来预防复发性艰难梭菌感染。	naz, f.	PDF	N/A	IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity
通过成像质谱流式细胞术对细胞外基质进行表型分析，确定了与过敏性气道炎症相关的不同细胞外基质环境。	Parkinson, J. E.	PDF	N/A	Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation.
一种伴有婴儿肠结肠炎的自发性炎症动物模型	Kang, Z.	PDF	N/A	An animal model for autoinflammation with infantile enterocolitis
鼻病毒作为严重哮喘儿童气道T细胞动态的驱动因素	Bryant, N.	PDF	N/A	Rhinovirus as a Driver of Airway T-Cell Dynamics in Children with Severe Asthma
肠道细菌Bacteroidales的适应性变化有助于其与溶菌性噬菌体的稳定共存。	Cortes-Martin, A.	PDF	N/A	Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages
尼日利亚夸拉州伊洛林大都会区养殖鱼类中迟缓爱德华菌的抗菌敏感性特征	OLABISI, F. O.	PDF	N/A	ANTIMICROBIAL SUSCEPTIBILITY PROFILE OF Edwardsiella tarda FROM FARMED FISH IN ILORIN METROPOLIS, KWARA STATE NIGERIA
有益细菌枯草芽孢杆菌（B. subtilis）的生物膜和浮游细胞在应对原生动物捕食者痢疾内变形虫（Entamoeba histolytica）时采用的不同应对策略。	Kolodkin-Gal, I.	PDF	N/A	Differential coping strategies exerted by biofilm and planktonic cells of the beneficial bacterium B. subtilis in response to the protozoan predator Entamoeba histolytica.
博茨瓦纳、加蓬、肯尼亚、南非和美国非洲象体内潜伏的象内皮嗜性疱疹病毒和象伽玛疱疹病毒感染情况	Pearson, V. R.	PDF	N/A	Quiescent Infections of Elephant Endotheliotropic Herpesviruses and Elephant Gammaherpesviruses in African Elephants in Botswana, Gabon, Kenya, South Africa and USA
猎物移动影响虚拟二营养级系统中捕食者专业技能的获取	Fraser Franco, M.	PDF	N/A	Prey movement shapes the acquisition of predator expertise in a virtual bi-trophic system
在具有角色间速率变化的Mkv模型上	Capobianco, A.	PDF	N/A	On the Mkv Model with Among-Character Rate Variation
尼莫知道：小丑鱼能够区分细小和广阔地理尺度上的隐秘宿主物种，并揭示了小丑鱼与其宿主海葵之间潜在的适应性辐射。	Chiodo, T.	PDF	N/A	Nemo knows: clownfishes differentiate cryptic host species across fine and broad geographic scales and reveal a potential adaptive radiation in the clownfish-hosting sea anemones.
非洲无花果蝇（Zaprionus indianus）在温带地区定居后翅膀尺寸的快速进化	Gray, W. J.	PDF	N/A	Rapid wing size evolution in African fig flies (Zaprionus indianus) following temperate colonization
HSP90 缓冲了 BRCA1 中的有害遗传变异	Gracia, B.	PDF	N/A	HSP90 buffers deleterious genetic variations in BRCA1
GWAC：一种在数据受限物种中识别功能变异的机器学习方法	Sharo, A. G.	PDF	N/A	GWAC: A machine learning method to identify functional variants in data-constrained species
用于多组学分析样品制备的单个微流控装置	Ravi Kumar, R. K.	PDF	N/A	A single microfluidic device for multi-omics analysis sample preparation
在微流控人体皮肤等效物中以单细胞分辨率复制动态免疫反应	Hindle, S. A.	PDF	N/A	Replicating dynamic immune responses at single-cell resolution within a microfluidic human skin equivalent
基于结构的模拟的前瞻性评估揭示了其预测激酶突变对抑制剂结合影响的能力	Singh, S.	PDF	N/A	Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding
OncotreeVIS - 一种用于可视化突变树队列的交互式图形用户界面	Baciu-Dragan, M. A.	PDF	N/A	OncotreeVIS - an interactive graphical user interface for visualizing mutation tree cohorts
靶向TEAD的小分子通过诱导辅因子转换来调节Hippo通路	Guarnaccia, A. D.	PDF	N/A	TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway
单细胞分辨率的空间分析：抗原呈递型癌症相关成纤维细胞微环境的解析	Chen, X.	PDF	N/A	Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches
鉴定MRTFA/SRF通路作为癌症中静止状态的关键调节因子。	Panesso-Gomez, S.	PDF	N/A	Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer.
池塘和池塘养殖的吉富罗非鱼微生物组动态	Delamare-Deboutteville, J.	PDF	N/A	Microbiome Dynamics in Tank- and Pond-Reared GIFT Tilapia
染色体工程恢复含有复杂染色体8重排的细胞的整倍性	Lee, S. N.	PDF	N/A	Chromosome engineering to restore euploidy in cells harboring a complex rearrangement of chromosome 8
西部斜坡割喉鳟（Oncorhynchus lewisi）的基因组组装揭示了其与虹鳟之间存在种间染色体重排。	Flores, A.-M.	PDF	N/A	The genome assembly of the westslope cutthroat trout, Oncorhynchus lewisi, reveals interspecific chromosomal rearrangements with the rainbow trout
PanTax：利用泛基因组图谱对宏基因组数据进行菌株水平分类	Zhang, W.	PDF	N/A	PanTax: Strain-level taxonomic classification of metagenomic data using pangenome graphs
CellPatch：一种高效的基础模型，用于单细胞转录组学，采用启发式补丁方法	Wu, H.-J.	PDF	N/A	CellPatch: a Highly Efficient Foundation Model for Single-Cell Transcriptomics with Heuristic Patching
滤泡性淋巴瘤和慢性淋巴细胞白血病在单细胞分辨率下的增殖微环境	Ferreira, A. P.	PDF	N/A	The follicular lymphoma and chronic lymphocytic leukemia proliferative microenvironment at single-cell resolution
跨组织图注意力网络用于半监督基因表达预测	Wang, S.	PDF	N/A	Cross-tissue Graph Attention Networks for Semi-supervised Gene Expression Prediction
基于神经形态成像的人血细胞计数法	Zhang, Z.	PDF	N/A	Neuromorphic Imaging Cytometry on Human Blood Cells
# BioRxiv 2024-11-16 Papers

标题	作者	PDF链接	代码仓库	Title
瘤胃微生物群中的抗病毒防御系统	Saenz, J. S.	PDF	N/A	Antiviral defence systems in the rumen microbiome
LIMPACAT：利用全切片成像的肝癌免疫预测多组学注意力变压器	Chiu, Y. J.	PDF	N/A	LIMPACAT : Multi-Omics Attention Transformer for Immune Prediction in Liver Cancer Using Whole-Slide Imaging
对紫杉树进行多重扰动揭示了隐藏的蛋白质，这些蛋白质能够实现巴卡亭III和紫杉醇前体的全生物合成。	McClune, C. J.	PDF	N/A	Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors
从单细胞数据中推断细胞类型特异性的共表达基因	Shan, X.	PDF	N/A	Inferring Cell-Type-Specific Co-Expressed Genes from Single Cell Data
用于植物基因组大小估计的流式细胞仪标准的重新校准	Soni, A.	PDF	N/A	Re-calibration of flow cytometry standards for plant genome size estimation
海洛因和甲基苯丙胺戒断患者的大脑形态学改变及大脑网络形态学紊乱	Zhou, X.	PDF	N/A	Morphological brain alterations and morphological brain network disorganizations in heroin and methamphetamine abstinent patients
可卡因使用障碍中的功能连接改变：三重网络模型和成瘾神经临床评估框架的见解	Xu, Z.	PDF	N/A	Functional Connectivity Alterations in Cocaine Use Disorder: Insights from the Triple Network Model and the Addictions Neuroclinical Assessment Framework
注意依赖的属性比较是眶额皮层中多属性决策的基础	Perkins, A. Q.	PDF	N/A	Attention-dependent attribute comparisons underlie multi-attribute decision-making in orbitofrontal cortex
Sortilin C末端片段沉积描绘了阿尔茨海默病中与缠结相关的非淀粉样神经炎斑块的生长	Zhang, Q.-L.	PDF	N/A	Sortilin C-terminal fragment deposition depicts tangle-related nonamyloid neuritic plaque growth in Alzheimers disease
WMH-DualTasker：一种具有自监督一致性的双任务深度学习模型，用于白质高信号的自动分割与视觉评分——一项多中心研究	Wu, Y.	PDF	N/A	WMH-DualTasker: A Dual-Task Deep Learning Model with Self-supervised Consistency for Automated Segmentation and Visual Rating of White matter Hyperintensities - a Multicentre study
I型干扰素信号增强卡因酸诱导的癫痫严重程度	Ma, J.-H.	PDF	N/A	Type I interferon signaling enhances kainic acid-induced seizure severity
小鼠的热适应需要视前区BDNF神经元及突触后增强作用	Chen, B.	PDF	N/A	Heat Acclimation in Mice Requires Preoptic BDNF Neurons and Postsynaptic Potentiation
化学遗传学破坏齿状门导致癫痫和空间记忆缺陷	Adam, C. D.	PDF	N/A	Chemogenetic Breakdown of the Dentate Gate Causes Seizures and Spatial Memory Deficits
青少年高脂饮食和心理社会压力对成年雄性Lewis大鼠神经内分泌应激反应及暴食行为的影响	Sierra, J.	PDF	N/A	Impact of adolescent high-fat diet and psychosocial stress on neuroendocrine stress responses and binge eating behavior in adult male Lewis rats
PrP 在体内的周转以及朊病毒疾病治疗药物起效的时间	Corridon, T. L.	PDF	N/A	PrP turnover in vivo and the time to effect of prion disease therapeutics
慢性病毒再激活及其相关宿主免疫反应和急性COVID-19及COVID-19后遗症的临床结果	Maguire, C.	PDF	N/A	Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19
通过多样性生成逆转录元件在肠道微生物组中进行靶向蛋白质进化	Macadangdang, B. R.	PDF	N/A	Targeted protein evolution in the gut microbiome by diversity-generating retroelements
海洋细菌群落中出乎意料的高水平抗生素抗性无法仅通过城市河流排放来解释	Chan, B. W.	PDF	N/A	Unexpected levels of antibiotic resistance in marine bacterial communities not solely explained by urban river discharge
牛H5N1流感病毒感染通过乳汁传播，导致哺乳期新生儿的死亡。	Baker, P. H.	PDF	N/A	Bovine H5N1 influenza virus infection is transmitted by milk causing mortality in suckling neonates
加纳热带稀树草原地区牛群中Q热传播的动态分析。	Otoo, D.	PDF	N/A	Dynamic analysis of Q-fever transmission among cattle in the Tropical Savannah Grassland zone of Ghana.
Arv1与并调控念珠菌GPI生物合成的第一步相互作用	Komath, S. S.	PDF	N/A	Arv1 interacts with and regulates the first step of GPI biosynthesis in Candida albicans
源自副干酪乳杆菌CNCM I-5220的后生元可缓解皮肤炎症并保护皮肤屏障完整性。	Pimazzoni, S.	PDF	N/A	Lactobacillus paracasei CNCM I-5220-derived postbiotic counteracts skin inflammation and protects skin barrier integrity
利用深度学习在古菌组中发现的抗生素	Torres, M. D. T.	PDF	N/A	Discovery of antibiotics in the archaeome using deep learning
从囊性纤维化呼吸系统感染中分离的金黄色葡萄球菌种群的种内多样性	Alexander, A. M.	PDF	N/A	Intraspecific Diversity of Staphylococcus aureus Populations Isolated from Cystic Fibrosis Respiratory Infections
布鲁氏菌感染小鼠组织代谢组学分析	Ponzilacqua-Silva, B.	PDF	N/A	Metabolomic Analysis of Murine Tissues Infected with Brucella melitensis
奥罗波奇病毒感染人胎盘外植体和滋养层类器官	Megli, C.	PDF	N/A	Oropouche virus infects human placenta explants and trophoblast organoids
绘制人类肠道细菌中农药诱导的代谢变化图谱	Chen, L.	PDF	N/A	Mapping Pesticide-Induced Metabolic Alterations in Human Gut Bacteria
线粒体甲基化潜能调控线粒体核糖体组装	Glasgow, R. I. C.	PDF	N/A	The mitochondrial methylation potential gates mitoribosome assembly
miRNA在果蝇中靶向作用的生化原理	Vega-Badillo, J.	PDF	N/A	Biochemical principles of miRNA targeting in flies
以植物为基础的疫苗接种表达弓形虫SAG1与植物HSP90融合蛋白在羔羊中引发保护性免疫反应	Campero, L. M.	PDF	N/A	Immunization with Plant-based Vaccine Expressing Toxoplasma gondii SAG1 Fused to Plant HSP90 Elicits Protective Immune Response in Lambs
促进解离设计使得对细胞因子信号持续时间的控制成为可能	Broerman, A. J.	PDF	N/A	Design of facilitated dissociation enables control over cytokine signaling duration
将选择性紫色杆菌素途径酶封装在1,2-丙二醇利用细菌微区室中以转移途径通量	Palmero, B. J.	PDF	N/A	Encapsulation of Select Violacein Pathway Enzymes in the 1,2-Propanediol Utilization Bacterial Microcompartment to Divert Pathway Flux
在肠道微生物群中，通过衣壳介导的大规模细菌基因组DNA的移动	Borodovich, T.	PDF	N/A	Large scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome
在灌丛和林地生境中，野火后土壤病毒和原核生物群落发生了显著变化。	Geonczy, S.	PDF	N/A	Soil viral and prokaryotic communities shifted significantly after wildfire in chaparral and woodland habitats
氨氧化菌对深海无机碳固定的贡献	Bayer, B.	PDF	N/A	Contribution of ammonia oxidizers to inorganic carbon fixation in the dark ocean
发酵白菜代谢组及其对Caco-2单层细胞因诱导的肠道屏障破坏的保护作用	Marco, M. L.	PDF	N/A	The fermented cabbage metabolome and its protection against cytokine-induced intestinal barrier disruption of Caco-2 monolayers
钙调蛋白在Kv7.2通道钙响应域的共翻译折叠过程中充当伴侣蛋白。	Muguruza-Montero, A.	PDF	N/A	Calmodulin acts as a chaperone during co-translational folding of the Kv7.2 channel Calcium Responsive Domain.
利托那韦从HIV-1蛋白酶解离的途径特异性解离自由能分布图	Vig, E.	PDF	N/A	Pathway Specific Unbinding Free Energy Profiles of Ritonavir Dissociation From HIV-1 Protease
N-甲酰犬尿氨酸，而非犬尿氨酸，进入免疫调节犬尿氨酸途径中的亲核试剂清除分支。	Wang, Y.	PDF	N/A	N-formylkynurenine but not kynurenine enters a nucleophile-scavenging branch of the immune-regulatory kynurenine pathway
通过隐秘的青霉素结合蛋白型硫酯酶实现的生物催化四肽大环化	Jeannette, P. L.	PDF	N/A	Biocatalytic Tetrapeptide Macrocyclization by Cryptic Penicillin-binding Protein-type Thioesterases
基于CRISPR的谱系追踪数据快速准确重建细胞谱系树的动态规划算法	Dai, J.	PDF	N/A	Dynamic programming algorithms for fast and accurate cell lineage tree reconstruction from CRISPR-based lineage tracing data
核小体凝聚物和连接DNA改变了染色质折叠的路径和速率	Qiu, Y.	PDF	N/A	Nucleosome condensate and linker DNA alter chromatin folding pathways and rates
多样化的群体感应系统调控着深海冷泉中微生物的交流和生物地球化学过程。	Peng, J.	PDF	N/A	Diverse quorum sensing systems regulate microbial communication and biogeochemical processes in deep-sea cold seeps
# BioRxiv 2024-11-15 Papers

标题	作者	PDF链接	代码仓库	Title
MIRAGE：一种结合变异功能信息的贝叶斯稀有变异关联分析方法	Han, S.	PDF	N/A	MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants
UFMTrack：下流迁移追踪器，能够在微流控设备中对跨越血脑屏障的整个多步骤免疫细胞渗出级联进行分析	Vladymyrov, M.	PDF	N/A	UFMTrack: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices
基因组大小进化与毒蛙科（Dendrobatidae）的表型关联	Douglas, T. E.	PDF	N/A	Genome size evolution and phenotypic correlates in the poison frog family Dendrobatidae
古代和现代伊比利亚牛中野牛杂交的基因组遗产	Günther, T.	PDF	N/A	The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle
人类额叶皮层的刺激表征支持工作记忆中的灵活控制	Shao, Z.	PDF	N/A	Stimulus representation in human frontal cortex supports flexible control in working memory
鞘脂调控的突触核蛋白-1包涵体的成熟与解毒作用	Cao, X.	PDF	N/A	Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids
复杂性状的普遍多基因性会夸大转录组全关联研究中的假阳性率	Liang, Y.	PDF	N/A	Pervasive polygenicity of complex traits inflates false positive rates in transcriptome-wide association studies
行为药理学预测阿尔茨海默病风险基因斑马鱼突变体中的信号通路紊乱及候选治疗药物	Kroll, F.	PDF	N/A	Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebrafish mutants of Alzheimer's disease risk genes
焦点粘附内整合素纳米簇的空间差异调控与激活	Keary, S.	PDF	N/A	Differential spatial regulation and activation of integrin nanoclusters inside focal adhesions
TIPPo：一种用户友好的工具，用于利用HiFi数据从头组装细胞器基因组	Xian, W.	PDF	N/A	TIPPo: A User-Friendly Tool for De Novo Assembly of Organellar Genomes with HiFi Data
环境和种内及种间相互作用都会影响海洋捕食者的移动。	Mourier, J.	PDF	N/A	Both environmental conditions and intra- and interspecific interactions influence the movements of a marine predator
所有细菌基因组 - 已组装、可用且可搜索的所有细菌基因组	Hunt, M.	PDF	N/A	AllTheBacteria - all bacterial genomes assembled, available and searchable
一刀切不可取：确定远程相机陷阱实际视野范围的新方法	Carswell, B. M.	PDF	N/A	One size does not fit all: a novel approach for determining the Realised Viewshed Size for remote camera traps
协调印度各地的树木库存数据集可以填补热带生态学中的关键空白。	Anujan, K.	PDF	N/A	Harmonising distributed tree inventory datasets across India can fill critical gaps in tropical ecology
基于深度学习的细胞骨架分割技术，用于精确高效地测量细胞骨架密度	Horiuchi, R.	PDF	N/A	Deep learning-based cytoskeleton segmentation for accurate high-throughput measurement of cytoskeleton density
使用Zarr进行生物银行规模分析就绪的VCF	Czech, E. A.	PDF	N/A	Analysis-ready VCF at Biobank scale using Zarr
紧密匹配的比较表明，可分离的过程介导了上下文大小错觉。	Schwarzkopf, D. S.	PDF	N/A	Closely matched comparisons suggest that separable processes mediate contextual size illusions
一个低活动性的皮层网络专门编码句法	Morgan, A. M.	PDF	N/A	A low-activity cortical network selectively encodes syntax
视觉隐性学习中的结构转移与巩固	Garber, D.	PDF	N/A	Structure transfer and consolidation in visual implicit learning
结合AI与MD模拟，发现猴痘病毒H3中的硫酸乙酰肝素结合域作为抗痘病毒药物靶点	Zheng, B.	PDF	N/A	Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combing AI and MD Simulations
新热带生物多样性指标的基因组学：两种蝴蝶辐射，伴随着广泛的染色体重排和杂交	van der Heijden, E. S.	PDF	N/A	Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation
共享环境使得利用菌株解析的宏基因组学来推断微生物群落传播变得复杂。	Debray, R.	PDF	N/A	Shared environments complicate the use of strain-resolved metagenomics to infer microbiome transmission
HSPA2在卵裂球中的不对称表达决定了胚胎的第一次细胞命运决定。	Gao, J.	PDF	N/A	The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision
小脑浦肯野细胞直接输出到脑干的特征	Chen, C. H.	PDF	N/A	Characterization of direct Purkinje cell outputs to the brainstem
数据引导的人类成纤维细胞直接重编程为造血谱系	Stansbury, C.	PDF	N/A	Data-guided direct reprogramming of human fibroblasts into the hematopoietic lineage
是的，它们都是独立的个体：用于重复调查数据的层次模型能够改进对树木生长和尺寸的估计。	O'Brien, T.	PDF	N/A	Yes, they're all individuals: Hierarchical models for repeat survey data improve estimates of tree growth and size
细胞-细胞外基质（ECM）粘附的局部减弱通过细胞形态、肌动蛋白-肌球蛋白组织和E-钙粘蛋白水平的变化，触发了基底组织的折叠。	Valencia-Exposito, A.	PDF	N/A	Local weakening of cell-ECM adhesion triggers basal tissue folding via changes in cell shape, actomyosin organization and E-cad levels
饮食诱导的肥胖中，时间限制性进食对小胶质细胞代谢的改善有限	Jiao, H.	PDF	N/A	Limited microglial metabolic improvement with time-restricted feeding in diet-induced obesity
抑制去泛素化酶活性和炎症信号传导的分子胶	Chandler, F.	PDF	N/A	Molecular glues that inhibit deubiquitylase activity and inflammatory signalling
质子化/去质子化驱动的低电位铁氧还蛋白氧化还原稳定性开关	Wada, K.	PDF	N/A	Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin
单细胞微藻生命周期中r策略与K策略的转变	Liu, L.	PDF	N/A	A shift between r and K strategies in the life cycle of a unicellular microalga
相机陷阱无法确定橡皮泥制作的毛毛虫模型是否能可靠地测量鸟类捕食情况。	SCHILLE, L.	PDF	N/A	Camera traps unable to determine whether plasticine models of caterpillars reliably measure bird predation
脂滴靶向ABHD5和PNPLA3 I148M是促进肝脏脂肪变性所必需的	Teskey, G.	PDF	N/A	Lipid Droplet Targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis
光化学分析突触和突触外NMDA受体分子多样性	Sicard, A.	PDF	N/A	Optochemical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites
贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。	Georgiadou, A.	PDF	N/A	Anemia and tissue hypoxia are major determinants of malarial hypelactatemia
撤回：MIRAGE：一种结合变异功能信息的贝叶斯稀有变异关联分析方法	Han, S.	PDF	N/A	WITHDRAWN: MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants
NACHO介导的五聚配体门控离子通道组装机制	Hooda, Y.	PDF	N/A	Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels
从单个词汇到句子生成：共享的皮层表征，但时间动态不同	Morgan, A. M.	PDF	N/A	From single words to sentence production: Shared cortical representations but distinct temporal dynamics
光流解析作为因果源分离：一种从光流中并行提取物体和自运动信息的计算模型	Scherff, M.	PDF	N/A	Flow parsing as causal source separation: A computational model for concurrent retrieval of object and self-motion information from optic flow
多维社会关系塑造了猴子的社会关注	Liu, S.	PDF	N/A	Multi-dimensional social relationships shape social attention in monkeys
QT-WEAVER：纠正四重分布尽管基因树估计错误，仍能提高系统基因组学分析	Hasan, N. B.	PDF	N/A	QT-WEAVER: Correcting quartet distribution improves phylogenomic analyses despite gene tree estimation error
杨树：一种系统发育分析流程	Koning, E.	PDF	N/A	Poplar: A Phylogenetics Pipeline
影响贝宁北部被忽视和未充分利用物种消费趋势的食品环境因素	BANKOLE, B. M. V.	PDF	N/A	Food environment components influencing consumption trends of neglected and underutilized species in northern Benin
长春新碱治疗逆转局灶节段性肾小球硬化中的足细胞损伤	Mason, W. J.	PDF	N/A	Vincristine treatment reverses podocyte damage in focal segmental glomerulosclerosis
确认气候变化对生物多样性的影响：全球调查结果	Alshehab, E. A.	PDF	N/A	Confirming the Impact of Climate Change on Biodiversity: Results from a Global Survey
AGAPE（计算G四链体亲和力预测）：首个用于G四链体结合亲和力预测的AI体内工作流程。	D'Anna, L.	PDF	N/A	AGAPE (computAtional G-quadruplex Affinitiy PrEdiction): The first AI In-silico workflow for G-quadruplex binding affinity prediction.
CPSM：用于预测单个癌症患者生存概率的自动化机器学习管道的R包	Kaur, H. T.	PDF	N/A	CPSM: R-package of an Automated Machine Learning Pipeline for Predicting the Survival Probability of Single Cancer Patient
分层糖酵解途径调控人类肠道拟杆菌中碳水化合物利用调节因子	Kabonick, S. G.	PDF	N/A	Hierarchical glycolytic pathways control the carbohydrate utilization regulator in human gut Bacteroides
ABA通过提高苹果根系中的脂肪酸水平，促进丛枝菌根真菌的定殖。	Jing, S.	PDF	N/A	ABA increases fatty acids levels in apple roots to boost colonization by arbuscular mycorrhizal fungi
非模式纤毛虫奇洛顿内拉·翁西纳塔（Chilodonella uncinata）的基因组内容：对其核结构、发育过程中体细胞大核内总DNA中基因大小染色体的见解	Ahsan, R.	PDF	N/A	Genome content in the non-model ciliate Chilodonella uncinata: insights into nuclear architecture, gene-sized chromosomes among the total DNA in their somatic macronuclei during their development
在典型的“活化石”谱系中，表型进化的变异模式	Rivero-Vega, R. A.	PDF	N/A	Variable patterns of phenotypic evolution among canonical 'living fossil' lineages
靶向降解易凝结的内源蛋白质可提高作物性能	Xu, G.	PDF	N/A	Targeted degradation of endogenous condensation-prone proteins improves crop performance
叶面积大小决定了玉米在受损和植食性昆虫诱导下挥发性物质的释放量。	Waterman, J. M.	PDF	N/A	Leaf size determines damage- and herbivore-induced volatile emissions in maize
大海捞针：从植物根部培养对植物有益的柔膜菌目菌株	Bruyant, P.	PDF	N/A	Needle in a haystack: culturing plant-beneficial Helotiales lineages from plant roots
野猪源微生物移植对仔猪微生物群、代谢物谱及肠道促炎细胞因子产生的影响与母猪源微生物移植不同。	Willing, B. P.	PDF	N/A	The impact of wild-boar derived microbiota transplantation on piglet microbiota, metabolite profile and gut proinflammatory cytokine production differs from sow-derived microbiota
从初始多能性到人类神经类器官：通过三维形态发生连续体	Laterza, C.	PDF	N/A	From naïve pluripotency to human neural organoids through a three-dimensional morphogenetic continuum
特瓦坎谷的种子传播效果及植物-鸟类相互作用网络	Contreras-Gonzalez, A. M.	PDF	N/A	Seed dispersal effectiveness and plant-bird interaction networks in the Tehuacan Valley
地中海植物物种与食草性节肢动物的关联及其对有机葡萄园中害虫数量的影响	Santos, R.	PDF	N/A	The association of Mediterranean plant species with herbivorous arthropods and its effect on pest abundance in organic vineyards
通过结构建模和分化时间估算，理解植物和真菌病毒中RNA聚合酶的进化和功能关系	Gracy, J.	PDF	N/A	Understanding evolutionary and functional relationships of RNA polymerases in plant and fungal viruses through structural modeling and divergence date estimations
斑胸草雀对鸣叫类型的分类和语义感知	Elie, J. E.	PDF	N/A	Categorical and semantic perception of the meaning of call-types in zebra finches
玩还是不玩？玩伴熟悉度和社会隔离对三种实验室大鼠社交玩耍参与度的影响	Orsucci, I. C.	PDF	N/A	To Play or Not to Play? Effects of Playmate Familiarity and Social Isolation on Social Play Engagement in Three Laboratory Rat Strains
光捕获复合物II通过脂质再分配抵抗植物类囊体膜中非双层脂质诱导的多态性	Garg, A.	PDF	N/A	Light Harvesting Complex II Resists Non-Bilayer Lipid-Induced Polymorphism in Plant Thylakoid Membranes via Lipid Redistribution
双子叶植物茎对低红光：远红光的响应中的皮层细胞反应	Li, L.	PDF	N/A	Pith cell responses to low red: far-red light in dicot stems
植物原生质体的动态皮层行为揭示了植物和动物细胞之间意想不到的相似性	Dickmann, J. E. M.	PDF	N/A	Dynamic cortical behavior of plant protoplasts reveals unexpected similarities between plant and animal cells
拟南芥I类成形蛋白AtFH5有助于幼苗抵抗盐胁迫。	Kollarova, E.	PDF	N/A	The Arabidopsis Class I formin AtFH5 contributes to seedling resistance to salt stress.
高可塑性增加了表型与环境的错配，导致未充分利用的作物物种表现不佳。	Alagarasan, G.	PDF	N/A	High plasticity increases phenotype-environment mismatch leading to sub-optimal performance in underutilized crop species
寡聚半乳糖醛酸，由甜菜副产品的酶促降解产生，对小麦白粉病具有部分保护作用。	Carton, C.	PDF	N/A	Oligogalacturonides, produced by enzymatic degradation of sugar beet by-products, confer partial protection against wheat powdery mildew
大豆胞囊线虫抗性蛋白AATRhg1影响氨基酸稳态和甜菜色素积累	Du, Y.	PDF	N/A	Soybean Cyst Nematode-Resistant Protein AATRhg1 Affects Amino Acid Homeostasis and Betalain Accumulation
内生蚯蚓提取物对“促植物生长真菌”的影响	Yakkou, L.	PDF	N/A	Effect of endogenous earthworm's extracts on "plant growth-promoting fungi"
晚分生组织身份2调控种子表面的角质层形成，并影响种子的寿命。	Oshima, Y.	PDF	N/A	LATE MERISTEM IDENTITY2 regulates cuticle formation on the seed surface and influences seed longevity
光系统II组装因子RBD1和HCF136的拮抗作用是植物叶绿体中光调控psbA翻译的基础	Rojas, M.	PDF	N/A	Opposing action of photosystem II assembly factors RBD1 and HCF136 underlies light-regulated psbA translation in plant chloroplasts
半冬性甘蓝型油菜品种中双11中FLOWERING LOCUS T相关基因的特征及其潜在的基因调控网络	Wang, J. K.	PDF	N/A	Characterization of FLOWERING LOCUS T related genes and their putative gene regulatory network in semi-winter Brassica napus cultivar Zhongshaung11
在黑暗条件下，早期幼苗的发育直接受到质体通过GUN1依赖性质体逆行途径的调控。	Sajib, S. A.	PDF	N/A	Early seedling development in dark conditions is directly controlled by plastids through the GUN1-dependent plastid retrograde pathway
通过机器学习解密植物复杂的表现型特征	Zdrazil, J.	PDF	N/A	Decrypting the complex phenotyping traits of plants by machine learning
乳酸片球菌在酸性胁迫下形态变化的计算分析	Venugopal, A.	PDF	N/A	Computational analysis of morphological changes in Lactiplantibacillus plantarum under acidic stress
UCE系统发育基因组学揭示了收获蚁属（Pogonomyrmex）的系统分类学和地理分布范围的演化	Graber, L. C.	PDF	N/A	UCE phylogenomics inform the systematics and geographic range evolution of the harvester ant genus Pogonomyrmex
复合序列基序的信息论：复杂分子识别的突变和生物物理决定因素	Mascolo, E.	PDF	N/A	Information Theory of Composite Sequence Motifs: Mutational and Biophysical Determinants of Complex Molecular Recognition
植物类囊体膜边缘区域的脂质多态性	Böde, K.	PDF	N/A	Lipid polymorphism of the marginal region of plant thylakoid membranes
SSNA1自组装及其微管结合在中心粒维持中的结构洞察	Agostini, L.	PDF	N/A	Structural insights into SSNA1 self-assembly and its microtubule binding for centriole maintenance
脂质翻转酶ATP9A和ATP9B形成复合体，并参与从高尔基体到分泌途径的贡献。	Yagi, T.	PDF	N/A	Lipid flippases ATP9A and ATP9B form a complex and contribute to the secretory pathway from the Golgi apparatus
Smc5/6与微管的结合调控着动态的着丝粒周围染色质折叠	Carre-Simon, A.	PDF	N/A	Smc5/6 association with microtubules controls dynamic pericentromeric chromatin folding
上游开放阅读框在果蝇进化和发育过程中缓冲翻译变异性	Sun, Y.	PDF	N/A	Upstream open reading frames buffer translational variability during Drosophila evolution and development
昆虫在CENP-T蛋白家族中进化出了单体组蛋白折叠结构域	Sankaranarayanan, S. R.	PDF	N/A	Insects evolved a monomeric histone-fold domain in the CENP-T protein family
一种新型秀丽隐杆线虫Tau扩散模型揭示了内溶酶体完整性和种子Tau聚集的关键基因	Sandhof, C. A.	PDF	N/A	A Novel C. elegans Model for Tau spreading Reveals Genes Critical for Endolysosomal Integrity and Seeded Tau Aggregation
Pin4 链接：酵母中葡萄糖饥饿后的转录后和转录反应	Ristova, M.	PDF	N/A	Pin4 Links Post-transcriptional and Transcriptional Responses to Glucose Starvation in Yeast
跨物种类器官揭示了多巴胺能神经元发育和脆弱性的人类特异性分子特征	Nolbrant, S.	PDF	N/A	Interspecies Organoids Reveal Human-Specific Molecular Features of Dopaminergic Neuron Development and Vulnerability
妊娠期长度驱动有胎盘哺乳动物的大脑尺寸和胎仔数量变化	Danis, T.	PDF	N/A	Gestation length drives brain size and litter size variation in eutherian mammals
AI辅助成像筛查揭示了机械分子组织者和信号枢纽网络。	Bertocchi, C.	PDF	N/A	AI-assisted imaging screening reveals mechano-molecular tissue organizers and network of signaling hubs.
TopLib：构建和搜索自上而下的质谱库，用于蛋白质变体鉴定	Li, K.	PDF	N/A	TopLib: Building and searching top-down mass spectral libraries for proteoform identification
iModMix：多组学数据的综合模块分析	Narvaez-Bandera, I. Y.	PDF	N/A	iModMix: Integrative Module Analysis for Multi-omics Data
VIRALpre：融合K-mer特征的病毒基因组基础模型嵌入用于病毒识别	Wang, Z.	PDF	N/A	VIRALpre: Genomic Foundation Model Embedding Fused withK-mer Feature for Virus Identification
AlphaRING：通过蛋白质建模和残基相互作用网络分析进行错义变异分类	Logsdon, A.	PDF	N/A	AlphaRING: Missense Variant Classification via Protein Modelling and Residue Interaction Network Analysis
利用基因表达数据预测多发性骨髓瘤分期和MGUS进展的机器学习模型	Karathanasis, N.	PDF	N/A	Machine Learning Models for Predicting Multiple Myeloma Staging and MGUS Progression Using Gene Expression Data
肌球蛋白II细丝结构特性对力生成的影响	Ding, S.	PDF	N/A	Impacts of Structural Properties of Myosin II Filaments on Force Generation
在乳腺癌中，维持CDK4/6抑制剂并结合CDK2抑制剂超越进展的治疗益处	Armand, J.	PDF	N/A	Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer
昼夜节律基因Dec2通过调控肿瘤细胞抗原呈递促进免疫逃逸，从而促进胰腺癌休眠。	Harris, C. R.	PDF	N/A	The circadian gene Dec2 promotes pancreatic cancer dormancy by regulating tumor cell antigen presentation to facilitate immune evasion
啮齿动物的垂直袖状胃切除术：对母亲代谢、心血管和肝脏功能的影响及围产期后果	Payen, C.	PDF	N/A	Vertical sleeve gastrectomy in rodents: impact on metabolic, cardiovascular and hepatic functions of mothers and perinatal consequences
需要能力建设以充分利用获取生物多样性收藏的益处	Groom, Q.	PDF	N/A	Capacity building needed to reap the benefits of access to biodiversity collections
T细胞介导的克罗恩病上皮完整性损害	Hamoudi, S.	PDF	N/A	T cell mediated impairment of epithelial integrity in Crohn's disease
慢性炎症驱动附睾三级淋巴结构形成和自身免疫性生育障碍	Elizagaray, M. L.	PDF	N/A	Chronic inflammation drives epididymal tertiary lymphoid structure formation and autoimmune fertility disorders
ENTPD3特异性CAR调节性T细胞用于T1D的局部免疫控制	Pieper, T.	PDF	N/A	ENTPD3-specific CAR Regulatory T cells for Local Immune Control in T1D
AIP56是由杀鱼气单胞菌（Photobacterium damselae subsp. piscicida）分泌的一种AB毒素，它对髓系细胞具有趋向性。	Freitas, I. L.	PDF	N/A	AIP56, an AB toxin secreted by Photobacterium damselae subsp. piscicida, has tropism for myeloid cells
LTB4通过一种受体转激活机制被转化为一种强效的人类中性粒细胞NADPH氧化酶激活剂，其中BLT1受体激活游离脂肪酸受体2。	Wu, Y.	PDF	N/A	LTB4 is converted into a potent human neutrophil NADPH oxidase activator via a receptor transactivation mechanism in which the BLT1 receptor activates the free fatty acid receptor 2
计算机生物群落区划方法	Sukhanov, V.	PDF	N/A	Computer method of biocenotic zoning
火灾后的幼苗更新：解开微生境条件和种子可获得性的作用	Beck, J. J.	PDF	N/A	Seedling recruitment after fire: Disentangling the roles of microsite conditions and seed availability
填补基因组空白：草类作物进化中的泛草类同源基因集	Dias, H. M.	PDF	N/A	Bridging Genomic Gaps: The Pan-Grass Syntenic Gene Set in Grass Crop Evolution
DreaM：一种用于增强重复基因组区域短读序列分析的计算流程	Kumar, S.	PDF	N/A	DreaM: A Computational Pipeline for Enhanced Short-Read Sequence Analysis in Repetitive Genomic Regions
揭示与乳腺癌发展相关的表观遗传调控元件	Jardanowska-Kotuniak, M.	PDF	N/A	Unveiling epigenetic regulatory elements associated with breast cancer development
通过大量和单细胞RNA测序揭示的诺林在神经视网膜分化中的潜在作用	Maggi, K.	PDF	N/A	Putative Role of Norrin in Neuroretinal Differentiation Revealed by bulk and scRNA Sequencing of Human Retinal Organoids
在纳米尺度上，左旋多巴与脑部疾病蛋白质的相互作用	Bergaglio, T.	PDF	N/A	On Levodopa interactions with brain disease proteins at the nanoscale
人类肠神经胶质在急性脑损伤临床前模型中的再生潜力	Colitti, N.	PDF	N/A	Regenerative potential of human enteric glia in a preclinical model of acute brain injury
盲点填补是多感官的	Chan, A.	PDF	N/A	Filling-in of the Blindspot is Multisensory
人脑中的区域脑熵、脑网络及结构-功能耦合	Song, D.	PDF	N/A	Regional Brain Entropy, Brain Network and Structural-Functional Coupling in Human Brain
用于与神经退行性疾病研究界共享的额颞叶痴呆单MAPT敲入小鼠模型	Morito, T.	PDF	N/A	Single MAPT knock-in mouse models of frontotemporal dementia for sharing with the neurodegenerative research community
急性低氧性缺氧对大脑血流反应性的变异性	Johnson, H. R.	PDF	N/A	Variable Cerebral Blood Flow Responsiveness to Acute Hypoxic Hypoxia
睡眠剥夺后的注意力失误代表了脑脊液流动的瞬间。	Yang, Z.	PDF	N/A	Attentional failures after sleep deprivation represent moments of cerebrospinal fluid flow
单细胞分析显示，单核细胞基因表达谱影响急性治疗队列中HIV-1储库的大小	Ehrenberg, P. K.	PDF	N/A	Single-cell analyses reveal that monocyte gene expression profiles influence HIV-1 reservoir size in acutely treated cohorts
一种与侧位、心脏和肾脏缺陷相关的人类WNT11功能丧失型纯合变异	Berns, H. E.	PDF	N/A	A homozygous human WNT11 loss-of-function variant associated with laterality, heart and renal defects
骨形态发生蛋白信号通路与乙醇相互作用破坏了腭的形成，与gata3无关	Lovely, C. B.	PDF	N/A	Bone Morphogenetic Protein signaling pathway - ethanol interactions disrupt palate formation independent of gata3
城市绿地连通性促使宿主群落变化及蜱传病原体感染转变	VanAcker, M. C.	PDF	N/A	Urban greenspace connectivity drive shifts in host assemblages and tick-borne pathogen infection
将机器学习与流式成像显微技术相结合，实现藻华的自动化监测	Khan, F.	PDF	N/A	Integrating Machine Learning with Flow-Imaging Microscopy for Automated Monitoring of Algal Blooms
长读测序揭示了在无脊椎动物-脊椎动物过渡阶段，细胞间信号传导的关键转录因子效应物中同工型多样性的增加	Torres-Aguila, N. P.	PDF	N/A	Long-Read Sequencing Reveals Increased Isoform Diversity in Key Transcription Factor Effectors of Intercellular Signalling at the Invertebrate-Vertebrate Transition
增强GPT模型在基因组学分析中的应用：通过RAG和微调生成可信的遗传变异注释与解读	Lu, S.	PDF	N/A	Boosting GPT Models for Genomics Analysis: Generating Trusted Genetic Variant Annotations and Interpretations through RAG and fine-tuning
组织微环境中的破坏性变化在肺癌发生不同阶段促进了致癌过程的启动。	Venkat, V.	PDF	N/A	Disruptive changes in tissue microenvironment prime oncogenic processes at different stages of carcinogenesis in lung
体积和扩散张量成像生物标志物表明，在轻度创伤性脑损伤的青年猪模型中，存在长期持续的脑震荡后异常。	Islam, S.	PDF	N/A	Volumetric and Diffusion Tensor Imaging biomarkers indicating long lasting post-concussion abnormalities in a youth pig model of mild Traumatic Brain Injury
多级混合制备核壳结构显著提升载DNA脂质纳米粒的转染效率，提升幅度达数量级。	Nong, J.	PDF	N/A	Multi-stage-mixing to create a core-then-shell structure improves DNA-loaded lipid nanoparticles transfection by orders of magnitude
通过多重电化学实时局部炎症追踪一氧化氮传感器（MERLIN）进行伤口状态监测	Wang, L.	PDF	N/A	Wound state monitoring by multiplexed, electrochemical, real-time, localized, inflammation-tracking nitric oxide sensor (MERLIN)
HSPB5中的蛋白稳态相关变异破坏了αB-晶体蛋白结构域的稳定性	Khatun, M. S.	PDF	N/A	Proteostasis Associated Variants in HSPB5 Destabilize the αB-crystallin Domain
使用MMseqs2进行GPU加速的同源搜索	Kallenborn, F.	PDF	N/A	GPU-accelerated homology search with MMseqs2
使用参数高效的迁移学习进行免疫蛋白的精确结构预测	Zhu, T.	PDF	N/A	Accurate structure prediction of immune proteins using parameter-efficient transfer learning
用于芽殖酵母无标记基因编辑的自动化质粒设计	Stojkovic, L.	PDF	N/A	Automated plasmid design for marker-free genome editing in budding yeast
scMoE：通过稀疏专家混合实现单细胞多模态多任务学习	Yun, S.	PDF	N/A	scMoE: single-cell Multi-Modal Multi-Task Learning via Sparse Mixture-of-Experts
人类5' UTR序列的多目标计算优化	Yamada, K.	PDF	N/A	Multi-objective computational optimization of human 5' UTR sequences
scTrace+：通过整合谱系追踪和多方面的转录组相似性信息来增强细胞命运推断	Guo, W.	PDF	N/A	scTrace+: enhance the cell fate inference by integrating the lineage-tracing and multi-faceted transcriptomic similarity information
中期染色单体表面凝聚的核内分区	Murugesan, V.	PDF	N/A	Nuclear partitioning by surface condensation on metaphase chromatids
评估NF1突变肿瘤细胞中治疗性自噬抑制的效果	Zahedi, S.	PDF	N/A	The assessment of therapeutic autophagy inhibition in NF1 mutated tumor cells
针对SLC7A11介导的半胱氨酸代谢治疗曲妥珠单抗耐药的HER2阳性乳腺癌	Hua, Y.	PDF	N/A	Targeting SLC7A11-mediated cysteine metabolism for the treatment of trastuzumab resistant HER2 positive breast cancer
精子甲基组对衰老和应激反应的分子基础	Arowolo, O.	PDF	N/A	Molecular Basis of Sperm Methylome Response to Aging and Stress
视觉系统中正向和反向α波段传播波的分层多尺度模型	Schwenk, J. C. B.	PDF	N/A	A hierarchical multiscale model of forward and backward alpha-band traveling waves in the visual system
高分辨率成像图谱揭示了胰腺交感神经支配在糖尿病小鼠中的情境依赖性作用	Xu, Q.	PDF	N/A	High-resolution imaging atlas reveals context-dependent role of pancreatic sympathetic innervation in diabetic mice
国际多队列分析揭示了量化重症疾病中免疫失调的新框架：SUBSPACE联盟研究结果	Moore, A. R.	PDF	N/A	International multi-cohort analysis identifies novel framework for quantifying immune dysregulation in critical illness: results of the SUBSPACE consortium
肺泡巨噬细胞在纳米颗粒吸入过程中启动空间定向的中性粒细胞招募	Liu, Q.	PDF	N/A	Alveolar macrophages initiate the spatially targeted neutrophil recruitment during nanoparticle inhalation
年老的秀丽隐杆线虫（Caenorhabditis elegans）的抗病毒防御能力下降，这是由于DRH-1/RIG-I的去SUMO化作用通过ULP-4/SENP7的丧失所导致的。	Zhang, Y.	PDF	N/A	Antiviral defense in aged Caenorhabditis elegans declines due to loss of DRH-1/RIG-I deSUMOylation via ULP-4/SENP7
通过近红外光谱和云端神经网络实现生物制剂的快速原位检测	Leseigneur, C.	PDF	N/A	Rapid and In-situ Detection of Biological Agents via Near-Infrared Spectroscopy and Cloud-Powered Neural Networks
一项针对肝脏染色体结构的全基因组图谱研究表明，性别决定了饮食诱导的核小体动力学。	ZHANG, Z.	PDF	N/A	A genome-wide ATLAS of liver chromatin architecture reveals that sex dictates diet-induced nucleosome dynamics
自发性高血压易卒中大鼠尿液蛋白质组特征分析	Meng, W.	PDF	N/A	Urinary Proteome Characterization of Stroke-Prone Spontaneously Hypertensive Rats
土耳其商业一品红中相关桃树植原体候选菌株的出现	Benlioglu, K.	PDF	N/A	Occurrence of a Candidatus Phytoplasma pruni Related Strain Associated with Commercial Poinsettias in Turkey
元基因组学洞察：氨回收生物反应器中参与N2O缓解和反硝化还原为氨的活性细菌	Phan, H. V.	PDF	N/A	Meta-omic insights into active bacteria mediating N2O mitigation and dissimilatory nitrate reduction to ammonium in an ammonia recovery bioreactor
顺应潮流：利用礁石尺度的水动力学进行基于幼虫的恢复的规模扩大	Gouezo, M.	PDF	N/A	Going with the flow: leveraging reef-scale hydrodynamics for upscaling larval-based restoration
蚊翅图像库：推进基于几何形态计量学和人工智能识别的研究	Nolte, K.	PDF	N/A	Mosquito Wing Image Repository for Advancing Research on Geometric Morphometric- and AI-Based Identification
更新世海平面波动塑造了濒危的洛德豪岛蟑螂（Panesthia lata）在整个群岛范围内的种群结构。	Adams, M. W. D.	PDF	N/A	Pleistocene sea-level fluctuation shapes archipelago-wide population structure in the Endangered Lord Howe Island cockroach Panesthia lata
首次为三种海葵（珊瑚纲：海葵目）宿主的克隆鱼物种生成了从头HiFi基因组组装	De Jode, A.	PDF	N/A	The first de novo HiFi genome assemblies for three clownfish-hosting sea anemone species (Anthozoa: Actiniaria)
具有自体组织驻留巨噬细胞的人类心脏类器官再现了生理性的免疫-心脏相互作用	O'Hern, C.	PDF	N/A	Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions
在临床质子治疗系统的同步回旋加速器室内，对A549肺癌细胞和IMR90健康人成纤维细胞进行体外FLASH辐照。	Zazpe, A.	PDF	N/A	In vitro FLASH irradiation of A549 lung cancer cells and IMR90 healthy human fibroblasts in the synchrocyclotron room of a clinical proton therapy system
用于狨猴神经科学设备的开放获取资源	Rollin, I. Z.	PDF	N/A	An Open Access Resource for Marmoset Neuroscientific Apparatus
使用CryFold改进冷冻电镜图的自动化模型构建	Su, B.	PDF	N/A	Improved automated model building for cryo-EM maps using CryFold
scCompass：一个集成的跨物种单细胞RNA测序数据库，为AI准备就绪	Wang, P.	PDF	N/A	scCompass: An integrated cross-species scRNA-seq database for AI-ready
无膜细胞器的蛋白质稳态网络的组织	Lim, C. M.	PDF	N/A	Organization of the Proteostasis Network of Membraneless Organelles
超快弹性毛细管风扇控制波纹虫和机器人的敏捷机动	Ortega-Jimenez, V.	PDF	N/A	Ultrafast elastocapillary fans control agile maneuvering in ripple bugs and robots
动态捕获的凝聚融合创造出具有不同材料特性的复杂结构	Erkamp, N. A.	PDF	N/A	Dynamically arrested condensate fusion creates complex structures with varying material properties
由雄激素受体转录激活域与小分子药物形成共价加合物后仍保持无序状态。	Zhu, J.	PDF	N/A	Covalent adducts formed by the androgen receptor transactivation domain and small molecule drugs remain disordered
癌症相关突变对聚腺苷二磷酸核糖聚合酶1抑制作用的影响	Shanmugam, N.	PDF	N/A	Impact of a Cancer-Associated Mutation on Poly(ADP-ribose) Polymerase1 Inhibition
MR-ARFI在人体经颅聚焦超声中的优化	Mohammadjavadi, M.	PDF	N/A	Optimization of MR-ARFI for Human Transcranial Focused Ultrasound
起源的基底细胞解决了癌症中神经内分泌-丛状谱系可塑性	Ireland, A. S.	PDF	N/A	Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer
基于逻辑的机器学习预测艾司西酞普兰如何抑制心肌细胞肥大	Eggertsen, T. G.	PDF	N/A	Logic-based machine learning predicts how escitalopram inhibits cardiomyocyte hypertrophy
无偏倚地发现能够刺激巨噬细胞介导的B细胞淋巴瘤破坏的抗体疗法	Ribeiro, J.	PDF	N/A	Unbiased discovery of antibody therapies that stimulate macrophage-mediated destruction of B-cell lymphoma
酪蛋白2A2通过增强免疫突触内CD45磷酸酶活性促进T细胞免疫调节	Ali, S.	PDF	N/A	Butyrophilin 2A2 promotes T cell immunoregulation by enhancing CD45 phosphatase activity within the immune synapse
RecN和RecA在埃希氏大肠杆菌中协调了环丙沙星暴露后有序的DNA超压缩反应。	Vikedal, K.	PDF	N/A	RecN and RecA orchestrate an ordered DNA supercompaction response following ciprofloxacin exposure in Escherichia coli
一种快速、经济高效的高产DNA从PCR产物和琼脂糖凝胶中纯化的方法。	Fatima, S.	PDF	N/A	A Rapid, Cost-Effective Method for High-Yield DNA Purification from PCR Products and Agarose Gels.
解密金黄色葡萄球菌中含Com_YlbF结构域蛋白质的功能。	Rozo, Z. L. C.	PDF	N/A	Deciphering the function of Com_YlbF domain-containing proteins in Staphylococcus aureus.
Sla2 是网格蛋白轻链与 Pan1/End3/Sla1 复合体之间的核心相互作用枢纽。	Draper-Barr, G.	PDF	N/A	Sla2 is a core interaction hub for Clathrin Light Chain and the Pan1/End3/Sla1Complex
急性呼吸窘迫综合征肺部细胞外基质的组成变化	Fan, Y.	PDF	N/A	Compositional changes of the lung extracellular matrix in acute respiratory distress syndrome
将纳米孔MinION测序整合到国家动物健康抗菌素耐药性监测计划中：一项关于印尼鸡肉屠宰场废水和河流的试点研究	Telussa, R.	PDF	N/A	Integrating Nanopore MinION Sequencing into National Animal Health AMR Surveillance Programs: An Indonesian Pilot Study of Chicken Slaughterhouse Effluent and Rivers
利用绿色和近红外荧光蛋白的荧光交叉相关光谱技术，在活细胞中定量测定细胞周期蛋白-CDK的解离常数。	Toyama, A.	PDF	N/A	Quantification of Cyclin-CDK dissociation constants in living cells using fluorescence cross-correlation spectroscopy with green and near-infrared fluorescent proteins.
揭示珊瑚礁的普遍空间特性	Gimenez-Romero, A.	PDF	N/A	Unravelling the universal spatial properties of coral reefs
在珊瑚Montipora capitata中，遮蔽不会降低其热耐受性：对保护干预的启示	Ducret, H.	PDF	N/A	Shading does not lower thermal tolerance in the coral Montipora capitata: implications for conservation intervention
减去误差：在存在残留对齐错误的情况下估计dN/dS并测试自然选择	Selberg, A.	PDF	N/A	Minus the Error: Estimating dN/dS and Testing for Natural Selection in the Presence of Residual Alignment Errors
蜥蜴和喙头蜥（鳞龙类）中松果体非视觉视蛋白的演化	Romero, R. D.	PDF	N/A	Evolution of pineal non-visual opsins in lizards and the tuatara (Lepidosauria)
重新定义性传播寄生虫阴道毛滴虫及其在鸽形目鸟类中的近缘物种的剪接体内含子	Callejas-Hernandez, F.	PDF	N/A	Redefining the spliceosomal introns of the sexually transmitted parasite Trichomonas vaginalis and its close relatives in columbid birds
使用Takoyaki超声技术对深层组织中的细胞和分子进行实时体积成像	Lee, S.	PDF	N/A	Real-time volumetric imaging of cells and molecules in deep tissues with Takoyaki ultrasound
常见的AAV基因治疗载体表现出对活体人脑细胞类型的无差别转导	McGinnis, J.	PDF	N/A	Common AAV gene therapy vectors show indiscriminate transduction of living human brain cell types
优化VSV G骨架以实现与纳米抗体的氨基端融合，使其能够重新定向至治疗相关受体的受体。	Duquenois, I.	PDF	N/A	Optimization of the VSV G backbone for amino terminal fusion with nanobodies allowing its retargeting to receptors of therapeutic interest.
用于血友病B的通用碱基编辑	Baatartsogt, N.	PDF	N/A	Universal base editing for hemophilia B
高适应度路径可以连接序列重叠度低的蛋白质	Kantroo, P.	PDF	N/A	High fitness paths can connect proteins with low sequence overlap
从知识库、注册表和多组学数据生成生物医学知识图谱	Qin, G.	PDF	N/A	Generating Biomedical Knowledge Graphs from Knowledge Bases, Registries, and Multiomic Data
在优化后的Colab处理器上对GROMACS进行基准测试，以及云计算在分子动力学中的灵活性	Karagöl, T.	PDF	N/A	Benchmarking GROMACS on Optimized Colab Processors and the Flexibility of Cloud Computing for Molecular Dynamics
DDA-BERT：利用基于数据依赖采集质谱的蛋白质组学中的Transformer架构预训练	A, J.	PDF	N/A	DDA-BERT: leveraging transformer architecture pre-training for data-dependent acquisition mass spectrometry-based proteomics
用于预测病毒-人类蛋白质相互作用的机器学习方法：对逆转录病毒相互作用网络的评估	Mahmoudi, O.	PDF	N/A	Machine Learning Approaches for Predicting Virus-Human Protein-Protein Interactions: An Evaluation of Retroviral Interaction Networks
一种用于从头设计抗菌肽的多属性优化生成对抗网络	Liu, J.	PDF	N/A	A Multi-Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design
使用PhenoGeneRanker识别与阿尔茨海默病相关的基因	Rahman, M. T.	PDF	N/A	Identifying Alzheimer's disease-associated genes using PhenoGeneRanker
原子基本通量模式解释了大规模通量网络中代谢物的稳态流动	Chitpin, J. G.	PDF	N/A	Atomic elementary flux modes explain the steady state flow of metabolites in large-scale flux networks
脂质包装缺陷是α-突触核蛋白膜结合的必要且充分条件	Johnson, D. H.	PDF	N/A	Lipid Packing Defects are Necessary and Sufficient for Membrane Binding of alpha-Synuclein
人类线粒体复制解旋酶的实时动力学自动调节	Plaza G-A, I.	PDF	N/A	Auto-regulation of the real-time kinetics of the human mitochondrial replicative helicase
通过不对称纳米孔解析电流整流	Lin, Y.	PDF	N/A	Dissecting current rectification through asymmetric nanopores
利用染色质包装域在体内靶向化疗逃逸	Frederick, J.	PDF	N/A	Leveraging chromatin packing domains to target chemoevasion in vivo
空间排斥抵消了ER到脂滴的蛋白质运动	Damm, A.	PDF	N/A	Steric Repulsion Counteracts ER-to-Lipid Droplet Protein Movement
一个稳健的计算框架，用于优化CDK7抑制剂作为有前景的癌症疗法	Shi, Z.	PDF	N/A	A Robust Computational Framework for the Optimization of CDK7 Inhibitors as Promising Cancer Therapy
糖皮质激素受体凝聚物在转录调控中的标志	Benitez, B.	PDF	N/A	Hallmarks of glucocorticoid receptor condensates involvement in transcription regulation
C1C2通道视紫红质开启机制的结构见解	Mulder, M.	PDF	N/A	Structural insights into the opening mechanism of C1C2 channelrhodopsin
波形蛋白中的单一半胱氨酸残基通过调控长链非编码RNA XIST，抑制乳腺癌中的上皮-间质转化及干细胞特性	Usman, S.	PDF	N/A	A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer
代谢重编程与染料木黄酮和化疗在人乳腺癌细胞中的协同细胞毒性	Tobon-Cornejo, S.	PDF	N/A	Metabolic reprogramming and synergistic cytotoxicity of genistein and chemotherapy in human breast cancer cells
5q缺失型急性髓系白血病是一种表观遗传学上独特的亚群，其特征是KDM3B的杂合性缺失。	Kelly, K.	PDF	N/A	Acute Myeloid Leukemia with deletion 5q is an epigenetically distinct subgroup defined by heterozygous loss of KDM3B
古生态系统的选择、演化和持久性	Roopnarine, P. D.	PDF	N/A	Selection, Evolution and Persistence of Paleoecological Systems
表观遗传调节NLRP6炎症小体传感器作为一种治疗手段，以减少HIV/SIV感染中由坏死性凋亡驱动的胃肠道黏膜功能障碍	Premadasa, L. S.	PDF	N/A	Epigenetic modulation of NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection
激素诱导的血栓形成是通过非经典的纤维蛋白（原）聚集和斑马鱼中一种新的雌激素靶点介导的。	Yu, X.	PDF	N/A	Hormone-induced thrombosis is mediated through non-canonical fibrin(ogen) aggregation and a novel estrogen target in zebrafish
全动物表型药物筛选鉴定出抑制动脉粥样硬化脂蛋白的药物。	Kelpsch, D. J.	PDF	N/A	A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins.
量化环境传播和年龄特异性易感性的关键参数，针对鸟分枝杆菌副结核亚种（MAP）	Gao, Y.	PDF	N/A	Quantifying Key Parameters of Environmental Transmission and Age-Specific Susceptibility for Mycobacterium avium subspecies paratuberculosis (MAP)
饮食限制增强CD8+ T细胞酮体代谢以限制衰竭并提升抗肿瘤免疫	Oswald, B. M.	PDF	N/A	Dietary Restriction Enhances CD8+ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity
新发现的鼠CD103-树突状细胞是高度免疫活性的常规DC2亚群，与已知的鼠和人类树突状细胞亚群相对应。	Sawanobori, Y.	PDF	N/A	Newly found rat CD103- dendritic cells are the highly immunogenic conventional DC2 subpopulation, corresponding to the known DC subsets in mice and humans.
伴随文章：《嗜酸性食管炎中牛奶过敏原免疫识别的分子基础》	Dilollo, J.	PDF	N/A	Companion to: A molecular basis for milk allergen immune recognition in eosinophilic esophagitis
利用核糖体图谱技术揭示新型保守的HIV-1开放阅读框，编码T细胞抗原。	Bertrand, L.	PDF	N/A	Unveiling novel conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling.
揭示流感A病毒中的重配现象：TreeSort的应用	Markin, A.	PDF	N/A	Revealing reassortment in influenza A viruses with TreeSort
多层次的生态相互作用决定了临床耐药菌株在人类微生物群中的生长	Leon-Sampedro, R.	PDF	N/A	Multi-layered ecological interactions determine growth of clinical antibiotic-resistant strains within human microbiomes
温度调节疟蚊共生体微孢子虫MB的传播潜力，该共生体可阻断疟疾传播	Otieno, F. G.	PDF	N/A	Temperature modulates the dissemination potential of Microsporidia MB, a malaria-blocking endosymbiont of Anopheles mosquitoes
利用包膜二聚体开发蜱传脑炎病毒纳米颗粒疫苗	Wang, B.	PDF	N/A	Development of a tick-borne encephalitis virus nanoparticle vaccine utilizing envelope dimer
促炎通路在小鼠模型中参与艰难梭菌感染的发病机制——一项空间转录组学研究	Ghahari, N.	PDF	N/A	Pro-inflammatory Pathways Contribute to Pathogenesis of Clostridioides difficile Infection in a Murine Model - A Spatial Transcriptomics Study
探索人类TSG101的UEV结构域的药物潜力，以寻找广谱抗病毒药物	Montero, F.	PDF	N/A	Exploring the druggability of the UEV domain of human TSG101 in search for broad-spectrum antivirals
KPC-14的特性：一种KPC变异体，赋予广泛耐药的ST463铜绿假单胞菌临床分离株对头孢他啶-阿维巴坦的耐药性	Xiao, Y.	PDF	N/A	Characteristic of KPC-14, a KPC Variant Conferring Resistance to Ceftazidime-Avibactam in the Extensively Drug-resistant ST463 Pseudomonas aeruginosa Clinical Isolate
通过基于原位荧光杂交的光学筛选鉴定ALT途径的新型调节因子	Azeroglu, B.	PDF	N/A	Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical Screen
autoFISH - 一个用于连续单分子荧光原位杂交实验的模块化工具箱	Weber, C.	PDF	N/A	autoFISH - a modular toolbox for sequential smFISH experiments
外泌体中miRNAs分选的负调控：RNA结合蛋白PCBP2损害SYNCRIP介导的miRNAs外泌体装载	Marocco, F.	PDF	N/A	Negative regulation of miRNAs sorting in EVs: the RNA-binding protein PCBP2 impairs SYNCRIP-mediated miRNAs EVs loading
排斥性客户关机在Yb体内的短暂寄居在Piwi-piRISC生物发生和维持生育能力中起着关键作用。	Hirakata, S.	PDF	N/A	Transient residence of the repulsive client Shutdown in Yb bodies plays a critical role in Piwi-piRISC biogenesis and maintaining fertility
ATR保护复制叉免受APOBEC3B诱导的有害PARP1捕获的影响	Ortega, P.	PDF	N/A	ATR safeguards replication forks against APOBEC3B-induced toxic PARP1 trapping
恢复PKM1通过调节PEP代谢改善人干细胞衍生的β细胞的功能成熟	Lin, H.	PDF	N/A	Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism
顶复门DedA超家族蛋白VMP1对于分泌器官的生物发生和功能至关重要	Reddy, G. S.	PDF	N/A	The apicomplexan DedA superfamily protein VMP1 is crucial for the biogenesis and function of secretory organelles
Jagged1是一种在血管内皮细胞中独立于Notch的机械转导因子。	Suarez Rodriguez, F.	PDF	N/A	Jagged1 is a Notch-independent mechanotransducer in endothelial cells
通过体表碳氢化合物识别合适交配伴侣——一种具有极端同性二态性的物种	Moris, V. C.	PDF	N/A	Recognition of an appropriate mating partner using cuticular hydrocarbons in a species with an extreme intra-sexual dimorphism
吸引猎物但不被捕食者排斥表明在遭遇-躲避-逃脱序列中存在不对称的投资。	Ferry, N.	PDF	N/A	Prey attracting but not repelled by predators suggests an asymmetric investment in the encounter-avoid-escape sequence.
从恐惧到盛宴：响尾蛇在恐惧的景观中导航以优化觅食	Da Cunha, O.	PDF	N/A	FROM FEAR TO FEAST: RATTLESNAKES NAVIGATE THE LANDSCAPE OF FEAR TO OPTIMIZE FORAGING
恢复的生物标志物：生态修复后营养流动的特征化	Spindel, N. B.	PDF	N/A	Biomarkers of recovery: characterizing trophic flow following ecological restoration
大象应该吃草还是吃树叶？杂食性巨型草食动物饮食变化的养分和功能后果	Gautam, H.	PDF	N/A	Should elephants graze or browse? The nutritional and functional consequences of dietary variation in a mixed-feeding megaherbivore
来自较高羊膜动物的CGGBP1限制胞嘧啶甲基化，并在被抑制的启动子处驱动转录因子结合位点的GC偏向性	Kumar, P.	PDF	N/A	CGGBP1 from higher amniotes restricts cytosine methylation and drives a GC-bias in transcription factor binding sites at repressed promoters
扩展的“共同原因”：间断进化与沉积过程之间的因果联系	Polly, P. D.	PDF	N/A	The extended 'common cause': causal links between punctuated evolution and sedimentary processes
三刺鱼中的新生突变率	Zhang, C.	PDF	N/A	Rate of de novo mutations in the three-spined stickleback
热带岛屿特有鸟类的种群数量对气候的响应受到栖息地可用性和物种特性的调节。	Karjee, R.	PDF	N/A	Tropical island endemic birds' demographic responses to climate are modulated by habitat availability and species traits
通过连续不对称减数分裂实现的自我抑制性染色体驱动	Meng, X.	PDF	N/A	Self-restrained sex chromosome drive through sequential asymmetric meiosis
结合功能注释和多性状精细定位方法可提高血糖性状位点的精细定位分辨率	Soenksen, J.	PDF	N/A	Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci
在生物实验中使用逻辑回归和Cochran-Mantel-Haenszel检验对分类数据进行分析	Androwski, R. J.	PDF	N/A	Analysis of Categorical Data with Logistic Regression and the Cochran-Mantel-Haenszel Tests in Biological Experiments
苦味基因与口腔健康：加拿大老龄化纵向研究	Shafizadeh, M.	PDF	N/A	Bitter taste genetics and oral health in Canadian Longitudinal Study on Aging
多视角最佳线性无偏预测（Multi-view BLUP）：一种有前景的后组学数据整合预测方法	Wu, B.	PDF	N/A	Multi-view BLUP: a promising solution for post-omics data integrative prediction
端粒重复序列含RNA在老化的人类细胞中增加	Chu, H.-P. C.	PDF	N/A	Telomeric Repeat-Containing RNA Increases in Aged Human Cells
CUT&RUN峰值调用方法的基准测试	Nooranikhojasteh, A.	PDF	N/A	Benchmarking Peak Calling Methods for CUT&RUN
对PeptideAtlas数据库的深入审计揭示了未注释编码基因和异常翻译的证据。	Rodriguez, J. M.	PDF	N/A	A deep audit of the PeptideAtlas database uncovers evidence for unannotated coding genes and aberrant translation
DNA拓扑异构酶Top2的减少能够重新编程表观遗传景观，并在多个物种中延长健康和寿命。	Zhu, M.	PDF	N/A	Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species
来自L. meyenii Walp的脂质纳米颗粒通过多模态蛋白质冠形成减轻脓毒症	Sung, J. J.	PDF	N/A	Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation
预测喉镜图像中的语义分割质量	Kist, A. M.	PDF	N/A	Predicting semantic segmentation quality in laryngeal endoscopy images
体积成像与计算技术在斑马鱼心脏收缩功能研究中的应用	Saberigarakani, A.	PDF	N/A	Volumetric imaging and computation to explore contractile function in zebrafish hearts
非角化颊部组织在负压冲击下的有限元模型	Klein Cerrejon, D.	PDF	N/A	Finite element model of the non-keratinized buccal tissue under the impact of negative pressure
SMAC：利用SMRT CCS数据在单分子水平上鉴定DNA N6-甲基腺苷（6mA）	Li, H.	PDF	N/A	SMAC: identifying DNA N6-methyladenine (6mA) at the single-molecule level using SMRT CCS data
InterPLM：通过稀疏自编码器在蛋白质语言模型中发现可解释的特征	Simon, E.	PDF	N/A	InterPLM: Discovering Interpretable Features in Protein Language Models via Sparse Autoencoders
利用蛋白质语言模型对蛋白质-肽结合亲和力进行排序	Chalas, C. C.	PDF	N/A	Ranking protein-peptide binding affinities with protein language models
解密姜黄素对乳腺癌中组蛋白标记的表观遗传影响：基于3D网络的研究	Tang, T.	PDF	N/A	Deciphering epigenetic influence of curcumin on histone signatures in breast cancer using 3D network
Fast-Part：用于生物序列分析的快速且准确的数据分区工具	Ahmed, S.	PDF	N/A	Fast-Part: Fast and Accurate Data Partitioning for Biological Sequence Analysis
评估肺炎链球菌中假定小RNA的保守性和目标	Eichelman, M. C.	PDF	N/A	Assessing the conservation and targets of putative sRNAs in Streptococcus pneumoniae
IMMClock揭示了免疫老化和T细胞功能在单细胞分辨率下的表现	Schmidt, Y. G.	PDF	N/A	IMMClock reveals immune aging and T cell function at single-cell resolution
大规模定量交联与质谱技术为细胞器、细胞和组织内的蛋白质构象可塑性提供了新的见解	Keller, A.	PDF	N/A	Large-Scale Quantitative Cross-Linking and Mass Spectrometry Provides New Insight on Protein Conformational Plasticity within Organelles, Cells, and Tissues
NERVE 2.0：通过人工智能和用户友好的网络界面提升新增强反向疫苗学环境	Conte, A.	PDF	N/A	NERVE 2.0: boosting the New Enhanced Reverse Vaccinology Environment via artificial intelligence and a user-friendly web interface
使用InMoose进行差异表达分析，InMoose是Python中的集成多组学开源环境	Colange, M.	PDF	N/A	Differential Expression Analysis with InMoose, the Integrated Multi-Omic Open-Source Environment in Python
通过X射线散射和坐标建模对细菌微区室壳体的结构表征：细胞质蛋白偶然捕获的证据	Zuo, X.	PDF	N/A	Structure Characterization of Bacterial Microcompartment Shells via X-ray Scattering and Coordinate Modeling: Evidence for adventitious capture of cytoplasmic proteins
肿瘤球体对荧光纳米金刚石的摄取受限于质量密度：一种四维光片检测法	Niora, M.	PDF	N/A	Tumor Spheroid Uptake of Fluorescent Nanodiamonds is Limited by Mass Density: a 4D Light-Sheet Assay
在三维空间中量化单个纤维尺度的细胞牵引力：基于可变形光聚合纤维阵列的新方法	Ucla, P.	PDF	N/A	Quantifying Cell Traction Forces at the Individual Fiber Scale in 3D: A Novel Approach Based on Deformable Photopolymerized Fiber Arrays
全片基质成像显示，密集纤维基质是II期结肠癌复发的高风险因素	Ravensbergen, C.	PDF	N/A	Whole-Slide ECM Imaging Reveals Dense Fibrous Matrix as a High-Risk Factor for Recurrence in Stage II Colon Cancer
发育阶段与细胞背景决定Ezh2Y641F突变在造血中的致癌与分子结果	Zimmerman, S. M.	PDF	N/A	Developmental Stage and Cellular Context Determine Oncogenic and Molecular Outcomes of Ezh2Y641F Mutation in Hematopoiesis
癌症细胞中p53对SOX2的转录抑制调控细胞身份和迁移	Lado-Fernandez, P.	PDF	N/A	Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration
ecPath 通过组织病理学图像检测肿瘤中的ecDNA	Choudhury, M.	PDF	N/A	ecPath detects ecDNA in tumors from histopathology images
鉴定Ephrin B型受体4为组织纤维化的关键介质	Wu, B. R.-L.	PDF	N/A	Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis
成纤维细胞衍生的骨糖蛋白促进上皮细胞修复	van der Koog, L.	PDF	N/A	Fibroblast-derived osteoglycin promotes epithelial cell repair
腓肠肌俯卧撑对糖尿病前期患者血糖耐受性的影响	Elek, D.	PDF	N/A	The effects of soleus push up on glucose tolerance among individuals with prediabetes
源自生物衰老组织学特征的组织时钟能够从血液中进行组织特异性衰老预测	Abila, E.	PDF	N/A	Tissue clocks derived from histological signatures of biological aging enable tissue-specific aging predictions from blood
OPN5和TRPV4在小鼠角膜上皮的内源性光敏感性中起作用。	Lapajne, L.	PDF	N/A	OPN5 and TRPV4 subserve intrinsic photosensitivity in mouse corneal epithelium
对哺乳动物分泌途径的重建揭示了调控抗体生产的机制	Masson, H.	PDF	N/A	A reconstruction of the mammalian secretory pathway identifies mechanisms regulating antibody production
一种新颖而简单的操作方法大大提高了大鼠肝脏移植的成功率。	Chen, Y.	PDF	N/A	A novel and simple maneuver greatly improves rat liver transplantation
单细胞图谱的描绘为川崎病冠状动脉病变的发展提供了新的见解：坏与好的信号分子	Lin, Q.	PDF	N/A	Delineation of Single-cell Altas Provides New Insights for Development of Coronary Artery Lesions in Kawasaki Disease: Bad and Good Signaling Molecules
规范的Notch2信号调节铁回收巨噬细胞的发育和铁稳态	Schroth, F. N.	PDF	N/A	Canonical Notch2 Signaling Regulates the Development of Iron-recycling Macrophages and Iron Homeostasis
木制奶酪熟化板上的微生物群是产生抗李斯特菌单核细胞增生菌的抗菌细菌的丰富来源。	Chen, Y.	PDF	N/A	The microbiota of wooden cheese ripening boards is a rich source of antimicrobial-producing bacteria against Listeria monocytogenes
综合蛋白质组和脂质组分析将OCIAD1定位于线粒体与过氧化物酶体的交汇处，平衡脂质代谢	Linke, V.	PDF	N/A	Integrated proteome and lipidome analyses place OCIAD1 at mitochondria-peroxisome intersection balancing lipid metabolism
抑制酸性神经酰胺酶作为一种治疗尼曼-皮克C病的治疗策略	Haynes, I.	PDF	N/A	Inhibition of acid ceramidase as a therapeutic strategy for Niemann-Pick C disease
通过两亲性螺旋在内核膜上感知脂质松动的参数	Lee, S.	PDF	N/A	Parameters for sensing lipid loosening at the inner nuclear membrane by amphipathic helices
在颗石藻生物矿化过程中富钙区室的动态变化	Triccas, A.	PDF	N/A	Dynamic change of calcium-rich compartments during coccolithophore biomineralization
ATF4通过调节线粒体功能障碍、线粒体自噬和自噬，在Fuchs营养不良症中慢性内质网应激下促进角膜内皮细胞凋亡。	Qureshi, S.	PDF	N/A	ATF4 regulates mitochondrial dysfunction, mitophagy, and autophagy, contributing to corneal endothelial apoptosis under chronic ER stress in Fuchs dystrophy
TUDCA通过调节药物生物利用度来调控酿酒酵母对急性内质网应激的抗性	Chadwick, S. R.	PDF	N/A	TUDCA modulates drug bioavailability to regulate resistance to acute ER stress in Saccharomyces cerevisiae
PCMD-1稳定了PCM支架并促进了中心粒的分离	Schreiner, A.	PDF	N/A	PCMD-1 stabilizes the PCM scaffold and facilitates centriole separation
人工结构中优化的凹槽设计显著提高了珊瑚的定居和生存率	Reichert, J.	PDF	N/A	Optimized recess design in artificial structures dramatically enhances coral settlement and survival
评估数据驱动的捕食者-猎物模型的保真度：动力系统分析	Frank, A.-S.	PDF	N/A	Evaluating the Fidelity of Data-Driven Predator-Prey Models: A Dynamical Systems Analysis
时间至关重要：H5N1病毒在奶牛场的控制效果受限于其快速传播。	DeWitt, M. E.	PDF	N/A	Time is of the essence: effectiveness of dairy farm control of H5N1 is limited by fast spread
探索珠穆朗玛峰绒布河流域冰川补给河流沉积物中的产甲烷古菌及其热响应	Ma, W.	PDF	N/A	Exploring methanogenic archaea and their thermal responses in the glacier-fed stream sediments of Rongbuk River Basin, Mt. Everest
澳大利亚无刺蜜蜂的视觉生理学	Penmetcha, B.	PDF	N/A	Visual physiology of Australian stingless bees
泛癌种有丝分裂DNA完整性检验点蛋白激酶的遗传特征	Rasteh, A. M.	PDF	N/A	Pan-Cancer Genetic Profiles of Mitotic DNA Integrity Checkpoint Protein Kinases
LIN-35和DREAM复合体促进温度应激诱导的秀丽隐杆线虫生殖细胞凋亡和胞质流动增加。	Petrella, L. N.	PDF	N/A	LIN-35 and the DREAM complex promote temperature stress induced increases in germline apoptosis and cytoplasmic streaming in C. elegans
类固醇受体辅助加载调控前列腺癌细胞的转录反应	Hiltunen, J.	PDF	N/A	Steroid receptor-assisted loading modulates transcriptional responses in prostate cancer cells
不确定性感知基因组深度学习与知识蒸馏	Zhou, J.	PDF	N/A	Uncertainty-aware genomic deep learning with knowledge distillation
Illumina Complete Long Read Ass测定法能够从人类肠道宏基因组中生成连续的细菌基因组。	Maghini, D. G.	PDF	N/A	Illumina Complete Long Read Assay yields contiguous bacterial genomes from human gut metagenomes
可点击的聚乙二醇-降冰片烯微凝胶支持悬浮生物打印和微血管组装	Zhang, I. W.	PDF	N/A	Clickable PEG-norbornene microgels support suspension bioprinting and microvascular assembly
利用蛋白质结构图嵌入预测错义变异的致病性	Danner, M.	PDF	N/A	Utilizing protein structure graph embeddings to predict the pathogenicity of missense variants
使用穷尽蛋白质搜索和Alphafold2进行蛋白质搜索漂移的特征化	Buchan, D. W.	PDF	N/A	Characterising Protein Search Drift using exhaustive protein search and Alphafold2
miRBench：一个全面的微RNA结合位点预测训练和基准测试数据集	Sammut, S.	PDF	N/A	miRBench: A Comprehensive microRNA Binding Site Prediction Training and Benchmarking Dataset
阿努比斯：一种利用随机森林分类法对古代蛋白质进行多层次鉴定的方法	Chiang, Y.	PDF	N/A	Anubis: a multi-level authentication scale for ancient proteins using random forest classification
STABIX：基于摘要统计的全基因组关联分析索引与压缩	Schneider, K.	PDF	N/A	STABIX: Summary statistic-based GWAS indexing and compression
TSniffer：在RNA-seq数据中无偏倚地从头鉴定RNA编辑位点并量化编辑活性	Herrmann, M.	PDF	N/A	TSniffer: Unbiased de novo identification of RNA editing sites and quantification of editing activity in RNA-seq data
语言模型引导的未知代谢物预测与发现	Qiang, H.	PDF	N/A	Language model-guided anticipation and discovery of unknown metabolites
CLUEY 能够从单细胞组学数据中实现知识引导的聚类和细胞类型检测。	Kim, D.	PDF	N/A	CLUEY enables knowledge-guided clustering and cell type detection from single-cell omics data
构建基于单细胞转录组的坐标系统用于细胞ID识别的SURE方法	Zeng, F.	PDF	N/A	Building a single cell transcriptome-based coordinate system for cell ID with SURE
脂质组成在体外和体内系统之间的铁死亡敏感性上存在差异	Park, V. S.	PDF	N/A	Lipid composition differentiates ferroptosis sensitivity between in vitro and in vivo systems
过氧化物酶表达在肿瘤内毛细血管和邻近透明细胞肾细胞癌的近端小管细胞中增加。	Pestana e Silva, R. N.	PDF	N/A	Peroxidasin expression is increased in intratumoural capillaries and in proximal tubular cells adjacent to clear cell renal cell carcinoma.
司美格鲁肽诱导的体重减轻改善了骨骼肌线粒体能量效率	Choi, R. H.	PDF	N/A	Semaglutide-induced weight loss improves mitochondrial energy efficiency in skeletal muscle
数字免疫优化血凝素与纳米笼插接展示技术激发广泛中和的全H5流感亚型疫苗反应	Huang, C. Q.	PDF	N/A	Digitally immune optimised haemagglutinin with nanocage plug-and-display elicits broadly neutralising pan-H5 influenza subtype vaccine responses
抗HIV-1 B细胞抗原受体信号传导与结构	Thakur, B.	PDF	N/A	Anti-HIV-1 B cell antigen receptor signaling and structure
炎症相关单核细胞表达ACOD1以遏制炎症行为在IBD和实验性结肠炎中	Jones, G.-R.	PDF	N/A	Inflammation-associated monocytes express ACOD1 to curtail inflammatory behaviour in IBD and experimental colitis
血吸虫食道腺因子MEG-8.2驱动宿主细胞裂解并与其免疫蛋白相互作用	Yadav, P.	PDF	N/A	Schistosome esophageal gland factor MEG-8.2 drives host cell lysis and interacts with host immune proteins
衣原体质粒编码蛋白Pgp2是一种复制起始蛋白，具有独特的β-发夹结构，对于与迭代子结合及质粒复制至关重要。	Wan, D.	PDF	N/A	Chlamydia plasmid-encoded protein Pgp2 is a replication initiator with a unique beta-hairpin necessary for iteron-binding and plasmid replication
利用蛋白质语言模型进行基于结构的发现，以获得高效且稳定的PET水解酶	Wu, B.	PDF	N/A	Harnessing Protein Language Model for Structure-Based Discovery of Highly Efficient and Robust PET Hydrolases
新型CRITR-seq方法揭示了流感转录受到NELF的调控，并且是引发干扰素反应的关键事件。	Vicary, A. C.	PDF	N/A	Novel CRITR-seq approach reveals influenza transcription is modulated by NELF and is a key event precipitating an interferon response
维生素E、高密度脂蛋白及B型1类清道夫受体对脂质氧化与铁死亡的生理调节作用	Rink, J. S.	PDF	N/A	Physiologic Regulation of Lipid Oxidation and Ferroptosis By Vitamin E, High-Density Lipoprotein, and Scavenger Receptor Class B Type 1
一类新型变构葡萄糖脑苷脂酶β1校正剂，可减轻细胞应激并增强溶酶体功能	Fregno, I.	PDF	N/A	A novel class of allosteric glucosylceramidase beta 1 correctors that reduce cellular stress and enhance lysosomal function
城市树木多样性促进了鸟类食虫性，尽管随着城市化进程，鸟类多样性有所下降。	Schille, L.	PDF	N/A	Urban tree diversity fosters bird insectivory despite a loss in bird diversity with urbanization
区分果蝇中轻度、重度及非典型过氧化物酶体生成障碍的PEX基因变异严重程度	Gomez, V. A.	PDF	N/A	Distinguishing PEX gene variant severity for mild, severe, and atypical peroxisome biogenesis disorders in Drosophila
PRC1和CTCF介导的从预备状态到活跃状态的染色质环转变驱动双价基因激活	Hanafiah, A.	PDF	N/A	PRC1 and CTCF-Mediated Transition from Poised to Active Chromatin Loops Drives Bivalent Gene Activation
mTORC1在溶酶体膜上整合生长因子和营养信号的结构基础	Cui, Z.	PDF	N/A	Structural basis for growth factor and nutrient signal integration on the lysosomal membrane by mTORC1
受缺陷的SNARE拉链或硬质脂质脂肪酸组成限制的膜融合反应对Sec17、Sec18和腺苷酸有不同的需求。	Lopes, K.	PDF	N/A	Membrane fusion reactions limited by defective SNARE zippering or stiff lipid fatty acyl composition have distinct requirements for Sec17, Sec18, and adenine nucleotide
炎症巨噬细胞分泌的细胞因子调节了水凝胶生物材料上瓣膜间质细胞的性别差异	Felix Velez, N. E.	PDF	N/A	Secreted cytokines from inflammatory macrophages modulate sex differences in valvular interstitial cells on hydrogel biomaterials
Orthrus：一种基于人工智能、云端就绪且开源的混合方法，用于元蛋白质组学研究	Chiang, Y.	PDF	N/A	Orthrus: an AI-powered, cloud-ready, and open-source hybrid approach for metaproteomics
从Hi-C数据解读跨物种的三维基因组结构	Shkolikov, A.	PDF	N/A	Deciphering the 3D genome organization across species from Hi-C data
识别相互作用神经退行性蛋白质之间的铜配位环境：使用14N/15N同位素标记的脉冲EPR新方法	Smart, A.	PDF	N/A	Identifying the Copper Coordination Environment Between Interacting Neurodegenerative Proteins: A New Approach Using Pulsed EPR with 14N/15N Isotopic Labelling
上皮细胞中HKDC1的缺失减缓了细胞增殖，并损害了肿瘤性上皮细胞的线粒体功能，从而保护小鼠免受肠道癌变的影响。	Jaerke, L.	PDF	N/A	Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis in mice
过敏性肺炎中的T细胞受体共享	Sendama, W.	PDF	N/A	T cell receptor sharing in hypersensitivity pneumonitis
替代性cGAS信号传导促进单纯疱疹性脑炎	Shmuel-Galia, L.	PDF	N/A	Alternative cGAS signaling promotes Herpes simplex encephalitis
转录组学预测夜间人工光照（ALAN）对适应性的影响：夜间光照改变了摇蚊（Chironomus riparius，双翅目：摇蚊科）的基因表达模式，并对适应性成分产生负面影响	Eberhardt, L.	PDF	N/A	Transcriptomics predicts Artificial Light at Night's (ALAN) impact on fitness: nightly illumination alters gene expression pattern and negatively affects fitness components in the midge Chironomus riparius (Diptera:Chironomidae)
多聚核糖体和mRNA调控真核细胞胞质的生物物理特性	Gade, V. R.	PDF	N/A	Polysomes and mRNA control the biophysical properties of the eukaryotic cytoplasm
无序玻璃纳米线基底通过光学衍射断层成像揭示了类似体内星形胶质细胞的形态	Anantha, P.	PDF	N/A	Disordered glass nanowire substrates produce in vivo-like astrocyte morphology revealed by optical diffraction tomography
TSSK同源物调控按蚊精氨酸和斯氏按蚊睾丸特异性基因的表达	Meghwanshi, K. K.	PDF	N/A	TSSK homologue regulates the expression of protamine and mosquito testes specific genes in Anopheles stephensi
泛基因组参考序列改善了从肿瘤测序数据中生物标志物的估计	Arslan, E.	PDF	N/A	Pangenome References Improve Biomarker Estimation from Tumor Sequencing Data
使用深度学习从基因表达预测泛癌药物敏感性	Ocasio, B. A.	PDF	N/A	Pan-Cancer Drug Sensitivity Prediction from Gene Expression using Deep Learning
预测的细胞粘附分子MPZL3的丢失促进了卵巢癌中的上皮-间质转化和化学抗性	Cheng, Y.-Y.	PDF	N/A	Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancer
# BioRxiv 2024-11-14 Papers

标题	作者	PDF链接	代码仓库	Title
从单细胞的动力学和几何结构中学习细胞特异性网络	Zhang, S. Y.	PDF	N/A	Learning cell-specific networks from dynamics and geometry of single cells
计算机模拟兔眼和人眼中玻璃体内注射贝伐单抗后的药物分布	Chowdhury, J. M.	PDF	N/A	Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes
用等效电路解释神经可塑性：一种机制性视角	Nilsson, M. N. P.	PDF	N/A	Explaining neuroplasticity using equivalent circuits: A mechanistic perspective
SNP分配用于估计遗传力（SAFE-h2）：一种用于探索表型基因组起源的工具，用于使用仅加性等位基因效应或加性和非加性等位基因效应估计SNP遗传力	Darbani, B.	PDF	N/A	SNP Allocation For Estimating Heritability (SAFE-h2): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects
通过高分辨率冷冻电镜结构揭示的APC/C的新结构特征：apo-APC/C和APC/C CDH1:EMI1复合物的结构	Hoefler, A.	PDF	N/A	New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C CDH1:EMI1 complex
致幻剂5-HT2A受体激动作用：神经元特征与神经血管耦合的改变。	Padawer-Curry, J. A.	PDF	N/A	Psychedelic 5-HT2A receptor agonism: neuronal signatures and altered neurovascular coupling.
海马中三种中间神经元群体的绝对数量及所有GABA能突触的绝对数量	Takacs, V.	PDF	N/A	Absolute number of three populations of interneurons and all GABAergic synapses in the human hippocampus
膜电位介导细胞对机械压力的响应	Mukherjee, A.	PDF	N/A	Membrane potential mediates the cellular response to mechanical pressure
粘附斑衍生的液-液相分离调控mRNA翻译	Kumar, A.	PDF	N/A	Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation
TRPV1和TRPM2在温暖温度检测中的不同作用	Abd El Hay, M. Y.	PDF	N/A	Diverging roles of TRPV1 and TRPM2 in warm-temperature detection
无细胞优化生产原卟啉IX	Garcia, D. C.	PDF	N/A	Cell-Free Optimized Production of Protoporphyrin IX
短链脂肪酸代谢产物丙酸和丁酸是独特的表观遗传调控因子，连接着饮食、代谢和基因表达。	Nshanian, M.	PDF	N/A	Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression
基于逻辑的生物网络建模与Netflux	Clark, A. P.	PDF	N/A	Logic-based modeling of biological networks with Netflux
利用大型语言模型揭示人脑中的多层次和多模态语义表征	Nakagi, Y.	PDF	N/A	Unveiling Multi-level and Multi-modal Semantic Representations in the Human Brain using Large Language Models
抗漂移姿态追踪器（ADPT）：一种基于Transformer的网络，用于跨物种的稳健动物姿态估计	Tang, G.	PDF	N/A	Anti-drift pose tracker (ADPT): A transformer-based network for robust animal pose estimation cross-species
所有细菌基因组 - 已组装、可用且可搜索的细菌基因组数据库	Hunt, M.	PDF	N/A	AllTheBacteria - all bacterial genomes assembled, available and searchable
患者来源的ccRCC类器官单细胞中异质性和新型转录本的表达	Karakulak, T.	PDF	N/A	Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids
在变暖和干燥的气候条件下，热带干旱森林树木的叶部和生殖物候的量和时间变化	Lai, H. R.	PDF	N/A	Changes in quantity and timing of foliar and reproductive phenology of tropical dry-forest trees under a warming and drying climate
在主动舔食的小鼠中，皮层对味觉和温度信号的编码	Nash, A. N.	PDF	N/A	Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice
受损的卵黄囊NAD代谢会破坏小鼠胚胎发育，这与人类出生缺陷有关。	Bozon, K.	PDF	N/A	Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects
一个用于抗体序列理解的生成基础模型	Barton, J.	PDF	N/A	A generative foundation model for antibody sequence understanding
比较群体基因组学揭示了西南太平洋热液喷口区一致的次级缝合带	Tran Lu Y, A.	PDF	N/A	Comparative population genomics unveils congruent secondary suture zone in Southwest Pacific Hydrothermal Vents
iHDSel软件：利用Price方程和群体稳定性指数检测与选择性清除相符的基因组模式。以SARS-CoV-2为例。	Carvajal-Rodriguez, A.	PDF	N/A	iHDSel software: The Price equation and the population stability index to detect genomic patterns compatible with selective sweeps. An example with SARS-CoV-2.
对秀丽隐杆线虫中Smad和Schnurri转录因子的全基因组分析显示了它们广泛的相互作用，并在胶原蛋白分泌中发挥功能。	Vora, M.	PDF	N/A	Genome-wide analysis of Smad and Schnurri transcription factors in C. elegans demonstrates widespread interaction and a function in collagen secretion
开源自动化通用高内涵多重荧光RNA原位分析（AURA）协议	Descarpentrie, J.	PDF	N/A	Protocol for open-source Automated Universal high-content multiplex fluorescence for RNA in situ Analysis (AURA)
草莓COP9信号体FvCSN5A通过促进多胺氧化酶FvPAO5的降解，调控植物发育和果实成熟，从而控制多胺和H2O2的稳态。	Huang, Y.	PDF	N/A	Strawberry COP9 signalosome FvCSN5A regulates plant development and fruit ripening by facilitating polyamine oxidase FvPAO5 degradation to control polyamine and H2O2 homeostasis
在小鼠中，绿茶化合物在饮用绿茶后的血浆中出现的情况受到肠道微生物群的调节。	Sterrett, J. D.	PDF	N/A	Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice
空间变异竞争导致植物适应性和分布对环境梯度的反应不匹配	Hayashi, K. T.	PDF	N/A	Spatially variable competition contributes to mismatched responses of plant fitness and occurrence to environmental gradients
来自韩国都湖组（中新世）的新鲣鱼标本（属名Auxis）	Suh, D.	PDF	N/A	A new tuna specimen (Genus Auxis) from the Duho Formation (Miocene) of South Korea
细胞类型特异性调控TOR介导的微管乙酰化预测Yki丢失诱导的果蝇鳞状细胞癌	Bhattacharya, R.	PDF	N/A	Cell-Type-Specific Regulation of TOR-Mediated Microtubule Acetylation Predicts Yki Loss-Induced Squamous Cell Carcinoma in Drosophila
是我还是火车在动？人类在平衡控制中通过一种非线性反馈机制来解决感官冲突。	Asslaender, L.	PDF	N/A	Is it me or the train moving? Humans resolve sensory conflicts with a nonlinear feedback mechanism in balance control
操作性酒精自我给药以一种驱动药物强化特性的方式，靶向含有GluA2的AMPAR表达和伏隔核中的突触活动。	Faccidomo, S.	PDF	N/A	Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug
不活动介导的分子适应：从体力活动减少的临床前模型中获得的见解	Meyer, A.	PDF	N/A	Inactivity-mediated molecular adaptations: insights from a pre-clinical model of physical activity reduction
C57BL/6J小鼠在家庭笼中饮用乙醇和操作性自我给药方面的性别差异，但谷氨酸AMPAR活性调节的等效性	Faccidomo, S.	PDF	N/A	Sex Differences in Home-Cage Ethanol Drinking and Operant Self-Administration in C57BL/6J Mice but Equivalent Regulation by Glutamate AMPAR Activity
利用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层特定层区域边界图	Autio, J. A.	PDF	N/A	Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI
通过完全自主的HABITS系统实现新颖且优化的鼠标行为：家庭笼辅助行为创新与测试系统	Yu, B.	PDF	N/A	Novel and optimized mouse behavior enabled by fully autonomous HABITS: Home-cage Assisted Behavioral Innovation and Testing System
Pannexin-2 缺陷破坏视觉通路并导致斑马鱼眼部缺陷	Shanbhag, R.	PDF	N/A	Pannexin-2 deficiency disrupts visual pathways and leads to ocular defects in zebrafish
血液培养物中含有遗传多样性的白色念珠菌菌株，这些菌株在棘白菌素耐药性和毒力方面可能存在差异。	Fleres, G.	PDF	N/A	Blood cultures contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and virulence
高度多孔的颗粒状水凝胶，通过静电纺丝水凝胶纤维增强，以实现长期稳定性	Whitewolf, J.	PDF	N/A	Highly porous granular hydrogels reinforced by electrospun hydrogel fibers for long-term stability
化石记录中稀疏时间序列的反应规范适应度峰值追踪	Ergon, R.	PDF	N/A	Reaction norm fitness peaks tracking applied on sparse time series in the fossil record
岛屿人口统计学：哥特兰岛标志性金雕的繁殖动态及驱动因素	Singh, N. J.	PDF	N/A	Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles
无标记鸟枪法蛋白质组学中监测宿主细胞蛋白的MS/MS搜索算法比较分析，采用捕获离子淌度和ddaPASEF技术	Khalil, S.	PDF	N/A	Comparative analysis of MS/MS search algorithms in label-free shotgun proteomics for monitoring host-cell proteins using trapped ion mobility and ddaPASEF
雌蛾将植物的声发射纳入其产卵决策中	Seltzer, R.	PDF	N/A	Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision
新生转录本O-MAP揭示了由RBM20和TTN RNA构建的单基因位点亚核区室的分子结构	Kania, E. E.	PDF	N/A	Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA
抑郁症和焦虑症中基底前脑对内在脑网络的调控改变	Jamieson, A. J.	PDF	N/A	Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders
在人类和小鼠胰岛素中，一种翻译后将半胱氨酸转化为丝氨酸的转变，产生了一种糖尿病新表位。	Srivastava, N.	PDF	N/A	A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope
资源环境塑造了人类阴道微生物群的组成和稳定性。	Kamiya, T.	PDF	N/A	Resource landscape shapes the composition and stability of the human vaginal microbiota
ER Ca2+水平通过调节L型Ca2+通道活性来控制神经调质的分泌。	Hoogstraaten, R. I.	PDF	N/A	ER Ca2+-levels control neuromodulator secretion by regulating L-type Ca2+-channel activity
在一年的时间里，孟加拉国各地的霍乱弧菌谱系和泛基因组多样性存在地理差异。	Qin, C.	PDF	N/A	Vibrio cholerae lineage and pangenome diversity varies geographically across Bangladesh over one year
有丝分裂CIP2A-TOPBP1轴促进有丝分裂途径在MiDAS和MMEJ之间的选择。	Martin, P. R.	PDF	N/A	The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ
重度抑郁症外周血单个核细胞神经免疫网络中突触相关基因的失调	Adri, A.	PDF	N/A	Dysregulation of synaptic-related genes within neuroimmune networks of peripheral blood mononuclear cells in major depressive disorder
比较用于预测急性髓系白血病患者突变状态的机器学习模型，使用RNA测序数据	Silva, R.	PDF	N/A	Comparing machine learning models for predicting mutation status in Acute Myeloid Leukemia patients using RNA-seq data
加拿大早期职业健康研究人员特征及COVID-19疫情期间的职业倦怠经历	Hewko, S.	PDF	N/A	Characteristics of early career health researchers and experiences of burnout during the COVID-19 pandemic in Canada
我们是意识的传感器！关于睡眠中的觉醒如何影响梦境回忆的回顾与分析。	Stucky, B.	PDF	N/A	We are the sensors of consciousness! A review and analysis on how awakenings during sleep influence dream recall.
坦桑尼亚南部伊法卡拉-卢皮罗-曼古拉野生动物管理区的利益相关者对其有效性的看法	Tarimo, L. J.	PDF	N/A	Stakeholder perspectives on the effectiveness of the Ifakara-Lupiro-Mang'ula Wildlife Management Area in Southern Tanzania
对GWAS汇总统计数据的稀疏矩阵分解，能够稳健地处理样本共享问题，从而提高对具有多样遗传结构的因素的检测和解释能力。	Omdahl, A. R.	PDF	N/A	Sparse matrix factorization of GWAS summary statistics robust to sample sharing improves detection and interpretation of factors with diverse genetic architectures
量化颅骨整骨手法对阿尔茨海默病野生型和转基因大鼠模型的影响	Hines, D.	PDF	N/A	Effect of quantified cranial osteopathic manipulation on wild type and transgenic rat models of Alzheimer's disease
经典三叉神经痛患者的脑老化	Cruz-Almeida, Y.	PDF	N/A	Brain Aging Among Individuals with Classical Trigeminal Neuralgia
在实体瘤基质中异常表达的X型胶原蛋白与上皮-间质转化、免疫抑制和促转移通路、骨髓基质细胞特征以及不良的生存预后相关。	Famili-Youth, E. H. H.	PDF	N/A	Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis
饮食和非酶氧化固醇在子痫前期胎盘中的积累：对妊娠并发症中胆固醇动态的见解	Zou, L.	PDF	N/A	Accumulation of Dietary and Non-Enzymatic Oxysterols in Preeclamptic Placentas: Insights into Cholesterol Dynamics in Pregnancy Complications
母亲运动方式对婴儿脐带血蛋白质组的影响	Jevtovic, F.	PDF	N/A	Effects of maternal exercise modes on infant cord blood proteome
小窝蛋白-1和水通道蛋白-4作为遗传性脑淀粉样血管病中纤维蛋白原驱动脑血管病理的介质	Singh, V.	PDF	N/A	Caveolin-1 and Aquaporin-4 as Mediators of Fibrinogen-Driven Cerebrovascular Pathology in Hereditary Cerebral Amyloid Angiopathy
使用高灵敏度磷脂酰丝氨酸结合试剂在体内评估细胞外囊泡的周转	Flaskamp, L.	PDF	N/A	Assessing Extracellular Vesicle Turnover In vivo Using Highly Sensitive Phosphatidylserine-Binding Reagents
在有鳞目深系谱中，核与线粒体氧化磷酸化复合体亚基的趋同进化证据	Wallnoefer, O.	PDF	N/A	Evidence of convergent evolution in the nuclear and mitochondrial OXPHOS subunits across the deep lineages of Squamata
通过张量分解重构RNA-断层扫描转录组的三维空间结构	Song, T.	PDF	N/A	Reconstructing 3D Spatial Structures of RNA-Tomography Transcriptomes by Tensor Factorization
全蛋白质组反向分子对接揭示叶酸受体作为PFAS诱导神经发育毒性的介质	Kong, A. X.	PDF	N/A	Proteome-wide reverse molecular docking reveals folic acid receptor as a mediator of PFAS-induced neurodevelopmental toxicity
调控Koisio技术生产的流体对血管外膜间质液流动的影响及其通过输送艾司洛尔对心率的作用	Li, B.	PDF	N/A	Regulating of Koisio technology-produced fluid on Vascular Adventitial Interstitial Fluid flow and its Effect on heart rate by delivering Esmolol
蛋白质-蛋白质相互作用是遗传相互作用网络中上位性的主要来源	Castellanos-Girouard, X.	PDF	N/A	Protein-protein interaction is a major source of epistasis in genetic interaction networks
坏死性脑膜脑炎中的星形胶质细胞功能障碍、脱髓鞘和结节性炎症	Hernandez, S. I.	PDF	N/A	Astroglial Dysfunction, Demyelination and Nodular inflammation in Necrotizing Meningoencephalitis
在竞争性生态系统中多重稳定平衡的结构	Taylor, W.	PDF	N/A	On the structure of multiple stable equilibria in competitive ecological systems
scPrediXcan将深度学习和单细胞数据的进展整合到一个强大的细胞类型特异性转录组关联研究框架中。	Zhou, Y.	PDF	N/A	scPrediXcan integrates advances in deep learning and single-cell data into a powerful cell-type-specific transcriptome-wide association study framework
底物和产物选择性尼龙水解酶的鉴定与表征	Drufva, E.	PDF	N/A	Identification and characterization of substrate- and product-selective nylon hydrolases
金属水解酶的计算设计	Kim, D.	PDF	N/A	Computational Design of Metallohydrolases
大鼠颞下颌关节中锌特异性髁突区的硫物种	Lee, B. H.	PDF	N/A	Sulfur-species in Zinc-specific Condylar Zones of a Rat Temporomandibular Joint
PYR1生物传感器驱动的克鲁维酵母基因组范围CRISPR筛选，以提高单萜类化合物生产	Robertson, N. R.	PDF	N/A	PYR1 biosensor-driven genome-wide CRISPR screens for improved monoterpenoid production in Kluyveromyces marxianus
心脏组织中早期后去极化驱动的心律失常机制	Stein, J.	PDF	N/A	Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue
快速反应特质在感觉运动皮层中的Mu和Beta节律效应在提示前和运动执行期间表现出双重分离	Kamali, S.	PDF	N/A	Mu and beta power effects of fast response trait double dissociate during precue and movement execution in the sensorimotor cortex
通信子空间与人工神经网络的训练相一致	Poggi, P. G.	PDF	N/A	Communication subspaces align with training in ANNs
紫外线诱导的DNA修复机制及其对大肠杆菌突变性和培养能力的影响	Ghosh, S.	PDF	N/A	UV-Induced DNA Repair Mechanisms and Their Effects on Mutagenesis and Culturability in Escherichia coli
布氏锥虫的糖体ATP依赖性磷酸果糖激酶在体内类似条件下，在细胞内以糖异生方向进行操作。	Plazolles, N.	PDF	N/A	The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates in the gluconeogenic direction in cellulo under in vivo-like conditions
Mcm3中一个必需的核定位序列的序列特异性	Wang, Z.	PDF	N/A	Sequence specificity of an essential nuclear localization sequence in Mcm3
生物膜形成和生态位适应在塑造远距离运输的尘埃微生物群落中起着基础性作用。	Lang-Yona, N.	PDF	N/A	Biofilm Formation and Niche Adaptation Play Fundamental Role in Shaping Long-Distance Transported Dust Microbial Community
自然发生的、菌株特异性的鲍曼不动杆菌IV型菌毛回缩缺陷促进了生物膜的形成	Yu, Y.	PDF	N/A	Naturally-occurring, strain-specific defects in the retraction of Acinetobacter baumannii type IV pili promote biofilm formation
揭示可可病原菌Moniliophthora perniciosa对嘧菌酯抗性的新机制	do Prado, P. F. V.	PDF	N/A	Unveiling novel mechanisms of strobilurin resistance in the cacao pathogen Moniliophthora perniciosa
5500年前贝加尔湖狩猎采集者的致命瘟疫爆发	Macleod, R.	PDF	N/A	Lethal Plague Outbreaks in Lake Baikal Hunter-gatherers 5500 Years Ago
基于活动的增强型碱基编辑器突变扫描的选择	Kaplan, E. G.	PDF	N/A	Activity-based selection for enhanced base editor mutational scanning
使用MxP(R) Quant 500试剂盒对人血和啮齿动物血液进行标准化代谢组学和脂质组学分析的实验室间比较	Zararsiz, G. E.	PDF	N/A	Interlaboratory comparison of standardised metabolomics and lipidomics analyses in human and rodent blood using the MxP(R) Quant 500 kit
通过着丝粒DNA序列增强的力传递至内着丝粒	Miedlar, E.	PDF	N/A	Force transmission through the inner kinetochore is enhanced by centromeric DNA sequences
基于机制的方法在设计针对无义突变疾病的个性化联合疗法中的应用	Bhat, S.	PDF	N/A	Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases
动物编码的非核糖体途径合成bursatellin类似物。	Schmidt, E. W.	PDF	N/A	Animal-encoded nonribosomal pathway to bursatellin analogs.
RhoA通过其EF手结构域别构激活磷脂酶Cε	Ohri, V.	PDF	N/A	RhoA Allosterically Activates Phospholipase Cε via its EF Hands
杨树：一个系统发育学分析流程	Krishnakumar, R.	PDF	N/A	Poplar: A Phylogenetics Pipeline
通过基于同源性和表示的分层聚类探索大型蛋白质序列空间	Chen, J. Z.	PDF	N/A	Exploring large protein sequence space through homology- and representation-based hierarchical clustering
利用大型语言模型增强基因集富集分析	Zhu, J.	PDF	N/A	Enhancing Gene Set Overrepresentation Analysis with Large Language Models
在科学会议上无法理解的图表	Faulkes, Z.	PDF	N/A	Uninterpretable graphs at a scientific conference
外周CGRP参与偏头痛的脑电网络活动	Johnson, M. S.	PDF	N/A	Peripheral CGRP engages brain-wide electrical network activity of migraine
社交焦虑改变了电影观看期间心智理论激活和跨受试者神经变异性的情况	Mangnus, M.	PDF	N/A	Social Anxiety Alters Theory of Mind Activation and Intersubject Neural Variability During Movie Viewing
下调星形胶质细胞C3的产生可缓解tau病模型中的神经元线粒体功能障碍	Lei, C.	PDF	N/A	Downregulation of astrocytic C3 production alleviates neuronal mitochondrial dysfunction in tauopathy models
学习后的休息有助于记忆巩固，并能逆转3xTg-AD小鼠在新环境中空间重定向能力的损伤。	Stimmell, A. C.	PDF	N/A	Resting After Learning Facilitates Memory Consolidation and Reverses Spatial Reorientation Impairments in 'New Surroundings' in 3xTg-AD Mice
FreeSurfer版本对帕金森病结构神经影像分析的影响	Sokolowski, A.	PDF	N/A	The impact of FreeSurfer versions on structural neuroimaging analyses of Parkinson's disease
通过单细胞电感耦合等离子体质谱法快速精确量化淋巴细胞铁含量	Holdship, P.	PDF	N/A	Rapid and precise quantification of lymphocyte iron content by single cell inductively coupled plasma mass spectrometry
约氏疟原虫的特化S型核糖体增强了宿主到媒介的疟疾传播	McGee, J. P.	PDF	N/A	Specialized S-type ribosomes of Plasmodium yoelii enhance host-to-vector malaria transmission
在利什曼原虫（Leishmania major）中，核DNA复制依赖于每个染色体上的一个组成性起始点，并辅以数千次随机起始事件。	Damasceno, J. D.	PDF	N/A	Nuclear DNA replication in Leishmania major relies on a single constitutive origin per chromosome supplemented by thousands of stochastic initiation events
Cochlin的缺失导致肌腱结构和功能的损伤	Adjei-Sowah, E.	PDF	N/A	Loss of Cochlin drives impairments in tendon structure and function
SARS-CoV-2对宿主胆固醇的操控	Doyle, A.	PDF	N/A	Manipulation of Host Cholesterol by SARS-CoV-2
纳米孔数据类型、碱基识别与组装算法比较：单个MinION流式细胞仪的全植物基因组组装及甲基化分析	Martin, S.	PDF	N/A	A Comparison of Nanopore Data Types, Basecalling, and Assembly Algorithms: Whole Plant Genome Assembly and Methylation Analysis from a Single MinION Flow cell
光亲和标记技术助力在天然细胞中转录组范围内鉴定剪接调控小分子-RNA结合事件	Shah, R.	PDF	N/A	Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells
驱动神经退行性溶酶体贮积障碍模型中小胶质细胞表观遗传和转录反应的机制	Balak, C. D.	PDF	N/A	Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model
内嗅皮层中的反复抑制性动态支持模式分离	Zheng, Y.	PDF	N/A	Recurrent Inhibitory Dynamics in the Entorhinal Cortex Support Pattern Separation
7特斯拉下SNR高效的全脑伪连续动脉自旋标记灌注成像	Woods, J. G.	PDF	N/A	SNR-Efficient Whole-Brain Pseudo-Continuous Arterial Spin Labeling Perfusion Imaging at 7 Tesla
转铁蛋白受体介导的血液-脑屏障运输在早期发育中升高，但在成年衰老过程中保持稳定。	Torres, V. O.	PDF	N/A	Transferrin receptor-mediated transport at the blood-brain barrier is elevated in early development but maintained across adult aging
多尺度基于云的神经电生理分析与可视化管道	Geng, J.	PDF	N/A	Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization
在哺乳动物皮层胶质发生和胶质瘤发生过程中，通过Olig1/2调控少突胶质前体细胞与嗅球中间神经元的命运	TIAN, Y.	PDF	N/A	Orchestrating the Acquisition of Oligodendrocyte Precursor Cell versus Olfactory Bulb Interneuron Fates through Olig1/2 during Mammalian Cortical Gliogenesis and Gliomagenesis
解码嗅结节中的中脑边缘多巴胺传递及其通过神经化学感应和化学遗传学对甲基苯丙胺反应的贡献	Bhimani, R. V.	PDF	N/A	Decoding mesolimbic dopamine transmission in the olfactory tubercle and its contribution to methamphetamine responses through neurochemical sensing and chemogenetics
姜黄素通过CDK5/p35信号通路减轻小胶质细胞介导的慢性神经性疼痛	Tong, F.	PDF	N/A	Curcumin attenuates microglia-mediated chronic neuropathic pain through CDK5 /p35 signaling pathway
空间工作记忆期间发作间期的尖波携带有助于或干扰空间表征，并对表现产生相反的影响。	Yi, J. D.	PDF	N/A	Interictal spikes during spatial working memory carry helpful or distracting representations of space and have opposing impacts on performance.
黑质网状部至中缝背核的谷氨酸能投射促进小鼠的社会等级	Fan, Y.	PDF	N/A	The Glutamatergic Projection from the Substantia Nigra Pars Reticulata to the Dorsal Raphe Nucleus Facilitates Social Hierarchy in Mice
受损的蛋白酶体引发线粒体DNA释放，激活小鼠脑中的cGAS-STING信号通路并导致坏死。	Dwamena, A.	PDF	N/A	Impaired proteasome induces mitochondrial DNA release to activate the cGAS-STING signaling pathway and cause necroptosis in mouse brain
基于MRI的人类神经发育新生物型与冲动行为表现相关	Zhou, Z.	PDF	N/A	Novel MRI-based Biotypes of Human Neurodevelopment associated with Impulsivity performance
不同频率的胡须刺激揭示了清醒大鼠感觉系统中功能性磁共振成像信号的非均匀调制	Paasonen, J.	PDF	N/A	Whisker stimulation with different frequencies reveals non-uniform modulation of functional magnetic resonance imaging signal across sensory systems in awake rats
沙漠蝗虫听觉功能的性别差异	Austin, T.	PDF	N/A	Sex differences in auditory function of the desert locust
在少突胶质细胞命运决定期间，procaspase-3的瞬时上调	Kamen, Y.	PDF	N/A	Transient upregulation of procaspase-3 during oligodendrocyte fate decisions
YORU：基于用户定义动物外观的深度学习社交行为检测	YAMANOUCHI, H. M.	PDF	N/A	YORU: social behavior detection based on user-defined animal appearance using deep learning
Nrf2 在成年小鼠大脑中以细胞类型特异性的方式调控体内平衡转录特征和炎症反应。	He, X.	PDF	N/A	Nrf2 controls homeostatic transcriptional signatures and inflammatory responses in a cell-type specific manner in the adult mouse brain
间充质细胞衍生的细胞外囊泡改善了恒河猴工作记忆的年龄相关性缺陷以及脑部MRI和脑脊液中神经退行性变的体内生物标志物。	Mackie, E. C.	PDF	N/A	Mesenchymal Cell-Derived Extracellular Vesicles Ameliorate Age-Related Deficits in Working Memory as well as Brain MRI and CSF in vivo Biomarkers of Neurodegeneration in Rhesus Monkeys.
中脑多巴胺D2R调节与威胁相关事件的显著性	Castell, L.	PDF	N/A	Midbrain dopamine D2R regulates the salience of threat-related events
在自我思考期间，mPFC中认知过程的分解	Levorsen, M.	PDF	N/A	Decomposing Cognitive Processes in the mPFC During Self-Thinking
低频皮层活动反映了依赖于语境的词序列解析	Chen, H.	PDF	N/A	Low-frequency Cortical Activity Reflects Context-dependent Parsing of Word Sequences
小脑中的神经计算向量微积分	Fakharian, M. A.	PDF	N/A	A vector calculus for neural computation in the cerebellum
成人脑膜的整合分层图谱	Degenhard, T.	PDF	N/A	An integrative layer-resolved atlas of the adult human meninges
人类上行觉醒系统皮层下核团编码预期奖励，但不预测后续记忆	Lloyd, B.	PDF	N/A	Subcortical nuclei of the human ascending arousal system encode anticipated reward but do not predict subsequent memory
基于钙的输入时序学习	Kamalabad, S. S.	PDF	N/A	Calcium-based input timing learning
果糖-2,6-二磷酸恢复了运动神经元疾病中TDP-43病理驱动的基因组修复缺陷	Mitra, J.	PDF	N/A	Fructose-2,6-bisphosphate restores TDP-43 pathology-driven genome repair deficiency in motor neuron diseases
果蝇神经元的独特非对称分支优化了时间树突计算	Chou, P.-J.	PDF	N/A	Unique Asymmetric Branching of Drosophila Neurons Optimizes Temporal Dendritic Computation
猕猴外侧膝状体神经元的单细胞转录组分析揭示了新的亚群	Sun, S. H.	PDF	N/A	Single-cell transcriptomic analysis of macaque LGN neurons reveals novel subpopulations
与加速的产后发育长期功能连接组相关的自发脑动力学	Ma, L.	PDF	N/A	Spontaneous Brain Dynamics Associated With Acceleration Of Longterm Functional Connectome In Postnatal Development
深度神经网络解释了听觉皮层的尖峰活动	Ahmed, B.	PDF	N/A	Deep Neural Networks Explain Spiking Activity in Auditory Cortex
肌萎缩侧索硬化症（ALS）大脑和脊髓中神经免疫区室的单细胞转录组图谱	Tuddenham, J.	PDF	N/A	Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord
帕金森病患者在在线和离线运动序列学习中受损和增强	Van Roy, A.	PDF	N/A	Impaired online and enhanced offline motor sequence learning in individuals with Parkinson's disease
在做出感知决策以在不同行动之间进行选择时，人类会预见运动控制需求的结果。	Leroy, E.	PDF	N/A	Humans anticipate the consequences of motor control demands when making perceptual decisions between actions
降低蓝斑核去甲肾上腺素能信号传导至脊髓星形胶质细胞亚群是应激诱发疼痛易化所必需的。	Kawanabe-Kobayashi, R.	PDF	N/A	Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation
价值对与任务无关的听觉失配负波无影响	Hutchinson, B. T.	PDF	N/A	No Effect of Value on the Task Irrelevant Auditory Mismatch Negativity
病理性微电路在患者海马切片中启动癫痫样事件	Elliott, M.	PDF	N/A	Pathological microcircuits initiate epileptiform events in patient hippocampal slices
工作记忆中感觉和运动内容的动态优先级排序	Echeverria-Altuna, I.	PDF	N/A	Dynamic prioritisation of sensory and motor contents in working memory
星形胶质细胞连接蛋白43的磷酸化作用在轻度创伤性脑损伤后对癫痫易感性的影响	Munoz-Ballester, C.	PDF	N/A	Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild Traumatic Brain Injury
恢复精神分裂症中的突触平衡：基于丘脑-皮层电导模型的见解。	Berndt, L. C. S.	PDF	N/A	Restoring Synaptic Balance in Schizophrenia: Insights from a thalamo-cortical conductance-based model.
大鼠体感皮层血液流动动力学的建模	Battini, S.	PDF	N/A	Modeling of blood flow dynamics in the rat somatosensory cortex
空间转录组学分析鉴定出一种表达SERPINA3的星形胶质细胞状态，与人类神经炎斑微环境相关	Karaahmet, B.	PDF	N/A	Spatial Transcriptomic Analysis Identifies a SERPINA3-Expressing Astrocytic State Associated with the Human Neuritic Plaque Microenvironment
硫脂缺乏引起的星形胶质细胞增生和髓鞘脂质稳态失调与Trem2介导的微胶质细胞激活无关。	Mittra, N.	PDF	N/A	Sulfatide deficiency-induced astrogliosis and myelin lipid dyshomeostasis are independent of Trem2-mediated microglial activation
miR-29a调控对成年大脑记忆稳定性的双向影响	Viglione, A.	PDF	N/A	Bidirectional Impact of miR-29a modulation on Memory Stability in the Adult Brain
一种基于PET的功能激活和分子连接识别的统一方法，借助功能PET工具箱实现	Hahn, A.	PDF	N/A	A Unified Approach for Identifying PET-based Neuronal Activation and Molecular Connectivity with the functional PET toolbox
由特定亚型TrkB-T1序列建立的相互作用调控中风中的炎症反应和神经毒性	Ugalde-Trivino, L.	PDF	N/A	Interactions established by isoform-specific TrkB-T1 sequences govern inflammatory response and neurotoxicity in stroke
使用潜在状态逆强化学习建模复杂动物行为	Jha, A.	PDF	N/A	Modeling Complex Animal Behavior with Latent State Inverse Reinforcement Learning
年长即有序：皮层自发活动的熵减少标志着健康衰老	Chang, D.	PDF	N/A	Older is Order: Entropy reduction in cortical spontaneous activity marks healthy aging
脑功能网络连接插值法表征了神经精神连续谱与异质性	Li, X.	PDF	N/A	Brain functional network connectivity interpolation characterizes neuropsychiatric continuum and heterogeneity
大规模脑干记录中尖峰分类器的比较分析	De Preter, C. C.	PDF	N/A	Comparative analysis of spike-sorters in large-scale brainstem recordings
多模态探究成年阅读障碍背后的神经认知缺陷	Cara, C.	PDF	N/A	Multimodal investigation of the neurocognitive deficits underlying dyslexia in adulthood
性相关基因表达在循环雌性大鼠后内侧杏仁核中的表现以及催乳素对雌性大鼠交配行为的影响	Buhler, L.	PDF	N/A	SEX-RELATED GENE EXPRESSION IN THE POSTERODORSAL MEDIAL AMYGDALA OF CYCLING FEMALE RATS ALONG WITH PROLACTIN MODULATION OF LORDOSIS BEHAVIOR
特征相似性：一种敏感的方法，用于捕捉脑区和网络的功能相互作用，以支持灵活的行为	Wang, X.	PDF	N/A	Feature similarity: a sensitive method to capture the functional interaction of brain regions and networks to support flexible behavior
核糖体丰度，而非旁系同源基因组成，对生殖系发育至关重要	Grobicki, K. Z. A.	PDF	N/A	Ribosome abundance, not paralogue composition, is essential for germline development
钙信号传导在小鼠胚胎的前部模式形成中是必需的。	Stower, M.	PDF	N/A	Calcium signalling is required for anterior patterning in the mouse embryo
在终末期红细胞生成过程中，血红蛋白的高效生产依赖于TENT5C多聚腺苷酸聚合酶与LARP4/5的协同作用。	Mazur, M.	PDF	N/A	Efficient globin production during terminal erythropoiesis depends on the synergistic action of TENT5C poly(A) polymerase and LARP4/5
PP2A磷酸酶在Hippo信号调控中具有双重作用	Sekar, A.	PDF	N/A	A Dual Role for the PP2A Phosphatase in Hippo Signalling Regulation
Hox13通过与Fgf10和Tbx4相互作用调控蝾螈后肢芽外突的新功能	Tozawa, S.	PDF	N/A	Novel function of Hox13 in regulating outgrowth of the newt hindlimb bud through interaction with Fgf10 and Tbx4
及时的神经发生能够促进神经元分层过程中核包装顺序的增加	Ferme, L. C.	PDF	N/A	Timely neurogenesis enables increased nuclear packing order during neuronal lamination
Sox9和Nfi转录因子调控多巴胺前体细胞中神经发生和室管膜成熟的时机	Lahti, L.	PDF	N/A	Sox9 and Nfi transcription factors regulate the timing of neurogenesis and ependymal maturation in dopamine progenitors
Koolen-de Vries综合征的致病基因KANSL1对于运动纤毛的生成是必需的。	Schmidt, J. D.	PDF	N/A	Koolen-de Vries Syndrome causal gene KANSL1 is required for motile ciliogenesis
利用机器智能进行回溯性运动分析，预测情绪障碍的潜在风险	Jung, W.	PDF	N/A	Back-to-the-future motion analysis using machine intelligence predicts the potential risk of mood disorders
黑猩猩手势序列中下一个元素的可预测性	Mielke, A.	PDF	N/A	Predictability of next elements in chimpanzee gesture sequences
刺激的不确定性和相对奖励率决定了感知决策中的适应性反应	de la Cuesta-Ferrer, L.	PDF	N/A	Stimulus uncertainty and relative reward rates determine adaptive responding in perceptual decision-making
在乳腺癌诱导骨痛的小鼠模型中，数字通风笼（Digital Ventilated Cages）内的轮跑活动受损，而家庭笼内的活动未受影响。	Hopkins, C.	PDF	N/A	Wheel running, but not home cage activity in Digital Ventilated Cages(R) is impaired in a mouse model of breast cancer-induced bone pain
慢性口服尼古丁对年轻成年早老素-1/2双敲除痴呆模型小鼠的嗅觉功能障碍无改善作用	Si, Y.	PDF	N/A	Lack of Ameliorative Effect of Chronic Oral Nicotine on Olfactory Dysfunction in Young Adult Presenilin-1/2 Double Knockout Mice of a Dementia Model
增强牛磺酸摄取的牛磺酸转运蛋白的结构基础缓解细胞衰老	Zhang, H.	PDF	N/A	Structural basis of augment taurine uptake by taurine transporter alleviating cellular senescence
注意你的光谱：验证同量异位组蛋白肽段形式鉴定时需要注意的要点	Hijazi, H.	PDF	N/A	Mind Your Spectra: Points to be Aware of when Validating the Identification of Isobaric Histone Peptidoforms
使用表达植酸酶的酿酒酵母减少高粱面团中的抗营养因子植酸	Kale, T.	PDF	N/A	Reducing phytate, an antinutritional factor, in sorghum dough using phytase-expressing Saccharomyces cerevisiae
在长达五亿年的进化过程中，顺式调控密码的保守性	Ogawa, Y.	PDF	N/A	Conservation of cis-regulatory codes over half a billion years of evolution
驯化对犬科动物中新氨基酸改变突变的选择效应的进化影响	G. Amorim, C. E.	PDF	N/A	Evolutionary consequences of domestication on the selective effects of new amino acid changing mutations in canids
一个多组织发育基因表达图谱，旨在理解绵羊表型的生物学基础	Zhao, B.	PDF	N/A	A multi-tissue developmental gene expression atlas towards understanding the biological basis of phenotypes in sheep
人类基因组的调控可塑性	Srivastava, J.	PDF	N/A	Regulatory plasticity of the human genome
# BioRxiv 2024-11-13 Papers

标题	作者	PDF链接	代码仓库	Title
药物抗性感染的机械时空模型	Lee, T. E.	PDF	N/A	A mechanistic spatiotemporal model for drug resistant infections
普通豆（Phaseolus vulgaris L.）对土壤干燥的全株蒸腾响应：水通道蛋白与转录因子	Cordoba-Novoa, H. A.	PDF	N/A	Whole Plant Transpiration Responses of Common Bean (Phaseolus vulgaris L.) to Drying Soil: Water Channels and Transcription Factors
为什么作物多模型研究中存在如此大的差异性？	Wallach, D.	PDF	N/A	Why is there so much variability in crop multi-model studies?
克隆进化介导了KMT2A重排白血病中的Menin抑制剂耐药性。	Mahdavi, L.	PDF	N/A	Clonal evolution mediates Menin-inhibitor resistance in KMT2A-rearranged leukemias.
心脏转录增强子在再生过程中被重新利用，以激活一种抗增殖程序	Rao, A.	PDF	N/A	A Cardiac Transcriptional Enhancer is Repurposed During Regeneration to Activate an Anti-proliferative Program
SNP分配用于估计遗传力（SAFE-h2）：一种探索表型基因组起源的工具，用于使用仅加性等位基因效应或加性和非加性等位基因效应估计SNP遗传力	Darbani, B.	PDF	N/A	SNP Allocation For Estimating Heritability (SAFE-h2): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects
炎症诱导的Claudin-2上调通过增强紧密连接调控的胰管运输来限制胰腺炎的进展。	Kesaraju, S.	PDF	N/A	Inflammation-Induced Claudin-2 Upregulation Limits Pancreatitis Progression by Enhancing Tight Junction-Controlled Pancreatic Ductal Transport
展望未来：利用双翅目-沃尔巴克氏体系统的转录组元分析来预测虫媒病毒策略的可持续性	Mejias, S.	PDF	N/A	A look into the the future: using a transcriptomic meta-analysis of Diptera-Wolbachia systems to project sustainability of arboviral strategies
腭部结构对中面部前后向生长的贡献	Welsh, I. C.	PDF	N/A	Palatal segment contributions to midfacial anterior-posterior growth
TreePPL：一种适用于系统发育学的通用概率编程语言	Senderov, V. E.	PDF	N/A	TreePPL: A Universal Probabilistic Programming Language for Phylogenetics
组合CRISPR筛选揭示FYN和KDM4为治疗三阴性乳腺癌的协同药物组合靶点	Kim, T.	PDF	N/A	Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer
通过基于结构稳定性的筛选，利用易于获取的人工同源序列实现蛋白质结构的高精度预测	Tang, J.	PDF	N/A	Effective High-Accuracy Prediction of Protein Structures from Easily Obtainable Artificial Homologous Sequences by Structure-Stability-Based Selection
伊朗-安纳托利亚和高加索生物多样性热点地区的进化动力学：石竹科（Caryophyllaceae）中石竹属（Gypsophila）的进化辐射及其驱动因素	Madhani, H.	PDF	N/A	Evolutionary dynamics in Irano-Anatolian and Caucasus biodiversity hotspots: Evolutionary radiation and its drivers in Gypsophila (Caryophyllaceae)
选择解释而非性能：基于机器学习的从脑连接预测人类智力的洞察	Thiele, J. A.	PDF	N/A	Choosing explanation over performance: Insights from machine learning-based prediction of human intelligence from brain connectivity
将梯度提升树应用于QTL定位，并结合Shapley加性解释	Ishibashi, T.	PDF	N/A	Applying gradient tree boosting to QTL mapping with Shapley additive explanations
学习到的反应动力学反映了刺激的时序，并在小鼠初级视觉皮层（V1）的浅层编码了时间预期的违反。	Knudstrup, S. G.	PDF	N/A	Learned response dynamics reflect stimulus timing and encode temporal expectation violations in superficial layers of mouse V1
BiaPy：生物图像上的可访问深度学习	Franco-Barranco, D.	PDF	N/A	BiaPy: Accessible deep learning on bioimages
致关节炎小鼠中致病性Th17细胞的TCR谱系向Treg样谱系偏移	Llamas-Covarrubias, M. A.	PDF	N/A	The TCRs of pathogenic Th17 cells in arthritogenic mice are shifted toward a Treg-like repertoire
精细尺度的海洋学过程塑造了加拉帕戈斯群岛的海洋生物多样性模式。	Holman, L. E.	PDF	N/A	Fine-scale oceanographic processes shape marine biodiversity patterns in the Galapagos Islands
Celldetective：一款利用人工智能增强的图像分析工具，用于揭示动态细胞相互作用	Torro, R.	PDF	N/A	Celldetective: an AI-enhanced image analysis tool for unraveling dynamic cell interactions
自然行为的视觉运动协调的低维表示	Keshava, A.	PDF	N/A	Low-Dimensional Representations of Visuomotor Coordination for Natural Behavior
凝聚素IDC、H4K20me1及核周锚定维持秀丽隐杆线虫X染色体的抑制状态	Trombley, J.	PDF	N/A	Condensin IDC, H4K20me1, and perinuclear tethering maintain X chromosome repression in C. elegans
果蝇的背侧扇形体是一个神经化学成分异质的睡眠调节中心。	Jones, J. D.	PDF	N/A	The dorsal fan-shaped body is a neurochemically heterogeneous sleep-regulating center in Drosophila
化学遗传学刺激膈肌运动输出和膈肌活动	Benevides, E. S.	PDF	N/A	Chemogenetic stimulation of phrenic motor output and diaphragm activity
5-HT1A受体在斑马鱼对潜在威胁的反应及社交性中的作用	de Sousa, L. V. X. B.	PDF	N/A	Roles of the 5-HT1A receptor in zebrafish responses to potential threat and in sociality
利用贝叶斯参数估计与条件变分自编码器识别肌肉中的机制与治疗靶点	Tune, T. C.	PDF	N/A	Identifying mechanisms and therapeutic targets in muscle using Bayesian parameter estimation with conditional variational autoencoders
在口头叙事理解中，大脑状态动态的三部分组织	Liu, L.	PDF	N/A	Tripartite organization of brain state dynamics underlying spoken narrative comprehension
基于脑电图的连续语音包络重构的语音接收阈值估计	Borges, H. B.	PDF	N/A	Speech-reception-threshold estimation via EEG-based continuous speech envelope reconstruction
空转：缺乏线粒体DNA的线粒体表现出差异化的运动性和连接性	Chustecki, J. M.	PDF	N/A	Running on empty: Mitochondria without mtDNA exhibit differential motility and connectivity
微生物种群几乎从未以逻辑斯蒂方式增长，也从未以亚线性方式增长。	Camacho-Mateu, J.	PDF	N/A	Microbial populations hardly ever grow logistically and never sublinearly
限时进食对饮食诱导的肥胖大鼠提供了有限的微胶质免疫代谢改善	Jiao, H.	PDF	N/A	Time-restricted feeding provides limited microglial immunometabolic improvements in diet-induced obese rats
情感背景影响有蹄类动物的声纹特征	Osiecka, A. N.	PDF	N/A	Emotional contexts influence vocal individuality in ungulates
一个用于筛选巨噬细胞外消化脂蛋白聚集体调节剂的高内涵显微镜药物筛选平台	Ma, C.-I. J.	PDF	N/A	A high-content microscopy drug screening platform for regulators of the extracellular digestion of lipoprotein aggregates by macrophages
基于模拟的TMEM16家族调查显示，强健的脂质翻转需要一个开放的沟槽	Stephens, C. A.	PDF	N/A	Simulation-based survey of TMEM16 family reveals that robust lipid scrambling requires an open groove
利用二维和三维图像分析工具对成年小鼠脑样本中微胶质细胞形态复杂性进行的比较研究	Murray, C. J.	PDF	N/A	A comparison of microglial morphological complexity in adult mouse brain samples using 2-dimensional and 3-dimensional image analysis tools
BAK驱动的凋亡孔形成的脂质特征	Uren, R. T.	PDF	N/A	A lipid signature of BAK-driven apoptotic pore formation
针对铜绿假单胞菌III型分泌系统PcrV组分的抗人单克隆抗体通过不同的机制发挥中和作用	Desveaux, J.-M.	PDF	N/A	Neutralizing human monoclonal antibodies that target the PcrV component of the Type III Secretion System of Pseudomonas aeruginosa act through distinct mechanisms
冷冻区动力学的数学建模：向在冷冻疗法中使用热成像仪迈进	Ivakhnenko, O. V.	PDF	N/A	Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy
RSV基因组中的G-四链体：潜在的抗病毒靶点。	Bose, D.	PDF	N/A	G-quadruplexes in the RSV genome: potential anti-viral targets.
背内侧纹状体中的神经炎症通过破坏稳态星形胶质细胞功能，导致目标导向行为控制过度。	Abiero, A. R.	PDF	N/A	Neuroinflammation in the dorsomedial striatum causes excessive goal-directed action control by disrupting homeostatic astrocyte function
斑马鱼中个体保守神经元微外显子及其主调控因子的表型影响	Lopez-Blanch, L.	PDF	N/A	Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish
FoldMark：通过水印保护蛋白质生成模型	ZHANG, Z.	PDF	N/A	FoldMark: Protecting Protein Generative Models with Watermarking
评估人类祖先颅牙特征的系统发育信息含量和冗余性	Raskin, L. Y.	PDF	N/A	Assessing phylogenetic information content and redundancy in hominin craniodental traits
Aramchol减轻了小鼠胆道纤维化模型中的纤维化，并阻断了TGFβ诱导的胆管细胞中的纤维炎症介质。	Aseem, S. O.	PDF	N/A	Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes
人类行为中逐次试验学习后继表征	Kahn, A. E.	PDF	N/A	Trial-by-trial learning of successor representations in human behavior
基于捕获离子迁移支持的MALDI MS/MS成像的空间蛋白质组学：多重和空间肽鉴定的初步观察	Li, M. J.	PDF	N/A	Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification
夜行土豚（Orycteropus afer，管齿目）的眼部特征与视网膜光感受器	Peichl, L.	PDF	N/A	Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata)
跨平台DNA基序发现与基准测试：探索研究不足的人类转录因子结合特异性	Vorontsov, I. E.	PDF	N/A	Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors
ER Ca2+水平通过调节STIM1和L型Ca2+通道活性来控制神经调质的分泌。	Hoogstraaten, R. I.	PDF	N/A	ER Ca2+-levels control neuromodulator secretion by regulating STIM1 and L-type Ca2+-channel activity
溶酶体自主调节髓系细胞状态和免疫反应	Tejwani, L.	PDF	N/A	Lysosomes cell autonomously regulate myeloid cell states and immune responses
空间限制诱导表皮角质形成细胞的往复迁移，并形成三相上皮	Nohara, T.	PDF	N/A	Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia
在小鼠下呼吸道中进行靶向预处理和细胞移植	Kohn, A.	PDF	N/A	Targeted pre-conditioning and cell transplantation in the murine lower respiratory tract
TMEM55B的丢失通过失调的脂噬作用和线粒体功能调节脂质代谢	Qin, Y.	PDF	N/A	Loss of TMEM55B modulates lipid metabolism through dysregulated lipophagy and mitochondrial function
CEP152与PLK4的结合刺激了激酶活性，从而促进中心粒的组装。	Hoffmann, I.	PDF	N/A	Binding of CEP152 to PLK4 stimulates kinase activity to promote centriole assembly
信号素4A维持造血干细胞池的功能多样性	Toghani, D.	PDF	N/A	Semaphorin 4A maintains functional diversity of the hematopoietic stem cell pool
βTrCP1的过度表达可诱导顺铂诱导的衰老细胞发生细胞死亡。	Belmonte-Fernandez, A.	PDF	N/A	Overexpression of betaTrCP1 elicits cell death in cisplatin-induced senescent cells
一种与Rett综合征相关的KCNC1变异体破坏了Kv3.1通道从内质网到高尔基体的运输	Maureira, D.	PDF	N/A	A KCNC1 Variant Linked to Rett Syndrome Disrupts ER to Golgi Trafficking of Kv3.1 Channel
NG497对脂肪甘油三酯脂肪酶的急性抑制作用扰乱了人胰岛中胰岛素和胰高血糖素的分泌	Kim, L.	PDF	N/A	Acute Inhibition of Adipose Triglyceride Lipase by NG497 Dysregulates Insulin and Glucagon Secretion from Human Islets
从在线模式回归线下生物化学顶点实验室：从新冠疫情在线教学模式中汲取的经验教训，以提升基于课程的本科生科研体验	Rascon, A. A.	PDF	N/A	Pivoting Back to the In-Person Capstone Biochemistry Lab: Lessons Learned from the COVID-19 Online Modality to Improve the Course-based Undergraduate Research Experience
评估生成式人工智能在环境研究科学传播中的质量	Worden, D.	PDF	N/A	Assessing the quality of generative artificial intelligence for science communication in environmental research
在捕食飞行过程中，蜻蜓目标探测神经元的无线记录	Lin, H.-T.	PDF	N/A	Wireless recordings from dragonfly target detecting neurons during prey interception flight
慢性可变轻度应激以性别依赖的方式改变了终纹床核前背侧核的转录组和信号传导特性	Degroat, T. J.	PDF	N/A	Chronic variable mild stress alters the transcriptome and signaling properties of the anterodorsal bed nuceleus of the stria terminalis in a sex-dependent manner
利用蛋白质组学分析和配体结合实验探索神经退行性疾病的新型生物标志物	Kenzelmann, A.	PDF	N/A	Exploration of novel biomarkers for neurodegenerative diseases using proteomic analysis and ligand-binding assays
非临床和临床环境中的优柔寡断与近期加权证据整合	del Rio, M.	PDF	N/A	Indecision and recency-weighted evidence integration in non-clinical and clinical settings
血清代谢组学分析显示，轻度认知障碍患者在脂质代谢方面存在性别差异。	Diaz Escarcega, R.	PDF	N/A	Serum metabolome profiling in patients with mild cognitive impairment reveals sex differences in lipid metabolism
用于检测盐杆菌慢性感染病毒的优化噬菌斑检测法	Navok, S.	PDF	N/A	Optimized Plaque Assay for Detecting Chronically Infecting Viruses of Haloarchaea
坏死性凋亡向凋亡信号轴是炎症性肠病的基础	Pang, J.	PDF	N/A	A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
异染色质表观突变通过引发线粒体功能障碍，从而赋予抗真菌抵抗力。	Fellas, A.	PDF	N/A	Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance
三种全球大肠杆菌转录调节因子的适应性景观	Antunes Westmann, C.	PDF	N/A	The adaptive landscapes of three global Escherichia coli transcriptional regulators
温室马铃薯蚜虫（Aulacorthum solani）的初步基因组序列	Torres, J.	PDF	N/A	Draft genome sequence of the glasshouse-potato aphid Aulacorthum solani
invertiaDB：一个跨物种基因组倒位重复数据库	Provatas, K.	PDF	N/A	invertiaDB: A Database of Inverted Repeats Across Organismal Genomes
多细胞整体控制器代谢负担效应的计算机模拟分析	Campanile, G.	PDF	N/A	In silico analysis of metabolic burden effects on a multicellular integral controller
多模态状态依赖性连接分析：脑干和基底前脑中的觉醒与自主神经中枢	Pourmotabbed, H.	PDF	N/A	Multimodal state-dependent connectivity analysis of arousal and autonomic centers in the brainstem and basal forebrain
Srs2/PARI DNA解旋酶介导了酵母和人细胞中染色质桥响应的细胞分离抑制	Dam, M.	PDF	N/A	Srs2/PARI DNA helicase mediates abscission inhibition in response to chromatin bridges in yeast and human cells
城市共居景观：在ECOLOPES框架下探索欧洲共居土地景观的多样性。	Oneto, G.	PDF	N/A	Urban Cohabscapes: exploring European Co-Habitative landScapes diversity, in the ECOLOPES framework.
通过mRNA实现人类皮肤再生	Li, L.	PDF	N/A	Human skin rejuvenation via mRNA
结合细胞学和蛋白质组学的方法表明，海绵Halichondria panicea对本地和外来弧菌的处理存在差异。	Marulanda-Gomez, A. M.	PDF	N/A	Combined cellular and proteomics approach suggest differential processing of native and foreign vibrios in the sponge Halichondria panicea
不同SARS-CoV-2病毒变种（武汉株、Delta株、Omicron株）在模型动物器官中积累的比较特征	Chernov, A.	PDF	N/A	COMPARATIVE CHARACTERISTICS OF THE ACCUMULATION OF DIFFERENT VARIANTS OF THE SARS-COV-2 VIRUS (WUHAN, DELTA, OMICRON) IN THE ORGANS OF MODEL ANIMALS
一种伴侣蛋白复合物调控疟原虫细胞器的蛋白质稳态	Tissawak, A.	PDF	N/A	A Chaperonin Complex Regulates Organelle Proteostasis in Malaria Parasites
植物病原菌红球菌中发现利迪霉素A生物合成基因簇，指导结构修正和分子靶点鉴定	Ford, J. J.	PDF	N/A	Discovery of lydiamycin A biosynthetic gene cluster in the plant pathogen Rhodococcus fascians guides structural revision and identification of molecular target
SARS-CoV-2 EndoU核糖核酸酶调控RNA重组并影响病毒适应性。	Zhou, Y.	PDF	N/A	SARS-CoV-2 EndoU-ribonuclease regulates RNA recombination and impacts viral fitness.
大肠杆菌K12中tRNA修饰缺陷的协同效应。	Bacusmo, J. o. M.	PDF	N/A	Synergistic effects of tRNA modification defects in Escherichia coli K12.
同时考虑选择和微生物生成计数，为理解全生物体的进化和生态动态提供了独特的见解。	Pearman, W. S.	PDF	N/A	Joint consideration of selection and microbial generation count provides unique insights into evolutionary and ecological dynamics of holobionts
霍乱弧菌的谱系和泛基因组多样性在孟加拉国一年内呈现出地理上的变化。	Qin, C.	PDF	N/A	Vibrio cholerae lineage and pangenome diversity varies geographically across Bangladesh over one year
最近SARS-CoV-2变种被pemivibart谱系中基因和结构相关的单克隆抗体中和	Powers, C.	PDF	N/A	Neutralization of recent SARS-CoV-2 variants by genetically and structurally related mAbs of the pemivibart lineage
基于造血干细胞的抗HIV-1基因疗法，配备安全终止开关，以防御和攻击HIV-1感染	Guo, Q.	PDF	N/A	Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection
探究intimin/invasin在嗜水气单胞菌（Aeromonas hydrophila）对露比鱼（Labeo rohita）致病性中的潜在作用：宿主-微生物相互作用研究	Bhattacharyya, A.	PDF	N/A	Investigating the potential role of intimin/invasin in Aeromonas hydrophila virulence in Labeo rohita: a host-microbe interaction study
绘制按蚊雌蚊中疟原虫的转变与相互作用	Yan, Y.	PDF	N/A	Mapping Plasmodium transitions and interactions in the Anopheles female
元蛋白质组学揭示了仓鼠感染SARS-CoV-2后肠道微生物组的年龄特异性改变	Creskey, M.	PDF	N/A	Metaproteomics reveals age-specific alterations of gut microbiome in hamsters with SARS-CoV-2 infection
人类ClpXP的冷冻电镜结构揭示了其组装和蛋白水解激活的机制	Chen, W.	PDF	N/A	Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation
寄生线虫单细胞核分离与RNA测序的优化	Buddenborg, S. K.	PDF	N/A	Optimisation of single-nuclei isolation and RNA sequencing of parasitic nematodes
整合石莼功能基因组学：基因编辑与新型筛选系统	Blomme, J.	PDF	N/A	Consolidating Ulva functional genomics: Gene editing and new selection systems
小分子抑制剂联合治疗能有效抑制弥漫性大B细胞淋巴瘤中的B细胞信号传导。	Witmond, M.	PDF	N/A	Small molecule inhibitor combination treatment effectively represses global B-cell signaling in diffuse large B-cell lymphoma
SARS-CoV-2 XEC变体的免疫逃逸、细胞融合及刺突蛋白稳定性：N端结构域糖基化突变的作用	Li, P.	PDF	N/A	Immune Evasion, Cell-Cell Fusion, and Spike Stability of the SARS-CoV-2 XEC Variant: Role of Glycosylation Mutations at the N-terminal Domain
细菌乙酰转移酶PatZ的催化及变构机制的结构基础	Park, J. B.	PDF	N/A	Structural basis of the catalytic and allosteric mechanism of bacterial acetyltransferase PatZ
病毒感染期间ATP分配的动态代谢建模	Lu, A.	PDF	N/A	Dynamic metabolic modeling of ATP allocation during viral infection
端粒转座子广泛存在于线性细菌基因组中。	Hsieh, S.-C.	PDF	N/A	Telomeric transposons are pervasive in linear bacterial genomes
G蛋白偶联受体17通过Gi/o依赖机制抑制肠内分泌细胞中胰高血糖素样肽-1的分泌	Conley, J. M.	PDF	N/A	G protein-coupled receptor 17 inhibits glucagon-like peptide-1 secretion via a Gi/o-dependent mechanism in enteroendocrine cells
有丝分裂中的CIP2A-TOPBP1轴促进MiDAS与MMEJ之间的有丝分裂途径选择。	Martin, P. R.	PDF	N/A	The mitotic CIP2A-TOPBP1 axis facilitates mitotic pathway choice between MiDAS and MMEJ
由细菌微区室封装肽驱动的生物分子凝聚的蓝图	Trettel, D.	PDF	N/A	A blueprint for biomolecular condensation driven by bacterial microcompartment encapsulation peptides
在不确定性下的遗传电路风险规避优化	Kobiela, M.	PDF	N/A	Risk-averse optimization of genetic circuits under uncertainty
# BioRxiv 2024-11-12 Papers

标题	作者	PDF链接	代码仓库	Title
泛素介导的人类26S蛋白酶体在底物降解过程中的自调节隐藏动力学	Wu, Z.	PDF	N/A	Hidden dynamics of ubiquitin-mediated autoregulation of human 26S proteasome during substrate degradation
多重连接组轨迹使得多种连接模式能够并行实现。	Mostame, P.	PDF	N/A	A multiplex of connectome trajectories enables several connectivity patterns in parallel
增强突变热点预测：原子波动的作用	Martis, E. A. F.	PDF	N/A	Enhancing Mutational Hotspot Predictions: The Role of Atomic Fluctuations
肌动蛋白失调引发神经内分泌可塑性和免疫逃逸：小细胞肺癌的一个脆弱性	Seo, Y.	PDF	N/A	Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer
增强轴向光学镊子的应用力和作用范围	Milstein, J. N.	PDF	N/A	Enhancing the Applied Force and Range of Axial Optical Tweezers
撤销：钢琴演奏中认知与情感相互影响的神经生理学	Higuchi, M. K. K.	PDF	N/A	WITHDRAWN: Neurophysiology of Reciprocal Influence of Cognition and Emotion in Pianistic Performances
阿尔茨海默病中性别依赖性脆弱性的原因：后扣带皮层中受损的Parvalbumin中间神经元	Terstege, D. J.	PDF	N/A	Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer's disease
NOTCH1的表达状态转变伴随着人类早期视网膜祖细胞中的染色质重塑	Watabe, Y.	PDF	N/A	Expression status transition of NOTCH1 accompanies chromatin remodeling in human early retinal progenitor cells
探究数学学习困难儿童的前顶叶网络及激活情况：不同缺陷特征的案例研究	Wang, F.	PDF	N/A	Investigating Frontoparietal Networks and Activation in Children with Mathematics Learning Difficulties: Cases with Different Deficit Profiles
scEGOT：基于熵高斯混合最优传输的单细胞轨迹推断框架	Yachimura, T.	PDF	N/A	scEGOT: Single-cell trajectory inference framework based on entropic Gaussian mixture optimal transport
物种特性和群落结构可以推动生态系统中大规模的空间效应传播。	Garcia-Callejas, D.	PDF	N/A	Species traits and community structure can drive large-scale spatial propagation of effects in ecosystems
基于模型的突触可塑性规则推断	Mehta, Y.	PDF	N/A	Model Based Inference of Synaptic Plasticity Rules
室管膜下区神经胶质生成调节脑缺血后胶质瘢痕处的细胞外基质	Ardaya, M.	PDF	N/A	Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia
靶向缺氧人乳腺癌干细胞的分子货物胞内递送	Makela, A. V.	PDF	N/A	Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells
将残基级蛋白质语言模型嵌入与最优传输相结合	NaderiAlizadeh, N.	PDF	N/A	Aggregating Residue-Level Protein Language Model Embeddings with Optimal Transport
驯化的转座子蛋白L1TD1与其祖先L1 ORF1p相互作用，促进LINE-1逆转录转座	Kavaklioglu, G.	PDF	N/A	The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition
基于相关自然统计的高效编码解释的重量错觉	Bays, P.	PDF	N/A	Weight illusions explained by efficient coding based on correlated natural statistics
受损的26S蛋白酶体导致小鼠学习和记忆缺陷，并诱导由NF-κB介导的神经炎症	Huber, C.	PDF	N/A	Impaired 26S proteasome causes learning and memory deficiency and induces neuroinflammation mediated by NF-κB in mice
棕色藻类作为沿海生态系统关键组成部分的进化基因组学研究	Denoeud, F.	PDF	N/A	Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
机械负荷揭示了在小鼠心脏代谢疾病中，心肌细胞固有的刚度对舒张功能障碍的贡献。	Janssens, J. V.	PDF	N/A	Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease
皮质丘脑模型在睡眠神经生理学中的应用及其在移动脑电图中的应用	Morshedzadeh, T.	PDF	N/A	Corticothalamic modelling of sleep neurophysiology with applications to mobile EEG
单细胞RNA测序揭示了不同关系间的转录同步性	Brusman, L. E.	PDF	N/A	Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships
一种涉及巨型可移动元件的古老倒位多态性在入侵性真菌病原体中	Hartmann, F. E.	PDF	N/A	An old inversion polymorphism involving giant mobile elements in an invasive fungal pathogen
在喜马拉雅山西部，尺蛾科蛾类群落的特征分布并不随海拔梯度变化。	Dey, P.	PDF	N/A	Trait distribution in Geometrid moth assemblages does not vary along a western Himalayan elevational gradient
一种涉及多个P450基因的基因组重复有助于登革热蚊子埃及伊蚊的杀虫剂抗性。	Bacot, T.	PDF	N/A	A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
单细胞RNA测序（scRNA-seq）和单细胞ATAC测序（scATAC-seq）揭示了支持细胞通过阶段特异性通信在非阻塞性无精症中调节精子发生障碍	Wang, S.	PDF	N/A	ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia
在生物物理上真实的兴奋-抑制尖峰网络中进行高效编码	Koren, V.	PDF	N/A	Efficient coding in biophysically realistic excitatory-inhibitory spiking networks
多价Afadin相互作用促进IDR介导的凝聚体形成和上皮细胞的连接分离	Kuno, S.	PDF	N/A	Multivalent Afadin Interaction Promotes IDR-Mediated Condensate Formation and Junctional Separation of Epithelial Cells
脑膜调节性T细胞衍生的脑啡肽调控痛觉	Midavaine, E.	PDF	N/A	Meningeal Regulatory T cell-derived enkephalin gates nociception
非巢友歧视在蚂蚁中起到排除社会性寄生同种个体的作用	Nakamura, T. P.	PDF	N/A	Discrimination against non-nestmates functions to exclude socially parasitic conspecifics in an ant
白细胞介素-1通过诱导肌动蛋白束的形成，阻止了SARS-CoV-2诱导的膜融合，从而限制了病毒的传播。	Zheng, X.	PDF	N/A	Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles
fmo-4通过ER到线粒体的钙调节在秀丽隐杆线虫中促进长寿和应激抗性	Tuckowski, A. M.	PDF	N/A	fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans
热带珊瑚礁鱼类的比较宏基因组学研究表明，尽管宿主和饮食各异，但其肠道核心功能高度保守，同时存在与饮食相关的功能基因富集现象。	Wu, D. G.	PDF	N/A	Comparative metagenomics of tropical reef fishes show conserved core gut functions across hosts and diets with diet-related functional gene enrichments
毒力进化：跳出宿主的思维框架	Silva, L. M.	PDF	N/A	Virulence evolution: thinking outside of the host
胰腺癌细胞通过隧道纳米管交换核糖体	Martinkova, S.	PDF	N/A	Pancreatic cancer cells exchange ribosomes through tunneling nanotubes
在裂顎目（sclerosomatid Opiliones）中，婚配礼物的减少与行为性冲突的增加相吻合。	Brown, T. A.	PDF	N/A	The reduction of nuptial gifts in sclerosomatid Opiliones coincides with increased behavioural sexual conflict
细胞信号：多模态与情境化机器学习基础在治疗学中的应用	Velez-Arce, A.	PDF	N/A	Signals in the Cells: Multimodal and Contextualized Machine Learning Foundations for Therapeutics
系统建模揭示了ME/CFS和长期新冠肺炎中共同的代谢失调及新型治疗方法	Li, G.-H.	PDF	N/A	Systems Modeling Reveals Shared Metabolic Dysregulation and Novel Therapeutic Treatments in ME/CFS and Long COVID
脂肪体衍生细胞因子Upd2调控果蝇气管干细胞的有序迁移	Dong, P.	PDF	N/A	Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila
更快速的基于模型的祖先比例估计	Santander, C.	PDF	N/A	Faster model-based estimation of ancestry proportions
可移动元件积累推动南美洲刺蛾物种Hylesia metabus（鳞翅目：天蚕蛾科）基因组大小增加	Perrier, C.	PDF	N/A	Transposable element accumulation drives genome size increase in Hylesia metabus (Lepidoptera: Saturniidae), an urticating moth species from South America
人类大脑祖先条形码	Shibata, D.	PDF	N/A	Human Brain Ancestral Barcodes
鉴定用于神经退行性疾病治疗的新型小分子伴侣激活剂	Ho, A.	PDF	N/A	Identification of novel small molecule chaperone activators for neurodegenerative disease treatment
经济高效的DNA存储技术：DNA活字印刷术	Wang, C.	PDF	N/A	Cost-effective DNA storage with DNA movable type
PINK1的缺失会导致黑质纹状体多巴胺能神经元中依赖年龄的线粒体运输缺陷，这是由于p38 MAPK的异常激活所致。	Zhao, J.	PDF	N/A	Loss of PINK1 causes age-dependent mitochondrial trafficking deficits in nigrostriatal dopaminergic neurons through aberrant activation of p38 MAPK
照亮微生物席的组装：蓝细菌和绿屈挠菌门合作构建光响应生物膜	Bunbury, F.	PDF	N/A	Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms
外毛细胞搅动耳蜗内的液体。	Lee, C.	PDF	N/A	Outer hair cells stir cochlear fluids
Nup107是果蝇（Drosophila melanogaster）中Torso介导的变态转变的关键调控因子。	Kawadkar, J.	PDF	N/A	Nup107 is a crucial regulator of Torso-mediated metamorphic transition in Drosophila melanogaster
在斑马鱼胚胎的自发神经活动中，出生顺序指定了运动回路的招募	Abi Younes, M.	PDF	N/A	Birth order specified recruitment of motor circuits during spontaneous neural activity in zebrafish embryo
NEBULA101：一个用于研究语言能力在行为、大脑结构和功能方面的开放数据集	Rampinini, A. C.	PDF	N/A	NEBULA101: an open dataset for the study of language aptitude in behaviour, brain structure and function
Inpp5e 对光感受器外节维护至关重要	Gupta, M.	PDF	N/A	Inpp5e Is Critical for Photoreceptor Outer Segment Maintenance
基于秀丽隐杆线虫毒性测试的自动化微流控平台	Wu, J.	PDF	N/A	An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans
结构导向的瘿形成微生物分泌组分析提供了对效应子多样性和进化的见解	Mukhopadhyay, S.	PDF	N/A	Structure-guided secretome analysis of gall-forming microbes offers insights into effector diversity and evolution
负电荷，而非必需的磷酸化，是14-3-3蛋白配体识别所必需的	Kamayirese, S.	PDF	N/A	Negative Charges, Not Necessary Phosphorylation, are Required for Ligand Recognition by 14-3-3 Proteins
尼安德特人衍生的变异影响人类疾病位点的颅面增强子活性	Uttley, K.	PDF	N/A	Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus
在右美托咪定诱导意识丧失期间大脑连接性和神经血管动力学的变化	Fotiadis, P.	PDF	N/A	Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness
在观察动作时，空间信息和解剖信息的处理具有不同的时序	Waltzing, B. M.	PDF	N/A	Separate timescales for spatial and anatomical information processing during action observation
成年大鼠的多重情境辨别：性别差异与厌恶记忆的时间依赖性泛化动态	Alves, F. N. L.	PDF	N/A	Multiple context discrimination in adult rats: sex variability and dynamics of time-dependent generalization of an aversive memory
APOE基因型和生物年龄影响与生物能量代谢相关的多组学关联	Ellis, D. S.	PDF	N/A	APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics
中间普雷沃菌的蛋白酶interpain A促进人舌鳞状细胞癌细胞增殖和迁移	Chang, S.-M.	PDF	N/A	The protease interpain A of Prevotella intermedia promotes human OSCC cells proliferation and migration
早衰症中层粘连蛋白的相行为与解离动力学：聚合物模型研究	Hameed, H. A.	PDF	N/A	Phase Behavior and Dissociation Kinetics of Lamins in a Polymer Model of Progeria
Metagenomics-Toolkit：灵活高效的基于云的宏基因组学工作流程，具备机器学习驱动的资源分配功能	Belmann, P.	PDF	N/A	Metagenomics-Toolkit: The Flexible and Efficient Cloud-Based Metagenomics Workflow featuring Machine Learning-Enabled Resource Allocation
Gb3三糖基化外泌体作为志贺毒素1型的新型中和剂	Mikolajczyk, K.	PDF	N/A	Gb3 trisaccharide-bearing exosomes as a novel neutralizer for Shiga toxin type 1
CD90识别出具有不同激活和静息维持模式的肌肉干细胞的不同亚群	Kheir, E.	PDF	N/A	CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance
全面的蛋白质组学特征描述了高尔基体内运输中间体	Sumya, F. T.	PDF	N/A	Comprehensive Proteomic Characterization of Intra-Golgi Trafficking Intermediates
系统性炎症和淋巴细胞激活先于类风湿性关节炎	He, Z.	PDF	N/A	Systemic inflammation and lymphocyte activation precede rheumatoid arthritis
利用改良的群体分离分析法鉴定出芽殖酵母铜抗性中的上位性和隐性数量性状位点	Buzby, C.	PDF	N/A	Epistasis and cryptic QTL identified using modified bulk segregant analysis of copper resistance in budding yeast
时空转录组分析揭示了发育过程中分子梯度模式以及沿耳蜗轴的音调组织结构。	Yan, M.	PDF	N/A	Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along cochlear axis
最佳竞争者：互利共生者（如传粉者）的吸引力与选择之间的平衡推动了促进作用，并可能促进作物传粉。	Dornhaus, A.	PDF	N/A	Optimal competitors: the balance of attraction and choices of mutualists, like pollinators, drives facilitation and may promote crop pollination
RBFOX1缺陷的纠正能够修复亨廷顿病的错误剪接并减轻病理	Lozano-Munoz, D.	PDF	N/A	Correction of RBFOX1 deficit rescues Huntington's disease mis-splicing and pathology
丛枝菌根真菌基因型和核组织作为宿主植物营养获取和稳定碳捕获的驱动因素	Ferguson, R.	PDF	N/A	Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon capture
加拿大科学研究生的津贴低于贫困线。	Fraass, A. J.	PDF	N/A	Canadian science graduate stipends lie below the poverty line
使用荧光图像中的不均匀背景减除法进行即时早期基因表达神经元的自动细胞检测	Osanai, H.	PDF	N/A	Automated cell detection for immediate early gene-expressing neurons using inhomogeneous background subtraction in fluorescent images
南非2024年猴痘分子流行病学初步报告	Featherston, J.	PDF	N/A	Preliminary report on the molecular epidemiology of mpox, South Africa 2024
scLong：一种拥有十亿参数的基础模型，用于在单细胞转录组学中捕捉长程基因上下文	Bai, D.	PDF	N/A	scLong: A Billion-Parameter Foundation Model for Capturing Long-Range Gene Context in Single-Cell Transcriptomics
以少求多：基于模拟的推断使扩散加权磁共振成像在极短的采集时间内实现高精度	Eggl, M. F.	PDF	N/A	More with less: Simulation-based inference enables accurate diffusion-weighted MRI with minimal acquisition time
持续的感觉运动转换增强了猕猴运动皮层神经动力学对扰动的鲁棒性	Zheng, C.	PDF	N/A	Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex
扩展杏仁核促肾上腺皮质激素释放激素神经元调控草原田鼠（Microtus ochrogaster）在社会挫败后形成的配对结合中的性别二态性变化	Tickerhoof, M. C.	PDF	N/A	Extended amygdala corticotropin-releasing hormone neurons regulate sexually dimorphic changes in pair bond formation following social defeat in prairie voles (Microtus ochrogaster)
CircAge：一个综合性的跨物种和组织的老化相关环状RNA资源	Dong, X.	PDF	N/A	CircAge: A Comprehensive Resource for Aging-Associated Circular RNAs Across Species and Tissues
整合知识、组学和人工智能，开发患者特异性的虚拟化身	Bekkar, A.	PDF	N/A	Integrating knowledge, omics and AI to develop patient-specific virtual avatars
基于图自编码器和StrNN的心力衰竭患者死亡率因果分析	Kim, D.	PDF	N/A	Graph Autoencoder and StrNN based Causal Analysis of Mortality in Heart Failure Patients
抑制富含丝氨酸和精氨酸的剪接因子3可诱导表皮分化并降低皮肤鳞状细胞癌风险	Donohue, I. M.	PDF	N/A	Inhibition of serine and arginine-rich splicing factor 3 induces epidermal differentiation and decreases cutaneous squamous cell carcinoma risk
TRPV4钙通透性通道有助于主动脉狭窄中的瓣膜硬化	Dutta, B.	PDF	N/A	TRPV4 calcium-permeable channel contributes to valve stiffening in aortic stenosis
对大脑中非言语听觉记忆的系统性及元分析回顾	Campo, F. F.	PDF	N/A	A systematic and meta-analytic review of non-verbal auditory memory in the brain
偏头痛与内感受之间的关系：准确性正常但感觉和行为改变	Jones, S.	PDF	N/A	Relationships between migraine and interoception: normal accuracy but altered sensibility and behaviour
多结果生存数据的惩罚降秩回归支持年龄相关疾病的共同代谢风险评分	Sluiskes, M. H.	PDF	N/A	Penalized reduced rank regression for multi-outcome survival data supports a common metabolic risk score for age-related diseases
用于跨物种测试膜定位标签的工具包	Karapidaki, I.	PDF	N/A	A toolkit for testing membrane localisation tags across species
耦合人地系统建模趋势：范围综述	Thampi, V.	PDF	N/A	Trends in Coupled Human-Environment Systems Modelling: A Scoping Review
传统草药提取物对抗多药耐药细菌的有效性：综述	Pane, Y. S.	PDF	N/A	Effectiveness of Traditional Herbal Extracts Against Multidrug-Resistant Bacteria: A Review
海马体OLM中间神经元调节CA1位置细胞的可塑性和重映射	Udakis, M.	PDF	N/A	Hippocampal OLM interneurons regulate CA1 place cell plasticity and remapping
γ-分泌酶功能障碍谱作为PSEN1、PSEN2和APP致病基因中ADAD发病年龄的统一预测因子	Gutierrez Fernandez, S.	PDF	N/A	Spectrum of gamma-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes
气候变化塑造了亚高山草地实验中的物种丰富度-均匀度关系	Muehlbauer, L. K.	PDF	N/A	Climate change shapes richness-evenness relationships in a subalpine grassland experiment
个体间基因表达的变异性意味着大脑偏倚基因在各器官中具有稳定的调控机制。	Bucao, C. F.	PDF	N/A	Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs
系统性基因组-表观基因组分析揭示了胃肠道腺癌中与MYB相关的超级增强子的谱系特异性及功能意义	Li, F.	PDF	N/A	Systemic genome-epigenome analysis captures the lineage specificity and functional significance for MYB associated super-enhancer in gastrointestinal adenocarcinoma
GHT-SELEX 展示了许多人源转录因子出乎意料的高内在序列特异性及复杂的 DNA 结合特性。	Jolma, A.	PDF	N/A	GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors
大量未知的人类转录因子与基因组暗物质结合	Razavi, R.	PDF	N/A	Extensive binding of uncharacterized human transcription factors to genomic dark matter
一种综合方法用于优先筛选牛复杂性状的候选因果基因	Ghoreishifar, M.	PDF	N/A	An integrative approach to prioritize candidate causal genes for complex traits in cattle
gen3DNet：一个用于生成三维网络模型的R包	Mollah, S.	PDF	N/A	gen3DNet: An R Package for Generating 3D Network Models
scExplorer：一个全面的单细胞RNA测序数据分析网络服务器	Galaz, S. F. H.	PDF	N/A	scExplorer: A Comprehensive Web Server for Single-Cell RNA Sequencing Data Analysis
虚拟实验室：AI智能体设计新型SARS-CoV-2纳米抗体并经实验验证	Swanson, K.	PDF	N/A	The Virtual Lab: AI Agents Design New SARS-CoV-2 Nanobodies with Experimental Validation
一种计算上非结构化蛋白质的简单方法：一些发现	Powell, A.	PDF	N/A	A simple method for computationally unstructuring proteins: some findings
单细胞多组学分析揭示了NPM1突变型AML克隆演化中的基因型-免疫表型关系	Drucker, M.	PDF	N/A	Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis
通过呼出气颗粒（PExA）收集的远端肺液态活检中的microRNA和非靶向蛋白质组分析揭示了细胞外囊泡的存在。	Bonatti, M.	PDF	N/A	microRNA and non-targeted proteome analysis of liquid biopsies from the distal lung collected by Particles in Exhaled Air (PExA) reveals presence from extracellular vesicles
工程化和进化型自养大肠杆菌菌株的系统级表征	Yilmaz, S.	PDF	N/A	System-level characterization of engineered and evolved formatotrophic E. coli strains
调控蛋白质在十种人类癌症类型中丰度的主调控因子	Wang, Z.	PDF	N/A	Master regulators governing protein abundance across ten human cancer types
DIA-BERT：用于增强DIA蛋白质组学数据分析的端到端预训练变换器模型	Liu, Z.	PDF	N/A	DIA-BERT: pre-trained end-to-end transformer models for enhanced DIA proteomics data analysis
初级视觉皮层中运动的潜在编码	Cosnier-Horeau, C.	PDF	N/A	Latent encoding of movement in primary visual cortex
SIMPL：从行为中优化神经表征的扩展且简便的方法	George, T. M.	PDF	N/A	SIMPL: Scalable and hassle-free optimization of neural representations from behaviour
尼莫地平在体外可减少小胶质细胞的激活，这一结论通过形态学表型、吞噬活性和新一代RNA测序得以证实。	Pesti, I.	PDF	N/A	Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and next generation RNA sequencing
高级视觉皮层的组织与视觉信息而非抽象的语言信息相一致。	Shoham, A.	PDF	N/A	The organization of high-level visual cortex is aligned with visual rather than abstract linguistic information
ConvexGating 从单细胞流式细胞数据中的聚类推断出门控策略。	Friedrich, V. D.	PDF	N/A	ConvexGating infers gating strategies from clusters in single cell cytometry data
单核苷酸开关赋予假单胞菌噬菌体抗性	Vacheron, J.	PDF	N/A	Single nucleotide switches confer bacteriophage resistance to Pseudomonas protegens
疫苗诱导和混合免疫对澳大利亚昆士兰州两个队列中关注的SARS-CoV-2变种的保护作用（2021-2022年）。	Parry, R. H.	PDF	N/A	Vaccine-induced and hybrid immunity against SARS-CoV-2 variants of concern in two cohorts in Queensland, Australia (2021-2022).
秀丽隐杆线虫（C. elegans）中的体细胞性腺形态发生需要通过HBL-1作用的异时性通路。	Minutillo, M.	PDF	N/A	Somatic gonad morphogenesis in C. elegans requires the heterochronic pathway acting through HBL-1
母体运动以一种与运动方式特异性的方式改变胎盘蛋白质组	Jevtovic, F.	PDF	N/A	Maternal exercise alters placental proteome in an exercise mode-specific manner
通过BaFOMS视角解读生态流行病学系统中的记忆模式：一种贝叶斯分数阶模型选择方法	Mestry, D. V.	PDF	N/A	Deciphering Memory Patterns in Eco-Epidemiological systems through the lens of BaFOMS: A Bayesian Fractional Order Model Selection Method
单配制果蝇会重新交配：热暴露对交配行为和繁殖力的可塑性和进化影响——以暗色果蝇为例	Grandela, A.	PDF	N/A	Monandrous flies do remate: plastic and evolutionary consequences of heat exposure on mating behaviour and fertility in Drosophila subobscura
对在COVID-19第一波期间导致医院爆发的持久性、耐唑类药物的C. parapsilosis菌株的基因组特征分析	Vumbaca, M.	PDF	N/A	Genomic characterization of a persistent, azole-resistant C. parapsilosis strain responsible for a hospital outbreak during the first COVID-19 wave
跨平台DNA基序发现与基准测试：探索研究不足的人类转录因子结合特异性	Vorontsov, I. E.	PDF	N/A	Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors
QT-WEAVER：尽管基因树估计存在误差，校正四重分布仍能改善系统基因组学分析	Hasan, N. B.	PDF	N/A	QT-WEAVER: Correcting quartet distribution improves phylogenomic analyses despite gene tree estimation error
GRIP：用于液相色谱梯度保留时间预测的物理信息神经网络	George, K.	PDF	N/A	GRIP: physics-informed neural network for gradient retention time prediction in liquid chromatography
在女性中，CETP表达在冷暴露和体温中性环境下均能提高身体代谢率，从而有助于形成更为瘦削的表型。	Castelli, J. Z.	PDF	N/A	CETP expression in females increases body metabolism under both cold exposure and thermoneutrality contributing to a leaner phenotype
使用分布式仿真在神经网络中建模神经元-星形胶质细胞相互作用	Jiang, H.-J.	PDF	N/A	Modeling neuron-astrocyte interactions in neural networks using distributed simulation
边缘海的连通性与种群结构——综述	Henriksson, S.	PDF	N/A	Connectivity and population structure in a marginal sea - a review
在植物协同非自体识别自交不亲和系统中协调冲突的选择压力	Jangid, A.	PDF	N/A	Reconciling conflicting selection pressures in the plant collaborative non-self recognition self-incompatibility system
解析肺癌恶性肿瘤中复杂基因组重排的进化历程	Hu, X.	PDF	N/A	Deconstructing evolutionary histories of complex genomic rearrangements in lung malignancies
通过上皮微生理分析平台构建的人类干细胞衍生的肾集合管模型：Epi-MAP	Hong, S.	PDF	N/A	Human Stem Cell-derived Kidney Collecting Duct Model via Epithelial Microphysiological Analysis Platform: Epi-MAP
血-肿瘤屏障类器官重现了胶质母细胞瘤微环境，并实现了治疗递送的高通量建模。	Cho, C.-F.	PDF	N/A	Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery
血-肿瘤屏障类器官再现了胶质母细胞瘤微环境，并实现了治疗递送的高通量建模。	Zhuang, P.	PDF	N/A	Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery
微生物群应激诱导miRNA的鉴定，与慢性鼻窦炎（CRS）的网络关系及表达	Wei, B.	PDF	N/A	Identification of Stress-induced miRNA of Microbial flora, networking, expression with chronic rhinosinusitis (CRS)
通过基因过表达和编辑，以果实表皮特异性nsLTP启动子为目标，针对番茄果实角质层进行研究	Alonso, M.	PDF	N/A	Targeting the tomato fruit cuticle by gene overexpression and editing with the fruit epidermis-preferential nsLTP promoter
人类单个神经元的活动受到基底外侧杏仁核内源性θ脉冲刺激的调控	Campbell, J. M.	PDF	N/A	Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala
通过内在运动节奏的频率失谐实现皮层手部和言语区域的功能分离。	Anastasopoulou, I.	PDF	N/A	Functional segregation of cortical hand and speech areas by frequency detuning of an intrinsic motor rhythm.
饮食诱导的肥胖与慢性压力在小鼠更年期模型中的相互作用	Knox, N.	PDF	N/A	The Interaction Of Diet-Induced Obesity And Chronic Stress In A Mouse Model Of Menopause
经训练的先天免疫系统减弱了巨噬细胞对癌细胞的吞噬作用	Chatzis, A.	PDF	N/A	Trained innate immunity attenuates macrophage efferocytosis of cancer cells
PGE2-cAMP和IFN-γ信号通路对TNF反应和IL-1b+巨噬细胞的调控作用	Sokhi, U. K.	PDF	N/A	Opposing Regulation of TNF Responses and IL-1b+ Macrophages by PGE2-cAMP and IFN-g Signaling
基于质谱的抗体测序系统性基准测试揭示了方法学偏差	Chernigovskaya, M.	PDF	N/A	Systematic benchmarking of mass spectrometry-based antibody sequencing reveals methodological biases
转录因子GABPA是原始多能性的主调控因子	Zhou, C.	PDF	N/A	The transcription factor GABPA is a master regulator of naive pluripotency
在原代人类软骨细胞中拼接响应的QTLs，识别出潜在的骨关节炎风险基因	Byun, S.	PDF	N/A	Response splicing QTLs in primary human chondrocytes identifies putative osteoarthritis risk genes
LOL-EVE：基于进化序列预测启动子变体效应	Shearer, C.	PDF	N/A	LOL-EVE: Predicting Promoter VariantEffects from Evolutionary Sequences
通过囊泡出口实现的非破坏性转录组学	Armbrust, N.	PDF	N/A	Non-destructive transcriptomics via vesicular export
泛癌研究：从原发肿瘤到转移瘤的信号系统转变	Zhou, W.	PDF	N/A	Pan-cancer study on transition of signaling systems from primary to metastatic tumors
电荷调节和离子核内环境对核小体核心颗粒的影响	Nap, R. J.	PDF	N/A	The Impact of Charge Regulation and Ionic Intranuclear Environment on the Nucleosome Core Particle
空间转录组学揭示了急性髓系白血病在髓外和髓内组织中的炎症和转分化状态	Dasdemir, E.	PDF	N/A	Spatial Transcriptomics Reveals Inflammation and Trans-differentiation States of Acute Myeloid Leukemia in Extramedullary and Medullary Tissues
星形胶质细胞-神经元共培养的3D肿瘤球体模型用于抗癌药物筛选	Murugappan, S.	PDF	N/A	Astrocyte-Neuron co-cultured 3D tumor spheroid model for Anti-cancer Drug Screening
单手和双手运动学习过程中微分贝塔和伽马活动的调制	Wu, M.	PDF	N/A	Differential beta and gamma activity modulation during unimanual and bimanual motor learning
C3aR1 在 β 细胞上的作用增强了 β 细胞的功能和生存能力。	Lima, R.	PDF	N/A	C3aR1 on β cells enhances β cell function and survival
Spotiphy使得在整个切片上实现单细胞空间全转录组学成为可能	Yang, J.	PDF	N/A	Spotiphy enables single-cell spatial whole transcriptomics across the entire section
黑素浓缩激素投射到伏隔核会增强食物消费的奖赏价值，但不会引发进食或快速眼动睡眠。	Furman, K. L.	PDF	N/A	Melanin concentrating hormone projections to the nucleus accumbens enhance the reward value of food consumption and do not induce feeding or REM sleep
前额叶皮层编码与运动解耦的行为状态	Rautio, I. V.	PDF	N/A	Prefrontal cortex encodes behavior states decoupled from movement
结核分枝杆菌在碳饥饿条件下的蛋白质组学特征分析	Devlin, K. L.	PDF	N/A	Proteomic characterization of Mycobacterium tuberculosis subjected to carbon starvation
生物边界条件调控肺泡细胞对烟曲霉孢子的内化作用	Schiefermeier-Mach, N.	PDF	N/A	Biological Boundary Conditions Regulate the Internalization of Aspergillus Fumigatus Conidia by Alveolar Cells
Sigma因子作为潜在靶点以提高重组蛋白表达	Pohlen, L.	PDF	N/A	Sigma factors as potential targets to enhance recombinant protein expression
西班牙小型陆生哺乳动物粪便样本中DNA病毒的完整基因组	Buigues, J.	PDF	N/A	Complete genomes of DNA viruses in faecal samples from small terrestrial mammals in Spain
资源环境塑造了人类阴道微生物群的组成和稳定性。	Kamiya, T.	PDF	N/A	Resource landscape shapes the composition and stability of the human vaginal microbiota
口服衣原体疫苗对宿主肠道微生物群和代谢物组成的影响	Huang, Y.	PDF	N/A	Impact of oral Chlamydia Vaccination on Host Gut Microbiome and Metabolites Composition
一种用于多种致病真菌的体内烧伤伤口感染模型。	Mercado-Soto, N.	PDF	N/A	A conserved in vivo burn wound infection model for diverse pathogenic fungi.
盐度影响了现代潮间带微生物岩的微生物碳酸盐沉淀机制	Hsieh, Y. E.	PDF	N/A	Salinity impacted microbial carbonate precipitation mechanisms of modern microbialites in peritidal zone
鉴定出一种新的菜豆金色花叶病毒β卫星DNA，并发现与阿萨姆邦Bhut Jolokia辣椒卷叶病相关的病毒复合体	Saikia, R.	PDF	N/A	Identification of a novel begomovirus betasatellite and occurrence of a viral complex associated with leaf curl disease in Bhut Jolokia in Assam
通过直接检测RNA氧化来定量亚细胞RNA定位	Lo, H.-Y. G.	PDF	N/A	Quantification of subcellular RNA localization through direct detection of RNA oxidation
通过多重邻近标记技术进行染色质结构图谱绘制	Delamarre, A.	PDF	N/A	Chromatin architecture mapping by multiplex proximity tagging
关于代码本的观点：未表征人类转录因子的序列特异性	Jolma, A.	PDF	N/A	Perspectives on Codebook: sequence specificity of uncharacterized human transcription factors
使用meSMiLE-seq技术鉴定甲基化敏感的人类转录因子	Gralak, A. J.	PDF	N/A	Identification of methylation-sensitive human transcription factors using meSMiLE-seq
纤维碎片化在种子种群中产生了多样性	Pedrola, J. A.	PDF	N/A	Fibril fragmentation generates diversity in seed population
蛋白质病原性在单聚集体水平上的分子决定因素	Urbanek, A.	PDF	N/A	Molecular determinants of protein pathogenicity at the single-aggregate level
脊椎动物R2逆转录转座子复合体在目标引导逆转录过程中的结构及第二链切割后的结构	Thawani, A.	PDF	N/A	Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking
压力改变细菌生物分子凝聚物材料状态，并将其功能从mRNA降解转变为储存	Ortiz-Rodrlguez, L. A.	PDF	N/A	Stress Changes the Bacterial Biomolecular Condensate Material State and Shifts Function from mRNA Decay to Storage
使用光学光热红外光谱技术检测未染色组织中的未标记微塑料和纳米塑料	Duswald, K.	PDF	N/A	Detection of Unlabeled Micro- and Nanoplastics in Unstained Tissue with Optical Photothermal Infrared Spectroscopy
针对非同源末端连接与辐射在极高风险SHH型髓母细胞瘤中的合成致死性	DeCarlo, A.	PDF	N/A	Targeting synthetic lethality between non-homologous end joining and radiation in very high-risk SHH medulloblastoma
开发评估YAP-TEAD抑制剂潜力的流程 - 直接抑制TEAD可抑制NF2突变型间皮瘤模型中的癌细胞生长	Cunningham, R.	PDF	N/A	Development of a pipeline to evaluate YAP-TEAD inhibitor potential - direct TEAD inhibition represses cancerous growth in a NF2-mutant model of mesothelioma
突变型RIT1与YAP合作，推动类似上皮间质转化的肺癌状态	Rominger, M. C.	PDF	N/A	Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state
TLL1敲低通过增强抗肿瘤免疫抑制前列腺癌进展	hao, j.	PDF	N/A	TLL1 knockdown attenuates prostate cancer progression by enhancing antitumor immunity
TCR-TRANSLATE：生成真实抗原特异性T细胞受体序列的条件生成	Karthikeyan, D.	PDF	N/A	TCR-TRANSLATE: Conditional Generation of Real Antigen Specific T-cell Receptor Sequences
甲型流感病毒转录生成加帽的cRNA，这些cRNA能够激活RIG-I。	Elshina, E.	PDF	N/A	Influenza A virus transcription generates capped cRNAs that activate RIG-I
代谢见解：芽孢杆菌科微生物诱导方解石形成的机制及其在生物基建筑材料中的应用	Michael, S.	PDF	N/A	Metabolic insights into microbially induced calcite formation by Bacillaceae for application in bio-based construction materials
使用新开发的微卫星分型检测方法研究阿萨希毛孢子菌分离株的遗传关系	Francisco, E. C.	PDF	N/A	Investigating the genetic relationship of Trichosporon asahii isolates using a newly developed microsatellite typing assay
解析糖尿病足溃疡的分子足迹：计算机辅助发现关键蛋白质和微RNA特征	Chudasama, J. M.	PDF	N/A	Unravelling the Molecular Footprints of Diabetic Foot Ulcers: In Silico Discovery of Key Protein and MicroRNA Signatures
用于植物基因组大小估计的流式细胞术标准的重新校准	Soni, A.	PDF	N/A	Re-calibration of flow cytometry standards for plant genome size estimation
通过针对与冠状动脉疾病相关的基因，绘制平滑肌细胞中的动脉粥样硬化机制图谱	Albarran-Juarez, J.	PDF	N/A	Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease
表面重塑和细胞-基质相互作用的反转是霍乱弧菌生物膜中社群识别和分散的基础	Moreau, A. P.	PDF	N/A	Surface remodeling and inversion of cell-matrix interactions underlies community recognition and dispersal in Vibrio cholerae biofilms
通过招募特异性泛素连接酶研究蛋白质降解性	Shade, O.	PDF	N/A	Investigating Protein Degradability through Site-Specific Ubiquitin Ligase Recruitment
脂质驱动的SRC自缔合作用调节其转化能力	Mohammad Jabeen, I.-L.	PDF	N/A	Lipid-driven SRC self-association modulates its transformation capacity
具有变异活性位点的古菌核糖体结构	Nissley, A. J.	PDF	N/A	Structure of an Archaeal Ribosome with a Divergent Active Site
# BioRxiv 2024-11-11 Papers

标题	作者	PDF链接	代码仓库	Title
DAF-16/Foxo通过系统性小RNA途径抑制prg-1 piRNA突变体的跨代不育	Simon, M.	PDF	N/A	DAF-16/Foxo suppresses the transgenerational sterility of prg-1 piRNA mutants via a systemic small RNA pathway
当没有答案比错误的答案更好时：关于批次效应的因果视角	Bridgeford, E. W.	PDF	N/A	When no answer is better than a wrong answer: a causal perspective on batch effects
为什么棕色的幽灵在夜晚鸣叫	Oboti, L.	PDF	N/A	Why the brown ghost chirps at night
黄素二铁蛋白通过依赖pH值的方式与类囊体膜结合，以进行由铁氧还蛋白-1驱动的O2光还原反应。	Nikkanen, L.	PDF	N/A	Flavodiiron proteins associate pH-dependently with the thylakoid membrane for ferrdoxin-1 powered O2 photoreduction
由于不适当继承的组蛋白甲基化导致的异位转录可能会干扰终末分化细胞的正在进行的功能。	Rodriguez, J. D.	PDF	N/A	Ectopic transcription due to inappropriately inherited histone methylation may interfere with the ongoing function of terminally differentiated cells
在不同啮齿动物杂交中，不同的复杂调控表型是导致杂交雄性不育的潜在原因。	Hunnicutt, K. E.	PDF	N/A	Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses
重新发现卵巢网：卵巢的分泌辅助结构	Anbarci, D. N.	PDF	N/A	Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary
使用基于聚类的排列检验来估计MEG/EEG起始时间：有多糟糕？	Rousselet, G. A.	PDF	N/A	Using cluster-based permutation tests to estimate MEG/EEG onsets: how bad is it?
Celsr3突变小鼠中的刻板行为与纹状体D3多巴胺受体的改变有关。	Cadeddu, R.	PDF	N/A	Tic-related behaviors in Celsr3 mutant mice are contributed by alterations of striatal D3 dopamine receptors
低盐度会破坏糖海带（Saccharina latissima，褐藻门）的细菌群落。	Schenk, S.	PDF	N/A	Low salinity destabilizes the bacterial community of sugar kelp, Saccharina latissima (Phaeophyceae)
在感知决策过程中，猕猴大脑的大规模新皮层网络中分布式证据积累	Zou, L.	PDF	N/A	Distributed evidence accumulation across macaque large-scale neocortical networks during perceptual decision making
Id 位点的共同祖先：染色体重排与多基因可能性	Sharma, A.	PDF	N/A	Common Ancestry of the Id Locus: Chromosomal Rearrangement and Polygenic Possibilities
控制斑马鱼内胚层形成和左右模式形成的重复SOX因子的功能分化分子基础	Johal, S.	PDF	N/A	The molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish
担子菌类真菌菌丝直径的瞬时变化	Mazheika, I. S.	PDF	N/A	Instantaneous change in hyphal diameter in basidiomycete fungi
探索基于OPM-MEG的多变量传递熵的有向连接模式	Pedersen, M.	PDF	N/A	Exploring Directed Connectivity Patterns of OPM-MEG with Multivariate Transfer Entropy
全基因组关联研究揭示了与杂交大鼠海洛因易感性相关的痛觉和阿片类药物消耗行为的多个基因位点	Kuhn, B. N.	PDF	N/A	Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats
GDFold2：一个快速且可并行化的蛋白质折叠环境，具有自由定义的目标函数	Mi, T.	PDF	N/A	GDFold2: a fast and parallelizable protein folding environment with freely defined objective functions
轴突细胞器因AP-4复合体功能丧失而积聚，导致阿尔茨海默病小鼠模型中淀粉样斑块病理和胶质增生的加剧。	Orlowski, A.	PDF	N/A	Axonal organelle buildup from loss of AP-4 complex function causes exacerbation of amyloid plaque pathology and gliosis in Alzheimers disease mouse model
使用MIDAS v3和StrainPGC准确估计宏基因组数据中的种内微生物基因含量变异	Smith, B. J.	PDF	N/A	Accurate estimation of intraspecific microbial gene content variation in metagenomic data with MIDAS v3 and StrainPGC
急性髓系白血病线粒体通过水解ATP来抵抗化疗	Hagen, J. T.	PDF	N/A	Acute myeloid leukemia mitochondria hydrolyze ATP to resist chemotherapy
星形胶质细胞转谷氨酰胺酶2的药理学抑制作用有助于促进神经支持性星形胶质细胞反应表型的表达，这与组蛋白乙酰化水平升高有关。	Delgado, T.	PDF	N/A	Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation
parafac4microbiome：使用平行因子分析对纵向微生物组数据进行探索性分析	van der Ploeg, G. R.	PDF	N/A	parafac4microbiome: Exploratory analysis of longitudinal microbiome data using Parallel Factor Analysis
利用铁羟基氧化铁增强的分层磁共振成像技术绘制灵长类大脑中的血管网络结构	Autio, J. A.	PDF	N/A	Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI
解析急性运动缺陷和由小脑输出丧失引起的适应性反应	Sinha, N.	PDF	N/A	Disentangling acute motor deficits and adaptive responses evoked by the loss of cerebellar output
一个用于系统性和可重复性研究结构-功能关系的连接组操作框架，通过模拟实现。	Pokorny, C.	PDF	N/A	A connectome manipulation framework for the systematic and reproducible study of structure-function relationships through simulations
从鼠标视觉皮层活动重建电影	Bauer, J.	PDF	N/A	Movie reconstruction from mouse visual cortex activity
海洋环节动物多室草苔虫的基因组资源	Mutemi, K. N.	PDF	N/A	A genome resource for the marine annelid Platynereis dumerilii
非自主性胰岛素信号传导可延缓秀丽隐杆线虫生殖系干细胞和祖细胞的有丝分裂进程。	Cheng, E.	PDF	N/A	Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells
计算建模揭示了纹状体亚区域特异性多巴胺动态的关键决定因素	Ejdrup, A. L.	PDF	N/A	Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum
在人类和恒河猴中，HIV-1的进化动力学与广泛中和抗体的产生	Shimagaki, K. S.	PDF	N/A	Parallel HIV-1 evolutionary dynamics in humans and rhesus macaques who develop broadly neutralizing antibodies
蛋白质-蛋白质相互作用对酪氨酸磷酸酶PTP1B的别构调控	Chartier, C. A.	PDF	N/A	Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction
韩国都湖组（中新世）中新发现的金枪鱼标本（属Auxis）	Suh, D.	PDF	N/A	A new tuna specimen (Genus Auxis) from the Duho Formation (Miocene) of South Korea
在微流控芯片上利用人胚胎干细胞衍生的类器官模拟软骨内骨化初期的血管动力学	Kesharwani, A.	PDF	N/A	Modeling vascular dynamics at the initial stage of endochondral ossification on a microfluidic chip using a human embryonic-stem-cell-derived organoid
横断面的脑龄评估在预测未来脑部变化方面存在局限性。	Korbmacher, M.	PDF	N/A	Cross-sectional brain age assessments are limited in predicting future brain change
细胞衍生基质的纳米力学作为胶原蛋白VI相关先天性肌营养不良症的功能读数	White, T.	PDF	N/A	Nanomechanics of cell-derived matrices as a functional read-out in Collagen VI-related Congenital Muscular Dystrophies
Evolvoid：一种用于塑造最佳细胞结构的遗传算法	Mancini, P.	PDF	N/A	Evolvoid: A genetic algorithm for shaping optimal cellular constructs
成年大鼠的多重情境辨别：性别差异及厌恶记忆的时间依赖性泛化动态	Alves, F. N. L.	PDF	N/A	Multiple context discrimination in adult rats: sex variability and dynamics of time-dependent generalization of an aversive memory
LipiDetective - 一种用于识别串联质谱中分子脂质种类的深度学习模型	Wuerf, V.	PDF	N/A	LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra
多巴胺和皮质iPSC衍生的神经元在不同的帕金森病突变中显示出溶酶体和线粒体功能障碍的差异：这对蛋白质沉积与选择性细胞丢失的影响	Chedid, J.	PDF	N/A	Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
在刚地弓形虫入侵过程中，宿主细胞质膜的穿孔需要棒状体胞吐作用。	Male, F.	PDF	N/A	Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis
代谢物营养图谱指南 - 揭示与疾病病因相互作用的代谢物营养图谱	Wuerf, V.	PDF	N/A	MeNu GUIDE - a metabolite nutrition graph to uncover interactions with disease etiology
一种跨动物和环境的普遍海马记忆编码	Wirtshafter, H. S.	PDF	N/A	A universal hippocampal memory code across animals and environments
智能分布式数据工厂：面向主动学习驱动分子数据采集的志愿者计算平台	Ghukasyan, T.	PDF	N/A	Smart Distributed Data Factory: Volunteer Computing Platform for Active Learning-Driven Molecular Data Acquisition
洗牌：扩展合成生物学工具箱以适应类似洗牌重组系统	Katalinic, J.	PDF	N/A	Do the shuffle: Expanding the synthetic biology toolkit for shufflon-like recombination systems
使用多重竞争性等位基因特异性PCR（mxKASP）基因分型确定合子性	de Visser, M. C.	PDF	N/A	Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping
保守的基因内容和独特的系统发育历史特征了Triturus平衡致死系统背后的“bloopergene”	de Visser, M. C.	PDF	N/A	Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system
NewtCap：一种高效的目标捕获方法，用于提升蝾螈科（真蝾螈和新蝾螈）基因组研究	de Visser, M. C.	PDF	N/A	NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts)
PAV-spotter：利用信号互相关识别目标捕获数据中的存在/缺失变异	de Visser, M. C.	PDF	N/A	PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data
鲸鱼语言模型（WhaleLM）：利用机器学习在抹香鲸的声音和行为中寻找结构与信息	Sharma, P.	PDF	N/A	WhaleLM: Finding Structure and Information in Sperm Whale Vocalizations and Behavior with Machine Learning
基因组证据表明，Triturus蝾螈中的平衡致死系统起源于一次瞬间的物种形成事件。	France, J. M.	PDF	N/A	Genomic evidence suggests the balanced lethal system in Triturus newts originated in an instantaneous speciation event.
使用CSI-TME识别IDH突变型胶质瘤肿瘤微环境中预后细胞状态相互作用	Singh, A.	PDF	N/A	Identifying Prognostic Cell State Interactions in the Tumor Microenvironment of IDH-Mutant Gliomas Using CSI-TME
底物利用和交叉喂养协同作用决定微生物群对病原体入侵的抵抗力	Yang, X.	PDF	N/A	Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion
BNT162b2 JN.1-和KP.2-适应型COVID-19疫苗的免疫学和生物物理特性	Chen, W.	PDF	N/A	Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines
对两种稀有鲸类物种解剖学的贡献：沙漏海豚（Lagenorhynchus cruciger）与眼镜海豚（Phocoena dioptrica）	Graic, J.-M.	PDF	N/A	A Contribution To The Anatomy Of Two Rare Cetacean Species: The Hourglass Dolphin (Lagenorhynchus cruciger) And The Spectacled Porpoise (Phocoena dioptrica)
通过泛基因组学鉴定和表征古菌假肽聚糖生物合成基因	Lupo, V.	PDF	N/A	Identification and Characterization of Archaeal Pseudomurein Biosynthesis Genes through Pangenomics
基于图像的低嵌合体体细胞移动元件插入检测的DNA测序编码	Tan, M.	PDF	N/A	Image-based DNA Sequencing Encoding for Detecting Low-Mosaicism Somatic Mobile Element Insertions
子宫内膜蜕膜化反应的停滞决定了流产的复发风险	Muter, J.	PDF	N/A	Stalling of the endometrial decidual reaction determines the recurrence risk of miscarriage
ERP和神经振荡能否用于区分在生态学上有效的运动模型中熟练和不熟练玩家的表现？	Winstanley, M.	PDF	N/A	Can ERPs and neural oscillations be used to differentiate skilled and unskilled player performance in an ecologically valid sporting model?
Tidyplots 赋予生命科学家通过简单代码实现数据可视化的能力。	Engler, J. B.	PDF	N/A	Tidyplots empowers life scientists with easy code-based data visualization
血管转录因子TMO5调控PIN1极性及器官发生：在芽分生组织中作为MONOPTEROS的下游因子	Kareem, A.	PDF	N/A	Vascular Transcription Factor TMO5 Regulates PIN1 Polarity andOrganogenesis Downstream of MONOPTEROS in the Shoot Meristem
纠缠适应性景观通过外适应促进基因调控的进化	Westmann, C. A.	PDF	N/A	Entangled adaptive landscapes facilitate the evolution of gene regulation by exaptation
纠缠适应性景观通过外适应促进基因调控的进化	Westmann, C. A.	PDF	N/A	Entangled adaptive landscapes facilitate the evolution of gene regulation by exaptation
海马、纹状体和眶额皮质对时间信息的同步处理	Shimbo, A.	PDF	N/A	Synchronous processing of temporal information across the hippocampus, striatum, and orbitofrontal cortex
依赖于颗粒细胞的处理对于运动学习至关重要，但对于许多依赖小脑的行为来说却是可有可无的。	Lee, J.-H.	PDF	N/A	Processing reliant on granule cells is essential for motor learning but dispensable for many cerebellar-dependent behaviors
单细胞转录组学揭示埃及伊蚊中肠和脂肪体在吸血后的表达图谱	Vial, T.	PDF	N/A	Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal
对比增强微型CT成像揭示了胎儿女性盆底解剖细节	Aaldijk, D.	PDF	N/A	Contrast-Enhanced Micro-CT Imaging of a Foetal Female Pelvic Floor Reveals Anatomical Details
长读RNA测序揭示了源自人类皮层神经元的转录本特异性调控	Xu, J.	PDF	N/A	Long-Read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons
不同结合模式下的跨峰交联提示SARS-CoV-2抗体中和的补充机制	Nan, X.	PDF	N/A	Distinct Binding Modes of Inter-Spike Cross-Linking Suggest a Supplementary Mechanism for SARS-CoV-2 Antibody Neutralization
ADP-MoA：一种用于筛选抗生素活性及其在铜绿假单胞菌中作用机制的平台	Valencia Morante, E. Y.	PDF	N/A	ADP-MoA: a platform for screening antibiotic activity and their mechanism of action in Pseudomonas aeruginosa
内质网对脂质代谢的感知驱动了PRA家族依赖的COPII囊泡运输调控	Nakazato, M.	PDF	N/A	ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport
在秀丽隐杆线虫中进行的fat-2(wa17)抑制因子筛选揭示了适应多不饱和脂肪酸缺乏的遗传机制	Kaper, D.	PDF	N/A	A fat-2(wa17) suppressor screen in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency
健康人群的综合多组学分析	Visser, C.	PDF	N/A	Comprehensive multi-omics profiling of a healthy human cohort
极化剂AsymPolPOK在完整和裂解的哺乳动物细胞中的稳定性	Lacasga, D.	PDF	N/A	Stability of the polarization agent AsymPolPOK in intact and lysed mammalian cells
线粒体VDAC2的构象可塑性控制其与细胞质蛋白相互作用的动态过程	Rosencrans, W. M.	PDF	N/A	Conformational plasticity of mitochondrial VDAC2 controls the kinetics of its interaction with cytosolic proteins
五聚体尾管蛋白在SPR噬菌体中的组装结构	Zhu, H.	PDF	N/A	Architecture of a pentameric assembly of the tail tube protein in SPR phages
用于预测蛋白质pKa值和离子化状态的KaMLs：树结构是否足够？	Shen, M.	PDF	N/A	KaMLs for Predicting Protein pKa Values andIonization States: Are Trees All You Need?
成像活鼠、死鼠以及处于应激状态的植物的超微弱光子发射	SALARI, V.	PDF	N/A	Imaging Ultraweak Photon Emission from Living and Dead Mice and from Plants under Stress
基于细胞位置的多细胞系统中细胞力学特征评估	Koyama, H.	PDF	N/A	Cell position-based evaluation of mechanical features of cells in multicellular systems
FRET和生物膜干涉技术揭示的NAD+核开关配体结合特性	Conoan Nieves, N. E.	PDF	N/A	Ligand binding characteristics of an NAD+ riboswitch revealed by FRET and biolayer interferometry
Notch信号通路中二价异源三聚体结合的热力学	Cook, C.	PDF	N/A	Thermodynamics of Bivalent Heterotrimer Association in the Notch Signaling Pathway
泛紧密连接蛋白结合分子调节细胞旁屏障的生物物理基础	Ogbu, C. P.	PDF	N/A	Biophysical Basis of Paracellular Barrier Modulation by a Pan-Claudin-Binding Molecule
通过液体振荡使转甲状腺素蛋白聚集	Ritsch, I.	PDF	N/A	Aggregation of Transthyretin by Fluid Agitation
人类和小鼠胰岛素中的一种翻译后半胱氨酸到丝氨酸的转化，产生了一种糖尿病相关的新表位。	Srivastava, N.	PDF	N/A	A post-translational cysteine-to-serine conversion in human and mouse insulin generates a diabetogenic neoepitope
人类活动而非环境因素是台湾地区斯克里普斯孢菌和洛门托孢菌分布的主要驱动力。	Wu, H.-M.	PDF	N/A	Human activity, not environmental factors, drives Scedosporium and Lomentospora distribution in Taiwan
MAGE：异常基因表达的蒙特卡罗方法	Beltran, M.	PDF	N/A	MAGE: Monte Carlo method for Aberrant Gene Expression
使用少样本学习准确预测体细胞系和合子中CRISPR编辑结果	Zheng, W.	PDF	N/A	Accurate prediction of CRISPR editing outcomes in somatic cell lines and zygote with few-shot learning
MOSAIC：微生物组研究分析整合与校正的管道	Fu, C.	PDF	N/A	MOSAIC: A Pipeline for MicrobiOme Studies Analytical Integration and Correction
人类着丝粒和近着丝粒区域中的类昆虫痘病毒长DNA序列	Hondo, E.	PDF	N/A	Entomopoxvirus-like long DNA sequences in human centromeric and peri-centromeric regions
通过计算机模拟识别针对四种感染性不动杆菌的新型共同药物靶点	Rahman, S.	PDF	N/A	In silico Identification of Novel Common Drug Targets Against Four Infectious Acinetobacter Species
结直肠癌III期单细胞空间图谱	Su, A.	PDF	N/A	The single-cell spatial landscape of stage III colorectal cancers
综合蛋白质组-基因组分析揭示了HER2阳性乳腺癌中拉帕替尼耐药的关键生物标志物	Steggall, J.	PDF	N/A	Integrative proteo-genomic profiling uncovers key biomarkers of lapatinib resistance in HER2-positive breast cancer
多巴胺D2受体激动剂可抑制神经内分泌肿瘤血管生成，从而抑制化疗耐药的小细胞肺癌进展	Alam, S. K.	PDF	N/A	Dopamine D2 receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progression
视黄醇浸渍的纳米颗粒通过在小鼠体内对软骨内骨化的位点特异性调节，实现了对骨骼生长的控制。	Matsuoka, M.	PDF	N/A	Retinoid-impregnated nanoparticles enable control of bone growth by site-specific modulation of endochondral ossification in mice
活体木质部细胞编码大量负责维管汁液肽的保守基因家族	Lu, M. R.	PDF	N/A	Living xylem cells encode a large number of conserved gene families responsible for vascular sap peptides
偏移质量载体蛋白质组提高多重单细胞蛋白质组学定量	Cheung, T.	PDF	N/A	Offset mass carrier proteome improves quantification of multiplexed single cell proteomics
通过DBiTplus技术在同一组织切片上整合基于成像和基于测序的空间组学图谱	Enninful, A.	PDF	N/A	Integration of Imaging-based and Sequencing-based Spatial Omics Mapping on the Same Tissue Section via DBiTplus
iPAR：一种在风险人群未知情况下，用于建模和推断疾病传播信息的框架	Catterall, S.	PDF	N/A	iPAR: A framework for modelling and inferring information about disease spread when the populations at risk are unknown
白芷及其根际微生物对空心莲子草处理的生态响应	Huang, Y.	PDF	N/A	Ecological response of Angelica dahurica and its rhizosphere microorganisms to treatments of Alternanthera philoxeroides
描述指猴（Daubentonia madagascariensis）中新种系突变的速率和模式	Versoza, C. J.	PDF	N/A	Characterizing the rates and patterns of de novo germline mutations in the aye-aye (Daubentonia madagascariensis)
指猴（Daubentonia madagascariensis）的结构变异景观	Versoza, C. J.	PDF	N/A	The landscape of structural variation in aye-ayes (Daubentonia madagascariensis)
基于谱系的指猴（Daubentonia madagascariensis）交叉与非交叉图谱	Versoza, C. J.	PDF	N/A	A pedigree-based map of crossovers and non-crossovers in aye-ayes (Daubentonia madagascariensis)
疾病相关调控DNA变异与表皮稳态转录因子	Porter, D. F.	PDF	N/A	Disease-Linked Regulatory DNA Variants and Homeostatic Transcription Factors in Epidermis
研究管理决策在野生火鸡分布范围内亚种杂交中的作用	Beckman, A. K.	PDF	N/A	Investigating the Role of Management Decisions in Subspecies Hybridization Across the Wild Turkey's Range
烟酰胺腺嘌呤二核苷酸、三磷酸腺苷及氧化剂诱导的甘油醛-3-磷酸脱氢酶高阶构象变化的分析	Suzuki, H.	PDF	N/A	Analysis of the high-order conformational changes in glyceraldehyde-3-phosphate dehydrogenase induced by nicotinamide adenine dinucleotide, adenosine triphosphate, and oxidants
多样化的膜结合酰基转移酶的结构统一揭示了一种保守的折叠结构，这种结构定义了跨膜酰基转移酶（Transmembrane Acyl Transferase, TmAT）超家族。	Kinniment-Williams, B. E.	PDF	N/A	Structural unification of diverse membrane-boundacyltransferases reveals a conserved fold that defines the Transmembrane Acyl Transferase (TmAT) superfamily
超声组织消融术和人类多能干细胞衍生的肝球植入术作为先天性代谢性肝病潜在治疗手段的安全性和有效性：在免疫健全的啮齿动物模型中的评估。	Rashidi, H.	PDF	N/A	The safety and efficacy of Ultrasound Histotripsy and human pluripotent stem cell-derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: assessment in an immunocompetent rodent model.
人体器官尺度上的物理玻璃化和纳米升温技术，以实现冷冻保存	Gangwar, L.	PDF	N/A	Physical vitrification and nanowarming at human organ scale to enable cryopreservation
从人类肠道类器官实时测量血清素动态	Bohl, B.	PDF	N/A	Measurement of Real Time Serotonin Dynamics from Human Derived Gut Organoids
儿童唾液DNA甲基化分析中细胞类型异质性的考量：参考面板比较与按估算细胞类型比例的分层	Chan, M. H.-M.	PDF	N/A	Considerations for Cell Type Heterogeneity in Pediatric Salivary DNA Methylation Analyses: Comparison of Reference Panels & Stratification by Estimated Cell TypeProportion
通过序列嵌入进行RNA-蛋白质相互作用分类	Matus, D.	PDF	N/A	RNA-Protein Interaction Classification via Sequence Embeddings
基于类固醇代谢途径的新型深度神经网络模型的生物年龄预测	Wang, Q.	PDF	N/A	Biological age prediction using a novel DNN model based on steroid metabolic pathways
NOODAI：面向网络的多组学数据分析与整合管道的网络服务器	Totu, T.	PDF	N/A	NOODAI: A webserver for network-oriented multi-omics data analysis and integration pipeline
苯并尼达唑抗性克氏锥虫克隆的转录组分析揭示了硝基还原酶I非依赖性抗性机制	Mejia-Jaramillo, A. M.	PDF	N/A	Transcriptomic analysis of benznidazole-resistant Trypanosoma cruzi clone reveals nitroreductase I-independent resistance mechanisms
迁移学习和DNA语言模型提升转录因子结合预测	Aksu, E. D.	PDF	N/A	Transfer learning and DNA language models enhance transcription factor binding predictions
系统识别和表征病毒长链非编码RNA（lncRNA）表明，病毒lncRNA广泛模拟宿主lncRNA的结构。	Fu, P.	PDF	N/A	Systematic identification and characterization of virus lncRNAs suggests extensive structural mimicry of host lncRNAs
一个稳健的工作流程用于基准测试多组学数据的反卷积	Amblard, E.	PDF	N/A	A robust workflow to benchmark deconvolution of multi-omic data
通过双聚类分析揭示英国生物银行中的隐性基因-性状模式	Pividori, M.	PDF	N/A	Uncovering hidden gene-trait patterns through biclustering analysis of the UK Biobank
将结构表示提取到蛋白质序列模型中	Ouyang-Zhang, J.	PDF	N/A	Distilling structural representations into protein sequence models
针对急性髓系白血病干细胞治疗后复发中的IL-1/IRAK1/4信号传导	Ho, T.-C.	PDF	N/A	Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse
健康B细胞：CAR-T细胞免疫疗法的盟友还是对手？	Paixao, E. A.	PDF	N/A	Healthy B cells: allies or adversaries of CAR-T cell immunotherapy?
骨髓微环境特征与HMA耐药MDS患者接受吉达西他滨和阿替利珠单抗治疗后的患者生存相关	Jang, H. J.	PDF	N/A	Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS
HHLA2介导的配体非依赖性c-Met激活驱动肝细胞癌并预测c-MET抑制剂疗效	huang, x.	PDF	N/A	Ligand-independent c-Met activation by HHLA2 drives hepatocellular carcinoma and predicts c-MET inhibitor efficacy
单细胞视频追踪以识别聚集行为	Korsnes, M. S.	PDF	N/A	Video tracking of single cells to identify clustering behaviour
晚更新世巴西东南部灰侏儒鹿摄食策略的千年尺度稳定性。	Hubbe, A.	PDF	N/A	Late Quaternary millennial-scale stability of the feeding strategy of the gray brocket deer in Southeastern Brazil.
绿合成、表征及以Talinum triangulare叶提取物为媒介的Ag-MgO纳米复合材料的潜在抗菌研究	Fonye Nyuyfoni, G.	PDF	N/A	Green synthesis, characterization, and potential antimicrobial studies of Ag-MgO nanocomposites mediated from Talinum triangulare leaf extract
高强度间歇运动对心肺和神经肌肉反应的性别差异	Wilson, H.	PDF	N/A	Sex differences in the cardiopulmonary and neuromuscular response to high-intensity interval exercise
质外体代谢组学揭示了植物-病原体相互作用受氮素供应的调控	Jeridi, R.	PDF	N/A	Apoplast metabolomics reveals that plant-pathogen crosstalk is modulated by nitrogen supply
海生被子植物大叶藻（Zostera marina）中，成花素和抗成花素基因的表达与生殖状态相关。	Nolan, C. T.	PDF	N/A	Florigen and antiflorigen gene expression correlates with reproductive state in a marine angiosperm, Zostera marina
预测化合物在Reactome知识库中的路径参与情况	Huckvale, E. D.	PDF	N/A	Predicting the Pathway Involvement of Compounds Annotated in the Reactome Knowledgebase
密度依赖性如何调节害虫的种群控制：遗传生物防治的视角	Butler, C. D.	PDF	N/A	How population control of pests is modulated by density dependence: The perspective of genetic biocontrol
里海海平面快速下降需要动态时空保护规划，以保持生物多样性保护措施的相关性。	Court, R.	PDF	N/A	Rapid Caspian sea level decline requires dynamic spatio-temporal conservation planning to keep biodiversity protection measures relevant
从高质量的全基因组群体水平数据推断指猴（Daubentonia madagascariensis）的种群历史	Terbot, J. W.	PDF	N/A	Inferring the demographic history of aye-ayes (Daubentonia madagascariensis) from high-quality, whole-genome, population-level data
暗翅蕈蚊Lycoriella ingenua的初级性别比例的母系遗传	Shlyakonova, M.	PDF	N/A	Maternal inheritance of primary sex ratios in the dark-winged fungus gnat Lycoriella ingenua
利用一个拟合良好的进化基准模型，对指猴（Daubentonia madagascariensis）进行全基因组扫描，以寻找近期正选择和平衡选择的证据。	Soni, V.	PDF	N/A	A whole-genome scan for evidence of recent positive and balancing selection in aye-ayes (Daubentonia madagascariensis) utilizing a well-fit evolutionary baseline model
冬小麦产量及产量表型可塑性的遗传调控	Giordano, N.	PDF	N/A	Genetic modulation of yield and phenotypic plasticity of yield in winter wheat
秀丽隐杆线虫中RNA结合与调控蛋白的全景图	Laver, J. D.	PDF	N/A	A global view of the RNA-binding and regulatory protein landscape in Caenorhabditis elegans
基于无细胞RNA中可转座元件特征的子痫前期早期预测	Patel, M.	PDF	N/A	Early Prediction of Preeclampsia Based on Transposable Elements signature in cell-free RNA
巨型鞭蠹（Mastigoproctus giganteus）染色体水平基因组显示出前志留纪全基因组复制的特征。	Kulkarni, S.	PDF	N/A	A chromosome-level genome of the giant vinegaroon Mastigoproctus giganteus exhibits the signature of pre-Silurian whole genome duplication
通过细胞表面和病毒包膜工程的配对增强了对哺乳动物细胞的慢病毒基因递送	Tannir, R.	PDF	N/A	Enhanced lentiviral gene delivery to mammalian cells via paired cell surface and viral envelope engineering
胶质母细胞瘤驱动蛋白酶非依赖性的微胶质细胞外基质侵袭	Chang, C.-W.	PDF	N/A	Glioblastoma Drives Protease-Independent Extracellular Matrix Invasion of Microglia
从单细胞数据推断细胞类型特异性共表达基因	Shan, X.	PDF	N/A	Inferring Cell-Type-Specific Co-Expressed Genes from Single Cell Data
一种适用于深度自上而下蛋白质组学的全窗口数据独立采集方法	Sun, C.	PDF	N/A	A Full Window Data Independent Acquisition Method for DeeperTop-down Proteomics
CelLink：整合具有少量关联特征和不平衡细胞群体的单细胞多组学数据	Luo, X.	PDF	N/A	CelLink: Integrate single-cell multi-omics data with few linked features and imbalanced cell populations
ScisTree2：一种改进的大规模推断细胞谱系树和从噪声单细胞数据进行基因型调用的方法	Zhang, H.	PDF	N/A	ScisTree2: An Improved Method for Large-scale Inference of Cell Lineage Trees and Genotype Calling from Noisy Single Cell Data
来自海洋水柱中全海洋深度原核生物的小蛋白	Wang, Y.	PDF	N/A	Small proteins from prokaryotes in marine water column at full ocean depth
慢性间歇性乙醇通过内源性大麻素非依赖性机制在小鼠中产生痛觉	Miliano, C.	PDF	N/A	Chronic intermittent ethanol produces nociception through endocannabinoid-independent mechanisms in mice
使用氯胺酮作为潜在抗抑郁剂后对两性青春期大鼠的安全性担忧	Jornet-Plaza, J.	PDF	N/A	Safety concerns following the use of ketamine as a potential antidepressant for adolescent rats of both sexes
铜绿假单胞菌吡咯喹啉醌和1-羟基吩嗪对人类鼻上皮细胞内钙离子、线粒体功能及存活率的影响	Thompson, J. C.	PDF	N/A	Effects of Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine on intracellular calcium, mitochondrial function, and viability in human nasal epithelial cells
长期存在于肝脏中的记忆T细胞，其特异性偏向于丰富的子孢子抗原，通过辐射减毒子孢子疫苗驱动疟疾保护作用。	de Menezes, M. N.	PDF	N/A	Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination
长期存活的肝驻留记忆T细胞，其特异性偏向于丰富的子孢子抗原，通过辐射减毒子孢子疫苗驱动疟疾保护作用。	de Menezes, M. N.	PDF	N/A	Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination
鉴定和表征具有高亲和力和强效抗白血病活性的血管活性肠肽受体拮抗剂	Wang, Y.	PDF	N/A	Identification and characterization of vasoactive intestinal peptide receptor antagonists with high-affinity and potent anti-leukemia activity
理解城市食品生产中的授粉：公民科学项目设计中数据验证和参与者反馈的重要性	Nicholls, E.	PDF	N/A	Understanding pollination in urban food production: the importance of data validation and participant feedback for citizen science project design
在气候变化背景下人类改造景观中的生态同步性	Song, Y.	PDF	N/A	Ecological synchrony in human-modified landscapes under a changing climate
环境与个体变异对小型实验种群灭绝时间模式的影响。	Bakker, S.	PDF	N/A	Effects of environmental and individual variation on time patterns of extinction in small experimental populations.
评估密西西比湾（美国）搁浅的大西洋宽吻海豚（Tursiops truncatus）的遗传多样性	Arick, M.	PDF	N/A	Assessment of the Genetic Diversity of Atlantic Bottlenose Dolphin (Tursiops truncatus) Strandings in the Mississippi Sound (USA)
结合便携式样品制备和逆转录环介导等温扩增的柑橘衰退病毒快速比色检测	Liu, C.-W.	PDF	N/A	Rapid colorimetric detection of citrus tristeza virus combining portable sample preparation and reverse transcription-loop mediated isothermal amplification
扩张型心肌病中TITIN变异的含义：整合全外显子测序与分子动力学模拟研究	Mukhopadhyay, A.	PDF	N/A	Implication of TITIN Variations in Dilated Cardiomyopathy: Integrating Whole Exome Sequencing With Molecular Dynamics Simulation Study
综合多组学分析揭示巨噬细胞如何驱动乳腺癌中的免疫抑制并影响临床结果	Azimzade, Y.	PDF	N/A	Integrated multiomics analysis unveils how macrophages drive immune suppression in breast tumors and affect clinical outcomes
scLong：用于捕捉单细胞转录组学中长程基因背景的十亿参数基础模型	Bai, D.	PDF	N/A	scLong: A Billion-Parameter Foundation Model for Capturing Long-Range Gene Context in Single-Cell Transcriptomics
产前砷暴露与胎儿肝脏、心脏、肺和胎盘中基因表达的关系	Rychlik, K. A.	PDF	N/A	Prenatal Arsenic Exposure and Gene Expression in Fetal Liver, Heart, Lung, and Placenta
芹菜油（Apium graveolens）-肉豆蔻酸基微乳体系的体外抗癌、抗炎和抗氧化活性：表征与生物医学应用	Govindaswamy, B.	PDF	N/A	In vitro anti cancer, anti inflammatory and anti oxidant activity of Celery oil (Apium graveolens)-Myristic acid based microemulsion system: Characterization and Biomedical application
多扎格列汀和肠促胰岛素在胰岛素分泌中的性别依赖性加性效应：一种新型GCK-MODY小鼠模型的研究	Salazar, S.	PDF	N/A	Sex-dependent additive effects of dorzagliatin and incretin on insulin secretion in a novel mouse model of GCK-MODY
预印本与期刊文章：COVID-19研究中的引用影响	Tsunoda, H.	PDF	N/A	Preprints vs. Journal Articles: Citation Impact in COVID-19 Research
能够选择性靶向RAS驱动型癌症的合成基因电路	Senn, G. V.	PDF	N/A	Synthetic gene circuits that selectively target RAS-driven cancers
多组学分析揭示了来自海鞘Botryllus schlosseri的微生物衍生代谢物在金属相互作用中的重要作用	Matus, D. G. G.	PDF	N/A	Multi-omics Analysis Reveals Important Role for Microbial-derived Metabolites from Botryllus schlosseri in Metal Interactions
植物高度动态杂种优势的代谢途径在水稻中是稳健的生物标志物。	Dan, Z.	PDF	N/A	The metabolic pathways underlying dynamic heterosis for plant height are robust biomarkers in rice
夜行性土豚（Orycteropus afer，管齿目）的眼部特征与视网膜感光细胞	Peichl, L.	PDF	N/A	Eye features and retinal photoreceptors of the nocturnal aardvark (Orycteropus afer, Tubulidentata)
老化大脑的自由水消除径向测量法	Chang, K. H.	PDF	N/A	Free water elimination tractometry for aging brains
超越字母：最优传输作为亚字母正字法处理的模型	Taylor, J. E.	PDF	N/A	Beyond Letters: Optimal Transport as a Model for Sub-Letter Orthographic Processing
皮层内微刺激导致脑血流与神经活动空间错配	Yonza, A. K. I.	PDF	N/A	Spatially mismatched cerebral blood flow and neuronal activity by intracortical microstimulation
个性化fMRI引导rTMS目标的分水岭算法图形用户界面	Feng, Z.-j.	PDF	N/A	A Watershed Algorithm GUI for Personalized fMRI-guided rTMS Target
系统性自身免疫病中常见罕见和新奇的RELA变异	Downes, M. B.	PDF	N/A	Rare and novel RELA variants are common in systemic autoimmunity
在两匹患有急性呼吸综合征的马的淋巴结和肺组织中发现的昆虫特异性阿尔法介体病毒1（Mesoniviridae科）	Jurisic, L.	PDF	N/A	Insect-specific Alphamesonivirus-1 (Mesoniviridae) in lymph node and lung tissues from two horses with acute respiratory syndrome
蛇纹岩的微生物生态学	Colman, D. R.	PDF	N/A	The Microbial Ecology of Serpentinites
圈养繁殖的墨西哥钝口螈在恢复和人工湿地中的运动生态学：两栖动物再引入和迁徙的保育启示	Ramos, A. G.	PDF	N/A	Movement ecology of captive-bred axolotls in restored and artificial wetlands: conservation insights for amphibian reintroductions and translocations
野生动物贸易的过度监管	Challender, D.	PDF	N/A	Disproportionate regulation of wildlife trade
大规模遥感数据显示，德国的树木死亡率似乎高于之前的预期。	Schiefer, F.	PDF	N/A	Large-scale remote sensing reveals that tree mortality in Germany appears to be greater than previously expected
与火灾后的模式相比，在皆伐和抢救性采伐后的土壤群落具有不同的早期演替动态。	Porter, T. M.	PDF	N/A	Soil communities following clearcut and salvage harvest have different early successional dynamics compared with post-wildfire patterns
多源摄影证据评估亚洲象的走廊使用情况、作物侵袭行为及身体伤害	NR, A.	PDF	N/A	Multi-source photographic evidence to assess corridor use, crop-raiding behaviour, and body injuries in Asian elephants
大量开花和花期不同步是西高止山脉一个季节性草本植物群落的特征。	Shrotri, S.	PDF	N/A	Mass flowering and flowering asynchrony characterise a seasonal herbaceous community in the Western Ghats
通过扩展的DEST 2.0基因组资源，在结构化种群的D. melanogaster中全球适应的足迹	Nunez, J. C. B.	PDF	N/A	Footprints of worldwide adaptation in structured populations of D. melanogaster through the expanded DEST 2.0 genomic resource
被子植物中葡萄性别决定区域的演化历史及葡萄科中雌雄异株的出现	Massonnet, M.	PDF	N/A	Evolutionary history of the grape sex-determining region in angiosperms and emergence of dioecy in Vitaceae
mRNP组成的各种改变会引发有害R-loop的增加	Merida-Cerro, J. A.	PDF	N/A	Different alterations in mRNP composition trigger an increase in harmful R-loops
大鼠单核多器官染色质可及性图谱	Li, R.	PDF	N/A	Single-nucleus multiple-organ chromatin accessibility mapping in the rat
蜜蜂嗅觉行为的机器学习在野外自由飞行的蜜蜂中识别出排斥性气味物质	Kowalewski, J.	PDF	N/A	Machine learning of honey bee olfactory behavior identifies repellent odorants in free flying bees in the field
人类行走的能量消耗作为不平坦地形幅度的函数	Hosseini-Yazdi, S.-S.	PDF	N/A	The energetic cost of human walking as a function of uneven terrain amplitude
可编程蛋白质降解剂能够在体外和体内选择性敲低致病性β-连环蛋白亚群	Ye, T.	PDF	N/A	Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo
评估深度学习生成的三维分子的构象有效性和合理性	Fan, F.	PDF	N/A	Assessing Conformation Validity and Rationality of Deep Learning-Generated 3D Molecules
利用进化尺度建模的深度学习方法发现针对肺炎克雷伯菌的抗生素耐药药物	Jin, L.	PDF	N/A	Deep Learning with Evolutionary Scale Modeling to discover Antibiotic-Resistance Drug against Klebsiella Pneumoniae
Diverse-Seq：一种用于无对齐选择和聚类生物序列的应用程序	Huttley, G. A.	PDF	N/A	diverse-seq: an application for alignment-free selecting and clustering biological sequences
通过局部治疗克服乳腺癌耐药性的多靶点天然配体及高效siRNA设计的计算机发现	Hashemi, S. M. J.	PDF	N/A	In Silico Discovery of Multi-Target Natural Ligands and Efficient siRNA Design for Overcoming Drug Resistance in Breast Cancer via Local Therapy
ROSIE：从组织病理学图像生成多重免疫荧光染色的人工智能技术	Wu, E.	PDF	N/A	ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images
CYP2E1对肾脏的性别依赖性影响及4MP对顺铂诱导肾毒性的保护潜力	Akakpo, J. Y.	PDF	N/A	Sex-dependent effects of CYP2E1 on the kidney and the protective potential of 4MP against cisplatin-induced nephrotoxicity
根木质部面积通过土壤质地依赖的方式影响珍珠粟的耐旱性和蒸腾作用	Affortit, P.	PDF	N/A	Root metaxylem area influences drought tolerance and transpiration in pearl millet in a soil texture dependent manner
聚苯乙烯纳米塑料通过催化TDP43的过度磷酸化促进神经退行性变。	Winanto, W.	PDF	N/A	Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation
基底节颤抖症中丘脑、小脑和运动皮层之间的振荡耦合	Steina, A.	PDF	N/A	Oscillatory coupling between thalamus, cerebellum and motor cortex in essential tremor
以少胜多：基于模拟的推断使得在极短的采集时间内也能获得准确的扩散加权磁共振成像	Eggl, M. F.	PDF	N/A	More with less: Simulation-based inference enables accurate diffusion-weighted MRI with minimal acquisition time
持续的感觉运动转换增强了猕猴运动皮层神经动力学对扰动的鲁棒性	Cui, H.	PDF	N/A	Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex
人类对基因减毒疟原虫的相关体液和细胞免疫	Colstrup, E.	PDF	N/A	Correlative humoral and cellular immunity to genetically attenuated malaria parasites in humans
一种调节因子在莫拉氏菌科中同时调控DNA损伤应答与抗噬菌体防御网络	Song, S.	PDF	N/A	A regulator controls both DNA damage response and anti-phage defense networks in Moraxellaceae
卵母细胞中CDK12的缺失导致女性不孕	Jansova, D.	PDF	N/A	Absence of CDK12 in oocyte leads to female infertility
SARS-CoV-2 BA.2.86变异株及其亚系在刺突蛋白中对赖氨酸的偏好增加，而对精氨酸的偏好减少。	Bozic, A.	PDF	N/A	Increased preference for lysine over arginine in spike proteins of SARS-CoV-2 BA.2.86 variant and its sublineages
Src抑制对人类膀胱癌临床前模型中转移决定因素的异质性效应	Aragaki, K.	PDF	N/A	Heterogeneous Effects of Src Inhibition on Determinants of Metastasis in Preclinical Models of Human Bladder Cancer
ELOVL6作为治疗靶点：破坏c-MYC驱动的脂质代谢以增强胰腺癌化疗	Garcia Garcia, A.	PDF	N/A	ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
活细胞磁性显微操作回收内体揭示其对促进侵袭性迁移的肌动蛋白基突起的直接影响	Gemperle, J.	PDF	N/A	Live-cell magnetic micromanipulation of recycling endosomes reveals their direct effect on actin-based protrusions to promote invasive migration
心脏修复中纤维化生态位的时空动力学	Grün, D.	PDF	N/A	Spatio-temporal dynamics of the fibrotic niche in cardiac repair
家蚕茧的抗刺穿性能	Rehman, A. U.	PDF	N/A	The stab resistance of Bombyx mori silk cocoons
新发现的脊椎动物早期抗病毒感染中IgM的保守作用	Kong, W.	PDF	N/A	Newly discovered and conserved role of IgM against viral infection in an early vertebrate
胆固醇代谢与结核分枝杆菌内部的钾离子稳态之间存在内在关联。	Chen, Y.	PDF	N/A	Cholesterol metabolism and intrabacterial potassium homeostasis are intrinsically related in Mycobacterium tuberculosis
用于研究COVID感染后遗症的适应小鼠的SARS-CoV-2模型	Zhao, Z.	PDF	N/A	A Mouse-adapted SARS-CoV-2 Model for Investigating Post-acute Sequelae of COVID infection
模拟近海油田环境：双厌氧生物膜反应器对微生物诱导腐蚀的见解	Jones, L. M.	PDF	N/A	Simulating Offshore Oilfield Conditions: Insights into Microbiologically Influenced Corrosion from a Dual Anaerobic Biofilm Reactor
在细胞间传播过程中，志贺氏菌（Shigella flexneri）需要一个具有易位能力的孔道来逃逸双层膜液泡。	Raab, J. E.	PDF	N/A	A translocation-competent pore is required for Shigella flexneri to escape from the double membrane vacuole during intercellular spread
微管结合诱导了动力蛋白-1中一种类似于Mg-free的ADP预释放构象，这种构象不受其自抑制尾的影响。	Atherton, J.	PDF	N/A	Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail
食品级植物抗氧化剂配方抑制肌红蛋白氧化	Vergara-Stange, V.	PDF	N/A	Inhibition of Myoglobin Oxidation by Food Grade Botanical Antioxidant Formulations
UniOP：一种利用基因间距离对高通量原核生物（元）基因组数据进行通用操纵子预测的方法	Su, H.	PDF	N/A	UniOP: a universal operon prediction for high-throughput prokaryotic (meta-)genomic data using intergenic distance
AlphaBind，一种特定领域的模型，用于预测和优化抗体-抗原结合亲和力	Agarwal, A. A.	PDF	N/A	AlphaBind, a Domain-Specific Model to Predict and Optimize Antibody-Antigen Binding Affinity
使用条件最优传输在单细胞水平建模CAR响应	Driessen, A.	PDF	N/A	Modeling CAR Response at the Single-Cell Level Using Conditional Optimal Transport
从人诱导多能干细胞生成形态不同的星形胶质细胞亚型揭示了胶质形态、功能和反应性之间的联系	O'Toole, K.	PDF	N/A	Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity
极光激酶A通过调节内源性S-腺苷甲硫氨酸代谢促进训练免疫	Li, M.	PDF	N/A	Aurora kinase A promotes trained immunity via regulation of endogenous S-adenosylmethionine metabolism
单分子成像技术在T细胞转录动力学、RNA定位及命运研究中的应用	Lattanzio, M. V.	PDF	N/A	Single molecule imaging of transcription dynamics, RNA localization and fate in T cells
比较基因组学揭示粘细菌碳水化合物降解潜力及其生态影响。	Saraf, N.	PDF	N/A	Comparative genomic insight into the myxobacterial carbohydrate-degrading potential and their ecological impact.
抗病毒抗性进化揭示了基孔肯雅病毒包膜糖蛋白之间短暂的跨域功能相互作用	Battini, L.	PDF	N/A	Evolution of antiviral resistance captures a transient interdomain functional interaction between chikungunya virus envelope glycoproteins
在半高通量分析中评估青蒿素治疗后恶性疟原虫的生长、抗性和恢复情况	Sievert, M. A.	PDF	N/A	Measuring Growth, Resistance and Recovery after Artemisinin Treatment of Plasmodium falciparum in a semi-high-throughput Assay
乙醇胺诱导的微隔室组装是具核梭杆菌毒力所必需的	Franklin, D.	PDF	N/A	Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence
解析关键分类单元：门多塔湖微生物网络内的相互作用及环境动态	Yang, Q.	PDF	N/A	Unraveling Keystone Taxa: Interactions Within Microbial Networks and Environmental Dynamics in Lake Mendota
NLRP1 被棕榈酸激活，并在人类代谢功能障碍相关性脂肪性肝炎中被诱导。	Pinilla, M.	PDF	N/A	NLRP1 is activated by palmitic acid and induced in human metabolic dysfunction-associated steatohepatitis
在卵子发生和早期胚胎发生过程中对bicoid mRNA的调控影响蛋白质梯度的形成。	Athilingam, T.	PDF	N/A	Regulation of bicoid mRNA throughout oogenesis and early embryogenesis impacts protein gradient formation
毛里求斯果蝇中交叉分布的模式需要重新思考着丝粒对交叉的影响	Hawley, R. S.	PDF	N/A	Patterns of crossover distribution in Drosophila mauritiana necessitate a re-thinking of the centromere effect on crossing over
U1 snRNP特异性蛋白U1C在snRNP生物发生中充当运动神经元生存（SMN）复合体的守门员	Ngu, D. M.	PDF	N/A	U1 snRNP-Specific U1C Acts as the Gatekeeper of the Survival of Motor Neurons (SMN) Complex in snRNP Biogenesis
通过定制的CRISPR-Cas9碱基编辑器治疗体内严重的血管疾病	Alves, C. R. R.	PDF	N/A	In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor
负链RNA病毒中的转录梯度提示了一种共同的RNA转录机制	King, C. R.	PDF	N/A	The Transcriptional Gradient in Negative-Strand RNA Viruses Suggests a Common RNA Transcription Mechanism
升高的I型干扰素信号定义了ARF和p53突变肿瘤细胞的增殖优势	Mabry, A.	PDF	N/A	Elevated type I interferon signaling defines the proliferative advantage of ARF and p53 mutant tumor cells
Elovl1抑制减少了肾上腺脑白质营养不良小鼠模型中的极长链脂肪酸。	Huang, J.	PDF	N/A	Elovl1 inhibition reduced very long chain fatty acids in a mouse model of adrenoleukodystrophy
MdMPK6/02G介导的MdWRKY70L磷酸化调控活性氧合成以调节苹果果实衰老	Wang, H.	PDF	N/A	Phosphorylation of MdWRKY70L by MdMPK6/02G mediates reactive oxygen synthesis to regulate apple fruit senescence
自然语言提示指导新型功能性蛋白质序列的设计	Praljak, N.	PDF	N/A	Natural Language Prompts Guide the Design of Novel Functional Protein Sequences
固定石蜡包埋活检的单细胞空间转录组学揭示了与结肠炎相关的细胞网络	Mennillo, E.	PDF	N/A	Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks
艰难梭菌的抗菌药物敏感性测试：一项针对三种不同培养基和三种治疗性抗菌药物的双中心研究	Freeman, J.	PDF	N/A	Antimicrobial susceptibility testing of Clostridioides difficile: a dual-site study of three different media and three therapeutic antimicrobials
构象变化、过剩面积及Piezo蛋白-膜纳米穹顶的弹性：来自粗粒化和原子模拟的研究	Dixit, S.	PDF	N/A	Conformational changes, excess area, and elasticity of the Piezo protein-membrane nanodome from coarse-grained and atomistic simulations
共享住宅庭院中的生物多样性潜力	Livne, H.	PDF	N/A	Potential for Biodiversity in Shared Residential Yards
适应性蛋白质协同进化保持端粒完整性	Futeran, H.	PDF	N/A	Adaptive protein coevolution preserves telomere integrity
全面评估AlphaFold-Multimer、AlphaFold3和ColabFold在预测蛋白质-肽复合物结构中的表现及评分函数	Manshour, N.	PDF	N/A	Comprehensive Evaluation of AlphaFold-Multimer, AlphaFold3 and ColabFold, and Scoring Functions in Predicting Protein-Peptide Complex Structures
在慢性病毒感染小鼠期间，凝血酶原可预防致命的T细胞依赖性贫血	Cantrell, R.	PDF	N/A	Prothrombin prevents fatal T cell-dependent anemia during chronic virus infection of mice
饥饿通过抑制纹状体尾部多巴胺信号来调节探索行为	Kamath, T.	PDF	N/A	Hunger modulates exploration through suppression of dopamine signaling in the tail of striatum
扩展杏仁核促肾上腺皮质激素释放激素神经元调控草原田鼠（Microtus ochrogaster）在社会挫败后配对结合形成的性别二态性变化	Tickerhoof, M. C.	PDF	N/A	Extended amygdala corticotropin-releasing hormone neurons regulate sexually dimorphic changes in pair bond formation following social defeat in prairie voles (Microtus ochrogaster)
呼吸网络中的非对称神经调制有助于节律和模式的生成。	Dhingra, R. R.	PDF	N/A	Asymmetric neuromodulation in the respiratory network contributes to rhythm and pattern generation
来自CDKL5缺陷症患者来源的皮质兴奋性神经元在早期表现出过度兴奋性，而这种过度兴奋性在由Neurogenin2诱导的神经元中未被发现。	Glass, M. R.	PDF	N/A	Excitatory Cortical Neurons from CDKL5 Deficiency Disorder Patient-Derived Organoids Show Early Hyperexcitability Not Identified in Neurogenin2 Induced Neurons
对性别偏向选择反应的表达分歧	Grieshop, K.	PDF	N/A	Expression divergence in response to sex-biased selection
中性粒细胞胞外陷阱促进肿瘤对蒽环类药物的化学耐药性	Lin, C.	PDF	N/A	Neutrophil extracellular traps promote tumor chemoresistance to anthracyclines
线粒体相关内质网膜对胆固醇稳态的贡献	Montesinos, J.	PDF	N/A	The contribution of mitochondria-associated ER membranes to cholesterol homeostasis
# BioRxiv 2024-11-10 Papers

标题	作者	PDF链接	代码仓库	Title
地方志揭示了中国东部顶级捕食者和中型捕食者历史分布变化的对比模式	Hu, K.	PDF	N/A	Local Gazetteers Reveal Contrasting Patterns of Historical Distribution Changes between Apex Predators and Mesopredators in Eastern China
人乳头瘤病毒的非网格蛋白依赖性内吞作用由肌动蛋白成核促进因子WASH辅助完成。	Brinkert, P.	PDF	N/A	Clathrin-independent endocytosis of Human Papillomaviruses is facilitated by actin nucleation promoting factor WASH
排列匹配测试：尽管存在非平稳性和有限重复，仍能检测时间序列之间显著相关性的方法	Yuan, A. E.	PDF	N/A	Permute-match tests: Detecting significant correlations between time series despite nonstationarity and limited replicates
基于纳米孔测序的多重PCR检测四种罗非鱼病原体的序列分析	Delamare-Deboutteville, J.	PDF	N/A	Multiplex PCR with Nanopore Sequencing for Sequence-Based Detection of Four Tilapia Pathogens
马寄生虫中数量最多的Cylicocyclus nassatus对吡喹酮抗性的时空多样性和遗传结构	Salle, G.	PDF	N/A	Spatio-temporal diversity and genetic architecture of pyrantel resistance in Cylicocyclus nassatus, the most abundant horse parasite
系统分析无义变异揭示了肽释放速率作为无义介导的mRNA衰变的新型修饰因子	Kolakada, D.	PDF	N/A	Systematic analysis of nonsense variants uncovers peptide release rate as a novel modifier of nonsense-mediated mRNA decay
在霍乱弧菌中，MatP局部富集延迟了分离，与四聚体形成和隔膜锚定无关。	Espinosa, E.	PDF	N/A	MatP local enrichment delays segregation independently of tetramer formation and septal anchoring in Vibrio cholerae
Celldetective：一种利用人工智能增强的图像分析工具，用于揭示动态细胞相互作用	Torro, R.	PDF	N/A	Celldetective: an AI-enhanced image analysis toolfor unraveling dynamic cell interactions
贝叶斯选择松弛时钟模型：区分独立和自相关速率	Panchaksaram, M.	PDF	N/A	Bayesian Selection of Relaxed-clock Models:Distinguishing Between Independent and Autocorrelated Rates
棉铃虫通过储存和释放挥发性物质，在野生棉花（Gossypium hirsutum）种群中诱导出不同的萜烯化学型。	Mamin, M.	PDF	N/A	Induction by caterpillars of stored and emitted volatiles in terpene chemotypes from populations of wild cotton (Gossypium hirsutum)
牺牲适应性以换取功能性：视网膜Müller细胞的象牙塔	Zhang, T.	PDF	N/A	Sacrificing Adaptability for Functionality: The Ivory Tower of Macular Muller Cells
预测高度灵活、变构、多结构域蛋白质中的结合事件	Basciu, A.	PDF	N/A	Predicting binding events in very flexible, allosteric, multi-domain proteins
基于能量的葡萄糖运输的键图模型，涉及SLC转运蛋白	Hunter, P. J.	PDF	N/A	Energy-based bond graph models of glucose transport with SLC transporters
小鼠防御素基因座中的遗传变异调节血糖稳态	Masson, S. W. W.	PDF	N/A	Genetic variance in the murine defensin locus modulates glucose homeostasis
产前高膳食钙补充对奶羊和奶山羊钙和骨稳态及其后代生长反应的影响	Brugger, D.	PDF	N/A	High dietary calcium supplementation ante partum and effects on calcium and bone homeostasis of dairy sheep and goats and growth response of their offspring
发现了一种单亚基寡糖基转移酶，使大肠杆菌中全长IgG抗体的糖基化成为可能	Sotomayor, B.	PDF	N/A	Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in Escherichia coli
CA3中的选择性抑制：通过异源突触可塑性实现稳定模式完成的机制	Kim, G.	PDF	N/A	Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity
基准测试用于DNA结合蛋白识别的最新计算工具	Luo, X.	PDF	N/A	Benchmarking Recent Computational Tools for DNA-binding Protein Identification
Robinow综合征DVL1变异体在果蝇疾病模型中破坏形态发生和附肢形成	Akarsu, G.	PDF	N/A	Robinow Syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model
生物工程改造一种常见的益生菌以利用结肠炎症，在炎症性肠病的转化模型中促进了可靠的疗效	Verdugo Meza, A.	PDF	N/A	Bio-engineering a common probiotic to exploit colonic inflammation promotes reliable efficacy in translational models of colitis
体内功能分析与人类Glp1r A316T变异体的结构表征	El Eid, L.	PDF	N/A	In vivo functional profiling and structural characterisation of the human Glp1r A316T variant
通过空间蛋白质组学揭示初级纤毛的内在多样性	Hansen, J. N.	PDF	N/A	Intrinsic Diversity In Primary Cilia Revealed Through Spatial Proteomics
全面的蛋白酶特异性分析	Zhu, B.	PDF	N/A	Comprehensive protease specificity profiling
一种共识变异-功能评分，用于为疾病功能性地优先考虑变异	Fabiha, T.	PDF	N/A	A consensus variant-to-function score to functionally prioritize variants for disease
光遗传学杏仁核中央核刺激在雄性大鼠中具有高度强化作用，并且显著优于芬太尼自我给药，但在雌性大鼠中则不然。	Chaloux-Pinette, E.	PDF	N/A	Optogenetic Central Amygdala Stimulation is Highly Reinforcing and Strongly Outcompetes Fentanyl Self-Administration in Male, but not Female, Rats
将脑信号建模为马尔可夫过程有助于解释其结构与功能之间的关系。	Razban, R.	PDF	N/A	Modeling brain signaling as Markovian helps explain its structure-function relationship
使用基于连接组预测建模方法，直接比较静息态和任务态脑电图功能连接模式对工作记忆表现的预测能力。	Pashkov, A. A.	PDF	N/A	Direct comparison of EEG resting state and task functional connectivity patterns for predicting working memory performance using connectome-based predictive modeling
时间队列编号、神经元组成和连接性沿果蝇幼虫体轴有所变化。	Vasudevan, D.	PDF	N/A	Temporal cohort number, neural composition, and connectivity vary along the Drosophila larval body axis
TiFM2.0 - 在活体胚胎中实现多功能的机械测量与驱动	Hernandez-Rodriguez, A. R.	PDF	N/A	TiFM2.0 - Versatile mechanical measurement and actuation in live embryos
单细胞与空间多组学揭示干扰素信号在肛周瘘管性克罗恩病发病机制中的作用	Cao, S.	PDF	N/A	Single-Cell and Spatial Multi-omics Reveal Interferon Signaling in the Pathogenesis of Perianal Fistulizing Crohn's Disease
Grin2a功能低下破坏了海马网络振荡和E/I平衡，进而导致认知缺陷。	Hosseini, H. S.	PDF	N/A	Grin2a Hypofunction Disrupts Hippocampal Network Oscillations and E/I Balance Contributing to Cognitive Deficits
利用针对阿尔茨海默病治疗的校正剂重新编程神经元的分泌和代谢机制	Cho, W. J.	PDF	N/A	Reprogramming the neuronal secretory and metabolic machinery using correctors for Alzheimer therapy
中国阴道微生物群的地理特异性多样化	Yang, H.	PDF	N/A	Geographic-specific Diversification of Vaginal Microbiota in China
药品的环境影响：近期关于水生浓度及可预测效应的证据映射综述	Renda, F.	PDF	N/A	The environmental impact of pharmaceuticals: an evidence-mapping review of recent data on aquatic concentrations and predictable effects
东南亚厄尔尼诺驱动的干旱、火灾和烟雾对非人类灵长类动物影响的综合评述	Erb, W. M.	PDF	N/A	A Systematic Review of the Impacts of El Nino-Driven Drought, Fire, and Smoke on Non-Human Primates in Southeast Asia
Tidyplots 使生命科学家能够通过简单的代码实现数据可视化。	Engler, J. B.	PDF	N/A	Tidyplots empowers life scientists with easy code-based data visualization
三阴性乳腺癌患者远处转移的风险因素、预后因素及诺模图：一项基于人群的研究	Guo, H.	PDF	N/A	Risk factors, prognostic factors, and nomograms for distant metastasis in patients with triple-negative breast cancer: a population-based study
在直肠癌患者中，上皮间质转化（Epithelial Mesenchymal Transition, EMT）的形态分子特征与临床预后相关。	Gwerder, M.	PDF	N/A	Morpho-molecular features of Epithelial Mesenchymal Transition associate with clinical outcome in patients with rectal cancer
卒中和运动恢复与周期性和非周期性皮层活动的区域性和年龄特异性变化有关	Albertson, A. J.	PDF	N/A	Stroke and Motor Recovery are Associated with Regional and Age-Specific Changes in Periodic and Aperiodic Cortical Activity
生成用于SARS-CoV-2复制子传递颗粒感染的生物安全小鼠模型	Li, Y.	PDF	N/A	Generation of a biosafety mouse model infection for SARS-CoV-2 replicon delivery particles
西北大西洋中B族维生素和钴胺素共同限制的季节性模式	Bannon, C. C.	PDF	N/A	Seasonal patterns in b-vitamins and cobalamin co-limitation in the Northwest Atlantic
利用CRISPR-Cas9技术对硅藻浮游生物中单细胞微生物群进行分析，以鉴定稀有细菌类群	Giesler, J. K.	PDF	N/A	A CRISPR-Cas9 assisted analysis of single-cell microbiomes for identifying rare bacterial taxa in phycospheres of diatoms
在HSV-1感染的细胞中，pUL16和pUL21的同时缺失会导致细胞质包膜形成的中断。	Roddy, K.	PDF	N/A	The loss of both pUL16 and pUL21 in HSV-1 infected cells abolishes cytoplasmic envelopment.
Pemivibart对SARS-CoV-2 JN.1亚系的灭活作用及其病毒逃逸	Yao, T.	PDF	N/A	Neutralizing Activity and Viral Escape of Pemivibart by SARS-CoV-2 JN.1 sublineages
从随机序列中模拟球状蛋白质折叠的进化过程	Sahakyan, H.	PDF	N/A	In silico evolution of globular protein folds from random sequences
在濒临灭绝的鹦鹉中，基因组范围和免疫基因多样性的暂时丧失	Silver, L. W.	PDF	N/A	Temporal loss of genome-wide and immunogenetic diversity in a near-extinct parrot
提高了有序双模板中继cDNA文库制备在RNA测序中的精确度、灵敏度和适应性	Ferguson, L.	PDF	N/A	Improved precision, sensitivity, and adaptability of Ordered Two-Template Relay cDNA library preparation for RNA sequencing
Pfs230 域 12 是一种强效的疟疾传播阻断疫苗候选物。	Inklaar, M. R.	PDF	N/A	Pfs230 Domain 12 is a potent malaria transmission-blocking vaccine candidate
复苏促进因子（Rpf）终止了多种土壤细菌的休眠状态。	Lennon, J. T.	PDF	N/A	Resuscitation-promoting factor (Rpf) terminates dormancy among diverse soil bacteria
通过福尔马林反应降解非生物合成四碳糖的细菌的分离	Kawasaki, K.	PDF	N/A	Isolation of bacteria that catabolize abiotically synthesized tetroses via the formose reaction
利用生成语言模型从头设计磷酸丙糖异构酶	Romero-Romero, S.	PDF	N/A	De novo design of triosephosphate isomerases using generative language models
双酶抑制策略治疗2型糖尿病：以黄酮-阿卡波糖组合靶向LDH-A和α-淀粉酶	Gupta, S.	PDF	N/A	Dual Enzyme Inhibition Strategy for Type 2 Diabetes: Targeting LDH-A and α-Amylase with Flavonoid-Acarbose Combinations
AlphaFold-Metainference：无序蛋白质结构集合的预测	Brotzakis, Z. F.	PDF	N/A	AlphaFold-Metainference: Prediction of Structural Ensembles of Disordered Proteins
海洋光合作用直接受到噬藻体NblA蛋白的影响。	Beja, O.	PDF	N/A	Oceanic photosynthesis is directly affected by cyanophage NblA proteins
卟啉单胞菌的基因组多样性：卟啉单胞菌猫属共生在肺部的证据	VELO-SUAREZ, L.	PDF	N/A	Genomic Diversity in Porphyromonas: Evidence of Porphyromonas catoniae Commensality in Lungs
ComFB是一种新近广泛分布的环二核苷酸受体蛋白家族	Samir, S.	PDF	N/A	ComFB, a new widespread family of c-di-NMP receptor proteins
在铁充足、铁缺乏和铁替代状态下，血浆和心肌中铁状态生物标志物的不一致性。	Tomkova, K.	PDF	N/A	Discordance between biomarkers of iron status in plasma and myocardium across iron replete, iron deficiency, and iron replacement states.
氟喹诺酮类药物依诺沙星的抗HIV-1作用及对前病毒hsa-miR-132加工的调控	Imig, J.	PDF	N/A	Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-viral hsa-miR-132 Processing
翻译校对过程中产生的同型半胱氨酸硫内酯是一种内源性配体，通过受体SdiA进行细胞间信号传导。	Leiva, L. E.	PDF	N/A	Homocysteine thiolactone from translation proofreading is an endogenous ligand for cell-cell signaling by the receptor SdiA
对非洲乳菇属（Russula）的拉丁根亚属（radicans）及其近缘类群在异叶亚属（Heterophyllidiae）中的修订，提供了一个近期分化且具有广泛表型可塑性的进化枝的实例。	Buyck, B.	PDF	N/A	A revision of the African Russula radicans and allies in subgen. Heterophyllidiae provides an example of a clade that exhibits recent diversification and extensive phenotypic plasticity.
AI辅助的本地蛋白质组学：描绘核糖体蛋白组装前后的构象	Zhang, W.	PDF	N/A	AI Assisted Native Proteomics: Delineating Ribosomal Protein Conformations Pre- and Post-Assembly
鉴定出一群在骨关节炎大鼠模型中具有增强治疗效果的滑膜间充质干细胞亚群	Al_Jezani, N.	PDF	N/A	Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of Osteoarthritis
通过REDCAT实现单细胞类型特异性代谢活性的全光多模态映射	Shi, L.	PDF	N/A	All-Optical Multimodal Mapping of Single Cell Type-Specific Metabolic Activities via REDCAT
烃类化合物对乳腺癌肿瘤性和非肿瘤性细胞存活及抗氧化系统的影响。	Mardirosian, M. N.	PDF	N/A	Hydrocarbon effects on cell survival and antioxidant system of breast tumorigenic and non-tumorigenic cells.
细胞质长链非编码RNA（lncRNAs）启动信号通路，以定义亚稳态动力学并决定表型输出。	PORTAL, M. M.	PDF	N/A	Cytoplasmic lncRNAs nucleate signalling pathways to define metastable state dynamics and determine phenotypic output
无标记显微镜图像中细胞环境依赖的计算机模拟细胞器定位	Elmalam, N.	PDF	N/A	Cell-context dependent in silico organelle localization in label-free microscopy images
M1连接的泛素化通过LUBAC调控AMPK活性及对能量应激的响应	Elbaek, C. R.	PDF	N/A	M1-linked Ubiquitination by LUBAC Regulates AMPK Activity and the Response to Energetic Stress
小GTPase Rap1与哺乳动物肿瘤抑制蛋白同源物KrsB之间的负反馈回路调节了Dictyostelium中的细胞-基质粘附。	Artemenko, Y.	PDF	N/A	A negative feedback loop between small GTPase Rap1 and mammalian tumor suppressor homolog KrsB regulates cell-substrate adhesion in Dictyostelium
TXNL1结合的蛋白酶体结构	Gao, J.	PDF	N/A	Structure of the TXNL1-bound proteasome
减少功能缺陷的造血干细胞可缓解老年小鼠的衰老相关表型	Zhang, Y.	PDF	N/A	Reducing functionally defective HSCs alleviates aging-related phenotypes in old mice
# BioRxiv 2024-11-09 Papers

标题	作者	PDF链接	代码仓库	Title
序列和化学特异性定义了固有无序区域的功能景观	Langstein-Skora, I.	PDF	N/A	Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions
一种校正转录组关联研究中预测表达不确定性的方法	Majumdar, A.	PDF	N/A	A method to adjust for the uncertainty of predicted expression in transcriptome-wide association study
DnaB-复制解旋酶-噬菌体{lambda}P装载复合物的自抑制构象	Brown, D.	PDF	N/A	An Autoinhibited Conformation of the DnaB-Replicative Helicase - phage {lambda}P Loader Complex
探究数学学习困难儿童的前额叶-顶叶网络及激活情况：不同缺陷特征的案例研究	Wang, F.	PDF	N/A	Investigating Frontoparietal Networks and Activation in Children with Mathematics Learning Difficulties: Cases with Different Deficit Profiles
小脑浦肯野细胞控制斑马鱼（Danio rerio）幼体的姿势	Auer, F.	PDF	N/A	Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)
种群大小与生殖寿命相互作用，共同塑造了种系突变率。	Zhu, L.	PDF	N/A	Population size interacts with reproductive longevity to shape the germline mutation rate
未配对和异质性临床流式细胞术数据的整合	Phuycharoen, M.	PDF	N/A	Integration of Unpaired and Heterogeneous Clinical Flow Cytometry Data
组合预训练提高了计算效率，并在复杂任务上与动物行为相匹配。	Hocker, D. L.	PDF	N/A	Compositional pretraining improves computational efficiency and matches animal behavior on complex tasks
通过随机连接的前馈网络中的树突计算来区分神经集合模式	Somashekar, B. P.	PDF	N/A	Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks
HistoGWAS：一种用于组织学队列中组织表型自动化遗传分析的AI驱动框架	Chaudhary, S.	PDF	N/A	HistoGWAS: An AI-enabled Framework for Automated Genetic Analysis of Tissue Phenotypes in Histology Cohorts
新热带生物多样性指标的基因组学：两种蝴蝶辐射具有猖獗的染色体重排和杂交现象	van der Heijden, E. S.	PDF	N/A	Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation
质心工作组件可能为任何行走条件下的首选行走速度提供估计	Hosseini-Yazdi, S.-S.	PDF	N/A	Center of Mass Work Components May Offer Estimates for Preferred Walking Speeds for Any Walking Conditions
线粒体直接重复序列减少作为增强人类长寿的策略：常见重复序列的案例	Shamanskiy, V. A.	PDF	N/A	Mitochondrial direct repeat reduction as a strategy for enhancing human longevity: the case of the common repeat
空间转录组学基因表示框架	Cao, S.	PDF	N/A	A framework for gene representation on spatial transcriptomics
少突胶质细胞利用突触后蛋白来协调在不同神经递质类别轴突上的髓鞘形成。	Carey, N.	PDF	N/A	Oligodendrocytes use post-synaptic proteins to coordinate myelin formation on axons of distinct neurotransmitter classes
解码空间组织结构：一种可扩展的多重成像分析贝叶斯主题模型	Peng, X.	PDF	N/A	Decoding Spatial Tissue Architecture: A Scalable Bayesian Topic Model for Multiplexed Imaging Analysis
MMP21作为一种流体流动输送的形态发生素，在发育过程中赋予生物体左右对称性。	Ott, T.	PDF	N/A	MMP21 behaves as a fluid flow transported morphogen to impart laterality during development
冰川消退后，全浮游栉水母Mnemiopsis的快速物种形成	Ketchum, R. N.	PDF	N/A	Rapid speciation in the holopelagic ctenophore Mnemiopsis following glacial recession
FoldMark：通过水印技术保护蛋白质生成模型	ZHANG, Z.	PDF	N/A	FoldMark: Protecting Protein Generative Models with Watermarking
细胞类型特异性表观基因组编辑在发育中的小鼠皮层中促进中间祖细胞增殖，通过在lncSox1启动子处靶向H3K9乙酰化	Sokpor, G.	PDF	N/A	Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex
使用PANDORA进行MHC II类分子的双向肽构象预测	Rademaker, D. T.	PDF	N/A	Bidirectional Peptide Conformation Prediction for MHC Class II using PANDORA
建模溶瘤痘苗病毒疗法突显了中性粒细胞对肿瘤抑制的影响	Satani, S.	PDF	N/A	Modeling Oncolytic Vaccinia Virus Therapy Highlights Neutrophil Impact on Tumor Suppression
OsMORF蛋白特异性地促进双定位RNA编辑因子OsPGL1与其目标RNA的结合。	Xiao, H.	PDF	N/A	OsMORF protein selectively promotes the dual-localized RNA editing factor OsPGL1 binding to its target RNA
RBPMS和RBPMS2协同作用以保护心脏剪接	Wu, T.	PDF	N/A	RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing
比较留尼汪岛上的白纹伊蚊和致倦库蚊的病毒群落	Francois, S.	PDF	N/A	Contrasted viral communities between Aedes albopictus and Culex quinquefasciatus in La Reunion Island
一种多价适配机制驱动蛋白酶体的核输入	Brunner, H. L.	PDF	N/A	A multivalent adaptor mechanism drives the nuclear import of proteasomes
早发性骨关节炎诱导的COL2A1 p.Arg719Cys人类软骨模型揭示了病理驱动性基质缺陷及内质网蛋白质稳态网络未能识别缺陷型前胶原-II	Yammine, K. M.	PDF	N/A	Human cartilage model of the precocious osteoarthritis-inducing COL2A1 p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II
细胞命运决定与人类GATA1和GATA2谱系决定转录因子中竞争性转录单元的变化相关联。	Anderson, E. M.	PDF	N/A	Cell fate determination is associated with changes in competing transcriptional units in the human GATA1 and GATA2 lineage-determining transcription factors
对具有多个等位基因的位点进行选择的综合表示，允许复杂的基因型适应性形式	Vellnow, N.	PDF	N/A	A comprehensive representation of selection at loci with multiple alleles that allows complex forms of genotypic fitness
小分子奥昔布宁可挽救复杂III缺陷型MPCs的增殖能力	Qu, Y.	PDF	N/A	Small molecule oxybutynin rescues proliferative capacity of complex III-defective MPCs
从嗅球局部场电位推断呼吸节律的挑战	Rafilson, S. E.	PDF	N/A	Challenges in inferring breathing rhythms from olfactory bulb local field potentials
针对促肾上腺皮质激素释放激素受体1型（CRHR1）神经元：验证新型转基因Crhr1-FlpO小鼠的特异性	Hardy, M.	PDF	N/A	Targeting Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Neurons: Validating the Specificity of a Novel Transgenic Crhr1-FlpO Mouse
苍白球外侧部与皮层之间的投射涉及运动和非运动区域。	Ferenczi, E. A.	PDF	N/A	Projections between the globus pallidus externa and cortex span motor and non-motor regions
通过单肽能神经元中频率依赖性递质切换编码对立效价	Kim, D.-I.	PDF	N/A	Encoding opposing valences through frequency-dependent transmitter switching in single peptidergic neurons
双色外显子报告系统揭示了果蝇神经元中电压门控钙离子通道剪接异构体的多样性	Macleod, G. T.	PDF	N/A	Bichromatic exon-reporters reveal voltage-gated Ca2+-channel splice-isoform diversity across Drosophila neurons in vivo
不同的脑电图预处理流程可能导致关于皮层兴奋/抑制比率的结论相互矛盾。	Racz, F. S.	PDF	N/A	Alternative EEG pre-processing pipelines can lead to conflicting conclusions regarding cortical excitation/inhibition ratio
人脑中非周期性神经活动的发展	Cross, Z. R.	PDF	N/A	The development of aperiodic neural activity in the human brain
ERP和神经振荡能否用于区分生态有效运动模型中熟练和非熟练选手的表现？	Winstanley, M.	PDF	N/A	Can ERPs and neural oscillations be used to differentiate skilled and unskilled player performance in an ecologically valid sporting model?
前扣带回神经元显示出与前额叶眼区的亚区特异性相互作用，这一发现是通过结合逆向刺激和静息态成像技术揭示的。	Babapoor-Farrokhran, S.	PDF	N/A	Anterior cingulate neurons display subregion-specific interaction with frontal eye fields as revealed by combined antidromic stimulation and resting state imaging
中央杏仁核谷氨酸对降钙素基因相关肽反应的性别差异	Lorsung, R.	PDF	N/A	Sex differences in central amygdala glutamate responses to calcitonin gene-related peptide
回顾性注意可以触发视觉感知，而不依赖于线索意识或目标报告。	Li, Y.	PDF	N/A	Retrospective Attention Can Trigger Visual Perception Without Dependence on Either Cue Awareness or Target Reporting
经过训练自我给药可卡因或酒精的大鼠中，内侧前额叶皮质神经递质对促进复发和抑制复发的线索的反应	Nedelescu, H.	PDF	N/A	Medial prefrontal cortical neurotransmitters reactive to relapse-promoting and relapse-suppressing cues in rats trained to self-administer cocaine or alcohol
循环事件的神经上下文恢复	Broitman, A. W.	PDF	N/A	Neural Context Reinstatement of Recurring Events
一种整合了偏向竞争和强化学习的视觉注意力神经网络模型	Morgan, J. M.	PDF	N/A	A Neural Network Model of Visual Attention Integrating Biased Competition and Reinforcement Learning
自然猪宿主中呼吸道冠状病毒的发病机制和免疫反应	Sedaghat-Rostami, E.	PDF	N/A	Pathogenesis and immune response to respiratory coronaviruses in their natural porcine host
真菌感染风险条件下常用药物促进白色念珠菌耐药性或抗药性	Obermeier, M.	PDF	N/A	Drugs Commonly Used in Fungal Infection Risk Conditions Promote Drug Tolerance or Resistance in Candida albicans
Drospondin是一种新发现的由神经胶质细胞分泌的糖蛋白，它调控果蝇神经系统的发育和功能。	Rojo-Cortes, F.	PDF	N/A	Drospondin, a novel glial-secreted glycoprotein, controls the development and function of the Drosophila nervous system
进化保守的DNA甲基化的遗传基础、定量性质及功能相关性	Dong, Z.	PDF	N/A	Genetic Basis, Quantitative Nature, and Functional Relevance of Evolutionarily Conserved DNA Methylation
基于纳米孔检测DNA甲基化的工具综合基准测试	Kulkarni, O.	PDF	N/A	Comprehensive benchmarking of tools for nanopore-based detection of DNA methylation
人类26S蛋白酶体中AAA+ ATP酶马达状态的结构景观揭示了TXNL1的构象特异性结合	Martin, A.	PDF	N/A	Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1
DnaB 和 DciA：解旋酶在单链 DNA 上的装载和迁移机制	Gao, N.	PDF	N/A	DnaB and DciA: Mechanisms of Helicase Loading and Translocation on ssDNA
植物γ-谷氨酰肽酶1的晶体结构及其在硫代谢中的双重作用和对氧化应激调控的启示	Sone, K.	PDF	N/A	Crystal structure of plant γ-glutamyl peptidase 1 with dual roles in sulfur metabolism and implications for oxidative stress regulation
语言模型在原核生物中生成顺式调控元件	Xia, Y.	PDF	N/A	Language model generates cis-regulatory elements across prokaryotes
RIBOSS通过结合长读长和短读长转录组及翻译组分析，检测新的翻译事件。	Lim, C. S.	PDF	N/A	RIBOSS detects novel translational events by combining long- and short-read transcriptome and translatome profiling
转化生长因子-β诱导的ERK和SMAD通路的计算建模与分析	Chung, S.	PDF	N/A	Computational Modeling and Analysis of the TGF-β-induced ERK and SMAD Pathways
肠道粪肠球菌的易位通过C型凝集素受体Mincle训练骨髓髓系祖细胞	Robles-Vera, I.	PDF	N/A	Translocation of gut Enterococcus faecalis trains myeloid bone marrow progenitors via the C-type lectin receptor Mincle
表型高通量筛选鉴定出肠道微生物胆碱代谢的调节因子	Woo, A. Y. M.	PDF	N/A	Phenotypic high-throughput screening identifies modulators of gut microbial choline metabolism
原生动物和哺乳动物吞噬细胞对新生隐球菌吞噬反应的共性与差异表明，宿主细胞代谢是其在细胞内生存的目标。	Dragotakes, Q.	PDF	N/A	Commonalities and differences in the Cryptococcus neoformans response to ingestion by protozoal and mammalian phagocytic cells suggests host cell metabolism as a target for intracellular survival
微生物差异能准确识别小鼠中的全球SERT KO表型	Leitman, M.	PDF	N/A	Microbial Differences Accurately Identifies Global SERT KO Phenotype in Mice
评估未充分表征环境中的宏基因组分析：点亮微生物暗物质需要什么？	Nickols, W. A.	PDF	N/A	Evaluating metagenomic analyses for undercharacterized environments: what's needed to light up the microbial dark matter?
从孙德尔本斯采集的银叶树根际中固氮细菌的分离、鉴定与鉴定	Rimi, A. A.	PDF	N/A	Isolation, Characterization, and Identification of Nitrogen Fixing Bacteria from Rhizosphere of Sonneratia apetala Collected from Sundarbans
评估qPCR、dPCR和ddPCR在估算鸣禽血液和精子细胞中线粒体DNA拷贝数的可靠性和准确性	Bagdonaite, L.	PDF	N/A	Assessing reliability and accuracy of qPCR, dPCR and ddPCR for estimating mtDNA copy number in songbird blood and sperm cells
perilipin 5 磷酸化对于禁食状态下肝脏脂质代谢基因的上调并非必需，但在雄性小鼠中对胰岛素受体底物2的表达是必需的。	Bovee, C.	PDF	N/A	Perilipin 5 Phosphorylation is Dispensable for Upregulation of Hepatic Lipid Metabolism Genes upon Fasting but Required for Insulin Receptor Substrate 2 Expression in Male Mice
在多物种背景下解构两种入侵者之间的适应性差异	Freire, T. F. A.	PDF	N/A	Unpacking fitness differences between two invaders in a multispecies context
使用分子条形码进行精确谱系追踪显示了伊维菌素抗性在线虫中的适应性权衡	Stevenson, Z. C.	PDF	N/A	Precise Lineage Tracking Using Molecular Barcodes Demonstrates Fitness Trade-offs for Ivermectin Resistance in Nematodes
一种共识的变异到功能评分，用于为疾病优先考虑功能变异	Fabiha, T.	PDF	N/A	A consensus variant-to-function score to functionally prioritize variants for disease
新型组成型平滑肌细胞特异性Myh11驱动Cre小鼠模型的生成	Dong, K.	PDF	N/A	Generation of a novel constitutive smooth muscle cell-specific Myh11-driven Cre mouse model
TissueMosaic 通过自监督表示学习，实现了空间转录组学数据集的跨样本差异分析。	Kambhampati, S.	PDF	N/A	TissueMosaic enables cross-sample differential analysis of spatial transcriptomics datasets through self-supervised representation learning
苯乙酸在陆地植物中的代谢：新途径与代谢物	Hladik, P.	PDF	N/A	Phenylacetic acid metabolism in land plants: novel pathways and metabolites
使用噬菌体展示技术鉴定靶向蛋白质-蛋白质相互作用共价环状肽抑制剂的鉴定	Wang, S.	PDF	N/A	Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein-Protein Interactions Using Phage Display
类胡萝卜素色素通过光捕获和光循环加速，增强了视紫红质介导的光合作用。	Fujiwara, T.	PDF	N/A	Carotenoid pigments enhance rhodopsin-mediated phototrophy by light-harvesting and photocycle-accelerating
一种细菌细胞壁修复和修饰系统，以抵抗宿主抗菌因子	Burnier, J.	PDF	N/A	A bacterial cell wall repair and modification system to resist host antibacterial factors
GpsB相关调节因子对PBP1a的表征揭示了肺炎链球菌细胞壁重塑复合体的组织结构	Millat, H.	PDF	N/A	Characterization of a GpsB-associated regulator of PBP1a reveals the organization of the cell wall remodeling complex of Streptococcus pneumoniae
分子动力学模拟中蛋白质-脂质相互作用的驻留时间的贝叶斯非参数分析	Sexton, R. C.	PDF	N/A	Bayesian nonparametric analysis of residence times for protein-lipid interactions in Molecular Dynamics simulations
# BioRxiv 2024-11-08 Papers

标题	作者	PDF链接	代码仓库	Title
模型化的网格细胞通过一个灵活的吸引子对齐	Benas, S.	PDF	N/A	Modeled grid cells aligned by a flexible attractor
开发一种定量宏基因组学方法以建立定量限值及其在病毒中的应用	Langenfeld, K.	PDF	N/A	Development of a quantitative metagenomic approach to establish quantitative limits and its application to viruses
MAVISp：基于结构的蛋白质变体效应模块化框架	Arnaudi, M.	PDF	N/A	MAVISp: A Modular Structure-Based Framework for Protein Variant Effects
详细描述了体内参与者和个体环挤压轨迹的影响	Han, R.	PDF	N/A	Detailed in vivo characterization of the players and impact of individual loop extrusion trajectories
锥虫过氧化物酶体输入复合物的结构揭示了构象动力学	Sonani, R. R.	PDF	N/A	Structure of Trypanosoma peroxisomal import complex unveils conformational dynamics
学习微生物组的深度语言模型：大规模未标记微生物组数据的力量	Pope, Q.	PDF	N/A	Learning a deep language model for microbiomes: the power of large scale unlabeled microbiome data
厚组织的三维单细胞转录组成像	Fang, R.	PDF	N/A	Three-dimensional single-cell transcriptome imaging of thick tissues
在高暴露人群中，独特的T细胞特征与减少的衣原体再感染相关	Yount, K. S.	PDF	N/A	Unique T cell signatures associated with reduced Chlamydia trachomatis reinfection in a highly exposed cohort
上皮组织流变学的标度律	Cheikh, M. I.	PDF	N/A	A scaling law for epithelial tissue rheology
TgLaforin，一种葡聚糖磷酸酶，揭示了储存多糖在弓形虫速殖子和缓殖子中的动态作用。	Murphy, R. D.	PDF	N/A	TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites
LRP1 在独立于 NMDA 受体的情况下，通过响应胞外 Tau 触发促炎细胞信号传导。	Azmoon, P.	PDF	N/A	LRP1 Triggers Pro-inflammatory Cell-signaling in Response to Extracellular Tau Independently of the NMDA Receptor
基因和药物对claudin9水平的改变足以诱导功能性和成熟的内毛细胞	Chen, Y.	PDF	N/A	Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells
评估两种近缘的Malurus细尾鹩莺物种中雌性攻击性与雄性表型之间的关系	Jones, J. A.	PDF	N/A	Assessing the relationship between female aggression and male phenotype in two sister Malurus fairywren species
在动作执行和观察过程中，前运动皮质神经元之间的共调制模式逐渐变化，携带动态相似的信号。	Zhao, Z.	PDF	N/A	Progressively shifting patterns of co-modulation among premotor cortex neurons carry dynamically similar signals during action execution and observation
酵母中单细胞eQTL定位揭示了生长与繁殖之间的权衡	Boocock, J.	PDF	N/A	Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
对多巴胺D1和D2受体的药理学调节揭示了非人灵长类动物概率学习中相关的不同神经网络。	Fujimoto, A.	PDF	N/A	Pharmacological modulation of dopamine D1 and D2 receptors reveals distinct neural networks related to probabilistic learning in non-human primates.
一项针对大脑发育的广泛筛查发现，后扣带回皮质在持久记忆的形成中起着关键作用。	Jin, B.	PDF	N/A	A developmental brain-wide screen identifies retrosplenial cortex as a key player in the emergence of persistent memory
多种微生物的还原脱卤作用在深海冷泉的生物地球化学循环中起着核心作用。	Han, Y.	PDF	N/A	Reductive dehalogenation by diverse microbes is central to biogeochemical cycles in deep-sea cold seeps
用于在多光子荧光显微镜中映射原位网络级神经血管耦合的深度学习流程	Rozak, M. W.	PDF	N/A	A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy
超灵活神经网络：在紧凑的4神经元电路中快速切换逻辑操作	White, A. J.	PDF	N/A	Hyper-Flexible Neural Networks: Rapidly Switching between Logic Operations in a Compact 4-Neuron Circuit
缓慢扩散的营养物质的排斥作用增强了趋向移动源的趋化性	Bloxham, B.	PDF	N/A	Repulsion from slow-diffusing nutrients improves chemotaxis towards moving sources
“撕裂袋机制”：通过整体释放的两侧体（amphiectosomes）的限制性膜破裂释放小细胞外囊泡	Visnovitz, T.	PDF	N/A	A "torn bag mechanism" of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)
一种基于数据驱动的潜变量方法来验证研究领域标准框架	Quah, S. K. L.	PDF	N/A	A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria Framework
人道主义背景下无性繁殖作物面临的病原体和害虫风险：为喀麦隆和埃塞俄比亚制定国家植物健康风险分析	Mouafo-Tchinda, R.	PDF	N/A	Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Toward a national plant health risk analysis for Cameroon and Ethiopia
唾液刺激会影响葡萄酒中香气的释放；一项关于微生物群、生物化学和参与者来源的研究	Ruan, X.	PDF	N/A	Stimulation of saliva affects the release of aroma in wine; a study of microbiota, biochemistry and participant origin
在玉米中进行重复的分化选择实验进化，鉴定出与植物高度相关的SNPs	Tost, M.	PDF	N/A	Experimental evolution in maize with replicated divergent selection identifies plant-height associated SNPs
应用三维相关结构光照明显微镜和X射线断层扫描技术来表征单纯疱疹病毒1型的形态发生过程。	Nahas, K. L.	PDF	N/A	Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis
灵长类动物丘脑核选择抽象规则并塑造前额叶动力学	Phillips, J. M.	PDF	N/A	Primate thalamic nuclei select abstract rules and shape prefrontal dynamics
酵母核糖体蛋白mRNA的3'-非翻译区域决定了同源蛋白在核糖体中的整合，并招募了执行特定功能所需的因子。	Singh, R.	PDF	N/A	The 3'-untranslated regions of yeast ribosomal protein mRNAs determine paralog incorporation into ribosomes and recruit factors necessary for specialized functions
后内侧丘脑在调节纹状体回路和选择行为中的作用	Yonk, A. J.	PDF	N/A	Role of Posterior Medial Thalamus in the Modulation of Striatal Circuitry and Choice Behavior
内皮钙离子爆发介导了转移性肿瘤细胞的渗出。	Peralta, M.	PDF	N/A	Endothelial calcium firing mediates extravasation of metastatic tumor cells.
喀麦隆黑蝇（双翅目：蚋科）携带着大量（RNA）病毒。	De Coninck, L.	PDF	N/A	Cameroonian blackflies (Diptera: Simuliidae) harbour a plethora of (RNA) viruses
多元模型和层次模型的互补优势在识别认知控制中的个体差异方面	Freund, M. C.	PDF	N/A	Complementary benefits of multivariate and hierarchical models for identifying individual differences in cognitive control
识别认知控制中个体差异的多变量和分层模型的互补优势	Freund, M. C.	PDF	N/A	Complementary benefits of multivariate and hierarchical models for identifying individual differences in cognitive control
通过抗环孢子蛋白单克隆抗体在肝脏中延迟杀死恶性疟原虫伯氏疟原虫	Aguirre-Botero, M. C.	PDF	N/A	Late killing of Plasmodium berghei in the liver by an anti-circumsporozoite protein monoclonal antibody
性特异性优势及其对性对抗位点等位基因多样性的影响	Siljestam, M.	PDF	N/A	Sex-Specific Dominance and Its Effects on Allelic Diversity in Sexually Antagonistic Loci
SH3结合基序的邻近残基在体内参与相互作用	Jordan, D. F.	PDF	N/A	Residues Neighboring an SH3-Binding Motif Participate in the Interaction In Vivo
RNA/DNA结合蛋白TDP43调控DNA错配修复基因，对基因组稳定性具有重要意义	Provasek, V.	PDF	N/A	RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability
解析宿主遗传和因素对年轻群体尿液微生物组的影响	Zou, L.	PDF	N/A	Unraveling the impact of host genetics and factors on the urinary microbiome in a young population
对13种突变特征归属工具进行基准测试，包括一种新的改进算法	Jiang, N.	PDF	N/A	Benchmarking 13 tools for mutational signature attribution, including a new and improved algorithm
通过多拷贝质粒上的杂合性实现细菌种群的进化拯救	Dewan, I.	PDF	N/A	Evolutionary rescue of bacterial populations by heterozygosity on multicopy plasmids
Solu - 一个用于实时基因组病原体监测的云平台	Moilanen, T. J.	PDF	N/A	Solu - a Cloud Platform for Real-Time Genomic Pathogen Surveillance
海马重播的空间定位需要多巴胺信号传递	Kleinman, M. R.	PDF	N/A	Spatial localization of hippocampal replay requires dopamine signaling
HistoGWAS：一种利用人工智能实现组织表型自动化遗传分析的框架	Chaudhary, S.	PDF	N/A	HistoGWAS: An AI-enabled Framework for Automated Genetic Analysis of Tissue Phenotypes in Histology Cohorts
力监测揭示了在停止信号任务中运动控制的单次试验动力学	Ramawat, S.	PDF	N/A	Force monitoring reveals single trial dynamics of motor control in a stop signal task
一个共享的威胁预感电路会在不同时刻被确定和不确定的威胁动态地激活。	Cornwell, B. R.	PDF	N/A	A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat
线虫端粒进化中端粒结合蛋白的强健结合能力与偶尔的基因丢失	Song, H.	PDF	N/A	Robust Binding Capability and Occasional Gene Loss of Telomere-Binding Proteins Underlying Telomere Evolution in Nematoda
大规模计算建模分析H5流感变种对抗HA1中和抗体的效果	Ford, C. T.	PDF	N/A	Large-Scale Computational Modeling of H5 Influenza Variants Against HA1-Neutralizing Antibodies
靶向IRE1α可改善胰岛素敏感性、促进产热，并抑制肥胖状态下代谢活跃的脂肪组织巨噬细胞	Wu, D.	PDF	N/A	Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity
高脂饮食相关的蛋白质限制在幼鼠中引起代谢失调，但未导致肥胖	Joly, A.	PDF	N/A	Protein restriction associated with high fat induces metabolic dysregulation without obesity in juvenile mice
短暂的睡眠中断会改变海马体和皮层中表达生长抑素的中间神经元的突触结构	Raven, F.	PDF	N/A	Brief sleep disruption alters synaptic structures among hippocampal and neocortical somatostatin-expressing interneurons
非人灵长类物种在生物医学研究中常见的寿命和健康寿命比较	Huber, H. F.	PDF	N/A	Comparative lifespan and healthspan of nonhuman primate species common to biomedical research
利用扩展拼贴光片显微技术对无性扁形虫的神经元异速生长和神经肌肉投射进行三维重建	Lu, J.	PDF	N/A	3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy
隐球菌新形隐球菌STRIPAK复合物调控基因组稳定性、性发育和毒力	Peterson, P. P.	PDF	N/A	The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence
富含褐藻素的海带提取物抑制流感感染	Mega, D. F.	PDF	N/A	Phlorotannin rich Ascophyllum nodosum seaweed extract inhibits influenza infection
致癌代谢物D-2-羟基戊二酸（D-2-hydroxyglutarate）促进IDH突变型胶质瘤中控制小胶质细胞激活的谱系特异性增强子的DNA高甲基化。	Laurenge, A.	PDF	N/A	The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas
利用体内钙成像技术检测关节神经的自发活动，并通过家庭笼分析监测关节炎小鼠模型中活动变化的情况。	Goodwin, G. L.	PDF	N/A	Using in vivo calcium imaging to examine joint neuron spontaneous activity and home cage analysis to monitor activity changes in mouse models of arthritis
基于活性蛋白质谱分析系统优化，用于在生物治疗药物物质中鉴定低至10 ppb的多聚山梨酯降解酶	Tsukidate, T.	PDF	N/A	Systematic Optimization of Activity-Based Protein Profiling for Identification of Polysorbate-Degradative Enzymes in Biotherapeutic Drug Substance Down to 10 ppb
先前对自身能力的预期会偏差自我信念的形成，并阻碍后续的修正。	Schröder, A.	PDF	N/A	Prior expectations about own abilities bias self-belief formation and hinder subsequent revision
在猕猴下丘中视觉诱发活动与听觉反应的可变调制	Schmehl, M. N.	PDF	N/A	Visually-evoked activity and variable modulation of auditory responses in the macaque inferior colliculus
在斑马鱼神经杆内局部光遗传激活NMYII会导致长距离、不对称的力传导。	Crellin, H. A.	PDF	N/A	Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation
GCK-MODY中独特的持续时间和饮食依赖性脂质谱及肾脏并发症	Huang, Y.	PDF	N/A	Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
结构导向设计、合成及表征C22和C32修饰的FK520类似物，其对人致病真菌的活性增强	Dome, P. A.	PDF	N/A	Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi
使用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层层特定区域边界	Autio, J. A.	PDF	N/A	Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI
独特的表达谱揭示了三叉神经系统中胶质细胞的参与，这与创伤后头痛有关。	Nagarajan, G.	PDF	N/A	Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache
海洋杜父鱼成对胸鳍上的表皮微结构提示了新的功能假说，支持其在底栖环境中的固定栖息。	Kane, E. A.	PDF	N/A	Epidermal microstructures on the paired fins of marine sculpins suggest new functional hypotheses supporting benthic station-holding
使用肌电图进行可泛化的手势识别	Yun, R.	PDF	N/A	Generalizable gesture recognition usingmagnetomyography
一种用于大鼠在空间条件下自发探索和操作性条件化社会信息的新型行为装置	Wise, T. B.	PDF	N/A	A novel behavioral apparatus for spontaneous exploration and operant conditioning of social information under spatial conditions in rats
高通量优化基于纸的免细胞生物传感器	Garcia, D. C.	PDF	N/A	High-Throughput Optimization of Paper-Based Cell-Free Biosensors
多聚腺苷酸酶PAPI在致病菌中对毒力质粒的维持是必需的。	Schubert, K.	PDF	N/A	The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria
窦房结细胞中兰尼碱受体簇网络的结构-功能关系	Maltsev, A. V.	PDF	N/A	Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells
股二头肌长头的远端激活程度更大，反映了运动单位动作电位性质的近端到远端的差异。	Albarello, J. C. d. S.	PDF	N/A	Greater distal activation of the biceps femoris long head reflects proximodistal differences in motor unit action potential properties.
APOE基因型和生物学年龄影响与生物能量学相关的多组学关联	Ellis, D. S.	PDF	N/A	APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics
肌球蛋白轻链3作为神经坏死病毒通过巨胞饮途径进入宿主细胞的受体	Yao, L.	PDF	N/A	Myosin light chain 3 serves as a receptor for nervous necrosis virus entry into host cells via the macropinocytosis pathway
从牛胚胎干细胞生成培养牛肉	Rui, X.	PDF	N/A	Generation of cultured beef from bovine embryonic stem cells
芳香族氨基酸相互作用强度的交叉：酪氨酸与苯丙氨酸在生物分子凝聚物中的对比	De Sancho, D.	PDF	N/A	Crossover in Aromatic Amino Acid Interaction Strength: Tyrosine vs. Phenylalanine in Biomolecular Condensates
欧洲人畜共患的蜱传脑炎（TBE）发生概率的时空年度变化建模	Dagostin, F.	PDF	N/A	Modeling spatio-temporal annual changes in the probability of human tick-borne encephalitis (TBE) occurrence across Europe
脂质分离降低了高曲率囊泡出芽的能垒	Schachter, I.	PDF	N/A	Lipid Demixing Reduces Energy Barriers for High Curvature Vesicle Budding
用于细胞表面跨膜光学和化学标记的工具	Innes-Gold, S.	PDF	N/A	Tools for intersectional optical and chemical tagging on cell surfaces
真菌毒素念珠菌素在芯片肠道模型中破坏上皮屏障完整性并引发炎症	Morelli, M.	PDF	N/A	Fungal toxin candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model
毒力因子念珠菌素在芯片肠道模型中破坏上皮屏障完整性并引发炎症	Morelli, M.	PDF	N/A	Virulence factor candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model
Squeakuences：一种便携式工具，用于格式化干净无瑕的序列，以消除生物信息学软件的不兼容性	Lane, L. E.	PDF	N/A	Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities
揭开睡眠之谜：探索近期在洛基城堡附近发现的古菌门Lokiarchaeota中的系统基因组睡眠信号	Pandi-Perumal, S. R.	PDF	N/A	Unraveling the Mysteries of Sleep: Exploring Phylogenomic Sleep Signals in the Recently Characterized Archaeal Phylum Lokiarchaeota near Loki's Castle
利用苦艾叶提取物进行生物银纳米粒子的植物辅助合成：表征、抗菌、抗炎及急性毒性特征	Nyuyfoni, G. F.	PDF	N/A	Phytoassisted synthesis of biogenic silver nanoparticles using Vernonia amygdalina leaf extract: characterization, antibacterial, anti-inflammatory, and acute toxicity profile
ABRpresto：一种利用子平均间的重采样互相关进行听觉脑干反应自动阈值设定的算法	Shaheen, L. A.	PDF	N/A	ABRpresto: An algorithm for automatic thresholding of the Auditory Brainstem Response using resampled cross-correlation across subaverages
通过X射线晶体学鉴定出的电压门控钠通道中对挥发性麻醉剂具有功能重要性的结合位点	Hollingworth, D.	PDF	N/A	Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography
dArc1调控果蝇糖奖励的评价	Bervoets, S.	PDF	N/A	dArc1 controls sugar reward valuation in Drosophila melanogaster
用勺子处理空间分辨转录组数据中的均值-方差关系	Shah, K. H.	PDF	N/A	Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon
通过剪接进化的视角增强转录组注释	Zang, X. C.	PDF	N/A	Augmenting Transcriptome Annotations through the Lens of Splicing Evolution
Rthoptera：R语言中的标准化昆虫生物声学分析	Rivas, F.	PDF	N/A	Rthoptera: standardised insect bioacoustics in R
基于单个神经元活动的前额叶皮层图谱	Le Merre, P.	PDF	N/A	A Prefrontal Cortex Map based on Single Neuron Activity
鹦鹉发声学习能力的进化	Krasheninnikova, A.	PDF	N/A	Evolution of vocal production learning in parrots
通过厌氧光敏化实现产油微藻培养的阿克森化。	Iyer, A.	PDF	N/A	Axenisation of oleaginous microalgal cultures via anoxic photosensitisation.
抗噬菌体防御中的淀粉样蛋白信号	Ibarlosa, L.	PDF	N/A	Amyloid signaling in antiphage defense
视蛋白的海洋	De Vivo, G.	PDF	N/A	An ocean of opsins
CosinorTest：一个基于Cosinor模型的转录组应用中的昼夜节律和差异分析R Shiny应用程序	Ding, H.	PDF	N/A	CosinorTest: An R Shiny App for Cosinor-model-based circadian and differential analysis in transcriptomic applications
在意识障碍的多种恢复过程中，一个统一的中央丘脑机制	Zhang, H.	PDF	N/A	A unified central thalamus mechanism underlying diverse recoveries in disorders of consciousness
生命周期中噪声环境下的语音感知：蒙古沙鼠与人类的比较研究	Juchter, C.	PDF	N/A	Speech-in-noise perception across the lifespan: A comparative study in Mongolian gerbils and humans
利用RESA作为代表性标记蛋白，通过超微结构扩展显微镜（U-ExM）对疟原虫致密颗粒进行可视化研究	Fukumoto, J.	PDF	N/A	Ultrastructural expansion microscopy (U-ExM) visualization of malaria parasite dense granules using RESA as a representative marker protein
对两种稀有鲸类物种解剖学的贡献：虎鲸（Lagenorhynchus cruciger）和眼镜海豚（Phocoena dioptrica）	Graic, J.-M.	PDF	N/A	A CONTRIBUTION TO THE ANATOMY OF TWO RARE CETACEAN SPECIES: THE HOURGLASS DOLPHIN (Lagenorhynchus cruciger) AND THE SPECTACLED PORPOISE (Phocoena dioptrica)
对紫杉树进行多重扰动揭示了能够实现巴卡亭III和紫杉醇前体全生物合成的隐秘蛋白质	McClune, C. J.	PDF	N/A	Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors
基于算法的研究揭示了蛋白质腔内水在不同距离壁面处的差异动力学	Francis, A. X.	PDF	N/A	An algorithm-based investigation reveals the differential dynamics of water inside protein cavity as a function of distance from its wall
建模溶瘤痘苗病毒疗法突显了中性粒细胞对肿瘤抑制的影响	Satani, S.	PDF	N/A	Modeling Oncolytic Vaccinia Virus Therapy Highlights Neutrophil Impact on Tumor Suppression
希望他人：匹兹堡大学乳腺癌快速尸检计划的研究成果	Chang, A. C.	PDF	N/A	Hope for Others: Research Results from the University of Pittsburgh Rapid Autopsy Program for Breast Cancer
脑功能连接作为血液学指标与儿童β地中海贫血主要型认知衰退之间的中介因素	Xu, S.	PDF	N/A	Brain functional connectivity as a mediator between hematological metrics and cognitive decline in children with beta-thalassemia major
抑郁和焦虑障碍中基底前脑对内在脑网络的调控改变	Jamieson, A. J.	PDF	N/A	Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders
与侵染华山松的树皮甲虫相关的长喙壳菌，并描述了来自中国西部的七个新种	Chen, M.	PDF	N/A	Ophiostomatoid fungi associated with bark beetles infesting Pinus armandii, with characterizations of seven new species from western China
与感染马尾松的黄毛脊虎天牛相关的长喙壳菌，包括在中国新描述的青原真菌新种的特征	Liu, K.	PDF	N/A	Ophiostomatalean fungi associated with Cyrtogenius luteus infested Pinus massoniana, including characterization of Masuyamyces qingyuanensis sp. nov. in China
次氯酸在感染中的应用：科学文献的文献计量分析	Ates, F. M.	PDF	N/A	Use of Hypochlorous Acid in Infections: Bibliometric Analysis of Scientific Literature
通过丝状纳米团簇的蛋白质-RNA凝聚动力学	Peralta Martinez, R.	PDF	N/A	Protein-RNA condensation kinetics via filamentous nanoclusters
TRPV4过度激活增强了细胞收缩力，并在TGFβ2过表达的眼中驱动眼压升高。	Rudzitis, C. N.	PDF	N/A	TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes
通过泛基因组学鉴定和表征古菌假胞壁酸生物合成基因	Lupo, V.	PDF	N/A	Identification and Characterization of Archaeal Pseudomurein Biosynthesis Genes through Pangenomics
拟南芥中着丝粒和纺锤体组装检查点的功能框架	Pettko-Szandtner, A.	PDF	N/A	Functional framework of the kinetochore and spindle assembly checkpoint in Arabidopsis thaliana
邻近蛋白质组学为探索Afadin功能及细胞间粘附连接的复杂性提供了新的资源。	Choi, W.	PDF	N/A	Proximity proteomics provides a new resource for exploring the function of Afadin and the complexity of cell-cell adherens junctions
中心体蛋白-Sfi1的渔网状网格驱动巨型细胞Spirostomum ambiguum的超快钙激活收缩	Lannan, J.	PDF	N/A	Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum
中心粒-Sfi1的渔网状网格驱动巨型细胞Spirostomum ambiguum的超快钙激活收缩	Lannan, J.	PDF	N/A	Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum
跨膜耦合加速液态蛋白质凝聚物的生长	Lee, Y.	PDF	N/A	Transmembrane coupling accelerates the growth of liquid-like protein condensates
昼夜节律钟调控对植食性动物相关分子模式的受体介导免疫反应	Palacios, N. G.	PDF	N/A	The circadian clock regulates receptor-mediated immune responses to an herbivore-associated molecular pattern
在玉米的热胁迫过程中，自噬、未折叠蛋白反应与细胞质热胁迫反应之间的相互作用	Tang, J.	PDF	N/A	Interplay between autophagy, the unfolded protein response and the cytoplasmic heat stress response during heat stress in maize
天然细菌素作为潜在药物候选，靶向奶牛乳腺炎病原体的核心蛋白质	Hasnat, S.	PDF	N/A	Natural Bacteriocins as Potential Drug Candidates Targeting Core Proteins in Mastitis Pathogens of Dairy Cattle
P4HA1基因敲除小鼠乳腺基因调控网络的单细胞分析	Gupta, A.	PDF	N/A	Single-Cell Analysis of Gene Regulatory Networks in the Mammary Glands of P4HA1-knockout mice
研究内源性大麻素诱导的短杆菌肽电流变化	Mayar, S.	PDF	N/A	Examining Changes in Gramicidin Current Induced by Endocannabinoids
奈拉替尼，一种用于治疗乳腺癌的临床药物，通过抑制ASK1来预防动脉粥样硬化。	Zhang, F.	PDF	N/A	Neratinib, a clinical drug against breast cancer, protects against atherosclerosis via ASK1 inhibition
从空中无人机到数量性状位点（QTL）：利用新一代表型分析揭示田间种植的莴苣（Lactuca sativa）中颜色和高度的遗传机制	Dijkhuizen, R. F.	PDF	N/A	From aerial drone to QTL: Leveraging next-generation phenotyping to reveal the genetics of color and height in field-grown Lactuca sativa
父本来源的基因组通过母本植物抑制拟南芥种子的休眠诱导	Barros-Galvao, T.	PDF	N/A	The paternally derived genome opposes seed dormancy induction by the mother plant in Arabidopsis
高效多用途的油菜转化技术助力新育种技术的发展	Ille, K.	PDF	N/A	Efficient and Versatile Rapeseed Transformation for New Breeding Technologies
从数量性状位点到机制：连锁整合假设检验（LIgHT）揭示了遗传调控的应激耐受机制	Hoh, D.	PDF	N/A	From Quantitative Trait Loci towards Mechanisms: Linkage Integration Hypothesis Testing (LIgHT) Sheds Light on the Mechanisms of Genetically Modulated Stress Tolerance
OsMORF蛋白特异性地促进双定位RNA编辑因子OsPGL1与其目标RNA的结合	Xiao, H.	PDF	N/A	OsMORF protein selectively promotes the dual-localized RNA editing factor OsPGL1 binding to its target RNA
茉莉酸通过嘌呤受体P2K1介导植物对外源性ATP的响应	Jewell, J. B.	PDF	N/A	Jasmonate Primes Plant Responses to Extracellular ATP through Purinoceptor P2K1
双NBT方法：利用MdAGG防御凝集素通过基因编辑和内生化促进苹果抗火疫病。	Bodelot, A.	PDF	N/A	Dual NBT Approach: Gene Editing and Intragenesis to promote Fire Blight Resistance in Apple using MdAGG defense lectins.
一种富含藻类营养、优化的培养基，适用于快速生长和高甘油三酯积累	Jeffers, T. L.	PDF	N/A	An algal nutrient-replete, optimized medium for fast growth and high triacylglycerol accumulation
时间和温度解析的拟南芥剪接相关突变体的转录组分析	Nardeli, S. M.	PDF	N/A	Time and temperature-resolved transcriptomic analysis of Arabidopsis splicing-related mutants
CCR2介导的单核细胞招募对放射治疗引起的肠道毒性具有保护作用	Pun, N.	PDF	N/A	CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity
丛枝菌根真菌基因型及其核组织作为宿主植物营养获取和稳定碳捕获的驱动因素	Ferguson, R.	PDF	N/A	Arbuscular mycorrhizal fungal genotype and nuclear organization as driving factors in host plant nutrient acquisition and stable carbon capture
防御性共生体以低成本为宿主提供高水平的自然敌害防护：一项元分析	Cesar, C. S.	PDF	N/A	Defensive symbionts provide high protection against natural enemies at low cost to hosts: a meta-analysis
凝聚素II复合物在红细胞生成过程中调控必需基因表达程序的表达	Abid, D.	PDF	N/A	The Condensin II Complex Regulates the Expression of Essential Gene Expression Programs During Erythropoiesis
多组学潜在变量数据整合揭示了乌干达结核菌素皮肤试验（TST）/干扰素伽马释放试验（IGRA）转化抗性相关的多细胞结构途径	Cox, M. S.	PDF	N/A	Multi-omic latent variable data integration reveals multicellular structure pathways associated with resistance to tuberculin skin test (TST)/interferon gamma release assay (IGRA) conversion in Uganda
机器学习揭示了胶质母细胞瘤和骨肉瘤的新靶点	Li, N.	PDF	N/A	Machine learning reveals novel targets for both glioblastoma and osteosarcoma
使用时空图卷积网络对大脑fMRI数据进行肠易激综合征分类	Wu, J.	PDF	N/A	Classifying Irritable Bowel Syndrome Using Spatio-Temporal Graph Convolution Networks on Brain fMRI Data
DrugProtAI：探索性靶蛋白未来研究指南	Halder, A.	PDF	N/A	DrugProtAI: A guide to the future research of investigational target proteins
NovumRNA：从RNA测序数据中准确预测非经典肿瘤抗原	Ausserhofer, M.	PDF	N/A	NovumRNA: accurate prediction of non-canonical tumor antigens from RNA sequencing data
PDBe工具，用于对蛋白质数据库中的小分子进行深入分析	Choudhary, P.	PDF	N/A	PDBe tools for an in-depth analysis of small molecules in the Protein Data Bank
棒的棒：淀粉样蛋白肽-DNA复合物的结构特征	Arzamastsev, G.	PDF	N/A	Stick of Sticks: Structural Features of the Amyloidogenic Peptide-DNA Complex
细胞-基质机械反馈中的关键间距控制组织凝集	Peng, X.	PDF	N/A	Critical Spacing in Cell-Matrix Mechanical Feedback Controls Tissue Condensation
空间多组学在胶质母细胞瘤切除边缘定义了一个共同的浸润特征	Pai, B.	PDF	N/A	Spatial multi-omics defines a shared infiltrative signature in glioblastoma at the resection margin
一种SH3结合的变构调节剂稳定了与AML相关的Src家族激酶Hck的全局构象	Selzer, A. M.	PDF	N/A	An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck
SysQuan：将SILAC小鼠用于人类蛋白质组经济实惠的绝对定量	Mohammed, Y.	PDF	N/A	SysQuan: repurposing SILAC mice for the affordable absolute quantitation of the human proteome
通过选择性光遗传激活海马切片中的门牙细胞，研究齿状回颗粒细胞的场EPSP。	Bernstein, H. L.	PDF	N/A	Field EPSPs of dentate gyrus granule cells studied by selective optogenetic activation of hilar mossy cells in hippocampal slices.
探究习惯性睡眠质量对情景记忆表现的影响：基于脑电图的表征相似性分析	Seraji, M.	PDF	N/A	Investigating the Impact of Habitual Sleep Quality on Episodic Memory Performance: An EEG-Based Representational Similarity Analysis
整合的高维分析揭示了CD4 T细胞表位特异性和表型在应对结核分枝杆菌反应中的出乎意料的多样性	Mead, H. L.	PDF	N/A	Integrated, high-dimensional analysis of CD4 T cell epitope specificities and phenotypes reveals unexpected diversity in the response to Mycobacterium tuberculosis
淡水SAR11（LD12）中的聚羟基丁酸酯生产	Bennett, B. D.	PDF	N/A	Polyhydroxybutyrate production in freshwater SAR11 (LD12)
p53的参与是哺乳动物细胞核中未折叠蛋白反应的标志。	Park, J. H.	PDF	N/A	p53 engagement is a hallmark of an unfolded protein response in the nucleus of mammalian cells
通过二次抽样：推断生物多样性随时间和跨研究者的变化	Elahi, R.	PDF	N/A	Passing the quadrat: inferring biodiversity change over time and across investigators
气候变化对草本旋花科植物在塞拉多和大西洋森林生物群落（巴西东南部）的影响：高温是否成为杂草的威胁？	Barbosa, J. C. J.	PDF	N/A	Too hot for the weeds? Exploring the impact of climate change in herbaceous Convolvulaceae in Cerrado and Mata Atlantica biomes (SE Brazil)
体型大小和栖息地破碎化如何影响蜥蜴的灭绝？一项关于巴西塞拉多地区人工岛屿的长期案例研究	Miranda, R. B.	PDF	N/A	How do body size and habitat fragmentation influence extinction in lizards? A long-term case study on artificial islands in the Brazilian Cerrado
松鱼（Lagodon rhomboides）具有广泛的温度耐受性和高度的线粒体基因连通性。	Eaton, K. M.	PDF	N/A	Broad thermal tolerance and high mitochondrial genetic connectivity in the pinfish (Lagodon rhomboides)
重复扩增的并行深度分析：适用于纳米孔R10流式细胞仪的更新版Clin-CATS工作流程	Scholz, V.	PDF	N/A	Parallel in-depth analysis of repeat expansions: an updated Clin-CATS workflow for nanopore R10 flow cells
利用特征选择算法表征石珊瑚组织丧失病中不同组织状态的基因表达谱	Beavers, K. M.	PDF	N/A	Characterizing gene expression profiles of various tissue states in stony coral tissue loss disease using a feature selection algorithm
优化聚合物纳米颗粒上Angiopep-2的密度以增强血脑屏障穿透和胶质母细胞瘤靶向：来自体外和体内实验的见解	Zhang, W.	PDF	N/A	Optimizing Angiopep-2 Density on Polymeric Nanoparticles for Enhanced Blood-Brain Barrier Penetration and Glioblastoma Targeting: Insights from In Vitro and In Vivo Experiments
体内工程化四价CAR巨噬细胞通过抗原扩散突破肿瘤屏障，重塑肿瘤微环境，并克服肿瘤异质性。	Zhang, S.	PDF	N/A	In vivo engineered quadrivalent CAR-macrophages break tumor barrier,remodel TME and overcome tumor heterogeneity through antigen spreading
长读多重多样单体型重建	Shaw, J.	PDF	N/A	devider: long-read reconstruction of many diverse haplotypes
扩展和改进的全鼠脑CCFv3注释和尼氏图谱	Piluso, S.	PDF	N/A	An extended and improved CCFv3 annotation and Nissl atlas of the entire mouse brain
使用可解释深度学习预测特定上下文调控程序和通路	Doncevic, D.	PDF	N/A	Prediction of context-specific regulatory programs and pathways using interpretable deep learning
绘制甲状腺肿瘤的分子图谱：对源于滤泡的肿瘤进行全面的蛋白质组学和磷酸蛋白质组学分析	Bossart, J.	PDF	N/A	Mapping the Molecular Landscape of Thyroid Neoplasms: A Comprehensive Proteomic and Phosphoproteomic Analysis Across Tumors of Follicular Origin
可解释的PROTAC降解预测：基于结构信息的深度三元注意力框架	Chen, Z.	PDF	N/A	Interpretable PROTAC degradation prediction with structure-informed deep ternary attention framework
一种精确且快速的SAT公式化方法用于DCJ距离计算	Sarnaik, A. M.	PDF	N/A	An Exact and Fast SAT Formulation for the DCJ Distance
揭示核小体动态：利用全原子与粗粒化模拟并结合主成分分析的比较研究	MOULICK, A. G.	PDF	N/A	Unveiling Nucleosome Dynamics: A Comparative Study Using All-Atom and Coarse-Grained Simulations Enhanced by Principal Component Analysis
工程化的乙酰化模式在体外驱动大规模染色质组织	Fukai, Y.	PDF	N/A	Engineered acetylation patterns drive large-scale chromatin organization in vitro
粘性酶：通过底物依赖的酶聚集提高代谢效率	Martinez-Calvo, A.	PDF	N/A	Sticky enzymes: increased metabolic efficiency via substrate-dependent enzyme clustering
一种多模态深度学习框架，结合了序列和结构信息，用于肿瘤抗原预测	Jin, R.	PDF	N/A	A Multi-Modal Deep Learning Framework with Both Sequence and Structure for Tumor Antigens Prediction
表观遗传学中的分数阶微积分	Nasrolahpour, H.	PDF	N/A	Fractional Calculus in Epigenetics
耐力运动通过儿童期和成年期提高血浆成熟脑源性神经营养因子水平，成年期的效果更为显著。	Edman, S.	PDF	N/A	Endurance Exercise Elevates Plasma Mature Brain-Derived Neurotrophic Factor through Child- and Adulthood, with Amplified Effects in Adults
RTF1通过H2B单泛素化介导Th17细胞分化的表观遗传调控	Galan, C.	PDF	N/A	RTF1 mediates epigenetic control of Th17 cell differentiation via H2B monoubiquitination
释放引进的寄生虫不会影响它们的建立或成功。	Kishinevsky, M.	PDF	N/A	Enemy release of introduced parasitoids does not affect their establishment or success
全基因组测序跨越时间和空间揭示了佛罗里达灌丛鸦种群数量下降和基因流动减少的影响。	Nguyen, T. N.	PDF	N/A	Whole-genome sequencing across space and time reveals impact of population decline and reduced gene flow in Florida Scrub-Jays
JOnTADS：Hi-C数据中TADs和条纹的统一调用器	Zeng, Q.	PDF	N/A	JOnTADS: a unified caller for TADs and stripes in Hi-C data
基于人工智能增强的物理学对接用于抗体-抗原复合物预测	Gaudreault, F.	PDF	N/A	AI-Augmented Physics-Based Docking for Antibody-Antigen Complex Prediction
分子模拟与个性化医疗的结合：ClC-5反向转运体的机制及其与Dent病的起源	Macaluso, V.	PDF	N/A	Molecular Simulations Meet Personalized Medicine. The Mechanism of Action of ClC-5 Antiporter and the Origin of Dent's Disease
在模拟无序蛋白质的过程中，将折叠过程与能量陷阱分离开来	Lotthammer, J. M.	PDF	N/A	Disentangling folding from energetic traps in simulations of disordered proteins
泪腺通过细胞旁途径分泌泪液的过程受到肌球蛋白介导的紧密连接通透性调节的调控。	Ohno, Y.	PDF	N/A	Tear secretion via a paracellular pathway in lacrimal gland is regulated by myosin-mediated modulation of tight junction permeability
颗粒形成型Ca. Accumulibacter富集物分泌组学的元蛋白质组学分析	van Olst, B.	PDF	N/A	Metaproteomic profiling of the secretome of a granule-forming Ca. Accumulibacter enrichment
多维社会关系塑造了猴子的社会注意力	Liu, S.	PDF	N/A	Multi-dimensional social relationships shape social attention in monkeys
行为和神经证据表明，在社交互动中存在感知预测	Lu, J.	PDF	N/A	Behavioral and neural evidence for perceptual predictions in social interactions
在视紫红质P23H大鼠模型中，通过利血平实现性别的光感受器退行性变减弱，该模型用于研究常染色体显性遗传性视网膜色素变性	Song, H. B.	PDF	N/A	Sex-specific attenuation of photoreceptor degeneration by reserpine in a rhodopsin P23H rat model of autosomal dominant retinitis pigmentosa
ENaC参与了囊性纤维化中巨噬细胞功能障碍的发生	Moran, J.	PDF	N/A	ENaC contributes to macrophage dysfunction in cystic fibrosis
爱泼斯坦-巴尔病毒潜伏膜蛋白1通过劫持IMPDH通路驱动B细胞癌代谢	Burton, E.	PDF	N/A	Epstein-Barr Virus Latent Membrane Protein 1 Subverts IMPDH pathways to drive B-cell oncometabolism
生物毒素BMAA促进神经母细胞瘤细胞的间充质转化	Moore, E.	PDF	N/A	The biotoxin BMAA promotes mesenchymal transition in neuroblastoma cells
LUMIC：用于细胞多重成像的潜在扩散模型	Hung, A. Z.	PDF	N/A	LUMIC: Latent diffUsion for Multiplexed Images of Cells
肌营养不良蛋白与Msp300相互作用，调控肌核定位与微管组织	Padilla, J. R.	PDF	N/A	Dystrophin interacts with Msp300 to Regulate Myonuclear Positioning and Microtubule Organization
绿化速率对方法论和生物学敏感；评论：卫星观测到的南极半岛持续绿化现象	Bokhorst, S.	PDF	N/A	Greening rates are sensitive to methodology and biology; comment to Sustained greening of the Antarctic Peninsula observed from satellites
自由生活鸣禽的表观遗传潜能与扩散倾向：一种时空方法	Jimeno, B.	PDF	N/A	Epigenetic potential and dispersal propensity in a free-living songbird: a spatial and temporal approach
栖息地数量和碎片化本身对格兰特维尔小灰蝶遗传多样性的相对影响	Fernandez Multigner, L.	PDF	N/A	Relative Effects of Habitat Amount and Fragmentation Per Se on the Genetic Diversity of The Glanville Fritillary Butterfly
从二进制数据中识别简约的积累路径和趋同进化	Giannakis, K.	PDF	N/A	Identifying parsimonious pathways of accumulation and convergent evolution from binary data
反向共敏性可恢复抗生素敏感性	Chowdhury, F. R.	PDF	N/A	Backward collateral sensitivity can restore antibiotic susceptibility
SelNeTime：一个从基因组时间序列数据推断有效种群大小和选择强度的Python包	Uhl, M.	PDF	N/A	SelNeTime: a python package inferring effective population size and selection intensity from genomic time series data
通过Voronoi方法在空间转录组学中进行综合细胞分箱分割	Lin, M.	PDF	N/A	Integrative cell bin segmentation on spatial transcriptomics by Voronoi
无虹膜症患者血浆中PAX6半合子不足引起的代谢和神经活性失衡	Cunha, D. L.	PDF	N/A	Metabolic and neuroactivity imbalances in plasma from aniridia patients with PAX6 haploinsufficiency
进化引导的转录因子设计程序可产生新型T细胞状态	Takacsi-Nagy, O.	PDF	N/A	Evolutionarily guided transcription factor design programs novel T cell states
GCfix：一种快速且精确的片段长度特异性方法，用于校正无细胞DNA中的GC偏倚	Rafeed, C.	PDF	N/A	GCfix: A Fast and Accurate Fragment Length-SpecificMethod for Correcting GC Bias in Cell-Free DNA
基于图像的低嵌合体体细胞移动元件插入检测的DNA测序编码	Tan, M.	PDF	N/A	Image-based DNA Sequencing Encoding for Detecting Low-Mosaicism Somatic Mobile Element Insertions
蓝宝石雀鲷（Chrysiptera cyanea）的基因组：支持进一步研究雀鲷科进化的新资源	Gairin, E.	PDF	N/A	The genome of the sapphire damselfish Chrysiptera cyanea: a new resource to support further investigation of the evolution of Pomacentrids
多功能体外生命支持（ECLS）系统用于肺和肾脏支持的开发：Pneuma-K ECLS系统	Kwon, J.	PDF	N/A	Development of a Multifunctional Extracorporeal Life Support (ECLS) System for Lung and Kidney Support: The Pneuma-K ECLS System
对羟基苯甲酸酯对子宫胶原蛋白的影响：利用二次谐波产生显微镜、纳米压痕和原子力显微镜的综合与靶向相关性方法	Arshee, M. R.	PDF	N/A	Impact of Paraben on Uterine Collagen: An Integrated and Targeted Correlative Approach Using Second Harmonic Generation Microscopy, Nanoindentation, and Atomic Force Microscopy
利用微米级tPA珠粒实现高纤溶酶通量和加速纤维蛋白溶解	Osmond, M. J.	PDF	N/A	Harnessing micrometer-scale tPA beads for high plasmin flux and accelerated fibrinolysis
scHiCcompare: 一个用于单细胞Hi-C数据差异分析的R包	Nguyen, M.	PDF	N/A	scHiCcompare: an R package for differential analysis of single-cell Hi-C data
BaNDyT：分子动力学轨迹的贝叶斯网络建模	Mukhaleva, E.	PDF	N/A	BaNDyT: Bayesian Network modeling of molecular Dynamics Trajectories
人类免疫系统的单细胞图谱揭示了免疫衰老的性别特异性动态	Rios, M. S.	PDF	N/A	Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence
缓步动物Dsup：与DNA的相互作用及对细胞氧化应激的保护作用	Ni, G. S.	PDF	N/A	Tardigrade Dsup: Interactions with DNA and protection of cells from oxidative stress
去噪揭示蛋白质晶体中的低占有率群体	Fadini, A.	PDF	N/A	Denoising Reveals Low-Occupancy Populations in Protein Crystals
阐明UBA7-UBE2L6二硫键复合物形成的机制	Chen, P.-T.	PDF	N/A	Elucidating the Mechanism Underlying UBA7-UBE2L6 Disulfide Complex Formation
铜在癌细胞中诱导p53的展开，导致癌细胞的侵袭性和化学耐药性。	Muller, P. A. J.	PDF	N/A	Copper induces p53 unfolding in cancer cells, resulting in invasion and chemoresistance
YY1通过与前列腺癌微环境中巨噬细胞内的NUSAP1相互作用，增强了HIF-1α蛋白的稳定性。	Li, W.	PDF	N/A	YY1 Enhances the Stability of HIF-1α Protein by Interacting with NUSAP1 in Macrophages within the Prostate Cancer Microenvironment
乌特罗司德B，一种被美国FDA指定用于治疗肝细胞癌（HCC）的孤儿药，能够抑制非酒精性脂肪性肝炎（NASH）及其诱发的肝细胞癌。	Rayginia, T. P.	PDF	N/A	Uttroside B, a US-FDA-Designated Orphan Drug Against Hepatocellular Carcinoma (HCC), Impedes Non-alcoholic Steatohepatitis (NASH) and NASH -Induced HCC
拓扑异构酶IIb结合是癌症基因组中频繁突变元素的基础	Uusküla-Reimand, L.	PDF	N/A	Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes
人脂肪来源的间充质基质细胞改善了肠皮瘘疾病小鼠模型中的伤口愈合	Marsiano, N.	PDF	N/A	Human adipose-derived mesenchymal stromal cells improved wound healing in enterocutaneous fistulizing disease mouse model
扭矩与功率在速度之间的权衡：一项关于等速和多平面任务中肩部表现的	Lee, K. D. L.	PDF	N/A	The Trade-Off Between Torque and Power with Speed: A Study of Shoulder Performance During an Isokinetic and Multiplanar Task
解锁基因库的力量：碱基生长温度的多样性为气候智能型农业提供了机遇	Gambart, C.	PDF	N/A	Unlocking the power of gene banks: diversity in base growth temperature provides opportunities for climate-smart agriculture
补充维生素D的肥胖小鼠的胰腺变化	da Rocha, G.	PDF	N/A	Pancreatic changes in obese mice supplemented with vitamin D
TREK K2P通道的热敏感性受PKA开关控制，并依赖于微管网络。	Cordeiro, S.	PDF	N/A	Thermosensitivity of TREK K2P channels is controlled by a PKA switch and depends on the microtubular network
子宫内膜蜕膜反应的停滞决定了流产风险的复发风险	Muter, J.	PDF	N/A	Stalling of the endometrial decidual reaction determines the recurrence risk of miscarriage risk
加拿大科学研究生的津贴低于贫困线。	Fraass, A. J.	PDF	N/A	Canadian science graduate stipends lie below the poverty line
加拿大科学研究生的津贴低于贫困线。	Fraass, A. J.	PDF	N/A	Canadian science graduate stipends lie below the poverty line
单细胞转录组数据中骨骼肌再生细胞群体动力学的微分方程建模	Al-Ghazawi, R.	PDF	N/A	Differential Equation Modeling of Cell Population Dynamics in Skeletal Muscle Regeneration from Single-Cell Transcriptomic Data
人类阿尔茨海默病脑组织中批量RNAseq研究的系统综述与荟萃分析	Heberle, B. A.	PDF	N/A	Systematic review and meta-analysis of bulk RNAseq studies in human Alzheimer's disease brain tissue
人类NMNAT2的转录调控：来自三维基因组测序和生物信息学的见解	Chang, Y. C.	PDF	N/A	Transcriptional Regulation of human NMNAT2: Insights from 3D Genome Sequencing and Bioinformatics
通过实时面部处理对首发精神病的深度多模态表征与分类	Singh, R.	PDF	N/A	Deep Multimodal Representations and Classification of First-Episode Psychosis via Live Face Processing
解码有向句法结构构建的神经动力学	Zhao, J.	PDF	N/A	Decoding the Neural Dynamics of Headed Syntactic Structure Building
一种针对NIMA相关激酶7（NEK7）的脑素（CRBN）分子胶降解剂揭示了其在NLRP3炎症小体激活中的情境依赖性作用	Sylvain, A.	PDF	N/A	A cereblon (CRBN) molecular glue degrader of NIMA-related kinase 7 (NEK7) reveals a context-dependent role in NLRP3 inflammasome activation
莱姆病螺旋体伯氏疏螺旋体（Borreliella burgdorferi）的外表面蛋白C（OspC）顶端的一个特定类型的B细胞表位	Vance, D.	PDF	N/A	A type-specific B cell epitope at the apex of Outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi
我们是否在血清学上为禽流感大流行做好了准备？季节性流感疫苗能否帮助我们？	Sanz-Munoz, I.	PDF	N/A	Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us?
一种用于金黄色葡萄球菌毒力因子共价靶向的mRNA展示方法	Wang, S.	PDF	N/A	An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor
一种用于金黄色葡萄球菌毒力因子共价靶向的mRNA展示方法	Wang, S.	PDF	N/A	An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor
GCTransNet：基于全局上下文视觉变换器的3D线粒体实例分割	Chen, C.	PDF	N/A	GCTransNet: 3D mitochondrial instance segmentation based on Global Context Vision Transformers
探索肥胖青少年在接受减重手术后代谢改善中的器官特异性细胞外囊泡	Kim, A.	PDF	N/A	Exploring Organ-Specific Extracellular Vesicles in Metabolic Improvements Following Bariatric Surgery in Adolescents with Obesity
索诺兰沙漠异地保护差距分析：绘制保护之路	Hernandez, M. G. C.	PDF	N/A	Sonoran Desert ex situ conservation gap analysis: charting the path towards conservation
希腊中部尖音库蚊成蚊的越冬	Ioannou, C.	PDF	N/A	Winter Survival of Culex pipiens f. pipiens Adults in Central Greece
一种应用于物种分布模式机制模型的顺序采样新算法	Kristensen, N. P.	PDF	N/A	A novel sequential sampling algorithm for the application of mechanistic models to species occurrence patterns
埃塞俄比亚东部哈拉马亚大学辣椒（Capsicum annuum.L）地方品种的遗传变异性分析。	Sufiyan, A.	PDF	N/A	Genetic Variability Analysis of Hot Pepper (Capsicum annuum.L) Landraces at Haramaya University, Eastern Ethiopia.
人类异种代谢蛋白在肠道微生物群中具有全长和分裂的同源物	Rendina, M.	PDF	N/A	Human xenobiotic metabolism proteins have full-length and split homologs in the gut microbiome
S1P与硫酸肝素衍生物联合治疗以恢复内皮糖萼并对抗促动脉粥样硬化内皮功能障碍	Mitra, R.	PDF	N/A	Co-Therapy with S1P and Heparan Sulfate Derivatives to Restore Endothelial Glycocalyx and Combat Pro-Atherosclerotic Endothelial Dysfunction
细胞类型特异性表观遗传流行病学研究设计与分析指南。	Walker, E. M.	PDF	N/A	Guidance for the design and analysis of cell-type specific epigenetic epidemiology studies.
T细胞受体-表位预测器的基准测试与ePytope-TCR	Drost, F.	PDF	N/A	Benchmarking of T-Cell Receptor - Epitope Predictors with ePytope-TCR
单细胞组学的无监督深度解耦表示	Moinfar, A. A.	PDF	N/A	Unsupervised Deep Disentangled Representation of Single-Cell Omics
sCellST：一种基于多实例学习的方法，用于利用空间转录组学从H&E图像预测单细胞基因表达	Chadoutaud, L.	PDF	N/A	sCellST: a Multiple Instance Learning approach to predict single-cell gene expression from H&E images using spatial transcriptomics
RNA异构体：在Python中快速渲染RNA异构体结构与表达的交互式可视化	Heberle, B. A.	PDF	N/A	RNApysoforms: Fast rendering interactive visualization of RNA isoform structure and expression in Python
TomoScore：一种用于细胞冷冻电镜质量评估的神经网络方法	Tan, X.	PDF	N/A	TomoScore: A Neural Network Approach for Quality Assessment of Cellular cryo-ET
一种环境响应型SCLA型GRAS蛋白调控了地钱（Marchantia polymorpha）的生殖策略	Hoey, D. J.	PDF	N/A	An environment-responsive SCLA-type GRAS protein controls reproductive strategy in Marchantia polymorpha
RNA甲基化在红细胞生成过程中调控应激颗粒的形成与功能	GUNAGE, R. D.	PDF	N/A	RNA methylation controls stress granule formation and function during erythropoiesis
丛枝菌根真菌对长期缺乏和N、P、K不平衡的强烈家庭和公会特异性响应	Jenab, K.	PDF	N/A	Strong family- and guild-specific responses of arbuscular mycorrhizal fungi to long-term deficiencies and imbalances of N, P and K
活酵母及其代谢产物对熊蜂微群落发育的影响	Rutkowski, D.	PDF	N/A	Effects of live yeasts and their metabolic products on bumble bee microcolony development
糖原吞噬是一种古老的两侧对称动物途径，通过STBD1结构进化支持代谢适应。	Ren, L.	PDF	N/A	Glycophagy is an ancient bilaterian pathway supporting metabolic adaptation through STBD1 structural evolution
研究交配系统对秀丽隐杆线虫抗药性进化的影响	Trubenova, B.	PDF	N/A	Investigating the consequences of the mating system for drug resistance evolution in C. elegans
IL-10通过表观遗传机制靶向IRFs以抑制IFN和炎症反应基因	Mishra, B.	PDF	N/A	IL-10 Targets IRFs to Suppress IFN and Inflammatory Response Genes by Epigenetic Mechanisms
系统筛选增强环状RNA翻译的RNA结合蛋白	Lu, Q.	PDF	N/A	Systematic screen of RNA binding proteins that enhance circular RNA translation
动物种群的随机子样本可以揭示社会性的内在差异，这对生态学、保护和疾病传播具有重要意义。	Conteddu, K.	PDF	N/A	Random subsamples of animal populations can reveal intrinsic differences in sociality with key implications in ecology, conservation and disease transmission
可解释且稳健的机器学习用于探索和分类声景数据	Omprakash, A.	PDF	N/A	Interpretable and Robust Machine Learning for Exploring and Classifying Soundscape Data
更好的抗体互补决定区设计先验分布	Wu, J.	PDF	N/A	Better Prior Distribution for Antibody Complementarity-Determining Regions Design
脂质诱导的α-突触核蛋白聚集的全局动力学模型及其通过小分子抑制的研究	Stevenson, A.	PDF	N/A	Global kinetic model of lipid-induced alpha-synuclein aggregation and its inhibition by small molecules
DeFrND：使用设计膜支架肽的无洗涤剂重构为天然纳米盘	Ren, Q.	PDF	N/A	DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides
乳腺癌细胞中CD14的异常表达与不良预后相关。	Katayama, H.	PDF	N/A	Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
Adducins 在新生皮层神经发生过程中调节神经前体细胞的形态和命运	Ossola, C.	PDF	N/A	Adducins regulate morphology and fate of neural progenitors during neocortical neurogenesis
斑马鱼嗅上皮中的成对和单独离子细胞	Peloggia, J.	PDF	N/A	Paired and solitary ionocytes in the zebrafish olfactory epithelium
BLAKOR对BNST的输入调控社会压力加剧的酒精摄入	Maiya, R.	PDF	N/A	BLAKOR inputs to the BNST regulate social stress-escalated alcohol consumption
CA2锥体细胞和表达Parvalbumin的细胞上的神经周网对海马依赖性记忆的调节作用不同。	Alexander, G. M.	PDF	N/A	Perineuronal nets on CA2 pyramidal cells and parvalbumin-expressing cells differentially regulate hippocampal dependent memory
使用荧光图像中的非均匀背景减除法进行即时早期基因表达神经元的自动细胞检测	Osanai, H.	PDF	N/A	Automated cell detection for immediate early gene-expressing neurons using inhomogeneous background subtraction in fluorescent images
Ccp1的耗竭破坏了海马区小清蛋白中间神经元的网络整合	Le Bail, R.	PDF	N/A	Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons
青春期服用激素避孕药与ABCD研究中皮质脑测量结果的关系	Heller, C.	PDF	N/A	Hormonal contraceptive intake during adolescence and cortical brain measures in the ABCD Study
皮质在动作停止中的注意定向和反应取消中的贡献	Kemp, S. A.	PDF	N/A	Cortical contributions to attentional orienting and response cancellation in action stopping
周围神经损伤后，施万细胞调控轴突球体	Hunter-Chang, S.	PDF	N/A	Axonal spheroids are regulated by Schwann cells after peripheral nerve injury
卷积神经网络模型描述了听觉皮层中局部电路的编码子空间	Wingert, J. C.	PDF	N/A	Convolutional neural network models describe the encoding subspace of local circuits in auditory cortex
应用RID-Rihaczek相位同步方法于静息状态脑电图：同时预测视空间追踪、语言交流、执行功能、神经认知健康及智力	Miyatsu, T.	PDF	N/A	RID-Rihaczek Phase Synchrony Method Applied to Resting-State EEG: Simultaneous prediction of visuospatial tracking, verbal communication, executive function, neuro-cognitive health, and intelligence
病理性tau改变头部方向信号并导致空间定向障碍	Jiang, S.	PDF	N/A	Pathological tau alters head direction signaling and induces spatial disorientation
心理任务引起大脑皮层和脊髓中振荡的共同调节	Ofner, P.	PDF	N/A	Mental Tasks Induce Common Modulations of Oscillations in Cortex and Spinal Cord
突然的感觉事件会在小鼠新皮层的各层中引发与感觉模式无关的反应	Benusiglio, D.	PDF	N/A	Sudden sensory events trigger modality-independent responses across layers in the mouse neocortex
供体胚胎干细胞通过拥挤和FGF4信号传导，在8细胞阶段嵌合体中阻碍宿主外胚层细胞的特化。	Strawbridge, S. E.	PDF	N/A	Donor embryonic stem cells impede host epiblast specification in 8-cell stage chimeras by crowding and FGF4 signalling
在胚胎神经发生过程中线粒体分配不均	Bunel, B.	PDF	N/A	Uneven mitochondrial segregation during embryonic neurogenesis
时空调控的母源性RNA在小鱼胚胎发生中的关键作用	Kushawah, G.	PDF	N/A	Critical role of Spatio-Temporally Regulated Maternal RNAs in Zebrafish Embryogenesis
RBPMS与RBPMS2协同作用以保护心脏剪接	Wu, T.	PDF	N/A	RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing
表皮PRMT5的丧失导致非典型基底角质形成细胞样细胞群的出现及皮肤分层缺陷	Recka, N. M.	PDF	N/A	Epidermal loss of PRMT5 leads to the emergence of an atypical basal keratinocyte-like cell population and defective skin stratification
BumbleBox：一个用于量化熊蜂群落行为的开源平台	Easton-Calabria, A. C.	PDF	N/A	The BumbleBox: An open-source platform for quantifying behavior in bumblebee colonies
尾标系统：利用ArUco标记在复杂环境中长期追踪多只小鼠。	Coulombe, V.	PDF	N/A	The Tailtag System: Tracking Multiple Mice in a Complex Environment Over a Prolonged Period Using ArUco Markers.
滤泡性Bcl6反应性与COVID-19中独特的免疫景观和空间转录组相关	Brenna, C.	PDF	N/A	Follicular Bcl6 reactivity is associated with a unique immune landscape and spatial transcriptome in COVID-19
留尼汪岛白纹伊蚊和致倦库蚊病毒群落的对比研究	Francois, S.	PDF	N/A	Contrasted viral communities between Aedes albopictus and Culex quinquesfasciatus in La Reunion Island
甲烷氧化菌Ca. Methanoperedens在混层湖Cadagno沉积物中的甲烷氧化适应性及其与硫酸盐还原菌的相互作用	Echeveste Medrano, M. J.	PDF	N/A	Methanotrophic flexibility of Ca. Methanoperedens and its interactions with sulfate-1 reducing bacteria in the sediment of meromictic Lake Cadagno
SARS-CoV-2轻度疾病后的谱系特异性中和抗体。疫苗接种的免疫增强效果	Davina-Nunez, C.	PDF	N/A	Lineage-specific neutralising antibodies after SARS-CoV-2 mild disease. Immune boosting effect of vaccination
可溶性电子穿梭体对微生物铁还原和产甲烷的影响	Thapa, B. S.	PDF	N/A	Effects of Soluble Electron Shuttles on Microbial Iron Reduction and Methanogenesis
开发一种新的N-端组学方法以研究金黄色葡萄球菌V8蛋白酶在人中性粒细胞中的病原降解组	Mustor, E. M.	PDF	N/A	Development of a New N-Terminomic Method to Study the Pathodegradome of the Staphylococcus aureus V8 Protease in Human Neutrophils
弓形虫感染神经元会改变细胞外囊泡的产生和内容物，进而改变星形胶质细胞的表型，并导致感染脑中GLT-1的丢失。	Tabaie, E. Z.	PDF	N/A	Toxoplasma gondii infection of neurons alters the production and content of extracellular vesicles altering astrocyte phenotype and contributing to the loss of GLT-1 in the infected brain
淡水厌氧甲烷氧化古菌暴露于硫化物时的生理应激反应	Echeveste Medrano, M. J.	PDF	N/A	Physiological stress response to sulfide exposure of freshwater anaerobic methanotrophic archaea
TlpD胞内化学感受器的C端促进极性定位与功能	Lopez-Magana, R.	PDF	N/A	The C-terminus of the TlpD cytoplasmic chemoreceptor promotes polar localization and function
流感病毒通过削弱中性粒细胞介导的通过胶囊受体捕获细菌的能力，增强了细菌在肺部的生长。	Fang, Y.	PDF	N/A	Influenza Virus Enhances Bacterial Growth in the Lungs through Weakening Capsule Receptor-Mediated Bacterial Capture by Neutrophils
SARS-CoV-2 JN.1揭示了其致病性减弱和空气传播的特性。	Liu, R.	PDF	N/A	SARS-CoV-2 JN.1 reveals attenuated pathogenicity and airborne transmission
南非2024年猴痘分子流行病学初步报告	Featherston, J.	PDF	N/A	Preliminary report on the molecular epidemiology of mpox, South Africa 2024
基于捕获离子迁移技术的空间蛋白质组学与MALDI MS/MS成像：多重化和空间肽鉴定的初步观察	Li, M. J.	PDF	N/A	Spatial Proteomics by Trapped Ion Mobility supported MALDI MS/MS Imaging: A First Glance into Multiplexed and Spatial Peptide Identification
通过稳定性/溶解度改变探索组合疗法的作用机制：推进AML治疗	Gholizadeh, E.	PDF	N/A	Exploring Mechanisms of Action in Combinatorial Therapy through Stability/Solubility Alterations: Advancing AML Treatment
生化、结构及单分子技术对LIG1活性位点突变体的表征表明，F635和F872残基在确保准确连接过程中起关键作用。	Kalaycioglu, M.	PDF	N/A	Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation
优化生物液体和细胞外囊泡的脂质组学分析工作流程：采用集成液相色谱-串联质谱方法	Vilela, A. F. L.	PDF	N/A	Optimizing Lipidomics Analysis Workflows for Biological Fluids and Extracellular Vesicles with Integrated Liquid Chromatography Tandem Mass Spectrometry Approaches
DNA StairLoop：在基于DNA的数据存储中实现高纠错和并行处理能力	Yan, Z.	PDF	N/A	DNA StairLoop: Achieving High Error-correcting and Parallel-processing Capabilities in DNA-based Data Storage
利用分裂重组酶实现复杂的视神经空间模式化	Kinstlinger, I. S.	PDF	N/A	Complex optogenetic spatial patterning with split recombinase
细胞生长周期中重组酶活性的表征	Macia, J.	PDF	N/A	CHARACTERIZATION OF RECOMBINASE ACTIVITY ACROSS CELLULAR GROWTH PHASES
微生物合作伙伴（MiPner）分析	Bennetzen, J. L.	PDF	N/A	Microbial Partner (MiPner) Analysis
Hsp20的细胞月光化功能指导了Ustilago maydis的形态和致病性发展	Mitra, A.	PDF	N/A	Cellular moonlighting function of Hsp20 directs morphological and pathogenic development in Ustilago maydis
巴基斯坦托巴·泰克辛地区后院鸽子、鸭子和鸡中禽流感的流行率及风险因素	Shakeel, I.	PDF	N/A	Prevalence and risk factors for avian influenza in backyard pigeons, ducks, and chickens in District Toba Tek Singh Pakistan
增强和验证基于云的结核杆菌遗传处理平台对抗生素耐药性预测性能	Westhead, J.	PDF	N/A	Enhancement and validation of the antibiotic resistance prediction performance of a cloud-based genetics processing platform for Mycobacteria
通过AlsE利用替代甜味剂D-阿洛酮糖的肠道微生物群	Ndjite, G. M.	PDF	N/A	Gut Microbial Utilization of the Alternative Sweetener, D-Allulose, via AlsE
评估在实际相关条件下，传统和可持续水泥基材料制成的表面上大肠杆菌的存活与去除情况	Anderson, C. E.	PDF	N/A	Evaluating the Survival and Removal of Escherichia coli from Surfaces Made with Traditional and Sustainable Cement-Based Materials in Field-Relevant Conditions
一种多价适配机制驱动蛋白酶体的核输入	Brunner, H. L.	PDF	N/A	A multivalent adaptor mechanism drives the nuclear import of proteasomes
神经肽在切叶蚁Atta cephalotes的劳动分工中起着特化和重编程的作用。	Gilbert, M. B.	PDF	N/A	Neuropeptides specify and reprogram division of labor in the leafcutter ant Atta cephalotes
优化牛细胞基因编辑：Cas9变体与CRISPR递送方法的比较研究	Du, X.	PDF	N/A	Optimizing Genome Editing in Bovine Cells: A Comparative Study of Cas9 Variants and CRISPR Delivery Methods
KDM5C是一种性别偏向的制动器，抑制了体细胞谱系中生殖系基因表达程序的激活。	Bonefas, K. M.	PDF	N/A	KDM5C is a sex-biased brake against germline gene expression programs in somatic lineages
一种机器学习分类器，用于识别和优先处理与心脏发育相关的基因	Kabir, M.	PDF	N/A	A Machine Learning Classifier to Identify and Prioritise Genes Associated with Cardiac Development
小脑-前额叶连接预测精神病谱系中阴性症状的严重程度	Yarrell, S. A.	PDF	N/A	Cerebellar-Prefrontal Connectivity Predicts Negative Symptom Severity Across the Psychosis Spectrum
TRPV4通道有助于主动脉根部硬化和动脉粥样硬化病变的发展。	Rahaman, S. G.	PDF	N/A	TRPV4 channel contributes to aortic root stiffening and atherosclerotic lesion development
# BioRxiv 2024-11-07 Papers

标题	作者	PDF链接	代码仓库	Title
后鼻皮层中的神经元在视觉双条件辨别过程中编码非空间背景信息。	Heimer-McGinn, V. R.	PDF	N/A	Neurons in the postrhinal cortex encode nonspatial context during visual biconditional discrimination
利用极值统计学将精神病理学重新概念化为偏离规范参考模型的极端偏差	Fraza, C. J.	PDF	N/A	Using extreme value statistics to reconceptualize psychopathology as extreme deviations from a normative reference model
人类细胞中以启动子为中心的相互作用的全基因组核小体分辨率图谱证实了增强子-启动子环路模型。	Golov, A. K.	PDF	N/A	A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model
多感官整合增强了Mauthner细胞的视听反应	Otero Coronel, S.	PDF	N/A	Multisensory integration enhances audiovisual responses in the Mauthner cell
多研究fMRI展望在停止信号范式中的皮层下BOLD反应	Isherwood, S. J. S.	PDF	N/A	Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm
栖息地结构复杂性通过减轻食人行为，增加了米氏野鲮鱼的年龄阶梯共存和种群增长率。	Edeline, E.	PDF	N/A	Habitat structural complexity increases age-class coexistence and population growth rate through relaxed cannibalism in medaka fish
极性交替结合化学和机械信号，驱动组织形态发生	Osterfield, M.	PDF	N/A	Alternating polarity integrates chemical and mechanical cues to drive tissue morphogenesis
篮蛤（Clinocardium nuttallii）中存在多条可传播的肿瘤谱系，并反复发生线粒体DNA的水平转移	Yonemitsu, M. A.	PDF	N/A	Multiple lineages of transmissible neoplasia in the basket cockle (Clinocardium nuttallii) with repeated horizontal transfer of mitochondrial DNA
驱动幼年斑马鱼浦肯野细胞紧张性放电的离子电导	Jadhav, M. P.	PDF	N/A	Ionic conductances driving tonic firing in Purkinje neurons of larval zebrafish
乳腺癌细胞以依赖MRTF的旁分泌方式促进破骨细胞分化	Chawla, P.	PDF	N/A	Breast cancer cells promote osteoclast differentiation in an MRTF-dependent paracrine manner
NRPS基因赋予新型枯草芽孢杆菌和类芽孢杆菌菌株抗真菌活性，并在植物病原体存在下以菌株特异性的方式改变其表达。	Vasilchenko, N.	PDF	N/A	NRPS genes provide antifungal activity to new Bacillus and Paenibacillus strains and change their expression in the presence of phytopathogens in a strain-specific manner
铜绿假单胞菌极性鞭毛组装的时空和数量调控	Pulido-Sanchez, M.	PDF	N/A	Spatial, temporal and numerical regulation of polar flagella assembly in Pseudomonas putida
单一的计算目标驱动着视觉皮层中流的专业化	Finzi, D.	PDF	N/A	A single computational objective drives specialization of streams in visual cortex
CtBP的破坏调控了小鼠胚胎干细胞中依赖和不依赖DUX的2细胞样状态的遗传程序	Sugiyama, K.	PDF	N/A	The disruption of CtBP regulates DUX-dependent and -independent genetic program for the 2-cell-like state in murine embryonic stem cells
发现高吞吐量扰动下的根因基因	Strobl, E. V.	PDF	N/A	Discovering Root Causal Genes with High Throughput Perturbations
矛盾中的导航：鼠伤寒沙门氏菌对冲突效应刺激的趋化反应	Franco, K. M.	PDF	N/A	Navigating contradictions: Salmonella Typhimurium chemotactic responses to conflicting effector stimuli
利用表观基因组数据在农场动物中注释和评估调控区域的功能变异	Ma, R.	PDF	N/A	Annotation and assessment of functional variants in regulatory regions using epigenomic data in farm animals
头足类性别的决定及其古老的进化起源	Coffing, G. C.	PDF	N/A	Cephalopod Sex Determination and its Ancient Evolutionary Origin
单细胞中基因表达与染色质可及性的灵活且高通量同时分析	Soltys, V.	PDF	N/A	Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells
外代谢物的季节性模式取决于寡营养海洋中的微生物功能	McParland, E. L.	PDF	N/A	Seasonal patterns of exometabolites depend on microbial functions in the oligotrophic ocean
跨物种感知证据积累研究框架	Chakravarty, S.	PDF	N/A	A cross-species framework for investigating perceptual evidence accumulation
葡聚糖硫酸钠诱导的肠道炎症及其全身效应的空间映射	Adams, L.	PDF	N/A	Spatial mapping of dextran sodium sulphate-induced intestinal inflammation and its systemic effects
一项多学科的玉米-豆类间作田间调查突显了振兴传统农业系统的关键考量。	Vazeux-Blumental, N.	PDF	N/A	A multidisciplinary on-farm survey of maize-bean intercropping highlights key considerations for reviving traditional agricultural systems.
新型酿酒酵母共生体生态学研究发酵模型设计	Pourcelot, E.	PDF	N/A	Design of a new model yeast consortium for ecological studies of enological fermentation
表皮胶原蛋白减少驱动感觉神经元衰老的特定方面	Krishna, M.	PDF	N/A	Epidermal Collagen Reduction Drives Selective Aspects of Aging in Sensory Neurons
带标签的分子生物学并行最大公共子图	Agbeto, W.	PDF	N/A	Parallel maximal common subgraphs with labels for molecular biology
祁连山高山草甸多年冻土融化梯度上表层土壤细菌和微真核生物的组成变化及共现模式	Wang, Z.	PDF	N/A	Compositional Shifts and Co-occurrence Patterns of Topsoil Bacteria and Micro-Eukaryotes Across a Permafrost Thaw Gradient in Alpine Meadows of the Qilian Mountains, China
氧化型低密度脂蛋白通过AT1-LOX1受体复合物增强血管紧张素II诱导的Gq激活：对肾功能障碍的启示	Ihara, J.	PDF	N/A	Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction
基于全脑细胞c-Fos表达成像的精神药物分类	Aboharb, F.	PDF	N/A	Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression
探索进化以揭示蛋白质突变稳定性的见解	Hermans, P.	PDF	N/A	Exploring evolution to uncover insights into protein mutational stability
与生物入侵过程中的适应性进化相关的花序展示的纬度梯度变化	Akbar, M.	PDF	N/A	Latitudinal clines in floral display associated with adaptive evolution during a biological invasion
个性化计算模型以构建医疗数字孪生	Knapp, A. C.	PDF	N/A	Personalizing computational models to construct medical digital twins
揭示转座子编码的Cascade-TniQ复合物中的Cas8动态与调控	Patel, A. C.	PDF	N/A	Unveiling Cas8 Dynamics and Regulation within a transposon-encoded Cascade-TniQ Complex
在斑马鱼中进行尖锐的分析，作为快速功能筛选脆性骨病致病基因的工具	Debaenst, S.	PDF	N/A	Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility
将选择与种群动态联系起来：单细胞生物主动死亡实验进化的研究	Zeballos, N.	PDF	N/A	Linking selection to demography in experimental evolution of active death in a unicellular organism
大肠杆菌表观转录组直接RNA测序揭示了热应激下的变化	Riquelme-Barrios, S.	PDF	N/A	Direct RNA sequencing of the Escherichia coli epitranscriptome uncovers alterations under heat stress
人口连接场建模揭示了胎儿人脑中原始视网膜拓扑视觉皮层组织	Yoo, S.-H.	PDF	N/A	Population connective field modeling reveals proto-retinotopic visual cortex organization in the prenatal human brain
通过CDK12/7/9降解诱导急性BRCAness并阻断AR信号传导，增强前列腺癌对PARP抑制剂的敏感性	Gui, F.	PDF	N/A	Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
早期和延迟的STAT1依赖性反应驱动脾脏巨噬细胞的局部训练免疫	Solomon, A.	PDF	N/A	Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen
外毛细胞搅动耳蜗内的液体。	Lee, C.	PDF	N/A	Outer hair cells stir cochlear fluids
在学习过程中，下边缘皮质神经元集群编码减弱了恐惧泛化表达	Subramanian, R.	PDF	N/A	An Infralimbic Cortex Neuronal Ensemble Encoded During Learning Attenuates Fear Generalization Expression
使用生物物理模型理解多电极视网膜上刺激的响应	Vilkhu, R. S.	PDF	N/A	Understanding responses to multi-electrode epiretinal stimulation using a biophysical model
致癌代谢物D-2-羟基戊二酸在IDH突变型胶质瘤中促进控制小胶质细胞激活的谱系特异性增强子的DNA高甲基化。	Laurenge, A.	PDF	N/A	The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas
乙醇通过限制蒸腾作用减少葡萄藤的水分消耗。	Ait Kaci, N.	PDF	N/A	Ethanol reduces grapevine water consumption by limiting transpiration
利用非扩散性邻近标记系统在活细胞和生物体内鉴定目标蛋白	Sun, Y.	PDF	N/A	Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
双壳纲基因组多样性的起源与功能意义	Liu, S.	PDF	N/A	The origins and functional significance of bivalve genome diversity
经颅电刺激中的前庭参与：身体摇晃作为无意刺激的标志	Laakso, I.	PDF	N/A	Vestibular involvement in transcranial electrical stimulation: body sway as a marker of unintended stimulation
金黄色葡萄球菌噬菌体phi812的细胞附着与尾部收缩	Binovsky, J.	PDF	N/A	Cell attachment and tail contraction of S. aureus phage phi812
芳香烃受体在平滑肌细胞中保护免受二噁英诱导的动脉粥样硬化不良重塑的影响	Qin, G.	PDF	N/A	Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis
组织驻留记忆CD4+ T细胞的维持依赖于特定部位的自我更新水平以及来自前体的替代。	Chandler, J.	PDF	N/A	Tissue resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and replacement from precursors
大麻烟雾和口服Δ9THC能增强老年受试者的工作记忆，但对年轻成年受试者则不然。	Zequeira, S.	PDF	N/A	Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects
ExEnDiff：一种实验引导的扩散模型，用于蛋白质构象集合生成	Liu, Y.	PDF	N/A	ExEnDiff: An Experiment-guided Diffusion model for protein conformational Ensemble generation
神经调节对沿单一模式-跨模式梯度传播的脑波的影响	Maki-Marttunen, V.	PDF	N/A	Neuromodulatory influences on propagation of brain waves along the unimodal-transmodal gradient
利用单细胞RNA测序生成稳健的微胶质细胞衰老时钟	Stanley, N.	PDF	N/A	Leveraging Single-Cell RNA-Seq to Generate Robust Microglia Aging Clocks
pLM-DBPs：利用蛋白质语言模型嵌入增强植物中DNA结合蛋白预测	Pokharel, S.	PDF	N/A	pLM-DBPs: Enhanced DNA-Binding Protein Prediction in Plants Using Embeddings From Protein Language Models
有丝分裂后依赖PP2A-Ankle2的核重构机制	Li, J.	PDF	N/A	Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis
通过超快速生物过程减轻一氧化二氮排放，实现高浓度N2O的去除	Maeda, R.	PDF	N/A	Mitigating nitrous oxide emission by an ultra-fast bioprocess enabling the removal of high concentration N2O
查尔酮异构酶的自然变异定义了一个主要位点，控制着黑杨种群间生长变异	Durufle, H.	PDF	N/A	Natural variation in chalcone isomerase defines a major locus controlling growth variation between Populus nigra populations
生物医学数据的AI准备度：Bridge2AI的建议	Clark, T.	PDF	N/A	AI-readiness for Biomedical Data: Bridge2AI Recommendations
中剂量照射损害长期造血干细胞功能及对细胞毒性压力的造血恢复能力	Zhang, Q.	PDF	N/A	Medium-dose irradiation impairs long-term hematopoietic stem cell functionality and hematopoietic recovery to cytotoxic stress
增强型Nme2Cas9和Nme2SmuCas9核酸酶及碱基编辑器的合理设计	Bamidele, N.	PDF	N/A	Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors
开发一种用于在聚球藻PCC 6803中靶向基因上调的CRISPR激活系统	Bourgade, B.	PDF	N/A	Development of a CRISPR activation system for targeted gene upregulation in Synechocystis sp. PCC 6803
简化胎鼠影像中的不对称量化：基于专家指导的半自动化流程	Rolfe, S. M.	PDF	N/A	Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance
BC-Design：一种高度准确的逆蛋白质折叠生物化学感知框架	Tang, X.	PDF	N/A	BC-Design: A Biochemistry-Aware Framework for Highly Accurate Inverse Protein Folding
从父母谈判策略的演变中出现的替代后代抚养模式	Zheng, J.	PDF	N/A	Emergence of alternative offspring care patterns from the evolution of parental negotiation strategies
通过X射线晶体学鉴定出的电压门控钠通道中对挥发性麻醉剂具有功能重要性的结合位点	Hollingworth, D.	PDF	N/A	Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography
维生素B12通过改善丙酸分解和一碳循环代谢途径，部分挽救了秀丽隐杆线虫Ephrin突变体胚胎细胞迁移缺陷。	Ganjawala, T. H.	PDF	N/A	Vitamin B12 partially rescues embryonic cell migration defects in C. elegans ephrin mutants by improving both propionic acid breakdown and one-carbon cycle metabolic pathways
淋巴细胞减少促使T细胞耗竭在免疫缺陷型STING功能获得性小鼠中	Freytag, D.	PDF	N/A	Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice
Vcfexpress：灵活、快速的用户表达式，用于过滤和格式化VCF文件	Pedersen, B. S.	PDF	N/A	Vcfexpress: flexible, rapid user-expressions to filter and format VCFs
一项跨研究的转录性心力衰竭患者图谱定义了心脏重塑中保守的多细胞协调机制。	Lanzer, J. D.	PDF	N/A	A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling
随着时间的推移，音乐中概念形成的中枢机制	Bonetti, L.	PDF	N/A	The neural mechanisms of concept formation over time in music
非重组基因组中因净化选择引起的Hill-Robertson干扰模型	Becher, H.	PDF	N/A	A model of Hill-Robertson interference caused by purifying selection in a non-recombining genome
使用EquiRep从含有错误的高错误率序列中准确检测串联重复序列	Song, Z.	PDF	N/A	Accurate Detection of Tandem Repeats from Error-Prone Sequences with EquiRep
Metapredict能够在生命之树的各个分支上实现准确的失序预测。	Lotthammer, J. M.	PDF	N/A	Metapredict enables accurate disorder prediction across the Tree of Life
自闭症谱系障碍中的从头结构变异破坏了神经元基因的远端调控相互作用	Gjoni, K.	PDF	N/A	De novo structural variants in autism spectrum disorder disrupt distal regulatory interactions of neuronal genes
可重复处理的TCGA调控网络	Fanfani, V.	PDF	N/A	Reproducible processing of TCGA regulatory networks
超-k-mers：高效的流式k-mers表示	Martayan, I.	PDF	N/A	Hyper-k-mers: efficient streaming k-mers representation
解读功能性分化初始T细胞亚群背后的基因调控程序	Zhu, H.	PDF	N/A	Deciphering gene regulatory programs underlying functionally divergent naive T cell subsets
睡眠期间Sigma频段功率的慢波波动：与觉醒标志及记忆再激活在发育过程中的关联	Dimitriades, M. E.	PDF	N/A	The Infraslow Fluctuation of Sigma Power During Sleep: Links to Markers of Arousal and Memory Reactivation Across Development
基于单个神经元活动的前额叶皮层图谱	Le Merre, P.	PDF	N/A	A Prefrontal Cortex Map based on Single Neuron Activity
小鼠情景记忆样记忆发展的敏感期	Ramsaran, A. I.	PDF	N/A	A sensitive period for the development of episodic-like memory in mice
"小动作，大影响：早期短暂运动训练对小鼠神经肌肉发育的影响"	Quilgars, C.	PDF	N/A	When Little Means a Lot: Impact of a Brief Early-life Motor Training on Mouse Neuromuscular Development.
调节注意力网络中依赖学习的可塑性	Conto', F.	PDF	N/A	Modulation of learning-dependent plasticity in the attention network
欧洲西尼罗河病毒传播的生物气候模型，特别关注乌克兰	Mezhzherin, S.	PDF	N/A	Bioclimatic modelling of the spread of the West Nile virus in Europe, with a special focus on Ukraine
社区保守性在微生物门类和环境中普遍存在。	Malfertheiner, L.	PDF	N/A	Community conservatism is widespread throughout microbial phyla and environments
现代人类生殖基因中的古适应性渗入	Kendall, C. J. R.	PDF	N/A	Archaic Adaptive Introgression in Modern Human Reproductive Genes
基因重复后表达变异性的增加有助于基因的保留	Cai, H.	PDF	N/A	Expression variability following gene duplication facilitates gene retention
干细胞性预测模型揭示了胶质瘤的侵袭性及治疗靶点	Simoes, R. d. L. S.	PDF	N/A	Stemness prediction models reveal glioma aggressiveness and therapeutic targets in gliomas
高质量的大规模开花沙漠植物Cistanthe longiscapa的基因组及其与干旱和生命史相关的光合作用行为	Chomentowska, A.	PDF	N/A	A high-quality genome of the mass-blooming desert plant Cistanthe longiscapa and its photosynthetic behavior related to drought and life history
人类小脑和腹侧被盖区在习得性恐惧消退过程中相互作用	Nio, E.	PDF	N/A	Human cerebellum and ventral tegmental area interact during extinction of learned fear
TIA1介导了小胶质细胞和巨噬细胞对Tau病的不同炎症反应	Webber, C. J.	PDF	N/A	TIA1 Mediates Divergent Inflammatory Responses to Tauopathy in Microglia and Macrophages
源自汉坦病毒的肽段能够稳定HLA-E，从而解除CD56dimNKG2A+ NK细胞的抑制作用。	Manling, X.	PDF	N/A	Hantaan virus-derived peptides that stabilize HLA-E could abrogate inhibition of CD56dimNKG2A+ NK cells
鹦鹉发声生产学习的演变	Krasheninnikova, A.	PDF	N/A	Evolution of vocal production learning in parrots
社会性如何影响繁殖者对恶劣热环境的适应性反应？埋葬甲虫的一项实验	Ma, D.	PDF	N/A	Sociality shapes the adaptive response of breeders to harsh thermal environments? An experiment in a burying beetle
禾本科姐妹基因组揭示了草类出现前的关键代谢创新	Takeda-Kimura, Y.	PDF	N/A	Genomes of Poaceae sisters reveal key metabolic innovations preceding the emergence of grasses
PLM-interact：扩展蛋白质语言模型以预测蛋白质-蛋白质相互作用	Liu, D.	PDF	N/A	PLM-interact: extending protein language models to predict protein-protein interactions
GenomicSign：一种用于发现目标基因组序列的独特、特异且可扩增的特征的计算方法	Kumar S, P.	PDF	N/A	GenomicSign: A computational method to discover unique, specific, and amplifiable signatures of target genomic sequences
湿度感应受损通过阻止水分平衡，降低了蜱的存活率。	Uhran, M. R.	PDF	N/A	Impaired humidity sensing reduces tick survival by preventing water homeostasis
从单次MRI估计的终身脑萎缩：测量特征和全基因组关联	Fürtjes, A. E.	PDF	N/A	Lifetime brain atrophy estimated from a single MRI: measurement characteristics and genome-wide correlates
NOLC1通过抑制p53介导的铁死亡在胃癌中抑制免疫化疗	Zhao, S.	PDF	N/A	NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer
差异性KEAP1/NRF2介导的信号传导扩大了氧化还原靶向药物在SCLC治疗中的治疗窗口	Samarin, J.	PDF	N/A	Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy
在使用Parsortix系统观察胰腺癌细胞系时发现的偏差	Vandenbussche, N.	PDF	N/A	Biases in the Parsortix system observed with pancreatic cancer cell lines
从小鼠成纤维细胞诱导生成具有致癌性的多能干细胞	Shabrish, S.	PDF	N/A	Induction of pluripotent oncogenic stem cells from mouse fibroblasts
抑制p38-MK2通路可增强微管抑制剂在乳腺癌细胞中的疗效	Chen, Y.-C.	PDF	N/A	Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells
差异表达的生长因子和细胞因子驱动可传播癌症的表型变化	Maskell, K. G.	PDF	N/A	Differentially expressed growth factors and cytokines drive phenotypic changes in transmissible cancers
最大化减数分裂交叉率揭示了交叉潜能图谱	Jing, J.	PDF	N/A	Maximizing meiotic crossover rate reveals the map of Crossover Potential
来自不动杆菌属的OXA β-内酰胺酶是膜结合的，并被分泌到外膜囊泡中。	Capodimonte, L.	PDF	N/A	OXA beta-lactamases from Acinetobacter spp. are membrane-bound and secreted into outer membrane vesicles
抑制和更新共享资源：来自漂移扩散模型的证据	Sun, Y.	PDF	N/A	Inhibition and Updating Share Common Resources: Evidence from Drift Diffusion Model
静息态连接改变淀粉样蛋白对认知和身体功能的影响：基于网络的认知储备证据	Laurienti, P. J.	PDF	N/A	Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve
p.A53T-α-突触核蛋白诱导多能干细胞衍生的星形胶质细胞中的蛋白质稳态失调加剧了具有类Lewy病理的帕金森病模型中的神经退行性变	Paschou, C.	PDF	N/A	Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson's disease model with Lewy-like pathology
电协调重置刺激在癫痫持续状态的体内模型中诱导网络去同步化	Ehrens, D.	PDF	N/A	Electrical Coordinated Reset Stimulation Induces Network Desynchronization in an in Vivo Model of Status Epilepticus
概率编程语言中的动态因果建模	Baldy, N.	PDF	N/A	Dynamic Causal Modeling in Probabilistic Programming Languages
单目标光片显微镜可实现果蝇活体脑部的高分辨率成像。	Tassara, F. J.	PDF	N/A	Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila.
医学：神经电生理记录的运动校正	Watters, N.	PDF	N/A	MEDiCINe: Motion Correction for Neural Electrophysiology Recordings
评估使用扩散去噪概率模型生成的合成扩散磁共振成像图谱	Chattopadhyay, T.	PDF	N/A	Evaluating Synthetic Diffusion MRI Maps created with Diffusion Denoising Probabilistic Models
降低胆固醇酯转移蛋白（CETP）活性可预防阿尔茨海默病小鼠模型中的记忆衰退	Phenix, J.	PDF	N/A	Reducing CETP activity prevents memory decline in an Alzheimer's disease mouse model
奖励性和厌恶性刺激对中央杏仁核中D1型和D2型多巴胺敏感神经元产生相反的影响	Bijoch, L.	PDF	N/A	Opposing effects of rewarding and aversive stimuli on D1 and D2 types of dopamine-sensitive neurons in the central amygdala
海马体CA3亚区的空间编码受递归连接的影响	Kong, E.	PDF	N/A	Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions
SMAS：基于贝叶斯VAE的结构MRI阿尔茨海默病评分	Nemali, A.	PDF	N/A	SMAS: Structural MRI-Based AD Score using Bayesian VAE
高度社会性慈鲷下丘脑和视前区的单核转录组	Miller-Crews, I.	PDF	N/A	Single-nuclei transcriptomes in the hypothalamus and POA of a highly social cichlid
即插即用的肌电控制通过自校准的随机森林通用模型实现	Jiang, X.	PDF	N/A	Plug-and-Play Myoelectric Control via a Self-Calibrating Random Forest Common Model
轴突损伤信号受到保留的突触分支的抑制。	Smithson, L. J.	PDF	N/A	Axonal injury signaling is restrained by a spared synaptic branch
昼夜结构可塑性的超微结构相关性	Ispizua, J. I.	PDF	N/A	Ultrastructural correlates of circadian structural plasticity
全转录组小核糖体亚基图谱揭示了哺乳动物大脑中翻译起始的扫描机制	Kute, P.	PDF	N/A	Transcriptome-wide mapping of small ribosomal subunits elucidates scanning mechanisms of translation initiation in the mammalian brain
神经元群体对相位锁定刺激的响应：基于模型的预测与验证	Mirkhani, N.	PDF	N/A	Response of neuronal populations to phase-locked stimulation: model-based predictions and validation
嗅觉球追踪自由活动小鼠的呼吸节奏和位置	Sterrett, S. C.	PDF	N/A	Olfactory bulb tracks breathing rhythms and place in freely behaving mice
统一海马旁区功能：一种预测图谱方法	Bennett, L.	PDF	N/A	Unifying Subicular Function: A Predictive Map Approach
将生物性别作为主要变量可能会限制我们对精神兴奋剂活动中行为多样性（及性别差异）的理解。	Yao, G.	PDF	N/A	Employing biological sex as a primary variable can restrict our understanding of behavioral diversity (and sex differences) in psychostimulant activity.
静息状态网络是大脑的认知原子吗？任务间和静息状态下功能性脑网络的动态重构差异	Jung, J.	PDF	N/A	Are resting-state networks the brain's cognitive atoms? Differential dynamic reconfiguration of functional brain networks across tasks and at rest
通过多重CRISPR/Cas9基因编辑揭示的GABA转运体3介导的小鼠视觉皮层星形胶质细胞对群体编码的调节	Park, J.	PDF	N/A	Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
通过通信子空间测量神经群体之间的刺激信息传递	Weiss, O.	PDF	N/A	Measuring Stimulus Information Transfer Between Neural Populations through the Communication Subspace
通过静息状态下的alpha动态区分幻觉倾向维度	Honcamp, H.	PDF	N/A	Differentiating hallucination proneness dimensions through resting state alpha dynamics
一种用于增强音乐寒意体验的个性化播放列表的冷感脑机音乐接口	Kondoh, S.	PDF	N/A	A chill brain-music interface for enhancing music chills with personalized playlists
神经损伤对小鼠蓝斑功能和行为影响的性别差异	Mariscal, P.	PDF	N/A	Sex differences in the impact of nerve injury on Locus Coeruleus function and behaviour in mice
可卡因通过ΔFosB重塑了腹侧海马的基因表达和兴奋性	Eagle, A. L.	PDF	N/A	Cocaine, via ΔFosB, remodels gene expression and excitability in ventral hippocampus
个性化tDCS针对视觉运动区域V5调节平滑追踪启动	Radecke, J.-O.	PDF	N/A	Personalized tDCS targeting visual motion area V5 modulates smooth pursuit initiation
肠道微生物群调控运动诱导的激素性调节认知功能	Cintado, E.	PDF	N/A	Gut Microbiota Regulates Exercise-induced Hormetic Modulation of Cognitive Function
电刺激期间无伪影脑电图的实时时空滤波	Menrath, D.	PDF	N/A	Real-Time Spatiotemporal Filtering for Artifact-Free EEG during Electrical Neurostimulation
BMP4足以诱导尾侧组织者	Xu, P.-F.	PDF	N/A	BMP4 is sufficient to induce a caudal organizer
Numb为成年果蝇中肠干细胞自我更新提供了一种安全保障机制。	Li, M.	PDF	N/A	{-}Numb provides a fail-safe mechanism for intestinal stem cell self-renewal in adult Drosophila midgut
FVB/N小鼠亚系在新生儿阿片戒断期间的超声发声（USVs）的声学特性、音节结构和音节序列	Wingfield, K. K.	PDF	N/A	The acoustic properties, syllable structure, and syllable sequences of ultrasonic vocalizations (USVs) during neonatal opioid withdrawal in FVB/N mouse substrains
CIFR（克隆-整合-翻转-切除-重复）：用于革兰氏阴性菌基因组和通路迭代工程的工具集	Federici, F.	PDF	N/A	CIFR (Clone-Integrate-Flip-out-Repeat): a toolset for iterative genome and pathway engineering of Gram-negative bacteria
利用计算结构预测探索工程受体性能中的结构-功能关系	Corcoran, W. K.	PDF	N/A	Exploring structure-function relationships in engineered receptor performance using computational structure prediction
与摄入营养性和非营养性溶液相关的组胺的快速波动	Volcko, K. L.	PDF	N/A	Rapid fluctuations in histamine associated with intake of nutritive and non-nutritive solutions
线粒体酶GPT2的缺失导致突触谷氨酸代谢的重编程	Baytas, O.	PDF	N/A	Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism
psilocybin对前额-纹状体-丘脑回路动态连接和有效连接的长期影响	Pasquini, L.	PDF	N/A	Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic circuits
RBFOX1缺陷的纠正能够挽救亨廷顿病的错误剪接和病理	Lozano-Munoz, D.	PDF	N/A	Correction of RBFOX1 deficit rescues Huntington's disease mis-splicing and pathology
不同同义密码子替换策略对SARS-CoV-2核衣壳蛋白在埃希氏大肠杆菌中表达的影响	Bello, A. J.	PDF	N/A	Impact of different synonymous codon substitution strategies on SARS-CoV-2 nucleocapsid protein expression in Escherichia coli
单一嵌合刺突抗原诱导泛萨贝科病毒免疫	Counoupas, C.	PDF	N/A	A Single Chimeric Spike Antigen Induces Pan-Sarbecovirus Immunity
了解海洋生态系统中发现的生物聚合物如何影响噬菌体对细菌的效力	Kwack, J.	PDF	N/A	Understanding How Biopolymers Found in Marine Ecosystems Impact the Efficacy of Bacteriophages against Bacteria
通过厌氧光敏化实现产油微藻培养的阿克西尼化。	Iyer, A.	PDF	N/A	Axenisation of oleaginous microalgal cultures via anoxic photosensitisation.
在极度濒危的鸮鹦鹉（Strigops habroptilus）中，肠道外致病性大肠杆菌、粪肠球菌和格氏链球菌在渗出性泄殖腔炎的病因学中起作用的证据	French, R. K.	PDF	N/A	Evidence for a role of extraintestinal pathogenic Escherichia coli, Enterococcus faecalis and Streptococcus gallolyticus in the aetiology of exudative cloacitis in the critically endangered kakapo (Strigops habroptilus)
超粘液型肺炎克雷伯菌气溶胶持久性的比较研究	Chirichella, N.	PDF	N/A	Comparative Aerosol Persistence of Hypermucoid Klebsiella pneumoniae
膜不对称性促进鼠诺如病毒的进入和持续性肠道感染	Stewart, B. M.	PDF	N/A	Membrane asymmetry facilitates murine norovirus entry and persistent enteric infection
Mla途径促进霍乱弧菌从静止期重新扩张	Leitner, D. R.	PDF	N/A	The Mla pathway promotes Vibrio cholerae re-expansion from stationary phase
竞争策略驱动几丁质降解群落中的资源划分	Pontrelli, S.	PDF	N/A	Competition strategies driving resource partitioning in chitin degrading communities
在亲缘关系相近的物种中，细菌伸长的表型可塑性	Delaby, M.	PDF	N/A	Phenotypic plasticity in bacterial elongation among closely related species
醋酸通过在耐药细菌中引发渗透压失衡，协同增强掺钴碳量子点的杀菌效率。	Truskewycz, A.	PDF	N/A	Acetic acid induces osmotic imbalances in drug-resistant bacteria synergistically enhancing cobalt-doped carbon quantum dots bactericidal efficiency
甲萘醌可降低幽门螺杆菌中与毒力和定殖相关基因的表达。	Thompson, S.	PDF	N/A	Menadione reduces the expression of virulence- and colonisation-associated genes in Helicobacter pylori
两性霉素B增强SARS-CoV-2感染：对疾病管理的启示	Nguyen, D.	PDF	N/A	SARS-CoV-2 infection enhancement by Amphotericin B: Implications for disease management
通过基于深度学习的结构集合解码DNA连接酶活性中的蛋白质动态性	Mishra, N.	PDF	N/A	Decoding protein dynamicity in DNA ligase activity through deep learning-based structural ensembles
Rab40 GTP酶调节AMBRA1介导的转录和细胞迁移	Sampath, R.	PDF	N/A	Rab40 GTPases regulate AMBRA1-mediated transcription and cell migration
通过不同的DNA结合动力学实现TBP同源物的功能分化	Cui, J. H.	PDF	N/A	Functional divergence of TBP homologs through distinct DNA binding dynamics
依赖盐的非催化变构调节：人USP14调控的26S蛋白酶体	Zou, S.	PDF	N/A	Salt-dependent non-catalytic allostery of human USP14-regulated 26S proteasome
Rad52在DNA接合处对Rad51进行分类和堆叠，以促进同源重组。	Deveryshetty, J.	PDF	N/A	Rad52 sorts and stacks Rad51 at the DNA junction to promote homologous recombination
经过工程改造的HMGB1结构，具有串联的HMG B结构域，可促进组织再生，同时避免潜在的有害炎症或血栓形成。	Vinals Guitart, A.	PDF	N/A	Engineered HMGB1 Construct with Tandem HMG B Domains that Promotes Tissue Regeneration without Potential for Deleterious Inflammation or Thrombosis
全面的蛋白酶特异性分析	Zhu, B.	PDF	N/A	Comprehensive protease specificity profiling
植物中的遗传开关	Kassaw, T. K.	PDF	N/A	A Genetic Toggle Switch in Plants
通过交替框架插入创建重叠基因	Leonard, S. P.	PDF	N/A	Creating overlapping genes by alternate-frame insertion
粘细菌黄杆菌（Myxococcus xanthus）中分层和聚集的遗传与环境决定因素	Khan, T. T.	PDF	N/A	Genetic and Environmental Determinants of Streaming and Aggregation in Myxococcus xanthus
细菌战与毒力和抗菌药物耐药性相关	Sharp, C.	PDF	N/A	Bacterial warfare is associated with virulence and antimicrobial resistance
丝裂霉素C在伊利湖中以微囊藻为主的水华环境中，能够消除蓝藻的转录活动，且未检测到溶原性诱导现象。	Martin, R. M.	PDF	N/A	Mitomycin C eliminates cyanobacterial transcription without detectable lysogen induction in a Microcystis-dominated bloom in Lake Erie
环境变化带来的压力促使一种持续性肠道病毒被清除	Herrmann, C.	PDF	N/A	Stress from environmental change drives clearance of a persistent enteric virus
使用人源化小鼠研究ibezapolstat及其他与艰难梭菌感染相关的抗生素对微生物组的影响	Wolfe, T. M.	PDF	N/A	Microbiome impact of ibezapolstat and other Clostridioides difficile infection relevant antibiotics using humanized mice
通过控制发酵提高毕赤酵母中免疫原性脊髓灰质炎病毒类病毒颗粒的产量	Sherry, L.	PDF	N/A	Upscaling production of immunogenic poliovirus virus-like particles in Pichia Pastoris by controlled fermentation
夏威夷短尾鱿鱼生殖器官的组织结构和细菌微生境揭示了防御性共生的维度	Kamp, D.	PDF	N/A	Organ structure and bacterial microbiogeography in a reproductive organ of the Hawaiian bobtail squid reveal dimensions of a defensive symbiosis
Jade1与HBO1复合物是Oct4的空间选择性辅因子。	Wu, Y.	PDF	N/A	Jade1 and the HBO1 complex are spatial-selective cofactors of Oct4
不同营养级群体间的社会信息利用	Muniz, M.	PDF	N/A	Social information use across trophic guilds
癫痫小鼠模型中背侧和腹侧苔藓细胞的改变与失衡	Huang, C. S.	PDF	N/A	Alterations and Imbalance of Dorsal and Ventral Mossy Cells in a Mouse Model of Epilepsy
自噬压力在神经元中激活了不同的补偿性分泌途径	Palumbos, S. D.	PDF	N/A	Autophagic stress activates distinct compensatory secretory pathways in neurons
人类行为中逐次试验学习后继表征	Kahn, A. E.	PDF	N/A	Trial-by-trial learning of successor representations in human behavior
左侧弓状束的发育与阅读学习进步相关，但与数学学习无关	Roy, E.	PDF	N/A	Development of the Left Arcuate Fasciculus is Linked to Learning Gains in Reading, but not Math
互补参考框架下时间神经表征	Xu, Y.	PDF	N/A	Neural Representation of Time across Complementary Reference Frames
抗噬菌体防御中的淀粉样信号	Saupe, S. J.	PDF	N/A	Amyloid signaling in antiphage defense
FOXP基因调控小脑发育和进化中的浦肯野细胞多样性	Khouri-Farah, N.	PDF	N/A	FOXP Genes Regulate Purkinje Cell Diversity in Cerebellar Development and Evolution
# BioRxiv 2024-11-06 Papers

标题	作者	PDF链接	代码仓库	Title
脊髓兴奋性增加导致运动复杂性降低	de Graaf, M. L.	PDF	N/A	Increased spinal excitation causes decreased locomotor complexity
婴儿低频脑电皮层功率、皮层追踪和相位振幅耦合预测一年后的语言能力。	Attaheri, A.	PDF	N/A	Infant low-frequency EEG cortical power, cortical tracking and phase-amplitude coupling predicts language a year later.
在真菌发病过程中，铁死亡的一种新型线粒体调节网络	Shen, Q.	PDF	N/A	A novel mitochondrial regulon for Ferroptosis during fungal pathogenesis
一统天下？评估可持续森林管理指标对多分类群数据在生物多样性保护中的表现	Paillet, Y.	PDF	N/A	One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation
光敏素将绿藻中的蓝光感知与淀粉代谢联系起来	Yuan, Y.	PDF	N/A	Phototropin connects blue light perception to starch metabolism in green algae
逐次检测神经时间序列中的认知事件	Weindel, G.	PDF	N/A	Trial-by-trial detection of cognitive events in neural time-series
从BioModels中筛选模型：开发创建OMEX文件的工作流程	Xu, J.	PDF	N/A	Curating models from BioModels: Developing a workflow for creating OMEX files
一段涉及多个P450基因的基因组重复有助于登革热蚊子埃及伊蚊的杀虫剂抗性。	Bacot, T.	PDF	N/A	A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
将心率与自我-社交触摸区分中涉及的皮层网络动态相联系	Candia-Rivera, D.	PDF	N/A	Linking heartbeats with the cortical network dynamics involved in self-social touch distinction
ARTEM：一种用于识别RNA和DNA三级基序的方法，包括骨架排列，并举例应用于类扭结转角基序	Baulin, E. F.	PDF	N/A	ARTEM: a method for RNA and DNA tertiary motif identification with backbone permutations, and its example application to kink-turn-like motifs
使用重组脱氧核糖核酸酶I治疗抗髓过氧化物酶肾小球肾炎，通过腺相关病毒基因疗法得到增强	Cao Le, A.	PDF	N/A	Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy
空间转录组学基因表达框架	Cao, S.	PDF	N/A	A framework for gene representation on spatial transcriptomics
强迫性与适应性应对策略的肾上腺素能和巴甫洛夫基础	Chernoff, C. S.	PDF	N/A	Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies
FoldMark：通过水印技术保护蛋白质生成模型	ZHANG, Z.	PDF	N/A	FoldMark: Protecting Protein Generative Models with Watermarking
偏倚校正元分析克服小脑忽视，以完善小脑行为地形图	Magielse, N.	PDF	N/A	Bias-accounting meta-analyses overcome cerebellar neglect to refine the cerebellar behavioral topography
父母谈判策略演变中衍生出的替代后代抚养模式的出现	Zheng, J.	PDF	N/A	Emergence of alternative offspring care patterns from the evolution of parental negotiation strategies
进化上较近的转录因子参与人类细胞周期的调控	Pulver, C.	PDF	N/A	Evolutionarily recent transcription factors partake in human cell cycle regulation
调控转录因子（TF）-DNA相互作用的比较和群体基因组学分析	Joshi, M.	PDF	N/A	Comparative and population genomics analyses of the regulatory Transcription Factor (TF)-DNA interaction
多样化的祖先代表性改善了遗传不耐受度量	Han, A.	PDF	N/A	Diverse ancestral representation improves genetic intolerance metrics
单变量与多变量参考区间方法的比较	MERGEN, E. K.	PDF	N/A	COMPARISON OF UNIVARIATE AND MULTIVARIATE REFERENCE INTERVAL METHODS
用于复杂异质性单细胞数据的标记基因捕捞	Shao, Y.	PDF	N/A	Marker gene fishing for single-cell data with complex heterogeneity
未能考虑RNA数量会导致背景升高，并导致PRC2和GFP在体内结合RNA的误导性表象。	Guo, J. K.	PDF	N/A	Failing to account for RNA quantity inflates background and leads to the misleading appearance that PRC2 and GFP bind to RNA in vivo
解码肝癌预后：从多组学亚型、预后模型到单细胞验证	Wang, Y.	PDF	N/A	Decoding Liver Cancer Prognosis: From Multi-omics Subtypes, Prognostic Models to Single Cell Validation
复杂性和孟德尔性状中的多效性决定因素及其进化后果	Barbitoff, Y. A.	PDF	N/A	Functional determinants and evolutionary consequences of pleiotropy in complex and Mendelian traits
利用可扩展的方法恢复和维持人类死后视网膜的光反应，以测试退行性疾病疗法	Becker, S.	PDF	N/A	Restoring and sustaining human postmortem retinal light responses with scalable methods for testing degenerative disease therapies
酒精依赖戒断的神经标志物：来自奖励学习的启示	Komarnyckyj, M.	PDF	N/A	Neural markers of abstinence in alcohol dependence: Insights from Reward Learning
两个H3K23组蛋白甲基转移酶，SET-32和SET-21，协同作用以促进在秀丽隐杆线虫中通过核RNAi介导的跨代表观遗传继承。	Gu, S. G.	PDF	N/A	Two H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote nuclear RNAi-mediated transgenerational epigenetic inheritance in Caenorhabditis elegans
两种H3K23组蛋白甲基转移酶，SET-32和SET-21，在秀丽隐杆线虫中协同作用，促进核RNAi介导的跨代表观遗传继承。	Gu, S. G.	PDF	N/A	Two H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote nuclear RNAi-mediated transgenerational epigenetic inheritance in Caenorhabditis elegans
孕期补充益生菌对健康人群是否安全？一项针对临床前研究的系统综述	COCA, M. R.	PDF	N/A	Is Probiotic Supplementation During Pregnancy Safe for Healthy Populations? A Systematic Review of Preclinical Studies
神经元检测触发全身消化系统关闭，以应对不良食物来源	Liu, Y.	PDF	N/A	Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources
从开花期到高温耐受性：PHOTOPERIOD 1（PPD-H1）通过提高高温环境下的抗逆性和能量代谢来调控穗部结实率	Lan, T.	PDF	N/A	From Flowering Time to High Temperature Resilience: PHOTOPERIOD 1 (PPD-H1) Controls Spike Fertility through Improving Stress Resistance and Energy Metabolism under High Ambient Temperatures
陆生植物特异的H3K27甲基转移酶ATXR5和ATXR6调控植物发育及胁迫响应	Li, X.	PDF	N/A	Land plant-specific H3K27 methyltransferases ATXR5 and ATXR6 control plant development and stress responses
实时闭环反馈系统用于小鼠中尺度皮层信号与运动控制：CLoPy	Gupta, P. K.	PDF	N/A	Real-Time Closed-Loop Feedback System For Mouse Mesoscale Cortical Signal And Movement Control: CLoPy
巨噬细胞-平滑肌细胞轴通过激活EGFR途径影响大细胞性动脉炎中的血管重塑	Chevalier, K.	PDF	N/A	A macrophage-smooth muscle cell axis influences vascular remodeling through activation of the EGFR pathway in giant cell arteritis
淋巴细胞减少促使T细胞衰竭在免疫缺陷STING功能获得性小鼠中	Freytag, D.	PDF	N/A	Lymphopenia drives T cell exhaustion in immunodeficient STING gain-of-function mice
用于体外流感气溶胶暴露的气液界面模型	Seibert, B.	PDF	N/A	Air-Liquid Interface Model for Influenza Aerosol Exposure In Vitro
血液点卡上动物粪便材料的DNA提取方案	Llarena, A.-K.	PDF	N/A	DNA Extraction Protocols for Animal Fecal Material on Blood Spot Cards
通过液相色谱-串联质谱（LC-MS/MS）对mRNA中的N6-甲基腺苷和肌苷进行全球分析揭示了复杂的分布情况。	Stejskal, S.	PDF	N/A	Global Analysis by LC-MS/MS of N6-Methyladenosine and Inosine in mRNA Reveals Complex Incidence
双CRISPR干扰策略用于靶向癌细胞中非编码RNA之间的合成致死相互作用	Schlosshauer, J. J.	PDF	N/A	Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions between Non-Coding RNAs in Cancer Cells
Vcfexpress：灵活、快速的过滤和格式化VCF的用户表达式	Pedersen, B. S.	PDF	N/A	Vcfexpress: flexible, rapid user-expressions to filter and format VCFs
预测肿瘤突变负荷从超高频介电泳交叉频率	Daverat, H.	PDF	N/A	Predicting Tumor Mutational Burden from UHF-Dielectrophoresis Crossover Frequency
CD3、CD4和CD8的染色结果与亚洲乳腺癌患者的总体生存呈正相关，而PD-L1则不然。	Pan, J.-W.	PDF	N/A	CD3, CD4, and CD8 staining, but not PD-L1, are positively correlated with overall survival in Asian breast cancer
DNA甲基化是转移性肾细胞癌中靶向治疗和免疫检查点治疗反应的关键决定因素。	Jeanneret, F.	PDF	N/A	DNA methylation is a key determinant of response to targeted and immune checkpoint therapies in metastatic renal cell carcinoma
解析油菜开花时间变异的分子基础	Zhang, L.	PDF	N/A	Dissecting the molecular basis of variability for flowering time in Camelina sativa
R-Loop的调控与线粒体基因组的稳定性需要5'-3'外切核酸酶/盖帽内切核酸酶OEX1的参与。	Schatz-Daas, D.	PDF	N/A	R-Loop control and mitochondria genome stability requires the 5'-3' exonuclease/flap-endonuclease OEX1
利用大型语言模型推进植物代谢研究：扩展数据库并提取标注数据	Knapp, R.	PDF	N/A	Advancing Plant Metabolic Research By Using Large Language Models To Expand Databases And Extract Labelled Data
标注冷冻电镜断层成像体积：一项机器学习挑战	Peck, A.	PDF	N/A	Annotating CryoET Volumes: A Machine Learning Challenge
雌性蛾类将植物声学信号纳入其产卵决策中	Seltzer, R.	PDF	N/A	Female Moths Incorporate Plant Acoustic Emissions into Their Oviposition Decision
利用CFD建模描述叶轮设计对植物细胞发酵的影响	Manickavasagam, V. M.	PDF	N/A	Characterizing the effect of impeller design in plant cell fermentations using CFD modeling
磷酸酶PP2C12是LRX-RALF-FER介导的细胞壁完整性感知中的负调控因子。	Hou, X.	PDF	N/A	The phosphatase PP2C12 is a negative player in LRX-RALF-FER-mediated cell wall integrity sensing
基质利用和交叉喂养协同作用决定了微生物群对病原体入侵的抵抗力	Yang, X.	PDF	N/A	Substrate utilization and cross-feeding synergistically determine microbiome resistance to pathogen invasion
在脆性X模型中，重复扩展与由Pol θ、Rad52、Rad54l或Rad54b介导的双链断裂修复无关。	Hayward, B. E.	PDF	N/A	Repeat expansion in a Fragile X model is independent of double strand break repair mediated by Pol θ, Rad52, Rad54l or Rad54b
细胞生长的几何平衡模型	Vazquez, A.	PDF	N/A	Geometrically balanced model of cell growth
神经血管完整性与衰老中液体运输的关系：一项多模态神经影像学研究	Rowsthorn, E.	PDF	N/A	Relationships between measures of neurovascular integrity and fluid transport in aging: a multi-modal neuroimaging study
皮层生长抑素中间神经元对神经血管耦合的双向调控	Mohamed, B.	PDF	N/A	Bidirectional control of neurovascular coupling by cortical somatostatin interneurons
同时诱发的慢伽马波和快伽马波在灵长类动物初级视觉皮层中独立传播	Gautham, B. K.	PDF	N/A	Simultaneously induced slow and fast gamma waves travel independently in primate primary visual cortex
AAV载体中微RNA靶序列排列的优化显著增强了皮层小胶质细胞中转基因表达的特异性和效率	Aoki, R.	PDF	N/A	Optimization of microRNA Target Sequence Arrangement in AAV Vectors Dramatically Enhances Specificity and Efficiency of Transgene Expression in Cortical Microglia
RAB GTP酶的邻近图谱	Gaudreault St-Laurent, V.	PDF	N/A	A Proximity MAP of RAB GTPases
一种用于蓝钟虫单细胞习惯化的受体失活模型	Rajan, D. H.	PDF	N/A	A receptor-inactivation model for single-celled habituation in Stentor coeruleus
ANKZF1通过LC3介导的线粒体自噬帮助消除应激损伤的线粒体。	Ali, M.	PDF	N/A	ANKZF1 helps to eliminate the stress-damaged mitochondria by LC3-mediated mitophagy
AMP激活蛋白激酶对网格蛋白介导的内吞作用的货物选择性调节	Orofiamma, L. A.	PDF	N/A	Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase
一种用于钙的绿色终身生物传感器，其亮度在其整个动态范围内保持稳定	van der Linden, F. H.	PDF	N/A	A green lifetime biosensor for calcium that remains bright over its full dynamic range
CDR2是一种动力蛋白适配器，被kinectin招募来调节内质网片的组织结构。	Teixeira, V.	PDF	N/A	CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization
使用spoon处理空间分辨转录组数据中的均值-方差关系	Shah, K. H.	PDF	N/A	Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon
光依赖的黄素氧化还原和加合物状态调控转录因子EL222的构象和DNA结合活性	Chaudhari, A. S.	PDF	N/A	Light-dependent flavin redox and adduct states control the conformation and DNA binding activity of the transcription factor EL222
利用带正电荷的可生物降解纳米材料实现体外和体内的mRNA高效递送	Yang, X.	PDF	N/A	Efficient mRNA Delivery In Vitro and In Vivo Using a Polycharged Biodegradable Nanomaterial
通过免疫信息学和计算表位预测设计Mpox疫苗	Rivera-Orellana, S.	PDF	N/A	Mpox Vaccine Design Through Immunoinformatics and Computational Epitope Prediction
VirNA：一种用于研究病毒演化的新型最小生成网络算法	Mazzotti, G.	PDF	N/A	VirNA: a novel Minimum Spanning Networks algorithm for investigating viral evolution
新冠病毒疾病（COVID）后疲劳持续超过12周与基于努力的决策过程中奖励敏感性降低相关。	Scholing, J. M.	PDF	N/A	Fatigue >12 weeks after coronavirus disease (COVID) is associated with reduced reward sensitivity during effort-based decision making
综合宏基因组学和代谢组学揭示了实验性COVID-19中与年龄相关的肠道微生物群和代谢物改变	Rodrigues, P. B.	PDF	N/A	Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in experimental COVID-19
纳米颗粒支持的快速数字化量化针对SARS-CoV-2变种的中和抗体	Mirjalili, S.	PDF	N/A	Nanoparticle-Supported, Rapid, Digital Quantification of Neutralizing Antibodies Against SARS-CoV-2 Variants
BNT162b2 JN.1和KP.2适应型COVID-19疫苗的免疫学和生物物理特性	Chen, W.	PDF	N/A	Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines
利用铜绿假单胞菌荧光绿脓菌素色素开发发光塑料砖	Pandey, K.	PDF	N/A	Development of glowing plastic bricks from waste plastic and florescent pyoverdine pigment of Pseudomonas aeruginosa
抗非生长和胞内细菌的抗菌化合物	Kaldalu, N.	PDF	N/A	Antibacterial Compounds Against Non-Growing and Intracellular Bacteria
一个可访问的3D HepG2/C3A肝球体模型，支持恶性疟原虫在肝细胞内的完整生命周期	Alqurashi, S. O.	PDF	N/A	An Accessible 3D HepG2/C3A Liver Spheroid Model Supporting the Complete Intrahepatocytic Lifecycle of Plasmodium falciparum
微生物学与人类学：在澳大利亚新南威尔士州农村冬季估计死亡时间的多学科方法。	Green, H.	PDF	N/A	Microbiology and Anthropology: a multidisciplinary approach for estimating time since death during Winter in rural New South Wales, Australia.
Lrp1促进Jamestown Canyon病毒对神经元的感染	Frey, Z. D.	PDF	N/A	Lrp1 facilitates infection of neurons by Jamestown Canyon virus
牛瘤胃中大肠杆菌O26:H11、O111:H8和O145:NM血清型的生长动力学及蛋白质表达。	Kudva, I. T.	PDF	N/A	Growth dynamics and protein-expression of Escherichia coli serotypes O26:H11, O111:H8 and O145:NM in the bovine rumen.
增强的胞外基质生成对无细胞壁的大肠杆菌提供了保护作用。	Crooijmans, M. E.	PDF	N/A	Enhanced extracellular matrix production provides protection to cell wall-deficient Escherichia coli
与侵染红松的树皮甲虫相关的长喙壳科真菌，包括在中国发现的新种Ceratocystiopsis fushunensis的描述。	Ran, Y.	PDF	N/A	Ophiostomatalean fungi associated with bark beetles infesting Pinus koraiensis, including the description of Ceratocystiopsis fushunensis sp. nov. in China
病毒样博格古菌染色体外元素与巨型真核病毒的趋同进化	Banfield, J.	PDF	N/A	Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses
通过一种创新的喷枪技术，证明了海洋环境相对于陆地环境缺乏功能性聚酯生物降解潜力。	Contreras-Moll, A.	PDF	N/A	Lack of functional polyester-biodegrading potential in marine versus terrestrial environments evidenced by an innovative airbrushing technique
细菌和真菌中的木质纤维素降解用于生物质转化	Hsin, K.-T.	PDF	N/A	Lignocellulose Degradation in Bacteria and Fungi for Biomass Conversion
通过元蛋白质组学评估水生关键物种在不同饮食下的关键肠道微生物组分和功能	Dumas, T.	PDF	N/A	Key gut microbiota components and functions in an aquatic keystone species across diets assessed by metaproteomics
SCA2/ALS13小鼠模型脊髓磷酸蛋白质组揭示了ATXN2-N端SH3-肌动蛋白相互作用网络的改变，以及通过WNK1-MYO6-OPTN-SQSTM1途径的自噬调控异常	Almaguer-Mederos, L. E.	PDF	N/A	Spinal cord phosphoproteome of a SCA2/ALS13 mouse model reveals alteration of ATXN2-N-term SH3-actin interactome and of autophagy via WNK1-MYO6-OPTN-SQSTM1
MRAP2辅助蛋白直接与黑皮质素-3受体相互作用，以增强信号传导。	Jamaluddin, A.	PDF	N/A	The MRAP2 accessory protein directly interacts with melanocortin-3 receptor to enhance signaling
通过细胞间mRNA转移在体外互补人类疾病表型	Haimovich, G.	PDF	N/A	Complementation of a human disease phenotype in vitro by intercellular mRNA transfer
心脏重编程中的核小体重塑	Harris, S.	PDF	N/A	Nucleosome repositioning in cardiac reprogramming
人类及其他大猿类端粒到端粒基因组中G-四链体的进化动力学	Mohanty, S. K.	PDF	N/A	Evolutionary Dynamics of G-Quadruplexes in Human and Other Great Ape Telomere-to-Telomere Genomes
操纵IKZF1的可变剪接在T细胞中引发不同的基因调控反应	Pastor, L.	PDF	N/A	Manipulation of alternative splicing of IKZF1 elicits distinct gene regulatory responses in T cells
发现嵌合聚酮类家族作为癌症免疫原性化疗先导物	Xue, D.	PDF	N/A	Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads
由跨膜结构域结构可塑性调控的线粒体PINK1的替代进口通道和目的地	Lorriman, J.	PDF	N/A	Alternative Import-Channels And Destinations Of Mitochondrial PINK1 Controlled By Trans-Membrane-Domain Structural Plasticity
在驯养条件下，野生肠道微生物群抑制了斑马鱼体内的机会性病原菌——气单胞菌。	Kawano, K.	PDF	N/A	Wild gut microbiome suppresses the opportunistic pathogen Aeromonas in medaka under domesticated rearing conditions
保守的HIV-1间隔肽2触发基质晶格成熟	Stacey, J. C. V.	PDF	N/A	The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation
长链非编码RNA HSCHARME通过调控在人类心肌病中改变的基因调控网络，促进干细胞衍生心肌细胞的成熟。	Buonaiuto, G.	PDF	N/A	Long noncoding RNA HSCHARME promotes the maturation of stem cells-derived cardiomyocytes by controlling gene regulatory networks altered in human cardiomyopathies
与AMD相关的遗传多态性CFH Y402H使iPSC-RPE细胞对氢醌诱导的压力更为敏感。	Armento, A.	PDF	N/A	The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells
通过在Cas9介导的基因组编辑过程中短暂双重抑制TP53和DNA甲基化，高效重新激活女性hPSC中的XIST。	Motosugi, N.	PDF	N/A	Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing
在PYK2-null小鼠中，内皮细胞中可诱导的FAK缺失而非FAK抑制激活了p53，从而抑制肿瘤生长。	Chen, X. L.	PDF	N/A	Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice
全息显微镜揭示了在血管内皮化过程中，无需标记的内皮细胞定量动力学。	Leineweber, W. D.	PDF	N/A	Holotomographic microscopy reveals label-free quantitative dynamics of endothelial cells during endothelialization
磷脂信号和多泡内溶酶体调节稻瘟菌共生界面处的膜动态变化	Selvaraj, P.	PDF	N/A	Phospholipid signaling and multivesicular endolysosomes modulate membrane dynamics at the biotrophic interface in Rice Blast
RING1 决定 GSDMD 介导的炎症反应及宿主对病原体感染的易感性	Li, Y.	PDF	N/A	RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infection
鸡和鼠神经嵴发育的比较分析	Kulesa, P. M.	PDF	N/A	Comparative Analysis of Neural Crest Development in the Chick and Mouse
Wnt1-Cre2转基因会导致非神经嵴细胞类型的异常重组。	Gandhi, S.	PDF	N/A	The Wnt1-Cre2 transgene causes aberrant recombination in non-neural crest cell types
体外受精引发雄性小鼠后代的生殖变化，并具有多代效应。	Rhon-Calderon, E. A.	PDF	N/A	In Vitro Fertilization induces reproductive changes in male mouse offspring and has multigenerational effects
EEMtoolbox：一个用户友好的R包，用于灵活的集成生态系统建模	Pascal, L. V.	PDF	N/A	EEMtoolbox: A user-friendly R package for flexible ensemble ecosystem modeling
轻踏海底：延绳钓陷阱和钓钩渔具的海底接触定量估算	Doherty, B.	PDF	N/A	Treading lightly: Quantitative estimates of seafloor contact for longline trap and hook fishing gear
自上而下的气候过程调节北美森林中的生物多样性与功能关系	Maluquer, X. S.	PDF	N/A	TOP-DOWN CLIMATIC PROCESSES MODULATE BIODIVERSITY-FUNCTIONING RELATIONSHIPS ACROSS NORTH AMERICAN FORESTS
鱼类研究的边界？伊塔蒂亚亚探险与生物多样性数据库揭示了巴西高海拔水生生态系统中鱼类分布的空白	Soares Guedes, G. H.	PDF	N/A	A fish frontier? Itatiaia expedition and biodiversity repositories reveal gaps in fish occurrences in Brazil's high-altitude aquatic ecosystems
湿度和竞争限制了埋葬甲繁殖的短暂资源质量	Hayes, T. E.	PDF	N/A	Moisture and competition constrain ephemeral resource quality for burying beetle reproduction
电鳐科（Narcinidae，Gill, 1862）电鳐的谱系地理学：系统回顾与美洲扩散路径的证据。	Rodrigues-Filho, L. F. S.	PDF	N/A	Phylogeography of the electric rays of the family Narcinidae (Gill, 1862): systematic review and evidence of the dispersal routes to America.
啤酒花中X-A平衡性决定系统的进化与功能	Akagi, T.	PDF	N/A	Evolution and functioning of an X-A balance sex determination system in hops
由自由基和类过氧桥相互作用驱动的TCA循环中的C-C键断裂与生成	Yang, L.	PDF	N/A	C-C bond cleavage and generation in TCA cycle driven by radicals and peroxo-bridge like interaction
开发新型可切割交联剂试剂用于细胞内交联的探索之旅	Mueller, F.	PDF	N/A	A journey towards developing a new cleavable crosslinker reagent for in-cell crosslinking
AistSeq：一种基于Tn5的内部质粒测序平台，采用紧凑型台式测序仪	Suzuki, H.	PDF	N/A	AistSeq: An In-House Tn5-Based Plasmid Sequencing Platform Using A Compact Benchtop Sequencer
利用3D nnUnet和光片显微镜进行自动细胞追踪，以量化斑马鱼中的区域变形	Teranikar, T. A.	PDF	N/A	Automated cell tracking using 3D nnUnet and Light Sheet Microscopy to quantify regional deformation in zebrafish
血小板膜包覆的超顺磁性氧化铁纳米粒子用于癌症治疗中的靶向紫杉醇递送和磁热疗	Tavakoli, M.	PDF	N/A	Platelet Membrane-Coated SPION for Targeted Paclitaxel Delivery and Magnetic Hyperthermia in Cancer Therapy
金属离子对DNA纳米结构等温自组装的影响	Rodriguez, A.	PDF	N/A	Influence of metal ions on the isothermal self-assembly of DNA nanostructures
SingleFrag：一种用于MS/MS片段和光谱预测及代谢物注释的深度学习工具	Perez-Ribera, M.	PDF	N/A	SingleFrag: A deep learning tool for MS/MS fragment and spectral prediction and metabolite annotation
多阶张量的统一分析用于综合分子特征分析	De Azevedo, K.	PDF	N/A	Unified Analysis of Multi-order Tensors for Integrative Molecular Profiling
通过剪接进化的视角增强转录组注释	Zang, X. C.	PDF	N/A	Augmenting Transcriptome Annotations through the Lens of Splicing Evolution
Rthoptera：R语言中的标准化昆虫生物声学分析工具	Rivas, F.	PDF	N/A	Rthoptera: standardized insect bioacoustics in R
胡萝卜中的植物化学物质对三阴性乳腺癌PDK1和PLK1具有治疗潜力。	Raheem, k.	PDF	N/A	Phytochemicals from Daucus carota have therapeutic potential against Triple-Negative Breast Cancer PDK1 and PLK1.
TomoPicker：冷冻电子断层扫描中的注释高效粒子挑选	Uddin, M. R.	PDF	N/A	TomoPicker: Annotation-Efficient Particle Picking in cryo-electron Tomograms
G4-Attention：用于预测DNA G-四链体的带注意力机制的深度学习模型	Mukherjee, S.	PDF	N/A	G4-Attention: Deep Learning Model with Attention for predicting DNA G-Quadruplexes
阶段特异性基因比率突显了与无症状和有症状多发性骨髓瘤相关的基因和机制。	Georgiou, G.	PDF	N/A	Stage-specific gene ratios highlight genes and mechanisms related to presymptomatic and symptomatic Multiple Myeloma
单细胞分辨率下的转录组装配与海狸	Shi, Q.	PDF	N/A	Transcriptome Assembly at Single-Cell Resolution with Beaver
PAIRWISE：基于深度学习的癌症个性化药物组合有效性预测	Xu, C.	PDF	N/A	PAIRWISE: Deep Learning-based Prediction of Effective Personalized Drug Combinations in Cancer
Biosynth Pipeline：一个集成平台，用于将嵌合型I类聚酮合酶的计算设计与化学生物合成的酶促途径相结合	Chainani, Y.	PDF	N/A	Biosynth Pipeline: An integrated platform for merging the computational design of chimeric type I polyketide synthases with enzymatic pathways for chemical biosynthesis
单细胞转录组学揭示非酒精性脂肪肝疾病的基因组指标	Thakur, M.	PDF	N/A	Single Cell Transcriptomics Reveal Genomic Indicators of Nonalcoholic Fatty Liver Disease
用于冷冻电镜图像处理的全面基础模型	Yan, Y.	PDF	N/A	A comprehensive foundation model for cryo-EM image processing
mcBERT：患者级单细胞转录组数据表示	Querfurth, B. v.	PDF	N/A	mcBERT: Patient-Level Single-cell Transcriptomics Data Representation
单细胞数据自监督学习的基准测试	Toma, P.	PDF	N/A	Benchmarking Self-Supervised Learning for Single-Cell Data
使用随机丙氨酸序列扫描结合AlphaFold2中的浅层子采样评估无配体和有配体蛋白质状态的结构与构象集合：对功能别构构象预测的见解与教训	Raisinghani, N.	PDF	N/A	Assessing Structures and Conformational Ensembles of Apo and Holo Protein States Using Randomized Alanine Sequence Scanning Combined with Shallow Subsampling in AlphaFold2 : Insights and Lessons from Predictions of Functional Allosteric Conformations
微管动态由聚类原丝的构象和稳定性所决定。	Kalutskii, M.	PDF	N/A	Microtubule dynamics are defined by conformations and stability of clustered protofilaments
酸性条件促进癌细胞来源的细胞外囊泡聚集，并增强其与合成脂质体的融合	Fisher, W. S.	PDF	N/A	Acidic Conditions Promote Clustering of Cancer Cell Derived Extracellular Vesicles and Enhance their Fusion with Synthetic Liposomes
DNA序列对ZTA转录因子-DNA复合物的热力学和结构稳定性的影响：一项全原子分子动力学研究	Duraisamy, B.	PDF	N/A	Influence of DNA sequences on thermodynamic and structural stability of ZTA transcription factor - DNA complex: An all-atom molecular dynamics study
肌动蛋白周转和肌球蛋白收缩力决定了模拟细胞皮层的突现厚度鲁棒性	Gat, S.	PDF	N/A	Actin turnover and myosin contractility determine emergent Thickness Robustness of Cell-Mimicking Cortex
蛋白质动力学构成了热感受器对温度强烈依赖的基础	Qin, F.	PDF	N/A	Protein Dynamics Underlies Strong Temperature Dependence of Heat Receptors
Tau-微管蛋白共凝聚物在早期微管组织中的结构化作用	Lee-Eom, C.	PDF	N/A	Structuring Role of Tau-Tubulin Co-Condensates in Early Microtubule Organization
神经肽Y在水溶液中的pH依赖性结构动态变化	Nguyen, T. H.	PDF	N/A	pH-dependent structural dynamics of the neuropeptide Y in aqueous solution
等离子体膜囊泡和磷脂酰胆碱-胆固醇囊泡的形状揭示了它们的有效自发曲率	Kaur, H.	PDF	N/A	Shapes of Plasma Membrane Vesicles and PC-Cholesterol Vesicles Reveal Their Effective Spontaneous Curvature
RNA梯度可以引导凝聚物向启动子区域移动：这对增强子-启动子接触以及凝聚物-启动子亲吻现象具有重要意义。	Goh, D.	PDF	N/A	RNA gradients can guide condensates toward promoters: implications for enhancer-promoter contacts and condensate-promoter kissing
支气管镜诱导的转基因肺癌猪模型的人类可转化性特征	Joshi, K.	PDF	N/A	Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability
阻断SHP2可增强FGFR2抑制剂的作用，并克服FGFR2扩增型胃癌中的耐药性。	Zhang, Y.	PDF	N/A	Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer
癌症中N基因和T基因的动力学	Perez, G. J. G.	PDF	N/A	Dynamics of N-genes and T-genes in cancer
通过SdFFF和UHF-DEP标准化方法对结直肠癌细胞的特征化和分离：转录组分析强调	JEMFER, C.	PDF	N/A	Towards a standardised method for the characterisation and isolation of colorectal cancer stem cells by SdFFF and UHF-DEP: highlighted by transcriptomic analysis
腱生蛋白-C增强甲状腺癌中的Wnt信号传导	Hartmann, H. A.	PDF	N/A	Tenascin-C potentiates Wnt signaling in thyroid cancer
氯吡硫磷诱导肺转移并调节三阴性乳腺癌模型中的癌症干细胞标志物	Lasagna, M.	PDF	N/A	Chlorpyrifos induces lung metastases and modulation of cancer stem cell markers in triple negative breast cancer model
MPS1抑制剂NTRC 0066-0在体外和体内对胶质母细胞瘤疗效之间的脱节	de Gooijer, M. C.	PDF	N/A	Disconnect between in vitro and in vivo efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma
血小板特异性P2Y1受体缺陷小鼠对脂多糖的反应中白细胞募集受到抑制。	Pan, D.	PDF	N/A	Platelet-specific P2Y1 receptor deficient mice have suppressed leukocyte recruitment in response to lipopolysaccharide.
Septins通过调节心肌细胞的储存操作钙内流来调控心脏收缩力。	Tripoli, B. A.	PDF	N/A	Septins regulate heart contractility through modulation of cardiomyocyte store-operated calcium entry
循环小鼠来源的外泌体调节围绝经期小鼠肝脏转录组，与年龄无关	Zanini, B.	PDF	N/A	EXOSOMES FROM CYCLIC MICE MODULATE LIVER TRANSCRIPTOME IN ESTROUPAUSE MICE INDEPENDENT OF AGE
利用基于集成网络的系统生物学方法预测与水稻（Oryza sativa）种子发育相关的新候选蛋白质，并分析其子模块和蛋白质枢纽。	De Silva, M. R. P.	PDF	N/A	Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice (Oryza sativa) using an ensemble network-based systems biology approach.
发现和利用主动感知模式以实现基于经验可观测性的估计	Cellini, B.	PDF	N/A	Discovering and exploiting active sensing motifs forestimation with empirical observability
高效有限差分法估计随机离散生化系统的二阶参数敏感性	Jabeen, F.	PDF	N/A	Efficient Finite-Difference Estimation of Second-Order Parametric Sensitivities for Stochastic Discrete Biochemical Systems
一项针对心力衰竭的跨研究转录患者图谱揭示了心脏重塑过程中保守的多细胞协调机制。	Lanzer, J. D.	PDF	N/A	A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling
常见的长足海绵属海绵花园：东北太平洋长足海绵科的分类修订揭示了许多隐秘的引入物种	Turner, T. L.	PDF	N/A	A common garden of Halichondria sponges: taxonomic revision of Northeast Pacific Halichondriidae reveals many cryptic introduced species
血红素氧合酶-1对干扰素刺激基因表达的影响	Chudy, P.	PDF	N/A	Effect of heme oxygenase-1 on the expression of interferon-stimulated genes
使用PANDORA进行MHC II类分子的双向肽构象预测	Rademaker, D. T.	PDF	N/A	Bidirectional Peptide Conformation Prediction for MHC Class II using PANDORA
TRPV4介导的机械转导调控瓣膜间质细胞向肌成纤维细胞的分化：对主动脉瓣狭窄的启示	Mukherjee, P.	PDF	N/A	TRPV4-mediated Mechanotransduction Regulates the Differentiation of Valvular Interstitial Cells to Myofibroblasts: Implications for Aortic Stenosis
Aramchol 减轻了胆道纤维化小鼠模型中的纤维化，并阻断了 TGFβ 诱导的胆管细胞中的纤维炎症介质。	Aseem, S. O.	PDF	N/A	Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes
Miro1表达改变全局基因表达、ERK1/2磷酸化、氧化应激以及细胞周期进程	Shannon, N.	PDF	N/A	Miro1 expression alters global gene expression, ERK1/2 phosphorylation, oxidation, and cell cycle progression
HumanTestisDB：睾丸转录组学和细胞相互作用的综合图谱	Wang, M.	PDF	N/A	HumanTestisDB: A Comprehensive Atlas of Testicular Transcriptomics and Cellular Interactions
衰老对小鼠骨折后免疫和骨膜反应的影响	King, J. S.	PDF	N/A	Effects of Aging on the Immune and Periosteal Response to Fracture in Mice
抑制DPP4活性通过支持脂肪酸和嘌呤代谢以及减轻炎症来保护由hiPSC衍生的脂肪性肝细胞（HLCs）。	Loerch, C.	PDF	N/A	Inhibiting DPP4 activity protects hiPSC-derived steatotic HLCs by supporting fatty acid and purine metabolism and dampening inflammation
L-乳酸通过MCT1运输、诱导代谢重编程和基因表达调控，诱导短期和长期的心脏保护作用。	Cler, M.	PDF	N/A	L-lactic acid induces short- and long-term cardioprotective effects through MCT1 transport, induction of metabolic reprogramming, and gene expression modulation.
CXXC5是一种泛素化蛋白，通过泛素化-蛋白酶体途径被降解。	Ayten, H.	PDF	N/A	CXXC5 is a ubiquitinated protein and is degraded by the ubiquitination-proteasome pathway
新型小麦胚凝集素基质谱流式细胞术细胞条码标记试剂，适用于异质性、活体或固定样本	Hannan, R. T.	PDF	N/A	Novel wheat germ agglutinin-based mass cytometry cell barcoding reagent for heterogeneous, live or fixed sample
口服暴露于PET微塑料会改变胰腺转录组——这对1型糖尿病的发病机制具有重要意义	Mierzejewski, K.	PDF	N/A	Oral exposure to PET microplastics alters the pancreatic transcriptome-implications for the pathogenesis of type 1 diabetes
不对称基因流动维持着丰富的分布中心	Hancock, Z. B.	PDF	N/A	Asymmetric gene flow maintains an abundant range center
子宫接受性的标志早于胎盘哺乳动物出现	Basanta, S.	PDF	N/A	Hallmarks of uterine receptivity predate placental mammals
玉米重组景观在驯化过程中发生了演变。	Epstein, R.	PDF	N/A	The maize recombination landscape evolved during domestication.
通过比较转录组学深入了解四足动物双锥体的进化起源	Tommasini, D.	PDF	N/A	Comparative transcriptomic insights into the evolutionary origin of the tetrapod double cone
阿尔法细胞理论：模拟生命系统中的自组装和动态过程	Gruhlke, M. C. H.	PDF	N/A	Alpha Cell Theory: Modeling Self-Assembly and Dynamic Processes in Living Systems
氨基酸性质、替代速率以及近中性理论	James, J.	PDF	N/A	Amino acid properties, substitution rates, and the nearly neutral theory
范围扩张的历史生物地理学预测了繁殖保障的空间模式	Urquhart-Cronish, M.	PDF	N/A	The historical biogeography of range expansion predicts spatial patterns in reproductive assurance
磁性细菌在天然孔隙网络中实现最佳导航	Petroff, A. P.	PDF	N/A	Magnetotactic Bacteria Optimally Navigate Natural Pore Networks
细菌生命树中利福平抗性的进化与可进化性	Bolourchi, N.	PDF	N/A	Evolution and evolvability of rifampicin resistance across the bacterial tree of life
在免疫检查点阻断的背景下定义CD8+ T细胞受体库的遗传决定因素	Ng, E.	PDF	N/A	Defining the genetic determinants of CD8+ T cell receptor repertoire in the context of immune checkpoint blockade
以单个氨基酸分辨率进行蛋白质测序可以识别出区分肌动蛋白原形态的肽段。	Sittipongpittaya, N.	PDF	N/A	Protein sequencing with single amino acid resolution discerns peptides that discriminate tropomyosin proteoforms
长寿中的玛土撒拉蛋白：通过数学基因组学揭示其影响	Hassan, S. S.	PDF	N/A	Methuselah Proteins in Longevity: Unraveling Their Impact Through Mathematical Genomics
去氨酶辅助的单分子和单细胞染色质纤维测序	Swanson, E. G.	PDF	N/A	Deaminase-assisted single-molecule and single-cell chromatin fiber sequencing
新生转录本O-MAP揭示了由RBM20和TTN RNA构建的单基因位点亚核区室的分子结构	Kania, E. E.	PDF	N/A	Nascent transcript O-MAP reveals the molecular architecture of a single-locus subnuclear compartment built by RBM20 and the TTN RNA
# BioRxiv 2024-11-05 Papers

标题	作者	PDF链接	代码仓库	Title
YAP通过Rho-GTPase开关控制细胞迁移和侵袭	Shah, S. R.	PDF	N/A	YAP controls cell migration and invasion through a Rho-GTPase switch
益生菌治疗鼻腔金黄色葡萄球菌去定植的计算和体外评估	Tepekule, B.	PDF	N/A	Computational and in vitro evaluation of probiotic treatments for nasal Staphylococcus aureus decolonization
转录组数据揭示了食蚁兽和穿山甲在饮食趋同背景下几丁质酶进化的不同路径	Allio, R.	PDF	N/A	Transcriptomic data reveal divergent paths of chitinase evolution underlying dietary convergence in anteaters and pangolins
用于多重行为学和单细胞转录组学研究的确定性遗传条形码技术	Mendana, J. B.	PDF	N/A	Deterministic Genetic Barcoding for Multiplexed Behavioral and Single-Cell Transcriptomic Studies
最长命哺乳动物中的DNA修复与抗癌机制：弓头鲸	Firsanov, D.	PDF	N/A	DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale
活性粒子诱导的网络范围张力波动对脂质泡沫原组织进行重塑	Gu, A. A.	PDF	N/A	Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles
解码视觉空间注意力控制	Meyyappan, S.	PDF	N/A	Decoding Visual Spatial Attention Control
Tgfbr1 调控侧板中胚层和内胚层在躯干向尾部过渡期间的重组	Lozovska, A.	PDF	N/A	Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition
厘米级组织和胚胎中大量异质细胞群体的体积跨尺度成像	Ichimura, T.	PDF	N/A	Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo
免疫缺陷相关激活型PIK3R1变异的矛盾性显性负性活性	Tomlinson, P. R.	PDF	N/A	Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
脱轨细胞状态的联合表示与可视化：Decipher	Nazaret, A.	PDF	N/A	Joint representation and visualization of derailed cell states with Decipher
脑网络动态在不同情境下预测惊讶时刻	Zhang, Z.	PDF	N/A	Brain network dynamics predict moments of surprise across contexts
BRD4介导的内质网-线粒体接触位点的表观遗传调控受线粒体复合物III的调控。	Chen, B.	PDF	N/A	BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III
在狨猴对中，性别和熟悉程度对社交凝视的动态调节	Xing, F.	PDF	N/A	Dynamic modulation of social gaze by sex and familiarity in marmoset dyads
CTCF锚定的染色质环在人类减数分裂期间的动力学	Kaiser, V. B.	PDF	N/A	CTCF-anchored chromatin loop dynamics during human meiosis
从头检测高质量长读长单细胞RNA测序数据中的体细胞变异	Dondi, A.	PDF	N/A	De novo detection of somatic variants in high-quality long-read single-cell RNA sequencing data
水熊虫Hypsibius exemplaris中通过qRT-PCR比较相对转录水平的单动物、单管RNA提取方法。	Kirk, M. J.	PDF	N/A	Single-animal, single-tube RNA extraction for comparison of relative transcript levels via qRT-PCR in the tardigrade Hypsibius exemplaris.
PIPETS：一种基于统计学原理、不依赖基因注释的分析方法，用于通过3'-端测序研究细菌终止机制。	Furumo, Q.	PDF	N/A	PIPETS: A statistically informed, gene-annotation agnostic analysis method to study bacterial termination using 3'-end sequencing.
moPepGen：快速全面鉴定非规范肽	Zhu, C.	PDF	N/A	moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides
新胱氨酸摇篮家族中的一个典型成员是一种aECM蛋白，它在秀丽隐杆线虫中传递皮肤损伤的信号。	Sonntag, T.	PDF	N/A	A defining member of the new cysteine-cradle family is an aECM protein signalling skin damage in C. elegans
优化系统发育特征向量回归中的变量选择以进行性状相关性分析	Chen, Z.-L.	PDF	N/A	Optimizing Variable Selection in Phylogenetic Eigenvector Regression for Trait Correlation Analysis
斑马鱼作为研究PERK功能在发育性疾病中的作用的模式生物：对Wolcott-Rallison综合征的启示	Almeida, L. M.	PDF	N/A	Zebrafish as a model to study PERK function in developmental diseases: implications for Wolcott-Rallison syndrome
解决SARS-CoV-2系统发育中的大流行性系统错误	Hunt, M.	PDF	N/A	Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny
新型酵母共生体的设计及其在酿酒发酵生态研究中的应用	Pourcelot, E.	PDF	N/A	Design of a new model yeast consortium for ecological studies of enological fermentation
Ezrin通过EGFR-AKT信号通路在细胞内小泡区室中定义了TSC复合物的激活。	Giamundo, G.	PDF	N/A	Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling.
表皮胶原蛋白主动调节感觉神经元的衰老	Krishna, M.	PDF	N/A	Epidermal Collagen Actively Regulates the Aging of Sensory Neurons
线性感知运动转换解释了人类航向估计中与反应范围相关的偏差	Sun, Q.	PDF	N/A	A linear sensorimotor transformation accounts for response range-dependent biases in human heading estimation
消化和肠腔流动的昼夜变化决定了人类大肠微生物群落的动态变化。	Salari, A.	PDF	N/A	Diurnal variations in digestion and luminal flow determine microbial population dynamics along the human large intestine
发条猩猩：微小RNA、体温调节权衡与脑容量进化。	Fromm, B.	PDF	N/A	Clockwork Orangutan: microRNAs, thermoregulatory tradeoffs, and the evolution of brain size.
RNA会根据需要调整其灵活性，以便高效折叠并抵抗展开。	Jang, S. S.	PDF	N/A	RNA adapts its flexibility to efficiently fold and resist unfolding
基于人工智能的新型药物-基因-疾病相互作用识别方法，利用蛋白质-蛋白质相互作用	Taguchi, Y.-h.	PDF	N/A	Novel artificial intelligence-based identification of drug-gene-disease interaction using protein-protein interaction
片段化DNA的“深度采样”PCR揭示了克氏锥虫在慢性感染宿主中的广泛负担范围，并允许在治疗后对寄生虫负荷进行准确监测。	White, B. E.	PDF	N/A	Serial "deep-sampling" PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected hosts and allows accurate monitoring of parasite load following treatment
与淀粉样变性、溶酶体不稳定和出血相关的病理性轴突增大是阿尔茨海默病中的主要缺陷。	Fu, H.	PDF	N/A	Pathological axonal enlargement in connection with amyloidosis, lysosome destabilization and hemorrhage is a major defect in Alzheimer's disease
在热带森林实验中，树木多样性增加了地上的碳储存和通量，但对地下的碳储存和通量没有影响。	Schnabel, F.	PDF	N/A	Tree diversity increases carbon stocks and fluxes above- but not belowground in a tropical forest experiment
通过细胞类型动态系统解析不同细胞类群的作用	Jha, A.	PDF	N/A	Disentangling the Roles of Distinct Cell Classes with Cell-Type Dynamical Systems
人类微生物组的综合生物合成分析揭示了多样化的保护性核糖体肽	ZHANG, J.	PDF	N/A	Comprehensive Biosynthetic Analysis of Human Microbiome Reveals Diverse Protective Ribosomal Peptides
在猕猴视觉注意过程中小脑齿状核神经元活动的编码	Flierman, N. A.	PDF	N/A	Encoding of cerebellar dentate neuronal activity during visual attention in rhesus macaques
个体间声道的多样性影响口语语言的语音多样化	Moran, S.	PDF	N/A	Interindividual vocal tract diversity influences the phonetic diversification of spoken languages
机器学习揭示关键糖蛋白突变并快速划分拉沙病毒谱系	Daodu, R. O.	PDF	N/A	Machine Learning Reveals Key Glycoprotein Mutations and Rapidly Assigns Lassa Virus Lineages
极性建立和中心体纺锤体独立性细胞分裂的最小数学模型	Maxian, O.	PDF	N/A	A minimal mathematical model for polarity establishment and centralspindlin-independent cytokinesis
通过单胺能核团内固有调制对功能上不同的输入进行多路复用，以调节放电时序	Lynn, M. B.	PDF	N/A	Multiplexing of functionally distinct inputs by intrinsic modulation of spike timing in a monoaminergic nucleus
消除常见的神经选择信号并不会使它们成为人工产物。对Frömer等人（2024年，《自然·人类行为》）的评论。	O'Connell, R. G.	PDF	N/A	Regressing Away Common Neural Choice Signals does not make them Artifacts. Comment on Frömer et al (2024, Nature Human Behaviour)
气候变化与病原体多样性之间的相互作用塑造了农业环境中地方性疾病的动力学	Bhandari, R.	PDF	N/A	Interaction between climatic variation and pathogen diversity shape endemic disease dynamics in the agricultural settings
空间转录组学的基因表达框架	Cao, S.	PDF	N/A	A gene representation framework for spatial transcriptomics
体内T细胞共调节因子B7-H4的成像揭示了前列腺癌中的促肿瘤巨噬细胞状态	Kumar, M.	PDF	N/A	In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer
一种综合的蛋白质组学和转录组学方法揭示了新的ADAM9底物及其下游通路	Lu, C.	PDF	N/A	An integrative proteotranscriptomics approach reveals new ADAM9 substrates and downstream pathways
模块化噬菌体T4纳米颗粒平台助力快速设计双效COVID-19-流感黏膜疫苗	Zhu, J.	PDF	N/A	A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID-19-Flu Mucosal Vaccines
代谢微调与心脏细胞因子分泌是果蝇对高脂肪和高糖饮食的适应性反应。	Khamvongsa-Charbonnier, L.	PDF	N/A	Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies
食物摄入增强了海马体的锋电位波纹复合体。	Kaya, E.	PDF	N/A	Food intake enhances hippocampal sharp wave-ripples
EphA2 和磷酸抗原介导的 γδT 细胞对髓母细胞瘤的选择性杀伤保护了神经元和干细胞的完整性	Boutin, L.	PDF	N/A	EphA2 and Phosphoantigen-Mediated Selective Killing of Medulloblastoma by γδT Cells Preserves Neuronal and Stem Cell Integrity
β-肾上腺素能阻滞剂通过胰腺β细胞中的PKA/RYR2/TRPM5途径增加cAMP并刺激胰岛素分泌，此过程在体外实验中得到验证。	Murao, N.	PDF	N/A	β-adrenergic blockers increase cAMP and stimulate insulin secretion through a PKA/RYR2/TRPM5 pathway in pancreatic β-cells in vitro
发现广谱细菌多胺解毒抑制剂作为潜在的抗毒力剂和抗生素佐剂	Moulding, P. B.	PDF	N/A	Discovery of broad-spectrum bacterial polyamine detoxification inhibitors as potential antivirulence agents and antibiotic adjuvants
人类在空间导航过程中前额叶Theta波和顶叶Alpha波振荡事件的单次试验特征	Cuello, M. T.	PDF	N/A	Single trial characterization of frontal Theta and parietal Alpha oscillatory episodes during Spatial Navigation in humans
经典的统计方法在识别乳腺癌患者生存的新靶点方面具有强大的作用。	Insawang, B.	PDF	N/A	Classical statistical methods are powerful for the identification of novel targets for the survival of breast cancer patients
利用智能手机RGB图像和LiDAR点云进行增强的叶片氮素和地上生物量评估——以中国菠菜为案例研究	Harikumar, A.	PDF	N/A	Harnessing Smartphone RGB Imagery and LiDAR Point Cloud for Enhanced Leaf Nitrogen and Shoot Biomass Assessment - Chinese Spinach as a Case Study
比较时空单细胞转录组揭示了C4草类Kranz解剖结构出现过程中预存调控的重塑	Zhao, C.	PDF	N/A	Comparative spatiotemporal single cell transcriptomes reveal rewiring of pre-existing regulations during emergence of Kranz anatomy in C4 grasses
一种组合域筛选平台揭示了表观遗传效应因子与转录扰动之间的相互作用	Moon, H. C.	PDF	N/A	A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation
有机和无机污染物及其混合物对发育期暴露斑马鱼代谢健康和基因表达的影响	Berube, R.	PDF	N/A	Effects of organic and inorganic contaminants and their mixtures on metabolic health and gene expression in developmentally exposed zebrafish
利用多环境试验育种数据优化基因型特异性参数评估木薯作物生长模型	Okoma, P. M.	PDF	N/A	Evaluating a Cassava Crop Growth Model by Optimizing Genotypic-Specific Parameters Using Multi-environment Trial Breeding Data
C3-C3aR轴调控肺泡巨噬细胞的训练免疫	Earhart, A. P.	PDF	N/A	The C3-C3aR axis modulates trained immunity in alveolar macrophages
Squeakuences：一种便携式工具，用于格式化无瑕疵的序列，以消除生物信息学软件的不兼容性	Lane, L. E.	PDF	N/A	Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities
探索恶性疟原虫二氢叶酸还原酶的适应性景观：抗叶酸耐药性的进化见解	Muzata, D.	PDF	N/A	Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance
一种全球性的多巴胺能学习率能够使适应性觅食在众多选择中进行。	Grima, L. L.	PDF	N/A	A global dopaminergic learning rate enables adaptive foraging across many options
验证DXS作为分枝杆菌中具有吸引力的药物靶点	Maila, T.	PDF	N/A	Validation of DXS as an attractive drug target in mycobacteria
神经溶酶体定位与功能的小分子调节剂可解决培养的人类神经元中与阿尔茨海默病相关的病理	Snead, A. M.	PDF	N/A	Small molecule modulator of neuronal lysosome positioning and function resolves Alzheimers Disease-linked pathologies in cultured human neurons
小鼠新皮层深层6层兴奋性神经元的共识定义	Kim, S.-J.	PDF	N/A	A consensus definition for deep layer 6 excitatory neurons in mouse neocortex
皮质纹状体投射招募黑质外侧部多巴胺能神经元用于听觉威胁记忆	Sansalone, L.	PDF	N/A	Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories
保守开花基因的顺式调控元件的拮抗作用介导了发育的稳健性。	Lanctot, A.	PDF	N/A	Antagonizing cis-regulatory elements of a conserved flowering gene mediate developmental robustness
对蝾螈Y染色体转换的鉴定未能支持Triturus平衡致死系统起源于性染色体的观点	France, J. M.	PDF	N/A	Identification of Y-chromosome turnover in newts fails to support a sex chromosome origin for the Triturus balanced lethal system
xIV-LDDMM工具包：一套基于图像-变分技术的工具，用于在多尺度上同时表示和映射三维成像和空间组学数据	Stouffer, K.	PDF	N/A	xIV-LDDMM Toolkit: A Suite of Image-Varifold Based Technologies for Representing and Mapping 3D Imaging and Spatial-omics Data Simultaneously Across Scales
一种高山植物在冰川后迅速扩张的范围内没有表现出遗传多样性的下降。	Urquhart-Cronish, M.	PDF	N/A	An alpine plant shows no decrease in genetic diversity associated with rapid post-glacial range expansion
丛枝菌根真菌中转座元件的分析支持其与植物病原真菌在进化上的相似性	Oliveira, J. I.	PDF	N/A	Analyses of transposable elements in arbuscular mycorrhizal fungi support evolutionary parallels with fungal plant pathogens
对丛枝菌根真菌中转座子元素的分析支持其与丝状植物病原体在进化上的平行性。	Oliveira, J. I.	PDF	N/A	Analyses of transposable elements in arbuscular mycorrhizal fungi support evolutionary parallels with filamentous plant pathogens
SeedMatExplorer：拟南芥种子成熟转录组图谱	Artur, M. A. S.	PDF	N/A	SeedMatExplorer: The transcriptome atlas of Arabidopsis seed maturation
PII蛋白与BADC和BCCP蛋白的相互作用共同调控拟南芥中的脂质和氮代谢	Garneau, M. G.	PDF	N/A	PII interactions with BADC and BCCP proteins co-regulate lipid and nitrogen metabolism in Arabidopsis
5-甲基胞嘧啶DNA糖基化酶ROS1对抗拟南芥胚乳中亲本特异性DNA甲基化	Hemenway, E. A.	PDF	N/A	The 5-methylcytosine DNA glycosylase ROS1 antagonizes parent-of-origin specific DNA methylation in Arabidopsis endosperm
高温和微生物群落条件影响大豆基因表达	Van der Laan, L.	PDF	N/A	High Temperature and Microbiome Conditions Affect Gene Expression in Soybean
红藻Galdieria sulphuraria NIES-3638中PSI-LHCI复合物的LHCI蛋白多样性的生化证据	Nagao, R.	PDF	N/A	Biochemical evidence for the diversity of LHCI proteins in PSI-LHCI from the red alga Galdieria sulphuraria NIES-3638
衰老促使植物器官中DNA甲基化衰减的程序启动	Dai, D.	PDF	N/A	Aging drives a program of DNA methylation decay in plant organs
PATROL1介导的H+-ATP酶转运通过优化根和叶的功能，在干旱条件下促进植物生长。	Katsuhama, N.	PDF	N/A	PATROL1-mediated H+-ATPase translocation boosts plant growth under drought by optimizing root and leaf functions
番茄根系对细菌来源的肽表现出明显的、与发育阶段相关的反应	Leuschen-Kohl, R. L.	PDF	N/A	Tomato roots exhibit distinct, development-specific responses to bacterial-derived peptides
压缩力通过ERK信号通路诱导衰老的人类真皮成纤维细胞的表观遗传激活	Liu, H.	PDF	N/A	Compressive forces induce epigenetic activation of aged human dermal fibroblasts through ERK signalling pathway
KLF7调控的ITGA2作为抑制口腔癌干细胞的治疗靶点	QI, X.	PDF	N/A	KLF7-Regulated ITGA2 as a Therapeutic Target for Inhibiting Oral Cancer Stem Cells
靶向黑色素瘤细胞的能量代谢：FX-11作为线粒体解偶联剂	Preis, J. R.	PDF	N/A	Targeting the energy metabolism of melanoma cells: FX-11 acts as a mitochondrial uncoupler
一种罕见的造血干细胞来源的巨核细胞祖细胞通过增强的存活而积累，并在衰老时促进血栓形成加剧	Manso, B. A.	PDF	N/A	A rare HSC-derived megakaryocyte progenitor accumulates via enhanced survival and contributes to exacerbated thrombopoiesis upon aging
草酸铁钾纳米颗粒在小鼠模型中可预防人类血液凝固和血栓形成	Yenurkar, D.	PDF	N/A	Potassium ferric oxalate nanoparticles prevent human blood clotting and thrombosis in a mouse model
基于EEG连接组的健康受试者非言语智力水平的预测建模	Pashkov, A. A.	PDF	N/A	EEG connectome-based predictive modeling of nonverbal intelligence level in healthy subjects
通过Sac1依赖的PI(4)P和胆固醇的共同调控来控制高尔基体V-ATPase	Zhou, X.	PDF	N/A	Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol
TFG环复合体在神经元货物运输中具有多种作用	Zhang, Z.	PDF	N/A	Multiple roles for TFG ring complexes in neuronal cargo trafficking
微管锚定因子NEDD1与γ-微管蛋白环复合物结合的结构	Munoz Hernandez, H.	PDF	N/A	Structure of the microtubule anchoring factor NEDD1 bound to the γ-tubulin ring complex
用于冷冻电镜断层成像颗粒挑选机器学习竞赛的开源工具	Harrington, K. I.	PDF	N/A	Open-source Tools for CryoET Particle Picking Machine Learning Competitions
中和抗体对SARS-CoV-2 JN.1变种KP.3、KP.3.1.1、LB.1和XEC的逃逸	Sano, K.	PDF	N/A	Neutralizing antibody evasion of SARS-CoV-2 JN.1 derivatives KP.3, KP.3.1.1, LB.1, and XEC
两种致病真菌中将单倍体染色体分配到不同细胞核的过程	Li, X.	PDF	N/A	Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi
通过额外结合髓鞘少突胶质细胞糖蛋白（一种中枢神经系统特异性蛋白），延长抗体在大脑中的半衰期	Cuypers, M.-L.	PDF	N/A	Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein
用于DNA数据存储中无PCR随机访问的纳米孔测序自适应采样	Sokolovskii, R.	PDF	N/A	Adaptive sampling in nanopore sequencing for PCR-free random access in DNA data storage
DNA-SaM是一种用于大规模数据存储的强大系统。	Huang, X.	PDF	N/A	DNA-SaM, a robust system for large-scale data storage
A群链球菌碳水化合物生物合成基因的自然变异影响宿主-病原体相互作用	Tamminga, S. M.	PDF	N/A	Natural variation of the streptococcal Group A carbohydrate biosynthesis genes impacts host-pathogen interaction
粘附侵袭性大肠杆菌对环丙沙星的持久性表型，揭示了高持久性菌株	Perez-Villalobos, V.	PDF	N/A	Persistence phenotype of adherent-invasive Escherichia coli in response to ciprofloxacin, revealing high-persistence strains
临床环境中大肠埃希菌菌株的自动监测	Rodriguez Palomo, R.	PDF	N/A	Automatic surveillance of Escherichia coli bacteriological strains within clinical settings
单分子成像揭示了RNase E在埃希氏大肠杆菌中的定位和扩散过程中，膜结合基序和C端结构域的作用	Troyer, L.	PDF	N/A	Single-molecule imaging reveals the role of membrane-binding motif and C-terminal domain of RNase E in its localization and diffusion in Escherichia coli
直接脂质相互作用调控SARS-CoV-2 M蛋白的构象动态变化及病毒组装	Dutta, M.	PDF	N/A	Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly
疟原虫无性复制和热耐受性的关键作用依赖于HSP40	Roper, B.	PDF	N/A	Essential role for HSP40 in asexual replication and thermotolerance of malaria parasites
PgtE蛋白酶使致病性沙门氏菌能够逃避C3介导的血清和嗜中性粒细胞杀伤作用。	Lee, M. H.	PDF	N/A	PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing
大肠杆菌中的硫化物响应转录调控	Hori, K.	PDF	N/A	Sulfide-responsive transcription control in Escherichia coli
23S rRNA螺旋69的远端核糖2'-O-甲基化预先确定了核糖体亚基界面处的缠霉素药物结合口袋	Nandi, S.	PDF	N/A	Distant Ribose 2'-O-Methylation of 23S rRNA Helix 69 Pre-Orders the Capreomycin Drug Binding Pocket at the Ribosome Subunit Interface
铜绿假单胞菌必需基因扰动，使其在哺乳动物宿主环境中变得脆弱	Prasad, N. K.	PDF	N/A	Pseudomonas aeruginosa essential gene perturbations that confer vulnerability to the mammalian host environment
慢性分枝杆菌感染会引发巨噬细胞衰老。	Scarpa, E.	PDF	N/A	Chronic mycobacteria infection triggers macrophage senescence
原核生物抗病毒防御中利他主义的生态决定因素	Biba, D. A.	PDF	N/A	Ecological Determinants of Altruism in Prokaryote Antivirus Defense
比较RT-qPCR和qPCR揭示了柑橘黄龙病菌（Candidatus Liberibacter asiaticus）的早期感染、低拷贝感染以及相对细胞活性。	Patterson, R.	PDF	N/A	Comparative RT-qPCR and qPCR reveals early infection, low-titer infection, and relative cell activity of the HLB bacterium, Candidatus Liberibacter asiaticus
通过高速原子力显微镜直接观察亨廷顿蛋白淀粉样形成中的二次成核现象	van Ewijk, C.	PDF	N/A	Direct observation of secondary nucleation in huntingtin amyloid formation by High-Speed Atomic Force Microscopy
在不同发育阶段，本地适应的内陆一年生和沿海多年生生态型之间的基因表达差异	Olsen, J. D.	PDF	N/A	Gene expression divergence between locally adapted inland annual and coastal perennial ecotypes of Mimulus guttatus across developmental stages
改进的分裂质粒编辑器能够实现高效的体内基因编辑	Wei, R.	PDF	N/A	Improved split prime editors enable efficient in vivo genome editing
鞭毛内运输蛋白IFT172含有一个C端泛素结合的U型盒样结构域，参与纤毛信号传导。	Zacharia, N. K.	PDF	N/A	Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
Blm10的结构：13S蛋白酶体中间体揭示了蛋白酶体核心颗粒的并行组装途径	Kaur, M.	PDF	N/A	Structure of Blm10:13S proteasome intermediate reveals parallel assembly pathways for the proteasome core particle
缺乏多接头区域外限制位点的酿酒酵母极简整合穿梭载体	Scutteri, L.	PDF	N/A	Minimal integrating shuttle vectors for Saccharomyces cerevisiae depleted of restriction sites outside the polylinker region
谷氨酸棒杆菌系统代谢工程用于高效L-色氨酸生产	Dong, Y.	PDF	N/A	Systems metabolic engineering of Corynebacterium glutamicum for efficient L-tryptophan production
ITD对于（有偏差的）人类听觉方位感知是充分的	Azevedo, A. C. P. F. O. d.	PDF	N/A	Sufficiency of ITD for (biased) human auditory azimuthal perception
腹侧苍白球-伏隔核壳核通路的化学遗传学操控可调节雌性大鼠的蔗糖摄入，且与动机无关。	Peroutka, M. M.	PDF	N/A	Chemogenetic manipulation of the ventral pallidum-nucleus accumbens shell pathway modulates sucrose consumption independent of motivation in female rats.
Contactin-1 是周围神经网络结构的关键神经细胞表面受体。	Sinha, A.	PDF	N/A	Contactin-1 is a critical neuronal cell surface receptor for perineuronal net structure
特异性环状RNA circDS-1通过调控双态转变和毒力，促进塔罗霉菌（Talaromyces marneffei）的适应性进化	Hu, X.	PDF	N/A	Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition and virulence
多组学单细胞分析揭示了HIV-1早期感染中持续存在和宿主免疫反应异常的关键调控因子	Lee, D.	PDF	N/A	Multi-Omics Single-Cell Analysis Reveals Key Regulators of HIV-1 Persistence and Aberrant Host Immune Responses in Early Infection
金黄色葡萄球菌与铜绿假单胞菌之间的多微生物相互作用促进了生物膜的形成和在慢性伤口感染中的持久性。	Keim, K. C.	PDF	N/A	Polymicrobial interactions between Staphylococcus aureus and Pseudomonas aeruginosa promote biofilm formation and persistence in chronic wound infections
一种模型，源自脊髓损伤患者的混合物种尿道导管生物膜	Noorian, P.	PDF	N/A	A model, mixed-species urinary catheter biofilm derived from spinal cord injury patients
结构导向的突变分析揭示了小鼠胰岛素受体5'UTR IRES功能中一个关键的保守区域	Dahl, W. B.	PDF	N/A	Structure-informed mutagenesis identifies a conserved region critical for mouse insulin receptor 5'UTR IRES function
来自曲霉的疏水蛋白介导真菌与微塑料的相互作用	Klauer, R. R.	PDF	N/A	Hydrophobins from Aspergillus mediate fungal interactions with microplastics
大西洋鲑鱼对IPNV和ISAV病毒反应中宿主蛋白的不同泛素化	Stewart, R.	PDF	N/A	Differential Ubiquitination of Host Proteins in Response to IPNV and ISAV viruses in Atlantic salmon
维生素B12通过改善丙酸分解和一碳循环代谢途径，部分挽救了秀丽隐杆线虫Ephrin突变体胚胎细胞迁移缺陷。	Ganjawala, T. H.	PDF	N/A	Vitamin B12 partially rescues embryonic cell migration defects in C. elegans ephrin mutants by improving both propionic acid breakdown and one-carbon cycle metabolic pathways
气候和捕食压力驱动南非狒狒（Papio ursinus）昼夜活动模式的变异	Dzingwena, L.	PDF	N/A	Climate and predation drive variation of diel activity patterns in chacma baboons (Papio ursinus) across southern Africa
非尿素选择性GIRK通道激活剂的低剂量改善了由淀粉样β寡聚体破坏的海马依赖性突触可塑性和记忆	Mulero-Franco, J.	PDF	N/A	Low dose of a non-urea selective GIRK channel activator improves hippocampal-dependent synaptic plasticity and memory disrupted by amyloid-β oligomers
一种神经网络模型，能够在秀丽隐杆线虫中生成依赖于盐浓度记忆的趋化行为	Hironaka, M.	PDF	N/A	A neural network model that generates salt concentration memory-dependent chemotaxis in Caenorhabditis elegans
选择和结果的神经编码受到眶额皮层中不确定性的调节，但在次级运动皮层中则不受此影响。	Romero-Sosa, J. L.	PDF	N/A	Neural coding of choice and outcome are modulated by uncertainty in orbitofrontal but not secondary motor cortex
小胶质细胞通过胞外核苷酸酶CD39调节脑血流量和神经血管耦合	Fu, Z.	PDF	N/A	Microglia modulate cerebral blood flow and neurovascular coupling through ectonucleotidase CD39
HA1（一种普罗布考类似物）和ApoC3 siRNA对db/db小鼠脂蛋白-淀粉样蛋白代谢、神经血管完整性及认知功能的影响	Sharif, A.	PDF	N/A	Effects of HA1 (a Probucol Analogue) and ApoC3 siRNA on Lipoprotein-Amyloid Metabolism, Neurovascular Integrity and Cognitive Function in db/db Mice
尼古丁和吸烟暴露对发育期和成年期小鼠大脑的分子影响	Gonzalez-Padilla, D.	PDF	N/A	Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain
用于体外和体内神经应用的柔性3D剪纸探针	Jung, M.	PDF	N/A	Flexible 3D kirigami probes for in vitro and in vivo neural applications
口服Boldine可减轻小鼠神经损伤模型中的胶质细胞激活并预防神经性疼痛	Pan, J.	PDF	N/A	Oral Boldine Administration Attenuates Glia Activation and Prevents Neuropathic Pain in a Murine Spared Nerve Injury Model
线粒体功能障碍在帕金森病发病机制中损害核孔复合体	Riaz, Z.	PDF	N/A	Mitochondrial dysfunction Impairs the Nuclear Pore Complex in Parkinson's Disease Pathogenesis
通过GluN2C/GluN2D NMDA受体增强选择性增强中间神经元网络和伽马频段功率	Camp, C. R.	PDF	N/A	Selective Enhancement of the Interneuron Network and Gamma-Band Power via GluN2C/GluN2D NMDA Receptor Potentiation
DNA复制叉速度在皮质神经发生中起到引擎作用	Wang, J.	PDF	N/A	DNA replication fork speed Acts as an Engine in Cortical Neurogenesis
细胞类型特异性表观基因组编辑在发育中的小鼠皮层中促进中间前体细胞增殖，通过在lncSox1启动子区域靶向H3K9乙酰化	Sokpor, G.	PDF	N/A	Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex
跨物种神经解剖协变性别差异分析：人类与小鼠的研究	Pham, L.	PDF	N/A	A cross-species analysis of neuroanatomical covariance sex difference in humans and mice
空间单细胞图谱揭示了扣带-岛叶区域中神经元身份和兴奋性的关键调控因子	Fodoulian, L.	PDF	N/A	A spatial single-cell atlas of the claustro-insular region uncovers key regulators of neuronal identity and excitability
淀粉样蛋白-β抑制内皮细胞中β-连环蛋白信号通路，损害血管屏障完整性	Leasure, J. W.	PDF	N/A	Inhibition of β-catenin signaling by Amyloid-β in endothelial cells impairs vascular barrier integrity
在小鼠初级视觉皮层柱中，高效的层状分布相互作用和方向选择性	Zou, L.	PDF	N/A	Efficient laminar-distributed interactions and orientation selectivity in the mouse V1 cortical column
前注意转移不受扫视幅度的调节	Zimmermann Bortoluzzi, L.	PDF	N/A	Presaccadic attentional shifts are not modulated by saccade amplitude
解开眼球运动相关的耳膜振荡（EMREOs）：扫视方向和中耳特性如何塑造振幅和时间过程	Sotero Silva, N.	PDF	N/A	Unraveling eye movement-related eardrum oscillations (EMREOs): how saccade direction and middle ear properties shape amplitude and time course
通过多模态对比学习进行体内细胞类型和脑区分类	Yu, H.	PDF	N/A	In vivo cell-type and brain region classification via multimodal contrastive learning
一种依赖于CCDC112的新型精子中段形成和附睾成熟过程	O'Bryan, M. K.	PDF	N/A	A novel CCDC112-dependent process of sperm midpiece formation and epididymal maturation
化学感觉在果蝇中驱动不同的社会行为	Wu, B.	PDF	N/A	Chemosensation drives divergent social behavior in Drosophila
# BioRxiv 2024-11-04 Papers

标题	作者	PDF链接	代码仓库	Title
从头鉴定通用细胞力学基因特征	Urbanska, M.	PDF	N/A	De novo identification of universal cell mechanics gene signatures
异常的FGF信号促进SHH亚组婴儿型髓母细胞瘤中的颗粒神经元前体扩张	Yabut, O.	PDF	N/A	Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma
在单一种类的浮游植物病毒中，高生活史多样性	Lievens, E. J.	PDF	N/A	High life history diversity within a single genus of phytoplankton viruses
人类新皮层树突中信号传播速度的加快	Olah, G.	PDF	N/A	Accelerated signal propagation speed in human neocortical dendrites
HALO：用于单细胞多组学数据的层次因果建模	Mao, H.	PDF	N/A	HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data
对非生物胁迫的进化反应塑造了物种共存	Fragata, I.	PDF	N/A	Evolution in response to an abiotic stress shapes species coexistence
内体-溶酶体靶向纳米颗粒递送抗病毒疗法用于冠状病毒感染	Petcherski, A.	PDF	N/A	ENDO-LYSOSOME-TARGETED NANOPARTICLE DELIVERY OF ANTIVIRAL THERAPY FOR CORONAVIRUS INFECTIONS
在共享酶池中的催化生长确保了中心体大小的稳健控制。	Banerjee, D. S.	PDF	N/A	Catalytic growth in a shared enzyme pool ensures robust control of centrosome size
在由诱导多能干细胞衍生的神经元中进行的CRISPR筛选揭示了tau蛋白稳态的原理	Samelson, A. J.	PDF	N/A	CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
LrhA通过增强大肠杆菌中的预激活适应过程，促进了CRISPR-Cas免疫。	Fang, M.	PDF	N/A	LrhA promotes CRISPR-Cas immunity by enhancing primed adaptation in Escherichia coli
在一种世界性分布的植物谱系中，宏观进化推断出复杂的染色体物种形成模式	Tribble, C. M.	PDF	N/A	Macroevolutionary inference of complex modes of chromosomal speciation in a cosmopolitan plant lineage
基于进化扩散的蛋白质生成：序列即一切	Alamdari, S.	PDF	N/A	Protein generation with evolutionary diffusion: sequence is all you need
胺能和肽能对果蝇胰岛素产生细胞的调节作用	Held, M.	PDF	N/A	Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila
ElectroPhysiomeGAN：从记录的电生理响应生成生物物理神经元模型参数	Kim, J.	PDF	N/A	ElectroPhysiomeGAN: Generation of Biophysical Neuron Model Parameters from Recorded Electrophysiological Responses
神经纤毛蛋白-1通过旁分泌调控内皮粘附连接来控制血管通透性。	Pal, S.	PDF	N/A	Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
CausalXtract：一种从活细胞延时成像数据中提取因果效应的灵活管道	Simon, F.	PDF	N/A	CausalXtract: a flexible pipeline to extract causal effects from live-cell time-lapse imaging data
Pik3r1相关胰岛素抵抗的代谢保护性能量消耗增加并非由Ucp1介导的产热作用所解释。	Luijten, I.	PDF	N/A	The metabolically protective energy expenditure increase of Pik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis
脂质基纳米颗粒细胞周期和自噬相关细胞积累技术平台的构建与应用	Wang, Y.	PDF	N/A	Construction and application of a technical platform for determining cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles
基底前脑激活可改善老年猴子的工作记忆	Pennington, K. R.	PDF	N/A	Basal forebrain activation improves working memory in senescent monkeys
小鼠次级体感皮层和视觉皮层的注意调节	Petty, G.	PDF	N/A	Attentional modulation of secondary somatosensory and visual thalamus of mice
解决SARS-CoV-2系统发育中的大流行性系统错误	Hunt, M.	PDF	N/A	Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny
新生C57Bl/6小鼠循环中性粒细胞耗竭的方案	Mukherjee, D.	PDF	N/A	Protocols for circulating neutrophil depletion in neonatal C57Bl/6 mice
线粒体磷酸泛酰巯基乙胺化对于氧化功能是必需的。	Norden, P. R.	PDF	N/A	Mitochondrial Phosphopantetheinylation is Required for Oxidative Function
免疫耐受性的个体发育：早期生命分泌型IgA与肠道微生物群相互作用的模型	Tepekule, B.	PDF	N/A	The ontogeny of immune tolerance: a model of early-life secretory IgA - gut microbiome interactions
物体转移在大脑海马区引发事件编码	Duan, Y.-L.	PDF	N/A	Object-translocation induces event coding in the hippocampus
胃-脑耦合指数的增加标志着负面心理健康症状的维度特征。	Banellis, L.	PDF	N/A	Increased stomach-brain coupling indexes a dimensional signature of negative mental health symptoms.
叹息生成于前包钦格复合体	Cui, Y.	PDF	N/A	Sigh generation in preBötzinger Complex
CRF1受体的中断消除了吗啡诱导的雄性小鼠社交性缺陷及催产素能神经元的激活	Piccin, A.	PDF	N/A	Disruption of the CRF1 receptor eliminates morphine-induced sociability deficits and firing of oxytocinergic neurons in male mice
蚁群人口结构影响蚂蚁的巢穴建造	Rajendran, H.	PDF	N/A	Colony demographics shape nest construction in ants
多数LCL：基于标签对比学习和多数投票集成方法的疟疾细胞检测	Kundu, S.	PDF	N/A	Majority-LCL: Towards Malaria Cell Detection using Label Contrastive Learning and Majority voting Ensembling
从混乱的化学到生态学：在具有前生物合理性的化学系统中的自催化与遗传性	Sokolskyi, T.	PDF	N/A	From messy chemistry to ecology: autocatalysis and heritability in prebiotically plausible chemical systems
基于蛋白质语言的机器学习模型预测腺相关病毒适应性	Wu, J.	PDF	N/A	Prediction of Adeno-Associated Virus Fitness with a Protein Language Based Machine Learning Model
Wnt5a和Notum影响发育中气管软骨间充质凝集的时间动态。	Bottasso-Arias, N.	PDF	N/A	Wnt5a and Notum Influence the Temporal Dynamics of Cartilaginous Mesenchymal Condensations in Developing Trachea.
对来自加纳萨博巴区和博尔加坦加市的食物源性沙门氏菌和大肠杆菌分离株的基因组特征分析	Sunmonu, G. T.	PDF	N/A	Genomic characterization of foodborne Salmonella enterica and Escherichia coli isolates from Saboba district and Bolgatanga Municipality Ghana
探究他人的存在：跨脑尺度概率推断揭示增强的兴奋性突触效能	Esmaeili, A.	PDF	N/A	Probing other's Presence: Probabilistic Inference Across Brain Scales Reveals Enhanced Excitatory Synaptic Efficacy
探究视觉素养技能揭示了学生对染色体的意外认识	Uminski, C.	PDF	N/A	Probing visual literacy skills reveals unexpected student conceptions of chromosomes
视网膜拓扑编码组织了内部和外部导向的大脑网络之间的相互作用。	Steel, A.	PDF	N/A	Retinotopic coding organizes the interaction between internally and externally oriented brain networks
大麻烟和口服Δ9THC能增强老年受试者的工作记忆，但对年轻成年受试者则不然。	Zequeira, S.	PDF	N/A	Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects
针对蛋白水解的疫苗（PROTAVs）用于黑色素瘤的强效联合免疫治疗	Wang, Q.	PDF	N/A	Proteolysis-targeting vaccines (PROTAVs) for robust combination immunotherapy of melanoma
撤回：通过超快速生物过程减少一氧化二氮排放，实现高浓度N2O的去除	Maeda, R.	PDF	N/A	WITHDRAWN: Mitigating nitrous oxide emission by an ultra-fast bioprocess enabling the removal of high concentration N2O
乳腺上皮细胞命运转换的分子时间表	Vallmajo-Martin, Q.	PDF	N/A	The molecular chronology of mammary epithelial cell fate switching
利用肿瘤-免疫动力学综合模型预测慢性髓性白血病患者的无治疗缓解结果	Fassoni, A. C.	PDF	N/A	Predicting treatment-free remission outcomes in Chronic Myeloid Leukemia patients using an integrated model of tumor-immune dynamics
Dnajc3（HSP40）增强小鼠视神经的轴突再生	Wang, J.	PDF	N/A	Dnajc3 (HSP40) Enhances Axon Regeneration in the Mouse Optic Nerve
通过可逆的YAP和细胞因子控制细胞周期蛋白D1/p27比例的短暂增殖	Ferrick, K. R.	PDF	N/A	Transient proliferation by reversible YAP and mitogen-control of the cyclin D1/p27 ratio
自主神经和免疫应激反应网络在HIV感染者中的表现	Mueller, B. R.	PDF	N/A	Autonomic and Immune Stress Response Networks in Patients Living With HIV
H2O2 重新利用植物的氧气感应机制来控制对氧化应激的转录反应	Akter, S.	PDF	N/A	H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress
活体双光子荧光显微镜中神经场的自适应光学校正	Kang, I.	PDF	N/A	Adaptive optical correction for in vivo two-photon fluorescence microscopy with neural fields
鉴定环素L1作为调节乙型肝炎病毒复制的宿主因子	Owino, C. O.	PDF	N/A	Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replication
Foxi1通过转录和表观遗传机制调控粘液纤毛发育和离子细胞分化的多个步骤	Bowden, S.	PDF	N/A	Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms
听觉皮层中的正交频谱和时间包络表示	Takahashi, K.	PDF	N/A	Orthogonal spectral and temporal envelope representation in auditory cortex
FoldMark：通过水印技术保护蛋白质生成模型	ZHANG, Z.	PDF	N/A	FoldMark: Protecting Protein Generative Models with Watermarking
剪接因子激酶，即SR蛋白激酶1（SRPK1），对人类乳头瘤病毒生命周期中的晚期事件至关重要。	Faizo, A. A. A.	PDF	N/A	The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle.
空间转录组学揭示了生精上皮周期的时间结构及精确的Sertoli-生殖细胞同步化	Chakravorty, A.	PDF	N/A	Spatial Transcriptomics Reveals the Temporal Architecture of the Seminiferous Epithelial Cycle and Precise Sertoli-Germ Synchronization
稀疏动物社会网络分析	Mylne, H. K.	PDF	N/A	Analysis of sparse animal social networks
抑制鞭毛钩中赖氨酰丙氨酸交联的物质作为抗螺旋体微生物	Lynch, M. J.	PDF	N/A	Inhibitors of lysinoalanine crosslinking in the flagella hook as antimicrobials against spirochetes
在猴子前额叶和顶叶皮层中，3D BCI控制的伸手适应过程中，计划和运动活动在运动参考框架内共同适应。	Ferrea, E.	PDF	N/A	Planning and movement activities co-adapt in a motor-reference frame during 3D BCI-controlled reach adaptation in monkey frontal and parietal cortices
纹状体胆碱能中间神经元的同步激活诱导局部血清素释放	Matityahu, L.	PDF	N/A	Synchronous activation of striatal cholinergic interneurons induces local serotonin release
MethylGPT：一种用于DNA甲基化组的基模型	Ying, K.	PDF	N/A	MethylGPT: a foundation model for the DNA methylome
适应性峰值的反应规范追踪可能解释化石记录中的时间序列	Ergon, R.	PDF	N/A	Reaction norm tracking of fitness peaks may explain time series in the fossil record
超越体型二态性：Rensch法则的过去、现在与未来	Toyama, K. S.	PDF	N/A	Beyond size dimorphism: the past, present, and future of Rensch's Rule
基于Transformer的生存结果预测方法	Mellors, T.	PDF	N/A	A Transformer-Based Approach to Survival Outcome Prediction
叠加的人动脉内皮细胞产生动脉粥样硬化的脂质条纹并释放促炎性细胞因子	Zeng, Y.	PDF	N/A	Stacked Human Arterial Endothelial Cells Generate Atherosclerotic Fatty Streaks and Release Proinflammatory Cytokines
汽车尾气中的PM2.5通过ROS-UPRmt信号通路诱导雄性大鼠生殖细胞凋亡	Wang, C.	PDF	N/A	PM2.5 from Automobile Exhaust Induces Apoptosis in Male Rat Germ Cells via the ROS-UPRmt Signaling Pathway
休眠繁殖体库在塑造群落构建的生态进化动力学中的作用	Lin, J.	PDF	N/A	The role of dormant propagule banks in shaping eco-evolutionary dynamics of community assembly
长期低流量和非本地鱼类共同作用，改变了山区溪流中昆虫的羽化过程。	Evangelista, C.	PDF	N/A	Prolonged low flows and non-native fish operate additively to alter insect emergence in mountain streams
多态性串联重复序列塑造了免疫景观中单细胞基因表达的多样性	Tanudisastro, H. A.	PDF	N/A	Polymorphic tandem repeats shape single-cell gene expression across the immune landscape
药物输送过程模拟 - 量化紫杉醇和聚氧乙烯蓖麻油（Cremophor EL）的构象动力学	Uddin, M.	PDF	N/A	Drug Delivery Process Simulation - Quantifying the Conformation Dynamics of Paclitaxel and Cremophor EL
利用Halbach阵列和磁性纳米颗粒控制人诱导多能干细胞心肌细胞工程组织中的机电波	Pozo, M. R.	PDF	N/A	Control of electromechanical waves in engineered tissue of human iPSC-cardiomyocytes using a Halbach array and magnetic nanoparticles
通过软体机器人动态刺激实现生物打印组织可编程三维细胞排列	Rosalia, L.	PDF	N/A	Programmable 3D cell alignment of bioprinted tissue via soft robotic dynamic stimulation
学习具有多输出高斯过程的单细胞多组学数据的解释性表示	Moslehi, Z.	PDF	N/A	Learning interpretable representations of single-cell multi-omics data with multi-output Gaussian Processes
强化身份赋予癌细胞癌症特征	Yang, H.	PDF	N/A	Reinforced identity confers cells with cancer hallmarks
肿瘤缺氧性细胞外囊泡为三阴性乳腺癌创造了一个保护性微环境	Pachane, B. C.	PDF	N/A	Tumoral hypoxic extracellular vesicles create a protective microenvironment for triple-negative breast cancer
使用维替泊芬抑制Yes相关蛋白（YAP）通过诱导G2M停滞和抑制DNA损伤反应增强脊索瘤的放射敏感性	Akinduro, O. O.	PDF	N/A	Inhibition of Yes-Associated Protein (YAP) with Verteporfin Enhances Radiosensitivity in Chordoma by Inducing G2M Arrest and Inhibiting the DNA Damage Response
结合不可逆和可逆药物抗性机制的个性化癌症治疗策略	He, W.	PDF	N/A	Personalized cancer treatment strategies incorporating irreversible and reversible drug resistance mechanisms
具有偏置记忆模式的Hopfield神经网络的鲁棒性	Montazeri, A.	PDF	N/A	Robustness in Hopfield neural networks with biased memory patterns
一种来自恒河的新型Pbunavirus噬菌体通过下调las/rhl系统及减少KPC碳青霉烯酶，在多重耐药铜绿假单胞菌的废水生物控制中发挥作用。	Samson, R.	PDF	N/A	A novel Pbunavirus phage from the Ganges River in biocontrol of multidrug-resistant Pseudomonas aeruginosa in wastewater by downregulation of las/rhl systems and reduction of KPC carbapenemases
延迟反馈对基于规则和信息整合类别学习的影响。	Edmunds, C. E. R.	PDF	N/A	The effect of deferring feedback on rule-based and information-integration category learning.
人类诱导多能干细胞的扰动细胞图谱	Nourreddine, S.	PDF	N/A	A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS
人类诱导多能干细胞的扰动细胞图谱	Nourreddine, S.	PDF	N/A	A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS
基于转录组学的FCRL6作为糖尿病肾病新型诊断生物标志物的鉴定	Marinedrive, A.	PDF	N/A	Transcriptomic-Based Identification of FCRL6 as a Novel Diagnostic Biomarker in Diabetic Nephropathy
口咽癌复发与肿瘤内在及免疫介导的基因组不稳定性降低的后果相关联	Sannigrahi, M. K.	PDF	N/A	Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability
内吞作用通过减弱与BMP信号通路平行的Highwire/PHR1依赖性JNK信号传导，限制了突触的生长。	Pippadpally, S.	PDF	N/A	Endocytosis restricts synapse growth by attenuating Highwire/PHR1-dependent JNK signaling in a pathway parallel to the BMP signaling
肠道神经元scRNA-seq的青少年和成人元图谱：用于数据集比较和肠道神经元亚型转录组定义的共识	Benthal, J. T.	PDF	N/A	Meta-atlas of Juvenile and Adult Enteric Neuron scRNA-seq for Dataset Comparisons and Consensus on Transcriptomic Definitions of Enteric Neuron Subtypes
智力和认知灵活性有选择地调节工作记忆功能	Zhang, H.	PDF	N/A	Intelligence and Cognitive Flexibility Selectively Modulate Working Memory Functioning
归一化动态时间规整提高了区分精神分裂症功能网络连接的敏感性	Wiafe, S.-L.	PDF	N/A	Normalized Dynamic Time Warping Increases Sensitivity In Differentiating Functional Network Connectivity In Schizophrenia
精神病障碍中孤独感与海马对动态社交刺激反应之间的关联	McKenna, F.	PDF	N/A	Association between loneliness and hippocampal responses to dynamic social stimuli in psychotic disorders
样本特异性网络分析识别出晚期肾癌免疫治疗反应的基因共表达模式	Yin, L.	PDF	N/A	Sample-specific network analysis identifies gene coexpression patterns of immunotherapy response in advanced kidney cancer
肿瘤浸润淋巴细胞显示出与三阴性乳腺癌患者化疗反应相关的预后特征	Banerjee, S.	PDF	N/A	Tumor-Infiltrating Lymphocytes Display Prognostic Signatures Associated with Chemotherapy Response in TNBC Patients
在急性和慢性感染中表征低密度中性粒细胞基因特征及其对疾病严重程度的影响	de Toledo, M. A.	PDF	N/A	Characterizing a Low-Density Neutrophil gene signature in acute and chronic infections and its impact on disease severity
新皮质第4层神经元对阿尔茨海默病抗性的分子特征	Dharshini, S. A. P.	PDF	N/A	Molecular Signatures of Resilience to Alzheimer's Disease in Neocortical Layer 4 Neurons
视觉引导的补偿机制减轻聋哑引起的歌声退化	Rolland, M.	PDF	N/A	Visually-guided compensation of deafening-induced song deterioration
为维持生产力而设计的条带耕作增加了地面甲虫的生物多样性。	Croijmans, L.	PDF	N/A	Strip cropping designed for maintaining productivity increases ground beetle biodiversity
如何通过部分表型测定来缩短世代间隔，从而帮助提高选育蜜蜂种群的年遗传增益	Kistler, T.	PDF	N/A	How partial phenotyping to reduce generation intervals can help to increase annual genetic gain in selected honeybee populations
识别和注释着丝粒低甲基化区域与着丝粒双峰区域（CDR）查找器	Mastrorosa, F. K.	PDF	N/A	Identification and annotation of centromeric hypomethylated regions with Centromere Dip Region (CDR)-Finder
通过X射线晶体学鉴定电压门控钠通道中对挥发性麻醉剂具有功能重要性的结合位点	Hollingworth, D.	PDF	N/A	Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography
将连续经验整合到深度生成网络中可以解释人类记忆、预测和规划	Spens, E.	PDF	N/A	Consolidation of sequential experience into a deep generative network explains human memory, prediction and planning
ASD相关的CNTNAP2变异体通过受损的胞外域脱落调控破坏神经元树突发育	Lobete, M.	PDF	N/A	ASD-ASSOCIATED CNTNAP2 VARIANTS DISRUPT NEURONAL ARBORIZATION THROUGH IMPAIRED REGULATION BY ECTODOMAIN SHEDDING
蝇舞迪斯科：用于光遗传学和精细蝇类行为分析的硬件与软件	Robie, A. A.	PDF	N/A	The Fly Disco: Hardware and software for optogenetics and fine-grained fly behavior analysis
年龄和淀粉样β依赖性神经纤维缠结的启动：一种改进的阿尔茨海默病小鼠模型，不涉及MAPT基因突变。	Desai, S.	PDF	N/A	Age and amyloidβ-dependent initiation of neurofibrillary tau tangles: an improved mouse model of Alzheimers disease without mutations in MAPT.
伏隔核D2表达神经元：通过节律性光遗传刺激平衡奖励与舔舐中断	Requejo-Mendoza, N.	PDF	N/A	Nucleus accumbens D2-expressing neurons: Balancing reward and licking disruption through rhythmic optogenetic stimulation
在雄性大鼠中，微胶质细胞的药理学耗竭可防止酒精中毒期间皮质边缘系统的神经退行性变。	Carlson, E. R.	PDF	N/A	Pharmacological depletion of microglia protects against alcohol-induced corticolimbic neurodegeneration during intoxication in male rats
一种全球性的多巴胺能学习率使得在众多选项中能够进行适应性的觅食行为。	Grima, L. L.	PDF	N/A	A global dopaminergic learning rate enables adaptive foraging across many options
MINT：一个用于分析多元神经信息编码和传输的工具箱	Lorenz, G. M.	PDF	N/A	MINT: a toolbox for the analysis of multivariate neural information coding and transmission
重复磁刺激通过协同的前后突触活动诱导兴奋性突触的可塑性。	Galanis, C.	PDF	N/A	Repetitive magnetic stimulation induces plasticity of excitatory synapses through cooperative pre- and postsynaptic activity.
F2,6BP恢复亨廷顿病中线粒体基因组的完整性	Chakraborty, A.	PDF	N/A	F2,6BP restores mitochondrial genome integrity in Huntingtons Disease
用于磁旋转图的体积导体模型	O'Neill, G. C.	PDF	N/A	Volume conductor models for magnetospinography
耳蜗神经树突长度中的蜗轴-支柱梯度：动态范围中一种新的突触后贡献？	Kostrikov, S.	PDF	N/A	A modiolar-pillar gradient in auditory-nerve dendritic length: a novel post-synaptic contribution to dynamic range?
在伸手过程中，大脑广泛区域的活动整合了由动作介导的目标预期。	Peng, Y.	PDF	N/A	Brain-wide population activity during reaching integrates action-mediated goal expectation
光流解析作为因果源分离：一种从光流中同时提取物体和自运动信息的计算模型	Scherff, M.	PDF	N/A	Flow parsing as causal source separation: A computational model for concurrent retrieval of object and self-motion information from optic flow
通过NrCAM和Ankyrin B，胆囊收缩素-篮状中间神经元对胞体突触的靶向作用	Oldre, E. N.	PDF	N/A	Perisomatic Synaptic Targeting by Cholecystokinin-Basket Interneurons through NrCAM and Ankyrin B
机械负荷使血影蛋白网络发生“连续”蛋白水解，并促进神经退行性变的早期发作。	Malaiwong, N.	PDF	N/A	Mechanical load conditions the spectrin network to `run-on' proteolysis and promotes early onset neurodegeneration
人类枕颞皮层中视网膜定位偏差和类别选择性的系统性效应	Silson, E. H.	PDF	N/A	Systematic effects of retinotopic biases and category selectivity across human occipitotemporal cortex
使用控制理论方法从钙成像预测神经元放电	Rondoni, N.	PDF	N/A	Predicting neuronal firing from calcium imaging using a control theoretic approach
使用控制理论方法从钙成像预测神经元放电	Rondoni, N.	PDF	N/A	Predicting neuronal firing from calcium imaging using a control theoretic approach
在小鼠原代皮层神经元的多组学分析中揭示了积雪草成分化合物之间复杂的正负生物相互作用	Chamberlin, S. R.	PDF	N/A	Multi-omics analysis in mouse primary cortical neurons reveals complex positive and negative biological interactions between constituent compounds in Centella asiatica
通过益生菌和维生素D孕期补充调节产前氯吡硫磷暴露的神经毒性作用：对神经发育和社会性的意外影响	Ruiz Coca, M.	PDF	N/A	Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability
dArc1调控果蝇糖奖励的评价	Caron, S. J. C.	PDF	N/A	dArc1 controls sugar reward valuation in Drosophila melanogaster
嵌合音乐揭示了音乐编码的电生理特征中音高与时间之间的相互作用	Shan, T.	PDF	N/A	Chimeric music reveals an interaction of pitch and time in electrophysiological signatures of music encoding
通过转录抑制和直接CAG重复结合抑制亨廷顿病体细胞不稳定性	Mathews, E. W.	PDF	N/A	Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding
细菌效应因子筛选揭示RNF214为哺乳动物中的病毒限制因子	Embry, A.	PDF	N/A	Bacterial Effector Screening Reveals RNF214 as a Virus Restriction Factor in Mammals
猴痘/mpox病毒对细胞坏死和I型干扰素反应的调控。	Williams, J.	PDF	N/A	Regulation of Necroptosis and the Type Interferon Response by Monkeypox/mpox Virus.
急性三氯生暴露改变非洲爪蟾蝌蚪的线粒体形态和功能，包括正在发育的大脑	Thomson, A. H.	PDF	N/A	Acute Triclosan Exposure Alters Mitochondrial Form and Function in Xenopus laevis Tadpoles, Including the Developing Brain
精子发生波的自组织协调了小鼠睾丸中持续的精子生成	Sato, T.	PDF	N/A	Self-organization of spermatogenic wave coordinates sustained sperm production in the mouse testis
依托咪酯作为安乐死成年斑马鱼（Danio Rerio）的有效替代方法	Schwartz, K.	PDF	N/A	Etomidate as an Effective Alternative Method of Euthanizing Adult Zebrafish (Danio Rerio)
两组分信号网络中激酶和效应子信号逻辑的变化	Swingle, D.	PDF	N/A	Variations in kinase and effector signaling logic in a two component signaling network
核小体中DNA聚合酶β进行缺口填充DNA合成的结构基础	Weaver, T. M.	PDF	N/A	Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β
设计的小蛋白能有效抑制并防御中东呼吸综合征冠状病毒（MERS-CoV）	Ragotte, R. J.	PDF	N/A	Designed miniproteins potently inhibit and protect against MERS-CoV
谱系检测器：高效检测新SARS-Cov-2谱系的工具	Zou, X.	PDF	N/A	Lineage Detector: Efficient Tool for Detecting New SARS-Cov-2 Lineages
机器学习设计的PoLixNano纳米颗粒克服了雾化mRNA疗法的递送障碍	Zhang, D.	PDF	N/A	Machine learning engineered PoLixNano nanoparticles overcome delivery barriers for nebulized mRNA therapeutics
利用噬菌体展示技术进行合理工程化，以获得更高亲和力的人源化3-磷酸组胺酸特异性抗体	Martyn, G. D.	PDF	N/A	Using phage display for rational engineering of a higher affinity humanized 3-phosphohistidine-specific antibody
PreciCE：通过数据驱动的多基因控制转录网络实现细胞命运的精密工程	Magnusson, J. P.	PDF	N/A	PreciCE: Precision engineering of cell fates via data-driven multi-gene control of transcriptional networks
大规模抗菌活性调查揭示了健康皮肤微生物群中的新型防御物种	Nguyen, U. T.	PDF	N/A	Large-scale investigation for antimicrobial activity reveals novel defensive species across the healthy skin microbiome
韦伯病毒是一类感染克雷伯氏菌属的肠道相关噬菌体。	Dawson, S. J.	PDF	N/A	Weberviruses are gut-associated phages that infect Klebsiella spp.
来自产气荚膜梭菌（Clostridium perfringens）的生物膜基质蛋白通过IV型菌毛相关分泌机制形成分子间异肽键	Kivimaki, S. E.	PDF	N/A	Type IV pili-associated secretion of a biofilm matrix protein from Clostridium perfringens that forms intermolecular isopeptide bonds
人类JC病毒的染色质模拟	Schaefer, U.	PDF	N/A	Chromatin mimicry by human JC virus
食品安全细菌动力学的空间特征：共享水处理环境的建模	Munther, D.	PDF	N/A	Spatial characterizations of bacterial dynamics for food safety: Modeling for shared water processing environments
鉴定新型噻唑衍生物作为登革病毒和日本脑炎病毒蛋白酶抑制剂	Murtuja, S.	PDF	N/A	Identification of novel thiazole derivatives as flaviviral protease inhibitors against DENV and JEV
作为微生物群落中的一种觅食策略的对抗作用	Stubbusch, A. K. M.	PDF	N/A	Antagonism as a foraging strategy in microbial communities
微生物在钴胺素偏好上表现出广泛的多样性。	Mok, K. C.	PDF	N/A	Microbes display broad diversity in cobamide preferences
有氧碳代谢通过调节亚硝酸盐氨化菌以抑制氮素流失——基于旱地农田土壤微宇宙实验的揭示	Wu, X.	PDF	N/A	Aerobic carbon metabolism modulates nitrite ammonifiers for inhibiting nitrogen loss as revealed by microcosm experiment of agricultural upland soil
H3K4me3甲基转移酶KMT2F通过促进RNA聚合酶I的启动前复合物形成来调控核糖体RNA转录。	Lone, K.	PDF	N/A	H3K4me3 methyltransferase KMT2F promotes pre-initiation complex formation by RNA Polymerase I to regulate ribosomal RNA transcription.
衰老和感染中补体途径和丝氨酸蛋白酶抑制剂激活的时空转录组生态位	Kern, F.	PDF	N/A	Spatiotemporal transcriptomic niches of complement pathway and serine protease inhibitor activation in aging and infection
利用合成细胞间信号实现分割钟的同步	Isomura, A.	PDF	N/A	Synchronization of the segmentation clock using synthetic cell-cell signaling
非性腺PIWI蛋白Aubergine调控果蝇成肠中再生干细胞的增殖与肿瘤发生。	Bellec, K.	PDF	N/A	Non-gonadal PIWI protein, Aubergine, regulates regenerative stem cell proliferation and tumourigenesis in the Drosophila adult intestine.
通过反向激动纳米体揭示的非典型趋化因子受体的组成活性	Perez Almeria, C. V.	PDF	N/A	Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies
使用AlphaFold2对变构蛋白进行结构分析	Tyree, S.	PDF	N/A	Structural Analysis of a Metamorphic Protein using AlphaFold2
TRPC1和TRPC5异源四聚体的冷冻电镜结构	Chen, Y.	PDF	N/A	The Cryo-EM structure of TRPC1 and TRPC5 heterotetramer
药用植物金莲花基因组序列揭示了黄酮类生物合成的见解	Friedhoff, R.	PDF	N/A	Genome sequence of the medicinal plant Tropaeolum majus provides insights into flavonoid biosynthesis
抗原特异性T细胞受体发现用于治疗进行性多灶性白质脑病	Gupta, S.	PDF	N/A	Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy
验证DXS作为分枝杆菌中一个有吸引力的药物靶点	Mashabela, G. T.	PDF	N/A	Validation of DXS as an attractive drug target in mycobacteria
东部马脑炎病毒E2糖蛋白上的三个正电荷结合位点协同介导了依赖于硫酸乙酰肝素和蛋白受体的感染过程。	Alcorn, M. D. H.	PDF	N/A	Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection
预测性元组学：微生物组研究中多组学数据稀缺的潜在解决方案	Cosma, B. M.	PDF	N/A	Predicted meta-omics: a potential solution to multi-omics data scarcity in microbiome studies
机会性病原体广泛存在于在乳制品设施捕获的稳定蝇的可培养外源性和内源性微生物群中。	Sommer, A. J.	PDF	N/A	Opportunistic pathogens are prevalent across the culturable exogenous and endogenous microbiota of stable flies captured at a dairy facility
从不同环境样本中鉴定新型FosX家族决定因素	Kieffer, N.	PDF	N/A	Identification of Novel FosX Family Determinants from Diverse Environmental Samples
高分辨率分析负责CCR5内吞作用的arrestin2相互作用	Petrovic, I.	PDF	N/A	A high-resolution analysis of arrestin2 interactions responsible for CCR5 endocytosis
开放-封闭模最小化算法	Groot Koerkamp, R.	PDF	N/A	The open-closed mod-minimizer algorithm
全基因组范围内对RPA1和RAD9的映射揭示了利什曼原虫中多顺反子转录、复制起始及复制应激反应的管理机制	Black, J. A.	PDF	N/A	Genome-wide mapping of RPA1 and RAD9 reveals the management of polycistronic transcription, replication initiation, and responses to replication stress in Leishmania
# BioRxiv 2024-11-03 Papers

标题	作者	PDF链接	代码仓库	Title
多能干细胞的多谱系分化图谱揭示了TMEM88作为哺乳动物血压发育调节因子的作用	Shen, S.	PDF	N/A	A pluripotent stem cell atlas of multilineage differentiation reveals TMEM88 as a developmental regulator of mammalian blood pressure
进化上多样化的穴样内陷蛋白共享一个围绕两亲性盘状结构构建的共同结构框架	Han, B.	PDF	N/A	Evolutionarily diverse caveolins share a common structural framework built around amphipathic discs
利用神经风格迁移研究动物信号设计的演变：以一种装饰性鱼类为例	Hejja-Brichard, Y.	PDF	N/A	Using Neural Style Transfer to study the evolution of animal signal design: A case study in an ornamented fish
动粒蛋白KNL-1调控肌动蛋白细胞骨架以控制树突分支	Domingos, H. A.	PDF	N/A	The Kinetochore Protein KNL-1 Regulates the Actin Cytoskeleton to Control Dendrite Branching
图拉普拉斯谱、拓扑性质以及结构脑网络的高阶相互作用具有个体特异性、可重复性，但高度依赖于图构建方案。	Dimitriadis, S. I.	PDF	N/A	Graph Laplacian Spectrum, topological properties, and high-order interactions of Structural Brain Networks are Subject-Specific, Repeatable but Highly Dependent on Graph Construction Scheme
从足月人胎盘中发现的多能细胞类型	Vadakke-Madathil, S.	PDF	N/A	Discovery of a multipotent cell type from the term human placenta
利用动态因果推断识别促进癌症进展的合作基因	Cifuentes Bernal, A.	PDF	N/A	Identifying cooperative genes causing cancer progression with dynamic causal inference
神经纤毛蛋白-1通过旁分泌调节内皮粘附连接来控制血管通透性	Pal, S.	PDF	N/A	Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
用于肝毒性检测的再生人肝类器官（HLOs）在柱状/灌流板中	Shrestha, S.	PDF	N/A	Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays
演变为混沌——传播性与免疫逃逸之间权衡的含义	Sayyar, G.	PDF	N/A	Evolution into chaos - implications of the trade-off between transmissibility and immune evasion
蛋白质序列和结构的标记化和连续嵌入压缩	Lu, A. X.	PDF	N/A	Tokenized and Continuous Embedding Compressions of Protein Sequence and Structure
异戊二烯通过启动植物激素反应来驱避植食性昆虫。	Sahu, A.	PDF	N/A	Isoprene deters insect herbivory by priming plant hormone responses
从共进化动态耦合的图分析中提取的功能重要残基	Xu, M.	PDF	N/A	Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings
酵母线粒体中COX1 mRNA翻译激活机制的深入研究	Zamudio-Ochoa, A.	PDF	N/A	Insights into the Translational Activation Mechanisms of the COX1 mRNA in Yeast Mitochondria
Clytia的口面细胞类型与珊瑚幼虫具有共同特征，并将牛磺酸与定殖的调控联系起来。	Ramon-Mateu, J.	PDF	N/A	Aboral cell types of Clytia and coral larvae have shared features and link taurine to the regulation of settlement
通过体内mRNA递送实现抗原特异性T细胞免疫疗法	Su, F.-Y.	PDF	N/A	Antigen-specific T cell immunotherapy by in vivo mRNA delivery
蛋白质亚细胞定位预测的深度生成模型	Yang, L.	PDF	N/A	Deep generative model for protein subcellular localization prediction
蛋白质亚细胞定位预测的深度生成模型	Yuan, G.-H.	PDF	N/A	Deep generative model for protein subcellular localization prediction
使用Pythia-PPI可靠地预测蛋白质-蛋白质结合亲和力在突变后的变化	Tao, F.	PDF	N/A	Reliable prediction of protein-protein binding affinity changes upon mutations with Pythia-PPI
畸变校正拼接器：集成光学畸变校正的显微图像拼接	Cang, H.	PDF	N/A	DistortCorrect Stitcher: Microscopy Image Stitching with Integrated Optical Distortion Correction
RvD1 和 LXA4 对心脏电压门控钾通道的抑制作用	de la Cruz, A.	PDF	N/A	RvD1 and LXA4 inhibitory effects on cardiac voltage-gated potassium channels
具有高级基因组特征的自我认证基因组材料	Wang, Z.	PDF	N/A	Self-Authenticating Genomic Materials with Advanced Genome Signatures
沙门氏菌效应蛋白SseL通过β-连环蛋白信号轴诱导PD-L1上调和T细胞失活	Chopra, U.	PDF	N/A	Salmonella effector SseL induces PD-L1 up-regulation and T cell inactivation via beta-catenin signalling axis
SloR-SRE与S. mutans mntH启动子的结合具有协同性。	Ziogas, M.	PDF	N/A	SloR-SRE binding to the S. mutans mntH promoter is cooperative.
一种高通量蛋白质标记工具包，保留了内源性UTR，用于研究动质体中的基因调控。	Carbajo, C. G.	PDF	N/A	A high-throughput protein tagging toolkit that retains endogenous UTRs for studying gene regulation in Kinetoplastids.
牙形石牙齿基质蛋白1指导石鳖牙齿中的氧化铁沉积	Nemoto, M.	PDF	N/A	Radular teeth matrix protein 1 directs iron oxide deposition in chiton teeth
小鼠粗线期piRNA切割数百个转录本，但仅改变少数靶标的稳态丰度	Cecchini, K.	PDF	N/A	Mouse Pachytene piRNAs Cleave Hundreds of Transcripts,But Alter the Steady-State Abundance of Only a Minority of Targets
CELF2通过铰链域介导的核凝聚促进tau外显子10的包含	Li, X.	PDF	N/A	CELF2 promotes tau exon 10 inclusion via hinge domain-mediated nuclear condensation
秋水仙碱抑制小鼠平滑肌细胞表型转换及主动脉夹层	Jiang, H.	PDF	N/A	Colchicine Inhibits Smooth Muscle Cell Phenotypic Switch and Aortic Dissection in Mice
发育中的小鼠腭单细胞图谱揭示了表皮细胞命运的细胞和分子转变	Huang, W.	PDF	N/A	Single-cell atlas of developing mouse palates reveals cellular and molecular transitions in periderm cell fate
CCR9信号终止受一种不依赖于arrestin的磷酸化机制调控。	Lamme, T. D.	PDF	N/A	CCR9 signal termination is governed by an arrestin-independent phosphorylation mechanism
模拟膜热蛋白质组分析（MM-TPP）用于绘制膜蛋白-配体动力学图谱	Jandu, R. S.	PDF	N/A	Membrane mimetic thermal proteome profiling (MM-TPP) towards mapping membrane protein-ligand dynamics
通过生化重建揭示的DNA复制叉稳定和重启机制	Canal, B.	PDF	N/A	DNA replication fork stabilization and restart mechanisms revealed by biochemical reconstitution
通过增强Wnt/β-catenin信号通路和下调TGF-β/Samd/BMP信号通路，硝酸盐促进C57BL/6小鼠毛发生长	Lan, Y.	PDF	N/A	Nitrate Promoting Hair Growth Through Enhancing Wnt/β-catenin and Downregulating TGF-β/Samd/BMP signaling pathway in C57BL/6 Mice
一种评估癌症多药耐药性的定量方法	Ray, A. E.	PDF	N/A	A Quantitative Approach for Assessing Multidrug Resistance in Cancer
使用工程化重组酶将特定DNA插入人类基因组	Fanton, A.	PDF	N/A	Site-specific DNA insertion into the human genome with engineered recombinases
BC-设计：一种高精度逆蛋白质折叠的生物化学感知框架	Tang, X.	PDF	N/A	BC-Design: A Biochemistry-Aware Framework for High-Precision Inverse Protein Folding
衰老生物标志物的公开竞赛	Ying, K.	PDF	N/A	An Open Competition for Biomarkers of Aging
代谢调控RNA甲基化由m6A阅读器IGF2BP3介导	Sharma, G.	PDF	N/A	Metabolic regulation of RNA methylation by the m6A-reader IGF2BP3
核仁中前rRNA的空间分布与功能组织	Pan, Y.-H.	PDF	N/A	Pre-rRNA spatial distribution and functional organization of the nucleolus
由HSF1调控的蛋白质稳态网络增强的显性负性TP53突变	Sebastian, R. M.	PDF	N/A	Dominant-negative TP53 mutations potentiated by the HSF1-regulatedproteostasis network
纽蛋白Y822磷酸化调控心肌细胞粘附动力学及心脏中粘着连接的成熟过程	Li, X.	PDF	N/A	Vinculin Y822 phosphorylation regulates cardiomyocyte adhesion dynamics and adherens junction maturation in the heart
PNPLA3-I148M是一种新形态，干扰了两种主要的肝甘油三酯清除途径。	Sherman, D. J.	PDF	N/A	PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
资源波动下多物种共存的一个统一原则	Richardson, J. A.	PDF	N/A	A unifying principle for multispecies coexistence under resource fluctuations
PreDigs：一个针对消化细胞注释的特定上下文细胞类型标记和精确细胞亚型的数据库	Meng, J.	PDF	N/A	PreDigs: a Database of Context-specific Cell-type Markers and Precise cell subtypes for Digestive Cell Annotation
长读长纳米孔全基因组eDNA测序用于河流生物多样性、污染和环境健康监测	Nousias, O.	PDF	N/A	Long-read nanopore shotgun eDNA sequencing for river biodiversity, pollution and environmental health monitoring
将铁氧还蛋白-NADP+还原酶连接到光系统I上促进了光合循环电子传递	Emrich-Mills, T. Z.	PDF	N/A	Tethering ferredoxin-NADP+ reductase to photosystem I promotes photosynthetic cyclic electron transfer
核篮的解离会引发衰老酵母中的染色体丢失	Mirkovic, M.	PDF	N/A	Dissociation of the nuclear basket triggers chromosome loss in aging yeast
剪接体成分GAMETOPHYTIC FACTOR 1（GFA1）调控关键的光周期转换	Tiedemann, S.	PDF	N/A	The spliceosomal component GAMETOPHYTIC FACTOR 1 (GFA1) regulates a key photoperiodic switch
开发一种用于EV定量的ELISA检测方法，以辅助大规模EV生产	Zhou, X.	PDF	N/A	Development of an ELISA assay for EV quantification to assist the large-scale EV manufacture
微生物组使N-酰基脂质池多样化——包括由短链脂肪酸衍生的化合物。	Mannochio-Russo, H.	PDF	N/A	The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds
血小板在早期腹主动脉瘤形成中具有保护作用	Russell, H. M.	PDF	N/A	Platelets are Protective in Early Abdominal Aortic Aneurysm Formation
高温下植物亚细胞碳水化合物代谢	Seydel, C.	PDF	N/A	Subcellular plant carbohydrate metabolism under elevated temperature
叶黄素循环在海水藻类Nannochloropsis oceanica中平衡了光保护与光合效率	Michelberger, T.	PDF	N/A	The Xanthophyll Cycle balances Photoprotection and Efficiency in the seawater alga Nannochloropsis oceanica
许多转录因子家族在植物中具有进化上保守的结合基序	Zenker, S.	PDF	N/A	Many transcription factor families have evolutionarily conserved binding motifs in plants
A型和C型响应调节基因对水稻生长和穗部结构有积极影响	Rong, C.	PDF	N/A	Positive impact of Type-A and -C response regulator genes on growth and panicle architecture in rice
一种新型顺铂类前药抑制赖氨酸去乙酰化酶，抑制核苷酸切除修复，并克服耐药性	Negev Korem, Y.	PDF	N/A	A Novel Cisplatin-Based Prodrug Inhibits Lysine Deacetylases, Suppresses Nucleotide Excision Repair, and Overcomes Resistance
草莓（Fragaria x ananassa）中抗疫霉菌2（RPc2）位点的基因组结构	Han, H.	PDF	N/A	Genomic Architecture of the Resistance to Phytophthora Cactorum 2 (RPc2) Locus in Strawberry (Fragaria x ananassa)
草莓（Fragaria x ananassa）中抗疫霉菌2（RPc2）位点的基因组结构	Han, H.	PDF	N/A	Genomic Architecture of the Resistance to Phytophthora Cactorum 2 (RPc2) Locus in Strawberry (Fragaria x ananassa)
肾小管上皮细胞中的DNA损伤反应需要nephronophthisis蛋白GLIS2/NPHP7	Ebert, L. K.	PDF	N/A	The nephronophthisis protein GLIS2/NPHP7 is required for the DNA damage response in kidney tubular epithelial cells
肠道干细胞通过凋亡小体吞噬作用增强局部黏膜免疫	Zhou, J. Y.	PDF	N/A	Intestinal stem cells enhance local mucosal immunity through apoptotic body phagocytosis
半合成铁蛋白纳米笼用于灵活、位点特异性靶向、簇形成及膜受体激活	Neusch, A.	PDF	N/A	Semisynthetic Ferritin Nanocages for Flexible, Site-specific Targeting, Cluster-formation and Activation of Membrane Receptors
人类细胞中依赖于检查点的DNA复制叉稳定机制	Bertolin, A. P.	PDF	N/A	The mechanism of checkpoint-dependent DNA replication fork stabilization in human cells
突触间隙的几何结构通过调节神经递质停留时间来影响NMDAR开放概率	Hernandez Mesa, M.	PDF	N/A	Synaptic cleft geometry modulates NMDAR opening probability by tuning neurotransmitter residence time
一种协调的激酶和磷酸酶网络调控Stu2招募至酵母动粒	Stewart, M. G.	PDF	N/A	A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores
在3D BCI控制的伸手适应过程中，猴子的前额叶和顶叶皮层中的运动参考框架内的计划和运动活动共同适应	Ferrea, E.	PDF	N/A	Planning and movement activities co-adapt in a motor-reference frame during 3D BCI-controlled reach adaptation in monkey frontal and parietal cortices
两种视觉运动适应的学习方式	Zhang, Y.	PDF	N/A	Two ways to learn in visuomotor adaptation
抑制α7 nAChR活性在脆性X综合征小鼠模型中导致听源性癫痫发作和过度活跃	Goebel, S.	PDF	N/A	Dampened α7 nAChR activity contributes to audiogenic seizures and hyperactivity in a mouse model of Fragile X Syndrome
研究在轻微足底电击应激后，基因标记的杏仁核神经元中c-Fos的变化	Dong, H.	PDF	N/A	Investigate c-Fos changes in genetically identified amygdala neurons after mild footshock stress
CX3CR1-BAC-Cre的组成型表达在微胶质细胞中引入最小的脱靶效应	Mroue-Ruiz, F. H.	PDF	N/A	Constitutive expression of CX3CR1-BAC-Cre introduces minimal off-target effects in microglia
产前接触δ-9-四氢大麻酚对小鼠大脑发育的影响：一项从胎儿到成年的磁共振成像研究	Cupo, L.	PDF	N/A	Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study
睡眠中断改善了简单嗅觉和视觉决策任务中的表现	Pflitsch, P.	PDF	N/A	Sleep Disruption Improves Performance in Simple Olfactory and Visual Decision-Making Tasks
策略优化源于噪声表示学习	Brenner, J. W.	PDF	N/A	Policy optimization emerges from noisy representation learning
快速眼动睡眠在海马体中记忆的神经分化过程中所起的作用	McDevitt, E. A.	PDF	N/A	The role of REM sleep in neural differentiation of memories in the hippocampus
轻度局部冷却可选择性地影响树突树中的计算过程	Matin, M. H.	PDF	N/A	Mild focal cooling selectively impacts computations in dendritic trees
计算建模显示了支持意识的感觉和前额叶理论的证据。	Bandara, K. H.	PDF	N/A	Computational modelling shows evidence in support of both sensory and frontal theories of consciousness
关于心智游移和动态思维的神经基础：一项药物和脑刺激研究	Rasmussen, T.	PDF	N/A	On the neural substrates of mind wandering and dynamic thought: A drug and brain stimulation study
外侧缰核中的神经元-星形胶质细胞耦合介导了抑郁样行为	Xin, Q.	PDF	N/A	Neuron-astrocyte Coupling in Lateral Habenula Mediates Depressive-like Behaviors
一种双向的脑-脂肪体轴用于病原体规避	Wang, Y.	PDF	N/A	A Bidirectional Brain-Fat Body Axis for Pathogen Avoidance
新生儿脑室内出血后侧脑室纤毛功能障碍不会导致基于纤毛的脑脊液流动网络的功能变化。	Pan, S.	PDF	N/A	Cilia dysfunction in the lateral ventricles after neonatal intraventricular hemorrhage does not lead to functional changes in cilia-based CSF flow networks
锥体细胞类型和5-HT2A受体对于赛洛西宾持久药效的发挥至关重要	Shao, L.-X.	PDF	N/A	Pyramidal cell types and 5-HT2A receptors are essential for psilocybin's lasting drug action
睾丸中体细胞性别认同的转变会引发体细胞中雌性特异性的细胞行为，并在生殖细胞中诱导早期卵母细胞的特化。	Roach, T. V.	PDF	N/A	Conversion of somatic sex identity in the testis induces female-specific cellular behaviors in the soma and early oocyte specification in the germline
量化生物模式形成的复杂性：通过复杂性度量的新视角	Riedel, J. H. R.	PDF	N/A	Quantifying the intricacies of biological pattern formation: A new perspective through complexity measures
长寿保障基因LAG1和LAC1在调节酿酒酵母内质网应激和脂质稳态中的不同作用	MATHIVANAN, A.	PDF	N/A	Differential Roles of Longevity Assurance Genes LAG1 and LAC1 in Regulating Endoplasmic Reticulum stress and Lipid Homeostasis in Saccharomyces cerevisiae
相分离解决与生长相关的电路故障	Zhang, R.	PDF	N/A	Phase Separation to Resolve Growth-Related Circuit Failures
高通量开发和表征用于人细胞基因调控和表观遗传控制的新型功能性纳米抗体	Wan, J.	PDF	N/A	High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells
纹状体胆碱能中间神经元的同步激活可诱导局部血清素释放	Matityahu, L.	PDF	N/A	Synchronous activation of striatal cholinergic interneurons induces local serotonin release
小鼠血吸虫病中的血小板减少症与肝脏巨噬细胞摄取血小板有关，这些巨噬细胞具有独特的激活表型。	Greenman, J. H.	PDF	N/A	Thrombocytopenia in murine schistosomiasis is associated with platelet uptake by liver macrophages that have a distinct activation phenotype
神经毒性和非神经毒性HIV-1菌株及其Tat蛋白诱导不同的细胞因子-趋化因子谱	Rao, V. R.	PDF	N/A	Neurovirulent and non-neurovirulent strains of HIV-1 and their Tat proteins induce differential cytokine-chemokine profiles
评估鞋类作为媒介传播意外感染源给小鼠的生物安全风险	Palillo, M. B.	PDF	N/A	Assessing the Biosecurity Risk of Footwear as a Fomite for Transmission of Adventitious Infectious Agents to Mice
在感染过程中，巨噬细胞会产生一种名为甲基乙二醛的抗菌效应分子。	Anaya-Sanchez, A.	PDF	N/A	Methylglyoxal is an antibacterial effector produced by macrophages during infection
Progerin的积累导致了Hutchinson-Gilford早衰综合征中主动脉平滑肌细胞的丧失	Kim, P. H.	PDF	N/A	The Accumulation of Progerin Underlies the Loss of Aortic Smooth Muscle Cells in Hutchinson-Gilford Progeria Syndrome
慢性压力会阻碍应激颗粒的形成	Adachi, Y.	PDF	N/A	Chronic stress antagonizes formation of Stress Granules
解释不同分类水平上土壤细菌群落结构的非生物和生物因素的相对影响	Mayjonade, B.	PDF	N/A	The relative effects of abiotic and biotic factors in explaining the structure of soil bacterial communities at diverse taxonomic levels
同域分布的Stichopus cf. horrens（棘皮动物门：刺参科）种群基因组分化：基于SNP标记对生殖隔离的见解	Kim, K. M.	PDF	N/A	Genomic divergence of sympatric lineages within Stichopus cf. horrens (Echinodermata: Stichopodidae): Insights on reproductive isolation inferred from SNP markers
野生鸟类中的卵激素是否具有适应性后果？一项系统综述与元分析	Mentesana, L.	PDF	N/A	Do egg hormones have fitness consequences in wild birds? A systematic review and meta-analysis
物种共存性在占用模型中能被可靠地推断出来吗？	Louvrier, J.	PDF	N/A	How reliably can species co-occurrence be inferred from occupancy models?
FIGNL1通过解离RAD51纤维，在BRCA2缺陷细胞中抑制同源重组	Kuthethur, R.	PDF	N/A	FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments
使用原始模板定向扩增技术对胚泡活检标本进行精确的全外显子组分析	Samitova, A.	PDF	N/A	PRECISE EXOME ANALYSIS OF BLASTOCYST BIOPSY SCALE SAMPLES USING PRIMARY TEMPLATE-DIRECTED AMPLIFICATION
将编码变异等位基因系列测试扩展到汇总统计数据	McCaw, Z. R.	PDF	N/A	Extending the Coding-variant Allelic Series Test to Summary Statistics
JNK的阈值水平通过JAK/STAT激活损伤响应增强子，促进组织再生	Quinn, J. W.	PDF	N/A	A threshold level of JNK activates damage-responsive enhancers via JAK/STAT to promote tissue regeneration
细菌工程活体材料调节哺乳动物细胞的力学信号传导	Ostmann, K.	PDF	N/A	Bacterial Engineered Living Materials modulate Mechanosignaling in Mammalian Cells
使用isONclust3对大规模长读长转录组数据进行从头聚类	Petri, A. J.	PDF	N/A	De novo clustering of extensive long-read transcriptome datasets with isONclust3
MARVEL：通过监督图对比学习进行微环境注释	CUI, Y.	PDF	N/A	MARVEL: Microenvironment Annotation by Supervised Graph Contrastive Learning
通过热点引导的生成式深度学习进行类药物PPI抑制剂的靶向设计	Sun, H.	PDF	N/A	Target-specific design of drug-like PPI inhibitors via hot-spot-guided generative deep learning
drMD：面向实验学家的分子动力学	Shrimpton-Phoenix, E.	PDF	N/A	drMD: Molecular Dynamics for Experimentalists
Kaizen：使用VQ-VAE分解细胞图像	Majoral, D.	PDF	N/A	Kaizen: Decomposing cellular images with VQ-VAE
使用机器学习预测延长小鼠寿命的化学化合物	Belikov, A. V.	PDF	N/A	Predicting Mouse Lifespan-Extending Chemical Compounds with Machine Learning
多上下文种子能够实现快速且高精度的读取映射	Tolstoganov, I.	PDF	N/A	Multi-context seeds enable fast and high-accuracy read mapping
IPMN的空间转录组学揭示了不同惰性和恶性谱系	Iyer, M. K.	PDF	N/A	Spatial Transcriptomics of IPMN Reveals Divergent Indolent and Malignant Lineages
TACSTD2表达标志着结肠腺瘤的早期转变	Siskova, A.	PDF	N/A	TACSTD2 expression marks the early transition to colon adenomas
使用CSI-TME识别IDH突变型胶质瘤肿瘤微环境中具有预后意义的细胞状态相互作用	Singh, A.	PDF	N/A	Identifying Prognostic Cell State Interactions in the TumorMicroenvironment of IDH-Mutant Gliomas Using CSI-TME
单细胞AML图谱揭示了t(8;21) AML中与年龄相关的基因调控网络	Whittle, J.	PDF	N/A	Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML
在一组新型的EGFR酪氨酸激酶抑制剂适应性非小细胞肺癌细胞系中的表型可塑性	Nanthaprakash, T.	PDF	N/A	Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor-adapted non-small cell lung cancer cell lines
外源性ephrin-A3给药恢复了孕激素处理小鼠的阴道上皮屏障功能	Liu, M.	PDF	N/A	Exogenous ephrin-A3 administration restores vaginal epithelial barrier function in progestin-treated mice
金雕定期利用重力波在阿尔卑斯山翱翔：高分辨率气象数据带来的新见解	Carrard, T.	PDF	N/A	Golden eagles regularly use gravity waves to soar in the Alps: new insights from high-resolution weather data
巢或不巢：印度奥里萨邦橄榄海龟大规模筑巢事件的环境提示	Srikanthan, P.	PDF	N/A	To nest or not to nest: environmental cues for olive ridley mass nesting events in Odisha, India
一种简易且经济高效的微流控装置，采用三维交叉流T型接头生成脱细胞的细胞外基质衍生微载体	Kamar, F.	PDF	N/A	A simple, cost-effective microfluidic device using a 3D cross-flow T-junction for producing decellularized extracellular matrix-derived microcarriers
基于聚酮合成的多元醇、氨基醇和羟基酸生物合成平台	Dan, Q.	PDF	N/A	A polyketide-based biosynthetic platform for diols, amino alcohols and hydroxyacids
HMGB1介导了巨噬细胞的招募，并在损伤后导致区域性椎间盘组织的生理和力学特性发生改变。	Burt, K. G.	PDF	N/A	HMGB1 mediates macrophage recruitment and regional intervertebral disc tissue functional and mechanical property changes following injury.
BLOC：可构建和可连接的芯片上器官	Kimura, Y.	PDF	N/A	BLOC: buildable and linkable organ on a chip
从多能干细胞中可调的人CD4+和CD8+ T细胞的差异化	Jones, R. D.	PDF	N/A	Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells
综合无偏分析加速动脉粥样硬化中血管组织变化的高分辨率超声结合光声成像技术	de Jong, A.	PDF	N/A	Comprehensive Unbiased Analysis of Vascular Tissue Changes in Accelerated Atherosclerosis Using High-Resolution Ultrasound combined with Photoacoustic Imaging
GeneCover：一种无标签标记基因选择的组合方法	Wang, A.	PDF	N/A	GeneCover: A Combinatorial Approach for Label-free Marker Gene Selection
从超级字符串到索引：利用掩码Burrows-Wheeler变换（MBWT）为无约束k-mer集合构建空间高效索引	Sladky, O.	PDF	N/A	FroM Superstring to Indexing: a space-efficient index for unconstrained k-mer sets using the Masked Burrows-Wheeler Transform (MBWT)
通过单细胞和空间转录组学在轻度IgA肾病肾小球内皮细胞中鉴定的炎症分子	Hasegawa, K.	PDF	N/A	Inflammatory molecules in the glomerular endothelium in mild IgA-Nephropathy identified by single-cell and spatial transcriptome
cOmicsArt - 一个可定制的组学分析与报告工具	Seep, L.	PDF	N/A	cOmicsArt - a customizable Omics Analysis and reporting tool
病理学中人工智能模型的反事实扩散模型用于机制可解释性	Zigutyte, L.	PDF	N/A	Counterfactual Diffusion Models for Mechanistic Explainability of Artificial Intelligence Models in Pathology
在连锁不平衡不匹配的情况下进行稳健的精细定位	Zhang, W.	PDF	N/A	Robust fine-mapping in the presence of linkage disequilibrium mismatch
多组学分析揭示了CMTR1在癌症中的上调及其在核糖体蛋白基因表达和肿瘤生长中的作用	Campeanu, I. J.	PDF	N/A	Multi-omics analysis reveals CMTR1 upregulation in cancer and roles in ribosomal protein gene expression and tumor growth
一种新型体外AML骨髓微环境模型揭示CD44和粘着斑激酶为逆转细胞粘附介导的药物抵抗的治疗靶点	Ladikou, E. E.	PDF	N/A	A novel in-vitro model of the bone marrow microenvironment in AML identifies CD44 and Focal Adhesion Kinase as therapeutic targets to reverse cell adhesion-mediated drug resistance
关键的分析参数有助于在从组织中提取的RNA中自信地检测表达变化、融合和短变异	Kubik, S.	PDF	N/A	Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue
选择具有高生产潜力且对黑果病（BPR）和霜冻果病（FPR）具有耐受性的可可克隆品种。	Lopez, M.	PDF	N/A	Selecting cacao clones with high productivity potential and tolerance to Black Pod Rot (BPR) and Frosty Pod Rot (FPR).
人类肾小球中拓扑结构不同但功能等效的多条出球小动脉	Li, J. J. X.	PDF	N/A	Topologically distinct and equivalent multiple efferent arterioles in the human glomeruli
山鸡椒叶甲醇粗提物在动物模型中对抗氧化应激、血栓形成、炎症及大便频率的影响	Arifuzzaman, S.	PDF	N/A	Methanol Crude Extract of Litsea Monopetala Leaves combats oxidative stress, clot formation, inflammation and stool frequency in Animal Model
慢性给予氟乙基诺美胺（FENM）在小鼠阿尔茨海默病模型中的神经保护作用	Carles, A.	PDF	N/A	Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease
转录组分析揭示了尼达尼布治疗在大鼠博来霉素模型中与脂质代谢和巨噬细胞参与相关的机制	Bonatti, M.	PDF	N/A	Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model
比较Ocimum gratissimum和Jatropha tanjorensis的抗氧化活性 2024。	Ike, E. C.	PDF	N/A	Comparative antioxidant activity of Ocimum gratissimum and Jatropha tanjorensis 2024.
计算机模拟靶向磷酸二酯酶5及阿赞那加果的催情效果体内评估	Ejiofor, I. I.	PDF	N/A	In-silico Targeting Phosphodiesterase 5 and In-vivo Evaluation of the Aphrodisiac Effect of Azanza garckeana Fruit
真菌毒素白色念珠菌素在肠道芯片模型中破坏上皮屏障完整性并引发炎症	Morelli, M.	PDF	N/A	Mycotoxin candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model
发现和分离新型辣椒素及其与TRPV1相关活性	Smith, J.	PDF	N/A	Discovery and isolation of novel capsaicinoids and their TRPV1-related activity
环境相关铅暴露对SH-SY5Y细胞在整个神经元分化过程中的基因表达产生影响	Morgan, R. K.	PDF	N/A	Environmentally Relevant Lead Exposure Impacts Gene Expression in SH-SY5Y Cells Throughout Neuronal Differentiation
REDD1是决定肾细胞癌对自噬抑制敏感性的一个因素，通过靶向PIM激酶活性可以实现治疗利用。	Carew, J. S.	PDF	N/A	REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM kinase activity
经皮迷走神经刺激可减轻创伤后骨关节炎小鼠模型的疼痛和病情进展	Yadav, S.	PDF	N/A	Transcutaneous Vagus Nerve Stimulation Reduces Pain and OA Progression in Mouse Models of Post-Traumatic Osteoarthritis
ATGL介导的脂解作用对肌细胞线粒体功能至关重要，并能增强PPARδ诱导的线粒体呼吸功能的改善。	Gemmink, A.	PDF	N/A	ATGL-mediated lipolysis is essential for myocellular mitochondrial function and augments PPARδ-induced improvements in mitochondrial respiration
LPS与志贺毒素暴露对培养的人脐静脉内皮细胞RNA表达程序的协同作用。	Svilar, D.	PDF	N/A	Synergy of LPS and Shiga-toxin exposure on the RNA expression program of cultured human umbilical vein endothelial cells.
真空干燥的公羊精子在室温下保存四年后，其生育力得以保存。	Moncada, M.	PDF	N/A	Fertility Preservation of Vacuum-Dried Ram Spermatozoa Stored for Four Years at Room Temperature
番茄果实中碳代谢的组织特异性响应对低氧胁迫的反应	Li, X.	PDF	N/A	Tissue-specific responses of the central carbon metabolism in tomato fruit to low oxygen stress
在耐寒的蟋蟀Gryllus veletis中，HSP70在热应激后上调，但在冷冻应激后并未上调。	Adams, V. E.	PDF	N/A	HSP70 is upregulated after heat but not freezing stress in the freeze-tolerant cricket Gryllus veletis
蜜蜂对饮食中长期存在的酒精具有抵抗力。	Ostap-Chec, M.	PDF	N/A	Honey bees are resilient to the long-term presence of alcohol in their diet
豚鼠胎盘hIGF1纳米颗粒基因治疗以胎儿性别特异性的方式改善了胎儿生长受限相关的肝脏脂质和葡萄糖代谢相关信号通路的变化。	Davenport, B. N.	PDF	N/A	Placental hIGF1 nanoparticle gene therapy in guinea pigs ameliorates fetal growth restriction-associated changes in hepatic lipid and glucose metabolism-related signaling pathways in a fetal sex-specific manner
使用Nav1.5的N端片段进行基因治疗以治疗心脏通道病：一种增强心脏钠电流的新型反式互补机制	Gizon, M.	PDF	N/A	Gene Therapy with the N-terminal Fragment of Nav1.5 for Cardiac Channelopathies: A Novel Transcomplementation Mechanism Potentiating the Cardiac Sodium Current
COSMOS：社区与单微生物优化系统	Raajaraam, L.	PDF	N/A	COSMOS: COmmunity and Single Microbe Optimisation System
通过同步给药方案来调控癌症免疫周期	Newton, P. K.	PDF	N/A	Gaming the cancer-immunity cycle by synchronizing the dose schedules
MethylGPT：一种用于DNA甲基化组的基础模型	Ying, K.	PDF	N/A	MethylGPT: a foundation model for the DNA methylome
预测在MetaCyc知识库中注释的代谢物参与的代谢途径	Huckvale, E. D.	PDF	N/A	Predicting the pathway involvement of metabolites annotated in the MetaCyc knowledgebase
C3-C3aR轴调节肺泡巨噬细胞的训练免疫	Earhart, A. P.	PDF	N/A	The C3-C3aR axis modulates trained immunity in alveolar macrophages
雷帕霉素增强CAR-T细胞在体内控制HIV复制和清除储藏库的作用。	Zhen, A.	PDF	N/A	Rapamycin Enhances CAR-T Control of HIV Replication and Reservoir Elimination in vivo.
KDM6A介导的基因组不稳定性和代谢重编程的丧失，在膀胱癌中对免疫检查点治疗和化疗的反应存在差异性调控。	Singh, P.	PDF	N/A	Loss of KDM6A-mediated genomic instability and metabolic reprogramming differentially regulates responses to immune checkpoint therapy and chemotherapy in bladder cancer.
抗原流动性调节B细胞免疫突触中抗原捕获的动力学和精确性	McArthur, H. C. W.	PDF	N/A	Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse
综合应激反应促进巨噬细胞在自身免疫性糖尿病中的炎症和迁移	Wang, J. E.	PDF	N/A	The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes
儿童骨髓的单细胞多组学研究揭示了与基质细胞异质性相关的年龄依赖性谱系分化差异	Hanemaaijer, E. S.	PDF	N/A	Single-cell multiomics of pediatric BM reveals age-dependent differences in lineage differentiation linked to stromal cell heterogeneity
基底膜水凝胶抑制CAR-T细胞激活：纳米纤维素凝胶作为替代品以在三维细胞培养中保持T细胞功能。	Revilla, S. A.	PDF	N/A	Basement membrane hydrogels dampen CAR-T cell activation: nanofibrillar cellulose gels as alternative to preserve T cell function in 3D cell cultures.
利用血液单细胞转录组学整合内在和系统性免疫衰老	Tomusiak, A.	PDF	N/A	Utilizing blood single-cell transcriptomics to integrate intrinsic and systemic immune aging
弓形虫感染脑炎模型中不同CD8记忆T细胞亚群	Moretto, M. M.	PDF	N/A	Divergent CD8 memory T cell subsets in an encephalitis model of Toxoplasma gondii infection
揭示外分泌腺中由ILC2衍生的GM-CSF维持的独特巨噬细胞群体	Westermann, F.	PDF	N/A	Unveiling a unique macrophage population in exocrine glands sustained by ILC2-derived GM-CSF
脂肪来源基质细胞与人及大鼠胰岛共培养的分泌组分析揭示了具有增强再生能力的特征	Pinheiro-Machado, E.	PDF	N/A	Secretome analysis of human and rat pancreatic islets co-cultured with adipose-derived stromal cells reveals a signature with enhanced regenerative capacities
TET2介导的表观遗传修饰促进2型糖尿病中胰腺β细胞的压力性衰老	Cai, W.	PDF	N/A	TET2-mediated epigenetic modification promotes stress senescence of pancreatic β cells in type 2 diabetes mellitus
通过培养条件调节脂肪来源基质细胞的分泌组：对血管生成、胶原沉积和免疫调节的影响。	Pinheiro-Machado, E.	PDF	N/A	Modulating adipose-derived stromal cells' secretomes by culture conditions: effects on angiogenesis, collagen deposition, and immunomodulation.
纤维化肝脏疾病中蛋白质毒性应激的蛋白质组学图谱	Rosenberger, F. A.	PDF	N/A	The proteomic landscape of proteotoxic stress in a fibrogenic liver disease
微管正端动力学与MOR1聚合酶的周转过程紧密耦合。	Eng, R. C.	PDF	N/A	Microtubule plus-end dynamics are tightly coupled to the turnover of the MOR1 polymerase
人类苦味受体在人类主动脉和冠状动脉内皮细胞中的表达谱	Kochany, P.	PDF	N/A	Expression Profile of Human Bitter Taste Receptors in Human Aortic and Coronary Artery Endothelial Cells
等渗介质处理可限制烧伤伤口微生物定植，并促进组织修复。	Horn, A.	PDF	N/A	Isotonic medium treatment limits burn wound microbial colonization and improves tissue repair
利用慢性胰腺炎患者来源的类器官模型鉴定分子和功能亚型	Osorio-Vasquez, V.	PDF	N/A	Identification of molecular and functional subtypes using chronic pancreatitis patient-derived organoid models
使用开源软件对全切片脂肪组织图像进行高通量脂肪细胞大小测量	Ramalho, A. C.	PDF	N/A	High-throughput measurement of adipocyte size with open-source software using whole-slide adipose tissue images
BBS/CCT伴侣蛋白复合物确保粘附性G蛋白偶联受体ADGRV1定位于初级纤毛	Linnert, J.	PDF	N/A	The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to primary cilia
免疫抑制药物对内皮细胞功能表现出不同的影响。	Elezaby, A.	PDF	N/A	Immunosuppression Drugs Exhibit Differential Effects on Endothelial Cell Function
H2S 重塑线粒体超微结构并破坏呼吸超级复合体	Hanna, D. A.	PDF	N/A	H2S remodels mitochondrial ultrastructure and destabilizes respiratory supercomplexes
一项细胞生物学研究揭示了卵菌效应子运输机制的新见解	Tomczynska, I.	PDF	N/A	A CELL BIOLOGY STUDY REVEALS NEW INSIGHTS INTO THE TRANSPORT MECHANISMS OF OOMYCETE EFFECTORS
核糖核苷酸还原酶的细胞质定位对于基因组稳定性至关重要	Andreadis, C.	PDF	N/A	Cytoplasmic localization of ribonucleotide reductase is essential for genome stability
多组学揭示了伤口床微环境分泌信号对巨噬细胞的年龄依赖性代谢重编程	Forni, M. F.	PDF	N/A	Multiomics reveals age-dependent metabolic reprogramming of macrophages by wound bed niche secreted signals
增强人类诱导多能干细胞的冷冻保存：自下而上与传统冷冻几何形状	Teodoro, F.	PDF	N/A	Enhancing cryopreservation of human iPSCs: Bottom-up vs Conventional freezing geometry
景观复杂性的生态记忆塑造了淡水群落的多样性。	Tabi, A.	PDF	N/A	The ecological memory of landscape complexity shapes diversity of freshwater communities
量化猎物在避免鸟类捕食者攻击中，隐蔽、警戒和逃避策略的成功率	Linke, D.	PDF	N/A	Quantifying the success of prey crypsis, aposematism and evasiveness in avoiding avian predators attack
在鸟类属中，源振幅随着体重的增加而增加。	Ziegenhorn, M. A.	PDF	N/A	Source amplitude increases with body mass across avian genera
首次尝试使用性标记SSM4和ALLWSex2对长期保存的东北美短吻鲟（Acipenser brevirostrum）血液样本进行多重PCR验证。	Pozveh, H. S. T.	PDF	N/A	First attempt to validate multiplex PCR with sex markers SSM4 and ALLWSex2 in long-term stored blood samples of eastern North American shortnose sturgeon (Acipenser brevirostrum).
利用时空子采样建模美洲隼下降情况以提高eBird数据可靠性	Sharma, A.	PDF	N/A	Modeling American Kestrel Decline Using Spatiotemporal Subsampling to Improve eBird Data Reliability
环境DNA揭示了干旱地区临时水体中无脊椎动物群落的时间和空间变异性	Hedges, B. A.	PDF	N/A	Environmental DNA reveals temporal and spatial variability of invertebrate communities in arid-lands ephemeral water bodies
气候变化对物种生态位概念及分布的影响	Berti, E.	PDF	N/A	The impacts of climate variability on the niche concept and distributions of species
蜘蛛为理解节肢动物体型变异和性二型性的生态进化驱动因素提供了新的见解。	Ameline, C.	PDF	N/A	Spiders bring new insight into the eco-evolutionary drivers of body size variation and sexual size dimorphism in arthropods
全骨鱼类基因组揭示了脊椎动物免疫蛋白酶体的进化新奇性，这对MHCI功能具有重要意义。	Barker, A. V.	PDF	N/A	Holostean genomes reveal evolutionary novelty in the vertebrate immunoproteasome that have implications for MHCI function
综合分析CAM光合作用揭示其对丝兰初级代谢的影响	Wickell, D. A.	PDF	N/A	Integrative analysis of CAM photosynthesis reveals its impact on primary metabolism in Yucca
尤卡坦半岛咸水洞穴中海绵（多孔动物门，普通海绵纲）的物种多样性与线粒体DNA分析	Suarez-Moo, P. d. J.	PDF	N/A	Species Diversity and Mitochondrial DNA Analysis of Sponges (Porifera, Demospongiae) in an Anchialine Cave on the Yucatan Peninsula
在慈鲷鱼快速适应辐射过程中的环形物种形成平行案例	Gautier, G.	PDF	N/A	Parallel cases of ring speciation within a rapid adaptive radiation of cichlid fishes
基因表达和花粉表现表明，在具有不同交配系统的茄属物种之间，交配后选择发生了改变。	Biewer-Heisler, T. J.	PDF	N/A	Gene expression and pollen performance indicate altered postmating selection between Solanum species with different mating systems
欺骗者在合作持久性中的关键作用	Babajanyan, S.	PDF	N/A	The key role of cheaters in the persistence of cooperation
英国欧洲貂种群历史性人口下降的特征	Shaw, R. L.	PDF	N/A	Characterisation of the historic demographic decline of the British European polecat population
病毒和细胞蛋白质组结构域中内在无序性的演变	Mughal, F.	PDF	N/A	Evolution of intrinsic disorder in the structural domains of viral and cellular proteomes
适应性峰值的反应规范追踪可能解释化石记录中的时间序列	Ergon, R.	PDF	N/A	Reaction norm tracking of fitness peaks may explain time series in the fossil record
有害藻华形成性浮游藻类中的泛基因组生物学与进化	Sibbald, S. J.	PDF	N/A	Pangenome biology and evolution in harmful algal-bloom-forming pelagophyte algae
超越体型二态性：Rensch法则的过去、现在与未来	Toyama, K. S.	PDF	N/A	Beyond size dimorphism: the past, present, and future of Rensch's Rule
用于豹（Panthera pardus）非侵入性基因分型的SNP面板	Spong, G.	PDF	N/A	SNP panel for non-invasive genotyping of leopard (Panthera pardus)
同义密码子使用定义功能基因家族	Ghanegolmohammadi, F.	PDF	N/A	Synonymous codon usage defines functional gene families
辣椒（Capsicum annum L.）耐热性遗传多样性分析	Usmani, S. F.	PDF	N/A	Genetic Diversity Analysis for Heat Stress Tolerance in Chili (Capsicum annum L.)
研究R3HCC1L在胚胎发育和眼科疾病中可能的作用	Fischer, M. C.	PDF	N/A	Investigating a possible role of R3HCC1L in embryonic development and ocular disease
具有MYT1L杂合突变的小鼠寿命	Schreiber, A.	PDF	N/A	Lifespan in rodents with MYT1L heterozygous mutation
JG2：日本人群特异性参考基因组的更新版本	Sriwichaiin, S.	PDF	N/A	JG2: an updated version of the Japanese population-specific reference genome
StableLift：优化跨基因组构建的种系和体细胞变异检测	Wang, N. K.	PDF	N/A	StableLift: Optimized Germline and Somatic Variant Detection Across Genome Builds
表观遗传沉默和宿主基因组进化决定了病毒插入在棘阿米巴中的命运	Blais, C.	PDF	N/A	Epigenetic silencing and host genome evolution determine fate of viral insertions in Acanthamoeba
新兴的特比萘芬耐药性毛癣菌的基因组流行病学	Rhodes, J.	PDF	N/A	Genomic epidemiology of emerging terbinafine-resistant Trichophyton indotineae
一种用于造血祖细胞和干细胞靶向的模块化逐层纳米颗粒平台	Dacoba, T. G.	PDF	N/A	A Modular Layer-by-Layer Nanoparticle Platform for Hematopoietic Progenitor and Stem Cell Targeting
主肺动脉的构成性神经网络：发现未被发现的部分	Vervenne, T.	PDF	N/A	Constitutive neural networks for main pulmonary arteries: Discovering the undiscovered
使用氨基酸进行蛋白质分类的混合Transformer与神经网络配置	Labiosa, N.	PDF	N/A	Hybrid Transformer and Neural NetworkConfiguration for Protein Classification UsingAmino Acids
低压等容冷冻作为一种可扩展技术用于新鲜食品保存	Maida, A.	PDF	N/A	Low-pressure Isochoric Freezing as a scalable technique for fresh food preservation
重构mRNA脂质纳米颗粒以实现向胰腺的全身递送	Isaac, I.	PDF	N/A	Reengineering mRNA lipid nanoparticles for systemic delivery to pancreas
体外骨骼肌构建物的三维生物打印用生物墨水的开发与表征	Kado Abdalkader, R.	PDF	N/A	Development and characterization of bioinks for 3D bioprinting of in vitro skeletal muscle constructs
基于低RT的鼠肝细胞基因组编辑保真性：挑战与解决方案	Dunyak, M. T.	PDF	N/A	Low RT-based Genome Editing Fidelity in Mouse Hepatocytes: Challenges and Solutions
通过非内体途径向免疫细胞体外递送mRNA，无需进行核苷修饰。	Ghoshal, B.	PDF	N/A	Ex Vivo Delivery of mRNA to Immune Cells Via a Non-Endosomal Route Obviates the Need for Nucleoside Modification
免疫学比较：改良小鼠子宫内纤维化模型中菌株与诱导方法的差异	Hernandez, J. L.	PDF	N/A	Immunologic comparisons of strain and induction method in an improved mouse model of intrauterine fibrosis
在无意中不当处理婴儿时的高重力加速度：对婴儿摇晃综合征诊断的影响	Lee-Confer, J. S.	PDF	N/A	High G-Forces in Unintentionally Improper Infant Handling: Implications for Shaken Baby Syndrome Diagnosis
基于肌肉的生物混合装置用低成本打印机的可打印树脂的细胞毒性和特性	Liao, A. S.	PDF	N/A	Cytotoxicity and Characterization of 3D-Printable Resins Using a Low-Cost Printer for Muscle-based Biohybrid Devices
利用水和其自由基进行碰撞诱导和氧附着解离的双重碎裂，实现C=C位点解析的脂质组学	Takeda, H.	PDF	N/A	Dual fragmentation via collision-induced and oxygen attachment dissociations using water and its radicals for C=C position-resolved lipidomics
一种快速、肌肉驱动的生物混合游泳机器人	Drennan, W. C.	PDF	N/A	A fast, muscle-actuated biohybrid swimming robot
神经肌肉骨骼建模流程：基于MATLAB的OpenSim模型个性化与治疗优化功能	Hammond, C. V.	PDF	N/A	The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim
基因表达的多重超声成像	Nystrom, N. N.	PDF	N/A	Multiplexed ultrasound imaging of gene expression
使用基于贝叶斯优化的迭代实验设计加速细胞培养基开发	Narayanan, H.	PDF	N/A	Accelerating Cell Culture Media Development Using Bayesian Optimization-Based Iterative Experimental Design
RCANE：一种利用RNA-seq数据进行全基因组泛癌种体细胞拷贝数变异预测的深度学习算法	Ge, C.	PDF	N/A	RCANE: A Deep Learning Algorithm for Whole-genome Pan-Cancer Somatic Copy Number Aberration Prediction using RNA-seq Data
DSA-DeepFM：一种用于预测抗癌协同药物组合的双阶段注意力增强DeepFM模型	Gu, Y.	PDF	N/A	DSA-DeepFM: A Dual-Stage Attention-Enhanced DeepFM Model for Predicting Anticancer Synergistic Drug Combinations
AnnSQL：一个基于Python SQL的包，用于在笔记本电脑上进行大规模单细胞基因组学分析	Pavan, K.	PDF	N/A	AnnSQL: A Python SQL-based package for large-scale single-cell genomics analysis on a laptop
Limelight - 一个开源的基于网络的工具，用于可视化、分享和分析来自DDA管道的质谱数据	Riffle, M.	PDF	N/A	Limelight - An open, web-based tool for visualizing, sharing, and analyzing mass spectrometry data from DDA pipelines
Squeakuences：一个便携工具，用于格式化干净无瑕的序列，以消除生物信息学软件的不兼容性	Forsythe, E. S. S.	PDF	N/A	Squeakuences: a portable tool for formatting squeaky-clean sequences to eliminate bioinformatic software incompatibilities
CytoSpatio：利用多范围、多类型点过程模型学习细胞类型的空间关系	Chen, H.	PDF	N/A	CytoSpatio: Learning cell type spatial relationships using multirange, multitype point process models
AlloPool：一种用于蛋白质系统中动态变构网络预测的自适应图神经网络	Barth, P.	PDF	N/A	AlloPool: An Adaptive Graph Neural Network for Dynamic Allosteric Network Prediction in Protein Systems
KOnezumi-AID：一种利用Target-AID自动化设计多重基因敲除的软件	Taki, T.	PDF	N/A	KOnezumi-AID: A Software to Automate the Design of Multiplex Knockouts Using Target-AID
SpaMTP：空间代谢组学和转录组学数据的整合统计分析与可视化。	Causer, A.	PDF	N/A	SpaMTP: Integrative Statistical Analysis and Visualisation of Spatial Metabolomics and Transcriptomics data.
使用残差神经网络对基因区域中可变剪接事件的差异分析	Ciccolella, S.	PDF	N/A	Differential Analysis of Alternative Splicing Events in gene regions using Residual Neural Networks
DiCARN-DNase: 利用扩张级联ResNet结合自注意力和DNase-seq染色质可及性数据提升细胞间Hi-C分辨率	Olowofila, S. A.	PDF	N/A	DiCARN-DNase: Enhancing Cell-to-Cell Hi-C Resolution Using Dilated Cascading ResNet with Self-Attention and DNase-seq Chromatin Accessibility Data
克服公共数据库中脊椎动物硒蛋白基因注释的普遍缺陷	Tico, M.	PDF	N/A	Overcoming the widespread flaws in the annotation of vertebrate selenoprotein genes in public databases
利用空间蛋白质组学和少样本学习对原发组织进行高精度预测，以推断5年无进展黑色素瘤生存率	Moeller, A.	PDF	N/A	High-accuracy prediction of 5-year progression-free melanoma survival using spatial proteomics and few-shot learning on primary tissue
使用TemSOMap将单细胞RNA测序的谱系解析数据与空间转录组学数据进行映射	Pan, X.	PDF	N/A	Mapping lineage-resolved scRNA-seq data with spatialtranscriptomics using TemSOMap
量化荧光标记蛋白的核定位	Hurbain, J.	PDF	N/A	Quantifying the nuclear localisation of fluorescently tagged proteins
scRNA-seq与网络传播的联合应用突显了泛癌肿瘤浸润T细胞的关键特征	MANGELINCK, A.	PDF	N/A	The combined use of scRNA-seq and network propagation highlights key features of pan-cancer Tumor-Infiltrating T cells
检测海洋共生体中的特殊基因：一种系统发育偏差方法识别出增强重组的变体	Zhou, X.	PDF	N/A	Detecting Special Genes in Marine Symbionts: A Phylogeny-Deviation Approach Identifies Recombination-Enhancing Variants
CIWARS：一种基于纵向宏基因组数据的水传播抗生素抗性监测网络服务器	Emon, M. I.	PDF	N/A	CIWARS: a web server for waterborne antibiotic resistance surveillance using longitudinal metagenomic data
BTS：可扩展的贝叶斯组织评分，用于在多组学数据中优先考虑GWAS变异及其功能背景	Kuksa, P. P.	PDF	N/A	BTS: scalable Bayesian Tissue Score for prioritizing GWAS variants and their functional contexts across omics data
AutoPM3：通过LLM驱动的PM3证据提取增强变体解读	Li, S.	PDF	N/A	AutoPM3: Enhancing Variant Interpretation via LLM-driven PM3 Evidence Extraction from Scientific Literature
PEI促进高效基因递送至细胞的分子参数解析	Montano Gonzalez, P. A.	PDF	N/A	Insight Into the Molecular Parameters of PEI Promoting an Efficient Gene Delivery into Cells
溶酶体阳离子通道TMEM175的选择性通透性与门控机制	Schulze, T.	PDF	N/A	Proton selective conductance and gating of lysosomal cation channel TMEM175
临床相关伯克霍尔德菌属产β-内酰胺酶的动态差异	Gu, J.	PDF	N/A	Dynamic Differences in Clinically relevant Pen β-Lactamases from Burkholderia spp.
探索恶性疟原虫二氢叶酸还原酶的适应性景观：抗叶酸耐药性的进化见解	Muzata, D.	PDF	N/A	Navigating the Fitness Landscapes of Plasmodium falciparum Dihydrofolate Reductase: Evolutionary Insights into Antifolate Resistance
异质性诱导的受限嵌段共聚物分相	Mohanta, D.	PDF	N/A	Heterogeneity induced Block Copolymer Segregation in Confinement
基于密度的无偏、可重复聚类优化应用于单分子定位显微镜	Hammer, J. L.	PDF	N/A	Density-based optimization for unbiased, reproducible clustering applied to single molecule localization microscopy
用于指导低温聚焦离子束铣削超越轴向衍射极限的光学干涉	Sica, A. V.	PDF	N/A	Optical Interference for the Guidance of Cryogenic Focused Ion Beam Milling Beyond the Axial Diffraction Limit
研究绿色方法合成铜纳米颗粒与电离辐射对乳酸脱氢酶（LDH）的影响	Sih, B. T.	PDF	N/A	Study the Effect of Green Method Synthesis of Copper Nanoparticles with Ionization Radiation on Lactate Dehydrogenase (LDH)
无模型光子分析扩散型单分子FRET实验	Terterov, I.	PDF	N/A	Model-free photon analysis of diffusion-based single-molecule FRET experiments
Kauffman模型中闭合与开放式进化之间因果关系的证据	Faggian, M. F.	PDF	N/A	Evidence of causality between Closure and Open-Ended Evolution in the Kauffman model
内在的生物能量适应性变化补偿了HER2驱动的乳腺肿瘤中线粒体含量的减少。	Frangos, S. M.	PDF	N/A	Intrinsic bioenergetic adaptations compensate for reduced mitochondrial content in HER2-driven mammary tumors
自噬与外泌体途径的相互调控通过GABARAPL2和Alix介导，以促进细胞稳态	soni, N.	PDF	N/A	Reciprocal regulation of autophagy and exosome pathway is mediated by GABARAPL2 and Alix to facilitate cellular homeostasis
雄激素受体相互作用揭示了内分泌抵抗性乳腺癌中类固醇介导的代谢转变。	Bleach, R.	PDF	N/A	Androgen receptor interactions provide insight into steroid mediated metabolic shifts in endocrine resistant breast cancer.
TET1通过表观遗传重塑和免疫调节在肺腺癌中发挥肿瘤抑制作用	Rahim, A.	PDF	N/A	TET1 Functions as a Tumor Suppressor in Lung Adenocarcinoma Through Epigenetic Remodeling and Immune Modulation
在胶质母细胞瘤中进行原位单细胞空间分析，评估基质基因表达	De, A.	PDF	N/A	In Situ Single-Cell Spatial Profiling of Matrisome Gene Expression in Glioblastoma
ADAT2/3介导的tRNA编辑促进癌细胞生长和肿瘤发生	Ramirez-Moya, J.	PDF	N/A	ADAT2/3-mediated tRNA editing promotes cancer cell growth and tumorigenicity
XPO1抑制通过调节Wnt/β-连环蛋白信号通路来减少结直肠癌的肿瘤发生。	Evans, A. E.	PDF	N/A	XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis.
胰腺神经内分泌肿瘤综合RNA剪接图谱揭示了新的临床分子关联	Blazquez-Encinas, R.	PDF	N/A	An integrative RNA spliceosomic landscape of pancreatic neuroendocrine tumors unveils novel clinicomolecular associations
可遗传的细胞状态塑造了癌细胞中的药物持久性相关性和种群动态	Iyer, A.	PDF	N/A	Inheritable cell-states shape drug-persister correlations and population dynamics in cancer cells
使用化学合成约束双环肽条件性激活NK细胞功能，针对NKp46和肿瘤表达的抗原	Dufort, F. J.	PDF	N/A	Conditional activation of NK cell function using chemically synthetic constrained bicyclic peptides directed against NKp46 and tumor-expressed antigens
利用公民科学方法进行以研究为导向的进化论和古生物学教学	Lautenschlager, S.	PDF	N/A	Using a citizen science approach for research-informed teaching of evolution and palaeontology
Nef在南非女性中复制能力强的HIV库长期维持中的作用	Ismail, S. D.	PDF	N/A	The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women
脂肪酸介导的HepaRG细胞中CYP2E1活性的诱导并不系统性地与对乙酰氨基酚的细胞毒性加剧相关。	Penhoat, C.	PDF	N/A	Fatty acid-mediated induction of CYP2E1 activity in HepaRG cells is not systematically associated with exacerbated acetaminophen cytotoxicity
黄嘌呤氧化还原酶的亚硝酸盐还原酶活性维持心血管健康	Dyson, N.	PDF	N/A	The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular health
来自患有肠病的孟加拉国发育迟缓儿童的小肠细菌的代际传递的影响	Pruss, K. M.	PDF	N/A	Effects of intergenerational transmission of small intestinal bacteria cultured from stunted Bangladeshi children with enteropathy
昆虫识别软件AInsectID版本1.1：基于深度卷积神经网络迁移学习的昆虫物种识别软件	Sadia, H.	PDF	N/A	AInsectID Version 1.1: an Insect Species Identification Software Based on the Transfer Learning of Deep Convolutional Neural Networks
言论自由在全球范围内预示着动物福利保护	Montalcini, C. M.	PDF	N/A	Freedom of speech predicts animal welfare protection across the globe
ImmunoStruct：整合蛋白质序列、结构和生化特性以进行免疫原性预测与解释	Givechian, K. B.	PDF	N/A	ImmunoStruct: Integration of protein sequence, structure, and biochemical properties for immunogenicity prediction and interpretation
未锚定的泛素链通过UBXN1促进非经典炎症小体	Yang, D.	PDF	N/A	Unanchored ubiquitin chains promote the non-canonical inflammasome via UBXN1
一种新颖的开源培养系统助力建立了首个涉及巨型纤毛虫Zoothamnium niveum的全周期化学合成共生模型系统。	Contarini, P.-E.	PDF	N/A	A novel open-source cultivation system helps establish the first full cycle chemosynthetic symbiosis model system involving the giant ciliate Zoothamnium niveum
材料性质与细胞效应之间的相互作用驱动了氧化石墨烯与癌细胞和非癌细胞之间不同的相互作用模式。	Chen, Y.	PDF	N/A	Interplay between material properties and cellular effects drives distinct pattern of interaction of graphene oxide with cancer and non-cancer cells
转录因子聚类的特异性在基因组中被编码	Dongre, S.	PDF	N/A	Specificity in transcription factor clustering is encoded in the genome
父母谈判策略演变中替代后代抚养模式的涌现	Zheng, J.	PDF	N/A	Emergence of alternative offspring care patterns from the evolution of parental negotiation strategies
松鼠：从四叶网络或序列比对中重建半有向的系统发育一级网络	Holtgrefe, N.	PDF	N/A	Squirrel: Reconstructing semi-directed phylogenetic level-1 networks from four-leaved networks or sequence alignments
城市和农村白三叶草种群中选择性清除的特征	Santangelo, J.	PDF	N/A	Signatures of selective sweeps in urban and rural white clover populations
双相适应性进化抗菌药物耐药性	Das, S. G.	PDF	N/A	Biphasic adaptive evolution of antimicrobial resistance
在溯祖分化模型中分支大小的分布	Song, Y.	PDF	N/A	The distribution of clade size in a coalescent diversification model
跨拓扑关联域（TAD）边界的旁观者激活支持了一种依赖于凝聚蛋白的增强子功能枢纽模型	Williamson, W. I.	PDF	N/A	Bystander activation across a TAD boundary supports a cohesin-dependent hub-model for enhancer function
体内单细胞核糖体分析揭示了衰老过程中细胞类型特异性翻译程序	Dure, C.	PDF	N/A	In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging
创伤应激暴露后，随着时间和组织的变化，转录水平的改变为我们提供了分子层面的见解，揭示了治疗机会窗口的存在。	McKibben, L. A.	PDF	N/A	Transcriptional changes across tissue and time provide molecular insights into a therapeutic window of opportunity following traumatic stress exposure
通过FUNCODE量化人类和小鼠调控元件的功能保守性	Fang, W.	PDF	N/A	Quantifying Functional Conservation of Human and Mouse Regulatory Elements via FUNCODE
来自受污染宿主的Kudoa基因组显示出广泛的基因组顺序保守性和快速的序列进化。	Weber, C. C.	PDF	N/A	Kudoa genomes from contaminated hosts reveal extensive gene order conservation and rapid sequence evolution
人类皮下脂肪组织的单细胞DNA甲基组和三维基因组图谱	Chen, Z. J.	PDF	N/A	Single-cell DNA methylome and 3D genome atlas of the human subcutaneous adipose tissue
高通量制备胶原微球用于三维细胞培养及胞外囊泡生产	Ali, S.	PDF	N/A	High-throughput Generation of Collagen Microbeads for 3D Cell Culture and Extracellular Vesicle Production
基于Transformer的生存结果预测方法	Mellors, T.	PDF	N/A	A Transformer-Based Approach to Survival Outcome Prediction
基于组织学的微卫星不稳定性与免疫治疗反应预测的深度高斯过程及不确定性估计	Park, S.	PDF	N/A	Deep Gaussian Process with Uncertainty Estimation for Microsatellite Instability and Immunotherapy Response Prediction Based on Histology
评估从单细胞RNA测序数据中构建T细胞受体的方法	Tian, R.	PDF	N/A	Evaluation of T Cell Receptor Construction Methods from scRNA-Seq Data
GenoSiS：一种用于创建动态患者匹配队列的生物库规模基因型相似性搜索架构	Schneider, K.	PDF	N/A	GenoSiS: A Biobank-Scale Genotype Similarity Search Architecture for Creating Dynamic Patient-Match Cohorts
揭开睡眠之谜：探索新近描述的洛基城堡附近洛基古菌门中的系统发生基因组睡眠信号	Pandi-Perumal, S. R.	PDF	N/A	Unraveling the Mysteries of Sleep: Exploring Phylogenomic Sleep Signals in the Recently Characterized Archaeal Phylum Lokiarchaeota near Loki's Castle
利用主题建模探索转录组数据的潜在空间	Valle, F.	PDF	N/A	Exploring the latent space of transcriptomic data withtopic modeling
疾病相关突变会扰乱神经凝聚物的物理性质、组成和RNA翻译。	Ahangama Liyanage, L.	PDF	N/A	Disease-linked mutations dysregulate neuronal condensate physical properties, composition, and RNA translation
修订的扩散定律允许对膜组织的纳米尺度进行定量表征	Svobodova, B.	PDF	N/A	Revised diffusion law permits quantitative nanoscale characterization of membrane organization
GPCR-G蛋白预偶联与激活的结构基础：从CCR1-Gi复合物中获得的见解	Shao, Z.	PDF	N/A	Structural Basis of GPCR-G Protein Pre-coupling and Activation: Insights from CCR1-Gi Complex
局部离子条件调节α-突触核蛋白的聚集倾向，并影响其结构多态性。	Zacharopoulou, M.	PDF	N/A	Local ionic conditions modulate the aggregation propensity and influence the structural polymorphism of alpha-synuclein
一种新的99mTc-PSMA-HBED-CC标记方法	Phromphao, B.	PDF	N/A	A New Labelling Method of 99mTc-PSMA-HBED-CC
β-羟基丁酸代谢的另一途径支持癌细胞中的脂肪酸合成	Kaluba, F. C.	PDF	N/A	An alternative route for β-hydroxybutyrate metabolism supports fatty acid synthesis in cancer cells
每个癌症细胞的转录组中都编码了患者肿瘤中一种独特的恶性细胞类型。	Saurty-Seerunghen, M. S.	PDF	N/A	A unique malignant cell type per patient tumor is encoded in each cancer cell transcriptome.
白血病对健康的造血干细胞和祖细胞具有持久的印记。	Chen, D.-W.	PDF	N/A	Leukemia confers a durable imprint on healthy hematopoietic stem and progenitor cells
利用斑鸠菊叶提取物进行生物银纳米颗粒的植物辅助合成：表征、抗菌、抗炎及急性毒性概况	Nyuyfoni, G. F.	PDF	N/A	Phytoassisted synthesis of biogenic silver nanoparticles using Vernonia amygdalina leaf extract: characterization, antibacterial, anti-inflammatory, and acute toxicity profile
ABRpresto：一种利用子平均间的重采样互相关进行听觉脑干反应自动阈值设定的算法	Shaheen, L. A.	PDF	N/A	ABRpresto: An algorithm for automatic thresholding of the Auditory Brainstem Response using resampled cross-correlation across subaverages
PGR5对于叶绿体和蓝细菌中依赖氧化还原的ATP合酶调控是必需的。	Nikkanen, L.	PDF	N/A	PGR5 is needed for redox-dependent regulation of ATP synthase both in chloroplasts and in cyanobacteria
结构变异有助于水稻的遗传多样性和杂种优势	Dan, Z.	PDF	N/A	Structural variations contribute to genetic diversity and heterosis in rice
线粒体效率决定酵母中的克鲁勃效应	Battjes, J.	PDF	N/A	Mitochondrial efficiency determines Crabtree effect across yeasts
突触和体细胞靶向的ArcLight，一种遗传编码的电压指示器	Zhong, S.	PDF	N/A	Synaptic and Somatic Targeting of ArcLight, a Genetically Encoded Voltage Indicator
非免疫人血清中的C1q对临床结核分枝杆菌复合体菌株具有非冗余的补体功能。	Duque, M. A.	PDF	N/A	C1q in non-immune human serum has a non-redundant complement function towards clinical Mycobacterium tuberculosis complex strains
成骨细胞和骨肉瘤中大规模染色体构象的差异调控	Bisht, M.	PDF	N/A	Differential Regulation of Large-scale Chromosome Conformations in Osteoblasts and Osteosarcoma
AURKA通过磷酸化HEC1来控制卵母细胞纺锤体组装检验点和染色体对齐。	Blengini, C. S.	PDF	N/A	AURKA controls oocyte spindle assembly checkpoint and chromosome alignment by HEC1 phosphorylation
SUV39H1介导的KLF4和KDM4A调控协同调节平滑肌细胞表型可塑性	Chatterjee, P.	PDF	N/A	SUV39H1 mediated regulation of KLF4 and KDM4A coordinate smooth muscle cell phenotypic plasticity
来自软骨中间带的CILP通过Keap1-Nrf2轴抑制早期骨关节炎运动疗法中的透明软骨纤维化和软骨细胞铁死亡	Jia, S.	PDF	N/A	CILP from Cartilage Intermediate Zone Inhibits Hyaline Cartilage Fibrosis and Chondrocyte Ferroptosis via Keap1-Nrf2 Axis in Early Osteoarthritis Exercise Therapy
使用染色质纤维分析和R-ODD-BLOBS程序建模DNA复制叉的稳定性和崩溃	Cheng, K.	PDF	N/A	Modelling DNA replication fork stability and collapse using chromatin fiber analysis and the R-ODD-BLOBS program
与选择性伐木和森林再生相关的系统发育和功能组成变化在刚果盆地的热带雨林中	Depecker, J.	PDF	N/A	Phylogenetic and functional compositional shifts associated with selective logging and forest regrowth in tropical rainforests of the Congo Basin
岛屿人口统计学：哥特兰岛标志性金雕的繁殖动态及驱动因素	Singh, N. J.	PDF	N/A	Island population demography: Breeding dynamics and drivers of Gotland's iconic Golden Eagles
利用代谢生物标志物绘制病毒分流在广泛分布的颗石藻藻华中的分布图	Kuhlisch, C.	PDF	N/A	Mapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers
环境DNA和野生动物相机陷阱揭示了淡水花岗岩岩池中互补的脊椎动物访问模式	Hedges, B. A.	PDF	N/A	Environmental DNA and wildlife camera traps uncover complimentary vertebrate visitation patterns at freshwater granite rock-holes
合成基因驱动在种群抑制中的自然选择可以倾向于驱动的中等强度。	Beaghton, P. J.	PDF	N/A	Natural selection of synthetic gene drives for population suppression can favour an intermediate strength of drive
周期基因改变了亚洲玉米螟的昼夜和季节性时间调控	Dayton, J. N.	PDF	N/A	The period gene alters daily and seasonal timing in Ostrinia nubilalis
社会家庭结构和生物地理学促进了唯一一种真社会性甲虫——Austroplatypus incompertus（象甲科：Platypodinae亚科）的基因组分化和隐秘物种形成。	Bickerstaff, J.	PDF	N/A	Social family structure and biogeography contribute to genomic divergence and cryptic speciation in the only eusocial beetle species, Austroplatypus incompertus (Curculionidae: Platypodinae)
atad3-null斑马鱼胚胎的转录组分析揭示了可能的疾病机制	Ezer, S.	PDF	N/A	Transcriptome analysis of atad3-null zebrafish embryos elucidates possible disease mechanisms
多基因评分-罕见变异因果枢轴：复杂疾病遗传学发现的条件性方法	Shaw, C. A.	PDF	N/A	The Polygenic Score - Rare Variant Causal Pivot: A Conditional Approach to Discovery in Complex Disease Genetics
一个用于CADD评分生成的通用流程：鸡CADD和火鸡CADD	Lensing, K.	PDF	N/A	A generic pipeline for CADD score generation: chickenCADD and turkeyCADD
探索基于微孔的单细胞RNA测序方法（HIVE），用于简化马支气管肺泡灌洗细胞的处理	Fegraeus, K.	PDF	N/A	Exploring a pico-well based scRNA-seq method (HIVE) for simplified processing of equine bronchoalveolar lavage cells
一种全基因组编码，用于定义细胞类型特异的CTCF结合和染色质组织	Do, C.	PDF	N/A	A genome wide code to define cell-type specific CTCF binding and chromatin organization
无标记鸟枪法蛋白质组学中监测宿主细胞蛋白质的MS/MS搜索算法比较分析，使用捕获离子迁移和ddaPASEF技术	Plisnier, M.	PDF	N/A	Comparative analysis of MS/MS search algorithms in label-free shotgun proteomics for monitoring host-cell proteins using trapped ion mobility and ddaPASEF
修饰肽、可编程的DNA四面体用于调节生物系统中的自噬	Naveena, H. A.	PDF	N/A	Peptide modified, programmable DNA tetrahedra to modulate autophagy in biological systems
利用声学报告基因进行基于细胞的非侵入性成像	Shivaei, S.	PDF	N/A	Non-invasive imaging of cell-based therapies using acoustic reporter genes
qByte：开源等温荧光计，旨在普及核酸、蛋白质和细胞的分析	Lombardero, F. J. Q.	PDF	N/A	qByte: Open-source isothermal fluorimeter for democratizing analysis of nucleic acids, proteins and cells
长期大变形过程中三维多细胞动力学引起的应变软化和滞后现象	Tsubota, K.-i.	PDF	N/A	Strain softening and hysteresis arising from 3D multicellular dynamics during long-term large deformation
脉冲场消融过程中热侧效应的定量分析	Mercado Montoya, M.	PDF	N/A	Quantification of thermal side effects during pulsed field ablation
利用语言引导的视觉模型进行空间蛋白质组学的广义细胞表型分析	Wang, X.	PDF	N/A	Generalized cell phenotyping for spatial proteomics with language-informed vision models
数据驱动的基因表达特征富集分析优化	Wenzel, A. T.	PDF	N/A	Data driven refinement of gene expression signatures for enrichment analysis
通过Visium、GeoMx DSP和Chromium方法对存档肿瘤组织进行转录组分析，揭示了患者间和患者内的异质性	Dong, Y.	PDF	N/A	Transcriptome Analysis of Archived Tumor Tissues by Visium, GeoMx DSP, and Chromium Methods Reveals Inter- and Intra-Patient Heterogeneity
通过种子线性规划与逆折叠和蛋白质语言模型进行抗体库设计	Hayes, C. F.	PDF	N/A	Antibody Library Design by Seeding LinearProgramming with Inverse Folding and ProteinLanguage Models
使用深度学习方法进行蛋白质复合物物理感知模型精度估计	Wang, H.	PDF	N/A	Physical-aware model accuracy estimation for protein complex using deep learning method
Smile-to-Bert：一种为物理化学性质预测和SMILES嵌入生成而训练的BERT架构	Barranco-Altirriba, M.	PDF	N/A	Smile-to-Bert: A BERT architecture trained for physicochemical properties prediction and SMILES embeddings generation
利用预训练视觉变换器和大型语言模型进行癫痫发作预测	Parani, P.	PDF	N/A	Utilizing Pretrained Vision Transformers and LargeLanguage Models for Epileptic Seizure Prediction
基于单基因的AI模型通过整合全基因组CRISPR和组学数据的生物学解释，识别核心及特定环境下的必需基因	Chou, C.-Y.	PDF	N/A	A single-gene-based AI model to identify core and context-specific essential genes by biological interpretation from pooled genome-wide CRISPR and omics data
DGRNA：一种具有双向注意力机制的长上下文RNA基础模型 Mamba2	Yuan, Y.	PDF	N/A	DGRNA: a long-context RNA foundation model with bidirectional attention Mamba2
在非结构化环境中导航：评估AlphaFold在预测蛋白质中缺失残基和结构无序方面的有效性	Zheng, S.	PDF	N/A	Navigating the Unstructured by Evaluating AlphaFold's Efficacy in Predicting Missing Residues and Structural Disorder in Proteins
FIBOS：用于分析蛋白质包装和结构的R和Python包	Soares, H. H. M.	PDF	N/A	FIBOS: R and Python packages for analyzing protein packing and structure
细菌种群聚集模型中非指数反转时间的角色	Batista, M.	PDF	N/A	Role of Non-Exponential Reversal times in Aggregation Models of Bacterial Populations
评估阿尔茨海默病中淀粉样β和Tau寡聚体的联合神经毒性：一项新标准	Kuznetsov, A. V.	PDF	N/A	Evaluating Combined Neurotoxicity of Amyloid Beta and Tau Oligomers in Alzheimer's Disease: A New Criterion
上采样点扩散函数（PSF）实现了高精度的三维超分辨率成像，同时保持了稀疏的采样率。	Chen, J.	PDF	N/A	Up sampled PSF enables high accuracy 3D super-resolution imaging with sparse sampling rate
抑制H3K27M增强的ATM信号通路可提高弥漫中线胶质瘤的放疗效果	Peterson, E. R.	PDF	N/A	Inhibition of H3K27M-enhanced ATM signaling increases radiation efficacy in diffuse midline glioma
HIRA-SETDB1-H3K9me3轴调控慢性髓系白血病细胞的染色质结构	Shirude, M. B.	PDF	N/A	HIRA-SETDB1-H3K9me3 axis regulate chromatin architecture in chronic myeloid leukemia cells
IKAROS促进B细胞急性淋巴母细胞白血病在面对CD19和CD22靶向治疗时的抗原逃逸。	Domizi, P.	PDF	N/A	IKAROS facilitates antigen escape in the face of CD19- and CD22-targeted therapies for B-cell acute lymphoblastic leukemia
CT诊断颞下颌关节骨关节炎的准确性相对于组织病理学发现——一项针对41匹马的离体研究	Jasinski, T.	PDF	N/A	Accuracy of computed tomography in diagnosing temporomandibular joint osteoarthritis relative to histopathological findings - an ex-vivo study of 41 horses
针对CD38阳性血液系统恶性肿瘤的靶向阿尔法疗法：Ac-巨噬细胞-伊沙妥昔单抗	Herrero Alvarez, N.	PDF	N/A	Targeted Alpha Therapy with Ac-Macropa-Isatuximab for CD38-positive Hematological Malignancies
缺氧暴露微调海龟细胞的线粒体功能	Arango, B. G.	PDF	N/A	Hypoxia exposure fine-tunes mitochondrial function in sea turtle cells
着丝粒重复多样性导致啤酒花（Humulus lupulus）中非孟德尔分离模式	Horakova, L.	PDF	N/A	Centromeric repeat diversity underlies non-Mendelian segregation pattern in hop (Humulus lupulus)
通过信号输入和细胞间通讯调节胰腺β细胞的钙动力学	Shang, X.	PDF	N/A	Tunability of calcium dynamics by signaling inputs and cell-cell communication in pancreatic beta cells
跨多个数据集的复杂动作停止探索：对动作取消和重新编程机制的洞察	Salomoni, S. E.	PDF	N/A	An exploration of complex action stopping across multiple datasets: Insights into the mechanisms of action cancellation and re-programming
表达速激肽1的丘脑下核旁亚核神经元控制主动回避学习	Hu, R.	PDF	N/A	Tachykinin1-expressing neurons in the parasubthalamic nucleus control active avoidance learning
放射性核素疗法的低剂量辐射增强了GD2 TRAC-CAR T细胞在局部神经母细胞瘤中的疗效	Sodji, Q. H.	PDF	N/A	Low Dose Radiation by Radiopharmaceutical Therapy Enhances GD2 TRAC-CAR T Cells Efficacy in Localized Neuroblastoma
两亲分子工程化的DNA佐剂通过细胞质危险感应刺激淋巴结中强烈的I型干扰素产生，从而在小鼠和非人灵长类动物中诱导强大的细胞和体液免疫。	Steinbuck, M. P.	PDF	N/A	Amphiphile-engineered DNA adjuvants stimulate strong type I IFN production in lymph nodes via cytosolic danger-sensing to induce potent cellular and humoral immunity in mice and non-human primates
对Fc效应功能的要求可以通过广谱反应性抗α病毒抗体的结合效力来克服。	Callahan, V.	PDF	N/A	Requirement for Fc effector function is overcome by binding potency for broadly reactive anti-alphavirus antibodies
时空限制的Hippo信号传导指导肝胆细胞的命运和成熟	Wang, Y.	PDF	N/A	Spatiotemporally restricted Hippo signalings instruct the fate and maturation of hepatobiliary cells
利用成像光谱学在混合温带森林中绘制冠层叶片功能性状图	Gravel, A.	PDF	N/A	Mapping canopy foliar functional traits in a mixed temperate forest using imaging spectroscopy
NANUQ+：一种用于网络估计的分治方法	Allman, E. S.	PDF	N/A	NANUQ+: A divide-and-conquer approach to network estimation
混合长度基因组测序（blend-seq）：结合短读长与低覆盖度长读长以最大化变异发现	Magner, R.	PDF	N/A	Blended Length Genome Sequencing (blend-seq): Combining Short Reads with Low-Coverage Long Reads to Maximize Variant Discovery
跨界基因组中人类睡眠相关基因直系同源基因的保守性：来自莱茵衣藻的系统基因组学证据	Pandi-Perumal, S. R.	PDF	N/A	Cross-Kingdom Genomic Conservation of Human Sleep-Related Gene Orthologs: Phylogenomic Evidence from Chlamydomonas reinhardtii
较长的内含子往往含有更多的串联重复序列，并且经历插入和删除的频率更高。	Homma, K.	PDF	N/A	Longer Internal Exons Tend to Have More Tandem Repeats and Experience Insertions and Deletions More Frequently
# BioRxiv 2024-11-02 Papers

标题	作者	PDF链接	代码仓库	Title
阳光强度对水稻（Oryza sativa ssp. indica）地方品种开花时间和暴露持续时间的影响	Deb, D.	PDF	N/A	The Effect of Sunlight Intensity on Flower Opening Time and Exposure Duration in Rice (Oryza sativa ssp. indica) Landraces
一个整合了机制的模型，描述了在单一资源上进行的开发性和干扰性竞争，产生了广泛的共存现象。	Smith, D. J. B.	PDF	N/A	A Mechanistically Integrated Model of Exploitative and Interference Competition over a Single Resource Produces Widespread Coexistence
精神分裂症相关DRD2基因突变的影响及其与断奶后孤立小鼠模型中社会行为与生化变化的关联	Mukesh, N.	PDF	N/A	Effect of Schizophrenia linked DRD2 gene mutations and correlation of social behavior with biochemical changes in a post-weaning isolated mouse model
敲除细胞周期依赖性激酶8和19会导致细胞周期蛋白C的耗竭，并抑制小鼠的精子发生和雄性生育能力。	Bruter, A. V.	PDF	N/A	Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice
不同物种和发育阶段的海马和新皮层中阿片类药物介导的抑制性抑制的差异	Caccavano, A. P.	PDF	N/A	Divergent opioid-mediated suppression of inhibition between hippocampus and neocortex across species and development
通过双功能HSV载体治疗性疫苗清除慢性SIV感染猕猴体内的病毒潜伏期	Wen, Z.	PDF	N/A	Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
使用生成模型预测蛋白质折叠的绝对稳定性	Cagiada, M.	PDF	N/A	Predicting absolute protein folding stability using generative models
互补的遗传和表观遗传变化有助于快速适应多种全球变化压力	Brennan, R.	PDF	N/A	Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors
放射科医生感知错误的神经认知机制：初步研究结果	Bruno, M. A.	PDF	N/A	Neurocognitive Mechanism of Radiologists Perceptual Errors: Results of Preliminary Studies
Dnajc12敲除小鼠的特征分析，作为低多巴胺能的模型	Deng, I. B.	PDF	N/A	Characterization of Dnajc12 knockout mice, a model of hypodopaminergia
一种经济实惠的解决方案，用于研究斑胸草雀颅内脑电图（iEEG）信号	Abolghasemi, M.-M.	PDF	N/A	An affordable solution for investigating zebra finch intracranial electroencephalography (iEEG) signals
利用DNA折纸纳米块对果蝇E-钙粘蛋白外域片段及其相互作用的纳米尺度可视化研究	Oda, H.	PDF	N/A	Nanoscale visualization of Drosophila E-cadherin ectodomain fragments and their interactions using DNA origami nanoblocks
身体自主感神经相关性	Regev Krugwasser, A.	PDF	N/A	Neural Correlates of the Embodied Sense of Agency
m6A RNA修饰在转录后水平上调控突触功能，这一过程在衰老以及突触核蛋白病的小鼠模型中发挥作用。	Chopra, A.	PDF	N/A	The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy
视神经头处的轴突运输受损在新型Cre诱导的小鼠青光眼模型中促进了神经退行性变	Kaipa, B. R.	PDF	N/A	Impaired axonal transport at the optic nerve head contributes to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucoma
p24家族成员TMED9通过快速内质网应激诱导的出口途径，协调错误折叠的GPI锚定蛋白从内质网到高尔基体的清除。	Ronzier, E.	PDF	N/A	The p24-family member, TMED9, coordinates clearance of misfolded GPI-anchored proteins from the ER to the Golgi via the Rapid ER Stress-Induced Export pathway
视觉特征注意力控制的分层组织	Meyyappan, S.	PDF	N/A	Hierarchical Organization of Visual Feature Attention Control
阻止BMP4前域磷酸化的突变会损害同源二聚体的蛋白水解成熟，导致小鼠早期死亡。	Kim, H.-s.	PDF	N/A	Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to early lethality in mice
一种针对鲍曼不动杆菌的新型烈性噬菌体：在小鼠肺部感染模型中的疗效和安全性	Wang, J.	PDF	N/A	A Novel Genus of Virulent Phage Targeting Acinetobacter baumannii: Efficacy and Safety in a Murine Model of Pulmonary Infection
表观基因组的趋同进化在生命之树中招募了DNA修复	Monroe, G.	PDF	N/A	Convergent evolution of epigenome recruited DNA repair across the Tree of Life
人类抗体识别的流感H1和H3血凝素上的保守位点	Maurer, D. P.	PDF	N/A	Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies
从光栅响应构建的编码流形在皮层视觉区域中组织了对自然场景的响应	Dyballa, L.	PDF	N/A	Encoding manifolds constructed from grating responses organize responses to natural scenes in cortical visual areas
后顶叶皮层介导了由稀有性引发的决策偏差以及在不确定性下的学习过程。	Sheng, W.	PDF	N/A	Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty
C9orf72扩展导致不稳定的叶酸敏感脆弱位点FRA9A的形成。	Mirceta, M.	PDF	N/A	C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A
类噬菌体CRISPR样调控RNA沉默细菌的适应性和先天免疫	Liu, C.	PDF	N/A	Phage CRISPR-like regulatory RNAs silence bacterial adaptive and innate immunity
简化胎鼠影像中的不对称量化：基于专家指导的半自动化流程	Rolfe, S. M.	PDF	N/A	Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance
Q_ST--F_ST比较中的错误率取决于遗传结构和估计程序	Liu, J. J.	PDF	N/A	Error rates in Q_ST--F_ST comparisons depend on genetic architecture and estimation procedures
通过全基因组比较谱系地理学揭示的新热带山地与低地鸟类显著的种内多样化动态差异	Wacker, K. S.	PDF	N/A	Distinct intraspecific diversification dynamics in Neotropical montane versus lowland birds revealed by whole-genome comparative phylogeography
基因组学和抗性检测有助于管理两种遭受入侵性桃金娘锈病病原体严重破坏的树种	Chen, S. H.	PDF	N/A	Genomics and resistance assays inform the management of two tree species being devastated by the invasive myrtle rust pathogen
在严重肺炎链球菌肺炎的小鼠模型中，中性粒细胞转录组分化为两条截然不同的轨迹	Pihl, R. M. F.	PDF	N/A	Neutrophil transcriptome diverges into two discrete trajectories in a murine model of severe Streptococcus pneumoniae pneumonia
Lowe综合征中神经发生缺陷是由线粒体丢失和与纤毛相关的音猬因子缺陷引起的。	Lo, C.	PDF	N/A	Defective Neurogenesis in Lowe Syndrome is Caused by Mitochondria Loss and Cilia-related Sonic Hedgehog Defects
补偿性进化以应对DNA复制压力对营养物质的可用性具有鲁棒性	Natalino, M.	PDF	N/A	Compensatory Evolution to DNA Replication Stress is Robust to Nutrient Availability
GDF5的复杂调控相互作用塑造了关节形态和骨关节炎疾病风险	Coveney, C. R.	PDF	N/A	Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk
人乙型肝炎病毒向新热带野生灵长类动物的跨物种传播	boubli, J.	PDF	N/A	Cross-species transmission of human hepatitis B virus to wild Neotropical primates
高通量、多重定量及单分子水平上的单个外泌体分选	Park, J.	PDF	N/A	High-throughput, multiplexed quantification, and sorting of single EVs at single-molecule level
用于单细胞数据整合的图正则化最优传输	Wang, Z.	PDF	N/A	Graph-Regularized Optimal Transport for Single-Cell Data Integration
使用可交换的寡核苷酸标签实现高吞吐量的单分子显微镜，具有可调节的空间分辨率	de Zwaan, K.	PDF	N/A	High-throughput single molecule microscopy with adaptable spatial resolution using exchangeable oligonucleotide labels
左星状神经节与右星状神经节神经元的电生理比较	Verkerk, A. O.	PDF	N/A	Electrophysiological comparison of left versus right stellate ganglia neurons
单细胞、空间和命运图谱分析揭示了耳蜗髓系细胞的微环境依赖性多样性。	Chiot, A.	PDF	N/A	Single-cell, spatial, and fate-mapping analyses uncover niche dependent diversity of cochlear myeloid cells.
夏威夷短尾鱿鱼早期阶段对海洋变暖和酸化的发育及转录组反应	Otjacques, E.	PDF	N/A	Developmental and transcriptomic responses of Hawaiian bobtail squid early stages to ocean warming and acidification
通过动力学限制的溶液相索引技术，实现了快速、简便且无需仪器的单细胞转录组分析	Marafini, P.	PDF	N/A	Solution-phase indexing by kinetic confinement enables rapid, simple, and instrument-free single cell transcriptional profiling
癌症基金会：一种单细胞RNA测序基础模型，用于解析癌症中的药物抗性	Theus, A.	PDF	N/A	CancerFoundation: A single-cell RNA sequencing foundation model to decipher drug resistance in cancer
MAPK信号通路调控植物细胞中DCP1在P-体与应激颗粒间的分配	He, S.-L.	PDF	N/A	MAPK signaling modulates the partition of DCP1 between P-bodies and stress granules in plant cells
植物内化学防御的变异并不能解释小菜蛾对Erysimum cheiranthoides的取食偏好。	Zuest, T.	PDF	N/A	Within-plant variation in chemical defence of Erysimum cheiranthoides does not explain Plutella xylostella feeding preference
稀有物种对高山植物群落系统发育多样性的贡献并不不成比例	Veldhuisen, L. N.	PDF	N/A	Rare species do not disproportionately contribute to phylogenetic diversity in a subalpine plant community
四个ZIP基因在根的外部区域参与了锌、铁、铜和锰的吸收过程。	ROBE, K.	PDF	N/A	Four ZIPs contribute to Zn, Fe, Cu and Mn acquisition at the outer root domain
一种超保守的ARF-DNA界面是生长素触发的转录反应的基础	Rienstra, J.	PDF	N/A	An ultra-conserved ARF-DNA interface underlies auxin-triggered transcriptional response
确保科学研究的稳健性：以分根实验为例	Salvatore, L.	PDF	N/A	Ensuring Robustness in Scientific Research, Split-root assays as an example case
早期分支蓝藻Anthocerotibacter panamensis中光系统I的结构与演化	Jiang, H.-W.	PDF	N/A	Structure and evolution of Photosystem I in the early-branching cyanobacterium Anthocerotibacter panamensis
SOQ1 在拟南芥叶绿体液泡中作为甲硫氨酸亚砜还原酶，用于调节光保护性 qH。	Hao, J.	PDF	N/A	SOQ1 functions as a methionine sulfoxide reductase in the chloroplast lumen for regulation of photoprotective qH in Arabidopsis
复杂鞘脂类在藓类植物小立碗藓的细胞分裂和质膜孔形成中起着至关重要的作用。	Wegner, L.	PDF	N/A	Complex sphingolipids are essential for cell division and plasmodesmal development in the moss Physcomitrium patens
大豆种子产量、蛋白质和油脂的基因组和表型预测	Van der Laan, L.	PDF	N/A	Genomic and Phenomic Prediction for Soybean Seed Yield, Protein, and Oil
特定物种叶际对外部pH变化的响应	Lopez Gonzalez, C.	PDF	N/A	Species-specific phyllosphere responses to external pH change
动物RNA病毒的基因组大小反映了系统发育的限制	Takada, K.	PDF	N/A	Genome sizes of animal RNA viruses reflect phylogenetic constraints
通过导管感染H5N1亚型2.3.4.4b流感病毒	Roubidoux, E. K.	PDF	N/A	Intraductal infection with H5N1 clade 2.3.4.4b influenza virus
来自印度恒河原始河段的新型Tequatrovirus噬菌体在减少污水细菌负荷中的特性研究	Samson, R.	PDF	N/A	Characterization of a Novel Tequatrovirus Phage from Pristine Stretch of The Ganges River, India, in Reducing Bacterial Load from Sewage Water
抑制鞭毛钩中赖氨酰丙氨酸交联的物质作为抗螺旋体微生物	Lynch, M. J.	PDF	N/A	Inhibitors of lysinoalanine crosslinking in the flagella hook as antimicrobials against spirochetes
微生物裂解物作为细胞农业培养基配方中的低成本血清代用品	Dolgin, J.	PDF	N/A	Microbial lysates as low-cost serum replacements in cellular agriculture media formulation
AnnotIEM：基于16S基因微生物测序的微生物组物种水平注释新工具	Bhatttacharyya, M.	PDF	N/A	AnnotIEM: novel tool for microbiome species-level annotation of 16S gene based microbial sequencing
乳腺肿瘤微生物群调节抗肿瘤免疫和T细胞相关代谢物	Liu, C.-C.	PDF	N/A	Breast tumor microbiome regulates anti-tumor immunity and T cell-associated metabolites
水稻植株中干旱诱导的活性氧调节与对黄单胞菌感染的抗性之间的相声	Ramu, D. S.	PDF	N/A	Crosstalk Between Drought-Induced ROS Regulation and Resistance to Xanthomonas oryzae Infection in Rice Plants
独脚金内酯参与促进玉米对铁的吸收	Fili, S.	PDF	N/A	Strigolactones are involved in enhancing iron uptake in maize
通过多模态方法表征高粱和亚麻荠对环境胁迫的响应	Seitz, K. A.	PDF	N/A	Characterizing the Responses of sorghum and Camelina to Environmental Stress through a Multi-Modal Approach
通过Ca2+传感器调控TIR信号传导，激活ADR1对pRib-AMP-EDS1-PAD4的识别，从而启动气孔免疫机制。	Wang, H.	PDF	N/A	Switch of TIR signaling by a Ca2+ sensor activates ADR1 recognition of pRib-AMP-EDS1-PAD4 for stomatal immunity
利用多环境试验育种数据优化基因型特异性参数评估木薯作物生长模型	Okoma, P. M.	PDF	N/A	Evaluating a Cassava Crop Growth Model by Optimizing Genotypic-Specific Parameters Using Multi-environment Trial Breeding Data
调控玉米杂交种中异交相关基因表达互补的机制	Pitz, M.	PDF	N/A	Regulation of heterosis-associated gene expression complementation in maize hybrids
广泛分布的野生植物在陡峭气候梯度下配子体性状对热胁迫的适应与驯化	Tushabe, D.	PDF	N/A	Adaptation and acclimation of gametophytic traits to heat stress in a widely distributed wild plant along a steep climatic gradient
光温巧合检测器的遗传结构	Seluzicki, A.	PDF	N/A	Genetic architecture of a light-temperature coincidence detector
数学模型指导最佳杀菌剂使用，以防治大豆菌核茎腐病，从而最大化大豆生产利润。	Byer, T.	PDF	N/A	A mathematical model informs optimal fungicide use against Sclerotinia stem rot to maximize profits in soybean production
豆科（蝶形花亚科）植物中一些重要特征的可能多重起源	Aygoren Uluer, D.	PDF	N/A	POSSIBLE MULTIPLE ORIGINS OF SOME IMPORTANT CHARACTERISTICS OF THE KEEL (PAPILIONATE) FLOWERS WITHIN FABALES
拟南芥SUFB和CLP蛋白酶调控SUFBC2D以操控叶绿体中铁硫簇的生物合成	Cheng, Y.	PDF	N/A	Arabidopsis SUFB and CLP protease regulate SUFBC2D to manipulate iron-sulfur cluster biosynthesis in chloroplast
LysR型转录因子PacR在调控Anabaena sp. PCC7120氮代谢中的作用	Werner, E.	PDF	N/A	The role of the LysR-type transcription factor PacR in regulating nitrogen metabolism in Anabaena sp. PCC7120
异戊二烯通过启动植物激素反应来驱避食草昆虫。	Sahu, A.	PDF	N/A	Isoprene deters insect herbivory by priming plant hormone responses
通过一个结构化的跨专业培训项目，提升护理人员管理1型糖尿病患儿的能力	Juhi, A.	PDF	N/A	Building capacity among caregivers for managing children with Type 1 Diabetes Mellitus through a structured Interprofessional training program
基于网络的表征学习揭示了时间和饮食对婴儿肠道微生物和代谢环境的影响	Price, A.	PDF	N/A	Network-based representation learning reveals the impact of time and diet on the gut microbial and metabolomic environment of infants
锌能增强一种反翻译抑制剂的效力，这种抑制剂能杀死结核分枝杆菌和非结核分枝杆菌。	Varshney, A.	PDF	N/A	A trans-translation inhibitor is potentiated by zinc and kills Mycobacterium tuberculosis and non-tuberculous mycobacteria
一种需要用于粘细菌胆固醇生产的香叶基香叶基还原酶同源物	Lee, A. K.	PDF	N/A	A geranylgeranyl reductase homolog required for cholesterol production in Myxococcota
胶原蛋白结合粘附素限制金黄色葡萄球菌皮肤感染	Bhattacharya, M.	PDF	N/A	Collagen binding adhesin restricts Staphylococcus aureus skin infection
在阿根廷恩特雷里奥斯省瓜莱瓜伊丘市患有阴道念珠菌病的育龄女性患者中分离出的念珠菌种	Perez Duarte, I. R.	PDF	N/A	Candida species isolated in female patients of reproductive age with vaginal candidiasis in Gualeguaychu, Entre Rios, Argentina
使用BONCAT解析金黄色葡萄球菌持久性菌株的蛋白质组	George Matlalcuatzi, E. D. C.	PDF	N/A	Using BONCAT To Dissect The Proteome Of S. aureus Persisters
特定连接泛素化靶向破坏揭示了K29连接泛素化在表观基因组完整性中的关键作用	Arroyo-Gomez, J.	PDF	N/A	Targeted disruption of linkage-specific ubiquitylation reveals a key role of K29-linked ubiquitylation in epigenome integrity
利用固定在无人驾驶飞行器上的轻便便携式空气采样器检测加州中央谷地空气中的球孢子菌孢子	Radosevich, M. T.	PDF	N/A	Detection of airborne Coccidioides spores using lightweight portable air samplers affixed to uncrewed aircraft systems in California's Central Valley
PAL-AI揭示了在卵母细胞成熟过程中控制多聚腺苷酸尾长度的遗传决定因素，这些因素与人类生育能力相关。	Xiang, K.	PDF	N/A	PAL-AI reveals genetic determinants that control poly(A)-tail length during oocyte maturation with relevance to human fertility
研究短链脂肪酸对结直肠癌中细胞外囊泡生成的影响	Macedo, D.	PDF	N/A	Investigating Short-Chain Fatty Acids Effects on Extracellular Vesicles Production in Colorectal Cancer
陆地蛞蝓Ambigolimax valentianus的耐寒性	Gill, L. T.	PDF	N/A	The cold tolerance of the terrestrial slug, Ambigolimax valentianus
适应毒物的北大西洋青鳉鱼（Fundulus heteroclitus）在低氧条件下基因表达和DNA甲基化变化	Aluru, N.	PDF	N/A	Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus)
人类巨噬细胞反应与L. (V.) panamensis对五价锑的自然抗性之间的相互作用	Fernandez, O. L.	PDF	N/A	Interplay of human macrophage response and natural resistance of L. (V.) panamensis to pentavalent antimony
胚胎肥大细胞来源于表达Cpa3的祖细胞，与粒细胞-单核细胞祖细胞无关	Ma, W.	PDF	N/A	Embryonic Mast Cells Arise from Cpa3-expressing Precursors Independent of Granulocyte-Monocyte Progenitors
一个PI3Kδ-Foxo1-FasL信号放大环路重新编排了CD4+辅助T细胞的信号传导、分化和表观遗传重塑	Golec, D. P.	PDF	N/A	A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T helper cell signaling, differentiation and epigenetic remodeling
灵活的、适用于生产规模的、在台式测序仪上进行的人类全基因组测序	Green, K.	PDF	N/A	FLEXIBLE, PRODUCTION-SCALE, HUMAN WHOLE GENOME SEQUENCING ON A BENCHTOP SEQUENCER
绘制人类结肠肠内分泌细胞所显示的可成药靶点	Lei, Y.	PDF	N/A	Mapping the druggable targets displayed by human colonic enteroendocrine cells
竞争、降水和温度塑造了miombo林冠异速生长律偏离缩放定律的形态	Yambayamba, A. M.	PDF	N/A	Competition, precipitation and temperature shape deviations from scaling laws in the crown allometries of miombo woodlands
按蚊幼虫在水生生态系统中的营养相互作用：一种宏基因组学方法	Karikari, A. S.	PDF	N/A	Trophic Interactions of Anopheles Gambiae Mosquito Larvae in Aquatic Ecosystem: A Metagenomics Approach
从图分析中得出的功能性重要残基：协同进化动态耦合	Xu, M.	PDF	N/A	Functionally Important Residues from Graph Analysis of Coevolved Dynamic couplings
栽培啤酒花（Humulus lupulus L.）的进化历史及其根际微生物群落组成	McElwee-Adame, A.	PDF	N/A	Evolutionary history and rhizosphere microbial community composition in domesticated hops (Humulus lupulus L.)
黑腹果蝇利用核结构来招募剂量补偿机制。	Sneideman, M. P. L.	PDF	N/A	Drosophila melanogaster employs nuclear architecture for recruitment of dosage compensation
组蛋白变体H2BE调控活动依赖性基因表达及稳态缩放	Feierman, E. R.	PDF	N/A	Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling
通过建模基因型与环境互作进行花生产量的基因组预测	Lubanga, N.	PDF	N/A	Genomic prediction by modelling genotype by environment interaction for yield in groundnut
核苷酸自组装的病理生理学意义：腺嘌呤衍生核苷酸在疾病机制中的聚集	Dave, R.	PDF	N/A	Pathophysiological Implications of Nucleotide Self-Assembly: Adenine-Derived Nucleotides Aggregation in Disease Mechanisms
多层次牙型多样性的整合将鲨鱼宏观进化模式与生态策略联系起来。	Zimm, R.	PDF	N/A	Integration of multi-level dental diversity links macro-evolutionary patterns to ecological strategies across sharks.
早期区域淋巴结激活可驱动祖先多样性人群中的流感疫苗反应	Siu, J. H.	PDF	N/A	Early regional lymph node activation drives influenza vaccine responses in an ancestrally diverse cohort
PIPENN-EMB：集成网络与蛋白质嵌入超越同源性推广蛋白质界面预测	Thomas, D. P. G.	PDF	N/A	PIPENN-EMB: ensemble net and protein embeddings generalise protein interface prediction beyond homology
在非靶向代谢组学中，是否进行缺失值填补——这就是组成性问题	Krutkin, D. D.	PDF	N/A	To impute or not to impute in untargeted metabolomics - that is the compositional question
癌症突变互斥性的贝叶斯建模	Czyz, P.	PDF	N/A	Bayesian modeling of mutual exclusivity in cancer mutations
PSTP：通过迁移学习和注意力机制解码蛋白质相分离的潜在序列语法	Feng, M.	PDF	N/A	PSTP: Decoding Latent Sequence Grammar through Transfer Learning and Attention for Protein Phase Separation
生成低密度最小化器	Golan, S.	PDF	N/A	Generating low-density minimizers
通过多模态深度学习预测细菌蛋白质功能	Muzio, G.	PDF	N/A	Bacterial protein function prediction via multimodal deep learning
通过链统计提高泛基因组分类准确性	Brown, N. K.	PDF	N/A	Improved pangenomic classification accuracy with chain statistics
缺氧诱导胰腺腺癌（PDAC）细胞系细胞表面的广泛蛋白质和蛋白水解重塑	Lui, I.	PDF	N/A	Hypoxia induces extensive protein and proteolytic remodeling of the cell surface in pancreatic adenocarcinoma (PDAC) cell lines
靶向PTP4A3的过度表达可增强HGSOC细胞对化疗药物的敏感性。	Lopez-Garza, A.	PDF	N/A	Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs.
# BioRxiv 2024-11-01 Papers

标题	作者	PDF链接	代码仓库	Title
在没有内侧前额叶皮层的情况下，行为的认知控制和海马信息处理	Park, E.	PDF	N/A	Cognitive control of behavior and hippocampal information processing without medial prefrontal cortex
硬皮病亚型中独特的T细胞染色质景观	Dou, D. R.	PDF	N/A	Distinct T cell chromatin landscapes in scleroderma subtypes
利用全基因组谱系估计扩散速率并定位遗传祖先	Osmond, M.	PDF	N/A	Estimating dispersal rates and locating genetic ancestors with genome-wide genealogies
个体在体验多样性方面的差异塑造了事件分割的粒度。	Hodgetts, C. J.	PDF	N/A	Individual differences in experiential diversity shape event segmentation granularity
光环：单细胞多组学数据的层次因果建模	Mao, H.	PDF	N/A	HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data
人类线粒体基因组编码一种干扰素应答的宿主防御肽	Rice, M. C.	PDF	N/A	The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide
利用Renoir绘制空间配体-靶标活性图	Rao, N.	PDF	N/A	Charting spatial ligand-target activity using Renoir
柳雷鸟种群的长期趋势与短期动态	Willebrand, T.	PDF	N/A	Long term trend and short-term dynamics of a willow grouse population
磷脂酰肌醇和小热休克蛋白对NRF2的调控	Chen, C.	PDF	N/A	Regulation of NRF2 by Phosphoinositides and Small Heat Shock Proteins
罕见的neurexin-1杂合缺失的表型复杂性	Fernando, M. B.	PDF	N/A	Phenotypic complexities of rare heterozygous neurexin-1 deletions
中介亚基Med4在乳腺癌中强制执行转移性休眠	Bae, S.-Y.	PDF	N/A	Mediator Subunit Med4 Enforces Metastatic Dormancy in Breast Cancer
单细胞转录组图谱揭示了急性髓系白血病中异常分化的遗传和非遗传决定因素	Zeng, A. G. X.	PDF	N/A	Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML
高分辨率分子动力学模拟：丙酮酸激酶肌肉同工酶1和2（PKM1/2）	Delobelle, Q.	PDF	N/A	High-resolution Molecular Dynamics Simulations of the Pyruvate Kinase Muscle Isoform 1 and 2 (PKM1/2)
一种用于建模蛋白质液-液相分离的变分图划分方法	Wang, G.	PDF	N/A	A Variational Graph Partitioning Approach to Modeling Protein Liquid-liquid Phase Separation
事件分割的神经基础：环境中的稳定特征通过神经状态得以反映	Oetringer, D.	PDF	N/A	The Neural Basis of Event Segmentation:Stable Features in the Environment areReflected by Neural States
通过双功能HSV载体治疗性疫苗清除慢性SIV感染猕猴中的病毒潜伏期	Wen, Z.	PDF	N/A	Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
抑制间接通路活性导致在帕金森病冲动控制障碍小鼠模型中出现异常决策行为	Zhuang, X.	PDF	N/A	Inhibition of Indirect Pathway Activity Causes Abnormal Decision-Making In a Mouse Model of Impulse Control Disorder in Parkinson's Disease
自动浮游生物监测表明，微型浮游动物和温度在预测浮游植物大小类群的动态变化中起着关键作用。	Merkli, S.	PDF	N/A	Automated plankton monitoring suggests a key role of microzooplankton and temperature for predicting dynamics of phytoplankton size classes
分子洞察：hERG激活剂对严重LQT2突变体的救援机制研究。	Kumawat, A.	PDF	N/A	Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations.
药物基因组学合成致死筛选揭示了NF1相关肿瘤的潜在脆弱性和新的治疗策略	Williams, K. B.	PDF	N/A	Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors
微切割肿瘤立方体：一种保留复杂肿瘤微环境的微尺度癌症模型，适用于大规模测试	Horowitz, L. F.	PDF	N/A	Microdissected tumor cuboids: a microscale cancer model for large-scale testing that retains a complex tumor microenvironment
在发病率高的地区，持续的跨物种传播系统主导了产志贺毒素大肠杆菌O157:H7的流行病学：一项基因组流行病学研究	Tarr, G. A. M.	PDF	N/A	Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: a genomic epidemiology study
串联重复蛋白为工程生物分子凝聚体引入了可调的特性。	Ng, T. L. C.	PDF	N/A	Tandem-repeat proteins introduce tuneable properties to engineered biomolecular condensates
人类在短暂先天视觉剥夺后视觉皮层兴奋/抑制比率的改变	Pant, R.	PDF	N/A	Altered visual cortex excitatory/inhibitory ratio following transient congenital visual deprivation in humans
筛选大猩猩博物馆标本中的DNA病毒	Haemmerle, M.	PDF	N/A	Screening great ape museum specimens for DNA viruses
使用基于Shapley值的特征子集选择方法识别区分旁系同源蛋白的关键氨基酸类型	Machingal, P.	PDF	N/A	Identifying key amino acid types that distinguish paralogous proteins using Shapley value based feature subset selection
LETSmix：一种空间感知且基于学习的领域自适应方法，用于空间转录组学中的细胞类型反卷积	Zhan, Y.	PDF	N/A	LETSmix: a spatially informed and learning-based domain adaptation method for cell-type deconvolution in spatial transcriptomics
前额叶5α-还原酶2介导雄性特异的急性应激反应	Cadeddu, R.	PDF	N/A	Prefrontal 5α-reductase 2 mediates male-specific acute stress response
一种新型进食机制：太阳鸟通过舌内吸吮的方式饮用花蜜	Cuban, D.	PDF	N/A	A novel feeding mechanism: Sunbirds drink nectar via intralingual suction
使用可穿戴、免手持系统对体外病原菌中卟啉特异性荧光进行成像	Sun, J.	PDF	N/A	Imaging of porphyrin-specific fluorescence in pathogenic bacteria in vitro using a wearable, hands-free system
使用可解释的非结构化元数据建模对公开可用的样本和研究进行标注	Yuan, H.	PDF	N/A	Annotating publicly-available samples and studies using interpretable modeling of unstructured metadata
水网络中的熵变促进蛋白质变性	Wang, Y.	PDF	N/A	Entropy Changes in Water Networks Promote Protein Denaturation
功能性适应的大脑结构基集：一种动态融合方法	Duda, M.	PDF	N/A	Functionally Adaptive Structural Basis Sets of the Brain: A Dynamic Fusion Approach
前额叶皮层和腹侧海马核伏隔核输入的奖励整合协同调节参与度	Iyer, E. S.	PDF	N/A	Reward integration in prefrontal-cortical and ventral-hippocampal nucleus accumbens inputs cooperatively modulates engagement
哈茨木霉T22诱导根瘤菌和类黄酮驱动的共生关系，促进豌豆对缺铁的耐受性。	Thapa, A.	PDF	N/A	Trichoderma afroharzianum T22 induces rhizobia and flavonoid-driven symbiosis to promote iron deficiency tolerance in garden pea
在成年功能连接网络中，大脑区域的一个子集在早期发育过程中表现出高度的可靠性。	Tu, J. C.	PDF	N/A	A subset of brain regions within adult functional connectivity networks demonstrate high reliability across early development
plectin介导的细胞骨架串扰作为抑制肝细胞癌生长和转移的靶点。	Outla, Z.	PDF	N/A	Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis.
开发一种免疫分析方法用于检测和诊断由产甲烷古菌引起的微生物诱导腐蚀	Lahme, S.	PDF	N/A	Development of an immunoassay for the detection and diagnosis of microbially-influenced corrosion caused by methanogenic Archaea
使用深度学习在冷冻电镜和X射线图中识别配体	Karolczak, J.	PDF	N/A	Ligand Identification in CryoEM and X-ray Maps Using Deep Learning
生物学约束的脉冲神经网络用于脊髓损伤后运动功能恢复的神经调节	Chia, R.	PDF	N/A	Biologically-Constrained Spiking Neural Network for Neuromodulation in Locomotor Recovery after Spinal Cord Injury
结合骑行性高温与紫锥菊苷对胰腺癌细胞PANC-1产生协同治疗效果	Chen, W.-T.	PDF	N/A	Combination of cycling hyperthermia and Echinacoside creates synergistic curing effect on pancreatic cancer PANC-1 cells
针对牛繁殖失败相关病原体的靶向综合下一代测序面板，用于同时检测病原体。	Periyasamy, D.	PDF	N/A	Targeted syndromic next-generation sequencing panel for simultaneous detection of pathogens associated with bovine reproductive failure
不仅仅是果香：番荔枝科植物的花部生物学、香气和光谱反射率	Liu, M.-F.	PDF	N/A	More than fruity scents: floral biology, scent and spectral reflectance of Annonaceae species
使用HarmoDecon缓解空间分辨转录组学中细胞类型反卷积的多尺度偏差	Wang, Z.	PDF	N/A	Mitigation of multi-scale biases in cell-type deconvolution for spatially resolved transcriptomics using HarmoDecon
纹状体侧向抑制调节左旋多巴诱发运动障碍小鼠模型中的动作选择	Twedell, E. L.	PDF	N/A	Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia
NAD的二核苷酸结构使其能够在矿物表面上进行特定的还原作用。	Pereira, D. P. H.	PDF	N/A	The dinucleotide structure of NAD enables specific reduction on mineral surfaces
阴离子脂质对阴离子交换蛋白1（AE1）构象转变能量景观的影响	Chen, T.	PDF	N/A	Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1)
鉴定和表征从淡水斑马贻贝（Dreissena bugensis）中提取的一种湿粘蛋白	Obille, A. R.	PDF	N/A	Identification and characterization of a wet adhesive protein extracted from Dreissena bugensis, the freshwater quagga mussel
丝裂霉素C与低剂量甲硝唑联合使用对艰难梭菌感染及其复发具有协同预防作用	Gong, J.-J.	PDF	N/A	Combination of mitomycin C and low-dose metronidazole synergistically against Clostridioides difficile infection and recurrence prevention
研究Huntingtin蛋白的Nt17结构域的曲率感应	Nanajkar, N.	PDF	N/A	Investigating curvature sensing by the Nt17 domain of Huntingtin protein
TFAM作为UVC诱导的线粒体DNA损伤的传感器	King, D. E.	PDF	N/A	TFAM as a sensor of UVC-induced mitochondrial DNA damage
生长素-水杨酸跷跷板调控植物生长与食草动物防御之间的年龄依赖性平衡	Han, W.-H.	PDF	N/A	Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense
ProteinWeaver：一个用于可视化本体注释蛋白质网络的网络工具	Anderson, O. F.	PDF	N/A	ProteinWeaver: A Webtool to Visualize Ontology-Annotated Protein Networks
Neuroligin 3 突显了果蝇社交距离中的性别二态性电路	Robinson, J. W.	PDF	N/A	Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing
CFC-seq：全长加帽RNA的鉴定揭示增强子来源的转录	Yip, C. W.	PDF	N/A	CFC-seq: identification of full-length capped RNAs unveil enhancer-derived transcription
TIPP3 和 TIPP3-fast：改进的宏基因组丰度分析	Shen, C.	PDF	N/A	TIPP3 and TIPP3-fast: Improved Abundance Profiling in Metagenomics
小鼠、猕猴和人类中一致的单神经元时间尺度层次结构	Zeisler, Z. R.	PDF	N/A	Consistent hierarchies of single-neuron timescales in mice, macaques and humans
基底神经节和小脑回路在运动学习期间丘脑的整合作用	Roth, R. H.	PDF	N/A	Thalamic integration of basal ganglia and cerebellar circuits during motor learning
在假定的敏感期，青少年的前额叶皮层比成年人表现出更强的群体水平信息编码能力。	Klinger, M.	PDF	N/A	The adolescent frontal cortex shows stronger population-level encoding of information than the adult during a putative sensitive period
产前应激通过损害胎盘的糖皮质激素屏障功能，增加了后代皮质酮的水平。	Liu, C.	PDF	N/A	Prenatal stress increases corticosterone levels in offspring by impairing placental glucocorticoid barrier function
预测的受限可及区域标记调控元件和因果变异	Tomizuka, K.	PDF	N/A	Predicted constrained accessible regions mark regulatory elements and causal variants
齿状回去甲肾上腺素渐增促进厌恶情境加工	Zhang, E. T.	PDF	N/A	Dentate Gyrus Norepinephrine Ramping Facilitates Aversive Contextual Processing
新环境暴露驱动了海马体中时间定义和区域特异性的染色质可及性和基因表达变化	Duffy, E. E.	PDF	N/A	Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampus
三重标记通过三色单分子FRET解析GPCR的中间状态	Bonhomme, L.	PDF	N/A	Triple labeling resolves a GPCR intermediate state by 3-color single molecule FRET
内在无序蛋白质内部基于电荷的瞬时相互作用的结构和功能相关性	Wohl, S.	PDF	N/A	Structural and Functional Relevance of Charge Based Transient Interactions inside Intrinsically Disordered Proteins
H1和H3血凝素跨膜结构域以不同方式参与膜融合	Borkowska, P.	PDF	N/A	Transmembrane domains of H1 and H3 hemagglutinin contribute to membrane fusion in a different manner
从分子动力学模拟中学习Gα蛋白的变构相互作用	Yu, Y.	PDF	N/A	Learning allosteric interactions in Gα proteins from molecular dynamics simulations
COCOMO2：一种用于相互作用的折叠和无序蛋白质的粗粒度模型	Jussupow, A.	PDF	N/A	COCOMO2: A coarse-grained model for interacting folded and disordered proteins
通过质谱和反相蛋白阵列分析的全蛋白质组、磷酸蛋白质组和糖蛋白质组的泛癌细胞系全景图	Shi, W.	PDF	N/A	The Whole Proteome, Phosphoproteome, and Glycoproteome Landscape of Pan-Cancer Cell Lines Profiled by Mass Spectrometry and Reverse Phase Protein Array
一种针对RSV和hMPV融合糖蛋白抗原位点V的中和性和保护性人类抗体	Abu-Shmais, A. A.	PDF	N/A	A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein
mGluR6先天性静止性夜盲突变体的糖基化缺陷及与ELFN1的结合异常	Pindwarawala, M.	PDF	N/A	Defective glycosylation and ELFN1 binding of mGluR6 congenital stationary night blindness mutants
代谢调控糖基化形式以建立糖基依赖的蛋白质相互作用网络	Liu, X.	PDF	N/A	Metabolic Control of Glycosylation Forms for Establishing Glycan-Dependent Protein Interaction Networks
通过引导AlphaFold2利用距离分布建模蛋白质构象。应用于双电子电子共振（DEER）光谱学。	Wu, T.	PDF	N/A	Modeling Protein Conformations by Guiding AlphaFold2 with Distance Distributions. Application to Double Electron Electron Resonance (DEER) Spectroscopy.
结构环境调节α-突触核蛋白内在无序氨基末端的构象集合	Dumarieh, R.	PDF	N/A	Structural context modulates the conformational ensemble of the intrinsically disordered amino terminus of α-synuclein
在认知需求增加时，齿状回的局部活动会增强。	Castillon, C.	PDF	N/A	Subregional activity in the dentate gyrus is amplified during elevated cognitive demands
细菌中一种非常规G蛋白复合物对细胞极性的调控	Mignot, T.	PDF	N/A	Cell polarity control by an unconventional G-protein complex in bacteria
巴基斯坦旁遮普省生产的面包废料对罗非鱼幼鱼的表观消化率和营养表现	Hussain, S. S.	PDF	N/A	Apparent digestibility and nutritional performance of bakery waste produced in Punjab Pakistan for Labeo rohita fingerlings
脂质运输Mla Pqi嵌合系统对布鲁氏菌在巨噬细胞中的生存至关重要	Lannoy, A.	PDF	N/A	A lipid transport Mla Pqi Chimeric system is essential for Brucella abortus survival in macrophages
全基因组研究大肠杆菌外膜蛋白家族在马赛克进化中的情况	Cao, X.	PDF	N/A	Genome-wide investigation of outer membrane protein families under mosaic evolution in Escherichia coli
合成磁性纳米颗粒的生物功能化涂层能够实现对细胞内蛋白质功能的磁遗传控制。	Kappen, M.	PDF	N/A	Biofunctional coating of synthetic magnetic nanoparticles enables magnetogenetic control of protein functions inside cells
cryoMDM：基于噪声冷冻电镜单颗粒图像的分子模拟驱动结构匹配方法，用于估计多种原子三维模型。	Tokuhisa, A.	PDF	N/A	cryoMDM; Molecular simulation Driven structural Matching Approach to Estimate Variety of Atomic Three-dimensional Model Based on Noisy cryoEM Single Particle Images.
全原子模拟阐明了RNA与膜相互作用的分子机制	Di Marco, S.	PDF	N/A	All-atom simulations elucidate the molecular mechanismunderlying RNA-membrane interactions
系统性抑制从头嘌呤生物合成通过增加产热和减少食物摄入，防止体重增加并改善代谢健康。	Myers, J. W.	PDF	N/A	Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake
软X射线断层扫描的自动分割：在酵母全细胞定量成像中实现高通量下亚微米分辨率的天然细胞结构	Chen, J.-H. F.	PDF	N/A	Automated segmentation of soft X-ray tomography: native cellular structure with sub-micron resolution at high throughput for whole-cell quantitative imaging in yeast
直接胰岛素分泌发生在具有最佳ELKS含量的精确皮层区域，这些区域缺乏微管结构。	Fye, M. A.	PDF	N/A	Directed insulin secretion occurs at precise cortical regions with optimal ELKS content that are devoid of microtubules
有机组织结构是预测气道模型中全氟碳化合物暴露结果的必要条件。	Liu, S. W.	PDF	N/A	Organotypic tissue architecture is a requisite for predictive outcomes of perfluorocarbon exposure in airway models
来自组织微环境的Tenascin-C通过Annexin A2促进肌肉干细胞自我更新。	Loreti, M.	PDF	N/A	Tenascin-C from the tissue microenvironment promotes muscle stem cell self-renewal through Annexin A2
改变肾脏血管模式可减轻缺血性肾损伤，并限制与衰老相关的血管损失	McLarnon, S. R.	PDF	N/A	Altered renal vascular patterning reduces ischemic kidney injury and limits vascular loss associated with aging
最佳竞争者：互利共生者（如传粉者）的吸引力与选择之间的平衡推动了促进作用，并可能促进作物传粉。	Dornhaus, A.	PDF	N/A	Optimal competitors: the balance of attraction and choices of mutualists, like pollinators, drives facilitation and may promote crop pollination
通过微调蛋白质和小分子语言模型学习结合亲和力	Gorantla, R.	PDF	N/A	Learning Binding Affinities via Fine-tuning of Protein and Ligand Language Models
波形蛋白与nesprin-3的分子连接通过细胞几何约束增强了细胞核的变形	Swoger, M.	PDF	N/A	Vimentin molecular linkages with nesprin-3 enhance nuclear deformation by cell geometric constraints
单个细胞能够感知分等级的刺激	Kramar, M.	PDF	N/A	Single cells can resolve graded stimuli
通过K函数分析揭示的细胞竞争的空间和时间特征	Day, N.	PDF	N/A	Spatial and temporal signatures of cell competition revealed by K-function analysis
壳聚糖纳米胶囊与非洲鸭脚木提取物对Wistar大鼠的免疫系统具有调节作用	Nyuyfoni, G. F.	PDF	N/A	Chitosan nanocapsules with Alstonia boonei extract modulate the immune system in Wistar rats
纳米生理学方法揭示了斑马鱼视网膜双极带状突触中钙微域的多样性	Rameshkumar, N.	PDF	N/A	Nanophysiology Approach Revealed Diversity in Calcium Microdomains in Zebrafish Retinal Bipolar Ribbon Synapses
铜宫内节育器对减少母马子宫感染的测试：一项初步研究	Gradil, C.	PDF	N/A	The Testing of Copper Intrauterine Devices to Mitigate Uterine Infections in Mares: A Preliminary Study
用于细胞表面交叉光学和化学标记的工具	Innes-Gold, S.	PDF	N/A	Tools for intersectional optical and chemical tagging on cell surfaces
可变剪接调节染色质互作组及RIF1 C端结构域的相分离	Koo, A. S.-H.	PDF	N/A	Alternative splicing modulates chromatin interactome and phase separation of the RIF1 C-terminal domain
LARP4的短保守区域-2与核糖体相关蛋白RACK1相互作用，并促进翻译过程。	Ranjan, A.	PDF	N/A	The short conserved region-2 of LARP4 interacts with ribosome-associated RACK1 and promotes translation
复制体通过黏连蛋白环的过程	Glaser, S.	PDF	N/A	Replisome passage through the cohesin ring
一种新型微型丝状噬菌体作为基因递送载体靶向哺乳动物细胞	Wong, S.	PDF	N/A	A novel miniaturized filamentous phagemid as a gene delivery vehicle to target mammalian cells
链球菌噬菌体基因组揭示了广泛的多样性、新的分类学见解以及源自内溶素的全新抗菌肽	Mondal, S. I.	PDF	N/A	Streptococcus Phage Genomes Reveal Extensive Diversity, New Taxonomic Insights, and Novel Endolysin-Derived Antimicrobial Peptides
新见解：洛蒙丝孢菌（Lomentospora prolificans）黑色素结构	Liporagi Lopes, L.	PDF	N/A	New Insights Into The Melanin Structure Of Lomentospora prolificans
EasyAb：一种基于抗体的高通量工作流程，用于与质谱联用的PTM肽富集方法	Jayavelu, A. K.	PDF	N/A	EasyAb: A High-Throughput Workflow for Antibody-Based PTM Peptide Enrichment Method Coupled to Mass Spectrometry
高吞吐量活细胞单细胞蛋白质组学	Karagach, S.	PDF	N/A	High throughput single-cell proteomics of in-vivo cells
由脂质过氧化产生的N-醛基修饰磷脂酰乙醇胺是N-酰基磷脂酰乙醇胺磷脂酶D的强效底物。	Fadaei, R.	PDF	N/A	N-Aldehyde-Modified Phosphatidylethanolamines generated by lipid peroxidation are robust substrates of N-Acyl Phosphatidylethanolamine Phospholipase D
非经典GPCR信号转导在Hedgehog通路中的结构机制	Steiner, W. P.	PDF	N/A	A Structural Mechanism for Noncanonical GPCRSignal Transduction in the Hedgehog Pathway
一种定量细胞内肽结合分析揭示了短线性基序的识别决定因素及其上下文依赖性	Subbanna, M. S.	PDF	N/A	A quantitative intracellular peptide binding assay reveals recognition determinants and context dependence of short linear motifs
伪GTP酶介导的蛋白质-蛋白质相互作用的结构基础	Wang, B.	PDF	N/A	Structural basis of pseudoGTPase-mediated protein-protein interactions
哺乳动物黑视蛋白与拮抗剂AA92593特异性相互作用的分子基础	Obayashi, K.	PDF	N/A	Molecular basis underlying specific interaction of mammalian melanopsins with an antagonist AA92593
通过魔角旋转核磁共振技术获得的噬菌体P22衣壳蛋白在原衣壳中的结构模型	Guo, C.	PDF	N/A	Structural Model of Bacteriophage P22 Scaffolding Protein in a Procapsid by Magic-Angle Spinning NMR
Notch信号阻断将静息神经干细胞的转录组异质性与它们的再激活途径及潜能联系起来。	Morizet, D.	PDF	N/A	Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with their reactivation routes and potential
在物体处理过程中，反馈信号中的高阶和低阶特征具有不同的目标、动态变化和功能	Hou, W.	PDF	N/A	Differential destinations, dynamics, and functions of high- and low-order features in the feedback signal during object processing
通过通信子空间在大规模新皮层模型中进行认知网络交互	Pereira-Obilinovic, U.	PDF	N/A	Cognitive networks interactions through communication subspaces in large-scale models of the neocortex
病毒载体介导的SLC9A6基因替代减少了Christianson综合征摇晃大鼠模型中的小脑功能障碍	Anderson, C. J.	PDF	N/A	Viral vector-mediated SLC9A6 gene replacement reduces cerebellar dysfunction in the shaker rat model of Christianson syndrome
大脑功能连接，而非神经解剖结构，捕捉到了青春期前性别与性别的相互关系。	Metoki, A.	PDF	N/A	Brain functional connectivity, but not neuroanatomy, captures the interrelationship between sex and gender in preadolescents
同时对小鼠皮层活动进行介观测量与操控	Matveev, P.	PDF	N/A	Simultaneous mesoscopic measurement and manipulation of mouse cortical activity
顺序规划的整合	Vikbladh, O. M.	PDF	N/A	Consolidation of Sequential Planning
在SH-SY5Y细胞中DJ-1缺陷揭示了涉及神经功能和疾病的基因和通路网络失调	Gock, N.	PDF	N/A	DJ-1 deficiency in SH-SY5Y cells reveals dysregulated networks of genes and pathways involved in neuronal function and disease
线粒体NADK2依赖的NADPH调控人类神经元中Tau寡聚体的摄取	Pardo, E. C.	PDF	N/A	Mitochondrial NADK2-dependent NADPH controls Tau oligomer uptake in human neurons
伦敦出租车司机利用区域边界来优化路线选择，并在三十年的时间内提升他们的导航技能。	Gahnstrom, C. J.	PDF	N/A	London taxi drivers leverage regional boundaries to optimise route choices and improve their navigation skill across three decades
DJ-1 介导帕金森病星形胶质细胞和胶质母细胞瘤细胞中代谢和免疫反应的调控	Mencke, P.	PDF	N/A	DJ-1 mediates regulation of metabolism and immune response in Parkinsons disease astrocytes and Glioblastoma cells
急性及早期应激轴调节在关节疾病中能永久性地减轻疼痛和情感共病	Hestehave, S.	PDF	N/A	Acute and early stress axis modulation in joint disease permanently reduces pain and emotional comorbidities
两种方法和时间尺度表明，水中珊瑚疾病治疗并未促进抗生素抗性的发展。	Neely, K. L.	PDF	N/A	Two methodologies and timescales show no promotion of antibiotic resistance from in-water coral disease treatments
适应性实验室进化产生的耐粘菌素铜绿假单胞菌菌株中，PmrB传感器激酶的适应性权衡及新错义突变的发现	Padhy, I.	PDF	N/A	Fitness trade-off and the discovery of a novel missense mutation in the PmrB sensor kinase of a colistin-resistant Pseudomonas aeruginosa strain developed by adaptive laboratory evolution
新型共生生物揭示阿米巴原虫是环境衣原体的重要宿主	Liu, F.	PDF	N/A	Novel symbionts reveal amoebae as significant hosts for environmental chlamydiae
利用基于活性的蛋白质谱分析筛选化疗诱导外周神经病变大鼠模型中的潜在生物标志物	Miao, H.	PDF	N/A	Screening of potential biomarkers using activity-based protein profiling in a rat model of chemotherapy-induced peripheral neuropathy
季风影响下的两条印度城市河流中抗生素抗性的驱动因素，这些河流接收未经处理的废水	Bagra, K.	PDF	N/A	Drivers of antibiotic resistance in two monsoon-impacted Indian urban rivers receiving untreated wastewater
小梁网单细胞分析鉴定出青光眼模型中的线粒体功能障碍，该功能障碍可通过维生素B3治疗得到保护	Tolman, N.	PDF	N/A	Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment
利用差示扫描量热法数据对两态蛋白质转变的标准拟合技术的显式推导	Priklopil, T.	PDF	N/A	Explicit derivation of the standard fitting technique for two-state protein transitions using differential scanning calorimetry data
动脉平滑肌细胞中自噬介质Parkin的缺乏会加剧腹主动脉瘤的形成。	Wang, H.	PDF	N/A	Deficiency of mitophagy mediator Parkin in aortic smooth muscle cells exacerbates abdominal aortic aneurysm
一种基于大肠杆菌的平台，用于环状病毒载体的生产和组装	Prakash, R.	PDF	N/A	An E. coli-based platform for the production and assembly of anellovirus vectors
心脏管形态发生受MEF2C调控的节段特异性基因调控网络的调节。	Muncie-Vasic, J. M.	PDF	N/A	Heart tube morphogenesis is regulated by segment-specific gene regulatory networks controlled by MEF2C
啮齿动物牙齿发育的多模态表征	Jiang, Y.	PDF	N/A	Multi-modal characterization of rodent tooth development
鸟类前肠的延长需要内在和外在细胞行为的协调。	Powell, O.	PDF	N/A	Elongation of the nascent avian foregut requires coordination of intrinsic and extrinsic cell behaviors
TFAP2C是子宫内滋养层细胞侵袭和深部血绒毛膜胎盘形成的关键调节因子。	Dominguez, E. M.	PDF	N/A	TFAP2C is a key regulator of intrauterine trophoblast cell invasion and deep hemochorial placentation
稀疏动物社会网络分析	Mylne, H. K.	PDF	N/A	Analysis of sparse animal social networks
通过胞外囊泡非经典分泌自噬相关蛋白VMP1作为胰腺细胞损伤潜在生物标志物	Tadic, M. S.	PDF	N/A	UNCONVENTIONAL SECRETION OF THE AUTOPHAGY-RELATED PROTEIN VMP1 VIA EXTRACELLULAR VESICLES AS A POTENTIAL BIOMARKER FOR PANCREATIC CELL INJURY
BamE的N端延伸区域协调BamA的β-桶域与BamD之间的相互作用，以实现高效组装。	Maruno, Y.	PDF	N/A	The N-terminal extension region of BamE coordinates interaction between the β-barrel domain of BamA and BamD for efficient assembly
基于去稳定剂的细菌微隔室壳体外快速组装与装载方法	Range, K. L.	PDF	N/A	A chaotrope-based approach for rapid in vitro assembly and loading of bacterial microcompartment shells
腹侧被盖区与人类的风险厌恶行为之间的功能耦合	Lin, W.	PDF	N/A	Habenula-ventral tegmental area functional coupling and risk-aversion in humans
灵长类视网膜输出中的功能多样性	Kling, A.	PDF	N/A	Functional diversity in the output of the primate retina
星形胶质细胞控制人类皮层网络中的UP状态和慢振荡周期性	Crowe, J. A.	PDF	N/A	Astrocytes control UP state and slow oscillation periodicity in human cortical networks
线粒体应激通过蛋白水解激活PKCδ和Lamin B1磷酸化，在神经元细胞中解构核结构：与年龄相关性神经退行性疾病发病机制的关联	Charli, A.	PDF	N/A	Mitochondrial Stress Disassembles Nuclear Architecture through Proteolytic Activation of PKCδ and Lamin B1 Phosphorylation in Neuronal Cells: Implications for Pathogenesis of Age-related Neurodegenerative Diseases
从果蝇连接组到精确的环吸引子动力学	Biswas, T.	PDF	N/A	From the fly connectome to exact ring attractor dynamics
雄性和雌性大鼠在精神兴奋剂自我给药行为方面的最显著差异与生物性别无关。	Showell, B. H.	PDF	N/A	The most significant differences between male and female rats regarding psychostimulant self-administration behavior are unrelated to biological sex
使用结合通道停用策略和可变数量动态聚焦通道的成人耳蜗植入者的噪音中言语表现	Wohlbauer, D. M.	PDF	N/A	Speech in noise performance in adults with cochlear implants using a combined channel deactivation strategy with a variable number of dynamic focused channels
电休克疗法在发作后产生了一股隐秘的浪潮	Rosenthal, Z.	PDF	N/A	Electroconvulsive therapy generates a hidden wave after seizure
偏倚校正元分析克服了小脑忽视，以优化小脑行为地形图	Magielse, N.	PDF	N/A	Bias-accounting meta-analyses overcome cerebellar neglect to refine the cerebellar behavioral topography
侧化的结状神经节基因表达暗示了胆囊收缩素受体在体内奖励信号传导中的作用	Welch, H. F.	PDF	N/A	Lateralized nodose ganglia gene expression implicates cholecystokinin receptors in interoceptive reward signaling
在长期增强过程中，突触前囊泡簇从紧密组织转变为松散组织。	Garcia, G. C.	PDF	N/A	The presynaptic vesicle cluster transitions from a compact to loose organization during long-term potentiation
Tcf4缺乏导致小鼠反复发作癫痫	Craciun, L.	PDF	N/A	Tcf4 Deficiency Causes Recurrent Seizures in Mice
每日电场治疗可改善大鼠胸椎挫伤脊髓损伤后的功能结果	Harland, B.	PDF	N/A	Daily electric field treatment improves functional outcomes after thoracic contusion spinal cord injury in rats
神经同步性对于语音理解来说是“足够好”的。	Rafferty, M. B.	PDF	N/A	Neural synchrony is "good enough" for speech comprehension
背景很重要：整合NMDA受体功能障碍揭示了在小鼠模型中携带人类患者GluN1变异的有效癫痫治疗方法	Venkatesan, S.	PDF	N/A	Context matters: Integrative NMDA receptor dysfunction reveals effective seizure treatment in mice with a human patient GluN1 variant
高效采样PROTAC诱导的三元复合物	Zhao, H.	PDF	N/A	Efficient Sampling of PROTAC-Induced Ternary Complexes
母体Med12保护滋养层多能性和胎盘发育	Halstead, M. M.	PDF	N/A	Maternal Med12 safeguards trophoblast pluripotency and placental development
钙瞬变调控多纤毛细胞在爪蟾皮肤发育中的上皮整合。	Christodoulou, N.	PDF	N/A	Calcium transients regulate epithelial integration of multiciliated cells during Xenopus skin development.
RNA结合蛋白Khdrbs1通过剪接调控造血干细胞和祖细胞的出现	Karp, I.	PDF	N/A	RNA Binding Protein Khdrbs1 Regulates Hematopoietic Stem and Progenitor Cell Emergence via Splicing
小蜂Nasonia vitripennis中异常巨大的种系决定因子的结构与组成	Kemph, A.	PDF	N/A	Novel structure and composition of the unusually large germline determinant of the wasp Nasonia vitripennis
简化胎鼠影像中的不对称量化：基于专家指导的半自动化流程	Rolfe, S. M.	PDF	N/A	Streamlining Asymmetry Quantification in Fetal Mouse Imaging: A Semi-Automated Pipeline Supported by Expert Guidance
嗅觉系统中Prok2下游基因的时空调控：从发育到功能	Kim, B.-R.	PDF	N/A	Spatiotemporal regulation by downstream genes of Prok2 in olfactory system: from development to function
宿主遗传背景而非环境对扁卷螺（Bulinus truncatus）的微生物群构成具有更大影响，扁卷螺是血吸虫属物种的中间宿主。	Jaquet, M. J.	PDF	N/A	Evidences that host genetic background more than the environment shapes the microbiota of the snail Bulinus truncatus, an intermediate host of Schistosoma species.
鲸鱼语言模型：利用机器学习在抹香鲸的声音和行为中寻找结构与信息	Sharma, P.	PDF	N/A	WhaleLM: Finding Structure and Information in Sperm Whale Vocalizations and Behavior with Machine Learning
通过mRNA递送对人类造血干细胞进行体内基因编辑以治疗血液疾病	Xu, S.	PDF	N/A	In vivo genome editing of human hematopoietic stem cells for treatment of blood disorders by mRNA delivery
系统性剖析正常乳腺组织中的表观遗传年龄加速现象，揭示其与雌激素信号传导及癌症风险的关联	Sehl, M. E.	PDF	N/A	Systematic dissection of epigenetic age acceleration in normal breast tissue reveals its link to estrogen signaling and cancer risk
抗寄生虫苯二氮卓类药物美克洛嗪对曼氏血吸虫转录表型的影响	Henthorn, C. R.	PDF	N/A	Transcriptional phenotype of the anti-parasitic benzodiazepine meclonazepam on the blood fluke Schistosoma mansoni
全鼠肾小球纳米级光学成像、重建与空间分析	Ali, A.	PDF	N/A	Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse Glomeruli
拟议的普遍存在于超微细菌门Patescibacteriota phyl. nov.中的新属Patescibacterium danicum gen. nov., sp. nov.	Dutkiewicz, Z.	PDF	N/A	Proposal of Patescibacterium danicum gen. nov., sp. nov. in the ubiquitous ultrasmall bacterial phylum Patescibacteriota phyl. nov.
精氨酸及其代谢在TGF-β诱导的肺成纤维细胞激活中的作用	Hamanaka, R. B.	PDF	N/A	Role of Arginine and its Metabolism in TGF-β-Induced Activation of Lung Fibroblasts
互养网络结构影响生长抑制压力下的微生物群落多样性	Newton, D. P.	PDF	N/A	The network structure of cross-feeding impacts microbial community diversity under growth-inhibiting stresses
结合系统发育和地理数据可以高度准确地预测植物-害虫相互作用	Hernandez-Gutierrez, E.	PDF	N/A	Combined phylogenetic and geographic data can predict plant-pest interactions with high accuracy
三萜环化酶的进化历史和现代多样性	McShea, H.	PDF	N/A	The evolutionary history and modern diversity of triterpenoid cyclases
古代二倍体栽培棉种草棉（Gossypium herbaceum L.）和亚洲棉（G. arboreum L.）的传播模式对比	Viot, C. R.	PDF	N/A	Contrasting dissemination patterns of diploid cultivated cotton species Gossypium herbaceum L. and G. arboreum L. in Antiquity
在宿主多样化的环境中克雷伯氏菌噬菌体的进化策略	Ferriol-Gonzalez, C.	PDF	N/A	Evolutionary strategies of Klebsiella phages in a host-diverse environment
基因组证据表明，蝾螈中的平衡致死系统起源于一次瞬间的物种形成事件。	France, J. M.	PDF	N/A	Genomic evidence suggests the balanced lethal system in Triturus newts originated in an instantaneous speciation event.
特质冗余和信息内容对人类系统发育推断的影响	Raskin, L. Y.	PDF	N/A	The effects of trait redundancy and information content on hominin phylogenetic inference
入侵阿根廷蚁（Linepithema humile）的群体基因组学——尽管遗传多样性低，引入的超群体中仍存在适应性进化	Holmberg, I.	PDF	N/A	Population Genomics of the Invasive Argentine Ant (Linepithema humile) - Adaptive Evolution in the Introduced Supercolonies Despite Low Genetic Diversity
巢寄生中的极端疲劳抗性类似于与宿主之间的乞食竞争中的消耗战	Antonson, N. D.	PDF	N/A	Extreme fatigue-resistance in a brood parasite parallels a war of attrition in begging competition with hosts
合成USC-093及其对映体前体USC-093D在体外及叙利亚仓鼠模型中对抗腺病毒的效果比较	Yang, J.	PDF	N/A	Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model
吸收分子使活体小鼠的腹部和背部都变得透明	TIE, X.	PDF	N/A	Absorbing molecules make both abdomen and back transparent in live mice
PMAIP1介导的葡萄糖代谢及其对乳腺癌肿瘤微环境的影响：多组学分析与实验验证的整合	Zhang, Y.	PDF	N/A	PMAIP1-Mediated Glucose Metabolism and its Impact on the Tumor Microenvironment in Breast Cancer: Integration of Multi-Omics Analysis and Experimental Validation
通过注意力增强的表征学习探索表型相关的单细胞	Wu, Q.	PDF	N/A	Exploring phenotype-related single-cells through attention-enhanced representation learning
TeloSearchLR：一种利用长序列读取检测新端粒重复基序的算法	Chung, G.	PDF	N/A	TeloSearchLR: an algorithm to detect novel telomere repeat motifs using long sequencing reads
FOXM1调控血小板诱导的胰腺癌细胞失巢凋亡抵抗	Ernesti, A.	PDF	N/A	FOXM1 regulates platelet-induced anoikis resistance in pancreatic cancer cells
细菌无细胞DNA分析显示，疑似败血症的新生马驹中多种细菌共同升高	Chen, L.-T.	PDF	N/A	Bacterial cell-free DNA profiling reveals co-elevation of multiple bacteria in newborn foals with suspected sepsis
基于微针的DNA提取实现无损种子基因型鉴定	Li, M.	PDF	N/A	Nondestructive Seed Genotyping via Microneedle-Based DNA Extraction
DANGEROUS MIX 3（一种α/β水解酶）触发植物中NLR介导的遗传不相容性的结构决定因素	Kim, G.	PDF	N/A	Structure determinants of DANGEROUS MIX 3, an alpha/beta hydrolase, for triggering NLR-mediated genetic incompatibility in plants
基于基因的适应性和碳同化能力在不同大果栎种群间的变异	Rea, L. M. S.	PDF	N/A	Genetically based variation in fitness and carbon assimilation among bur oak populations
NuclampFISH技术能够基于核RNA表达进行细胞分选，以用于染色质分析。	Liu, Y.	PDF	N/A	NuclampFISH enables cell sorting based on nuclear RNA expression for chromatin analysis
分享聚光灯：揭示跨物种的共同注意力动态	Glukhova, M.	PDF	N/A	Sharing the Spotlight: Uncovering common attentional dynamics across species
SenSeqNet：一种基于深度学习的蛋白质序列细胞衰老检测框架	Jiang, H.	PDF	N/A	SenSeqNet: A Deep Learning Framework for Cellular Senescence Detection from Protein Sequences
TILLCANN：一种用于大麻（Cannabis sativa）突变发现和作物改良的TILLING平台	Duarte-Delgado, D.	PDF	N/A	TILLCANN: A TILLING platform in Cannabis sativa for mutation discovery and crop improvement
# BioRxiv 2024-10-31 Papers

标题	作者	PDF链接	代码仓库	Title
猕猴意识访问的介尺度连接组模型	Klatzmann, U.	PDF	N/A	A MESOSCALE CONNECTOME-BASED MODEL OF CONSCIOUS ACCESS IN THE MACAQUE MONKEY
猪带绦虫幼虫阶段RT-qPCR相对表达分析中参考基因的验证	Castaneda, D.	PDF	N/A	Validation of Reference Genes for RT-qPCR Relative Expression Analysis in Pre-Adult Stages of Taenia solium
社会蜜蜂（Bombus impatiens）中的雌性生殖是由蜂王调控的。	Santos, P. K. F.	PDF	N/A	Gyne production is regulated by the brood in a social bee (Bombus impatiens)
LoxCode 体内克隆条形码技术解析了哺乳动物胚胎外胚层对胎儿器官的贡献	Weber, T. S.	PDF	N/A	LoxCode in vivo clonal barcoding resolves mammalian epiblast contribution to fetal organs
一种与Toll受体共同作用的神经营养因子调控多巴胺能环路中的结构可塑性	Sun, J.	PDF	N/A	A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit
药物抑制星形胶质细胞中的转谷氨酰胺酶2有助于促进神经支持性星形胶质细胞反应表型的表达，这与组蛋白乙酰化水平的增加相关。	Delgado, T.	PDF	N/A	Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation
复制应激诱导的ELF3上调促进了BRCA1缺陷型乳腺管腔祖细胞的肿瘤发生	Zhou, J.	PDF	N/A	Replication stress inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors
克隆性造血的人血浆蛋白质组特征	Yu, Z.	PDF	N/A	Human Plasma Proteomic Profile of Clonal Hematopoiesis
丘脑的 reuniens 核在睡眠期间促进海马与皮层之间的对话。	Basha, D.	PDF	N/A	The reuniens nucleus of the thalamus facilitates hippocampo-cortical dialogue during sleep
神经科学中的无监督对齐：介绍用于Gromov-Wasserstein最优传输的工具箱	Sasaki, M.	PDF	N/A	Unsupervised Alignment in Neuroscience: Introducing a Toolbox for Gromov-Wasserstein Optimal Transport
学习阶段恢复	Halpern, D.	PDF	N/A	Study-Phase Reinstatement
确保多模态单细胞数据的对角线整合，防止模糊映射	Zhou, H.	PDF	N/A	Securing diagonal integration of multimodal single-cell data against ambiguous mapping
人源化GM-CSF/IL-3增强人源化肝癌患者来源异种移植瘤中的肿瘤免疫浸润	Weinfurtner, K.	PDF	N/A	Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts
果蝇盐生种群中网状进化的跃变事件	Prediger, C.	PDF	N/A	Saltational episodes of reticulate evolution in the Drosophila saltans species group
无突触蛋白在保守的Nedd4 E3泛素连接酶途径中充当底物适配器，促进轴突跨中线生长。	Sullivan, K. G.	PDF	N/A	Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline
通过一个可组装的计算框架探索人类决策异常中的有限理性	Lu, Y.-L.	PDF	N/A	Exploring the bounded rationality in human decision anomalies through an assemblable computational framework
预期性平滑眼动与视觉运动概率成比例：目标速度和加速度的作用	Carneiro Morita, V.	PDF	N/A	Anticipatory smooth eye movements scale with the probability of visual motion: role of target speed and acceleration
RNPS1 在 PSAP 复合物中控制细胞周期内的周期性前体 mRNA 剪接	Fukumura, K.	PDF	N/A	RNPS1 in PSAP complex controls periodic pre-mRNA splicing over the cell cycle
甲虫幼虫释放的化学信号能够触发植物病原体的增殖，并可能诱导其毒力基因的表达。	Cambon, M. C.	PDF	N/A	Chemical cues from beetle larvae trigger proliferation and putative virulence gene expression of a plant pathogen
多尺度研究丘脑状态依赖性反应性	Overwiening, J.	PDF	N/A	A Multi-Scale Study of Thalamic State-Dependent Responsiveness
纤毛转录程序在精子发生过程中通过拮抗转录因子的调控	Wang, W.	PDF	N/A	Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors
p110α依赖的肝细胞信号传导对肝脏基因表达及其在代谢相关脂肪性肝病（MASLD）中的重塑至关重要。	Regnier, M.	PDF	N/A	p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD
酪胺修饰的透明质酸分子量对THP-1和外周血单核细胞衍生的巨噬细胞极化状态的影响	Wychowaniec, J. K.	PDF	N/A	Effect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages
用微藻替代饮食中的鱼油对金头鲷中肠细菌微生物群的影响	Katsoulis-Dimitriou, S.	PDF	N/A	The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota
在观看电影时将思维模式映射到大脑活动上	Wallace, R. S.	PDF	N/A	Mapping patterns of thought onto brain activity during movie-watching
利用单细胞转录组学识别可重复的转录调控因子共表达模式	Morin, A.	PDF	N/A	Identifying Reproducible Transcription Regulator Coexpression Patterns with Single Cell Transcriptomics
蜂群衰竭失调对蜜蜂生存产生负面影响：实验与元分析证据	Ostap-Chec, M.	PDF	N/A	Nosemosis negatively affects honeybee survival: experimental and meta-analytic evidence
根瘤菌效应蛋白NopT靶向豆科植物百脉根中的结瘤因子受体，以调控共生关系	Bao, H.	PDF	N/A	The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus
使用生成模型预测蛋白质折叠的绝对稳定性	Cagiada, M.	PDF	N/A	Predicting absolute protein folding stability using generative models
单细胞分析揭示了宫颈腺癌的肿瘤内异质性和免疫抑制微环境	Peng, Y.	PDF	N/A	Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma
MftG通过将霉菌素氧化与呼吸作用相连接，对分枝杆菌的乙醇代谢至关重要。	Graca, A. P.	PDF	N/A	MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
希瓦氏菌可能是堆肥蚯蚓（Eisenia fetida）肠道土壤中多不饱和脂肪酸的生产者。	Wittlinger, J.-P.	PDF	N/A	Shewanella is a putative producer of polyunsaturated fatty acids in the gut soil of the composting earthworm Eisenia fetida
捕食者-猎物幂律的自上而下起源的一般机制	Mazzarisi, O.	PDF	N/A	General mechanisms for a top-down origin of the predator-prey power law
共享通路特异性网络机制：多巴胺与深部脑刺激治疗帕金森病的研究	Binns, T. S.	PDF	N/A	Shared pathway-specific network mechanisms of dopamine and deep brain stimulation for the treatment of Parkinson's disease
诱导乙型肝炎核心蛋白聚集，靶向非常规结合位点	Khayenko, V.	PDF	N/A	Induction of Hepatitis B Core Protein Aggregation Targeting an Unconventional Binding Site
软骨细胞中的eQTLs（表达数量性状位点）、染色质可及性及三维染色质结构为骨关节炎风险提供了机制性见解。	Kramer, N. E.	PDF	N/A	Response eQTLs, chromatin accessibility, and 3D chromatin structure in chondrocytes provide mechanistic insight into osteoarthritis risk
产乙酸菌对H2的消耗遵循一级动力学。	Munoz, L.	PDF	N/A	H2 consumption by acetogenic bacteria follows first-order kinetics
胸主动脉三维几何结构	Beeche, C.	PDF	N/A	Thoracic Aortic Three-Dimensional Geometry
对超过30,000种化合物进行高通量筛选，以寻找对抗胃肠道线虫寄生虫的抗蠕虫药物	Elfawal, M. A.	PDF	N/A	High-throughput screening of more than 30,000 compounds for anthelmintics against gastrointestinal nematode parasites
对视觉特征的敏感性在无意视盲中	Nartker, M.	PDF	N/A	Sensitivity to visual features in inattentional blindness
单细胞转录组学揭示了21三体和GATA1s对造血的个体及协同效应	Takasaki, K.	PDF	N/A	Single-cell transcriptomics reveal individual and synergistic effects of Trisomy 21 and GATA1s on hematopoiesis
Kermut: 蛋白质变体效应的复合核回归	Groth, P. M.	PDF	N/A	Kermut: Composite kernel regression for protein variant effects
不太格子化：内部表征的循环神经网络路径整合了不止一个代理	Redman, W.	PDF	N/A	Not so griddy: Internal representations of RNNs path integrating more than one agent
在秀丽隐杆线虫中，对铜绿假单胞菌的跨代反应并不显著	Gainey, D. P.	PDF	N/A	Reported transgenerational responses to Pseudomonas aeruginosa in C. elegans are not robust
解耦个体宿主反应与免疫细胞衔接子细胞毒性效力	Gonzalez Gutierrez, C.	PDF	N/A	Decoupling individual host response and immune cell engager cytotoxic potency
对巴布亚新几内亚丹皮尔群岛弗格森岛的鸟类学调查揭示了新的岛屿记录和值得注意的自然历史观察结果。	Boersma, J.	PDF	N/A	An ornithological survey of Fergusson Island, D'Entrecasteaux Archipelago, Papua New Guinea, reveals new island records and noteworthy natural history observations
用于条件脑模板的深度微分同胚网络	Whitbread, L.	PDF	N/A	Deep-diffeomorphic networks for conditional brain templates
平滑肌细胞中RNA编辑酶ADAR1的表达调控动脉粥样硬化中RNA传感器MDA5的激活	Weldy, C. S.	PDF	N/A	Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of RNA sensor MDA5 in atherosclerosis
氮化硅通过激活线粒体氧化磷酸化和新生血管化促进骨传导	Gonzales, W. D.	PDF	N/A	Silicon Nitride Induces Osteoconduction Via Activated Mitochondrial Oxidative Phosphorylation and Neovascularization
嗅觉皮层输出招募并塑造了不同的大脑广泛时空网络	Ma, T.	PDF	N/A	Olfactory cortical outputs recruit and shape distinct brain-wide spatiotemporal networks
使用松露犬有助于了解美国俄勒冈州西部Genea（Pyronemataceae）的生态及其丰富的发生情况。	Dawson, H. R.	PDF	N/A	Use of a truffle dog provides insight into the ecology and abundant occurrence of Genea (Pyronemataceae) in western Oregon, U.S.A.
利用扩展拼接光片显微镜对无性扁形虫的神经元异速生长和神经肌肉投射进行三维重建	Lu, J.	PDF	N/A	3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy
尾状核的集成单细胞多组学分析揭示了酒精使用障碍的关键机制	Green, N.	PDF	N/A	Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder
从混乱的化学到生态学：前生物学上合理的化学系统中的自催化与遗传性	Sokolskyi, T.	PDF	N/A	From messy chemistry to ecology: autocatalysis and heritability in prebiotically plausible chemical systems
BCL2L13 影响自噬和鞘脂代谢，但不影响胶质母细胞瘤中的替莫唑胺耐药性	Clark, C.	PDF	N/A	BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma
铁状态和乙烯信号在应对大豆同时遭受铁缺乏和干旱胁迫的抗逆性中的作用	Hasan, M. R.	PDF	N/A	Role of iron status and ethylene signaling in stress resilience of soybean exposed to combined iron deficiency and drought
慢性弓形虫感染过程中淀粉样颗粒积累的动力学与囊内缓殖子复制相关。	Tripathi, A.	PDF	N/A	Dynamics of amylopectin granule accumulation during the course of the chronic Toxoplasma infection is linked to intra-cyst bradyzoite replication.
Kontextual：重新构建空间组学数据分析揭示了图像间一致的细胞关系	Ameen, F.	PDF	N/A	Kontextual: Reframing analysis of spatial omics data reveals consistent cell relationships across images
人类小脑中浦肯野细胞树突的非等比扩张和增强的区室化	Busch, S. E.	PDF	N/A	Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum
应激诱导小蛋白的翻译组学分析揭示了不同信号系统之间出乎意料的联系	Vellappan, S.	PDF	N/A	Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems
番茄半胱氨酸蛋白酶抑制剂SlCYS8作为马铃薯抗旱性和块茎产量的触发因子	Dorval, M.	PDF	N/A	Tomato cystatin SlCYS8 as a trigger of drought tolerance and tuber yield in potato
少样本一致性神经解码（FALCON）基准算法	Karpowicz, B. M.	PDF	N/A	Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark
靶向与帕金森病相关的LRRK2的II型激酶抑制剂	Raig, N. D.	PDF	N/A	Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
TIRTL-seq：深度、定量且经济实惠的配对TCR受体组测序	Pogorelyy, M. V.	PDF	N/A	TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing
终身健身益处包括繁殖地点的忠诚度和近亲繁殖成本低，这使得近亲繁殖容忍度在一种鸟类合作繁殖者中得以实现。	Shah, S.	PDF	N/A	Lifetime fitness benefits of breeding site fidelity and low costs of inbreeding permit inbreeding tolerance in an avian cooperative breeder
寄生传播时间的选择塑造了宿主冈比亚按蚊的转录反应，并提示了免疫逃避机制	Silva, L. M.	PDF	N/A	Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion
Tau P301S转基因小鼠表现出类似于进行性核上性麻痹的步态和眼球运动障碍。	Creed, R. B.	PDF	N/A	Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy
巨核细胞组装了一个三维的细胞外基质笼，这个笼子控制着它们的成熟和锚定到血管壁的微环境。	Masson, C.	PDF	N/A	Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
便携式现场DNA测序用于快速检测病原体及抗菌药物耐药性：概念验证研究	Pillay, S.	PDF	N/A	Portable In-Field DNA Sequencing for Rapid Detection of Pathogens and Antimicrobial Resistance: A Proof-of-Concept Study
Danicamtiv通过减少肌球蛋白的工作冲程，但通过激活细肌丝来增强收缩。	Scott, B.	PDF	N/A	Danicamtiv reduces myosin's working stroke but enhances contraction by activating the thin filament
在来自狗衰老项目的多样化犬类群体中，转座子的DNA甲基化模式揭示了衰老差异	Mariner, B. L.	PDF	N/A	DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project
活性氧解毒作用有助于脓肿分枝杆菌对抗生素的存活	Bates, N. A.	PDF	N/A	Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival
在癌症的网络基础分层分析中整合遗传和基因表达数据	Liou, K.	PDF	N/A	Integrating genetic and gene expression data in network-based stratification analysis of cancers
涉及lncRNA MB3及驱动基因MYC和OTX2的电路通过HMGN5调控TGF-β通路，抑制了3型髓母细胞瘤中的细胞凋亡。	Grandioso, A.	PDF	N/A	A circuit involving the lncRNA MB3 and the driver genes MYC and OTX2 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5
象牙喙啄木鸟与蓝松鸦在频谱图层面的比较显示出差异	Williams, J. D.	PDF	N/A	Ivory-billed Woodpecker and Blue Jay kent comparisons at spectrogram level reveal differences
邻近标记揭示了人类线粒体导入受体蛋白TOMM20和TOMM70的不同相互作用伙伴	Akram, S.	PDF	N/A	Proximity labeling reveals differential interaction partners of the human mitochondrial import receptor proteins TOMM20 and TOMM70
表达人α1,4-半乳糖基转移酶的B4GALT5缺陷CHO-Lec2细胞：用于研究志贺毒素受体的糖工程细胞模型	Mikolajczyk, K.	PDF	N/A	B4GALT5-deficient CHO-Lec2 cells expressing human alpha1,4-galactosyltransferase: a glycoengineered cell model for studying Shiga toxin receptors
解开应力纤维和未成束肌动蛋白网络对细胞形状响应的皮质张力各向异性贡献的纠缠	Fage, F.	PDF	N/A	Disentangling the contributions of stress fibres and the unbundled actin meshwork to the anisotropy of cortical tension in response to cell shape
缓症链球菌群糖脂的生物合成及其在生理和抗生素敏感性中的作用	Wei, Y.	PDF	N/A	Biosynthesis of mitis group streptococcal glycolipids and their roles in physiology and antibiotic susceptibility
使用Opal-TSA放大技术进行三维多重免疫组织化学，以增强肺结核病变成像	Lata, S.	PDF	N/A	3D Multiplexed Immunohistochemistry Using Opal-TSA Amplification for Enhanced Imaging of Pulmonary TB Lesions
对古代信号通路中的自然变异进行大规模并行实验分析，揭示了净化选择和局部适应的存在。	Aguilar-Rodriguez, J.	PDF	N/A	Massively parallel experimental interrogation of natural variants in ancient signaling pathways reveals both purifying selection and local adaptation
CFC-seq：全长加帽RNA的鉴定揭示增强子来源的转录	Yip, C. W.	PDF	N/A	CFC-seq: identification of full-length capped RNAs unveil enhancer-derived transcription
一个大型复杂系统会形成图灵图案吗？	Piskovsky, V.	PDF	N/A	Will a large complex system form Turing patterns?
1.6埃分辨率下的光系统II相关锰结合TPM结构域蛋白的晶体结构	Vidal-Meireles, A.	PDF	N/A	Crystal structure of a Photosystem II-related, Manganese-binding, TPM-domain protein at a 1.6 A resolution
工作记忆连接认知、情感与大脑结构：基于人类连接组计划-青年成人数据的多层网络分析	Firman-Sadler, L.	PDF	N/A	Working Memory Bridges Cognition, Emotion, and Brain Structure: A Multilayer Network Analysis of the Human Connectome Project-Young Adult
人脑内嗅皮层中用于序列记忆的分层坐标系统。	Shpektor, A.	PDF	N/A	A hierarchical coordinate system for sequence memory in human entorhinal cortex.
癌细胞衍生的cGAMP限制了肿瘤相关CD8+ T细胞的活性	Herbst, M.	PDF	N/A	Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells
一种VersaTile方法用于重新编程R2型tailocin对不同血清型的埃希氏大肠杆菌和肺炎克雷伯菌的特异性	Dams, D.	PDF	N/A	A VersaTile approach to reprogram the specificity of the R2-type tailocin towards different serotypes of Escherichia coli and Klebsiella pneumoniae
利用改良的群体分离分析法鉴定出酿酒酵母对铜抗性的上位性和隐性数量性状位点	Buzby, C.	PDF	N/A	Epistasis and cryptic QTL identified using modified bulk segregant analysis of copper resistance in budding yeast
通过改良的批量分离分析法鉴定出酿酒酵母铜抗性的上位性和隐秘数量性状位点	Buzby, C.	PDF	N/A	Epistasis and cryptic QTL identified using modified bulk segregant analysis of copper resistance in budding yeast
Bax抑制肽的计算设计	Vlaar, T.	PDF	N/A	Computational design of Bax-inhibiting peptides
机械拉伸诱导细胞集体排列	Shi, X.	PDF	N/A	Mechanical stretch induced collective cell alignment
GESIAP3.0：基于传感器的图像分析程序，用于体内传输可视化	Zhu, R. E.	PDF	N/A	GESIAP3.0: Sensor-based Image Analysis Program for Transmission Visualization In Vivo
神经TD：一种基于时频的多模态学习方法，用于分析神经活动中的时间延迟	Huang, X.	PDF	N/A	NeuroTD: A Time-Frequency Based Multimodal Learning Approach to Analyze Time Delays in Neural Activities
飞翔还是不飞翔，这是个问题：一种用于质谱中肽段可检测性预测的深度学习模型	Abdul-Khalek, N.	PDF	N/A	To fly, or not to fly, that is the question: A deep learning model for peptide detectability prediction in mass spectrometry
基于强化学习的基因组数据共享信标动态隐私保护方法	Poorghaffar Aghdam, M.	PDF	N/A	A Reinforcement Learning-based Approach for Dynamic Privacy Protection in Genomic Data Sharing Beacons
TIPP3 和 TIPP3-fast：改进的宏基因组丰度分析	Shen, C.	PDF	N/A	TIPP3 and TIPP3-fast: Improved Abundance Profiling in Metagenomics
脂筏稳定性和蛋白质-筏分区的小分子调节剂	Stefanski, K. M.	PDF	N/A	Small-molecule modulators of lipid raft stability and protein-raft partitioning
GPCRVS - 基于人工智能的GPCR虚拟筛选决策支持系统	Latek, D.	PDF	N/A	GPCRVS - AI-driven decision support system for GPCR virtual screening
应用2H2O量化年轻训练有素和未经训练的男性和女性的红细胞蛋白合成率	Kontro, H.	PDF	N/A	Application of 2H2O to quantify red blood cell protein synthesis rates in young trained and untrained males and females
使用非线性混合效应模型对钙-钙调蛋白动力学方案进行拟合和比较，以共同数据集为依据	Linkevicius, D.	PDF	N/A	Fitting and comparison of calcium-calmodulin kinetic schemes to a common data set using non-linear mixed effects modelling
空间转录组学揭示了生精上皮周期的时间结构及精确的Sertoli-生殖细胞同步化	Chakravorty, A.	PDF	N/A	Spatial Transcriptomics Reveals the Temporal Architecture of the Seminiferous Epithelial Cycle and Precise Sertoli-Germ Synchronization
在单细胞分辨率下绘制肿瘤内髓系细胞与T细胞的相互作用图谱，揭示了克服检查点抑制剂耐药性的靶点	Bridges, K.	PDF	N/A	Mapping intratumoral myeloid-T cell interactomes at single-cell resolution reveals targets for overcoming checkpoint inhibitor resistance
在发育过程中，突触基因表达通过保守的染色质调控因子进行协调。	Kentro, J. A.	PDF	N/A	Synaptic gene expression is coordinated across development by conserved chromatin regulators
一项关于社区为基础的狂犬病疫苗接种策略有效性的随机对照试验	Lankester, F.	PDF	N/A	A randomized controlled trial of the effectiveness of a community-based rabies vaccination strategy
perR对艰难梭菌630Δerm中氧气敏感性、基因表达及小鼠感染的影响	Gregory, A. L.	PDF	N/A	Impacts of perR on oxygen sensitivity, gene expression, and murine infection in Clostridioides difficile 630Δerm
局部异质性土壤病毒和原核生物对规定的烧除的响应与混合针叶林中斑块状的烧除严重程度相对应	Geonczy, S.	PDF	N/A	Locally heterogeneous soil viral and prokaryotic responses to prescribed burn correspond with patchy burn severity in a mixed conifer forest
人类N-糖基化途径中的宏观进化模式对比	Kifer, D.	PDF	N/A	Contrasting macroevolutionary patterns in the human N-glycosylation pathway
宿主扩散与寄生物毒力在复杂景观中的协同进化。	Deshpande, J. N.	PDF	N/A	Co-evolution of host dispersal and parasite virulence in complex landscapes.
Ana1的N端和C端部分的相互作用允许中心粒复制但不允许延长	Nagy, A.	PDF	N/A	Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation
亚洲黄蜂（Vespa velutina nigrithorax，du Buysson 1905）在斯洛伐克的最东部分布：迫切需要加强检测和跨区域监测	Balazs, K.	PDF	N/A	Easternmost distribution of Asian hornet (Vespa velutina nigrithorax, du Buysson 1905) in Slovakia: Urgent need for advanced detection and interregional monitoring
CDC45突变对DNA复制和基因组稳定性的影响	Denkiewicz-Kruk, M.	PDF	N/A	The effects of CDC45 mutations on DNA replication and genome stability
GBRAP：一个全面的数据库和工具，用于探索所有生命领域的基因组多样性	Yaddehige, S. K.	PDF	N/A	GBRAP: A Comprehensive Database and Tool for Exploring Genomic Diversity Across All Domains of Life
威瑟姆森林中欧洲栎（Quercus robur）的遗传多样性和群体结构	Hung, T. H.	PDF	N/A	Genetic diversity and population structure of pedunculate oaks (Quercus robur) in Wytham Woods
为雄性山地大猩猩提供了一个接近端粒到端粒的相位参考组装	Nelson, D. R.	PDF	N/A	A near telomere-to-telomere phased reference assembly for the male mountain gorilla
提高大型流行病学研究中体细胞突变分析的准确性：解决无匹配正常样本病例的问题	Arora, A.	PDF	N/A	Improving Accuracy of Somatic Mutation Profiling in Large Epidemiologic Studies: Addressing Cases without Matched Normal Samples
利用蛋白质大型语言模型设计新型脱卤酶	Garcia, L. N.	PDF	N/A	Design of Novel Dehalogenases using Protein Large Language Models
UnCOT-AD：无配对跨组学翻译实现阿尔茨海默病预测的多组学整合	Abir, A. R.	PDF	N/A	UnCOT-AD: Unpaired Cross-Omics Translation Enables Multi-Omics Integration for Alzheimer's Disease Prediction
基于扩散的人工基因组及其在本地血统推断中的实用性	Szatkownik, A.	PDF	N/A	Diffusion-based artificial genomes and their usefulness for local ancestry inference
使用分子荧光寿命传感器监测单个DNA折纸纳米结构的涂层	Scheckenbach, M.	PDF	N/A	Monitoring the Coating of Single DNA Origami Nanostructures with a Molecular Fluorescence Lifetime Sensor
2013-2016年疫情期间埃博拉病毒糖蛋白A82V变异体膜融合活性增强的分子基础：来自模拟与实验的见解	Durham, N. D.	PDF	N/A	Molecular basis for the increased membrane fusion activity of the Ebola virus glycoprotein A82V variant from the 2013-2016 epidemic: insights from simulations and experiments
有机和无机污染物及其混合物对发育暴露的斑马鱼代谢健康和基因表达的影响	Berube, R.	PDF	N/A	Effects of organic and inorganic contaminants and their mixtures on metabolic health and gene expression in developmentally exposed zebrafish
基于片段的小分子抑制剂开发，靶向结核分枝杆菌胆固醇代谢	Kavanagh, M. E.	PDF	N/A	Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism
机器学习模型揭示了与植物生物钟相关的环境和遗传因素	Reynolds, C.	PDF	N/A	Machine learning models reveal environmental and genetic factors associated with the plant circadian clock
机器学习方法在干燥综合征单细胞转录组分析中的应用揭示了B细胞和T淋巴细胞激活状态的改变	McDermott, M.	PDF	N/A	Machine Learning Approach to Single Cell Transcriptomic Analysis of Sjogren's Disease Reveals Altered Activation States of B and T Lymphocytes
领土行为作为非社会性哺乳动物中社会微生物传播的途径	Petrullo, L.	PDF	N/A	Territorial behavior as a route of social microbial transmission in an asocial mammal
LCL：用于谱系条形码单细胞RNA测序数据的对比学习	Yang, S. J.	PDF	N/A	LCL: Contrastive Learning for Lineage Barcoded scRNA-seq Data
通过本地祖先推断在gnomAD中改进的等位基因频率	Atkinson, E. G.	PDF	N/A	Improved Allele Frequencies in gnomAD through Local Ancestry Inference
高孔隙率颗粒状水凝胶，通过静电纺丝水凝胶纤维增强，实现长期稳定性	Whitewolf, J.	PDF	N/A	Highly porous granular hydrogels reinforced by electrospun hydrogel fibers for long-term stability
运输相关因素对人脑皮质神经元内在及突触特性的影响：一项比较研究	Qi, G.	PDF	N/A	Transport-Related Effects on Intrinsic and Synaptic Properties of Human Cortical Neurons: A Comparative Study
视网膜小胶质细胞来源的S100A9在西方饮食喂养的Ossabaw猪视网膜中激发NLRP3炎症小体	Lim, R. R.	PDF	N/A	Retinal microglia-derived S100A9 incite NLRP3 inflammasome in a Western diet fed Ossabaw pig retina
结节性硬化症皮质结节的单细胞分析显示分子结构保存及代谢的大规模重构	Sorensen, F. N. F.	PDF	N/A	Single-cell profiling of cortical tubers in tuberous sclerosis complex shows molecular structure preservation and massive reorganization of metabolism
RATS：使用低失真对齐切线空间的无监督流形学习	Kohli, D.	PDF	N/A	RATS: Unsupervised manifold learning using low-distortion alignment of tangent spaces
瞳孔扩张提供了一个预测误差的时间窗口	Colizoli, O.	PDF	N/A	Pupil dilation offers a time-window on prediction error
在向内凹陷的杆状突触中，几何扭曲减缓了谷氨酸的扩散并塑造了突触反应：来自解剖学上真实的蒙特卡罗模拟的见解	Thoreson, W. B.	PDF	N/A	Geometric tortuosity at invaginating rod synapses slows glutamate diffusion and shapes synaptic responses: insights from anatomically realistic Monte Carlo simulations
缺乏赖氨酸和磨损的果蝇Act与dSarm并行作用，在dNmnat耗尽后驱动神经退行性变	Avetisyan, A.	PDF	N/A	Drosophila with-no-lysine and frayed Act in Parallel to dSarm to Drive Neurodegeneration Following dNmnat Depletion
次级运动皮层追踪决策价值，并在非指令性选择过程中支持行为灵活性	Augusto, E.	PDF	N/A	Secondary motor cortex tracks decision value and supports behavioral flexibility during non-instructed choice
上丘眼跳前场电位主要受视觉感官对上视野的偏好影响。	Hafed, Z. M.	PDF	N/A	Superior colliculus peri-saccadic field potentials are dominated by a visual sensory preference for the upper visual field
星形胶质细胞转录组分析发现，糖基化蛋白5下调是阿尔茨海默病模型中突触功能障碍的一个因素。	Salas, I. H.	PDF	N/A	Astrocyte transcriptomic analysis identifies glypican 5 downregulation as a contributor to synaptic dysfunction in Alzheimer disease models
在老鼠视网膜中，杆状细胞的输入信号仅通过杆-锥耦合方式到达水平细胞的细胞体。	Thoreson, W.	PDF	N/A	Rod inputs arrive at horizontal cell somas in mouse retina solely via rod-cone coupling
单个神经元EI平衡的短期可塑性可以检测模式转换	Asopa, A.	PDF	N/A	Short-term plasticity of EI balance at single neurons can detect pattern transitions
WTools：一个基于MATLAB的时间-频率分析工具箱	Ferrari, A.	PDF	N/A	WTools: a MATLAB-based toolbox for time-frequency analysis
抽象规则泛化以构成新意义时，会招募前顶叶控制网络	Zheng, X. Y.	PDF	N/A	Abstract rule generalization for composing novel meaning recruits the frontoparietal control network
用于声源分离的基于双耳时间差的哺乳动物下丘模型	Leibold, C.	PDF	N/A	A mammalian inferior colliculus model for sound source separation using interaural time differences
任务执行期间结构-功能脑网络耦合揭示与智力相关的沟通策略	Popp, J. L.	PDF	N/A	Structural-Functional Brain Network Coupling During Task Performance Reveals Intelligence-Relevant Communication Strategies
不同地区经济变量的独特表征及前额叶皮层的预测	Majumdar, A.	PDF	N/A	Distinct representations of economic variables across regions and projections of the frontal cortex
多尺度激发-抑制平衡动力学：整合代谢物动力学与时变执行网络	Saviola, F.	PDF	N/A	Multiscale excitation-inhibition balance dynamics: integrating metabolite kinetics with time-varying executive networks
观察几何学驱动着对物体运动和深度的灵活感知。	Xu, Z.-X.	PDF	N/A	Viewing geometry drives flexible perception of object motion and depth
IL-17A改变人类皮质发育在母体免疫激活的三维体外模型中	Assir, M. Z. K.	PDF	N/A	IL-17A Alters Human Cortical Development in a 3D Ex Vivo Model of Maternal Immune Activation
顺序转录程序支撑静息海马干细胞的激活。	Rigo, P.	PDF	N/A	Sequential transcriptional programs underpin activation of quiescent hippocampal stem cells.
细菌对氧化应激因子的改变影响流感病毒A型的环境稳定性	Williams, M. R.	PDF	N/A	Bacterial alteration of redox stressors impact environmental stability of Influenza A virus
时空转录组分析揭示了发育过程中分子梯度模式以及沿耳蜗轴的音调组织。	Yan, M.	PDF	N/A	Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along cochlear axis
非甾体抗炎药（NSAID）介导的环氧合酶抑制作用破坏了蝾螈胚胎中外胚层衍生物的形成。	Marshall, E. J.	PDF	N/A	NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos
发育中的人类生殖道在单细胞分辨率下的时空图谱	Lorenzi, V.	PDF	N/A	Spatiotemporal map of the developing human reproductive tract at single-cell resolution
Tit wit：城市化梯度上认知变异的环境和遗传驱动因素	Thompson, M. J.	PDF	N/A	Tit wit: environmental and genetic drivers of cognitive variation along an urbanization gradient
一种新型人类TBCK-神经元细胞模型导致严重的神经退行性变，并通过抑制线粒体分裂得到部分挽救	Angireddy, R.	PDF	N/A	A Novel Human TBCK- Neuronal Cell Model Results in Severe Neurodegeneration and Partial Rescue with Mitochondrial Fission Inhibition
β频带去同步化的因果作用：个性化高清晰度经颅交流电刺激改善双手运动控制	Van Hoornweder, S.	PDF	N/A	The Causal Role Of Beta Band Desynchronization: Individualized High-Definition Transcranial Alternating Current Stimulation Improves Bimanual Motor Control
语言和情感韵律：一个统一视角。皮质韵律组织的系统综述与ALE元分析	Themistocleous, C.	PDF	N/A	Linguistic and Affective Prosody. A Unifying Perspective:A Systematic Review and ALE Meta-Analysis of the Cortical Organization of Prosody
眼动系统微刺激下稳健目标选择背后的神经机制	Rakhshan, M.	PDF	N/A	Neural mechanisms underlying robust target selection in response to microstimulation of the oculomotor system
BrainACTIV：利用基于扩散的图像操作识别驱动皮层选择性的视觉语义属性	Garcia Cerdas, D.	PDF	N/A	BrainACTIV: Identifying visuo-semantic properties driving cortical selectivity using diffusion-based image manipulation
使用两步非局部主成分分析方法去噪复数扩散磁共振图像	Ye, X.	PDF	N/A	Denoising complex-valued diffusion MR images using a two-step non-local principal component analysis approach
心理旋转是对视觉化倾向的一种较弱的衡量方式。	Arnold, D. H.	PDF	N/A	Mental Rotation is a weak measure of the propensity to visualise.
骨桥蛋白在M2和M4型内在光敏视网膜神经节细胞中的表达	Lindner, M.	PDF	N/A	Expression of Osteopontin in M2 and M4 intrinsically photosensitive retinal ganglion cells
神经化小鼠嗅觉类器官的协议	Ozgun, A.	PDF	N/A	A Protocol for Neuralized Murine Olfactory Organoids
使用智能手机对手部和脚部运动技能进行15秒评估	Takagi, A.	PDF	N/A	15 second assessment of hand and foot motor skill using a smartphone
向无名质投射的食欲素能神经元介导觉醒和镇痛。	Xiang, X.	PDF	N/A	Orexinergic projections to substantia innominata mediate arousal and analgesia
野生型超氧化物歧化酶1的成熟受损与帕金森病脑部神经退行性变及一种新型小鼠模型相关	Abdeen, A. H.	PDF	N/A	Impaired maturation of wild-type superoxide dismutase 1 associated with neurodegeneration in Parkinson disease brain and a novel murine model
使用深度学习方法进行基于模型的深脑刺激控制	Saradhi, S.	PDF	N/A	Using a Deep Learning Approach for Model-based Control of Deep Brain Stimulation
小鼠睡眠剥夺：超越慢波反弹的观察	Magyar, T. Z.	PDF	N/A	Sleep Deprivation in Mice: Looking Beyond the Slow Wave Rebound
持续的捕食者气味应激源通过前边缘皮层中的GABA-A受体适应增强了雄性大鼠对酒精的内感受敏感性，但在雌性大鼠中未观察到此效应。	Tyler, R. E.	PDF	N/A	The persistent effects of predator odor stressor enhance interoceptive sensitivity to alcohol through GABA-A receptor adaptations in the prelimbic cortex in male, but not female rats
PFOS对甲状腺激素驱动的神经发育和非洲爪蟾蝌蚪类似变态变化的剂量依赖性影响	Zirkle, K.	PDF	N/A	Dose-Dependent Effects of PFOS on Thyroid Hormone-Driven Neurodevelopment and Metamorphic-like change in Xenopus laevis larvae
内侧隔区表达小清蛋白的抑制性神经元在Dravet综合征小鼠模型中受损	Zhu, L.	PDF	N/A	Medial septum parvalbumin-expressing inhibitory neurons are impaired in a mouse model of Dravet Syndrome
不同的血清素能神经元调节对蔗糖的食欲和对蛋白质的饥饿感。	Dorn, K.	PDF	N/A	Different serotonergic neurons regulate appetite for sucrose and hunger for proteins
阿尔茨海默病中性与区域特异性的自噬与线粒体自噬紊乱：将细胞功能障碍与认知衰退相联系	Adlimoghaddam, A.	PDF	N/A	Sex and Region-Specific Disruption of Autophagy and Mitophagy in Alzheimer's Disease: Linking Cellular Dysfunction to Cognitive Decline
基于细胞类型特异性微电路的猕猴与小鼠皮质层次比较	Glatigny, M.	PDF	N/A	Comparison of the cortical hierarchy between macaque monkeys and mice based on cell-type specific microcircuits
使用几何特征模态对大脑皮层图谱的半球不对称性进行多尺度定量分析	Milloz, A.	PDF	N/A	Multiscale Quantification of Hemispheric Asymmetry in Cortical Maps Using Geometric Eigenmodes
脂质失衡影响神经元树突生长和维持在人神经酰胺合酶疾病模型中	Ziegler, A. B.	PDF	N/A	Lipid Disbalance Affects Neuronal Dendrite Growth and Maintenance in a Human Ceramide Synthase Disease Model
公共物品游戏中合作行为中对共同玩家身份和声誉处理的神经关联	Sampaio, W. M.	PDF	N/A	Neural correlates of co-players' identity and reputation processing on cooperation in the public goods game
STRIPAK复合体在施万细胞的径向排序和层粘连蛋白受体表达中是必需的。	Weaver, M. R.	PDF	N/A	The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells
通过源分离实现宽带脑网络估计（BROAD-NESS）	Bonetti, L.	PDF	N/A	BROADband brain Network Estimation via Source Separation (BROAD-NESS)
饲养期间的高温会降低黄鳍鲈幼体的游泳能力，并扰乱其新陈代谢。	Easwaramoorthy, M.	PDF	N/A	Elevated temperature during rearing diminishes swimming and disturbs the metabolism of yellow perch larvae
一种用于全基因组昼夜节律生物标志物检测的贝叶斯框架	Ding, H.	PDF	N/A	A Bayesian Framework for Genome-wide Circadian Rhythmicity Biomarker Detection
氧化应激对腺苷A2a受体结构、活性和信号传导的影响	Company, I.	PDF	N/A	The effect of oxidative stress on the Adenosine A2a Receptor structure, activity and signalling
一种全面且稳健的多重DIA工作流程揭示了与顺铂耐药相关的蛋白质周转调控	Salovska, B.	PDF	N/A	A Comprehensive and Robust Multiplex-DIA Workflow Profiles Protein Turnover Regulations Associated with Cisplatin Resistance
抗原印迹在仓鼠COVID-19模型中对SARS-CoV-2新变种的体液反应中占主导地位	Degryse, J.	PDF	N/A	Antigenic imprinting dominates humoral responses to new variants of SARS-CoV-2 in a hamster model of COVID-19
疫苗诱导的T细胞反应的质量通过多克隆性和高（而非最高）抗原受体亲和力来体现。	Kocher, K.	PDF	N/A	Quality of vaccination-induced T cell responses is conveyed by polyclonality and high, but not maximum, antigen receptor avidity
噬菌体编码的小RNA劫持宿主的复制机制，以支持噬菌体的裂解周期。	Silverman, A.	PDF	N/A	Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle
微生物对宿主饮食的转录反应维持了美洲大蠊肠道微生物群的稳态	DePoy, A. N.	PDF	N/A	Microbial transcriptional responses to host diet maintain gut microbiome homeostasis in the American cockroach
在Oz病毒（Thogotovirus属）的基因组中，RNA合成的片段特异性启动子活性	Akter, L.	PDF	N/A	Segment-specific promoter activity for RNA synthesis in the genome of Oz virus, genus Thogotovirus
非志贺毒素性聚集性肠致病性大肠杆菌O104:H4暴发菌株毒力质粒的遗传和表型分析	Whelan, R.	PDF	N/A	Genetic and phenotypic analysis of the virulence plasmid of a non-Shigatoxigenic enteroaggregative Escherichia coli O104:H4 outbreak strain
全基因组分析金黄色葡萄球菌在牛奶中生长时的适应性决定因素	Marli, M. T.	PDF	N/A	Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk
在新发现的深海冷泉中，五年的微生物演替、群落构建与适应	Liang, Q.	PDF	N/A	Microbial succession, community assembly and adaptation over five years in a newly discovered deep-sea cold seep
细菌核糖体中药物结合位点的进化分歧	Ekemezie, C. L.	PDF	N/A	Evolutionary divergence of drug-binding sites in bacterial ribosomes
流感A病毒H7纳米抗体识别血凝素头部的保守免疫优势表位，并赋予异源亚型保护作用	Chen, Z.-S.	PDF	N/A	Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection
疏水性尾部使胞外伴侣蛋白集群蛋白具有多种功能	Yuste-Checa, P.	PDF	N/A	Hydrophobic tails enable diverse functions of the extracellular chaperone clusterin
线粒体靶向肽治疗药物elamipretide在衰老过程中改善心脏和骨骼肌功能，同时未检测到组织表观遗传或转录组年龄的变化。	Mitchell, W.	PDF	N/A	The mitochondrial-targeted peptide therapeutic elamipretide improves cardiac and skeletal muscle function during aging without detectable changes in tissue epigenetic or transcriptomic age
棘阿米巴卡氏虫中人工转基因的命运	Colp, M. J.	PDF	N/A	The fate of artificial transgenes in Acanthamoeba castellanii
对莱茵衣藻（Chlamydomonas reinhardtii）叶绿体横穿类囊体的蛋白质组学分析揭示了新的组分	Franklin, E.	PDF	N/A	Proteomic analysis of the pyrenoid-traversing membranes of Chlamydomonas reinhardtii reveals novel components
PAM-flexible腺嘌呤碱基编辑在携带东亚创始人突变的人源化MPZL2小鼠模型中拯救了听力损失	Shu, Y.	PDF	N/A	PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation
APOBEC3A而非APOBEC3B驱动了人类胃上皮细胞中的脱氨酶突变。	An, Y.	PDF	N/A	APOBEC3A, not APOBEC3B, drives deaminase mutagenesis in human gastric epithelium
基于地标的基因组差异估计	Mohan, A. V.	PDF	N/A	Landmark-based estimates of genomic disparity
一个设计的Zn2+传感器结构域将结合信息传递给跨膜组氨酸激酶。	Hatstat, A. K.	PDF	N/A	A designed Zn2+ sensor domain transmits binding information to transmembrane histidine kinases
开发一种用于在聚球藻PCC 6803中靶向基因上调的CRISPR激活系统	Bourgade, B.	PDF	N/A	Development of a CRISPR activation system for targeted gene upregulation in Synechocystis sp. PCC 6803
在嗜热菌Parageobacillus thermoglucosidasius中合成甲基营养的RuMP循环的觉醒。	Paredes-Barrada, M.	PDF	N/A	Awakening of the RuMP cycle for synthetic methylotrophy in the thermophile Parageobacillus thermoglucosidasius.
糖蛋白K8.1对卡波西肉瘤相关疱疹病毒（KSHV）在狨猴感染模型中的肝脏和骨髓趋向性至关重要	Hennig, C. S.	PDF	N/A	Glycoprotein K8.1 is Critical for Liver and Bone Marrow Tropism of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) in the Marmoset Infection Model
沙眼衣原体TmeA通过N-WASP与TOCA-1的相互作用促进基座形成	McCullough, A.	PDF	N/A	Chlamydia trachomatis TmeA promotes pedestal formation through N-WASP and TOCA-1 interactions
宿主PIK3C3通过空泡形成促进福氏志贺氏菌从细胞到细胞的传播	Rolland, S. J.	PDF	N/A	Host PIK3C3 promotes Shigella flexneri spread from cell to cell through vacuole formation
染色质相关长链非编码RNA-剪接因子凝聚物调控预定位在核斑点附近的基因在低氧应答中的RNA加工过程	Song, Y. J.	PDF	N/A	Chromatin-associated lncRNA-splicing factor condensates regulate hypoxia responsive RNA processing of genes pre-positioned near nuclear speckles
赖氨酸乙酰乙酰化的调控元件和蛋白质底物的鉴定	Fu, Q.	PDF	N/A	Identification of the Regulatory Elements and Protein Substrates of Lysine Acetoacetylation
通过基于微芯片的大规模并行合成系统革新大规模DNA合成技术	Zhang, X.	PDF	N/A	Revolutionizing large-scale DNA synthesis with microchip-based massive in parallel synthesis system
探索短吻鲟（Acipenser brevirostrum）性腺图像的超声分形维度以进行性别鉴定	Balazadeh, K.	PDF	N/A	Exploring fractal dimensions on ultrasound of gonadal images for sex determination in shortnose sturgeon (Acipenser brevirostrum)
印度黄花木兰花蕾上四种蓟马新记录	RR, R.	PDF	N/A	New Record of Four Thrips Species Infesting Flower Buds of Magnolia champaca in India
通过三阶段释放技术将昆虫病原线虫整合到可持续有机马铃薯种植中	Anorbaev, A. R.	PDF	N/A	Integrating entomopathogenic nematodes into sustainable organic potato farming through a three-stage release technology
干旱和与维管植物的共存决定了沿海沙丘藓类群落的动态	Varela, Z.	PDF	N/A	Aridity and coexistence with vascular plants determine the dynamics of coastal dune bryophyte communities
内脏利什曼病的全球传播发生在人类历史上。	Reis-Cunha, J. L.	PDF	N/A	The global dispersal of visceral leishmaniasis occurred within human history
GENCODE：通过捕获长读长RNA测序大规模扩展长链非编码RNA目录	Kaur, G.	PDF	N/A	GENCODE: massively expanding the lncRNA catalog through capture long-read RNA sequencing
特质不确定性不容忍对行为灵活性的影响	Williams, B.	PDF	N/A	The influence of trait intolerance of uncertainty on behavioural flexibility
使用Jalview中的PaSiMap进行序列聚类	Morell, T.	PDF	N/A	Sequence clustering with PaSiMap in Jalview
5-甲基胞嘧啶和5-羟甲基胞嘧啶是结直肠癌早期检测的协同生物标志物。	Puddu, F.	PDF	N/A	5-methylcytosine and 5-hydroxymethylcytosine are synergistic biomarkers for early detection of colorectal cancer
欧洲小麦白粉病菌群体中杀菌剂抗性的基因组监测与分子进化	Minadakis, N.	PDF	N/A	Genomic surveillance and molecular evolution of fungicide resistance in European populations of wheat powderymildew
老年跑步者中ST段压低与血压反应过度的共存	Manabe, K.	PDF	N/A	Co-existence of ST-Segment Depression and Exaggerated Blood Pressure Response in Older Runners
作为活体建筑工具的共生：方法与初步成果	Faucon, P.	PDF	N/A	Inosculation As A Tool For Living Architecture: Methods And Early Results
一种基于轨迹概率分布的布尔网络吸引子景观直观可视化方法	Chong, K. H.	PDF	N/A	An intuitive method to visualize Boolean network attractors landscape based on probability distribution from trajectories
从单个词语到句子生成：共享的皮层表征，但时间动态不同	Morgan, A. M.	PDF	N/A	From single words to sentence production: Shared cortical representations but distinct temporal dynamics
触摸文本：盲人读者盲文字母表征的时空演变	Teng, S.	PDF	N/A	Touch to text: Spatiotemporal evolution of braille letter representations in blind readers
在拦截任务中，超越性能稳定的训练会增加对不可预测扰动的在线调整的使用。	Couto, C.	PDF	N/A	Practice beyond performance stabilization increases the use of online adjustments to unpredictable perturbations in an interceptive task
小鼠、猕猴和人类中单神经元时间尺度的连续层次结构	Zeisler, Z. R.	PDF	N/A	Consistent hierarchies of single-neuron timescales in mice, macaques and humans
胎盘因子XIIIA1表达减少与HIV感染孕妇长期抗逆转录病毒治疗及早产相关。	Ojwach, D.	PDF	N/A	Diminished placental Factor XIIIA1 expression associates with long term ART and preterm birth in pregnant people living with HIV.
生物气溶胶作为云凝结核的能力有限，可能限制了它们在混合相云中引发冰晶形成的潜力。	Santl-Temkiv, T.	PDF	N/A	The limited capacity of bioaerosols to serve as cloud-condensation nuclei may restrict their potential to initiate ice formation in mixed-phase clouds
mcRigor：一种用于增强单细胞数据分析中metacell划分严谨性的统计方法	Liu, P.	PDF	N/A	mcRigor: a statistical method to enhance the rigor of metacell partitioning in single-cell data analysis
# BioRxiv 2024-10-30 Papers

标题	作者	PDF链接	代码仓库	Title
撤回：呼吸道合胞病毒感染细胞中形成的一种含有病毒RNA和G蛋白的膜性细胞器的超微结构特征	Vijayakrishnan, S.	PDF	N/A	WITHDRAWN: Ultrastructural characterization of a viral RNA and G-protein containing, membranous organelle formed in respiratory syncytial virus infected cells
黏多糖贮积症III型A、B和C的小鼠模型显示出过度活跃以及少突胶质细胞状态的改变。	Gerken, E.	PDF	N/A	Zebrafish models of Mucopolysaccharidosis types IIIA, B, & C show hyperactivity and changes in oligodendrocyte state
通过活细胞单分子成像揭示的核受体相互作用网络的惊人特征	Dahal, L.	PDF	N/A	Surprising Features of Nuclear Receptor Interaction Networks Revealed by Live Cell Single Molecule Imaging
皮层-丘脑通信在熟练运动序列中的动作协调	Li, Y.	PDF	N/A	Cortico-thalamic communication for action coordination in a skilled motor sequence
从大脑频谱特征预测主体特质：应用于大脑衰老的研究	Jarne, C. G.	PDF	N/A	Predicting subject traits from brain spectral signatures: an application to brain ageing
从头注释小麦泛基因组揭示了六倍体小麦泛转录组的复杂性和多样性	White, B.	PDF	N/A	De novo annotation of the wheat pangenome reveals complexity and diversity of the hexaploid wheat pan-transcriptome
数据驱动的AI系统，用于学习如何运行转录组装器	Shen, Y.	PDF	N/A	Data-driven AI system for learning how to run transcript assemblers
一种通用且有效的去条纹变分方法：应用于光片显微镜、聚焦离子束扫描电镜和遥感图像	Rottmayer, N.	PDF	N/A	A universal and effective variational method for destriping: application to light-sheet microscopy, FIB-SEM and remote sensing images
腹侧被盖区和黑质致密部神经递质定义的细胞类型的比例和分布	Conrad, W. S.	PDF	N/A	Proportion and distribution of neurotransmitter-defined cell types in the ventral tegmental area and substantia nigra pars compacta
基于精度的因果推断调节视听时间重校准	Li, L.	PDF	N/A	Precision-based causal inference modulates audiovisual temporal recalibration
在9.4 T磁场下使用pCASL技术对啮齿动物进行高分辨率灌注成像	Pires Monteiro, S.	PDF	N/A	High-resolution perfusion imaging in rodents using pCASL at 9.4 T
导航范围扩展促进迁徙性狩猎	Zhang, Y.	PDF	N/A	Navigated range expansion promotes migratory culling
Foldclass 和 Merizo-search：基于嵌入的深度学习工具，用于蛋白质结构域分割、折叠识别和比较	Kandathil, S. M.	PDF	N/A	Foldclass and Merizo-search: embedding-based deep learning tools for protein domain segmentation, fold recognition and comparison
自上而下起源的捕食者-猎物幂律的一般机制	Mazzarisi, O.	PDF	N/A	General mechanisms for a top-down origin of the predator-prey power law
马尔可夫场网络整合多模态数据预测免疫系统扰动对猕猴静脉BCG疫苗接种的影响	Wang, S.	PDF	N/A	Markov Field network integration of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques
疟原虫感染的红细胞的细胞粘附改变了脑内皮细胞中细胞因子、组蛋白和抗病毒蛋白编码基因的表达。	Allweier, J.	PDF	N/A	Cytoadhesion of Plasmodium falciparum-infected red blood cells changes the expression of cytokine-, histone- and antiviral protein-encoding genes in brain endothelial cells
当常微分方程（ODEs）不可行时，信号传导途径的动态建模	Rachel, T. J.	PDF	N/A	Dynamic modelling of signalling pathways when ODEsare not feasible
皮质对分层节奏的追踪协调了生物运动的多感官处理	Shen, L.	PDF	N/A	Cortical tracking of hierarchical rhythms orchestrates the multisensory processing of biological motion
22q11.2缺失突变小鼠海马CA1区的抑制性动力学紊乱	Herrlinger, S. A.	PDF	N/A	Disorganized Inhibitory Dynamics in Hippocampal area CA1 of 22q11.2 Deletion Mutant Mice
利用转录因子结合和启动子表观基因组模式的可解释模型揭示了在细胞类型背景下与疾病相关的基因及其调控因子。	Chandra, O.	PDF	N/A	Explainable models using transcription factor binding and epigenome patterns at promoters reveal disease-associated genes and their regulators in the context of cell-types
使用Lamin B受体实现内质网膜接触位点的非破坏性可诱导标记	Downie, L.	PDF	N/A	Non-disruptive inducible labeling of ER-membrane contact sites using the Lamin B Receptor
埃及伊蚊的VLG-1基因挑战了Vago基因被认为具有抗病毒特性的假设。	Couderc, E.	PDF	N/A	Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes.
代谢驱动的氧化还原状态对线粒体网络形态的主动调控	Singh, G.	PDF	N/A	Active control of mitochondrial network morphology by metabolism driven redox state
运输蛋白中最低能量路径的计算。	Yorke, B. A.	PDF	N/A	Calculation of minimum energy pathways in transport proteins.
Cell Ranger版本对Chromium基因表达数据的影响	Abugessaisa, I.	PDF	N/A	Impacts of Cell Ranger versions on Chromium gene expression data
chrna3 调节斑马鱼对酒精的反应	Raine, J.	PDF	N/A	chrna3 modulates alcohol response in zebrafish
水体积、生物学重复和PCR重复影响深海浮游鱼类群落的特征化。	Peres, P. A.	PDF	N/A	Water volume, biological and PCR replicates influence the characterization of deep-sea pelagic fish communities.
高分辨率活体内运动学追踪与可注射荧光纳米颗粒	Ulutas, E. Z.	PDF	N/A	High-resolution in vivo kinematic tracking with injectable fluorescent nanoparticles
用泛扩展显微镜可视化核孔复合物的可塑性	Morgan, K. J.	PDF	N/A	Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy
母体脂联素恢复了暴露于宫内母体肥胖的成年后代阻力血管中的胆碱能血管舒张	Murphy, M.	PDF	N/A	Maternal adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero
凝聚素介导的染色质重塑调控传统树突状细胞的分化和功能	Adams, N. M.	PDF	N/A	Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells
一种宿主导向的佐剂能够复苏并增强抗生素对胞内细菌持留菌的敏感性。	Lu, K.-Y.	PDF	N/A	A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics
鉴定单性异体和雌雄同体海洋鱼类物种中性二型循环微小RNA。	Geffroy, B.	PDF	N/A	Identifying sexually dimorphic circulating microRNAs in gonochoristic and hermaphroditic marine fish species.
Prefoldin 5 是一种与微管相关的蛋白质，能够抑制Tau蛋白的聚集及其引发的神经毒性。	Bisht, A.	PDF	N/A	Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity
在古菌中由机械压缩触发的类组织多细胞发育	Rados, T.	PDF	N/A	Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea
在自然视觉过程中，人类视觉皮层早期的反应最好由扫视（saccade）的开始而不是注视（fixation）的开始来解释。	Amme, C.	PDF	N/A	Saccade onset, not fixation onset, best explains early responses across the human visual cortex during naturalistic vision
热中性环境对小鼠MASLD严重程度、肝基因表达及β3-肾上腺素能刺激下BAT激活的影响	Martin, C. M.	PDF	N/A	Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during β3-adrenergic stimulation in mice
HP1/Swi6的磷酸化减轻了其与Suv39/Clr4在核小体上的竞争，并促进了H3K9三甲基化的扩展。	Kennedy, D. R.	PDF	N/A	Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading.
在视觉引导的运动过程中，细胞类型特异性纹状体集合活动的动态失衡。	Fearey, B.	PDF	N/A	Dynamic imbalances in cell-type specific striatal ensemble activity during visually guided locomotion.
利用表达引导性抗菌肽（gAMP）的生物工程益生菌对肿瘤相关微生物F. nucleatum进行靶向治疗	Choudhury, A.	PDF	N/A	Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP)
针对肿瘤相关微生物具核梭杆菌（F. nucleatum）的靶向治疗：利用生物工程益生菌表达引导性抗菌肽（gAMP）	Choudhury, A.	PDF	N/A	Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP)
网格蛋白非依赖性内吞作用和癌细胞中的逆向运输促进了细胞毒性CD8 T细胞的激活。	Xu, S.	PDF	N/A	Clathrin-independent endocytosis and retrograde transport in cancer cells promote cytotoxic CD8 T cell activation
对纯种赛马髁部应力骨折风险评估的虚拟力学测试流程进行调整与验证	Irandoust, S.	PDF	N/A	Tuning and validation of a virtual mechanical testing pipeline for condylar stress fracture risk assessment in Thoroughbred racehorses
LIMPACAT：利用全切片成像的肝癌免疫预测多组学注意力变压器	Chiu, Y. J.	PDF	N/A	LIMPACAT：Multi-Omics Attention Transformer for Immune Prediction in Liver Cancer Using Whole-Slide Imaging
渴望联系：探索印度家庭中孕期渴望、母亲健康与儿童偏好之间的关系	Kruthi, M. N.	PDF	N/A	Craving Connections: Exploring the Relationship Between Pregnancy Cravings, Maternal Health, and Child Preferences in Indian Families
评估尼日利亚技术学院学生生物学能力与性别及生物学成绩的关系	Sowunmi, K.	PDF	N/A	Assessing Technical College Students' Biology Proficiency as Related to Gender and Performance in Biology in Nigeria
肺腺癌患者肿瘤引流静脉中循环细胞外囊泡的新型蛋白质组学特征	Tricard, J.	PDF	N/A	New proteomic signature in circulating extracellular vesicles from tumor-draining vein of lung adenocarcinomas patients
肝病变动态的个体患者数据分析：泛癌分析	Dickinson, J.	PDF	N/A	Individual Patient Data Analysis of Liver Lesion Dynamics: A Pan Cancer Analysis
双侧初级运动皮层上的双站点经颅交流电刺激增加半球间抑制并改善双手灵巧性：一项三盲、随机、假刺激对照研究	Lebihan, B.	PDF	N/A	Dual-site transcranial alternating current stimulation over the primary motor cortices increases interhemispheric inhibition and improves bimanual dexterity: A triple-blind, randomised, sham-controlled study
小脑性伸臂共济失调对运动学和动力学需求的敏感性	Oh, K.	PDF	N/A	Sensitivity of Cerebellar Reaching Ataxia to Kinematic and Dynamic Demands
CYK-4 GAP结构域调节中心纺锤体向皮质区的定位，以促进收缩环的组装并促进环的溶解	Schlientz, A. J.	PDF	N/A	The CYK-4 GAP domain regulates cortical targeting of centralspindlin to promote contractile ring assembly and facilitate ring dissolution
探索外泌体的粘附特性以用于功能性检测	Pachane, B. C.	PDF	N/A	Exploring the adhesion properties of extracellular vesicles for functional assays
野生捕获的洞穴鱼睡眠损失的系统发育图谱	North, O.	PDF	N/A	Phylogenetic mapping of sleep loss in wild-caught cavefish
双目竞争的意象启动并不是衡量个体在视觉化主观生动性方面差异的可靠指标。	Bouyer, L.	PDF	N/A	Imagery priming of binocular rivalry is not a reliable metric of individual differences in the subjective vividness of visualisations.
利用运动学时间序列数据的神经网络分析识别中风后和神经正常步态行为的独特亚型	Kuch, A.	PDF	N/A	Identification of distinct subtypes of post-stroke and neurotypical gait behaviors using neural network analysis of kinematic time series data
军事野外训练前后手部和前臂皮肤细菌群落动态变化	Glenna, S.	PDF	N/A	Skin bacterial community dynamics of hands and forearms before and after military field exercise
白细胞通过内皮膜隧道渗出血管	van der Meer, W.	PDF	N/A	Leukocytes use endothelial membrane tunnels to extravasate the vasculature
N-Myc下游调控基因-1调控整合素表达以抑制胃癌转移的机制	Wang, T.	PDF	N/A	Mechanism of N-Myc Downstream Regulated Gene-1 regulating Integrin expression to inhibit gastric cancer metastasis
PET微塑料增加了胰岛素抵抗和胰腺炎的风险	Mierzejewski, K.	PDF	N/A	PET microplastics increase the risk of insulin resistance and pancreatitis
苯并噁嗪途径与玉米硼稳态的关联	Chu, L.	PDF	N/A	Association of the benzoxazinoid pathway with boron homeostasis in maize
向日葵HaHB4基因在现代小麦中的渐渗：应对气候变化抗逆性提升的一项进展	Ayala, F.	PDF	N/A	Introgression of the sunflower HaHB4 gene in modern wheat: An advancement in resilience to deal with climate change
双侧颅内电磁刺激顶下小叶-海马网络增强人类长期记忆	Borghi, I.	PDF	N/A	Dual transcranial electromagnetic stimulation of the precuneus-hippocampus network boosts human long-term memory
一种新型早发性脊髓小脑共济失调13号BAC小鼠模型，具有小脑发育不全、震颤和共济失调步态	Yin, J.	PDF	N/A	A Novel Early Onset Spinocerebellar Ataxia 13 BAC Mouse Model with Cerebellar Hypoplasia, Tremor, and Ataxic Gait
系统性炎症和淋巴细胞活化先于类风湿性关节炎	He, Z.	PDF	N/A	Systemic inflammation and lymphocyte activation precede rheumatoid arthritis
灭绝涡旋的驱动更多地源于有益突变的匮乏，而非有害突变的积累。	Mawass, W.	PDF	N/A	Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation
病毒感染中祖细胞的基因组分析表明，糖皮质激素抑制了浆细胞样树突状细胞的生成	Jo, Y.	PDF	N/A	Genomic Analysis of Progenitors in Viral Infection Implicates Glucocorticoids as Suppressors of Plasmacytoid Dendritic Cell Generation
中等剂量辐射会损害长期造血干细胞功能，并影响对细胞毒性应激的造血恢复。	Zhang, Q.	PDF	N/A	Medium-dose irradiation impairs long-term hematopoietic stem cell functionality and hematopoietic recovery to cytotoxic stress
Ta3N5诱导U2OS人类癌细胞凋亡	Nozaki, T.	PDF	N/A	Induction of cell death in U2OS human cancer cells by Ta3N5
硅胶表面上的免疫细胞死亡会驱动生物膜的形成。	Jagirdar, S. K.	PDF	N/A	Immune cell death on silicone surfaces drives biofilm formation
探索胶质瘤细胞和细胞外囊泡中的N6-甲基腺苷及长链转录本。	Batool, S. M.	PDF	N/A	Exploring N6-Methyladenosine and long transcripts in glioma cells and extracellular vesicles.
比较时空单细胞转录组揭示了C4禾本科植物中克朗兹解剖结构出现期间现有调控的重塑	Zhao, C.	PDF	N/A	Comparative spatiotemporal single cell transcriptomes reveal rewiring of pre-existing regulations during emergence of Kranz anatomy in C4 grasses
受影响力数据驱动的科学推理：重振dfstat！	Spiess, A. N.	PDF	N/A	Scientific reasoning driven by influential data: resuscitate dfstat!
早期职业研究（ECR）中导师-学员关系的调查：对STEMM学科发表和职业发展的启示	Lordan, R.	PDF	N/A	A survey of the mentor-mentee relationship in early career research (ECR): Implications for publishing and career advancement in the STEMM disciplines
将产前和围产期风险因素与儿童皮质结构的多变量融合联系起来	Lindseth, L. R.	PDF	N/A	Linking Pre- and Perinatal Risk Factors to a Multivariate Fusion of Child Cortical Structure
Salinispora中酮霉素类似物的结构解析、生物合成基因簇分布及生物活性	Castro-Falcon, G.	PDF	N/A	Structure elucidation, biosynthetic gene cluster distribution, and biological activities of ketomemicin analogs in Salinispora
生物衰老的标志、机制和指标：范围综述	Ziesel, A.	PDF	N/A	Markers, Mechanisms and Metrics of Biological Aging: A Scoping Review
分层分析将HIF-2α确定为高度免疫浸润性黑色素瘤的治疗靶点。	Huang, A. Y.	PDF	N/A	Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas
针对SARS-CoV-2变种的中和纳米抗体的深度生成设计	Huo, L.	PDF	N/A	Deep generative design of neutralizing nanobodies againstSARS-CoV-2 variants
从菠萝（Ananas comosus）中分离出的果胶酶细菌，命名为Dickeya ananae sp. nov.	Dobhal, S.	PDF	N/A	Dickeya ananae sp. nov., pectinolytic bacterium isolated from pineapple (Ananas comosus)
奈妥匹坦对结核分枝杆菌持留菌表现出强效活性	Eldesouky, H. E.	PDF	N/A	Netupitant Exhibits Potent Activity on Mycobacterium tuberculosis Persisters
一种垂直和水平传播的RNA病毒促进寄生蜂卵的孵化	Izraeli, Y.	PDF	N/A	A Vertically and Horizontally Transmitted RNA Virus Facilitates Egg Hatching of a Parasitoid Wasp
在深海中，SAR11谱系的序列离散物种的形成基础是随机且无偏好的重组。	Zhao, J.	PDF	N/A	Promiscuous and unbiased recombination underlies the sequence-discrete species of the SAR11 lineage in the deep ocean
鉴定JC多瘤病毒中的新型环状转录本	Iida, S.	PDF	N/A	Identification of novel wraparound transcripts in JC polyomavirus
微管蛋白样蛋白CetZ1和CetZ2在古菌Haloferax volcanii的细胞形态发生中起协调作用	Brown, H. J.	PDF	N/A	Tubulin-like proteins CetZ1 and CetZ2 coordinate cellular morphogenesis in the archaeon Haloferax volcanii
由以厌氧甲烷氧化古菌（ANME archaea）为主导的共生体从烃类物质中产生甲烷	Sarno, N.	PDF	N/A	Methane production from hydrocarbons by consortia dominated by ANME archaea
RNA外切体通过调控大脑中转录本的丰度来维持细胞RNA稳态。	Higginson, L. A.	PDF	N/A	The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain
蜻蜓分子系统发育研究的新标记，包括保守组蛋白H3和H4基因的部分及它们之间的间隔区	Mglinets, A. V.	PDF	N/A	A new marker for molecular phylogenetic studies in Odonata including parts of conservative histone H3 and H4 genes and spacer between them
组蛋白乙酰转移酶p300对RORβ的乙酰化以及SIRT1的去乙酰化作用，调节了受体的稳定性、更新速率及转录活性。	O'Leary, T. R.	PDF	N/A	Acetylation of RORβ by lysine acetyltransferase p300 and deacetylation by SIRT1 modulates receptor stability, turnover and transcriptional activity.
RNA聚合酶I转录起始效率及起始位点选择的决定因素	Parilova, O.	PDF	N/A	Determinants of transcription initiation efficiency and start site selection by RNA polymerase I
静电相互作用决定了纳库巴坦对OXA-48样β-内酰胺酶的效能	Hoff, J. F.	PDF	N/A	Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases
体内特定部位的UFMylome定量分析揭示了肌球蛋白在ALS中的修饰	Blazev, R.	PDF	N/A	Site-specific quantification of the in vivo UFMylome reveals myosin modification in ALS
自文档化质粒	Peccoud, S. J.	PDF	N/A	Self-Documenting Plasmids
长上下文蛋白质语言模型	Wang, Y.	PDF	N/A	Long-context Protein Language Model
一种基于大肠杆菌染色体的动态三维聚合物模型，由光学组合筛选的数据驱动。	Schirman, D.	PDF	N/A	A dynamic 3D polymer model of the Escherichia coli chromosome driven by data from optical pooled screening
噬菌体CRISPR样调控RNA抑制细菌的适应性和先天免疫	Liu, C.	PDF	N/A	Phage CRISPR-like regulatory RNAs silence bacterial adaptive and innate immunity
全基因组抗生素-CRISPRi分析揭示了将LiaR激活作为恢复氟喹诺酮耐药性肺炎链球菌敏感性策略的发现	Sewgoolam, B.	PDF	N/A	Genome-wide antibiotic-CRISPRi profiling identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae
可咀嚼的鼠李糖乳杆菌GG在鼻腔内定植，并促进过敏性鼻结膜炎患者的局部免疫益处	De Boeck, I.	PDF	N/A	Lacticaseibacillus rhamnosus GG in a chewable colonizes the nose and facilitates local immune benefits in allergic rhinoconjunctivitis patients
磷酸盐改良剂在土壤湿润后促使RNA病毒大量繁殖	Sieradzki, E. T.	PDF	N/A	Phosphate amendment drives bloom of RNA viruses after soil wet-up
温和链球菌糖脂的生物合成及其在生理和抗生素敏感性中的作用	Wei, Y.	PDF	N/A	Biosynthesis of mitis group streptococcal glycolipids and their roles in physiology and antibiotic susceptibility
外源性脂肪酸通过在磷脂合成中与内源性和外源性生成的底物之间的竞争，抑制了大肠杆菌中的脂肪酸合成。	van den Berg, S. P. H.	PDF	N/A	Exogenous fatty acids inhibit fatty acid synthesis through competition between endogenously- and exogenously-generated substrates for phospholipid synthesis in Escherichia coli
增强型Nme2Cas9和Nme2SmuCas9核酸酶及碱基编辑器的合理设计	Bamidele, N.	PDF	N/A	Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors
SeqTagger，一个快速且精准的工具，用于解复用直接RNA纳米孔测序数据集	Pryszcz, L. P.	PDF	N/A	SeqTagger, a rapid and accurate tool to demultiplex direct RNA nanopore sequencing datasets
一种组合域筛选平台揭示了转录扰动中的表观遗传效应物相互作用	Moon, H. C.	PDF	N/A	A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation
单纯疱疹病毒1型起源结合蛋白UL9通过分子内和分子间的方式将起源DNA和非起源DNA连接和环化。	Meier, A. F.	PDF	N/A	Herpes simplex virus type 1 origin binding protein UL9 tethers and loops origin- and non-origin-DNA intra- and intermolecularly
在ORC缺陷细胞中选择性起源和MCM2-7功能的过度加载。	Shibata, Y.	PDF	N/A	Specific origin selection and excess functional MCM2-7 loading in ORC-deficient cells.
滑膜成纤维细胞中的O-糖基化驱动软骨降解	Tran, L. S.	PDF	N/A	ER O-glycosylation in synovial fibroblasts drives cartilage degradation
人类精子发生导致核孔结构和功能的减少	dos Santos, A.	PDF	N/A	Human spermatogenesis leads to a reduced nuclear pore structure and function
复合素2在调节胰岛郎格汉斯细胞激素分泌中的作用	Ng, X. W.	PDF	N/A	Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans
神经元和星形胶质细胞具有不同的细胞器特征和应激反应。	Rhoads, S. N.	PDF	N/A	Neurons and astrocytes have distinct organelle signatures and responses to stress
AlphaFold 2，而非AlphaFold 3，能够预测出对重复蛋白质具有高度信心但不切实际的beta-螺旋结构。	Pratt, O. S.	PDF	N/A	AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic beta-solenoid structures for repeat proteins
用于土壤真菌间细胞通讯多重筛选的综合平台	Schiesaro, G.	PDF	N/A	A synthetic platform for multiplex screening of cell-cell communication between soil fungi
TXNIP通过介导LAT1/SLC7A5的内吞作用，减少进入静止状态的细胞对氨基酸的摄取。	Kahlhofer, J.	PDF	N/A	TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence
# BioRxiv 2024-10-29 Papers

标题	作者	PDF链接	代码仓库	Title
将新的视觉类别雕刻进人类大脑	Iordan, C. R.	PDF	N/A	Sculpting New Visual Categories into the Human Brain
秀丽隐杆线虫中双链RNA的跨代运输可以限制可遗传的表观遗传变化	Shugarts, N.	PDF	N/A	Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes
沙门氏菌诱导的SIRT1和SIRT3对于维持细菌和宿主的代谢转换至关重要，以实现成功的致病过程。	Hajra, D.	PDF	N/A	Salmonella-induced SIRT1 and SIRT3 are crucial for maintaining the metabolic switch in bacteria and host for successful pathogenesis
将中风后手臂瘫痪中的移动和保持控制分开	Hadjiosif, A. M.	PDF	N/A	Separating the control of moving and holding in post-stroke arm paresis
阿米巴样细胞在软端极化的NMIIA作用下进行硬度趋向性运动。	Kang, C.	PDF	N/A	Amoeboid cells undergo durotaxis with soft end polarized NMIIA
系统性忽视与对变化过度和不足反应的神经计算基础	Wang, M.-C.	PDF	N/A	System Neglect and the Neurocomputational Substrates for Over- and Underreactions to Change
检测政权更迭：对变化过度反应和反应不足的神经计算基础	Wang, M.-C.	PDF	N/A	Detecting Regime Shifts: Neurocomputational Substrates for Over- and Underreactions to Change
上皮微侵袭与由疾病减毒肺炎球菌生物合成基因突变体引发的免疫反应	Weight, C. M.	PDF	N/A	Epithelial microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants
居留-殖民权衡与生态位分化使得大肠杆菌的多个谱系能在健康人体中共存	Morel-Journel, T.	PDF	N/A	Residence-colonization trade-off and niche differentiation enable the coexistence of Escherichia coli phylogroups in healthy humans
Cell2Sentence：教授大型语言模型生物学的语言	Levine, D.	PDF	N/A	Cell2Sentence: Teaching Large Language Models the Language of Biology
TgLaforin，一种葡聚糖磷酸酶，揭示了储存多糖在刚地弓形虫速殖子和缓殖子中的动态作用。	Murphy, R. D.	PDF	N/A	TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in Toxoplasma gondii tachyzoites and bradyzoites
DetectEV：一种用于评估细胞外囊泡完整性和生物活性的功能性酶学检测方法	Adamo, G.	PDF	N/A	DetectEV: a functional enzymatic assays to assess integrity and bioactivity of extracellular vesicles
通过水平基因转移获得的基因在Photorhabdus laumondii中具有共同的调控模式。	Rili, L.	PDF	N/A	Genes acquired by horizontal gene transfer share common regulatory patterns in Photorhabdus laumondii
结合进化和蛋白质语言模型，利用D2Deep实现可解释的癌症驱动突变预测	Tzavella, K.	PDF	N/A	Combining evolution and protein language models for an interpretable cancer driver mutation prediction with D2Deep
体积电子显微镜揭示了人类内嗅皮层中独特的层状突触特性	Plaza-Alonso, S.	PDF	N/A	Volume Electron Microscopy Reveals Unique Laminar Synaptic Characteristics in the Human Entorhinal Cortex
新型神经启发式控制器通过内部模型在低级肢体任务中实现了模块化泛化	Munoz, D.	PDF	N/A	New neural-inspired controller generalises modularity over lower limb tasks through internal models
behaviorMate：一种基于物联网的方法，用于适应性控制行为和基于导航的实验	Bowler, J. C.	PDF	N/A	behaviorMate: An Intranet of Things Approach for Adaptable Control of Behavioral and Navigation-Based Experiments
无偏倚地识别密集混合神经元培养物中的细胞身份	De Beuckeleer, S.	PDF	N/A	Unbiased identification of cell identity in dense mixed neural cultures
果蝇神经元类型的分裂GAL4驱动线资源	Meissner, G. W.	PDF	N/A	A split-GAL4 driver line resource for Drosophila neuron types
通过MALDI-TOF MS自动网络化录入艰难梭菌的核糖型	Sanchez-Blazquez, M.	PDF	N/A	Automated web-based typing of Clostridioides difficile ribotypes via MALDI-TOF MS
GSK3抑制改善了纽芬兰ACM患者iPSC-心肌细胞的异常收缩能力	Noort, R. J.	PDF	N/A	GSK3 inhibition ameliorates the abnormal contractility of Newfoundland ACM patient iPSC-cardiomyocytes
Omicron谱系BA.1、BA.2、BA.5.1、BQ.1、XBB.1.5、EG.5.1和JN.1.1的免疫逃逸和复制能力	Bekliz, M.	PDF	N/A	Immune escape and replicative capacity of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1
探索自噬蛋白LC3B和GABARAP的芳基亚甲基-吲哚酮配体	Leveille, A. N.	PDF	N/A	Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP
观察气孔活动：在植物体内自主成像单个气孔运动	van den Berg, T. E.	PDF	N/A	Viewing stomata in action: Autonomous in planta imaging of individual stomatal movement
选择性激动GPR34可刺激小胶质细胞摄取和清除β淀粉样纤维	Etani, H.	PDF	N/A	Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils
撤回：噬菌体与抗生素在减少铜绿假单胞菌生物膜中的协同作用	Timilsina, S.	PDF	N/A	WITHDRAWN: SYNERGISM OF BACTERIOPHAGE AND ANTIBIOTICS IN THE REDUCTION of Pseudomonas aeruginosa biofilm
癌症中通过体细胞突变破坏肿瘤抑制基因的剪接和多聚腺苷酸化信号	Kainov, Y.	PDF	N/A	Recurrent disruption of tumour suppressor genes in cancer by somatic mutations in cleavage and polyadenylation signals
我的朋友MIROSLAV：一个可破解的开源硬件和软件平台，用于在家笼中进行高通量啮齿动物活动监测	Virag, D.	PDF	N/A	My friend MIROSLAV: A Hackable Open-Source Hardware and Software Platform for High-Throughput Rodent Activity Monitoring in the Home Cage
前额叶和感觉皮层中的预备性注意模板编码了与目标相关的信息	Zhou, Z.	PDF	N/A	Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information
从电子表格实验室数据模板到知识图谱：抗微生物药物耐药性研究领域中的FAIR数据之旅	Gadiya, Y.	PDF	N/A	From spreadsheet lab data templates to knowledge graphs: A FAIR data journey in the domain of AMR research
通过卡尔曼滤波提高了全身质心位置的准确性	Le Mouel, C.	PDF	N/A	Improved accuracy of the whole body Center of Mass position through Kalman filtering
12-脂氧合酶抑制延缓人基因替代小鼠自身免疫性糖尿病的发作	Nargis, T.	PDF	N/A	12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice
级联反向积分反馈以增强稳定性和性能	M. Zand, A.	PDF	N/A	Cascaded Antithetic Integral Feedback for Enhanced Stability and Performance
利用单组分融合蛋白在酿酒酵母中对磷酸盐应答基因进行光遗传学控制	Cleere, M. M.	PDF	N/A	Optogenetic control of phosphate-responsive genes using single component fusion proteins in Saccharomyces cerevisiae
评估基于排列的推断在神经影像数据偏最小二乘分析中的应用	Danyluik, M.	PDF	N/A	Evaluating permutation-based inference for partial least squares analysis of neuroimaging data
撤回：一种可溶性膳食纤维和矿物质配方对餐后血糖调节和饱腹感的初步研究。	haynes, m. m.	PDF	N/A	WITHDRAWN: A preliminary investigation of a soluble dietary fibre and mineral formulation on post-prandial glucose regulation and satiation.
湿地石楠林的生态系统动力学：环境驱动因素对植被的空间和时间效应	Damgaard, C.	PDF	N/A	Ecosystem dynamics in wet heathlands: spatial and temporal effects of environmental drivers on the vegetation
评估模型设定和先验敏感性对贝叶斯时间信号检验的影响	Tay, J. H.	PDF	N/A	Assessing the effect of model specification and prior sensitivity on Bayesian tests of temporal signal
配体介导的内吞作用在活体骨细胞中以一种性别二态性的方式受到调控	Matthews, M. D.	PDF	N/A	Ligand-Mediated Endocytosis Is Regulated in a Sexually Dimorphic Way in Osteocytes in vivo
神经反馈训练期间反馈处理和调节重新校准的神经机制	Pamplona, G. S. P.	PDF	N/A	Neural Mechanisms of Feedback Processing and Regulation Recalibration during Neurofeedback Training
竞争和频率依赖性共同决定了沙丘石楠生态系统的群落动态	Damgaard, C.	PDF	N/A	Both competition and frequency-dependence determine community dynamics in a dune heath ecosystem
一项关于不同土壤类型和地理区域抗生素抗性基因的宏基因组研究	Pillay, S.	PDF	N/A	A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations
甲基组揭示了两种植物物种种群中最近的进化变化	Korfmann, K.	PDF	N/A	Methylomes reveal recent evolutionary changes in populations of two plant species
大规模衰老：来自狗衰老项目的年轻狗和大型品种显示出加速的表观遗传衰老。	McCoy, B. M.	PDF	N/A	Aging at scale: Younger dogs and larger breeds from the Dog Aging Project show accelerated epigenetic aging.
小锚蛋白重复蛋白（Ankyrons）对SARS-CoV-2变种的功能活性及结合特异性研究。	Park, Y.-J.	PDF	N/A	Functional Activity and Binding Specificity of small Ankyrin Repeat Proteins called Ankyrons against SARS-CoV-2 variants.
小血管脑病遗传决定因子TRIM47通过NRF2抗氧化系统调控脑稳态	Duplaa, C.	PDF	N/A	Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system
UniScore是一种通过多重搜索引擎对肽段鉴定进行统一和普遍评估的指标。	Tabata, T.	PDF	N/A	UniScore, a unified and universal measure for peptide identification by multiple search engines
微生物组知识图谱（MicrobiomeKG）：通过知识图谱连接微生物组研究与宿主健康	Goetz, S. L.	PDF	N/A	MicrobiomeKG: Bridging Microbiome Research and Host Health Through Knowledge Graphs
活性氧解毒作用有助于脓肿分枝杆菌的抗生素存活	Bates, N. A.	PDF	N/A	Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival
进化宏观生态学：在基于过程的、前向时间模拟模型中更明确地纳入系统发育信息	Culshaw, V.	PDF	N/A	Evolutionary macroecology: Incorporating phylogenetic information more explicitly into process-based, forward time, simulation models
真菌性脑膜炎病原体的表型景观揭示了其独特的生物学特性	Boucher, M.	PDF	N/A	Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology
结核菌噬菌体毒力比较研究	Rubino, I.	PDF	N/A	Comparative study on the virulence of mycobacteriophages
通过流形再现分析进行生成模型的验证	Lazzaro, N.	PDF	N/A	Generative Models Validation via Manifold Recapitulation Analysis
Neuroligin 3 突显了果蝇社交距离中的性别二态性电路	Robinson, J. W.	PDF	N/A	Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing
LYCEUM：学习在低覆盖率的古代基因组中识别拷贝数变异	Yilmaz, M.	PDF	N/A	LYCEUM: Learning to call copy number variants on low coverage ancient genomes
LYCEUM：学习在低覆盖率的古代基因组中识别拷贝数变异	Yilmaz, M. A.	PDF	N/A	LYCEUM: Learning to call copy number variants on low coverage ancient genomes
伏隔核抑制性中间神经元表达的μ阿片受体促进亲和社交行为	Toddes, C.	PDF	N/A	Mu opioid receptor expression by nucleus accumbens inhibitory interneurons promotes affiliative social behavior
细胞基因组的表观遗传限制在进化上将遗传变异与功能联系起来。	Sinniah, E.	PDF	N/A	Epigenetic constraint of cellular genomes evolutionarily links genetic variation to function
普遍且反复的杂交现象防止了欧洲最受威胁的海鸟近亲繁殖的衰退	Izquierdo-Aranega, G.	PDF	N/A	Pervasive and recurrent hybridisation prevents inbreeding depression in Europe's most threatened seabird
活动依赖性的细胞外蛋白水解级联反应重塑细胞外基质以促进结构可塑性	Singh, J. B.	PDF	N/A	Activity-dependent extracellular proteolytic cascade remodels ECM to promote structural plasticity
广泛存在的适应性权衡现象：通过快速适应在大型实验种群中揭示的果蝇（Drosophila melanogaster）	Bitter, M. C.	PDF	N/A	Pervasive fitness trade-offs revealed by rapid adaption in large experimental populations of Drosophila melanogaster
通过快速适应在大规模实验种群中揭示的普遍性适应性权衡——果蝇黑腹果蝇	Bitter, M. C.	PDF	N/A	Pervasive fitness trade-offs revealed by rapid adaptation in large experimental populations of Drosophila melanogaster
马拉维湖慈鲷中的大倒位与栖息地偏好、谱系和性别决定有关	Kumar, N. M.	PDF	N/A	Large inversions in Lake Malawi cichlids are associated with habitat preference, lineage, and sex determination
在实验性假单胞菌（Pseudomonas aeruginosa）的元种群中，快速适应和增强的遗传平行性	Chakraborty, P.	PDF	N/A	Rapid adaptation and increased genetic parallelism in experimental metapopulations of Pseudomonas aeruginosa
在秀丽隐杆线虫中Argonaute基因家族功能谱系的动态产生与消亡	Fusca, D. D.	PDF	N/A	Dynamic birth and death of Argonaute gene family functional repertoire across Caenorhabditis nematodes
DeepRNA-Twist：基于语言模型引导的RNA扭转角预测与注意力-初始网络	Abir, A. R.	PDF	N/A	DeepRNA-Twist: Language Model guided RNA Torsion Angle Prediction with Attention-Inception Network
一种利用化学交联的蛋白质整合对接的新型离散几何方法	Zhang, Y.	PDF	N/A	A new discrete-geometry approach for integrative docking of proteins using chemical crosslinks
解析Musashi-1对RNA的识别，以设计用于体外和体内应用的蛋白质和RNA突变体	Perez-Rafols, A.	PDF	N/A	Deciphering the RNA recognition by Musashi-1 to design protein and RNA mutants for in vitro and in vivo applications
SPONGE：简单先验组学网络生成器	Hovan, L.	PDF	N/A	SPONGE: Simple Prior Omics Network GEnerator
捕获单分子性质并不能确保生物分子相图的准确预测	Feito, A.	PDF	N/A	Capturing single-molecule properties does not ensure accurate prediction of biomolecular phase diagrams
来自NOD和NOR小鼠的血清及泪液自身抗体作为Sjögren's病局部和系统性炎症潜在的诊断指标	Kakan, S. S.	PDF	N/A	Serum and Tear Autoantibodies from NOD and NOR Mice as Potential Diagnostic Indicators of Local and Systemic Inflammation in Sjögren's Disease
通过单细胞RNA测序数据解析人肝第I组ILC的异质性和肿瘤相关动态	Zhang, Y.	PDF	N/A	Dissecting the Heterogeneity and Tumor-Associated Dynamics of Human Liver Group I ILC via scRNA Sequencing Data
中译：产婆蟾（Alytes）物种形成中的基因组、表型和环境相关性	Ambu, J.	PDF	N/A	Genomic, phenotypic and environmental correlates of speciation in the midwife toads (Alytes)
减数分裂驱动的代谢成本	Bradshaw, S. L.	PDF	N/A	The metabolic costs of meiotic drive
从大量组织表达数据推断基因调控的局限性	Chu, C. P.	PDF	N/A	Limits to the inference of gene regulation from bulk tissue expression data
V-和VL-评分揭示蛋白质家族的病毒特征和起源	Zhou, K.	PDF	N/A	V- and VL-Scores Uncover Viral Signatures and Origins of Protein Families
脂质分层降低高曲率囊泡出芽的能垒	Schachter, I.	PDF	N/A	Lipid Demixing Reduces Energy Barriers for High Curvature Vesicle Budding
对帕金森病相关α-突触核蛋白的核内作用结构和功能的新认识	Jos, S.	PDF	N/A	Structural and functional insights into nuclear role of Parkinson's Disease-associated α-Synuclein
IL-13/IL-13Rα2轴促进血管肉瘤细胞的增殖	Saito, H.	PDF	N/A	IL-13/IL-13Rα2 axis promotes proliferation of angiosarcoma cells
CIGB-300逆转了MDR1转染的肺鳞状癌细胞的化疗耐药性。	Wang, M.	PDF	N/A	CIGB-300 reverses chemo-resistance in MDR1-transfected lung squamous cancer cells
铜绿假单胞菌代谢物3-酮基-C12HSL通过T2R14和线粒体钙单向转运体诱导细胞凋亡	Miller, Z. A.	PDF	N/A	Pseudomonas aeruginosa metabolite 3-oxo-C12HSL induces apoptosis through T2R14 and the mitochondrial calcium uniporter
降低肝脏线粒体能量代谢会损害胃预负荷和禁食后的食物摄入调控	Ponte, M. E.	PDF	N/A	Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting
降低肝脏线粒体能量代谢会损害胃预充填和禁食后的食物摄入调控	Ponte, M. E.	PDF	N/A	Reduced Liver Mitochondrial Energy Metabolism Impairs Food Intake Regulation Following Gastric Preloads and Fasting
脂肪细胞素信号通过抑制平滑肌嘌呤能收缩性调节膀胱功能	Luo, Z.	PDF	N/A	Adiponectin Signaling Regulates Urinary Bladder Function by Blunting Smooth Muscle Purinergic Contractility
通过膜脂重塑调控外周脂肪储存能力的饮食控制	Tol, M. J.	PDF	N/A	Dietary control of peripheral adipose storage capacity through membrane lipid remodelling
一种肿瘤分泌的蛋白质利用胰高血糖素释放导致宿主消瘦。	Ding, G.	PDF	N/A	A tumor-secreted protein utilizes glucagon release to cause host wasting
钙稳态反馈控制预测心房颤动的起始、重构和进展	Moise, N.	PDF	N/A	Calcium homeostatic feedback control predicts atrial fibrillation initiation, remodeling, and progression
CpGPT：一种用于DNA甲基化的基础模型	de Lima Camillo, L. P.	PDF	N/A	CpGPT: a Foundation Model for DNA Methylation
RGS10减轻慢性炎症应激引起的全身免疫失调	Jernigan, J. E.	PDF	N/A	RGS10 Attenuates Systemic Immune Dysregulation Induced by Chronic Inflammatory Stress
工程细菌诱导的肿瘤特异性抗体促进膀胱癌免疫治疗	Rouanne, M.	PDF	N/A	Tumor-specific antibodies elicited by engineered bacteria promote bladder cancer immunotherapy
细胞因子诱导的人巨噬细胞在体外向与阿尔茨海默病相关的分子和细胞表型重编程	Podlesny-Drabiniok, A.	PDF	N/A	Cytokine-induced reprogramming of human macrophages toward Alzheimer's disease-relevant molecular and cellular phenotypes in vitro
HP1/Swi6的磷酸化缓解了其与Suv39/Clr4在核小体上的竞争，并促进了H3K9三甲基化的扩散。	Kennedy, D. R.	PDF	N/A	Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading.
CCAFE：从GWAS汇总统计数据中估计病例和对照的等位基因频率	Stoneman, H. R.	PDF	N/A	CCAFE: Estimating Case and Control Allele Frequencies from GWAS Summary Statistics
高风险MYCN扩增和高风险MYCN非扩增神经母细胞瘤患者的比较网络分析	Chang, E.	PDF	N/A	A comparative network analysis of high-risk MYCN amplified and high-risk MYCN non-amplified neuroblastoma patients
Hypermut 3：识别在特定核苷酸背景下允许多态性特征的具体突变模式	Lapp, Z.	PDF	N/A	Hypermut 3: Identifying specific mutational patterns in a defined nucleotide context that allows multistate characters
非洲刺鼠（Acomys）对致癌作用的抗性与肿瘤抑制基因的上调相关。	Vitorino, M.	PDF	N/A	Resistance to Carcinogenesis in the African Spiny Mouse (Acomys) correlates with upregulation of tumor suppressor genes.
乳铁蛋白衍生肽嵌合体诱导多发性骨髓瘤中依赖于半胱天冬酶的细胞死亡	Jang, Y.-S.	PDF	N/A	Lactoferrin-Derived Peptide Chimera Induces Caspase-independent Cell Death in Multiple Myeloma
慢性肾脏病中改变的全身生物能量储备使心脏更易出现更差的功能结果	Young, M.	PDF	N/A	Altered systemic bioenergetic reserve in chronic kidney disease predisposes hearts to worse functional outcomes
基于序列的TCR-肽表示：利用跨表位对比微调蛋白质语言模型	Im, C.	PDF	N/A	Sequence-based TCR-Peptide Representations Using Cross-Epitope Contrastive Fine-tuning of Protein Language Models
纳米尺度3D DNA追踪揭示了有丝分裂染色体自我组织的机制	Beckwith, K. S.	PDF	N/A	Nanoscale 3D DNA tracing reveals the mechanism of self-organization of mitotic chromosomes
肯尼亚西部小农玉米生产系统中农林复合种植的采用及其对土壤质量的影响	Nyuma, H. T.	PDF	N/A	Agroforestry adoption and its influence on soil quality under smallholder maize production systems in western Kenya
基于血液DNA甲基化的年龄预测	liu, R.	PDF	N/A	Age Prediction based on Blood DNA Methylation
使用酒石黄进行光学透明化可实现通过巩膜的深度光学相干断层扫描成像	Narawane, A.	PDF	N/A	Optical Clearing with Tartrazine Enables Deep Transscleral Imaging with Optical Coherence Tomography
可扩展制备坚韧且可回收的孢子承载型生物复合热塑性聚氨酯	Kim, H. S.	PDF	N/A	Scalable Fabrication of a Tough and Recyclable Spore-Bearing Biocomposite Thermoplastic Polyurethane
PAV-spotter：利用信号互相关性识别目标捕获数据中的存在/缺失变异	de Visser, M. C.	PDF	N/A	PAV-spotter: using signal cross-correlations to identify Presence/Absence Variation in target capture data
功能性便携式血液透析机XKIDNEY的评估	Lee, J. K.	PDF	N/A	Evaluation of a Functional Portable Hemodialysis Machine, XKIDNEY
分箱与分类法的结合：TaxVAMB利用双模态变分自编码器提升宏基因组分箱效果	Kutuzova, S.	PDF	N/A	Binning meets taxonomy: TaxVAMB improves metagenome binning using bi-modal variational autoencoder
使用PHILHARMONIC解码非模式生物的功能性相互作用网络	Sledzieski, S.	PDF	N/A	Decoding the Functional Interactome of Non-Model Organisms with PHILHARMONIC
面向蛋白质生成模型鲁棒性评估：对度量标准的系统分析	Strashnov, P.	PDF	N/A	Towards Robust Evaluation of Protein Generative Models: A Systematic Analysis of Metrics
蛋白质和编码序列的整合使得语言模型能够相互增强	Zhao, H.-R.	PDF	N/A	Integration of protein and coding sequences enables mutual augmentation of the language model
用于分析力激活蛋白延伸和相互作用的DNA纳米装置	Zhou, K.	PDF	N/A	DNA nanodevice for analysis of force-activated protein extension and interactions
单分子分析揭示了变体PRC1复合物介导的染色质泛素化机制	Teslenko, A.	PDF	N/A	Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes
5hmC增强PARP捕获并恢复化学抗性BRCA1/2缺陷细胞对PARP抑制剂的敏感性	Kharat, S. S.	PDF	N/A	5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells
危地马拉宫颈癌进展分析——从癌前病变到侵袭性疾病	Robinson, E.	PDF	N/A	Analysis of the progression of cervical cancer in Guatemala- from pre-malignancy to invasive disease
苔藓植物Marchantia中组织平坦性的机械调控	Ferria, J.	PDF	N/A	Mechanical regulation of tissue flatness in Marchantia
拟南芥氨基酸转运蛋白UmamiT20赋予对灰霉病菌的易感性。	Prior, M.	PDF	N/A	The Arabidopsis amino acid transporter UmamiT20 confers susceptibility to B. cinerea
AtTOC159受体通过β信号和位于C端的半乳糖脂特异性转运肽样序列，被靶向定位到叶绿体外膜。	Fish, M.	PDF	N/A	AtTOC159 Receptors are Targeted to the Chloroplast Outer Membrane by a β-Signal and Galactolipid-Specific Transit Peptide-Like Sequence at the C-Terminus
对光周期的敏感性是亚麻荠（Camelina sativa）中一种复杂的性状。	Ramirez-Corona, B.	PDF	N/A	Sensitivity to photoperiod is a complex trait in Camelina sativa
评估孟加拉国贾肖尔地区万寿菊（Tagetes erecta）栽培中田间病害的发生率和严重程度：研究结果	Shome, A.	PDF	N/A	Assessing the Incidence and Severity of Field Diseases in Marigold (Tagetes erecta) Cultivation: Results from Jashore District, Bangladesh
利用抗原和肽特征预测细菌中的免疫原性CD4+ T细胞表位	Marrama, D.	PDF	N/A	Predicting Immunogenic CD4+ T Cell Epitopes in Bacteria Using Antigen and Peptide Features
乳酸乳球菌乳亚种C60通过在肠道环境中对树突状细胞进行功能性修饰，促进B细胞产生免疫球蛋白A。	Saito, S.	PDF	N/A	Lactococcus lactis subsp. cremoris C60 promotes immunoglobulin A production from B cells through functional modification of dendritic cells in intestinal environment
通过工程化共刺激受体生成具有降低脱靶交叉反应性的T细胞	Cabezas Caballero, J.	PDF	N/A	Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors
由Arp2/3驱动的膜振荡在神经干细胞分裂期间收缩细胞间桥	LaFoya, B.	PDF	N/A	Membrane oscillations driven by Arp2/3 constrict the intercellular bridge during neural stem cell divisions
新型类肝细胞肝类器官再现了关键的成熟肝功能	Ardisasmita, A. I.	PDF	N/A	Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions
通过预测裂头绦虫（Schistocephalus solidus）的排泄/分泌蛋白和跨膜蛋白，揭示其种群间的蛋白质组分化	Wang, A.	PDF	N/A	Among-Population Differentiation in the Tapeworm Proteome through Prediction of Excretory/Secretory and Transmembrane Proteins in Schistocephalus solidus
C9orf72扩展导致不稳定的叶酸敏感性脆性位点FRA9A的形成。	Mirceta, M.	PDF	N/A	C9orf72 expansion creates the unstable folate-sensitive fragile site FRA9A
一种由自噬基因ATG9B突变引起的新型神经发育罕见疾病的特征描述	Kilic, S.	PDF	N/A	Characterization of a novel neurodevelopmental rare disease caused by a mutation within the autophagy gene ATG9B
鉴定用于选择燕麦冠锈病抗性的诊断性KASP标记	Nguyen, D. T.	PDF	N/A	Identification of diagnostic KASP markers for selection of crown rust resistance in oats
潜在致病基因的概率性精细定位	Okamoto, J.	PDF	N/A	Probabilistic Fine-mapping of Putative Causal Genes
VizCNV：一个集成平台，用于同时进行三联体基因组测序数据的相位BAF和CNV分析	Du, H.	PDF	N/A	VizCNV: An integrated platform for concurrent phased BAF and CNV analysis with trio genome sequencing data
传奇：在多模态转录组测序数据中识别共表达基因	Deng, T.	PDF	N/A	LEGEND: Identifying Co-expressed Genes in Multimodal Transcriptomic Sequencing Data
运动意识中的运动等效性	Fasola, J.	PDF	N/A	Motor Equivalence in Motor Awareness
基于物理的超快速大象鼻子建模	Kaczmarski, B. K.	PDF	N/A	Ultra-fast physics-based modeling of the elephant trunk
无标记光学活检揭示了糖尿病肾脏组织的生物分子和形态学特征，包括二维和三维	Fung, A. A.	PDF	N/A	Label-Free Optical Biopsy Reveals Biomolecular and Morphological Features of Diabetic Kidney Tissue in 2D and 3D
在循环中使用大型语言模型设计多样且高性能的蛋白质	Gomez-Uribe, C.	PDF	N/A	Designing diverse and high-performance proteins with a large language model in the loop
突破束缚：针对肝脏的无缝整合环状AAV载体的研发	Estes, B. J. G.	PDF	N/A	Breaking Free: Development of Circular AAV Cargos for Targeted Seamless Integration in the Liver
基于泛基因组的整数规划框架用于基因组推断	Chandra, G.	PDF	N/A	Integer programming framework for pangenome-based genome inference
SpatialPPI 2.0：通过图注意力网络中的残基间分析增强蛋白质-蛋白质相互作用预测	Hu, W.	PDF	N/A	SpatialPPI 2.0: Enhancing Protein-Protein Interaction Prediction through Inter-Residue Analysis in Graph Attention Networks
解析人类蛋白质中内在无序性的复杂性	de Vries, I.	PDF	N/A	Disentangling the CHAOS of intrinsic disorder in human proteins
基准测试HelixFold3预测的Holo结构用于相对自由能扰动计算	Furui, K.	PDF	N/A	Benchmarking HelixFold3-Predicted Holo Structures for Relative Free Energy Perturbation Calculations
利用智能手机RGB影像和LiDAR点云进行增强型叶片氮素和地上生物量评估——以中国菠菜为例	Harikumar, A.	PDF	N/A	Harnessing Smartphone RGB Imagery and LiDAR Point Cloud for Enhanced Leaf Nitrogen and Shoot Biomass Assessment - Chinese Spinach as a Case Study
从组学数据中统一知识驱动的网络推断	Rodriguez-Mier, P.	PDF	N/A	Unified knowledge-driven network inference from omics data
利用细胞显像图像数据进行生物活性预测的半监督对比学习	Bushiri Pwesombo, D.	PDF	N/A	Semi-supervised Contrastive Learning for Bioactivity Prediction using Cell Painting Image Data
内源性大麻素亚型选择性的动态机制	Dutta, S.	PDF	N/A	Dynamic Mechanism for Subtype Selectivity of Endocannabinoids
解开应力纤维和未成束肌动蛋白网络对细胞形状响应的皮质张力各向异性贡献的纠缠	Fage, F.	PDF	N/A	Disentangling the contributions of stress fibres and the unbundled actin meshwork to the anisotropy of cortical tension in response to cell shape
LSD1抑制减弱了BRAFV600E结直肠癌中靶向治疗诱导的谱系可塑性	Ladaika, C.	PDF	N/A	LSD1 inhibition attenuates targeted therapy-induced lineage plasticity in BRAFV600E colorectal cancer
内源性EWSR1-FLI1去泛素化位点等位基因能够调控肿瘤细胞系和异种移植模型中融合癌蛋白的表达	McGinnis, J. H.	PDF	N/A	Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts
DNA甲基化随机性与转录变异性相关，并识别出在基因定义的AML亚型中普遍存在的表观遗传干扰。	Hilgart, E.	PDF	N/A	DNA methylation stochasticity is linked to transcriptional variability and identifies convergent epigenetic disruption across genetically-defined subtypes of AML
油菜素内酯和类黄酮醇能够提高花粉管萌发和生长的温度胁迫耐受性。	Matsuura-Tokita, K.	PDF	N/A	Brassinosteroids and Flavonols Confer Temperature Stress Tolerance to Pollen Tube Germination and Growth
通过体外重组大麦Mla NLR基因鉴定效应物结合的关键功能获得性残基	Zhang, X.	PDF	N/A	Identification of a key gain-of-function residue for effector binding by in vitro shuffling of barley Mla NLR genes
急性髓系白血病与慢性髓系白血病急变期中的共享遗传与调控机制	Basu, S.	PDF	N/A	Shared Genetic and Regulatory Mechanisms in AcuteMyeloid Leukaemia and Blast Crisis Chronic MyeloidLeukaemia
晚成雏大脑与婴儿发声学习的演化	Biazzi, R. B.	PDF	N/A	Altricial brains and the evolution of infant vocal learning
眶额皮层中的神经动力学揭示了认知策略	Schiereck, S. S.	PDF	N/A	Neural dynamics in the orbitofrontal cortex reveal cognitive strategies
BT-11 在阿尔茨海默病中的再利用潜力及其作用机制的见解	Birnbaum, E. M.	PDF	N/A	BT-11 repurposing potential for Alzheimer's disease and insights into its mode of actions
神经退行性变会损害发育同步行为模式的巩固	Laufer, L.	PDF	N/A	Neurodegeneration impairs the consolidation of developmentally synchronized behavioral patterns
先验的相关性如何？贝叶斯因果推断在易变环境中的动态感知	Meijer, D.	PDF	N/A	How relevant is the prior? Bayesian causal inference for dynamic perception in volatile environments
动脉内脱氧核糖核酸酶治疗可改善老年小鼠的卒中预后	Yin, J.	PDF	N/A	Intra-arterial Deoxyribonuclease therapy improves stroke outcomes in aged mice
Ephrin介导的树突-树突排斥作用调节中枢神经系统中树突的区室特异性靶向定位	Deng, X.	PDF	N/A	Ephrin-mediated dendrite-dendrite repulsion regulates compartment- specific targeting of dendrites in the central nervous system
用于可植入神经设备的软生物相容性聚合物光纤锥	Meneghetti, M.	PDF	N/A	Soft biocompatible polymer optical fiber tapers for implantable neural devices
分泌型磷脂酶PLA2G12A通过脂解修饰胞外囊泡促进溶血磷脂信号传导，从而促进致病性Th17分化。	Mochizuki, C.	PDF	N/A	Secreted phospholipase PLA2G12A-driven lysophospholipid signaling via lipolytic modification of extracellular vesicles facilitates pathogenic Th17 differentiation
Sirtuin2阻断抑制了巨噬细胞和人源化小鼠中人类免疫缺陷病毒-1和结核分枝杆菌的复制	Singh, V. K.	PDF	N/A	Sirtuin2 blockade inhibits replication of Human Immunodeficiency Virus-1 and 1 Mycobacterium tuberculosis in macrophages and humanized mice
WAVE1和WAVE2在细胞进入过程中促进人乳头瘤病毒驱动的肌动蛋白聚合。	Fernandez, D. J.	PDF	N/A	WAVE1 and WAVE2 facilitate human papillomavirus-driven actin polymerization during cellular entry
Notch、β-连环蛋白和MAPK信号通路在双胚层动物Nematostella vectensis中分离了内胚层和中胚层。	Haillot, E.	PDF	N/A	Notch, beta-catenin and MAPK signaling segregate endoderm and mesoderm in the diploblast Nematostella vectensis
海葵生命史中基质组分的分子动力学	Bergheim, B. G.	PDF	N/A	Molecular dynamics of the matrisome across sea anemone life history
线粒体氧化还原开关授权动物形态发生的开始	Kahlin, U.	PDF	N/A	A mitochondrial redox switch licenses the onset of morphogenesis in animals
eIF4ET 调控减数分裂蛋白质组水平，以促进卵母细胞的形成和储存	Bhatia, P.	PDF	N/A	eIF4ET regulates meiotic proteome levels to enable oocyte formation and storage
西澳大利亚城市灌木丛火灾后的兰花输家和赢家：与其他特征深度整合的响应连续体	Brundrett, M. C.	PDF	N/A	Orchid losers and winners after fire in West Australian urban bushland: A response continuum deeply integrated with other traits
南极生物安全政策有效地管理了外来物种引入的比率。	Leihy, R. I.	PDF	N/A	Antarctic biosecurity policy effectively manages the rates of alien introductions
跨物种分析揭示无普遍的程序性衰老机制：斑马鱼、果蝇和线虫单细胞转录组学的见解	Niu, Y.	PDF	N/A	Cross-Species Analysis Reveals No Universal Programmed Aging Mechanism: Insights from Single-Cell Transcriptomics in Zebrafish, Fruit Fly, and Nematode
结合核基因组和线粒体基因组系统发育的生物信息学研究，以定义鞘翅目分类的关键节点	Creedy, T. J.	PDF	N/A	Bioinformatics of combined nuclear and mitochondrial phylogenomics to define key nodes for the classification of Coleoptera
深入研究基因组以精确定位XX虹鳟自发性逆转的QTL位置	Dehaullon, A.	PDF	N/A	In-depth investigation of genome to refine QTL positions for spontaneous sex-reversal in XX rainbow trout
染色体性别和性腺性别对小鼠社会动机的影响不同	Chaturvedi, S. M.	PDF	N/A	Chromosomal and gonadal sex have differing effects on social motivation in mice
Cloudgene 3：将Nextflow管道转化为强大的Web服务	Forer, L.	PDF	N/A	Cloudgene 3: Transforming Nextflow Pipelines into Powerful Web Services
scMultiNODE：多模态时间单细胞数据的整合模型	Zhang, J.	PDF	N/A	scMultiNODE: Integrative Model for Multi-Modal Temporal Single-Cell Data
GenePert：利用GenePT嵌入进行基因扰动预测	Chen, Y. T.	PDF	N/A	GenePert: Leveraging GenePT Embeddings for Gene Perturbation Prediction
通过异质性测序识别细胞反应的调节因子	Berg, K.	PDF	N/A	Identifying Modulators of Cellular Responses by Heterogeneity-sequencing
基于反应类型评分的化学酶合成规划	Li, H.	PDF	N/A	Chemoenzymatic Synthesis Planning Guided by Reaction Type Score
新孢子虫（Neospora caninum）对宿主细胞膜生物物理动力学的调控：基于超光谱成像和相量分析的LAURDAN荧光研究	Diaz, M.	PDF	N/A	Modulation of Host Cell Membrane Biophysics Dynamics by Neospora caninum: A Study Using LAURDAN Fluorescence with Hyperspectral Imaging and Phasor Analysis
LassoESM：一种专为增强套索肽性质预测而定制的语言模型	Mi, X.	PDF	N/A	LassoESM: A tailored language model for enhanced lasso peptide property prediction
从单分子荧光测量中获得的特定位置自由能表面参数，这些测量针对的是位于DNA复制叉接合处的激子耦合（iCy3）2二聚体探针	Maurer, J.	PDF	N/A	Site-specific free energy surface parameters from single-molecule fluorescence measurements of exciton-coupled (iCy3)2 dimer probes positioned at DNA replication fork junctions
成纤维细胞激活蛋白定义了局部ccRCC中与上皮-间质转化相关的侵袭性癌细胞状态和预后	Pellinen, T.	PDF	N/A	Fibroblast activation protein defines aggressive EMT-associated cancer cell state and prognosis in localized ccRCC
尤文氏肉瘤的起源：神经嵴向中胚层的胚胎重编程	Vasileva, E.	PDF	N/A	Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm
多亚基自噬捕获复合物促进胰腺癌中ER停滞的MHC-I降解。	Berquez, M.	PDF	N/A	A multi-subunit autophagic capture complex facilitates degradation of ER stalled MHC-I in pancreatic cancer.
肥胖通过激活PPARD/PDK4/ANGPTL4通路诱导胃平滑肌细胞的表型转换。	Dekkar, S.	PDF	N/A	Obesity induces phenotypic switching of gastric smooth muscle cells through the activation of the PPARD/PDK4/ANGPTL4 pathway
质体编码的RNA聚合酶构建了一个光诱导光合作用的物流链。	Gillet, F.-X.	PDF	N/A	The plastid-encoded RNA polymerase structures a logistic chain for light-induced photosynthesis
对多种普通小麦种质资源中的籽粒进行多性状评价，包括高蛋白品种	KOSINA, R.	PDF	N/A	Multi-character assessment of caryopsis in diverse common wheat germplasm,including high protein breeds
光通过解除psbA顺式ORF对翻译因子HCF173的抑制作用，激活植物中psbA的翻译。	Williams-Carrier, R.	PDF	N/A	Light activates psbA translation in plants by relieving inhibition of translation factor HCF173 by the psbA ORF in cis
铝通过ABA诱导大麦根部的木栓质生物合成	Meng, H.	PDF	N/A	Aluminium induces suberin biosynthesis in barley roots via ABA
不同年龄阶段大脑网络灵活性在运动学习中的不同作用	Uehara, K.	PDF	N/A	Distinct roles of brain network flexibility in motor learning across age
躯体运动分离将睡眠时长与社会经济背景、屏幕使用时间、认知功能和精神病理学联系起来。	Michael, C.	PDF	N/A	Somatomotor disconnection links sleep duration with socioeconomic context, screen time, cognition, and psychopathology
交易地点以换取空间：提高位置分辨率会降低海马编码中的情境容量	Rooke, S.	PDF	N/A	Trading Place for Space: Increasing Location Resolution Reduces Contextual Capacity in Hippocampal Codes
一种怀旧脑音乐接口，用于增强年轻人和老年人群体的怀旧情感、幸福感及记忆鲜活度	Sakakibara, Y.	PDF	N/A	A Nostalgia Brain-Music Interface for Enhancing Nostalgia, Well-Being, and Memory Vividness in Young and Elderly Individuals
发作相关啁啾声作为监测癫痫进展的生物标志物	Bahador, N.	PDF	N/A	Ictal-Related Chirp as a Biomarker for Monitoring Seizure Progression
工作记忆中的任务无关特征会改变当前的视觉处理	Shi, H.	PDF	N/A	Task-irrelevant features in working memory alter current visual processing
视觉引导运动过程中细胞类型特异性纹状体集合活动的动态失衡。	Howe, M.	PDF	N/A	Dynamic imbalances in cell-type specific striatal ensemble activity during visually guided locomotion.
随着年龄的增长，沉思、担忧和积极思考等情绪大脑状态的独特性也会增加。	Misaki, M.	PDF	N/A	Aging increases the distinctiveness of emotional brain states across rumination, worry, and positive thinking
哺乳期大鼠的幼崽防御行为：伏隔核壳区神经肽信号传导及其相互作用的机制	Sanson, A.	PDF	N/A	Pup defence in lactating rats: The underlying neuropeptide signalling and their interactions in the nucleus accumbens shell
基准测试用于推断TCR特异性的无监督方法	Jouannet, C.	PDF	N/A	Benchmarking unsupervised methods for inferring TCR specificity
DDO佐剂流感病毒A型核蛋白mRNA疫苗诱导出强大的体液和细胞型1免疫反应，并保护小鼠免受挑战。	Gnazzo, V.	PDF	N/A	DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge
新生儿重症监护室中母乳、捐赠母乳和母乳强化剂中的EGF和IgA	Tamar, C.	PDF	N/A	EGF and IgA in maternal milk, donor milk and milk fortifiers in the Neonatal Intensive Care Unit setting
含MT1-MMP的连接外泌体在乳腺癌进展中促进细胞外基质降解	Palmulli, R.	PDF	N/A	Tethered exosomes containing MT1-MMP contribute to extracellular matrix degradation during breast cancer progression
在基因图增强的细胞状态流形上引导细胞转变	Wang, T.	PDF	N/A	Directing cellular transitions on gene graph-enhanced cell state manifold
奥斯卡雷拉海绵属：隐藏的彩色多样性	Guiollot, E.	PDF	N/A	The Oscarella sponges genus: a hidden yet colorful diversity
多变量性状演化：基于系统发育的定量遗传G矩阵演化模型。	Blomberg, S. P.	PDF	N/A	Multivariate Trait Evolution: Models for the Evolution of the Quantitative Genetic G-Matrix on Phylogenies.
基因组洞察指导肺癌和膀胱肿瘤一线免疫治疗个性化反应	Brea-Iglesias, J.	PDF	N/A	Genomic Insights Guiding Personalized First-Line Immunotherapy Response in Lung and Bladder Tumors
探索细鳞甲螨（Oppia nitens）的基因组：环境应激响应与毒性适应	Adedokun, A. A.	PDF	N/A	Exploring The Genome of The Oribatid Mite, Oppia Nitens: Environmental Stress Response and Toxicity Adaptation
重温亚里士多德对蜜蜂的观察：蜜蜂普遍表现出高度的花期恒定性，但这种特性是由当地丰富的开花植物种类所塑造的。	Shrotri, S.	PDF	N/A	Revisiting Aristotle's observation on bees: High floral constancy is common among bees but it is shaped by the locally abundant flowering species
动态肾脏类器官微生理分析平台	Hong, S.	PDF	N/A	Dynamic Kidney Organoid Microphysiological Analysis Platform
利用大型语言模型实现异质生物医学样本元数据的自动化协调与大规模整合	Higashi, K.	PDF	N/A	Automated Harmonization and Large-Scale Integration of Heterogeneous Biomedical Sample Metadata Using Large Language Models
通过融合基于spot的空间转录组学、位置和组织学信息，利用图卷积网络推断单细胞分辨率的空间基因表达	Xue, S.	PDF	N/A	Inferring single-cell resolution spatial gene expression via fusing spot-based spatial transcriptomics, location and histology using GCN
利用系统发育和祖先序列重建方法，探索在猪与人之间传播的甲型流感病毒的遗传特征	Anker, K. M.	PDF	N/A	Exploring genetic signatures of zoonotic influenza A virus at the swine-human interface with phylogenetic and ancestral sequence reconstruction
胰腺腺泡-导管化生过渡状态的DNA甲基化记忆在没有Kras突变的情况下改变Kras下游PI3K和Rho GTPase信号传导	Feinberg, A. P.	PDF	N/A	DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation
细胞内双调蛋白对于BRCA2突变/+乳腺上皮细胞在应对复制应激时维持异染色质稳定和基因组稳定性至关重要。	Jiang, T.	PDF	N/A	Intracellular amphiregulin is critical for heterochromatin maintenance and genomic stability in response to replication stress in BRCA2mut/+mammary epithelial cells
几丁质酶-1抑制逆转了代谢失调，并在非酒精性脂肪性肝炎（MASH）动物模型中恢复了体内平衡。	Drzewicka, K.	PDF	N/A	Chitinase-1 inhibition reverses metabolic dysregulation and restores homeostasis in MASH animal models
冰与气：年轻北美鹅掌楸叶片中冻融栓塞与冰冻扩散的可视化	Johnson, K. M.	PDF	N/A	Ice and air: Visualisation of freeze-thaw embolism and freezing spread in young L. tulipifera leaves
差异基因表达分析鉴定出一组来自Solanum chacoense胚珠的防御素样肽，具有体外花粉管吸引活性。	Liu, Y.	PDF	N/A	Differential gene expression analysis identifies a group of defensin like peptides from Solanum chacoense ovules with in vitro pollen tube attraction activity
选择性育种以确定性和光周期敏感性为目标的普通豆（Phaseolus vulgaris L.）	Denning-James, K.	PDF	N/A	Selective breeding for determinacy and photoperiod sensitivity in common bean (Phaseolus vulgaris L.)
E2F4DN对p38MAPK磷酸化的抵抗通过Cited2减轻了DNA损伤诱导的神经元死亡	Llabres-Mas, A. M.	PDF	N/A	Resistance of E2F4DN to p38MAPK phosphorylation attenuates DNA damage-induced neuronal death via Cited2
双光子成像中血流动力学阻塞效应的定量分析	Yogesh, B.	PDF	N/A	Quantification of the effect of hemodynamic occlusion in two-photon imaging
一种基于功能性磁共振成像（fMRI）的方法，用于测量视觉皮层中视觉场各部分的对比度敏感度	Chow-Wing-Bom, H. T.	PDF	N/A	An fMRI-based Approach for Measuring Contrast Sensitivity Across the Visual Field in Visual Cortex
使用多线性探针在小鼠中进行经颅脑全域功能超声和超声定位显微镜	Vert, M.	PDF	N/A	Transcranial Brain-Wide Functional Ultrasound and Ultrasound Localization Microscopy in Mice using Multilinear Probes
Slit调控果蝇大脑中树突和轴突的区室特异性靶向	Deng, X.	PDF	N/A	Slit regulates compartment-specific targeting of dendrites and axons in the Drosophila brain
记忆系统的适应不良损害了背侧CA1依赖的时间绑定和陈述性记忆——以自闭症Cntnap2敲除小鼠模型为例	Rawlinson, E. C.	PDF	N/A	Maladaptation of Memory Systems Impairs Dorsal CA1-Dependent Temporal Binding and Declarative Memory in The Cntnap2 Knockout Mouse Model of Autism
揭示头颈部癌症患者对SARS-CoV-2的体液和细胞免疫反应：罗马尼亚疫苗接种与自然感染的比较研究	Marutescu, L.	PDF	N/A	Unveiling Humoral and Cellular Immune Responses to SARS-CoV-2 in Head and Neck Cancer: A Comparative Study of Vaccination and Natural Infection in Romania
假单胞菌利用混合碳源生产异戊二烯醇的替代途径导致乙酸耐受性的变化	de Siqueira, G. M. V.	PDF	N/A	Alternate routes to acetate tolerance lead to varied isoprenol production from mixed carbon sources in Pseudomonas putida
克服艰难梭菌分型中的重复性和变异性挑战	Bravo-Anton, L.	PDF	N/A	Overcoming Challenges of Reproducibility and Variability for the Clostridioides difficile typification
针对肿瘤相关微生物具核梭杆菌（F. nucleatum）的靶向治疗：利用生物工程益生菌表达引导性抗菌肽（gAMP）	Choudhury, A.	PDF	N/A	Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP)
NINJ1是HSV-1在小鼠巨噬细胞中的限制因子	Broz, P.	PDF	N/A	NINJ1 is a restriction factor for HSV-1 in mouse macrophages
温带噬菌体提高抗生素在秀丽隐杆线虫感染模型中的有效性	Fatima, R.	PDF	N/A	Temperate phages increase antibiotic effectiveness in a Caenorhabditis elegans infection model
肝素在宿主抵抗播散性念珠菌病中的关键作用	Arekar, T.	PDF	N/A	Essential role of Hepcidin in host resistance to disseminated candidiasis
Tad菌毛排列复合体的结构揭示了菌毛延伸的周质通道	Evans, S. L.	PDF	N/A	The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension
替米沙坦主要通过AT1/PPARγ轴抑制JEV感染。	Datey, A.	PDF	N/A	Telmisartan impedes JEV infection predominately via AT1/PPARγ axis
对反义抗生素耐药决定因素的系统鉴定表明，适应策略依赖于递送肽	Mulkern, A. J.	PDF	N/A	A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide
鉴定出一组基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂，能够抑制冠状病毒的复制	Pfannenstiel, J. J.	PDF	N/A	Identification of a series of pyrrolo-pyrimidine based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication
机械化学图案化定位了管腔上皮组织者的位置	Weevers, S. L.	PDF	N/A	Mechanochemical Patterning Localizes the Organizer of a Luminal Epithelium
描述外来物种对西南不列颠哥伦比亚地区单体三刺鱼（Gasterosteus aculeatus）种群形态的影响	Kienzle, H. M.	PDF	N/A	Characterizing the impacts of exotic species on the morphology of solitary threespine stickleback (Gasterosteus aculeatus) populations in southwestern British Columbia
利用真核细胞重编程的tracrRNAs在人类细胞中劫持并记录细胞内RNAs	Lee, S.-H.	PDF	N/A	Hijacking and recording intracellular RNAs in human cells using eukaryotic reprogrammed tracrRNAs
多铜氧化酶漆酶的定向进化用于细胞表面邻近标记和电子显微镜技术	Lee, S.-Y.	PDF	N/A	Directed evolution of the multicopper oxidase laccase for cell surface proximity labeling and electron microscopy
基于模式的基因组挖掘指导从海洋链霉菌中发现抗菌药物吲哚吡咯A。	Sweeney, D.	PDF	N/A	Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomycete.
碳纳米点作为红色荧光探针用于紫杉醇治疗期间DNA动力学的超分辨率显微成像	Garg, R.	PDF	N/A	Carbon nanodots as a red emissive fluorescent probe for the super-resolution microscopy of DNA dynamics during paclitaxel treatment
结核分枝杆菌mce1操纵子中长链脂肪酸辅酶A合成酶FadD5的结构酶学研究	Rahman, M. A.	PDF	N/A	Structural enzymological studies of the long chain fatty acyl-CoA synthetase FadD5 from the mce1 operon of Mycobacterium tuberculosis
VAPOR：使用传输算子的变分自编码器解耦发育中的共发生生物过程	Sheng, J.	PDF	N/A	VAPOR: Variational autoencoder with transport operators decouples co-occurring biological processes in development
DNMT3AR882H在原发性人类急性髓系白血病中并非疾病维持所必需，但与白血病干细胞频率增加相关	Koehnke, T.	PDF	N/A	DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency
核糖体生物发生超激活与ErbB信号传导介导的网络重塑导致对FGFR2抑制的适应性抗性	Zhang, T.	PDF	N/A	Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition
主基因型塑造了硬粒小麦的根系真菌群落	TRINQUIER, M.	PDF	N/A	Host genotype shapes root mycobiota in durum wheat
基于表面的深度学习皮质形状分析方法	Im, Y.	PDF	N/A	A Surface-based deep learning approach for cortical shape analysis
在并行操作和监控环境时，自适应的目光与手部协调	Fooken, J.	PDF	N/A	Adaptive Gaze and Hand Coordination while Manipulating and Monitoring the Environment in Parallel
兴奋性毒性诱导的神经营养素受体TrkB-FL的逆向运输调节高尔基体稳定性，并成为中风神经保护的靶点	Esteban-Ortega, G. M.	PDF	N/A	Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection
Ninjurin-1介导的质膜破裂是一个两步过程，需要细胞膨胀。	Hartenian, E.	PDF	N/A	Ninjurin-1 mediated plasma membrane rupture is a two-step process requiring cell swelling
白色念珠菌多药耐药ABC转运蛋白CDR1的结构、动力学和进化	Shin, J.	PDF	N/A	Structure, dynamics and evolution of the Candida albicans multi-drug resistance ABC transporter CDR1
植物化学特性及印楝素对选定人类细菌病原体的抗菌特性	Ibuot, A. A.	PDF	N/A	Phytochemical characterization and antimicrobial properties of Azadirachtin indica against selected bacterial human pathogens
年龄、性别和线粒体单倍型影响遗传多样性大鼠模型中的肠道微生物组组成和代谢物。	Nguyen, H. V. M.	PDF	N/A	Age, Sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model.
抗生素的杀伤力决定了分枝杆菌感染的结果	Jovanovic, A.	PDF	N/A	Antibiotic lethality dictates mycobacterial infection outcomes
鉴定出一大批具有广泛宿主范围的Enterobacter巨型噬菌体，这些噬菌体可感染致病性γ-变形菌	Kanhirun, N.	PDF	N/A	Identification of a large cohort of Enterobacter jumbo phages with broad host ranges across pathogenic Gammaproteobacteria
德克萨斯州分离的牛源性流感A(H5N1)病毒的复制动力学、致病性及病毒诱导的细胞反应	Mostafa, A.	PDF	N/A	Replication Kinetics, Pathogenicity and Virus-induced Cellular Responses of Cattle-origin Influenza A(H5N1) Isolates from Texas, United States
工程化多价抗体片段的结构景观及其作为结晶支架的应用	Kedari, A.	PDF	N/A	Structural landscape of engineered multivalent antibody fragments and their application as crystallization scaffolds
靶向二斑叶螨Tetranychus urticae前体rRNA的反义DNA杀螨剂作为增强真菌绿僵菌Metarhizium robertsii功效的试剂	Gavrilova, D.	PDF	N/A	Antisense DNA acaricide targeting pre-rRNA of two-spotted spider mite Tetranychus urticae as efficacy-enhancing agent of fungus Metarhizium robertsii
植物线粒体核糖体成熟与翻译的结构研究	Skaltsogiannis, V.	PDF	N/A	Structural insights into maturation and translationof a plant mitoribosome
TreeFormer：一种基于Transformer的树重排操作，用于系统发育重建	Ly-Trong, N.	PDF	N/A	TreeFormer: A transformer-based tree rearrangement operation for phylogenetic reconstruction
TaxonGPT：利用生成式人工智能进行分类学分类	Huang, H.	PDF	N/A	TaxonGPT: Taxonomic Classification Using Generative Artificial Intelligence
利用斯坦波霉素聚酮合酶中酰基转移酶的固有杂泛性进行类似物的突变合成	Su, L.	PDF	N/A	Exploiting the inherent promiscuity of the acyl transferase of the stambomycin polyketide synthase for the mutasynthesis of analogues
SCAD递送平台：一种高效的中枢神经系统和肝外寡核苷酸治疗的新方法	Kang, M.	PDF	N/A	SCAD Delivery Platform: A Novel Approach for Efficient CNS and Extrahepatic Oligonucleotide Therapeutics
突变株和非突变株枯草芽孢杆菌对利用西瓜籽生产奥吉里（ogiri）的微生物多样性及理化性质的影响	Babatuyi, C.	PDF	N/A	Effects of mutant and non-mutant strains of Bacillus subtilis to produce ogiri from Citrullus vulgaris seeds on their microbial diversity and physicochemical properties
一种紧密调控酵母RNA稳态的共转录机制	Esteban-Serna, S.	PDF	N/A	A co-transcriptional mechanism for tightly controlling RNA homeostasis in yeast
从数千个随机内含子中学习的内含子介导增强的序列决定因素	Kowal, E. J.	PDF	N/A	Sequence determinants of intron-mediated enhancement learned from thousands of random introns
研究泼尼松龙对杜氏肌营养不良小鼠模型行为的影响	Verhaeg, M.	PDF	N/A	Investigating the effects of prednisolone on behavior in mouse models of Duchenne muscular dystrophy
共享转录组特征揭示了突触修剪作为阿尔茨海默病与癫痫之间的联系	Li, H.	PDF	N/A	Shared Transcriptomic Signatures Reveal Synaptic Pruning as a Link Between Alzheimer's Disease and Epilepsy
皮质-伏隔核通路的转录组分析揭示了应激易感性背后的性别特异性改变	Pessoni, A. M.	PDF	N/A	Transcriptional profiling of the cortico-accumbal pathway reveals sex-specific alterations underlying stress susceptibility
通过表达谱分析和结构分析揭示重复基因的功能命运	Warwick Vesztrocy, A.	PDF	N/A	Unveiling the Functional Fate of Duplicated Genes Through Expression Profiling and Structural Analysis
通过适当建模遗传、环境和社会文化因素，提高在代表性不足群体中的全基因组关联研究（GWAS）表现	Cataldo-Ramirez, C.	PDF	N/A	Improving GWAS performance in underrepresented groups by appropriate modeling of genetics, environment, and sociocultural factors
学习推断传递性：前运动皮层中对心理直线上序列排序的推断	Raglio, S.	PDF	N/A	Learning to infer transitively: serial ordering on a mental line in premotor cortex
# BioRxiv 2024-10-28 Papers

标题	作者	PDF链接	代码仓库	Title
影响单基因树年代测定准确性和精确性的因素	Louvel, G.	PDF	N/A	Factors influencing the accuracy and precision in dating single gene trees
性染色体基因表达与雌性斑胸草雀在激素调控后的鸣叫学习相关	Davenport, M.	PDF	N/A	Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches
系统发育状态依赖性多样化模型（SSEs）的隐藏模型空间：一致性、挑战与机遇	Tarasov, S.	PDF	N/A	The Hidden Model Space of Phylogenetic State-Dependent Diversification Models (SSEs): Congruence, Challenges, and Opportunities
脑细胞外基质中的不可移动阴离子成分取代了细胞外氯离子	Normoyle, K. P.	PDF	N/A	Displacement of extracellular chloride by immobile anionic constituents of the brain's extracellular matrix
BiATNovo：一种基于注意力机制的双向从头测序框架，用于数据非依赖性采集质谱分析	Yang, S.	PDF	N/A	BiATNovo: An Attention-based Bidirectional De Novo Sequencing Framework for Data-Independent-Acquisition Mass Spectrometry
从贝叶斯到达尔文：基于采样的贝叶斯推断作为进化搜索的一种前适应	Csillag, M.	PDF	N/A	From Bayes to Darwin: evolutionary search as an exaptation from sampling-based Bayesian inference
听觉皮层解剖结构反映了多语言的语音经验。	Kepinska, O.	PDF	N/A	Auditory cortex anatomy reflects multilingual phonological experience
I-SVVS：整合随机变分变量选择方法，用于探索多组学微生物组数据的联合模式	Dang, T.	PDF	N/A	I-SVVS: Integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data
HSF-DREB-MYB转录调控模块调控香蕉（Musa acuminata）中黄酮醇生物合成及黄酮类B环羟基化	Naik, J.	PDF	N/A	The HSF-DREB-MYB transcriptional regulatory module regulates flavonol biosynthesis and flavonoid B-ring hydroxylation in banana(Musa acuminata)
Extramacrochaetae 通过非凋亡性胱天蛋白酶活性调节果蝇眼中的 Notch 信号传导	Baker, N. E.	PDF	N/A	Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity
可视化液-液相变	Sahoo, B. R.	PDF	N/A	Visualizing liquid-liquid phase transitions
过度表达人类RAMP1的小鼠对治疗运动敏感性的偏头痛疗法具有抵抗力。	Rahman, S. M.	PDF	N/A	Human RAMP1 overexpressing mice are resistant to migraine therapies for motion sensitivity
片段扩增的转录组和蛋白质组学影响	Fritts, R. K.	PDF	N/A	The transcriptomic and proteomic ramifications of segmental amplification
各方面都极端：由于种群数量持续偏小，雪豹的遗传多样性极低	Solari, K. A.	PDF	N/A	Extreme in Every Way: Exceedingly Low Genetic Diversity in Snow Leopards Due to Persistently Small Population Size
一氧化氮调节小鼠视网膜神经节细胞中的一部分对比度抑制作用	Gonschorek, D.	PDF	N/A	Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells
胚胎来源的脑内常驻巨噬细胞维持睡眠-觉醒回路	Seifinejad, A.	PDF	N/A	Embryo-derived brain-resident macrophages sustain sleep-wake circuits
地理分布广泛且新型的嗜血支原体和巴尔通体在墨西哥无尾蝙蝠及其同域分布的北美蝙蝠物种中的发现	Becker, D.	PDF	N/A	Geographically widespread and novel hemotropic mycoplasmas and bartonellae in Mexican free-tailed bats and sympatric North American bat species
基于多种减毒机制的减毒活SARS-CoV-2疫苗候选株的免疫原性和安全性	Suzuki, M.	PDF	N/A	Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms
抑制NFAT会促进人体组织驻留型子宫自然杀伤细胞的丧失，并伴随妊娠并发症的发生。	Asiimwe, R.	PDF	N/A	Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans
Smad4和TGF-β1依赖的基因表达生物标志物在条件性肠道腺瘤、类器官和结直肠癌中的研究。	Surakhy, M.	PDF	N/A	Smad4 and TGF-β1 dependent gene expression biomarkers in conditional intestinal adenoma, organoids and colorectal cancer.
脂氧素B4和眼压对视神经中疾病相关小胶质细胞的调控	Maurya, S.	PDF	N/A	Regulation of Diseases-Associated Microglia in the Optic Nerve by Lipoxin B4 and Ocular Hypertension
人类气道巨噬细胞在IFN-γ的作用下发生代谢重编程，导致依赖糖酵解的功能可塑性。	Cox, D. J.	PDF	N/A	Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity.
Sir2和Fun30通过Mcm解旋酶定位和核小体占据来调节核糖体DNA复制时序	Lichauco, C.	PDF	N/A	Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy
Tcf21作为创始转录因子在指定Foxd1细胞为近球小管细胞谱系中的作用	Anjum, H.	PDF	N/A	Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage
启用微观真实大脑的电场模型	Qi, Z.	PDF	N/A	Enabling Electric Field Model of Microscopically Realistic Brain
快速且灵敏的蛋白质复合物比对工具：Foldseek-Multimer	Kim, W.	PDF	N/A	Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer
Panx1敲除通过改变AMPK/mTOR信号通路和突触组成加剧了斑马鱼中的氧化应激和细胞死亡	Zoidl, G. S. O.	PDF	N/A	Panx1 Ablation Aggravates Oxidative Stress and Cell Death by Altering AMPK/mTOR signaling Pathways and the Composition of Synapses in the Zebrafish
开放通道液滴微流控平台用于被动生成人类精子微滴	Nicholson, T. M.	PDF	N/A	Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets
揭示从序列中得出的蛋白质结构域中的保守别构热点	Hacisuleyman, A.	PDF	N/A	Unveiling Conserved Allosteric Hot Spots in Protein Domains from Sequences
古代基因组揭示了公元9至10世纪在喀尔巴阡盆地发生的阿瓦尔-匈牙利转变	Gerber, D.	PDF	N/A	Ancient genomes reveal Avar-Hungarian transformations in the 9-10th centuries CE in the Carpathian Basin
生活在金属污染河流中的褐鳟的基因组特征及对金属耐受性的转录反应	Paris, J. R.	PDF	N/A	The genomic signature and transcriptional response of metal tolerance in brown trout inhabiting metal-polluted rivers
建模进化谱系的速率并预测扩散模式	Bastide, P.	PDF	N/A	Modeling the velocity of evolving lineages and predicting dispersal patterns
内侧纹状体核中GABA/谷氨酸共传递神经元对选择方向和结果的混合表征	Locantore, J.	PDF	N/A	Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleus
综合网络分析揭示阿尔茨海默病中Aβ-Tau相互作用的新型调节因子	Kitani, A.	PDF	N/A	Integrative Network Analysis Reveals Novel Moderators of Aβ-Tau Interaction in Alzheimer's Disease
细胞单层中的信息传递：一项数值研究	Nałecz-Jawecki, P.	PDF	N/A	Information transmission in a cell monolayer: A numerical study
在发育过程中处于复杂声学环境中的斑胸草雀，其听觉感知和编码效率得到了增强。	Moseley, S. M.	PDF	N/A	A complex acoustical environment during development enhances auditory perception and coding efficiency in the zebra finch
前馈网络中信号汇聚和发散的尖峰编码的时间分辨率	Mobille, Z.	PDF	N/A	Temporal resolution of spike coding in feedforward networks with signal convergence and divergence
提高中欧和东欧家庭花园的生物多样性需要区域性的策略	Varga-Szilay, Z.	PDF	N/A	Improving biodiversity in Central and Eastern European domestic gardens needs regionally scaled strategies
Biom3d，一个模块化的框架，用于托管和开发3D分割方法	Mougeot, G.	PDF	N/A	Biom3d, a modular framework to host and develop 3D segmentation methods
鉴定B群链球菌中的乙二醛酶A及其对甲基乙二醛耐受性和毒力的贡献	Akbari, M. S.	PDF	N/A	Identification of Glyoxalase A in Group B Streptococcus and its contribution to methylglyoxal tolerance and virulence
肥胖中铁死亡的调控：饮食限制和运动的肌肉类型特异性效应	Ji, F.	PDF	N/A	Regulation of Ferroptosis in Obesity: Muscle Type-Specific Effects of Dietary Restriction and Exercise
虚弱综合征对骨骼肌组织学的影响：运动的预防作用	Ji, F.	PDF	N/A	The Impact of Frailty Syndrome on Skeletal Muscle Histology: Preventive Effects of Exercise
ADAM通过与大型蛋白质复合物相互作用，调控组蛋白修饰、基因表达和剪接过程。	Pandey, A.	PDF	N/A	ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing.
棉花纤维细胞壁性质的发育变异性与重要的农艺性状相关联	Wilson, M. C.	PDF	N/A	Developmental variability in cotton fiber cell wall properties linked to important agronomic traits
通过BONCAT和基于点击化学的新合成蛋白质富集技术追踪微生物群落中的活跃成员	Hellwig, P.	PDF	N/A	Tracing active members in microbial communities by BONCAT and click chemistry-based enrichment of newly synthesised proteins
基于秀丽隐杆线虫毒性测试的自动化微流控平台	Wu, J.	PDF	N/A	An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans
乙醇培养物中Cyberlindnera jadinii的生理定量与生物量组成	Vieira-Lara, M. A.	PDF	N/A	Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures
通过整合机制建模和深度学习发现可解释的模式规则	Lu, J.	PDF	N/A	Discovery of interpretable patterning rules by integrating mechanistic modeling and deep learning
特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了编码不同运动障碍行为的机制。	Alcacer, C.	PDF	N/A	Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering
作物育种中基因组预测集成方法预测性能的改进	Tomura, S.	PDF	N/A	Improvements in Prediction Performance of Ensemble Approaches for Genomic Prediction in Crop Breeding
通过蛋白质组学检测ESKAPE病原体的抗生素抗性并同时鉴定其物种	Blumenscheit, C.	PDF	N/A	Antibiotic resistance detection and concomitant species identification of ESKAPE pathogens by proteomics
在小鼠齿状回中，5-HT7受体的激活并不影响穿通路径突触处的θ脉冲诱导的可塑性。	Siwiec, M.	PDF	N/A	Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse
基于深度学习的基因扰动效应预测尚未超越简单的线性方法。	Ahlmann-Eltze, C.	PDF	N/A	Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods
CAR Treg与抗CD154协同作用介导感染性耐受，以决定心脏移植结果。	Durgam, S. S.	PDF	N/A	CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes.
催产素受体调控草原田鼠配对结合和发育的不同方面	Sharma, R.	PDF	N/A	Oxytocin receptor controls distinct components of pair bonding and development in prairie voles
编码于自我扩增RNA中的广谱免疫抑制能够实现持续、可逆且非免疫刺激性的表达。	Lim, T. K. Y.	PDF	N/A	Broad-spectrum immune suppression encoded in self-amplifying RNA enables sustained, reversible, and non-immunostimulatory expression
区间删失对生物高通量筛选中数据准确性和机器学习性能的影响	Doffini, V.	PDF	N/A	Impact of Interval Censoring on Data Accuracy and Machine Learning Performance in Biological High-Throughput Screening
甲基组揭示了两种植物物种种群中最近的进化变化	Korfmann, K.	PDF	N/A	Methylomes reveal recent evolutionary changes in populations of two plant species
单细胞核测序揭示肾上腺皮质癌中的复制压力	Popova, L. V.	PDF	N/A	Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma
高血压中的肠道微生物代谢通量紊乱	Wenkai, L.	PDF	N/A	Gut microbial metabolic flux disorder in hypertension
甲虫-真菌互利共生体系中共生真菌的基因组多样化	Huang, Y.-T.	PDF	N/A	Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis
CXCL10/CXCR3信号传导引发神经衰老及认知障碍	Patel, M.	PDF	N/A	CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments
艺术的隐秘拓扑：一扇通往人类感知的大门	Dmitruk, E.	PDF	N/A	Art's Hidden Topology: A window into human perception
人类谱系的深度合并历史	Cousins, T.	PDF	N/A	Deep coalescent history of the hominin lineage
年龄相关的大脑成熟与年轻化：丰富环境中神经3D染色质互作组的演变	Gancedo-Verdejo, J.	PDF	N/A	Age-Dependent Maturation and Rejuvenation of the Neural 3D Chromatin Interactome in Enriched Environments
在早更新世至中更新世过渡期间，人类经历了严重瓶颈的证据不足。	Cousins, T.	PDF	N/A	Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition
四刺鱼（Apeltes quadracus）具有XY性染色体系统，其X和Y染色体上均存在多态性倒位。	Liu, Z.	PDF	N/A	The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes
一种I型3' UTR衍生的sRNA参与了金黄色葡萄球菌中的血红素代谢和毒力	Silard, C.	PDF	N/A	A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus
可分离的默认模式网络连接模式在精神病风险中导致不同的症状	Ajunwa, C. C.	PDF	N/A	Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk
身体游走揭示了思维的具身维度，具有独特的影响和神经特征。	Banellis, L.	PDF	N/A	Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures
斑马鱼中个体保守神经元微外显子和其主调控因子的表型影响	Lopez-Blanch, L.	PDF	N/A	Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish
具有多种中间神经元类型的皮层网络在预测编码过程中产生振荡模式	Lee, K.	PDF	N/A	Cortical networks with multiple interneuron types generate oscillatory patterns during predictive coding
运动补偿而非感觉误差调节自然言语生成中的序列依赖性	Lu, Y.	PDF	N/A	Motor compensations, not sensory errors, regulate serial dependence in naturalistic speech production
小鼠少突胶质前体细胞在整个生命周期中的转录组特征	Heo, D.	PDF	N/A	Transcriptional profiles of murine oligodendrocyte precursor cells across the lifespan
优势逆转保护了在时间变化环境中具有较大效应的抗性多态性	Karageorgi, M.	PDF	N/A	Dominance reversal protects large-effect resistance polymorphisms in temporally varying environments
蚂蚁导航行为的比较研究	Shen, X.	PDF	N/A	A comparative study of navigation behaviours in ants
昆虫生物群图集数据：瑞典和马达加斯加陆生节肢动物的元条形码调查	Miraldo, A.	PDF	N/A	Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar
解析南美洲沿海洛马斯植物多样性的逆纬度梯度：环境和地理因素的影响	Gonzales, F. N.	PDF	N/A	Unraveling the inverse latitudinal gradient: Environmental and geographic influences on plant diversity in South American coastal lomas
气候、天气和地理因素共同塑造了北美西部种子质量的变化和下降趋势。	Lenzo, L.	PDF	N/A	Climate, weather, and geography shape seed mass variation and decline across western North America
发展新技术以保护生态系统：采用适应性管理进行规划	Pascal, L. V.	PDF	N/A	Developing new technologies to protect ecosystems: planning with adaptive management
改进入侵蓝蟹（Callinectes sapidus）的监测：结合环境DNA和公民观察	Delrieu-Trottin, E.	PDF	N/A	Improving the monitoring of the invasive Blue Crab (Callinectes sapidus): combining environmental DNA and citizen observations
腺嘌呤DNA甲基化与转录相关，在真核生物中广泛存在。	Romero Charria, P.	PDF	N/A	Adenine DNA methylation associated to transcription is widespread across eukaryotes
通过花粉间接从头再生实现药用型大麻（Cannabis sativa L.）的双单倍体发育。	Tonolo, F.	PDF	N/A	Double haploid development in drug-type Cannabis sativa L. through microspore indirect de-novo plant regeneration.
基于受体的蛋白质结合在天鹅绒虫粘液的超分子网络中	Hu, Z.	PDF	N/A	Receptor-based protein binding in the supramolecular network of velvet worm slime
Muscle-3D：可扩展的多重蛋白质结构比对	Edgar, R. C.	PDF	N/A	Muscle-3D: scalable multiple protein structure alignment
经典的统计方法在识别乳腺癌患者生存的新靶点方面具有强大的作用。	Insawang, B.	PDF	N/A	Classical statistical methods are powerful for the identification of novel targets for the survival of breast cancer patients
解决脊椎动物古生物学中的“个体发育问题”	Napoli, J.	PDF	N/A	Resolving the "Ontogeny Problem" in Vertebrate Paleontology
眼见不为实？改善科学博士生导师关系的视角获取干预的混合效应	Tuma, T. T.	PDF	N/A	Seeing isn't believing? Mixed effects of a perspective-getting intervention to improve mentoring relationships for science doctoral students
Nematostella Wnt/β-catenin破坏复合体为理解主要后生动物信号转导途径调控的进化提供了见解。	Sun, H.	PDF	N/A	The Nematostella Wnt/β-catenin destruction complex provides insight into the evolution of the regulation of a major metazoan signal transduction pathway
在喀斯特天窗中的长期杂交揭示了洞穴鱼类眼睛丧失的遗传基础	Kellermeyer, R.	PDF	N/A	Long-term hybridization in a karst window reveals the genetic basis of eye loss in cavefish
五个甜瓜（Cucumis melo L.）品种Ananas、Canton、PI 414723、Vedrantais和Zhimali的核与细胞器基因组组装，这些品种属于不同的植物分类群。	Belinchon-Moreno, J.	PDF	N/A	Nuclear and organelle genome assemblies of five Cucumis melo L. accessions, Ananas, Canton, PI 414723, Vedrantais and Zhimali, belonging to diverse botanical groups
前列腺癌中的miRNA生物标志物：利用机器学习提高诊断准确性	Singh, S.	PDF	N/A	miRNA Biomarkers in Prostate Cancer: Leveraging Machine Learning for Improved Diagnostic Accuracy
自动催化组装的一种嵌合氨基酸-RNA合成酶核酶	Radakovic, A.	PDF	N/A	Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme
开发自主神经系统多尺度神经连接知识库	Imam, F. T.	PDF	N/A	Developing a Multiscale Neural Connectivity Knowledgebase of the Autonomic Nervous System
APOBEC3A通过改变上皮间质转化驱动卵巢癌的转移	Devenport, J. M.	PDF	N/A	APOBEC3A drives metastasis of ovarian cancer by altering epithelial-to-mesenchymal transition
通过比较基因组学和西部合鸣蛙的新染色体水平基因组，揭示了两栖类的宏观共线性、“叛逆”基因和新性连锁区域	Chen, Y.	PDF	N/A	Insights on macrosynteny, 'rebel' genes, and a new sex-linked region in anurans from comparative genomics and a new chromosome-level genome for the western chorus frog
阿尔茨海默病人类大脑中长非编码RNA的空间表达	Ng, B.	PDF	N/A	Spatial Expression of Long Non-Coding RNAs in Human Brains of Alzheimer's Disease
数字降噪处理对皮层下言语编码的影响及其与行为结果的关系	Kim, S.	PDF	N/A	Effect of digital noise-reduction processing on subcortical speech encoding and relationship to behavioral outcomes
时间上下文对多时间尺度视觉的影响	Lee, K.	PDF	N/A	The influence of temporal context on vision over multiple time scales
阿尔茨海默病患者的脑提取物在血管化神经免疫类器官中诱导多种病理，用于疾病建模和药物发现	Ji, Y.	PDF	N/A	Alzheimer's Disease Patient Brain Extracts Induce Multiple Pathologies in Vascularized Neuroimmune Organoids for Disease Modeling and Drug Discovery
左乙拉西坦通过SV2a依赖性调节阿尔茨海默病模型中App加工过程，从而抑制Aβ42的产生。	Rao, N. R.	PDF	N/A	Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer's disease models
体育活动在缓解与年龄相关的步态神经肌肉控制变化中的作用	Nunez-Lisboa, M. A.	PDF	N/A	The Role of Physical Activity in Mitigating Age-Related Changes in the Neuromuscular Control of Gait
NAD+及EVA1-C依赖的神经功能缺陷逆转，是通过在tau病动物模型中差异性选择性RNA剪接介导的。	Ai, R.	PDF	N/A	NAD+ - and EVA1-C-dependent reversal of neurological deficits is mediated by differential alternative RNA splicing in tauopathic animal models
跨眼跳空间更新和错位定位的电路模型	Wang, X.	PDF	N/A	A circuit model for transsaccadic space updating and mislocalization
听觉皮层中的正交频谱和时间包络表示	Takahashi, K.	PDF	N/A	Orthogonal spectral and temporal envelope representation in auditory cortex
急性有氧运动增强活跃个体的联想学习能力，但对久坐个体无此效果。	Gultig, K. D.	PDF	N/A	Acute Aerobic Exercise Enhances Associative Learning in Active but not Sedentary Individuals
多模态成像结合单突触分析中的突触组成、活性、mRNA翻译及动态变化	Falkovich, R.	PDF	N/A	Synaptic composition, activity, mRNA translation and dynamics in combined single-synapse profiling using multimodal imaging
化学感觉对斑马鱼幼体眼部与身体协调的调控	Sy, S. K. H.	PDF	N/A	Chemosensory modulation of eye-body coordination in larval zebrafish
恢复与多发性硬化症相关的肠道吲哚代谢物失衡可促进髓鞘再生并抑制神经炎症	Jank, L.	PDF	N/A	Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation
神经场理论作为一种框架，用于建模和理解大脑中的意识状态	Polyakov, D.	PDF	N/A	Neural field theory as a framework for modeling and understanding consciousness states in the brain
慢波睡眠与老年人的伏隔核体积有关	Ban, K.	PDF	N/A	Slow-wave sleep is associated with nucleus accumbens volume in elderly adults
在普通狨猴中进行的微创皮层脑电图（ECoG）记录	Spadacenta, S.	PDF	N/A	Minimally invasive electrocorticography (ECoG) recording in common marmosets
绘制成年期全生命周期的海马体-小脑功能连接图	Apasamy, K.	PDF	N/A	Mapping hippocampal-cerebellar functional connectivity across the adult lifespan
由局部抑制性回路调节的皮层再激活介导记忆巩固	Lensjo, K. K.	PDF	N/A	Cortical Reactivations Modulated by Local InhibitoryCircuits Mediate Memory Consolidation
前下丘脑回路调控应激易感性	Pennington, Z. T.	PDF	N/A	An anterior hypothalamic circuit gates stress vulnerability
屏状核对于维持工作记忆信息至关重要。	Bhattacharjee, A. S.	PDF	N/A	The claustrum is critical for maintaining working memory information
利用个体特异的几何和连接组特征模式重建皮层功能图谱	Olsen, A. S.	PDF	N/A	On reconstruction of cortical functional maps using subject-specific geometric and connectome eigenmodes
fNIRS研究中的包容性：量化头发和皮肤特征对信号质量的影响，并提供实用的改进建议	Yücel, M. A.	PDF	N/A	Inclusivity in fNIRS Studies: Quantifying the Impact of Hair and Skin Characteristics on Signal Quality with Practical Recommendations for Improvement
自闭症患者5-40岁期间的异常语言网络动态	Hu, Z.	PDF	N/A	The aberrant language network dynamics in autism ages 5-40 years
在搜索过程中，通过观察工作记忆来验证潜在目标	Wang, S.	PDF	N/A	Looking into working memory to verify potential targets during search
早期社会隔离应激诱导的自然行为变化与雌性大鼠成年期暴食行为相关	Simon, T. B.	PDF	N/A	Shifts in Naturalistic Behaviors Induced by Early Social Isolation Stress are Associated with Adult Binge-like Eating in Female Rats
人脑新皮层中快速放电中间神经元的动作电位发放阈值降低的机制与目的	Bakos, E.	PDF	N/A	Mechanisms and purpose of lowered action potential firing threshold in fast-spiking interneurons in the human neocortex
儿茶酚胺减少选择历史偏差	de Gee, J. W.	PDF	N/A	Catecholamines reduce choice history biases
节奏与背景（RnB）：睡眠记录的光谱分析	Dube, J.	PDF	N/A	Rhythms and Background (RnB): The Spectroscopy of Sleep Recordings
探索记忆回放在目标记忆再激活和鸟鸣发育中的作用：来自互补学习系统计算模型的见解	Lu, Y.	PDF	N/A	Exploring the roles of memory replay in targeted memory reactivation and birdsong development: Insights from computational models of complementary learning systems
Foxn3是调控发育中鼠视网膜纤毛基因的转录网络的一部分。	Zhang, H.	PDF	N/A	Foxn3 is part of a transcriptional network that regulates cilia genes in the developing mouse retina
Frem2敲除小鼠表现出Fraser综合征的表型，并因双侧肾发育不全而导致新生期死亡。	Simikyan, R. G.	PDF	N/A	Frem2 Knockout Mice Exhibit Fraser Syndrome Phenotypes and Neonatal Lethality Due to Bilateral Renal Agenesis
制作神经机器人与嵌合体栉水母	Moroz, L. L.	PDF	N/A	Making Neurobots and Chimerical Ctenophores
在捕食下的椋鸟群聚	Papadopoulou, M.	PDF	N/A	Starling murmurations under predation
觅食关联与合作繁殖鸟类中的帮助行为有关	Ferreira, A. C.	PDF	N/A	Foraging associations are related with helping interactions in a cooperatively breeding bird
我该留下还是离开？带有时间折扣的广义边际价值理论	Zylberberg, J.	PDF	N/A	Should I stay or should I go? Generalized marginal value theorem with temporal discounting
温度影响果蝇同种和异种交配率	Rader, J. A.	PDF	N/A	Temperature affects conspecific and heterospecific mating rates in Drosophila
探究生物质前体合成作为微生物适应非适应碳源的关键因素	Cai, J.	PDF	N/A	Probing Biomass Precursor Synthesis as a Key Factor in Microbial Adaptation to Unadapted Carbon Sources
FoldMark：通过水印技术保护蛋白质生成模型	ZHANG, Z.	PDF	N/A	FoldMark: Protecting Protein Generative Models with Watermarking
利用幂后验进行突变特征的稳健发现	Xue, C.	PDF	N/A	Robust discovery of mutational signatures using power posteriors
scGenePT：语言模型是否足以模拟单细胞扰动？	Istrate, A.-M.	PDF	N/A	scGenePT: Is language all you need for modeling single-cell perturbations?
使用突变特异性小分子激活p53Y220C	Zhu, X.	PDF	N/A	Activating p53Y220C with a Mutant-Specific Small Molecule
导致远端肾小管酸中毒的SLC4A1突变会改变胞质pH值和细胞自噬	Essuman, G.	PDF	N/A	SLC4A1 MUTATIONS THAT CAUSE DISTAL RENAL TUBULAR ACIDOSIS ALTER CYTOPLASMIC PH AND CELLULAR AUTOPHAGY
小脑炎症与神经退行性变在新型的脊髓小脑共济失调13型小鼠模型中的关联	Yin, J.	PDF	N/A	Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model
青少年多巴胺神经元中Grin2a的减少会导致异常的显著性和相关精神病性症状	Kielhold, M. L.	PDF	N/A	Reductions of Grin2a in adolescent dopamine neurons confers aberrant salience and related psychosis phenotype
轻柔的曲调调教出一种新奇的长期威胁回避行为	Aranda, M. L.	PDF	N/A	Light tunes a novel long-term threat avoidance behavior
LGI1自身抗体对人类CA3锥体神经元的功能影响	Monni, L.	PDF	N/A	The functional impact of LGI1 autoantibodies on human CA3 pyramidal neurons
减少叶酸载体1（RFC1/Slc19a1）抑制加剧成年小鼠实验性缺血性卒中中的血脑屏障破坏	Gurler, G.	PDF	N/A	Reduced Folate Carrier 1 (RFC1/Slc19a1) Suppression Exacerbates Blood-Brain Barrier Breakdown in Experimental Ischemic Stroke in Adult Mice
微扫视强烈地调节但并不引起空间注意的N2pc脑电标记	Liu, B.	PDF	N/A	Microsaccades strongly modulate but do not cause the N2pc EEG marker of spatial attention
酒精依赖小鼠中丘脑背内侧核的遗传和功能适应以及酒精偏向性信号传导	Martin, J. C.	PDF	N/A	Genetic and functional adaptations and alcohol-biased signaling in the mediodorsal thalamus of alcohol dependent mice
基于结构的莱姆病亚单位疫苗设计机制性见解	Brangulis, K.	PDF	N/A	Mechanistic insights into structure-based design of a Lyme disease subunit vaccine
被边缘案例所迷惑：当前方法能否通过机器学习实现对T细胞特异性的准确预测？	Culka, M.	PDF	N/A	Tricked by Edge Cases: Can Current Approaches Lead to Accurate Prediction of T-Cell Specificity with Machine Learning?
小鼠植入前发育过程中mRNA翻译的时空动态和选择性	Jiang, Z.	PDF	N/A	Spatiotemporal dynamics and selectivity of mRNA translation during mouse pre-implantation development
调整选择压力的空间分布以抑制抗性的出现	Tunstall, T.	PDF	N/A	Tuning Spatial Distributions of Selection Pressure to Suppress Emergence of Resistance
粉蚧的多样化是由新共生体的获得引发的，随后在寄主植物上发生了适应性辐射。	Choi, J.	PDF	N/A	The diversification of mealybugs was triggered by new symbiont acquisitions and followed by adaptive radiations on host plants
内皮细胞的硬度和类型驱动了生物力学诱导的跨细胞孔隙的形成	Siadat, S. M.	PDF	N/A	Endothelial cell stiffness and type drive the formation of biomechanically-induced transcellular pores
Genular：一个通过单细胞基因表达和多领域生物数据定义细胞身份和功能的综合平台	Tomic, I.	PDF	N/A	Genular: An Integrated Platform for Defining Cellular Identity and Function through Single-Cell Gene Expression and Multi-Domain Biological Data
DNA挂架：表面自由单分子印迹平台	Seol, J.	PDF	N/A	DNA Hanger: Surface Free Single-Molecule Blotting Platform
单细胞蛋白质组学和转录组学表征揭示了耐药性前列腺癌细胞的分子特征与形态变化之间的关联	Woo, J.	PDF	N/A	Single-Cell Proteomic and Transcriptomic Characterization of Drug-Resistant Prostate Cancer Cells Reveals Molecular Signatures Associated with Morphological Changes
SPP1+肿瘤相关巨噬细胞通过与肿瘤微环境的相互作用诱导鼻咽癌的放疗抵抗	Zhang, W.	PDF	N/A	SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironment
线粒体伴侣蛋白TRAP1的点突变会影响其功能和促肿瘤活性。	Laquatra, C.	PDF	N/A	Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity.
整合应激反应途径在肺癌中对多个免疫检查点的协调性转录调控	Thomas-Jardin, S.	PDF	N/A	Coordinated translational control of multiple immune checkpoints by the integrated stress response pathway in lung cancer
膳食纤维调节巨噬细胞活性在结直肠癌结肠细胞-微生物相互作用微流控模型中	Penarete-Acosta, D.	PDF	N/A	Dietary Fiber Modulates Macrophage Activity in a Microfluidic Model of Colonocyte-Microbiota Interactions in Colorectal Cancer
激素治疗前局部前列腺癌中上皮功能状态和成纤维细胞表型的分析	Apostolov, E.	PDF	N/A	Profiling of epithelial functional states and fibroblast phenotypes in hormone therapy-naive localised prostate cancer
热中性环境对小鼠MASLD严重程度、肝基因表达及β3-肾上腺素能刺激下BAT激活的影响	Martin, C. M.	PDF	N/A	Effect of thermoneutral housing on MASLD severity, hepatic gene expression, and BAT activation during beta3-adrenergic stimulation in mice
改变AP-1、RUNX和EGR的染色质动力学驱动纤维化肺病	Valenzi, E.	PDF	N/A	Altered AP-1, RUNX, and EGR chromatin dynamics drive fibrotic lung disease
抗PTHrP阻断限制了CD8+ T细胞在抗癌免疫疗法中的衰竭	Moes, B.	PDF	N/A	Anti-PTHrP blockade limits CD8+ T-cell exhaustion in anti-cancer immunotherapy
通过抗体语言模型优先掩盖非模板区域进行聚焦学习	Ng, K.	PDF	N/A	Focused learning by antibody language models using preferential masking of non-templated regions
糖尿病-结核病共病特征为Ⅱ型干扰素减少和Th17反应增强。	Chaudhary, S.	PDF	N/A	Diabetes-Tuberculosis Comorbidity Characterized by Reduced Type-II Interferon and Elevated Th17 Responses.
破坏G3BP1应激颗粒宿主蛋白与核衣壳（NTD-N）蛋白之间的分子相互作用会阻碍SARS-CoV-2病毒的复制。	Dhaka, P.	PDF	N/A	Disruption of molecular interactions between G3BP1 stress granule host protein and nucleocapsid (NTD-N) protein impedes SARS-CoV-2 virus replication
Oatk：一种用于复杂植物细胞器基因组从头组装的工具	Zhou, C.	PDF	N/A	Oatk: a de novo assembly tool for complex plant organelle genomes
PhenoScreen：一种基于双空间对比学习框架的表型筛选方法，通过将化学扰动与细胞形态联系起来	Wang, S.	PDF	N/A	PhenoScreen: A Dual-Space Contrastive Learning Framework-based Phenotypic Screening Method by Linking Chemical Perturbations to Cellular Morphology
内在无序的Qβ衣壳蛋白与含发夹RNA形成多相RNP颗粒	Granik, N.	PDF	N/A	Formation of polyphasic RNP granules by intrinsically disordered Qβ coat proteins and hairpin-containing RNA
多巴胺调控秀丽隐杆线虫对锰诱导的多巴胺能神经毒性的敏感性。	Raj, V.	PDF	N/A	Dopamine controls the Sensitivity to Manganese induced Dopaminergic neurotoxicity in Caenorhabditis elegans
棕色脂肪组织产热节律是由视交叉上核驱动的，与脂肪细胞时钟无关。	Paschos, G. K.	PDF	N/A	Brown adipose tissue thermogenesis rhythms are driven by the SCN independent of adipocyte clocks
通过免疫信息学分析进行的多表位疫苗的计算机设计，用于对抗蜱传脑炎病毒	Wang, B.	PDF	N/A	In silico design of a multi-epitope vaccine against tick-borne encephalitis virus via immunoinformatic analysis
对来自全球多源的克雷伯氏菌变种菌株进行基因组分析，揭示了与人类感染相关的适应性特征。	Wang, J.	PDF	N/A	Genome Analyses of A Worldwide Multisource Collection of Klebsiella variicola Reveal Adaptation Relevant for Human Infection
剪接因子激酶，即SR蛋白激酶1（SRPK1），对于人乳头瘤病毒生命周期的后期事件至关重要。	Faizo, A. A. A.	PDF	N/A	The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle.
CRISPR技术对基因表达的调控，决定了微生物甲烷的同位素组成。	Gropp, J.	PDF	N/A	CRISPR-enabled control of gene expression sets the isotopic composition of microbial methane
Tad菌毛ATP酶CpaF中的协调构象变化促进了催化旋转机制	Yen, I. Y.	PDF	N/A	Coordinated conformational changes in the Tad pilus ATPase CpaF facilitate a rotary mechanism of catalysis
复杂系统建模揭示，草酸盐稳态是由多种草酸盐降解细菌驱动的。	Mukherjee, S. D.	PDF	N/A	Complex system modelling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteria
在生命周期中，牛奶草虫Oncopeltus fasciatus的种内微生物群动态变化	Larner, W.	PDF	N/A	Intraspecific microbiome dynamics across the life cycle of the milkweed bug Oncopeltus fasciatus
通过哺乳动物乙型肝炎病毒X蛋白实现的保守但差异化的Smc5/6复合物降解	Shofa, M.	PDF	N/A	Conserved yet Divergent Smc5/6 Complex Degradation by Mammalian Hepatitis B Virus X Protein
通过哺乳动物乙型肝炎病毒X蛋白实现的保守但分化的Smc5/6复合物降解	Shofa, M.	PDF	N/A	Conserved yet Divergent Smc5/6 Complex Degradation by Mammalian Hepatitis B Virus X Proteins
伯氏疏螺旋体在培养的静止期会失去重要的遗传元件和细胞增殖潜力，但在蜱虫媒介中则不会。	Zhang, J.	PDF	N/A	Borrelia burgdorferi loses essential genetic elements and cell proliferative potential during stationary phase in culture but not in the tick vector.
通过增加槲皮素（一种黄酮类化合物）的生物利用度，诱导产生一种协同的抗肥胖效果，这一过程由一种植物乳杆菌（L. plantarum）菌株实现。	Kang, Y.-G.	PDF	N/A	Inducing a synergistic anti-obesity effect by increasing the bioavailability of the flavonoid rutin with a L. plantarum species
前列腺特异性膜受体PPAP通过FimH结合促进大肠杆菌入侵前列腺腔细胞	Guedes, M.	PDF	N/A	Prostate-specific membrane receptor PPAP facilitates E. coli invasion of luminal prostate cells via FimH binding
转录因子Sfp1与NuA4复合体在应对营养物质可利用性方面的功能性相互作用	Xu, K.	PDF	N/A	Functional interaction between transcription factor Sfp1 and the NuA4 complex in response to nutrient availability
一种从纯化到冻干递送的环状RNA治疗完整方案，采用新型可离子化脂质	Broset, E.	PDF	N/A	A complete approach for circRNA therapeutics from purification to lyophilized delivery using novel ionizable lipids
天然产物生物合成中假定末端酰胺化域的结构	Rankin, M. R.	PDF	N/A	Structure of a Putative Terminal Amidation Domain in Natural Product Biosynthesis
可溶性鸟苷酸环化酶（NO受体）通过其转亚硝基化活性调节内皮依赖性血管舒张。	Younis, W.	PDF	N/A	Soluble guanylyl cyclase, the NO-receptor, regulates endothelium-dependent vascular relaxation via its transnitrosation activity.
唤醒原初编辑技术：精准工程改造益生菌大肠杆菌Nissle 1917	Chen, P.-R.	PDF	N/A	Awakening prime editing for precision engineering of probiotic Escherichia coli Nissle 1917
转录调控和位点特异性生物化学的组合效应器靶向（COMET）	Wilson, C. M.	PDF	N/A	Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry
使用大型语言模型操作无细胞生物铸造厂	Herisson, J.	PDF	N/A	Operate a Cell-Free Biofoundry using Large Language Models
从微RNA表达数据中定量设计细胞类型特异性mRNA稳定性	Oesinghaus, L.	PDF	N/A	Quantitative design of cell type-specific mRNA stability from microRNA expression data
运动细菌群体中空间模式转变的机制	Saulnier, J.-B.	PDF	N/A	The mechanism of spatial pattern transition in motile bacterial collectives
跨灵长类基因组筛选包膜基因揭示内源性逆转录病毒的进化和多样性模式	Chabukswar, S.	PDF	N/A	Screening Envelope Genes Across Primate Genomes Reveals Evolution and Diversity Patterns of Endogenous Retroviruses
迈向完整的噬菌体尾部纤维结构图谱。	Klein-Sousa, V.	PDF	N/A	Towards a complete phage tail fiber structure atlas.
蓝细菌辅因子非依赖型磷酸甘油酸变位酶的结构元件，介导PirC调控	Orthwein, T.	PDF	N/A	Structural elements of cyanobacterial co-factor-independent phosphoglycerate mutase that mediate regulation by PirC
铜绿假单胞菌抵抗VI型分泌系统攻击的机制	Tejada-Arranz, A.	PDF	N/A	Mechanisms of P. aeruginosa resistance to Type VI Secretion System attacks
利用鸡胚绒毛尿囊膜模型评估肿瘤定植沙门氏菌株	Kenney, L. J.	PDF	N/A	Evaluation of Tumor-colonizing Salmonella Strains using the Chick Chorioallantoic Membrane Model
单细胞代谢动力学的回溯分析可预测细菌在人体巨噬细胞中的复制	Drame, M.	PDF	N/A	Backtracking Metabolic Dynamics in Single Cells Predicts Bacterial Replication in Human Macrophages
NACHO介导的五聚配体门控离子通道组装机制	Hooda, Y.	PDF	N/A	Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels
动态RNA结合与无义介导的mRNA降解因子UPF2的展开	Szeto, J.-Y. A.	PDF	N/A	Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2
邻近相互作用组分析揭示了IRE1a经典信号通路的新调控因子	Le Goupil, S.	PDF	N/A	Proximity Interactome analyses unveil novel regulators of IRE1a canonical signaling
Neuroligin 3突显了果蝇社交间隔中的性别二态性回路	Robinson, J. W.	PDF	N/A	Neuroligin 3 highlights sexually dimorphic circuitry in Drosophila social spacing
# BioRxiv 2024-10-27 Papers

标题	作者	PDF链接	代码仓库	Title
慢振荡-纺锤波耦合预测基于序列的语言学习	Cross, Z. R.	PDF	N/A	Slow oscillation-spindle coupling predicts sequence-based language learning
周期环境中的共存	Scott, A. M.	PDF	N/A	Coexistence in Periodic Environments
通过AAV外显子测序的CRISPR筛选（CrAAVe-seq）是一种高度可扩展的细胞类型特异性体内筛选平台。	Ramani, B.	PDF	N/A	CRISPR screening by AAV episome-sequencing (CrAAVe-seq) is a highly scalable cell type-specific in vivo screening platform
在巩固过程中，部分多巴胺能神经元的活动短暂中断，会通过破坏睡眠来损害长期记忆。	Yan, L.	PDF	N/A	Brief disruption of activity in a subset of dopaminergic neurons during consolidation impairs long-term memory by fragmenting sleep
ExploreTurns：一种用于探索、分析和分类蛋白质中beta转角和结构化环的网络工具；应用于beta凸起环、Schell曼环、Asx螺旋帽、beta发夹及其他氢键连接基序	Newell, N. E.	PDF	N/A	ExploreTurns: A web tool for the exploration, analysis, and classification of beta turns and structured loops in proteins; application to beta-bulge and Schellman loops, Asx helix caps, beta hairpins and other hydrogen-bonded motifs
非人类灵长类动物中决策与运动相互作用但解耦控制的证据	Saleri, C.	PDF	N/A	Evidence for interacting but decoupled controls of decisions and movements in non-human primates
人道主义背景下无性繁殖作物面临的病原体和害虫风险：为喀麦隆和埃塞俄比亚制定国家植物健康风险分析	Mouafo-Tchinda, R.	PDF	N/A	Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Towards a national plant health risk analysis for Cameroon and Ethiopia
Dravet综合征Scn1a+/-小鼠的神经发育缺陷：靶向GABA开关可挽救行为功能障碍，但不能改善癫痫发作和死亡率。	Pizzamiglio, L.	PDF	N/A	Neurodevelopmental defects in Dravet syndrome Scn1a+/- mice: targeting GABA-switch rescues behavioral dysfunctions but not seizures and mortality.
3DCellComposer - 一种利用2D细胞分割方法进行3D细胞分割的多功能管道	Chen, H.	PDF	N/A	3DCellComposer - A Versatile Pipeline Utilizing 2D Cell Segmentation Methods for 3D Cell Segmentation
婴儿脑电图中眼球运动伪迹的校正	Srishyla, D.	PDF	N/A	Eye-movement artifact correction in infant EEG
从背外侧前额叶皮层的转录组和表观基因组数据推断阿尔茨海默病女性患者的潜在多重疾病进展途径	Honda, K.	PDF	N/A	Potential multiple disease progression pathways in female patients with Alzheimer's disease inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex
利用生成式人工智能方法推进多器官毒性评估的跨器官转录组学研究	Li, T.	PDF	N/A	Bridging Organ Transcriptomics for Advancing Multiple Organ Toxicity Assessment with a Generative AI Approach
MGPfactXMBD：一种基于模型的分解方法，用于单细胞RNA数据，揭示了细胞命运决定背后的分叉转录模块	Ren, J.	PDF	N/A	MGPfactXMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination
杀婴行为是由对后代位置的不熟悉所驱动的，并与模仿毒蛙中的雄激素变化相关联。	Lewis, A. R.	PDF	N/A	Infanticide is driven by unfamiliarity with offspring location and associated with androgenic shifts in mimic poison frogs
鲁迪拉介导的微管稳定性调控在小鼠血管发育过程中TGFβ信号传导	Joshi, D.	PDF	N/A	Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development
优先处理工作记忆资源取决于前额叶皮层	Hallenbeck, G. E.	PDF	N/A	Prioritizing working memory resources depends on prefrontal cortex
寄生虫释放的敌对力量在入侵的非洲无花果蝇（Zaprionus indianus）中是情境依赖的。	Walsh-Antzak, C. R.	PDF	N/A	Strength of enemy release from parasitoids is context-dependent in the invasive African Fig Fly, Zaprionus indianus
禽源沙门氏菌肠炎沙门氏菌血清型鸡白痢向地方性转变的过程中伴随着局部抗性组和移动组的相互作用。	Jia, C.	PDF	N/A	Avian-specific Salmonella enterica Serovar Gallinarum transition to endemicity is accompanied by localized resistome and mobilome interaction
长寿的软骨祖细胞由胎儿肢体的Gli1+细胞产生，并在软骨中的镶嵌细胞周期停滞时得到补充。	Qu, X.	PDF	N/A	Long-lived chondroprogenitors are generated by fetal-limb Gli1+ cells and are replenished upon mosaic cell-cycle arrest in the cartilage
全原子连续恒定pH分子动力学的力场限制	Peeples, C.	PDF	N/A	Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics
人类4D核组结构与功能的综合视角	The 4D Nucleome Consortium,	PDF	N/A	An integrated view of the structure and function of the human 4D nucleome
氯胺酮通过在小鼠中表达钙离子通透性AMPA受体来逆转慢性应激引起的行为变化。	Flowers, J. C.	PDF	N/A	Ketamine reverses chronic stress-induced behavioral changes via the expression of Ca2+-permeable AMPA receptors in mice
免疫-病原体共进化中的信息处理适应性效率	Bellamy, Q. N.	PDF	N/A	Adaptive efficiency of information processing in immune-pathogen co-evolution
自由觅食的猕猴在模糊地形中重视信息	Shahidi, N.	PDF	N/A	Freely foraging macaques value information in ambiguous terrains
单个癌细胞中多种ecDNA类型的维持	Scanu, E.	PDF	N/A	The maintenance of multiple ecDNA types in single cancer cells
前脑岛中的多巴胺传递塑造了焦虑的神经编码	COUDERC, Y.	PDF	N/A	Dopamine transmission in the anterior insula shapes the neural coding of anxiety
停留时间对视觉和被动导入运动情境效应的影响	Alvarez-Hidalgo, L.	PDF	N/A	The impact of dwell time on the contextual effect of visual and passive lead-in movements
抑制RNA调节因子HuR可有效缓解脊髓损伤，通过强力抑制损伤后的神经炎症。	Husain, M. A.	PDF	N/A	Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation
后顶叶皮层介导由稀有性引发的决策偏差及不确定性下的学习	Sheng, W.	PDF	N/A	Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty
UBA5抑制剂的鉴定与表征	Singh, V.	PDF	N/A	Identification and characterization of UBA5 inhibitors
计算识别空间转录组学数据中的迁移T细胞	Zhong, L.	PDF	N/A	Computational Identification of Migrating T cells in Spatial Transcriptomics Data
基于特征的注意在人类皮层下核团功能分区中的空间全局效应	Lin, W.	PDF	N/A	Spatially global effects of feature-based attention in functional subdivisions of human subcortical nuclei
通过祖先X-Y染色体基因对Kdm5c-Kdm5d调控性别偏向基因表达	Malcore, R. M.	PDF	N/A	Regulation of Sex-biased Gene Expression by the Ancestral X-Y Chromosomal Gene Pair Kdm5c-Kdm5d
非洲起源的单体型对APOEϵ4携带者的阿尔茨海默病具有保护作用：探索潜在机制	Bertholim-Nasciben, L.	PDF	N/A	African origin haplotype protective for Alzheimer's disease in APOEϵ4 carriers: exploring potential mechanisms
CD90识别出具有不同激活和静息维持模式的肌肉干细胞的不同亚群。	Kheir, E.	PDF	N/A	CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance
景天酸代谢在CAM植物Kalanchoë laxiflora中的蛋白质水平调控	Schiller, K.	PDF	N/A	Regulation of Crassulacean Acid Metabolism at the protein level in the CAM plant Kalanchoë laxiflora
DNA甲基化年龄生物标志物具有响应性：来自51项人类长寿干预研究的见解	Sehgal, R.	PDF	N/A	DNAm aging biomarkers are responsive: Insights from 51 longevity interventional studies in humans
室旁核中的Apelin-13通过室旁核的V1a受体和孤束核的GABAA受体γ2保护大鼠心肌免受缺血损伤。	yan, w.	PDF	N/A	Apelin-13 in the paraventricular nucleus protects myocardium from ischemia via V1a receptor of the paraventricular nucleus and GABAA receptor γ2 of the nucleus tractus solitarii in rats
多发性硬化脊髓中的异常铁沉积与神经退行性变有关	Pisa, M.	PDF	N/A	Aberrant iron deposition in the multiple sclerosis spinal cord relates to neurodegeneration
训练刺激的复杂特性影响深度网络模型中大脑视觉皮层的对齐	Torabian, P.	PDF	N/A	Complex Properties of Training Stimuli Affect Brain Alignment in a Deep Network Model of Mouse Visual Cortex
脂质氢同位素组成主要反映了模式古菌Sulfolobus acidocaldarius的生长水。	Harris, C. M.	PDF	N/A	Lipid hydrogen isotope compositions primarily reflect growth water in the model archaeon Sulfolobus acidocaldarius
HIV-1包膜糖蛋白原体的化学计量学及其稳定或破坏预触发构象的变化	Zhang, Z.	PDF	N/A	Stoichiometry of HIV-1 Envelope Glycoprotein Protomers with Changes That Stabilize or Destabilize the Pretriggered Conformation
NLGN3通过激活Gαi1/3-Akt通路促进心肌梗死中的血管生成	qiao, s.	PDF	N/A	NLGN3 contributes to angiogenesis in myocardial infarction via activation of the Gαi1/3-Akt Pathway
旁观者碱基编辑干扰了莱伯先天性黑蒙视觉功能的恢复	Lee, S.-H.	PDF	N/A	Bystander base editing interferes with visual function restoration in Leber congenital amaurosis
一种新型雄性附腺肽降低了褐飞虱雌性交配后的接受性	Zhang, Y.-J.	PDF	N/A	A novel male accessory gland peptide reduces female post-mating receptivity in the brown planthopper
一夜部分睡眠剥夺对血管周围空间体积分数的影响：来自斯德哥尔摩困倦大脑研究的发现	Custer, R. M.	PDF	N/A	Effects of one-night partial sleep deprivation on perivascular space volume fraction: Findings from the Stockholm Sleepy Brain Study
皮层6b层介导了与状态相关的大脑活动变化，以及食欲素对觉醒和睡眠的影响。	Meijer, E. J.	PDF	N/A	Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep
低剂量的A型和B型肉毒杆菌神经毒素有利于沙门氏菌和志贺氏菌的感染，而不会引起肉毒中毒的松弛性麻痹。	Fabris, F.	PDF	N/A	Low Intestinal Doses of Botulinum Neurotoxins types A and B favour infection by Salmonella and Shigella without the flaccid paralysis of botulism
斑马鱼中个体保守神经元微外显子的表型影响及其主调控因子	Lopez-Blanch, L.	PDF	N/A	Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish
Foxi1通过转录和表观遗传机制调控粘液纤毛发育和离子细胞分化的多个步骤	Bowden, S.	PDF	N/A	Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms
NOTCH1驱动肝细胞癌的肿瘤可塑性和转移	Lindblad, K. E.	PDF	N/A	NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma
一种结合计算模型，用于模拟癌症球体生长，涉及核糖诱导的胶原蛋白硬化	Botticelli, M.	PDF	N/A	A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening
特定领域的模式重用在灵长类大脑中支持灵活的学习	Tian, K.	PDF	N/A	Domain-specific Schema Reuse Supports Flexible Learning to Learn in Primate Brain
分泌型Clever-1调节T细胞反应并影响癌症免疫治疗效果	Prince, S.	PDF	N/A	Secreted Clever-1 Modulates T Cell Responses and Impacts Cancer Immunotherapy Efficacy
马达聚类增强驱动囊泡运输	Jiang, R.	PDF	N/A	Motor Clustering Enhances Kinesin-driven Vesicle Transport
利用人工智能自动化检测和量化染色体外DNA（ecDNA）以解码药物反应	Goble, K.	PDF	N/A	Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses
探索以丙酮酸为唯一碳源的细菌培养基的生化环境，用于核磁共振研究	Dag, C.	PDF	N/A	Exploring the Biochemical Landscape of Bacterial Medium with Pyruvate as the Exclusive Carbon Source for NMR Studies
优化复杂RNA系统的即时概率增强采样：采样H型假结的自由能表面	Malekzadeh, K.	PDF	N/A	Optimizing On-the-Fly Probability Enhanced Sampling for Complex RNA Systems: Sampling Free Energy Surfaces of an H-Type Pseudoknot
生态上截然不同的微生物群落降解有机物一致地促进植物生长	Lee, B.	PDF	N/A	Degradation of organic matter by ecologically distinct microbiomes uniformly promotes plant growth
果糖激活了链球菌突变体中与甲基乙二醛和过氧化氢共享的应激反应	Walker, A. R.	PDF	N/A	FRUCTOSE ACTIVATES A STRESS RESPONSE SHARED BY METHYLGLYOXAL AND HYDROGEN PEROXIDE IN STREPTOCOCCUS MUTANS
密螺旋体牙龈卟啉单胞菌穿梭质粒中蛋白质表达的功能表征与优化	Goetting-Minesky, M. P.	PDF	N/A	Functional characterization and optimization of protein expression in Treponema denticola shuttle plasmids
鲍曼不动杆菌的防御体系揭示了根据其先天防御系统和噬菌体特征划分的两个基因组群体。	Moreno-Rodriguez, A.	PDF	N/A	The defensome of Acinetobacter baumannii reveals two genome groups according to their innate defense systems and phage profile
病毒进入是单核细胞中人巨细胞病毒潜伏的主要决定因素	Kitsberg, Y.	PDF	N/A	Virus Entry is a Major Determinant of HCMV Latency in Monocytes
针对ADORA-PDE10 cAMP微域：肺动脉高压的新型治疗策略	Valasarajan, C.	PDF	N/A	Targeting ADORA-PDE10 cAMP Microdomain: A Novel Therapeutic Approach for Pulmonary Hypertension
比较元转录组学揭示了浮游动物对生活环境中营养异质性的生理反应	Nuruddin, M. F.	PDF	N/A	Comparative meta transcriptomics uncovers the physiological responses of zooplankton to nutrient heterogeneity in their living environment
整合的肝铁死亡基因特征决定了铁死亡的致病特征	Matsumoto, T.	PDF	N/A	Integrated hepatic ferroptosis gene signature dictates pathogenic features of ferroptosis
细菌接种可调控珊瑚的表观基因组	Barno, A. R.	PDF	N/A	Bacterial inoculation manipulates the coral epigenome
利用16S纳米孔测序增强海底生态状态预测	Philip, M.	PDF	N/A	Enhanced Prediction of Seafloor Ecological State Using 16S Nanopore Sequencing
飞行哺乳动物Rhinolophus hipposideros的配子散布几何结构	Brazier, T.	PDF	N/A	The geometry of gametic dispersal in a flying mammal, Rhinolophus hipposideros
伯氏疏螺旋体感染的肩突硬蜱中的表观遗传反应：常染色质组蛋白赖氨酸甲基转移酶2的过表达及DNA甲基化无变化	MacIntosh, G. H.	PDF	N/A	Epigenetic responses in Borrelia-infected Ixodes scapularis ticks: Over-expression of euchromatic histone lysine methyltransferase 2 and no change in DNA methylation
低覆盖率测序工作流程在茄子精准基因分型中的基准测试	Baraja-Fonseca, V.	PDF	N/A	Benchmarking of Low Coverage Sequencing Workflows for Precision Genotyping in Eggplant
六倍体燕麦的泛基因组和泛转录组	Avni, R.	PDF	N/A	A pangenome and pantranscriptome of hexaploid oat
巨型鳞翅目昆虫古共生体中加速的假基因化	Choi, J.	PDF	N/A	Accelerated pseudogenization in ancient endosymbionts of giant scale insects
环状RNA AEBP2：树突状细胞发育中的新型调控因子	Zhou, Q.	PDF	N/A	Circular RNA AEBP2: A novel regulator in dendritic cell development
利用拓扑机器学习识别靶向细菌丙酸代谢的分子化合物	Tola, A.	PDF	N/A	Identification of Molecular Compounds Targeting Bacterial Propionate Metabolism with Topological Machine Learning
可以利用mTOR-Tfeb-Fabp7a信号轴来改善成年斑马鱼中的bag3心肌病	Ding, Y.	PDF	N/A	An mTOR-Tfeb-Fabp7a signaling axis can be harnessed to ameliorate bag3 cardiomyopathy in adult zebrafish
剖析转座元件对间期染色体结构的贡献	Shi, L.	PDF	N/A	Dissecting the Contribution of Transposable Elements to Interphase Chromosome Structure
翻译：翻译后修饰调控孤儿受体GPR52的固有信号偏倚	Zhang, B.	PDF	N/A	Post-translational modifications orchestrate the intrinsic signaling bias of orphan receptor GPR52
去氨甲酰化和未去氨甲酰化的eIF5A异构体在胰腺发育和功能模型中表现出不同的作用	Anderson, C. M.	PDF	N/A	Hypusinated and unhypusinated isoforms of eIF5A exert distinct effects in models of pancreas development and function
PXGS：一种基于Dscam互斥剪接的多基因表达系统	Yu, R. Y.	PDF	N/A	PXGS: a Poly-Transgene Expression System based on Mutually Exclusive Splicing of Dscam
基因组范围内遗传扰动的相分离景观	Heidenreich, M.	PDF	N/A	The phase separation landscape of genome-wide genetic perturbations
肌动蛋白调节因子的时空协调作用在细胞融合过程中产生侵袭性突起	Lu, Y.	PDF	N/A	Spatiotemporal coordination of actin regulators generates invasive protrusions in cell-cell fusion
IGF2通过介导Hippo信号通路来控制肝脏大小	Zhong, Z.	PDF	N/A	IGF2 mediates Hippo signaling to control liver size
全面蛋白质组学表征高尔基体内部运输中间体	Sumya, F. T.	PDF	N/A	Comprehensive Proteomic Characterization of Intra-Golgi Trafficking Intermediates
线粒体自噬调节在秀丽隐杆线虫（C. elegans）的uaDf5动物模型中，能够缓解单一大规模线粒体DNA缺失（SLSMD）疾病的症状。	Mendel, R. M.	PDF	N/A	Mitophagy modulation rescues single large-scale mitochondrial DNA deletion (SLSMD) disease symptoms in the C. elegans uaDf5 animal model.
通过表型药物筛选和药物设计开发新型黄酮类衰老细胞清除剂	Zhang, L. J.	PDF	N/A	Development of novel flavonoid senolytics through phenotypic drug screening and drug design
在受控流动条件下对芯片器官进行系统标准化：以Caki-1和A549细胞系为例的应用案例	Balsa-Diaz, A.	PDF	N/A	Systematic standardization of organ-on-a-chip under controlled flow conditions: use case with Caki-1 and A549 cell lines
# BioRxiv 2024-10-26 Papers

标题	作者	PDF链接	代码仓库	Title
脑岛和颞上沟在社交决策中对人际内疚感和责任感的贡献	Gaedeke, M.	PDF	N/A	Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions
一项关于拉尔氏菌复合体已知全球分布和宿主范围的元分析	Lowe-Power, T.	PDF	N/A	A Meta-analysis of the known Global Distribution and Host Range of the Ralstonia Species Complex
系统性降钙素基因相关肽（CGRP）可修饰听觉和前庭终器的电位，并增加感觉超敏性。	Rahman, S. M.	PDF	N/A	Systemic Calcitonin Gene-Related Peptide (CGRP) modifies auditory and vestibular end organ electrical potentials, and increases sensory hypersensitivities
利用果蝇探究多细胞生物多聚磷酸盐生物学：揭示新颖且保守的多聚磷酸盐功能	Sarkar, S.	PDF	N/A	Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions
在鼠类成纤维细胞中，微管的全球排列和局部曲率对于波形蛋白和肌动蛋白的扰动具有较强的稳健性。	Blob, A.	PDF	N/A	Global alignment and local curvature of microtubules in mouse fibroblasts are robust against perturbations of vimentin and actin
巨噬细胞特异性脂质纳米颗粒疗法通过巨噬细胞-上皮相互作用阻断肺部机械敏感性免疫	Mthunzi, L.	PDF	N/A	Macrophage-specific lipid nanoparticle therapy blocks the lungs mechanosensitive immunity due to macrophage-epithelial interactions
大型生物银行队列中随访数据的分析：方法学综述	Kolde, A.	PDF	N/A	Analysis of follow-up data in large biobank cohorts: a review of methodology
在诱导多能干细胞衍生的神经元中进行的CRISPR筛选揭示了tau蛋白稳态的原理	Samelson, A. J.	PDF	N/A	CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
邻域内相关性在植物间相互作用中的作用：对黑杨高度生长和锈病损害的影响	Tiret, M.	PDF	N/A	The role of relatedness within a neighborhood in plant-to-plant interaction: effect on height growth and rust damage in Populus nigra
炎症小体主要限制了胞质内沙门氏菌在人类巨噬细胞中的复制	Egan, M. S.	PDF	N/A	Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages
火烈鸟参与多种细胞竞争模式	Bosch, P. S.	PDF	N/A	Flamingo participates in multiple models of cell competition
ATP释放的缝隙连接通道受溶血磷脂调控	Henze, E.	PDF	N/A	ATP-release pannexin channels are gated by lysophospholipids
扩张型心肌病相关RNA结合基序蛋白20调控神经元中的长前体mRNA	Di Bartolomei, G.	PDF	N/A	Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons
休息期间的记忆巩固会在认知地图中形成捷径	Shearer, C. M.	PDF	N/A	Memory consolidation during rest forms shortcuts in a cognitive map
ABC转运蛋白BmrA的构象变化依赖于膜曲率	Damm, A.	PDF	N/A	Conformational changes of the ABC Transporter BmrA Depend on Membrane Curvature
多样执行功能全基因组关联研究的基因组SEM模型提高了基因发现	Perry, L. C.	PDF	N/A	GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene Discovery
克服“饥饱”效应：全基因组关联研究中的改进交互测试	Zhou, H.	PDF	N/A	Overcoming the "feast or famine" effect: improved interaction testing in genome-wide association studies
慢性血栓栓塞性肺动脉高压中肺血管树的内皮特征：独特还是共有的方面？	Verhaegen, J.	PDF	N/A	Endothelial features along the pulmonary vascular tree in chronic thromboembolic pulmonary hypertension: distinctive or shared facets?
环节动物幼虫的全身体连接组	Veraszto, C.	PDF	N/A	Whole-body connectome of a segmented annelid larva
18种人类癌症基因表达的深度分析	Qiu, W.	PDF	N/A	A deep profile of gene expression across 18 human cancers
自噬蛋白ATG14通过防止非计划性细胞焦亡的激活，在早期妊娠期间确保胚胎运输的安全进行。	POPLI, P.	PDF	N/A	The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy
角质形成细胞中Semaphorin 4A的下调反映了非皮损性银屑病的特征。	Kume, M.	PDF	N/A	Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis
Nicheformer：单细胞和空间组学的基石模型	Schaar, A. C.	PDF	N/A	Nicheformer: a foundation model for single-cell and spatial omics
在羊膜动物原肠胚形成过程中，左右组织形成之前，双侧细胞流动显示出不对称性。	Asai, R.	PDF	N/A	Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation
高加索侏儒虾虎鱼（Knipowitschia cf. caucasica）染色体水平基因组参考，这是一种新入侵莱茵河的虾虎鱼科外来物种	Schoenle, A.	PDF	N/A	Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine
评估用于非靶向代谢组学的提取溶剂，以解析南极冰岩洞中溶解有机物的成分	Mundhe, S. D.	PDF	N/A	Evaluation of extraction solvents for untargeted metabolomics to decipher the dissolved organic matter of Antarctic cryoconite holes
青蒿琥酯、EDTA和多粘菌素联合作用对MCR阴性和阳性的多粘菌素耐药沙门氏菌具有协同抗菌效果。	Zhai, Y.	PDF	N/A	Artesunate, EDTA and colistin work synergistically against MCR-negative and -positive colistin-resistant Salmonella
执行资源塑造了语言可预测性在整个成年期内的影响	Schuckart, M. M.	PDF	N/A	Executive Resources Shape the Effects of Language Predictability Across the Adult Lifespan
开放通道液滴微流控平台用于被动生成人类精子微滴	Nicholson, T. M.	PDF	N/A	Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets
在颜色不显眼的青蛙中被动积累生物碱，精炼了后天化学防御的进化范式。	Tarvin, R. D.	PDF	N/A	Passive accumulation of alkaloids in inconspicuously colored frogs refines the evolutionary paradigm of acquired chemical defenses
幅度熵用于捕捉癫痫发作期间脑动力学改变中的类嵌合体行为	Ghosh, S.	PDF	N/A	Amplitude entropy to capture chimera-like behavior in the altered brain dynamics during seizures
稀疏标注足以用于启动密集分割的训练	Thiyagarajan, V. V.	PDF	N/A	Sparse Annotation is Sufficient for Bootstrapping Dense Segmentation
优化One-Pot PURE系统中的蛋白质生产：对反应组成和表达效率的见解	Zhang, Y.	PDF	N/A	Optimizing protein production in the One-Pot PURE system: insights into reaction composition and expression efficiency
镁通过调节磷脂代谢促进细菌对抗生素的表型抗性	Li, H.	PDF	N/A	Magnesium modulates phospholipid metabolism to promote bacterial phenotypic resistance to antibiotics
TissueViewer：基于网络的多重图像查看器	van IJzendoorn, D. G. P.	PDF	N/A	TissueViewer: A Web-Based Multiplexed Image Viewer
生态进化引导的路径组学分析用于预测DCIS升级	Xiao, Y.	PDF	N/A	Eco-evolutionary Guided Pathomic Analysis to Predict DCIS Upstaging
GlyT2阳性中间神经元调控小脑-行为回路中信息传递的时间和变异性	Palacios, E. R.	PDF	N/A	GlyT2-positive interneurons regulate timing and variability of information transfer in a cerebellar-behavioural loop
“微离线收益”对运动技能学习没有益处	Das, A.	PDF	N/A	"Micro-offline gains" convey no benefit for motor skill learning
NF-κB表观遗传吸引子景观驱动乳腺癌异质性	Lopes, F. J. P.	PDF	N/A	NF-κB Epigenetic Attractor Landscape Drives Breast Cancer Heterogeneity
流感病毒感染经历会改变肺结构细胞的动态，从而在病毒再次挑战后迅速获得免疫保护。	Worrell, J. C.	PDF	N/A	Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
流感病毒感染经历会改变肺结构细胞的动态，从而在病毒再次挑战后迅速获得免疫保护。	Worrell, J. C.	PDF	N/A	Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
苏云金芽孢杆菌库尔斯塔克亚种施用对加拿大东部北方森林中非目标夜行性大蛾生物多样性的影响。	Young, J. O.	PDF	N/A	Effects of Bacillus thuringiensis subsp. kurstaki application on non-target nocturnal macromoth biodiversity in the eastern boreal forest, Canada.
巴西大西洋森林中不同土地覆盖类型的相对易燃性	Adorno, B. F.	PDF	N/A	Relative fire-proneness of land cover types in the Brazilian Atlantic Forest
链藻类NMCP类核纤层蛋白的结构多样性与分布	Kosztyo, B. S.	PDF	N/A	Structural diversity and distribution of NMCP-class nuclear lamina proteins in streptophytic algae
距离预测的神经表征精度与算术表现相关	Zhao, H.	PDF	N/A	Neural Representation Precision of Distance Predicts Arithmetic Performance
转录因子Chronophage/BCL11A/B促进肠干细胞增殖和内分泌分化	King, E. A.	PDF	N/A	The transcription factor Chronophage/BCL11A/B promotes intestinal stem cell proliferation and endocrine differentiation
人类遗传祖先、结核分枝杆菌多样性与坦桑尼亚达累斯萨拉姆市结核病严重程度的关系	Zwyer, M.	PDF	N/A	Human genetic ancestry, Mycobacterium tuberculosis diversity and tuberculosis disease severity in Dar es Salaam, Tanzania
体内抗体标记途径和荧光染料决定了标记效率、灵敏度和持久性	Hagan, N. B.	PDF	N/A	In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity
快速且准确的LSTM元建模体外TNF诱导的肿瘤抗性	Abrate, M. P.	PDF	N/A	Fast and Accurate LSTM Meta-modeling of TNF-induced Tumor Resistance In Vitro
RRx-001在实验性子宫内膜异位症小鼠模型中的临床前测试显示出有前景的治疗效果。	McIntyre, I.	PDF	N/A	Preclinical testing of RRx-001 in mouse models of experimental endometriosis reveals promising therapeutic impacts
量化面肩肱型肌营养不良症的抗DUX4疗法	Cowley, M. V.	PDF	N/A	Quantifying anti-DUX4 therapy for facioscapulohumeral muscular dystrophy
转录因子SlMYB41、SlMYB92和SlWRKY71调控番茄外皮层基因表达	Jo, L.	PDF	N/A	Transcription factors SlMYB41, SlMYB92 and SlWRKY71 regulate gene expression in tomato exodermis
识别质膜孔蛋白在质膜孔中的存在	Schladt, T. M.	PDF	N/A	Identification of nuclear pore proteins at plasmodesmata
在皮层和丘脑中，典型的突触和神经元特性的发育可以在没有小胶质细胞的情况下进行。	O'Keeffe, M.	PDF	N/A	Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus
使用Exeter Multiscope自动测量心肌细胞单层收缩	Corbett, A. D.	PDF	N/A	Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope
一种新型的小鼠前肢生物力学模型预测了在抓取运动的最优控制模拟中的肌肉活动	Gilmer, J. I.	PDF	N/A	A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements
脊髓V1中间神经元的转录组图谱揭示了En1在运动输出特定元素中的作用	Trevisan, A. J.	PDF	N/A	The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output
在斑马鱼神经杆内局部光遗传激活NMYII会导致长距离、不对称的力量传播	Crellin, H. A.	PDF	N/A	Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation
SC-MAMBA2：利用状态空间模型实现高效的单细胞超长转录组建模	Zhao, Y.	PDF	N/A	SC-MAMBA2: Leveraging State-Space Models for Efficient Single-Cell Ultra-Long Transcriptome Modeling
一项简单的措施减少了小鼠的高脂肪饮食摄入和肥胖	Barrett, M. R.	PDF	N/A	A simple action reduces high fat diet intake and obesity in mice
FIP 1.0数据集：高分辨率标注的4000个小麦地块在六年间的图像时间序列	Roth, L.	PDF	N/A	The FIP 1.0 Data Set: Highly Resolved Annotated Image Time Series of 4,000 Wheat Plots Grown in Six Years
结合扩展显微技术和邻近标记技术揭示了锥虫核孔中保守且独特的非对称功能枢纽	Gabiatti, B. P.	PDF	N/A	A combination of expansion microscopy and proximity labelling reveals conserved and unique asymmetric functional hubs at the trypanosome nuclear pore
从非靶向代谢组学数据中直接经验性地建立药物暴露记录	Zhao, H. N.	PDF	N/A	Empirically establishing drug exposure records directly from untargeted metabolomics data
星形胶质细胞的区域特化是由出生后的发育过程塑造的。	Schroeder, M. E.	PDF	N/A	Astrocyte regional specialization is shaped by postnatal development
气溶胶化合物对肺表面活性剂破坏作用的实验与建模	Barlow, H. J.	PDF	N/A	Experiments and modelling of pulmonary surfactant disruption by aerosolised compounds
B细胞表达的酶PexRAP（乙醚脂质生物合成中的中间体）促进了抗体反应和生发中心的大小。	Cho, S. H.	PDF	N/A	B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
比较系统性垂体腺苷酸环化酶激活肽（PACAP）和降钙素基因相关肽（CGRP）对小鼠运动诱导的恶心及平衡行为的影响	Rahman, S. M.	PDF	N/A	Comparing The Impact of Systemic Pituitary Adenylate-Cyclase-Activating Polypeptide (PACAP) and Calcitonin Gene-Related Peptide (CGRP) on Motion-Induced Nausea And Balance Behaviors In Mice
Bur1驱动的G1-到S期转变诱导了酵母检查点突变体对羟基脲的敏感性	da Silva, S. C. R.	PDF	N/A	Bur1-driven G1-to-S phase transition induces hydroxyurea sensitivity in yeast checkpoint mutants
周期蛋白-G相关激酶（GAK）是一种新型的有丝分裂激酶，也是弥漫性大B细胞淋巴瘤的治疗靶点。	Lightfuss, O. B.	PDF	N/A	The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma
通过完整组装揭示了小鼠亚种间端粒和着丝粒的结构多样性	Francis, B.	PDF	N/A	The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies
精神分裂症和健康个体中持续存在的深层脑部形态和不对称性的性别差异：ENIGMA-精神分裂症工作组的元分析	Cimmino, D. B.	PDF	N/A	Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group
CRB2耗竭诱导YAP信号传导并破坏足细胞的机械感应	Sun, Y.	PDF	N/A	CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。	Georgiadou, A.	PDF	N/A	Anemia and tissue hypoxia are major determinants of malarial hypelactatemia
仿生光纳米生物界面实现了多尺度生物调控	Mueller, C.	PDF	N/A	Biomimic opto-nanobiointerface enables multiscale biomodulation
用于检测纳米孔直接RNA测序中嵌合体伪影的基因组语言模型	Li, Y.	PDF	N/A	A Genomic Language Model for Chimera Artifact Detection in Nanopore Direct RNA Sequencing
停留时间对视觉和被动引入运动情境效果的影响	Alvarez-Hidalgo, L.	PDF	N/A	The impact of dwell time on the contextual effect of visual and passive lead-in movements
由光栅响应构建的编码流形在皮质视觉区域中组织了对自然场景的响应	Dyballa, L.	PDF	N/A	Encoding manifolds constructed from grating responses organize responses to natural scenes in cortical visual areas
阿尔茨海默病进展过程中情景记忆网络的功能障碍	Lattmann-Grefe, R.	PDF	N/A	Dysfunction of the episodic memory network in the Alzheimer's disease cascade
普通狨猴的拉绳行为	Bertrand, M.	PDF	N/A	String-pulling by the common marmoset
抑制RNA调节因子HuR可有效缓解脊髓损伤，通过强力抑制损伤后的神经炎症。	Husain, M. A.	PDF	N/A	Inhibition of the RNA Regulator HuR mitigates spinal cord injury by potently suppressing post-injury neuroinflammation
避孕药和激素相关功能连接组在月经周期中的特异性和普遍性	Bottenhorn, K. L.	PDF	N/A	Idiosyncrasy and generalizability of contraceptive- and hormone-related functional connectomes across the menstrual cycle
共享和独特的终身压力源特征以及大脑网络预测青少年焦虑和抑郁	Qu, Y.	PDF	N/A	Shared and unique lifetime stressor characteristics and brain networks predict adolescent anxiety and depression
结合组织病理学和机器学习的人工智能网络能够提取自闭症谱系障碍中的轴突病理。	Yazdanbakhsh, A.	PDF	N/A	Artificial intelligence networks combining histopathology and machine learning can extract axon pathology in autism spectrum disorder
一种三维免疫标记方法，结合了过氧化物酶融合的纳米抗体和荧光素标记的酪胺-葡萄糖氧化酶信号放大技术	Yamauchi, K.	PDF	N/A	A Three Dimensional Immunolabeling Method with Peroxidase-fused Nanobodies and Fluorochromized Tyramide-Glucose Oxidase Signal Amplification
解码嗅球输出：行为评估速率、同步性和呼吸相位编码	Fu, X.	PDF	N/A	Decoding Olfactory Bulb Output: A Behavioral Assessment of Rate, Synchrony, and Respiratory Phase Coding
一种新型基于菁染料的荧光染料用于神经毒性条件下和体内脑研究的靶向线粒体成像	Bi, L.	PDF	N/A	A Novel Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging in Neurotoxic Conditions and In Vivo Brain Studies
顶叶后皮质介导由稀有性引发的决策偏差及在不确定性下的学习过程。	Sheng, W.	PDF	N/A	Posterior parietal cortex mediates rarity-induced decision bias and learning under uncertainty
早期对体液稳态的干扰会改变下丘脑摄食回路的发育，并导致摄食行为的特定情境变化。	Sweet, S. R.	PDF	N/A	Early perturbations to fluid homeostasis alter development of hypothalamic feeding circuits with context-specific changes in ingestive behavior
EEG-VLM工具箱：将体素化病变映射扩展至多维脑电数据	Hardstone, R.	PDF	N/A	EEG-VLM Toolbox: Extending voxel-based lesion mapping to multi-dimensional EEG data
UBR4、LRP1 和 OPHN1 在难治性癫痫中的相互作用：利用果蝇模型研究癫痫的多基因效应	Huang, R.-N.	PDF	N/A	The Interaction of UBR4, LRP1, and OPHN1 in Refractory Epilepsy: Drosophila Model to Investigate the Oligogenic Effect on Epilepsy
产卵抑制神经元是果蝇大脑中多电路整合的潜在枢纽	Weber Langstaff, R.	PDF	N/A	The Oviposition Inhibitory Neuron is a potential hub of multi-circuit integration in the Drosophila brain
摩擦系数之外的选择：精细触觉感知依赖于摩擦不稳定性	Derkaloustian, M.	PDF	N/A	Alternatives to Friction Coefficient: Fine Touch Perception Relies on Frictional Instabilities
高精度神经反馈引导的冥想训练优化了现实世界中自我引导的冥想实践，以促进福祉。	Ganesan, S.	PDF	N/A	High-precision neurofeedback-guided meditation training optimises real-world self-guided meditation practice for well-being
在个人空间中的多感官整合可以反映睡眠和意识障碍中的意识状态	Bertoni, T.	PDF	N/A	Multisensory integration in Peripersonal Space indexes consciousness states in sleep and disorders of consciousness
显式获取的心理模式间相互关系降低认知负荷并促进小鼠和人工神经网络中新颖反应的出现。	Singh, V. P.	PDF	N/A	Explicitly Acquired Interrelations Among Mental Schema Reduces Cognitive Load and Facilitates Emergence of Novel Responses in Mice and Artificial Neural Networks.
青春期C57BL/6J小鼠在单次暴饮乙醇暴露后情境消退学习的性别差异	Cardona-Jordan, K. M.	PDF	N/A	Sex Differences in Contextual Extinction Learning After Single Binge-Like EtOH Exposure in Adolescent C57BL/6J Mice
在青光眼小鼠模型中，小胶质细胞对眼内压升高和视觉丘脑突触丢失做出反应。	Thompson, J. L.	PDF	N/A	Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucoma.
连接蛋白43介导的线粒体转移可预防顺铂诱导的感觉神经退行性变。	Owen, B.	PDF	N/A	Connexin 43 mediated mitochondrial transfer prevents cisplatin induced sensory neurodegeneration.
“迷你分析”是突触变化的不可靠报道者	Greger, I. H.	PDF	N/A	'Mini analysis' is an unreliable reporter of synaptic changes
使用-SynVesT-1-成像技术研究衰老和阿尔茨海默病中的突触密度	Giorgio, J.	PDF	N/A	Imaging synaptic density in ageing and Alzheimer's Disease with -SynVesT-1
测试测试：利用基于连接组学的预测模型揭示标准化测试和临床症状所反映的系统	Samardzija, A.	PDF	N/A	Testing the Tests: Using Connectome-Based Predictive Models to Reveal the Systems Standardized Tests and Clinical Symptoms Are Reflecting
在原条延伸期间及之后，中线模式对有丝分裂的敏感性存在差异	Zhao, Z.	PDF	N/A	Differential Sensitivity of Midline Patterning to Mitosis during and after Primitive Streak Extension
小鼠跟腱成熟过程中的单核转录组和染色质可及性分析揭示了腱干细胞/祖细胞的分子图谱	Asahara, H.	PDF	N/A	Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells
果蝇Trus，哺乳动物PDCD2L的直系同源基因，对于正常的细胞增殖、幼虫发育时序以及卵子发生是必需的。	Takada, S.	PDF	N/A	Drosophila Trus, the orthologue of mammalian PDCD2L, is required for proper cell proliferation, larval developmental timing, and oogenesis
涡虫在反复接触电离辐射后发展出辐射耐受性	Barghouth, P. G.	PDF	N/A	Planarians Develop Radiotolerance to Recurrent Ionizing Radiation Exposure
Abl激酶通过调节FGF信号传导，独立于Crk磷酸化，以防止彼得氏异常。	Wu, H.	PDF	N/A	Abl kinases regulate FGF signaling independent of Crk phosphorylation to prevent Peters anomaly
Irx3/5 定义了耳蜗的感觉域，并调节哺乳动物内耳的前庭和耳蜗感觉模式。	Liu, Y.	PDF	N/A	Irx3/5 define the cochlear sensory domain and regulate vestibular and cochlear sensory patterning in the mammalian inner ear
肺发育过程中初级纤毛和运动纤毛的时空动态变化	Spurgin, S.	PDF	N/A	Spatiotemporal dynamics of primary and motile cilia throughout lung development
子宫基质而非上皮中的PTGS2对小鼠妊娠成功至关重要	Massri, N.	PDF	N/A	Uterine stromal but not epithelial PTGS2 is critical for murine pregnancy success
塑造小鼠和沙鼠尾巴椎骨比例发育和进化的细胞和分子机制	Weber, C. J.	PDF	N/A	Cellular and molecular mechanisms that shape the development and evolution of tail vertebral proportion in mice and jerboas
早期背侧胰腺芽中Hippo信号通路组分的表征	Ahuja, N. H.	PDF	N/A	Characterization of Hippo Signaling Components in the Early Dorsal Pancreatic Bud
IntelliProfiler：一种用于分析多个动物在家庭笼中行为动态的新型分析工具	Ochi, S.	PDF	N/A	IntelliProfiler: a novel analytic tool for behavior dynamics of multiple animals in a home cage
背侧纹状体神经炎症通过破坏稳态星形胶质细胞功能导致过度目标导向行为控制	Abiero, A. R.	PDF	N/A	Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting homeostatic astrocyte function
社会经验塑造了为繁殖成功而战的策略	Gao, C.	PDF	N/A	Social Experience Shapes Fighting Strategies for Reproductive Success
持续整合航向和目标方向以引导转向	Crown, A. M.	PDF	N/A	Continuous integration of heading and goal directions guides steering
在自然视觉过程中，人类视觉皮层早期的感觉反应最好由扫视（saccade）的开始，而非注视（fixation）的开始来解释。	Amme, C.	PDF	N/A	Saccade onset, not fixation onset, best explains early sensory responses across the human visual cortex during naturalistic vision
身体游离揭示了思维的具身维度，具有独特的影响和神经特征。	Banellis, L.	PDF	N/A	Body-wandering reveals an embodied dimension of thought with distinct affective and neural signatures
奖励激发等长握持动作	Marbaker, R. M.	PDF	N/A	Reward invigorates isometric gripping actions
在模拟激活阈值时，统计方法考虑了神经元周围微观电场的畸变。	Weise, K.	PDF	N/A	Statistical method accounts for microscopic electric field distortions around neurons when simulating activation thresholds
神经系统中降钙素基因相关受体成分蛋白（RCP）的缺失可偏向于gepant拮抗作用	Rahman, S.	PDF	N/A	Loss of Calcitonin gene-related Related Receptor component protein (RCP) in nervous system can bias gepant antagonism
使用指数梯度进行类脑学习	Cornford, J.	PDF	N/A	Brain-like learning with exponentiated gradients
第三人称视角冥想调节了最小自我和心跳引发的电位	Yang, H.	PDF	N/A	Meditation in the third-person perspective modulates minimal self and heartbeat-evoked potentials
慢性激活皮质脊髓束神经元在锥体束切断术后既不能增强行为恢复，也不能促进轴突萌发。	Wang, Z.	PDF	N/A	Chronic activation of corticospinal tract neurons after pyramidotomy injury enhances neither behavioral recovery nor axonal sprouting
Ybx1引导C/EBPα和cBAF染色质重塑复合物，促进脂肪变性肝细胞中的脂肪生成基因表达。	Jordan, J. M.	PDF	N/A	Ybx1 guides C/EBPα and cBAF chromatin-remodeling complex to promote adipogenic gene expression in steatotic hepatocytes
单核细胞衍生的CXCL12引导斑马鱼血管的定向迁移	Liu, D.	PDF	N/A	Monocytes-derived cxcl12 guides a directional migration of blood vessels in zebrafish
定量解析秀丽隐杆线虫早期胚胎发育中的细胞命运	Xiong, R.	PDF	N/A	Quantitative Resolving Cell Fate in the Early Embryogenesis of Caenorhabditis elegans
三刺鱼通过面部识别来识别熟悉的个体。	SOGAWA, S.	PDF	N/A	Three-spined sticklebacks recognise familiar individuals by facial recognition
静息态功能连接在音频触觉语音训练后的变化	Ciesla, K.	PDF	N/A	Resting-state functional connectivity changes following audio-tactile speech training
外显的视觉注意在腹侧和背侧内侧前额叶皮层中调节与决策相关的信号	Shevlin, B. R. K.	PDF	N/A	Overt visual attention modulates decision-related signals in ventral and dorsal medial prefrontal cortex
Gb3三糖基化外泌体作为志贺毒素1型的新型中和剂	Mikolajczyk, K.	PDF	N/A	Gb3 trisaccharide-bearing exosomes as a novel neutralizer for Shiga toxin type 1
原核生物和噬菌体中抗病毒防御系统的基因组景观	Li, J.	PDF	N/A	Genomic landscape of antiviral defense systems in prokaryotes and phages
胚胎氧水平的变化提示了肢体起始的异时性。	Zhu, M.	PDF	N/A	Shifts in embryonic oxygen levels cue heterochrony in limb initiation
空间定量代谢组学能够识别中风后对侧皮质代谢重编程的远距离和持续性	Wang, G.	PDF	N/A	Spatial quantitative metabolomics enables identification of remote and sustained ipsilateral cortical metabolic reprogramming after stroke
拟南芥中鼠李半乳糖醛酸聚糖-I（RG-I）的深层结构分析揭示了果胶多样性的新见解	Zhang, L.	PDF	N/A	Deep structural analysis of rhamnogalacturonan-I (RG-I) in Arabidopsis reveals new insights into pectin diversity
UBA5抑制剂的鉴定与表征	Singh, V.	PDF	N/A	Identification and characterization of UBA5 inhibitors
合理设计的鼻腔微生物群落体外代谢相互作用网络	Bonillo-Lopez, L.	PDF	N/A	In vitro metabolic interaction network of a rationally designed nasal microbiota community
Malat1通过控制早期分化和对IL2的反应来调节女性Th2细胞的细胞因子表达。	Gwynne, M.	PDF	N/A	Malat1 regulates female Th2 cell cytokine expression through controlling early differentiation and response to IL2
生物相互作用塑造了拟南芥中的感染结果	Mahmoudi, M.	PDF	N/A	Biotic interactions shape infection outcomes in Arabidopsis
混合物中噬菌体的生命史特征决定了共感染的动态和效力	Khan, R.	PDF	N/A	The life history traits of phages in a cocktail determine coinfection dynamics and efficacy
三种CRISPR-Cas类型之间的交叉对话使李斯特菌seeligeri中的引发型VI-A适应成为可能	Margolis, S. R.	PDF	N/A	Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri
表达胸苷激酶的黄热病17D报告病毒有助于前药激活和感染细胞的生物正交标记	Yakass, M. B.	PDF	N/A	Thymidine kinase-expressing yellow fever 17D reporter virus facilitates prodrug activation and bioorthogonal labelling of infected cells
由tafazzin控制的线粒体心磷脂代谢能够促进铁死亡	Wohlfarter, Y.	PDF	N/A	Mitochondrial cardiolipin metabolism controlled by tafazzin enables ferroptosis
探索南大洋渔业变化机制：基于合作生产网络模型	Ward, D.	PDF	N/A	Exploring mechanisms of change in a Southern Ocean fishery with a co-produced network model
长期变暖会颠倒生态系统功能与微生物资源获取之间的关系。	Shinfuku, M. S.	PDF	N/A	Long-term warming inverts the relationship between ecosystem function and microbial resource acquisition
海藻全生物的季节性循环：多年时间序列揭示了重复的微生物变化和核心类群	Mudlaff, C. M.	PDF	N/A	Seasonal cycles in a seaweed holobiont: A multiyear time series reveals repetitive microbial shifts and core taxa
揭示不同人类免疫细胞中转座元件介导的调控景观	Du, C.	PDF	N/A	Unraveling transposable element-mediated regulatory landscape in diverse human immune cells
携带III型分泌系统2（T3SS2）和副溶血性弧菌TDH毒素的米氏弧菌在整合接合元件背景下的研究	Morgado, S.	PDF	N/A	Vibrio mimicus carrying the Type III Secretion System 2 (T3SS2) and TDH toxin of Vibrio parahaemolyticus in an integrative conjugative element context
肾缺血-再灌注损伤后细胞状态和选择性剪接的动态变化	Markiewitz, D.	PDF	N/A	Dynamics of cell states and alternative splicing following kidney ischemia-reperfusion injury
弧菌超整合子中ST热稳定肠毒素基因盒的表达模式	Fonseca, E. L.	PDF	N/A	Expression pattern of the ST heat-stable enterotoxin gene cassettes in Vibrios superintegrons
一种序列特异性的RNA乙酰化催化剂	Thalalla Gamage, S.	PDF	N/A	A sequence-specific RNA acetylation catalyst
表达人α1,4-半乳糖基转移酶的B4GALT5缺陷CHO-Lec2细胞：用于研究志贺毒素受体的糖工程细胞模型	Mikolajczyk, K.	PDF	N/A	B4GALT5-deficient CHO-Lec2 cells expressing human alpha1,4-galactosyltransferase: a glycoengineered cell model for studying Shiga toxin receptors
人类MUTYH的结构及其癌症相关变体的功能分析揭示了其辅因子簇与活性位点之间的变构网络，这对DNA修复至关重要。	Trasvina-Arenas, C. H.	PDF	N/A	Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its cluster cofactor and active site required for DNA repair
AlphaBridge：用于分析预测的大分子复合物的工具	Alvarez Salmoral, D.	PDF	N/A	AlphaBridge: tools for the analysis of predicted macromolecular complexes
通过流形再现分析进行生成模型的验证	Lazzaro, N.	PDF	N/A	Generative Models Validation via Manifold Recapitulation Analysis
在生理培养条件下以代谢为导向的化合物筛选发现了一种对未接受治疗和耐药黑色素瘤细胞具有高度抑制作用的NAMPT抑制剂。	Preis, J. R.	PDF	N/A	Metabolism-oriented compound screen in physiological culture conditions identifies a NAMPT inhibitor highly effective against drug-naive and -resistant melanoma cells
确定同时抑制核黄素代谢和MEK作为胰腺癌的新型治疗策略	Ooshio, T.	PDF	N/A	Identifying simultaneous inhibition of riboflavin metabolism and MEK as a novel therapeutic strategy for pancreatic cancer
精氨酸代谢的免疫原性转变触发了全身代谢和免疫系统的重新编程，以预防HER2阳性乳腺癌	Sharma, V.	PDF	N/A	Immunogenic shift of arginine metabolism triggers systemic metabolic and immunological reprogramming to prevent HER2+ breast cancer
计算机预测和基因分析揭示了视黄酸调节作为遗传多样性秀丽隐杆线虫中保守的长寿通路的驱动因素	Banse, S. A.	PDF	N/A	Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically-diverse Caenorhabditis nematodes
将DNA甲基化图谱与大鼠群中由β-肾上腺素能刺激引起的心脏病理联系起来	Lahue, C.	PDF	N/A	Mapping DNA Methylation to Cardiac Pathologies Induced by Beta-Adrenergic Stimulation in a Large Panel of Mice
FicD AMP化失调通过破坏胰腺内分泌稳态导致糖尿病	Casey, A. K.	PDF	N/A	Dysregulation of FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis
# BioRxiv 2024-10-25 Papers

标题	作者	PDF链接	代码仓库	Title
ADP-核糖通过重塑嘌呤和嘧啶代谢触发神经元铁死亡	Yuan, L.	PDF	N/A	ADP-ribose triggers neuronal ferroptosis by rewiring purine and pyrimidine metabolism
去泛素化抑制剂与SARS-CoV-2木瓜样蛋白酶结合的活性分析及其在鼠感染模型中的抗病毒功效	Choudhary, S.	PDF	N/A	Activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease with antiviral efficacy in murine infection model
实验微生物群落中的宏观生态模式	Shoemaker, W. R.	PDF	N/A	Macroecological patterns in experimental microbial communities
利用AlphaFold揭示hERG通道构象状态的秘密	Ngo, K.	PDF	N/A	Harnessing AlphaFold to reveal hERG channel conformational state secrets
JAK2/STAT3信号通路介导了甲基汞对小鼠星形胶质细胞神经元C8-D1A细胞系的毒性作用	Ahmed, A.	PDF	N/A	JAK2/STAT3 signaling pathway mediates methylmercury toxicity in mouse astrocyte neuronal C8-D1A cell line
皮质醇动态变化及斑马鱼幼体在反复应激下依赖于糖皮质激素受体（GR）的反馈调节	Castillo-Ramirez, L. A.	PDF	N/A	Cortisol dynamics and GR-dependent feedback regulation in zebrafish larvae exposed to repeated stress
早期生活挑战增强了斑马鱼幼体的皮质醇调节能力	Castillo-Ramirez, L. A.	PDF	N/A	Early life challenge enhances cortisol regulation in zebrafish larvae
自扩增与环状mRNA疫苗在SARS-CoV-2免疫原性与保护效力方面的比较	Singh, O. N.	PDF	N/A	Comparison of immunogenicity and protection efficacy of self-amplifying and circular mRNA vaccines for SARS-CoV-2
肩胛间棕色脂肪组织的交感神经支配并不是雄性饮食诱导肥胖大鼠中OT引发体重增加和脂肪减少的主要介质。	Edwards, M. M.	PDF	N/A	Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
EFP分析器：一款快速、准确且易于教学的程序，用于分析由诱导多能干细胞衍生的心肌细胞产生的胞外场电位	Patel, N. P.	PDF	N/A	EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes
季节性到年代际叶面积动态的通用模型	Zhou, B.	PDF	N/A	A general model for the seasonal to decadal dynamics of leaf area
全球鉴定衣藻中AGO3-RNA相互作用揭示了小RNA介导的核与叶绿体基因表达调控	Murakami, S.	PDF	N/A	Global identification of AGO3-RNA interactions in Chlamydomonas reveals the small RNA-mediated regulation of nuclear and chloroplast gene expression
利用明场显微镜进行虚拟染色，实现植物细胞结构的无标记定量分析	Ichita, M.	PDF	N/A	Virtual staining from bright-field microscopy for label-free quantitative analysis of plant cell structures
两种物种和两种核型？西番莲属植物（Passifloraceae）中西番莲（Passiflora foetida L.）与西番莲（P. vesicaria L.）之间的细胞遗传分化	Zirpoli, B.	PDF	N/A	Two species and two karyotypes? Cytogenetic differentiation between Passiflora foetida L. and P. vesicaria L. (Passifloraceae)
CRISPR敲除偏向冬季的SUT4基因改变了田间种植杂交杨树的物候、生物量积累和繁殖能力。	Tuma, T. T.	PDF	N/A	CRISPR knockout of winter-biased SUT4 alters phenology, biomass accrual, and fertility of field-grown hybrid poplar
苜蓿（Medicago truncatula）中的LYR4胞内域在免疫信号传导中充当支架，与其磷酸化活性无关。	Simonsen, B.	PDF	N/A	The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity
印度次喜马拉雅地区传统作物的生物文化脆弱性	Jaggi, H.	PDF	N/A	Biocultural vulnerability of traditional crops in the Indian Trans Himalaya
生长素-水杨酸跷跷板调节植物生长与食草动物防御之间的年龄依赖性平衡	Han, W.-H.	PDF	N/A	Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense
在马达加斯加的自然短日照和低肥力条件下，qHd7.1数量性状位点上的DJ123等位基因促进了早熟，且不影响产量。	Kondo, K.	PDF	N/A	A DJ123 allele at the heading date quantitative trait locus qHd7.1 promotes early heading without yield penalties under natural short-day and low fertility conditions in Madagascar
水力机械信号的统一框架：植物信号是否随流而动？	Bacheva, V.	PDF	N/A	A unified framework for hydromechanical signaling: Do plant signals go with the flow?
使用单色X射线荧光分析法对植物组织中的定量轻元素（钠和钾）进行分析	Kahlon, P. S.	PDF	N/A	Quantitative light element (sodium and potassium) profiling in plant tissues using monochromatic X-ray fluorescence analysis
核孔复合体在植物中充当pri-miRNA转录和加工的枢纽	Gonzalo, L.	PDF	N/A	The Nuclear Pore Complex acts as a hub for pri-miRNA transcription and processing in plants
可溶性CD52免疫抑制的分子基础由N-连接和O-连接糖基与HMGB1 Box B的相互作用所定义。	DeBono, N. J.	PDF	N/A	The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 Box B
基底隧道调节透明质酸合酶中的底物特异性转换	Zhu, K.	PDF	N/A	Substrate tunnel regulates substrate specificity switching in hyaluronan synthase
CRB2耗竭诱导YAP信号传导并破坏足细胞的机械感应	Sun, Y.	PDF	N/A	CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
Shaker钾离子通道电压门控及达伐吡啶结合的结构基础：闭合状态模型揭示	Pinto-Anwandter, B. I.	PDF	N/A	Structural Basis for Voltage Gating and Dalfampridine Binding in the Shaker Potassium Channel Revealed by Closed-State Model
同步辐射扫描化石的自动分割	During, M. A. D.	PDF	N/A	Automated segmentation of synchrotron-scanned fossils
大麦可能是根寄生杂草列当的潜在陷阱作物。	Inoue, M.	PDF	N/A	Barley is a potential trap crop for root parasitic weeds broomrapes
根系重塑机制与耐盐权衡：HKT1、TMAC2和TIP2;2在拟南芥中的作用	Alshareef, N.	PDF	N/A	Root Remodeling Mechanisms and Salt Tolerance Trade-Offs: The Roles of HKT1, TMAC2, and TIP2;2 in Arabidopsis
人抗体识别的流感H1和H3血凝素上的保守位点	Maurer, D. P.	PDF	N/A	Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies
拓扑异构酶1活性的表观遗传调控揭示了癌症的脆弱性	Lee, T.	PDF	N/A	Epigenetic control of Topoisomerase 1 activity presents a cancer vulnerability
实验生物化学家和其他分子科学家机器学习入门	Vince, M. J.	PDF	N/A	Getting Started with Machine Learning for Experimental Biochemists and Other Molecular Scientists
使用天然质谱技术通过丙氨酸扫描定义膜蛋白-脂质相互作用位点	Jayasekera, H. S.	PDF	N/A	Alanine Scanning to Define Membrane Protein-Lipid Interaction Sites Using Native Mass Spectrometry
通过激光诱导的Soret效应实现亚稳态相分离液滴生成及长时间DNA富集	Kobayashi, M.	PDF	N/A	Metastable phase-separated droplet generation and long-time DNA enrichment by laser-induced Soret effect
一个用于罕见癌症靶点发现的框架	Li, B.	PDF	N/A	A framework for target discovery in rare cancers
姜黄素和胡椒碱纳米颗粒调节前列腺癌中的类固醇生物合成	Yakubu, J.	PDF	N/A	Nanoparticles with Curcumin and Piperine Modulate Steroid Biosynthesis in Prostate Cancer
杜氏栀子（Gardenia duerrii）（Gardenieae科：茜草科），一种来自印度的新物种，以及Gardenia resinifera Roth的重新定型	K, R. K.	PDF	N/A	Gardenia duerrii (Gardenieae : Rubiaceae), a new species from India and Neotypification of Gardenia resinifera Roth
默认模式网络中经验的碎片化和多线程处理	Yazin, F.	PDF	N/A	Fragmentation and Multithreading of Experience in the Default-Mode Network
在健康泰国人群中，通过威斯康星卡片分类测试测量的认知变异性的蛋白质组关联：一种机器学习方法	Chen, C.	PDF	N/A	Proteomic associations with cognitive variability as measured by the Wisconsin Card Sorting Test in a healthy Thai population: A machine learning approach
将宿主状况预测因子整合到病毒排放的时空多尺度模型中	Kramer, A. M.	PDF	N/A	Integrating predictors of host condition into spatiotemporal multi-scale models of virus shedding
致癌性改变、种族与接受体细胞肿瘤下一代测序的美国转移性前列腺癌退伍军人生存率的关系	Valle, L. F.	PDF	N/A	Oncogenic Alterations, Race, and Survival in US Veterans with Metastatic Prostate Cancer Undergoing Somatic Tumor Next Generation Sequencing
生物医学数据的AI准备度：Bridge2AI建议	Clark, T.	PDF	N/A	AI-readiness for Biomedical Data: Bridge2AI Recommendations
降低ETFDH表达可优化癌细胞的生物能量学	Papadopoli, D.	PDF	N/A	Reduction in ETFDH expression optimizes cancer cell bioenergetics
一种自适应自回归扩散方法用于设计主动人源化抗体和纳米抗体	Ma, J.	PDF	N/A	An adaptive autoregressive diffusion approach to design active humanized antibody and nanobody
高效推理、训练与微调蛋白质语言模型	Celik, M. H.	PDF	N/A	Efficient Inference, Training, and Fine-tuning of Protein Language Models
在癌症单细胞研究中，通过筛选去除高线粒体含量的细胞，可以有效清除那些代谢发生改变的恶性细胞群体，这些细胞群体在生物学上仍然具有活力。	Yates, J.	PDF	N/A	Filtering cells with high mitochondrial content removes viable metabolically altered malignant cell populations in cancer single-cell studies
scMoE：用于从异质性单细胞RNA测序数据中学习层次化、细胞类型特异性和可解释表示的单细胞专家混合模型	Huang, M.	PDF	N/A	scMoE: single-cell mixture of experts for learning hierarchical, cell-type-specific, and interpretable representations from heterogeneous scRNA-seq data
致癌长链非编码RNA NEAT1和MALAT1在二维单层与三维肿瘤球体培养中的差异表达及其对癌症进展的意义	Ghosh, A.	PDF	N/A	Differential expression of oncogenic lncRNAs NEAT1 and MALAT1 in 2D monolayer vs. 3D tumoroid culture and its implications in cancer progression
Unc-51样激酶1（ULK1）调控细菌泛素化和p62招募在李斯特菌异噬清除过程中的作用	Siqueira, M. S.	PDF	N/A	Unc-51-like Kinase 1 (ULK1) Regulates Bacterial Ubiquitylation and p62 Recruitment during Xenophagic Clearance of Listeria monocytogenes
甘蓝型油菜高温萌发适应性的未开发多样性	Tiret, M.	PDF	N/A	An unexplored diversity for adaptation of germination to high temperatures in Brassica species
来自热河生物群的具冠白垩纪反鸟类中的虹彩结构色	LI, Z.	PDF	N/A	Iridescent structural coloration in a crested Cretaceous enantiornithine bird from Jehol Biota
组装钌复合物形成钌体，释放铁蛋白吞噬介导的肿瘤抑制作用	Meng, C.	PDF	N/A	Assembling Ruthenium Complexes to Form Ruthenosome Unleashing Ferritinophagy-mediated Tumor Suppression
半胱氨酸氧化对SARS-CoV-2刺突蛋白构象变化的影响：来自原子模拟的见解	Ghasemitarei, M.	PDF	N/A	Effect of cysteine oxidation in SARS-CoV-2 Spike protein on its conformational changes: insights from atomistic simulations
血管生成和免疫预测因素在伴有静脉瘤栓的肾细胞癌中对新辅助阿昔替尼反应的影响	Wray, R.	PDF	N/A	Angiogenic and Immune Predictors of Neoadjuvant Axitinib Response in Renal Cell Carcinoma with Venous Tumour Thrombus
染色体不稳定性通过细胞外囊泡中的EFEMP1促进细胞迁移和侵袭	Foijer, F.	PDF	N/A	Chromosomal instability promotes cell migration and invasion via EFEMP1 in extracellular vesicles
脂联素受体激动剂可预防杜氏肌营养不良小鼠模型中的右心室组织病理学变化。	Gandhi, S.	PDF	N/A	Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy
TIR信号激活了细菌中的类似胱天蛋白酶的免疫反应。	ROUSSET, F.	PDF	N/A	TIR signaling activates caspase-like immunity in bacteria
一项新的筛选检测揭示，氨基糖苷类抗生素干扰Tau/MDM2相互作用。	Sola, M.	PDF	N/A	A new screening assay reveals that aminoglycoside antibiotics interfere with the Tau/MDM2 interaction
将IICR扩展到复杂的非平稳结构化模型	Jouniaux, A.	PDF	N/A	Extending the IICR to complex non-stationary structured models
从geissoschizine出发的单萜吲哚生物碱的分歧生物合成	Kamileen, M. O.	PDF	N/A	Divergent biosynthesis of monoterpene indole alkaloids from geissoschizine
替代性转录本通过重新编码人类基因，表达出重叠且发生移码的微型蛋白质。	Su, H.	PDF	N/A	Alternative transcripts recode human genes to express overlapping, frameshifted microproteins
黄芩素通过下调新生儿Fc受体并通过NF-κB信号通路改善实验性溃疡性结肠炎的复发	Hu, H.	PDF	N/A	Baicalein ameliorates experimental ulcerative colitis recurrency by downregulating neonatal Fc receptor via the NF-κB signaling pathway
从等位基因包含中学习抗体序列约束	Jagota, M.	PDF	N/A	Learning antibody sequence constraints from allelic inclusion
纽芬兰与拉布拉多鳕鱼崩溃后的快速生态系统变化	Wudrick, A.	PDF	N/A	Rapid ecosystem change after the cod collapse in Newfoundland & Labrador
何时信任表观遗传时钟：避免衰老干预中的假阳性。	Borrus, D. S.	PDF	N/A	When to Trust Epigenetic Clocks: Avoiding False Positives in Aging Interventions.
对Batrachochytrium dendrobatidis GPL JEL423的近乎完整的端粒到端粒基因组组装揭示了CBM18基因家族的扩展和M36金属蛋白酶基因家族的收缩。	Helmstetter, N.	PDF	N/A	A near-complete telomere-to-telomere genome assembly for Batrachochytrium dendrobatidis GPL JEL423 reveals a CBM18 gene family expansion and a M36 metalloprotease gene family contraction.
可转座元件小RNA和长RNA在老化大脑中的作用及其对亨廷顿病和帕金森病的启示	Dayama, G.	PDF	N/A	Transposable element small and long RNAs in aging brains and implications in Huntington's and Parkinson's disease
全基因组变异分析揭示了埃及伊蚊及其形态变种埃及伊蚊var. luciensis之间不同的遗传特征。	Gupta, B.	PDF	N/A	Genome-wide variant analysis reveals divergent genetic signatures in Aedes aegypti and its morphological variant Aedes aegypti var. luciensis
WRI1在天然橡胶中多乳汁代谢途径整合调控中的普遍功能	Fan, R.	PDF	N/A	Universal function of WRI1 involved in integrated regulation of multiple latex metabolism pathways in Natural Rubber
在黑色素瘤起始过程中，吸引子状态区域先于神经嵴命运出现。	McConnell, A. M.	PDF	N/A	An attractor state zone precedes neural crest fate in melanoma initiation
线粒体靶向质体醌疗法改善了小鼠卵巢癌恶病质前期的早期肌肉无力症状	Delfinis, L. J.	PDF	N/A	Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice
CXADR是一种人IgG Fc受体。	Emig, C. J.	PDF	N/A	CXADR is a Human IgG Fc Receptor
不同的母胎免疫特征描绘了尿路感染后早产的发作	Ottinger, S.	PDF	N/A	Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection
在人类慢性基孔肯雅病毒性关节炎疾病中鉴定免疫原性和交叉反应的基孔肯雅病毒特异性CD4+ T细胞表位	Agarwal, R.	PDF	N/A	Identification of immunogenic and cross-reactive chikungunya virus-specific CD4+ T cell epitopes in chronic chikungunya viral arthritic disease in humans
小鼠接种高效和低效全细胞百日咳疫苗后产生的抗体谱	Adewunmi, Y.	PDF	N/A	Antibody Profiles Elicited by Potent and Subpotent Whole Cell Pertussis Vaccines in Mice
2,3,7,8-四氯二苯并-对-二噁英（TCDD）引发了与肝脏芳香烃受体（AHR）介导的差异基因表达相关的剂量依赖性小鼠尿液代谢组变化。	Sink, W. J.	PDF	N/A	2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) elicited dose-dependent shifts in the murine urinary metabolome associated with hepatic AHR-mediated differential gene expression
无花果蜂的基因组揭示了无花果-无花果蜂共生关系中的适应与共进化	Lo, B.-W.	PDF	N/A	Genomes of Wiebesia fig wasps reveal the adaptation and codiversification in fig-fig wasp mutualism
通过空间脂质组学和蛋白质组学相关性进行异质性评估和蛋白质通路预测：推进用于人类胶质母细胞瘤预后的干蛋白质组学概念	Lagache, L.	PDF	N/A	Heterogeneity Assessment and Protein Pathway Prediction via Spatial Lipidomic and Proteomic Correlation: Advancing Dry Proteomics concept for Human Glioblastoma Prognosis
AMPK激活通过其去磷酸化促进TFEB的转录激活。	Negoita, F.	PDF	N/A	AMPK activation promotes transcriptional activation of TFEB through its dephosphorylation
利用β-孔形成毒素Aerolysin增强单链纳米体对Notch的抑制及亲和力	Lemmex, A.	PDF	N/A	Single-chain nanobody inhibition of Notch and avidity enhancement utilizing the β-pore forming toxin Aerolysin
利用时序卷积生成语言模型设计功能性酵母启动子序列	Alsaggaf, I.	PDF	N/A	Functional yeast promoter sequence design using temporal convolutional generative language models
部分特征化的拓扑结构指导可靠的无锚点单细胞RNA整合	He, C.	PDF	N/A	Partially characterized topology guides reliable anchor-free scRNA integration
膜联蛋白A6通过与三阴性乳腺癌细胞中的SNAP23相互作用，调节促炎细胞因子和外泌体的分泌。	Sakwe, N. I.	PDF	N/A	Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells
钴原卟啉IX对小鼠粒细胞动员和代谢标志物的剂量和时间依赖性效应	Bednarz, A.	PDF	N/A	Dose- and time-dependent effects of cobalt protoporphyrin IX on granulocyte mobilization and metabolic markers in mice
转录组分析揭示了幼年公牛鳟鱼亚致死热应激阈值的见解	Best, C.	PDF	N/A	Transcriptional profiling provides insights on sublethal thermal stress thresholds in juvenile bull trout
线粒体靶向抗氧化剂SkQ1可预防与线粒体相关的细胞凋亡，但不能预防坏死性凋亡或卵巢癌中的骨骼肌萎缩。	Khajehzadehshoushtar, S.	PDF	N/A	The mitochondrial-targeted antioxidant SkQ1 prevents mitochondrial-linked apoptosis but not necroptosis or skeletal muscle atrophy in ovarian cancer
利用iColonEpithelium代谢重建理解人类结肠上皮细胞中与疾病相关的代谢变化	Jiang, B.	PDF	N/A	Understanding disease-associated metabolic changes in human colon epithelial cells using iColonEpithelium metabolic reconstruction
成虫饮食对昆虫Narnia femorata（半翅目：Coreidae科）的角质层厚度和抗损伤能力有显著影响。	Greenway, E. V.	PDF	N/A	Adult diet strongly affects cuticle thickness and its injury resistance in the insect Narnia femorata (Hemiptera: Coreidae)
用于研究基因组组织与转录调控相互作用的计算机纳米显微镜	Gopi, S.	PDF	N/A	In silico nanoscope to study the interplay of genome organization and transcription regulation
人类世鱼类食物网的退化	Carvajal-Quintero, J. D.	PDF	N/A	Degradation of fish food webs in the anthropocene
合作最大化生物多样性	Godoy, O.	PDF	N/A	Cooperation maximizes biodiversity
开发和验证用于eDNA监测和认证10种商业上重要的秘鲁海洋物种的多功能种特异性引物检测方法	Marin, A.	PDF	N/A	Development and validation of versatile species-specific primer assays for eDNA monitoring and authentication of 10 commercially important Peruvian marine species
通过遗传免疫表型分析，探索冈比亚按蚊免疫细胞生物学的新维度	Samantsidis, G.-R.	PDF	N/A	Exploring new dimensions of immune cell biology in Anopheles gambiae through genetic immunophenotyping
子宫内膜在着床窗口期细胞成分的变化与复发性流产相关。	Reddin, I. G.	PDF	N/A	Changes in the cellular composition of the endometrium during the implantation window are associated with recurrent pregnancy loss
蕨类植物满江红（Azolla caroliniana）的基因组组装	Song, M. J.	PDF	N/A	The genome assembly of the duckweed fern, Azolla caroliniana
gp82结合的原子级洞察：对克鲁斯锥虫宿主细胞入侵的微秒级、百万原子探索	Rosa, R. S. L.	PDF	N/A	Atomistic Insights into gp82 Binding: A Microsecond, Million-Atom Exploration of Trypanosoma cruzi Host-Cell Invasion
铜绿假单胞菌H16中利用H2生产木糖醇	Jämsä, T.	PDF	N/A	H2-driven xylitol production in Cupriavidus necator H16
解析蛋白质-碳水化合物界面的多样性：来自多尺度研究的见解	Gheeraert, A.	PDF	N/A	Unraveling the diversity of protein-carbohydrate interfaces: insights from a multi-scale study
通过自动化计算流程HitList发现重要人畜和植物真菌病原体的新靶点	Condon, D. E.	PDF	N/A	Discovery of Novel Targets for Important Human and Plant Fungal Pathogens via Automated Computational Pipeline HitList
通过碱基对基序能量进行RNA二级结构的深度可泛化预测	Zhu, H.	PDF	N/A	Deep generalizable prediction of RNA secondary structure via base pair motif energy
长读长比对堆积的K-mer分析用于结构变异基因分型	ENGLISH, A. C.	PDF	N/A	K-mer analysis of long-read alignment pileups for structural variant genotyping
Metagenomics-Toolkit：灵活高效的云端宏基因组学工作流程，具备机器学习驱动的资源分配功能	Belmann, P.	PDF	N/A	Metagenomics-Toolkit: The Flexible and Efficient Cloud-Based Metagenomics Workflow featuring Machine Learning-Enabled Resource Allocation
单个癌细胞中多种ecDNA类型的维持	Scanu, E.	PDF	N/A	The maintenance of multiple ecDNA types in single cancer cells
利用ReSisTrace谱系追踪技术揭示急性髓系白血病中FLT3抑制剂的预敏化剂	Eriksson, J.	PDF	N/A	Uncovering pre-sensitizing agents to FLT3 inhibitors in acute myeloid leukemia with ReSisTrace lineage tracing
单链DNA结合因子SUB1/PC4减轻端粒处的复制应激，是ALT癌细胞的脆弱点	Dubois, J.-C.	PDF	N/A	The Single-Stranded DNA-Binding Factor SUB1/PC4 Alleviates Replication Stress at Telomeres and is a Vulnerability of ALT Cancer Cells
IRE1依赖的GOLIM4表达控制蛋白质分泌以调节胶质母细胞瘤细胞的粘附和迁移	Bakambamba, K.	PDF	N/A	IRE1-dependent GOLIM4 expression controls protein secretion to modulate glioblastoma cell adhesion and migration
综合结构-功能分析揭示了影响致癌KRAS活性的获得性和丧失性功能机制	Kwon, J.	PDF	N/A	Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity
染色体外DNA驱动胶质母细胞瘤中的癌基因空间异质性与演化	Noorani, I.	PDF	N/A	Extrachromosomal DNA driven oncogene spatial heterogeneity and evolution in glioblastoma
抑制调节性T细胞中的UBE2N可增强抗癌免疫力	Miao, W.	PDF	N/A	Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer
贫血和组织缺氧是疟疾低乳酸血症的主要决定因素。	Georgiadou, A.	PDF	N/A	Anemia and tissue hypoxia are major determinants of malarial hypelactatemia
长链酰基辅酶A脱氢酶的丧失可预防急性肾损伤	Chiba, T.	PDF	N/A	Loss of long-chain acyl-CoA dehydrogenase protects against acute kidney injury
由羟基醌形成驱动的CBD毒性	Montero, M. I.	PDF	N/A	Cannabidiol Toxicity Driven by Hydroxyquinone Formation
新型链霉菌SCA4-21对香蕉枯萎病的生物防治效果及机制	Qi, D.	PDF	N/A	Biocontrol efficiency and mechanism of novel Streptomyces luomodiensis SCA4-21 against banana Fusarium wilt
SLB-msSIM：一种基于光谱库的多重分段SIM平台，用于单细胞蛋白质组学分析	Senavirathna, L.	PDF	N/A	SLB-msSIM: a spectral library-based multiplex segmented SIM platform for single-cell proteomic analysis
机械感受器在响应微生物感染时启动先天免疫	Stucchi, G.	PDF	N/A	Mechanoreceptors initiate innate immunity in response to microbial infections
生成人类诱导多能干细胞（iPSC）衍生的胰腺类器官，以研究胰腺发育和疾病	Darrigrand, J.-F.	PDF	N/A	Generation of human iPSC-derived pancreatic organoids to study pancreas development and disease
无特质匹配：使用对应分析分析交互网络的潜在结构	Nicvert, L.	PDF	N/A	Trait matching without traits: using correspondence analysis to analyze the latent structure of interaction networks
土地利用强度、生产力和地上丰富度对温带草地种子雨的影响	Klinger, Y. P.	PDF	N/A	Impact of land-use intensity, productivity, and aboveground richness on seed rain in temperate grasslands
长链非编码RNA NEAT1和MALAT1的系统发育研究：推断结构-功能联系	Arkhipova, K.	PDF	N/A	Phylogenetic Study of Long Non-Coding RNA NEAT1 and MALAT1 to Infer Structural-Functional Connection
入侵植物马缨丹（Lantana camara）的种群结构受其交配系统的影响。	Praveen, P.	PDF	N/A	The population structure of invasive Lantana camara is shaped by its mating system
PWWP-ADD和DNMT3B1的N端结构域赋予了对发育调控的CpG岛甲基化的特异性	Yasmin, K.	PDF	N/A	PWWP-ADD and N-terminal domains of DNMT3B1 confer specificity for developmentally regulated CpG island methylation
有机光电纳米生物界面实现了多尺度生物调控	Mueller, C.	PDF	N/A	Organic opto-nanobiointerface enables multiscale biomodulation
等分散泊松分布（Equi-Under-Dispersed Possion Distribution，简称EUPoisson）	Hassan, M.	PDF	N/A	Equi-Under-Dispersed Possion Distribution (EUPoisson)
智能数据工厂：面向主动学习驱动分子数据采集的志愿者计算平台	Ghukasyan, T.	PDF	N/A	SMART DATA FACTORY: VOLUNTEER COMPUTING PLATFORM FOR ACTIVE LEARNING-DRIVEN MOLECULAR DATA ACQUISITION
一种高吞吐量的单分子平台，用于研究DNA超螺旋效应对蛋白质-DNA相互作用的影响	Lee, H.	PDF	N/A	A high throughput single molecule platform to study DNA supercoiling effect on protein-DNA interactions
单核分析未折叠蛋白反应（SNUPR）：揭示多发性骨髓瘤中硼替佐米耐药机制的新方法	Arguello, R. J.	PDF	N/A	Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma
使用区间分析设计满足稳态规格的生物分子电路参数区间	Prakash, R.	PDF	N/A	Design of Parameter Intervals to Meet Steady-State Specifications in Biomolecular Circuits using Interval Analysis
洗牌：扩展合成生物学工具包以用于类似洗牌子的重组系统	Katalinic, J.	PDF	N/A	Do the shuffle: Expanding the synthetic biology toolkit for shufflon-like recombination systems
多细胞比例-积分-微分控制对生物过程的鲁棒调节	Martinelli, V.	PDF	N/A	Multicellular Proportional-Integral-Derivative Control for Robust Regulation of Biological Processes
太暗、太亮和刚刚好：适应光应激和限制下的莱茵衣藻昼夜节律程序的系统分析	Dupuis, S.	PDF	N/A	Too dim, too bright, and just right: Systems analysis of the Chlamydomonas diurnal program upon acclimation to light stress and limitation
鞭毛运动和黏液环境影响铜绿假单胞菌在慢性肺部感染中的聚集介导的抗生素耐药性	Higgs, M. G.	PDF	N/A	Flagellar motility and the mucus environment influence aggregation mediated antibiotic tolerance of Pseudomonas aeruginosa in chronic lung infection
利用分子生物学和微生物学相结合的方法，鉴定英国蚕豆根腐病相关的镰刀菌种类	Attar, B.	PDF	N/A	Identifying the Fusarium species involved in foot rot disease of faba beans in the UK using a combined molecular and microbiological approach
基于营养的根际微生物群工程原理，通过活体微生物接种剂调控作物产量	Huang, Y.	PDF	N/A	Principles of nutrition-dependent root-microbiome engineering for regulating crop yield via live microbial inoculants
抑制白假丝酵母毒力因子由维罗纳气单胞菌V03衍生的环二肽实现	Sekar, J.	PDF	N/A	Inhibition of Candida albicans virulence factor by cyclic dipeptides derived from Aeromonas veronii V03
增强抗菌药物耐药性监测：基于牛津纳米孔测序技术（ONT）的核心质粒多位点序列分型（cpMLST）	Xavier, B. B.	PDF	N/A	Enhancing antimicrobial resistance monitoring: Core Plasmid Multi-Locus sequence typing (cpMLST) with Oxford Nanopore sequencing technology (ONT)
理解结核分枝杆菌的流行病学和发病机制，结合非冗余泛基因组和群体遗传学	Zhou, Y.	PDF	N/A	Understanding the epidemiology and pathogenesis of Mycobacterium tuberculosis with non-redundant pangenome and population genetics
碳青霉烯耐药肺炎克雷伯菌的临床特征、耐药基因及毒力分析	He, J.	PDF	N/A	Clinical characteristics, drug-resistance genes and virulence analysis of carbapenem-resistant Klebsiella pneumoniae
基于RNA toehold开关的报告分析法用于评估细菌对反义寡核苷酸的摄取	Sarkar, P.	PDF	N/A	RNA toehold switch-based reporter assay to assess bacterial uptake of antisense oligomers
关键刺突蛋白突变的流行及其对孟加拉国锡尔赫特市COVID-19临床表现影响有限	Akter, S.	PDF	N/A	Prevalence of Key Spike Protein Mutations and Their Limited Effect on COVID-19 Clinical Manifestations in Sylhet, Bangladesh
长期免疫效果：经伽马射线照射的SARS-CoV-2 S1蛋白亚单位疫苗微针阵列贴片在小鼠中的研究	Kim, E.	PDF	N/A	Long-term Immunity of a Microneedle Array Patch of SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice
FBXW7通过减轻c-MYC对丙酮酸羧化酶的抑制作用，支持代谢灵活性。	Lisci, M.	PDF	N/A	FBXW7 alleviates c-MYC repression of pyruvate carboxylase to support metabolic flexibility
探究DNA损伤位点揭示了依赖于上下文和新的DNA损伤反应因子	Cardoso da Silva, R.	PDF	N/A	Probing DNA damage sites reveals context-dependent and novel DNA damage response factors
依赖于序列的跨膜转运蛋白介导的膜界面螺旋插入的尺度	Grau, B.	PDF	N/A	Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes
抑制衰老的载脂蛋白E4小鼠体内的胆固醇储存酶ACAT1/SOAT1，改变了它们大脑的炎症特征。	Huynh, T. N.	PDF	N/A	Inhibiting the cholesterol storage enzyme ACAT1/SOAT1 in aging Apolipoprotein E4 mice alter their brains inflammatory profiles
水热处理酵母细胞壁在单独条件下抑制MCF7细胞的生长。	KITAGAWA, T.	PDF	N/A	Hydrothermally treated yeast cell wall suppresses the growth of MCF7 cells under isolated conditions.
进化尺度酶学使我们能够在多峰催化景观中预测生化常数	Muir, D. F.	PDF	N/A	Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape
利用数据不平衡性来增强化合物-蛋白质相互作用预测模型	Lin, W.	PDF	N/A	Utilizing data imbalance to enhance compound-protein interaction prediction models
离子迁移谱引导的分子鉴别：脂质组学实验中区分缩醛磷脂与其他醚脂的方法	Koch, J.	PDF	N/A	Trapped ion mobility spectrometry-guided molecular discrimination between plasmalogens and other ether lipids in lipidomics experiments
唾液代谢组分的构成与SARS-CoV2感染及COVID-19疾病的严重程度显著相关。	Larios-Serrato, V.	PDF	N/A	Composition of saliva metabolome is significantly associated with SARS-CoV2 infection and with severity of COVID-19 disease
使用合成RNA评估直接RNA测序中的多腺苷酸尾长度推断。	Chang, J. J.-Y.	PDF	N/A	Using synthetic RNA to benchmark poly(A) length inference from direct RNA sequencing.
孟加拉国禽类样本中分离出的细菌中的重金属与抗生素共耐药性：一种新兴的环境威胁	Sarker, A.	PDF	N/A	Heavy Metal and Antibiotic Co-resistance in Bacteria Isolated from Poultry Samples in Bangladesh: An Emerging Environmental Threat
肺和肠道微生物群对SARS-CoV-2感染的不同反应：武汉株与Omicron株在K18-hACE2转基因小鼠中的比较研究	Kim, C. W.	PDF	N/A	Differential Responses of Lung and Intestinal Microbiota to SARS-CoV-2 Infection: A Comparative Study of the Wuhan and Omicron Strains in K18-hACE2 tg Mice
大麦miRNAs及其靶标在发育早期对热胁迫的响应调控	Kruszka, K.	PDF	N/A	Barley miRNAs and their targets regulation in response to heat stress at the early stage of development
综合系统生物学研究表明，线粒体功能和代谢的紊乱是导致保留射血分数的心力衰竭（HFpEF）的关键因素。	Gibb, A. A.	PDF	N/A	Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF)
HT SpaceM：一种高通量且可重复的小分子单细胞代谢组学方法	Delafiori, J.	PDF	N/A	HT SpaceM: A High-Throughput and Reproducible Method for Small-Molecule Single-Cell Metabolomics
β-淀粉样蛋白损害蛋白酶体结构和功能。蛋白酶体激活可减轻淀粉样蛋白引起的毒性和认知缺陷。	Davidson, K.	PDF	N/A	β-Amyloid impairs Proteasome structure and function. Proteasome activation mitigates amyloid induced toxicity and cognitive deficits
使用多重竞争性等位基因特异性PCR（mxKASP）基因分型确定合子性	de Visser, M. C.	PDF	N/A	Determining zygosity with multiplex Kompetitive Allele-Specific PCR (mxKASP) genotyping
在碱基切除修复途径的下游步骤中，LIG1和LIG3α在8-oxoG旁路过程中对polβ错配插入产物进行诱变连接	Lee, K. M.	PDF	N/A	Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway
对倍半萜香豆素合酶反应机制的预测表明其与三萜生物合成存在直接的进化联系。	Stephenson, M. J.	PDF	N/A	Prediction of the reaction mechanisms of sesquiterpene coumarin synthases supports a direct evolutionary link with triterpene biosynthesis.
ProteinWeaver：一个用于可视化本体注释蛋白质网络的网络工具	Anderson, O.	PDF	N/A	ProteinWeaver: A Webtool to Visualize Ontology-Annotated Protein Networks
在感染沃尔巴克氏菌株wAlbB的埃及伊蚊孟加拉国品系中，适应性与登革病毒抑制的关系	Al-Amin, H. M.	PDF	N/A	Fitness compatibility and dengue virus inhibition in a Bangladeshi strain of Aedes aegypti infected with the Wolbachia strain wAlbB
以微外显子下游剪接供体位点为靶点的寡核苷酸：自闭症创新疗法	Martinez-Pizarro, A.	PDF	N/A	OLIGONUCLEOTIDES TARGETING THE SPLICE ACCEPTOR SITE DOWNSTREAM OF A MICROEXON AS AN INNOVATIVE THERAPY FOR AUTISM
实验田试验模型展示了气候危机将如何改变Vitis sp. L'Acadie Blanc叶片微环境和果实微环境的真菌群落。	Blakney, A. J. C.	PDF	N/A	Experimental field trials model how the climate crisis will alter the phyllosphere and carposphere fungal communities of Vitis sp. L'Acadie Blanc
贾第虫晚期ESCRT组分的不同功能：基于亚细胞分布和蛋白质相互作用的见解	Patra, N.	PDF	N/A	Divergent Functions of Late ESCRT Components in Giardia lamblia: Insights from Subcellular Distributions and Protein Interactions
象牙喙啄木鸟与蓝松鸦在频谱图层面的对比显示出差异	Williams, J. D.	PDF	N/A	Ivory-billed Woodpecker and Blue Jay kent comparisons at spectrogram level reveal differences
保守的基因内容和独特的系统发育历史特征了“bloopergene”，这是Triturus平衡致死系统的基础。	de Visser, M. C.	PDF	N/A	Conserved gene content and unique phylogenetic history characterize the 'bloopergene' underlying Triturus' balanced lethal system
丝状真菌核基因组中的Zymocin样杀伤毒素基因簇	Heneghan, P. G.	PDF	N/A	Zymocin-like killer toxin gene clusters in the nuclear genomes of filamentous fungi
没有其微生物组的果蝇的实验进化	Malwade, A.	PDF	N/A	Experimental evolution of Drosophila without its microbiome
父系基因组消除、单基因复制和非典型性染色体系统的进化遗传学	Hitchcock, T. J.	PDF	N/A	Paternal genome elimination, monogenic reproduction, and the evolutionary genetics of atypical sex chromosome systems
信号调节结构如何演变：来自进化模型的见解	Asgari, D.	PDF	N/A	How the Structure of Signaling Regulation Evolves: Insights from an Evolutionary Model
MIRAGE：一种结合变异功能信息的贝叶斯稀有变异关联分析方法	Han, S.	PDF	N/A	MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants
Mettl5协调蛋白质的生成和PERIOD的降解，以调节果蝇的睡眠	Wu, X.	PDF	N/A	Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila
NewtCap：一种高效的目标捕获方法，用于提升蝾螈科（真蝾螈和蝾螈）基因组研究	de Visser, M. C.	PDF	N/A	NewtCap: an efficient target capture approach to boost genomic studies in Salamandridae (True Salamanders and Newts)
一种用于纳米孔直接RNA测序中嵌合体伪影检测的基因组语言模型	Li, Y.	PDF	N/A	A Genomic Language Model for Chimera Artifact Detection in Nanopore Direct RNA Sequencing
从原始视频到行为分析：一种用于野外活动监测和行为识别的自动化流程	Silva, L. R.	PDF	N/A	From raw footage to behaviour: an automated pipeline for activity monitoring and behaviour identification in the wild
邻近标记揭示了人类线粒体导入受体蛋白TOMM20和TOMM70的不同相互作用伙伴	Akram, S.	PDF	N/A	Proximity labeling reveals differential interaction partners of the human mitochondrial import receptor proteins TOMM20 and TOMM70
微尺度液滴中多能干细胞的培养可调节分化和组织模式化，使其趋向于芯片上的类器官	Vertti-Quintero, N.	PDF	N/A	Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip
用于选择性捕获和释放肝细胞来源的细胞外囊泡作为肝病生物标志物的磁点击捕获释放技术	Booijink, R.	PDF	N/A	The Mag-Click-Capture-Release Technology for Selective Capture and Release of Hepatocyte-Derived Extracellular Vesicles as Biomarkers for Liver Disease
单细胞转录组学揭示了硬皮病相关性肺动脉高压与特发性肺动脉高压在病理生物学上的差异，并为精准靶向治疗提供了机会。	Tuhy, T.	PDF	N/A	Single-cell transcriptomics reveal diverging pathobiology and opportunities for precision targeting in scleroderma-associated versus idiopathic pulmonary arterial hypertension
LncRAnalyzer：揭示高粱基因组中的长非编码RNA并探索基因共表达模式	Nikhil, S.	PDF	N/A	LncRAnalyzer: Uncovering Long Non-Coding RNAs and Exploring Gene Co-expression Patterns in Sorghum Genomics
μPIX：利用生成式人工智能实现增强、个性化和可持续的显微镜技术	Bon, G.	PDF	N/A	μPIX: Leveraging Generative AI for Enhanced, Personalized and Sustainable Microscopy
关于机器学习应用的蛋白质序列中注释的同源区域预处理	Malhis, N.	PDF	N/A	Pre-processing annotated homologous regions in protein sequences concerning machine-learning applications
改进的蛋白质相互作用模型预测了人类细胞系之间复合物的差异	Wilkins, G. R.	PDF	N/A	Improved protein interaction models predict differences in complexes between human cell lines
土壤有机质矿化的计算微生物学：利用曲线骨架概念划分计算机断层扫描图像中的三维孔隙空间	Belghali, Z.	PDF	N/A	Computational microbiology of soil organic matter mineralization: Use of the concept of curve skeleton to partition the 3D pore space in computed tomography images
RSV基因组中的G四链体：潜在的抗病毒靶点。	Bose, D.	PDF	N/A	G-quadruplexes in the RSV genome: potential anti-viral targets.
通过细胞周期实现核组织的三维记忆	Fujishiro, S.	PDF	N/A	Three-dimensional memory of nuclear organization through cell cycles
AcMNPV核衣壳结构揭示了DNA通道组织及环状双链DNA杆状病毒的包装机制。	Effantin, G.	PDF	N/A	Structure of AcMNPV nucleocapsid reveals DNA portal organization and packaging apparatus of circular dsDNA baculovirus.
乳腺癌转移部位与单一营养水平无关	Abbott, K. L.	PDF	N/A	Site of breast cancer metastasis is independent of single nutrient levels
通过纳米动力学变化在脂质膜中实现铁死亡的体内成像	Sonay, A. Y.	PDF	N/A	In vivo imaging of ferroptosis through nanodynamic changes in lipid membranes
TFE3融合蛋白在转位性肾细胞癌中驱动氧化代谢、铁死亡抵抗和普遍的RNA合成。	Davidson, I.	PDF	N/A	TFE3 fusion proteins drive oxidative metabolism, ferroptosis resistance and general RNA synthesis in translocation renal cell carcinoma
植物物种在花蜜过氧化氢含量上存在差异，这是一种某些细菌和酵母能够耐受的抗菌防御机制。	Landucci, L.	PDF	N/A	Plant species vary in nectar peroxide, an antimicrobial defense tolerated by some bacteria and yeasts
高通量生物多样性调查为最亮的昆虫类群带来了新的见解	Iwaszkiewicz-Eggebrecht, E.	PDF	N/A	High-throughput biodiversity surveying sheds new light on the brightest of insect taxa
小胶质细胞状态决定多发性硬化症中的病变动态	van den Bosch, A. M.	PDF	N/A	Microglial states determine lesion dynamics in multiple sclerosis
内源性逆转录病毒样蛋白招募UBQLN2至应激颗粒，并改变其功能特性	Mohan, H. M.	PDF	N/A	Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties
模拟微重力加速α-突触核蛋白聚集并诱导体外帕金森病模型中的氧化应激	Lentini, V.	PDF	N/A	Simulated microgravity accelerates alpha-synuclein aggregation and induces oxidative stress in an in vitro Parkinson disease model
虚拟脑双胞胎的原理与操作	Hashemi, M.	PDF	N/A	Principles and Operation of Virtual Brain Twins
在烟曲霉感染期间，IFN-STAT1-CYBB轴定义了保护性浆细胞样DC与中性粒细胞之间的交叉对话。	Guo, Y.	PDF	N/A	An IFN-STAT1-CYBB Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk During Aspergillus fumigatus Infection.
心脏骤停小鼠模型中心肌炎症和转录组变化的时序动态	Panigrahi, S.	PDF	N/A	Temporal dynamics of inflammatory and transcriptome changes in the myocardium in a murine model of cardiac arrest
在多发性硬化症中连接髓鞘与爱泼斯坦-巴尔病毒特异性免疫反应：综合公共T细胞受体库的见解	Valkiers, S.	PDF	N/A	Linking myelin and Epstein-Barr virus specific immune responses in multiple sclerosis: insights from integrated public T cell receptor repertoires
建立绿色藻类Chlamydomonas incerta作为重组蛋白生产的平台	Kang, K.	PDF	N/A	Establishing the green algae Chlamydomonas incerta as a platform for recombinant protein production
一种Ⅰ型3' UTR衍生的sRNA参与了金黄色葡萄球菌中的血红素代谢和毒力	Silard, C.	PDF	N/A	A type I 3' UTR-derived sRNA is involved in heme metabolism and virulence in Staphylococcus aureus
Syntaxin11缺乏抑制CRAC通道的启动，从而抑制FHLH4患者T淋巴细胞的细胞毒性和基因表达。	Vig, M.	PDF	N/A	Syntaxin11 Deficiency Inhibits CRAC Channel Priming To Suppress Cytotoxicity And Gene Expression In FHLH4 Patient T Lymphocytes.
改进的小鼠骨髓损伤模型中通过膜内骨化研究产后骨生成的方法	Stetsiv, M.	PDF	N/A	Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model
棕榈酰化的输入蛋白α通过与NuMA的相互作用调节有丝分裂纺锤体的定向	Sutton, P. J.	PDF	N/A	Palmitoylated Importin α Regulates Mitotic Spindle Orientation Through Interaction with NuMA
通过冷冻扫描透射电子断层成像技术捕捉到的线粒体分裂瞬间的影像	Kirchweger, P.	PDF	N/A	Snapshots of Mitochondrial Fission Imaged by Cryo-Scanning Transmission Electron Tomography
G-四链体配体RHPS4通过阻断电离辐射诱导的线粒体质量和活性的增加，破坏了细胞的放射抗性。	Tricot, S.	PDF	N/A	G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation.
鞘脂类失衡加剧纤维状Tau诱导的内质膜硬化和破裂	Tittelmeier, J.	PDF	N/A	Sphingolipid imbalance aggravates fibrillar Tau-induced endomembrane rigidification and rupture
E3泛素连接酶Trip12在造血干细胞发育过程中减弱Wnt9a/Fzd9b信号传导	Ensing, J.	PDF	N/A	The E3 Ubiquitin Ligase Trip12 attenuates Wnt9a/Fzd9b signaling during hematopoietic stem cell development
PUF RNA结合蛋白FBF-2在不结合RNA的情况下维持干细胞状态。	Carrick, B. H.	PDF	N/A	The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA
小鼠胚胎在失去与子痫前期相关的丝氨酸蛋白酶前列腺素后红细胞成熟受损	Di Carlo, S.	PDF	N/A	Impaired erythroid maturation in murine embryos upon loss of the preeclampsia-associated serine protease prostasin
土壤微生物影响植物可塑性的生态和进化	Bolin, L. G.	PDF	N/A	Soil microbes influence the ecology and evolution of plant plasticity
基因和系统基因组的不一致揭示了温带Loliinae草本植物中的冲突杂交事件	Moreno-Aguilar, M. F.	PDF	N/A	Genic and phylogenomic discordances reveal conflicting hybridization episodes in temperate Loliinae grasses
欧洲小麦白粉病的群体基因组学与分子流行病学研究	Jigisha, J.	PDF	N/A	Population genomics and molecular epidemiology of wheat powdery mildew in Europe
酵母细胞裂解突变体cly8是ESP1的一个温度敏感等位基因。	Putnam, C. D.	PDF	N/A	The Saccharomyces cerevisiae cell lysis mutant cly8 is a temperature-sensitive allele of ESP1
人鼠蛋白质组学揭示了阿尔茨海默病与淀粉体中蛋白质周转延迟的共同通路	Yarbro, J. M.	PDF	N/A	Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome
EpigeneticAgePipeline：一个用于从甲基化微阵列全面评估表观遗传年龄指标的R包	Rayevskiy, S.	PDF	N/A	EpigeneticAgePipeline: an R package for comprehensive assessment of epigenetic age metrics from methylation microarrays
重建过去的插入缺失的算法：仅删除的简约性问题	Moutet, J.	PDF	N/A	Algorithms to reconstruct past indels: the deletion-only parsimony problem
胶质母细胞瘤化疗耐药性的获得和逆转是由Rho GTPase通路介导的。	Magalhaes, Y. T.	PDF	N/A	Acquisition and reversal of glioblastoma chemoresistance are mediated by the Rho GTPase pathway
CHK1介导的TOP1催化活性调控抑制了复制和转录相关的基因组不稳定性	Majumdar, A. G.	PDF	N/A	CHK1-mediated regulation of TOP1 catalytic activity suppresses replication and transcription-associated genomic instability
体内表达与SCA27A相关的FGF14突变会导致半合子不足及小脑浦肯野神经元放电受损	Ransdell, J. L.	PDF	N/A	In Vivo Expression of an SCA27A-linked FGF14 Mutation Results in Haploinsufficiency and Impaired Firing of Cerebellar Purkinje Neurons
可分离的默认模式网络连接模式构成了精神病风险中不同症状的基础	Ajunwa, C. C.	PDF	N/A	Dissociable Default Mode Network Connectivity Patterns Underlie Distinct Symptoms in Psychosis Risk
听觉工作记忆在音乐能力与听觉流分离之间的关系中起中介作用。	Liu, M.	PDF	N/A	Auditory working memory mediates the relationship between musicianship and auditory stream segregation
F-BAR蛋白CIP4和FBP17在皮层神经元的径向迁移和突起生长中发挥作用。	English, L. A.	PDF	N/A	F-BAR proteins CIP4 and FBP17 function in cortical neuron radial migration and process outgrowth
前脑岛中的多巴胺传递塑造了焦虑的神经编码	COUDERC, Y.	PDF	N/A	Dopamine transmission in the anterior insula shapes the neural coding of anxiety
# BioRxiv 2024-10-24 Papers

标题	作者	PDF链接	代码仓库	Title
基于映射的基因组大小估计	Natarajan, S.	PDF	N/A	Mapping-based genome size estimation
恶性疟原虫配子体的数量和比例从急性感染到慢性寄生虫携带状态有所不同，尽管性成熟率保持不变。	van Dijk, H.	PDF	N/A	Number and proportion of P. falciparum gametocytes vary from acute infection to chronic parasite carriage despite unaltered sexual commitment rate
果蝇鞘神经胶质细胞、星形胶质细胞和神经元中的睡眠、进食和代谢稳态动力学	Flores-Valle, A.	PDF	N/A	Dynamics of sleep, feeding, and metabolic homeostasis in Drosophila ensheathing glia, astrocytes, and neurons
非经典端粒酶逆转录酶通过STAT5调控主动脉瓣细胞的成骨性重编程	Cuevas, R. A.	PDF	N/A	Non-canonical Telomerase Reverse Transcriptase Controls Osteogenic Reprogramming of Aortic Valve Cells Through STAT5
砍伐改变了热带森林的结构，而将其转化为农业用地则降低了生物多样性和生态功能。	Marsh, C. J.	PDF	N/A	Logging alters tropical forest structure, while conversion to agriculture reduces biodiversity and functioning
建模信心判断停止规则中的速度-准确性权衡	Herregods, S.	PDF	N/A	Modelling Speed-Accuracy Tradeoffs in the Stopping Rule for Confidence Judgments
撤回：纳米盘重构的大肠杆菌趋氧受体中的信号转导与激酶调控	Maschmann, Z. A.	PDF	N/A	WITHDRAWN: Signal Transduction and Kinase Control in Nanodisc Reconstituted E. coli Aerotaxis Receptor
深度主动学习在生物医学分割中的鲁棒性	Arikan, M.	PDF	N/A	Deep Active Learning for Robust Biomedical Segmentation
利用新的数据资源来定义新型隐球菌对环境信号的反应	Kang, Y. S.	PDF	N/A	Leveraging a new data resource to define the response of C. neoformans to environmental signals
从单个解剖学上共定位的细胞重建库中提取近似连接组的方法	Manjunatha, K. K. H.	PDF	N/A	A method for extracting an approximated connectome from libraries of single anatomically co-registered cell reconstructions
通过数据驱动的标度律解码朊病毒样结构域的相分离	Maristany, M. J.	PDF	N/A	Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
骨形态发生蛋白信号通路中的突变使斑马鱼和人类对乙醇诱导的下颌畸形更为敏感	Klem, J. R.	PDF	N/A	Mutation in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations
原位近原子分辨率下的核糖体动态快照：全面洞察真核延伸循环	Zhang, X.	PDF	N/A	Snapshots of ribosome dynamics near atomic-resolution in situ: full insight into the eukaryotic elongation cycle
ATR通过从头胆固醇合成促进mTORC1活性。	Tangudu, N. K.	PDF	N/A	ATR promotes mTORC1 activity via de novo cholesterol synthesis
可修改的临床牙科印模方法，用于从脊椎动物获取全口及详细的牙齿特征	Wibisana, J. N.	PDF	N/A	Modifiable clinical dental impression methods to obtain whole-mouth and detailed dental traits from vertebrates
KRAB锌指基因和转座元件的调控网络在人类大脑进化和疾病过程中发生了变化	Chen, Y.-C.	PDF	N/A	Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease
山松甲虫在不同寄主抗性的森林中蔓延	Brush, M.	PDF	N/A	Mountain pine beetle spread in forests with varying host resistance
微生介导入侵的统一理论	Martignoni, M. M.	PDF	N/A	Toward a unified theory of microbially-mediated invasion
成本效益权衡在练习过程中调节了基于规则到基于记忆的处理转变	Yang, G.	PDF	N/A	Cost-benefit Tradeoff Mediates the Rule- to Memory-based Processing Transition during Practice
可泛化的情感投入和脱离神经模型	Nanni Zepeda, M.	PDF	N/A	Generalizable Neural Models of Emotional Engagement and Disengagement
SEGUID v2：扩展SEGUID校验和以适用于环状、线性、单链和双链生物序列	Pereira, H.	PDF	N/A	SEGUID v2: Extending SEGUID checksums for circular, linear, single- and double-stranded biological sequences
mm2-gb：用于长读DNA比对的GPU加速Minimap2	Dong, J.	PDF	N/A	mm2-gb: GPU Accelerated Minimap2 for Long Read DNA Mapping
作为进化驱动力的可移动元件在仙人掌嗜好果蝇物种宿主转移中的作用	Oliveira, D. S. d.	PDF	N/A	Transposable elements as evolutionary driving force to host shift in cactophilic Drosophila species
在V1皮层柱模型中，细胞类型的特定放电模式取决于前馈和反馈驱动状态。	Moreni, G.	PDF	N/A	Cell type specific firing patterns in a V1 cortical column model depend on feedforward and feedback-driven states
氨基酸招募进入遗传密码的顺序由最后普遍共同祖先的蛋白质域解析	Wehbi, S.	PDF	N/A	Order of amino acid recruitment into the genetic code resolved by Last Universal Common Ancestor's protein domains
5-HT1A受体在斑马鱼对潜在威胁的反应及社交性中的作用	de Sousa, L. V. X. B.	PDF	N/A	Roles of the 5-HT1A receptor in zebrafish responses to potential threat and in sociality
羽纹硅藻中细胞大小感知和接合型分化的分子指纹	Belisova, D.	PDF	N/A	Molecular fingerprints of cell size sensing and mating type differentiation in pennate diatoms
栖息地破碎化介导了长期气候驱动下鸟类喜温性变化的机制	Liu, J.	PDF	N/A	Habitat fragmentation mediates the mechanisms underlying long-term climate-driven thermophilization in birds
铁死亡抑制对抗代谢紊乱并改善肺动脉环扎猪的心脏功能	Kazmirczak, F.	PDF	N/A	Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs
发现荧光：利用社区科学记录新型生物荧光现象，并促进社区参与科学活动	Burke, H.	PDF	N/A	Finding Fluorescence: Utilizing community science to document novel biofluorescence occurrences and encourage community engagement in science
通过神经反馈实现对远程海马表征的闭环调制	Coulter, M. E.	PDF	N/A	Closed-loop modulation of remote hippocampal representations with neurofeedback
在阿尔茨海默病的小鼠模型中，微生物群以性别特异性的方式影响免疫反应。	Bostick, J. W.	PDF	N/A	The microbiome shapes immunity in a sex-specific manner in mouse models of Alzheimer's disease
阿尔茨海默病相关保护性变异Plcg2-P522R以性别二态性方式调节外周巨噬细胞功能	Staley, H. A.	PDF	N/A	Alzheimer's disease-associated protective variant Plcg2-P522R modulates peripheral macrophage function in a sex-dimorphic manner
针对动物体内特定基因组DNA序列的靶向诱变，以生成体内变异文库	Falo-Sanjuan, J.	PDF	N/A	Targeted mutagenesis of specific genomic DNA sequences in animals for the in vivo generation of variant libraries
17α-雌二醇治疗对内分泌系统的影响通过下丘脑单核转录组测序揭示	Li, L.	PDF	N/A	The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus
AIVE：通过全面分析准确预测SARS-CoV-2感染性	Park, J.	PDF	N/A	AIVE: accurate predictions of SARS-CoV-2 infectivity from comprehensive analysis
小鼠大脑的左右脑神经解剖学广泛不对称性	Silberfeld, A.	PDF	N/A	Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain
西欧沿海沙丘中植物相关无脊椎动物群落结构的驱动因素	Van De Walle, R.	PDF	N/A	Drivers of plant-associated invertebrate community structure in West-European coastal dunes
全组织成像：亚微米分辨率下的细胞边界成像用于自动细胞分割——在外胚层附属物上皮弯曲中的应用	Norris, S. C. P.	PDF	N/A	Whole Tissue Imaging of Cellular Boundaries at Sub-Micron Resolutions for Automatic Cell Segmentation: Applications in Epithelial Bending of Ectodermal Appendages
不平衡基因组中RNA m6A甲基化的动态变化及其调控作用	Zhang, S.	PDF	N/A	Dynamics and Regulatory Roles of RNA m6A Methylation in Unbalanced Genomes
胶质细胞调控嗅觉关键期中的经验依赖性可塑性	Leier, H. C.	PDF	N/A	Glia control experience-dependent plasticity in an olfactory critical period
人类目标导向动作的准备涉及皮质脊髓神经计算的混合。	Wadsley, C. G.	PDF	N/A	Goal-directed action preparation in humans entails a mixture of corticospinal neural computations
一种能够穿过血脑屏障的神经肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了具有抗惊厥、神经保护和抗炎特性的药理性低体温。	Ferhat, L.	PDF	N/A	A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
运动序列特异性学习诱导的皮层脊髓可塑性偏向于感觉运动μ节律的峰值相位	Suresh, T.	PDF	N/A	Motor sequence-specific learning-induced corticospinal plasticity is biased towards sensorimotor mu rhythm peak phases
自我关联通过自动优先处理社会显著信号来增强早期注意力选择	Scheller, M.	PDF	N/A	Self-association enhances early attentional selection through automatic prioritization of socially salient signals
基于新型扩增子的方法用于HIV-1 M组重组形式近全长基因组（NFLG）测序	Moscona, R.	PDF	N/A	Novel Amplicons based Method for Near-Full-Length Genome (NFLG) Sequencing of HIV-1 Group M Recombinant Forms
一种基于原则的区域间皮层网络社区检测方法	Armas, J. S. M.	PDF	N/A	A principled approach to community detection in interareal cortical networks
使用泛基因组进行基因型序列解析的拷贝数变异，揭示了重复基因的同源特异性全球多样性及表达分化	Ma, W.	PDF	N/A	Genotyping sequence-resolved copy-number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes
通过多模态蛋白质-配体对比学习提升挑战性目标筛选	Wang, Z.	PDF	N/A	Enhancing Challenging Target Screening via Multimodal Protein-Ligand Contrastive Learning
神经扫描：通过解剖网络的时空整合探索神经发育	Koonce, N. L.	PDF	N/A	NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks
UBE3C和NRF1依赖的蛋白酶体途径对急性蛋白质聚集物周转的时间控制	Hickey, K. L.	PDF	N/A	Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways
灵长类尾状核在多模态决策中的独特神经结构及其关键作用	ZENG, Z.	PDF	N/A	Distinct neural manifolds and critical roles of primate caudate nucleus in multimodal decision-making
SARS-CoV-2主蛋白酶活性位点环的构象空间由配体结合和蛋白质间别构效应决定。	Lee, E.	PDF	N/A	The Conformational Space of the SARS-CoV-2 Main Protease Active Site Loops is Determined by Ligand Binding and Interprotomer Allostery
在发声新颖性的进化过程中，运动皮层投射的选择性扩展	Isko, E. C.	PDF	N/A	Selective expansion of motor cortical projections in the evolution of vocal novelty
免疫样糖识别与横向获得性糖加工协同调控微生物内共生中的宿主控制	Jenkins, B. H.	PDF	N/A	Immune-like glycan-sensing and horizontally-acquired glycan-processing orchestrate host control in a microbial endosymbiosis
制造感知的生成模型架构能够实现生物序列的设计和合成，达到千万亿次规模	Weinstein, E. N.	PDF	N/A	Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale
解析铜绿假单胞菌对亚胺培南耐药性的蛋白质组学图谱：临床与对照菌株的比较研究	Eidsaa, M.	PDF	N/A	Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains
母体脂联素恢复了暴露于宫内母体肥胖的成年后代阻力血管中的胆碱能血管舒张	Murphy, M.	PDF	N/A	Maternal adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero
反复的基因渐渗和地理分层塑造了新热带地区的酿酒酵母（Saccharomyces cerevisiae）	Avelar-Rivas, J. A.	PDF	N/A	Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics
尾洛辛介导的软腐欧氏杆菌属细菌间的相互作用	Borowicz, M.	PDF	N/A	Tailocin-mediated interactions in Soft Rot Pectobacteriaceae
一项简单的措施可减少高脂肪饮食摄入并降低小鼠肥胖率	Barrett, M. R.	PDF	N/A	A simple action reduces high fat diet intake and obesity in mice
对古老干燥样本中的RNA进行测序，揭示了过去的病毒群以及长期存活的RNA的特性。	Keene, A. H.	PDF	N/A	Sequencing RNA from old, dried specimens reveals past viromes and properties of long-surviving RNA
生物膜流丝的应力硬化行为	Savorana, G.	PDF	N/A	Stress-hardening behaviour of biofilm streamers
重新审视雄蚊不吸血的范式	Bozic, J.	PDF	N/A	Revisiting the paradigm of anhematophagy in male mosquitoes
纳米抗体表位预测中的AI驱动方法：我们是否已经到达？	Eshak, F.	PDF	N/A	AI driven approaches in Nanobody Epitope Prediction: Are We There Yet?
探索用于抗体序列设计排名的对数似然评分	Ucar, T.	PDF	N/A	Exploring Log-Likelihood Scores for Ranking Antibody Sequence Designs
焦虑/抑郁的个体在认知冲突编码过程中表现出前额叶-颞叶同步性中断。	Shekara, A.	PDF	N/A	Anxious/depressed individuals exhibit disrupted frontotemporal synchrony during cognitive conflict encoding
Dnajc3（HSP40）调节小鼠视神经的轴突再生	Wang, J.	PDF	N/A	Dnajc3 (HSP40) Modulates Axon Regeneration in the Mouse Optic Nerve
通过基因集嵌入揭示潜在的生物功能关联	Huang, Y.	PDF	N/A	Uncovering Latent Biological Function Associations through Gene Set Embeddings
保留隐藏的层次结构：用于增强基因组序列分析的庞加莱距离	Ali, S.	PDF	N/A	Preserving Hidden Hierarchical Structure: Poincare Distance for Enhanced Genomic Sequence Analysis
半监督组学因子分析（SOFA）从多组学数据中的潜在因子中分离出已知的变异来源。	Capraz, T.	PDF	N/A	Semi-supervised Omics Factor Analysis (SOFA) disentangles known sources of variation from latent factors in multi-omics data
增强小鼠发声的皮层运动神经元投射	Boyd, J. L.	PDF	N/A	Enhancing cortico-motoneuronal projections for vocalization in mice
有丝分裂纺锤体的方向和动力学通过NuMA定位在各向异性组织拉伸的精细调节下得以实现。	Tarannum, N.	PDF	N/A	Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation
青光眼视网膜神经节细胞（RGC）死亡与眼压（IOP）诱导的血视网膜屏障破坏有关。	Zhang, C.	PDF	N/A	IOP-induced blood-retinal barrier compromise contributes to RGC death in glaucoma
B细胞表达的酶PexRAP，作为醚脂生物合成中的中间体，促进了抗体反应和生发中心的大小。	Cho, S. H.	PDF	N/A	B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
在异种Caenorhabditis胚胎的单细胞阶段出现了杂交不亲和性。	Bloom, J.	PDF	N/A	Hybrid incompatibility emerges at the one-cell stage in interspecies Caenorhabditis embryos
尖峰皮层及其连接网络中的结构妥协	Sahlas, E.	PDF	N/A	Structural compromise in spiking cortex and connected networks
地球上最古老生物潘多中的体细胞突变镶嵌图	Pineau, R.	PDF	N/A	Mosaic of Somatic Mutations in Earth's Oldest Living Organism, Pando
Rag2Mol：基于检索增强生成的结构化药物设计	Zhang, P.-D.	PDF	N/A	Rag2Mol: Structure-based drug design based on Retrieval Augmented Generation
基底神经节输出的计算瓶颈（以及应对方法）	Humphries, M. D.	PDF	N/A	The computational bottleneck of basal ganglia output (and what to do about it)
α-突触核蛋白株系动力学与帕金森病中的认知转变相关	Gadhave, K.	PDF	N/A	α-Synuclein Strain Dynamics Correlate with Cognitive Shifts in Parkinson's Disease
蚊虫调查揭示了马拉维蚊子在桑给巴尔市繁殖地点的偏好。	Hill, K.	PDF	N/A	Larval surveys reveal breeding site preferences of malaria vector Anopheles spp. in Zanzibar City
丹曲林对携带严重恶性高热突变Y522S的雷诺定受体1的抑制作用通过冷冻电镜可视化	Iyer, K. A.	PDF	N/A	Dantrolene inhibition of ryanodine receptor 1 carrying the severe malignant hyperthermia mutation Y522S visualized by cryo-EM
PACT通过防止内源性双链RNA异常激活PKR，而无需隔离。	Ahmad, S.	PDF	N/A	PACT prevents aberrant activation of PKR by endogenous dsRNA without sequestration
依赖于HuR的RyR2表达有助于棕色脂肪细胞中钙介导的产热作用	Guarnieri, A. R.	PDF	N/A	HuR-dependent expression of RyR2 contributes to calcium-mediated thermogenesis in brown adipocytes
入侵太阳珊瑚（Tubastrea spp.）在里约热内卢海岸的模拟幼虫扩散：亚中尺度丝状体在离岸运输和连通性中的作用	Calado, L.	PDF	N/A	Simulated larvae dispersion of the invasive sun-coral (Tubastrea spp.) along Rio de Janeiro's coast: the role of submesoscale filaments on offshore transport and connectivity
在早更新世到中更新世过渡期间，人类经历了严重瓶颈的证据不足。	Durvasula, A.	PDF	N/A	Insufficient evidence for a severe bottleneck in humans during the Early to Middle Pleistocene transition
利用自然序列变异在胚胎发生过程中情境化转录因子结合	Sigalova, O. M.	PDF	N/A	Contextualising transcription factor binding during embryogenesis using natural sequence variation
低保真度DNA聚合酶IV加速了铜绿假单胞菌的基因组进化	Castell, S.	PDF	N/A	Low fidelity DNA polymerase IV accelerates genome evolution in Pseudomonas aeruginosa
用于研究RNA结构的生物正交环丙烯酮	Chen, S.	PDF	N/A	Bioorthogonal cyclopropenones for investigating RNA structure
人类肠道共生菌阿利斯蒂普斯·蒂莫内西斯（Alistipes timonensis）能够调节宿主的脂质组，并向宿主传递抗炎的外膜囊泡，从而在白介素10缺陷的小鼠模型中抑制结肠炎。	Older, E. A.	PDF	N/A	Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model
II型-B CRISPR-Cas增强特异性的机制	Hibshman, G. N.	PDF	N/A	Mechanism of type II-B CRISPR-Cas enhanced specificity
对于植物来说真实的情况，对于三角褐指藻（Phaeodactylum tricornutum）可能并不适用：香草兰（Vanilla planifolia）的香草醛合成酶（VpVAN）被靶向到硅藻的四个亚细胞区室中的情况。	Diaz-Garza, A. M.	PDF	N/A	What is true for plants may not be true for Phaeodactylum tricornutum: The case of Vanilla planifolia vanillin synthase (VpVAN) targeted to four subcellular compartments of the diatom.
裸盖菇素减少了SAPAP3基因敲除小鼠模型中强迫行为的梳理行为	Gattuso, J. J.	PDF	N/A	Psilocybin Reduces Grooming in the SAPAP3 Knockout Mouse Model of Compulsive Behaviour
语言网络历久弥新：老年人脑中保留的选择性、侧化及网络内功能同步性	Billot, A.	PDF	N/A	The language network ages well: Preserved selectivity, lateralization, and within-network functional synchronization in older brains
鉴定细胞周期蛋白L1作为调控乙型肝炎病毒复制的宿主因子	Owino, C. O.	PDF	N/A	Identification of Cyclin L1 as a host factor regulating Hepatitis B Virus replication
结核菌噬菌体毒力比较研究	Rubino, I.	PDF	N/A	Comparative study on the virulence of mycobacteriophages
比较基因组分析揭示了水体中拉氏菌属（Ralstonia spp.）致病性的降低	Liu, g.	PDF	N/A	Comparative genomic analysis reveals reduced pathogenicity of Ralstonia spp. in water
SETD2促进PAF1C与延伸中的RNA聚合酶II的相互作用，并且对于神经分化是必需的。	Ambrosi, C.	PDF	N/A	SETD2 promotes PAF1C interactions with the elongating RNA Pol II and is required for neuronal differentiation
RTL4是一种与自闭症谱系障碍相关的逆转录病毒衍生基因，是一种微胶质细胞基因，在出生后的大脑中对去甲肾上腺素产生反应。	Ishino, F.	PDF	N/A	RTL4, a retrovirus-derived gene implicated in autism spectrum disorder, is a microglial gene that responds to noradrenaline in the postnatal brain
RTL4是一种与自闭症谱系障碍相关的逆转录病毒衍生基因，是一种对出生后大脑中的去甲肾上腺素产生反应的微胶质细胞基因。	Ishino, F.	PDF	N/A	RTL4, a retrovirus-derived gene implicated in autism spectrum disorder, is a microglial gene that responds to noradrenaline in the postnatal brain
四棘刺鱼（Apeltes quadracus）具有XY性染色体系统，其X和Y染色体上均存在多态性倒位。	Liu, Z.	PDF	N/A	The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes
使用分层变压器进行机制性的基因型-表型转换	Lee, I.	PDF	N/A	Mechanistic genotype-phenotype translation using hierarchical transformers
LUNAR：一种利用综合基因组和临床数据预测胶质瘤复发的深度学习模型	Patricoski-Chavez, J. A.	PDF	N/A	LUNAR: A Deep Learning Model to Predict Glioma Recurrence Using Integrated Genomic and Clinical Data
进化中新出现的脑结构的可变存在与特质冲动性相关	Willbrand, E. H.	PDF	N/A	Variable Presence of an Evolutionarily New Brain Structure is Related to Trait Impulsivity
表示相似性分析、中心核对齐和典型相关分析之间的等价性	Williams, A. H.	PDF	N/A	Equivalence between representational similarity analysis, centered kernel alignment, and canonical correlations analysis
BBSome亚基耗竭通过TGF-β信号通路改变受体内吞作用并促进上皮-间质转化	Solarat, C.	PDF	N/A	Depletion of BBSome Subunits Alters Receptor Endocytosis and Promotes EMT via TGF-β Signaling
尿液生化生态学揭示了微生物组-代谢物相互作用和复发性尿路感染的代谢标志物	Neugent, M. L.	PDF	N/A	Urinary biochemical ecology reveals microbiome-metabolite interactions and metabolic markers of recurrent urinary tract infection
毒力因子与信号分子的相互作用：白蛋白和钙介导的支气管败血博德特菌生物膜调控	Mugni, S. L.	PDF	N/A	Interplay of Virulence Factors and Signaling Molecules: Albumin and Calcium-Mediated Biofilm Regulation in Bordetella bronchiseptica
丰富的环境需要对海马旁神经网进行重塑，以在阿尔茨海默病小鼠模型中触发记忆改善	Bouisset, G.	PDF	N/A	Enriched environment requires remodeling of hippocampal perineuronal nets to trigger memory improvement in Alzheimer's mouse model
冲动的青少年在解码面部表情情绪时表现出处理效率低下和决策阈值较低的特点。	Schreiber, A. M.	PDF	N/A	Impulsive adolescents exhibit inefficient processing and a low decision threshold when decoding facial expressions of emotions
新的治疗组合，以增强针对胶质母细胞瘤细胞中EGFR的抗体和核酸适体的内吞作用	Cruz Da Silva, E.	PDF	N/A	New therapeutic combination to enhance endocytosis of antibodies and nucleic-acid aptamers targeting EGFR in glioblastoma cells
NINJ1在溶细胞死亡期间通过钙驱动的质膜脂质混杂而被激活。	Borges, J. P.	PDF	N/A	NINJ1 is activated by calcium-driven plasma membrane lipid scrambling during lytic cell death
Nance-Horan综合征样1通过与内皮素和Ena/VASP蛋白相互作用，促进快速内皮素介导的内吞作用。	Cope, J. F. W.	PDF	N/A	Nance-Horan Syndrome-like 1 interacts with endophilin and Ena/VASP proteins to promote fast endophilin-mediated endocytosis.
Nance-Horan综合征样1与内菲林和Ena/VASP蛋白相互作用，促进快速内菲林介导的内吞作用。	Cope, J. F. W.	PDF	N/A	Nance-Horan Syndrome-like 1 interacts with endophilin and Ena/VASP proteins to promote fast endophilin-mediated endocytosis.
极端干旱期间的进化救援	Anstett, D. N.	PDF	N/A	Evolutionary rescue during extreme drought
Pipeasm：一种用于自动化大型染色体规模基因组组装和评估的工具	Silva, B. M.	PDF	N/A	Pipeasm: a tool for automated large chromosome-scale genome assembly and evaluation
E3泛素连接酶NEDD4L通过降解PRMT5来抑制AKT/mTOR信号通路，从而防止结直肠癌肝转移。	Dong, Z.	PDF	N/A	The E3 ligase NEDD4L prevents colorectal cancer liver metastasis via degradation of PRMT5 to inhibit the AKT/mTOR signaling pathway
身体不满塑造了时间感知与内感受的相互作用	Rusinova, A.	PDF	N/A	Body dissatisfaction shapes time perception and interoception interplay
基因变异的相互作用激活酵母中潜在的代谢途径	Sasikumar, S.	PDF	N/A	Interaction of Genetic Variants Activates Latent Metabolic Pathways in Yeast
组织适应性Tregs利用炎症信号促进肠道从治疗相关损伤中修复	Fischer, J. C.	PDF	N/A	Tissue-adapted Tregs harness inflammatory signals to promote intestinal repair from therapy-related injury
鸟类沿经线方向迁徙，以响应青藏高原隆升所导致的亚洲季风效应。	Zhang, W.	PDF	N/A	Birds migrate longitudinally in response to the resultant Asian monsoons of the Qinghai-Tibet Plateau uplift
快速寿命的脊椎动物宿主具有更高的蚊媒寄生虫传播潜力	Dahlin, K. J.- M.	PDF	N/A	Fast-lived Vertebrate Hosts Exhibit Higher Potential for Mosquito-borne Parasite Transmission
果蝇翅膀上的性选择目标	De Lisle, S. P.	PDF	N/A	Targets of sexual selection on the Drosophila wing
病原体启动改变了野生鸣禽宿主的传播潜力和传播能力预测因子	Leon, A. E.	PDF	N/A	Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species
双trxG/PcG蛋白ULTRAPETALA1调控H3K27me3，并直接增强POLYCOMB抑制复合物2的活性，以实现精细调控的生殖转换	Geshkovski, V.	PDF	N/A	The dual trxG/PcG protein ULTRAPETALA1 modulates H3K27me3 and directly enhances POLYCOMB REPRESSIVE COMPLEX 2 activity for fine-tuned reproductive transitions
Bur1驱动的G1到S期转变诱导了酵母检查点突变体的羟基脲敏感性	da Silva, S. C. R.	PDF	N/A	Bur1-driven G1-to-S phase transition induces hydroxyurea sensitivity in yeast checkpoint mutants
Hippo-vgll3信号可能通过不同的脂肪动态影响大西洋鲑鱼成熟年龄的性别差异。	Ahi, E. P.	PDF	N/A	Hippo-vgll3 signaling may contribute to sex differences in Atlantic salmon maturation age via contrasting adipose dynamics
许多实验室血吸虫种群中保留了丰富的遗传变异。	Jutzeler, K. S.	PDF	N/A	Abundant genetic variation is retained in many laboratory schistosome populations
查尔酮异构酶的自然变异定义了控制黑杨种群间生长变异的主要位点	Durufle, H.	PDF	N/A	Natural variation in chalcone isomerase defines a major locus controlling growth variation between Populus nigra populations
香烟烟雾成分对-苯醌对人红细胞结构与功能的影响	Yadav, N.	PDF	N/A	Effect of p-benzoquinone, a cigarette smoke-derived component, on the architecture and function of human RBC
工程化细菌微室壳中的受控酶货物装载	Tefft, N. M.	PDF	N/A	Controlled enzyme cargo loading in engineered bacterial microcompartment shells
麦角固醇和7-脱氢胆固醇及其内过氧化物的比较研究：生成、鉴定及其对磷脂膜和黑色素瘤细胞的影响	Yukuyama, M. N.	PDF	N/A	Comparative study of Ergosterol and 7-dehydrocholesterol and their Endoperoxides: Generation, Identification and Impact in Phospholipid Membranes and Melanoma Cells
ConvNTC：用于预测疾病相关miRNA对和细胞相关药物对的卷积神经张量补全	Liu, P.	PDF	N/A	ConvNTC: Convolutional neural tensor completion for predicting the disease-related miRNA pairs and cell-related drug pairs
揭示表位特异性TCR库的隐藏序列分布及其对机器学习模型性能的影响	Gielis, S.	PDF	N/A	Revealing the hidden sequence distribution of epitope-specific TCR repertoires and its influence on machine learning model performance
ProteoSeeker：一款功能丰富的宏基因组分析工具，用于便捷且全面的宏基因组探索	Filis, G.	PDF	N/A	ProteoSeeker: A Feature-Rich Metagenomic Analysis Tool for Accessible and Comprehensive Metagenomic Exploration
通过互补的综合结构生物学方法解析GPCR-G蛋白受体相互作用的分子决定因素	Castel, J.	PDF	N/A	Deciphering molecular determinants of GPCR-G protein receptor interactions by complementary integrative structural biology methods
多聚磷酸盐比DNA更有效地区分蛋白质构象系综，促进多样化的组装和成熟行为。	Goyal, S.	PDF	N/A	Polyphosphate Discriminates Protein Conformational Ensembles More Efficiently than DNA Promoting Diverse Assembly and Maturation Behaviors
时空谱系追踪揭示了肿瘤生长和转移的动态空间结构	Jones, M. G.	PDF	N/A	Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis
周期素G相关激酶（GAK）是一种新型的有丝分裂激酶，也是弥漫性大B细胞淋巴瘤的治疗靶点。	Lightfuss, O. B.	PDF	N/A	The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma
NSD2通过整合素/FAK/AKT信号传导促进细胞硬度趋向性，并驱动从多囊肾病向囊性肾细胞癌的转变	Feng, W.	PDF	N/A	NSD2 promotes cell durotaxis and drives the transition from PKD to tubulocystic renal cell carcinoma through integrin/FAK/AKT signaling
抑制肿瘤相关巨噬细胞中的PIM激酶可抑制炎症小体1的激活，并增强前列腺癌对免疫治疗的敏感性。	Clements, A. N.	PDF	N/A	Inhibition of PIM kinase in tumor associated macrophages suppresses inflammasome 1 activation and sensitizes prostate cancer to immunotherapy
富集于突触信号传导的转录模式与高级别浆液性卵巢癌患者较短的生存期相关	Bhattacharya, A.	PDF	N/A	Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer
高级别浆液性卵巢癌中肿瘤-免疫动态的时间模型	Egan, D.	PDF	N/A	A TEMPORAL MODEL OF TUMOR-IMMUNE DYNAMICS IN HIGH GRADE SEROUS OVARIAN CANCER
羟基聚乙二醇：一种有效规避人体预存抗PEG抗体的解决方案，以实现高效递送	Ding, T.	PDF	N/A	Hydroxy polyethylene glycol: a solution to evade human pre-existing anti-PEG antibodies for efficient delivery
血压变异性损害中年小鼠的血管功能	Mendiola, P. J.	PDF	N/A	Blood pressure variability compromises vascular function in middle-aged mice
有氧能力与运动通过增强胆汁酸代谢来介导对肝脏脂肪变性的保护作用。	Kugler, B. A.	PDF	N/A	Aerobic capacity and exercise mediate protection against hepatic steatosis via enhanced bile acid metabolism.
从转录组数据驱动的布尔网络推断以预测细胞分化与重编程	Chevalier, S.	PDF	N/A	Data-driven inference of Boolean networks from transcriptomes to predict cellular differentiation and reprogramming
通过单细胞RNA测序解析强直性脊柱炎中的代谢途径及蛋白质相互作用网络	Yarici, M.	PDF	N/A	Deciphering Metabolic Pathways and Protein-Protein Interaction Networks in Ankylosing Spondylitis through Single-Cell RNA Sequencing
基于核滤波的自适应控制器在网络遗传学应用中的应用	Smart, B. C.	PDF	N/A	Kernel Filter-Based Adaptive Controllers For Cybergenetics Applications
口服耐受的系统效应改善了身体不同部位多个和同时发生的伤口的愈合	Nobrega, I. B. C.	PDF	N/A	Systemic effects of oral tolerance improve the healing of several and concomitant wounds in different body parts
维生素E补充剂可防止老年小鼠圆形精子细胞发生铁死亡	Germeraad, J.	PDF	N/A	Vitamin E supplementation prevents ferroptosis in round spermatids of aged mice
RDAforest：识别多基因适应的环境驱动因素。	Matz, M. V.	PDF	N/A	RDAforest: identifying environmental drivers of polygenic adaptation.
解析遗传性和可塑性对弗里蒙特杨树叶反射率在温度梯度上的影响	Seeley, M. M.	PDF	N/A	Disentangling the effect of heritability and plasticity on Populus fremontii leaf reflectance across a temperature gradient
CADET：利用eQTL汇总数据在混合样本中增强转录组范围的关联分析	Head, S. T.	PDF	N/A	CADET: Enhanced transcriptome-wide association analyses in admixed samples using eQTL summary data
GL15与FDL1之间的遗传相互作用调节了玉米幼苗角质层的沉积和叶片通透性	Castorina, G.	PDF	N/A	Genetic interaction between GL15 and FDL1 modulates juvenile cuticle deposition and leaf permeability in maize
猕猴桃病原菌丁香假单胞菌猕猴桃致病变种3型的基因组生物监测揭示了其在新西兰果园中对选择压力的适应性	Hemara, L. M.	PDF	N/A	Genomic biosurveillance of the kiwifruit pathogen Pseudomonas syringae pv. actinidiae biovar 3 reveals adaptation to selective pressures in New Zealand orchards
估计并纠正单细胞RNA测序数据中的索引跳跃误分配	Miao, L.	PDF	N/A	Estimating and correcting index hopping misassignments in single-cell RNA-seq data
5-氟尿嘧啶处理下人细胞培养中RNA修饰的时间定位	Berg, M.	PDF	N/A	Temporal placement of RNA modifications under 5-fluorouracil treatment in human cell culture
四个结构区域的流动性驱动植物LPOR的同工型特异性	Gabruk, M.	PDF	N/A	Mobility of Four Structural Regions Drives Isoform-Specific Properties of Plant LPOR
发育中的哺乳动物视网膜中机械性能的尺度不变性	Shelton, E. R.	PDF	N/A	Scale invariance of mechanical properties in the developing mammalian retina
通过信号分解和多尺度注意力克服分辨率增强Hi-C数据中的人工结构	Li, Q.	PDF	N/A	Overcoming artificial structures in resolution-enhanced Hi-C data by signal decomposition and multi-scale attention
优化神经诱导中的信息传递限制了海鞘胚胎的细胞表面接触	Bettoni, R.	PDF	N/A	Optimizing information transmission in neural induction constrains cell surface contacts of ascidian embryos
通过聚合物建模探索早衰症中的核纤层结构与解离	Hameed, H. A.	PDF	N/A	Exploring Nuclear Lamina Structure and Lamin Dissociation in Progeria through Polymer Modeling
PolSpec：基于偏振的光谱分类检测方法	Liu, H.	PDF	N/A	PolSpec: polarisation-based detection for spectral classification of optical signals
结构鉴定出RyR1的RY12域为ADP传感器，并作为恶性高热治疗药物丹曲林的目标	Kim, K.	PDF	N/A	Structural identification of the RY12 domain of RyR1 as an ADP sensor and the target of the malignant hyperthermia therapeutic dantrolene
3D-UHU-TU：健康尿路上皮环境中的三维膀胱癌模型	Murray, B. O.	PDF	N/A	3D-UHU-TU: A Three-Dimensional Bladder Cancer Model in a Healthy Urothelial Environment
线粒体功能障碍与内质网应激在人神经母细胞瘤SH-SY5Y细胞中CB1受体拮抗剂诱导的细胞凋亡中的作用	Mori, K.	PDF	N/A	Mitochondrial Dysfunction and ER Stress in CB1 Receptor Antagonist-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells
基于成像质谱流式技术引导的多模态质谱成像的超分辨率单细胞空间代谢组学	Ozturk, E.	PDF	N/A	Super Resolved Single-Cell Spatial Metabolomics from Multimodal Mass Spectrometry Imaging guided by Imaging Mass Cytometry
首次记录入侵的黄蜂（Vespa velutina nigrithorax Buysson, 1905）和雕刻切叶蜂（Megachile sculpturalis Smith, 1853）在斯洛伐克的出现（膜翅目：胡蜂科和切叶蜂科）	Purkart, A.	PDF	N/A	First records of invasive Vespa velutina nigrithorax Buysson, 1905 (Hymenoptera: Vespidae) and Megachile sculpturalis Smith, 1853 (Hymenoptera: Megachilidae) in Slovakia
AEA对TAT处理的人星形胶质细胞的拮抗活性识别出炎症衰老通路	Duraikannu, D.	PDF	N/A	Antagonistic activity of AEA on TAT treated Human Astrocytes identify Inflammaging pathways
RBP4作为孤儿DR6的拮抗配体发挥功能	Kim, T.	PDF	N/A	RBP4 functions as an antagonistic ligand of orphan DR6
寄生虫物种多样性的维持：时空生态位分区和聚集促进物种共存	Ramesh, A.	PDF	N/A	Maintenance of parasite species diversity: Spatiotemporal niche partitioning and aggregation facilitate species coexistence
真菌孢子季节在美国因气候变化而提前了二十年	Wu, R.	PDF	N/A	Fungal spore seasons advanced across the US over two decades of climate change
全球范围内对敌害释放假说的检验揭示了本地植物和外来植物在食草行为上的相似模式	Galman, A.	PDF	N/A	Global test of the enemy release hypothesis reveals similar patterns of herbivory across native and non-native plants
利用大规模层次聚类分析表观基因组间的统计关系	Kim, A.	PDF	N/A	Statistical relationships across epigenomes using large-scale hierarchical clustering
单细胞分辨率DESI质谱成像通过10倍样品扩展	Xie, C.	PDF	N/A	Single-Cell Resolution DESI Mass Spectrometry Imaging through 10-Fold Sample Expansion
T细胞受体多样性、癌症与性别：来自30,000个TCRβ库的洞察	Zahid, H. J.	PDF	N/A	T Cell Receptor Diversity, Cancer and Sex: Insights from 30,000 TCRβ Repertoires
WRAD核心扰动损害了DNA复制的保真度，促进了胰腺癌中的免疫编辑	Citron, F.	PDF	N/A	WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer
通过FBXW11和CTNNB1热点突变的互斥激活Wnt/β-catenin信号传导驱动唾液腺基底细胞腺瘤的发生	Wong, K.	PDF	N/A	Activation of Wnt/β-catenin signalling by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary gland basal cell adenoma
建立和分子表征源自原发性中枢神经系统淋巴瘤患者的类器官	Li, S.	PDF	N/A	Establishment and Molecular Characterization of Patient-Derived Organoids for Primary Central Nervous System Lymphoma
EFP分析器：一款快速、准确且易于教学的程序，用于分析由诱导多能干细胞衍生心肌细胞产生的外场电位	Patel, N. P.	PDF	N/A	EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes
hsa-miR-9-5p 在早发型子痫前期合体滋养层来源的细胞外囊泡中高表达，损害了脑微血管内皮细胞的促血管生成能力。	Logenthiran, P. V.	PDF	N/A	hsa-miR-9-5p highly expressed in syncytiotrophoblast-derived extracellular vesicles from early-onset preeclampsia impairs cerebral microvascular endothelial cell pro-angiogenic capacity
T细胞表位图谱揭示了SARS-CoV-2蛋白质组中进化保守区域具有免疫优势。	Bozkus, C. C.	PDF	N/A	T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.
DNA复制和修复机制之间的冲突会促进革兰氏阳性细菌的细胞死亡。	Gaimster, H.	PDF	N/A	Conflicts between the DNA replication and repair machineries promote cell death in Gram-positive bacteria
毒力调节并增强B群链球菌中的CRISPR-Cas9免疫	Pastuszka, A.	PDF	N/A	Virulence regulates and boosts CRISPR-Cas9 immunity in Group B Streptococcus
FtsK 启动了在无 FtsZ 的沙眼衣原体中组装独特的分裂体复合物	Harpring, M.	PDF	N/A	FtsK Initiates the Assembly of a Unique Divisome Complex in the FtsZ-less Chlamydia trachomatis
SARS-CoV-2在动物园老虎、狮子和鬣狗体内的种群扩张、多样化和适应	Bashor, L.	PDF	N/A	SARS-CoV-2 within-host population expansion, diversification and adaptation in zoo tigers, lions and hyenas
通过完整组装揭示了不同小鼠亚种间端粒和着丝粒的结构多样性	Adams, D.	PDF	N/A	The structural diversity of telomeres and centromeres across mouse subspecies revealed by complete assemblies
双工PCR检测法用于确定肩突硬蜱（蜱螨目：硬蜱科）的性别及交配状态，该蜱是莱姆病病原体的传播媒介。	Ronai, I.	PDF	N/A	Duplex PCR assay to determine sex and mating status of Ixodes scapularis (Acari: Ixodidae), vector of the Lyme disease pathogen
去泛素化酶Rpn11作为一种变构泛素传感器，促进26S蛋白酶体与底物的结合。	Htet, Z. M.	PDF	N/A	The deubiquitinase Rpn11 functions as an allosteric ubiquitin sensor to promote substrate engagement by the 26S proteasome
多花黄精根氟代聚磷酸-糖苷（NU2）通过靶向DNA拓扑异构酶I抑制多重耐药细菌和单细胞寄生虫	CHAKRABORTY, A. K.	PDF	N/A	Suregada multiflora Root Fluro-PolyPhosphate-Glycoside (NU2) inhibits MDR Bacteria and Unicellular Parasites Targeting DNA Topoisomerase I
拓扑重排激活了HerA-DUF抗噬菌体防御系统	Rish, A. D.	PDF	N/A	Topological rearrangements activate the HerA-DUF anti-phage defense system
利用光控开关鞘氨醇实现鞘脂生物合成的光学调控	Kol, M.	PDF	N/A	Optical control of sphingolipid biosynthesis using photoswitchable sphingosines
从绿藻衣藻中高效分泌一种塑料降解酶	Molino, J. V. D.	PDF	N/A	Efficient secretion of a plastic degrading enzyme from the green algae Chlamydomonas reinhardtii
利用纳米抗体与抗原相互作用调控铁氧还蛋白电子传递	Truong, A.	PDF	N/A	Regulating ferredoxin electron transfer using nanobody and antigen interactions
基于CRISPRi的双功能逻辑门	Yao, Z.	PDF	N/A	Dual-function logic gates based on CRISPRi
阐明异黄酮合酶介导的酵母蛋白质-蛋白质相互作用在代谢中的作用	Liu, C.	PDF	N/A	Elucidating the metabolic roles of isoflavone synthase-mediated protein-protein interactions in yeast
用于单细胞分析的基因编码荧光条形码	Lu, X.	PDF	N/A	Genetically-Encoded Fluorescence Barcodes for Single-Cell Analysis
将邻近标记酶展示于细胞外囊泡表面用于表面组及靶细胞的定位	ZHENG, W.	PDF	N/A	Surface display of proximity labeling enzymes on extracellular vesicles for surfaceome and target cell mapping
I型干扰素诱导肝细胞中的GBPs和溶酶体防御，以控制疟疾	Marques-da-Silva, C.	PDF	N/A	Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malaria
构建用于研究HIV-1复制及甲基苯丙胺影响的巨噬细胞嗜性亚型C HIV-1-mGreenLantern报告病毒	Mofed, D.	PDF	N/A	Construction of a macrophage-tropic subtype C HIV-1-mGreenLantern reporter virus for studies on HIV-1 rep-lication and the impact of methamphetamine
脱氮微生物群落中协同作用的产生与破坏	Carr, A. V.	PDF	N/A	Emergence and disruption of cooperativity in a denitrifying microbial community
非芳香化酶依赖的雌激素生成：Wood-Ljungdahl途径可能对生物圈中雌激素的出现有所贡献。	Wang, P.-H.	PDF	N/A	Aromatase-independent estrogenesis: Wood-Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere
在土壤细菌向叶际过渡的早期阶段，确定性定殖现象便已出现，并受到植物与微生物相互作用的影响。	Mayer, T.	PDF	N/A	Deterministic colonization arises early during the transition of soil bacteria to the phyllosphere and is shaped by plant-microbe interactions.
共生菌和致病菌附着于肠上皮细胞的肠道定殖动力学	Rivera, D. E.	PDF	N/A	Dynamics of gut colonization by commensal and pathogenic bacteria that adhere to the intestinal epithelium
螺原体共生体减少宿主脂质合成及类Stomoxyn肽有助于舌蝇Glossina fuscipes抵抗锥虫	Awuoche, E. O.	PDF	N/A	Spiroplasma endosymbiont reduction of host lipid synthesis and Stomoxyn-like peptide contribute to trypanosome resistance in the tsetse fly Glossina fuscipes
利用新型遗传方法进行端粒酶RNA的转运	Kirk, K. E.	PDF	N/A	Trafficking of the Telomerase RNA using a Novel Genetic Approach
脑膜炎奈瑟菌B群荚膜多糖合成启动子的调控由HTH_XRE家族转录因子进行	Sofowora, I.	PDF	N/A	Regulation of the Promoter for Capsular Polysaccharide Synthesis in Neisseria Meningitidis Serogroup B by HTH_XRE Family Transcription Factor
TFAM作为UVC诱导的线粒体DNA损伤的传感器	King, D. E.	PDF	N/A	TFAM as a sensor of UVC-induced mitochondrial DNA damage
融合前稳定型疱疹病毒gB三聚体的计算设计	McCallum, M.	PDF	N/A	Computational design of prefusion-stabilized Herpesvirus gB trimers
植物中的铁与氧化还原感应：拟南芥BRUTUS和BRUTUS-LIKE2蛋白的蚯蚓血红蛋白样结构域特性	Pullin, J.	PDF	N/A	Iron and redox sensing in plants: properties of the hemerythrin-like domains of Arabidopsis BRUTUS and BRUTUS-LIKE2 proteins
机器学习辅助定向进化的多样化组合景观评估	Li, F.-Z.	PDF	N/A	Evaluation of Machine Learning-Assisted Directed Evolution Across Diverse Combinatorial Landscapes
一种跨动物和环境的普遍海马记忆编码	Wirtshafter, H. S.	PDF	N/A	A universal hippocampal memory code across animals and environments
GABA能神经元可以促进皮层扩散性去极化的传播：在小鼠新皮质切片中的实验以及一种新的神经场计算模型	Baspinar, E.	PDF	N/A	GABAergic neurons can facilitate the propagation of cortical spreading depolarization: experiments in mouse neocortical slices and a novel neural field computational model
皮质去甲肾上腺素-星形胶质细胞信号在介导习得行为中起关键作用	Drummond, G. T.	PDF	N/A	Cortical norepinephrine-astrocyte signaling critically mediates learned behavior
针对与严重儿童癫痫和早逝相关的胎儿期富集钾通道的基因治疗	Golinski, S.	PDF	N/A	Gene therapy for targeting a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death
大规模突触成像揭示了视觉皮层神经元的突触输入结构，无需反向传播的动作电位	Kondo, S.	PDF	N/A	Synaptic input architecture of visual cortical neurons revealed by large-scale synapse imaging without backpropagating action potentials
精神分裂症和健康个体在深部脑形态和不对称性方面存在性别差异：ENIGMA-精神分裂症工作组的元分析	Cimmino, D.	PDF	N/A	Sex differences in deep brain shape and asymmetry persist across schizophrenia and healthy individuals: A meta-analysis from the ENIGMA-Schizophrenia Working Group
树突图谱揭示纹状体D1/D2神经元形态的空间组织	Park, C. S.	PDF	N/A	Dendritome Mapping Unveils Spatial Organization of Striatal D1/D2-Neuron Morphology
TRAIL诱导caspase依赖性的网格蛋白介导的内吞作用机器特定组分的切割	Lawrence, D. A.	PDF	N/A	TRAIL induces caspase-dependent cleavage of specific components of the clathrin-mediated endocytosis machinery
# BioRxiv 2024-10-23 Papers

标题	作者	PDF链接	代码仓库	Title
脑岛和颞上沟在社会决策中对人际内疚感和责任感的贡献	Gaedeke, M.	PDF	N/A	Contributions of insula and superior temporal sulcus to interpersonal guilt and responsibility in social decisions
图像平衡是一种自下而上的神经美学属性，介导注意力和眼球运动。一个原始的视觉操作系统解释了平衡的属性，以及一种基本的视觉组织世界的方式。	Corwin, D. M.	PDF	N/A	Pictorial balance is a bottom-up neuro-aesthetic property mediating attention and eye movements. A primitive visual operating system explains the property of balance and a primary visual way of organizing the world.
清醒小鼠背侧下丘的噪声神经元群有效地编码声音定位	Boffi, J. C.	PDF	N/A	Noisy neuronal populations effectively encode sound localization in the dorsal inferior colliculus of awake mice
多巴胺神经元在果蝇的嗅觉记忆中具有不同的、急性的功能，这些功能驱动着吸引和厌恶行为。	Mohammad, F.	PDF	N/A	Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion
为什么棕色的鬼魂在夜晚鸣叫	Oboti, L.	PDF	N/A	Why the brown ghost chirps at night
通过过度产生cMYC蛋白在TP53和RB1缺失的肺神经内分泌细胞中形成恶性转移性小细胞肺癌，这些细胞源自人类胚胎干细胞	Chen, H.	PDF	N/A	FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS
面向界面的分子生成框架用于蛋白质-蛋白质相互作用调节剂	Wang, J.	PDF	N/A	Interface-aware molecular generative framework for protein-protein interaction modulators
Rab10通过维持钙稳态和蛋白质合成来调节神经肽的释放。	Dong, J.	PDF	N/A	Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis
简单寄生虫生命周期中的复杂相互作用塑造了其毒力的进化	Silva, L. M.	PDF	N/A	Complex interactions in the life cycle of a simple parasite shape the evolution of virulence
在双亲群体中，从噪声低覆盖度测序数据中快速准确地进行基因型填补	Triay, C.	PDF	N/A	Fast and accurate imputation of genotypes from noisy low-coverage sequencing data in bi-parental populations
蛋白质凝聚物中分子相互作用强度的光学表征	Beck, T.	PDF	N/A	Optical characterization of molecular interaction strength in protein condensates
植物物种间的重复全球适应	Nocchi, G.	PDF	N/A	Repeated global adaptation across plant species
使用MEG测量的人类听觉皮层适应寿命的半球差异	Dar, A. H.	PDF	N/A	Hemispheric difference of adaptation lifetime in human auditory cortex measured with MEG
tRNA基因表达的适应性损失导致海洋蓝藻Synechococcus对噬菌体的抗性	Zborowsky, S.	PDF	N/A	Adaptive loss of tRNA gene expression leads to phage resistance in a marine Synechococcus cyanobacterium
定量蛋白质组学鉴定出在低级别浆液性卵巢癌中保守的蛋白质及粘蛋白-16的调控改变	Tarney, C. M.	PDF	N/A	Quantitative Proteomics Identifies Conserved Proteins and Altered Regulation of Mucin-16 in Low Grade Serous Ovarian Cancers
基于微管重叠区域中的马达蛋白的染色体排列模型	Sigmund, I.	PDF	N/A	Model for chromosome congression based on motor proteins in microtubule overlaps
ATAC与RNA测序的整合揭示了经典和非经典斑马鱼成骨细胞中的染色质和转录组特征，并指出了entpd5a调控的机制	Petratou, K.	PDF	N/A	Integration of ATAC and RNA-sequencing identifies chromatin and transcriptomic signatures in classical and non-classical zebrafish osteoblasts and indicates mechanisms of entpd5a regulation
原癌基因Bcl3的磷酸化诱导的灵活性调节NF-κB p52同源二聚体的转录激活	Pan, W.	PDF	N/A	Phosphorylation-induced flexibility of proto-oncogenic Bcl3 regulates transcriptional activation by NF-κB p52 homodimer
探究配体介导的Pre-miR21构象动力学：基于机器学习的增强采样研究	Aureli, S.	PDF	N/A	Investigating Ligand-Mediated Conformational Dynamics of Pre-miR21: A Machine-Learning-Aided Enhanced Sampling Study
埃及伊蚊VLG-1基因在体内对Vago基因的抗病毒特性提出了挑战	Couderc, E.	PDF	N/A	Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes in vivo
埃及伊蚊VLG-1基因质疑了Vago基因在体内具有抗病毒特性的假设	Couderc, E.	PDF	N/A	Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes in vivo
一种能够穿过血脑屏障的肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了与抗惊厥、神经保护和抗炎特性相关的药理性低体温。	Ferhat, L.	PDF	N/A	A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
纳米孔直接RNA测序的解复用和条形码特异性自适应采样	van der Toorn, W.	PDF	N/A	Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing
用于 ArtiaX 的相机路径、建模和图像处理工具	Ermel, U. H.	PDF	N/A	Camera Paths, Modeling, and Image Processing Tools for ArtiaX
视网膜辨别力对自然场景的适应	Ding, X.	PDF	N/A	Adaptation of retinal discriminability to natural scenes
ReAct项目：分析来自23个不同实验室的数据，以表征在两组活动水平命题下DNA的恢复情况	Gill, P.	PDF	N/A	The ReAct project: Analysis of data from 23 different laboratories to characterise DNA recovery given two sets of activity level propositions
囊杆菌素非靶向分析揭示了其在真核生物中良好的安全性、超氧阴离子还原能力及SCARB1抑制作用	Risch, T.	PDF	N/A	Cystobactamid off-target profiling reveals favorable safety, superoxide reduction, and SCARB1 inhibition in eukaryotes
LIFERING是一种E3泛素连接酶，能够泛素化酰基辅酶A脱氢酶样蛋白IBR3，并在DNA损伤时协调细胞增殖与死亡。	Kallai, B.	PDF	N/A	LIFERING, an E3 ligase ubiquitinates the acyl-CoA dehydrogenase-like protein IBR3, and coordinates cell proliferation and death upon DNA damage
靶向乙酰转移酶NAT10可纠正人类额颞叶痴呆神经元的病理，并延长体内果蝇tau病模型的寿命	Paonessa, F.	PDF	N/A	Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model
针对乙酰转移酶NAT10进行靶向治疗，可以纠正人类额颞叶痴呆神经元的病理变化，并在果蝇体内tau蛋白病变的模型中延长寿命。	Paonessa, F.	PDF	N/A	Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal dementia neurons and extends lifespan in an in vivo Drosophila tauopathy model
多色荧光活细胞成像在盘基网柄菌中的应用	Hashimura, H.	PDF	N/A	Multi-color fluorescence live-cell imaging in Dictyostelium discoideum
线粒体分裂调控皮质中星形胶质细胞的形态发生与组织结构	Salazar, M. P. R.	PDF	N/A	Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
大黄素增强的人脐带间充质干细胞外泌体通过靶向炎症和细胞焦亡缓解急性胰腺炎	Liu, X.	PDF	N/A	Emodin-Enhanced hUC-MSC Extracellular Vesicles Alleviate Acute Pancreatitis by Targeting Inflammation and Pyroptosis
生长中的巨噬细胞通过胞饮作用调节高水平的溶质通量	Tebeje, B. M.	PDF	N/A	Growing Macrophages Regulate High Rates of Solute Flux by Pinocytosis
人类卫星3号DNA编码了百万碱基尺度的转录因子结合平台	Franklin, J. M.	PDF	N/A	Human Satellite 3 DNA encodes megabase-scale transcription factor binding platforms
SpotMAX：一种用于多维自动斑点检测和定量的通用框架	Padovani, F.	PDF	N/A	SpotMAX: a generalist framework for multi-dimensional automatic spot detection and quantification
对西丘两具早期铜石并用时代个体的古DNA分析	Dogu, A.	PDF	N/A	Ancient DNA analyses of two Early Chalcolithic Individuals from the West Mound
年龄依赖性的神经3D染色质互作组的成熟与在丰富环境中的再生	Gancedo-Verdejo, J.	PDF	N/A	Age-Dependent Maturation and Rejuvenation of the Neural 3D Chromatin Interactome in Enriched Environments
胰腺胰岛α细胞通过调节相邻β细胞的微管稳定性来调节胰岛素分泌，并在小鼠和人类胰岛中诱导功能异质性。	Ho, K.-H.	PDF	N/A	Pancreatic islet alpha cells regulate microtubule stability in neighboring beta cells to tune insulin secretion and induce functional heterogeneity in individual mouse and human islets
使用卷积神经网络预测塑料降解酶的框架	Hasnat, S.	PDF	N/A	A Framework for Accurate Prediction of Plastic-Degrading Enzymes using Convolutional Neural Networks
将个人评估和小团体评估结合作为教学策略的好处	Arini, G. S.	PDF	N/A	Benefits of combining individual and small group assessments as an instructional strategy
NHGRI-EBI GWAS目录：可重用性、可持续性和多样性的标准	Cerezo, M.	PDF	N/A	The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity
在大西洋奴隶贸易期间和之后，圣多美岛上的嵌套混血现象	Ciccarella, M.	PDF	N/A	Nested admixture during and after the Trans-Atlantic Slave Trade on the island of Sao Tome
人类转录组中RNA修饰的综合调查	Mulroney, L.	PDF	N/A	A comprehensive survey of RNA modifications in a human transcriptome
通过奇异积分算子模拟昆虫外骨骼中的率无关阻尼	Pons, A.	PDF	N/A	Modelling rate-independent damping in insect exoskeleta via singular integral operators
对T细胞受体进行远程力调制揭示了CD4+ T细胞激活的NFAT阈值	Clarke, J. J.	PDF	N/A	Remote force modulation of the T-cell receptor reveals an NFAT-threshold for CD4+ T cell activation
阿拉斯加产红藻、德瓦拉藻和掌状藻的培养方案	Umanzor, S.	PDF	N/A	Cultivation protocols the rhodophytes, Devaleraea mollis and Palmaria hecatensis from Alaska
BoundaryStats：一个用于计算边界重叠统计的R包	Luo, A. R.	PDF	N/A	BoundaryStats: An R package to calculate boundary overlap statistics
醛固酮分泌腺瘤中的MCOLN3体细胞突变导致原发性醛固酮增多症。	van Rooyen, D.	PDF	N/A	Somatic Mutations in MCOLN3 in Aldosterone-Producing Adenomas cause Primary Aldosteronism.
基于肽的复合凝聚物通过阳离子-π相互作用稳定用于细胞工程	Sun, Y.	PDF	N/A	Peptide-Based Complex Coacervates Stabilized by Cation-π Interactions for Cell Engineering
Toden-E：基于拓扑和密度的集成聚类方法，用于利用PAG网络和LLM在功能基因组学中开发超级PAG	Li, Q.	PDF	N/A	Toden-E: Topology-Based and Density-Based Ensembled Clustering for the Development of Super-PAG in Functional Genomics using PAG Network and LLM
通过转录组学剖析乳腺癌异质性：揭示多样致病因素以发现常见生物标志物	Hossain, M. U.	PDF	N/A	Dissecting Breast Cancer Heterogeneity Through Transcriptomics Insights of Diverse Etiological Factors for Common Biomarker Discovery
TCGA泛癌中位点特异性重复元件的失调	Wang, C.	PDF	N/A	Dysregulation of locus-specific repetitive elements in TCGA pan-cancers
LIV结合蛋白中不同构象及配体逃逸路径的相对稳定性：分子动力学模拟研究	Das, J.	PDF	N/A	Relative stability of different conformations and pathways of ligand escape in LIV-binding protein: A molecular dynamics simulation study
全反式维甲酸介导的ADAR1降解与PD-1阻断协同作用抑制胰腺癌	Li, C.-F.	PDF	N/A	All-trans retinoic acid-mediated ADAR1 degradation synergizes with PD-1 blockade to suppress pancreatic cancer
中间普氏菌的蛋白酶interpain A促进人舌鳞状细胞癌细胞的增殖和迁移	Chang, S.-M.	PDF	N/A	The protease interpain A of Prevotella intermedia promotes human OSCC cells proliferation and migration
二苯乙烯碘化物氯化物通过靶向MYCN诱导的线粒体改变，抑制MYCN扩增的神经母细胞瘤。	Epp, S.	PDF	N/A	Diphenyleneiodonium chloride inhibits MYCN-amplified neuroblastoma by targeting MYCN induced mitochondrial alterations
岩藻多糖-铜纳米颗粒协同增强癌细胞铜死亡与免疫治疗	Chen, H.	PDF	N/A	Fucoidan-Copper Nanoparticles to Potentiate Synergistic Cancer Cell Cuproptosis and Immunotherapy
从单一物种到群落：使用Feliplex进行微卫星扩增子测序以监测猫科动物	Rana, D.	PDF	N/A	From single species to communities: microsatellite amplicon sequencing to monitor felids using Feliplex
稻田鸟类群落组成：收获阶段和周围植被的影响——来自阿格内博德韦帕农场的见解。	Ibrahim, I.	PDF	N/A	Avifauna composition in Rice plantations: effects of Harvesting Stage and Surrounding Vegetation. Insights from Weppa Farm, Agenebode.
Rag2Mol：基于检索增强生成的结构导向药物设计	Zhang, P.-D.	PDF	N/A	Rag2Mol: Structure-based drug design based on Retrieval Augmented Generation
探究亨廷顿蛋白N17结构域的曲率感知能力	Nanajkar, N.	PDF	N/A	Investigating the curvature sensing ability of Huntingtin's N17 domain
通过线粒体移植增强人胶质母细胞瘤中辐射诱导的活性氧生成	Marshall, K.	PDF	N/A	Enhancing Radiation-induced Reactive Oxygen Species Generation Through Mitochondrial Transplantation in Human Glioblastoma
成纤维细胞分泌的lumican和biglycan通过旁分泌调节IFN-γ分泌的CD4+ T细胞，对过敏性接触性皮炎具有保护作用。	Maiti, G.	PDF	N/A	Paracrine regulations of IFN-γ secreting CD4+ T cells by lumican and biglycan are protective in allergic contact dermatitis
核效应在决定密码子使用依赖性的人类基因表达中起着重要作用。	Garg, R.	PDF	N/A	Nuclear effects play an important role in determining codon usage-dependent human gene expression
低秩全矩阵分解用于单细胞RNA-seq中的丢弃填补，并与下游应用的填补算法进行基准测试	Huang, J.	PDF	N/A	Low-Rank Full Matrix Factorization for dropout imputation in single cell RNA-seq and benchmarking with imputation algorithms for downstream applications
突触小泡内吞缺陷是帕金森病和路易体痴呆中与GBA相关的认知功能障碍的基础	Vidyadhara, D. J.	PDF	N/A	Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson's disease and Dementia with Lewy bodies
40 Hz感觉刺激增强阿尔茨海默病小鼠模型中导航时的CA3-CA1协调和前瞻性编码	Paulson, A. L.	PDF	N/A	40 Hz sensory stimulation enhances CA3-CA1 coordination and prospective coding during navigation in a mouse model of Alzheimer's disease
内侧延伸杏仁核Otp谷氨酸能神经元的性类固醇受体表达及性别差异	Gonzalez-Alonso, A.	PDF	N/A	Expression of sex steroid receptors and sex differences of Otp glutamatergic neurons of the medial extended amygdala
触屏响应精度对探索/利用权衡敏感	Mueller, D.	PDF	N/A	Touchscreen response precision is sensitive to the explore/exploit tradeoff
活细菌全细胞生物传感器的成像揭示了哺乳动物肠道炎症区域唾液酸的可利用性空间分布。	Carreno, D.	PDF	N/A	Imaging of live bacterial whole-cell biosensors illuminates spatial sialic acid availability within the inflamed mammalian gut
使用变分自编码器设计极简大肠杆菌基因组	Barnes, C. P.	PDF	N/A	Designing minimal E. coli genomes using variational autoencoders
通过改良的cDICE方法选择巨型单层囊泡（GUVs）的大小	Chen, A.	PDF	N/A	Size Selection of Giant Unilamellar Vesicles (GUVs) via Modified cDICE Method
工作记忆中的干扰预期与跨空间尺度的θ和β振荡相关	Jung, D. Y.	PDF	N/A	Distractor anticipation during working memory is associated with theta and beta oscillations across spatial scales
在面对模糊的感觉输入时，CA3/齿状回表征的排斥是由不同的内部信念驱动的。	Guo, W. A.	PDF	N/A	Repulsion of CA3 / dentate gyrus representations is driven by distinct internal beliefs in the face of ambiguous sensory input
前扣带皮层中一种常见的目标维持机制，适用于信息和努力选择	Gonzalez, V. V.	PDF	N/A	A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices
行走过程中经颅磁刺激对腿部轨迹的调节	Bourgeois, H.	PDF	N/A	Modulation of leg trajectory by transcranial magnetic stimulation during walking
2型糖尿病重塑侧支循环并促进缺血性卒中后白细胞粘附	Sato, Y.	PDF	N/A	Type 2 diabetes remodels collateral circulation and promotes leukocyte adhesion following ischemic stroke
SC10X/U：一种用于非侵入性记录颈脊髓神经活动的高密度电极系统	Mehra, P.	PDF	N/A	SC10X/U: A High-density Electrode System for Non-Invasive Recording of Neural Activity of the Cervical Spinal Cord
十二种磷酸模拟突变促使重组全长人类tau蛋白形成成对螺旋丝	Lövestam, S.	PDF	N/A	Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments
在空间导航过程中对决策神经动力学的全皮层表征	Haley, S. P.	PDF	N/A	Cortex-wide characterization of decision-making neural dynamics during spatial navigation
钠泄漏通道NALCN缺失对纹状体Drd2棘突投射神经元具有性别偏向效应	Castell, L.	PDF	N/A	Sex-biased effect of sodium leak channel NALCN deletion in striatal Drd2 spiny projection neurons
在帕金森病rAAV6-α-Syn+PFFs诱导的大鼠模型中，全身给予可溶性TNF抑制剂XPro1595后缺乏神经保护作用	Fredlund, F.	PDF	N/A	Lack of neuroprotection after systemic administration of the soluble TNF inhibitor XPro1595 in an rAAV6-α-Syn+PFFs-induced rat model for Parkinson's disease
RPE特异性MCT2表达促进视网膜色素变性模型中的锥体细胞存活	Chandler, L. C.	PDF	N/A	RPE-specific MCT2 expression promotes cone survival in models of retinitis pigmentosa
YTHDF蛋白塑造了阿尔茨海默病的大脑基因特征	Tasaki, S.	PDF	N/A	The YTHDF Proteins Shape the Brain Gene Signatures of Alzheimer's Disease
Omega-3脂肪酸通过海马体中miRNAs的调控，使突触后密度蛋白恢复正常，并防止DEHP引起的学习记忆功能障碍。	Ding, M.	PDF	N/A	Omega-3 fatty acid normalizes postsynaptic density proteins via miRNAs regulation in hippocampus and prevents DEHP-induced impairment of learning and memory in mice
通过ds-Tango揭示的果蝇求偶过程中趋同的嗅觉回路	Fisher, J. D.	PDF	N/A	Convergent olfactory circuits for courtship in Drosophila revealed by ds-Tango
海马区尖波涟漪与新皮层慢振荡之间潜在的双向交互作用的地形图	Swanson, R. A.	PDF	N/A	Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations
在大鼠内侧内嗅皮层中，癫痫持续状态后对CBD的GABA-A受体反应	Henley, B. S.	PDF	N/A	A GABA-A receptor response to CBD following status epilepticus in the medial entorhinal cortex of the rat
效应器选择先于运动指定：来自运动计划中重复效应的证据	Seegelke, C.	PDF	N/A	Effector selection precedes movement specification: evidence from repetition effects in motor planning
过量补充叶酸会降低雄性和雌性黑腹果蝇在缺氧24小时后的存活率。	Gunnala, S.	PDF	N/A	Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster
多巴胺能、胆碱能和去甲肾上腺素能网络在帕金森病嗅觉减退中的作用	Perot, J.-B.	PDF	N/A	The role of dopaminergic, cholinergic and noradrenergic networks in hyposmia in Parkinson's disease
ALS相关的RNA结合蛋白通过调节REST来汇聚于UNC13A的转录	Watanabe, Y.	PDF	N/A	ALS-associated RNA binding proteins converge on UNC13A transcription through regulation of REST
独特的运动控制和学习优化：自定节奏的运动学习实现了与过度训练不同的运动模式。	Hayashi, T.	PDF	N/A	Distinct optimization of motor control and learning: Self-paced motor learning achieves different motor patterns from overtrained
解码人类大脑皮层和杏仁核中与心理创伤相关的转录组特征	Hicks, E. M.	PDF	N/A	Decoding the transcriptomic signatures of psychological trauma in human cortex and amygdala
预防性使用米诺环素可减轻外周神经病变大鼠模型的痛觉过敏和抑郁样行为：一项初步研究	Le, A. C. T.	PDF	N/A	Preemptive minocycline decreases allodynia and depressive-like behaviors in a peripheral neuropathy rat model: a preliminary study
单侧空间忽略中神经振荡相位同步的频率特异性半球偏侧化	Okazaki, Y. O.	PDF	N/A	Frequency-specific hemispheric bias in phase entrainment of neural oscillations in unilateral spatial neglect
SARS-CoV-2 KP.3.1.1和XEC通过NTD糖基化增强的免疫逃逸能力	Liu, J.	PDF	N/A	Enhanced immune evasion of SARS-CoV-2 KP.3.1.1 and XEC through NTD glycosylation
近期地方性冠状病毒感染与更高水平的SARS-CoV-2交叉反应性Fc受体结合抗体相关	Bean, D. J.	PDF	N/A	Recent Endemic Coronavirus Infection Associates With Higher SARS-CoV-2 Cross-Reactive Fc Receptor Binding Antibodies
重新激活的I型干扰素信号传导与COVID-19的年龄依赖性差异有关	Petrov, L.	PDF	N/A	Rewired type I IFN signaling is linked to age-dependent differences in COVID-19
通过利用互补防御系统增强嗜热链球菌的噬菌体抗性	Leprince, A.	PDF	N/A	Strengthening Phage Resistance of Streptococcus thermophilus by Leveraging Complementary Defense Systems
免疫史对高致病性H5N1亚型2.3.4.4b病毒挑战的疾病严重程度有修饰作用	Brigleb, P. H.	PDF	N/A	Immune History Modifies Disease Severity to HPAI H5N1 Clade 2.3.4.4b Viral Challenge
人巨细胞病毒（HCMV）的有效感染多重性取决于细胞20S蛋白酶体的活性。	Cataldo, K. M.	PDF	N/A	The effective multiplicity of infection for HCMV depends on activity of the cellular 20S proteasome
CABO-16S：一种综合了古菌、细菌、细胞器16S的数据库，用于环境样本中真核生物和原核生物扩增子分析	Eitel, E. M.	PDF	N/A	CABO-16S : A Combined Archaea, Bacteria, Organelle 16S database for amplicon analysis of prokaryotes and eukaryotes in environmental samples
蒲桃（Syzygium cumini (L.) Skeels）具有耐热且选择性抗炭疽杆菌活性	Kaur, R.	PDF	N/A	Syzygium cumini (L.) Skeels has Thermostable and Selective Anti-Bacillus anthracis Activity
比较分析Pseudoalteromonas tunicata生物膜发育的蛋白质组学揭示了一类独特的依赖Ca2+的粘附素	Ali, S.	PDF	N/A	Comparative proteomics of biofilm development in Pseudoalteromonas tunicata discovers a distinct family of Ca2+-dependent adhesins
农业系统中的土壤性质影响微生物基因组特征	Goodall, T. I.	PDF	N/A	Soil properties in agricultural systems affect microbial genomic traits
短杆菌肽S对不同培养复杂度下微生物生理的影响	Shlakhter, O.	PDF	N/A	The impact of tropodithietic acid on microbial physiology under varying culture complexities
先前存在的H1N1免疫力可减少牛H5N1流感病毒引起的严重疾病	Le Sage, V.	PDF	N/A	Pre-existing H1N1 immunity reduces severe disease with bovine H5N1 influenza virus
野生鸟类自然种群中与血孢子虫相关的嵌套RNA病毒的流行与多样性	Esperanza, C. W.	PDF	N/A	Prevalence and Diversity of Haemosporidian-Associated Matryoshka RNA Viruses in a Natural Population of Wild Birds
无细胞重组酶集成布尔输出系统（CRIBOS）	Chen, J.	PDF	N/A	Cell-Free Recombinase Integrated Boolean Output System (CRIBOS)
通过下边缘区神经元周围网降解增强恐惧消退：青少年酒精暴露的调节作用	Obray, J. D.	PDF	N/A	Enhanced Fear Extinction Through Infralimbic Perineuronal Net Digestion: The Modulatory Role of Adolescent Alcohol Exposure
内源性神经元DNA双链断裂并不足以驱动大脑老化和神经退行性变。	Cohen, S.	PDF	N/A	Endogenous neuronal DNA double-strand breaks are not sufficient to drive brain aging and neurodegeneration
迷幻、睡眠和镇静状态的神经相关性支持意识的全局理论	Dai, R.	PDF	N/A	Neural Correlates of Psychedelic, Sleep, and Sedated States Support Global Theories of Consciousness
利用MEG研究自闭症与非自闭症青少年视角采择的神经振荡基础	Seymour, R. A.	PDF	N/A	The Neural Oscillatory Basis of Perspective-Taking in Autistic and Non-Autistic Adolescents using MEG
念珠菌属杀鱼菌感染中的异铁载体转运基因表达及类群特异性菌丝形成	Gifford, H.	PDF	N/A	Xenosiderophore transporter gene expression and clade-specific filamentation in Candida auris killifish infection
高频并行进化的致病性鲍曼不动杆菌培养物证据	Mclaughlin, J.	PDF	N/A	Evidence for high-frequency parallel evolution in virulent A. baumannii cultures
铜绿假单胞菌的烷基喹诺酮应答被粪肠球菌所抑制	Fink, M. M.	PDF	N/A	Pseudomonas aeruginosa Alkyl Quinolone Response is dampened by Enterococcus faecalis
多代蛋白水解失活限制在微妙基因组低甲基化后	Shmidov, E.	PDF	N/A	Multigenerational Proteolytic Inactivation of Restriction Upon Subtle Genomic Hypomethylation
自发α波段侧化通过调节皮层兴奋性延长视觉信息在表象记忆中的持续时间。	Smith, P. J. C.	PDF	N/A	Spontaneous alpha-band lateralization extends persistence of visual information in iconic memory by modulating cortical excitability.
# BioRxiv 2024-10-22 Papers

标题	作者	PDF链接	代码仓库	Title
棒状细菌荧光假单胞菌SBW25的球形mreB缺失突变体的进化救援	Yulo, P. R.	PDF	N/A	Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25
在微型鱼类丹尼奥内拉·大脑中，催产素介导的社会偏好与社会强化奖励学习	Penalva, A.	PDF	N/A	Oxytocin-mediated social preference and socially reinforced reward learning in the miniature fish Danionella cerebrum
循环连接通过解释消除机制促进遮挡物体的识别。	Kang, B.	PDF	N/A	Recurrent connections facilitate occluded object recognition by explaining-away
果蝇母体和早期合子转录调控的演变	Omura, C.	PDF	N/A	Evolution of maternal and early zygotic transcript regulation across Drosophila
T细胞牵引力表现出依赖于刺激和细胞亚型的时序模式。	Mustapha, F.	PDF	N/A	T Cell Traction Forces show temporal patterns which Depend on Stimulation and Cell Subtype
在注意力瞬盲期间评估工作记忆表征：一种比较建模方法	Wang, S.	PDF	N/A	Evaluating Working Memory Representations during the Attentional Blink: A Comparative Modeling Approach
HuR通过促进多嘧啶序列结合蛋白的结合，增强SARS-CoV-2非结构蛋白在基因组5'-UTR区域的翻译。	Raheja, H.	PDF	N/A	HuR enhances SARS-CoV-2 non-structural protein translation through the genomic 5'-UTR, by promoting polypyrimidine tract-binding protein binding
PPE25（Rv1787）-PE18（Rv1788）-PPE26（Rv1789）基因簇参与了结核分枝杆菌的免疫逃避。	Mukku, R. P.	PDF	N/A	The PPE25 (Rv1787)-PE18 (Rv1788)-PPE26 (Rv1789) gene cluster is involved in immune evasion by Mycobacterium tuberculosis
自我评估的贝叶斯更新解释了社会支配和胜者-败者效应	Perkes, A.	PDF	N/A	Bayesian updating for self-assessment explains social dominance and winner-loser effects
统一稀疏编码、预测编码和除法归一化	Lian, Y.	PDF	N/A	Unifying sparse coding, predictive coding, and divisive normalization
由致病性减弱肺炎链球菌生物合成基因突变体引发的微侵袭及免疫反应	Weight, C. M.	PDF	N/A	Microinvasion and immunity elicited by disease-attenuated pneumococcal biosynthesis gene mutants
有性生殖种群中有益、有害和中性突变对适应性影响的整合模型	Irlam, G.	PDF	N/A	An integrated model of the effects on fitness of beneficial, deleterious, and neutral mutations in sexual populations
雄性豆娘的Opsin基因表达可塑性和光谱敏感性可能介导了对雌性颜色形态的检测。	Roberts, N. S.	PDF	N/A	Opsin gene expression plasticity and spectral sensitivity in male damselflies could mediate female colour morph detection
翻译：光合作用对翻译机制的需求促使植物细胞器中保留了冗余的tRNA代谢	DeTar, R. A.	PDF	N/A	Photosynthetic demands on translational machinery drive retention of redundant tRNA metabolism in plant organelles
高粱1（Sorghum bicolor）气生根分泌的粘液可作为固氮菌的宿主，这些固氮菌能为植物提供大量氮素。	Venado, R. E.	PDF	N/A	Mucilage Produced by Sorghum 1 (Sorghum bicolor) Aerial Roots Hosts Diazotrophs that Provide Significant Amounts of Nitrogen to the Plant
鉴定用于改进狂犬病病毒监测的支系特异性单核苷酸多态性	Kumar, A.	PDF	N/A	Identification of clade-defining single nucleotide polymorphisms for improved rabies virus surveillance
多模态子空间独立向量分析有效地捕捉了大脑结构与功能之间的潜在关系。	Li, X.	PDF	N/A	Multimodal subspace independent vector analysis effectively captures the latent relationships between brain structure and function
在感染早期，一个具有转录活性的脂质囊泡包裹着注入的Chimalliviridae病毒基因组。	Armbruster, E.	PDF	N/A	A transcriptionally active lipid vesicle encloses theinjected Chimalliviridae genome in early infection
人类大脑中电刺激的基因表达特征	Chatterjee, S.	PDF	N/A	The gene expression signature of electrical stimulation in the human brain
通过HCN通道对NMDA放大进行输入特异性调控在鼠L2/3层锥体神经元中的作用	Olah, V. J.	PDF	N/A	Input-specific gating of NMDA amplification via HCN channels in mouse L2/3 pyramidal neurons
活动依赖性的突触聚集在发育中的视网膜下丘脑系统中导致了眼特异性竞争的形成。	Zhang, C.	PDF	N/A	Activity-dependent synapse clustering underlies eye-specific competition in the developing retinogeniculate system
短期社交隔离通过作用于下丘脑神经元，以性别和情境依赖的方式促进社交行为。	Zhao, X.	PDF	N/A	Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner
OCA-B促进干细胞样CD4+ T细胞的致病性成熟1和自身免疫性脱髓鞘	Hughes, E. P.	PDF	N/A	OCA-B promotes pathogenic maturation 1 of stem-like CD4+ T cells and autoimmune demyelination
大豆品种北京成功结瘤所需的Sinorhizobium fredii USDA257的功能性VI型分泌系统	Reyes-Perez, P.	PDF	N/A	The functional type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful nodulation with Glycine max cv Pekin
基准测试单个降解蛋白质的鉴定，以探索古代蛋白质的最佳搜索策略	Rodriguez Palomo, I.	PDF	N/A	Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins
CAT Bridge：一种从多组学数据中高效挖掘基因-代谢物关联的工具包	Yang, B.	PDF	N/A	CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics data
斑马鱼活体成像显示，在早期发育过程中，只有大约2%而非50%的运动神经元通过凋亡死亡。	Jia, H.	PDF	N/A	Zebrafish live imaging reveals only around 2% rather than 50% of motor neurons die through apoptosis during early development
系统性炎症加速了在过度表达人α-突触核蛋白的帕金森病大鼠模型中的神经退行性变	Massaro Cenere, M.	PDF	N/A	Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein
通过单细胞RNA测序揭示肺腺癌中化疗诱导的免疫景观重塑与代谢重编程	Huang, Y.	PDF	N/A	Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing
心理压力通过miR-335-3p/Fos信号通路扰乱破骨细胞的骨代谢。	Zhang, J.	PDF	N/A	Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast
化学诱导的衰老促使人类类小胶质细胞发生功能性变化	Armanville, S.	PDF	N/A	Chemically induced senescence prompts functional changes in human microglia-like cells
聚类内分析揭示了组织特异性的突变模式	Choudalakis, S.	PDF	N/A	Intra-clustering analysis reveals tissue-specific mutational patterns
噬菌体抗性与土壤细菌贪噬菌属（Variovorax sp.）的密度增加相关，并导致群落结构的改变。	Castledine, M.	PDF	N/A	Phage resistance is associated with density increases in the soil bacterium Variovorax sp. and results in changes to community structure
通过CoVerage进行的计算机基因组监测预测并描述了SARS-CoV-2的关注变种	Norwood, K.	PDF	N/A	In silico genomic surveillance by CoVerage predicts and characterizes SARS-CoV-2 Variants of Interest
利用自然生理状况标记揭示自然啮齿动物种群中轻度干旱条件的负面影响	Keilani, H. S.	PDF	N/A	Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura
社会老龄化可以保护群居灵长类动物免受传染病的影响。	Siracusa, E. R.	PDF	N/A	Social ageing can protect against infectious disease in a group-living primate
利用7T MRI研究人脑皮层下区域的工作记忆更新过程	Trutti, A. C.	PDF	N/A	Investigating working memory updating processes of the human subcortex using 7T MRI
srahunter：一个用户友好的工具，用于加速和简化从NCBI SRA下载数据	Bortoletto, E.	PDF	N/A	srahunter: a user-friendly tool to speed up and simplify data downloading from NCBI SRA
细菌裂解噬菌体生命周期的单细胞成像	Wedd, C.	PDF	N/A	Single-cell imaging of the lytic phage life cycle in bacteria
通过亲代微生物组对后代行为、海马体内的DNA甲基化和基因表达进行胎儿编程	Gustafson, K. L.	PDF	N/A	Fetal programming by the parental microbiome of offspring behavior, and DNA methylation and gene expression within the hippocampus
湖泊螺旋藻（蓝藻）的化学指纹揭示了局部分子适应性	Roussel, T.	PDF	N/A	Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation
无细胞实验揭示，HIV-1衣壳能够保护逆转录产物免受cGAS的影响。	Scott, T. M.	PDF	N/A	Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS
增殖与分化之间的失衡是微小RNA缺陷型成松果体瘤发展的基础	Fraire, C. R.	PDF	N/A	An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma
社会地位对非洲慈鲷后续求偶和交配活动的影响	Martashvili, A.	PDF	N/A	Effects of social position on subsequent courtship and mating activity in an African cichlid
豌豆蚜的母体vGluT2与胚胎mGluR3信号传递系统控制着后代翅膀二型性	Yuan, Y.	PDF	N/A	The maternal vGluT2 and embryonic mGluR3 signaling relay system controls offspring wing dimorphism in pea aphid
通过基于典型相关特征的广义最大熵进行细粒度细胞反卷积	Kamm, J.	PDF	N/A	Fine-scale cellular deconvolution via generalized maximum entropy on canonical correlation features
先天性心脏缺陷在左侧与右侧鸟类心脏神经嵴消融后表现出差异。	Solovieva, T.	PDF	N/A	Congenital heart defects differ following left versus right avian cardiac neural crest ablation
在高分辨率和准确性下，对听觉中脑的神经编码进行建模	Drakopoulos, F.	PDF	N/A	Modeling neural coding in the auditory midbrain with high resolution and accuracy
通过调节RAS蛋白的棕榈酰化来控制其信号传导	Zhu, J.	PDF	N/A	Control of the signaling of RAS proteins by modulating their palmitoylation
通过分离的大脑杏仁核回路控制先天嗅觉效价	Howe, J. R.	PDF	N/A	Control of innate olfactory valence by segregated cortical amygdala circuits
断裂诱导复制被激活，以修复SETX缺陷细胞中与R-环相关的双链断裂	Wu, T.	PDF	N/A	Break-induced replication is activated to repair R-loop-associated double-strand breaks in SETX-deficient cells
基因调控网络结构揭示了扰动效应的分布情况	Aguirre, M.	PDF	N/A	Gene regulatory network structure informs the distribution of perturbation effects
禁用链接的概率视角：它们在植物-蜂鸟群落中的普遍性及其对群落稳健性的影响	Duchenne, F.	PDF	N/A	A probabilistic view of forbidden links: their prevalence and their consequences for the robustness of plant-hummingbird communities
中央杏仁核中的效价和显著性编码	Kong, M.-S.	PDF	N/A	Valence and Salience Encoding in the Central Amygdala
强化学习指导单细胞测序解码谱系和细胞命运决定	Fu, Z.	PDF	N/A	Reinforcement learning guides single-cell sequencing in decoding lineage and cell fate decisions
生态竞争群落中的稳健共存	Lechon-Alonso, P.	PDF	N/A	Robust coexistence in ecological competitive communities
跨界鱼类：评估跨界鱼类种群的过度捕捞脆弱性	Gangal, M.	PDF	N/A	Unbounding fish: Assessing vulnerability to overexploitation for transboundary fish populations
选择强度在何时会增加进化拯救的概率？	Xu, K.	PDF	N/A	When does the probability of evolutionary rescueincrease with the strength of selection?
通过极端瓶颈清除高度有害等位基因	Stuart, O. P.	PDF	N/A	Purging of highly deleterious alleles through an extreme bottleneck
MinD蛋白调控Haloferax volcanii中CetZ1的定位	Brown, H. J.	PDF	N/A	MinD proteins regulate CetZ1 localisation in Haloferax volcanii
基于结构的RyR通道操作机制：钙离子和镁离子的作用	Zahradnikova, A.	PDF	N/A	Structure-based mechanism of RyR channel operation by calcium and magnesium ions
基于新型扩增子的近全长基因组（NFLG）测序方法用于HIV-1 M组重组形式的研究	Moscona, R.	PDF	N/A	Novel Amplicons based Method for Near-Full-Length Genome (NFLG) Sequencing of HIV-1 Group M Recombinant Forms
用于分子研究的新型复制能力报告表达裂谷热病毒	Nogales, A.	PDF	N/A	Novel replication-competent reporter-expressing Rift Valley fever viruses for molecular studies
贝叶斯估计产生了反韦伯变异性	Prat-Carrabin, A.	PDF	N/A	Bayesian estimation yields anti-Weber variability
大肠杆菌的系统发育通过blaTEM-1的可变表达驱动了阿莫西林-克拉维酸的耐药性。	Matlock, W.	PDF	N/A	E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1
通用高通量图像定量分析细胞内亚细胞结构动态及空间分布	Grinstaff, M.	PDF	N/A	Universal high-throughput image quantification of subcellular structure dynamics and spatial distributions within cells
源自患者的结肠上皮类器官揭示了儿童溃疡性结肠炎中与脂质相关的代谢功能障碍	Ojo, B. A.	PDF	N/A	Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis
肠道微生物群介导的脂质积累作为果蝇对蓝光毒性进化适应的驱动因素	Takada, Y.	PDF	N/A	Gut microbiota-mediated lipid accumulation as a driver of evolutionary adaptation to blue light toxicity in Drosophila
按需定制的主客体结合自由能：一种自动化的OneOPES协议	Febrer Martinez, P.	PDF	N/A	Host-Guest binding free energies a la carte: an automated OneOPES protocol
耳声发射而非行为测量可预测鸟类鸣叫专家的耳蜗神经频率调谐	Karosas, D. M.	PDF	N/A	Otoacoustic emissions but not behavioral measurements predict cochlear-nerve frequency tuning in an avian vocal-communication specialist
北极迁徙草食动物的活动和皮质酮的昼夜和季节性节律：多方面的研究方法	de Jong, M. E.	PDF	N/A	Diel and seasonal rhythmicity in activity and corticosterone in an Arctic migratory herbivore: A multifaceted approach
CNValidatron，利用计算机视觉实现CNV调用的自动化验证	Montalbano, S.	PDF	N/A	CNValidatron, automated validation of CNV calls using computer vision
利用相关性和机制性物种分布模型预测当前和未来环境及气候变化下的虫媒疾病风险：以英国西尼罗河病毒为例的研究。	Withers, A. J.	PDF	N/A	Using correlative and mechanistic species distribution models to predict vector-borne disease risk for the current and future environmental and climatic change: a case study of West Nile Virus in the UK.
表面介导的噬菌体防御对细菌间拮抗作用产生了适应性权衡	Tsai, C.-E.	PDF	N/A	Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism
缺氧应激通过表观基因组和转录程序失调影响胶质瘤相关髓系细胞的功能。	Dzwigonska, M.	PDF	N/A	Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs
定时喂食改善了脆性X综合征小鼠模型的行为结果并减少了炎症。	Wang, H.-B.	PDF	N/A	Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome.
外周阿片受体拮抗作用可缓解芬太尼引起的心血管呼吸抑制，且无厌恶效应。	Ruyle, B.	PDF	N/A	Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects
miR-92a的靶标RBFOX2的过早上调劫持了PTBP剪接，并损害了皮层神经元的分化。	Weissbach, S.	PDF	N/A	Premature upregulation of miR-92a's target RBFOX2 hijacks PTBP splicing and impairs cortical neuronal differentiation.
一份大规模的社区科学数据集揭示了北美红花植物中开花期延迟表型的趋同进化	McKenzie, P. F.	PDF	N/A	A massive community-science dataset reveals convergent evolution of delayed flowering phenology in North American red-flowering plants
AAV血清型转导嗅觉感觉神经元的比较分析	Belfort, B. D.	PDF	N/A	Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons
肌动肌球蛋白收缩力是人多能干细胞诱导中胚层形成的有力抑制因素	Fort, L.	PDF	N/A	Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells
温度诱导的膜转运驱动抗体向大脑的递送	Du, F.	PDF	N/A	Temperature-induced membrane trafficking drives antibody delivery to the brain
化学定义的脂质饮食揭示了基因组最小细胞中脂质组重塑的多功能性	Safronova, N.	PDF	N/A	Chemically defined lipid diets reveal the versatility of lipidome remodeling in genomically minimal cells
DNA/多核糖体相分离与细胞宽度限制共同作用，将核区分离与大肠杆菌的细胞生长耦合起来。	Papagiannakis, A.	PDF	N/A	DNA/polysome phase separation and cell width confinement couple nucleoid segregation to cell growth in Escherichia coli
多巴胺和皮质iPSC衍生的神经元在不同的帕金森病突变中显示出溶酶体和线粒体功能障碍的差异：这对蛋白质沉积与选择性细胞丢失的启示	Chedid, J.	PDF	N/A	Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
皮层阿尔法节律从自然场景背景中插值遮挡的运动	Yeh, L.-C.	PDF	N/A	Cortical alpha rhythms interpolate occluded motion from natural scene context
ReAct项目：分析来自23个不同实验室的数据，以描述在两组活动水平命题下的DNA恢复特征。	Gill, P.	PDF	N/A	The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions
人脑视觉皮层中的行波：基于模型的MEG-EEG方法	Grabot, L.	PDF	N/A	Traveling Waves in the Human Visual Cortex: an MEG-EEG Model-Based Approach
登革病毒复制型双链RNA通过RIG-I和MDA5的协同作用被识别，从而激活先天免疫反应。	Ye, S.	PDF	N/A	Dengue virus replicative-form dsRNA is recognized by RIG-I and MDA5 cooperatively to activate innate immunity
新型抗体可检测原生生物病原体、细胞黏菌和植物中的核质O-岩藻糖	Tiwari, M.	PDF	N/A	Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants
参数依赖性在可识别性中的应用：应用于Tauopathy网络建模参数化的FP-Fisher-KPP反应扩散方程	Rahimabadi, A.	PDF	N/A	Parameter Dependence in Identifiability Applied to FP-Fisher-KPP Reaction-Diffusion Equations Parameterized for Tauopathy Network Modeling
部分相关性作为绘制人脑连接中功能-结构对应关系的工具	Santucci, F.	PDF	N/A	Partial Correlation as a Tool for Mapping Functional-Structural Correspondence in Human Brain Connectivity
依赖于DNA的蛋白激酶抑制剂PI-103和Samotolisib增强CRISPR/Cas9在人类T细胞中的敲入效率	Dzafo, E.	PDF	N/A	DNA-Dependent Protein Kinase Inhibitors PI-103 and Samotolisib Augment CRISPR/Cas9 Knockin Efficiency in Human T Cells
肺炎链球菌的周质和细胞壁中的磷壁酸	Mai, N.	PDF	N/A	Teichoic acids in the periplasm and cell envelope of Streptococcus pneumoniae
放弃四极杆用于质谱碎裂分析：通过高分辨率离子迁移前体隔离实现1,000 Hz速度与100%离子利用率	DeBord, D.	PDF	N/A	Abandoning the Quadrupole for Mass Spectrometry Fragmentation Analysis: Towards 1,000 Hz Speeds with 100% Ion Utilization Using High Resolution Ion Mobility Precursor Isolation
甘蔗黄叶病毒损害了甘蔗对新蚜虫媒介Melanaphis sorghi的转录组防御反应	Pimenta, R. J. G.	PDF	N/A	Sugarcane yellow leaf virus impairs the transcriptomic defense responses of sugarcane to its new aphid vector Melanaphis sorghi
通过冷冻电镜断层成像技术可视化的AMPA受体支架复合物的原位结构与形貌	Held, R. G.	PDF	N/A	In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET
生物科学博士在性别和种族/民族方面的出版差异显著模式	Leap, K.	PDF	N/A	Distinct patterns of bioscience doctoral publication disparities by gender and race/ethnicity
大规模无意盲视实验揭示的身体检测反转效应	Gandolfo, M.	PDF	N/A	A body detection inversion effect revealed by a large-scale inattentional blindness experiment
DprA招募ComM，以促进革兰氏阴性菌在自然转化过程中进行重组	Dalia, T. N.	PDF	N/A	DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria
猕猴V1和V2区中自然纹理的表征几何	Pavuluri, A.	PDF	N/A	The representational geometry for naturalistic textures in macaque V1 and V2
冬季围栏对欧洲芦苇鹿能量消耗和运动活动的影响	Silovsky, V.	PDF	N/A	Impact of winter enclosures on energy expenditure and movement activity of european reed deer
H2O2 重新利用植物的氧气感应机制来控制对氧化应激的转录反应。	Akter, S.	PDF	N/A	H2O2 repurposes the plant oxygen-sensing machinery to control the transcriptional response to oxidative stress
苯并噁嗪介导的微生物群反馈增强了拟南芥的生长和防御能力。	Stengele, K.	PDF	N/A	Benzoxazinoid-mediated microbiome feedbacks enhance Arabidopsis growth and defense
研究大麦的甲基组、其变异及其与基因组、转录组和表型变异的关联	Kühl, M. A.	PDF	N/A	Investigating the barley methylome, its variation and association with genomic, transcriptomic, and phenotypic variation
NUDIX水解酶特异性靶向肌醇焦磷酸，调控磷和铁稳态，并在拟南芥中调控防御基因的表达。	Schneider, R.	PDF	N/A	NUDIX Hydrolases Target Specific Inositol Pyrophosphates and Regulate Phosphate and Iron Homeostasis, and the Expression of Defense Genes in Arabidopsis
一个基因组到蛋白质组的图谱绘制了控制蛋白质组多样性的自然变异，并预测了它们的适应性效应。	Jakobson, C. M.	PDF	N/A	A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects
评估从激酶-底物相互作用和磷酸蛋白质组学数据推断信号通路	Garrido-Rodriguez, M.	PDF	N/A	Evaluating signaling pathway inference from kinase-substrate interactions and phosphoproteomics data
含GluN2B的NMDA受体在突触中的积累介导了BDNF-TrkB信号对突触可塑性和癫痫发生的影响。	De Luca, P.	PDF	N/A	Synaptic accumulation of GluN2B-containing NMDA receptors mediates the effects of BDNF-TrkB signalling on synaptic plasticity and in epileptogenesis
奥杜瓦伊域表达下调线粒体途径：对人类大脑进化和幼态持续的意义	Keeney, J. G.	PDF	N/A	Olduvai domain expression downregulates mitochondrial pathways: implications for human brain evolution and neoteny
转录组图谱识别出两种未被识别的室管膜瘤亚型及髓母细胞瘤中的新通路	Arora, S.	PDF	N/A	Transcriptomic landscape identifies two unrecognized ependymoma subtypes and novel pathways in medulloblastoma
涉及长链非编码RNA MB3及驱动基因MYC和OTX2的电路通过调节HMGN5介导的TGF-β通路，抑制了3组髓母细胞瘤中的细胞凋亡。	Grandioso, A.	PDF	N/A	A circuit involving the lncRNA MB3 and the driver genes MYC and OTX2 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5
SIM和CCS52A1控制根毛细胞的内复制和扩展	Li, L.	PDF	N/A	SIM and CCS52A1 control root hair cell endoreplication and expansion
奥哈卡玉米（Zea mays）地方品种的气生根形成在成年阶段仍然持续，并且受土壤氮和环境湿度的影响较小。	Wilker, J.	PDF	N/A	Aerial root formation in Oaxacan maize (Zea mays) landraces persists into the adult phase and is minimally affected by soil nitrogen and ambient humidity.
COmapper：通过拟南芥长读长测序实现高分辨率减数分裂交叉图谱绘制	Byun, D.	PDF	N/A	COmapper: High-resolution mapping of meiotic crossovers by long-read sequencing in Arabidopsis
利用生物弹射技术、多重CRISPR/Cas9编辑和Indel选择性PCR高效诱变玉米自交系	Rai, M. N.	PDF	N/A	Efficient mutagenesis of maize inbreds using biolistics, multiplex CRISPR/Cas9 editing, and Indel-Selective PCR
外生菌根共生在蔷薇类植物谱系中独立进化，并通过趋同基因重复实现。	van Beveren, F.	PDF	N/A	Ectomycorrhizal symbiosis evolved independently and by convergent gene duplication in rosid lineages
尖峰皮层及相连网络中的结构妥协	Sahlas, E.	PDF	N/A	Structural compromise in spiking cortex and connected networks
根据重要性和难度对人类决策进行优先排序	Aboalasaad, F.	PDF	N/A	Prioritization of decisions by importance and difficulty in human planning
使用MRIQC对未处理的人脑解剖、功能和扩散磁共振成像进行质量评估和控制	Hagen, M. P.	PDF	N/A	Quality assessment and control of unprocessed anatomical, functional, and diffusion MRI of the human brain using MRIQC
视网膜神经节细胞的不同富集构成了所提出的核心神经退行性转录程序的基础	Watkins, T. A.	PDF	N/A	Differential enrichment of retinal ganglion cells underlies proposed core neurodegenerative transcription programs
一个包含2,362份来自三大洲八所兽医教学医院的马粪微生物组的新数据集揭示了地理、品种和疾病的主导影响。	McAdams, Z. L.	PDF	N/A	A novel dataset of 2,362 equine fecal microbiomes from eight veterinary teaching hospital on three continents reveals dominant effects of geography, breed, and disease
新生RNA标记化合物5-乙炔基尿苷（EU）在海葵Nematostella vectensis的DNA中整合。	Kjosavik, M. A.	PDF	N/A	The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in the sea anemone Nematostella vectensis
预测肽结合特异性中单个残基效应的计算方法的互补评估	Ayyildiz, M.	PDF	N/A	Complementary evaluation of computational methods for predicting single residue effects on peptide binding specificities
仔细审查脂质利用会破坏两性霉素B在利什曼原虫杜氏临床分离株中的反应性	Pradhan, S.	PDF	N/A	Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani
根瘤菌属豆科植物天然种群中质粒传递动力学与伙伴质量的进化	Vereau Gorbitz, D.	PDF	N/A	Plasmid transmission dynamics and evolution of partner quality in a natural population of Rhizobium leguminosarum
一种实用且安全的氮芥对角膜损伤的模型	Sandoval-Castellanos, A. M.	PDF	N/A	A Practical and Safe Model of Nitrogen Mustard Injury in Cornea
通过使用轴向电极，提升光纤神经接口在光遗传学和电生理学中的去简并性	Sui, K.	PDF	N/A	Lifting the degeneracy of optical fiber neural interfaces for optogenetics and electrophysiology by using axialtrodes
视网膜色素变性突变型光感受器神经元中ER聚集导致突触蛋白失衡	Thompson, S.	PDF	N/A	ER Aggregation Causes Synaptic Protein Imbalance in Retinitis Pigmentosa Mutant Photoreceptor Neurons
在酵母中重现小鼠基因进化军备竞赛揭示了SLXL1/SLX与SLY1/2竞争结合Spindlins。	Arlt, M. F.	PDF	N/A	Reenacting a mouse genetic evolutionary arms race in yeast reveals SLXL1/SLX compete with SLY1/2 for binding to Spindlins.
在人类世，遗传多样性的丧失将在栖息地破坏结束后仍持续很长时间。	Mualim, K. S.	PDF	N/A	Genetic diversity loss in the Anthropocene will continue long after habitat destruction ends
一种快速、简便且经济的分离核糖体和翻译机器用于结构和功能研究的方法	Erath, J.	PDF	N/A	A rapid, facile, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies
空间转录组学分析揭示了晚期卵巢透明细胞癌的肿瘤内异质性：上皮-间质梯度的存在	Truong Le, T.	PDF	N/A	Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient
高级卵巢透明细胞癌的空间转录组分析揭示了肿瘤内上皮-间质梯度的异质性	Truong Le, T.	PDF	N/A	Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient
高级卵巢透明细胞癌的空间转录组学分析揭示了肿瘤内上皮-间质梯度的异质性	Truong Le, T.	PDF	N/A	Spatial Transcriptomic Profiling Of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity In Epithelial-Mesenchymal Gradient
烟酰胺代谢重编程驱动胶质母细胞瘤细胞的可逆性衰老	Narayanan, A.	PDF	N/A	Nicotinamide Metabolism Reprogramming Drives Reversible Senescence of Glioblastoma Cells
空间生物学的保守原则定义了肿瘤异质性及对免疫治疗的反应	Behera, V.	PDF	N/A	Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapy
苦味受体激动剂可诱导甲状腺乳头状癌凋亡	Wei, K.	PDF	N/A	Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer
ALDH1亚型特异性抑制剂靶向三阴性乳腺癌中的关键细胞群体	PEREZ, M.	PDF	N/A	ALDH1 subtype-specific inhibitor targets key cell populations in triple negative breast cancer
Hv1质子通道缺陷增强巨噬细胞抗原呈递及胶质瘤中的抗肿瘤反应	Zheng, J.	PDF	N/A	Deficiency of Hv1 Proton Channel Enhances Macrophage Antigen Presentation and Anti-Tumor Responses in Glioma
人工选择与皮肤微生物群独立预测寄生虫抗性	Kramp, R. D.	PDF	N/A	Artificial Selection and the Skin Microbiome Independently Predict Parasite Resistance
邻接算法中的混合种群：一种五分类群的几何分析	Zhang, J. Z.	PDF	N/A	Admixed populations in the neighbor-joining algorithm: a geometric analysis with five taxa
通过位点特异性掺入基于转子的荧光非规范氨基酸，在活细胞中实时可视化蛋白质微环境变化，具有高空间分辨率	Yang, S.	PDF	N/A	Real-Time Visualization of Protein Microenvironment Changes with High Spatial Resolution in Live Cells via Site-Specific Incorporation of Rotor-Based Fluorescent Noncanonical Amino Acids
具有可调特性的双面蛋白质纳米材料的计算设计	Rankovic, S.	PDF	N/A	Computational design of bifaceted protein nanomaterials with tailorable properties
快速微流控灌注系统能够控制由Na+/H+交换体NHE1调节的细胞内pH动态变化。	Tran, Q. D.	PDF	N/A	Rapid microfluidic perfusion system enables controlling dynamics of intracellular pH regulated by Na+/H+ exchanger NHE1
p-ClustVal：一种新颖的p进制方法用于增强高维单细胞RNA测序数据的聚类分析	Sharma, P.	PDF	N/A	p-ClustVal: A Novel p-adic Approach for Enhanced Clustering of High-Dimensional scRNASeq Data
生成式人工智能在药物发现中的应用：基于GPT-2和LSTM模型的EGFR抑制剂设计	Dasser, O.	PDF	N/A	Generative AI for Drug Discovery: A GPT-2 and LSTM Based Models for Designing EGFR Inhibitors
利用SearchNovo弥合数据库搜索与从头肽段测序之间的差距	Xia, J.	PDF	N/A	Bridging the Gap between Database Search and De Novo Peptide Sequencing with SearchNovo
LP-Micro通过利用微生物生物标志物及其随时间变化的影响，提供可解释的疾病结果预测。	Dai, Y.	PDF	N/A	LP-Micro Offers Interpretable Disease Outcome Prediction by Leveraging Microbial Biomarkers and Their Time-Varying Effects
对人类蛋白质组功能注释的纵向分析揭示了持续的高偏差	Phan, A.	PDF	N/A	A Longitudinal Analysis of Function Annotations of the Human Proteome Reveals Consistently High Biases
使用群论和对称元素建模心电图（ECG）波形	Frueh, S. J.	PDF	N/A	Modeling Electrocardogram (ECG) Waveforms Using Group Theory and Symmetry Elements
CryoLike：一个用于冷冻电镜图像到结构似然计算的Python包	Tang, W. S.	PDF	N/A	CryoLike: A python package for cryo-electron microscopy image-to-structure likelihood calculations
特化细胞和转运蛋白介导慈鲷幼体皮肤吸收环境肽。	Con, P.	PDF	N/A	Specialized cells and transporters mediate integument-absorption of environmental peptides in cichlids larvae.
火星磁场和重力场对秀丽隐杆线虫多代的影响	Akinosho, A.	PDF	N/A	Effects of Martian magnetic and gravitational fields across multiple generations of the nematode C. elegans
冻结区动力学的数学建模：朝着在冷冻治疗中使用热成像仪的方向发展	Ivakhnenko, O. V.	PDF	N/A	Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy
竞争性互动塑造了跨物种的大脑动力学和计算能力	Luppi, A. I.	PDF	N/A	Competitive interactions shape brain dynamics and computation across species
纤维微观结构分位数（FMQ）回归：一种分析从外围到核心的白质束的新型统计方法	Lan, Z.	PDF	N/A	Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core
纤维微观结构分位数（FMQ）回归：一种分析从外围到核心的白质束的新型统计方法	Lan, Z.	PDF	N/A	Fiber Microstructure Quantile (FMQ) Regression: A Novel Statistical Approach for Analyzing White Matter Bundles from Periphery to Core
通过PANDORA-seq技术揭示的阿尔茨海默病小鼠模型中线粒体小RNA变化与溶酶体活性增加相关	Zhang, X.	PDF	N/A	Mitochondrial small RNA alterations associated with increased lysosome activity in an Alzheimer's Disease Mouse Model uncovered by PANDORA-seq
学术成就与心理健康：贫困儿童前额叶-顶叶-默认模式网络耦合的悖论	Pacheco, S.	PDF	N/A	Academic Success and Mental Health: The Paradox of Frontoparietal-Default Mode Network Coupling among Children Facing Poverty
可诱导的胰腺REG/Reg异构体，而非组成型异构体，受肠道微生物群和胰腺疾病调控。	Zhou, Y.	PDF	N/A	Inducible, but not constitutive, pancreatic REG/Reg isoforms are regulated by intestinal microbiota and pancreatic diseases
人类腺样体的单细胞转录组分析揭示了气道微褶细胞的分子特征	Alvarez-Arguedas, S.	PDF	N/A	Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells
在基因流动较高的局部适应种群中，遗传分化主要受限于染色体倒位和假定的着丝粒。	Akopyan, M.	PDF	N/A	Genetic differentiation is constrained to chromosomal inversions and putative centromeres in locally adapted populations with higher gene flow
利用病原体防御权衡管理作物害虫对生物防治产生抗性的风险。	Mangan, R. M.	PDF	N/A	Exploiting pathogen defence trade-offs to manage risks of crop pests evolving resistance to biocontrol.
对贝加尔湖海豹及其他海豹科动物进行全基因组重测序，以一窥其遗传多样性、种群历史及系统发育关系。	Nebenfuehr, M.	PDF	N/A	Whole-genome re-sequencing of the Baikal seal and other phocid seals for a glimpse into their genetic diversity, demographic history, and phylogeny
在单核苷酸分辨率下，人群之间人类肠道微生物组的基因组多样性和基础代谢变异	Dong, Q.	PDF	N/A	Genomic diversity and underlying metabolic variations of the human gut microbiome between populations at single nucleotide resolution
加拿大卡尔加里市弓河中微塑料的九个分离株的完整基因组序列	Goff, K. L.	PDF	N/A	Complete genome sequences of nine isolates from microplastics in the Bow River, Calgary, Canada
开发用于人C肽分泌的片上荧光各向异性免疫分析法揭示了示踪剂优化的通用路线图	Wang, Y.	PDF	N/A	Development of an on-chip fluorescence anisotropy immunoassay for human C-peptide secretion reveals a general roadmap for tracer optimization
多通道漏斗适应传感管（MFAST）用于寄生虫的简单和双检测	Peng, R.	PDF	N/A	Multi-Channel Funnel Adapted Sensing Tube (MFAST) for the Simple and Duplex Detection of Parasites
基于注意力机制的深度神经网络模型，用于从多组学数据中在单细胞水平检测顺式调控元件	Murakami, K.	PDF	N/A	An attention-based deep neural network model to detect cis-regulatory elements at the single-cell level from multi-omics data
ABCB4的膜依赖性动态变化及双重转运机制：分子动力学模拟的见解	Crespi, V.	PDF	N/A	Membrane-Dependent Dynamics and Dual Translocation Mechanisms of ABCB4: Insights from Molecular Dynamics Simulations
等离子体膜的纳米级曲率通过核变形和破裂调节机械适应性。	Francis, E. A.	PDF	N/A	Nanoscale curvature of the plasma membrane regulates mechanoadaptation through nuclear deformation and rupture
关联无序激活域集合与基因表达水平	Flores, E.	PDF	N/A	Correlating Disordered Activation Domain Ensembles with Gene Expression Levels
无标度群体行为和上皮活性固体中的巨幅波动	Shen, Y.	PDF	N/A	Scale-free flocking and giant fluctuations in epithelial active solids
电刺激期间猴子V1区局部场电位的层特异性动力学	Lee, S.	PDF	N/A	Layer-specific dynamics of local field potentials in monkey V1 during electrical stimulation
通过AFM纳米动态力学分析鉴定出的胶原超微结构粘弹性行为	Asgari, M.	PDF	N/A	Ultrastructural viscoelastic behavior of collagen identified by AFM nano-dynamic mechanical analysis
基于功能性单细胞方法理解恩杂鲁胺耐药性的发展	Xue, C.	PDF	N/A	Understanding the development of enzalutamide resistance based on a functional single-cell approach
氯胺酮代谢物（2R,6R）-羟基去甲氯胺酮诱导的海马突触快速增强持久地预处理突触可塑性	Brown, K. A.	PDF	N/A	RAPID HIPPOCAMPAL SYNAPTIC POTENTIATION INDUCED BY KETAMINE METABOLITE (2R,6R)-HYDROXYNORKETAMINE PERSISTENTLY PRIMES SYNAPTIC PLASTICITY
转录组分析揭示了牛结核病易感性的品种特异性免疫特征	Kumar, R.	PDF	N/A	Transcriptomic profiling identifies breed-specific immune signatures of Tuberculosis susceptibility in cattle
在啮齿动物中，背侧海马和腹侧海马分别靶向内侧前额叶皮层的不同细胞群体	Aleman-Andrade, P.	PDF	N/A	Dorsal-caudal and ventral hippocampus target different cell populations in the medial frontal cortex in rodents
针对乙酰基转移酶NAT10进行靶向治疗，可以纠正人类额颞叶神经元的病理变化，并在果蝇体内tau蛋白病变的模型中延长寿命。	Paonessa, F.	PDF	N/A	Targeting the acetyltransferase NAT10 corrects pathologies in human frontotemporal neurons and extends lifespan in an in vivo Drosophila tauopathy model
视交叉上核的连接组组织	Liu, J.	PDF	N/A	Connectomic Organization of the Suprachiasmatic Nucleus
探索在HIV-1感染的体内模型中，胞外囊泡、树突状细胞免疫受体与microRNA-155之间的关系，以理解疾病并开发新疗法	Boucher, J.	PDF	N/A	Exploring the Relationship Between Extracellular Vesicles, the Dendritic Cell Immunoreceptor and microRNA-155 in an In Vivo Model of HIV-1 Infection to Understand the Disease and Develop New Treatments
Cdc42的缺失导致小鼠视杯形态发生异常及小眼症	Hofstetter, K. S.	PDF	N/A	Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse
古老而依然存活的杨树克隆体“潘多”中的体细胞突变镶嵌图	Pineau, R.	PDF	N/A	Mosaic of Somatic Mutations in the Ancient and Still-Living Aspen Clone, Pando
十倍扩展的基质辅助激光解吸电离质谱成像技术，以500纳米分辨率对组织和细胞进行成像	Xie, C.	PDF	N/A	Ten-Fold Expansion MALDI Mass Spectrometry Imaging of Tissues and Cells at 500 nm Resolution
PSKH1激酶活性通过别构结合Ca2+传感器蛋白而受到差异性调节	Horne, C.	PDF	N/A	PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins
THRESHOLD：一种综合性的转录组分析工具，用于评估基因饱和度及其在疾病进展中的影响	Gammell, F. M.	PDF	N/A	THRESHOLD: A Comprehensive Transcriptomic Analysis Tool for Evaluating Gene Saturation and Impact in Disease Progression
利用原代人神经干细胞和祖细胞模拟胶质瘤的瘤内异质性	Gao, D.	PDF	N/A	Modeling Glioma Intratumoral Heterogeneity with Primary Human Neural Stem and Progenitor Cells
KRAS G12突变等位基因通过FOXO1调控谷氨酰胺代谢的差异性	Ber, S.	PDF	N/A	KRAS G12 mutant alleles differentially control glutamine metabolism via FOXO1
前额叶抑制在被动应对行为中的关键作用：慢性压力与速效抗抑郁药	Fong, T. H.	PDF	N/A	Key contribution of prefrontal inhibition to passive coping behaviour: chronic stress and fast-acting antidepressant
嗅觉中的数据科学	agarwal, v. K.	PDF	N/A	Data Science in Olfaction
scAGCI：一种基于锚点图的细胞聚类方法，用于从整合的单细胞RNA测序（scRNA-seq）和单细胞ATAC测序（scATAC-seq）数据中进行细胞聚类。	Dong, Y.	PDF	N/A	scAGCI: an anchor graph-based method for cell clustering from integrated scRNA-seq and scATAC-seq data
控制生物分子凝聚物中界面蛋白质的吸附、解吸和聚集	Visser, B.	PDF	N/A	Controlling interfacial protein adsorption, desorption and aggregation in biomolecular condensates
Capicua在德国小蠊卵巢中维持前后轴	Elshaer, N.	PDF	N/A	Capicua maintains anterior-posterior axis in Blattella germanica ovaries
温度依赖性和性别特异性的表型可塑性在Heliconius charithonia中	Seixas, F. A.	PDF	N/A	Temperature-dependent and sex-specific phenotypic plasticity in Heliconius charithonia
在分化中的晶状体纤维细胞中，核仁核糖体RNA的持续合成一直持续到突然的核降解，这是实现眼睛晶状体透明性所必需的。	Rayee, D.	PDF	N/A	Continuous nucleolar ribosomal RNA synthesis in differentiating lens fiber cells until abrupt nuclear degradation required for ocular lens transparency
整合的局部和系统性交流因素调控发育性造血过程中新生造血祖细胞的逃逸	Shalaby, C.	PDF	N/A	Integrated local and systemic communication factors regulate nascent hematopoietic progenitor escape during developmental hematopoiesis
环境线索影响河狸筑坝活动中建筑活动的时机和地点	Kennedy, J. R.	PDF	N/A	Environmental cues influence timing and location ofconstruction activity in a beaver damming complex
生态和社会因素导致埋葬甲虫中两性间的亲代抚育行为存在差异。	Ma, D.	PDF	N/A	Ecological and social factors lead to variation in parental care between sexes in a burying beetle
在序列学习任务中，人类是资源理性的预测者	Ferdinand, V.	PDF	N/A	Humans are resource-rational predictors in a sequence learning task
AnimalMotionViz：一种利用计算机视觉技术追踪和可视化动物运动模式的交互式软件工具	De Castro, A. L.	PDF	N/A	AnimalMotionViz: an interactive software tool for tracking and visualizing animal motion patterns using computer vision
执行控制可以查询隐藏的人类记忆	Zhao, C.	PDF	N/A	Executive control can query hidden human memories
人类前驱期和早期帕金森病及大鼠模型中的纵向神经黑色素变化	Perot, J.-B.	PDF	N/A	Longitudinal neuromelanin changes in prodromal and early Parkinson's disease in humans and rat model
诱导神经元的转录特征可区分病毒学抑制的HIV感染者与非HIV感染者	Ostermann, P. N.	PDF	N/A	A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV
骨髓源性的β-己糖胺酶对神经健康和溶酶体功能至关重要：对Sandhoff病的启示	Tsourmas, K. I.	PDF	N/A	Myeloid-derived β-hexosaminidase is essential for neuronal health and lysosome function: implications for Sandhoff disease
严重脊髓性肌萎缩症中D-和L-氨基酸失衡调节谷氨酸能神经传递。	Hassan, A.	PDF	N/A	Dysregulated balance of D- and L-amino acids modulating glutamatergic neurotransmission in severe spinal muscular atrophy.
线性化与预测：一种基于储备计算的脑数字孪生方法	Di Antonio, G.	PDF	N/A	Linearizing and forecasting: a reservoir computing route to digital twins of the brain
视觉工作记忆中边界或独立特征的保持是任务依赖的	Cao, R.	PDF	N/A	Maintenance of Bound or Independent Features in Visual Working Memory is Taskdependent
间歇性干扰电流刺激对迷走神经中器官特异性纤维时空激活的控制	Rossetti, N.	PDF	N/A	Control of spatiotemporal activation of organ-specific fibers in the vagus nerve by intermittent interferential current stimulation
捕捉生物物理神经模型中的动态涌现结构	Milinkovic, B.	PDF	N/A	Capturing the emergent dynamical structure in biophysical neural models
捕捉生物物理神经模型中的新兴动力学结构	Milinkovic, B.	PDF	N/A	Capturing the emergent dynamical structure in biophysical neural models
内皮细胞Nrf2调控系统性损伤后的神经炎症	Zou, H.	PDF	N/A	Endothelial cell Nrf2 controls neuroinflammation following a systemic insult
Opto2P-FCM：一种基于MEMS的微型双光子显微镜，具有双光子图案化光遗传刺激功能	Futia, G. L.	PDF	N/A	Opto2P-FCM: A MEMS based miniature two-photon microscope with two-photon patterned optogenetic stimulation
在蝙蝠卡罗利亚（Carollia perspicillata）中，听觉阈值因性别而异，但与年龄无关。	Molano, O.	PDF	N/A	Hearing thresholds in the bat Carollia perspicillata vary by sex but not age
语音编码在衰老和失语症中的时空动力学	Kries, J.	PDF	N/A	The spatio-temporal dynamics of phoneme encoding in aging and aphasia
利用空间转录组学和类器官技术定义猪母胎界面细胞多样性	McCutcheon, C.	PDF	N/A	Defining Cellular Diversity at the Swine Maternal-Fetal Interface Using Spatial Transcriptomics and Organoids
自噬在生殖系干细胞中是可有可无的，但在果蝇卵巢生态位中维持帽细胞则需要自噬。	Nilangekar, K. S.	PDF	N/A	Autophagy is dispensable in germline stem cells but is required in the cap cells for their maintenance in the Drosophila ovarian niche
干细胞和祖细胞的增殖由细胞类型特异性的周期蛋白D基因独立调控。	Lush, M. E.	PDF	N/A	Stem and progenitor cell proliferation are independently regulated by cell type-specific cyclinD genes
细胞增殖的局部控制是斑马鱼神经丘再生的基础	Lavalle, N. G.	PDF	N/A	Local control of cellular proliferation underlies neuromast regeneration in zebrafish
氧气水平改变牛早期胚胎的能量代谢	Boskovic, N.	PDF	N/A	Oxygen level alters energy metabolism in bovine preimplantation embryos
背外侧前额叶皮层神经活动的损伤在帕金森病早期即出现	Hjelle, N.	PDF	N/A	Impairment of Neuronal Activity in the Dorsolateral Prefrontal Cortex Occurs Early in Parkinsonism
星形胶质细胞TrkB.T1缺陷破坏了谷氨酸能突触的形成以及星形胶质细胞与突触的相互作用。	Pinkston, B. T. C.	PDF	N/A	Astrocyte TrkB.T1 deficiency disrupts glutamatergic synaptogenesis and astrocyte-synapse interactions.
Shc1与Frs2和Shp2合作，在FGF诱导的晶状体发育中招募Grb2	Wang, Q.	PDF	N/A	Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development
经皮迷走神经刺激在感知决策过程中提高了错误后的准确性	Su, S.	PDF	N/A	Transcutaneous Vagus Nerve Stimulation Boosts Post-Error Accuracy During Perceptual Decision-Making
针对果蝇中央复合体的细胞类型特异性驱动线及其用于研究神经肽表达和睡眠调控的应用	Wolff, T.	PDF	N/A	Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation
未甲基化全突变携带者的转录组分析表明TET3在脆性X综合征中FMR1 CGG重复扩增甲基化动力学中的作用	Farmiloe, G.	PDF	N/A	Transcriptomic profiling of unmethylated full mutation carriers implicates TET3 in FMR1 CGG repeat expansion methylation dynamics in Fragile X syndrome
利用生长素诱导降解子2技术揭示单个突触快速蛋白质清除的急性后果	Elbaum, L.	PDF	N/A	Revealing Acute Consequences of Rapid Protein Elimination at Individual Synapses using Auxin-Inducible Degron 2 Technology
通过自我调节体感活动增强人体感觉运动整合	Iwama, S.	PDF	N/A	Enhanced human sensorimotor integration via self-modulation of the somatosensory activity
使用具有分化簇基因启动子的病毒载体，以靶向大脑中的特定细胞类型	Uesaka, N.	PDF	N/A	Viral vectors with cluster of differentiation gene promoters to target specific cell types in the brain
阿尔茨海默病5XFAD小鼠的空间记忆通过XPO1抑制剂KPT-330得到增强	Wong, S. Q.	PDF	N/A	Spatial memory in Alzheimer's disease 5XFAD mice is enhanced by XPO1 inhibitor KPT-330
视觉对象优化头部方向编码	Siegenthaler, D.	PDF	N/A	Visual objects refine head direction coding
代理体感图谱平铺视觉皮层	Hedger, N.	PDF	N/A	Vicarious Somatotopic Maps Tile Visual Cortex
实验室间微球免疫测定法的协调：用于干燥血斑和口腔液体中SARS-CoV-2抗体检测	DeRosa, K. L.	PDF	N/A	Inter-laboratory harmonization of microsphere immunoassays for SARS-CoV-2 antibody detection in dried blood spots and oral fluids
工程化蛋白质去稳定化逆转了内在免疫逃避，以实现候选疫苗泛株KSHV和SARS-CoV-2抗原	Wan, L.	PDF	N/A	Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens
真菌性脑膜炎病原体的表型景观揭示了其独特的生物学特性	Boucher, M.	PDF	N/A	Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology
单细胞转录组学揭示了皮肤细胞特异性的抗真菌免疫反应，以及新兴真菌病原体白色念珠菌的IL-1Ra- IL-1R免疫逃避策略	Balakumar, A.	PDF	N/A	Single-Cell Transcriptomics Unveils Skin Cell Specific Antifungal Immune Responses and IL-1Ra- IL-1R Immune Evasion Strategies of Emerging Fungal Pathogen Candida auris
MIIST305 能够减轻胃肠道急性放射综合征损伤，并改善放射引起的肠道菌群失调。	Mitra, D.	PDF	N/A	MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosis
一种针对微生物组衍生疗法的靶向发现和表征的理性方法	Krause, L.	PDF	N/A	A rational approach for the targeted discovery and characterisation of microbiome-derived therapeutics
HPAIV H5N1在生牛奶、废水和表面上的环境稳定性	Kaiser, F.	PDF	N/A	Environmental stability of HPAIV H5N1 in raw milk, wastewater and on surfaces
进化距离较远的细菌之间抗生素抗性基因的转移	Parras-Molto, M.	PDF	N/A	The transfer of antibiotic resistance genes between evolutionary distant bacteria
被遗忘的迷幻剂：2C-B和psilocybin给药后脑组织的空间时间映射	Mallaroni, P.	PDF	N/A	The forgotten psychedelic: Spatiotemporal mapping of brain organisation following the administration of 2C-B and psilocybin
功能性超声成像揭示了临床脊髓刺激的激活特性	Lim, K.	PDF	N/A	Functional Ultrasound Imaging Reveals Activation Properties of Clinical Spinal Cord Stimulation
人类在嘈杂环境中对语音感知的神经功能和因果机制	Ceravolo, L.	PDF	N/A	Functional and causal neural mechanisms of human voice perception in noisy situations
基于连接组学的预测模型：一般和特定认知控制的预测模型	Qu, S.	PDF	N/A	Connectome-based Predictive Models of General and Specific Cognitive Control
人类短连合纤维比长纤维更细，且髓鞘化程度较低。	Ruthig, P.	PDF	N/A	Human short association fibers are thinner and less myelinated than long fibers
一种主动电感应的端到端模型	Turcu, D.	PDF	N/A	An end-to-end model of active electrosensation
帕金森病在运动准备期间扰乱了前辅助运动区的神经调节	Hendrix, C. M.	PDF	N/A	Parkinsonism disrupts neuronal modulation in the pre-supplementary motor area during movement preparation
Arc通过细胞外囊泡介导细胞间tau传递	Tyagi, M.	PDF	N/A	Arc mediates intercellular tau transmission via extracellular vesicles
Bcl11b通过细胞自主、非细胞自主和亚细胞机制调控小脑下投射神经元的轴突发育	Itoh, Y.	PDF	N/A	Bcl11b orchestrates subcerebral projection neuron axon development via cell-autonomous, non-cell-autonomous, and subcellular mechanisms
听觉带状皮层中对侧编码的分层涌现	Johnson, J. S.	PDF	N/A	Hierarchical emergence of opponent coding in auditory belt cortex
大麻二酚逆转了精神分裂症小鼠模型中的小胶质细胞激活、小清蛋白中间神经元和神经元周围网的损失。	Rodrigues da Silva, N.	PDF	N/A	Cannabidiol reverses microglia activation and loss of parvalbumin interneurons and perineuronal nets in a mouse model of schizophrenia
催产素神经元在社交和非社交环境中，通过状态依赖的信号传递，调控产热和行为觉醒的转变。	Vandendoren, M.	PDF	N/A	Oxytocin neurons signal state-dependent transitions to thermogenesis and behavioral arousal in social and non-social settings.
关系是资源还是负担？依恋风格、关系质量和伴侣间应对与浪漫伴侣在场时急性心理社会压力的关联	Gallistl, M.	PDF	N/A	Relationship as resource or burden? Associations of attachment style, relationship quality and dyadic coping with acute psychosocial stress in the presence of the romantic partner
α-突触核蛋白病理进展的网络分析揭示p21激活激酶作为脆弱性的调节因子	Vatsa, N.	PDF	N/A	Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
一种具有增强信噪比性能的128通道接收阵列，用于10.5特斯拉脑部成像	Lagore, R. L.	PDF	N/A	A 128-channel receive array with enhanced SNR performance for 10.5 tesla brain imaging
40 Hz光刺激恢复了阿尔茨海默病模型小鼠早期脑动力学改变及联想记忆	Aguilera, M.	PDF	N/A	40 Hz light stimulation restores early brain dynamics alterations and associative memory in Alzheimer's disease model mice
共享和个体体验的神经相关性	Coppola, P.	PDF	N/A	The neural correlates of shared and individual experience
伏隔核中的5-HT2C受体限制了MDMA的奖赏效应。	Pomrenze, M. B.	PDF	N/A	5-HT2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA
适当选择参考电极并进行重新参考，以减轻单脉冲电刺激数据中的偏差	Huang, H.	PDF	N/A	Proper reference selection and re-referencing to mitigate bias in single pulse electrical stimulation data
干扰素介导的自然杀伤细胞激活与SARS-CoV-2感染期间有限的病毒中和广度相关	de los Rios Kobara, I.	PDF	N/A	Interferon-mediated NK cell activation is associated with limited neutralization breadth during SARS-CoV-2 infection
Wag31，一种膜系绳，对分枝杆菌中的脂质稳态至关重要。	Kapoor, Y.	PDF	N/A	Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria
鱼类作为河流抗菌素耐药性监测的哨兵效果不佳	Tskhay, F.	PDF	N/A	Fish are poor sentinels for surveillance of riverine AMR
多酚重塑微生物群落可减少甲烷排放	McGivern, B. B.	PDF	N/A	Polyphenol rewiring of the microbiome reduces methane emissions
空间的重要性：受移动限制的虚拟行人会影响个人的避让行为	Nikmanesh, M.	PDF	N/A	Space matters: virtual pedestrians with mobility constraints affect individuals' avoidance behaviours
酮症通过改善生物能量代谢提升抗氧化能力并增强神经功能：一项1H磁共振波谱研究	van Nieuwenhuizen, H.	PDF	N/A	Ketosis Elevates Antioxidants and Enhances Neural Function Through Improved Bioenergetics: A 1H MR Spectroscopy Study
活体双光子荧光显微镜中的自适应光学校正与神经场	Kang, I.	PDF	N/A	Adaptive optical correction in in vivo two-photon fluorescence microscopy with neural fields
局部姿势变化会在关节、躯干和面部周围引发广泛而多样的皮肤伸展。	Rupani, M.	PDF	N/A	Local postural changes elicit extensive and diverse skin stretch around joints, on the trunk, and the face
基于生物性别（男性与女性）对受试者进行分组的局限性及新方法：从伏隔核核心内多巴胺诱导的精神兴奋剂活性中获得的启示。	Job, M. O.	PDF	N/A	Limitations of grouping subjects based on biological sex (males versus females) and a new approach: insights from intra-nucleus accumbens core dopamine-induced psychostimulant activity.
针对小麦叶际细菌的新型噬菌体携带DNA修饰和单链断裂	Dougherty, P. E.	PDF	N/A	Novel bacteriophages targeting wheat phyllosphere bacteria carry DNA modifications and single-strand breaks
通过恢复衰老的成骨前体细胞来促进骨修复	Reeves, J.	PDF	N/A	Rejuvenating aged osteoprogenitors for bone repair
Zyxin的缺失减少了内皮炎症并减轻了动脉粥样硬化	Huang, H.	PDF	N/A	Deletion of Zyxin Reduces Endothelial Inflammation and Mitigates Atherosclerosis
在侵袭和相关吞噬过程中，会形成一个独特的PI(4,5)P2区室。	Durgan, J.	PDF	N/A	A distinctive PI(4,5)P2 compartment forms during entosis and related engulfment processes
由于上皮-间质转化导致的化疗耐药性是由异常的脂质代谢平衡引起的。	Matsumoto, A.	PDF	N/A	Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance
NIPBL和STAG1通过提供差异化的DNA-凝聚素亲和力来实现环挤压。	van Wee, R.	PDF	N/A	NIPBL and STAG1 enable loop extrusion by providing differential DNA-cohesin affinity
# BioRxiv 2024-10-21 Papers

标题	作者	PDF链接	代码仓库	Title
大学考试与心理社会压力：对学生皮质醇节律性的影响	Borghi, F.	PDF	N/A	University Exams and Psychosocial Stress: Effects on Cortisol Rhythmicity in Students
通过木质素复合物持续清除活性氧并改善细胞周围氧合作用，挽救HIF-1α和VEGF水平，从而促进糖尿病伤口的新血管生成和愈合。	Jung, J. P.	PDF	N/A	Sustained ROS Scavenging and Pericellular Oxygenation by Lignin Composites Rescue HIF-1α and VEGF Levels to Improve Diabetic Wound Neovascularization and Healing
血清素调节非快速眼动睡眠期间齿状回的次慢振荡	Turi, G. F.	PDF	N/A	Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep
机器学习预测酶的最适pH值	Gado, J. E.	PDF	N/A	Machine learning prediction of enzyme optimum pH
基于YAP驱动的口腔上皮干细胞恶性重编程的单细胞分辨率研究	Faraji, F.	PDF	N/A	YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution
预测亲和力通过同源性（PATH）：利用持久同源性进行可解释的结合亲和力预测	Long, Y.	PDF	N/A	Predicting Affinity Through Homology (PATH): Interpretable Binding Affinity Prediction with Persistent Homology
自然杀伤细胞的细胞毒性塑造了B细胞白血病的克隆进化	Buri, M. C.	PDF	N/A	Natural killer cell cytotoxicity shapes the clonal evolution of B cell leukaemia
神经纤毛蛋白-1是NGF和TrkA引发疼痛的共受体。	Peach, C. J.	PDF	N/A	Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain
一类新型的人类CpG岛启动子，具有灵长类特异性重复序列	Mohan, K. N.	PDF	N/A	A new class of human CpG island promoters with primate-specific repeats
正交化的人类蛋白酶调控分泌信号	Aldrete, C. A.	PDF	N/A	Orthogonalized human protease control of secreted signals
无性生殖的旋口虫Adineta vaga中的跨代染色体修复	Houtain, A.	PDF	N/A	Transgenerational chromosome repair in the asexual bdelloid rotifer Adineta vaga
疟原虫电子传递链中细胞色素c和c1的生物发生	Garcia-Guerrero, A. E.	PDF	N/A	Biogenesis of cytochromes c and c1 in the electron transport chain of malaria parasites
致癌性STIL介导的BRCA1功能丧失导致DNA损伤和中心体扩增	Sanghi, S.	PDF	N/A	Oncogenic STIL-mediated loss of BRCA1 functionality causes DNA damage and centrosome amplification
童年虐待相关的腹内侧前额叶皮层周围神经网增加中微胶质细胞参与的证据	Belliveau, C.	PDF	N/A	Evidence of microglial involvement in the childhood abuse-associated increase in perineuronal nets in the ventromedial prefrontal cortex
通过综合转录组和表观基因组分析揭示癌症驱动基因——Moonlight	Nourbakhsh, M.	PDF	N/A	Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight
投射至腹侧CA1区的内梨状神经元是识别记忆的关键节点。	Yamawaki, N.	PDF	N/A	Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory
三部分ATP非依赖性周质（TRAP）转运蛋白结合Neu5Ac的分子决定因素	Goyal, P.	PDF	N/A	Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter
墨西哥洞穴鱼在短睡眠状态下表现出升高的DNA损伤，但无衰老迹象	Lloyd, E.	PDF	N/A	Elevated DNA Damage without signs of aging in the short-sleeping Mexican Cavefish
SCREP：通过药理基因组嵌入增强的元预训练和少样本迁移学习实现单细胞药物反应预测	Ge, S.	PDF	N/A	SCREP: Towards Single-Cell Drug Response Prediction by Pharmacogenomic Embedding Enhanced Meta-Pretraining and Few-Shot Transfer Learning
T细胞上PIK3IP1/TrIP的下调受TCR信号强度、PKC以及金属蛋白酶介导的切割调控。	Murter, B. M.	PDF	N/A	Downregulation of PIK3IP1/TrIP on T cells is controlled by TCR signal strength, PKC, and metalloprotease-mediated cleavage
酵母剪接因子Fyv6对3'剪接位点选择的调控	Senn, K.	PDF	N/A	Control of 3' splice site selection by the yeast splicing factor Fyv6
在阿尔茨海默病的小鼠模型中，记忆编码和巩固所依赖的海马功能障碍先于明显的β淀粉样蛋白沉积发生。	Li, H.	PDF	N/A	Impaired hippocampal functions underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of Alzheimer's disease
前生物气体流动环境能够实现等温核酸复制	Schwintek, P.	PDF	N/A	Prebiotic gas flow environment enables isothermal nucleic acid replication
样式偏转由叶序的左右手性和具有镜像花朵的物种中生长素诱导的细胞伸长差异决定。	Robertson, C.	PDF	N/A	Style deflection is determined by the handedness of phyllotaxis and auxin-induced differential cell elongation in a species with mirror-image flowers
嗅觉组合编码支持秀丽隐杆线虫的风险-回报决策	Saad, M. Z. H.	PDF	N/A	Olfactory combinatorial coding supports risk-reward decision making in C. elegans
陆地植物的核基因组和细胞器基因组的进化速率是相互关联的。	Asar, Y.	PDF	N/A	Evolutionary rates of nuclear and organellar genomes are linked in land plants
使用生成对抗网络（GANs）对长基因序列进行潜在生成建模	Szatkownik, A.	PDF	N/A	Latent generative modeling of long genetic sequences with GANs
熵产生限制了基因调控中的信息传递	Gehri, M.	PDF	N/A	Entropy production constrains information throughput in gene regulation
BioLP-bench：评估大型语言模型对生物实验室协议的理解能力	Ivanov, I.	PDF	N/A	BioLP-bench: Measuring understanding of biological lab protocols by large language models
在学习过程中，丘脑核团与皮层网络之间的功能连接发生了渐进性变化。	Jarrett, C. E.	PDF	N/A	Progressive changes in functional connectivity between thalamic nuclei and cortical networks across learning
用于预测转录组结构的长上下文RNA基础模型	Saberi, A.	PDF	N/A	A long context RNA foundation model for predicting transcriptome architecture
大脑活动能够区分同一环境的声学模拟	Matten, V. G.	PDF	N/A	Brain activity discriminates acoustic simulations of the same environment
大脑活动能够区分同一环境的声学模拟	Matten, V. G.	PDF	N/A	Brain activity discriminates acoustic simulations of the same environment
转录依赖的移植染色体在人工细胞中的膨胀	Greiss, F.	PDF	N/A	Transcription-dependent swelling of a transplanted chromosome in an artificial cell
解开睫状层的秘密：睫状糖萼的高分辨率结构与功能	Hoepfner, L. M.	PDF	N/A	Unwrapping the ciliary coat: high-resolution structure and function of the ciliary glycocalyx
使用合成轴突形态生成全脑连接组	Petkantchin, R.	PDF	N/A	Generating brain-wide connectome using synthetic axonal morphologies
PROPERMAB：一种综合框架，利用机器学习进行抗体可开发性的计算机预测	Li, B.	PDF	N/A	PROPERMAB: an integrative framework for in silico prediction of antibody developability using machine learning
冷冻电子断层扫描揭示了黄病毒的复制、出芽和成熟过程的耦合关系。	Dahmane, S.	PDF	N/A	Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation
褐藻门三角褐指藻Seipin同源基因的功能研究揭示了硅藻脂滴生物发生过程的独特特征。	Le Moigne, D.	PDF	N/A	Functional study of Phaeodactylum tricornutum Seipin homolog highlights unique features of lipid droplets biogenesis in diatoms.
单羧酸转运蛋白转运甲状腺素分子机制	Tassinari, M.	PDF	N/A	Molecular mechanism of thyroxine transport by monocarboxylate transporters
开发并验证了一种开源的“手性判断任务”，适用于面对面和在线研究	Moreno-Verdu, M.	PDF	N/A	Development and validation of an open-source Hand Laterality Judgement Task for in-person and online studies
通过解决GPT不准确的回答并进行情境基准测试来创建生物医学知识库	Darnell, S. S.	PDF	N/A	Creating a biomedical knowledge base by addressing GPT inaccurate responses and benchmarking context
在异种Caenorhabditis胚胎中，杂交不亲和性在一细胞阶段显现。	Bloom, J.	PDF	N/A	Hybrid incompatibility emerges at the one-cell stage in interspecies Caenorhabditis embryos
ISG15在癌症生物学中的作用：在泛癌背景下系统评估ISG15表达及其分子相互作用	Chatterjee, S.	PDF	N/A	The Role of ISG15 in Cancer Biology: Systematic Evaluation of ISG15 Expression and Its Molecular Interactions in a Pan-Cancer Context
ZNFX1是一种新型主调控因子，参与癌症中表观遗传诱导的病原体模拟和炎症小体信号传导	Stojanovic, L.	PDF	N/A	ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer
生物科学博士在出版方面存在明显的性别和种族/族裔差异模式。	Azurdia, D. E.	PDF	N/A	Distinct patterns of bioscience doctoral publication disparities by gender and race/ethnicity
使用增强型SCas12a检测方法实现高结构RNA的无扩增精确检测	Zhang, J.	PDF	N/A	Precise amplification-free detection of highly structured RNA with an enhanced SCas12a assay
利用GPT-4自动整理泛素-蛋白酶体系统中的E3-底物关系	Zhang, Z.	PDF	N/A	Harnessing GPT-4 for Automated Curation of E3-Substrate Relationships in the Ubiquitin-Proteasome System
体内功能分析与人类Glp1r A316T变异体的结构特征	El Eid, L.	PDF	N/A	In vivo functional profiling and structural characterisation of the human Glp1r A316T variant
通过空间蛋白质组学揭示初级纤毛的内在多样性	Lundberg, E.	PDF	N/A	Intrinsic Diversity in Primary Cilia Revealed Through Spatial Proteomics
依赖于Ca2+的囊泡和非囊泡脂质转移控制低渗质膜扩张	Mu, B.	PDF	N/A	Ca2+-dependent vesicular and non-vesicular lipid transfer controls hypoosmotic plasma membrane expansion
复制依赖性组蛋白（Repli-Histo）标记在活体人类细胞中解析常染色质/异染色质的物理特性。	Minami, K.	PDF	N/A	Replication-dependent histone (Repli-Histo) labeling dissects the physical properties of euchromatin/heterochromatin in living human cells.
使用webKnossos在电子显微镜体积中高效地进行全细胞线粒体映射	Jiang, Y.	PDF	N/A	Efficient cell-wide mapping of mitochondria in electron microscopic volumes using webKnossos
在秀丽隐杆线虫卵母细胞中，减数分裂I和II之间的染色体被一个细胞质分裂囊泡所包围。	El Mossadeq, L.	PDF	N/A	An interkinetic envelope surrounds chromosomes between meiosis I and II in C. elegans oocytes
Sec14L6是一种促进脂滴形成的PS和PI4P转运蛋白。	zhou, t.	PDF	N/A	Sec14L6 is a PS and PI4P transporter that promotes lipid droplet formation
哺乳动物细胞核内厚横纹线状纤维的检测与电子显微镜研究	Mosevitsky, M. I.	PDF	N/A	Detection and electron microscopic study of thick cross-striated linear fibrils in mammalian cell nuclei
在果蝇雄性和雌性的连续同源附肢发育过程中重新连接的基因相互作用	Ridgway, A. M.	PDF	N/A	Rewired gene interactions during development of serially homologous appendages in male and female Drosophila
miR-210基因座缺失破坏细胞稳态；一项综合遗传学研究	Preda, M. B.	PDF	N/A	miR-210 locus deletion disrupts cellular homeostasis; an integrated genetic study
从哔哔声到街道：揭示听觉情境中的感官输入与相关性	Korte, S.	PDF	N/A	From Beeps to Streets: Unveiling Sensory Input and Relevance Across Auditory Contexts
光学模糊对ON和OFF视觉通路的影响不同	Pons, C.	PDF	N/A	Optical blur affects differently ON and OFF visual pathways
岛屿杂交蝴蝶谱系的起源	Boman, J.	PDF	N/A	On the origin of an insular hybrid butterfly lineage
植物相关泛菌中质粒驯化的演化：大规模获得遗传冗余后伴随差异性基因丢失	Picazo, D. R.	PDF	N/A	Evolution of plasmid domestication in plant-associated Pantoea: massive gain of genetic redundancy followed by differential gene loss
大麻二酚（CBD）增强了雌性和雄性小鼠下丘脑-垂体-肾上腺（HPA）轴反应性的生理和行为标志。	Jenkins, B. W.	PDF	N/A	Cannabidiol (CBD) potentiates physiological and behavioral markers of hypothalamic-pituitary-adrenal (HPA) axis responsivity in female and male mice
使用HPM Live μ的Live-HPF CLEM：在每个干草堆中找回所有针。CLEM的最后前沿。	Heiligenstein, X.	PDF	N/A	Live-HPF CLEM using the HPM Live μ: Finding back all needles in every haystack. The last frontier in CLEM
TFAP2C和HNRNPK调控mTOR细胞代谢及朊病毒传播	Sellitto, S.	PDF	N/A	TFAP2C and HNRNPK control mTOR cell metabolism and prion propagation
顶端网格蛋白包被的胞吞凹陷控制上皮微绒毛的生长和大小	Perkins, O. L.	PDF	N/A	Apical clathrin-coated endocytic pits control the growth and size of epithelial microvilli
在T细胞群中出现了协同运动，但在中性粒细胞群中则没有出现。	Wortel, I. M. N.	PDF	N/A	Cooperative motility emerges in crowds of T cells but not neutrophils
主题使用反向相关法改进听觉表征的特征描述指南	Gezae, G. W.	PDF	N/A	Subject Instructions for Improved Characterization of Auditory Representations Using Reverse Correlation
lucie: 一个改进的用于从UCI机器学习库加载数据集的Python包	Ge, K.	PDF	N/A	lucie: An Improved Python Package for Loading Datasets from the UCI Machine Learning Repository
在使用readmers和hapmers评估牛津纳米孔测序读取错误纠正后的相位切换时	Elbers, J. P.	PDF	N/A	Using readmers and hapmers in assessing phase switching after read error correction of Oxford Nanopore Sequences
解密基本原子相互作用以统一生成分子对接与设计	Peng, X.	PDF	N/A	Decipher Fundamental Atomic Interactions to Unify Generative Molecular Docking and Design
癌症相关脂肪细胞通过FGF21驱动的脂肪分解介导CD8+T细胞功能障碍	Dalangood, S.	PDF	N/A	Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis
烟草烟雾暴露是头颈部癌症中氧化应激反应和免疫功能改变的驱动因素。	Sandulache, V. C.	PDF	N/A	Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer
转录组分析揭示了一群先前未知的Cdkn2a阳性肿瘤相关巨噬细胞，存在于侵袭性脑癌中。	Melo dos Santos, L. S.	PDF	N/A	Transcriptional profiling reveals a previously unknown population of Cdkn2a-positive tumor-associated macrophages in aggressive brain cancer
经皮递送的超可变形阳离子脂质体复合物miR211-5p（UCL-211）稳定了BRAFV600E+黑色素细胞痣	Chhibber, T.	PDF	N/A	Transdermal Delivery of Ultradeformable Cationic Liposomes Complexed with miR211-5p (UCL-211) Stabilizes BRAFV600E+ Melanocytic Nevi
热带气候下叶菜类蔬菜的氮离子组动态	Shenhar, I.	PDF	N/A	Nitrogen ionome dynamics on leafy vegetables in tropical climate
解决光暗转换时非光化学淬灭的非常规信号	Lam, L.	PDF	N/A	Resolving an unconventional non-photochemical quenching signature at the light-to-dark transition
构建脓毒症模型：数据整合揭示了严重铜绿假单胞菌感染的致病机制。	Messina, F.	PDF	N/A	Building a model of sepsis: data integration unravels pathogenic mechanisms in severe P. aeruginosa infections.
朝向生物分子凝聚体中集体相互作用的通用模型	Fuxreiter, M.	PDF	N/A	Towards universal models for collective interactions in biomolecular condensates
多时间尺度神经适应支撑长期肌肉骨骼重塑。	philipp, R.	PDF	N/A	Multi-timescale neural adaptation underlying long-term musculoskeletal reorganization.
新型FKBP12配体MP-004的局部给药可改善视网膜色素变性模型中的视网膜功能和结构。	Lara-Lopez, A.	PDF	N/A	Topical administration of novel FKBP12 ligand MP-004 improves retinal function and structure in retinitis pigmentosa models.
六种腺相关病毒载体血清型在小鼠下丘脑和大脑中的比较分析	Witteveen, I.	PDF	N/A	Comparative analysis of six adeno-associated viral vector serotypes in mouse inferior colliculus and cerebellum
泡沫状小胶质细胞与多发性硬化症进展中的氧化脂质相关	van der Vliet, D.	PDF	N/A	Foamy microglia link oxylipins to disease progression in multiple sclerosis
μ和δ阿片受体通过不同的细胞和分子机制调节前额叶皮层内的抑制作用	Cole, R. H.	PDF	N/A	Mu and Delta Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms
灰葡萄孢菌（Botrytis cinerea）中缺乏植原毒素生产能力的突变体的毒力丧失，可以通过修改接种培养基来恢复。	Qin, S.	PDF	N/A	Loss of virulence of Botrytis cinerea mutants defective in phytotoxin production is restored by modifying inoculation medium
通过刺激血流介导的血管融合，实现Galen静脉畸形血管的逆转	Martin-Valiente, E.	PDF	N/A	Reversal of vein of Galen aneurysmal malformation by stimulation of flow-mediated vessel fusion
模拟欧洲人畜共患脑炎（TBE）风险在时空上的年度变化	Dagostin, F.	PDF	N/A	Modeling the spatio-temporal annual changes in human tick-borne encephalitis (TBE) risk in Europe
模拟气候变暖情景导致独居蜂的羽化时间提前和体重减轻增加，但对越冬存活率没有影响。	Möllmann, J. S.	PDF	N/A	Simulated climate warming scenarios lead to earlier emergence and increased weight loss but have no effect on overwintering survival in solitary bees
树冠的自修剪受功能策略和邻域相互作用的影响。	Kothari, S.	PDF	N/A	Self-pruning in tree crowns is influenced by functional strategies and neighborhood interactions
磷的可用性作为温带生物多样性草本植被中营养限制的主要决定因素	Van Sundert, K.	PDF	N/A	Phosphorus availability as the primary determinant of nutrient limitation in temperate biodiverse herbaceous vegetation
进化宏观生态学：在基于过程、前瞻时间的模拟模型中更明确地纳入系统发育信息	Culshaw, V.	PDF	N/A	Evolutionary macroecology: Incorporating phylogenetic information more explicitly into process-based, forward time, simulation models
广食性微生物捕食者——盘基网柄菌（Dictyostelium discoideum）的猎物吸引力	Shreenidhi, P. M.	PDF	N/A	Prey attraction in a generalist microbial predator, Dictyostelium discoideum
在多维连续空间中建立本地适应的等位基因	Sakamoto, T.	PDF	N/A	Establishment of a locally adaptive allele in multidimensional continuous space
rs2069845多态性与全关节置换术期间IL-6和可溶性IL-6受体水平相关。	Anderson, K. D.	PDF	N/A	Polymorphisms in rs2069845 are associated with IL-6 and soluble IL-6 receptor levels during total joint replacement
450K和EPIC v2.0阵列之间的时间性和生物性衰老的兼容性和比较分析	De Pourcq, S.	PDF	N/A	Compatibility and comparative analysis of chronological and biological aging between the legacy 450K and the EPIC v2.0 arrays
对从腹泻患者中分离出的多重耐药粘质沙雷菌株IU-BTGE-M-3的比较基因组研究揭示了抗生素耐药性特征	Hossain, M. S.	PDF	N/A	Comparative Genome Study of Multidrug-resistant Serratia marcescens strain IU-BTGE-M-3 Isolated from a Diarrheal Patient Reveals Antibiotic Resistance Profile
表达驱动的遗传依赖性揭示了精准医疗的目标	Elmas, A.	PDF	N/A	Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine
前额叶皮层缺陷是创伤后应激障碍的一个假定易感因素	Nalloor, R. I.	PDF	N/A	Prefrontal Cortical Deficits are a Putative Susceptibility Factor for PTSD
ProtNote：一种用于蛋白质功能注释的多模态方法	Char, S.	PDF	N/A	ProtNote: a multimodal method for protein-function annotation
跑步时缩短飞行时间会减少胫腓骨应变：有限元分析	Khassetarash, A.	PDF	N/A	Reducing flight time during running decreases tibial-fibular strains: a finite element analysis
受物理启发的模型对接配体复合物精度估计器	Bae, B.	PDF	N/A	Physics-inspired accuracy estimator for model-docked ligand complexes
使用惯性矩张量分析对肺癌候选基因进行优先排序	Dwivedi, A.	PDF	N/A	Prioritization of Lung Cancer Candidate Genes using Moment of Inertia Tensor Analysis
组合连锁不平衡与连锁分析（cLDLA）：在生物信息学工作流程中实现一种强大的方法，用于识别复杂性状的遗传基础。	Upadhyay, M.	PDF	N/A	Combined Linkage Disequilibrium and Linkage Analysis (cLDLA): implementation of a powerful approach to identify the genetic basis of complex traits in a bioinformatics workflow.
表面活性剂和成膜聚合物对体外测量的肺表面活性剂功能的影响是剂量率依赖性的。	Sengupta, S.	PDF	N/A	The effect of surfactants and film-forming polymers on pulmonary surfactant function measured in vitro is dose-rate dependent
删除率限制乳腺癌和卵巢癌的启动	Houlahan, K.	PDF	N/A	Deletions Rate-Limit Breast and Ovarian Cancer Initiation
IDH突变型胶质瘤起源于携带初始驱动突变的胶质祖细胞。	Park, J. W.	PDF	N/A	IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation
S100a4阳性肺泡巨噬细胞通过促进脂肪酸代谢加速癌前病变不典型腺瘤样增生的进展	Huang, H.	PDF	N/A	S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting fatty acid metabolism
整合素α1β1在小鼠多囊肾病模型中促进间质纤维化	Grenier, C.	PDF	N/A	Integrin alpha1 beta1 promotes interstitial fibrosis in a mouse model of polycystic kidney disease
性激素和季节变化对褪黑素抑制及光警觉反应的影响	Fazlali, F.	PDF	N/A	Sex and seasonal variations in melatonin suppression, and alerting response to light
在固定期间进行的次最大离心训练并不能防止老年或年轻大鼠的串联肌节丢失或机械功能障碍。	Hinks, A. A.	PDF	N/A	Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats
二维猪结肠类器官模型的开发与特性研究：用于肠道生理学与屏障功能的研究	Plenge, M.	PDF	N/A	Development and Characterization of a 2D Porcine Colonic Organoid Model for Studying Intestinal Physiology and Barrier Function
病毒感染和温度对不同温度耐受性甜瓜和西葫芦植株基因响应的综合影响	de Moya-Ruiz, C.	PDF	N/A	The combined effect of viral infection and temperature on the gene response of melon and zucchini plants with different levels of temperature tolerance
蛋白质分解产物作为基于血液的衰老生理标志物：来自狗衰老项目的发现	Harrison, B. R.	PDF	N/A	Protein catabolites as blood-based biomarkers of aging physiology: Findings from the Dog Aging Project
在癌症的网络基础分层分析中整合基因和基因表达数据	Liou, K.	PDF	N/A	Integrating genetic and gene expression data in network-based stratification analysis of cancers
系统性CGRP和PACAP-38对C57BL/6J小鼠运动诱发恶心和平衡行为的影响：一项比较研究	Rahman, S. M.	PDF	N/A	Systemic CGRP and PACAP-38's Effects on Motion-Induced Nausea and Balance Behaviors in C57BL/6J Mice: A Comparison
使用电影刺激模拟人类社会视觉	Santavirta, S.	PDF	N/A	Modelling human social vision with cinematic stimuli
神经元TDP-43聚集在肌萎缩侧索硬化症中驱动小胶质细胞形态变化，先于免疫表型出现。	Swanson, M. E. V.	PDF	N/A	Neuronal TDP-43 aggregation drives changes in microglial morphology prior to immunophenotype in amyotrophic lateral sclerosis
不公平会引发愤怒还是厌恶？基于25年神经影像学的定量神经功能剖析	Gan, X.	PDF	N/A	Does Unfairness Evoke Anger or Disgust? A Quantitative Neurofunctional Dissection Based on 25 Years of Neuroimaging
hnRNP A2/B1剪接变体的细胞质积累在FUS相关的小鼠ALS模型中促成了毒性作用。	Rossi, S.	PDF	N/A	Cytoplasmic accumulation of a splice variant of hnRNP A2/B1 contributes to FUS-associated toxicity in a mouse model of ALS
非致幻的5-羟色胺1B受体对于裸盖菇素在小鼠中的抗抑郁样效应是必要的。	Fleury, S.	PDF	N/A	The non-hallucinogenic serotonin 1B receptor is necessary for the antidepressant-like effects of psilocybin in mice
人类空间导航过程中前额叶Theta和顶叶Alpha振荡事件的单次试验特征	Cuello, M. T.	PDF	N/A	Single trial characterization of frontal Theta and parietal Alpha oscillatory episodes during Spatial Navigation in humans
一种测量骑行期间动机相关事件相关电位（ERP）指标的方法	Renoud-Grappin, R.	PDF	N/A	A Measure of Event-Related Potentials (ERP) Indices of Motivation During Cycling
一项大规模的非注意盲视实验揭示了身体检测的反转效应	Gandolfo, M.	PDF	N/A	A body detection inversion effect revealed by a large-scale inattentional blindness experiment
在斑马鱼幼体中M电流对初级运动神经元兴奋性控制的发展变化	Gaudreau, S. F.	PDF	N/A	Developmental changes in the control of primary motoneuron excitability by the M-current in larval zebrafish
从卵到内脏：新种Sodalis nezarae sp. nov.与南方绿蝽Nezara viridula的共生关系	Rogowska-van der Molen, M. A.	PDF	N/A	From Eggs to Guts: Symbiotic Association of Sodalis nezarae sp. nov. with the Southern Green Shield Bug Nezara viridula
基础EFNA3通过促进氧化磷酸化（OXPHOS），促进乳腺上皮细胞的管腔驱动迁移和癌症转移	Chen, J.	PDF	N/A	Basal EFNA3 Facilitates Luminal-Driving Mammary Epithelial Migration and Cancer Metastasis by Promoting OXPHOS
寨卡病毒和登革病毒通过不同地调控宿主mRNA加工因子来定义其毒力	Scholl, A.	PDF	N/A	Zika and Dengue Viruses Differentially Modulate Host mRNA Processing Factors Defining Its Virulence
基于模型的紫罗兰植物细胞分批培养表现出抗疟和抗癌活性	R, B.	PDF	N/A	Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity
体内保护效果：大黄素在达尔顿腹水淋巴瘤诱导的瑞士白化小鼠中的保护作用	Suluvoy, J. K.	PDF	N/A	In vivo Protective Efficacy of Emodin in Swiss Albino Mice Induced with Dalton Ascitic Lymphoma
系统性和局部慢性炎症以及激素分布促进了老年女性乳腺癌易感环境的发展。	Carleton, N.	PDF	N/A	Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women
基于形态学和分子证据，华东地区一种新的荚蒾属（忍冬科）植物——荚蒾属新种	Zhao, L.	PDF	N/A	A new synonym for Viburnum erosum (Viburnaceae) in East China, based on morphological and molecular evidence
孟加拉国退化栖息地中濒危的西白眉长臂猿（Hoolock hoolock）的蠕虫寄生虫感染情况	Kabir, M. T.	PDF	N/A	Helminthic parasite infections of endangered western hoolock gibbons (Hoolock hoolock) in degraded habitats of Bangladesh
雄性特异性sNPF肽能神经回路通过神经-胶质相互作用控制能量平衡以调节交配时长。	Zhang, X.	PDF	N/A	Male-specific sNPF peptidergic circuits control energy balance for mating duration through neuron-glia interactions.
在功能性PET（fPET）-FDG的分析中：基线特征的错误描述可能导致代谢（去）激活的伪影。	Coursey, S. E.	PDF	N/A	On the analysis of functional PET (fPET)-FDG: baseline mischaracterization can introduce artifactual metabolic (de)activations
纹状体中持续性和相位性多巴胺释放的宽带比率测量	Gottschalk, A.	PDF	N/A	Wideband ratiometric measurement of tonic and phasic dopamine release in the striatum
吗啡诱导的痛觉过敏影响小细胞外囊泡miRNA组成和功能	Reddy, D.	PDF	N/A	Morphine-induced hyperalgesia impacts small extracellular vesicle miRNA composition and function
在生态学和进化领域，朝着更全面验证基于机器学习的研究方法迈进	Christensen, C.	PDF	N/A	Moving towards more holistic validation of machine learning-based approaches in ecology and evolution
研究3'UTR中CpG岛DNA甲基化在癌症中的作用	Wilson, C.	PDF	N/A	Investigating the role of CpG island DNA methylation at 3'UTRs in cancer
骨盆环骨折：脊柱骨盆对位是否影响骶骨和腰骨盆固定稳定性？	Tripathi, S.	PDF	N/A	Pelvic Ring Fractures: Does Spinopelvic Alignment Affect Sacral and Lumbopelvic Fixation Stability?
DeepVul：一种用于联合预测基因必需性和药物反应的多任务Transformer模型	Jararweh, A.	PDF	N/A	DeepVul: A Multi-Task Transformer Model for Joint Prediction of Gene Essentiality and Drug Response
分子动力学模拟揭示了非天然相互作用在调节孕酮受体从非活性到活性构象转变中的重要性	Hazarika, S.	PDF	N/A	Molecular Dynamics Simulations Reveal the Importance of Non-Native Interactions in Modulating the Inactive to Active Conformational Transition in Progesterone Receptor
ACSS2在乳腺癌脑转移细胞中通过E2F1依赖的方式调控铁死亡	Esquea, E.	PDF	N/A	ACSS2 regulates ferroptosis in an E2F1-dependent manner in breast cancer brain metastatic cells
受体信号放大定量分析：完全激动剂的Kd/EC50比值作为增益参数	Buchwald, P.	PDF	N/A	Quantification of Signal Amplification for Receptors: The Kd/EC50 Ratio of Full Agonists as a Gain Parameter
E3泛素连接酶LIFERING以酰基辅酶A脱氢酶样蛋白IBR3为目标，进行泛素化，并在DNA损伤时协调细胞增殖和细胞死亡。	Kallai, B.	PDF	N/A	LIFERING, an E3 ligase, targets the acyl-CoA dehydrogenase-like protein IBR3, for ubiquitination and coordinates cell proliferation and cell death upon DNA damage
蛋白酶体抑制通过下调HLA-E增强潜伏逆转并提升NK细胞介导的HIV-1感染细胞清除	Laeremans, T.	PDF	N/A	Proteasome inhibition enhances latency reversal and boosts NK cell-mediated elimination of HIV-1 infected cells through HLA-E downregulation
脂肪酸去饱和酶通过连接细胞代谢途径来促进EB病毒感染的B细胞的增殖。	Bonglack, E. N.	PDF	N/A	Fatty acid desaturases link cell metabolism pathways to promote proliferation of Epstein-Barr virus-infected B cells
军团菌科家族的扩展、重构与特征描述	Gabrielli, M.	PDF	N/A	Expansion, restructuring and characterization of the Legionellaceae family
晶体学和核磁共振研究显示，肺炎链球菌LCP蛋白PsrSp中四个长环的动力学对配体特异性具有重要意义。	Sandalova, T.	PDF	N/A	Crystallographic and NMR studies of Streptococcus pneumonia LCP protein PsrSp indicate the importance of dynamics in four long loops for ligand specificity
揭示肠道微生物组网络指纹：一种用于预测黑色素瘤患者免疫治疗反应的深度学习方法。	Sun, J.	PDF	N/A	Unveiling the Gut Microbiome Network Fingerprint: A Deep Learning Approach to Predict Immunotherapy Response in Melanoma Patients.
拟杆菌属和福氏杆菌属原噬菌体多样性、宿主范围及时间稳定性的见解	Hedzet, S.	PDF	N/A	Insights into Diversity, Host-Range, and Temporal Stability of Bacteroides and Phocaeicola Prophages
一种巴斯德氏菌表面的脂蛋白能够结合补体因子I，以促进免疫逃避。	Nguyen, Q. H.	PDF	N/A	A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.
可遗传的种子携带细菌的优先效应推动了小麦根际微生物群的早期构建	Garrido-Sanz, D.	PDF	N/A	Priority effects of heritable seed-borne bacteria drive early assembly of the wheat rhizosphere microbiome
O特异性抗原的丧失塑造了铜绿假单胞菌在小鼠临床前肺部感染模型中的微生物地理分布	Fraser, H.	PDF	N/A	Loss of O-specific antigen shapes Pseudomonas aeruginosa microbiogeography in murine preclinical pulmonary infection model
一种基因组显著缩小的红假单胞菌菌株保留了其属的核心代谢多功能性。	Oda, Y.	PDF	N/A	A Rhodopseudomonas strain with a substantially smaller genome retains the core metabolic versatility of its genus
禽源硝基呋喃妥因耐药大肠杆菌的动物源性传播潜力	Sealey, J.	PDF	N/A	The Zoonotic Potential of Poultry-Associated Nitrofurantoin-Resistant Escherichia coli
苯并异噁唑-4,7-二酮类化合物的药物化学研究揭示了核糖体小亚基作为特定分枝杆菌翻译准确性靶点的潜力。	Wu, J.	PDF	N/A	Medicinal chemistry of benzoisoxazole-4,7-dione analogues identifies the ribosomal small subunit as a target for specific mycobacterial translational fidelity
通过流式细胞术对水生生态系统进行高通量病毒计数	Bellanger, M.	PDF	N/A	High Throughput Viral Enumeration of Aquatic Ecosystems via Flow Cytometry
铜绿假单胞菌通过代谢交叉喂养支持坏疽性拟杆菌在囊性纤维化肺部多菌种群落中的生存。	El Hafi, B.	PDF	N/A	Pseudomonas aeruginosa supports the survival of Prevotella melaninogenica in a cystic fibrosis lung polymicrobial community through metabolic cross-feeding
P3 定点突变：基于带有3'突出端的引物对的高效方法	Mousavi, N.	PDF	N/A	P3 site-directed mutagenesis: An efficient method based on primer pairs with 3-prime overhangs
通过不育昆虫技术（SIT）在佛罗里达州卡皮塔岛对埃及伊蚊的抑制，2020年至2022年	Morreale, R.	PDF	N/A	SUPPRESSION OF AEDES AEGYPTI BY STERILE INSECT TECHNIQUE (SIT) ON CAPTIVA ISLAND, FLORIDA, USA FROM 2020 TO 2022
自然杀伤细胞和单核细胞的综合转录组分析：推进COVID-19的诊断和治疗策略	Loukman, S.	PDF	N/A	Integrative Transcriptomic Profiling of NK Cells and Monocytes: Advancing Diagnostic and Therapeutic Strategies for COVID-19.
这是SPRTA：在疫情规模下评估系统发育置信度	De Maio, N.	PDF	N/A	This is SPRTA: assessing phylogenetic confidence at pandemic scales
工程设计抗逆基因驱动以实现可持续的疟疾控制：预测、测试及克服目标位点抗性	Morianou, I.	PDF	N/A	Engineering Resilient Gene Drives Towards Sustainable Malaria Control: Predicting, Testing and Overcoming Target Site Resistance
除核糖体外，整个蛋白质翻译机器的自发生物发生	Schwarz-Schilling, M.	PDF	N/A	Autonomous biogenesis of the entire protein translation machinery excluding ribosomes
精确连续尖峰率推断	Stern, M.	PDF	N/A	Exact Continuous Spiking Rate Inference
神经和行为的重现共同反映了叙事事件的提取。	Nau, M.	PDF	N/A	Neural and behavioral reinstatement jointly reflect retrieval of narrative events
DprA招募ComM，以促进革兰氏阴性菌在自然转化过程中进行重组	Dalia, T. N.	PDF	N/A	DprA recruits ComM to facilitate recombination during natural transformation in Gram-negative bacteria
开发和利用表达绿色荧光蛋白的梅毒螺旋体以研究螺旋体与宿主的相互作用及抗体介导的清除机制：扩展梅毒研究工具箱。	Delgado, K. N.	PDF	N/A	Development and utilization of Treponema pallidum expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox for syphilis research.
新鉴定的SpoVAF/FigP复合物：在中等高压下枯草芽孢杆菌孢子萌发中的作用及影响因素	Lyu, F.	PDF	N/A	Newly identified SpoVAF/FigP complex: the role in Bacillus subtilis spore germination at moderate high pressure and influencing factors
A群链球菌的甘露糖磷酸转移酶系统（Man-PTS）影响抗菌活性及特定鼻咽感染的生态位。	Marple, A. C.	PDF	N/A	The Streptococcus pyogenes mannose phosphotransferase system (Man-PTS) influences antimicrobial activity and niche-specific nasopharyngeal infection
一种用于体外发现和体内测试恶性疟原虫疟疾传播阻断药物的一体化流程	Brancucci, N. M. B.	PDF	N/A	An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs
基于单细胞转录组学和多重抗体成像的人类精子发生时空图谱	Hikmet, F.	PDF	N/A	A spatiotemporal atlas of human spermatogenesis based on single-cell transcriptomics and multiplex antibody imaging
禾谷镰刀菌铜胺氧化酶通过将植物防御化合物水解产生的色胺转化为生长素，从而冗余地增加致病性。	Svoboda, T.	PDF	N/A	Fusarium graminearum copper amine-oxidases redundantly increase virulence by converting tryptamine from hydrolyzed plant defense compounds into auxin
走向一个统一的尾噬菌体系统发育框架	Weinheimer, A. R.	PDF	N/A	Towards a unifying phylogenomic framework for tailed phages
使用AlphaFold深入探究Polo样激酶活性的结构调控	Wyatt, M. D.	PDF	N/A	Insights into the Structural Regulation of Polo-Like Kinase Activity using AlphaFold
工程化的Bxb1变体提高了整合酶活性和保真度	Rose, J.	PDF	N/A	Engineered Bxb1 variants improve integrase activity and fidelity
TALE蛋白的计算重设计用于DNA模板化的蛋白质纤维组装	de Haas, R. J.	PDF	N/A	Computational redesign of TALE proteins for DNA-templated assembly of protein fibers
合成生物学中的多功能系统：利用单链DNA信号实现基因激活的精准控制	Ng, B.	PDF	N/A	Multifunctional Systems in Synthetic Biology: Single-Stranded DNA Signaling for Precise Control of Gene Activation
基于显著性的刺激选择在鸟类中脑峡部大细胞部中的叠加抑制性环绕机制	Qian, L.	PDF	N/A	Superimposed inhibitory surrounds underlying Saliency-based Stimulus Selection in avian Midbrain isthmi pars magnocellularis
通过Type V CRISPR-Cas12a系统设计的人类线粒体DNA定向缺失	Nikitchina, N.	PDF	N/A	Targeted deletions in human mitochondrial DNA engineered by Type V CRISPR-Cas12a system
扩展采样方法用于巨冠蝾螈（Triturus cristatus）的环境DNA监测	Harper, L. R.	PDF	N/A	Extending sampling approaches for great crested newt (Triturus cristatus) eDNA monitoring
可持续农业实践的生态和经济效益：来自大面积谷物作物农场试验的证据	Mata, L.	PDF	N/A	The ecological and economic benefits of sustainable agricultural practices: Evidence from on-farm trials in broad-acre grain crops
极地浮游宿主中藻类质体和线粒体的劫持与整合	Rao, A. K.	PDF	N/A	Hijacking and Integration of Algal Plastids andMitochondria in a Polar Planktonic Host
在加拿大萨斯卡通市，从城市到乡村的梯度上，草原驼鹿的空间和时间分布情况	Harris, K. E.	PDF	N/A	Spatial and temporal occurrences of prairie moose across an urban to rural gradient in Saskatoon, Canada
载脂蛋白A-IV多态性Q360H和T347S的结构分析阐明了其抗血栓形成的作用机制	Shoara, A. A.	PDF	N/A	Structural analyses of apolipoprotein A-IV polymorphisms Q360H and T347S elucidate the inhibitory effect against thrombosis
通过神经递质转运蛋白4（NTT4，SLC6A17）转运谷氨酰胺在中枢神经系统兴奋性突触处维持突触前谷氨酸供应	Nicoli, A. L.	PDF	N/A	Glutamine Transport via Neurotransmitter Transporter 4 (NTT4, SLC6A17) Maintains Presynaptic Glutamate Supply at Excitatory Synapses in the Central Nervous System
解聚F-肌动蛋白可加速多能性退出，从而增强干细胞衍生的胰岛分化	Hogrebe, N. J.	PDF	N/A	Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation
集群组装动力学驱动平面细胞极性极化的保真度	Nissen, S. B.	PDF	N/A	Cluster Assembly Dynamics Drive Fidelity of Planar Cell Polarity Polarization
# BioRxiv 2024-10-20 Papers

标题	作者	PDF链接	代码仓库	Title
肺炎球菌生物合成基因突变体保留上皮微侵袭并诱导先天免疫	Weight, C. M.	PDF	N/A	Pneumococcal biosynthesis gene mutants retain epithelial microinvasion and induce innate immunity
宏观进化最优突变率的证据	Irlam, G.	PDF	N/A	Evidence for the macroevolutionarily optimal mutation rate
能否利用模型从动作信号中推断出关于僵硬感知的信息？	Kossowsky Lev, H.	PDF	N/A	Can Information About Stiffness Perception be Inferred from Action Signals Using Models?
季节性迁徙的鸣禽与其留鸟亲属相比，具有不同的历史种群规模特征。	Winker, K.	PDF	N/A	Seasonally migratory songbirds have different historic population size characteristics than resident relatives.
蛋白质-DNA簇解释了转录因子非指数DNA停留时间分布	Kosar, Z.	PDF	N/A	Protein-DNA Clusters Explain the Non-ExponentialDNA Residence Time Distributions of TranscriptionFactors
非靶向蛋白质组学鉴定出细菌来源的ADP-核糖基转移酶AvrRpm1的植物底物	Kaur, S.	PDF	N/A	Untargeted proteomics identifies plant substrates of the bacterial-derived ADP-ribosyltransferase AvrRpm1
聚类内分析揭示了组织特异性的突变模式	Choudalakis, S.	PDF	N/A	Intra-clustering analysis reveals tissue-specific mutational patterns
记忆元认知成分由楔前叶与海马间高伽马活动结构性地支持	Pan, K.	PDF	N/A	Components of Mnemonic Metacognition Constitutionally Supported by High Gamma Activity Between the Precuneus and Hippocampus
利用nMOST技术对多种溶酶体贮积病突变体进行全球细胞蛋白质脂质组学分析	Kraus, F.	PDF	N/A	Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST
对豆类壳二孢菌进行群体水平的基因组测序，鉴定出与菌株毒力相关的基因组位点	Vaghefi, N.	PDF	N/A	Population-level whole genome sequencing of Ascochyta rabiei identifies genomic loci associated with isolate aggressiveness
大脑皮层对说话者频谱变化的追踪预测了选择性听觉	Cervantes Constantino, F.	PDF	N/A	Cortical tracking of speakers' spectral changes predicts selective listening
使用诱捕法评估串联质谱分析中假发现率的控制	Wen, B.	PDF	N/A	Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment
加速度传感与PIDA控制的生化实现	Alexis, E.	PDF	N/A	Biochemical implementation of acceleration sensing and PIDA control
生化实现加速度传感与PIDA控制（扩展版）	Alexis, E.	PDF	N/A	Biochemical implementation of acceleration sensing and PIDA control (Extended Version)
突触蛋白的凝聚受到序列编码的分子语法调控。	Hoffmann, C.	PDF	N/A	Synapsin condensation is governed by sequence-encoded molecular grammars
音乐性增强选择性注意：从同时神经反应的精确分离中获得的时空洞察	Manting, C. L.	PDF	N/A	Musicality enhances selective attention: spatiotemporal insights from precise separation of simultaneous neural responses
GCK-MODY中独特的持续时间和饮食依赖性脂质谱及肾脏并发症	Huang, Y.	PDF	N/A	Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
在破伤风毒素癫痫模型中减少突触异质性：来自计算建模的见解	Zarei Eskikand, P.	PDF	N/A	Reduced Synaptic Heterogeneity in a Tetanus ToxinModel of Epilepsy: Insights from ComputationalModeling
具有tau病理特征的特发性震颤与阿尔茨海默病和原发性年龄相关性tau病变的种子在构象上无法区分。	Saez-Calveras, N.	PDF	N/A	Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy
破伤风毒素癫痫大鼠模型中的动态多日癫痫发作周期：演变的节律及其对预测的影响	Zarei Eskikand, P.	PDF	N/A	Dynamic Multiday Seizure Cycles in a Tetanus Toxin Rat Model of Epilepsy: Evolving Rhythms and Implications for Prediction
BBATProt：一种通过可解释深度学习增强特征提取的生物功能预测框架	Wang, Y.	PDF	N/A	BBATProt: A Framework Predicting Biological Function with Enhanced Feature Extraction via Explainable Deep Learning
一种分布于植物共生细菌中的排出泵家族，能够调节宿主特异性硫代葡萄糖苷在宿主和器官特异性解毒过程中的作用。	Russ, D.	PDF	N/A	An efflux pump family distributed across plant commensal bacteria conditions host- and organ-specific detoxification of a host-specific glucosinolate
分布于植物共生细菌中的一个排出泵家族，能够调节宿主特异性硫代葡萄糖苷在宿主和器官特异性解毒作用。	Russ, D.	PDF	N/A	An efflux pump family distributed across plant commensal bacteria conditions host- and organ-specific detoxification of a host-specific glucosinolate
CRISPR相关酶在由iPSC衍生的神经元中错误定位到细胞质，导致KRAB特异性降解。	Cajka, G.	PDF	N/A	CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation
额顶叶θ同步化在因果关系上将工作记忆与冲动决策联系起来。	Kapetaniou, G. E.	PDF	N/A	Frontoparietal theta synchronization causally links working memory with impulsive decision making
在脆性X综合征大鼠模型中，海马位置细胞序列受损。	Donahue, M. M.	PDF	N/A	Hippocampal place cell sequences are impaired in a rat model of Fragile X Syndrome
青少年小鼠的慢性昼夜节律紊乱会损害海马体记忆，干扰基因表达的振荡。	Gallego-Landin, I.	PDF	N/A	Chronic circadian disruption in adolescent mice impairs hippocampal memory disrupting gene expression oscillations
新发现的水生甲基杆菌A1菌株降解聚酯聚氨酯的特性研究	Lee, S.	PDF	N/A	Characterization of Newly Discovered Polyester Polyurethane-degrading Methylobacterium Aquaticum Strain A1
体外艰难梭菌野生菌株生物膜：根据菌株多样性的形态和特性	LEMAIRE, A.	PDF	N/A	In vitro biofilms of Clostridioides difficile undomesticated strains: Morphology and properties according to strain diversity
针对铜绿假单胞菌III型分泌系统的保护性人源单克隆抗体可抑制转位子功能。	Desveaux, J.-M.	PDF	N/A	Protective human monoclonal antibodies that target the Type III Secretion System of Pseudomonas aeruginosa inhibit translocon function
N-MYC转录激活域与TFIIIC5 DNA结合表面相互作用的机制	Leen, E.	PDF	N/A	Mechanism of Interaction Between the Transactivation Domain of N-MYC and the DNA-Binding Surface of TFIIIC5
形态特异性选择压力驱动一种颜色多态鸟类表型分化	Passarotto, A.	PDF	N/A	Morph-specific selection pressures drive phenotypic divergence in a color polymorphic bird
揭示混合模型中最大似然估计的范围。	Heinzel, C. S.	PDF	N/A	Revealing the range of maximum likelihood estimates in the admixture model.
冷冻电镜揭示了一种单域抗体，其具有独特的结合表位，位于成纤维细胞激活蛋白α上。	Xu, Z.	PDF	N/A	Cryo-electron microscopy reveals a single domain antibody with a unique binding epitope on fibroblast activation protein alpha
建立和表征一种用于培养肉的非贴壁昆虫细胞系	Letcher, S. M.	PDF	N/A	Establishment & Characterization of a Non-Adherent Insect Cell Line for Cultivated Meat
使用PyProteinInference进行联合蛋白质推断分析，有助于阐明串联质谱数据背后的生物学理解。	Hinkle, T. B.	PDF	N/A	Joint Protein Inference Analysis with PyProteinInference Elucidates Biological Understanding of Tandem Mass Spectrometry Data
苯甲脒介导的人溶菌酶聚集抑制：同源蛋白质中的差异配体结合	Vijayan, D. K.	PDF	N/A	Benzamidine-Mediated Inhibition of Human Lysozyme Aggregation: Differential Ligand Binding in Homologous Proteins
甘蔗黄叶病毒损害了甘蔗对新蚜虫媒介Melanaphis sorghi的转录组防御反应	Pimenta, R. J. G.	PDF	N/A	Sugarcane yellow leaf virus impairs the transcriptomic defense responses of sugarcane to its new aphid vector Melanaphis sorghi
模板驱动的动态功能网络连接预测药物治疗反应用于重度抑郁症和双相情感障碍	Baker, B.	PDF	N/A	Template-driven dynamic functional network connectivity predicts medication response for major depression and bipolar disorders
小胶质细胞通过IGF1调节胎儿人脑中的GABA能神经发生	Yu, D.	PDF	N/A	Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1
半自动化监测纵向微生物代谢动力学：木质素降解研究案例	Guimaraes Ferreira, J. V.	PDF	N/A	Semi-automated monitoring of longitudinal microbial metabolic dynamics: A study case for lignin degradation
富集精原干细胞并确定袋鼬科有袋类动物——肥尾细尾獴的睾丸周期阶段	Tarulli, G. A.	PDF	N/A	Enrichment of spermatogonial stem cells and staging of the testis cycle in a dasyurid marsupial, the fat-tailed dunnart
骨骼肌代谢分析揭示了在秀丽隐杆线虫中延长寿命和健康寿命的正向调节因子	Jonk, S.	PDF	N/A	Metabolic analysis of sarcopenic muscle identifies positive modulators of longevity and health span in C. elegans
利用数据高效且可解释的钾离子和氯离子传导光敏感蛋白模型对CA1神经元光遗传抑制的计算分析	Weyn, L.	PDF	N/A	Computational analysis of optogenetic inhibition of CA1 neurons using a data-efficient and interpretable potassium and chloride conducting opsin model
生物医学大数据操作系统（Bio-OS）：一个集成化的数据密集型科学研究数据挖掘环境	Liu, J.	PDF	N/A	Bio-medical Big Data Operating System (Bio-OS): An Integrated Data Mining Environment for Data Intensive Scientific Research
拟鲤鱼大胆-害羞行为的测量与分类	Pierotti, S.	PDF	N/A	Measurement and classification of bold-shy behaviours in medaka fish
利用生成式人工智能在计算机中生成合成癌症基因组	Diaz-Navarro, A.	PDF	N/A	In silico generation of synthetic cancer genomes using generative AI
全球蛋白质磷酸化反应的比较结构分析	Correa Marrero, M.	PDF	N/A	Global comparative structural analysis of responses to protein phosphorylation
ENACT：Visium高清（HD）数据的端到端分析	Kamel, M.	PDF	N/A	ENACT: End-to-End Analysis of Visium High Definition (HD) Data
评估Pythium oligandrum和Serratia proteamaculans在控制欧洲山毛榉（Fagus sylvatica）中Phytophthora plurivora的生物防治潜力	Kelbessa, B. G.	PDF	N/A	Evaluating the Biocontrol Potential of Pythium oligandrum and Serratia proteamaculans in Controlling Phytophthora plurivora in European beech (Fagus sylvatica)
新加坡九种常见树种光合作用温度依赖性的变异	Teo, L. M. R.	PDF	N/A	Variations in the temperature dependence of photosynthesis among nine common tree species planted in Singapore
基于网络的研究：阿尔茨海默病中Aβ和{tau}蛋白的动力学	Bianchi, S.	PDF	N/A	A network based study of the dynamics of Aβ and {tau} proteins in Alzheimer's disease
衰老大脑中蛋白酶体组成的改变，遗传性蛋白酶体增强减轻了与年龄相关的认知衰退，以及急性蛋白酶体激动剂治疗挽救了小鼠的年龄相关认知缺陷。	Pickering, A.	PDF	N/A	Altered Proteasome Composition in Aging Brains, Genetic Proteasome Augmentation Mitigates Age-Related Cognitive Declines, and Acute Proteasome Agonist Treatment Rescues Age-Related Cognitive Deficits in Mice
雄激素受体对Alston鸣鼠发声回路的调节	Zheng, D.-J.	PDF	N/A	Androgen receptor modulation of vocal circuitry in Alston's singing mouse
达尔文的本土化难题：环境压力和干扰梯度解释	Galman, A.	PDF	N/A	Darwin's Naturalization Conundrum explained by gradients of environmental stress and disturbance
将目标捕获与全基因组测序相结合，对近期和自然历史收藏的样本进行分析，以解释野生和栽培大麻的系统地理学	Balant, M.	PDF	N/A	Integrating target capture with whole genome sequencing of recent and natural history collections to explain the phylogeography of wild-growing and cultivated Cannabis
sv-channels：使用一维卷积神经网络过滤基因组缺失	Santuari, L.	PDF	N/A	sv-channels: filtering genomic deletions using one-dimensional convolutional neural networks
脂肪组织中的PFKFB3蛋白有助于维持全身血糖稳态。	OLSON, A. L.	PDF	N/A	PFKFB3 protein in adipose tissue contributes to whole body glucose homeostasis
inTRACKtive - 一个基于网络的工具，用于交互式细胞追踪可视化	Huijben, T. A. P. M.	PDF	N/A	inTRACKtive - A Web-Based Tool for Interactive Cell Tracking Visualization
deadtrees.earth - 一个开放访问且互动的数据库，用于厘米级航拍影像，揭示全球树木死亡动态	Mosig, C.	PDF	N/A	deadtrees.earth - An Open-Access and Interactive Database for Centimeter-Scale Aerial Imagery to Uncover Global Tree Mortality Dynamics
deadtrees.earth - 一个开放访问和互动的数据库，用于厘米级航拍影像，揭示全球树木死亡动态	Mosig, C.	PDF	N/A	deadtrees.earth - An Open-Access and Interactive Database for Centimeter-Scale Aerial Imagery to Uncover Global Tree Mortality Dynamics
水稻田扁莎Cyperus iria的染色体水平参考基因组和微小RNA	Tsang, S. K.	PDF	N/A	Chromosomal-level reference genome and microRNAs of the ricefield flatsedge Cyperus iria
用于区分心智游移和专注注意的非线性脑电图分析：一种机器学习方法	Sundaram, S.	PDF	N/A	Nonlinear EEG Analysis for Distinguishing Mind Wandering and Focused Attention: A Machine Learning Approach
数据异质性对临床MALDI-TOF质谱图谱通过机器学习进行直接抗菌药物耐药性预测的影响	Park, Y.	PDF	N/A	Effect of Data Heterogeneity in Clinical MALDI-TOF Mass Spectra Profiles on Direct Antimicrobial Resistance Prediction through Machine Learning
中风会损害在可预测跑步机加速过程中对动态平衡的主动控制	Cornwell, T. I.	PDF	N/A	Stroke impairs the proactive control of dynamic balance during predictable treadmill accelerations
通过冷冻电镜断层成像技术可视化的AMPA受体支架复合物的原位结构和形貌	Held, R. G.	PDF	N/A	In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET
MEGF10在肌细胞融合和骨骼肌超负荷肥大反应中的作用	Richardson, L.	PDF	N/A	The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscle
稳定性与灵活性：在计算机模拟中重塑单层和双层古菌膜	Amaral, M.	PDF	N/A	Stability vs flexibility: reshaping monolayer and bilayer archaeal membranes in silico
功能和泛基因组探索Roc双组分调控系统在假单胞菌属中的新角色	SIMON, V.	PDF	N/A	Functional and pangenomic exploration of Roc two-component regulatory systems identifies novel players across Pseudomonas species
精神分裂症风险基因SETD1A的突变会扰乱人类神经元中的突触功能	Su, X.	PDF	N/A	Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons
封闭杏仁核和古皮质神经元的分子特征及其连接性	Kaur, N.	PDF	N/A	Molecular Specification of Claustro-Amygdalar and Paleocortical Neurons and Connectivity
# BioRxiv 2024-10-19 Papers

标题	作者	PDF链接	代码仓库	Title
通过测量神经活动进行效用的个体间比较	Matsumori, K.	PDF	N/A	Interpersonal Comparison of Utility by Measuring Neural Activity
RatXcan：一种用于跨物种整合全基因组关联和基因表达数据的框架	Santhanam, N.	PDF	N/A	RatXcan: A framework for cross-species integration of genome-wide association and gene expression data
生活方式塑造了真菌病原体的基因组大小和基因含量	Fijarczyk, A.	PDF	N/A	Lifestyles shape genome size and gene content in fungal pathogens
鸣禽发声模仿的传感器运动回路的突触连接	Trusel, M.	PDF	N/A	Synaptic Connectivity of Sensorimotor Circuits for Vocal Imitation in the Songbird
拟南芥根尖（V2）中tRNASer/tRNATyr基因簇的转录再激活	Hummel, G.	PDF	N/A	Transcriptional reactivation of the tRNASer/tRNATyr gene cluster in Arabidopsis thaliana root tip (V2)
分子伴侣的局部合成维持了神经元的蛋白质稳态	Alecki, C.	PDF	N/A	Localized synthesis of molecular chaperones sustains neuronal proteostasis
在人类类器官中以细胞类型为重点的化合物筛选揭示了CK1和MAPK11的抑制保护视锥光感受器免于死亡	Spirig, S. E.	PDF	N/A	Cell type-focused compound screen in human organoids reveals CK1 and MAPK11 inhibition protects cone photoreceptors from death
光纤光度实验中试验级时间动态分析的统计框架	Loewinger, G.	PDF	N/A	A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments
分层运动感知作为因果推断	Shivkumar, S.	PDF	N/A	Hierarchical motion perception as causal inference
衰老过程中细胞外基质的重塑与突触、小胶质细胞及认知状态相一致	Gray, D. T.	PDF	N/A	Extracellular matrix remodeling during aging aligns with synapse, microglia, and cognitive status
对皮层内和皮层-丘脑模型中的阿尔法节律进行了全面调查	Bastiaens, S. P.	PDF	N/A	A comprehensive investigation of intracortical and corticothalamic models of alpha rhythms
RNAinformer：结合三级相互作用的生成性RNA设计	Patil, S.	PDF	N/A	RNAinformer: Generative RNA Design With Tertiary Interactions
慢性乙醇暴露会导致纹状体中认知灵活性和决策信号的持续损伤	Cheng, Y.	PDF	N/A	Chronic Ethanol Exposure Produces Persistent Impairment in Cognitive Flexibility and Decision Signals in the Striatum
基底神经节输出 - 内顶核 - 自由活动小鼠中对情境运动学和奖励的编码	Verma-Rodriguez, A. K.	PDF	N/A	Basal ganglia output - entopeduncular nucleus - coding of contextual kinematics and reward in the freely moving mouse
发展性语言障碍（DLD）儿童对节奏性言语的神经处理：一项脑电图研究	Keshavarzi, M.	PDF	N/A	Neural processing of rhythmic speech by children with developmental language disorder (DLD): An EEG study
通过全基因组测序揭示巴基斯坦山羊中斯氏毛圆线虫的群体遗传学	Afshan, K.	PDF	N/A	The population genetics of Strongyloides papillosus in Pakistani goats revealed by whole genome sequencing
豌豆（Pisum sativum）在根瘤层面会对效果较差的菌株实施限制，但不会在混合根瘤中进行。	Underwood, T. J.	PDF	N/A	Pisum sativum applies sanctions to less effective strains at the nodule level, but not within mixed nodules
利用功能磁共振成像任务对人类听觉和视觉丘脑进行功能定位	Williams, J. C.	PDF	N/A	Functional Localization of the Human Auditory and Visual Thalamus Using a Thalamic Localizer Functional Magnetic Resonance Imaging Task
利用历史偶然进展选择基因进行分析：从RNA变化到蛋白质相互作用	Lalit, F.	PDF	N/A	Selecting genes for analysis using historically contingent progress: from RNA changes to protein-protein interactions
钙调蛋白/C16orf74中的一种新基序决定了通过钙调神经磷酸酶进行的聚合脱磷酸化	Bradburn, D. A.	PDF	N/A	A novel motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin
使用诱捕法评估串联质谱分析中的假发现率控制	Wen, B.	PDF	N/A	Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment
通过水平转移，pMAB625质粒编码的MMPL家族转运蛋白在全球范围内传播于耐多药的脓肿分枝杆菌临床分离株中。	Ohse, K.	PDF	N/A	Worldwide spreading of pMAB625 plasmid encoding MMPL family transporter in multidrug-resistant clinical isolates of Mycobacterium abscessus by horizontal transfer
口服万古霉素治疗改变了吲哚衍生物和次级胆酸的水平，这些变化调节了在实验性自身免疫性脑脊髓炎（EAE）期间星形胶质细胞中mTOR通路基因的表达。	Bianchimano, P.	PDF	N/A	Oral vancomycin treatment alters levels of indole derivatives and secondary bile acids modulating the expression of mTOR pathway genes in astrocytes during EAE
迈向更客观且高通量的球体侵袭实验定量方法	Mungai, R. W.	PDF	N/A	Towards a More Objective and High-throughput Spheroid Invasion Assay Quantification Method
一种用于皮质抑制时间多样性的树突状基质	Morabito, A.	PDF	N/A	A dendritic substrate for temporal diversity of cortical inhibition
果蝇幼虫和成虫中枢神经系统中iPLA2-VIA基因表达的分析	Moura, G.	PDF	N/A	Analysis of iPLA2-VIA Gene Expression in The CNS of Larvae and Adult Drosophila Melanogaster Flies
评估高致病性禽流感H5病毒在法国肉鸡和蛋鸡生产网络中传播的风险	Hautefeuille, C.	PDF	N/A	Assessing the risk of highly pathogenic avian influenza H5 viruses spread within French broiler and layer production networks
一个依赖于气候和人口的扩散模型预测了白纹伊蚊在欧洲的传播情况。	Barman, S.	PDF	N/A	A climate and population dependent diffusion model forecasts the spread of Aedes Albopictus mosquitoes in Europe
在广泛共识的基础上，开发并详细测序了一对匹配的肿瘤-正常基因组瓶对。	McDaniel, J. H.	PDF	N/A	Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair
插入偏倚对piRNA簇的影响及其对转座元件入侵的影响	Pritam, S.	PDF	N/A	The impact of insertion bias into piRNA clusters on the invasion of transposable elements
已发表的兔核糖体rRNA序列中的不一致性：关于序列和位点编号统一性的建议	De, S.	PDF	N/A	Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering
结构和功能证据支持将小鼠的高级视觉区域重新定义为单一的V2区域。	Rowley, D. P.	PDF	N/A	Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2
孢粉素生物合成中的聚酮途径是陆地植物（胚胎植物门）所特有的。	Sraan, D. K.	PDF	N/A	The polyketide pathway in sporopollenin biosynthesis is specific to land plants (Embryophyta)
大多数L1CAM并不与人类生物液体和诱导多能干细胞衍生的神经元中的细胞外囊泡相关联。	Kadam, V.	PDF	N/A	Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC-derived neurons
多样化的祖先揭示了真核起源期间复杂的共生相互作用	Bernabeu, M.	PDF	N/A	Diverse ancestries reveal complex symbiotic interactions during eukaryogenesis
自闭症中白质微观结构改变的局部化与束分析	Kim, G. S.	PDF	N/A	White Matter Microstructural Alterations in Autism Localized with Bundle Analytics
脆性X综合征的iPSC模型反映了临床表型，并揭示了m6A介导的表观转录组失调，这种失调是突触功能障碍的基础。	Guo, Z.	PDF	N/A	An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m6A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction
联邦深度学习通过蛋白质组学实现癌症亚型分类	Cai, Z.	PDF	N/A	Federated deep learning enables cancer subtyping by proteomics
艺术的隐藏拓扑结构：窥探人类感知的一扇窗	Dmitruk, E.	PDF	N/A	Art's Hidden Topology: A window into human perception
艺术中的隐藏拓扑结构：窥探人类感知的一扇窗	Dmitruk, E.	PDF	N/A	Art's Hidden Topology: A window into human perception
基于代理的拟南芥合子中皮质微管带运动的模拟	Nonoyama, T.	PDF	N/A	Agent-Based Simulation of Cortical Microtubule Band Movement in the Arabidopsis Zygote
Spectrin协调皮质肌动肌球蛋白的组织和分化，这对功能性上皮屏障至关重要。	Soffer, A.	PDF	N/A	Spectrin coordinates cortical actomyosin organization and differentiation essential for a functional epithelial barrier
揭示隐藏威胁：通过DNA条形码技术探索毛里塔尼亚班克·阿尔金国家公园（PNBA）中的海洋无脊椎动物入侵	Moura, C. J.	PDF	N/A	Revealing Hidden Threats: Marine Invertebrate Invasions in the Banc d'Arguin National Park (PNBA), Mauritania, Explored Through DNA Barcoding
人类和非人类灵长类动物杏仁核亚区转录组多样性	Totty, M. S.	PDF	N/A	Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates
在大规模外排敲除系统中确定铜绿假单胞菌MexXY-OprM特异性揭示了不同的抗生素底物类别	Kavanaugh, L. G.	PDF	N/A	Determination of Pseudomonas aeruginosa MexXY-OprM specificity in a major efflux knockout system reveals distinct antibiotic substrate classes
在大规模排出敲除系统中确定铜绿假单胞菌MexXY-OprM特异性揭示了不同的抗生素底物类别	Kavanaugh, L. G.	PDF	N/A	Determination of Pseudomonas aeruginosa MexXY-OprM specificity in a major efflux knockout system reveals distinct antibiotic substrate classes
转谷氨酰胺酶2依赖的H3K4me3的丝氨酰化对RIPK3的表观遗传调控影响坏死性凋亡	Vecchio, A.	PDF	N/A	Epigenetic modulation of RIPK3 by Transglutaminase 2-dependent serotonylation of H3K4me3 affects necroptosis
人类参考iPSC系KOLF2.1J的光学基因组图谱揭示了神经发育基因中的新型较小结构变异	Yang, M. J.	PDF	N/A	Optical Genome Mapping of the human reference iPSC line KOLF2.1J reveals new smaller structural variants in neurodevelopmental genes
人类谱系的深层合并历史	Cousins, T.	PDF	N/A	Deep coalescent history of the hominin lineage
无需全基因组测序即可确定肿瘤中人乳头瘤病毒整合的新型纳米孔测序方法	Parida, P.	PDF	N/A	Novel nanopore sequencing method for determining Human Papillomavirus integrations in tumors without the need for whole genome sequencing
剖析由串联RNA结合结构域介导的RNA选择性	Harris, S. E.	PDF	N/A	Dissecting RNA Selectivity Mediated by Tandem RNA-Binding Domains
通过高通量蛋白质组学实现对脑蛋白新底物景观的无偏映射	Rankovic, Z.	PDF	N/A	Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics
利用SPARCE技术对低细胞数量进行多重磷酸蛋白质组学分析	Gaizley, E. J.	PDF	N/A	Multiplexed phosphoproteomics of low cell numbers using SPARCE
PINK1介导的泛素磷酸化水平升高有助于蛋白酶体功能障碍，并促进神经退行性变。	Chen, C.	PDF	N/A	Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration
CelFDrive：人工智能辅助显微镜技术，用于稀有事件的自动化检测	Brooks, S.	PDF	N/A	CelFDrive: Artificial Intelligence assisted microscopy for automated detection of rare events
系统性锕-225阿尔法粒子树状放射偶联物治疗胶质母细胞瘤的效果通过化疗得到改善	Nair, R. R.	PDF	N/A	Glioblastoma Treatment by Systemic Actinium-225 alpha-particle Dendrimer-radioconjugates is Improved by Chemotherapy
感染卡波西肉瘤相关疱疹病毒的内皮细胞显示出独特的黏弹性和形态特征。	Shabangu, M. M.	PDF	N/A	Endothelial cells infected with Kaposi's sarcoma-associated herpesvirus display distinct viscoelasticity and morphology
牙买加果蝠（Artibeus jamaicensis）对埃博拉病毒而非马尔堡病毒的易感性，是由病毒进入宿主细胞和干扰素I型信号通路拮抗作用的内源性差异所驱动的。	Van Tol, S.	PDF	N/A	Jamaican fruit bats (Artibeus jamaicensis) competence for Ebola virus but not Marburg virus is driven by intrinsic differences in viral entry and IFN-I signaling antagonism.
暂停的聚合酶与转录因子及RNA协同作用，增强启动子的转录潜力	Mann, R.	PDF	N/A	Paused Polymerase synergises with transcription factors and RNA to enhance the transcriptional potential of promoters
Setdb1通过抑制允许性染色质结构和转录变异性，调控成年肠道干细胞的正常分化。	Talianidis, I.	PDF	N/A	Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability
TRIM24通过染色质信号传导指导复制应激反应，以维持ALT端粒	Kim, D.	PDF	N/A	TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling
电趋化作用破坏了体外培养的人角膜上皮细胞的细胞间相互作用模式	Crossley, R. M.	PDF	N/A	Electrotaxis disrupts patterns of cell-cell interactions of human corneal epithelial cells in vitro
监测溶酶体降解：评估细胞外蛋白靶向溶酶体降解的敏感探针	Holly, R. W.	PDF	N/A	Monitoring lysosomal catabolism: a sensitive probe for assessing targeted lysosomal degradation of extracellular proteins
Wnt 特异性诱导 FZD5/8 的内吞和降解，并涉及 RSPO-ZNRF3/RNF43 和 DVL 的作用。	Luo, D.	PDF	N/A	Wnt specifically induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL
SNAI2与MEK1/2和HDACs合作，抑制TERT启动子突变癌症中依赖BIM和BMF的凋亡。	Tandon, A.	PDF	N/A	SNAI2 cooperates with MEK1/2 and HDACs to suppress BIM- and BMF-dependent apoptosis in TERT promoter mutant cancers
下丘脑电路机制对压力影响记忆和睡眠的作用	Wiest, A.	PDF	N/A	A hypothalamic circuit mechanism underlying the impact of stress on memory and sleep
人类牙髓干细胞向具有电生理活性的神经样细胞的功能性分化	Pardo-Rodriguez, B.	PDF	N/A	Functional differentiation of Human Dental Pulp Stem Cells into neuron-like cells exhibiting electrophysiological activity
TORC2调控的固醇类物质再分布介导了由小分子两亲性物质引起的膜扰动后的恢复过程。	Tettamanti, M. G.	PDF	N/A	TORC2-regulated sterol redistribution mediates recovery from membrane perturbation by small amphipathic molecules.
IVF患者和卵子捐赠者的生殖道微生物群：一项比较分析	Haahr, T.	PDF	N/A	The genital tract microbiota of IVF patients and oocyte donors: a comparative analysis
对肺炎链球菌细胞壁中磷壁酸的新评估	Mai, N.	PDF	N/A	New assessment of teichoic acids in the cell envelope of Streptococcus pneumoniae
Bicra/Gltscr1的缺失导致小鼠胎儿肝脏中负责红细胞成熟的巨噬细胞功能缺陷。	Sood, S.	PDF	N/A	Loss of Bicra/Gltscr1 leads to a defect in fetal liver macrophages responsible for erythrocyte maturation in mice.
Zebrahub-Multiome：揭示斑马鱼胚胎发育过程中基因调控网络的动态变化	Kim, Y. J.	PDF	N/A	Zebrahub-Multiome: Uncovering Gene Regulatory Network Dynamics During Zebrafish Embryogenesis
拟南芥花药中生殖细胞的机械调控	Liu, C.	PDF	N/A	Mechanical control of germ cell specification in Arabidopsis anthers
Shh信号在再生中的X. tropicalis脊髓中指导背腹分化	Angell Swearer, A.	PDF	N/A	Shh signaling directs dorsal ventral patterning in the regenerating X. tropicalis spinal cord
景天科伽蓝菜属（Kalanchoe）的新系统发育框架及其对属下分类的启示	Rodewald, S. E.	PDF	N/A	A new phylogenetic framework for the genus Kalanchoe (Crassulaceae) and implications for infrageneric classification
在脂质生成型三阴性乳腺癌细胞中，四环素转录激活受到破坏。	Townsel, A.	PDF	N/A	Tet Transgene Activation is Disrupted in Lipogenic Triple Negative Breast Cancer Cells
通过分离相分离调控合成细胞内的生物冷凝物	Chen, C.	PDF	N/A	Regulating biocondensates within synthetic cells via segregative phase separation
SARS-CoV-2 Mpro中的奈玛特韦耐药突变通过切割NF-κB必需调节因子增强宿主免疫逃避	Thomas, M.	PDF	N/A	Nirmatrelvir-Resistant Mutations in SARS-CoV-2 Mpro Enhance Host Immune Evasion via Cleavage of NF-κB Essential Modulator
叶菜类蔬菜的栽培条件决定了叶际细菌群落结构，并最终影响李斯特菌在采后阶段的生长。	Culliney, P.	PDF	N/A	Cultivation conditions of leafy vegetables determine phyllosphere bacterial community structures and ultimately affect growth of L. monocytogenes post-harvest
识别并减轻血液对AgNbO3颗粒抗菌活性的干扰	Talebpour, C.	PDF	N/A	Identification and mitigation of blood's interference with the antimicrobial activity of AgNbO3 particles
发现广谱细菌多胺解毒抑制剂作为潜在的抗毒力剂和抗生素佐剂	Moulding, P. B.	PDF	N/A	Discovery of broad-spectrum bacterial polyamine detoxification inhibitors as potential antivirulence agents and antibiotic adjuvants
脊髓灰质炎病毒的非裂解性传播需要非结构蛋白3CD的参与。	Aponte-Diaz, D.	PDF	N/A	Non-lytic spread of poliovirus requires the nonstructural protein 3CD
宿主内动态，连同基因型和表型效应，共同预测病毒突变的成功与否。	Tan, C. C. S.	PDF	N/A	Intrahost dynamics, together with genetic and phenotypic effects predict the success of viral mutations
Hsp90抑制剂结合的动态洞察：揭示中间态与构象可塑性	Sahil, M.	PDF	N/A	Dynamic Insights into Hsp90 Inhibitor Binding: Uncovering Intermediate States and Conformational Plasticity
PDZ激酶变构中继介导Par复合物调节剂交换	Vargas, E.	PDF	N/A	A PDZ-kinase allosteric relay mediates Par complex regulator exchange
Drp1介导的线粒体分裂保护巨噬细胞免受mtDNA/ZBP1介导的无菌性炎症，并抑制心肌梗死后心脏重塑。	Kondo, Y.	PDF	N/A	Drp1-mediated mitochondrial fission protects macrophages from mtDNA/ZBP1-mediated sterile inflammation and inhibits post-infarct cardiac remodeling
促进脂多糖被合成脂滴吸收的因素	Arnob, A.	PDF	N/A	Factors Promoting Lipopolysaccharide Uptake by Synthetic Lipid Droplets
甲硫基烷烃还原酶利用固氮酶金属簇进行碳硫键的断裂。	Lago-Maciel, A.	PDF	N/A	Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage
利用人工启动子、RNA适体和深度测序技术进行Sigma因子DNA结合序列的高分辨率绘图	Khan, E. A.	PDF	N/A	High-resolution mapping of Sigma Factor DNA Binding Sequences using Artificial Promoters, RNA Aptamers and Deep Sequencing
CRISPR-Cas9核糖核蛋白的包装递送加速了基因组编辑	Karp, H.	PDF	N/A	Packaged delivery of CRISPR-Cas9 ribonucleoproteins accelerates genome editing
氨基酸竞争塑造了鲍曼不动杆菌肠道携带	Ren, X.	PDF	N/A	Amino acid competition shapes Acinetobacter baumannii gut carriage
血吸虫感染对光滑双脐螺螺类微生物群的影响有限	Nordmeyer, S.	PDF	N/A	Limited Impact of Schistosome Infection on Biomphalaria glabrata Snail Microbiomes
YebC2 解决了多聚脯氨酸处的核糖体停滞问题，与 EF-P 和 ABCF ATPase YfmR 无关。	Hong, H.-R.	PDF	N/A	YebC2 resolves ribosome stalling at polyprolines independent of EF-P and the ABCF ATPase YfmR
一个信封应激反应通过一个小RNA调控长链脂肪酸代谢，以维持大肠杆菌中的氧化还原稳态。	Shrivastava, M.	PDF	N/A	An envelope stress response governs long-chain fatty acid metabolism via a small RNA to maintain redox homeostasis in Escherichia coli
从马来西亚环境中分离和鉴定降解聚(3HB)的细菌	Zahra, U.	PDF	N/A	Isolation and Identification of P(3HB)-Degrading Bacteria from Malaysian Environment
甲氧西林抗性对1株金黄色葡萄球菌毒力因子表达的影响：基于基因表达谱的见解	Gharsallah, C.	PDF	N/A	Impact of methicillin resistance on virulence factor expression in 1 Staphylococcus aureus: Insights from gene expression profiling
一种分布于植物共生细菌中的排出泵家族，能够条件性地对宿主特异性硫代葡萄糖苷进行宿主和器官特异性的解毒。	Russ, D.	PDF	N/A	An efflux pump family distributed across plant commensal bacteria conditions host- and organ-specific detoxfication of a host-specific glucosinolate
依赖磷酸化的mRNA脱腺苷化速率调控	Stowell, J. A.	PDF	N/A	Phosphorylation-dependent tuning of mRNA deadenylation rates
类组织多细胞发育由古菌中的机械压缩触发	Rados, T.	PDF	N/A	Tissue-Like Multicellular Development Triggered by Mechanical Compression in Archaea
放弃四极杆用于质谱碎片分析：通过高分辨率离子迁移前体隔离实现1,000赫兹速度与100%离子利用率	DeBord, D.	PDF	N/A	Abandoning the Quadrupole for Mass Spectrometry Fragmentation Analysis: Towards 1,000 Hz Speeds with 100% Ion Utilization Using High Resolution Ion Mobility Precursor Isolation
通过丝氨酸整合酶BxbI显著增强人类多能干细胞中的转基因整合	Autio, M. I.	PDF	N/A	Highly enhanced transgene integration in human pluripotent stem cells by serine integrase BxbI
# BioRxiv 2024-10-18 Papers

标题	作者	PDF链接	代码仓库	Title
刺激前大规模功能连接的动态变化决定了多感官任务中的表现	Galindo Leon, E. E.	PDF	N/A	Dynamic changes in large-scale functional connectivity prior to stimulation determine performance in a multisensory task
从单细胞和空间转录组学揭示的结直肠癌中空间定义的多细胞功能单元	Avraham-Davidi, I.	PDF	N/A	Spatially defined multicellular functional units in colorectal cancer revealed from single cell and spatial transcriptomics
一种含有催产素阳性物质的腰脊髓神经元群体调节性兴奋和交配行为。	Lenschow, C.	PDF	N/A	A galanin-positive population of lumbar spinal cord neurons modulates sexual arousal and copulatory behavior
脂质稳态受损通过ESCRT破坏导致溶酶体内源性蛋白聚集体的积累	Yong, J.	PDF	N/A	Impairment of lipid homeostasis causes lysosomal accumulation of endogenous protein aggregates through ESCRT disruption
老化大脑中广泛的不确定性调整抑制	Kosciessa, J. Q.	PDF	N/A	Broadscale dampening of uncertainty adjustment in the aging brain
通过肽距离分析评估TCR结合预测器的泛化能力	Castorina, L. V.	PDF	N/A	Assessing the Generalization Capabilities of TCR Binding Predictors via Peptide Distance Analysis
一种可调的极简细胞膜揭示出，两种脂质种类足以维持生命	Justice, I. G.	PDF	N/A	A tuneable minimal cell membrane reveals that two lipid species suffice for life
从自拍到科学 - 使用iPhone 13进行精确的3D叶片测量及其对植物发育和蒸腾作用的启示	Bar-Sella, G.	PDF	N/A	From Selfies to Science - Precise 3D Leaf Measurement with iPhone 13 and Its Implications for Plant Development and Transpiration
RmlT是一种调节李斯特菌单胞菌毒力的壁磷壁酸鼠李糖基转移酶的分子特性。	Monteiro, R.	PDF	N/A	Molecular properties of RmlT, a wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes.
在动物的近亲之一中，由盐度引发的克隆聚集性多细胞性	Ros-Rocher, N.	PDF	N/A	Clonal-aggregative multicellularity entrained by salinity in one of the closest relative of animals
在羧基末端结构域内带负电的区域维持了CTCF与DNA的正确结合。	Liu, L.	PDF	N/A	A negatively-charged region within carboxy-terminal domain maintains proper CTCF DNA binding
通过基因调控表型鉴定出的丹尼索瓦人候选化石	Mishol, N.	PDF	N/A	Candidate Denisovan fossils identified through gene regulatory phenotyping
预测帕金森病中病理学性丘脑底核β爆发的发生	Abdi-Sargezeh, B.	PDF	N/A	Prediction of pathological subthalamic nucleus beta burst occurrence in Parkinson's disease
前胫骨平移产生的大量制动力可诱导小鼠前十字韧带的自发性愈合	Saito, R.	PDF	N/A	Substantial Braking Force of Anterior Tibial Translation Induces the Spontaneous Healing of Murine Anterior Cruciate Ligament
刺激前β波功率在不同皮质区域介导显性和隐性知觉偏差	Forster, C.	PDF	N/A	Pre-stimulus beta power mediates explicit and implicit perceptual biases in distinct cortical areas
scCancerExplorer：一个综合数据库，用于交互式探索人类泛癌单细胞多组学数据	Huang, C.	PDF	N/A	scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer
机械拉伸足细胞中的选择性剪接作为肾小球高血压的模型	Mattias, F.	PDF	N/A	Alternative splicing in mechanically stretched podocytes as a model of glomerular hypertension
PA28γ通过提升线粒体功能，促进肿瘤的恶性进展，这一过程涉及C1QBP。	Wang, J.	PDF	N/A	PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
利用时间数据对调控内皮屏障完整性的激酶磷酸信号网络进行系统级重构	Wei, L.	PDF	N/A	Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data
内在动态在人脑对外部刺激的反应中起着重要作用。	Nentwich, M.	PDF	N/A	Intrinsic dynamic shapes responses to external stimulation in the human brain
预测无关信息：干扰项可预测性的神经效应取决于认知负荷	Lui, T. K.-Y.	PDF	N/A	Predicting the irrelevant: Neural effects of distractor predictability depend on load
刺胞动物胚胎中的平面细胞极性协调为动物体轴的进化提供了线索。	Uveira, J.	PDF	N/A	Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution
定性脑电图异常提示大脑网络向抑制主导型转变。EU-AIMS LEAP研究的结果显示了这一点。	Juarez-Martinez, E. L.	PDF	N/A	Qualitative EEG abnormalities signal a shift towards inhibition-dominated brain networks. Results from the EU-AIMS LEAP studies
海洋群岛进化辐射的生物地理学	Bree, B.	PDF	N/A	The biogeography of evolutionary radiations on oceanic archipelagos
解析苯基琥珀酸合酶的对映选择性机制：通过多尺度建模和动力学研究厌氧烃降解的启示	Szaleniec, M.	PDF	N/A	Unravelling the Enantioselective Mechanism of Benzylsuccinate Synthase: Insights into Anaerobic Hydrocarbon Degradation Through Multiscale Modelling and Kinetics
利用dCas引导的邻近标记技术在曲霉菌中进行位点特异性染色质蛋白质组学研究。	Svoboda, T.	PDF	N/A	Locus-specific chromatin proteomics using dCas-guided proximity labelling in Aspergillus nidulans.
从动物行为和福利的角度来看，监狱犬训练项目的效果如何？	Baria-Unwalla, P.	PDF	N/A	What's in it for the dogs? Assessing the outcomes of a prison-based dog training program from an animal behavior and welfare perspective
使用中位数对单细胞DNA甲基化数据中不可用值进行插补，既直接又有效。	Tang, S.	PDF	N/A	Imputing not available values in single-cell DNA methylation data using the median is straightforward and effective
利用微流控技术、延时相差显微镜和深度学习快速鉴定七种细菌种类	Hallström, E.	PDF	N/A	Rapid identification of seven bacterial species using microfluidics, time-lapse phase-contrast microscopy, and deep learning
人类星形胶质细胞同步化神经类器官网络	Patel, M. D.	PDF	N/A	Human Astrocytes Synchronize Neural Organoid Networks
FBXW7通过调节MYRF水平来控制成年中枢神经系统中髓鞘的容量和稳态	Collins, H. Y.	PDF	N/A	FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult CNS
通过组织特异性表达变化实现剂量敏感基因的进化	Rice, A. M.	PDF	N/A	Evolution of dosage-sensitive genes by tissue-restricted expression changes
暂时性脑缺血损害了血栓素A2的收缩作用，并诱导了高血压大鼠外周肠系膜动脉的肥厚性重塑，尽管长期使用亚油酰胺羟肟酸进行脑保护，但逆转效果有限。	Diaz-Perez, A.	PDF	N/A	Temporary cerebral ischaemia impairs thromboxane A2 constriction and induces hypertrophic remodelling in peripheral mesenteric arteries of hypertensive rats: limited reversal despite long-term suberoylanilide hydroxamic acid cerebroprotection
抑制PDGFRβ信号增强肌细胞融合以促进骨骼肌再生	Xue, S.	PDF	N/A	Suppressing PDGFRβ Signaling Enhances Myocyte Fusion to Promote Skeletal Muscle Regeneration
单轴力在青春期发育过程中改变乳腺导管网络的长度和导管的方向：来自计算建模和实验室实验的发现	George, U. Z.	PDF	N/A	Uniaxial force modifies the length of the mammary ductal network and the orientation of ducts during pubertal development: Findings from computational modeling and laboratory experiments
单轴力在青春期发育过程中改变乳腺导管网络的长度和导管的方向：来自计算建模和实验室实验的发现	George, U. Z.	PDF	N/A	Uniaxial force modifies the length of the mammary ductal network and the orientation of ducts during pubertal development: Findings from computational modeling and laboratory experiments
在净化选择下的家谱	Khudiakova, K. A.	PDF	N/A	Genealogies under purifying selection
估计利什曼原虫的有性生殖率和近交率	Nicoll, A. G.	PDF	N/A	Estimating the rate of sexual reproduction and the inbreeding rate in Leishmania
ybx1通过上游调控atoh1a，促进斑马鱼侧线神经丘毛细胞的快速再生。	Reagor, C. C.	PDF	N/A	ybx1 acts upstream of atoh1a to promote the rapid regeneration of hair cells in zebrafish lateral-line neuromasts
一种谱系特异性新生RNA检测揭示了组织生物学中基因调控的原理	Chovatiya, G.	PDF	N/A	A lineage-specific nascent RNA assay unveils principles of gene regulation in tissue biology
血小板单细胞转录组的首份全面描述	Wolfsberger, W.	PDF	N/A	The First Comprehensive Description of the Platelet Single Cell Transcriptome
转录组和文本的多模态学习使得通过自然语言聊天实现单细胞RNA测序数据的交互式探索成为可能。	Schaefer, M.	PDF	N/A	Multimodal learning of transcriptomes and text enables interactive single-cell RNA-seq data exploration with natural-language chats
在个性化基因组序列上训练深度学习模型可提高变异效应预测的准确性。	He, A. Y.	PDF	N/A	Training deep learning models on personalized genomic sequences improves variant effect prediction
用区间假设替代归一化方法可提高差异表达和差异丰度分析的严谨性和鲁棒性	McGovern, K. C.	PDF	N/A	Replacing Normalizations with Interval AssumptionsImproves the Rigor and Robustness of DifferentialExpression and Differential Abundance Analyses
人类拓扑异构酶IIα通过相变促进染色质凝聚	Wu, M.	PDF	N/A	Human Topoisomerase IIα Promotes Chromatin Condensation Via a Phase Transition
CcdA通过共翻译折叠机制保护CcdB免受不可逆错误折叠和聚集。	Bajaj, P.	PDF	N/A	CcdA chaperones CcdB against irreversible misfolding and aggregation via a cotranslational folding mechanism
无ECM的患者来源类器官保留了多样化的前列腺癌谱系，并揭示了体外富集的细胞类型	Dolgos, R.	PDF	N/A	ECM-free patient-derived organoids preserve diverse prostate cancer lineages and uncover in vitro-enriched cell types
RAS/PI3K通路突变使上皮性卵巢癌细胞对PARP/NAMPT抑制剂组合敏感	Gruet, M.	PDF	N/A	RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination
阿尔茨海默病APP/PS1雄性和雌性模型以及APPNL-F/NL-F雄性和雌性模型的寿命	Roberts, H.	PDF	N/A	Lifespan of male and female APP/PS1 and APPNL-F/NL-F mouse models of Alzheimer's disease
外源硒补充剂可减少镉在稻米中的积累，并恢复稻米中的微量营养素含量。	Barman, F.	PDF	N/A	Exogenous selenium supplements reduce cadmium accumulation and restores micronutrient content in rice grains
寄生植物的寄生虫在非传统阶段利用开花途径形成茎衍生的虫瘿。	Bessho-Uehara, K.	PDF	N/A	Parasitic-plant parasite utilizes flowering pathways at unconventional stages to form stem-derived galls
肠道细菌衍生的琥珀酸可诱导肠神经系统再生	Aydin, B.	PDF	N/A	Gut bacteria-derived succinate induces enteric nervous system regeneration
粘附G蛋白偶联受体ADGRG1促进阿尔茨海默病中保护性小胶质细胞反应	Zhu, B.	PDF	N/A	Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease
内侧前额叶皮层中的下边缘区，而非前边缘区，对于复杂的嗅觉记忆任务是必需的。	Jun, D. J.	PDF	N/A	The infralimbic, but not the prelimbic cortex is needed for a complex olfactory memory task.
神经肽动态协调分层可塑性机制，使果蝇昼夜节律行为适应变化的环境。	Chatterjee, A.	PDF	N/A	Neuropeptide Dynamics Coordinate Layered Plasticity Mechanisms Adapting Drosophila Circadian Behavior to Changing Environment.
整合时间进程分析：来自携带C9orf72、FUS、TARDBP和SOD1突变的ALS患者的iPSCs衍生运动神经元	Ma, G.	PDF	N/A	Integrated temporal profiling of iPSCs-derived motor neurons from ALS patients carrying C9orf72, FUS, TARDBP, and SOD1 mutations
H3K9me3的表观遗传去抑制通过免疫调节和Vgf诱导缓解了阿尔茨海默病相关病理，并改善了认知功能	Fuchs, D.-T.	PDF	N/A	Epigenetic derepression of H3K9me3 mitigates Alzheimer-related pathology and improves cognition via immunomodulation and Vgf induction
青光眼视网膜神经节细胞（RGC）死亡与眼压（IOP）诱导的血视网膜屏障破坏有关。	Zhang, C.	PDF	N/A	IOP-induced blood-retinal barrier compromise contributes to RGC death in glaucoma
胶质细胞衍生的通路引导再生视神经轴突向中枢神经系统中线方向生长。	Harvey, B. M.	PDF	N/A	Glial cell derived pathway directs regenerating optic nerve axons toward the CNS midline
腹内侧前额叶皮层的独特神经过程介导了注意力负荷的变化和尼古丁促进认知效应的作用	Vouillac-Mendoza, C.	PDF	N/A	Distinct neuronal processes in the ventromedial prefrontal cortex mediate changes in attention load and nicotine pro-cognitive effects
感觉运动整合增强了温度刺激的处理能力	Anderson, L. S.	PDF	N/A	Sensorimotor integration enhances temperature stimulus processing
糖酵解抑制功能性重编程T滤泡辅助细胞并逆转狼疮	Elshikha, A.	PDF	N/A	Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus
人类抗糖基化反应是由B细胞的选择驱动的，这些B细胞利用了在生发中心中亲和力成熟的私人抗体基因重排。	New, J. S.	PDF	N/A	Human Anti-Glycan Reactivity is Driven by the Selection of B cells Utilizing Private Antibody Gene Rearrangements that are Affinity Maturated in Germinal Centers
一种来自激活的CD4 T细胞的外泌体资源，用于传递促炎信号	Jainarayanan, A. K.	PDF	N/A	A resource for extracellular vesicles from activated CD4 T cells that relay pro-inflammatory signals
CD4+ T细胞中G蛋白信号调节因子2敲除促进抗炎T细胞，增强排卵和卵母细胞产量	Raff, M.	PDF	N/A	Regulator of G-Protein Signaling 2 Knockout in CD4+ T Cells Promotes Anti-Inflammatory T Cells, Enhancing Ovulation, and Oocyte Yield
全球RNA病毒组潜在辅助代谢基因（AMGs）的功能和进化特征	Zhao, Y.	PDF	N/A	Functional and evolutionary characterization of potential auxiliary metabolic genes (AMGs) of the global RNA virome
佛罗里达灌木丛中地衣多样性和丰度调查：与烧伤恢复各个时间阶段的关系	Holst, M. M.	PDF	N/A	Survey of Lichen Diversity and Abundance in a Florida Scrub in Relation to Various Temporal Stages of Burn Recovery
NicheFlow：迈向物种分布建模的基础模型	Dinnage, R.	PDF	N/A	NicheFlow: Towards a foundation model for Species Distribution Modelling
应用基于发生概率的贝叶斯模型评估环境梯度对塞拉多溪流中水生昆虫属种更替的影响	Godoy, B. S.	PDF	N/A	Application of a Bayesian model based on probability of occurrence to evaluate the effect of an environmental gradient on the turnover of aquatic insect genera in Cerrado streams
表观基因组的趋同进化在生命之树中招募了DNA修复	Monroe, G.	PDF	N/A	Convergent evolution of epigenome recruited DNA repair across the Tree of Life
贝克尔肌营养不良症小鼠表现出骨骼肌中IIa型纤维的部位特异性退化，并伴有毛细血管变化。	Miyazaki, D.	PDF	N/A	Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle
稳定选择和适应塑造了秀丽隐杆线虫中顺式和反式基因表达变异	Bell, A. D.	PDF	N/A	Stabilizing selection and adaptation shape cis and trans gene expression variation in C. elegans
重建真核生物中RNA结合蛋白的序列特异性	Sasse, A.	PDF	N/A	Reconstructing the sequence specificities of RNA-binding proteins across eukaryotes
微小RNA 7975直接调控MDTH表达，并在早期动脉粥样硬化的发展中介导内皮细胞的增殖和迁移。	Karere, G.	PDF	N/A	Micro-RNA 7975 directly regulates MDTH expression and mediates endothelial cell proliferation and migration in the development of early atherosclerosis
可遗传的非遗传表型在压力反应中富集，作为对冲的一种形式。	Grissom, S.	PDF	N/A	Heritable non-genetic phenotypes are enriched for stress responses as a form of bet hedging
通过共价纳米孔检测实现挥发性有机化合物的高分辨率靶向传感	McGivern, L. E.	PDF	N/A	Targeted, high-resolution sensing of volatile organic compounds by covalent nanopore detection
从牛胚胎干细胞生成培养牛肉	Rui, X.	PDF	N/A	Generation of cultured beef from bovine embryonic stem cells
快速单细胞基质辅助激光解吸电离成像技术揭示低分子量代谢物的细胞激活标志物	Cairns, J. L.	PDF	N/A	Fast Single-Cell MALDI Imaging of Low-Mass Metabolites Reveals Cellular Activation Markers
通过减法蛋白质组学揭示D-丙氨酸-D-丙氨酸连接酶作为伯克霍尔德菌假单胞菌药物靶点的潜力	Rahman, S.	PDF	N/A	Subtractive proteomics unravel the potency of D-Alanine-D-Alanine Ligase as the drug target for Burkholderia pseudomallei
利用单细胞RNA测序图谱进行抗体面板的交互设计与验证	Watson, M.	PDF	N/A	Interactive design and validation of antibody panels using single-cell RNA-seq atlases
CELL-Diff：统一扩散建模用于蛋白质序列和显微镜图像	Zheng, D.	PDF	N/A	CELL-Diff: Unified diffusion modeling for protein sequences and microscopy images
Carafe能够为数据非依赖性采集蛋白质组学生成高质量的计算机模拟光谱库。	Wen, B.	PDF	N/A	Carafe enables high quality in silico spectral library generation for data-independent acquisition proteomics
利用AlphaFold2探索电压门控钠通道的构象及蛋白质-蛋白质相互作用	Mateos, D. L.	PDF	N/A	Exploring voltage-gated sodium channel conformations and protein-protein interactions using AlphaFold2
HP1a促进染色质流动性并驱动自发异染色质区室化	Brennan, L. D.	PDF	N/A	HP1a promotes chromatin liquidity and drives spontaneous heterochromatin compartmentalization
渗透型临界阈值控制着免疫蛋白对表面的覆盖	Wang, Z.	PDF	N/A	A percolation-type criticality threshold controls immune protein coating of surfaces
在转录过程中，染色质缓冲扭转应力	Qian, J.	PDF	N/A	Chromatin Buffers Torsional Stress During Transcription
基于负载的差异在两个识别相同pMHC的TCR的动态别构效应中	Chang-Gonzalez, A. C.	PDF	N/A	Load-based divergence in the dynamic allostery of two TCRs recognizing the same pMHC
在冷冻电子断层扫描技术下观察到的病毒相关流感血凝素在结合唾液酸后形成的簇状结构	Huang, Q. Y.	PDF	N/A	Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography
每周吸入沙美特罗西那非，一种选择性β2肾上腺素受体激动剂药物，在体内治疗性地抑制癌症生长并延长生存期。	She, X.	PDF	N/A	Weekly inhaled salmeterol xinafoate, a selective β2 adrenergic receptor agonist drug, therapeutically inhibits cancer growth and prolongs survival in vivo
支链氨基酸分解代谢通过mTOR的磷酸化促进卵巢癌细胞增殖	Lusk, H. J.	PDF	N/A	Branched-chain amino acid catabolism promotes ovarian cancer cell proliferation via phosphorylation of mTOR
氯硝柳胺前药增强口服生物利用度并靶向肝细胞癌中的Vasorin-TGFβ信号通路	Tan, M.	PDF	N/A	Niclosamide Prodrug Enhances Oral Bioavailability and Targets Vasorin-TGFβ Signaling in Hepatocellular Carcinoma
患者来源的ccRCC肿瘤细胞的长读长空间转录组分析揭示了异构体和基因表达的异质性	Elshani, M.	PDF	N/A	Long-read Spatial Transcriptomic Profiling of Patient-derived ccRCC Tumoroids Reveals Heterogeneity in Isoform and Gene Expression
肿瘤内CXCL12梯度在乳腺癌中情境化肿瘤细胞侵袭、迁移及免疫抑制	Anastasiadou, D. P.	PDF	N/A	Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer
脂质纳米颗粒共递送紫杉醇和大麻二酚增强对黑色素瘤细胞的细胞毒性	de Carvalho, F. V.	PDF	N/A	Co-delivery of Paclitaxel and Cannabidiol in Lipid Nanoparticles Enhances Cytotoxicity Against Melanoma Cells
印度儿童B细胞急性淋巴细胞白血病患者中CD19外显子5-6跳跃现象普遍存在	Srivastava, D.	PDF	N/A	Widespread Prevalence of CD19 Exon 5-6 Skipping In Indian Pediatric B-cell Acute Lymphoblastic Leukemia Patients
西酞普兰通过调节C5aR1+肿瘤相关巨噬细胞（TAMs）和CD8+ T细胞，展现出依赖免疫的抗肿瘤效应。	Dong, F.	PDF	N/A	Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs and CD8+ T cells
速度幅值和周期影响正弦速度变化条件下的步态变异性和步跟随性	Motoyama, K.	PDF	N/A	Speed amplitude and period affect gait variability and step followability under sinusoidal speed changing conditions
踝跖屈过程中肌腱微振动强度增加的轨迹：使用潜在曲线模型的纵向数据分析	Matsumoto, T.	PDF	N/A	Increase trajectories of tendon micro vibration intensity during ankle plantar flexion: A longitudinal data analysis using latent curve models
生长素（IAA）及其在复杂轮藻（Chara braunii）中的运输作用	Kurtovic, K.	PDF	N/A	The role of IAA and its transport in the complex streptophyte algae Chara braunii
黄羽扇豆（Lupinus luteus）对黄羽扇豆炭疽菌（Colletotrichum lupini）的防御机制，涉及TIR-NBS-LRR蛋白、过敏反应及苯丙烷途径	Godoy, G. A.	PDF	N/A	Defense mechanisms in Lupinus luteus against Colletotrichum lupini, involving TIR-NBS-LRR protein, hypersensitive response and phenylpropanoid pathways
回顾NIP2同源基因在Rhynchosporium spp.复合体中的进化与功能	Darma, R.	PDF	N/A	Revisiting the evolution and function of NIP2 parologs in the Rhynchosporium spp. complex
转移到不同寄主葡萄藤会导致专食性昆虫Daktulosphaira vitifoliae迅速且广泛地转录可塑性变化	Collison, W. N.	PDF	N/A	Transfer to different host grapevines causes rapid and widespread transcriptional plasticity in the specialist insect Daktulosphaira vitifoliae
动态多组学与机制建模方法揭示了肾纤维化进展的新机制	Tuechler, N.	PDF	N/A	Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression
清醒状态下的蟾蜍大脑活动的慢性记录	Shaykevich, D. A.	PDF	N/A	Chronic recording of brain activity in awake toads
长期过度活跃引发培养的海马齿状颗粒细胞亚群中大量且持续的氯离子重新分布	Takano, H.	PDF	N/A	Prolonged Hyperactivity Elicits Massive and Persistent Chloride Ion Redistribution in Subsets of Cultured Hippocampal Dentate Granule Cells
在正常的产后发育过程中，暗色小胶质细胞大量存在，它们通过吞噬作用和细胞穿孔作用重塑突触，并且依赖于TREM2。	Vecchiarelli, H. A.	PDF	N/A	Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2
用于预测小鼠决策过程中神经回路的真实-网络混合神经网络	Ueoka, Y.	PDF	N/A	Real-cyber hybrid neural network for predicting neural circuits in mouse decision-making
青少年亨廷顿病R6/2小鼠模型中的皮层纹状体发育不良	Cepeda, C.	PDF	N/A	Corticostriatal Maldevelopment in the R6/2 Mouse Model of Juvenile Huntington Disease
持续注意力期间的警觉性、任务诱发的疲劳和动机：解耦的α波和β波特征的证据	Hanzal, S.	PDF	N/A	EEG markers of vigilance, task-induced fatigue and motivation during sustained attention: Evidence for decoupled alpha- and beta-signatures
尾索动物布氏菊海鞘（Botryllus schlosseri）中同种识别受体的遗传和功能多样性	Rodriguez-Valbuena, H.	PDF	N/A	Genetic and functional diversity of allorecognition receptors in the urochordate, Botryllus schlosseri
肺上皮祖细胞介导的TGF-β释放调控黏膜卡介苗接种后肺CD8+ TRM细胞的诱导与持久性	Blake, J. A.	PDF	N/A	Lung epithelial progenitor-mediated release of TGF-β regulates induction and persistence of lung CD8+ TRM cells following mucosal BCG vaccination
肿瘤内预先存在的干细胞样CD8+ T细胞驱动放射治疗诱导的肿瘤控制	Koksal, H.	PDF	N/A	Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control
在亚热带海洋生态系统的透光层中，寄生和自养主导的原生生物群落的转换与季节性寡营养-中营养梯度相耦合。	Avrahami, Y.	PDF	N/A	Switch in parasitic and autotrophic-dominated protist assemblages coupled to seasonal oligotrophic-mesotrophic gradients in the sunlit layer of a subtropical marine ecosystem
一个简单的基于有益和有害相互作用网络的人口动态模型，适用于实证研究。	Bimler, M. D.	PDF	N/A	A simple model of population dynamics with beneficial and harmful interaction networks for empirical applications.
雌性推动了果蝇物种交配后生殖特征的进化，但并非通过再交配率来实现。	Peckenpaugh, B.	PDF	N/A	Females drive postmating reproductive trait evolution across Drosophila species, but not via remating rate
身体大小和适应度匹配及其对温度可塑性反应的变异性	Zygadlo, A.	PDF	N/A	The body size and fitness match and its variability in plastic response to temperature
关岛（马里亚群岛）上两种共存的近缘前礁珊瑚物种的进化基因组学研究。	Torrado, H.	PDF	N/A	Evolutionary genomics of two co-occurring congeneric fore reef coral species on Guam (Mariana Islands).
cGAS-STING通路是基因组不稳定综合征的内源性修饰因子。	Bergman, M.	PDF	N/A	The cGAS-STING pathway is an in vivo modifier of genomic instability syndromes
利用转录组学研究麦二叉蚜与小麦的相互作用	Swiegers, H. W.	PDF	N/A	Investigating the Diuraphis noxia-Triticum aestivum interaction using transcriptomics
夜间的人工光照增强了水生碎屑者在捕食风险下的防御行为	Rufaida, Z.	PDF	N/A	Artificial light at night enhances the defensive behavior in aquatic shredders under predation risk
硫烯素的发现及其新发现的酰基亚硫酸酯功能团的生物合成	Xue, D.	PDF	N/A	Discovery and Biosynthesis of Sulfenicin and Its New-to-Nature Acylsulfenic Acid Functional Group
Du-IN-v2：释放向量量化的力量，从颅内神经信号解码认知状态	Zheng, H.	PDF	N/A	Du-IN-v2: Unleashing the Power of Vector Quantization for Decoding Cognitive States from Intracranial Neural Signals
从模拟到推断：利用机器学习调整针对特定患者的耳中有限元模型，以实现客观诊断	Motallebzadeh, H.	PDF	N/A	From Simulations to Inference: Using Machine Learning to Tune Patient-Specific Finite-Element Models of the Middle Ear Towards Objective Diagnosis
天然保湿因子对皮肤保湿的作用，是一个关于氢键网络的故事。	MARTIN, M.	PDF	N/A	Skin hydration by natural moisturizing factors, a story of H-bond networking
一种综合性的空间多组学工作流程，用于统一分析肿瘤组织	Kriel, J.	PDF	N/A	An integrative spatial multi-omic workflow for unified analysis of tumor tissue
气溶胶化合物对肺表面活性物质破坏的实验与建模	Barlow, H. J.	PDF	N/A	Experiments and modelling of pulmonary surfactant disruption by aerosolised compounds
绘制二氢蝶酸合成酶（DHPS）的可进化性图谱：通过进化和结构分析鉴定新型进化关键子结构	Sanyal, D.	PDF	N/A	Mapping DHPS Evolvability: Identification of Novel Evolutionarily Critical Sub-Structure through Evolutionary and Structural Analyses of DHPS
自愿运动减轻了去势抵抗性前列腺癌临床前模型中的肿瘤生长	Berger, N.	PDF	N/A	Voluntary Exercise Attenuates Tumor Growth in a Preclinical Model of Castration-Resistant Prostate Cancer
通过FGFR2的消除来拦截导管胰腺癌	Tonelli, C.	PDF	N/A	Ductal pancreatic cancer interception by FGFR2 abrogation
PRMT5介导的组蛋白甲基化通过MECP2-PTBP1调控选择性剪接，促进乳腺癌缺氧环境下的上皮-间质转化（EMT）。	Mutnuru, S. A.	PDF	N/A	PRMT5-mediated histone methylation regulates alternative splicing via MECP2-PTBP1 to promote EMT in breast cancer hypoxia
Path2Space：一种通过组织病理学推断的空间转录组学AI方法用于癌症生物标志物发现	Shulman, E. D.	PDF	N/A	Path2Space: An AI Approach for Cancer Biomarker Discovery Via Histopathology Inferred Spatial Transcriptomics
通过蛋白质组学解析结直肠癌中的硬度驱动变化	Cresens, C.	PDF	N/A	Deciphering stiffness-driven changes in colorectal cancer by proteomics
药物蛋白质组学分析鉴定出异常药物作用的分泌标志物	Knecht, S.	PDF	N/A	Pharmacoproteomic profiling identifies secreted markers for aberrant drug action
CCK1受体在小鼠肠道肠肽酶抑制代谢益处中的作用	Hinke, S. A.	PDF	N/A	Role of CCK1 receptor in metabolic benefits of intestinal enteropeptidase inhibition in mice
冷冻保护剂合成的可塑性涉及从丙酮酸生产中协调分流。	van der Burg, K. R. L.	PDF	N/A	Plasticity in cryoprotectant synthesis involves coordinated shunting away from pyruvate production
探究棉花CMF基因在盐胁迫耐受性中的作用：来自系统发育、表达和功能分析的见解	Cui, Y.	PDF	N/A	Exploring the Role of Cotton CMF Genes in Salt Stress Tolerance: Insights from Phylogenetic, Expression, and Functional Analyses
雄性和雌性配子体在冬季相遇：检验日本石栎延迟受精的越冬假说	Shagawa, T.	PDF	N/A	Male and female gametophytes meet after winter: Testing the overwintering hypothesis for delayed fertilization in Japanese stone oak
植物表型分化在塑造生菜叶微生物群方面比遗传变异更为重要。	Capparotto, A.	PDF	N/A	Plant phenotypic differentiation outweighs genetic variation in shaping the lettuce leaf microbiota
桃树TNL RMia基因的鉴定与表达，用于抵抗根结线虫Meloidogyne incognita	Duval, H.	PDF	N/A	Identification and Expression of the peach TNL RMia genes for the Resistance to the Root-knot Nematode Meloidogyne incognita
干细胞诱导转录因子WUSCHEL的细胞间移动受运输与保留的平衡调控。	Fuchs, M.	PDF	N/A	Cell-to-cell mobility of the stem cell inducing WUSCHEL transcription factor is controlled by a balance of transport and retention
气道树的几何分析表明，肺部解剖结构在鲸类动物中进化，以实现爆炸性通气并防止气压伤。	Cieri, R.	PDF	N/A	Geometric analysis of airway trees shows that lung anatomy evolved to enable explosive ventilation and prevent barotrauma in cetaceans
地下啮齿动物埃洛波斯塔普努斯两个种群的遗传多样性和精细尺度结构	Rudyk, A. I.	PDF	N/A	Genetic diversity and fine-scale structure of two populations of a subterranean rodent, Ellobius talpinus
一种深度学习方法，用于检测和可视化单型物种中的性二态性	Silva, N. J.	PDF	N/A	A deep learning approach to detect and visualise sexual dimorphism in monomorphic species
微扫视引起的知觉填充延迟与刺激依赖性	Levinson, M.	PDF	N/A	Stimulus-dependent delay of perceptual filling-in by microsaccades
长程轴突形态的计算生成	Berchet, A.	PDF	N/A	Computational generation of long-range axonal morphologies
巨噬细胞与神经前体细胞和成纤维细胞的相互作用通过Sema4ab控制斑马鱼脊髓损伤后的再生性神经发生	Docampo Seara, A.	PDF	N/A	Macrophage crosstalk with neural progenitors and fibroblasts controls regenerative neurogenesis via Sema4ab after spinal cord injury in zebrafish
CXCL10/CXCR3信号通路诱导神经衰老和认知障碍	Patel, M.	PDF	N/A	CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments
星形胶质细胞Ryk信号在脊髓损伤后协调瘢痕形成和伤口愈合	Shen, Z.	PDF	N/A	Astrocytic Ryk signaling coordinates scarring and wound healing after spinal cord injury
线粒体不存在于执行监视、趋化性和吞噬性吞噬的微胶质突触中。	Pietramale, A. N.	PDF	N/A	Mitochondria are absent from microglial processes performing surveillance, chemotaxis, and phagocytic engulfment
通过AP-1调控轴限制先天性Tγδ17细胞的可塑性	Parker, M. E.	PDF	N/A	Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis
在C. elegans早期胚胎中，Topoisomerase 2/condensin II轴耗竭后的转录组分析。	Belew, M. D.	PDF	N/A	Transcriptome analysis in C. elegans early embryos upon depletion of the Topoisomerase 2/condensin II axis.
通过海绵组织采集利用环境DNA宏条形码技术研究大型地中海潟湖的空间和季节性生物多样性变化	Corral-Lou, A.	PDF	N/A	Spatial and seasonal biodiversity variation in a large Mediterranean lagoon using environmental DNA metabarcoding through sponge tissue collection
较弱的neuroligin 2-neurexin 1β相互作用通过聚集锚定膜并促进突触生成	Boyd, R.	PDF	N/A	Weaker neuroligin 2-neurexin 1β interaction tethers membranes and signal synaptogenesis through clustering
从富含乳糖的废水中生产乳酸：比较反应器配置以最大化转化率和效率的研究	Temovska, M.	PDF	N/A	Lactate production from lactose-rich wastewater: A comparative study on reactor configurations to maximize conversion rates and efficiencies
AI-QuIC：用于种子扩增实验中自动检测错误折叠蛋白质的机器学习	Howey, K. D.	PDF	N/A	AI-QuIC: Machine Learning for Automated Detection of Misfolded Proteins in Seed Amplification Assays
a2iHelper：一个用于RNA-Seq数据差异编辑位点分析的Python工具包	Ribas, G. T.	PDF	N/A	a2iHelper: a Python toolkit for a differential editing site analysis of RNA-Seq data
通过高浓度聚集调节异源甘氨酸受体功能	Yu, H.	PDF	N/A	Modulation of heteromeric glycine receptor function through high concentration clustering
Src家族激酶抑制剂药物达沙替尼与糖皮质激素联合使用，对舌鳞状细胞癌显示出协同作用，并能降低MET激酶活性。	Hmedat, A. N. A.	PDF	N/A	The Src family kinase inhibitor drug Dasatinib and glucocorticoids display synergistic activity against tongue squamous cell carcinoma and reduce MET kinase activity
临床来源人体组织数字空间分析的严谨性与可重复性	Smith, K. D.	PDF	N/A	Rigor and Reproducibility of Digital Spatial Profiling on Clinically Sourced Human Tissues
揭示SH3PXD2B在驱动乳腺癌肺转移的上皮间质转化中的作用	Das, S.	PDF	N/A	Unlocking the role of SH3PXD2B in epithelial-to-mesenchymal transition driving Breast Cancer Lung Metastasis
睡眠诱导的血管运动脉动是人类大脑中脑脊液和血脑屏障动态变化的一个驱动因素	Väyrynen, T.	PDF	N/A	Sleep-Induced Vasomotor Pulsation is a Driver of Cerebrospinal Fluid and Blood-Brain Barrier Dynamics in the Human Brain
光遗传学诱导的蛋白质聚集与邻近生物素化测定相结合，强烈暗示内溶酶体蛋白在α-突触核蛋白聚集的早期阶段发挥作用。	Teixeira, M.	PDF	N/A	The combination of optogenetic-induced protein aggregation and proximity biotinylation assays strongly implicates endolysosomal proteins in the early stages of α-synuclein aggregation
非侵入性光学监测新生儿脑室内出血的临床前模型中的脑血流动力学	Jethe, J. V.	PDF	N/A	Noninvasive optical monitoring of cerebral hemodynamics in a preclinical model of neonatal intraventricular hemorrhage
通过全面数据分析进行中风结果预测的基准测试 - NeuralCup 2023	Matsulevits, A.	PDF	N/A	Benchmarking Stroke Outcome Prediction through Comprehensive Data Analysis - NeuralCup 2023
KCNQ2/3 K+通道中功能性与轴突始段运输之间的耦合	Yoshioka, D.	PDF	N/A	Coupling Between Functionality and Trafficking to the Axon Initial Segment in KCNQ2/3 K+ Channels
神经退行性变小鼠模型和人类疾病中TMEM106B病理的分化与趋同	Du, M.	PDF	N/A	Divergent and Convergent TMEM106B Pathology in Murine Models of Neurodegeneration and Human Disease
意识的人工智能驱动模型，及其障碍与治疗	Toker, D.	PDF	N/A	An AI-Driven Model of Consciousness, Its Disorders, and Their Treatment
偏相关作为绘制人脑连接中功能-结构对应关系的工具	Santucci, F.	PDF	N/A	Partial Correlation as a Tool for Mapping Functional-Structural Correspondence in Human Brain Connectivity
接触含有轮胎和道路磨损颗粒（TRWPs）的城市沉积物复合混合物会增加摇蚊（Chironomus riparius）的种系突变率。	Rigano, L.	PDF	N/A	Exposure to complex mixtures of urban sediments containing Tyre and Road Wear Particles (TRWPs) increases the germ-line mutation rate in Chironomus riparius
使用机器学习预测天然酵母的表型景观	Khaiwal, S.	PDF	N/A	Predicting the natural yeast phenotypic landscape with machine learning
非随机交配和环境传播偏差的简单模型对标准人类遗传学统计方法提出了挑战	Border, R.	PDF	N/A	Simple models of non-random mating and environmental transmission bias standard human genetics statistical methods
甲基化时钟并不能预测基因混合个体的年龄或阿尔茨海默病风险	Cruz-Gonzalez, S.	PDF	N/A	Methylation Clocks Do Not Predict Age or Alzheimer's Disease Risk Across Genetically Admixed Individuals
小鼠肝脏的昼夜节律异构体图谱	Zee, A.	PDF	N/A	The Circadian Isoform Landscape of Mouse Livers
雄性和雌性大鼠在平台介导的回避行为中的泛化和消退	Lppez-Moraga, A.	PDF	N/A	Generalization and extinction of platform-mediated avoidance in male and female rats
为什么蝙蝠会飞进洞穴的门？回声定位动物的注意力缺失性失明	Finger, N. M.	PDF	N/A	Why do bats fly into cave doors? Inattentional blindness in echolocating animals
初级短跑各阶段影响表现关键因素的演变	Oku, K.	PDF	N/A	Evolution of Key Factors Influencing Performance Across Phases in Junior Short Sprints
在新热带慈鲷中，面部颜色作为一种社会信号：测试面部表情假说	Satoh, S.	PDF	N/A	Facial Coloration as a Social Signal in a Neotropical Cichlid: Testing the Facial Expression Hypothesis
利用体外动态力学加载的小鼠后肢培养，实现临界尺寸缺损的胫前肌（TA）再生	Jacho, D.	PDF	N/A	Critical-Size Defect Tibialis Anterior (TA) Muscle Regeneration using Ex-Vivo Mice Hindlimbs Culturing under Dynamic Mechanical Loading
解析人类视网膜内的发展异质性，以重建视网膜神经节细胞成熟过程的连续性及特定阶段的内在和外在因素	Kriukov, E.	PDF	N/A	Unraveling the developmental heterogeneity within the human retina to reconstruct the continuity of retinal ganglion cell maturation and stage-specific intrinsic and extrinsic factors
利用特征架构感知的直系同源分配，追踪植物细胞壁降解酶在整个生命树中的分类分布	Tran, V.	PDF	N/A	Tracing the taxonomic distribution of plant cell wall degrading enzymes across the tree of life using feature architecture aware orthology assignments
一种用于细菌基因组DNA提取和分析的微流控平台	Joesaar, A.	PDF	N/A	A microfluidic platform for extraction and analysis of bacterial genomic DNA
人类TRPV4工程产生了一种对超声敏感的驱动器，用于声遗传学	Zhao, L.	PDF	N/A	Human TRPV4 engineering yields an ultrasound-sensitive actuator for sonogenetics
力依赖性重组与机械稳定性：涉及人类受精的Izumo1:Juno复合体的研究	Boult, S.	PDF	N/A	Force-dependent Reorganization and Mechanostability of the Izumo1:Juno Complex Involved in Human Fertilization
联邦深度学习通过蛋白质组学实现癌症亚型分类	Cai, Z.	PDF	N/A	Federated deep learning enables cancer subtyping by proteomics
体内CRISPRi筛选鉴定出对皮肤鳞状细胞癌肿瘤生长至关重要的lncRNA组合	Kim, G.	PDF	N/A	In vivo CRISPRi screen identified lncRNA portfolio crucial for cutaneous squamous cell carcinoma tumor growth
TCA循环中的热力学瓶颈导致金黄色葡萄球菌中乙酸的溢出。	Shahreen, N.	PDF	N/A	A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus
热蛋白质组分析揭示了特定细胞区室中氧化还原变化引起的快速蛋白质组反应	Revazian, A.	PDF	N/A	Thermal Proteome Profiling reveals rapid proteomic responses to redox changes in specific cellular compartments
开发并验证了一个开源的“手性判断任务”，适用于面对面和在线研究	Moreno-Verdu, M.	PDF	N/A	Development and validation of an open-source Hand Laterality Judgement Task for in-person and online studies
通过机器学习和转录组整合阐明阿尔茨海默病中淀粉样蛋白-β和tau的神经病理学及分子异质性	Zhao, K.	PDF	N/A	Elucidating the neuropathological and molecular heterogeneity of amyloid-beta and tau in Alzheimer's disease through machine learning and transcriptomic integration
在稳定的选择-反应关联期间，抽象的选择表征	Quinn, K. R.	PDF	N/A	Abstract choice representations during stable choice-response associations
艺术中的隐秘拓扑：一扇通往人类感知之窗	Dmitriuk, E.	PDF	N/A	Art's Hidden Topology: A window into human perception
一种针对α-突触核蛋白聚集物的脑穿梭抗体，用于治疗突触核蛋白病	An, S.	PDF	N/A	A brain-shuttled antibody targeting alpha synuclein aggregates for the treatment of synucleinopathies
对免疫组库数据的统计分析显示了微同源性在V(D)J重组中的影响。	Russell, M. L.	PDF	N/A	Statistical analysis of repertoire data demonstrates the influence of microhomology in V(D)J recombination
探索硫酸乙酰肝素类似物OTR4120的抗纤维化潜力：来自临床前模型的见解	Marega, M.	PDF	N/A	Exploring the Antifibrotic Potential of the heparan sulfate mimetic OTR4120: Insights from Preclinical Models
BBATProt：一种通过可解释深度学习增强特征提取的生物功能预测框架	Wang, Y.	PDF	N/A	BBATProt: A Framework Predicting Biological Function with Enhanced Feature Extraction via Explainable Deep Learning
BioStructNet：基于结构的网络与迁移学习相结合用于预测生物催化剂功能	Wang, X.	PDF	N/A	BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions
一种用于预测和设计可成药蛋白质的集成方法。	Jain, S.	PDF	N/A	An ensemble method for predicting and designing of druggable proteins.
在spastin中，一个与疾病相关的主要点突变显著改变了其动力学和变构效应。	Kahawatte, S.	PDF	N/A	A major disease-related point mutation in spastin alters dramatically the dynamics and allostery of the motor
磷酸化在两种与膜相关的凝聚态之间切换SARS-CoV-2核衣壳蛋白的状态	Favetta, B.	PDF	N/A	Phosphorylation Toggles the SARS-CoV-2 Nucleocapsid Protein Between Two Membrane-Associated Condensate States
芳香族氨基酸相互作用强度的交叉：酪氨酸与苯丙氨酸在生物分子凝聚物中的比较	De Sancho, D.	PDF	N/A	Crossover in Aromatic Amino Acid Interaction Strength: Tyrosine vs. Phenylalanine in Biomolecular Condensates
GBM中GABARAPs的差异表达以p53依赖的方式赋予替莫唑胺敏感性	Megha,	PDF	N/A	Differential expression of GABARAPs in GBM renders temozolomide sensitivity in a p53-dependent manner
SSTR2靶向的肝细胞癌治疗诊断学	Momeny, M.	PDF	N/A	SSTR2-targeted theranostics in hepatocellular carcinoma
脱氧神经鞘脂在结肠癌细胞中激活cGAS-STING，并增强肿瘤免疫	Saha, S.	PDF	N/A	Deoxysphingolipids activate cGAS-STING in colon cancer cells and enhance tumor immunity
从全基因组层面探究桃金娘HSF基因家族及其在热适应中的功能特征	Li, H.-G.	PDF	N/A	A genome-wide-level insight into HSF gene family of Rhodomyrtus tomentosa and the functional characterization of RtHSFA2s genes in thermal adaption
基于代理的拟南芥合子中皮质微管带运动的模拟	Nonoyama, T.	PDF	N/A	Agent-Based Simulation of Cortical Microtubule Band Movement in the Arabidopsis Zygote
多束神经复合动作电位的模拟分析	Tharayil, J. J.	PDF	N/A	Simulation Insights on the Compound Action Potential in Multifascicular Nerves
非侵入性脑刺激对神经纤维瘤1型患者工作记忆任务期间有效连通性的影响	Litwinczuk, M. C.	PDF	N/A	Effects of non-invasive brain stimulation on effective connectivity during working memory task in Neurofibromatosis Type 1 patients
B细胞表达的酶PexRAP，作为醚脂生物合成中的中间体，促进了抗体反应和生发中心的大小。	Cho, S. H.	PDF	N/A	B cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size
纳米材料会引发人体免疫细胞的功能反应。	Mittelheisser, V.	PDF	N/A	Nanomaterials trigger functional responses in primary human immune cells
腺病毒26型载体疫苗在小鼠中引发的免疫反应的早期时空演变	Blass, E.	PDF	N/A	Early spatiotemporal evolution of the immune response elicited by adenovirus serotype 26 vector vaccination in mice
绘制微生物真核生物细胞骨架多样性的图景	Mikus, F.	PDF	N/A	Charting the landscape of cytoskeletal diversity in microbial eukaryotes
使用时间延迟积分技术的拉曼流式细胞仪	Lindley, M.	PDF	N/A	Raman flow cytometry using time delay integration
未能再现程序性记忆干扰对年轻和老年成人清醒状态下情景记忆巩固的影响	Kamal, L.	PDF	N/A	Failure to reproduce the effect of procedural memory interference on wakeful consolidation of episodic memory in younger and older adults
登革病毒2型八面体小病毒样颗粒	Johnson, A.	PDF	N/A	Octahedral small virus-like particles of dengue virus type 2
血影蛋白协调皮质肌动蛋白-肌球蛋白的组织和分化，这对功能性上皮屏障至关重要。	Soffer, A.	PDF	N/A	Spectrin coordinates cortical actomyosin organization and differentiation essential for a functional epithelial barrier
在CRISPR/Cas介导的染色体倒位后，表观遗传状态和基因表达保持稳定。	Khosravi, S.	PDF	N/A	Epigenetic state and gene expression remain stable after CRISPR/Cas-mediated chromosomal inversions
靶向长链非编码RNA RP11-502I4.3可延缓糖尿病视网膜病变中的血管生成趋势	Tan, W.	PDF	N/A	Targeting long non-coding RNA RP11-502I4.3 delays the trend of angiogenesis in diabetic retinopathy
PD-L1+ 中性粒细胞在非酒精性脂肪肝病中的系统性炎症反应期间介导易感性	Barros, C. d. C. O.	PDF	N/A	PD-L1+ Neutrophils mediate Susceptibility during Systemic Inflammatory Response in Non-Alcoholic Fatty Liver Disease
反复呈现视觉威胁会驱动先天性恐惧习惯化，并受环境和生理因素的调节。	Carroll, J. N.	PDF	N/A	Repeated presentation of visual threats drives innate fear habituation and is modulated by environmental and physiological factors
mRNA中下游结构元件对核糖体亚基间旋转动力学的影响	Shebl, B.	PDF	N/A	The influence of downstream structured elements within mRNA on the dynamics of intersubunit rotation in ribosomes
粗粒度动态模拟细胞骨架微管扭曲	Zhu, R.	PDF	N/A	Coarse-Grained Dynamic Simulation of Cytoskeletal Microtubule Twist
茉莉酸信号和谷胱甘肽协同调控植物从强光胁迫中恢复	Kilic, M.	PDF	N/A	Jasmonic acid signaling and glutathione coordinate plant recovery from high light stress
HEADING DATE 1基因突变对水稻转录及细胞壁组成的影响	Biancucci, M.	PDF	N/A	Impact of mutations in the HEADING DATE 1 gene on transcription and cell wall composition of rice
通过解决GPT不准确响应和基准测试上下文来创建生物医学知识库	Darnell, S. S.	PDF	N/A	Creating a biomedical knowledge base by addressing GPT inaccurate responses and benchmarking context
大肠杆菌的磷酸丙糖异构酶（TpiA）的结构可塑性	Calles, B.	PDF	N/A	The structural permissiveness of triosephosphate isomerase (TpiA) of Escherichia coli
大肠杆菌在接近致死酸胁迫下的集体生长动态	Segura Munoz, R. R.	PDF	N/A	Collective dynamics of Escherichia coli growth under near-lethal acid stress
在长期定殖过程中肠球菌物种间的异质性和代谢多样性	Karlsson, P. A.	PDF	N/A	Heterogeneity and Metabolic Diversity among Enterococcus Species during Long-term Colonization
丝裂霉素C与低剂量甲硝唑联合使用对艰难梭菌感染及其复发具有协同作用	Gong, J.-J.	PDF	N/A	Combination of mitomycin C and low-dose metronidazole synergistically against Clostridioides difficile infection and recurrence prevention
马拉色菌（Malassezia furfur）在替代模型宿主秀丽隐杆线虫（Caenorhabditis elegans）中的致病性和肠道屏障破坏能力，部分被鼠李糖乳杆菌（Lacticaseibacillus rhamnosus）所缓解。	Kishida, C.	PDF	N/A	Pathogenicity and intestinal barrier disruptive ability of Malassezia furfur in an alternative model host Caenorhabditis elegans is partially alleviated by Lacticaseibacillus rhamnosus
通过多聚C结合蛋白实现的铁敏感性RNA调控	Forbes, K.	PDF	N/A	Iron-sensitive RNA regulation by poly C binding proteins
自闭症患者血液中RNA/DNA杂交谱的分析揭示了mRNA和非编码RNA区域的差异	Kianmehr, L.	PDF	N/A	Analysis of RNA/DNA Hybrid Profiles in Blood From Autistic Patients Reveals Differences in mRNA and non-coding RNA Regions
囊性纤维化跨膜传导调节因子（CFTR）调节剂对血液蛋白质组的系统性影响	Fentker, K.	PDF	N/A	Systemic effects of cystic fibrosis transmembrane conductance regulator (CFTR) modulators on the blood proteome
核糖体相关质量控制因子TCF25通过结合并特异性地定向受体泛素，使得Listerin介导的新生链泛素化具有K48特异性。	Abaeva, I. S.	PDF	N/A	The ribosome-associated quality control factor TCF25 imposes K48 specificity on Listerin-mediated ubiquitination of nascent chains by binding and specifically orienting the acceptor ubiquitin
通过胆绿素还原酶敲除实现的先进深层组织成像与操控。	Kasatkina, L.	PDF	N/A	Advanced deep-tissue imaging and manipulation enabled by biliverdin reductase knockout.
结合环境微生物选择的微生物群落进化模型	Xiao, Y.	PDF	N/A	Models of microbiome evolution incorporating environmental microbial selection
神经元分化过程中依赖于上下文的表观基因组重编程	Manelli, V.	PDF	N/A	Context-dependent epigenome rewiring during neuronal differentiation
栽培柑橘的超泛基因组揭示了它们在网状进化异域分化阶段的演化特征	Droc, G.	PDF	N/A	A super-pangenome for cultivated citrus reveals evolutive features during the allopatric phase of their reticulate evolution
通过两种GTPase因子EngA和ObgE介导的单步体外核糖体重构	Sato, A.	PDF	N/A	Single-step in vitro ribosome reconstitution mediated by two GTPase factors, EngA and ObgE
赖氨酸特异性肽酶的比较分析，以优化蛋白质组学工作流程	van der Hoeven, L. R.	PDF	N/A	Comparative Analysis of Lysine-Specific Peptidases for Optimizing Proteomics Workflows
OfWRKY33结合关键的芳樟醇合酶基因OfTPS7，促进桂花中芳樟醇的合成	Xi, W.	PDF	N/A	OfWRKY33 binds to the key linalool synthase gene OfTPS7 to promote linalool synthesis in Osmanthus fragrans flowers
DNA依赖性蛋白激酶抑制剂PI-103和Samotolisib增强CRISPR/Cas9在人T细胞中的敲入效率	Dzafo, E.	PDF	N/A	DNA-Dependent Protein Kinase Inhibitors PI-103 and Samotolisib Augment CRISPR/Cas9 Knockin Efficiency in Human T Cells
# BioRxiv 2024-10-17 Papers

标题	作者	PDF链接	代码仓库	Title
杂合优势可以解释免疫基因的非凡多样性。	Siljestam, M.	PDF	N/A	Heterozygote advantage can explain the extraordinary diversity of immune genes
细菌中对多种药物产生耐药性的快速进化，且不依赖于SOS系统	Zhang, L.	PDF	N/A	Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria
网络的自然史：在地理历史数据中建模高阶相互作用	Rojas, A.	PDF	N/A	A natural history of networks: Modeling higher-order interactions in geohistorical data
多组学方法揭示RNA动态促进细胞对DNA低甲基化的敏感性	Ge, A. Y.	PDF	N/A	A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation
同时可视化单细胞RNA测序研究中的细胞及其标记基因	Bhattacharya, N.	PDF	N/A	Simultaneous visualization of cells and marker genes from scRNA-seq studies
BIBSNet：一种用于MRI扫描的深度学习婴儿图像脑部分割网络	Hendrickson, T. J.	PDF	N/A	BIBSNet: A Deep Learning Baby Image Brain Segmentation Network for MRI Scans
目标检测调节成功记忆编码的脑电图频谱相关性	Broitman, A. W.	PDF	N/A	Target Detection Modulates EEG Spectral Correlates of Successful Memory Encoding
基于血液的纳米定量免疫复合物检测：在诊断为帕金森病的患者中，对抑制剂耐药的种子活性检测	Christenson, P. R.	PDF	N/A	Blood-based Nano-QuIC: Inhibitor-resistant Detection of Seeding Activity in Patients Diagnosed with Parkinson Disease
逆转录转座子和卫星DNA的周转驱动了果蝇在短期进化时间尺度上的着丝粒重构	Courret, C.	PDF	N/A	Turnover of retroelements and satellite DNA drives centromere reorganizationover short evolutionary timescales in Drosophila
桥粒突变影响肿瘤微环境以促进黑色素瘤增殖	Baron, M.	PDF	N/A	Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation
LMD: 单细胞RNA-seq数据中独立于集群的多尺度标记识别	Li, R.	PDF	N/A	LMD: Cluster-Independent Multiscale Marker Identification in Single-cell RNA-seq Data
一个用于非平衡自组装和分枝肌动蛋白网络中力形态权衡的热力学框架	Rennert, E.	PDF	N/A	A thermodynamic framework for nonequilibrium self-assembly and force morphology tradeoffs in branched actin networks
算法代理中的结构化动态	Ruffini, G.	PDF	N/A	Structured dynamics in the algorithmic agent
视觉皮层中细胞类型与视觉依赖性转录程序相互作用的时空分析	Xie, F.	PDF	N/A	Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex
最小顶点模型解释了果蝇背部闭合过程中羊膜细胞如何避免液化。	Tah, I.	PDF	N/A	Minimal vertex model explains how the amnioserosa avoids fluidization during Drosophila dorsal closure
U/V性染色体系统中性分化的发育途径	Liesner, D.	PDF	N/A	Developmental pathways underlying sexual differentiation in a U/V sex chromosome system
神经代码追踪叙事中的先前事件，并预测后续对细节的记忆。	Collin, S. H. P.	PDF	N/A	Neural codes track prior events in a narrative and predict subsequent memory for details
基于模型的前臂肌肉在2自由度手腕任务中使用MRE估计主动和被动肌肉力的方法	Helm, C. A.	PDF	N/A	Model-Based Estimation of Active and Passive Muscle Forces Using MRE in Forearm Muscles During 2-DOF Wrist Tasks
查尔酮和吡唑啉衍生物的合成及其作为ELF3-MED23相互作用新型抑制剂的生物学评估	Hwang, S.-Y.	PDF	N/A	Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction
多重检测人类疾病相关突变揭示了UTR二核苷酸组成作为RNA稳定性的主要决定因素	Su, J.-Y.	PDF	N/A	Multiplexed Assays of Human Disease-relevant Mutations Reveal UTR Dinucleotide Composition as a Major Determinant of RNA Stability
基于压缩感知的方法识别驱动习得病原体回避的模块化神经回路	Hallacy, T.	PDF	N/A	Compressed sensing based approach identifies modular neural circuitry driving learned pathogen avoidance
在77K下测量的叶片中从PSII到PSI的激发溢出	Terashima, I.	PDF	N/A	Excitation Spillover from PSII to PSI Measured in Leaves at 77K
依赖于小泛素样修饰物（SON）的核斑点再生能够缓解蛋白质病	Dion, W.	PDF	N/A	SON-dependent nuclear speckle rejuvenation alleviates proteinopathies
年轻小鼠的微生物群通过调节老年小鼠的丁酸水平，对抗了与年龄相关的痛风易感性。	Song, N.	PDF	N/A	Microbiota from young mice counteracts susceptibility to age-related gout through modulating butyric acid levels in aged mice
高加索侏儒鰕虎鱼（Knipowitschia cf. caucasica）染色体水平基因组参考，这是一种新入侵莱茵河的鰕虎鱼科外来物种	Schoenle, A.	PDF	N/A	Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine
改变沙眼衣原体的氧化还原状态会直接影响其发育周期的进展。	Singh, V.	PDF	N/A	Altering the redox status of Chlamydia trachomatis directly impacts its developmental cycle progression
对鼠伤寒沙门氏菌基因组抗菌药物耐药性流行病学的剖析	Kaur, S.	PDF	N/A	A dissection of the genomic antimicrobial resistance epidemiology of Salmonella Typhimurium
NHR-23调控的假定蛋白酶抑制剂mlt-11基因对于秀丽隐杆线虫（C. elegans）的表皮结构和功能是必需的。	Ragle, J. M.	PDF	N/A	The NHR-23-regulated putative protease inhibitor mlt-11 gene is necessary for C. elegans cuticle structure and function
利用Sentence-BERT从预测数据库中精炼疾病相关蛋白质水平的微RNA靶点相互作用	Chen, B.	PDF	N/A	Refining Protein-Level MicroRNA Target Interactions in Disease from Prediction Databases Using Sentence-BERT
PVD神经元在秀丽隐杆线虫中具有雄性特异性结构和交配功能。	Iosilevskii, Y.	PDF	N/A	The PVD neuron has male-specific structure and mating function in C. elegans
HIV-1感染与生发中心B细胞的耗竭以及胃肠道中IgA+浆细胞的减少有关。	Cossarini, F.	PDF	N/A	HIV-1 infection is associated with depletion of germinal center B cells and a decrease in IgA+ plasma cells in the GI tract
环二腺苷酸推动沙眼衣原体发育周期的进展	Lee, J.	PDF	N/A	Cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis
多物理场模拟揭示了患者来源的左心房组织力学中与纤维化相关的变化对血流动力学的影响	Gonzalo, A.	PDF	N/A	Multi-physics simulations reveal hemodynamic impacts of patient-derived fibrosis-related changes in left atrial tissue mechanics
累积的储备阻碍了与年龄相关的噪音中言语感知中的神经补偿	Zhang, L.	PDF	N/A	Accumulated reserves hold back age-related neural compensation in speech-in-noise perception
ProtEx：一种用于蛋白质功能预测的检索增强方法	Shaw, P.	PDF	N/A	ProtEx: A Retrieval-Augmented Approach for Protein Function Prediction
使用语言模型进行蛋白质序列域注释	Sarkar, A.	PDF	N/A	Protein Sequence Domain Annotation using Language Models
Gap-App：一种基于性别的AI胰腺导管腺癌生存预测器，作为面向患者和医生的网络应用程序开放	Ojha, A.	PDF	N/A	Gap-App: A sex-distinct AI-based predictor for pancreatic ductal adenocarcinoma survival as a web application open to patients and physicians
使用键合图对单个肌动蛋白丝聚合进行基于能量的建模	Gawthrop, P.	PDF	N/A	Energy-based Modelling of Single Actin Filament Polymerisation Using Bond Graphs
黑色素化与土壤矿物和微生物特性相互作用，共同决定土壤中真菌碳和氮的持久性。	Beidler, K. V.	PDF	N/A	Melanization interacts with soil mineral and microbial properties to determine fungal carbon and nitrogen persistence in soils
分层种群遗传结构和适应性特征在尖吻鲈（Lates calcarifer）中的体现	Campbell, M. A.	PDF	N/A	Hierarchical population genetic structure and signatures of adaptation in Lates calcarifer
翼龙尾巴羽片的新软组织数据显示了其复杂、动态的张力使用方式，并扩展了其进化起源。	Jagielska, N.	PDF	N/A	New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins
I2Bot：一种用于昆虫导航的多模态和具身模拟的开源工具	Sun, X.	PDF	N/A	I2Bot: an open-source tool for multi-modal and embodied simulation of insect navigation
基于石墨烯的微电极，具有增强的界面和可调的孔隙结构，用于提高神经记录效果	Dong, M.	PDF	N/A	Graphene-based micro-electrodes with reinforced interfaces and tunable porous structures for improved neural recordings
Xist RNA结合特定的常染色体基因，并依赖于重复序列B来调控这些基因的表达。	Yao, S.	PDF	N/A	Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression
硫醚功能化纤维素用于制备氧化响应性生物材料涂层和薄膜	DuBois, E. M.	PDF	N/A	Thioether-functionalized cellulose for the fabrication of oxidation-responsive biomaterial coatings and films
爱荷华脑行为建模工具包：一个用于成像-行为和损伤-缺陷关系推断与预测建模的开源MATLAB工具	Griffis, J. C.	PDF	N/A	Iowa Brain-Behavior Modeling Toolkit: An Open-Source MATLAB Tool for Inferential and Predictive Modeling of Imaging-Behavior and Lesion-Deficit Relationships
一类新的受体：脂质通过其膜锚定物调节哺乳动物Gsα刺激的腺苷酸环化酶活性	Landau, M.	PDF	N/A	A new class of receptors: Lipids regulate mammalian Gsα-stimulated adenylyl cyclase activities via their membrane anchors
百日咳博德特氏菌疫苗反应中的Th1极化通过正反馈回路得以维持。	Willemsen, L.	PDF	N/A	Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop
不同表型水稻干旱和盐胁迫公共RNA测序数据的Meta分析	Shintani, M.	PDF	N/A	Meta-analysis of public RNA-sequencing Data of Drought and Salt Stresses in Different Phenotypes of Oryza sativa
使用扩散模型生成P型ATP酶的多状态构象	Xu, J.	PDF	N/A	Generating Multi-state Conformations of P-type ATPases with a Diffusion Model
生物分子凝聚体在相分离的质量守恒反应扩散系统实验与理论之间架起了桥梁。	Li, C.	PDF	N/A	Biomolecular condensates bridge experiment and theory of mass-conserving reaction-diffusion systems in phase separation
领地性和资源可用性调节同种个体相遇对哺乳动物捕食者觅食行为的影响	Clermont, J.	PDF	N/A	Territoriality and resource availability modulate the effect of conspecific encounters on the foraging behaviours of a mammalian predator
VP35中隐秘口袋的打开和关闭使其在两种不同的RNA结合模式之间切换。	Mallimadugula, U. L.	PDF	N/A	Opening and closing of a cryptic pocket in VP35 toggles it between two different RNA-binding modes
开发日本柳杉D. Don中雄性不育4 (MS4)基因的简易DNA提取和PCR-RFLP方法：迈向环境友好型协议	Ueno, S.	PDF	N/A	Developing simple DNA extraction and PCR-RFLP for MALE STERILITY 4 (MS4) gene in Cryptomeria japonica D. Don: Toward an environmentally friendly protocol
RNA在α-突触核蛋白相分离的纳米尺度组织中的作用	Zappone, S.	PDF	N/A	The role of RNA in the nanoscale organization of alpha-synuclein phase separation
多发性硬化症中克隆扩增的CD8+ T细胞的抗原特异性	Mittl, K.	PDF	N/A	Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis
通过双向循环门控建模大脑中的注意力和绑定机制	Salehinajafabadi, S.	PDF	N/A	Modeling Attention and Binding in the Brain through Bidirectional Recurrent Gating
致癌驱动突变N642H在STAT5B SH2结构域中的结构影响	Haas-Neill, L.	PDF	N/A	The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain
基于角色共享的协同群体行为分析：从实验任务到3对3篮球比赛的实际应用作为试点研究	Ichikawa, J.	PDF	N/A	Analysis of coordinated group behavior based on role-sharing: Practical application from an experimental task to a 3-on-3 basketball game as a pilot study
在小鼠齿状回中，5-HT7受体的激活并不影响穿通路径突触处的θ波爆发诱导的可塑性。	Siwiec, M.	PDF	N/A	Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse
在小鼠齿状回中，5-HT7受体的激活并不影响穿通路径突触处的theta波簇诱导的可塑性。	Siwiec, M.	PDF	N/A	Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse
模仿机制：肉类与肉类替代品的比较	St. Pierre, S. R.	PDF	N/A	Mimicking mechanics: A comparison of meat and meat analogs
外膜变化使细菌能够逃避捕食	Mridha, S.	PDF	N/A	Outer membrane changes enable evolutionary escape from bacterial predation
stFormer：一种用于空间转录组学的基石模型	Cao, S.	PDF	N/A	stFormer: a foundation model for spatial transcriptomics
细菌的运动模式能够顺利适应空间限制和紊乱的变化	Zhang, H.	PDF	N/A	Bacterial motility patterns adapt smoothly in response to spatial confinement and disorder
神经运动生成的空间和网络原理	Komi, S.	PDF	N/A	Spatial and network principles behind neural generation of locomotion
James-Stein估计器提高了人体运动学和代谢数据中的准确性和样本效率。	Alwan, A.	PDF	N/A	James-Stein estimator improves accuracy and sample efficiency in human kinematic and metabolic data
一种非典型的E3连接酶在营养应激期间保护核糖体	Douglas, T.	PDF	N/A	An atypical E3 ligase safeguards the ribosome during nutrient stress
计算微生物组药理学分析阐明阴道微生物及其代谢物的抗癌潜力	Lawore, D. C.	PDF	N/A	Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites
腹侧纹状体与凸显网络具有特别密切的关联，该网络包括背外侧前额叶皮层中的区域。	Kosakowski, H. L.	PDF	N/A	Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex
从生物物理模型和保存的标本中可靠地重建蟋蟀鸣声	Weiner, R. J.	PDF	N/A	Reliable reconstruction of cricket song from biophysical models and preserved specimens
多成分营养补充剂与衰老干预在老年小鼠中具有可比的抗衰老功效	Brookes, C.	PDF	N/A	Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice
两种亚麻品种的比较分析表明，木脂素介导的盐胁迫适应性	Debnath, A. J.	PDF	N/A	A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness
用于酶学表征菱形蛋白酶RHBDL4的体外平台	Bhaduri, S. E.	PDF	N/A	An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4
半监督组学因子分析（SOFA）在多组学数据中将已知的变异源与潜在因子解耦。	Capraz, T.	PDF	N/A	Semi-supervised Omics Factor Analysis (SOFA) disentangles known sources of variation from latent factors in multi-omics data
用于预测血脑屏障渗透性的注意力图神经网络模型	Collins, J. W.	PDF	N/A	Attentive graph neural network models for the prediction of blood-brain barrier permeability
用于预测血脑屏障渗透性的注意力图神经网络模型	Collins, J. W.	PDF	N/A	Attentive graph neural network models for the prediction of blood-brain barrier permeability
Asgard古菌对真核生物起源的显著贡献	Tobiasson, V.	PDF	N/A	Dominant contribution of Asgard archaea to eukaryogenesis
通过整合多层次事件时间概率分布进行时间预测	Huang, Y. T.	PDF	N/A	Temporal Prediction through Integration of Probability Distributions of Event Timings at Multiple Levels
多巴胺在执行动作序列期间奖励预期和可预测性中的作用	Magnard, R.	PDF	N/A	Role of dopamine in reward expectation and predictability during execution of action sequences
理解神经元多样性：输入动力学和选择性的作用	Joshi, N.	PDF	N/A	Understanding Neuronal Diversity: Role of Input Dynamics and Selectivity
在高级皮质网络中，阿尔法和贝塔节律中的时间延迟表征随着关系整合需求的增加而追踪。	Robinson, C. N.	PDF	N/A	Temporally delayed representations in alpha and beta rhythms in higher-order cortical networks track increasing relational integration demands
海马体中刺激意义的表征	Biane, J. S.	PDF	N/A	Representations of stimulus meaning in the hippocampus
活性氧物种的增加是新生儿小脑修复的基础	Pakula, A.	PDF	N/A	An increase in reactive oxygen species underlies neonatal cerebellum repair
准确而灵活的有效群体数量历史估计	Huang, Z.	PDF	N/A	Accurate and flexible estimation of effective population size history
SPLENDID 在生物银行规模的数据中整合了连续的遗传祖先信息，以提高不同人群的多基因风险预测能力。	Chen, T.	PDF	N/A	SPLENDID incorporates continuous genetic ancestry in biobank-scale data to improve polygenic risk prediction across diverse populations
KLHDC7B是一种与人类年龄相关性听力损失相关的新基因，对于维持小鼠的听力是必需的。	Kaufman, A. M.	PDF	N/A	KLHDC7B, a novel gene associated with age-related hearing loss in humans, is required for the maintenance of hearing in mice.
通过靶向3D基因组，利用蒽环类药物实现化疗效果	Tan, M.	PDF	N/A	Targeting the 3D genome by anthracyclines for chemotherapeutic effects
小脑在认知老化中的保护作用	d'Oleire Uquillas, F.	PDF	N/A	A protective role for the cerebellum in cognitive aging
前额叶协调：一种用于啮齿动物运动抑制的皮层网络	Jaeckel, Z.	PDF	N/A	Prefrontal orchestration: a cortical network for rodent motor inhibition
神经元的限制性N-糖基化在分化过程中被编程	Kiwimagi, K.	PDF	N/A	The restricted N-glycome of neurons is programmed during differentiation
综合应激反应通过维持线粒体输入效率来抑制依赖于PINK1的线粒体自噬	Yang, M.	PDF	N/A	The Integrated Stress Response Suppresses PINK1-dependent Mitophagy by Preserving Mitochondrial Import Efficiency
利用稳定同位素示踪法建模复合脂质稳态	Wessendorf-Rodriguez, K.	PDF	N/A	Modeling Compound Lipid Homeostasis Using Stable Isotope Tracing
GRASP55调控溶酶体酶β-氨基己糖苷酶A的分选与成熟	Akaaboune, S. R.	PDF	N/A	GRASP55 Regulates Sorting and Maturation of the Lysosomal Enzyme β-Hexosaminidase A
袖内运输同时利用了微管和肌动蛋白轨道。	Judernatz, J.	PDF	N/A	Intra-manchette transport employs both microtubule and actin tracks
BAK驱动的凋亡孔形成的脂质特征	Uren, R. T.	PDF	N/A	A lipid signature of BAK-driven apoptotic pore formation
全面鉴定质膜修复蛋白揭示了细胞对质膜损伤的时空响应	Yamazaki, Y.	PDF	N/A	Comprehensive identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage
β-肾上腺素能阻滞剂通过胰腺β细胞中的PKA/RYR2/TRPM5途径增加cAMP并刺激胰岛素分泌（体外实验）	Murao, N.	PDF	N/A	β-adrenergic blockers increase cAMP and stimulate insulin secretion through a PKA/RYR2/TRPM5 pathway in pancreatic β-cells in vitro
I类PAK在调节肌动蛋白细胞骨架兴奋性中的作用。	Tyler, J. J.	PDF	N/A	A role for class I PAKs in the regulation of the excitability of the actin cytoskeleton.
新型抗体可检测原生生物病原体、细胞黏菌和植物中的核内质O-岩藻糖	Tiwari, M.	PDF	N/A	Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants
自闭症中的白质微结构改变通过束分析定位	Kim, G. S.	PDF	N/A	White Matter Microstructural Alterations in Autism Localized with Bundle Analytics
对一种脆海星中荧光素酶的功能表征表明，平行进化受到卤代烷脱卤酶基因组可用性的影响。	Lau, E. S.	PDF	N/A	Functional characterization of luciferase in a brittle star indicates parallel evolution influenced by genomic availability of haloalkane dehalogenase
光照在弱电鱼的活动感知和控制中起到中介作用，促使两者发生转变。	Yeh, H.	PDF	N/A	Illumination mediates a switch in both active sensing and control in weakly electric fish
在“通过网络推断和计算机模拟基因扰动剖析细胞身份”中发现的重大问题	Nourisa, J.	PDF	N/A	Critical issues found in "Dissecting cell identity via network inference and in silico gene perturbation"
淡水螺类Physa acuta中，同代与跨代捕食者诱导可塑性的转录组基础	Dejeux, L.	PDF	N/A	Transcriptomic bases of within- and trans-generational predator-induced plasticity in the freshwater snail Physa acuta
集成机器学习在代谢组数据中的应用：识别与巨噬细胞极化相关的代谢物	Gannavaram, A.	PDF	N/A	Application of Ensemble Machine Learning to Metabolomic Data Identifies Metabolites Associated with Macrophage Polarization
囊杆菌素脱靶分析揭示了其在真核生物中具有良好的安全性、超氧化物还原能力以及SCARB1抑制作用	Risch, T.	PDF	N/A	Cystobactamid off-target profiling reveals favorable safety, superoxide reduction, and SCARB1 inhibition in eukaryotes
三种细胞色素P450酶在鼠尾草属植物中催化形成呋喃克罗烷前体。	Lin, R.	PDF	N/A	Three cytochrome P450 enzymes catalyse the formation of furanoclerodane precursors in Salvia spp.
对来自芬兰的首个巨型病毒Jyväskylä病毒的基因组和结构深入研究	de Freitas Almeida, G. M.	PDF	N/A	Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland
高糖食物会加剧抗生素引起的微生物群损伤。	Dai, A.	PDF	N/A	Sugar-rich foods exacerbate antibiotic-induced microbiome injury
丝裂霉素C在金黄色葡萄球菌适应性实验室进化后仍保持疗效	Petersen, M. E.	PDF	N/A	Mitomycin C Retains Efficacy after Adaptive Laboratory Evolution of Staphylococcus aureus
小分子激活TFEB通过促进溶酶体胞吐作用和生物发生缓解尼曼-皮克病C型	Du, K.	PDF	N/A	Small-molecule Activation of TFEB Alleviates Niemann-Pick Disease Type C via Promoting Lysosomal Exocytosis and Biogenesis
有丝分裂纺锤体的定向和动态变化通过NuMA定位在各向异性组织拉伸的作用下得到了精细调节。	Tarannum, N.	PDF	N/A	Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tissue stretch via NuMA localisation
TRIM蛋白家族中RING E3假性联酶的鉴定	Dudley-Fraser, J.	PDF	N/A	Identification of RING E3 pseudoligases in the TRIM protein family
Nrf2 调控表观遗传学调节，并在砷诱导的转化过程中作为 KLF4 表达和活性的主调控因子。	Wang, Z.	PDF	N/A	Nrf2 orchestrates epigenetic regulations and serves as the master regulator of KLF4 expression and activity during arsenic-induced transformation
复制白细胞介素-15超级激动剂的逆转录病毒传递，可增强抗肿瘤免疫并提高低免疫原性胶质母细胞瘤模型中的长期生存率	Haddad, A. F.	PDF	N/A	Replicating retroviral delivery of an IL-15 superagonist improves antitumor immunity and long-term survival in poorly immunogenic glioblastoma models
复制白细胞介素-15超级激动剂的逆转录病毒传递方式可增强抗肿瘤免疫并提高低免疫原性胶质母细胞瘤模型的长期生存率	Haddad, A. F.	PDF	N/A	Replicating retroviral delivery of an IL-15 superagonist improves antitumor immunity and long-term survival in poorly immunogenic glioblastoma models
DDX41通过溶解G-四链体来维持红细胞基因组的完整性，并防止cGAS介导的细胞死亡。	Bi, H.	PDF	N/A	DDX41 dissolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death
芸薹属植物（Brassica campestris L. ssp. chinensis）中生长调节因子BRAGRF5的分子特征及启动子元件分析	Wang, X.-Y.	PDF	N/A	MOLECULAR CHARACTERIZATION AND PROMOTER ELEMENT ANALYSIS OF GROWTH REGULATOR BRAGRF5 IN BRASSICA CAMPESTRIS L. SSP. CHINENSIS
脱脂辣木籽的生化和植物化学功效在对抗营养不良中的作用	Jegede, R. E.	PDF	N/A	Biochemical and Phytochemical Efficacy of Defatted Moringa oleifera Seeds in combating Malnutrition
褐藻门三角褐指藻Seipin同源蛋白的功能研究突显了硅藻脂滴生物发生的独特特征。	Le Moigne, D.	PDF	N/A	Functional study of Phaeodactylum tricornutum Seipin homolog highlights unique features of lipid droplets biogenesis in diatoms.
OpenASO：RNA救援——通过社区科学设计剪接调节反义寡核苷酸	Tse, V.	PDF	N/A	OpenASO: RNA Rescue--designing splice-modulating antisense oligonucleotides through community science
耗竭的贩运调节因子CASK促进间插盘组织和心室功能	Blandin, C. E.	PDF	N/A	Depleting trafficking regulator CASK promotes intercalated disc organization and ventricular function
AAA-ATP酶Cdc48p在过氧化物酶体质量控制中的作用	Yusuf, I. F.	PDF	N/A	Role of AAA-ATPase Cdc48p in Peroxisomal Quality Control
使用结构化溯祖模型进行病原体系统地理学贝叶斯推断	Roberts, I.	PDF	N/A	Bayesian Inference of Pathogen Phylogeography using the Structured Coalescent Model
微生物组如何从血红素中释放铁	Nath, A. K.	PDF	N/A	How the microbiome liberates iron from heme
一项全面的工程策略提升了针对HIV的近泛中和抗体的效力和生产可行性	Sajadi, M.	PDF	N/A	A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV
通过综合19F-NMR技术比较了人源GPCR在脂质囊泡和水溶液中的构象平衡	Ray, A.	PDF	N/A	The conformational equilibria of a human GPCR compared between lipid vesicles and aqueous solutions by integrative 19F-NMR
将阿托摩尔级检测带至即时护理点：基于纳米图案DNA折纸的纳米天线技术	Yaadav, R.	PDF	N/A	Bringing Attomolar Detection to the Point-of-Care with Nanopatterned DNA Origami Nanoantennas
高表达的细胞壁基因有助于花萼大小的稳定性	Hartasanchez, D. A.	PDF	N/A	Highly expressed cell wall genes contribute to robustness of sepal size
代谢相互作用驱动交叉喂养微生物群落中的种群周期	Ross, T.	PDF	N/A	Metabolic interplay drives population cycles in a cross-feeding microbial community
热带海鸟（Sula）在加利福尼亚洋流生态系统中数量增加，与海洋变暖条件相关	Russell, T. M.	PDF	N/A	Increase of tropical seabirds (Sula) in the California Current Ecosystem with warmer ocean conditions
台湾精准医疗计划：大规模研究队列	Yang, H.-C.	PDF	N/A	The Taiwan Precision Medicine Initiative: A Cohort for Large-Scale Studies
人类脑组织中RNA质量指标的分析	Tian, J.	PDF	N/A	An analysis of RNA quality metrics in human brain tissue
靶向质谱法揭示了啮齿动物多囊卵巢综合征模型中激素和生物活性脂质血浆谱的改变	Scott, H. C.	PDF	N/A	Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
在肌肉糖原含量降低的情况下进行耐力运动会影响底物利用，并减弱人类I型和II型肌纤维中的急性mTORC1信号和自噬信号。	Horwath, O.	PDF	N/A	Endurance exercise with reduced muscle glycogen content influences substrate utilization and attenuates acute mTORC1- and autophagic signaling in human type I and type II muscle fibers
早期生命病毒组研究中的负样本：特征与去污染	Kuzub, N.	PDF	N/A	Negativeome in Early-Life Virome Studies: Characterization and Decontamination
微空间尺度下土壤微节肢动物群落构建——一项微宇宙操控研究	Dirilgen, T.	PDF	N/A	Soil microarthropod community assembly at the micro spatial scale - A microcosm manipulation study
Dexrazoxane作为冈比亚按蚊中可行的微孢子虫控制剂	Zeferino, T. G.	PDF	N/A	Dexrazoxane as a viable microsporidia control agent in Anopheles gambiae
未来气候下褐藻（Ascophyllum nodosum）的热应激：不同种群的敏感性差异。	Pereira, L. F.	PDF	N/A	Heat Stress on the brown Seaweed Ascophyllum nodosum: differential population sensitivity to future climate.
PARMIK：基于廉价K-mer的部分读取匹配	Baradaran, M.	PDF	N/A	PARMIK: PArtial Read Matching with Inexpensive K-mers
转录过程中RNA折叠中间体的顺序结构探测	Szyjka, C. E.	PDF	N/A	Sequential structure probing of cotranscriptional RNA folding intermediates
一种高保真的人类DNA聚合酶全酶具有广泛的损伤旁路活性。	Dannenberg, R. L.	PDF	N/A	A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities
模拟悬浮细胞的三维折射率分布	Borrelli, F.	PDF	N/A	Simulating 3D refractive index distributions of suspended cells
阴离子脂质对阴离子交换蛋白1（AE1）构象转变能量景观的影响	Chen, T.	PDF	N/A	Impact of anionic lipids on the energy landscape of conformational transition in anion exchanger 1 (AE1)
扭转是DNA复制停滞和重新激活的动态调节器	Jia, X.	PDF	N/A	Torsion is a Dynamic Regulator of DNA Replication Stalling and Reactivation
表达GRK2氨基末端肽转基因小鼠中的女性特异性限制性心肌病与代谢紊乱	Bledzka, K. M.	PDF	N/A	Female Specific Restrictive Cardiomyopathy and Metabolic Dysregulation in transgenic mice expressing a Peptide of the Amino-Terminus of GRK2
DD基因组的整合重塑了异源六倍体小麦的基因转录、染色质结构和代谢组，从而增强了其适应性。	Liu, Y.	PDF	N/A	Integration of the DD-genome reshapes gene transcription, chromatin architecture and metabolome of allohexaploid wheat leading to enhanced adaptability
Aβ靶向的synNotch受体用于阿尔茨海默病：扩展应用至胞外蛋白聚集体	Bergo, N. J.	PDF	N/A	Aβ-targeting synNotch Receptor for Alzheimer's Disease: Expanding Applications to Extracellular Protein Aggregates
STRAIGHT-IN 双载体系统：一种用于将DNA有效载荷和基因电路双拷贝、单拷贝整合到人类诱导多能干细胞中的平台	Blanch Asensio, A.	PDF	N/A	STRAIGHT-IN Dual: a platform for dual, single-copyintegrations of DNA payloads and gene circuits into human induced pluripotent stem cells
鸡盲肠中微生物群落的代谢建模揭示了竞争与合作并存的格局	Utkina, I.	PDF	N/A	Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation
转录组增强的水稻籽粒代谢模型识别出组氨酸水平作为籽粒粉质度的标志	Chowdhury, N. B.	PDF	N/A	Transcriptome Enhanced Rice Grain Metabolic Model Identifies Histidine Level as a Marker for Grain Chalkiness
马凡综合征雌性小鼠的皮质神经元中凋亡增加。	Esfandiarei, M.	PDF	N/A	Apoptosis is increased in cortical neurons of female Marfan Syndrome mice
解开焦虑、自闭和精神病特质对感知推断的影响	Bevalot, C.	PDF	N/A	Disentangling the effects of Anxious, Autistic and Psychotic Traits on Perceptual Inference
使用超高分辨率全脑扩散MRI直接分割皮层细胞构筑域	Pas, K. E.	PDF	N/A	Direct segmentation of cortical cytoarchitectonic domains using ultra-high-resolution whole-brain diffusion MRI
背景光流会调节多个下行中间神经元对蝗虫中物体运动的反应	Zhang, S.	PDF	N/A	Background optic flow modulates responses of multiple descending interneurons to object motion in locusts
敲除与LRRK2对抗的RAB磷酸酶PPM1H会破坏轴突自噬并加剧α-突触核蛋白的聚集	Fricke, M.	PDF	N/A	Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
m6A介导的表观转录组失调是脆性X综合征中突触功能障碍的基础	Guo, Z.	PDF	N/A	m6A-mediated epi-transcriptomic dysregulation underlies synaptic dysfunction in fragile X syndrome
血管周围和实质液体的特征与整个生命周期中的年龄和认知表现有关。	Lynch, K. M.	PDF	N/A	Perivascular and parenchymal fluid characteristics are related to age and cognitive performance across the lifespan
Pep2Vec：一种用于肽-MHC呈递预测和配体组数据集中污染物鉴定的可解释模型	Thrift, W. J.	PDF	N/A	Pep2Vec: An Interpretable Model for Peptide-MHC Presentation Prediction and Contaminant Identification in Ligandome Datasets
从重组蛋白自发形成不同形式的α-突触核蛋白纤维	Egorov, V. V.	PDF	N/A	Spontaneous formation of different forms of alpha-synuclein fibrils from a recombinant protein
微生物iCLIP2：通过促进蛋白质和RNA的稳定性增强RNA-蛋白质相互作用的映射	Stoffel, N. K.	PDF	N/A	Microbial iCLIP2: Enhanced mapping of RNA-Protein interaction by promoting protein and RNA stability
BMP-9和BMP-10中链间二硫键形成的分子基础	Schwartze, T. A.	PDF	N/A	Molecular basis of interchain disulfide-bond formation in BMP-9 and BMP-10
拯救迪纳拉山猫：多学科监测与利益相关者参与助力大型食肉动物在人类主导景观中的恢复	Krofel, M.	PDF	N/A	Saving the Dinaric lynx: multidisciplinary monitoring and stakeholder engagement support large carnivore restoration in human-dominated landscape
加利福尼亚岩质潮间带的一个包含寄生生物的食物网	Zilz, Z. L.	PDF	N/A	A parasite-inclusive food web for the California rocky intertidal zone
评估植物-微生物群落在应对环境胁迫下的相互作用，以增强盐沼恢复效果	Davis, K. A.	PDF	N/A	Evaluating Plant-Microbe Associations in Response to Environmental Stressors to Enhance Salt Marsh Restoration
保护区是否在追踪对陆地生物多样性的威胁？	Pulido Chadid, K.	PDF	N/A	Are protected areas tracking threats to terrestrial biodiversity?
基于谱系的丙型肝炎病毒宿主内动态演化分析	Zhao, L.	PDF	N/A	Lineage-aware evolutionary analysis of hepatitis C virus within-host dynamics
ISWI染色质重塑因子SMARCA5对哺乳动物减数分裂基因表达和雄性生育力至关重要	Kataruka, S.	PDF	N/A	ISWI chromatin remodeler SMARCA5 is essential for meiotic gene expression and male fertility in mammals
基准贝叶斯共定位方法在验证基于孟德尔随机化的循环蛋白质对心血管代谢疾病目标发现中的应用	Zhang, W.	PDF	N/A	Benchmarking Bayesian colocalization methods in validating Mendelian randomization-based target discoveries from circulating proteins for cardiometabolic diseases
人类海马体衰老过程中的表观遗传与三维基因组重编程	Zemke, N.	PDF	N/A	Epigenetic and 3D genome reprogramming during the aging of human hippocampus
从南设得兰群岛（南极洲）采集的巨藻鸥（Larus dominicanus）粪便中检测到德尔塔冠状病毒及其他鸟类相关病毒，并进行了全基因组测序。	Gomes, F.	PDF	N/A	Detection and full genome sequencing of a Deltacoronavirus and other bird associated viruses from feces of the kelp gull (Larus dominicanus) sampled at the South Shetland Islands Antarctica.
疾病结肠组织中的eQTL鉴定出与IBD相关的新靶基因	Nishiyama, N. C.	PDF	N/A	eQTL in diseased colon tissue identifies novel target genes associated with IBD
从动物行为和福利的角度来看，监狱犬类训练计划的效果如何？	Baria-Unwalla, P.	PDF	N/A	What's in it for the dogs? Assessing the outcomes of a prison-based dog training program from an animal behavior and welfare perspective
端到端多模态深度学习用于实时解码来自同一细胞的数月长神经活动	He, Y.	PDF	N/A	End-to-end multimodal deep learning for real-time decoding of months-long neural activity from the same cells
合成与表征氯喹修饰的白蛋白结合siRNA-脂质偶联物，以提高癌细胞内的递送效率和基因沉默效果	Lo, J. H.	PDF	N/A	Synthesis and characterization of chloroquine-modified albumin-binding siRNA-lipid conjugates for improved intracellular delivery and gene silencing in cancer cells
特定领域人工智能对小鼠胚胎干细胞中IMPDH2杆/环结构的分割	Ball, S. T. M.	PDF	N/A	Domain Specific AI Segmentation of IMPDH2 Rod/Ring Structures in Mouse Embryonic Stem Cells
肺炎克雷伯菌株在白蚁、黑猩猩和人类之间的循环	Houmenou, C. T.	PDF	N/A	Circulation of Klebsiella pneumoniae strains between the termites, chimpanzees and humans
微生物组数据分析的半合成模拟	Sankaran, K.	PDF	N/A	Semisynthetic Simulation for Microbiome Data Analysis
基于上下文的细菌基因组蛋白质功能预测	Toibazar, D.	PDF	N/A	Context-based protein function prediction in bacterial genomes
扩展和改进核苷酸重编码RNA-seq实验分析的EZbakR套件	Vock, I.	PDF	N/A	Expanding and improving analyses of nucleotide recoding RNA-seq experiments with the EZbakR suite
EGFR与酪氨酸激酶抑制剂相互作用的氢氘交换质谱（HDX-MS）研究	Ashtekar, K. D.	PDF	N/A	EGFR and tyrosine kinase inhibitor interactions probed by hydrogen-deuterium exchange and mass spectrometry (HDX-MS)
CDK4/6与PI3K抑制剂的新型组合在尤文肉瘤中展现出高度协同作用及转化潜力。	De Los Santos, M. A. I. C.	PDF	N/A	A novel combination of CDK4/6 and PI3K inhibitors exhibits highly synergistic activity and translational potential in Ewing sarcoma.
F(ab)'2片段相对于IgG在RIT和PRIT中的优势	Tabaja, Z. E.	PDF	N/A	Advantage of the F(ab)'2 fragment over IgG for RIT and PRIT
整合的人类骨骼肌单细胞功能蛋白质组学分析揭示了nemaline肌病中细胞特异性的转变	Seaborne, R. A. E.	PDF	N/A	Integrated single cell functional-proteomic profiling of human skeletal muscle reveals a shift in cellular specificity in nemaline myopathy
光呼吸的替代方案：系统级分析揭示了提高植物生产力的机制	Smith, E. N.	PDF	N/A	Alternatives to photorespiration: A systems-level analysis reveals mechanisms of enhanced plant productivity
利用昼夜节律钟调控的顺式调控突变，构成了自然选择下阿拉伯芥哈勒里极端性状的基础。	Castanedo, L.	PDF	N/A	Cis-regulatory mutations co-opting circadian clock regulation underlie naturally selected extreme trait in Arabidopsis halleri
溢出率并不能预测宿主跳跃的风险。	Simony, B. J.	PDF	N/A	Spillover rate is not predictive of host jump risk
一份详尽的蛋白质组和磷酸蛋白质组在不同小鼠组织和脑区中的周转图谱	Li, W.	PDF	N/A	An Extensive Atlas of Proteome and Phosphoproteome Turnover Across Mouse Tissues and Brain Regions
微生物产生的胆汁酸与纤维肌痛患者中高水平IgG自身抗体和较差的心理健康状况相关。	Jakobsson, J. E.	PDF	N/A	Microbially produced bile acids are associated with high levels of IgG autoantibodies and worse mental wellbeingin fibromyalgia subjects
空间频率通道介导了人类空间知觉的视觉度量	Zhang, S.	PDF	N/A	Spatial frequency channels mediate a visual metric for human spatial perception
时间泛化有界积累模型优于现有模型，并能捕捉模态差异和学习效应。	Ofir, N.	PDF	N/A	A bounded accumulation model of temporal generalization outperforms existing models and captures modality differences and learning effects
正念训练影响与青少年压力反应相关的大脑网络动态。	Gaviria, J.	PDF	N/A	Mindfulness training impacts brain network dynamics linked to stress response in young adolescents.
Nlrp3的遗传消除可防止散发性和R345W Efemp1诱导的基底层沉积物形成	Ortega, A. J.	PDF	N/A	Genetic removal of Nlrp3 protects against sporadic and R345W Efemp1-induced basal laminar deposit formation
SARS-CoV-2 XEC变种的病毒学特征	Kaku, Y.	PDF	N/A	Virological characteristics of the SARS-CoV-2 XEC variant
SFSWAP是OGT内含子滞留和全局前体mRNA剪接的负调控因子	Govindan, A.	PDF	N/A	SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing
在大陆尺度的样地网络中，探测生态系统对气候变化和干扰响应的趋势：一项功效分析	Guerin, G. R.	PDF	N/A	Detecting ecosystem trends in response to climate and disturbance across continental plot networks: a power analysis
细菌-噬菌体（共）进化在合成群落中受到多对细菌-噬菌体相互作用的限制	Castledine, M.	PDF	N/A	Bacteria-phage (co)evolution is constrained in a synthetic community across multiple bacteria-phage pairs
用于评估体外细胞表型与整体生物表型相关性的遗传工具变量框架	Howe, L. J.	PDF	N/A	Genetic instrumental variable framework for assessing relevance of in-vitro cellular phenotypes to organism-level phenotypes
对9,482株结核分枝杆菌的拷贝数变异分析揭示了谱系特异性分子决定因素。	Bhalla, N.	PDF	N/A	Copy number variation analysis of 9,482 Mycobacterium tuberculosis isolates identifies lineage-specific molecular determinants.
弯果蓝蓟（Pectocarya recurvata）染色体水平参考基因组，该物种是紫草科中基因组最小的物种之一。	Northing, P. C.	PDF	N/A	Chromosome-scale reference genome of Pectocarya recurvata, a species with one of the smallest genome sizes in Boraginaceae
小分子配体选择性结合RNA单链G凸起的机理研究	Hegde, S.	PDF	N/A	Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges
在人体颈动脉中，如果不进行层分离，无法揭示无应力状态。	Hrubanova, A.	PDF	N/A	Stress-free state in human carotid arteries cannot be revealed without layer separation
使用中位数对单细胞DNA甲基化数据中的缺失值进行插补是一种直接且有效的方法。	Tang, S.	PDF	N/A	Imputing not available values in single-cell DNA methylation data using the median is straightforward and effective
报告H：确定重复序列在基因组间的直系同源位置	Bharadwaj, P. V.	PDF	N/A	REPORTH: Determining orthologous locations of repetitive sequences between genomes
利用药效团建模、QSAR、对接、ADMET、分子动力学和DFT分析发现天然MCL1抑制剂	Das, U.	PDF	N/A	Discovery of Natural MCL1 Inhibitors using Pharmacophore modelling, QSAR, Docking, ADMET, Molecular Dynamics, and DFT Analysis
自动检测和提取生物医学论文表格中的关键资源	Ozyurt, I. B.	PDF	N/A	Automatic Detection and Extraction of Key Resources from Tables in Biomedical Papers
KinPFN：使用先验数据拟合网络的RNA折叠动力学贝叶斯近似	Scheuer, D.	PDF	N/A	KinPFN: Bayesian Approximation of RNA FoldingKinetics using Prior-Data Fitted Networks
一种用于药物反应预测的多模态基因组知识蒸馏框架	Ge, S.	PDF	N/A	A Multi-Modal Genomic Knowledge Distillation Framework for Drug Response Prediction
使用串联质谱库注释全扫描质谱数据	Xing, S.	PDF	N/A	Annotating full-scan MS data using tandem MS libraries
评估AlphaFold2预测的白链结构域构建体的有效性。	Mitic, I.	PDF	N/A	Assessing the Validity of Leucine Zipper Constructs Predicted in AlphaFold2.
利用微流控技术、延时相差显微镜和深度学习快速鉴定七种细菌种类	Hallström, E.	PDF	N/A	Rapid identification of seven bacterial species using microfluidics, time-lapse phase-contrast microscopy, and deep learning
吉波替达辛和左利福达辛如何稳定细菌IIA型拓扑异构酶的DNA切割复合物？2. 单一移动金属机制。	Nicholls, R. A.	PDF	N/A	How do gepotidacin and zolifodacin stabilize DNA-cleavage complexes with bacterial type IIA topoisomerases? 2. A Single Moving Metal Mechanism.
PAR4反应性降低的小鼠表现出静脉血栓形成减少和血小板促凝活性降低	Knauss, E. A.	PDF	N/A	Mice with Reduced PAR4 Reactivity show Decreased Venous Thrombosis and Platelet Procoagulant Activity
苔藓植物小立碗藓中生长素介导的基因激活作用	Bascom, C. S.	PDF	N/A	The role of auxin-mediated gene activation in the bryophyte, Physcomitrium patens
蛋白质解聚酶HSP101对易聚集蛋白质HSA32的稳定作用，在维持拟南芥获得性耐热性中起着关键作用。	Mitra, S.	PDF	N/A	Stabilization of HSA32, an aggregation-prone protein, by the protein disaggregase HSP101 plays a critical role in maintaining acquired thermotolerance in Arabidopsis
APOE基因型和生物学年龄影响与生物能量学相关的多组学关联	Ellis, D. S.	PDF	N/A	APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics
参数依赖性在可识别性中的应用：应用于Tauopathy网络建模参数化的FP-Fisher-KPP反应扩散方程	Rahimabadi, A.	PDF	N/A	Parameter Dependence in Identifiability Applied to FP-Fisher-KPP Reaction-Diffusion Equations Parameterized for Tauopathy Network Modeling
在磁肌电图检测中识别单个运动单位活动	Noury, N.	PDF	N/A	Detecting single motor-unit activity in magnetomyography
揭示星形胶质网络的功能连接性：AstroNet，一种结合图像处理的图重建算法	Zonca, L.	PDF	N/A	Unveiling the Functional Connectivity of Astrocytic Networks with AstroNet, a Graph Reconstruction Algorithm Coupled to Image Processing
皮质微电路在强化学习中的区域特定信用分配	Chevy, Q.	PDF	N/A	A Cortical Microcircuit for Region-Specific Credit Assignment in Reinforcement Learning
户外空气污染与青春期早期杏仁核亚区体积及分布有关	Morrel, J.	PDF	N/A	Outdoor Air Pollution Relates to Amygdala Subregion Volume and Apportionment in Early Adolescents
预测性处理和知觉负荷在选择性视觉注意中的作用：对语义显著和较少显著干扰项的考察	Ozsu, A. B.	PDF	N/A	The Role of Predictive Processing and Perceptual Load in Selective Visual Attention: An Examination with Semantically Salient and Less Salient Distractors
成纤维细胞将上皮营养感应与ILC2-簇细胞回路放大相连接	Liao, C.	PDF	N/A	Telocytes link epithelial nutrient sensing with amplification of the ILC2-tuft cell circuit
了解溃疡性结肠炎患者对JAK抑制剂无反应的机制	Melon-Ardanaz, E.	PDF	N/A	Understanding the mechanisms underlying the lack of response to Janus kinase inhibition in ulcerative colitis
盘尾丝虫空间蛋白质组学与多形性肿瘤显示蛋白质表达的局部和系统性失调	Di Maggio, L. S.	PDF	N/A	Spatial proteomics of Onchocerca volvulus with pleomorphic neoplasms shows local and systemic dysregulation of protein expression
树木在单种和混种邻域中的生物量分配	Perles-Garcia, M. D.	PDF	N/A	Biomass allocation of trees in response to mono- and heterospecific neighbourhoods
用于生长细根的碳的14C年龄反映了树木的碳状态。	Hilman, B.	PDF	N/A	14C-age of carbon used to grow fine roots reflects tree carbon status
缺氧导致珊瑚迅速死亡——对珊瑚礁构成的新兴危险威胁	Dhillon, M. S.	PDF	N/A	Oxygen deprivation implicated in rapid coral mortality -- an emerging perilous threat to coral reefs
利用全球HLA数据提升iPSC配型库中的患者匹配效果	Maiers, M.	PDF	N/A	Harnessing Global HLA Data for Enhanced Patient Matching in iPSC Haplobanks
野生小麦近缘种Aegilops comosa的染色体规模组装与注释	Li, H.	PDF	N/A	Chromosome-scale assembly and annotation of the wildwheat relative Aegilops comosa
通过建模数字PCR的统计特征，改进废水流行病学中的推断	Lison, A.	PDF	N/A	Improving inference in wastewater-based epidemiology by modelling the statistical features of digital PCR
用于罕见疾病药物再利用的知识图谱与可解释人工智能	Perdomo-Quinteiro, P.	PDF	N/A	Knowledge Graphs and Explainable AI for Drug Repurposing on Rare Diseases
在单细胞和空间转录组学中评估替代多聚腺苷酸化检测方法	Li, S.	PDF	N/A	Benchmarking alternative polyadenylation detection in single-cell and spatial transcriptomes
DEMINERS通过提高纳米孔直接RNA测序的通量和准确性，实现了临床宏基因组学和比较转录组学分析。	Song, J.	PDF	N/A	DEMINERS enables clinical metagenomics and comparative transcriptomic analysis by increasing throughput and accuracy of nanopore direct RNA sequencing
在生物语言模型中，跨生物分子模态的知识传递	Prakash, M.	PDF	N/A	Bridging biomolecular modalities for knowledge transfer in bio-language models
吉波替达辛和左利福达辛如何稳定与细菌IIA型拓扑异构酶的DNA切割复合物？1. 金属结合位点的实验定义	Morgan, H.	PDF	N/A	How do gepotidacin and zoliflodacin stabilize DNA-cleavage complexes with bacterial type IIA topoisomerases? 1. Experimental definition of metal binding sites
通过唾液生物标志物评估学术压力：皮质醇、IL-1β、CRP和IgA水平及其性别差异的多变量分析。	Klagges, R. C.	PDF	N/A	Academic stress through salivary biomarkers: A multivariate analysis of cortisol, IL-1β, CRP, and IgA levels and their variations as a function of sex.
利用多环境全基因组关联分析方法研究自然感染条件下石果园中生物胁迫响应的遗传结构	Serrie, M.	PDF	N/A	Investigating the genetic architecture of biotic stress response in stone fruit tree orchards under natural infections with a multi-environment GWAS approach
一项基于模型的元分析支持了新兴的共识观点，即抑制性神经元主导了BOLD-fMRI反应。	Sundqvist, N.	PDF	N/A	A Model-Driven Meta-Analysis Supports the Emerging Consensus View that Inhibitory Neurons Dominate BOLD-fMRI Responses
通过结合新型竞争范式与现有范式揭示的小鼠社会能力与地位的刻板印象	Liu, M.	PDF	N/A	Stereotype of mouse social competency and status revealed by a novel competition paradigm in combination with available paradigms
揭示帕金森病患者运动学习动态	Kim, A.	PDF	N/A	Uncovering locomotor learning dynamics in people with Parkinson's disease
雄性附腺基因的快速启动子进化伴随着在密切相关的果蝇物种中的差异表达	McQuarrie, D. W. J.	PDF	N/A	Rapid promoter evolution of male accessory gland genes is accompanied by divergent expression in closely related Drosophila species
尼日利亚养殖和野生非洲鲶鱼（Clarias gariepinus）的遗传多样性、种群结构和分化	Sanda, M. K.	PDF	N/A	Genetic diversity, population structure and differentiation of farmed and wild African catfish (Clarias gariepinus) in Nigeria
依赖ATP的蛋白酶ClpYQ在枯草芽孢杆菌中降解细胞分裂蛋白DivIVA和Mbl	Lasnosky, T. D.	PDF	N/A	The ATP-dependent protease ClpYQ degrades cell division proteins DivIVA and Mbl in Bacillus subtilis
单羧酸转运蛋白转运甲状腺素的分子机制	Tassinari, M.	PDF	N/A	Molecular mechanism of thyroxine transport by monocarboxylate transporters
利用大型语言模型和基因编辑元数据库探索基因编辑信息的管道	Suzuki, T.	PDF	N/A	Pipeline to explore information on genome editing using large language models and genome editing meta-database
氟NMR研究氨基酸衍生的配体以研究TSPO	Duma, L.	PDF	N/A	Fluor NMR study of amino acid derived ligand to study TSPO
一个共同保守的基因对在螯合应激期间维持柄杆菌的铁稳态中起作用	Ortiz, S. H.	PDF	N/A	A co-conserved gene pair supports Caulobacter iron homeostasis during chelation stress
大肠杆菌在合成废水和实际废水中的抗生素抗性发展特征	Sutradhar, I.	PDF	N/A	Characterization of antibiotic resistance development of E. coli in synthetic and real wastewater
早期抗生素暴露会导致肠道菌群失调，这种失调与神经发育和神经再生有关。	Zhao, Q.	PDF	N/A	Early-life antibiotic exposure leads to gut microbial dysbiosis associated with neurodevelopment and neuroregeneration
Trim7在体内对小鼠诺如病毒感染的限制中没有作用。	Annaswamy Srinivas, M.	PDF	N/A	Trim7 does not have a role in the restriction of murine norovirus infection in vivo
利用番茄废弃物提取物增强着色菌（Exiguobacterium aurantiacum）的色素生产：一种统计学方法	Zeleke, B.	PDF	N/A	Enhancing pigment production by a chromogenic bacterium (Exiguobacterium aurantiacum) using tomato waste extract: A Statistical approach
SMC 调节链霉菌中分离复合体中 ParB 的参与	Pawlikiewicz, K.	PDF	N/A	SMC modulates ParB engagement in segregation complexes in Streptomyces
鉴定SLC35A1为多血清型重组腺相关病毒（AAV）载体转导的关键宿主因子	Zhang, X.	PDF	N/A	Identification of SLC35A1 as an essential host factor for the transduction of multi-serotype recombinant adeno-associated virus (AAV) vectors
自发T2DM猕猴的多组学研究揭示肠道微生物通过上调过量棕榈酸的吸收促进T2DM	Liu, X.	PDF	N/A	Multi-omics investigation of spontaneous T2DM macaque reveals gut microbiota promote T2DM by up-regulating the absorption of excess palmitic acid
在持续念珠菌血症期间和基线时的血液培养物中，含有遗传多样性不同的白色念珠菌菌株，这些菌株在棘白菌素耐药性和毒力方面可能存在差异。	Fleres, G.	PDF	N/A	Blood cultures at baseline and during persistent candidemia contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and virulence
指导多物种有益生物膜的组装，以针对不良细菌	Gueneau, V.	PDF	N/A	Guided assembly of multispecies positive biofilms targeting undesirable bacteria
肌球蛋白轻链3通过巨胞饮途径作为神经坏死病毒进入宿主细胞的受体	Yao, L.	PDF	N/A	Myosin light chain 3 serves as a receptor for nervous necrosis virus entry into host cells via the macropinocytosis pathway
通过同时进行转录起始位点定位和甲基化定量来解析m6Am	Liu, J. F.	PDF	N/A	Decoding m6Am by simultaneous transcription-start mapping and methylation quantification
靶向降解HPV癌蛋白E6可减轻宫颈癌的肿瘤负担	Smalley, T. B.	PDF	N/A	Targeted degradation of the HPV oncoprotein E6 reduces tumor burden in cervical cancer
一种用于多环四胺大环内酰胺表达和功能化的即插即用系统	Gloeckle, A.	PDF	N/A	A Plug-and-Play System for Polycyclic Tetramate Macrolactam Expression and Functionalization
胚胎细胞起源及缺氧介导机制在PIK3CA驱动难治性血管畸形中的作用	Torii, S.	PDF	N/A	Embryological cellular origins and hypoxia-mediated mechanisms in PIK3CA-Driven refractory vascular malformations
一种首创的双降解剂，针对Bcl-2/Bcl-xL，能够逆转HIV潜伏状态并消除体外储藏库	Chang, L.-C.	PDF	N/A	A First-in-Class Dual Degrader of Bcl-2/Bcl-xL Reverses HIV Latency and Eliminates Ex Vivo Reservoirs
rRNA特异性反义DNA和双链DNA触发rRNA生物合成，并对柑橘害虫Coccus hesperidum L.产生强大的杀虫效果。	Oberemok, V. V.	PDF	N/A	rRNA-specific antisense DNA and dsDNA trigger rRNA biogenesis and cause potent insecticidal effect on insect pest Coccus hesperidum L.
鉴定眼病病原体棘阿米巴的包囊（四种）和滋养体（一种）的新诊断靶标	Sundararaj, B. K.	PDF	N/A	Identification of new targets for the diagnosis of cysts (four) and trophozoites (one) of the eye pathogen Acanthamoeba
通过在人类线粒体中重构末端连接来生成线粒体DNA缺失	sfeir, a.	PDF	N/A	Engineering mtDNA Deletions by Reconstituting End-Joining in Human Mitochondria
利用双特异性抗体实现mRNA靶向递送，将脂质纳米颗粒（LNPs）锚定于细胞表面标志物	Dietmair, B.	PDF	N/A	Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers
用于活细胞和体内成像的荧光阴离子菁染料质膜探针	Danylchuk, D. I.	PDF	N/A	Fluorescent anionic cyanine plasma membrane probes for live cell and in vivo imaging
酮体生成通过脂肪氧化非依赖性机制保护免受MASLD-MASH进展的影响	Queathem, E. D.	PDF	N/A	Ketogenesis protects against MASLD-MASH progression through fat oxidation-independent mechanisms
METTL3-METTL14对Drosha-DGCR8介导的初级microRNA加工的影响	Khadgi, B. B.	PDF	N/A	Effects of METTL3-METTL14 on primary microRNA processing by Drosha-DGCR8
媒体品牌对头孢地尔盘扩散结果的影响	DeMarco, M. G.	PDF	N/A	Impact of media brand on cefiderocol disk diffusion results
TamL是拟杆菌门中维持外膜稳态的关键因子。	Giovannercole, F.	PDF	N/A	TamL is a key player of the outer membrane homeostasis in Bacteroidetes.
实验室的可持续性：评估微孔板在PCR和片段检测中的重复使用性	Berthelsen, A. L.	PDF	N/A	Sustainability in the laboratory: evaluating the reuseability of microtiter plates for PCR and fragment detection
从淡水斑马贻贝（Dreissena bugensis）中提取的湿粘附蛋白的鉴定与表征	Obille, A. R.	PDF	N/A	Identification and characterization of a wet adhesive protein extracted from Dreissena bugensis, the freshwater quagga mussel
两个保守的精氨酸残基促进Suf家族半胱氨酸脱硫酶中的C-S键断裂和硫化物转移。	Gogar, R. K.	PDF	N/A	Two conserved arginine residues facilitate C-S bond cleavage and persulfide transfer in Suf family cysteine desulfurases.
克拉伯病GALC错义变异的表达研究——基于残留酶活性、分泌量及神经鞘氨醇半乳糖苷水平的定量分析所获得的洞见	Peng, H.	PDF	N/A	Expression study of Krabbe Disease GALC missense variants -- Insights from quantification profiles of residual enzyme activity, secretion and psychosine levels
MLL/WDR5复合体招募KIF2C至中间体，以确保在有丝分裂期间微管解聚和收缩环压缩。	Kataria, A.	PDF	N/A	MLL/WDR5 complex recruits KIF2C to midbody to ensure MT depolymerization and furrow compaction during cytokinesis
由Mnl1甘露糖苷酶和蛋白质二硫键异构酶双功能复合物启动的内质网相关降解（ERAD）过程	Zhao, D.	PDF	N/A	Initiation of ERAD by the bifunctional complex of Mnl1 mannosidase and protein disulfide isomerase
ZO-2支架机制调控Hippo信号通路。	Liu, O.	PDF	N/A	A ZO-2 scaffolding mechanism regulates the Hippo signalling pathway.
细胞周期蛋白A和细胞周期蛋白B的mRNA转录后调控由Bruno 1和Cup介导，并在P-bodies内进一步微调。	Bayer, L. V.	PDF	N/A	Post-transcriptional regulation of cyclin A and cyclin B mRNAs is mediated by Bruno 1 and Cup, and further fine-tuned within P-bodies
一种残留角膜缘干细胞的角膜缘干细胞缺乏小鼠模型	Someya, H.	PDF	N/A	A limbal stem cell deficiency murine model with residual limbal stem cells
乳腺上皮细胞迁移与上皮-间质转化无关	Chen, J.	PDF	N/A	Mammary Epithelial Migration is EMT-Independent
中性粒细胞表现出不同的迁移表型，这些表型受跨内皮迁移的调节。	Schwartz, A. B.	PDF	N/A	Neutrophils exhibit distinct migration phenotypes that are modulated by transendothelial migration
柠檬酸合酶通过重构巨噬细胞的线粒体三羧酸循环，改善了脓毒症诱导的肺损伤。	Sun, J.	PDF	N/A	Citrate synthase improves sepsis-induced lung injury by reconstructing the mitochondrial tricarboxylic acid cycle of macrophages
选择性静止期酵母细胞的协调分工扩大了休眠期种群的存活率	Hsiao, K.-C.	PDF	N/A	Coordinated Division of Selective Stationary-Phase Yeast Cells Expands the Population Survivorship in Quiescence
可视化果蝇核形态和运输机制的发育动力学	Shindo, Y.	PDF	N/A	Visualizing developmental dynamics of nuclear morphology and transport machinery in Drosophila
在诱导关节炎症后，肠道炎症和免疫转录物被沉默的证据	Moran, M. M.	PDF	N/A	Evidence of Silencing of Intestinal Inflammatory and Immune Transcripts Following Induction of Joint Inflammation
小分子定向分化浸没培养的人鼻气道上皮用于呼吸疾病建模	Dreyer, H. H. M.	PDF	N/A	Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling
物理信息椭球坐标编码隐式神经表示用于高分辨率体积宽视野显微镜	Zhou, Y.	PDF	N/A	Physics-Informed Ellipsoidal Coordinate Encoding Implicit Neural Representation for high-resolution volumetric wide-field microscopy
羟基脲诱导内质网应激和细胞质蛋白聚集	Sanchez-Molina, A.	PDF	N/A	Hydroxyurea induces ER stress and cytoplasmic protein aggregation
初级纤毛通过音猬信号通路塑造出生后星形胶质细胞的发育	Bear, R.	PDF	N/A	Primary cilia shape postnatal astrocyte development through Sonic Hedgehog signaling
儿童在标准与奖励性Go/No-Go任务需求下大脑网络的差异重构	Mitchell, M. E.	PDF	N/A	Differential reconfiguration of brain networks in children in response to standard versus rewarded go/no-go task demands
冬眠哺乳动物适应性生理转变背后的基因	Drabeck, D. H.	PDF	N/A	Genes Underlying Adaptive Physiological Shifts Among Hibernating Mammals
# BioRxiv 2024-10-16 Papers

标题	作者	PDF链接	代码仓库	Title
长期胞外记录中神经活动追踪的通用框架	Chaure, F. J.	PDF	N/A	General Framework for Tracking Neural Activity Over Long-Term Extracellular Recordings
池塘蜻蜓生态位的持久性，奠定了尽管选择变异，适应区依然稳定的基础。	Gupta, A.	PDF	N/A	Persistence of the ecological niche in pond damselflies underlies a stable adaptive zone despite varying selection
鼻内自我扩增RNA SARS-CoV-2疫苗产生保护性呼吸和系统性免疫，并防止病毒传播。	Jennewein, M. F.	PDF	N/A	Intranasal self-amplifying RNA SARS-CoV-2 vaccine produces protective respiratory and systemic immunity and prevents viral transmission
利用PlatinumCRISPr进行结构优化的sgRNA选择，以高效生成Cas9敲除	Haussmann, I. U.	PDF	N/A	Structure-optimized sgRNA selection with PlatinumCRISPr for efficient Cas9 generation of knock-outs
全基因组测序数据中剪接改变变异的函数聚类揭示了罕见变异疾病的隐藏遗传性	Wang, Y.	PDF	N/A	Functional clustering of splice-altering variants in whole genome sequencing data reveals hidden heritability in rare variant disorder
视觉空间动力学驱动沉浸式环境中的适应性社会学习	Wu, C. M.	PDF	N/A	Visual-spatial dynamics drive adaptive social learning in immersive environments
saseR：平衡偏移量解锁了RNA测序工具，实现快速、可扩展的差异使用、异常剪接和表达检索。	Segers, A.	PDF	N/A	saseR: Juggling offsets unlocks RNA-seq tools for fast and Scalable differential usage, Aberrant Splicing and Expression Retrieval.
鉴定允许鲍氏不动杆菌维持高水平氟喹诺酮类耐药性的决定因素	Hamami, E.	PDF	N/A	Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii
预测基于CRISPR-Cas9的表观基因组编辑效果	Batra, S. S.	PDF	N/A	Predicting the effect of CRISPR-Cas9-based epigenome editing
通过免疫球蛋白A抑制上皮细胞增殖和肿瘤发生	Donaldson, G. P.	PDF	N/A	Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A
小鼠眶额皮层中信息内在价值的表征	Bussell, J. J.	PDF	N/A	Representations of the intrinsic value of information in mouse orbitofrontal cortex
高效编码解释了神经响应稳态和刺激特异性适应	Young, E. J.	PDF	N/A	Efficient coding explains neural response homeostasis and stimulus-specific adaptation
食物竞争影响繁殖干扰的强度及其对物种共存的后果。	Cruz, M. A.	PDF	N/A	Competition for food affects the strength of reproductive interference and its consequences for species coexistence.
热带马利筋（Asclepias curassavica）的基因组和组织特异性转录组	Feng, H.	PDF	N/A	Genome and tissue-specific transcriptome of the tropical milkweed (Asclepias curassavica)
靶向星形胶质细胞可减轻脊髓损伤后的神经病理性疼痛	Zhao, Q.	PDF	N/A	Targeting resident astrocytes attenuates neuropathic pain after spinal cord injury
在酵母极性网络的补偿性进化过程中，全球基因重塑	Kingma, E.	PDF	N/A	Global genetic rewiring during compensatory evolution in the yeast polarity network
tRNA低修饰通过激活交叉途径控制系统促进烟曲霉对5-氟胞嘧啶的抗性。	Bruch, A.	PDF	N/A	tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.
在变量选择前的排列分析大大增强了OPLS分析在小样本群体中的鲁棒性。	Ström, M.	PDF	N/A	The permutation analysis prior to variable selection greatly enhances robustness of OPLS analysis in small cohorts
PRC2.1亚复合物通过调节CCND1和CCND2来抑制G1期进展	Longhurst, A. D.	PDF	N/A	The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2
遗传多样性对跨越营养级的生态系统功能的影响与物种多样性一样大，但方向相反。	Fargeot, L.	PDF	N/A	Genetic diversity affects ecosystem functions across trophic levels as much as species diversity, but in an opposite direction
自上而下起源的捕食者-猎物幂律的一般机制	Mazzarisi, O.	PDF	N/A	General mechanisms for a top-down origin of the predator-prey power law
AgeML：利用机器学习进行年龄建模	Garcia Condado, J.	PDF	N/A	AgeML: Age modelling with Machine Learning
沃尔巴克氏菌增强了交配前和交配后早期隔离在螨虫中的匹配度	Cruz, M. A.	PDF	N/A	Wolbachia strengthens the match between pre-mating and early post-mating isolation in spider mites
BIMSA：利用内存处理加速长序列比对	Alonso-Marin, A.	PDF	N/A	BIMSA: Accelerating Long Sequence Alignment Using Processing-In-Memory
大规模基因组重排的爆发式发生与非海洋环节动物的起源	Vargas-Chavez, C.	PDF	N/A	A punctuated burst of massive genomic rearrangements and the origin of non-marine annelids
谷氨酸/GABA共传递的独特释放特性起到了对上丘脑输入的频率依赖性过滤作用。	Hirai, H.	PDF	N/A	Distinct release properties of glutamate/GABA co-transmission serve as a frequency-dependent filtering of supramammillary inputs
diaTracer能够对基于diaPASEF的蛋白质组学数据进行以光谱为中心的分析。	Li, K.	PDF	N/A	diaTracer enables spectrum-centric analysis of diaPASEF proteomics data
规模至关重要：拥有数十亿（而非数百万）参数的大型语言模型更能与自然语言的神经表征相匹配。	Hong, Z.	PDF	N/A	Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language
提取后去甲肾上腺素激活会损害后续记忆，这取决于皮层-海马再激活的作用。	Heinbockel, H.	PDF	N/A	Post-retrieval noradrenergic activation impairs subsequent memory depending on cortico-hippocampal reactivation
第三种情景记忆：情景熟悉度与项目熟悉度和回忆是不同的	Addante, R. J.	PDF	N/A	A third kind of episodic memory: Context familiarity is distinct from item familiarity and recollection
北亚得里亚海（地中海）中入侵物种波氏多毛虫（多毛纲：缨鳃虫科）的大量存在	Lezzi, M.	PDF	N/A	Massive presence of the invasive Polydora websteri (Polychaeta: Spionidae) in the North Adriatic Sea (Mediterranean Sea)
在正常听力中年成人中，增加的听力努力和耳蜗神经退化是导致噪音环境下言语感知行为缺陷的基础。	Zink, M. E.	PDF	N/A	Increased listening effort and cochlear neural degeneration underlie behavioral deficits in speech perception in noise in normal hearing middle-aged adults.
大型蛋白质数据库揭示了结构互补性和功能局部性	Szczerbiak, P.	PDF	N/A	Large protein databases reveal structural complementarity and functional locality
用于可视化多胺水平、摄取和分布的基因编码荧光传感器	Tamura, R.	PDF	N/A	Genetically encoded fluorescent sensors for visualizing polyamine levels, uptake, and distribution
使用Glittr.org查找、比较并重复利用在线培训和教育材料	van Geest, G.	PDF	N/A	Using Glittr.org to find, compare and re-use online materials for training and education
旁分泌拯救MYR1缺陷型刚地弓形虫突变体揭示了体内CRISPR筛选的局限性	Torelli, F.	PDF	N/A	Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens
ERGtools2 包：用于处理和分析视觉电生理数据的工具集	Lindner, M.	PDF	N/A	The ERGtools2 package: A Toolset for Processing and Analysing Visual Electrophysiology Data
物体非刚性各向异性：皮层各向异性的高级知觉后果	Maruya, A.	PDF	N/A	Anisotropy of object nonrigidity: High-level perceptual consequences of cortical anisotropy
果蝇piRNA通路中蛋白质相互作用的反复创新	Riedelbauch, S.	PDF	N/A	Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway
数据驱动的改进抗体选择适宜免疫原评估	Waury, K.	PDF	N/A	Data-driven evaluation of suitable immunogens for improved antibody selection
区域特异性扩散去极化驱动异常的癫痫后行为	Mitlasoczki, B.	PDF	N/A	Region-specific spreading depolarization drives aberrant post-ictal behavior
生物学中的弱磁场效应是可以测量的——在不存在地磁场的情况下，非洲爪蟾胚胎发育加速。	Lodesani, A.	PDF	N/A	Weak magnetic field effects in biology are measurable--accelerated Xenopus embryogenesis in the absence of the geomagnetic field
利用新型基因组资源和统计方法结合个体和群体测序数据，深入探讨过去和未来斑翅果蝇（Drosophila suzukii）的入侵情况	Camus, L.	PDF	N/A	New insights into past and future invasion of Drosophila suzukii using novel genomic resources and statistical methods to combine individual and pool sequencing data
自催化循环的热力学一致性	Kosc, T.	PDF	N/A	Thermodynamic consistency of autocatalytic cycles
印度荠菜（Rorippa indica）的种内基因组大小变异揭示了通过基因组扩增实现的热带适应性	Han, T.-S.	PDF	N/A	Intraspecific genome size variation in Rorippa indica reveals a tropical adaptation by genomic enlargement
大鼠从空间距离到社交距离的信息传递：对后顶叶皮层在空间-社交整合中作用的影响	Wise, T. B.	PDF	N/A	Information transfer from spatial to social distance in rats: implications for the role of the posterior parietal cortex in spatial-social integration
隔离节拍显著性对节奏听觉刺激效果的影响	Von Handorf, K. M.	PDF	N/A	Isolating the effect of beat salience on rhythmic auditory stimulation outcomes
人类腹侧颞叶皮层功能侧化的个体差异：局部竞争与长程耦合	Blauch, N. M.	PDF	N/A	Individual variation in the functional lateralization of human ventral temporal cortex: Local competition and long-range coupling
从动作到言语：内侧额叶皮层沿着尾侧到吻侧的预测误差梯度进行动作监控	Dorokhova, L.	PDF	N/A	From movements to words: action monitoring in the medial frontal cortex along a caudal to rostral prediction error gradient
注意力网络在不确定情况下与策略精确性相关的默认模式网络中发挥作用。	Yoon, D.	PDF	N/A	Attention networks engage the default mode network related to policy precision under uncertainty
ZMYND11 在双模态调控潜伏基因和类脑剪接中发挥作用，以保障皮层发生	Chang, X.	PDF	N/A	ZMYND11 Functions in Bimodal Regulation of Latent Genes and Brain-like Splicing to Safeguard Corticogenesis
脆性X综合征大鼠模型中受损的海马-前额叶网络：一项将神经动力学与自闭症样行为障碍联系起来的研究	Ouardouz, M.	PDF	N/A	Disrupted Hippocampal-Prefrontal Networks In A Rat Model Of Fragile X Syndrome: A Study Linking Neural Dynamics To Autism-Like Behavioral Impairments
细胞外控制对新皮质神经元命运和多样性的影响	Baumann, N.	PDF	N/A	Cell-extrinsic controls over neocortical neuron fate and diversity
快速且稳健的幼儿视觉物体识别	Ayzenberg, V.	PDF	N/A	Fast and robust visual object recognition in young children
海马齿状回颗粒细胞亚型的多样化受Neuregulin1核反馈信号的调控。	Rajebhosale, P.	PDF	N/A	Diversification of Dentate Gyrus Granule Cell Subtypes is Regulated by Neuregulin1 Nuclear Back Signaling.
增强小鼠发声的皮层-运动神经元投射	Boyd, J. L.	PDF	N/A	Enhancing cortico-motoneuronal projections for vocalization in mice
光学分析突触和突触外位点的NMDA受体分子多样性	Sicard, A.	PDF	N/A	Optical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites
一个自上而下的岛叶皮层回路，对非伤害性恐惧学习至关重要	Han, J.	PDF	N/A	A top-down insular cortex circuit crucial for non-nociceptive fear learning
CB1大麻素受体和囊泡谷氨酸转运体-3表达神经末梢在大脑皮层中与GABA能神经元相关的突触靶点和细胞来源	Somogyi, P.	PDF	N/A	Synaptic targets and cellular sources of CB1 cannabinoid receptor and vesicular glutamate transporter-3 expressing nerve terminals in relation to GABAergic neurons in the human cerebral cortex
不同物种和多种生物因素下祖先脑干去甲肾上腺素能神经元的多样性	Kelberman, M. A.	PDF	N/A	Diversity of ancestral brainstem noradrenergic neurons across species and multiple biological factors
欧亚松鸦（Garrulus glandarius）在食物储藏中的排除推理	Hawkins, I.	PDF	N/A	Reasoning by exclusion in food-caching Eurasian jays (Garrulus glandarius)
老鼠在意什么？内外环境对雄性对雌性尖叫声的反应的影响	Brunner, L. R.	PDF	N/A	What matters to a mouse? Effects of internal and external context on male vocal response to female squeaks
宽吻海豚的哨声变异及其社会声学互动	Mustun, F.	PDF	N/A	Whistle variability and social acoustic interactions in bottlenose dolphins
规范性脑形态计量学模型在不同种族群体中的普适性	Ge, R.	PDF	N/A	Generalizability of Normative Models of Brain Morphometry Across Distinct Ethnoracial Groups
奖励驱动的运动适应需要强大的基底神经节-皮质回路	Leblois, A.	PDF	N/A	Reward-driven adaptation of movements requires strong recurrent basal ganglia-cortical loops
同步动力学是导致不规则新皮层放电的潜在机制。	Pattadkal, J. J.	PDF	N/A	Synchrony dynamics underlie irregular neocortical spiking
P73+ Cajal-Retzius细胞和Reelin在皮质形态发生中的不同贡献	Elorriaga, V.	PDF	N/A	Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical morphogenesis
阿尔茨海默病早期糖萼系统健康及其与睡眠、认知和脑脊液生物标志物的关系。	Ray, N. J.	PDF	N/A	Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers.
早期阿尔茨海默病中的淋巴系统健康及其与睡眠、认知和脑脊液生物标志物的关系。	Ray, N. J.	PDF	N/A	Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers.
一个编码发声表达和接收的皮层位点	Pomberger, T.	PDF	N/A	A Cortical Site that Encodes Vocal Expression and Reception
克里斯托弗·哥伦布家族成员的首个全面法医遗传学研究：他的曾曾孙	Navarro Vera, I.	PDF	N/A	THE FIRST COMPREHENSIVE FORENSIC GENETIC STUDY OF A MEMBER OF CHRISTOPHER COLUMBUS' FAMILY: HIS GREAT-GREAT-GRANDSON
填补免疫治疗预测的空白：AGAE评分作为免疫检查点抑制剂反应的泛癌生物标志物	Ye, B.	PDF	N/A	Bridging the Gap in Immunotherapy Prediction: The AGAE Score as a Pan Cancer Biomarker for Immune Checkpoint Inhibitor Response
Galectin-4-KO小鼠中记忆缺陷、长期增强作用及海马突触可塑性	Brocca, M. E.	PDF	N/A	Deficient Memory, Long-Term Potentiation and Hippocampal Synaptic Plasticity in Galectin-4-KO Mice.
阵发性慢波事件作为创伤后癫痫的诊断和预测生物标志物	Van Hameren, G.	PDF	N/A	Paroxysmal Slow Wave Events as a diagnostic and predictive biomarker for post-traumatic epilepsy
快速发作性肌张力障碍-帕金森病中的网络机制	Moeller, M.	PDF	N/A	Network mechanisms in rapid-onset dystonia-parkinsonism
跑步机步态训练促进不完全脊髓损伤后的皮质脊髓束可塑性	Eisdorfer, J. T.	PDF	N/A	Treadmill step training promotes corticospinal tract plasticity after incomplete spinal cord injury
端粒长度与中老年参与者认知功能的关系：来自老龄研究中代表性不足社区的初步研究	McLester-Davis, L. W. Y.	PDF	N/A	Telomere length and cognitive function among middle-aged and older participants from communities underrepresented in aging research: A preliminary study
在破伤风毒素诱发的癫痫大鼠模型中动态多日癫痫发作周期：节奏演变及其对预测的启示	Zarei Eskikand, P.	PDF	N/A	Dynamic Multiday Seizure Cycles in a Tetanus Toxin Rat Model of Epilepsy: Evolving Rhythms and Implications for Prediction
隐含的运动既不引导目光跟随，也不引导意图归属。	Görner, M.	PDF	N/A	Implied motion guides neither gaze following nor intention attribution
心磷脂通过阻止LPS与Caspase 4/11结合，抑制非经典炎症小体，从而减轻体内的内毒素血症	Pizzuto, M.	PDF	N/A	Cardiolipin Inhibits the Noncanonical Inflammasome by Preventing LPS Binding to Caspase 4/11 to Mitigate Endotoxemia in Vivo
对埃塞俄比亚索马里地区新出现的皮肤利什曼病疫源地中一种独特的利什曼原虫热带种群体进行基因组特征分析	Abera, A.	PDF	N/A	Genomic characterization of a unique population of Leishmania tropica in a new emerging focus of cutaneous leishmaniasis in Somali region of Ethiopia
PAF1C在RNAPII转录延伸过程中，别构激活CDK12/13激酶。	Lopez Martinez, D.	PDF	N/A	PAF1C allosterically activates CDK12/13 kinase during RNAPII transcript elongation
太阳辐射的漫射比和光谱特性的年变化：温带季风区域的云层效应	Siriwardana, A. N.	PDF	N/A	Annual Variability in Diffuse Ratio and Spectral Characteristics of Solar Radiation: Cloud Effects in a Temperate Monsoon Region
植物性状数据来源的重要性：西北欧和潘诺尼亚生态区的共有物种在两个地区的性状值不同	Sonkoly, J.	PDF	N/A	Origin of plant trait data matters: Shared species of Northwestern Europe and the Pannonian Ecoregion have different trait values in the two regions
一种可传播癌症对袋獾生命史特征的影响	Strickland, K.	PDF	N/A	Effects of a transmissible cancer on life-history traits in Tasmanian devils
多样化的祖先揭示了真核生物起源时期复杂的共生相互作用	Bernabeu, M.	PDF	N/A	Diverse ancestries reveal complex symbiotic interactions during eukaryogenesis
在密集环境中，大黄蜂会提高其学习飞行的海拔。	Sonntag, A.	PDF	N/A	Bumblebees increase their learning flight altitude in dense environments
小鼠中的精细社会歧视：对阿尔茨海默病早期检测的启示	Faure, L. M.	PDF	N/A	Fine Social Discrimination of Siblings in Mice: Implications for Early Detection of Alzheimer's Disease
野生环境中，更大的鱼群能做出更好、更快的集体决策	Pacher, K.	PDF	N/A	Better and faster collective decisions by larger fish shoals in the wild
酒精诱导的DNA交联修复的机制性见解：范可尼贫血核酸酶Slx4-Xpf-Ercc1的作用	Havlikova, J.	PDF	N/A	Mechanistic Insights into Alcohol-Induced DNA Crosslink Repair by the Fanconi Anemia Nuclease Slx4-Xpf-Ercc1
利用冷冻电子断层扫描技术绘制海马体内神经元组织结构的分子图谱	Glynn, C.	PDF	N/A	Charting the molecular landscape of neuronal organisation within the hippocampus using cryo electron tomography
无压力生物打印保留功能的人类原代和iPSC衍生的胰岛	Poklar, M.	PDF	N/A	Stress-free Bioprinting of Human Primary and iPSC-derived Islets with Retained Functionality
全面肿瘤治疗场系统用于胶质母细胞瘤治疗的开发与验证：从原型设计到临床前评估	Wang, X.	PDF	N/A	Development and Validation of a Comprehensive Tumor Treating Fields System for Glioblastoma Therapy: From Prototype Design to Preclinical Evaluation
在HA(pY)STACK中搜索磺酸酪氨酸（sY）	Tzvetkov, J.	PDF	N/A	Searching for Sulfotyrosines (sY) in a HA(pY)STACK
一种基于语义引导元路径方法的药物-靶标相互作用预测统一框架	Li, H.	PDF	N/A	A unified framework for drug-target interaction prediction by semantic-guided meta-path method
非线性奇异值分解波束形成用于气泡超声成像	Zhang, G.	PDF	N/A	Nonlinear Singular Value Decomposition Beamforming for Ultrasound Imaging of Gas Vesicles
慢性肥胖并不改变Tp53R270H/+小鼠的癌症生存率。	Panzeri, I.	PDF	N/A	Chronic obesity does not alter cancer survival in Tp53R270H/+ mice
PPARα-ERRα交叉对话缓解了与代谢功能障碍相关的脂肪肝疾病进展	Antwi, M. B.	PDF	N/A	PPARalpha-ERRalpha crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression
预测无脊椎动物对化学物质的吸收和消除动力学：关于残差方差建模的技术说明	van Lingen, H. J.	PDF	N/A	Predicting uptake and elimination kinetics of chemicals in invertebrates: a technicalnote on residual variance modeling
GCS-H2对于生长至关重要，因为它在拟南芥异养组织中作为线粒体脂酰化的主要中继器发挥作用。	Przybyla-Toscano, j.	PDF	N/A	GCS-H2 is essential for growth as it acts as the main relay for mitochondrial lipoylation in heterotrophic tissues of Arabidopsis thaliana
基于数据和知识的溶质载体功能景观	Goldmann, U.	PDF	N/A	Data- and knowledge-derived functional landscape of human solute carriers
降低与激活负担基因电路相关的切换成本，有助于提高细胞群体的均一性和生产力。	Henrion, L.	PDF	N/A	Lowering the switching cost related to the activation of burdensome gene circuits promotes cell population homogeneity and productivity
系统级分析揭示了由甲基营养菌（Bacillus methanolicus）以甲醇为原料生产L-谷氨酸及其脱羧产物γ-氨基丁酸的机制。	Irla, M.	PDF	N/A	Systems-level analysis provides insights on methanol-based production of L-glutamate and its decarboxylation product γ-aminobutyric acid by Bacillus methanolicus
生物抗性可预测地改变微生物入侵模式	Ye, X.	PDF	N/A	Biotic resistance predictably shifts microbial invasion regimes
人类大脑广泛激活的睡眠节律	Wang, H.	PDF	N/A	Human Brain-Wide Activation of Sleep Rhythms
Prefoldin 5 是一种微管相关蛋白，能够抑制Tau蛋白的聚集和神经毒性。	Bisht, A.	PDF	N/A	Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity
大鼠暴露于自助餐厅饮食后腹侧被盖区的行为和神经改变	Lalanza, J. F.	PDF	N/A	Behavioral and neural alterations of the ventral tegmental area by Cafeteria diet exposure in rats
眼动搜索任务与手动搜索任务中搜索成本与准确性之间的权衡	Wagner, I.	PDF	N/A	Trade-off between search costs and accuracy in oculomotor and manual search tasks
GLE1功能障碍会破坏细胞内稳态、空间组织以及周围轴突的分支。	Zarybnicky, T.	PDF	N/A	GLE1 dysfunction compromises cellular homeostasis, spatial organization, and peripheral axon branching
荷兰未来关键鸟类物种的病原体传播丰富度	Dellar, M.	PDF	N/A	The future abundance of key bird species for pathogen transmission in the Netherlands
使用GEV分布纳入气候极端情况可以提高物种分布模型（SDM）在范围边缘的表现。	Fonteyn, W.	PDF	N/A	Incorporating climatic extremes using the GEV distribution improves SDM range edge performance
柳树中的一种新型下游因子取代了祖先的性别决定基因	Wang, Y.	PDF	N/A	A novel downstream factor in willows replaces the ancestral sex determining gene
TRENDY：基于Transformer的基因调控网络推断增强技术	Tian, X.	PDF	N/A	TRENDY: Gene Regulatory Network Inference Enhanced by Transformer
214份玉米自交系叶片可及染色质区域的泛顺反子分析	Zhu, Y.	PDF	N/A	Pan-cistrome analysis of the leaf accessible chromatin regions of 214 maize inbred lines
与UmV-KP4和UmV-KP6结构相关的小麦白粉菌蛋白对真菌具有毒性，并定义了真菌效应因子的新型结构家族。	de Guillen, K.	PDF	N/A	Zymoseptoria tritici proteins structurally related to UmV-KP4 and UmV-KP6 are toxic to fungi, and define novel structural families of fungal effectors
钙调素调控的顺式和反式E-钙粘蛋白EC1-2相互作用在钙粘蛋白连接的形成、动态变化和可塑性中起着关键作用。	Bron, P.	PDF	N/A	Calcium-modulated cis and trans E-cadherin EC1-2 interactions play a key role in formation, dynamics and plasticity of cadherin junctions
ATP门控的P2x7受体是II型听觉神经的主要通道类型，对于听觉敏感性的传出控制和噪音保护是必需的。	Liang, C.	PDF	N/A	ATP-gated P2x7 receptor is a major channel type at type II auditory nerves and required for hearing sensitivity efferent controlling and noise protection
在自我认知的元认知中，运动与结果表征的分离	Charalampaki, A.	PDF	N/A	Dissociation of movement and outcome representations in metacognition of agency
PEPITEM 三肽和拟肽：免疫介导条件下炎症的下一代调节剂	Saviano, A.	PDF	N/A	PEPITEM Tripeptides and Peptidomimetics: Next-Generation Modulators of Inflammation in Immune-Mediated Conditions
真核生物中基于DAG的Dip2介导的特异性PKC信号轴的形成	Shambhavi, S.	PDF	N/A	Emergence of Dip2-mediated Specific DAG-based PKC Signalling Axis in Eukaryotes
Asgard古菌对真核生物起源的显著贡献	Tobiasson, V.	PDF	N/A	Dominant contribution of Asgard archaea to eukaryogenesis
EF-24的基因组发现揭示了白血病细胞中的抗肿瘤机制	Singh, A. P.	PDF	N/A	Genomic Discovery of EF-24 Targets Unveils Antitumorigenic Mechanisms in Leukemia Cells
在膝关节屈曲和髋关节伸展任务中，股二头肌长头的远端激活程度更高，这反映了外周而非中枢运动单位特性的差异。	Albarello, J. C. d. S.	PDF	N/A	Greater distal activation of the biceps femoris long head during knee flexion and hip extension tasks reflects differences in peripheral, not central, motor unit properties.
尽管mHTT聚集增加，Q175DN小鼠的海马备用容量增强	Solem, M. A.	PDF	N/A	Enhanced Hippocampal Spare Capacity in Q175DN Mice Despite Elevated mHTT Aggregation
高阶转录组组织与RNA凝聚原理的综合分析	Klobucar, T.	PDF	N/A	Integrative analysis of higher-order transcriptome organisation and RNA condensation principles
感知专长与注意力：基于深度神经网络的探索	Das, S.	PDF	N/A	Perceptual Expertise and Attention: An Exploration using Deep Neural Networks
亚马逊生物文化遗产在气候变化下的状况	Camara-Leret, R.	PDF	N/A	Amazonian biocultural heritage under climate change
孟加拉国代谢综合征患者血浆脂联素水平研究及治疗指征	Parul, S. S.	PDF	N/A	Study of Plasma Adiponectin Levels in Patients with Metabolic Syndrome and Therapeutic Indication in Bangladesh
孕期压力、线粒体健康与妊娠周数之间的关系：来自美国和土耳其两项妊娠研究的发现	Huang, Q.	PDF	N/A	Associations between prenatal distress, mitochondrial health, and gestational age: findings from two pregnancy studies in the USA and Turkey
元分析：使用磁性纳米颗粒提取的人血DNA、大肠杆菌gDNA和质粒的纯度	Tjoa, S. E. E.	PDF	N/A	Meta-analysis: Purity of extracted human blood DNA, E. coli gDNA, and plasmid using magnetic nanoparticle
利用自体血液构建神经血管组织以模拟脑活动	Arora, R.	PDF	N/A	Building neurovascular tissue from autologous blood for modeling brain-activity
表观遗传轨迹预测ACPA阳性个体临床类风湿性关节炎的发展：针对类风湿性关节炎预防的免疫反应靶向（TIP-RA）	Prideaux, E. B.	PDF	N/A	Epigenetic trajectory predicts development of clinical rheumatoid arthritis in ACPA+ individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA)
自主神经系统（ANS）-免疫网络在人类免疫缺陷病毒（HIV）感染者中的作用	Mueller, B. R.	PDF	N/A	The Autonomic Nervous System (ANS)-Immune Network in People Living With HIV
mRNA疫苗激发并由Omicron变种回忆的B细胞纵向分析揭示了广泛中和沙贝病毒的抗体	Chen, X.	PDF	N/A	Longitudinal profiling of B cells primed by mRNA vaccine and recalled by Omicron variants uncovers antibodies broadly neutralizing sarbecoviruses
RIG-I和MDA5协同识别登革病毒（DENV）的复制形式双链RNA，从而激活先天免疫反应。	Ye, S.	PDF	N/A	RIG-I and MDA5 cooperatively recognize the DENV replicative-form dsRNA to activate innate immunity
HSV-1感染改变了MAPT剪接，并促进了阿尔茨海默病神经模型中的Tau病理	Ijezie, E. C.	PDF	N/A	HSV-1 Infection Alters MAPT Splicing and Promotes Tau Pathology in Neural Models of Alzheimer's Disease
关于噬菌体尾部终止蛋白和尾部完成蛋白：噬菌体T5尾部近端极端的结构	Linares, R.	PDF	N/A	About bacteriophage tail terminator and tail completion proteins: structure of the proximal extremity of siphophage T5 tail
耐气甲烷菌利用海藻和海草的代谢物来推动海洋甲烷的排放。	Hall, N.	PDF	N/A	Aerotolerant methanogens use seaweed and seagrass metabolites to drive marine methane emissions
TaRTLEt：利用边缘检测的转录活性核糖开关追踪器	Kshatriya, S.	PDF	N/A	TaRTLEt: Transcriptionally-active Riboswitch Tracer Leveraging Edge deTection
铜绿假单胞菌同时生产脂肽和鼠李糖脂生物表面活性剂：一种有前景的生物表面活性剂强化生物修复混合物	Jacoby, M. d. R.	PDF	N/A	Simultaneous production of lipopeptide and rhamnolipid biosurfactants by Pseudomonas aeruginosa: A promising blend for biosurfactant-enhanced bioremediation
赋予抗真菌药物抗性的RNAi表观突变是可遗传的。	Perez-Arques, C.	PDF	N/A	RNAi epimutations conferring antifungal drug resistance are inheritable
一种新型的PhoPQ增强的黏菌素耐药机制损害了铜绿假单胞菌的膜完整性	Hsieh, Y.-Y. P.	PDF	N/A	A novel PhoPQ-potentiated mechanism of colistin resistance impairs membrane integrity in Pseudomonas aeruginosa
系统注释噬菌体基因组和质粒中的超变热点	Egorov, A. A.	PDF	N/A	Systematic annotation of hyper-variability hotspots in phage genomes and plasmids
通过微血管3D血脑屏障模型揭示的恶性疟原虫出胞机制	Piatti, L.	PDF	N/A	Pathogenic mechanisms of Plasmodium falciparum egress unveiled by a microvascular 3D blood-brain barrier model
DDX3通过与PABP1及病毒基因组非翻译区的相互作用，调控日本脑炎病毒的帽依赖性翻译。	Li, C.	PDF	N/A	DDX3 regulates the cap-independent translation of the Japanese encephalitis virus via its interactions with PABP1 and the untranslated regions of the viral genome
无壁细菌的FtsZ形成环状结构	Kasai, T.	PDF	N/A	FtsZ of wall-less bacteria forms ring-like structures
单个MCP在希瓦氏菌（Shewanella putrefaciens）对浮游和结构化环境中游泳的进化适应中的作用	Edelmann, D. B.	PDF	N/A	Role of a single MCP in evolutionary adaptation of Shewanella putrefaciens for swimming in planktonic and structured environments
强烈的隔离促进了自我毁灭的合作。	Wen, L.	PDF	N/A	Strong segregation promotes self-destructive cooperation
从黄粉虫肠道中分离塑料降解微生物	Reish, H. M.	PDF	N/A	Isolation of Plastic Digesting Microbes from the Gastrointestinal Tract of Tenebrio Molitor
共生肠道病毒组通过Th17细胞调节肠道营养感应	Lin, F.	PDF	N/A	Commensal gut virome regulates intestinal nutrient sensing via Th17 cells
你是我的母亲吗？：当宿主遗传和肠道微生物在非洲化蜜蜂杂交种（Apis mellifera scutellata x sspp.）中讲述不同的系统发育故事时	Soares, K. O.	PDF	N/A	Are you my mother?: When host genetics and gut microbiota tell different phylogenetic stories in the Africanized honey bee hybrid (Apis mellifera scutellata x sspp.)
前膜和包膜蛋白对蜱传脑炎病毒结构、致病性和趋向性的影响	Rosendal, E.	PDF	N/A	The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus
丹佛动物园狮子、老虎和鬣狗群中的SARS-CoV-2疫情	Gallichotte, E. N.	PDF	N/A	SARS-CoV-2 outbreak in lions, tigers and hyenas at Denver Zoo
利用dCas引导的邻近标记技术在曲霉菌中进行位点特异性染色质蛋白质组学研究。	Strauss, J.	PDF	N/A	Locus-specific chromatin proteomics using dCas-guided proximity labelling in Aspergillus nidulans.
TropD-Detector：一种基于CRISPR/LbCas12a的系统，用于快速且灵敏地筛选恰加斯病媒介和宿主中的克氏锥虫	Ortiz-Rodriguez, L. A.	PDF	N/A	TropD-Detector: A CRISPR/LbCas12a-Based system for rapid and sensitive screening of Trypanosoma cruzi in Chagas vectors and reservoirs
一种以可重复性为重点的单细胞转录组病例对照研究的元分析方法揭示了稳健差异表达基因	Nakatsuka, N. J.	PDF	N/A	A Reproducibility Focused Meta-Analysis Method for Single-Cell Transcriptomic Case-Control Studies Uncovers Robust Differentially Expressed Genes
坏死梭杆菌和变异梭杆菌是牛生殖道微生物群中的共生成员，可能在胎儿期就定殖于牛犊体内。	Kilama, J.	PDF	N/A	Fusobacterium necrophorum and Fusobacterium varium are commensal members of the bovine reproductive microbiota and may colonize calf prenatally
多米尼加共和国非洲猪瘟主动和被动监测的最新情况	Schambow, R. A.	PDF	N/A	An Update on Active and Passive Surveillance for African Swine Fever in the Dominican Republic
铜绿假单胞菌中由RNase E支架结构域介导的关键功能和关键相互作用	Geslain, S. A. M.	PDF	N/A	Critical functions and key interactions mediated by the RNase E scaffolding domain in Pseudomonas aeruginosa
遗传兼容性和生态连通性推动抗生素抗性基因的传播	Lund, D.	PDF	N/A	Genetic compatibility and ecological connectivity drive the dissemination of antibiotic resistance genes
主要病原菌流感嗜血杆菌在局部和全球范围内经历了普遍的重组和净化选择。	MacAlasdair, N.	PDF	N/A	The major pathogen Haemophilus influenzae experiences pervasive recombination and purifying selection at local and global scales
利用单分子FRET技术对SARS-CoV-2 RNA聚合酶抑制剂的活性机制进行解析	Groves, D.	PDF	N/A	Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
活性炭通过重塑肠道微生物群的代谢来改善2型糖尿病	Zhao, C.-X.	PDF	N/A	Activated carbon ameliorates type 2 diabetes via metabolic remodeling of the gut microbiota
利用黑曲霉通过液体发酵优化甘蔗糖蜜生产柠檬酸的工艺	Amin, A.	PDF	N/A	Optimization of citric acid production from sugarcane molasses using Aspergillus niger by submerged Fermentation
基于昏迷模式的自动对焦技术在解析细菌冷休克反应期间的单细胞动力学方面展现出卓越性能	Li, S.	PDF	N/A	Coma pattern-based autofocusing unlocks superior performance in unravelling single-cell dynamics during bacterial cold shock response
RNA元件对于西尼罗河病毒诱导的核糖体移码的高效率是必需的	Aleksashin, N. A.	PDF	N/A	RNA elements required for the high efficiency of West Nile Virus-induced ribosomal frameshifting
进一步表征和工程化一个11氨基酸基序以增强重组蛋白表达	Bi, J.	PDF	N/A	Further characterization and engineering of a 11-amino acid motif for enhancing recombinant protein expression
一种流行病性Ralstonia solanacearum谱系的兴起及其宿主范围的扩展	Evseeva, D.	PDF	N/A	Emergence and host range expansion of an epidemic lineage of Ralstonia solanacearum
# BioRxiv 2024-10-15 Papers

标题	作者	PDF链接	代码仓库	Title
单细胞动态揭示了心肌细胞在应激诱导下在肥大和凋亡之间的决策	Chun, B.	PDF	N/A	Single-cell dynamics reveal a stress-induced decision between cardiomyocyte hypertrophy and apoptosis
学习增强了顶端树突中与行为相关的表征	Benezra, S. E.	PDF	N/A	Learning enhances behaviorally relevant representations in apical dendrites
弥合前庭毛细胞功能与神经声音编码之间的差距	Jaime Tobon, L. M.	PDF	N/A	Bridging the gap between presynaptic hair cell function and neural sound encoding
通过dropout增强从单细胞数据中改进基因调控网络的推断	Zhu, H.	PDF	N/A	Improved gene regulatory network inference from single cell data with dropout augmentation
SARS-CoV-2主蛋白酶对人类tRNA甲基转移酶TRMT1的识别与切割	D'Oliviera, A.	PDF	N/A	Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease
功能性连接组学揭示了小鼠视觉皮层的一般连接规则	Ding, Z.	PDF	N/A	Functional connectomics reveals general wiring rule in mouse visual cortex
前额叶皮层中感知偏见的表征	Serrano-Fernandez, L.	PDF	N/A	Representation of a Perceptual Bias in the Prefrontal Cortex
发现自足月人类胎盘的多能细胞类型	Vadakke-Madathil, S.	PDF	N/A	Discovery of a multipotent cell type from the term human placenta
研究狂犬病毒当代演化的分子钟假说	Durrant, R.	PDF	N/A	Examining the molecular clock hypothesis for the contemporary evolution of the rabies virus
核仁动力学是由核糖体有序组装所决定的。	Sheu-Gruttadauria, J.	PDF	N/A	Nucleolar dynamics are determined by the ordered assembly of the ribosome
功能性脑状态的能量与青少年起病的精神分裂症患者和健康人的认知功能相关	Theis, N.	PDF	N/A	Energy of functional brain states correlates with cognition in adolescent-onset schizophrenia and healthy persons
谷胱甘肽加速细胞周期和细胞重编程在植物再生中的作用	Lee, L. R.	PDF	N/A	Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration
ERG1A K+通道通过调节C2C12肌管中的Calsequestrin1来增加细胞内钙浓度	Hockerman, G. H.	PDF	N/A	ERG1A K+ Channel Increases Intracellular Calcium Concentration through Modulation of Calsequestrin1 in C2C12 Myotubes
CAT Bridge：一种从多组学数据中高效挖掘基因-代谢物关联的工具包	Yang, B.	PDF	N/A	CAT Bridge: an efficient toolkit for gene-metabolite association mining from multiomics Data
丘脑核团会聚核向海马CA1区的投射通过影响消退诱导的兴奋性突触分子重塑，参与了情境恐惧消退过程。	Ziolkowska, M.	PDF	N/A	Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapses
电影观看和静息状态下的结构-功能耦合与解耦：连接脑电图与结构影像的新见解	Subramani, V.	PDF	N/A	Structure-function coupling and decoupling during movie-watching and resting-state: Novel insights bridging EEG and structural imaging
单细胞测序揭示了海龙科鱼类进化适应性的发育遗传基础	Healey, H. M.	PDF	N/A	Single Cell Sequencing Provides Clues about the Developmental Genetic Basis of Evolutionary Adaptations in Syngnathid Fishes
一种良好的相互作用动力平衡引导转录因子枢纽到基因	Fallacaro, S.	PDF	N/A	A fine kinetic balance of interactions directs transcription factor hubs to genes
CRISPR-GPT：一种用于基因编辑实验自动化设计的LLM代理	Qu, Y.	PDF	N/A	CRISPR-GPT: An LLM Agent for Automated Design of Gene-Editing Experiments
基因表达随机模型中细胞核与细胞质mRNA水平的联合分布：解析结果与参数推断	Wang, Y.	PDF	N/A	Joint distribution of nuclear and cytoplasmic mRNA levels in stochastic models of gene expression: analytical results and parameter inference
移动EEG用于P3分析的预处理选择：系统文献综述与交互式探索	Jacobsen, N. S. J.	PDF	N/A	Preprocessing Choices for P3 Analyses with Mobile EEG: A Systematic Literature Review and Interactive Exploration
DNA复制过程中的模板切换是适应性基因扩增的常见来源。	Chuong, J.	PDF	N/A	Template switching during DNA replication is a prevalent source of adaptive gene amplification
一刀切不可取：一种确定远程相机陷阱实际视野范围的新方法	Carswell, B. M.	PDF	N/A	One size does not fit all: a novel approach for determining the Realised Viewshed Size for remote camera traps
使用HERRO校正的单倍型纳米孔读取进行端粒到端粒的分阶段基因组组装	Stanojevic, D.	PDF	N/A	Telomere-to-Telomere Phased Genome Assembly Using HERRO-Corrected Simplex Nanopore Reads
发条猩猩：微小RNA、体温调节权衡与脑容量进化。	Fromm, B.	PDF	N/A	Clockwork Orangutan: microRNAs, thermoregulatory tradeoffs, and the evolution of brain size.
内源性ZAP与寨卡病毒感染表型的改变相关	Le, N. P. K.	PDF	N/A	Endogenous ZAP is associated with altered Zika virus infection phenotype
通过质谱语言的语义相似性实现未知代谢物的化学空间定位与注释	Ji, H.	PDF	N/A	Chemical Space Localization for Unknown Metabolite Annotation via Semantic Similarity of Mass Spectral Language
癌症治疗期间细菌操纵子的扩展可缓解药物毒性	Trepka, K.	PDF	N/A	Expansion of a bacterial operon during cancer treatment ameliorates drug toxicity
基于能的生化振荡器分析：结合键图与线性控制理论。	Gawthrop, P.	PDF	N/A	Energy-based Analysis of Biochemical Oscillators Using Bond Graphs and Linear Control Theory.
对低温的转录反应在肠杆菌科中仅有微弱的保守性。	Hoang, J.	PDF	N/A	The transcriptional response to low temperature is weakly conserved across the Enterobacteriaceae
规模的重要性：拥有数十亿（而非数百万）参数的大型语言模型更能与自然语言的神经表征相匹配。	Hong, Z.	PDF	N/A	Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language
主观感知相似性是否属于元认知？	Moharramipour, A.	PDF	N/A	Is subjective perceptual similarity metacognitive?
果蝇造血龛通过由邻近组织和Slit-Robo信号调控的集体细胞迁移进行组装。	Nelson, K. A.	PDF	N/A	The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling
活动依赖的侧抑制使嗅球投射神经元的同步化成为可能	Dalal, T.	PDF	N/A	Activity-dependent lateral inhibition enables the synchronization of olfactory bulb projection neurons
AGS蛋白中GoLoco基序的进化修饰促进了海胆胚胎中微核的形成	Emura, N.	PDF	N/A	The evolutionary modifications of a GoLoco motif in the AGS protein facilitate micromere formation in the sea urchin embryo
翼龙尾巴舵的新软组织数据显示出复杂、动态的张力使用方式，并扩展了其进化起源。	Jagielska, N.	PDF	N/A	New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins
当前机器学习模型在预测未表征蛋白质的酶功能方面存在的局限性	de Crecy-Lagard, V.	PDF	N/A	Limitations of Current Machine-Learning Models in Predicting Enzymatic Functions for Uncharacterized Proteins
酒精通过刺激AMPK介导的对TORC1、p70/S6K和核糖体生物合成的抑制，诱导神经嵴中p53介导的细胞凋亡。	Huang, Y.	PDF	N/A	Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis.
靶向脂肪酸合酶抑制NF2/CDKN2A缺陷型恶性胸膜间皮瘤的肿瘤发展	Karnan, S.	PDF	N/A	Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma
使用泛基因组进行基因型解析的拷贝数变异分析揭示了重复基因的同源特异性全球多样性和表达分化	Ma, W.	PDF	N/A	Genotyping sequence-resolved copy-number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes
综合基因组学方法识别出酒精使用障碍个体大脑皮层的胶质细胞转录组失调及风险	Warden, A. S.	PDF	N/A	Integrative genomics approach identifies glial transcriptomic dysregulation and risk in the cortex of individuals with Alcohol Use Disorder
按需发作促进癫痫治疗药物的快速筛选	Chen, Y.	PDF	N/A	On-Demand Seizures Facilitate Rapid Screening of Therapeutics for Epilepsy
膜电位调节ERK活性和细胞增殖	Sasaki, M.	PDF	N/A	Membrane potential modulates ERK activity and cell proliferation
肥胖中肌肉类型特异性自噬信号的调节：热量限制和运动的影响	Ji, F.	PDF	N/A	Muscle Type-Specific Modulation of Autophagy Signaling in Obesity: Effects of Caloric Restriction and Exercise
高效多重非病毒工程化及多克隆γδ CAR-T细胞的扩增用于免疫治疗	Bridge, J.	PDF	N/A	Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy
对广泛同意的“瓶中基因组”项目中的一对肿瘤-正常配对样本进行了广泛测序，以开发体细胞基准。	McDaniel, J. H.	PDF	N/A	Extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair towards development of somatic benchmarks
克服突变KRAS表位翻译后修饰引起的免疫逃避，实现TCR-T细胞介导的抗肿瘤活性	Lee, J. W.	PDF	N/A	Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity
进化独特的N-糖基依赖性蛋白质质量控制系统在新型隐球菌的细胞适应性和胞外囊泡运输中发挥着关键作用	Mota, C.	PDF	N/A	Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
在斑马鱼中进行多行为表型分析，识别出一种新型非联想学习干扰因子，具有环境和人类相关性	Leuthold, D.	PDF	N/A	Multi-behavioral phenotyping in zebrafish identifies a novel disruptor of non-associative learning with environmental and human relevance
芒果苷作为转甲状腺素纤维化的潜在抑制剂	Grudinina, N.	PDF	N/A	Mangiferin As A Potential Inhibitor Of Transthyretin Fibrillogenesis
茶-1：解码生命的分子相互作用	Chai Discovery,	PDF	N/A	Chai-1: Decoding the molecular interactions of life
在一组来自狗衰老项目的多样犬种队列中，转座子的DNA甲基化模式揭示了衰老差异。	Mariner, B. L.	PDF	N/A	DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project
特定区域的扩散去极化驱动异常的癫痫后行为	Mitlasozki, B.	PDF	N/A	Region-specific spreading depolarization drives aberrant post-ictal behavior
可可碱和阿糖苷的强效抗流感协同作用	Lahiri, H.	PDF	N/A	Potent Anti-Influenza Synergistic Activity of Theobromine and Arainosine
不同皮层输入对丘脑初级和高级抑制性神经元的整合	Puzzo, C. D.	PDF	N/A	Integration of distinct cortical inputs to primary and higher order inhibitory cells of the thalamus
甲虫-真菌互利共生中共生真菌的基因组多样化	Huang, Y.-T.	PDF	N/A	Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis
RNA测序深度指南用于研究可变剪接	Tsoy, O.	PDF	N/A	RNA sequencing depth guidelines for the study of alternative splicing
人类大脑在首次使用迷幻蘑菇碱后发生变化	Lyons, T.	PDF	N/A	Human brain changes after first psilocybin use
在果蝇中进行年龄和性别特异性的线粒体-核互作测试	Garlovsky, M. D.	PDF	N/A	Testing for age- and sex- specific mitonuclear epistasis in Drosophila
活性氧解毒作用有助于脓肿分枝杆菌对抗生素的存活	Bates, N. A.	PDF	N/A	Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival
多形拟杆菌（Bacteroides thetaiotaomicron）增强沃氏嗜胆菌（Bilophila wadsworthia）中的硫化氢生成。	Davies, J.	PDF	N/A	Bacteroides thetaiotaomicron enhances H2S production in Bilophila wadsworthia
微管蛋白-2家族中的自抑制与激活的Beta-发夹机制	Webb, S.	PDF	N/A	Beta-hairpin Mechanism of Autoinhibition and Activation in the Kinesin-2 Family
体外抑制宫颈CFTR离子通道可使宫颈粘液变稠	Looney, R. J.	PDF	N/A	In vitro inhibition of the CFTR ion channel in the cervix thickens cervical mucus
通过铁死亡诱导识别靶向衰老细胞的脂质衰老剂	Zhang, L. J.	PDF	N/A	Identification of lipid senolytics targeting senescent cells through ferroptosis induction
HIF-1α 调控骨髓来源巨噬细胞的线粒体功能，但在组织驻留的肺泡巨噬细胞中则不然。	Woods, P. S.	PDF	N/A	HIF-1α regulates mitochondrial function in bone marrow-derived macrophages, but not in tissue-resident alveolar macrophages
DNA复制过程中超螺旋动态的空间组织	Kusano, Y.	PDF	N/A	Spatial organization of supercoil dynamics during DNA replication
细胞类型解析的脑溶酶体蛋白图谱鉴定出SLC45A1相关疾病为溶酶体疾病	Ghoochani, A.	PDF	N/A	Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder
可视化伴侣蛋白TRiC中β-微管蛋白折叠的成核、凝聚和传播过程	Zhao, Y.	PDF	N/A	Visualizing nucleation, condensation and propagation of β-tubulin folding in chaperonin TRiC
DIO-SPOTlight转基因小鼠用于功能性监测由整合应激反应调控的蛋白质合成	Oliver, M. L.	PDF	N/A	DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response
通过配体功能化的CRISPR-Cas9靶向个体G四链体，揭示了转录依赖的功能响应	Nuccio, S. P.	PDF	N/A	Individual G-quadruplex targeting with ligand-functionalized CRISPR-Cas9 uncovers transcriptional-dependent functional responses
TRPM8通道通过依赖于雄激素受体（AR）的Scd1基因诱导以及对不饱和脂质含量的调节，控制高尔基体的形态。	Wehbi, M.	PDF	N/A	TRPM8 channels control Golgi morphology through an AR-dependent induction of the Scd1 gene and modulation of unsaturated lipid content
多重单细胞成像揭示了在长期衰老诱导过程中，存在具有不同衰老表型的分化亚群。	Sessions, G. A.	PDF	N/A	Multiplexed single-cell imaging reveals diverging subpopulations with distinct senescence phenotypes during long-term senescence induction.
异源表达及重组伊卡鲁加霉素发酵条件的优化	Evers, J. K.	PDF	N/A	Heterologous expression and optimization of fermentation conditions for recombinant ikarugamycin production
隐私保护的大脑功能连接可视化	Tao, Y.	PDF	N/A	Privacy-Preserving Visualization of Brain Functional Connectivity
牙菌斑中含有DNase I耐受的Z-DNA和G-四链体	Evans, D. C. S.	PDF	N/A	Dental biofilms contain DNase I-resistant Z-DNA and G-quadruplexes
西南极半岛气候变化背景下的鸟类捕食者-猎物动态：范围界定综述	Russell, T. M.	PDF	N/A	Avian predator-prey dynamics in a changing climate along the Western Antarctic Peninsula; a scoping review
自动变异解读：ClinVar致病变异在不同变异注释中的不一致遗传解读	Chen, A. Y.-A.	PDF	N/A	Toward Automatic Variant Interpretation: Discordant Genetic Interpretation Across Variant Annotations for ClinVar Pathogenic Variants
NeKo：一种基于先验知识自动构建网络的工具	Ruscone, M.	PDF	N/A	NeKo: a tool for automatic network construction from prior knowledge
NeKo：一种基于先验知识自动构建网络的工具	Ruscone, M.	PDF	N/A	NeKo: a tool for automatic network construction from prior knowledge
在泛基因组图谱中高效地索引和查询注释	Novak, A. M.	PDF	N/A	Efficient indexing and querying of annotations in a pangenome graph
异常糖基化揭示了Luminal B型和高干细胞指数基底型乳腺癌队列之间意想不到的临床结果差异	Truter, M.	PDF	N/A	Aberrant glycosylation reveals unexpected clinical outcomes between Luminal B and Basal high stemness index breast cancer cohorts
无烟烟草与砷共同暴露下对口腔上皮细胞的分子和细胞表型程序的影响	Das, S.	PDF	N/A	Molecular and cell phenotype programs in oral epithelial cells directed by co-exposure to arsenic and smokeless tobacco
靶向ZNF638可激活抗病毒免疫反应，并增强胶质母细胞瘤中的免疫检查点抑制作用	Seetharam, D.	PDF	N/A	Targeting ZNF638 activates antiviral immune responses and potentiates immune checkpoint inhibition in glioblastoma
利用斑马鱼胚胎的表型观察，推进毒理学中的数据驱动分析	Michaelis, P.	PDF	N/A	Leveraging zebrafish embryo phenotypic observations to advance data-driven analyses in toxicology
无创评估交感神经和副交感神经压力反射反应的时间动态	Suarez-Roca, H.	PDF	N/A	Noninvasive Assessment of Temporal Dynamics in Sympathetic and Parasympathetic Baroreflex Responses
早引影响中的特征与信号：一项元研究	Ioannidis, J.	PDF	N/A	Features and signals in precocious citation impact: a meta-research study
口腔-肠道-脑轴中的微生物组与毒力特征影响帕金森病和认知衰退的病理生理学	Clasen, F.	PDF	N/A	Microbiome signatures of virulence in the oral-gut-brain axis influence Parkinson's disease and cognitive decline pathophysiology
巴基斯坦家禽中分离出的氟喹诺酮耐药和产超广谱β-内酰胺酶的沙门氏菌的出现	Irfan, R.	PDF	N/A	The emergence of Fluoroquinolone resistant and Extended-spectrum beta-lactamase-producing Salmonella spp. isolated from Poultry in Pakistan
自催化循环的热力学一致性	Kosc, T.	PDF	N/A	Thermodynamic consistency of autocatalytic cycles
生态时间序列中微妙的方法论差异会显著影响相关性检验结果。	Cannistra, C.	PDF	N/A	Subtle methodological variations substantially impact correlation test results in ecological time series
细胞追踪与精确误差预测	Betjes, M. A.	PDF	N/A	Cell tracking with accurate error prediction
深度学习提升人及植物组织蛋白质组中瓜氨酸化鉴定的精确度	Gabriel, W.	PDF	N/A	Deep Learning Enhances Precision of Citrullination Identification in Human and Plant Tissue Proteomes
基于统计原理的单细胞转录组特征选择	Dollinger, E.	PDF	N/A	Statistically principled feature selection for single cell transcriptomics
TE-Seq：一种转座子注释与RNA-Seq分析流程	Kelsey, M. M. G.	PDF	N/A	TE-Seq: A Transposable Element Annotation and RNA-Seq Pipeline
AlphaFold2的训练集为其预测折叠转换构象提供了动力。	Schafer, J. W.	PDF	N/A	AlphaFold2's training set powers its predictions of fold-switched conformations
综合型异构体解析的陆地棉（Gossypium barbadense）和海岛棉（Gossypium hirsutum）纤维转录组分析	Tang, J. X.	PDF	N/A	Integrated Isoform-Resolved Transcriptomic Analysis of Gossypium barbadense and Gossypium hirsutum Fibers
放射治疗在人体肺部引发促血管生成信号	Soulier, J.	PDF	N/A	Radiotherapy triggers pro-angiogenic signaling in human lung
苯肾上腺素引起的快速起始纤维化重塑和心室功能障碍涉及心肌细胞和成纤维细胞转录组的靶向重编程。	Kimball, T. H.	PDF	N/A	Rapid onset fibrotic remodeling and ventricular dysfunction induced by phenylephrine involve targeted reprogramming of myocyte and fibroblast transcriptomes
与控制番茄柱头位置相关的新数量性状基因座	Riccini, A.	PDF	N/A	New QTLs involved in the control of stigma position in tomato
进化与盗窃：Bryopsidales大型藻类和光合海蛞蝓中的状态转换丧失	Havurinne, V.	PDF	N/A	Evolution and theft: loss of state transitions in Bryopsidales macroalgae and photosynthetic sea slugs
在拟南芥细胞分裂过程中，一种与Rab-Kinesin12融合的激酶模块耦合了囊泡递送与成膜体重塑。	Elliott, L.	PDF	N/A	A Rab-Kinesin12-Fused kinase module couples vesicle delivery and phragmoplast remodelling during cytokinesis in Arabidopsis
一个全球资源约束模型，用于预测波动环境中的代谢通量动态	Yuan, H.	PDF	N/A	A global resource constrained model to predict metabolic flux dynamics in fluctuating environments
hu.MAP3.0：通过整合超过25,000个蛋白质组学实验构建的人类蛋白质复合物图谱	Fischer, S. N.	PDF	N/A	hu.MAP3.0: Atlas of human protein complexes by integration of > 25,000 proteomic experiments
酿酒酵母中复制时序的调控	Berners-Lee, R.	PDF	N/A	Regulation of replication timing in Saccharomyces cerevisiae
膝关节骨性关节炎的免疫学特征分析：调节性T细胞功能障碍作为疼痛的关键驱动因素	Binvignat, M.	PDF	N/A	Immunological Profiling in Knee Osteoarthritis: Treg Dysfunction as Key Driver of Pain
CD4+组织驻留记忆Th17细胞驱动IL-17A介导的脊柱关节炎关节病理	Liu, F.	PDF	N/A	CD4+ tissue resident memory Th17 cells drive IL-17A-mediated joint pathology in Spondyloarthritis
胆固醇硫酸盐通过局部调节免疫反应性来防止母胎冲突。	Hirotani, K.	PDF	N/A	Cholesterol sulfate prevents maternal-fetal conflict by locally modulating immune reactivity
EZH2抑制剂tazemetostat可减轻HIV免疫逃逸，减少储库形成，并促进持久的CD8+ T细胞再生。	Gramatica, A.	PDF	N/A	The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization
与全球报告的蜱传病毒相关的生态和社会经济因素	Sambado, S.	PDF	N/A	Ecological and socioeconomic factors associated with globally reported tick-borne viruses
利用DNA代谢条形码技术研究蜜蜂在整个季节的采粉模式	Larsen, S. N.	PDF	N/A	Investigating Honey Bee Pollen Foraging Patterns Across a Season Using DNA Metabarcoding
果蝇中雄性限制性选择的混合证据支持了基因内性冲突的存在。	Thyagarajan, H.	PDF	N/A	Mixed evidence for intralocus sexual conflict from male-limited selection in Drosophila melanogaster.
氨基酸替换的适应度分布定律	Sun, M.	PDF	N/A	A fitness distribution law for amino-acid replacements
预先暴露于压力可减少在严重环境扰动后社区和遗传多样性的丧失	Xu, C. C. Y.	PDF	N/A	Pre-exposure to stress reduces loss of community and genetic diversity following severe environmental disturbance
配子结合基因中的平衡多态性与人类不孕不育无关	Hart, M. W.	PDF	N/A	Balanced polymorphisms in gamete-binding genes are not associated with human infertility
小麦病原菌Zymoseptoria tritici在大陆传播过程中，其主要效应因子AvrStb6的多样化、丧失与毒力增强	Sampaio, A. M.	PDF	N/A	Diversification, loss, and virulence gains of the major effector AvrStb6 during continental spread of the wheat pathogen Zymoseptoria tritici
气味感官测试与计算机模拟预测：高分辨率量化嗅觉动态的对比	Abouelhamd, I. M. S.	PDF	N/A	Odor sensory tests vs. In-silico prediction for the high-definition quantification of olfaction dynamics
快速循环拉伸可诱导培养的人体肠平滑肌细胞产生合成性和促炎性表型，这可能改变其对相邻肠细胞的信号传递。	Wolfson, S. M.	PDF	N/A	Rapid cyclic stretching induces synthetic, proinflammatory phenotypes in cultured human intestinal smooth muscle, with the potential to alter signaling to adjacent bowel cells
一种简化的、高通量的LC-MS分析方法，用于定量细胞培养中多肽的降解情况	Rozans, S. J.	PDF	N/A	A Streamlined High-Throughput LC-MS Assay for Quantifying Peptide Degradation in Cell Culture
抗生素介导的新型纳米柱超表面阵列上的等离子共振	Waitkus, J.	PDF	N/A	Antibiotic-Mediated Plasmonic Resonance on a Novel Nanopillar Metasurface Array
植物基和动物肉类的质地剖面分析与流变学特性	Dunne, R. A.	PDF	N/A	Texture profile analysis and rheology of plant-based and animal meat
MSFragger-DDA+ 通过全隔离窗口搜索提升肽段鉴定灵敏度	Yu, F.	PDF	N/A	MSFragger-DDA+ Enhances Peptide Identification Sensitivity with Full Isolation Window Search
DecoyFinder：同源RNA序列集中污染物的鉴定	Zhu, M.	PDF	N/A	DecoyFinder: Identification of Contaminants in Sets of Homologous RNA Sequences
用于大鼠、鸡、猪和猴子单细胞及空间转录组学中细胞间通讯分析的配体-受体相互作用	Sun, Y.	PDF	N/A	Ligand-Receptor Interactions for Cell-Cell Communication Analysis in Rat, Chicken, Pig, and Monkey Single-Cell and Spatial Transcriptomics
代谢物营养图谱指南（MeNu GUIDE）——一种揭示与疾病病因相互作用的代谢物营养图谱	Wuerf, V.	PDF	N/A	MeNu GUIDE - a metabolite nutrition graph to uncover interactions with disease etiology
彗星碎片离子索引技术在增强肽段测序中的应用	McGann, C. D.	PDF	N/A	Comet fragment-ion indexing for enhanced peptide sequencing
跨物种与物种特异性模型用于蛋白质熔解温度预测	Garcia Lopez, S.	PDF	N/A	Cross-species vs species-specific models for protein melting temperature prediction
使用多阳性未标记自学习进行精确的细胞丰度定量	Lin, Y.	PDF	N/A	Accurate Cell Abundance Quantification using Multi-positive and Unlabeled Self-learning
使用空间变换的概率多序列比对	Garcia Lopez, S.	PDF	N/A	Probabilistic Multiple Sequence Alignment using Spatial Transformations
抗癌靶点组合：基于网络的信号传导方法用于发现	Yavuz, B. R.	PDF	N/A	Anticancer Target Combinations: Network-Informed Signaling-Based Approach to Discovery
SeqDance：一种用于表示蛋白质动态特性的蛋白质语言模型	Hou, C.	PDF	N/A	SeqDance: A Protein Language Model for Representing Protein Dynamic Properties
CytoLNCpred - 一种用于预测15种细胞系中胞质相关长编码RNA的计算方法	Choudhury, S.	PDF	N/A	CytoLNCpred - A computational method for predicting cytoplasm associated long-coding RNAs in 15 cell-lines
mTOR变体的激活揭示了类似PI3K的隐蔽口袋，扩展了别构、突变选择性抑制剂的设计	Liu, Y.	PDF	N/A	mTOR variants activation discovers PI3K-like cryptic pocket, expanding allosteric, mutant-selective inhibitor designs
用于预测阳离子转运的近端小管芯片：药物转运蛋白表达与功能的动态洞察	Petit, I.	PDF	N/A	Proximal Tubule-on-Chip for Predicting Cation Transport: Dynamic Insights into Drug Transporter Expression and Function
用于预测血脑屏障渗透性的注意力图神经网络模型	Collins, J. W.	PDF	N/A	Attentive graph neural network models for the prediction of blood brain barrier permeability
用于预测血脑屏障渗透性的注意力图神经网络模型	Collins, J. W.	PDF	N/A	Attentive graph neural network models for the prediction of blood brain barrier permeability
评估含有L-叔丁氨酸盐的合成大麻素受体激动剂的高效激动作用	Lucaj, C.	PDF	N/A	Assessment of high-efficacy agonism in synthetic cannabinoid receptor agonists containing l-tert-leucinate
蚜虫的热生物学及其对农业和粮食安全的意义	Villena, O. C.	PDF	N/A	Thermal biology of aphids and implications for agriculture and food security
调控小麦的棕色颖片和第一节间基因会导致木质化组织着色、木质化和抗病性的改变。	Hua, L.	PDF	N/A	Manipulation of the brown glume and internode 1 gene leads to alterations in lignified tissue coloration, lignification, and pathogen resistance in wheat
芝麻（Sesamum indicum L.）原生质体分离、培养及微愈伤组织诱导的优化	Debnath, A. J.	PDF	N/A	Optimisation of explant-specific isolation, culture, and micro-callus induction of sesame (Sesamum indicum L.) protoplasts
一种适用于GATEWAY兼容载体的新型工具箱，用于大豆复合植物中快速功能基因分析	Mejias, J.	PDF	N/A	A novel toolbox of GATEWAY-compatible vectors for rapid functional gene analysis in soybean composite plants
ABI5结合蛋白是ABA核心信号通路中关键组分的底物	Finkelstein, R. R.	PDF	N/A	ABI5 Binding Proteins are substrates of key components in the ABA core signaling pathway
红色图像：一种针对直翅目（昆虫纲）采集标本使用近红外高光谱成像（NIR-HSI）的方法论和综合方法	Tavares, G. C.	PDF	N/A	Images in red: A methodological and integrative approach for the usage of Near-infrared Hyperspectral Imaging (NIR-HSI) on collection specimens of Orthoptera (Insecta)
循环嫁接提高神经氨酸酶蛋白疫苗生产	Rijal, P.	PDF	N/A	Loop Grafting Improves Neuraminidase Protein Vaccine Production
基于Alphafold的定量方案实现跨物种MHC-II限制性表位的泛预测	Wang, S.	PDF	N/A	Pan-Prediction of MHC-II Restricted Epitopes Across Species via an Alphafold-based Quantification Scheme
外来哺乳动物破坏了本地蜣螂群落的共存关系	Akashi, R.	PDF	N/A	Invasive mammals disrupt native dung beetle community coexistence
生物相互作用和环境过滤共同决定了热带雨林中蚯蚓的α多样性和β多样性。	Goulpeau, A.	PDF	N/A	Biotic interactions and environmental filtering both determine earthworm alpha and beta diversity in tropical rainforests
佛罗里达花斑鸭在其体液先天免疫反应中表现出强烈的异质性。	Ayala, A. J.	PDF	N/A	Wild Florida Mottled Ducks demonstrate strong heterogeneity in their humoral innate immune response
卵黄莺的鸣唱和鸣叫特征	Cummings, W.	PDF	N/A	Characteristics of Vitelline Warbler songs and calls
肝脏异常对原位肝移植有重大影响。	Chen, Y.	PDF	N/A	Abnormalities of the liver have big impacts on orthotopic liver transplantation
直接巨噬细胞共培养克服粘弹性水凝胶力学，促进成纤维细胞活化	Astrab, L. R.	PDF	N/A	Direct M2 macrophage co-culture overrides viscoelastic hydrogel mechanics to promote fibroblast activation
纳米颗粒利用磁电效应来靶向并消灭癌细胞	Bryant, J. M.	PDF	N/A	Nanoparticles use magnetoelectricity to target and eradicate cancer cells
鉴定肥厚型心肌病中的新型关键基因和信号通路：基于生物信息学和下一代测序数据分析的证据	Vastrad, B. M.	PDF	N/A	Identification of novel key genes and signaling pathways in hypertrophic cardiomyopathy: evidence from bioinformatics and next generation sequencing data analysis
单分子成像中提高信噪比的革新策略：分子运动的影响	Bu, G.	PDF	N/A	Innovative Strategies for Enhancing Signal-to-Noise Ratio in Single-molecule Imaging: The Influence of Molecular Motion
细胞竞争中超竞争者的物理特征	Carpenter, L. C.	PDF	N/A	Physical traits of supercompetitors in cell competition
最优网络规模以实现最稳健的图灵模式	Ahmad Shaberi, H. S.	PDF	N/A	Optimal network sizes for most robust Turing patterns
三维点扩散函数可以在潜在空间中进行自动编码	Truedson, A.	PDF	N/A	The 3D point spread function can be autoencoded in latent space
长链非编码RNA FAM30A调控Musashi2-RUNX1轴，并在急性髓系白血病细胞中对白血病干细胞功能具有重要作用	Calvo Sanchez, J.	PDF	N/A	The long non-coding RNA FAM30A regulates the Musashi2-RUNX1 axis and is required for LSC function in AML cells
视黄酸X受体信号传导介导软脑膜中癌细胞的脂质代谢	Tong, X.	PDF	N/A	Retinoid X Receptor Signaling Mediates Cancer Cell Lipid Metabolism in the Leptomeninges
光引导的肌动蛋白聚合驱动原细胞的定向运动	Matsubayashi, H. T.	PDF	N/A	Light-guided actin polymerization drives directed motility in protocells
大多数L1CAM并不与人类生物流体和诱导多能干细胞衍生的神经元中的细胞外囊泡相关联。	Kadam, V.	PDF	N/A	Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC-derived neurons
广泛单层形成依赖于移植的人类iPSC衍生的视网膜色素上皮细胞的一个亚群	Tessmer, K.	PDF	N/A	Extensive monolayer formation depends on a subpopulation of transplanted human iPSC-derived RPE cells
猪流感中单细胞抗原受体测序	Gu, W.	PDF	N/A	Single-Cell Antigen Receptor Sequencing in Pigs with Influenza
直接对比核成像方法量化肿瘤CD8+ T细胞浸润	Sandker, G. G. W.	PDF	N/A	Head-to-head comparison of nuclear imaging approaches to quantify tumor CD8+ T-cell infiltration
EMC通过调节细胞膜流动性来促进膜蛋白的生物合成	Berraquero, M.	PDF	N/A	EMC regulates cell membrane fluidity to facilitate biogenesis of membrane proteins
校对聚合酶中的直接和间接选择	Husain, K.	PDF	N/A	Direct and indirect selection in a proofreading polymerase
稀有草原杂草残存种群间杂交优势：对恢复遗传学的启示	Oakley, C. G.	PDF	N/A	Heterosis in crosses between remnant populations of a rare prairie forb: implications for restoration genetics
印度荠菜（Rorippa indica）的种内基因组大小变异揭示了通过基因组扩大实现的热带适应性	Han, T.-S.	PDF	N/A	Intraspecific genome size variation in Rorippa indica reveals a tropical adaptation by genomic enlargement
基于机器视觉的遗传多样性小鼠脆弱性评估	Sabnis, G. S.	PDF	N/A	Machine vision based frailty assessment for genetically diverse mice
首个近乎完整的猪基因组组装：实现更准确的遗传研究	Cao, C.	PDF	N/A	The first near-complete genome assembly of pig: enabling more accurate genetic research
通过胺化作用调控明胶水凝胶界面的力学性能	Adorno, G. R.	PDF	N/A	Shaping the mechanical properties of a gelatin hydrogel interface via amination
无模型机器学习方法的3D单分子定位显微技术	Boland, M. d.	PDF	N/A	Model-free machine learning-based 3D single molecule localisation microscopy
3D超分辨率成像显示，PSD95在鼠脑中存在大量弥散的蛋白质超复合物。	Daly, S.	PDF	N/A	3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain
通过囊泡封装洞察时钟的精确性	Li, A. Z. T.	PDF	N/A	Insights into a clock's fidelity through vesicular encapsulation
突变型p53通过依赖于甲羟戊酸途径的Rho/ROCK信号传导，调控癌细胞在复杂的三维环境中的侵袭。	Guzman, A.	PDF	N/A	Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling.
肿瘤上的nsGSLs通过OT-I T细胞抑制体外抗肿瘤免疫反应，并在体内促进肿瘤生长。	Verkerk, T.	PDF	N/A	nsGSLs on tumors impair anti-tumor immune responses by OT-I T cells in vitro and support tumor growth in vivo
神经细胞系中早老素-1和早老素-2的差异表达与调控	Eccles, M. K.	PDF	N/A	Differential expression and modulation of presenilin-1 and presenilin-2 in neural cell lines
单壁碳纳米管上葡萄糖氧化酶的共价偶联用于葡萄糖传感	Wang, H.	PDF	N/A	Covalent conjugation of glucose oxidase on single-walled carbon nanotubes for glucose sensing
p62纤维的结构组织以及富含钙的p62包裹脂滴货物的细胞超微结构	Berkamp, S.	PDF	N/A	Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo
体外模型模拟肺腺癌中肿瘤内皮细胞介导的免疫细胞重编程	Krejbich, M.	PDF	N/A	In vitro models to mimic tumor endothelial cell-mediated immune cell reprogramming in lung adenocarcinoma
TGF-β诱导非典型EMT以逃避肺腺癌休眠转移中的免疫机械监视	Wang, Z.	PDF	N/A	TGF-β induces an atypical EMT to evade immune mechanosurveillance in lung adenocarcinoma dormant metastasis
单细胞和原位空间分析揭示了新生造血干细胞及其微环境的多样性	Torcq, L.	PDF	N/A	Single-cell and in situ spatial analyses reveal the diversity of newly born hematopoietic stem cells and of their niches
在克隆性下，通用型基因型和高可塑性的进化是导致蓼科植物入侵的根本原因。	Wang, S.	PDF	N/A	General purpose genotypes and evolution of higher plasticity in clonality underlie knotweed invasion
细胞形状噪声强度调控EMT相关细胞扩展过程中的形状动态	Poenisch, W.	PDF	N/A	Cell shape noise strength regulates shape dynamics during EMT-associated cell spreading
SERPINB5-TGF-β信号通路调节桥粒斑蛋白的膜定位，并改善寻常型天疱疮的皮肤水疱形成	Rathod, M.	PDF	N/A	SERPINB5-TGF-β signalling modulates desmoplakin membrane localization and ameliorates pemphigus vulgaris skin blistering
# BioRxiv 2024-10-14 Papers

标题	作者	PDF链接	代码仓库	Title
愿意等待与内源性皮质醇的变化有关。	Lukinova, E.	PDF	N/A	Willingness to wait covaries with endogenous variation in cortisol
选择性提取通过脑电图（EEG）神经模式的重现得以揭示。	Moccia, A.	PDF	N/A	Selective retrieval revealed by electroencephalographic (EEG) neural pattern reinstatement
从英国医院分离出的肠外大肠杆菌（ExPEC）菌株中的毒力因子。	Turton, J. F.	PDF	N/A	Virulence factors among isolates of extraintestinal Escherichia coli (ExPEC) from hospitals in the United Kingdom.
从非靶向代谢组学中识别和整合关键代谢反应	Köhler, N.	PDF	N/A	Identification and Integration of Key-Metabolic Reactions from Untargeted Metabolomics
人类在行走时利用了横向稳定性和机动性之间的权衡	Kulkarni, R. N.	PDF	N/A	Humans Exploit the Trade-Off Between Lateral Stability and Manoeuvrability During Walking
GEF和GAP对Cdc42 GTPase循环的寡聚依赖性和协同调控	Tschirpke, S.	PDF	N/A	Oligomerization-dependent and synergistic regulation of Cdc42 GTPase cycling by a GEF and a GAP
通过CRISPR/Cas9工程改造人类间充质干细胞系实现细胞外基质的组成性编辑	Prithiviraj, S.	PDF	N/A	Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
在伤害感受器中表达的钠通道对动作电位的阈下相、上升支和肩部有不同的贡献。	Köster, P. A.	PDF	N/A	Sodium channels expressed in nociceptors contribute distinctly to action potential subthreshold phase, upstroke and shoulder
ATP爆发是分枝杆菌抗生素致死性的主要驱动力	Lodhiya, T.	PDF	N/A	ATP burst is the dominant driver of antibiotic lethality in Mycobacteria
在观看自然电影时，神经同步性表现出韧性驱动	Ye, S.	PDF	N/A	Resilience-driven neural synchrony during naturalistic movie watching
在分化和癌症过程中，全球染色质重塑及对具有特定进化年龄基因的调控	Raynal, F.	PDF	N/A	Global chromatin reorganization and regulation of genes with specific evolutionary ages during differentiation and cancer
使用DeepScence进行单细胞和空间衰老细胞检测	Qu, Y.	PDF	N/A	Single-cell and spatial detection of senescent cells using DeepScence
植物细胞质膜桥通过内质网驱动的非完全胞质分裂形成	Li, Z. P.	PDF	N/A	Plant plasmodesmata bridges form through ER-driven incomplete cytokinesis
全脑任务调制功能连接方法在fMRI任务连接组学中的比较	Masharipov, R.	PDF	N/A	Comparison of whole-brain task-modulated functional connectivity methods for fMRI task connectomics
分子密度调控的结合位点成熟机制介导了Ndc80与着丝粒受体CENP-T的结合	Tarasovetc, E. V.	PDF	N/A	Binding Site Maturation Modulated by Molecular Density Underlies Ndc80 Binding to Kinetochore Receptor CENP-T
使用压缩光场显微镜对体内动态进行千赫兹体积成像	Wang, Z.	PDF	N/A	Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy
固有无序的RNA结合基序协同作用以催化RNA折叠并驱动相分离	Niedner-Boblenz, A.	PDF	N/A	Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation
自主唤醒的变异介导了空白思维事件的可报告性	Boulakis, P. A.	PDF	N/A	Variations of autonomic arousal mediate the reportability of mind-blanking occurrences
一种良好的相互作用动力平衡引导转录因子枢纽向基因方向移动	Fallacaro, S.	PDF	N/A	A fine kinetic balance of interactions directs transcription factor hubs to genes
在羊膜动物原肠胚形成过程中，左右组织者形成之前，双侧细胞流动呈现出不对称性。	Asai, R.	PDF	N/A	Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation
植物肉和动物肉的机械和感官特征	St. Pierre, S. R.	PDF	N/A	The mechanical and sensory signature of plant-based and animal meat
突触富集与同一神经元内两种对立多巴胺受体的动态调控	Hiramatsu, S.	PDF	N/A	Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons
多层次不可逆性揭示了人类大脑动力学中非平衡相互作用的高阶组织	Nartallo-Kaluarachchi, R.	PDF	N/A	Multilevel irreversibility reveals higher-order organisation of non-equilibrium interactions in human brain dynamics
三相血栓形成模型：B型主动脉夹层的计算研究	Gupta, I.	PDF	N/A	Triphasic Thrombosis Model: A Computational Study of Type B Aortic Dissection
蜂鸟传粉的趋同进化导致通过基因下调反复丧失花香	Darragh, K.	PDF	N/A	The convergent evolution of hummingbird pollination results in repeated floral scent loss through gene downregulation
同时捕食多个猎物：功能反应线性关系的频率和种群动态效应	Novak, M.	PDF	N/A	Feeding on multiple prey at a time:The frequency and population-dynamic effects of functional-response linearity
心脏肌钙蛋白T内源性无序连接区的结构动力学	Cubuk, J.	PDF	N/A	Structural dynamics of the intrinsically disordered linker region of cardiac troponin T
南极地热土壤中表现出缺乏区域性栖息地泛化微生物	Noell, S. E.	PDF	N/A	Antarctic geothermal soils exhibit an absence of regional habitat generalist microorganisms
一个组成性异染色质区域塑造了基因组组织并影响神经孢子菌的基因表达	Reckard, A. T.	PDF	N/A	A Constitutive Heterochromatic Region Shapes Genome Organization and Impacts Gene Expression in Neurospora crassa
利用一种新颖的纤维追踪方法，研究从婴儿期到青春期上行听觉通路微观结构成熟的空间组织	Lynch, K. M.	PDF	N/A	The spatial organization of ascending auditory pathway microstructural maturation from infancy through adolescence using a novel fiber tracking approach
鉴定枯草芽孢杆菌萌发受体蛋白GerAB中参与孢子吸水的关键残基	Chen, L.	PDF	N/A	Identification of key residues in Bacillus subtilis germinant receptor protein GerAB involved in spore water uptake
KATMAP：从敲低数据推断剪接因子活性及调控靶点	McGurk, M. P.	PDF	N/A	KATMAP: Inferring splicing factor activity and regulatory targets from knockdown data
学习进度表与教学的共同演化，不仅促进了知识的累积，还催生了一种教师创新综合症	Maisonneuve, L.	PDF	N/A	The coevolution of learning schedules and teaching enhances cumulative knowledge and drives a teacher-innovator syndrome
ATG5的非经典作用及膜ATG8化在retromer组装和功能中的作用	Paddar, M. A.	PDF	N/A	Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function
一种用于筛选体内蛋白水解开关的方法，这些开关能够介导Notch激活	Baker, F.	PDF	N/A	An in vivo screen for proteolytic switches that can mediate Notch activation
在样地和植物水平上增加植物化学多样性对节肢动物群落有影响。	Ojeda-Prieto, L.	PDF	N/A	Increasing intraspecific plant chemical diversity at plot and plant level affects arthropod communities
通过脑电图的不规则成分评估慢性疼痛中兴奋与抑制的平衡	Gil Avila, C.	PDF	N/A	Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG
力化学力调控停滞新生链的组成和命运	Khan, D.	PDF	N/A	Mechanochemical forces regulate the composition and fate of stalled nascent chains
利用光遗传学技术对肌动蛋白细胞骨架和片足形成中的膜结构进行低温电子断层扫描	Inaba, H.	PDF	N/A	Cryo-ET of actin cytoskeleton and membrane structure in lamellipodia formation using optogenetics
FusionESP：通过融合蛋白质和化学知识，提升酶-底物配对预测的改进方法	Du, Z.	PDF	N/A	FusionESP: Improved enzyme-substrate pair prediction by fusing protein and chemical knowledge
失眠评分：失眠的预测能力，对癌症具有高诊断和预后价值。	Dan, X.	PDF	N/A	Insomnia score: predictive ability of insomnia, high-diagnostic and prognostic value for cancer.
不同血清型3肺炎链球菌中转化频率与感受态基因表达的变异	Shambhu, S.	PDF	N/A	Variation in transformation frequency and competence gene expression among serotype 3 Streptococcus pneumoniae
学习是行为个体性的基本来源。	Manna, R.	PDF	N/A	Learning is a fundamental source of behavioral individuality
脑尺度：在脉冲神经网络中实现可扩展的在线学习	Wang, C.	PDF	N/A	BrainScale: Enabling Scalable Online Learning in Spiking Neural Networks
用于光刺激和电生理记录的铸造双色纳米光子神经探针	Roszko, D. A.	PDF	N/A	Foundry-fabricated dual-color nanophotonic neural probes for photostimulation and electrophysiological recording
番茄中角黄素/玉米黄质合酶的表达改变了类胡萝卜素库，增强了维生素A原和风味挥发性物质	Fu, J.	PDF	N/A	Capsanthin/Capsorubin Synthase Expression in Tomato Alters Carotenoid Pools, Enhancing Provitamin A and Flavor Volatiles
FIGL1限制了拟南芥中减数分裂非交换事件的形成	Charif, D.	PDF	N/A	FIGL1 limits the formation of meiotic non crossover events in Arabidopsis thaliana
婴儿开放大脑：一个婴儿脑部分割的开源仓库	Feczko, E. J.	PDF	N/A	Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations
E(Q)AGNN-PPIS：用于蛋白质-蛋白质相互作用位点预测的注意力增强等变图神经网络	Animesh,	PDF	N/A	E(Q)AGNN-PPIS: Attention Enhanced Equivariant Graph Neural Network for Protein-Protein Interaction Site Prediction
急性GARP耗竭会破坏囊泡运输，导致分拣、分泌和O-糖基化出现严重缺陷。	Khakurel, A.	PDF	N/A	Acute GARP depletion disrupts vesicle transport leading to severe defects in sorting, secretion, and O-glycosylation
基准测试用于抗体设计的生成模型 & 探索序列排名的对数似然性	Ucar, T.	PDF	N/A	Benchmarking Generative Models for Antibody Design & Exploring Log-Likelihood for Sequence Ranking
斑马鱼中rbfox1功能丧失导致bdnf/trkb2和pac1a表达失调，进而引起HPI轴过度激活、压力反应改变以及稳态过载。	Leggieri, A.	PDF	N/A	rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload
皮层阿尔法节律从自然场景背景中插值遮挡的运动	Yeh, L.-C.	PDF	N/A	Cortical alpha rhythms interpolate occluded motion from natural scene context
利用迁移学习预测蛋白质-小分子相互作用	Wang, J.	PDF	N/A	Leveraging Transfer Learning for Predicting Protein-Small Molecule Interactions
复杂多途径反应动力学分析：胰岛素二聚体解离	Jeong, K.	PDF	N/A	Analysis of the dynamics of a complex, multipathway reaction: Insulin dimer dissociation
预融合AAA+重塑目标-SNARE蛋白复合物促进突触传递	White, K. I.	PDF	N/A	Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission
不可或缺却又可有可无：肉桂酸4-羟化酶在水稻细胞壁木质化中的作用	Supatmi, S.	PDF	N/A	Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification
两种亚麻品种的比较分析表明木脂素介导的盐胁迫适应性	Debnath, A. J.	PDF	N/A	A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness
过去100年育种过程中小麦根系水力特性的演变	Baca Cabrera, J. C.	PDF	N/A	The evolution of root hydraulic traits in wheat over 100 years of breeding
PhenoVision：一个用于从现场图像自动化生成并交付研究就绪植物物候数据的框架	Dinnage, R.	PDF	N/A	PhenoVision: A framework for automating and delivering research-ready plant phenology data from field images
在致死温度限制以下的升高发育温度会降低埃及伊蚊的繁殖力。	Peklanska, M.	PDF	N/A	Elevated developmental temperatures below the lethal limit reduce Aedes aegypti fertility
气候和睡眠模式中的纬度梯度影响感染了绿僵菌的果蝇黑腹果蝇的疾病结果	Nan, M.	PDF	N/A	Latitudinal clines in climate and sleep patterns shape disease outcomes in Drosophila melanogaster infected by Metarhizium anisopliae
FiNNpy 2.0：快速MEG源重建	Crompton, D.	PDF	N/A	FiNNpy 2.0: Fast MEG source reconstruction
使用时间干扰正弦刺激选择性阻断C纤维传导以抑制内脏痛觉	Zhang, S.	PDF	N/A	Suppression of Visceral Nociception by Selective C-Fiber Transmission Block Using Temporal Interference Sinusoidal Stimulation
膜与皮质附着蛋白的笼蔽作用可引发细胞对称性的破坏。	Dar, S.	PDF	N/A	Caging of membrane-to-cortex attachment proteins can trigger cellular symmetry breaking
研究全氟己烷磺酸（PFHxS）对感觉运动和昼夜节律发育的影响	Ferdous, S. R.	PDF	N/A	Examining perfluorohexane sulfonate (PFHxS) impacts on sensorimotor and circadian rhythm development
FieldDino：用于植物育种研究的高通量生理形态表型分析的气孔特征	Chaplin, E. D.	PDF	N/A	FieldDino: High-throughput physio-morphological phenotyping of stomatal characteristics for plant breeding research
晚更新世气候对林地草莓基因组的影响：一种多年生草本植物的故事	Toivainen, T.	PDF	N/A	Late Quaternary climatic impact on the woodland strawberry genome: a perennial herb's tale
在芸苔属芥菜的同源多倍体中敲除脂肪酸延伸酶1同源等位基因会导致种子油中无法检测到芥酸。	Patra, N.	PDF	N/A	Knockout of fatty acid elongase1 homeoalleles in amphidiploid Brassica juncea leads to undetectable erucic acid in seed oil
非侵入性、基于生物发光的时间动态可视化和量化拟南芥中的细菌感染	Taks, N. W.	PDF	N/A	Non-invasive, bioluminescence-based visualization and quantification of bacterial infections in Arabidopsis over time
特定细菌分类群及其代谢物DHPS与阿尔茨海默病、帕金森病和肌萎缩侧索硬化症的关联。	Ellis, J. C.	PDF	N/A	Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis.
特定细菌分类群及其代谢物DHPS与阿尔茨海默病、帕金森病和肌萎缩侧索硬化症的关联。	Christopher, C. J.	PDF	N/A	Specific Bacterial Taxa and Their Metabolite, DHPS, Linked to Alzheimers Disease, Parkinsons Disease, and Amyotrophic Lateral Sclerosis.
脂肪酸延长酶eloF的调控变化是果蝇prolongata中性别特异性信息素谱系进化的基础	Yige, L.	PDF	N/A	Regulatory Changes in the Fatty Acid Elongase eloF Underlie the Evolution of Sex-specific Pheromone Profiles in Drosophila prolongata
深度相机捕捉到的产蛋母鸡在拍翅时的最大垂直高度	Grebey, T.	PDF	N/A	Maximum vertical height during wing flapping of laying hens captured with a depth camera
芬太尼强化史对多步骤决策的影响具有性别特异性	Garr, E.	PDF	N/A	Fentanyl reinforcement history has sex-specific effects on multi-step decision-making
用于即时伤口诊断的pH感应伤口敷料比色检测方法	Cherifi, K.	PDF	N/A	Colorimetric detection methods of pH-sensing wound dressing for point-of-care wound diagnostics
探索蛋白质-DNA结合残基预测及利用深度学习进行一致性可解释性分析	Liu, Y.	PDF	N/A	Exploring Protein-DNA Binding Residue Prediction and Consistent Interpretability Analysis Using Deep Learning
具有tau病理特征的特发性震颤在形态上与阿尔茨海默病和原发性年龄相关tau病变的种子无法区分。	Saez-Calveras, N.	PDF	N/A	Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy
具有tau病理特征的特发性震颤在形态上与阿尔茨海默病和原发性年龄相关tau病变的种子无法区分。	Saez-Calveras, N.	PDF	N/A	Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy
双特异性磷酸酶1（DUSP1）作为子痫前期的非侵入性循环生物标志物候选者	Andrieu, J.	PDF	N/A	Dual specificity phosphate 1 (DUSP1) as a non-invasive circulating biomarker candidate in preeclampsia
PERM1是否调节心脏收缩功能？一场数字游戏。	Zaitsev, A. V.	PDF	N/A	Does PERM1 Regulate Systolic Cardiac Function? A Game of Numbers.
列当（Orobanche cumana Wallr）控制：向日葵杂交种的可持续性研究及寄生虫防护策略	Khablak, S.	PDF	N/A	CONTROL OF OROBANCHE CUMANA WALLR: RESEARCH ON SUSTAINABILITY OF SUNFLOWER HYBRIDS AND STRATEGIES FOR PARASITE PROTECTION
人类大脑在首次使用迷幻蘑菇碱后发生变化	Lyons, T.	PDF	N/A	Human brain changes after first psilocybin use
IGF-1 影响癫痫性痉挛生成与缓解中的新皮质中间神经元连接性	Ballester-Rosado, C. J.	PDF	N/A	IGF-1 IMPACTS NEOCORTICAL INTERNEURON CONNECTIVITY IN EPILEPTIC SPASM GENERATION AND RESOLUTION
轴突特异性微管调控驱动感觉神经元轴突的不对称再生	Costa, A. C.	PDF	N/A	Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons
TGF-β1/mTORC1信号轴在定义CTHRC1+病理性成纤维细胞的转录特征中起关键作用	Wilson, J.-A. A. M.	PDF	N/A	Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts
通过加权基因相关网络和生物信息学分析鉴定糖尿病相关创伤性脑损伤的关键基因和富集生物过程	Saidu, U. F.	PDF	N/A	Identification of key genes and enriched biological processes in diabetes-associated traumatic brain injury through weighted gene correlation network and bioinformatics analysis
果蝇翅膀平面极化过程中细胞尺度信号传递的强有力证据	Carayon, A.	PDF	N/A	Evidence for strong cell-scale signalling during planar polarisation in the Drosophila wing
敲除蛋白质组学揭示USP7通过AJUBA调节结直肠癌中的细胞间粘附	Al-Eidan, A.	PDF	N/A	Knockdown proteomics reveals USP7 as a regulator of cell-cell adhesion in colorectal cancer via AJUBA
利用CRISPR条形码作为分子钟，以单细胞分辨率捕捉动态过程	Andres-Lopez, Y.	PDF	N/A	Using CRISPR barcoding as a molecular clock to capture dynamic processes at single-cell resolution
人类成肌纤维FHOD3介导的肌动蛋白延伸对于心肌细胞肌节完整性是必需的。	Valencia, D. A.	PDF	N/A	Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes
使用光学镊子对细胞力学进行稳健定量	Rodenburg, W. S.	PDF	N/A	Robust quantification of cellular mechanics using optical tweezers
胆固醇通过共同的非经典结合位点差异性地调节阿片和毒蕈碱受体的活性	Chetverikov, N.	PDF	N/A	Cholesterol differentially modulates the activity of opioid and muscarinic receptors via common non-canonical binding site
结核空洞中贝达喹啉扩散的动力学为耐药性的出现提供了契机。	Bustion, A. E.	PDF	N/A	The kinetics of bedaquiline diffusion in tuberculous cavities opens a window for emergence of resistance.
回到未来：利用多基因本地适应的环境基因组选择	Halpin-McCormick, A.	PDF	N/A	Back to the Future: Environmental genomic selection to take advantage of polygenic local adaptation
油菜黄单胞菌（Xanthomonas campestris pv. campestris）的四种细胞壁降解酶决定了细菌从排水孔逃逸到叶片脉管系统的过程。	Paauw, M.	PDF	N/A	Four cell wall-degrading enzymes of Xanthomonas campestris pv. campestris determine bacterial escape from hydathodes to the leaf vasculature
葡萄糖依赖的糖鞘脂生物合成促进CD8+ T细胞功能和肿瘤控制	Longo, J.	PDF	N/A	Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control
非协变存储效应：对放大随机适应性和人口统计波动的突变等位基因的正向选择	Kim, Y.	PDF	N/A	Noncovarying storage effect: positive selection on mutant alleles that amplify random fitness and demographic fluctuations
在检测欧洲白蜡树（Fraxinus excelsior）对白蜡枯梢病耐受性方面，临时基因分型方法的局限性	Szukala, A.	PDF	N/A	Limitations of ad hoc genotyping in detecting ash dieback tolerance in Fraxinus excelsior
人类小动脉染色质相互作用图谱揭示了血压遗传调控的新机制	Liu, Y.	PDF	N/A	Chromatin interaction maps of human arterioles reveal new mechanisms for the genetic regulation of blood pressure
CandyCollect：一种用于直接捕获和计数唾液外泌体的开放式微流控装置	Pierce, C.	PDF	N/A	CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles
CandyCollect：一种用于直接捕获和计数唾液外泌体的开放式微流控设备	Pierce, C. A.	PDF	N/A	CandyCollect: An Open-Microfluidic Device for the Direct Capture and Enumeration of Salivary-Extracellular Vesicles
半监督组学因子分析（SOFA）能够从多组学数据中分离出已知的变异源和潜在因子。	Capraz, T.	PDF	N/A	Semi-supervised Omics Factor Analysis (SOFA) disentangles known sources of variation from latent factors in multi-omics data
prolfquapp - 一个用户友好的命令行工具，简化定量蛋白质组学中的差异表达分析	Wolski, W. E.	PDF	N/A	prolfquapp - A User-Friendly Command-Line Tool Simplifying Differential Expression Analysis in Quantitative Proteomics
双途径共表达分析框架（D-CAF）能够从多组学时间序列数据中识别出新的昼夜节律调控	Chuah, J. R.	PDF	N/A	Dual-Approach Co-expression Analysis Framework (D-CAF) Enables Identification of Novel Circadian Regulation From Multi-OmicTimeseries Data
肝细胞癌中关键基因的鉴定及CDK1靶向治疗药物：生物信息学与模拟研究	Romero, R.	PDF	N/A	Identification of Hub Genes and CDK1-Targeting Therapeutics in Hepatocellular Carcinoma: Bioinformatics and Simulation Study
解读肠道微生物群对抑郁症的影响：基于社区水平的约束代谢建模方法	Yuchen, Z.	PDF	N/A	Deciphering the Gut Microbiome's Influence on Depression: A Community-Level Constraint-Based Metabolic modelling Approach
基于基因扰动从scATAC-seq数据推断基因调控网络	Shao, W.	PDF	N/A	Inferring Gene Regulatory Network Based on scATAC-seq Data with Gene Perturbation
雌激素受体1在肝星状细胞中的信号传导决定了对肝纤维化的抵抗性	Li, T.	PDF	N/A	Estrogen Receptor 1 Signaling in Hepatic Stellate Cells Designates Resistance to Liver Fibrosis
AZ12464237作为P2Y12受体的高亲和力非核苷酸拮抗剂放射性配体的表征	Steen, J.	PDF	N/A	Characterization of AZ12464237 as a high affinity, non-nucleotide antagonist radioligand for the P2Y12 receptor
利用斑马鱼快速筛选方法鉴定潜在的败血症治疗药物	Widder, M. W.	PDF	N/A	Identification of potential sepsis therapeutic drugs using a zebrafish rapid screening approach
缺乏证据表明锥状光感受器对人类夜间褪黑素抑制和警觉反应的贡献	Fazlali, F.	PDF	N/A	Lack of evidence for the contribution of cone photoreceptors to human melatonin suppression and alerting response to light at night
作为有毒环境毒物在突触核蛋白病模型中的作用	Shvachiy, L.	PDF	N/A	Lead as a toxic environmental toxicant in models of synucleinopathies
高原暴露对海平面居民骨骼肌线粒体亚细胞分布、超微结构及呼吸功能的影响	Schytz, C. T.	PDF	N/A	Effect of high-altitude exposure on skeletal muscle mitochondrial subcellular distribution, ultrastructure and respiration in sea-level residents
在发育过程中，拟南芥细胞壁的纤维网络特性被用来调节其机械性能。	Chen, S.	PDF	N/A	Mechanical properties are tuned during development with the fibrous network nature of the Arabidopsis cell wall
MMM与CLCFM：基于摄影测量的三维点云重建方法，针对单株植物旋转拍摄的全方位图像	Hayashi, A.	PDF	N/A	MMM and CLCFM: A 3D point cloud reconstruction method based on photogrammetry for all-around images taken by rotating an individual plant
使用不同LED光配方塑造羽衣甘蓝的形态和生理	Scandola, S.	PDF	N/A	Shaping Kale Morphology and Physiology Using Different LED Light Recipes
ERECTA家族信号在拟南芥胚珠起始过程中控制细胞命运的特化。	Overholt, A. M.	PDF	N/A	ERECTA family signaling controls cell fate specification during ovule initiation in Arabidopsis.
不同环境胁迫下高粱（Sorghum bicolor）蜡质层动态变化揭示了与蜡质生成相关的信号模块	Larson, M.	PDF	N/A	Wax bloom dynamics on Sorghum bicolor under different environmental stresses reveal signaling modules associated with wax production
孢粉素生物合成中的聚酮途径是陆地植物（胚胎植物）所特有的。	Suh, D.-Y.	PDF	N/A	The polyketide pathway in sporopollenin biosynthesis is specific to land plants (Embryophyta)
SOX10与微小RNA：解析它们在调控黑色素瘤可塑性中的相互作用	Lai, X.	PDF	N/A	SOX10 and microRNAs: decoding their interplay in regulating melanoma plasticity
AxSpA关节组织的特点是存在HLA-DR+组织驻留记忆（TRM）和杀伤细胞免疫球蛋白样受体（KIR）+ CD8+ T细胞亚群。	Liu, F.	PDF	N/A	AxSpA joint tissue is characterised by HLA-DR+ tissue resident memory (TRM) and killer cell immunoglobulin-like receptor (KIR)+ CD8+ T cell subsets
几丁寡糖对多微生物脓毒症的保护作用通过N-乙酰-D-葡萄糖胺残基进行了精细调节。	Patel, P.	PDF	N/A	Protection against Poly Microbial Sepsis by Chitin oligomersis fine tuned by N-Acetyl D-Glucosamine residues
多模态分析揭示CD4+CXCR5+PD-1- Tfh细胞作为人类弥漫性大B细胞淋巴瘤（DLBCL）中R-CHOP疗法反应的预后和预测生物标志物	Yu, S.	PDF	N/A	Multi-modal profiling identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers for response to R-CHOP therapy in human DLBCL
对果蝇中年龄和性别特异性线粒体-核互作的检测	Garlovsky, M. D.	PDF	N/A	Testing for age- and sex- specific mitonuclear epistasis in Drosophila
解码基因表达在不同细胞和疾病状态下的序列决定因素	Lal, A.	PDF	N/A	Decoding sequence determinants of gene expression in diverse cellular and disease states
儿童患者肺静脉狭窄的分子机制洞察	Kalustian, A. B.	PDF	N/A	Insights into the Molecular Mechanism of Pulmonary Vein Stenosis in Pediatric Patients
器官芯片设备的毒物代谢动力学	Hermann, N. G.	PDF	N/A	Toxicokinetics for organ-on-chip devices
使用加权非平行近端支持向量机的细菌菌株传播生物标志物的迁移学习模型	Ugwu, U. O.	PDF	N/A	Transfer Learning Models for Bacterial Strain Dissemination Biomarkers using Weighted Non-Parallel Proximal Support Vector Machines
微生物组知识图谱（MicrobiomeKG）：通过知识图谱连接微生物组研究与宿主健康	Goetz, S.	PDF	N/A	MicrobiomeKG: Bridging Microbiome Research and Host Health Through Knowledge Graphs
行动中的公平：四年迈向生物化学招聘中性别平等和种族多样化的旅程	Christian, S. L.	PDF	N/A	Equity in Action: A Four-Year journey towards Gender Parity and Racial Diversity in Biochemistry Hiring
自由活动小鼠的高通量双光子体积脑成像	Qian, L.	PDF	N/A	High-throughput two-photon volumetric brain imaging in freely moving mice
抑制作用解决西蒙冲突：来自脑电图解码的证据	Lee, Y. S.	PDF	N/A	Inhibition Resolves Simon Conflict: Evidence from EEG Decoding
用于研究人体神经系统环路回路的Assembloid模型	Miura, Y.	PDF	N/A	Assembloid model to study loop circuits of the human nervous system
通过高阶协方差矩阵分解实现高效的上位效应推断	Shimagaki, K. S.	PDF	N/A	Efficient epistasis inference via higher-order covariance matrix factorization
人胰腺癌中磷酸化酪氨酸突变型结蛋白的鉴定	Kendrick, N. C.	PDF	N/A	Identification of Phosphotyrosine-Mutant Desmin in Human Pancreatic Cancer
细胞内钙感知复合物CPKs/ECA1调控细胞质钙稳态以控制植物的渗透敏感性	Liang, X.	PDF	N/A	An intracellular calcium sensory complex CPKs/ECA1 controls cytosolic calcium homeostasis for plant osmosensitivity
在节肢动物中诱导白内障揭示了晶状体蛋白如何促进生物玻璃的形成	Mitra, A. T.	PDF	N/A	Cataract induction in an arthropod reveals how lens crystallins contribute to the formation of biological glass
在缺乏细胞死亡的情况下，选择性脑干神经元中的Tau负荷预测平衡缺陷的严重程度和性质。	Zhu, Y.	PDF	N/A	Tau load in select brainstem neurons predicts the severity and nature of balance deficits in the absence of cell death
丙酮酸脱氢酶激酶1调控心肌细胞中甘油三酯的水解	Atser, M. G.	PDF	N/A	Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes
未经治疗的非小细胞肺癌（NSCLC）光学成像揭示了与转移复发相关的变化	Diaz, P. M.	PDF	N/A	Optical imaging of treatment-naive human NSCLC reveals changes associated with metastatic recurrence
己糖胺生物合成途径通过改变细胞骨架来调节转移性前列腺癌中的细胞增殖和迁移。	Shakya, R.	PDF	N/A	The Hexosamine Biosynthetic Pathway alters the cytoskeleton to modulate cell proliferation and migration in metastatic prostate cancer
神经炎症与自发性高血压易中风大鼠的高血压相关脊髓病理学	Noyan, H.	PDF	N/A	Neuroinflammation and Spinal Cord Pathology Associated with Hypertension in Spontaneously Hypertensive Stroke-Prone Rats
鉴定和靶向气道上皮中调节SARS-CoV-2-宿主相互作用的因子。	Dirvin, B. G.	PDF	N/A	Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium.
卡莫氟类似物作为抗增殖剂、SARS-CoV-2主蛋白酶（Mpro）抑制剂和膜破裂诱导剂的合成与评估	Gu, T.	PDF	N/A	Synthesis and Evaluation of Carmofur Analogs as Antiproliferative Agents, Inhibitors to the Main Protease (Mpro) of SARS-CoV-2, and Membrane Rupture-Inducing Agents
基于八个协变量对COVID-19患者疾病严重程度进行预测的机器学习算法比较评估	Patel, T. S.	PDF	N/A	Comparative assessment of machine learning algorithms to predict severity of disease in COVID-19 patients based on eight cofactors
全球转录因子分析揭示了铜绿假单胞菌中调控网络的层次结构、协同作用及主要毒力调控因子	Huang, J.	PDF	N/A	Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa
改进氨基酸生物合成途径的注释：GapMind 2024	Price, M. N.	PDF	N/A	Improving the annotation of amino acid biosynthesis pathways: GapMind 2024
膜结合型鸟苷酸环化酶COP5/HKR1改变纤毛搏动模式并影响衣藻在趋化过程中的细胞转向	Strain, A. L.	PDF	N/A	Membrane-bound Guanylyl Cyclase COP5/HKR1 changes ciliary beat pattern and biases cell steering during chemotaxis in Chlamydomonas reinhardtii
农场暴露与人类母乳免疫特征和微生物群相关	Swaney, M. H.	PDF	N/A	Farm exposure is associated with human breast milk immune profile and microbiome
Cas9和雷帕霉素诱导的Cre重组酶的组成型表达促进了伯氏疟原虫中的条件性基因组编辑	Das, S.	PDF	N/A	Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei
从辣木中合成银纳米颗粒：预防SARS-CoV-2污染水的潜力	Shittu, M. O.	PDF	N/A	Green synthesized silver nanoparticles from Moringa: Potential for preventative treatment of SARS-CoV-2 contaminated water
核糖体蛋白bS1在正交mRNA起始密码子选择中的作用	Boyko, K. V.	PDF	N/A	Role of ribosomal protein bS1 in orthogonal mRNA start codon selection
氧化性RNA损伤对SARS-CoV-2依赖RNA的RNA聚合酶体外复制的影响	Akagawa, M.	PDF	N/A	Impact of an Oxidative RNA Lesion on in vitro Replication Catalyzed by SARS-CoV-2 RNA-dependent RNA Polymerase
大肠杆菌中的集体β-内酰胺耐药性：细胞死亡时释放β-内酰胺酶所致	Gross, R.	PDF	N/A	Collective β-lactam resistance in Escherichia coli due to β-lactamase release upon cell death
免疫细胞促进感染肠道病毒D68的小鼠出现瘫痪性疾病	Woods Acevedo, M. A.	PDF	N/A	Immune cells promote paralytic disease in mice infected with enterovirus D68
杀手酵母在种植真菌蚂蚁花园中的普遍存在及新型杀手毒素Ksino的发现	Bizarria, R.	PDF	N/A	The Prevalence of Killer Yeasts in the Gardens of Fungus-Growing Ants and the Discovery of Novel Killer Toxin named Ksino.
全基因组分析发现粪肠球菌中促进与卷曲乳杆菌种间竞争的基因	Lam, L. N.	PDF	N/A	Genome-wide analysis of Enterococcus faecalis genes that facilitate interspecies competition with Lactobacillus crispatus
通过mRNA展示技术支持的机器学习模型评估环脱水酶LynD的底物范围	Steude, E. G.	PDF	N/A	Assessing substrate scope of the cyclodehydratase LynD by mRNA display-enabled machine learning models
线粒体DNA突变连接Leigh综合征和颈动脉动脉粥样硬化：一项关于共享遗传途径的研究	Sharma, A.	PDF	N/A	Mitochondrial DNA Mutations Linking Leigh Syndrome and Carotid Atherosclerosis: A Study of Shared Genetic Pathways
多形拟杆菌（Bacteroides thetaiotaomicron）增强了沃氏嗜胆菌（Bilophila wadsworthia）中硫化氢的产生。	Davies, J.	PDF	N/A	Bacteroides thetaiotaomicron enhances H2S production in Bilophila wadsworthia
实时高分辨率显微镜揭示了单细胞裂解如何塑造生物膜基质形态发生	Squyres, G. R.	PDF	N/A	Real-time high-resolution microscopy reveals how single-cell lysis shapes biofilm matrix morphogenesis
香草木犀素抑制登革病毒NS5甲基转移酶的机制性见解	Bhutkar, M.	PDF	N/A	Mechanistic insights into the inhibition of dengue virus NS5 methyltransferase by herbacetin
芜菁黄花叶病毒颗粒的结构。读取通域是如何暴露在衣壳表面的？	Lai-Kee-Him, J.	PDF	N/A	Structure of the turnip yellows virus particles. How is the readthrough domain exposed on the capsid surface?
真菌病原体球孢子菌形态发育的转录组图谱揭示了关键阶段富集的转录本	Homer, C. M.	PDF	N/A	Transcriptomic atlas of the morphologic development of the fungal pathogen Coccidioides reveals key phase-enriched transcripts
细菌鉴定和感染性疾病诊断中的16S rRNA基因测序	Li, M.-N.	PDF	N/A	16S rRNA gene sequencing for bacterial identification and infectious disease diagnosis
铜绿假单胞菌金属应答TonB依赖转运蛋白的特性分析	Ferry, M.	PDF	N/A	Characterisation of Pseudomonas aeruginosas metal-responsive TonB-dependent transporters
致病性相关黏附素通过生物膜形成驱动共生菌在蜜蜂肠道中的定殖	Lariviere, P. J.	PDF	N/A	Virulence-linked adhesin drives mutualist colonization of the bee gut via biofilm formation
肝脏CYP4A自噬-溶酶体降解（ALD）：自噬受体SQSTM1/p62通过一个不常见的靶点相互作用位点发挥主要作用	He, L.	PDF	N/A	Liver CYP4A autophagic-lysosomal degradation (ALD): A major role for the autophagic receptor SQSTM1/p62 through an uncommon target interaction site
# BioRxiv 2024-10-13 Papers

标题	作者	PDF链接	代码仓库	Title
负选择可能导致转移性结直肠癌中染色体核型显著改变但总体稳定。	Cross, W.	PDF	N/A	Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer
一群多样化的顶盖前蓝斑神经元控制着觉醒和探索行为	Luskin, A. T.	PDF	N/A	A diverse population of pericoerulear neurons controls arousal and exploratory behaviors
神经-GSTH：一种几何散射与持久同源性框架，用于揭示神经活动中的时空特征	Bhaskar, D.	PDF	N/A	Neuro-GSTH: A Geometric Scattering and Persistent Homology Framework for Uncovering Spatiotemporal Signatures in Neural Activity
成纤维细胞网络是毛囊再生中不可或缺的干细胞龛组成部分。	Canella, M.	PDF	N/A	Telocyte networks are an essential stem cell niche component in hair follicle regeneration
化学熵的动能与能量牵引	Baker, J.	PDF	N/A	The Kinetic and Energetic Pull of Chemical Entropy
MpmiR319促进苔藓植物小立碗藓（Marchantia polymorpha）中珠芽/珠芽杯的形成。	Futagami, K.	PDF	N/A	MpmiR319 promotes gemma/gemma cup formation in the Liverwort Marchantia polymorpha
reconcILS：一种允许不完全谱系分选的基因树-物种树比对算法	Mishra, S.	PDF	N/A	reconcILS: A gene tree-species tree reconciliation algorithm that allows for incomplete lineage sorting
IIHP：阻塞性睡眠呼吸暂停中的智能高血压事件预测	Halimi Milani, O.	PDF	N/A	IIHP: Intelligent Incident Hypertension Prediction in Obstructive Sleep Apnea
量子热力学、嵌套共振结构与生命的熵稳定性	Baker, J.	PDF	N/A	Quantized Thermodynamics, Nested Resonant Structures, and the Entropic Stability of Life
细胞死亡的理论基础	Himeoka, Y.	PDF	N/A	A theoretical basis for cell death
目标简化与循环消除加速强化学习并模拟人类大脑在目标导向学习中的活动	Cheng, H.	PDF	N/A	Goal Reduction with Loop-Removal Accelerates RL and Models Human Brain Activity in Goal-Directed Learning
星形胶质细胞吞噬作用对皮层纹状体突触的选择性调控	Kim, J.-y.	PDF	N/A	Selective regulation of corticostriatal synapses by astrocytic phagocytosis
目标距离视觉视野和年龄增长影响视觉搜索效率：行为和建模证据	Akbari, F.	PDF	N/A	Target Distance from the Visual Field and Increased Age Affect Visual Search Efficiency: Behavioral and Modeling Evidence
果蝇EcR-Hippo组分Taiman通过调控Dally样糖蛋白和Wg梯度促进上皮细胞适应性	Schweibenz, C. K.	PDF	N/A	The Drosophila EcR-Hippo component Taiman promotes epithelial cell fitness by control of the Dally-like glypican and Wg gradient
营养状态依赖的果蝇胰岛素产生细胞的调节	Singh Bisen, R.	PDF	N/A	Nutritional state-dependent modulation of Insulin-Producing Cells in Drosophila
氟康唑抗性在耳念珠菌III株中的短期进化和传播模式	Cancino-Munoz, I.	PDF	N/A	Short-Term Evolution and Dispersal Patterns of fluconazole-resistance in Candida auris clade III
鉴定牛奶过敏发展的潜在炎症标志物	Hendrickx, D. M.	PDF	N/A	Identification of potential inflammation markers for outgrowth of cow's milk allergy
疟原虫需要一种不同的血红素加氧酶来促进顶复合物基因的表达和生物发生。	Blackwell, A. M.	PDF	N/A	Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis
RNADiffFold：使用离散扩散模型进行RNA二级结构预测的生成方法	Wang, Z.	PDF	N/A	RNADiffFold: Generative RNA Secondary Structure Prediction using Discrete Diffusion Models
肥胖者体内胰岛素对血浆脂质提取及其向肌肉外分流的抑制作用受损	Katsanos, C. S.	PDF	N/A	Impaired Suppression of Plasma Lipid Extraction and its Partitioning Away from Muscle by Insulin in Humans with Obesity
多步生物合成途径的双重诱导控制系统	Rincon, A. F. C.	PDF	N/A	A dual-inducible control system for multistep biosynthetic pathways
通过原子分解的突发估计（BEAD）：用于在脑信号中寻找振荡突发的工具箱	Anand, A.	PDF	N/A	Burst Estimation through Atomic Decomposition (BEAD): A Toolbox to find Oscillatory Bursts in Brain Signals
快速眼动睡眠期间的心率变异性与减少的负面记忆偏差相关	Morehouse, A. B.	PDF	N/A	Heart Rate Variability During Rapid Eye Movement Sleep is Associated with Reduced Negative Memory Bias
衰老小鼠各组织中的自噬作用	Carosi, J. M.	PDF	N/A	Autophagy across tissues of aging mice
亲代照料对毒蛙皮肤微生物群落组成的影响	Fischer, M.-T.	PDF	N/A	Effects of parental care on skin microbial community composition in poison frogs
独立推导预测药物诱发尖端扭转型室性心动过速的异位轴	Heitmann, S.	PDF	N/A	Independent derivations of the axis of arrhythmia for predicting drug-induced torsades de pointes
人类积极地重构神经任务状态	Ritz, H.	PDF	N/A	Humans actively reconfigure neural task states
人类积极地重构神经任务状态	Ritz, H.	PDF	N/A	Humans actively reconfigure neural task states
冷冻电镜展示了驱动蛋白激活途径的多个步骤	Kendrick, A.	PDF	N/A	Cryo-EM visualizes multiple steps of dynein activation pathway
在运动规划中高效编码	Wang, T.	PDF	N/A	Efficient Coding in Motor Planning
使用自动编码器生成信号和ResNet分类的脑刺激伪影鲁棒检测	Saal, J.	PDF	N/A	Robust Detection of Brain Stimulation Artifacts in iEEG Using Autoencoder-Generated Signals and ResNet Classification
通过拓扑高阶功能连接解析精神分裂症中的整合-分离失衡	Li, Q.	PDF	N/A	Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity
减少覆盖范围的空间异质性可以提高狗类狂犬病疫苗接种的有效性。	Ferguson, E.	PDF	N/A	Reducing spatial heterogeneity in coverage improves the effectiveness of dog vaccination against rabies
GPR87在肺纤维化中的作用	Khoury, J.	PDF	N/A	The role of GPR87 in Pulmonary Fibrosis
胞外谷胱甘肽的分解代谢为肿瘤生长提供了氨基酸支持。	Hecht, F.	PDF	N/A	Catabolism of extracellular glutathione supplies amino acids to support tumor growth
一种结直肠癌中三级淋巴结构数字表征的新方法	Munoz-Erazo, L.	PDF	N/A	A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer
系统挖掘肠道微生物组生物标志物用于炎症性肠病	Zhang, Y.	PDF	N/A	Systematic Mining of gut microbiota biomarkers for IBD
公开的RNA测序数据并不能代表全球人类的多样性。	Gallego Romero, I.	PDF	N/A	Public RNA-seq data are not representative of global human diversity
脑部预靶向PET：利用单克隆抗体成像中枢神经系统靶点的新视野	Gustavsson, T.	PDF	N/A	Brain Pretargeted PET; New Horizons to Image CNS Targets with Monoclonal Antibodies
持续性钠电流将癫痫与Scn8a功能获得性小鼠中的扩散性去极化耦合	Aiba, I.	PDF	N/A	Persistent Na+ current couples seizure with spreading depolarization in Scn8a gain of function mice
数据驱动的图像分析用于确定抗体诱导的细胞间粘附解离及抗体在寻常型天疱疮中的病原性	Moghaddam, A. O.	PDF	N/A	Data-Driven Image Analysis to Determine Antibody-Induced Dissociation of Cell-Cell Adhesion and Antibody Pathogenicity in Pemphigus Vulgaris
活跃的RNA合成模式核凝聚物	Banani, S. F.	PDF	N/A	Active RNA synthesis patterns nuclear condensates
腹侧纹状体与显著网络具有优先关联，包括背外侧前额叶皮层中的区域。	Kosakowski, H. L.	PDF	N/A	Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex
可可碱和阿糖腺苷的强效抗流感协同作用	Lahiri, H.	PDF	N/A	Potent Anti-Influenza Synergistic Activity of Theobromine and Arainosine
习惯形成的计算原理	Lakshminarasimhan, K. J.	PDF	N/A	A computational principle of habit formation
DNA聚合酶η受到相互排斥的单泛素化和单NEDD化调控。	Moreno, N. C.	PDF	N/A	DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation
生物学中的弱磁场效应是可以测量的——在没有地磁场的情况下，爪蟾胚胎发育会加速。	Lodesani, A.	PDF	N/A	Weak magnetic field effects in biology are measurable--accelerated Xenopus embryogenesis in the absence of the geomagnetic field
从生物物理模型和保存的标本中可靠地重建蟋蟀鸣声	Weiner, R. J.	PDF	N/A	Reliable reconstruction of cricket song from biophysical models and preserved specimens
从生物物理模型和保存的标本中可靠地重建蟋蟀鸣声	Weiner, R. J.	PDF	N/A	Reliable reconstruction of cricket song from biophysical models and preserved specimens
直接计算评估粘着斑蛋白-肌动蛋白解离动力学揭示了抓附键行为	Ccoa, W. J. P.	PDF	N/A	A direct computational assessment of vinculin-actin unbinding kinetics reveals catch bonding behavior
弓形虫引发的侵袭孔	Kegawa, Y.	PDF	N/A	The invasion pore induced by Toxoplasma gondii
治疗前后肿瘤内遗传异质性模式	Stein, A.	PDF	N/A	On the patterns of genetic intra-tumour heterogeneity before and after treatment
在光捕获调节下活体衣藻细胞的时间-空间分辨荧光光谱	Fujita, Y.	PDF	N/A	Time- Space Resolved Fluorescence Spectroscopy in Live Chlamydomonas Cells under Light-Harvesting Regulation
ExoSloNano：用于活细胞和冷冻电子断层扫描中大分子识别的多模态纳米金标签	Young, L. N.	PDF	N/A	ExoSloNano: Multi-Modal Nanogold Tags for identi-fication of Macromolecules in Live Cells & Cryo-Electron Tomograms
数据驱动方程自由动力学应用于多蛋白质复合物：微管尖端松弛	Wu, J.	PDF	N/A	Data-Driven Equation-Free Dynamics Applied to Many-Protein Complexes: The Microtubule Tip Relaxation
病原性螺旋体中乙酸激酶（AckA）在乙酸生成途径中的作用的生物物理和生化证据	Deka, R.	PDF	N/A	Biophysical and biochemical evidence for the role of acetate kinases (AckAs) in an acetogenic pathway in pathogenic spirochetes
连接的染色质放大了乙酰化调控的核小体相互作用	Li, R.	PDF	N/A	Connected Chromatin Amplifies Acetylation-modulated Nucleosome Interactions
用于临床前高场fMRI的非对称自旋回波多回波回波平面成像（ASEME-EPI）序列	Johnson, K. A.	PDF	N/A	Asymmetric spin echo multi-echo echo planar imaging (ASEME-EPI) sequence for pre-clinical high-field fMRI
艾伦人脑图谱的主题建模分析	Pizzini, L.	PDF	N/A	Topic Modeling analysis of the Allen Human Brain Atlas
鉴定人类长寿者中IGF-1基因的功能性罕见编码变异	Ali, A.	PDF	N/A	Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity
序列和结构对RNA中吡咯胞嘧啶荧光的影响	Coulson, T. L.	PDF	N/A	Impacts of sequence and structure on pyrrolocytosine fluorescence in RNA
特征选择增强了针对TCR特异性相互作用的肽结合预测	Teimouri, H.	PDF	N/A	Feature Selection Enhances Peptide Binding Predictions for TCR-Specific Interactions
HEXIM1同源二聚体结合7SK RNA上的两个位点，以解除对P-TEFb失活的自身抑制作用。	Yang, Y.	PDF	N/A	HEXIM1 homodimer binds two sites on 7SK RNA to release autoinhibition for P-TEFb inactivation
窦房结细胞中Ryanodine受体簇网络的结构-功能关系	Maltsev, A. V.	PDF	N/A	Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells
一种不依赖于软件的指标，用于估算单分子在任何定位显微超分辨率实验中的实验定位精度	Brenlla-Lopez, A.	PDF	N/A	A software-independent metric to estimate the experimental localization precision of single molecules in any localization microscopy super-resolution experiment
整合到丘脑初级和高级抑制性神经元的不同皮层输入	Puzzo, C. D.	PDF	N/A	Integration of distinct cortical inputs to primary and higher order inhibitory cells of the thalamus
冷冻电子断层扫描揭示了黄病毒复制、出芽和成熟的耦合过程	Dahmane, S.	PDF	N/A	Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation
新型相关显微技术用于纳米生物界面研究：超细颗粒物诱导肺上皮细胞损伤	Podlipec, R.	PDF	N/A	Novel correlative microscopy approach for nano-bio interface studies of ultrafine particle-induced lung epithelial cell damage
同种异体脂肪来源的基质细胞能够调节免疫反应，但在C57BL/6小鼠的去细胞化脂肪组织植入物中的持久性有限。	Walker, J. T.	PDF	N/A	Syngeneic adipose-derived stromal cells modulate the immune response but have limited persistence within decellularized adipose tissue implants in C57BL/6 mice
剖析复杂基因组物种中整个氨基酸转运蛋白家族的营养调控：化弱点为优势的整体方法	Le Garrec, S.	PDF	N/A	Dissecting the nutritional regulations of a whole amino acid transporter family from a complex genome species: A holistic approach turning weaknesses into strengths
衣被蛋白复合体I对于登革病毒非结构蛋白1的高效分泌是必需的。	Johnson, S.	PDF	N/A	Coatomer protein complex I is required for efficient secretion of dengue virus non-structural protein 1
哺乳动物细胞间活体内mRNA运输的证据	Shubin, A.	PDF	N/A	Evidence for in vivo mRNA Transport Between Mammalian Cells
中性脂质在彗星试验中限制断裂DNA分子的移动性	Soulet, C.	PDF	N/A	Neutral lipids restrict the mobility of broken DNA molecules during comet assays
神经肽aCGRP损害了软骨细胞对机械负荷的反应。	Dietmar, H. F.	PDF	N/A	The neuropeptide aCGRP impairs the chondrocyte response to mechanical load
物种特异性卫星DNA组成决定了PRC1介导的着丝粒异染色质的从头形成	Lamelza, P.	PDF	N/A	Species-specific satellite DNA composition dictates de novo formation of PRC1-mediated pericentric heterochromatin
静息细胞再进入受到巨自噬诱导的溶酶体损伤的限制	Murley, A.	PDF	N/A	Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage
通过直接外泌体转染高效地将小RNA递送至体外足细胞。	Lange, T.	PDF	N/A	Efficient delivery of small RNAs to podocytes in vitro by direct exosome transfection.
RNA聚合酶II是前进的DNA复制叉的极性路障。	Kay, T. M.	PDF	N/A	RNA Polymerase II is a Polar Roadblock to a Progressing DNA Fork
基于mRNA的流感疫苗扩大了人类B细胞反应的广度	Matz, H. C.	PDF	N/A	mRNA-based influenza vaccine expands breadth of B cell response in humans
高效细胞凋亡诱导：通过生物素或DNA寡聚体结合域修饰的异亮氨酸拉链改性CD95配体的高产纯化	Shang, X.	PDF	N/A	High yield purification of an Isoleucine zipper modified CD95 Ligand with either biotin or DNA-oligomer binding domain for efficient Cell Apoptosis Induction
通过可逆的YAP介导的细胞周期蛋白D1/p27比率增加引起的短暂增殖	Ferrick, K. R.	PDF	N/A	Transient proliferation by reversible YAP-mediated increase of the cyclin D1/p27 ratio
PDGF-AB/BB对人类椎间盘细胞衰老的保护作用	Zhang, C.	PDF	N/A	Protective effects of PDGF-AB/BB against cellular senescence in human intervertebral disc
miR126介导的Rett综合征中血管完整性受损	Osaki, T.	PDF	N/A	miR126-mediated impaired vascular integrity in Rett syndrome
加载激活的FGFR和beta1整合素靶向不同的软骨细胞机械应答基因	Dietmar, H. F.	PDF	N/A	Load activated FGFR and beta1 integrins target distinct chondrocyte mechano-response genes
α微管蛋白序列在氨基酸水平上的差异对减数分裂具有独特的要求。	Chen, L.	PDF	N/A	Amino acid-level differences in alpha tubulin sequences are uniquely required for meiosis
氨基酸通过溶酶体定位增强mTOR激活的协同作用	Kolaczkowski, O. M.	PDF	N/A	Synergistic Role of Amino Acids in Enhancing mTOR Activation Through Lysosome Positioning
多成分营养补充剂与衰老小鼠的衰老干预具有可比的抗衰老功效	Brookes, C.	PDF	N/A	Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice
神经相关巨噬细胞调控脂肪稳态贯穿生命周期，并抑制与年龄相关的炎症	Gonzalez-Hurtado, E.	PDF	N/A	Nerve-associated macrophages control adipose homeostasis across lifespan and restrain age-related inflammation
DeepPaint：一个用于细胞成像图像分类的深度学习包	Luna, D.	PDF	N/A	DeepPaint: A deep-learning package for Cell Painting Image Classification
解码空间组织结构：一种用于多重成像分析的可扩展贝叶斯主题模型	Peng, X.	PDF	N/A	Decoding Spatial Tissue Architecture: A Scalable Bayesian Topic Model for Multiplexed Imaging Analysis
渗透压调节影响微塑料在淡水和海洋环境中对鱼类的消除作用。	Pratiwi, H. M.	PDF	N/A	Osmoregulation affects elimination of microplastics in fish in freshwater and marine environments
必需却非不可或缺：肉桂酸4-羟化酶在水稻细胞壁木质化中的作用	Lam, L. P. Y.	PDF	N/A	Essential Yet Dispensable: The Role of CINNAMATE 4-HYDROXYLASE in Rice Cell Wall Lignification
寄生植物列当（Orobanche cumana Wallr.）对向日葵根细胞的半活体营养感染	Khablak, S.	PDF	N/A	HEMIBIOTROPHIC INFECTION OF SUNFLOWER ROOT CELLS BY THE PARASITE OROBANCHE CUMANA WALLR.
推断人类睾丸中细胞类型内和细胞类型间的转录后调控	Khan, S.	PDF	N/A	Inferring post-transcriptional regulation within and across cell types in human testis
自然杀伤细胞介导了静脉注射卡介苗对小鼠肺转移的预防功效。	Guerrero, C.	PDF	N/A	NK cells mediate preventive efficacy of intravenous BCG against lung metastasis in mice
营养物质添加对疾病的放大作用：从个体到群落水平的机制测试	Green, E. T.	PDF	N/A	Amplification of disease by nutrient addition: Testing mechanisms from individual to community levels
雄性二型性与出现策略：一种关于Fabriciana nerippe Felder, 1862中雄性先熟的数学模型	Kubo, H.	PDF	N/A	Male Dimorphism and Emergence Strategies: A Mathematical Model of Protandry in Fabriciana nerippe Felder, 1862
附口桡足类寄生虫Salmincola markewitschi通过降低宿主摄食活动，减少了幼年鲑科鱼类Salvelinus leucomaenis的体质状况和生长：寄生虫移除实验的证据	Murakami, L.	PDF	N/A	Mouth-attaching copepod Salmincola markewitschi reduces the body condition and growth of juvenile salmonid Salvelinus leucomaenis by decreasing host feeding activity: evidence from parasite removal experiment
古基因组学揭示了阿塔卡马沙漠早期游牧社会中的驯养骆驼科动物放牧和野生骆驼科动物狩猎活动。	O'Hare, C.	PDF	N/A	Paleogenomics unveil domesticated camelid herding and wild camelid hunting in early pastoralist societies in the Atacama Desert
来自伊比利亚东部的中世纪基因组揭示了摩里斯科人大规模驱逐在拆除与北非长期存在的遗传桥梁中的作用	Oteo-Garcia, G.	PDF	N/A	Medieval genomes from eastern Iberia illuminate the role of Morisco mass deportations in dismantling a long-standing genetic bridge with North Africa
通过高分辨率3D染色质相互作用解析心脏疾病GWAS调控非编码位点，揭示与心力衰竭病理生理相关的因果基因	Gill, R.	PDF	N/A	Dissecting Regulatory Non-Coding Heart Disease GWAS Loci with High-Resolution 3D Chromatin Interactions Reveals Causal Genes with Pathophysiological Relevance to Heart Failure
创伤后骨关节炎的时间依赖性计算模型，用于估计机械炎症机制如何影响软骨聚集蛋白聚糖含量	Eskelinen, A. S. A.	PDF	N/A	Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content
对25份普通小麦亚基因组间转录组变异的建模揭示了顺式和反式调控结构	Nomura, Y.	PDF	N/A	Modeling of transcriptomic variation among subgenomes in 25 accessions of common wheat reveals cis- and trans-regulation architectures
可扩展的代谢途径枚举与采样方法，适用于生物体与生态群落	Oyas, O.	PDF	N/A	Scalable enumeration and sampling of minimal metabolic pathways for organisms and communities
MMP21作为一种流体流动传递的形态发生素，在发育过程中赋予生物体左右不对称性。	Ott, T.	PDF	N/A	MMP21 behaves as a fluid flow transported morphogen to impart laterality during development
最近在黑腹果蝇谱系中出现了密码子偏好的逆转	Yamashita, H.	PDF	N/A	Recent codon preference reversals in the Drosophila melanogaster lineage
粒细胞集落刺激因子通过依赖I型干扰素的方式，对抗关节炎性阿尔法病毒的发病机制。	Hameed, M.	PDF	N/A	Granulocyte colony-stimulating factor protects against arthritogenic alphavirus pathogenesis in a type I IFN-dependent manner
冰川消退后，全浮游栉水母Mnemiopsis的快速物种形成	Ketchum, R. N.	PDF	N/A	Rapid speciation in the holopelagic ctenophore Mnemiopsis following glacial recession
宿主物种对多种病毒易感性的正相关性	Imrie, R. M.	PDF	N/A	Positive correlations in susceptibility to a diverse panel of viruses across host species
使用AnnDictionary对大型语言模型进行细胞类型注释的基准测试	Crowley, G.	PDF	N/A	Benchmarking Cell Type Annotation by Large Language Models with AnnDictionary
大型丝氨酸整合酶脱靶发现与深度学习用于全基因组预测	Bakalar, M. H.	PDF	N/A	Large Serine Integrase Off-Target Discovery with Deep Learning for Genome Wide Prediction
通过基因集嵌入揭示潜在的生物功能关联	Huang, Y.	PDF	N/A	Uncovering Latent Biological Function Associations through Gene Set Embeddings
Argonaute功能的结构和进化决定因素	Wallmann, A.	PDF	N/A	Structural and evolutionary determinants of Argonaute function
少量错误组装可能会对基于泛基因组的宏基因组分析产生不成比例的影响。	Majernik, S. N.	PDF	N/A	Small amounts of misassembly can have disproportionate effects on pangenome-based metagenomic analyses
Ephrin-A2和磷酸抗原介导的γδT细胞选择性杀伤髓母细胞瘤，同时保留神经元和干细胞的完整性	Boutin, L.	PDF	N/A	Ephrin-A2 and Phosphoantigen-Mediated Selective Killing of Medulloblastoma by γδT Cells Preserves Neuronal and Stem Cell Integrity
探索通过合成生物学生产的异贝壳杉烯酸的药理潜力	Pimentel, L. L.	PDF	N/A	Exploring the Pharmacological Potential of Kaurenoic Acid Produced via Synthetic Biology
从萝芙木中鉴定潜在的多巴胺受体D2拮抗剂：一种基于计算机的虚拟筛选方法	Chakraborty, S.	PDF	N/A	Identifying potential dopamine receptor D2 antagonist from Rauwolfia serpentina An in-silico virtual screening approach
两种亚麻品种的比较分析表明，木脂素介导的盐胁迫适应性	Debnath, A. J.	PDF	N/A	A comparative analysis between two flax varieties indicates lignan-mediated salt stress adaptiveness
过去100年间小麦根系水力特性的演变	Baca Cabrera, J. C.	PDF	N/A	The evolution of root hydraulic traits in wheat over 100 years of breeding
甲基对羟基苯甲酸酯抑制果蝇病原菌铜绿假单胞菌的毒力和传播能力	Henry, Y.	PDF	N/A	Methylparaben dampens virulence and transmissibility of the Drosophila pathogen Pseudomonas entomophila
单细胞转录组分析揭示了肥胖相关免疫细胞动力学在阿尔法病毒感染期间的变化	Hameed, M.	PDF	N/A	Obesity-Associated Changes in Immune Cell Dynamics During Alphavirus Infection Revealed by Single Cell Transcriptomic Analysis
直接和间接的RANK配体及CD40配体信号调控成年胸腺中胸腺上皮细胞频率和特性的维持	Hayama, M.	PDF	N/A	Direct and indirect RANK ligand and CD40 ligand signaling regulate the maintenance of thymic epithelial cell frequency and properties in the adult thymus
转录因子PU.1的抑制通过CXCL9-CXCR3轴促进细胞毒性淋巴细胞的招募，从而抑制小鼠肿瘤生长。	Sleapnicov, N.	PDF	N/A	Inhibition of the transcription factor PU.1 suppresses tumor growth in mice by promoting the recruitment of cytotoxic lymphocytes through the CXCL9-CXCR3 axis
细胞酶和表没食子儿茶素-3-没食子酸酯作为抗生素疗效增强剂在多微生物生物膜治疗中的研究	Murray, O.	PDF	N/A	An Investigation of Cellulase and Epigallocatechin-3-gallate as Enhancers of Antibiotic Efficacy in Polymicrobial Biofilm Treatments
非经典糖蛋白H复合物增强巨细胞病毒进入	Norris, M. J.	PDF	N/A	A noncanonical glycoprotein H complex enhances cytomegalovirus entry
SUMO化以一种基因组上下文特异性的方式，差异性地调控SMCHD1复合体的形成及其功能	Goossens, R.	PDF	N/A	SUMOylation differentially regulates SMCHD1 complex formation and function in a genomic context-specific manner
一类类似于Tn7的转座子家族进化出了针对CRISPR重复序列的能力。	Chacon Machado, L.	PDF	N/A	A family of Tn7-like transposons evolved to target CRISPR repeats
启动子和增强子依赖的凝聚蛋白加载启动染色体环化，以折叠Tcrb位点进行长程重组	Bassing, C.	PDF	N/A	Promoter- and Enhancer-Dependent Cohesin Loading Initiates Chromosome Looping to Fold Tcrb Loci for Long-Range Recombination
从雄性骨骼肌中分离出的线粒体含有一组独特的miRNA，这些miRNA在急性运动后表现出差异表达。	Silver, J.	PDF	N/A	Mitochondria isolated from male skeletal muscle contain a distinct 1 population of miRNA that are differentially expressed following acute exercise
急性与慢性农药暴露在熊蜂大脑中引发根本不同的分子反应	Witwicka, A.	PDF	N/A	Acute and chronic pesticide exposure trigger fundamentally different molecular responses in bumble bee brains
自然浮游生物群落中的生物多样性预测揭示了温度和生物相互作用作为关键预测因素	Merz, E.	PDF	N/A	Biodiversity forecasting in natural plankton communities reveals temperature and biotic interactions as key predictors
比较单细胞分析揭示了蝙蝠翅膀发育中保守基因程序的进化再利用	Schindler, M.	PDF	N/A	Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene program in bat wing development
人口基因组学揭示了在没有清除的情况下遗传漂移的强烈影响，并指导了巨藻和巨藻的保护	Bemmels, J. B.	PDF	N/A	Population genomics reveals strong impacts of genetic drift without purging and guides conservation of bull and giant kelp
人类大脑转录组中性别偏好的早期确立与生命历程稳定性	Benoit-Pilven, C.	PDF	N/A	Early establishment and life course stability of sex biases in the human brain transcriptome
在多发性骨髓瘤患者中，基因表达和预后结果受到生殖系和体细胞遗传效应的影响。	Natri, H. M.	PDF	N/A	Germline and somatic genetic effects on gene expression and outcome in patients with Multiple Myeloma
利用自适应采样对儿童急性白血病进行实时基因组特征分析	Geyer, J.	PDF	N/A	Real-time genomic characterization of pediatric acute leukemia using adaptive sampling
哺乳动物基因组中独特区域的检测与注释	Vieira Mourato, B.	PDF	N/A	Detection and Annotation of Unique Regions in Mammalian Genomes
泛基因组揭示了基因内容变异和结构变异对猪特征的影响	Du, H.	PDF	N/A	Pangenome Reveals Gene Content Variations and Structural Variants Contributing to Pig Characteristics
高分辨率全基因组染色质可及性和扭转应力图谱分析	Hall, P. M.	PDF	N/A	High-Resolution Genome-Wide Mapping of Chromatin Accessibility and Torsional Stress
一套基础模型捕捉到了密码子之间的上下文相互作用	Naghipourfar, M.	PDF	N/A	A Suite of Foundation Models Captures the Contextual Interplay Between Codons
保留隐藏的层次结构：用于增强基因组序列分析的庞加莱距离	Ali, S.	PDF	N/A	Preserving Hidden Hierarchical Structure: Poincare Distance for Enhanced Genomic Sequence Analysis
一种从烟草（Nicotiana benthamiana）中纯化用于结构研究的重组蛋白的多功能协议	Lawson, A. W.	PDF	N/A	A versatile protocol for purifying recombinant proteins from Nicotiana benthamiana for structural studies
在非人灵长类动物肝脏中通过可编程基因组整合实现了内源基因替换的治疗水平	Xie, J.	PDF	N/A	Curative levels of endogenous gene replacement achieved in non-human primate liver using programmable genomic integration
探究深度图神经网络在RNA二级结构预测中的效率	Saon, M. S.	PDF	N/A	Exploring the Efficiency of Deep Graph Neural Networks for RNA Secondary Structure Prediction
评估序列和结构相似性指标以预测共享旁系同源功能	Dennler, O.	PDF	N/A	Evaluating Sequence and Structural Similarity Metrics for Predicting Shared Paralog Functions
模式识别受体FLS2的逆向工程揭示了更广泛识别逃避flg22表位的关键设计原则	Zhang, S.	PDF	N/A	Reverse engineering of the pattern recognition receptor FLS2 reveals key design principles of broader recognition spectra against evading flg22 epitopes
无细胞生物传感器的半自动化生产	Brown, D. M.	PDF	N/A	Semi-automated Production of Cell-free Biosensors
杏仁核中适应性价值编码的神经机制	Hinz, J.	PDF	N/A	Neural mechanisms of adaptive value coding in the amygdala
淀粉样β蛋白、α-突触核蛋白和tau蛋白的共病理聚集加剧了神经病理学和神经炎症	Webster, J. M.	PDF	N/A	Amyloid-beta, alpha-synuclein and tau aggregated co-pathologies enhance neuropathology and neuroinflammation
我们能否根据大脑特征预测睡眠健康？一项大规模机器学习研究	Raimondo, F.	PDF	N/A	Can we predict sleep health based on brain features? A large-scale machine learning study
通过首次通过分析追踪神经元树突的形态演变	Kreten, F.	PDF	N/A	Tracking the Morphological Evolution of Neuronal Dendrites by First-Passage Analysis
一个详细的生物物理学模型，描述了皮层感觉处理中区域间相互作用的情况。	Bolanos-Puchet, S.	PDF	N/A	A biophysically-detailed model of inter-areal interactions in cortical sensory processing
X射线衍射揭示了小鼠新皮质中的周期性结构	Murokh, S.	PDF	N/A	X-ray Diffraction Reveals Periodicity in Murine Neocortex
体外活性：羟氯喹与抗生素联合作用对胞内尿路致病性大肠杆菌的效果	Pargny, V.	PDF	N/A	In vitro activity of hydroxychloroquine in combination with antibiotics against intracellular uropathogenic Escherichia coli
表面活性素加速枯草芽孢杆菌菌膜生物膜的形成	Stannius, R. O.	PDF	N/A	Surfactin accelerates Bacillus subtilis pellicle biofilm development
尽管CpG水平升高，HIV-2仍进化出了对ZAP的抗性。	Kmiec, D.	PDF	N/A	HIV-2 evolved ZAP resistance despite increased CpG levels
食品级细菌瑞士乳杆菌VEL12193通过释放膜泡促进自噬。	Bringer, M.-A.	PDF	N/A	The food grade bacterium Lactobacillus helveticus VEL12193 promotes autophagy by releasing membrane vesicles
具有特殊形态的花朵会产生更多的花蜜和花粉吗？	Keasar, T.	PDF	N/A	Do flowers with specialized morphologies produce more nectar and pollen?
悬浮和沉降颗粒相关微生物群在易北河河口展现出不同的生活方式	Tobias-Hünefeldt, S. P.	PDF	N/A	Suspended and sinking particle-associated microbiomesexhibit distinct lifestyles in the Elbe estuary
NAD的二核苷酸结构使其能够在矿物表面上进行特定的还原作用。	Pereira, D. P. H.	PDF	N/A	The dinucleotide structure of NAD enables specific reduction on mineral surfaces
利用新型基因组资源和统计方法结合个体和池化测序数据，对过去和未来斑翅果蝇（Drosophila suzukii）入侵的新见解	Camus, L.	PDF	N/A	New insights into past and future invasion of Drosophila suzukii using novel genomic resources and statistical methods to combine individual and pool sequencing data
利用全基因组关联作图鉴定硬粒冬小麦中的叶锈病抗性位点	Lakkakula, I. P.	PDF	N/A	Identification of leaf rust resistance loci in hard winter wheat using genome-wide association mapping
一种用于菱形蛋白酶RHBDL4酶学特性研究的体外平台	Bhaduri, S. E.	PDF	N/A	An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4
通过计算蛋白质工程改进Split-HaloTag	Wilhelm, J.	PDF	N/A	Improving Split-HaloTag through Computational Protein Engineering
基于噬菌体微流控的PDMS表面定向固定SpyTag噬菌体的研究	Liyanagedera, S. B. W.	PDF	N/A	Directional Immobilisation of SpyTag Bacteriophage on PDMS surfaces for Phage based Microfluidics
利用基础语言模型解读RNA调控	Zhou, H.	PDF	N/A	Deciphering RNA regulation with a foundation language model
高血压中肠道微生物代谢通路紊乱的机制	Wenkai, L.	PDF	N/A	Mechanism of intestinal microbial metabolic flux disorder in hypertension
猪繁殖与呼吸综合征病毒和猪流感A病毒感染对呼吸道淋巴结B细胞和巨噬细胞影响的比较研究。	Hervet, C.	PDF	N/A	Comparative impact of porcine reproductive and respiratory virus and swine influenza A virus infections on respiratory lymph nodes B cells and macrophages.
适应过程中适应性效应分布的动态变化	Morales, D. T.	PDF	N/A	Dynamics of the distribution of fitness effects during adaptation
甲虫-真菌互利共生中共生真菌的基因组多样化	Huang, Y.-T.	PDF	N/A	Genome diversification of symbiotic fungi in beetle-fungus mutualistic symbiosis
塑造微小世界：父系微生物群操控影响后代微生物定植与发育——以性别角色反转的管海马为例	Wagner, K.-S.	PDF	N/A	Shaping tiny worlds: Paternal microbiota manipulation influences offspring microbial colonization and development in a sex role-reversed pipefish
DNA甲基化时钟在区分炎症性衰老与健康衰老方面存在困难，但特征修正能提高一致性并增强对炎症性衰老的检测能力。	Skinner, C. M.	PDF	N/A	DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammaging
UniScore，一种通过多重搜索引擎进行肽段鉴定的统一且通用的评估标准	Tabata, T.	PDF	N/A	UniScore, a unified and universal measure for peptide identification by multiple search engines
DeepAllo：利用蛋白质语言模型（pLM）结合多任务学习进行变构位点预测	Khokhar, M.	PDF	N/A	DeepAllo: Allosteric Site Prediction using Protein Language Model (pLM) with Multitask Learning
RNA测序深度指南，用于研究可变剪接	Tsoy, O.	PDF	N/A	RNA sequencing depth guidelines for the study of alternative splicing
NKX2-2独立调控神经发生和背腹模式形成	Jang, S.	PDF	N/A	Independent control of neurogenesis and dorsoventral patterning by NKX2-2
量化相对海绵性：作为生态系统服务的高分辨率景观水保持模型	Evans, P. M.	PDF	N/A	Quantifying relative sponginess: a high-resolution model of landscape water retention as an ecosystem service
受开发影响的湖泊中冰物候变化产生的连锁后果	Goto, D.	PDF	N/A	Cascading consequences of shifting ice phenology in an exploited lake
# BioRxiv 2024-10-12 Papers

标题	作者	PDF链接	代码仓库	Title
催乳素和DNA损伤会引发抗乳腺癌细胞的免疫反应。	Karayazi Atici, O.	PDF	N/A	Prolactin and DNA damage trigger an anti-breast cancer cellimmune response
启动子近端暂停的进化实现了一层新的转录调控	Chivu, A. G.	PDF	N/A	Evolution of promoter-proximal pausing enabled a new layer of transcription control
北极猛禽的狐步迁徙及动态越冬范围	Pokrovsky, I.	PDF	N/A	Foxtrot migration and dynamic over-wintering range of an arctic raptor
利用光遗传学控制RhoA的GEF揭示了从收缩到突起的信号开关	de Seze, J.	PDF	N/A	Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion
小鼠眶额皮层中信息内在价值的表征	Bussell, J. J.	PDF	N/A	Representations of the intrinsic value of information in mouse orbitofrontal cortex
蚊子发育过程中细菌代谢物的营养性别特异性导致成虫性别比例失衡	Romoli, O.	PDF	N/A	Nutritional sex-specificity on bacterial metabolites during mosquito development leads to adult sex-ratio distortion
经过验证的触摸视频数据库	Smit, S.	PDF	N/A	The validated touch-video database
重新思考休眠：抗生素持久者是具有代谢活性、非生长的细胞	Rahman, K. M. T.	PDF	N/A	Rethinking Dormancy: Antibiotic Persisters are Metabolically Active, Non-Growing Cells
尼古丁通过Hippo-YAP/TAZ和Notch信号通路增强肠干细胞的干性和肿瘤发生能力。	Isotani, R.	PDF	N/A	Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway
有效连接预测感知决策信心、不确定性和速度的分布式神经编码	Asadpour, A.	PDF	N/A	Effective connectivity predicts distributed neural coding of perceptual decision confidence, uncertainty and speed
描述早产儿和足月婴儿在睡眠期间脑活动的时间动态和成熟特征：一项基于EEG微状态的研究。	Adibpour, P.	PDF	N/A	Characterizing the temporal dynamics and maturation of brain activity during sleep: an EEG microstate study in preterm and full-term infants.
SERBP1与PARP1相互作用，并存在于依赖于PARylation的蛋白质复合物中，这些复合物调控剪接、细胞分裂和核糖体生物发生。	Breunig, K.	PDF	N/A	SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis
在运动神经元退化的鼠模型中，脊髓微循环经历了多相的稳态补偿。	Nascimento, F.	PDF	N/A	Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration
与怀疑者相比，超自然信仰者在联合视觉搜索中更快但更不准确地拒绝目标的存在。	Akbari, F.	PDF	N/A	Paranormal believers are quicker but less accurate in rejecting the presence of the target in conjunction visual search compared to skeptics
TRMT1L催化的酪氨酸tRNA上的m22G27对于在氧化应激下实现高效的mRNA翻译和细胞存活是必需的。	Hwang, S.-P.	PDF	N/A	TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress.
全基因组关联分析生长速率在波动和极端温度下的变化	Räsänen, E.	PDF	N/A	Genome-wide association mapping for growth rate at fluctuating and extreme temperatures
有丝分裂期间PI(3,5)P2的不对称性对于不对称液泡遗传至关重要	Huda, M.	PDF	N/A	PI(3,5)P2 asymmetry during mitosis is essential for asymmetric vacuolar inheritance
从蛋白质序列信息设计不同长度的线性和环状肽结合剂	Li, Q.	PDF	N/A	Design of linear and cyclic peptide binders of different lengths from protein sequence information
使用Gibbs采样和edgeR v4进行更快更准确的差异转录表达评估	Baldoni, P. L.	PDF	N/A	Faster and more accurate assessment of differential transcript expression with Gibbs sampling and edgeR v4
Dclk1基因表达的调控网络分析揭示了一个簇细胞-ILC2轴，该轴抑制胰腺肿瘤进展。	Valenti, G.	PDF	N/A	Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression
一罐蠕虫：估算全球蚯蚓物种数量	Decaens, T.	PDF	N/A	A can of worms: estimating the global number of earthworm species
与糖尿病和糖尿病肾病相关的尿液微生物群：系统综述	Graells, T.	PDF	N/A	The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review
核孔蛋白Nup153将剪接机制锚定在核孔上，以实现高效的mRNA加工	De Castro, I.	PDF	N/A	Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing
与满江红（Azolla filiculoides）共培养的水稻植株改变了根系结构和发育阶段的时机	Cannavo', S.	PDF	N/A	Co-cultivating rice plants with Azolla filiculoides modifies root architecture and timing of developmental stages
自上而下的反馈至关重要：类脑连接模式对视听整合的功能影响	Tugsbayar, M.	PDF	N/A	Top-down feedback matters: Functional impact of brainlike connectivity motifs on audiovisual integration
海马长轴功能特化受成年寿命影响	Bowman, C.	PDF	N/A	Adult lifespan effects on functional specialization along the hippocampal long axis
开发具有广泛治疗潜力的临床可行非肌肉肌球蛋白II小分子抑制剂	Radnai, L.	PDF	N/A	Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential
在肝硬化肝脏中进行纯化的梭菌胶原酶间质输注可迅速减少纤维化，且肝毒性最小。	Leaker, B. D.	PDF	N/A	Interstitial infusion of purified collagenase Clostridium histolyticum in the cirrhotic liver causes rapid reduction in fibrosis with minimal liver toxicity
货物适配器身份控制动力蛋白激活的机制和动力学	Gillies, J. P.	PDF	N/A	Cargo adaptor identity controls the mechanism and kinetics of dynein activation
胰岛素抵抗性肥胖中的血浆外泌体加剧三阴性乳腺癌的进展	Llevenes, P.	PDF	N/A	Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer
阿波罗：一种综合性的基于GPU的主机内模拟器，用于模拟病毒进化和感染动力学，涵盖群体、组织和细胞层面。	Perera, D.	PDF	N/A	Apollo: A comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell
口服避孕药对大脑网络的影响：一项重复和扩展研究	Haase, G.	PDF	N/A	Effects of oral contraceptive pills on brain networks: A replication and extension
基准测试用于抗体设计的生成模型	Ucar, T.	PDF	N/A	Benchmarking Generative Models for Antibody Design
食物纳米材料引起的肠道屏障破坏的不良结局路径。	Stanco, D.	PDF	N/A	An Adverse Outcome Pathway for Food Nanomaterial-induced Intestinal Barrier Disruption.
沉浸于自然环境可减弱机械性继发性痛觉过敏的发展：岛叶-丘脑有效连接的作用	Medina, S.	PDF	N/A	Immersion in nature attenuates the development of mechanical secondary hyperalgesia: a role for insulo-thalamic effective connectivity
结直肠癌淋巴结转移相关肠道菌群的鉴定及预测机器学习模型构建	Wu, Y.	PDF	N/A	Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer
循环微小RNA作为慢性肾脏病及其与非透析患者肾脏和心血管结局关联的生物标志物	Ramil - Gomez, O.	PDF	N/A	Circulating microRNAs as biomarkers of chronic kidney disease and its association with renal and cardiovascular outcomes in non-dialysis patients
利用已知的出生情况来解释北冰洋露脊鲸种群估计中的标记延迟	Linden, D. W.	PDF	N/A	Using known births to account for delayed marking in population estimation of North Atlantic right whales
“混合群”的模糊性：现有研究中定义和应用的不一致性	Campbell, J. N.	PDF	N/A	The ambiguity of "hybrid swarm": inconsistent definitions and applications in existing research
人口结构限制了从森林树木的基因组预测和全基因组关联研究中得出的推论。	Slavov, G. T.	PDF	N/A	Population structure limits inferences from genomic prediction and genome-wide association studies in a forest tree
构建用于采集小肠内容物样本的胶囊的逐步方法	Ollagnier, C.	PDF	N/A	Step-by-step methodology for building a capsule to sample small intestine content
去伪存真：结构MRI图像质量评估中的偏差	Provins, c.	PDF	N/A	Defacing biases visual quality assessments of structural MRI
单细胞ATAC-seq数据的多模态整合能够高度准确地描绘出临床相关的肿瘤细胞亚群。	Xiong, K.	PDF	N/A	Multimodal integration of single cell ATAC-seq data enables highly accurate delineation of clinically relevant tumor cell subpopulations
系统挖掘肠道微生物组生物标志物用于炎症性肠病	Yuchen, Z.	PDF	N/A	Systematic Mining of gut microbiota biomarkers for IBD
已发表的兔核糖体rRNA序列中的不一致性：关于序列和位点编号统一性的建议	De, S.	PDF	N/A	Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering
利用肿瘤-免疫动力学综合模型预测慢性髓性白血病患者的无治疗缓解结果	Fassoni, A. C.	PDF	N/A	Predicting treatment-free remission outcomes in Chronic Myeloid Leukemia patients using an integrated model of tumor-immune dynamics
结构和功能证据支持将小鼠的高级视觉区域重新定义为单一的V2区域。	Rowley, D. P.	PDF	N/A	Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2
纤维肌痛患者存在与疾病症状严重程度和抗卫星胶质细胞IgG抗体相关的脂质浓度改变。	Jakobsson, J. E.	PDF	N/A	Fibromyalgia patients have altered lipid concentrations associated with disease symptom severity and anti-satellite glial cell IgG antibodies
焦虑/抑郁个体在认知冲突编码过程中表现出前额叶-颞叶同步性紊乱	Shekara, A.	PDF	N/A	Anxious/depressed individuals exhibit disrupted frontotemporal synchrony during cognitive conflict encoding
皮层阿尔法节律从自然场景背景中插值被遮挡的运动	Yeh, L.-C.	PDF	N/A	Cortical alpha rhythms interpolate occluded motion from natural scene context
AB5枯草杆菌溶素细胞毒素诱导的ISR通过STING激活驱动pDCs中IFN-I的表达	Pierre, P.	PDF	N/A	Induction of the ISR by AB5 subtilase cytotoxin drives IFN-I expression in pDCs via STING activation
HighALPS：在Illumina NextSeq和NovaSeq平台上进行超高通量标记基因扩增子文库制备与测序	Flörl, L.	PDF	N/A	HighALPS: Ultra-High-Throughput Marker-Gene Amplicon Library Preparation and Sequencing on the Illumina NextSeq and NovaSeq Platforms
利用遗传和表观遗传筛选方法，将候选因果自身免疫变异与人类原代T细胞网络相联系。	Ho, C.-H.	PDF	N/A	Linking candidate causal autoimmune variants to T cell networks using genetic and epigenetic screens in primary human T cells.
禾草等长穗（Alopecurus aequalis）的染色体规模基因组组装与从头注释。	Wright, J.	PDF	N/A	Chromosome-scale genome assembly and de novo annotation of Alopecurus aequalis.
三叶草复合体中重复的靶心图案减少的遗传基础	Yeo, M. T. S.	PDF	N/A	The genetic basis of replicated bullseye pattern reduction across the Trionum Complex
性别特异性：体力活动强度和剂量对BOLD-fMRI脑血管反应性和脑脉动性的影响	Potvin-Jutras, Z.	PDF	N/A	Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility
高分辨率的黑色素皮质素-4受体深度突变扫描为药物发现提供了目标特征	Howard, C. J.	PDF	N/A	High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
利用基于成像的分子记录技术重构单细胞信号传导历史	Hao, K.	PDF	N/A	Reconstructing signaling history of single cells with imaging-based molecular recording
生物分子自适应控制器设计以恢复持续的周期性行为	Britto Bisso, F.	PDF	N/A	Design of a biomolecular adaptive controller to restore sustained periodic behavior
基础成纤维细胞生长因子有助于保护面部神经细胞在冷冻诱导的瘫痪模型中	Iwata, S.	PDF	N/A	Basic fibroblast growth factor helps protect facial nerve cells in a freeze-induced paralysis model
猕猴和人胎盘类器官的比较分析突显了胎盘形成中的进化差异	Caldwell, A.	PDF	N/A	Comparative analysis of rhesus macaque and human placental organoids highlights evolutionary differences in placentation
通过锌指抑制因子驱动的表观遗传沉默，增强CAR-T细胞和TILs中免疫检查点和TGFBR2的抗肿瘤活性	David, M.	PDF	N/A	Enhanced anti-tumor activity by Zinc Finger Repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs
TGFβ1-TNFα调控的中性粒细胞趋化因子分泌与乳腺癌细胞的上皮-间质转化无关	Sengupta, S.	PDF	N/A	TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells
绘制乳腺癌的时间景观：利用表观遗传熵	Monyak, D. L.	PDF	N/A	Mapping the Temporal Landscape of Breast Cancer Using Epigenetic Entropy
精选癌症细胞图谱：全面解析肿瘤在单细胞分辨率下的特征	Tyler, M.	PDF	N/A	The Curated Cancer Cell Atlas: comprehensive characterisation of tumours at single-cell resolution
干龟国家公园石珊瑚种类的代谢组学特征显示出种间和种内变异。	Deutsch, J. M.	PDF	N/A	Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation
饲喂水葫芦（Eichhornia crassipes）饲料，无论是否添加商业浓缩物，对热带山羊和绵羊的动物技术性能及盈利能力的影响	Fanta, Y. U.	PDF	N/A	Effects of feeding water hyacinth (Eichhornia crassipes) fodder with or without commercial concentrate on zoo-technical performance and profitability in tropical goats and sheep
通过体外功能细胞集合体绘制突触集合体	Zaccaria, C.	PDF	N/A	Mapping Synaptic Ensembles Through In Vitro Functional Cell Assemblies
噪声中神经语音追踪的SNR、语音可懂度和注意力努力的不同作用	He, X.	PDF	N/A	Distinct roles of SNR, speech Intelligibility, and attentional effort on neural speech tracking in noise
多丝氨酸肽具有毒性，并会加剧小鼠中的tau病理变化。	Van Alstyne, M.	PDF	N/A	Polyserine peptides are toxic and exacerbate tau pathology in mice
三维定量微弹性成像揭示了小鼠卵巢在衰老过程中卵泡和黄体的空间弹性模式的变化。	Jaeschke, A.	PDF	N/A	Three-dimensional quantitative micro-elastography reveals alterations in spatial elasticity patterns of follicles and corpora lutea in murine ovaries during ageing
一种新烟碱类杀虫剂导致熊蜂组织特异性基因表达变化	Witwicka, A.	PDF	N/A	A neonicotinoid pesticide causes tissue-specific gene expression changes in bumble bees
神秘浇水壶贝的基因组揭示了活体吸盘锚的适应性	Sigwart, J.	PDF	N/A	Genome of the enigmatic watering-pot shell reveals adaptations of a living suction anchor
ReAct项目：分析来自23个不同实验室的数据，以表征在两组活动水平命题下的DNA恢复情况	Gill, P.	PDF	N/A	The ReAct project: Analysis of data from 23 differentlaboratories to characterise DNA recovery given twosets of activity level propositions
一种保守转录因子结合位点图谱揭示了开花植物的细胞类型解析基因调控景观	Baumgart, L. A.	PDF	N/A	An atlas of conserved transcription factor binding sites reveals the cell type-resolved gene regulatory landscape of flowering plants
公开的RNA-seq数据并不能全面代表全球人类的多样性。	Gallego Romero, I.	PDF	N/A	Public RNA-seq data are not representative of global human diversity
耐热的阿拉伯鳉鱼（Aphanius dispar）作为一种新型感染模型，用于研究人类真菌病原体	Minhas, R.	PDF	N/A	The thermotolerant Arabian killifish, Aphanius dispar, as a novel infection model for human fungal pathogens
蜜蜂飞行中的群体协调依赖于成对相互作用、反馈规则变化以及深思熟虑的决策。	Faruque, I.	PDF	N/A	Pairwise interactions, feedback rule changes, and deliberative decisions underlie honeybee inflight group coordination
小鼠皮质卒中后的比例恢复	Kalantari, A.	PDF	N/A	Proportional recovery in mice with cortical stroke
繁殖经历促使雄性加州田鼠（Peromyscus californicus）在行为和生理上发生改变。	Colt, M. E.	PDF	N/A	Reproductive experience drives changes in behavior and physiology in male California mice (Peromyscus californicus)
利用深度学习设计新型PHA合成酶	Tenkanen, T.	PDF	N/A	New-to-nature PHA synthase design using deep learning
非侵入式脑机接口控制与人工智能副驾驶	Lee, J. Y.	PDF	N/A	Non-invasive brain-machine interface control with artificial intelligence copilots
一款全面的应用程序，用于解读和可视化KEGG通路和基因本体论的功能分析	Mena, A. R.	PDF	N/A	A Comprehensive App to Interpret and Visualize the Functional Analysis of KEGG Pathways and Gene Ontologies
DigestR是一款开源软件工具，用于可视化由天然蛋白质分解产生的LC-MS蛋白质组学数据。	de Lamache, D. D.	PDF	N/A	DigestR an open-source software tool for visualizing LC-MS proteomics data resulting from natural protein catabolism
vScreenML v2.0：改进的基于结构的虚拟筛选中减少假阳性的人工智能分类技术	Andrianov, G. V.	PDF	N/A	vScreenML v2.0: Improved Machine Learning Classification for Reducing False Positives in Structure-Based Virtual Screening
PROPERMAB：一种利用机器学习进行抗体可开发性计算机预测的综合框架	Li, B.	PDF	N/A	PROPERMAB: an integrative framework for in silico prediction of antibody developability using machine learning
物种丰富度估算的综合评述与评价	Schmitz, J. E.	PDF	N/A	A Comprehensive Review and Evaluation of Species Richness Estimation
聚合物模型结合超分辨率成像和表观基因组测序，阐明表观遗传反应在塑造四维染色质组织中的作用	Vinayak, V.	PDF	N/A	Polymer Model Integrates Super-Resolution Imaging and Epigenomic Sequencing to Elucidate the Role of Epigenetic Reactions in Shaping 4D Chromatin Organization
鲁索利替尼通过泛素-蛋白酶体系统清除CRYAB p.Arg120Gly聚集物	Alizoti, E.	PDF	N/A	Ruxolitinib clears CRYAB p.Arg120Gly aggregates through the ubiquitin-proteasome system
代谢精细调节和心脏细胞因子分泌是果蝇对高脂肪和高糖饮食的适应性反应。	Khamvongsa-Charbonnier, L.	PDF	N/A	Metabolism fine tuning and cardiokines secretion represent adaptative responses of the heart to High Fat and High Sugar Diets in flies
一种新的肌肉收缩离体模型，用于测量肌肉内分泌和旁分泌信号传导	DABADIE, C.	PDF	N/A	A novel ex vivo model of muscle contraction to measure muscle endocrine and paracrine signalling
通过神经元受体进行细菌感应，启动肠道线粒体监测以适应宿主	Liu, H.	PDF	N/A	Bacterial sensing via Neuronal Receptor Initiates Gut Mitochondrial Surveillance for Host Adaptation
经颅超声皮质电路刺激的微观解构	Lemaire, T.	PDF	N/A	Microscopic deconstruction of cortical circuit stimulation by transcranial ultrasound
在感染SIV的恒河猴中，大麻素使基底神经节的miRNA m6A甲基化谱向抗炎表型转变。	Okeoma, C. M.	PDF	N/A	Cannabinoids shift the basal ganglia miRNA m6A methylation profile towards an anti-inflammatory phenotype in SIV-infected Rhesus macaques
纹状体伏隔核通路通过一个厌恶性的Esr1+下丘脑-缰核回路驱动强迫性寻求行为。	Contesse, T.	PDF	N/A	A striosomal accumbens pathway drives compulsive seeking behaviors through an aversive Esr1+ hypothalamic-habenula circuit.
小血管脑病遗传决定因子TRIM47通过NRF2抗氧化系统调控脑稳态	Duplaa, C.	PDF	N/A	Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system
结合计算流体动力学建模和几何形态计量学方法，量化从光片荧光显微镜成像重建的胚胎鸡心脏解剖结构的血流动力学和解剖特征	Giesbrecht, K.	PDF	N/A	A Combined Computational Fluid Dynamics Modeling and Geometric Morphometrics Methods Approach to Quantifying Hemodynamic and Anatomical Features of Embryonic Chick Heart Anatomies Reconstructed from Light Sheet Fluorescence Microscopy Imaging
从木本被子植物的木质部特异性肽前体中衍生出的进化保守的树液肽	Chen, C.-H.	PDF	N/A	Evolutionary conserved sap peptides derived from xylem-specific peptide precursors in woody angiosperms
单细胞整合揭示了炎症性肠病中的化生现象	Oliver, A. J.	PDF	N/A	Single Cell Integration Characterises Metaplasia in Inflammatory Intestinal Diseases
动态屏障调节着粘连蛋白定位和固定占用率下的基因组折叠	Rahmaninejad, H.	PDF	N/A	Dynamic barriers modulate cohesin positioning and genome folding at fixed occupancy
利用高斯过程估计重建的多带成像加速多壳扩散磁共振成像	Ye, X.	PDF	N/A	Accelerated multi-shell diffusion MRI with Gaussian process estimated reconstruction of multi-band imaging
通过磁遗传学工具调控人类T淋巴细胞	Helalat, S. H.	PDF	N/A	Regulating Human T Lymphocytes Through Magnetogenetic Tools
模拟揭示了着陆运动学变量如何影响最高短跑速度：对教练的启示	Haralabidis, N.	PDF	N/A	Simulations reveal how touchdown kinematic variables affect top sprinting speed: implications for coaching
通过多模态学习实现大规模蛋白质数据的递归清洗	Jiang, Z.	PDF	N/A	Recursive Cleaning for Large-scale Protein Data via Multimodal Learning
利用加权蛋白质-蛋白质相互作用网络进行人类必需基因的深度预测	Mehrpou, S.	PDF	N/A	Deep Prediction of Human Essential Genes using Weighted Protein-Protein Interaction Networks
一个基于化合物生物活性谱的扩散模型，用于预测高内涵图像	Cook, S.	PDF	N/A	A diffusion model conditioned on compound bioactivity profiles for predicting high-content images
对来自全球的象草（Cenchrus purpureus）进行全基因组重测序，以探索全球种群结构及控制产量和饲料质量性状的QTL	Teshome, A.	PDF	N/A	Whole genome resequencing of a global collection of Napier grass (Cenchrus purpureus) to explore global population structure and QTL governing yield and feed quality traits
SAMPL-seq揭示了人类肠道微生物组中的微米级空间枢纽	Richardson, M.	PDF	N/A	SAMPL-seq reveals micron-scale spatial hubs in the human gut microbiome
关于“快速封盖移除”的科学笔记——一种评估蜜蜂（Apis mellifera）幼虫感染Tropilaelaps mercedesae的方法	Uzunov, A.	PDF	N/A	A scientific note on "Rapid brood decapping" - a method for assessment of honey bee (Apis mellifera) brood infestation with Tropilaelaps mercedesae
解码难以理解的声音：在低信噪比条件下的神经语音追踪	He, X.	PDF	N/A	Decoding the Unintelligible: Neural Speech Tracking in Low Signal-to-Noise Ratios
深度聚焦：一种通过鼻腔途径优化奖赏环路节点深部脑刺激的方法	Guo, Y.	PDF	N/A	DeepFocus: A Transnasal Approach for Optimized Deep Brain Stimulation of Reward Circuit Nodes
亚单位mRNA鸡尾酒疫苗的选择、设计和免疫原性研究：针对特定免疫反应谱的ASFV抗原	Yuan, F.	PDF	N/A	Selection, Design and Immunogenicity Studies of ASFV Antigens for Subunit mRNA Cocktail Vaccines with Specific Immune Response Profiles
鼻内注射血凝素蛋白增强剂可诱导强效的黏膜免疫，并提供针对甲型流感病毒攻击的交叉保护。	Moriyama, M.	PDF	N/A	Intranasal hemagglutinin protein boosters induce robust mucosal immunity and cross-protection against influenza A viral challenge
从具有一个时间戳和多个观测值的生态时间序列中进行因果发现	Bystrova, D.	PDF	N/A	Causal discovery from ecological time-series with one timestamp and multiple observations
在系统发育和生态学上界定的物种库影响了对依赖年龄的灭绝的推断。	Goncalves-Neto, S.	PDF	N/A	Phylogenetically and ecologically delimited species pool affect the inference of age-dependent extinction
一种新发现的苋属植物（Amaranthus palmeri）染色体外环状DNA中的基因组重排，使其同时对草甘膦和草铵膦两种除草剂产生抗性。	Carvalho-Moore, P.	PDF	N/A	A Novel Genomic Rearrangement in the Amaranthus palmeri Extrachromosomal Circular DNA Provides Dual Herbicide Resistance to Glyphosate and Glufosinate
PRC2促进了幼苗萌发过程中从异养到自养的转变	Samo, N.	PDF	N/A	PRC2 facilitates the transition from heterotrophy to photoautotrophy during seedling emergence
早期经历对野生果蝠的觅食行为影响更大，超过了它们原本的行为倾向。	Rachum, A.	PDF	N/A	Early experience affects foraging behavior of wild fruit-bats more than their original behavioral predispositions
海马体与皮层在社交记忆巩固中的相互作用	Park, G.	PDF	N/A	Hippocampal-cortical interactions in the consolidation of social memory
黑猩猩展示中的情境依赖性节奏性	van der Vleuten, B.	PDF	N/A	Context-dependent Rhythmicity in Chimpanzee Displays
利用迁移学习预测蛋白质-小分子相互作用	Wang, J.	PDF	N/A	Leveraging Transfer Learning for Predicting Protein-Small Molecule Interactions
奖励驱动的小脑爬行纤维活动影响神经和行为学习	Jin, S.	PDF	N/A	Reward-driven cerebellar climbing fiber activity influences both neural and behavioral learning
一种针对恒河猴的新型表观遗传时钟揭示了早期生活逆境与表观遗传年龄加速之间的关联	Bronk, G.	PDF	N/A	A novel epigenetic clock for rhesus macaques unveils an association between early life adversity and epigenetic age acceleration
饮酒性依赖地改变小鼠皮层IL-1β突触信号传导和认知行为	Liss, A.	PDF	N/A	Ethanol drinking sex-dependently alters cortical IL-1β synaptic signaling and cognitive behavior in mice
在顶叶和前额叶皮层中，逐步分离运动和认知序列	Doyle, H.	PDF	N/A	Ramping dissociates motor and cognitive sequences in the parietal and prefrontal cortices
刚地弓形虫入侵宿主细胞时，穿孔宿主细胞质膜需要棒状体胞吐作用。	Male, F.	PDF	N/A	Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis
用于自动收集培养细胞时间分辨代谢组学数据的LC-MS系统	Chan, C. C. Y.	PDF	N/A	LC-MS system for automatically collecting time-resolved metabolomics data of cultured cells
退耕还草对土壤原核生物、真菌和原生生物的复杂响应	Tosi, M.	PDF	N/A	Complex responses of soil prokaryotes, fungi and protists to prairie restoration on retired agricultural lands
因果中介中的高维混淆：双重机器学习与正则化偏相关网络的比较研究	Chen, M.	PDF	N/A	High-dimensional confounding in causal mediation: a comparison study of double machine learning and regularized partial correlation network
整合接合元件对SOS反应和同源重组的调控	Garcia Heredia, A.	PDF	N/A	Regulation of the SOS response and homologous recombination by an integrative and conjugative element
染色质环境对DOT1L在雄性生殖细胞基因表达中的影响	Coulee, M.	PDF	N/A	Chromatin Environment-Dependent Effects of DOT1L on Gene Expression in Male Germ Cells
胎儿肝样类器官再现了血液-肝脏微环境发育及人类多能干细胞的多能造血过程	Rezvani, M.	PDF	N/A	Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells
丝状伪足样结构对类固醇释放至关重要	Simon, E.	PDF	N/A	Filopodia-like Structures are Essential for Steroid Release
在人类早期多能性和细胞谱系中，WNT介导的TCF/LEF转录因子基因表达与啮齿动物模型有所不同。	Ross, C.	PDF	N/A	WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm
非洲爪蟾的呼吸系统揭示了四足动物在生长、再生和愈合方面的共同机制	Perry, S. K.	PDF	N/A	The Xenopus respiratory system reveals common tetrapod mechanisms for growth, regeneration and healing
雄性是默认性别：角粪甲虫性别决定级联的功能意义	Mitchell, L. C.	PDF	N/A	Male is the default sex: functional significance of the sex determination cascade in horned dung beetles
实验性短期热浪对野生传粉者在幼虫发育期间的体重增加和存活率产生负面影响。	Woegler, L.	PDF	N/A	Experimental short-term heatwaves negatively impact body weight gain and survival during larval development in a wild pollinator
脊髓祖细胞中CDKN1c/p57kip2低表达促使细胞从增殖性分裂模式向神经发生性分裂模式转变	Mida, B.	PDF	N/A	A low CDKN1c/p57kip2 expression in spinal progenitors drives the transition from proliferative to neurogenic modes of division
一种调控蟑螂卵子发生和胚胎发育的piRNA	Gonzalvo, J.	PDF	N/A	A piRNA regulating oogenesis and embryo development in cockroaches
硫蝶翅膀性二态性和鳞片细胞特化的单核转录组学研究	Loh, L. S.	PDF	N/A	Single-nucleus transcriptomics of wing sexual dimorphism and scale cell specialization in sulphur butterflies
一种油菜素内酯受体激酶对于同型孢子蕨类植物Ceratopteris richardii的性别决定是必需的。	Burow, K. M.	PDF	N/A	A brassinosteroid receptor kinase is required for sex determination in the homosporous fern Ceratopteris richardii
Orthrus：迈向进化和功能性的RNA基础模型	Fradkin, P.	PDF	N/A	Orthrus: Towards Evolutionary and Functional RNA Foundation Models
浊度感官方法：来源与水平如何塑造水生光环境与鱼类视觉生态	Garcia, A.	PDF	N/A	A sensory approach to turbidity: How sources and levels shape aquatic light environments and fish visual ecology
R2-D2：模仿《星球大战》机器人揭示了鹦鹉和椋鸟的异种声音模仿能力	Dam, N. C. P.	PDF	N/A	Artoo-Detoo: What imitating a Star Wars droid reveals on allospecific vocal imitation in parrots and starlings
揭示社会认知中的潜在动态：多智能体逆强化学习	Chen, Y.	PDF	N/A	Unveiling the latent dynamics in social cognition with multi-agent inverse reinforcement learning
强迫性应对策略与适应性应对策略的肾上腺素能和巴甫洛夫基础	Chernoff, C. S.	PDF	N/A	Noradrenergic and Pavlovian underpinnings of compulsive versus adaptive coping strategies
和弦的协和性：三和弦中每个音的半音变化对其感知协和性的影响	Varkevisser, J.	PDF	N/A	The consonance of chords: The effect of subsemitone changes to each of the notes in a trichord on its perceived consonance
X-Tracker：非洲爪蟾蝌蚪视觉回避行为的自动化分析	McKeown, C. R.	PDF	N/A	X-Tracker: Automated Analysis of Xenopus Tadpole Visual Avoidance Behavior
解开苯基琥珀酸合酶的对映选择性机制：通过多尺度建模和动力学研究厌氧烃降解的见解	Szaleniec, M.	PDF	N/A	Unravelling the Enantioselective Mechanism of Benzylsuccinate Synthase: Insights into Anaerobic Hydrocarbon Degradation Through Multiscale Modelling and Kinetics
一种能够合成自身及其互补链的聚合酶核酶	Gianni, E.	PDF	N/A	A polymerase ribozyme that can synthesize both itself and its complementary strand
蛋白质组装的以键为中心的模块化设计	Wang, S.	PDF	N/A	Bond-centric modular design of protein assemblies
利用-配对靶向RF扩散改进蛋白质结合剂设计	Sappington, I.	PDF	N/A	Improved protein binder design using -pairing targeted RFdiffusion
定义K1样杀伤毒素的α域	Coss, S. A.	PDF	N/A	Defining the alpha domains of K1-like killer toxins
使用贝叶斯狄利克雷过程模型建模微生物组与宿主表型之间的关联	Awany, D.	PDF	N/A	Modelling Microbiome Association with Host Phenotypes Using a Bayesian Dirichlet Process Model
多巴胺D2受体对分离斑马鱼鳃中氧感受器的抑制作用	Reed, M.	PDF	N/A	Oxygen chemoreceptor inhibition by dopamine D2 receptors in isolated zebrafish gills
通过超高效液相色谱-四极杆飞行时间质谱（UPLC-QTOF-MS）和气相色谱-串联质谱（GC-MS/MS）分析以及体外生物活性评估，对印度山蚂蝗（Desmodium gangeticum DC.）进行化学特征分析。	Jagtap, M. A.	PDF	N/A	Chemo-Profiling by UPLC-QTOF-MS, GC-MS/MS analysis and In Vitro Bioactivity Assessment of Desmodium gangeticum DC.
味觉处理的演变改变了饮食偏好	Bertolini, E.	PDF	N/A	Evolution of taste processing shifts dietary preference
语义抑制与再激活：从语义理解到审美欣赏的超越——来自审美阅读的fNIRS证据	Liu, H.	PDF	N/A	Semantic Inhibition and Reactivation for Transcending from Semantic Understanding to Aesthetic Appreciation: fNIRS Evidence from Aesthetic Reading
单分子表征：Aducanumab、Lecanemab、Gantenerumab 和 Donanemab 对可溶性β淀粉样蛋白聚集体的结合特性	Fertan, E.	PDF	N/A	Single-molecule characterisation of soluble beta-amyloid aggregate binding by Aducanumab, Lecanemab, Gantenerumab, and Donanemab
认知需求和听觉噪音对姿势动态的影响	Carey, S.	PDF	N/A	Influence of Cognitive Demand and Auditory Noise on Postural Dynamics
HDAC抑制剂在体外重现了与人类疾病相关的小胶质细胞特征	Haage, V. C.	PDF	N/A	HDAC Inhibitors recapitulate Human Disease-Associated Microglia Signatures in vitro
自闭症谱系障碍啮齿动物模型中依赖于活动的整体内吞作用的趋同性抑制。	Bonnycastle, K.	PDF	N/A	Convergent depression of activity-dependent bulk endocytosis in rodent models of autism spectrum disorders.
在人脑皮层视觉刺激过程中同时定量氧气和葡萄糖消耗	Epp, S. M.	PDF	N/A	Simultaneous quantification of oxygen and glucose consumption during visual stimulation in the human cortex
甘氨酰-tRNA的隔离是一种统一机制，它解释了与GARS1相关的外周神经病变。	Mora, N.	PDF	N/A	Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy
一种图神经网络方法研究神经发育过程中大脑临界状态	Cabral-Carvalho, R. M.	PDF	N/A	A Graph Neural Network Approach to Investigate Brain Critical States Over Neurodevelopment
在阿尔茨海默病敲入模型中早期破坏内嗅皮层的多巴胺	Nakagawa, T.	PDF	N/A	Early disruption of entorhinal dopamine in a knock-in model of Alzheimer's disease
SSRIs对中缝背核5-羟色胺神经元空间转录组的影响	Henningson, C.	PDF	N/A	Effects of SSRIs on the spatial transcriptome of dorsal raphe serotonin neurons
视觉刺激的接近性降低了眼跳后的α波侧化	Turner, C.	PDF	N/A	Proximity to Visual Stimuli Reduces Post-Saccadic Alpha Lateralisation
TENM4是触觉和痛觉传导的重要转导成分。	Khallaf, M.	PDF	N/A	TENM4 is an essential transduction component for touch and pain
亚毫米级扩散磁共振成像：采用平面内分段三维多片采集与去噪器正则化重建	Li, Z.	PDF	N/A	Submillimeter diffusion MRI using an in-plane segmented 3D multi-slab acquisition and denoiser-regularized reconstruction
在几何网络模型中，减少节点的空间扩散能够改善与计算能力提升相关的拓扑结构。	Christiansen, N.	PDF	N/A	Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities
蜜蜂睡眠的神经相关性	Moguilner, S.	PDF	N/A	Neuronal correlates of sleep in honey bees
期望生成及其对后续疼痛和视觉感知的影响	Botvinik-Nezer, R.	PDF	N/A	Expectation generation and its effect on subsequent pain and visual perception
tDCS颅神经协同刺激：揭示大鼠三叉神经直流电刺激涉及的脑干通路	Majdi, A.	PDF	N/A	tDCS Cranial Nerve Co-Stimulation: Unveiling Brainstem Pathways Involved in Trigeminal Nerve Direct Current Stimulation in Rats
图雷特综合症中的丘脑-额叶连接模式：结合颅内深部脑刺激和脑电图记录的见解	Wehmeyer, L.	PDF	N/A	Thalamo-frontal connectivity patterns in Tourette Syndrome: Insights from combined intracranial DBS and EEG recordings
淀粉样前体蛋白（Amyloid Beta Precursor Protein）有助于短命的青绿色鳉鱼（Nothobranchius furzeri）的脑老化和学习能力下降。	de Bakker, D. E. M.	PDF	N/A	Amyloid Beta Precursor Protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri)
一种用于正电子发射断层扫描成像的μ阿片受体小分子拮抗剂放射性示踪剂。	Plakas, K.	PDF	N/A	A Small-molecule Antagonist Radiotracer for Positron Emission Tomography Imaging of the Mu Opioid Receptor.
纹状体侧向抑制调节左旋多巴诱导的运动障碍小鼠模型中的动作选择	Twedell, E. L.	PDF	N/A	Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia
hMT+活动预测空间注意对周围抑制的影响	Kiniklioglu, M.	PDF	N/A	hMT+ Activity Predicts the Effect Of Spatial Attention On Surround Suppression
大鼠岛叶皮层对刺激引导行为的贡献	Tensaouti, Y.	PDF	N/A	Contribution of rat insular cortex to stimulus-guided action
在稳定注视和主动视觉过程中刺激特征的表征	Moran, C.	PDF	N/A	The representation of stimulus features during stable fixation and active vision
脂质组学分析揭示了散发性帕金森病与GBA突变携带者中共享及独特的病理特征：对疾病机制的启示	Munoz, S. S.	PDF	N/A	Lipidomic Profiling Reveals Shared and Distinct Pathological Signatures in Sporadic Parkinson's Disease and GBA Mutation Carriers: Implications for Disease Mechanisms
物体接触前后皮层抓握相关活动的变化	Yan, Y.	PDF	N/A	Changes in cortical grasp-related activity before and after object contact
成长中的小脑：从婴儿到学龄的脑功能发育	Lyu, W.	PDF	N/A	The Growing Little Brain: Cerebellar Functional Development from Cradle to School
食物摄入会增强海马体中的锋电波-波纹复合体。	Kaya, E.	PDF	N/A	Food intake enhances hippocampal sharp wave-ripples
通过IP1检测，小鼠大脑中5-HT2A受体激活的快照	de la Fuente Revenga, M.	PDF	N/A	Snapshot of 5-HT2A receptor activation in the mouse brain via IP1 detection
Gasdermin D 被激活但在 SOD1G93A 模型中不驱动神经退行性变：针对细胞焦亡的潜在意义	Gunner, G.	PDF	N/A	Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis
光线通过交感神经系统调节葡萄糖和脂质稳态	Chen, X.	PDF	N/A	Light modulates glucose and lipid homeostasis via the sympathetic nervous system
脑部预靶向PET - 利用单克隆抗体成像中枢神经系统靶点的新视野	Gustavsson, T.	PDF	N/A	Brain Pretargeted PET - New Horizons to Image CNS Targets with Monoclonal Antibodies
基于荧光寿命的FRET生物传感器用于监测活细胞中TDP-43的N端结构域相互作用：一种用于ALS和FTD药物发现的新资源	Nathan Kochen, N.	PDF	N/A	Fluorescence lifetime-based FRET biosensors for monitoring N-terminal domain interactions of TDP-43 in living cells: A novel resource for ALS and FTD drug discovery
老年小鼠的平衡表现依赖于单极刷状细胞	Kizeev, G.	PDF	N/A	Balance performance in aged mice is dependent on unipolar brush cells
通过抑制性突触可塑性实现递归神经回路中的结构化稳定	Festa, D.	PDF	N/A	Structured stabilization in recurrent neural circuits through inhibitory synaptic plasticity
基底外侧杏仁核中II组代谢型谷氨酸受体的激活抑制了由辨别性刺激引发的奖赏寻求行为	LeCocq, M. R.	PDF	N/A	Activation of Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Reward Seeking Triggered by Discriminative Stimuli
持续性钠电流在Scn8a功能获得性小鼠中将癫痫与扩散性去极化联系起来	Aiba, I.	PDF	N/A	Persistent Na+ current couples seizure with Spreading depolarization in Scn8a gain-of-function mice
溶栓通过依赖于血管内皮生长因子B（VEGF-B）对脂肪分解的影响，加剧了缺血性卒中后的脑血管损伤。	Nilsson, I.	PDF	N/A	Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis
超越CTCT：特发性震颤患者接受磁共振引导聚焦超声（VIM-MRgFUS）治疗后的远期结构变化	Krauss, J.	PDF	N/A	Beyond the CTCT: Remote Structural Changes After VIM-MRgFUS in Essential Tremor
使用循环机制模型快速、可解释、数据驱动的神经动力学模型	Burghi, T. B.	PDF	N/A	Rapid, interpretable, data-driven models of neural dynamics using Recurrent Mechanistic Models
多站点研究中结构脑网络的协调	Shen, R. S.	PDF	N/A	Harmonization of Structural Brain Networks for Multi-site Studies
使用隐马尔可夫模型表征先天盲人的动态功能连接	Pedersini, C. A.	PDF	N/A	Characterizing dynamic functional connectivity in congenitally blind people using Hidden Markov Models
特定区域的扩散去极化驱动异常的癫痫后行为	Mitlasoczki, B.	PDF	N/A	Region-specific spreading depolarization drives aberrant post-ictal behavior
睡眠结构与阿尔茨海默病病理的区域性关联	Buchal, A.	PDF	N/A	Regional associations of sleep architecture and Alzheimer's disease pathology
前脑岛中的温度感知预测和预测误差	Toussaint, B.	PDF	N/A	Thermoceptive predictions and prediction errors in the anterior insula
通过遗传手段降低翻译抑制因子FMRP和4E-BP2的水平，可以保护阿尔茨海默病小鼠模型的记忆功能。	Campos Ribeiro, F.	PDF	N/A	Genetic reduction of the translational repressors FMRP and 4E-BP2 preserves memory in mouse models of Alzheimer's disease
星形胶质细胞Kir4.1通道在脊髓损伤后痉挛中的功能贡献	Barbay, T.	PDF	N/A	Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injury
多组学特征分析揭示，在Sp4突变小鼠（一种精神分裂症和双相情感障碍的遗传模型）中，全脑突触广泛紊乱，神经元和胶质细胞呈现区域特异性和年龄特异性的变化。	Kwon, M. J.	PDF	N/A	Muti-omics characterization reveals brain-wide disruption of synapses and region- and age-specific changes in neurons and glia in Sp4 mutant mice, a genetic model of schizophrenia and bipolar disorder
RiboTag RNA测序揭示脑缺血后星形胶质细胞终足中HSP70的局部翻译	Shim, B.	PDF	N/A	RiboTag RNA Sequencing Identifies Local Translation of HSP70 In Astrocyte Endfeet After Cerebral Ischemia
嗅觉转导电流的放大实现了稀疏刺激编码	Belonio, K. C.	PDF	N/A	Amplification of olfactory transduction currents implements sparse stimulus encoding
奥罗波切正布尼亚病毒神经感染的特征	Connors, K. A.	PDF	N/A	Characterization of neural infection by Oropouche orthobunyavirus
微流控装置中盘基网柄菌细胞在剪切应力依赖性粘附与运动行为的定量测量	Fakhari, S.	PDF	N/A	Quantitative measurements of shear stress-dependent adhesion and motion of Dictyostelium discoideum cells in a microfluidic device
通过单细胞多组学分析解读小鼠胚胎皮肤中的基因调控程序	Deng, Q.	PDF	N/A	Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis
STAT3信号传导增强了植入后小鼠发育期间的组织扩张	Nichols, J.	PDF	N/A	STAT3 signalling enhances tissue expansion during postimplantation mouse development
基于CRISPR/Cas9的鸟类胚胎体内报告基因敲入	Petit-Vargas, A.	PDF	N/A	CRISPR/Cas9-based somatic knock-in of reporters in the avian embryo in ovo
细胞信号突起在脊髓神经发生中实现动态远距离接触	Hawley, J.	PDF	N/A	Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis
CellMet: 从细胞和组织中提取三维形态学指标	Theis, S.	PDF	N/A	CellMet: Extracting 3D shape metrics from cells and tissues
鉴定果蝇变态过程的特化脂质屏障	Lampe, L.	PDF	N/A	Identification of a specialized lipid barrier for Drosophila metamorphosis
克服倍性障碍：三倍体桥梁在碎米荠属植物遗传渗入中的作用	Bartolic, P.	PDF	N/A	Overcoming ploidy barriers: the role of triploid bridges in the genetic introgression of Cardamine amara
昆虫的基因组预测：以黄蜂Nasonia vitripennis翅膀形态特征为例的研究	Xia, S.	PDF	N/A	Genomic prediction in insects: a case study on wing morphology traits in the jewel wasp Nasonia vitripennis
在模糊地形中自由觅食的猕猴重视信息	Shahidi, N.	PDF	N/A	Freely foraging macaques value information in ambiguous terrains
在啮齿动物径向迷宫任务中，前额叶对回顾性空间工作记忆的表征	Taliaferro, J. P.	PDF	N/A	Prefrontal representations of retrospective spatial working memory in a rodent radial maze task
当对手不在时：雄性蓝鳍鳉对雌性的攻击行为	Karatgi, R.	PDF	N/A	When Rivals Are Absent: Male Aggression Towards Females in Bluefin Killifish
全流程三维电化学微胶囊封装类器官自动化高通量筛选平台加速罕见病药物研发	Xu, Z.	PDF	N/A	Whole-Process 3D ECM-Encapsulated Organoid-Based Automated High-Throughput Screening Platform Accelerates Drug Discovery for Rare Diseases
复杂多途径反应动力学分析：胰岛素二聚体解离	Jeong, K.	PDF	N/A	Analysis of the dynamics of a complex, multipathway reaction: Insulin dimer dissociation
脊髓脑脊液接触神经元是沿小鼠脊髓分布的一种保守的感觉神经元群体。	CROZAT, E.	PDF	N/A	Spinal cerebrospinal fluid contacting neurons are a conserved sensory neuronal population along the mouse spinal cord
人类内侧颞叶中记忆形成与回忆之间时间顺序的神经编码得以保留	Khazali, M. F.	PDF	N/A	A preserved neural code for temporal order between memory formation and recall in the human medial temporal lobe
Dnajc3（HSP40）调节小鼠视神经的轴突再生	Wang, J.	PDF	N/A	Dnajc3 (HSP40) Modulates Axon Regeneration in the Mouse Optic Nerve
改进的螺旋神经节神经元的光遗传学修饰，用于未来的光学耳蜗植入	Thirumalai, A.	PDF	N/A	Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants
估计平均值：时间间隔摘要表征的行为和神经相关性	Otsuka, T.	PDF	N/A	Estimating the mean: behavioral and neural correlates of summary representations for time intervals
掘土水鼠犁鼻器的神经解剖学	Ruiz-Rubio, S.	PDF	N/A	Neuroanatomy of the Accessory Olfactory Bulb in the Fossorial Water Vole
预融合AAA+重塑目标-SNARE蛋白复合物能够实现突触传递	White, K. I.	PDF	N/A	Pre-fusion AAA+ remodeling of target-SNARE protein complexes enables synaptic transmission
人脑视觉皮层中的行波：基于模型的MEG-EEG方法	Grabot, L.	PDF	N/A	Traveling Waves in the Human Visual Cortex: a MEG-EEG Model-Based Approach
在Srrm2小鼠中，一种精神分裂症和神经发育障碍的遗传模型，观察到SynGAP-γ的减少、Agap3剪接的破坏以及少突胶质细胞的缺陷。	Aryal, S.	PDF	N/A	Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder
斑马鱼幼鱼中脚间核的解剖和功能组织	Wu, Y. K.	PDF	N/A	Anatomical and functional organization of the interpeduncular nucleus in larval zebrafish
星形胶质细胞的区域特化是由出生后的发育过程塑造的。	Schroeder, M. E.	PDF	N/A	Astrocyte regional specialization is shaped by postnatal development
在自然伸手过程中猕猴前运动皮层神经元的手部位置场	Cao, S.	PDF	N/A	Hand Position Fields of Neurons in the Premotor Cortex of Macaques during Natural Reaching
钾通道亚基Kcnn1在神经元中的过度表达延长了SOD1相关ALS和A53T α-突触核蛋白小鼠模型的生存期	Nagy, M.	PDF	N/A	Neuronal overexpression of potassium channel subunit Kcnn1 prolongs survival of SOD1-linked ALS and A53T alpha-synuclein mouse models
可卡因的摄入和渴求在多巴胺神经元中产生不同的转录组特征	Pollock, T. A.	PDF	N/A	Cocaine taking and craving produce distinct transcriptional profiles in dopamine neurons
在蝗虫中，衰老会减缓去极化扩散的恢复，而抗氧化剂治疗则会加速其恢复。	Robertson, M.	PDF	N/A	Recovery from Spreading Depolarization is slowed by aging and accelerated by antioxidant treatment in locusts
实时预测和相位靶向脑振荡	Jongejan, S. L.	PDF	N/A	Predicting and phase targeting brain oscillations in real-time
深度生成网络揭示了颞下皮层（IT）神经元的调谐特性，并预测了它们对视觉感知的影响。	Papale, P.	PDF	N/A	Deep generative networks reveal the tuning of neurons in IT and predict their influence on visual perception
空间转录组学与免疫荧光染色的整合揭示了实验性胶质母细胞瘤中星形胶质细胞的空间异质性和可塑性	Ghosh, M.	PDF	N/A	Integration of spatial transcriptomics with immunofluorescence staining reveals spatial heterogeneity and plasticity of astrocytes in experimental glioblastomas
星形胶质细胞中HIV-1 Nef的表达降低了伏隔核中谷氨酸转运蛋白的表达，并增加了大鼠的可卡因寻求行为。	Pla-Tenorio, J.	PDF	N/A	Astrocytic HIV-1 Nef expression decreases glutamate transporter expression in the nucleus accumbens and increases cocaine-seeking behavior in rats
光学相干断层扫描能够对中风病变中的细胞移植引导重塑进行纵向评估。	Adewumi, H. O.	PDF	N/A	Optical coherence tomography enables longitudinal evaluation of cell graft-directed remodeling in stroke lesions
阿尔茨海默病中线粒体功能障碍是由患者来源神经元中过量的内质网钙释放驱动的	Mustaly-Kalimi, S.	PDF	N/A	Mitochondrial Dysfunction in Alzheimer's Disease Is Driven By Excess ER-Calcium Release in Patient-Derived Neurons
大细胞、小细胞和视锥细胞通路中空间总和的特征	Wu, C. S.	PDF	N/A	Characteristics of spatial summation in the magnocellular, parvocellular, and koniocellular pathways
黑皮质素4受体依赖的ACTH机制在预防早期生活癫痫后的焦虑样行为和正常化星形胶质细胞蛋白中的作用	Khalife, M. R.	PDF	N/A	Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins After Early Life Seizures
人类可卡因使用障碍中腹侧纹状体的多组学和细胞类型特异性特征	Zillich, E.	PDF	N/A	A multi-omics and cell type-specific characterization of the ventral striatum in human cocaine use disorder
重新编程的人侧脑室旁隆起前体细胞生成纹状体神经元并在亨廷顿病大鼠模型中恢复运动功能。	McCaughey-Chapman, A.	PDF	N/A	Reprogrammed Human Lateral Ganglionic Eminence Precursors Generate Striatal Neurons and Restore Motor Function in a Rat Model of Huntington's Disease.
小脑攀爬纤维传递灵活、快速适应的奖励预测信号	Vignali, C.	PDF	N/A	Cerebellar climbing fibers signal flexible, rapidly adapting reward predictions
沿着不同视觉通路学习的独特的皮层空间表征	Lian, Y.	PDF	N/A	Distinct cortical spatial representations learned along disparate visual pathways
人类的BNST体积并非仅仅是两性异形的。	Berry, S. C.	PDF	N/A	Human BNST volume is not simply sexually dimorphic
上下文依赖偏好中重复的作用	Wagner, B. J.	PDF	N/A	The role of repetition in context-dependent preference
外周给药的TNF抑制剂对α-突触核蛋白诱导的大鼠多巴胺能神经元死亡无保护作用	Christiansen, J. R.	PDF	N/A	Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats
RIPK2对于小胶质细胞对细菌胞壁酰二肽的炎症反应至关重要，但对脂多糖的炎症反应则不然。	Yang, C.	PDF	N/A	RIPK2 is crucial for the microglial inflammatory response to bacterial muramyl dipeptide but not to lipopolysaccharide
AML体内靶向的整合型scFv鉴定与CAR T细胞生成	Müller-Tidow, C.	PDF	N/A	Integrated scFv identification and CAR T cell generation for AML targeting in vivo
通过降解糖免疫检查点Siglec-7和-9来重塑肿瘤微环境	Wang, C.	PDF	N/A	Reshaping the tumor microenvironment by degrading glycoimmune checkpoints Siglec-7 and -9
在拟南芥转座元件中揭示的DNA甲基化与H3K27me3之间的全新串扰	Hure, V.	PDF	N/A	Novel crosstalk between DNA methylation and H3K27me3 revealed at Arabidopsis transposable elements
map3k1抑制了迁移性眼原基在涡虫再生中的终末分化	Lo, K. C.	PDF	N/A	map3k1 suppresses terminal differentiation of migratory eye progenitors in planarian regeneration
在家族性肌萎缩性侧索硬化症4型中，对显性SETX突变进行等位基因特异性沉默	Winkelsas, A.	PDF	N/A	Allele-specific silencing of a dominant SETX mutation in familial amyotrophic lateral sclerosis type 4
新皮层分化与海马体对无意义物品及其空间位置的整合	Nemecz, Z.	PDF	N/A	Neocortical differentiation and hippocampal integration of non-meaningful items and their spatial location
# BioRxiv 2024-10-11 Papers

标题	作者	PDF链接	代码仓库	Title
GEARBOCS：一种用于星形胶质细胞体内基因编辑的腺相关病毒工具	Sivadasan Bindu, D.	PDF	N/A	GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
系统性创建和表型分析在秀丽隐杆线虫中的孟德尔疾病模型：迈向大规模药物再利用	O'Brien, T. J.	PDF	N/A	Systematic creation and phenotyping of Mendelian disease models in C. elegans: towards large-scale drug repurposing
SIMVI揭示了空间组学数据中的内在状态和空间诱导状态	Dong, M.	PDF	N/A	SIMVI reveals intrinsic and spatial-induced states in spatial omics data
通过顺序采样构建价值解释了决策中的序列依赖性	Zylberberg, A.	PDF	N/A	Value construction through sequential sampling explains serial dependencies in decision making
年轻和年长成人在注意定向期间的心跳诱发电位	Aprile, F.	PDF	N/A	The heartbeat-evoked potential in young and older adults during attention orienting
针对异染色质消除恶性干细胞通过重新激活逆转录元件和先天免疫途径在慢性粒单核细胞白血病中的作用	Hidaoui, D.	PDF	N/A	Targeting Heterochromatin Eliminates Malignant Stem Cells in Chronic Myelomonocytic Leukemia Through Reactivation of Retroelements and Innate Immune pathways
查尔酮和吡唑啉衍生物的合成及其作为ELF3-MED23相互作用新型抑制剂的生物学评估	Hwang, S.-Y.	PDF	N/A	Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction
AlphaFold2在二聚体、三聚体和四聚体卷曲螺旋结构域建模中的适用性	Madaj, R.	PDF	N/A	Applicability of AlphaFold2 in the modeling of dimeric, trimeric, and tetrameric coiled-coil domains
异质性和高阶皮质连接支撑着高效、稳健且可靠的神经编码。	Egas Santander, D.	PDF	N/A	Heterogeneous and higher-order cortical connectivity undergirds efficient, robust and reliable neural codes
一种分子开关调控着人类信使RNA的核外输出	Hohmann, U.	PDF	N/A	A molecular switch orchestrates the nuclear export of human messenger RNA
视觉识别深度神经网络的反复问题	Maniquet, T.	PDF	N/A	Recurrent issues with deep neural networks of visual recognition
在尖峰神经肌肉模型中，平衡中央控制与感觉反馈能产生适应性强且稳健的蝾螈脊髓运动模式。	Pazzaglia, A.	PDF	N/A	Balancing central control and sensory feedback produces adaptable and robust locomotor patterns in a spiking, neuromechanical model of the salamander spinal cord
拉特伦库利德海绵中独特而神秘的螺旋体共生体	Waterworth, S. C.	PDF	N/A	The unique and enigmatic spirochete symbiont of latrunculid sponges
模拟显示，法尼醇X受体（FXR）铰链在FXR-RXR核受体异二聚体中扮演着独特的角色。	Yu, T.	PDF	N/A	Simulations reveal unique roles for the FXR hinge in the FXR-RXR nuclear receptor heterodimer
线粒体功能障碍：揭示溃疡性结肠炎期间抗TNF反应背后的生物学机制	Kioroglou, D.	PDF	N/A	Mitochondrial dysfunction: unraveling the elusive biology behind anti-TNF response during ulcerative colitis
在异源二倍体和四倍体群体中，基因组预测杂种优势、近交控制及配对分配	Endelman, J. B.	PDF	N/A	Genomic prediction of heterosis, inbreeding control, and mate allocation in outbred diploid and tetraploid populations
巨噬细胞中脂肪酸的摄入或分解代谢受损会限制结核分枝杆菌的胞内生长。	Simwela, N. V.	PDF	N/A	Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis
蛋白质表面化学编码了一种对干燥的适应性耐受性	Romero-Perez, P. S.	PDF	N/A	Protein Surface Chemistry Encodes an Adaptive Tolerance to Desiccation
含有强效LILRB1 D1D2的抗体可抑制RIFIN介导的免疫逃避	Wang, Y.	PDF	N/A	Potent LILRB1 D1D2-containing antibodies inhibit RIFIN-mediated immune evasions
SynDRep：一种基于协同伙伴预测的药物重定位知识图谱增强工具	Shalaby, K. S.	PDF	N/A	SynDRep: A Knowledge Graph-Enhanced Tool based on Synergistic Partner Prediction for Drug Repurposing
重新思考大规模系统基因组学：PhyloToL 6，一个灵活的工具包，用于实现基于系统发育的数据管理和分析	Cote-L'Heureux, A. E.	PDF	N/A	Rethinking large scale phylogenomics with PhyloToL 6, a flexible toolkit to enable phylogeny-informed data curation and analysis
旁分泌拯救MYR1缺陷型刚地弓形虫突变体揭示了体内CRISPR筛选的局限性	Torelli, F.	PDF	N/A	Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens
大型丝氨酸整合酶脱靶发现与验证用于治疗性基因组编辑	Hazelbaker, D. Z.	PDF	N/A	Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing
利用跨试验和行为会话的相关性来改进神经解码	Zhang, Y.	PDF	N/A	Exploiting correlations across trials and behavioral sessions to improve neural decoding
使用深度学习和基于物理的专家混合进行稳健的RNA二级结构预测	Qiu, X.	PDF	N/A	Robust RNA Secondary Structure Prediction with a Mixture of Deep Learning and Physics-based Experts
前额叶皮层中的视觉运动神经元进行的贝叶斯推理	Langlois, T.	PDF	N/A	Bayesian inference by visuomotor neurons in prefrontal cortex
模块化表示出现在经过训练以执行依赖于上下文的任务的神经网络中	Johnston, W. J.	PDF	N/A	Modular representations emerge in neural networks trained to perform context-dependent tasks
动物声学交流保持着一种普遍的最优节奏	Piette, T.	PDF	N/A	Animal acoustic communication maintains a universal optimum rhythm
生物信息学：整合负对照以获得优质数据	van Nues, R. W.	PDF	N/A	Bio-informatics: Integrate negative controls to get the good data
哥伦比亚大西洋省韦莱罗港高沉积物水域中珊瑚种群及其相关生物的空前发现	Moreno Tilano, J. A.	PDF	N/A	Unprecedented sighting of coral populations and associated fauna in the High Sedimentation Waters of Puerto Velero, Atlantico, Colombia
雌激素缺乏改变血管化和矿化动力学：来自新型三维人源化和血管化骨类器官模型的见解	Bukhari, M. M. M.	PDF	N/A	Estrogen Deficiency alters Vascularization and Mineralization dynamics: insight from a novel 3D Humanized and Vascularized Bone Organoid Model
剖析人类诱导多能干细胞模型中MASLD进展过程中的复合肝细胞损伤	Weihs, J.	PDF	N/A	Dissecting compounded hepatocyte injury in a model of MASLD progression from human induced pluripotent stem cells
小GTP酶Ran定义了核孔复合物的非对称性。	Sachweh, J.	PDF	N/A	The small GTPase Ran defines Nuclear Pore Complex asymmetry
cGAS缺陷小鼠表现出与LINE1元件去抑制和炎症相关的早衰现象。	Martinez, J. C.	PDF	N/A	cGAS deficient mice display premature aging associated with de-repression of LINE1 elements and inflammation
一种非典型的E3泛素连接酶在营养压力期间保护核糖体	Douglas, T.	PDF	N/A	An atypical E3 ligase safeguards the ribosome during nutrient stress
BBSome的功能多样化：来自蜜蜂锥虫寄生虫Lotmaria passim的见解	Yuan, X.	PDF	N/A	Functional diversification of the BBSome: Insights from honey bee trypanosomatid parasite, Lotmaria passim
Plexin/Semaphorin拮抗作用通过接触间充质化调控集体细胞迁移、间隙闭合和器官塑形	Bischoff, M. C.	PDF	N/A	Plexin/Semaphorin Antagonism Orchestrates Collective Cell Migration, Gap Closure and Organ sculpting by Contact-Mesenchymalization
Nth-like DNA糖基化酶对线粒体动力学的影响	Hubers, L. A.	PDF	N/A	Functional Impact of Nth-like DNA glycosylase on Mitochondrial Dynamics
GPR87在肺纤维化中的作用	Khoury, J.	PDF	N/A	The role of GPR87 in Pulmonary Fibrosis
Danicamtiv通过减少肌球蛋白的工作冲程，同时激活细丝来增强收缩。	Scott, B.	PDF	N/A	Danicamtiv reduces myosin's working stroke but enhances contraction by activating the thin filament
配体结合的TRPV1异质性：冷冻电镜与分子动力学模拟方法的比较	Astore, M. A.	PDF	N/A	Heterogeneity in ligand-bound TRPV1: A comparison of methods in cryo-EM and molecular dynamics simulation
骨髓基质细胞之间的隧道纳米管支持传递自噬和多发性骨髓瘤的抗凋亡作用。	Solimando, A. G.	PDF	N/A	Tunneling Nanotubes Between Bone Marrow Stromal Cells Support Transmitophagy and Resistance to Apoptosis in Myeloma
绘制接受氟达拉滨治疗的白血病细胞的空间蛋白质组图谱	Globisch, M. A.	PDF	N/A	Mapping the Spatial Proteome of Leukemia Cells Undergoing Fludarabine Treatment
细胞外谷胱甘肽的分解代谢为肿瘤生长提供了氨基酸支持。	Hecht, F.	PDF	N/A	Catabolism of extracellular glutathione supplies amino acids to support tumor growth
一项大规模的反向遗传学筛选鉴定出多个调控睾丸新生肌管集体细胞迁移和集体器官塑形的调控因子	Bischoff, M. C.	PDF	N/A	A large reverse-genetic screen identifies numerous regulators of testis nascent myotube collective cell migration and collective organ sculpting
货物适配器身份控制驱动蛋白激活的机制和动力学	Gillies, J. P.	PDF	N/A	Cargo adaptor identity controls the mechanism and kinetics of dynein activation
FUDR的磷酰胺酸修饰物NUC-3373，可导致结直肠癌细胞DNA损伤并释放损伤相关分子模式（DAMPs），从而增强淋巴细胞诱导的细胞死亡。	read, o.	PDF	N/A	A phosphoramidate modification of FUDR, NUC-3373, causes DNA damage and DAMPs release from colorectal cancer cells, potentiating lymphocyte-induced cell death
从福尔马林固定石蜡包埋（FFPE）样本中进行可靠的RNA测序分析，作为加速癌症相关健康差异研究的一种手段	Sandulache, V.	PDF	N/A	Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research
从福尔马林固定石蜡包埋（FFPE）样本中进行可靠的RNA测序分析，作为加速癌症相关健康差异研究的一种手段	Sandulache, V.	PDF	N/A	Reliable RNA-seq analysis from FFPE specimens as a means to accelerate cancer-related health disparities research
甲状腺癌中可靶向治疗的耐药性与克隆性造血相关	Tiedje, V.	PDF	N/A	Targetable Treatment Resistance in Thyroid Cancer with Clonal Hematopoiesis
富含多酚的岩白菜（Bergenia ligulata (Wall.) Engl.）提取物在体内增强结肠和乳腺癌转移：细胞类型特异性机制的证据	De, S.	PDF	N/A	Polyphenol-rich fraction of Bergenia ligulata (Wall.) Engl. sensitizes colon and breast cancer metastasis in vivo: Evidence of cell-type specific mechanism
易位可以驱动调控子中多个基因的表达变化，这些调控子覆盖整个染色体臂。	Oncins, A.	PDF	N/A	Translocations can drive expression changes of multiple genes in regulons covering entire chromosome arms
PKCtheta-GADD45a轴的丧失促使三阴性乳腺癌细胞进入p53非依赖性衰老状态。	Nicolle, A.	PDF	N/A	Loss of PKCtheta-GADD45a axis drives triple-negative breast cancer cells into p53-independent senescence
CXCR4部分激动剂通过靶向多形核髓源性抑制细胞和癌症驱动的粒细胞生成，改善了免疫疗法的效果。	Qian, J.	PDF	N/A	A CXCR4 partial agonist improves immunotherapy by targeting polymorphonuclear myeloid-derived suppressor cells and cancer-driven granulopoiesis
基于性别和年龄的小鼠原代腹膜间皮细胞蛋白质组特征分析与比较	Wang, Z.	PDF	N/A	Gender- and Age-Based Characterization and Comparison of the Murine Primary Peritoneal Mesothelial Cell Proteome
癌症mRNA翻译特异性介质的筛选	Kovalski, J. R.	PDF	N/A	Functional screen for mediators of onco-mRNA translation specificity
别构降解剂诱导CRL5ASB8介导的XPO1降解	Hudman-Wing, C. E.	PDF	N/A	Allosteric degraders induce CRL5ASB8 mediated degradation of XPO1
利用胰凝乳蛋白酶水解法挖掘人类卵巢癌外泌体的蛋白质组	Cooper, T. T.	PDF	N/A	Mining the Proteome of Human Ovarian Cancer Extracellular Vesicles Using Thermolysin Proteolysis
胰岛素抵抗性肥胖中的血浆外泌体加剧三阴性乳腺癌的进展	Llevenes, P.	PDF	N/A	Plasma Exosomes in Insulin Resistant Obesity Exacerbate Progression of Triple Negative Breast Cancer
Mgat4b介导的选择性N-糖基化调控黑素细胞发育及黑色素瘤进展	Natarajan, V. T.	PDF	N/A	Mgat4b mediated selective N-glycosylation regulates melanocyte development and melanoma progression
一种肿瘤胚胎学方法揭示了SoxC驱动的结肠发育和癌症调控	Dalessi, T.	PDF	N/A	An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer
H2AK119ub动力学控制毛囊干细胞静息状态	Flora, P.	PDF	N/A	H2AK119ub dynamics controls hair follicle stem cell quiescence
人类和大猩猩视网膜蓝锥光感受器外节中的全长隐花色素1表明其作用不仅仅局限于转录抑制。	Bartoelke, R.	PDF	N/A	Full-length Cryptochrome 1 in the outer segments of the retinal blue cone photoreceptors in humans and great apes suggests a role beyond transcriptional repression
一种结直肠癌中三级淋巴结构数字表征的新方法	Munoz-Erazo, L.	PDF	N/A	A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer
鉴定DLK1（一种Notch配体）作为免疫治疗靶点及调节肾上腺皮质癌肿瘤细胞可塑性和化学抗性的作用	Sun, N.-Y.	PDF	N/A	Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma
由于谱系依赖的干细胞和祖细胞上的生长抑素受体表达，放射性诊断概念在神经内分泌肿瘤中的局限性	Nguyen, N.	PDF	N/A	Limitations of the radiotheranostic concept in neuroendocrine tumors due to lineage-dependent somatostatin receptor expression on hematopoietic stem and progenitor cells
抑制雄激素受体暴露了前列腺癌的复制应激脆弱性	Williams, C. S.	PDF	N/A	Inhibition of Androgen Receptor Exposes Replication Stress Vulnerability in Prostate Cancer
遗传数据指导下的卵巢癌最佳治疗方案	Mertzios, A.	PDF	N/A	Optimal Prescriptive Treatments for Ovarian Cancer with Genetic Data
从年轻和年老小鼠中建立永生化的棕色和白色前脂肪细胞系	Wu, X.	PDF	N/A	Establishing immortalized brown and white preadipocyte cell lines from young and aged mice
一种新型GelMA-OrnMA电导性生物墨水用于开发工程化神经组织	Sakr, M.	PDF	N/A	A Novel GelMA-OrnMA Electrically Conductive Bioink for Developing Engineered Neural Tissues
解开金丝桃素的潜力：一种针对胆固醇管理中PCSK9突变的新方法	FERRARI, I. V.	PDF	N/A	Unraveling the Potential of Hypericin: A Novel Approach to Targeting PCSK9 Mutations in Cholesterol Management
基准测试基于序列和基于AlphaFold的方法用于pMHC-II结合核心预测：各自的优势与共识方法	Ko, S.	PDF	N/A	Benchmarking Sequence-Based and AlphaFold-Based Methods for pMHC-II Binding Core Prediction: Distinct Strengths and Consensus Approaches
利用预测的噬菌体宿主信息改进肠道噬菌体群落比较	Shamash, M.	PDF	N/A	Improving gut virome comparisons using predicted phage host information
蛋白质聚集以特定尺寸的方式驱动大肠杆菌细胞的衰老	Wagener, L.	PDF	N/A	Protein aggregation drives cell aging in a size-specific manner in Escherichia coli
在魏斯曼式和拉马克式继承的连续体上，文化复制的一个达尔文模型	Zachar, I.	PDF	N/A	A Darwinian model of cultural replication over the continuum of Weismannian and Lamarckian inheritance
不同血管区对脑自动调节和功能性充血的深度依赖性贡献：一项模拟分析	Pashaie, R.	PDF	N/A	Depth-Dependent Contributions of Various Vascular Zones to Cerebral Autoregulation and Functional; Hyperemia: An In-Silico Analysis
提高生成化学中分子字符串表示的可靠性	Reboul, E.	PDF	N/A	Improving the reliability of molecular string representations for generative chemistry
数据驱动评估适用于改进抗体选择的合适免疫原	Waury, K.	PDF	N/A	Data-driven evaluation of suitable immunogens for improved antibody selection
Vispro 提升了 Visium 空间转录组学成像分析的效果。	Ma, H.	PDF	N/A	Vispro improves imaging analysis for Visium spatial transcriptomics
揭示新型高糖基化人促红细胞生成素类似物：全面计算探索	Thahsin, N.	PDF	N/A	Unveiling Novel Hyperglycosylated Analog of Human Erythropoietin: A Comprehensive Computational Exploration
迈向更环保的AlphaFold2蛋白质复合物建模协议：来自CAPRI第55轮的见解	Savas, B.	PDF	N/A	Towards a greener AlphaFold2 protocol for protein complex modeling: Insights from CAPRI Round 55
R3DFEM：一个用于运行3D-CMCC-FEM模型的R包	Vangi, E.	PDF	N/A	R3DFEM: an R package for running the 3D-CMCC-FEM model
定量分析Hsp100蛋白解聚酶在折叠蛋白底物上的进程性	Banwait, J. K.	PDF	N/A	Quantitative Insights into Processivity of an Hsp100 Protein Disaggregase on Folded Protein Substrates
基于强化学习的加权集成方法的罕见事件采样	Yang, D.	PDF	N/A	Rare-Event Sampling using a Reinforcement Learning-Based Weighted Ensemble Method
与加速亨廷顿病进展相关的FAN1点突变改变了其在DNA上的PCNA介导的组装	Aretz, J.	PDF	N/A	A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA
嗜酸性粒细胞主要碱性蛋白-1的原位晶体结构	Yang, J. E.	PDF	N/A	In situ crystalline structure of the Eosinophil major basic protein-1
编织DNA的几何结构决定了超螺旋的分布	Hong, Y.	PDF	N/A	Geometry of Braided DNA Dictates Supercoiling Partition
无序蛋白质：微相还是关联聚合物？	Girard, M.	PDF	N/A	Disordered proteins: microphases or associative polymers?
通过深度学习和协同进化分析揭示的细胞质苹果酸脱氢酶的热适应性	Shukla, D.	PDF	N/A	Thermal Adaptation of Cytosolic Malate Dehydrogenase Revealed by Deep Learning and Coevolutionary Analysis
细胞穿透肽对膜破坏的计算研究	Catalina-Hernandez, E.	PDF	N/A	Computational Insights into Membrane Disruption by Cell-Penetrating Peptides
生物膜上的质子迁移：脂质相、温度及成分对质子传递过程及膜质子屏障的依赖性	Ramanthrikkovil Variyam, A.	PDF	N/A	Proton migration on biological membranes: Lipid phase, temperature, and composition dependence of proton transfer processes and membrane proton barrier
我们能否开发出理想的RNA力场？从UUCG RNA四核苷酸环及其他系统的模拟中获得的启示。	Mlynsky, V.	PDF	N/A	Can We Ever Develop an Ideal RNA Force Field? Lessons Learned from Simulations of UUCG RNA Tetraloop and Other Systems.
内在无序蛋白质的序列-集合-功能关系的广义设计	Krueger, R.	PDF	N/A	Generalized design of sequence-ensemble-function relationships for intrinsically disordered proteins
混合蛋白质溶液中的扩散与粘度	Wozniak, S.	PDF	N/A	Diffusion and Viscosity in Mixed Protein Solutions
Afadin 介导了与协同结合和肌动蛋白丝曲率相关的 F-肌动蛋白上的钙粘蛋白-连环蛋白复合物的聚集。	Gong, R.	PDF	N/A	Afadin mediates cadherin-catenin complex clustering on F-actin linked to cooperative binding and filament curvature
阿片受体揭示了一种明确的细胞内机制，即内体G蛋白的激活	Fisher, N. M.	PDF	N/A	Opioid receptors reveal a discrete cellular mechanism of endosomal G protein activation
通过植物RNA热敏开关控制异源蛋白合成	Lastovka, F.	PDF	N/A	Controlling heterologous protein synthesis through a plant RNA ThermoSwitch
杏仁核亚区体积及分配在青春期前儿童中的情况——与年龄、性别和体重指数的关联	Overholtzer, L. N.	PDF	N/A	Amygdala Subregion Volumes and Apportionment in Preadolescents -- Associations with Age, Sex, and Body Mass Index
与亚临床性淡漠相关的前额叶-运动回路	Derosiere, G.	PDF	N/A	Fronto-motor circuits linked to subclinical apathy
LPS结合的胱天蛋白酶激活和募集结构域（CARDs）是二分体的脂质结合模块。	Cao, A. B.	PDF	N/A	LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules
抗体-Fab和-Fc特性促进结核分枝杆菌的限制。	Grace, P. S.	PDF	N/A	Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction.
巨细胞病毒与脑萎缩在不同人群中免疫衰老轨迹的关系	Touil, H.	PDF	N/A	Relation of CMV and brain atrophy to trajectories of immunosenescence in diverse populations
铜绿假单胞菌中葡糖胺基磷脂酰甘油的生物合成	Khan, F. Z.	PDF	N/A	Biosynthesis of glucosaminyl phosphatidylglycerol in Pseudomonas aeruginosa
跨代效应改变了表型可塑性的适应性后果及其调控途径的遗传结构	Bogan, S. N.	PDF	N/A	Transgenerational effects alter the fitness consequences and genetic architecture of phenotypic plasticity and its regulatory pathways
良好的系统发育分析揭示了蝶形花科豆科植物多样化过程中龙骨瓣花的多次起源。	Cai, L.	PDF	N/A	Well-resolved phylogeny reveals multiple origins of keel flowers during the diversification of papilionoid legumes
完整的参考基因组和泛基因组扩展了使用短读长测序和阵列数据进行全基因组DNA甲基化分析的生物学相关信息	Dong, Z.	PDF	N/A	Complete Reference Genome and Pangenome Expand Biologically Relevant Information for Genome-Wide DNA Methylation Analysis Using Short-Read Sequencing and Array Data
染色体水平的高分辨率单倍型解析基因组组装为深入了解意大利黑麦草（Lolium multiflorum Lam.）的高度杂合基因组提供了见解。	Chen, Y.	PDF	N/A	Chromosome-level haplotype-resolved genome assembly provides insights into the highly heterozygous genome of Italian ryegrass (Lolium multiflorum Lam.)
评估一种高通量质谱方法，利用体积吸收微采样（VAMS）设备加速临床癌症队列中的生物标志物发现。	Lucas, N.	PDF	N/A	Assessment of a high-throughput mass spectrometry method to accelerate biomarker discovery in clinical cancer cohorts using volumetric absorptive microsampling (VAMS) devices.
ProFit-1D用于在3T磁场下量化J差异编辑数据	Chan, K. L.	PDF	N/A	ProFit-1D for quantifying J-difference edited data at 3T
使用从头设计的激动剂调整胰岛素受体信号传导	Wang, X.	PDF	N/A	Tuning Insulin Receptor Signaling Using De Novo Designed Agonists
纳米抗体表位预测中的AI驱动方法：我们是否已经到达？	Eshak, F.	PDF	N/A	AI driven approaches in Nanobody Epitope Prediction: Are We There Yet?
构建：一种用于识别蛋白质三级结构中功能性或结构重要区域的算法工具	Chivot, L.	PDF	N/A	CONSTRUCT: an algorithmic tool for identifying functional or structurally important regions in protein tertiary structure
LipiDetective - 一种用于在串联质谱中识别分子脂质种类的深度学习模型	Wuerf, V.	PDF	N/A	LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra
可解释的多组学整合：基于UMAP嵌入和密度聚类的分析	Castellano-Escuder, P.	PDF	N/A	Interpretable multi-omics integration with UMAP embeddings and density-based clustering
阿波罗：一种综合性的基于主机的GPU加速模拟器，用于模拟病毒进化和感染动力学在人群、组织和细胞间的传播过程。	Perera, D.	PDF	N/A	Apollo: A comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell
精氨酸甲基化与磷酸化协同作用，调控NADP+的合成	Zhu, Y.	PDF	N/A	Arginine methylation coordinates with phosphorylation to regulate NADP+ synthesis
基于RSPO4的靶向LGR4/5/6的喜树碱类似物偶联物在结直肠癌临床前模型中的抗肿瘤活性研究。	Toh, Y.	PDF	N/A	Anti-tumor activity of camptothecin analog conjugate of a RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.
体内双光子荧光寿命成像技术解析了玉米维管束鞘细胞的光合特性	Chen, Z.	PDF	N/A	In vivo two-photon FLIM resolves photosynthetic properties of maize bundle sheath cells
肌联蛋白H样蛋白条件性缺失对心脏功能的影响。	Burnham, H. V.	PDF	N/A	The effects of conditional loss of myosin binding protein H-like on cardiac function.
利用量子点纳米颗粒追踪活体内促性腺激素释放激素介导的运动：对精子释放途径的深入了解	Julien, A. R.	PDF	N/A	Tracking gonadotropin-releasing hormone-mediated movement in-vivo using quantum dot nanoparticles: insights into pathways leading to sperm release
成熟树干钻孔处理前后树液流速的空间变化	Umebayashi, T.	PDF	N/A	Spatial variations in sap flow rates in mature tree stems before and after drilling treatment
单细胞RNA测序数据在预测植物代谢途径基因中的应用	Ma, J.	PDF	N/A	The utility of single-cell RNA sequencing data in predicting plant metabolic pathway genes
植物抵抗丁香假单胞菌的抗性中，水分免疫优先于气孔免疫。	Kemppinen, J.	PDF	N/A	Water immunity overrides stomatal immunity in plant resistance to Pseudomonas syringae
NPF4.1 将胚胎衍生的 GA4 导入胚乳，以促进种子萌发	Sirlin-Josserand, M.	PDF	N/A	NPF4.1 imports embryo-derived GA4 to the endosperm to promote seed germination
计算微生物组药理学分析阐明了阴道微生物及其代谢物的抗癌潜力	Lawore, D. C.	PDF	N/A	Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites
成人生命周期中成功视觉短时记忆的多个神经通路	Jansen, M. G.	PDF	N/A	Multiple neural pathways to successful visual short-term memory across the adult lifespan
在人类内侧前额叶皮层中，随着巩固过程的进行，一个抽象的关系图谱逐渐显现。	Baram, A.	PDF	N/A	An abstract relational map emerges in the human medial prefrontal cortex with consolidation
扩展数学框架以研究在存在小胶质细胞包绕情况下的神经元动力学	Garcia, N.	PDF	N/A	Extending mathematical frameworks to investigate neuronal dynamics in the presence of microglial ensheathment
多巴胺和皮质iPSC衍生的神经元在不同的帕金森病突变中表现出溶酶体和线粒体功能障碍的差异：这对蛋白质沉积与选择性细胞丢失的意义	Chedid, J.	PDF	N/A	Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
口服避孕药对大脑网络的影响：一项重复和扩展研究	Haase, G.	PDF	N/A	Effects of oral contraceptive pills on brain networks: A replication and extension
同位素编码化学成像识别淀粉样斑块年龄依赖性结构成熟、突触丧失及毒性增加	Wood, J. I.	PDF	N/A	Isotope Encoded Chemical Imaging Identifies Amyloid Plaque Age Dependent Structural Maturation, Synaptic Loss, and Increased Toxicity
纵向多组学揭示了TSC2致病变异扰乱了从结节性硬化症复杂病变中衍生的人类皮层类器官的发育轨迹	Niu, W.	PDF	N/A	Longitudinal multi-omics reveals pathogenic TSC2 variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis Complex
长期记忆从优先和非优先状态中提取的工作记忆效果	Born, F.	PDF	N/A	Long-Term Effects of Working Memory Retrieval From Prioritized and Deprioritized States
T-scope V4：用于自由活动动物光遗传标记的微型显微镜	Wang, Y.	PDF	N/A	T-scope V4: miniaturized microscope for optogenetic tagging in freely behaving animals
在灵长类动物的初级视觉皮层（V1）中，外周表征的活动在奔跑过程中会显著地受到调节。	Rowley, D. P.	PDF	N/A	Activity in the peripheral representation within primate V1 is substantially modulated during running
R21/Matrix-M疟疾疫苗诱导的抗体库、功能和结构	McDaniel, J. R.	PDF	N/A	Repertoire, function, and structure of serological antibodies induced by the R21/Matrix-M malaria vaccine
IgG自身抗体在类天疱疮中直接诱导角质形成细胞中依赖于MyD88的促炎性反应，从而导致病理性炎症反应：	Bao, L.	PDF	N/A	IgG autoantibodies in bullous pemphigoid directly induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes:
代谢组学分析揭示脂肪酸在慢性病毒感染期间作为调节干细胞样耗竭CD8 T细胞的潜力	Kazane, K. R.	PDF	N/A	Metabolomic Profiling Reveals Potential of Fatty Acids as Regulators of Stem-like Exhausted CD8 T Cells During Chronic Viral Infection
研究儿童大脑和生物发育及其与身体、心理和学业成果的关系	Chang, H.	PDF	N/A	Investigating Brain and Biological Development in Children and Their Relationship with Physical, Mental, and Academic Outcomes
降水变化驱动草原功能群间相互作用及短期瞬时不稳定性的差异：一种基于阶段结构群落的方法	Gupta, A.	PDF	N/A	Variation in precipitation drives differences in interactions and short-term transient instability between grassland functional groups: a stage-structured community approach
冰川后遗传遗产、人口统计学与气候变化：为银冷杉制定保护优先事项	Balao, F.	PDF	N/A	Postglacial Genetic Legacies, Demography, and Climate Change: Setting Conservation Priorities for Silver Fir
软组织体积对骨骼气腔化程度估计的影响：对古鸟类动物的启示	Burton, M. G.	PDF	N/A	The influence of soft tissue volume on estimates of skeletal pneumaticity: implications for fossil archosaurs
TP53 微基因分析的 161 个序列变化提供了空间约束和调控元件对变异诱导剪接影响的证据。	Canson, D. M.	PDF	N/A	TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact
吞噬作用中的蛋白激酶：癌症的潜在遗传生物标志物	Arumilli, S.	PDF	N/A	Protein Kinases in Phagocytosis: Promising Genetic Biomarkers for Cancer
基于组织异质性的对比增强光学相干弹性成像在乳腺癌可视化中的应用	Li, J.	PDF	N/A	Visualization of breast cancer using contrast-enhanced optical coherence elastography based on tissue heterogeneity
基准测试用于抗体设计的生成模型	Ucar, T.	PDF	N/A	Benchmarking Generative Models for Antibody Design
InteracTor：一种新的综合特征提取工具包，用于改进蛋白质结构性质的表征	Silva, J. C. F.	PDF	N/A	InteracTor: A new integrative feature extraction toolkit for improved characterization of protein structural properties
鉴定葡萄膜黑色素瘤中可靶向的表观遗传脆弱性	Yenisehirli, G.	PDF	N/A	Identification of targetable epigenetic vulnerabilities in uveal melanoma
解决深度学习中的领域偏移问题：从植物病害诊断和花卉识别中获得的挑战与见解	Sun, J.	PDF	N/A	Addressing domain shift in deep learning: Challenges and insights from plant disease diagnosis and flower recognition
基于随机化的不同拓扑和癌症表达特征的相互作用基因对的评估	Dalgic, E.	PDF	N/A	Randomization based evaluation of distinct topological and cancer expression characteristics of mutually acting gene pairs
使用多传感器地理定位器和稳定同位素揭示的高纬度繁殖鸣禽（Setophaga coronata coronata）的迁徙策略	Szarmach, S. J.	PDF	N/A	Migration strategies of a high-latitude breeding songbird (Setophaga coronata coronata) revealed using multi-sensor geolocators and stable isotopes
研究合生干预对健康年轻女性工作记忆表现的影响	Salimi, Y.	PDF	N/A	Investigating the Effects of Synbiotic Intervention on Working Memory performance in Healthy Young Women
ORCO：Ollivier-Ricci曲率-组学：一种用于分析生物系统鲁棒性的无监督方法	Simhal, A. K.	PDF	N/A	ORCO: Ollivier-Ricci Curvature-Omics: an unsupervised method for analyzing robustness in biological systems
基于pA-Tn5插入模式的TIP-seq峰值调用参数的合理设计提高了预测能力	Roberts, T.	PDF	N/A	Rational design of peak calling parameters for TIP-seq based on pA-Tn5 insertion patterns improves predictive power
全基因组CRISPR/Cas9筛选揭示影响肿瘤细胞对NK细胞介导杀伤敏感性的因素	Guia, S.	PDF	N/A	Genome-wide CRISPR/Cas9 screen reveals factors that influence the susceptibility of tumor cells to NK cell-mediated killing
头孢吡肟-他尼巴坦和头孢布坦-莱达巴坦对导致头孢他啶-阿维巴坦耐药的KPC变异株保持活性	Myers, C. L.	PDF	N/A	Cefepime-Taniborbactam and Ceftibuten-Ledaborbactam Maintain Activity Against KPC Variants that Lead to Ceftazidime-Avibactam Resistance
MEDOC：一种快速、可扩展且在数学上精确的算法，用于在大规模无序蛋白质中进行位点特异性的质子化程度预测	Fossat, M. J.	PDF	N/A	MEDOC: A fast, scalable and mathematically exact algorithm for the site-specific prediction of the protonation degree in large disordered proteins
对SARS-CoV-2核衣壳C端结构域RNA结合抑制剂的结构见解	Dhaka, P.	PDF	N/A	Structural insights into the RNA binding inhibitors of the C-terminal domain of the SARS-CoV-2 nucleocapsid
柴-1：解码生命的分子相互作用	Chai Discovery (Chai),	PDF	N/A	Chai-1: Decoding the molecular interactions of life
小锚蛋白重复蛋白对SARS-CoV-2变种的功能活性与结合特异性	Park, Y.-J.	PDF	N/A	Functional Activity and Binding Specificity of small Ankyron Repeat Proteins against SARS-CoV-2 variants
人类扁桃体类器官揭示了调节ChAdOx1体液和细胞反应的先天通路	Pudjohartono, M. F.	PDF	N/A	Human tonsil organoids reveal innate pathways modulating humoral and cellular responses to ChAdOx1
北极洋病毒群落：季节性、两极性及原核生物相互作用	Calayag, A.	PDF	N/A	Arctic Ocean virus communities: seasonality, bipolarity, and prokaryotic interactions
弧菌可能是欧洲沿海环境中新型粘菌素抗性基因的潜在来源	Saad, J.	PDF	N/A	Vibrio are a potential source of novel colistin-resistance genes in European coastal environments
登革病毒2型感染内皮细胞条件培养基对上皮细胞愈合的影响：活细胞成像分析	Hincapie, V.	PDF	N/A	Effect of inactivated conditioned media from DENV-2-infected endothelial cells on epithelial cell healing: live cell imaging analysis.
代谢重编程通过稳定干扰素-γ诱导的IRF1来影响痘病毒感染的结果	Chang, T.	PDF	N/A	Metabolic reprogramming tips vaccinia virus infection outcomes by stabilizing interferon-g induced IRF1
元基因组覆盖率的差异可能会混淆基于丰度和多样性的结论。	Riquelme, B. A.	PDF	N/A	Differences in metagenome coverage may confound abundance-based and diversity conclusions
鼻内递送一种广泛中和的单域抗体，靶向ACE2，可预防SARS-CoV-2感染。	Blachier, S.	PDF	N/A	Intranasal delivery of a broadly neutralizing single domain antibody targeting ACE2 protects against SARS-CoV-2 infection
新型转基因人源化α-1抗胰蛋白酶缺乏症小鼠模型，基于小鼠SERPINA1基因敲除背景	Oshins, R.	PDF	N/A	Novel Transgenic Humanized Alpha-1 Antitrypsin Deficiency Mouse Model on Murine SERPINA1 Null Background
从Haloferax volcanii中删除前病毒会影响运动性、抗逆性和CRISPR RNA的表达。	Di Cianni, N.	PDF	N/A	Provirus deletion from Haloferax volcanii affects motility, stress resistance and CRISPR RNA expression
RPS19 和 RPL5，钻石黑人贫血症中最常见的突变基因，影响DNA双链断裂修复。	DeCleene, N. F.	PDF	N/A	RPS19 and RPL5, the most commonly mutated genes in Diamond Blackfan anemia, impact DNA double-strand break repair
鉴定单性生殖和雌雄同体海洋鱼类中性二型循环微小RNA。	Geffroy, B.	PDF	N/A	Identifying sexually dimorphic circulating microRNAs in gonochoristic and hermaphroditic marine fish species.
RAD51同源物与RAD51同源物复合物BCDX2和CX3与BRCA2相互作用	Thrasher, J. G.	PDF	N/A	RAD51 Paralogs and RAD51 Paralog Complexes BCDX2 and CX3 Interact with BRCA2
SMYD5是一种核糖体甲基转移酶，通过识别KXY基序，对RPL40赖氨酸22进行三甲基化修饰。	Hamey, J. J.	PDF	N/A	SMYD5 is a ribosomal methyltransferase which trimethylates RPL40 lysine 22 through recognition of a KXY motif
果蝇（Drosophila melanogaster）中对异硫氰酸酯敏感的气味受体及其在食草性近缘物种中的进化扩张	Matsunaga, T.	PDF	N/A	Odorant receptors tuned to isothiocyanates in Drosophila melanogaster and their evolutionary expansion in herbivorous relatives
一组针对果蝇中保守信号配体的分裂Gal4驱动器	Ewen-Campen, B.	PDF	N/A	A collection of split-Gal4 drivers targeting conserved signaling ligands in Drosophila
斑马鱼中rbfox1功能丧失导致bdnf/trkb2和pac1a表达失调，进而引起HPI轴过度激活、应激反应改变以及稳态负荷过重。	Leggieri, A.	PDF	N/A	rbfox1 loss of function in zebrafish leads to dysregulation in bdnf/trkb2 and pac1a expression resulting in HPI axis hyperactivation, altered stress response and allostatic overload
CREB3功能获得性变异可预防ALS	Megat, S.	PDF	N/A	CREB3 gain of function variants protect against ALS
在“狗衰老项目”中，来自多样化犬群的DNA甲基化模式揭示了年龄差异。	Mariner, B. L.	PDF	N/A	DNA methylation of transposons pattern aging differences across a diverse cohort of dogs from the Dog Aging Project
近北极地区的蝙蝠（Myotis bats）具有广泛的寿命和由DNA病毒驱动的适应性。	Vazquez, J. M.	PDF	N/A	Extensive longevity and DNA virus-driven adaptation in nearctic Myotis bats
磷酸蛋白质组学揭示了成纤维细胞在炎症刺激下复杂的资源管理机制	Janker-Bortel, P.	PDF	N/A	Phosphoproteomics highlights complex resource management upon inflammatory stimulation of fibroblasts
扭转性创伤性视神经病变（TITON）：一种生理上相关的创伤性视神经病变动物模型	Ryan, A. K.	PDF	N/A	Torsion-Induced Traumatic Optic Neuropathy (TITON): A Physiologically Relevant Animal Model of Traumatic Optic Neuropathy
通过功能引导的计算机模拟进化将AAV衣壳序列映射到功能	Zheng, H.	PDF	N/A	Mapping AAV capsid sequences to functions through function-guided in silico evolution
深度学习助力在Pharos中发现激酶药物靶点	Halasz, A. M.	PDF	N/A	Deep Learning enabled discovery of kinase drug targets in Pharos
探索Corallococcus属的代谢潜力：丰富的次生代谢产物和CAZymes来源	Hossain, M. S.	PDF	N/A	Exploration of the Metabolic Potential of the Corallococcus Genus: A Rich Source of Secondary Metabolites, and CAZymes
GATA1缺陷型人类多能干细胞生成的嗜中性粒细胞具有增强的抗真菌免疫能力，这种免疫能力是通过整合素CD18介导的。	Wagner, A. S.	PDF	N/A	GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18
在低pH、低温及高渗透压应激条件下，大肠杆菌的生长需要wzxE翻转酶来处理肠杆菌共同抗原中间体。	Yamaguchi, S.	PDF	N/A	Escherichia coli growth under low pH, low temperature, and high osmotic stress conditions requires the wzxE flippase for the enterobacterial common antigen intermediate
系统性、高通量地表征噬菌体基因在不同宿主中的必需性	Chen, J.	PDF	N/A	Systematic, high-throughput characterization of bacteriophage gene essentiality on diverse hosts
火疫病菌欧文氏菌通过苹果叶自然脱落的毛状体伤口进入叶片。	Millett, F.	PDF	N/A	The fire blight pathogen Erwinia amylovora enters apple leaves through naturally-occurring wounds from the abscission of trichomes
多聚腺苷酸化酶PAPI是致病菌中维持毒力质粒所必需的	Schubert, K.	PDF	N/A	The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria
一种用于倾斜系列数据相干功率谱平均以改进CTF估计的方法	Khavnekar, S.	PDF	N/A	An approach for coherent periodogram averaging of tilt-series data for improved CTF estimation
质粒DNA中的人源Fos启动子活性过高	Gorbunov, A.	PDF	N/A	Isolated human Fos promoter in plasmid DNA is overactive
# BioRxiv 2024-10-10 Papers

标题	作者	PDF链接	代码仓库	Title
多切片空间转录组学数据在二维和三维中的自动化整合	Bienroth, D.	PDF	N/A	Automated Integration of Multi-Slice Spatial Transcriptomics Data in 2D and 3D
倒位可以积累平衡的性对抗：来自模拟和果蝇实验的证据	McAllester, C. S.	PDF	N/A	Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments
冬眠会减少脑干中的GABA信号传导，以增强在低温下的呼吸运动活动。	Saunders, S. E.	PDF	N/A	Hibernation reduces GABA signaling in the brainstem to enhance motor activity of breathing at cool temperatures
表观遗传的细胞可塑性遗传性通过一对多的基因型到表型映射驱动了癌症药物的抗性。	Fernandez-Mateos, J.	PDF	N/A	Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping
TML1与TML2协同调控苜蓿根瘤形成并影响丛枝菌根共生	Chaulagain, D.	PDF	N/A	TML1 AND TML2 SYNERGISTICALLY REGULATE NODULATION AND AFFECT ARBUSCULAR MYCORRHIZA IN MEDICAGO TRUNCATULA
临床批准的BTK抑制剂对全长BTK构象的影响及慢性淋巴细胞白血病中BTK耐药突变的发展分析。	Joseph, R. E.	PDF	N/A	Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
用于从纳米孔直接RNA测序数据估计RNA修饰的原始信号分割	Cheng, G.	PDF	N/A	Raw signal segmentation for estimating RNA modification from Nanopore direct RNA sequencing data
一种新型人多能干细胞基因激活系统鉴定出IGFBP2为体外造血祖细胞生成的中介因子	Petazzi, P.	PDF	N/A	A novel human pluripotent stem cell-based gene activation system identifies IGFBP2 as a mediator in the production of hematopoietic progenitors in vitro
时间尺度与遗传连锁解释了防御系统对横向基因转移影响的可变性	Liu, Y.	PDF	N/A	Timescales and genetic linkage explain the variable impact of defense systems on horizontal gene transfer
实蝇科中的嗅觉：检测与辨别之间的平衡	Ramiaranjatovo, G.	PDF	N/A	Olfaction in Tephritidae: a balance between detection and discrimination
蛋白质组动态揭示Leiomodin 1是肌源性分化的关键调控因子	Spath, E.	PDF	N/A	Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation
Ais：简化冷冻电子断层扫描数据集的分割流程	Last, M. G. F.	PDF	N/A	Ais: streamlining segmentation of cryo-electron tomography datasets
WENDY：基于协方差动态的基因调控网络推断	Wang, Y.	PDF	N/A	WENDY: Covariance Dynamics Based Gene Regulatory Network Inference
在小鼠新皮质中，对局部创伤性脑损伤的大规模和细胞反应的成像	Bibineyshvili, Y.	PDF	N/A	Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex
通过顺式调控机制靶向三阴性乳腺癌中的昼夜节律转录程序	Pan, Y.	PDF	N/A	Targeting circadian transcriptional programs in triple negative breast cancer through a cis-regulatory mechanism
从C3向C4光合作用进化的过程是由	Yongyao, Z.	PDF	N/A	The process that the evolution from C3 towards C4 photosynthesis is driven
同源自然杀伤细胞疗法激活了转移肺中的树突状细胞和T细胞，并有效治疗了低负荷的转移病灶。	Huang, S.-W.	PDF	N/A	Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases
环境与环境之间的相互作用（ExE）在不同的遗传背景下（ExExG）有所不同。	Schmidlin, K.	PDF	N/A	Environment by environment interactions (ExE) differ across genetic backgrounds (ExExG)
Piximi - 一个用于生物图像及更广泛领域的图像发现网络工具	Moser, L. M.	PDF	N/A	Piximi - An Images to Discovery web tool for bioimages and beyond
有效的抗肿瘤免疫反应是由免疫细胞合作网络所调控的，该网络通过组织稳态通路发挥作用，而非直接的细胞毒性作用。	Koelsch, N.	PDF	N/A	Effective anti-tumor immune responses are orchestrated by immune cell partnership network that functions through tissue homeostatic pathways, not direct cytotoxicity
通过动态力学刺激增强细胞质中外源mRNA的表达	Chen, J.	PDF	N/A	Enhancing Cytoplasmic Expression of Exogenous mRNA through Dynamic Mechanical Stimulation
染色质内源性切割提供了一种对酵母RNA聚合酶II转录动力学的全局视角。	VanBelzen, J.	PDF	N/A	Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics
探索不同处理对受橄榄疫霉（Phytophthora oleae）影响的橄榄（Olea europaea L.）果实基因表达的影响：基于RNA测序的转录组分析的见解。	Conti Taguali, S.	PDF	N/A	Exploring the Impact of Various Treatments on Gene Expression in Olive (Olea europaea L.) Drupes Affected by Phytophthora oleae: Insights from RNA sequencing-based transcriptome analysis.
时间动态分析揭示，同时进行的工作记忆负荷通过破坏刺激-反应映射消除了斯特鲁普效应。	Li, Y.	PDF	N/A	Temporal dynamics analysis reveals that concurrent working memory load eliminates the Stroop effect through disrupting stimulus-response mapping
质粒病毒维持使细菌种群从感染中恢复，并实现病毒与细菌的共存。	Sanchez-Martinez, R.	PDF	N/A	Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence
预测动态控制精确绘制了2,3-丁二醇生产的设计空间	Gotsmy, M.	PDF	N/A	Predictive Dynamic Control Accurately Maps the Design Space for 2,3-Butanediol Production
SpinalTRAQ：一种新颖的颈椎脊髓体积图谱，用于识别健康和卒中后小鼠的皮质脊髓束突触投射体	Poinsatte, K.	PDF	N/A	SpinalTRAQ: A novel volumetric cervical spinal cord atlas identifies the corticospinal tract synaptic projectome in healthy and post-stroke mice
利用扩增子测序技术将微生物群落结构与功能联系起来：基于干旱胁迫下与小麦根系相关的NRPS基因的研究	Guan, Y.	PDF	N/A	Linking microbial community structure with function using amplicon sequencing of the NRPS genes associated with wheat roots under drought stress
SARS-CoV-2主蛋白酶活性位点环的构象空间由配体结合和蛋白质间别构效应决定。	Lee, E.	PDF	N/A	The Conformational Space of the SARS-CoV-2 Main Protease Active Site Loops is Determined by Ligand Binding and Interprotomer Allostery
从基因到模式：一个建模胚胎发育从转录调控中涌现的框架	Garcia-Guillen, J.	PDF	N/A	From Genes to Patterns: A Framework for Modeling the Emergence of Embryonic Development from Transcriptional Regulation
在裂殖酵母中，细胞质内的扩散随着细胞大小的增加而增加。	Tan, C.	PDF	N/A	Intracellular diffusion in the cytoplasm increases with cell size in fission yeast
慢性使用氟西汀会下调前额叶皮质中小清蛋白中间神经元的线粒体活性。	Jetsonen, E.	PDF	N/A	Chronic treatment with fluoxetine downregulates mitochondrial activity in parvalbumin interneurons of prefrontal cortex
ALG-1，一种microRNA的Argonaute蛋白，促进秀丽隐杆线虫的生殖器诱导。	Zhen, S.	PDF	N/A	ALG-1, a microRNA argonaute, promotes vulva induction in C. elegans
钾通道模拟中的电荷缩放：电导、离子占据、电压响应与选择性	Hui, C.	PDF	N/A	Charge Scaling in Potassium Channel Simulations: Conductance, Ion Occupancy, Voltage Response, and Selectivity
新型烈性噬菌体对小鼠鲍曼不动杆菌急性肺部感染的疗效与安全性	Wang, J.	PDF	N/A	Efficacy and Safety of a novel virulent phage against acute pulmonary infection of Acinetobacter baumanniii in mice
基于多组分硫内酯的可电离脂质筛选平台，用于高效且可调节的mRNA向肺部的递送	Pena, A.	PDF	N/A	Multicomponent Thiolactone-Based Ionizable Lipid Screening Platform for an Efficient and Tunable mRNA Delivery to the Lungs
18q的缺失改变了TGFβ信号传导，影响了人胚胎干细胞的前后神经外胚层命运	Lei, Y.	PDF	N/A	Loss of 18q alters TGFβ signalling affecting anteroposterior neuroectodermal fate in human embryonic stem cells
TRIM37利用肽基序识别和底物依赖性寡聚化来防止异常的纺锤体极组装。	Bellaart, A.	PDF	N/A	TRIM37 employs peptide motif recognition and substrate-dependent oligomerization to prevent ectopic spindle pole assembly
TOMM40-APOE嵌合体关联阿尔茨海默病最高风险基因：线粒体调控与APOE4发病机制的新途径	Xu, J.	PDF	N/A	TOMM40-APOE chimera linking Alzheimer's highest risk genes: a new pathway for mitochondria regulation and APOE4 pathogenesis
在果蝇癌细胞模型中，细胞集体脱层的方向性受组织结构和细胞粘附的调控。	MIRA OSUNA, M.	PDF	N/A	The directionality of collective cell delamination is governed by tissue architecture and cell adhesion in a Drosophila carcinoma model
EPHA2在食管发育过程中调控SOX2	Li, T.	PDF	N/A	EPHA2 Regulates SOX2 during Esophageal Development
失去青鳉鱼cGAS/STING功能减轻了细胞衰老和与年龄相关的特征，但并未延长生物体的寿命。	Ballhysa, E.	PDF	N/A	Loss of killifish cGAS/STING function attenuates cellular senescence and age-related signatures but does not extend organismal life span
增强型RNA靶向CRISPR-Cas技术在斑马鱼中的应用	Moreno-Sanchez, I.	PDF	N/A	Enhanced RNA-targeting CRISPR-Cas technology in zebrafish
儿童呼吸道病毒感染的局部和全身免疫反应的蛋白质组学分析	Lydon, E.	PDF	N/A	Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections
assessPool: 一个用于群体基因组分析的灵活管道，适用于合并测序数据	Freel, E. B.	PDF	N/A	assessPool: a fexible pipeline for population genomic analyses of pooled sequencing data
亚热带和热带植物物种独特的地下生态策略拓展了根系特征空间	Guerrero Ramirez, N. R.	PDF	N/A	Unique belowground ecological strategies of subtropical and tropical plant species expand the root trait space
农业集约化导致的遗传多样性丧失和遗传负荷积累的物种特异性	Nolen, Z. J.	PDF	N/A	Species-specific loss of genetic diversity and accumulation of genetic load following agricultural intensification
注射型Janus基底纳米矩阵（JBNm）在维持再生软骨长期体内平衡中的作用，适用于组织芯片应用	Yau, A.	PDF	N/A	Injectable Janus Base Nanomatrix (JBNm) in Maintaining Long-Term Homeostasis of Regenerated Cartilage for Tissue Chip Applications
使用环保溶剂增强光交联丝素蛋白的多功能性	Brooks, A. K.	PDF	N/A	Enhancing the versatility of photocrosslinkable silk fibroin using an eco-friendly solvent
人子宫组织电活动的有限元建模：模拟技术的进展	Zahran, S.	PDF	N/A	Finite Element Modeling of Electrical Activity in Human Uterine Tissue: Advances in Simulation Techniques
从非靶向代谢组学数据中直接经验性地建立药物暴露记录	Zhao, H. N.	PDF	N/A	Empirically establishing drug exposure records directly from untargeted metabolomics data
工程化年龄模拟乳腺癌模型揭示了年轻和衰老微环境中药物反应的差异	Yang, J.	PDF	N/A	Engineered Age-Mimetic Breast Cancer Models Reveal Differential Drug Responses in Young and Aged Microenvironments
利用MORFEE增强小ORF改变变异的注释：引入MORFEEdb，一个全面的人类5'UTR上游ORF受影响SNV目录	Meguerditchian, C.	PDF	N/A	Enhancing the annotation of small ORF-altering variants using MORFEE: introducing MORFEEdb, a comprehensive catalog of SNVs affecting upstream ORFs in human 5'UTRs
生物信息学分析表明，表皮葡萄球菌（Staphylococcus epidermidis）的SE_1780蛋白可能是脂肪酶Fph家族的成员。	Qaddourah, M.	PDF	N/A	Bioinformatics Analysis Suggests That SE_1780 protein from Staphylococcus epidermidis may be a member of the Fph Family of Lipases
蛋白质结构预测的终结：通过窗口化多序列比对提高嵌合蛋白质的预测准确性	Vedula, S.	PDF	N/A	The end of protein structure prediction: Improving prediction accuracy in chimeric proteins by windowed multiple sequence alignment
James-Stein估计器提高了人体运动学和代谢数据中的准确性和样本效率。	Alwan, A.	PDF	N/A	James-Stein estimator improves accuracy and sample efficiency in human kinematic and metabolic data
假单胞菌属内竞争决定了共生体在拟南芥中的保护功能	Amrhein, A.	PDF	N/A	Pseudomonas intra-genus competition determines protective function of SynComs in Arabidopsis thaliana
拟南芥莽草酸途径中的3-脱氧-D-阿拉伯糖-庚酮糖酸-7-磷酸（DAHP）合酶表现出依赖锰和钴的活性。	Yokoyama, R.	PDF	N/A	Arabidopsis 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthases of the shikimate pathway display both manganese- and cobalt-dependent activities
低强度聚焦超声神经调节揭示了丘脑在意识知觉中的作用	Jang, H.	PDF	N/A	Thalamic Roles in Conscious Perception Revealed by Low-Intensity Focused Ultrasound Neuromodulation
感知和图像记忆中的时间动态和读出延迟	Matic, K.	PDF	N/A	Temporal dynamics and readout latency in perception and iconic memory
深海鱼类揭示了脊椎动物视觉发育的替代途径	Fogg, L. G.	PDF	N/A	Deep-sea fish reveal alternative pathway for vertebrate visual development
通过细胞膜蛋白工程改造脂质体以破坏黑素小体转移	Liu, C.	PDF	N/A	Engineering liposomes with cell membrane proteins to disrupt melanosome transfer
在计算机模拟中，胶原蛋白-IV网络的非平衡重塑	Meadowcroft, B.	PDF	N/A	Non-equilibrium remodelling of collagen-IV networks in silico
硅和生物玻璃纳米材料在类髓质活体材料中的评估	Mbitta Akoa, D.	PDF	N/A	Evaluation of Silica and Bioglass Nanomaterials in Pulp-Like Living Materials
哈弗氏管内骨小梁的矿化程度取决于哈弗氏管的形成位置	Cantamessa, A.	PDF	N/A	The mineralization of osteonal cement line depends on where the osteon is formed
一种水动力天线：蝠鲼尾部的新型侧线系统	Cerda, J. C.	PDF	N/A	A hydrodynamic antenna: novel lateral line system in the tail of myliobatid stingrays
大规模饲养食用昆虫Gryllodes sigillatus（直翅目：蟋蟀科）的生长、发育及生活史	Kong, J. D.	PDF	N/A	Growth, development, and life history of a mass-reared edible insect, Gryllodes sigillatus (Orthoptera: Gryllidae)
使用SNAP标签对Munc13-1进行内源性标记，作为监测突触纳米结构的工具	Kowald, M.	PDF	N/A	Endogenous tagging of Munc13-1 with a SNAP tag as a tool for monitoring synapse nanoarchitecture
序列学习中的声音与景象：辅助听觉提示能否提升运动任务表现？	Leow, L.-A.	PDF	N/A	Sounds and Sights in Sequence Learning: Can Accessory Auditory Cues Enhance Motor Task Performance?
半胱氨酸蛋白酶抑制剂E-64的生物合成特性及组合生物催化研究	Liu, M.	PDF	N/A	Biosynthetic characterization and combinatorial biocatalysis of the cysteine protease inhibitor E-64
体外转录RNA的化学环化为环状mRNA设计开辟了新的途径	Mamot, A.	PDF	N/A	Chemical circularization of in vitro transcribed RNA opens new avenues for circular mRNA design
对选择性和双重拮抗EP2和EP4前列腺素受体的结构洞察	Wu, Y.	PDF	N/A	Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors
利用GSMMs和多组学方法改进基于HEK293的AAV生产	Zehetner, L.	PDF	N/A	Improving HEK293-based AAV-production using GSMMs, and a multi-omics approach
通过环挤出介导的刚性可以在全局范围内有序细菌染色体	Harju, J.	PDF	N/A	Loop-extruder mediated rigidity can globally order bacterial chromosomes
高吞吐量根癌农杆菌介导的植物转化半自动化工作流程	Annese, D.	PDF	N/A	Semi-automated workflow for high-throughput Agrobacterium-mediated plant transformation
球形细胞：改变硅藻DNA传递的游戏规则	Walker, E. J. L.	PDF	N/A	Spheroplasted cells: a game changer for DNA delivery to diatoms
深度突变扫描识别出能够提高II型-A CRISPR-Cas系统中间隔序列获取的Cas1和Cas2变体	Hofmann, R.	PDF	N/A	Deep mutational scanning identifies variants of Cas1 and Cas2 that increase spacer acquisition in type II-A CRISPR-Cas systems
通过冷冻电镜分析揭示的二元毒素孔道逐步成熟机制	Yamada, T.	PDF	N/A	Step-by-Step Maturation Mechanism of Binary Toxin Pore Revealed by Cryo-EM Analysis
双链DNA减少了唾液中dsRNA的降解，并显著增强了RNAi介导的Halyomorpha halys基因沉默效果。	Amineni, V. P. S.	PDF	N/A	Double-stranded DNA reduces dsRNA degradation in the saliva and significantly enhanced RNAi-mediated gene silencing in Halyomorpha halys
芒果苷作为甲状腺素纤维化潜在抑制剂的研究	Grudinina, N.	PDF	N/A	MANGIFERIN AS A POTENTIAL INHIBITOR OF TRANSTHYRETIN FIBRILOGENESIS
肿瘤抑制性miR-317和长链非编码RNA Peony源自一个多顺反子非编码RNA位点，该位点调控生殖系分化和睾丸形态。	Carney, T. D.	PDF	N/A	Tumor suppressor miR-317 and lncRNA Peony are expressed from a polycistronic non-coding RNA locus that regulates germline differentiation and testis morphology
CCG中断在DM1患者中不稳定且呈现高甲基化状态。	Lameiras, S.	PDF	N/A	CCG interruptions are unstable and hypermethylated in DM1 patients
两种人群中抗锥虫突变的新发率	Melamed, D.	PDF	N/A	De novo rates of a Trypanosoma-resistant mutation in two human populations
记者CRISPR筛选揭示了Xist位点的顺式和反式调控原理	Schwaemmle, T.	PDF	N/A	Reporter CRISPR screens decipher cis- and trans-regulatory principles at the Xist locus
鉴定拟南芥当地自然种群中存在的一种花粉杀手的相关新基因	Ricou, A.	PDF	N/A	Identification of novel genes responsible for a pollen killer present in local natural populations of Arabidopsis thaliana
CRISPR 平铺缺失筛选揭示了神经精神风险基因的功能增强子和转录的等位补偿效应（ACE）	Ren, X.	PDF	N/A	CRISPR tiling deletion screens reveal functional enhancers of neuropsychiatric risk genes and allelic compensation effects (ACE) on transcription
通过邻近条形码测序同时映射多种RNA修饰	Sendinc, E.	PDF	N/A	Mapping multiple RNA modifications simultaneously by proximity barcode sequencing
小鼠着丝粒和副着丝粒的基因组和表观基因组图谱	Chaudhry, G.	PDF	N/A	Genomic and epigenomic maps of mouse centromeres and pericentromeres
在荷兰一座城市植物园的Asparagales植物中发现了新的和变种的马铃薯Y病毒	Dekker, R. J.	PDF	N/A	Discovery of new and variant Potyviruses in Asparagales plants from a Dutch urban botanic garden
心磷脂缺乏会破坏辅酶Q的氧化还原状态并引发脂肪性肝炎	Brothwell, M. J.	PDF	N/A	Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis
通过SpyTag硫酰胺取代调节SpyCatcher连接动力学	Fiore, K.	PDF	N/A	Modulation of SpyCatcher Ligation Kinetics by SpyTag Thioamide Substitution
2.6-A分辨率的冷冻电镜结构显示了Ia类核糖核苷酸还原酶与基于机制的抑制剂N3CDP结合的复合物	Westmoreland, D. E.	PDF	N/A	2.6-A resolution cryo-EM structure of a class Ia ribonucleotide reductase trapped with mechanism-based inhibitor N3CDP
DNA聚合酶在压力下锁定复制叉	Jia, X.	PDF	N/A	DNA Polymerase Locks Replication Fork Under Stress
SIRT7与核小体结合及其底物特异性的结构基础	Moreno Yruela, C.	PDF	N/A	Structural basis of SIRT7 nucleosome engagement and substrate specificity
圆环DNA的扭转力学	Singh, G.	PDF	N/A	Torsional Mechanics of Circular DNA
Sanfetrinem是一种口服的β-内酰胺抗生素，被重新用于结核病的治疗。	Ramon-Garcia, S.	PDF	N/A	Sanfetrinem, an oral beta-lactam antibiotic repurposed for the treatment of tuberculosis
杂合和广谱的MxA超级限制因子克服了抗病毒限制中的广度特异性权衡	Geiger, R. A.	PDF	N/A	Heterozygous and generalist MxA super-restrictors overcome breadth-specificity tradeoffs in antiviral restriction
核心微生物组的系统发育测量	Bewick, S. A.	PDF	N/A	Phylogenetic Measures of the Core Microbiome
绣球属植物天然甜味剂生物合成途径的解析与功能鉴定	Padmakumar Sarala, G.	PDF	N/A	Elucidation and functional characterization of natural sweetener biosynthesis in hortensia species
寄生线虫Heligmosomoides bakeri中机会性吸血行为的证据	Szabo, E. K.	PDF	N/A	Evidence of opportunistic blood feeding in the parasitic nematode Heligmosomoides bakeri
在人类照料下的一种极度濒危的两栖动物中，精子质量指标表现出年度波动。	Julien, A. R.	PDF	N/A	Sperm quality metrics exhibit annual fluctuations in a critically endangered amphibian managed under human care
自然干扰和连通性塑造了欧洲水生大型无脊椎动物群落季节性变化的格局	Chalmandrier, L.	PDF	N/A	Natural disturbances and connectivity shape the seasonal variability of aquatic macroinvertebrate communities across Europe
# BioRxiv 2024-10-08 Papers

标题	作者	PDF链接	代码仓库	Title
BEdeepon：一种用于预测碱基编辑效率和结果的计算机工具	Zhang, C.	PDF	N/A	BEdeepon: an in silico tool for prediction of base editor efficiencies and outcomes
受生物物理启发的神经元群体平均场模型，由离子交换机制驱动	Rabuffo, G.	PDF	N/A	Biophysically inspired mean-field model of neuronal populations driven by ion exchange mechanisms
从初始形成到发展性精炼：GABA能输入塑造初级体感皮层中的神经元子网络	Huang, J.-Y.	PDF	N/A	From Initial Formation to Developmental Refinement: GABAergic Inputs Shape Neuronal Subnetworks in the Primary Somatosensory Cortex
对蓝钟虫前后mRNA区域化的全基因组分析揭示了微管细胞骨架的作用	Albright, A. R.	PDF	N/A	Genome-wide analysis of anterior-posterior mRNA regionalization in Stentor coeruleus reveals a role for the microtubule cytoskeleton
采用理性方法对抗体序列进行预训练	Gao, X.	PDF	N/A	Pre-training with a rational approach for antibody sequence representation
同一感知决策任务的多种脑激活模式	Nakuci, J.	PDF	N/A	Multiple Brain Activation Patterns for the Same Perceptual Decision-Making Task
饱腹激素胆囊收缩素通过调控促性腺激素分泌，在鱼类中调控生殖过程。	Hollander cohen, L.	PDF	N/A	The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion
新的纯化方法揭示酵母和人类应激颗粒核心是具有复杂转录组和蛋白质组的离散颗粒	Demeshkina, N. A.	PDF	N/A	New purifications reveal yeast and human stress granule cores are discrete particles with complex transcriptomes and proteomes
人类ADA2缺乏症的特点是缺乏细胞内低糖基化的腺苷脱氨酶2形式。	Ehlers, L.	PDF	N/A	Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2
通过干扰主调控bHLH异二聚体，利用ACT样域进行化学抑制气孔分化	Nakagawa, A.	PDF	N/A	Chemical inhibition of stomatal differentiation by perturbation of the master-regulatory bHLH heterodimer via an ACT-Like domain
新型神经启发式控制器通过内部模型在低级肢体任务中实现了模块化泛化	Munoz, D.	PDF	N/A	New neural-inspired controller generalises modularity over lower limb tasks through internal models
酵母中的单细胞eQTL定位揭示了生长与繁殖之间的权衡	Boocock, J.	PDF	N/A	Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction
质膜孔作为非传统的膜接触位点，在植物细胞间的分子交换中起着调节作用。	Smokvarska, M.	PDF	N/A	Plasmodesmata act as unconventional membrane contact sites regulating inter-cellular molecular exchange in plants
评估大型多模态模型在生物医学图像分类中的一步学习能力和可解释性	Hou, W.	PDF	N/A	Assessing large multimodal models for one-shot learning and interpretability in biomedical image classification
神经发育障碍相关TRIO变异的杂合性在行为、神经发育和突触传递方面导致小鼠出现不同的缺陷。	Ishchenko, Y.	PDF	N/A	Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice
预期情绪与学业表现：在实习教师实验室体验中无聊的作用	Ochoa de Alda, J. A. G.	PDF	N/A	Anticipatory Emotions and Academic Performance: The Role of Boredom in a Preservice Teachers' Lab Experience
小鼠树突靶向中间神经元中的超线性树突整合	Griesius, S.	PDF	N/A	Supralinear dendritic integration in murine dendrite-targeting interneurons
基于高维数据的生态学与进化可解释性和预测性模型	Jahner, J. P.	PDF	N/A	Interpretable and predictive models based on high-dimensional data in ecology and evolution
神经元中Ptbp1的碱基编辑减轻了帕金森病小鼠模型的症状	Boeck, D.	PDF	N/A	Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model for Parkinson's disease
释放Krakencoder：一种统一的脑连接组翻译和融合工具	Jamison, K. W.	PDF	N/A	Release the Krakencoder: A unified brain connectome translation and fusion tool
单细胞中核糖体含量的异质性及其对生长规律的影响	Brettner, L. M.	PDF	N/A	Single-cell heterogeneity in ribosome content and the consequences for the growth laws
评估泛基因组图谱上的基因组保守性——基于PanSel的方法	Zytnicki, M.	PDF	N/A	Assessing genome conservation on pangenome graphs with PanSel
对短语结构和主语岛违例敏感的皮层网络	Matchin, W.	PDF	N/A	Cortical networks responsive to phrase structure and subject island violations
利用光遗传学工具在Neuro2a细胞中诱导应激颗粒和稳定的tau聚集。	Sakuragi, S.	PDF	N/A	Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool.
预测持续注意力的功能脑网络并不特定于感知模态	Corriveau, A.	PDF	N/A	Functional brain networks predicting sustained attention are not specific to perceptual modality
CLEAN-Contact：基于对比学习的酶功能注释预测与结构推断	Yang, Y.	PDF	N/A	CLEAN-Contact: Contrastive Learning-enabled Enzyme Functional Annotation Prediction with Structural Inference
将心磷脂结合到人工膜蛋白上揭示了脂质介导稳定性的决定因素	Abramsson, M. L.	PDF	N/A	Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization
外部微生物群通过卵壳与正在发育的斑马鱼（Danio rerio）胚胎进行交流，并影响其发育轨迹。	Green, E. M.	PDF	N/A	The External Microbiome Communicates with the Developing Zebrafish (Danio rerio) Embryo Through the Chorion and Influences Developmental Trajectory
齿状回中功能失调的S1P/S1PR1信号传导驱动了慢性疼痛相关记忆障碍的易感性	Cui, M.	PDF	N/A	Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
BIT：基于表观基因组学查询区域集的转录调控因子贝叶斯识别	Lu, Z.	PDF	N/A	BIT: Bayesian Identification of Transcriptional Regulators from Epigenomics-Based Query Region Sets
揭示亲炎性巨噬细胞在子痫前期母胎界面免疫网络失衡中的关键作用	Fei, H.	PDF	N/A	Unveiling the Crucial Role of Pro-inflammatory Macrophages in the Immune Network Imbalance of the maternal-fetal interface with Preeclampsia
单细胞和空间转录组学分析揭示了心肌梗死后心肌淋巴管生成的动态转录特征	He, J.	PDF	N/A	Single-Cell and Spatial Transcriptomic Analyses Reveals the Dynamic Transcript Profiles of Myocardial Lymphangiogenesis post Myocardial Infarction
听觉皮层中协同调谐的神经元集合活动的快速再平衡	Kang, H.	PDF	N/A	Rapid rebalancing of co-tuned ensemble activity in the auditory cortex
scCancerExplorer：一个综合数据库，用于交互式探索人类泛癌单细胞多组学数据	Huang, C.	PDF	N/A	scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer
巨型转座子促进主要真菌病原体中的菌株异质性	Gluck-Thaler, E.	PDF	N/A	Giant transposons promote strain heterogeneity in a major fungal pathogen
基于注意力的前额-后部耦合在人类大脑视觉意识中的作用	Zhang, X.	PDF	N/A	Attention-based frontal-posterior coupling for visual consciousness in the human brain
一个双组分信号决定了哪些锈菌分泌的蛋白质被转运到寄主植物的细胞中。	Lawrence, G. J.	PDF	N/A	A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant
超越听觉中继：剖析下丘在感觉预测、奖励预测及认知决策中的作用	Du, X.	PDF	N/A	Beyond Auditory Relay: Dissecting the Inferior Colliculus's Role in Sensory Prediction, Reward Prediction and Cognitive Decision-Making
降落在摇摆的栖木上：桃脸情侣鹦鹉偏爱极端	Bhagavatula, P. S.	PDF	N/A	Landing on a swinging perch: peach-faced lovebirds prefer extremes
利用磷酸蛋白质组学解析卵母细胞减数分裂过程中的蛋白质磷酸化	Peshkin, L.	PDF	N/A	Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics
通过血清素受体协同调节自发行为和时间积分全脑神经元活动	Friedmann, D.	PDF	N/A	Concerted modulation of spontaneous behavior and time-integrated whole-brain neuronal activity by serotonin receptors
刺激编码塑造了触觉感知，并构成了自闭症中触觉感知的改变的基础。	Semelidou, O.	PDF	N/A	Stimulus encoding shapes tactile perception and underlies alterations in autism.
与番茄黄曲叶病相关的菜豆金色花叶病毒在西地中海国家的人口变化	Granier, M.	PDF	N/A	Population shifts in begomoviruses associated with tomato yellow leaf curl disease in western Mediterranean countries
SAFARI：利用嘌呤/嘧啶编码进行古DNA的泛基因组比对	Rubin, J. D.	PDF	N/A	SAFARI: Pangenome Alignment of Ancient DNA Using Purine/Pyrimidine Encodings
较低的非周期性活动与成年期言语流利性表现下降相关	McKeown, D. J.	PDF	N/A	Lower Aperiodic Activity is Associated with Reduced Verbal Fluency Performance Across Adulthood
蓝细菌氮调节因子NtcA和PipX与DNA复合物的结构完全阐明了NtcA对DNA的结合以及PipX对RNA聚合酶的招募机制。	Forcada-Nadal, A.	PDF	N/A	Structures of the cyanobacterial nitrogen regulators NtcA and PipX complexed to DNA fully clarify DNA binding by NtcA and recruitment of RNA polymerase by PipX
运动感知阿尔法和贝塔振荡在显性言语产生中的功能角色	Huang, L. Z.	PDF	N/A	Functional Roles of Sensorimotor Alpha and Beta Oscillations in Overt Speech Production
HHIP在表皮伤口愈合中的动态作用揭示了COPD易感性的潜在机制	Deritei, D.	PDF	N/A	HHIP's Dynamic Role in Epithelial Wound Healing Reveals a Potential Mechanism of COPD Susceptibility
从视觉皮层活动动态估计注意场	Bloem, I. M.	PDF	N/A	Dynamic estimation of the attentional field from visual cortical activity
辅助嗅球中的突触抑制调节信息素定位学习和记忆	Marathe, S. D.	PDF	N/A	Synaptic inhibition in the accessory olfactory bulb regulates pheromone location learning and memory
一个涵盖5000年历史的考古牙结石数据集，用于古代人类口腔微生物组研究	Standeven, F. J.	PDF	N/A	An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research
从头组装自私t超级基因揭示了有害的进化轨迹	Runge, J.-N.	PDF	N/A	De novo assembly of the selfish t supergene reveals a deleterious evolutionary trajectory
撤回：新型神经启发式控制器通过内部模型在低肢任务中推广了模块化	Munoz, D.	PDF	N/A	WITHDRAWN: New neural-inspired controller generalises modularity over lower limb tasks through internal models
分支肌动蛋白聚合推动侵入性突起的形成，以促进骨骼肌再生过程中肌纤维融合。	Lu, Y.	PDF	N/A	Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration
长角甲虫利用磷酸钙生物矿物形成结构色	Chang, Y.	PDF	N/A	Longhorn Beetles form Structural Colour Using Calcium Phosphate Biominerals
临床和分子变异特性对变异效应预测工具校准和性能的影响	Isakov, O.	PDF	N/A	The Impact of Clinical and Molecular Variant Properties on Calibration and Performance of Variant Effect Prediction Tools
更多的细胞，高度多重单细胞数据中的更多双联体	Howitt, G.	PDF	N/A	More cells, more doublets in highly multiplexed single-cell data
通过使用大肠杆菌作为模型微生物，区分纳米铜和离子铜的抗菌机制	Jose, G. P.	PDF	N/A	Differentiating the mechanism of antibacterial activities of nano and ionic copper by using Escherichia coli as a model microorganism
ADT-1004：一种口服生物可利用的选择性泛RAS抑制剂，用于胰腺导管腺癌	Bandi, D. S. R.	PDF	N/A	ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma
TGF-β介导的JunB-HBZ核转位是HTLV-1诱导白血病的关键驱动因素	Zhang, W.	PDF	N/A	JunB-HBZ nuclear translocation by TGF-β is a key driver in HTLV-1-mediated leukemogenesis
计算设计一种用于全细胞生物转化的热稳定从头生物催化剂	Elaily, W.	PDF	N/A	Computational design of a thermostable de novo biocatalyst for whole cell biotransformations
计算设计一种用于全细胞生物转化的热稳定从头生物催化剂	Elaily, W.	PDF	N/A	Computational design of a thermostable de novo biocatalyst for whole cell biotransformations
在无序环境中范围扩展的元种群模型中的几何诱导竞争释放	Nunez, J. G.	PDF	N/A	Geometry-induced competitive release in a meta-population model of range expansions in disordered environments
基因组报告：首次完成吸血猎蝽（Triatoma sanguisuga，Le Conte, 1855）的全基因组测序，该物种是恰加斯病的传播媒介	Peterson, J. K.	PDF	N/A	Genome report: First whole genome sequence of Triatoma sanguisuga (Le Conte, 1855), vector of Chagas disease
厩螫蝇（双翅目，家蝇科）是多种家畜血液病原体的有效传播媒介。	Muita, J. W.	PDF	N/A	Stomoxys flies (Diptera, Muscidae) are competent vectors of multiple livestock hemopathogens
植物基因型和微生物菌株组合对重金属胁迫条件下的转录组有显著影响	Sharma, R.	PDF	N/A	Plant genotype and microbial strain combinations strongly influence the transcriptome under heavy metal stress conditions
预测西非关键生物多样性区域近期森林砍伐情况，以指导保护紧迫性	Trew, B. T.	PDF	N/A	Predicting near-future deforestation in West African Key Biodiversity Areas to inform conservation urgency
免疫-病原体共进化中的信息处理自适应效率	Bellamy, Q. N.	PDF	N/A	Adaptive efficiency of information processing in immune-pathogen co-evolution
海洋群岛进化辐射的生物地理学	Baptiste, B.	PDF	N/A	The biogeography of evolutionary radiations on oceanic archipelagos
一种综合的全基因组方法，用于探索魏斯氏菌的益生潜力	Hashem, A.	PDF	N/A	A Comprehensive Pangenome Approach to Exploring the Probiotic Potential of Weissella Confusa
苗圃和园艺中心作为外来植物入侵的中心	Sonkoly, J.	PDF	N/A	Nurseries and garden centres as hubs of alien plant invasions
在高pH胁迫下豌豆根部的转录响应与微生物群落变化	Thapa, A.	PDF	N/A	Transcriptional Responses and Microbiome Shifts in Pea Roots Under High pH Stress
核纤层蛋白A的心肌病突变扰乱了核纤层蛋白、核膜和染色质之间的相互作用，导致低液相分离（LLPS）。	Nath, S.	PDF	N/A	Cardiomyopathic mutations of lamin A perturb mutual interactions of lamin, nuclear membrane, and chromatin leading to LLPS
评估几内亚比绍极度濒危的西部黑猩猩在时空上的有效种群大小：对保护管理的挑战与影响	Ferreira da Silva, M. J.	PDF	N/A	Estimating the effective population size across space and time in the Critically Endangered western chimpanzee in Guinea-Bissau: challenges and implications for conservation management
基于压缩和k-mer的抗癌肽分析方法	Ali, S.	PDF	N/A	Compression and k-mer based Approach For Anticancer Peptide Analysis
基于压缩和k-mer的抗癌肽分析方法	Ali, S.	PDF	N/A	Compression and k-mer based Approach For Anticancer Peptide Analysis
早期生活行为表型与慈鲷鱼对常见实验室应激源的皮质醇反应	Alvey, A. P.	PDF	N/A	Early Life Behavior Phenotypes and Cortisol Responses to Common Lab Stressors in a Cichlid Fish
人工智能对生物医学文献搜索的贡献：是革命性的还是复杂化的？	Yip, R.	PDF	N/A	Artificial Intelligence's Contribution to Biomedical Literature Search: Revolutionizing or Complicating?
表达胆囊收缩素（Cholecystokinin）的GABA神经元在皮层抑制性突触中引发长期增强效应，并减弱声音-电击关联记忆。	Zhang, G.	PDF	N/A	Cholecystokinin-expressing GABA neurons elicit long-term potentiation in the cortical inhibitory synapses and attenuate sound-shock associative memory
任务相关性在存在多个预测误差的情况下有选择性地调节感觉运动适应。	Shingane, S. N.	PDF	N/A	Task relevance selectively modulates sensorimotor adaptation in the presence of multiple prediction errors.
用于共聚焦显微镜单个致密核心囊泡可视化的基因编码标记	Yu, J.	PDF	N/A	Genetically-encoded markers for confocal visualization of single dense core vesicles
利用患者特异性iPSCs建模胸主动脉夹层揭示了血管平滑肌细胞功能障碍及细胞外基质失调	Jin, P.	PDF	N/A	Modeling Thoracic Aortic Dissection Using Patient-Specific iPSCs Reveals VSMC Dysfunction and Extracellular Matrix Dysregulation
建模丙泊酚对脑活动的影响：来自计算脑电图研究的见解	Zahran, S.	PDF	N/A	Modeling the Effects of Propofol on Brain Activity: Insights from Computational EEG Studies
自我扩增mRNA疫苗编码蛋白在肌肉和淋巴结中的差异清除率	Kanechi, R.	PDF	N/A	Differential clearance rate of proteins encoded on a self-amplifying mRNA vaccine in muscle and lymph nodes
在热带木本豆科植物的根瘤中鉴定出的小热休克蛋白（sHSPs）。	Flynn, C.	PDF	N/A	Small heat shock proteins (sHSPs) identified in nodules of tropical woody legumes.
小细胞肺癌的转移器官倾向性	Krishnamurthy, M.	PDF	N/A	Metastatic organotropism in small cell lung cancer
一种自主微生物传感器能够长期检测自然土壤中的TNT炸药	Essington, E. A.	PDF	N/A	An Autonomous Microbial Sensor Enables Long-term Detection of TNT Explosive in Natural Soil
一个强大的合成生物学工具包，用于推进羧酶体研究和设计	Trettel, D.	PDF	N/A	A robust synthetic biology toolkit to advance carboxysome study and design
两种温度响应RNA协同作用：小RNA CyaR和mRNA ompX	Guanzon, D. A.	PDF	N/A	Two temperature-responsive RNAs act in concert: The small RNA CyaR and the mRNA ompX
DNA/多核糖体相分离与细胞宽度限制共同作用，将核区分离与大肠杆菌细胞生长耦合	Papagiannakis, A.	PDF	N/A	DNA/polysome phase separation and cell width confinement couple nucleoid segregation to cell growth in Escherichia coli
MreC-MreD结构揭示了一个多方面的界面，该界面控制着MreC的构象。	Gilman, M. S. A.	PDF	N/A	MreC-MreD structure reveals a multifaceted interface that controls MreC conformation
异养硝化作用关键酶——丙酮酸肟双加氧酶的结构表征	Tsujino, S.	PDF	N/A	Structural characterization of pyruvic oxime dioxygenase, a key enzyme of heterotrophic nitrification
解读未被开发的古菌域中RiPPs的化学景观及其潜在生态功能	Zhiman, S.	PDF	N/A	Deciphering the chemical landscape and potential ecological function of RiPPs from the untapped Archaea domain
环境和饮食塑造了特定地理区域的果蝇黑腹菌群组成。	Gale, J. T.	PDF	N/A	Environment and diet shape the geography-specific Drosophila melanogaster microbiota composition
通过一种超快速生物过程减轻一氧化二氮排放，实现高浓度N2O的去除	Maeda, R.	PDF	N/A	Mitigating nitrous oxide emission by an ultra-fast bioprocess enabling the removal of high concentration N2O
硫醇应激促进吡嗪酰胺对抗结核分枝杆菌的作用	Ostrer, L.	PDF	N/A	Thiol Stress Fuels Pyrazinamide Action Against Mycobacterium tuberculosis
MMV大流行响应盒的功能表型分析鉴定出针对疟原虫血液期的阶段特异性抑制剂	Chandramohanadas, R.	PDF	N/A	Functional Phenotyping of MMV Pandemic Response Box Identifies Stage-specific inhibitors Against Blood stage Plasmodium
大肠杆菌的复制起始蛋白DnaA在染色体上被滴定。	Olivi, L.	PDF	N/A	The Escherichia coli replication initiator DnaA is titrated on the chromosome
AAV Rep中同义突变的增强基因组包装在文库筛选中的作用	Azim, T.	PDF	N/A	Synonymous mutations in AAV Rep enhance genome packaging in a library selection
使用商业血浆富集策略增强的人脑脊液蛋白质组分析	Borras, E.	PDF	N/A	Enhanced proteome profiling of human cerebrospinal fluid using a commercial plasma enrichment strategy
Vault RNAs通过促进hnRNP C和ELAVL1的核外排，助力病毒感染。	Stok, J. E.	PDF	N/A	Vault RNAs aid viral infection by facilitating nuclear export of hnRNP C and ELAVL1
对暴露于农药的克氏原螯虾（Procambarus clarkii）进行转录组和生化分析：种群特异性反应作为污染物抗性的标志？	Martinez-Alarcon, D.	PDF	N/A	Transcriptomic and Biochemical analysis of Procambarus clarkii upon exposure to Pesticides: Population-Specific responses as a sign of pollutant resistance?
整合近端泛素组学分析用于去泛素酶和E3连接酶底物发现：以USP30为例	Damianou, A.	PDF	N/A	Integrative Proximal-Ubiquitomics Profiling for Deubiquitinase and E3 Ligase Substrate Discovery Applied to USP30
重新审视雄蚊的非吸血模式	Bozic, J.	PDF	N/A	Revisiting the paradigm of anhematophagy in male mosquitoes
可扩展的从猪气管中提取气道粘蛋白的方法	Yang, S.	PDF	N/A	Scalable Extraction of Airway Mucins from Porcine Trachea
一种用于基因调控的丝状支架	Rasmussen, T.	PDF	N/A	A filamentous scaffold for gene regulation
钙调蛋白对CHK2激酶的非常规结合抑制了其催化活性	Horne, C. R.	PDF	N/A	Unconventional binding of Calmodulin to CHK2 kinase inhibits catalytic activity
通过核心变构结构网络调节IL-2免疫信号功能	Woodward, C. H.	PDF	N/A	Regulating IL-2 immune signaling function via a core allosteric structural network
使用SIREn对冷冻电镜体积集合进行自动化无模型分析	Kinman, L. F.	PDF	N/A	Automated model-free analysis of cryo-EM volume ensembles with SIREn
乳酸的直接线粒体导入支持了碳水化合物的弹性氧化	Cluntun, A. A.	PDF	N/A	Direct mitochondrial import of lactate supports resilient carbohydrate oxidation
整合N-糖基化和CODEX成像揭示健康人肺细胞特异性蛋白质糖基化	Velickovic, D.	PDF	N/A	Integrating N-glycan and CODEX imaging reveal cell-specific protein glycosylation in healthy human lung
利用HILIC/ERLIC分离技术进行RNA聚合酶II C端结构域磷酸肽异构体的在线纳米级LC-MS/MS分析	Ficarro, S. A.	PDF	N/A	Leveraging HILIC/ERLIC Separations for Online Nanoscale LC- MS/MS Analysis of Phosphopeptide Isoforms from RNA Polymerase II C-terminal Domain
对Pseudomonas putida KT2440 Omega转氨酶结构洞察与合理设计以增强(R)-苯乙酰甲醇至(1R, 2S)-去甲麻黄碱的生物转化	Das, P.	PDF	N/A	Structural insights and rational design of Pseudomonas putida KT2440 Omega transaminases for enhanced biotransformation of (R)-Phenylacetylcarbinol to (1R, 2S)-Norephedrine
在310K下，对微摩尔浓度的α-突触核蛋白和tau蛋白进行细胞内残基分辨的核磁共振分析	Cherot, H.	PDF	N/A	In-cell residue-resolved NMR of micromolar α-synuclein and tau at 310K
通过pH缓冲增强酶活性：生物分子凝聚体的贡献	Stoffel, F.	PDF	N/A	Enhancement of Enzymatic Activity by Biomolecular Condensates through pH Buffering
DoriVac（DNA折纸疫苗）在转移性黑色素瘤模型中的疗效验证	Rajwar, A.	PDF	N/A	Validation of DoriVac (DNA origami vaccine) efficacy in a metastatic melanoma model
伪缺氧稳定化的HIF2α转录抑制MNRR1，MNRR1是MELAS中一个可药物化的靶点	Purandare, N.	PDF	N/A	Pseudohypoxia-stabilized HIF2α transcriptionally inhibits MNRR1, a druggable target in MELAS
# BioRxiv 2024-10-07 Papers

标题	作者	PDF链接	代码仓库	Title
关于已知最早生命形式的本质	Kanaparthi, D.	PDF	N/A	On the nature of the earliest known life forms
肠道细菌衍生的鞘脂类物质改变了对口服霍乱疫苗抗原的先天免疫反应	Chac, D.	PDF	N/A	Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens
可扩展的基于图像的空间转录组数据集可视化与对齐	Preibisch, S.	PDF	N/A	Scalable image-based visualization and alignment of spatial transcriptomics datasets
PERK激酶活性受铜结合调控——调节内质网应激耐受的新型调控范式	Newton, S. E. B.	PDF	N/A	PERK Kinase Activity is Regulated by Copper Binding-A New Regulatory Paradigm for Modulation of ER Stress Tolerance
核苷酸变压器：构建和评估人类基因组学的稳健基础模型	Dalla-Torre, H.	PDF	N/A	The Nucleotide Transformer: Building and Evaluating Robust Foundation Models for Human Genomics
单荧光团成像揭示了生物分子凝聚体的不同环境和结构特征	Wu, T.	PDF	N/A	Single fluorogen imaging reveals distinct environmental and structural features of biomolecular condensates
双重MAPK抑制触发促炎信号并增强BRAF V600E胶质瘤对T细胞介导的检查点疗法的敏感性	Xing, Y. L.	PDF	N/A	Dual MAPK Inhibition Triggers Pro-inflammatory Signals and Sensitizes BRAF V600E Glioma to T Cell-Mediated Checkpoint Therapy
稳态突触缩放与稳态结构可塑性之间的相互作用维持了神经网络的稳健放电率。	Lu, H.	PDF	N/A	The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks
通过从整体到单细胞的解卷积方法，描绘白血病干细胞的药物敏感性	Alexandre, C.	PDF	N/A	Profiling drug sensitivity of leukemic stem cells via bulk-to-single-cell deconvolution
在工作记忆中，视觉层次结构逐渐向类别表征过渡，但在感知过程中并非如此。	Chunharas, C.	PDF	N/A	A gradual transition toward categorical representations along the visual hierarchy during working memory, but not perception.
一种新型泛RAS抑制剂，其独特的作用机制可阻断小鼠模型中胃肠癌的生长	Foote, J.	PDF	N/A	A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer
使用传递熵测量评估RAS-MAPK系统中的信息流	Umeki, N.	PDF	N/A	Evaluation of information flows in the RAS-MAPK system using transfer entropy measurements
稳定性指标在不同数据质量下表现稳健，但对社区规模较为敏感。	O'Brien, D. A.	PDF	N/A	Stability metrics are robust across data qualities but sensitive to community size.
RpoS激活了沙门氏菌Typhi生物膜的形成，并驱动其在胆囊中的持久性。	Desai, S.	PDF	N/A	RpoS activates formation of Salmonella Typhi biofilms and drives persistence in the gall bladder
进化相关性对物种多样化和树形的影响	Qin, T.	PDF	N/A	Impact of Evolutionary Relatedness on Species Diversification and Tree Shape
古多肽中的电子自旋极化与电荷动力学：它们在蛋白质功能中的作用	Vyas, P.	PDF	N/A	Electron Spin-Polarizability and Charge Dynamics in Ancient Polypeptides : Their Role in Protein Function
皮质连接组的高阶结构中的特定抑制和去抑制	Reimann, M. W.	PDF	N/A	Specific inhibition and disinhibition in the higher-order structure of a cortical connectome
使用因果启发的神经网络进行治疗扰动的组合预测	Gonzalez, G.	PDF	N/A	Combinatorial prediction of therapeutic perturbations using causally-inspired neural networks
通过从相同原始读取数据中提取的保守核基因序列和整个叶绿体基因组，对亚科进化进行了综合研究。	Witharana, E. P.	PDF	N/A	Comprehensive study of subfamily evolution through sequences of conserved nuclear genes and whole chloroplast genomes extracted from the same raw read data
过量磷酸盐对沿海浮游生物群落的影响：波罗的海中尺度实验	Spilling, K.	PDF	N/A	Effects of excess phosphate on a coastal plankton community: a mesocosm experiment in the Baltic Sea
一种结核分枝杆菌分泌的毒力因子破坏宿主snRNP生物发生	Chauhan, K.	PDF	N/A	A Mycobacterium tuberculosis secreted virulence factor disrupts host snRNP biogenesis
探索在不同热带森林、树木组织和发育阶段中的茜草科真菌内生菌	Castillo-Gonzalez, H.	PDF	N/A	Exploring Rubiaceae fungal endophytes across contrasting tropical forests, tree tissues, and developmental stages
在寄生蜂Lysiphlebus fabarum中，兼性性别是否是两全其美的选择？	Boulton, R. A.	PDF	N/A	Is facultative sex is the best of both worlds in the parasitoid wasp Lysiphlebus fabarum?
动态强化学习揭示了奖励学习过程中策略随时间变化的转变。	Venditto, S. J. C.	PDF	N/A	Dynamic reinforcement learning reveals time-dependent shifts in strategy during reward learning.
范德华力、静电作用和氢键在纤维素Iβ和II晶体相对稳定性中的作用	Kullmann, R.	PDF	N/A	Role of van der Waals, electrostatic, and hydrogen-bond interactions for the relative stability of cellulose Iβ and II crystals
人CTF18夹钳加载器与PCNA结合的结构	Briola, G.	PDF	N/A	Structure of the human CTF18 clamp loader bound to PCNA
使用Sentence-BERT从预测数据库中提炼疾病中的蛋白质水平微RNA靶标相互作用	Chen, B.	PDF	N/A	Refining Protein-Level MicroRNA Target Interactions in Disease from Prediction Databases Using Sentence-BERT
GTP环水解酶II（gch2）与球蟒中的色觉缺失：基于蝶呤色素沉着的新脊椎动物模型	Garcia-Elfring, A.	PDF	N/A	GTP cyclohydrolase II (gch2) and axanthism in ball pythons: a new vertebrate model for pterin-based pigmentation
激活血红素代谢促进关节内损伤或手术暴露后的组织健康	Liman, S.	PDF	N/A	Activation of Heme Metabolism Promotes Tissue Health after Intraarticular Injury or Surgical Exposure
NMDARs和协同激动剂的位置控制着黑质多巴胺神经元中爆发的产生	Ringlet, S.	PDF	N/A	Location of NMDARs and co-agonist controls the generation of bursts in nigral dopamine neurons
II型糖尿病中骨骼肌肌球蛋白超松弛与能量代谢失调	Lewis, C. T.	PDF	N/A	Dysregulated Skeletal Muscle Myosin Super-relaxation and Energetics in Type II Diabetes
HIV共受体相关基因（CCR5和CXCR4）启动子甲基化：原创研究	Esman, A.	PDF	N/A	HIV Coreceptors Related Genes (CCR5 and CXCR4) Promoter Methylation: Original Research
MatP在细菌细胞分裂周期时空调控中的生物分子凝聚体的证据	Barros-Medina, I.	PDF	N/A	Evidence for biomolecular condensates of MatP in spatiotemporal regulation of the bacterial cell division cycle
MLCK/MLCP通过重新分布生长锥的F-肌动蛋白来调节哺乳动物轴突的再生	Saijilafu,	PDF	N/A	MLCK/MLCP regulates mammalian axon regeneration via the redistribution of the growth cone F-actin
大肠杆菌细胞中DnaA和DNA的相对分布作为其表型变异的因素	Namboodiri, S. K.	PDF	N/A	Relative Distribution of DnaA and DNA in Escherichia coli Cells as a Factor of Their Phenotypic Variability
克服冷冻电镜图各向异性揭示了具有不同化学计量比的ALK-细胞因子复合物	Felix, J.	PDF	N/A	Overcoming cryo-EM map anisotropy reveals ALK-cytokine assemblies with distinct stoichiometries
外毛细胞搅动耳蜗内的液体	Lee, C.	PDF	N/A	Outer hair cells stir cochlear fluids
多巴胺与时间折扣：重新审视药理学与个体差异	Smith, E.	PDF	N/A	Dopamine and temporal discounting: revisiting pharmacology and individual differences
IL-6和IL-27负向调控与淋巴驱动性滑膜炎相关的CRTAM表达CD4+ T细胞。	Derrac Soria, A.	PDF	N/A	IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.
分布式学习推动了统计抑制和聋化	Luthra, S.	PDF	N/A	Distributional learning drives statistical suppression and deafening
一种受生理启发的混合CPG/反射控制器，用于自行车模拟，并可推广到步行	Severini, G.	PDF	N/A	A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking
一个小的信号域控制着磷酸肌醇磷酸酶5激酶（PPIP5K）在磷酸盐稳态中的磷酸酶活性。	Raia, P.	PDF	N/A	A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis.
一种基于纳米抗体的方法，用于在活细胞中捕获和可视化二元蛋白质复合物的特定相互作用	Sleiman, N. H.	PDF	N/A	A nanobody-based approach to capture and visualize specific interactions of binary protein complexes in living cells
利用MELISSA模型对整合位点数据进行安全评估	Lin, T.-Y.	PDF	N/A	Modeling integration site data for safety assessment with MELISSA
全球土壤传播蠕虫的多样性揭示了影响诊断目标的群体偏向性遗传变异	Papaiakovou, M.	PDF	N/A	Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets
一个支持法国淡水环境中水生大型无脊椎动物DNA条形码分析的注释参考库	Gauvin, P.	PDF	N/A	An annotated reference library for supporting DNA metabarcoding analysis of aquatic macroinvertebrates in French freshwater environments
斑马鱼Pol-Theta与人Pol-Theta，具有同源功能的直系同源物	Thomas, C.	PDF	N/A	Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function
微流控技术调控显微切割肿瘤中的微血管	Nguyen, T. N. H.	PDF	N/A	Microfluidic Modulation of Microvasculature in Microdissected Tumors
H3K9甲基化非依赖性活性在异染色质焦点、基因抑制和器官发生中的HPL-2/HP1作用	Delaney, C. E.	PDF	N/A	H3K9 methylation-independent activity for HPL-2/HP1 in heterochromatin foci, gene repression, and organogenesis
IgBlend：在抗体语言模型中统一三维结构和序列	Malherbe, C.	PDF	N/A	IgBlend: Unifying 3D Structures and Sequences in Antibody Language Models
茄科生物合成基因簇的亚功能化与表观遗传调控	Priego-Cubero, S.	PDF	N/A	Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae
具有改变的RNA结合和降解活性的病理性PNPase变体影响细菌和人类细胞模型的表型	Pizzoccheri, R.	PDF	N/A	Pathological PNPase variants with altered RNA binding and degradation activity affect the phenotype of bacterial and human cell models
普遍规则支配着质粒拷贝数	Ramiro-Martinez, P.	PDF	N/A	Universal rules govern plasmid copy number
一种以基因型为先导的方法在狗中识别出与口腔面部裂和其他表型相关的变异	Buckley, R. M.	PDF	N/A	A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs
利用多组儿科临床睡眠数据洞察神经发育：儿科睡眠回顾性分析（RASP）队列研究	Gong, N. N.	PDF	N/A	Leveraging clinical sleep data across multiple pediatric cohorts for insights into neurodevelopment: the Retrospective Analysis of Sleep in Pediatric (RASP) cohorts study
早期听觉和成年求偶经历与歌者身份相互作用，塑造雌性斑胸草雀对歌声的神经反应	Catalano, I.	PDF	N/A	Early auditory and adult mating experiences interact with singer identity to shape neural responses to song in female zebra finches
悬浮组织开放式微流控图案化技术（STOMP）	Haack, A. J.	PDF	N/A	Suspended Tissue Open Microfluidic Patterning (STOMP)
TSST-1通过激活CD8+T细胞促进金黄色葡萄球菌在阴道内的定植	Dufresne, K.	PDF	N/A	TSST-1 promotes colonization of Staphylococcus aureus within the vaginal tract by activation of CD8+T cells
青少年在晶体智力和流体智力方面的神经相关性存在差异	Qiu, B.	PDF	N/A	Neural correlates differ between crystallized and fluid intelligence in adolescents
顶枕叶伽马经颅交流电刺激对视觉空间注意任务中行为表现和神经活动的影响	Zheng, T.	PDF	N/A	After-effects of Parieto-occipital Gamma Transcranial Alternating Current Stimulation on Behavioral Performance and Neural Activity in Visuo-spatial Attention Task
亨廷顿病小鼠模型中运动学习和皮层纹状体网络活动的早期改变	Badreddine, N.	PDF	N/A	Early alterations of motor learning and corticostriatal network activity in a Huntington's disease mouse model
阿尔茨海默病相关基因型对老年小鼠慢性诱发性癫痫结果和抗癫痫药物活性的影响存在差异	Knox, K.	PDF	N/A	Alzheimer's disease-associated genotypes differentially influence chronic evoked seizure outcomes and antiseizure medicine activity in aged mice
驼背时间转录因子决定了果蝇NB5-2谱系中间神经元的分子身份、形态和突触前靶向。	Pollington, H. Q.	PDF	N/A	The Hunchback temporal transcription factor determines interneuron molecular identity, morphology, and presynapse targeting in the Drosophila NB5-2 lineage
动物声学交流保持着一种普遍的最优节奏	Piette, T.	PDF	N/A	Animal acoustic communication maintains a universal optimum rhythm
雌性大鼠性行为的时间交配模式	Oyem, J. C.	PDF	N/A	The temporal copulatory patterns of female rat sexual behavior
钾通道模拟中的电荷缩放：电导、离子占据、电压响应与选择性	Hui, C.	PDF	N/A	Charge Scaling in Potassium Channel Simulations: Conductance, Ion Occupancy, Voltage Response, and Selectivity
基于化学交换饱和转移的蛋白质次要构象状态精确推断的NMR实验条件自主自适应优化	Kasai, T.	PDF	N/A	Autonomous adaptive optimization of NMR experimental conditions for precise inference of minor conformational states of proteins based on chemical exchange saturation transfer
组蛋白H3作为核小体核心颗粒中的氧化还原开关：来自分子建模的见解	Karami, Y.	PDF	N/A	Histone H3 as a redox switch in the nucleosome core particle: insights from molecular modeling
在右美托咪定诱导意识丧失期间大脑连接性和神经血管动力学的变化	Fotiadis, P.	PDF	N/A	Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness
大脑“暗能量”之谜升级：FDG摄取、递送和磷酸化，及其与静息态脑活动的耦合	Volpi, T.	PDF	N/A	The brain's "dark energy" puzzle upgraded: FDG uptake, delivery and phosphorylation, and their coupling with resting-state brain activity
复杂的慢波在5-MeO-DMT作用下彻底重塑了人类大脑的动态。	Blackburne, G.	PDF	N/A	Complex slow waves radically reorganise human brain dynamics under 5-MeO-DMT
与二值化的病灶图像相比，连续的病灶图像能更准确地预测中风后的结果。	Hope, T. M. H.	PDF	N/A	Continuous lesion images drive more accurate predictions of outcomes after stroke than binary lesion images
大鼠脊髓损伤中基于间充质干细胞衍生的细胞外囊泡疗法的局部细胞因子变化	Kabdesh, I.	PDF	N/A	Local cytokine changes in response to mesenchymal stem cell-derived extracellular vesicles-based therapy in rat spinal cord injury
调和感觉衰减与增强：自我生成的感觉反馈的时间动态	Suzuishi, Y.	PDF	N/A	Reconcile sensory attenuation and enhancement: The temporal dynamics of self-generated sensory feedback
神经肽依赖的尖峰时间精确性和昼夜节律输出神经元的可塑性	Chong, B.	PDF	N/A	Neuropeptide-dependent spike time precision and plasticity in circadian output neurons
在观察动作时，空间信息和解剖结构信息的处理具有不同的时间尺度	Baptiste, W. M.	PDF	N/A	Separate timescales for spatial and anatomical information processing during action observation
成年大鼠中的多重情境辨别：性别差异及厌恶记忆的时间依赖性泛化动态	Alves, F. N. L.	PDF	N/A	Multiple context discrimination in adult rats: sex variability and dynamics of time-dependent generalization of an aversive memory
研究非人类灵长类动物三叉神经元机械激活电流	Lindquist, K.	PDF	N/A	Investigating Mechanically Activated Currents from Trigeminal Neurons of Non-Human Primates
小鼠嗅觉感觉神经元轴突内源性再生的区域性缺陷	Kunkhyen, T.	PDF	N/A	Regional deficits in endogenous regeneration of mouse olfactory sensory neuron axons
突触前丝状伪足形成动突触，并调节膜力学以促进同步神经传递和癫痫发作。	Jain, A.	PDF	N/A	Presynaptic filopodia form kinapses and modulate membrane mechanics for synchronous neurotransmission and seizure generation.
视觉皮层中附近刺激之间的抑制性相互作用反映了拥挤现象。	Soo, L.	PDF	N/A	Suppressive interactions between nearby stimuli in visual cortex reflect crowding
氯胺酮通过小鼠中Ca2+通透性AMPA受体的表达逆转慢性应激引起的行为变化	Flowers, J. C.	PDF	N/A	Ketamine reverses chronic stress-induced behavioral changes via the expression of Ca2+-permeable AMPA receptors in mice
驱动蛋白自抑制需要肘部磷酸化	Chen, G.	PDF	N/A	Kinesin Autoinhibition Requires Elbow Phosphorylation
通过机器学习模型进行可扩展且可解释的疾病预测的高维生物标志物识别	Dai, Y.	PDF	N/A	High-dimensional Biomarker Identification for Scalable and Interpretable Disease Prediction via Machine Learning Models
通过可解释机器学习洞察心力衰竭代谢标志物	Baron, C.	PDF	N/A	Insights into Heart Failure Metabolite Markersthrough Explainable Machine Learning
斑马鱼模型预测乳腺癌患者化疗反应：迈向个性化医疗的共临床研究	Mendes, R. V.	PDF	N/A	Zebrafish Avatar-test predicts patient's tumor response to chemotherapy in breast cancer: a co-clinical study towards personalized medicine
绘制乳腺癌在肺和肝转移的生态位	Sznurkowska, M. K.	PDF	N/A	Mapping the niche of breast cancer metastases in lung and liver
不同综合施肥水平对埃塞俄比亚南部瓦切莫大学大蒜（Allium sativum L.）产量和品质的影响	Shumbulo, A.	PDF	N/A	Garlic (Allium sativum L.) yield and quality as affected by different integrated fertilizer levels at Wachemo university, southern Ethiopia
树木高度与膨压限制：叶表皮细胞解剖学无证据支持	Aleman-Sancheschulz, G.	PDF	N/A	Turgor limitation of tree height: no evidence from leaf epidermal cell anatomy
阿片类药物使用者对奖励的前中部扣带回反应迟钝，通过前额叶经颅磁刺激可恢复正常	Biernacki, K.	PDF	N/A	Blunted anterior midcingulate response to reward in opioid users is normalized by prefrontal transcranial magnetic stimulation
对比功能连接定义了重度抑郁症中神经生理学指导的症状维度	Zhu, H.	PDF	N/A	Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depression
在离线期间的海马体涟漪能够预测人类的运动序列学习	Chen, P.-C.	PDF	N/A	Hippocampal ripples during offline periods predict human motor sequence learning
探索Instagram在新一代中的教育潜力：一项关于“领养细菌”影响的研究	Rodrigues Cintra Armellini, B.	PDF	N/A	Exploring the Educational Potential of Instagram in the New Generations: A Study on the Impact of "Adopt a Bacterium"
冰川消退对生态系统发育及碳动态的影响	Ceresa, E.	PDF	N/A	Glacier Retreat Effects On Ecosystem Development And Carbon Dynamics
揭示“被遗忘的民族”的起源与基因构成：一项关于喀尔巴阡盆地萨尔马提亚时期人口的研究	Schütz, O.	PDF	N/A	Unveiling the Origins and Genetic Makeup of the 'Forgotten People': A Study of the Sarmatian-Period Population in the Carpathian Basin
近东血统进入意大利中部的时间早于罗马帝国的建立。	Ravasini, F.	PDF	N/A	The arrival of the Near Eastern ancestry in Central Italy predates the onset of the Roman Empire
利用神经不应期去除电刺激伪影的方法：通过对比阴极和阳极刺激进行验证	Nakhmani, A.	PDF	N/A	A Method for Electrical Stimulus Artifact Removal Exploiting Neural Refractoriness: Validation by Contrasting Cathodic and Anodic Stimulation
Nutri Complex 150+：一种新的面部年轻化有效方法	Privitera, A.	PDF	N/A	Nutri Complex 150+: a new and effective approach to facial rejuvenation
HIV-1出芽需要氧化还原酶MICAL1介导的皮质肌动蛋白解聚	Serrano, T.	PDF	N/A	HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1
ASCL1介导的染色质结合和基因激活的独特增殖和神经元程序具有细胞周期阶段特异性	Beckman, W. F.	PDF	N/A	Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific
由磷脂1,2-二油酰基-sn-甘油-3-磷酸乙醇胺组成的脂质纳米颗粒封装的Spike mRNA疫苗在仓鼠中诱导了强大的B细胞和T细胞反应，这些反应与对COVID-19的保护相关。	Quadiri, A.	PDF	N/A	Spike mRNA Vaccine Encapsulated in a Lipid Nanoparticle Composed of Phospholipid 1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine Induced Potent B- and T-cell Responses Associated with Protection against COVID-19 in Hamsters
FungAMR：真菌中抗菌药物耐药性突变的综合概述	Bedard, C.	PDF	N/A	FungAMR: A comprehensive portrait of antimicrobial resistance mutations in fungi
土壤水分对农业土壤微生物多样性及其酶活性的影响	Bogati, K.	PDF	N/A	Impact of soil moisture on microbial diversity and their enzyme activity on agricultural soil
建立了一种慢性铜绿假单胞菌小鼠肺部感染模型，模拟了人类囊性纤维化的病理生理学和炎症反应。	Vaillancourt, M.	PDF	N/A	A chronic Pseudomonas aeruginosa mouse lung infection modeling the pathophysiology and inflammation of human cystic fibrosis
基因组间隔识别码（GenomicGapID）：利用保守基因组位点的空间分布进行广谱微生物鉴定	Asthana, V.	PDF	N/A	GenomicGapID: Leveraging Spatial Distribution of Conserved Genomic Sites for Broad-Spectrum Microbial Identification
慢性感染可能导致类似SARS-CoV-2的病毒进化爆发，而没有上位效应。	Rodriguez-Horta, E.	PDF	N/A	Chronic infections can generate SARS-CoV-2-like bursts of viral evolution without epistasis
FAN1缺陷促进亨廷顿病的结构和分子基础	Pluciennik, A.	PDF	N/A	Structural and molecular basis of FAN1 defects in promoting Huntington's disease
人类外泌体的结构延伸通过最小界面实现	Xu, H. D.	PDF	N/A	Structural extension of the human exocyst is enabled by a minimal interface
用于杆状病毒系统和酵母的多基因载体模块化克隆	Lai, Z.	PDF	N/A	Modular cloning of multigene vectors for the baculovirus system and yeast
基于细胞的高内涵方法用于SARS-CoV-2中和，识别出独特的单克隆抗体和PI3K通路抑制剂。	Cabel, C. R.	PDF	N/A	Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors.
基于机器学习的3' UTR设计以提高mRNA稳定性	Morrow, A. K.	PDF	N/A	ML-driven design of 3' UTRs for mRNA stability
分子状态在胡须皮质神经元细胞类型发育和可塑性中的基础	Butrus, S.	PDF	N/A	Molecular states underlying neuronal cell type development and plasticity in the whisker cortex
恶性疟原虫Vps16同源物的特征，Vps-2 C连接复合体成员之一。	Galaup, T.	PDF	N/A	Characterization of the Plasmodium falciparum homologue of Vps16, a member of the Vps-2 C tethering complex.
细菌鞭毛马达速度对质子动力势的非线性依赖性及其对游泳的影响	Krasnopeeva, E.	PDF	N/A	Nonlinear dependency of the bacterial flagellar motor speed on proton motive force and its consequences for swimming
解码HIV诱导的CPSF6点状结构及其与核斑点的融合过程	Tomasini, C. D.	PDF	N/A	Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle
TGF-beta介导的JunB-HBZ核转位是HTLV-1诱导白血病的关键驱动因素	Yasunaga, J.	PDF	N/A	JunB-HBZ nuclear translocation by TGF-beta is a key driver in HTLV-1-mediated leukemogenesis
人类尿液中尿路致病细菌的代谢组学调查	Chan, C. C.	PDF	N/A	Metabolomics survey of uropathogenic bacteria in human urine
扩展中的松露环境：对旧和新块菌属大块菌栖息地中微生物动态的研究	Rondolini, M.	PDF	N/A	The expanding truffle environment: a study of the microbial dynamics in old and new Tuber magnatum Picco habitat
洋葱叶和鳞茎组织中伯克霍尔德菌（Burkholderia gladioli）的独特致病机制	Paudel, S.	PDF	N/A	Distinct Virulence Mechanisms of Burkholderia gladioli in Onion Foliar and Bulb Scale Tissues
种族和民族对口腔微生物群的多样性和特征的影响	Wang, Q.	PDF	N/A	Diversity and characteristics of the oral microbiome influenced by race and ethnicity
转基因水稻品系中甲烷排放量的减少与根际微生物氢循环的改变有关	Shi, L.-D.	PDF	N/A	Reduced methane emissions in transgenic rice genotypes are associated with altered rhizosphere microbial hydrogen cycling
DNA修复基因uvrA发生临床突变，使结核分枝杆菌在宿主体内获得生存优势。	Saba Naz,	PDF	N/A	A clinical mutation in uvrA, a DNA repair gene, confers survival advantage to Mycobacterium tuberculosis in the host
Primosomal蛋白PriC通过绕过DnaA-DnaB相互作用步骤，在oriC处加载DnaB解旋酶，从而缓解复制起始压力。	Yoshida, R.	PDF	N/A	Primosomal protein PriC rescues replication initiation stress by bypassing the DnaA-DnaB interaction step for DnaB helicase loading at oriC
突变剂对硝基呋喃妥因耐药性发展的进化风险分析	Kettlewell, R.	PDF	N/A	Evolutionary risk analysis of mutators for the development of nitrofurantoin resistance
巨型病毒创造亚细胞环境以克服密码子-tRNA不匹配	Zhang, R.	PDF	N/A	Giant virus creates subcellular environment to overcome codon-tRNA mismatch
用于量化病毒准种遗传多样性的相似性加权熵	Wu, J.	PDF	N/A	Similarity-weighted entropy for quantifying genetic diversity in viral quasispecies
患者对达托霉素耐药性的获得导致果蝇的毒力降低	Lamy, B.	PDF	N/A	Acquisition of daptomycin resistance in patients results in decreased virulence in Drosophila
纤毛虫藻类Heterosigma akashiwo的病毒感染不仅影响了细胞内有机物的组成，还改变了沿海原核生物群落的动态。	Takebe, H.	PDF	N/A	Viral infection to the raphidophycean alga Heterosigma akashiwo affects both intracellular organic matter composition and dynamics of a coastal prokaryotic community
R5噬菌体在高风险铜绿假单胞菌分离株优势中的作用	Zhang, L.	PDF	N/A	Role of R5 Pyocin in the Predominance of High-Risk Pseudomonas aeruginosa Isolates
沙门氏菌利用宿主和细菌来源的β-丙氨酸在宿主巨噬细胞内进行复制	Ma, S.	PDF	N/A	Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages
DNA拓扑异构酶I在E. coli中作为转录延伸的超螺旋传感器	Vidmar, V.	PDF	N/A	DNA topoisomerase I acts as supercoiling sensor for transcription elongation in E. coli
线粒体DNA释放与cGAS-STING通路的激活在致死性Stx12敲除小鼠中的作用	Kang, J.-S.	PDF	N/A	Mitochondrial DNA Release and Activation of the cGAS-STING Pathway in Lethal Stx12 Knockout Mice
影响埃及伊蚊和白纹伊蚊（双翅目：蚊科）的环境和人为因素，重点在于自然感染和传播：对哥伦比亚新兴媒介的启示。	Mantilla, J. S.	PDF	N/A	Environmental and anthropic factors influencing Aedes aegypti and Aedes albopictus (Diptera: Culicidae), with emphasis on natural infection and dissemination: Implications for an emerging vector in Colombia.
野生、自由生活的家鼠社会群体中的发声交流具有季节性。	Jourjine, N.	PDF	N/A	Vocal communication is seasonal in social groups of wild, free-living house mice
利用局部超荷电病毒衣壳进行阴离子环二核苷酸STING激动剂的细胞质递送	Huang, P.	PDF	N/A	Cytosolic delivery of anionic cyclic dinucleotide STING agonists with locally supercharged viral capsids
计算设计一种用于全细胞生物转化的热稳定从头生物催化剂	Elaily, W.	PDF	N/A	Computational design of a thermostable de novo biocatalyst for whole cell biotransformations
TAOK2 在16p11.2缺失和重复携带者中驱动相反的纤毛长度缺陷	Ferreccio, A.	PDF	N/A	TAOK2 Drives Opposing Cilia Length Deficits in 16p11.2 Deletion and Duplication Carriers
局部皮质抑制性子网络的形态受到锥体神经元前体类型的影响。	Gothard, G.	PDF	N/A	Local cortical inhibitory subnetworks are shaped by pyramidal neuron progenitor type
言语产生中从计划到执行的神经机制	Duraivel, K.	PDF	N/A	Neural mechanisms of the transition from planning to execution in speech production
多重需求网络中信息编码与交换的时空特性分析	Karimi-Rouzbahani, H.	PDF	N/A	Spatiotemporal characterisation of information coding and exchange in the multiple demand network
奖励和惩罚的偶然性转变揭示了腹侧被盖区多巴胺神经元和GABA神经元在行为灵活性中的不同作用	Lefner, M. J.	PDF	N/A	Reward and punishment contingency shifting reveals distinct roles for VTA dopamine and GABA neurons in behavioral flexibility
APOE4影响皮层神经发育并改变人脑类器官中的网络形成	Meyer-Acosta, K. K.	PDF	N/A	APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoids
纹状体细胞类型特异性分子特征揭示了肌张力障碍模型中的治疗靶点	Roman, K. M.	PDF	N/A	Striatal cell-type-specific molecular signatures reveal therapeutic targets in a model of dystonia
感觉皮层中神经元的电学多样性	Calcini, N.	PDF	N/A	Electrical diversity of neurons in sensory cortices
开发具有广泛治疗潜力的临床可行非肌肉肌球蛋白II小分子抑制剂	Radnai, L.	PDF	N/A	Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential
香烟烟雾会损害酿酒酵母的胞吞过程。	shukla, A.	PDF	N/A	Cigarette smoke impairs the endocytotic process in Saccharomyces cerevisiae
时空控制多层同轴流在带有级联喷嘴的3D打印微通道中	Werner, H.	PDF	N/A	Spatiotemporal control of a multilayered co-axial flow in a 3D printed microchannel with cascaded nozzles
TPLATE复合体的结构支架在植物胞吞过程中使膜发生变形。	Kraus, J. M.	PDF	N/A	The structural scaffold of the TPLATE complex deforms the membrane during plant endocytosis
催产素Gαi信号诱导的杏仁核星形胶质细胞过程回缩塑造行为应激反应	Baudon, A.	PDF	N/A	Oxytocin Gαi signaling-induced amygdala astrocytes processes retraction shapes behavioral stress response
揭示人结肠上皮类器官中细胞分裂与细胞外基质之间的机械相互作用：基于数字体积相关技术的四维研究	Magne, L.	PDF	N/A	Unveiling mechanical interactions between cell division and extracellular matrix in human colonic epithelium organoids: A 4D study using DVC
有丝分裂后依赖PP2A-Ankle2的核重组机制	Li, J.	PDF	N/A	Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis
LRRK2突变的微胶质细胞在受到神经黑色素激活时会触发多巴胺能神经退行性变。	Blasco-Agell, L.	PDF	N/A	LRRK2-mutant microglia trigger dopaminergic neurodegeneration when activated by neuromelanin
急性GARP耗竭会破坏囊泡运输，导致分拣、分泌和O-糖基化出现严重缺陷。	Khakurel, A.	PDF	N/A	Acute GARP depletion disrupts vesicle transport leading to severe defects in sorting, secretion, and O-glycosylation
# BioRxiv 2024-10-06 Papers

标题	作者	PDF链接	代码仓库	Title
乳腺癌中的DNA甲基化特征：系统综述与Meta分析	Trasierras-Fresco, A. M.	PDF	N/A	DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis
启动听觉并行处理通路的细胞特化分子逻辑	Jing, J.	PDF	N/A	Molecular logic for cellular specializations that initiate the auditory parallel processing pathways
机械力在出生后小鼠肌腱发育中作为生物学线索的作用	Usami, Y.	PDF	N/A	Mechanical Force Works as a Biological Cue in Postnatal Murine Tendon Development
具有生物合成基因突变的肺炎链球菌可减弱疾病症状，但仍保留其对上皮细胞微侵袭和激活上皮细胞先天免疫的潜力。	Weight, C. M.	PDF	N/A	Streptococcus pneumoniae with biosynthesis gene mutations attenuate disease but retain their potential for epithelial microinvasion and epithelial innate immune activation
黑色素瘤中新诊断和进展相关的微RNA特征	Gomez-Martinez, H.	PDF	N/A	Novel diagnosis- and progression-related microRNA signatures in melanoma
通用细胞嵌入：细胞生物学的基础模型	Rosen, Y.	PDF	N/A	Universal Cell Embeddings: A Foundation Model for Cell Biology
通过对从相同原始读取数据中提取的保守核基因序列和整个叶绿体基因组的综合研究，探讨亚家族的进化历程。	Witharana, E. P.	PDF	N/A	Comprehensive study of subfamily evolution through sequences of conserved nuclear genes and whole chloroplast genomes extracted from the same raw read data
过氧化物酶体增殖物激活受体γ介导的脂质生物合成增强促进了耐药肝细胞环境中结核分枝杆菌的生长。	Sarkar, B.	PDF	N/A	PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment.
α-突触核蛋白与NOD2相互作用及RIPK2激活在帕金森病中驱动小胶质细胞诱导的神经炎症	Seo, B. A.	PDF	N/A	Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease
二元性状模型揭示了HIV-1逃逸T细胞反应的适应性影响	Gao, Y.	PDF	N/A	A binary trait model reveals the fitness effects of HIV-1 escape from T cell responses
gRNAde：用于3D RNA逆向设计的几何深度学习	Joshi, C. K.	PDF	N/A	gRNAde: Geometric Deep Learning for 3D RNA inverse design
膜定位序列基序对于大肠杆菌RNase E表现出隐性复活是必需的。	Basak, P.	PDF	N/A	The membrane-targeting-sequence motif is required for exhibition of recessive resurrection in Escherichia coli RNase E
静息状态下不规则的瞳孔波动可预测视觉注意的定向	Wang, R.	PDF	N/A	Aperiodic pupil fluctuations at rest predict orienting of visual attention
分支增强了嗅觉外周的时间信息编码	Choi, K.	PDF	N/A	Bifurcation enhances temporal information encoding in the olfactory periphery
GPCR的选择性激活：分子动力学显示西波莫德结合但未能激活S1PR2，与S1PR1不同	Soniya, K.	PDF	N/A	Selective Activation of GPCRs: Molecular Dynamics Shows Siponimod Binds but Fails to Activate S1PR2 Unlike S1PR1
基因组变异的加性和部分显性效应有助于水稻杂种优势的形成	Dan, Z.	PDF	N/A	Additive and partially dominant effects from genomic variation contribute to rice heterosis
绿色植物的染色体数目与生殖生命周期：基于系统发生转录组学的视角	Dhakal, R.	PDF	N/A	Chromosome Numbers and Reproductive Life Cycles in Green Plants: A phylo-transcriptomic perspective
高效整合空间组学数据，实现联合域检测、匹配与对齐的stMSA方法	Shu, H.	PDF	N/A	Efficient integration of spatial omics data for joint domain detection, matching, and alignment with stMSA
丙酮酸激酶的变构效应通过诱导三羧酸循环涡流和葡萄糖U型转弯，抵抗高血糖、肥胖和炎症。	Zhang, X.	PDF	N/A	Pyruvate kinase allostery resist hyperglycemia, obesity and inflammation by inducing TCA vortex and glucose U turn
小脑如何自动化和协调无意识的运动序列？	Gilbert, M.	PDF	N/A	How does the cerebellum automate and coordinate unconscious motor sequences?
III型干扰素通过触发细胞死亡独立于STAT激活来抑制甲型流感病毒感染	Prus, W.	PDF	N/A	Type III interferons suppress influenza A virus infection independently of STAT activation by triggering cell death
scChat：基于大型语言模型的单细胞RNA测序分析上下文助手	Lu, Y.-C.	PDF	N/A	scChat: A Large Language Model-Powered Co-Pilot for Contextualized Single-Cell RNA Sequencing Analysis
BioLLMNet：利用专用跨LLM转换网络增强RNA相互作用预测	Tahmid, M. T.	PDF	N/A	BioLLMNet: Enhancing RNA-Interaction Prediction with a Specialized Cross-LLM Transformation Network
行为控制的类脑神经动力学通过强化学习得以发展	Codol, O.	PDF	N/A	Brain-like neural dynamics for behavioral control develop through reinforcement learning
第六层皮层丘脑神经元通过皮层间和皮层丘脑皮层通路诱发高伽马振荡	Russo, S.	PDF	N/A	Layer 6 corticothalamic neurons induce high gamma oscillations through cortico-cortical and cortico-thalamo-cortical pathways
人类腹侧颞叶皮层中感知和想象物体共享的代码	Wadia, V. S.	PDF	N/A	A shared code for perceiving and imagining objects in human ventral temporal cortex
人类腹侧颞叶皮层中感知和想象物体共享的代码	Wadia, V. S.	PDF	N/A	A shared code for perceiving and imagining objects in human ventral temporal cortex
更年期下丘脑衰老的转录组学洞察：人类和小鼠模型的比较分析	Bloom, J. C. B.	PDF	N/A	Transcriptomic Insights into Hypothalamic Aging During Menopause: A Comparative Analysis of Human and Mouse Models
家猫（Felis catus）对物体恒常性的认知：通过主人和陌生人的预期违背实验	Forman, J.	PDF	N/A	Object permanence in domestic cats (Felis catus) using violation-of-expectancy by owner and stranger
神经调节对沿单峰-跨峰梯度传播脑波的影响	Maki-Marttunen, V.	PDF	N/A	Neuromodulatory influences on propagation of brain waves along the unimodal-transmodal gradient
非人灵长类动物初级运动皮层中熟练连续运动的逐步巩固	Ohbayashi, M.	PDF	N/A	Gradual consolidation of skilled sequential movements in primary motor cortex of non-human primates
亲子脑相似性：性别组合中的特异性与共性——传递辐射个性给后代（TRIO）研究	Matsudaira, I.	PDF	N/A	Parent-offspring brain similarity: Specificities and commonalities across gender combinations - the Transmit Radiant Individuality to Offspring (TRIO) study
对行为库的完整描述揭示了斑马鱼幼鱼捕食行为的原则。	Rubinstein, Y.	PDF	N/A	A complete account of the behavioral repertoire uncovers principles of larval zebrafish hunting behavior
用于完整大脑中PTEN动态荧光寿命成像的基因编码生物传感器	Kagan, T.	PDF	N/A	Genetically encoded biosensor for fluorescence lifetime imaging of PTEN dynamics in the intact brain
果蝇在嗅觉导航过程中工作记忆与证据整合的神经动力学	Kathman, N. D.	PDF	N/A	Neural dynamics for working memory and evidence integration during olfactory navigation in Drosophila
南极磷虾（Euphausia superba）的行为活动由一个昼夜节律钟驱动，这为季节性时间调节提供了一种潜在的机制。	Hüppe, L.	PDF	N/A	A circadian clock drives behavioral activity in Antarctic krill (Euphausia superba) and provides a potential mechanism for seasonal timing
影响评估与原住民权利：芬兰穆杜斯亚夫里驯鹿放牧合作社林业对冬季牧场的累积影响评估	Saijets, J.	PDF	N/A	Impact assessment and indigenous rights: Cumulative impact assessment of forestry on winter pastures in Mudusjävri reindeer herding co-operative in Finland
视觉引导接近行为中的性二态性在青春期独特地出现	Gonzalez-Olvera, R.	PDF	N/A	SEXUAL-DIMORPHISM IN VISUALLY GUIDED APPROACH BEHAVIOR EMERGES UNIQUELY DURING ADOLESCENCE
与Vertec相比，Jumpster基于加速度计的应用程序在完成反向运动跳跃时的可靠性和有效性	Holman, M. E.	PDF	N/A	Reliability and Validity of the Jumpster accelerometer-based app compared to the Vertec when completing a countermovement jump
p53异构体具有高聚集倾向，能与伴侣蛋白相互作用，但缺乏与p53相互作用伙伴的结合能力。	Brdar, A.	PDF	N/A	p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners
年龄诱导的BMP信号通过抑制ICAT介导的Wnt通路来促进骨关节炎。	Kumar, B.	PDF	N/A	Age-induced BMP signaling inhibits the ICAT-mediated Wnt pathway to promote osteoarthritis.
Lgi3-4对IKur调控的新见解：对心房颤动的启示	Socuellamos, P. G.	PDF	N/A	Novel insights into IKur modulation by Lgi3-4: Implications in atrial fibrillation
PII1/MRC与拟南芥中的淀粉合成酶4（SS4）的相互作用抑制了SS4的酶活性。	Bossu, M.	PDF	N/A	PII1/MRC interaction with Starch Synthase 4 (SS4) from Arabidopsis thaliana inhibits SS4 enzymatic activity
化学定义的脂质饮食揭示了基因组最小细胞中脂质组重塑的多功能性	Safronova, N.	PDF	N/A	Chemically defined lipid diets reveal the versatility of lipidome remodeling in genomically minimal cells
油质真菌优化见解——Umbelopsis sp. WA50703的全基因组代谢重构与分析	Dziurzynski, M.	PDF	N/A	Insights into optimization of oleaginous fungi - genome-scale metabolic reconstruction and analysis of Umbelopsis sp. WA50703
在神经形态硬件上实现的生物学上逼真的新皮层计算基元提升了视觉变换器的性能	Iqbal, A.	PDF	N/A	Biologically Realistic Computational Primitives of Neocortex Implemented on Neuromorphic Hardware Improve Vision Transformer Performance
利用单细胞RNA测序生成稳健的微胶质细胞衰老时钟	Stanley, N.	PDF	N/A	Leveraging Single-Cell RNA-Seq to Generate Robust Microglia Aging Clocks
在小鼠视觉皮层胚胎期和出生后发育过程中持续的细胞类型多样化	Gao, Y.	PDF	N/A	Continuous cell type diversification throughout the embryonic and postnatal mouse visual cortex development
工作记忆提取中的速度与准确性权衡及老年男女双侧楔前叶的差异	Esiaka, D.	PDF	N/A	Differential Speed and Accuracy Trade-off in Working Memory Retrieval and Bilateral Precuneus between Older Men and Women
大豆（Glycine max (L.) Merril）种质资源的遗传多样性和群体结构。	SILUE, T.	PDF	N/A	Genetic diversity and population structure of soybean (Glycine max (L.) Merril) germplasm.
更新后的锥虫核孔及其相关蛋白图谱	Gabiatti, B. P.	PDF	N/A	An updated map of the trypanosome nuclear pore and its associated proteins
疟原虫HOPS/CORVET复合体对于内吞作用和入侵器官的功能至关重要。	Mesen-Ramirez, P.	PDF	N/A	Malaria parasite HOPS/CORVET complexes are critical for endocytosis and invasion organelles function
MicroBayesAge：一种利用微阵列数据预测表观遗传年龄的最大似然方法	Nolan, N.	PDF	N/A	MicroBayesAge: A Maximum Likelihood Approach to Predict Epigenetic Age Using Microarray Data
pLM-DBPs：利用蛋白质语言模型嵌入增强植物中DNA结合蛋白预测	Pokharel, S.	PDF	N/A	pLM-DBPs: Enhanced DNA-Binding Protein Prediction in Plants Using Embeddings From Protein Language Models
溶剂动力学与蛋白质动力学的耦合有助于驱动表皮生长因子受体（EGFR/ErbB1/HER1）激酶域中外显子19缺失突变体的功能差异	Patil, K.	PDF	N/A	Coupled Solvent Dynamics and Protein Dynamics Help Drive Functional Differences in Exon-19 Deletion Mutants in the Epidermal Growth Factor Receptor (EGFR/ErbB1/HER1) Kinase Domain
小麦条锈病抗性基因Yr9源自黑麦，是一个高度保守的NLR簇中的CC-NBS-LRR基因。	Yu, Y.	PDF	N/A	Wheat stripe rust resistance gene Yr9, derived from rye, is a CC-NBS-LRR gene in a highly conserved NLR cluster
耦合生长的微生物生物合成动物色素黄蝶呤	Bushin, L. B.	PDF	N/A	Growth-coupled microbial biosynthesis of the animal pigment xanthommatin
单细胞分辨率图谱揭示了先天样淋巴细胞对土拉弗朗西斯菌感染的反应，并揭示了MAIT细胞在预防类土拉菌病中的作用	JOYCE, S.	PDF	N/A	Single-cell resolution map of innate-like lymphocyte response to Francisella tularensis infection reveals MAIT cell role in protection from tularemia-like disease
二氢乳清酸脱氢酶抑制剂与4'-氟尿苷的广谱抗病毒活性具有协同作用	Schrell, L.	PDF	N/A	Inhibitors of dihydroorotate dehydrogenase synergize with the broad antiviral activity of 4'-fluorouridine
便携式现场DNA测序技术用于快速检测病原体及抗菌药物耐药性：概念验证研究	Pillay, S.	PDF	N/A	Portable In-Field DNA Sequencing for Rapid Detection of Pathogens and Antimicrobial Resistance: A Proof-of-Concept Study
宿主遗传及其/或其微生物群对杂交无胸腺裸鼠棒状杆菌相关角化过度严重程度的影响	Michelson, A.	PDF	N/A	The Impact of Host Genetics and/or its Microbiota on the Severity of Corynebacterium-Associated Hyperkeratosis in Outbred Athymic Nude Mice
基于荧光的CRISPR干扰系统用于分枝杆菌中可控的基因抑制和活体单细胞成像	Laudouze, J.	PDF	N/A	Fluorescence-based CRISPR interference system for controlled genetic repression and live single-cell imaging in mycobacteria
光激活分子纳米机器在耻垢分枝杆菌中的杀菌机制：病原菌模型研究	Galbadage, T.	PDF	N/A	Microbicidal Mechanisms for Light-Activated Molecular Nanomachines in Mycobacterium smegmatis: A Model for Pathogenic Bacteria
哺乳细胞中热休克反应调控中mRNA操纵子形成的保守性	Pataki, E.	PDF	N/A	Conservation of mRNA operon formation in the control of the heat shock response in mammalian cells
Fn14信号在成年骨骼肌修复过程中调控卫星细胞的自我更新和扩增	Tomaz Da Silva, M.	PDF	N/A	Fn14 signaling regulates satellite cell self-renewal and expansion during adult skeletal muscle repair
TWEAK/Fn14信号传导促进癌症恶病质期间的骨骼肌消耗。	Tomaz da Silva, M.	PDF	N/A	The TWEAK/Fn14 signaling promotes skeletal muscle wasting during cancer cachexia
鉴定出一种新的恶性疟原虫E2泛素结合酶	Smith, C.	PDF	N/A	Identification of a new Plasmodium falciparum E2 ubiquitin conjugating enzyme
单细胞成像揭示了Bck2在酿酒酵母细胞大小适应营养挑战中的关键作用	Chadha, Y.	PDF	N/A	Single-cell imaging reveals a key role of Bck2 in budding yeast cell size adaptation to nutrient challenges
插入偏倚对piRNA簇中转座元件侵入的影响	Pritam, S.	PDF	N/A	The impact of insertion bias into piRNA clusters on the invasion of transposable elements
合作塑造了细菌生态位宽度进化和多样化模式	Hao, C.	PDF	N/A	Cooperation shapes bacterial niche breadth evolution and patterns of diversification
黑麦1RS染色体上编码CC-NBS-LRR蛋白的基因赋予小麦条锈病抗性	Han, F.	PDF	N/A	Gene encoding CC-NBS-LRR protein on rye chromosome 1RS confers wheat stripe rust resistance
单细胞RNA测序揭示小鼠动脉粥样硬化过程中血管外膜成纤维细胞的改变	Fries, L. E.	PDF	N/A	Single-Cell RNA-Seq Reveals Adventitial Fibroblast Alterations during Mouse Atherosclerosis
使用Gnodes测量动植物基因组的DNA含量，长话短说。	Gilbert, D.	PDF	N/A	Measuring DNA contents of animal and plant genomes with Gnodes, the long and short of it.
计算洞察C肽灵活性驱动的迷你胰岛素在受体结合中的变构行为	AYAN, E.	PDF	N/A	Computational Insights into the Allosteric Behavior of Mini-Insulin in Receptor Binding Driven by C-Peptide Mobility
白茶通过调节大鼠体内的Apelin和胰岛素水平，缓解了与肥胖相关的代谢紊乱。	SÜMER, A.	PDF	N/A	White Tea Mitigates Obesity-Related Metabolic Disorders Through Apelin and Insulin Modulation in Rats
P450酶催化的无前导核糖体肽的联芳基大环化	Liu, R.	PDF	N/A	P450-Catalyzed Biaryl Macrocyclization of Leaderless Ribosomal Peptides
反应性氮物质（RNS）及其与反应性氧物质（ROS）在pH中性的高强度等离子体活化水中的反应中间体，决定了其对ESKAPE病原体的抗菌活性。	Mukherjee, D.	PDF	N/A	Reactive nitrogen species (RNS) and its reaction intermediates with reactive oxygen species (ROS) in pH-neutral high-strength plasma-activated water determines the antimicrobial activity against ESKAPE Pathogens
通过共享字典学习进行微生物组数据整合	Yuan, B.	PDF	N/A	Microbiome Data Integration via Shared Dictionary Learning
Inv(16)癌基因CBFB::MYH11的丢失消除了血液和脾脏中的白血病，但未影响骨髓中的白血病。	Panda, S.	PDF	N/A	Loss of the Inv(16) Oncogene CBFB::MYH11 Eliminates Leukemia from the Blood and Spleen, but not the Bone Marrow
绘制PTEN突变图谱：肺癌的结构和功能驱动因素	Hossain, M. U.	PDF	N/A	Mapping the PTEN Mutation Landscape: Structural and Functional Drivers of Lung Cancer
从头设计具有设计配比的α-螺旋肽通道	Niitsu, A.	PDF	N/A	De novo design of α-helical peptide channels with designer stoichiometry
通过整合活细胞和合成细胞实现混合三维培养的自组装	Piernitzki, N.	PDF	N/A	Self-assembly of hybrid 3D cultures by integrating living and synthetic cells
普拉梭菌（Faecalibacterium prausnitzii）在人类单核细胞中诱导抗炎反应和代谢重编程	Danne, C.	PDF	N/A	Faecalibacterium prausnitzii induces an anti-inflammatory response and a metabolic reprogramming in human monocytes
膜表达增强病毒衣壳蛋白的折叠、多聚体结构形成及免疫原性	Cui, J.	PDF	N/A	Membrane Expression Enhances Folding, Multimeric Structure Formation, and Immunogenicity of Viral Capsid Proteins
大肠杆菌对阿莫西林的遗传适应性：dinB和katE的有限作用	Teichmann, L. H.	PDF	N/A	Genetic Adaptation to Amoxicillin in Escherichia coli: The Limited Role of dinB and katE
埃博拉病毒基质蛋白引发炎症激活的新机制与埃博拉病毒毒力相关	Yamaoka, S.	PDF	N/A	Novel Mechanism of Inflammatory Activation by Ebola Virus Matrix Protein Linked to the Ebolavirus Virulence
气道上皮连接减弱和中性粒细胞弹性蛋白酶释放增强，共同导致了肺炎球菌性肺炎后年龄依赖性的菌血症风险增加。	Xu, S.	PDF	N/A	Weakened airway epithelial junctions and enhanced neutrophil elastase release contribute to age-dependent bacteremia risk following pneumococcal pneumonia
土壤微生物群的扰动阻碍了垂穗草（Bouteloua curtipendula）的生长，并增加了土壤微生物病原体的相对丰度。	Hobbs, A.	PDF	N/A	Soil microbiome perturbation impedes growth of Bouteloua curtipendula and increases relative abundance of soil microbial pathogens
果蝇piRNA通路中蛋白质相互作用的反复创新	Riedelbauch, S.	PDF	N/A	Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway
胶质母细胞瘤中的拼接失调改变了与细胞迁移相关基因的功能	Seong, M.	PDF	N/A	Splicing dysregulation in glioblastoma alters the function of cell migration-related genes
土地利用变化影响全球生物多样性热点地区根-真菌网络的连通性	Carneiro de Melo Moura, C.	PDF	N/A	Land-use changes impact root-fungal network connectivity in a global biodiversity hotspot
值得深入探讨的话题：食果鱼类牙齿压痕的力学原理	Rosen, J.	PDF	N/A	Something to sink your teeth into: the mechanics of tooth indentation in frugivorous fishes
基因组和进化证据表明草类异源多倍体短柄草（Brachypodium hybridum）具有干旱适应性	Wang, Y.	PDF	N/A	Genomic and evolutionary evidence for drought adaptation of grass allopolyploid Brachypodium hybridum
一种古老的溶菌酶存在于扁盘动物中	Berndt, H.	PDF	N/A	An ancient lysozyme in placozoans
快速且经济高效地生产高质量昆虫基因组序列	Gilligan, J.	PDF	N/A	Rapid and cost-effective production of high-quality insect genome sequences
基于基因共表达和共进化的蛋白质-蛋白质直接相互作用及稳定复合物的预测与发现	Miglionico, P.	PDF	N/A	Prediction and discovery of protein-protein direct interactions and stable complexes based on gene co-expression and co-evolution
如何为病毒蛋白选择最佳的零样本模型？	Yu, Y.	PDF	N/A	How to select the best zero-shot model for the viral proteins?
ProteinAligner：一种用于蛋白质基础模型的多模态预训练框架	Zhang, L.	PDF	N/A	ProteinAligner: A Multi-modal Pretraining Framework for Protein Foundation Models
E(Q)AGNN-PPIS：用于蛋白质-蛋白质相互作用位点预测的注意力增强等变图神经网络	Animesh, A.	PDF	N/A	E(Q)AGNN-PPIS: Attention Enhanced Equivariant Graph Neural Network for Protein-Protein Interaction Site Prediction
Tau加速微管网格中的微管蛋白交换	Biswas, S.	PDF	N/A	Tau accelerates tubulin exchange in the microtubule lattice
集体变形虫样动力学驱动耐药性卵巢癌细胞的侵袭	Goutham, S.	PDF	N/A	Collective amoeboid dynamics drives colonization of drug-resistant ovarian cancer cells
内源性亨廷顿蛋白聚集体是一个巨大的有组织的支架，为突变亨廷顿蛋白损害的高尔基体提供模板。	Ma, L.	PDF	N/A	Endogenous Huntingtin aggregates are a huge organized scaffold and mold for Golgi apparatus impaired by mutant Huntingtin protein
低R:FR处理下的玉米植株挥发物增加了其邻近植株食草动物诱导的挥发物排放	Escobar Bravo, R.	PDF	N/A	Volatiles from low R:FR-treated maize plants increase the emission of herbivore-induced plant volatiles in their neighbors
水热预处理使泥炭易于酶解糖化。	Thomsen, J.	PDF	N/A	Hydrothermal pretreatment renders peat susceptible to enzymatic saccharification
温度对桃蚜（Myzus persicae）生活史特征及其在马铃薯作物中传播马铃薯Y病毒（PVY）效率的影响	Sokame, B. M.	PDF	N/A	Effects of temperature on the life-history traits of Myzus persicae and its efficiency in transmitting potato virus Y (PVY) in potato crops
预测京都基因与基因组百科全书中定义的所有通路及其相关化合物条目的通路参与情况	Huckvale, E. D.	PDF	N/A	Predicting The Pathway Involvement For All Pathway and Associated Compound Entries Defined in the Kyoto Encyclopedia of Gene and Genomes
金丝雀交配季节的歌声在有序与无序之间游走	Levin, S.	PDF	N/A	Canary Mating Season Songs Move Between Order and Disorder
靶向DNA-PK是一种高度保守的痘病毒先天免疫逃避机制	Oliveira, M.	PDF	N/A	Targeting DNA-PK is a highly conserved poxvirus innate immune evasion mechanism
决策分析显示，基于社区的监测在马达加斯加具有科学和经济价值。	Soifer, L.	PDF	N/A	Decision analysis shows scientific and economic value of community-based monitoring in Madagascar
雄性果蝇选择体型较大的雌性作为配偶的遗传变异	Freed, G. S.	PDF	N/A	Genetic variation in male mate choice for large females in Drosophila melanogaster
验证Pocheina属（Acrasidae科，异鞭毛虫纲，挖掘类）导致在Acrasidae科内识别出三个主要谱系。	Tice, A. K.	PDF	N/A	Validating the genus Pocheina (Acrasidae, Heterolobosea, Excavata) leads to the recognition of three major lineages within Acrasidae
高纵横比氧化石墨烯：一种高效植物种子质粒DNA传递载体	Jiang, C.	PDF	N/A	High aspect ratio graphene oxide: a highly efficient plasmid DNA deliverer for plant seed
人类疾病中病毒转录调节因子的鉴定与目录	Citu, C.	PDF	N/A	Identification and catalogue of viral transcriptional regulators in human diseases
小角度散射测量信号的信息论优化	Rambo, R. P.	PDF	N/A	Information Theory Optimization of Signals from Small Angle Scattering Measurements
青春期雌性小鼠控制生育的下丘脑神经元中的神经可塑性	Zhang, Y.	PDF	N/A	Neuronal plasticity at puberty in hypothalamic neurons controlling fertility in female mice
肿瘤抑制因子NME1/NM23-H1调节NF-κB RelA的DNA结合	Shahabi, S.	PDF	N/A	Tumor suppressor NME1/NM23-H1 modulates DNA binding of NF-κB RelA
来自新型脊索瘤细胞系ARF-8的细胞外囊泡在与亲本细胞和人成骨细胞共培养时，促进了肿瘤发生微环境的改变。	Nguyen, K. N.	PDF	N/A	Extracellular vesicles from a novel chordoma cell line, ARF-8, promote tumorigenic microenvironmental changes when incubated with the parental cells and with human osteoblasts.
Rho激酶抑制剂对翼状胬肉细胞纤维化的抑制作用	Dai, J.	PDF	N/A	Inhibition of pterygium cell fibrosis by the Rho kinase inhibitor
一种基于纤连蛋白（FN）-丝素蛋白的三维细胞培养模型，作为子宫内膜异位症再利用抗纤维化药物候选物的筛选工具	Teworte, S.	PDF	N/A	A Fibronectin (FN)-Silk 3D Cell Culture Model as a Screening Tool for Repurposed Antifibrotic Drug Candidates for Endometriosis
GLP-1类似物，即艾塞那肽-4，通过中枢传递在去卵巢小鼠中改善了骨骼材料特性和强度。	Mermet, M.	PDF	N/A	The GLP-1 analogue, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice
# BioRxiv 2024-10-05 Papers

标题	作者	PDF链接	代码仓库	Title
乳腺癌分泌的因子通过抑制Rac1的激活，导致大鼠肌管萎缩并减少基础及胰岛素刺激的葡萄糖摄取。	Ali, M. S.	PDF	N/A	Breast cancer-secreted factors induce atrophy and reduce basal and insulinstimulated glucose uptake by inhibiting Rac1 activation in rat myotubes
在学习过程中，皮层L5树突中的未签名时间差误差	Schoenfeld, G.	PDF	N/A	Unsigned temporal difference errors in cortical L5 dendrites during learning
霍乱弧菌中的氨基糖苷耐药性涉及与tRNA修饰相关的翻译重编程，这种修饰涉及queuosine。	Fruchard, L.	PDF	N/A	Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification
Arche：一种用于微生物基因组片段功能高通量注释的高级灵活工具	Alonso-Reyes, D. G.	PDF	N/A	Arche: An Advanced Flexible Tool for High-throuput Annotation of Functions on Microbial Contigs
发现微型循环神经网络的认知策略	Ji-An, L.	PDF	N/A	Discovering Cognitive Strategies with Tiny Recurrent Neural Networks
通过多尺度模拟从头预测HIV-1 MPER抗体的特定磷脂复合物及膜结合	Maillie, C. A.	PDF	N/A	Ab initio prediction of specific phospholipid complexes and membrane association of HIV-1 MPER antibodies by multi-scale simulations
通过冷冻电镜解析人类MutSβ的多种高分辨率状态，揭示了ATP/ADP结合与异源双链DNA识别之间的相互作用	Lee, J.-H.	PDF	N/A	Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition
晚更新世小脑型人属纳莱迪人的意义建构行为：背景与进化意义	Fuentes, A.	PDF	N/A	Meaning-making behavior in a small-brained hominin, Homo naledi, from the late Pleistocene: contexts and evolutionary implications
上下文相关的多感官整合：机械感觉的鲁棒性能依赖于亮度	Sharma, V. P.	PDF	N/A	Context dependent multisensory integration: Mechanosensation depends on luminance for robust performance
分子伴侣的局部合成维持了神经元的蛋白质稳态	Alecki, C.	PDF	N/A	Localized synthesis of molecular chaperones sustains neuronal proteostasis
A型主动脉夹层在夹层前、夹层后及修复后的生物力学应力分析	Sun, C.	PDF	N/A	Biomechanical stress analysis of Type-A aortic dissection at pre-dissection, post-dissection, and post-repair states
基于图像的力学推断通过生物力学仿真实现	Vanslambrouck, M.	PDF	N/A	Image-based force inference by biomechanical simulation
基于三维催化域拓扑结构的原核DNA甲基转移酶新型分类系统	Samokhina, M.	PDF	N/A	A Novel Classification System for Prokaryotic DNA Methyltransferases Based on 3D Catalytic Domain Topology
量化非B DNA基序在癌症中作为非B负担标记的普遍性：使用NBBC	Xu, Q.	PDF	N/A	Quantifying the Prevalence of Non-B DNA Motifs as a Marker of Non-B Burden in Cancer using NBBC
植物细胞类型特异性顺式调控元件的演变	Yan, H.	PDF	N/A	Evolution of plant cell-type-specific cis-regulatory elements
β-1,2-葡聚糖酶的广泛分布：发现新的β-1,2-葡聚糖酶糖苷水解酶家族	Nakajima, M.	PDF	N/A	Extensive distribution of β-1,2-glucanases: finding of new glycoside hydrolase families of β-1,2-glucanases
微管力在LMNA心肌病中驱动核损伤	Amiad Pavlov, D.	PDF	N/A	Microtubule forces drive nuclear damage in LMNA cardiomyopathy
利用基因表达和机器学习预测与适应性相关的特征	Henry, G. A.	PDF	N/A	Predicting fitness related traits using gene expression and machine learning
树序列作为群体遗传推断的通用工具	Whitehouse, L. S.	PDF	N/A	Tree sequences as a general-purpose tool for population genetic inference
利用血清学调查优化人畜共患病原体的监测	Clancey, E.	PDF	N/A	Using serosurveys to optimize surveillance for zoonotic pathogens
帕金森病中α-突触核蛋白与NOD2相互作用及RIPK2激活驱动小胶质细胞介导的神经炎症	Seo, B. A.	PDF	N/A	Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease
Ramp协议：利用TeensyStep揭示个体在步行时对听觉节拍的差异	Zagala, A.	PDF	N/A	The Ramp protocol: Uncovering individual differences in walking to an auditory beat using TeensyStep
基因组简化：突变率和种群大小对基因组大小缩减的影响	Luiselli, J.	PDF	N/A	Genome streamlining: effect of mutation rate and population size on genome size reduction
果蝇哈姆雷特介导了生殖系统的上皮组织组装	Wang, H.	PDF	N/A	Drosophila Hamlet mediates epithelial tissue assembly of the reproductive system
MRAP2 修饰了黑皮质素-4受体的信号传导和寡聚状态	Sohail, I.	PDF	N/A	MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor
图对比学习作为高级单细胞RNA测序数据分析的多功能基础	Zhang, Z.	PDF	N/A	Graph Contrastive Learning as a Versatile Foundation for Advanced scRNA-seq Data Analysis
EpiCHAOS：一种用于量化单细胞数据中表观基因组异质性的指标	Kelly, K.	PDF	N/A	EpiCHAOS: a metric to quantify epigenomic heterogeneity in single-cell data
岩藻糖基转移酶2在过敏性气道高反应性和粘液阻塞中的需求	Hara, N.	PDF	N/A	Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction
注意错误会自适应地扭曲空间认知	Brissenden, J. A.	PDF	N/A	Errors of attention adaptively warp spatial cognition
通过随机连接的前馈网络中的树突计算来区分神经集合模式	Somashekar, B. P.	PDF	N/A	Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks
扩展任务开始时的元控制需求与其后续执行过程中的控制需求在类别上存在显著差异。	Akgur, B. F.	PDF	N/A	Meta-Control Demands at the Beginning of Extended Tasks are Categorically Different from Control Demands During Their Subsequent Execution
齿状回中功能失调的S1P/S1PR1信号传导导致慢性疼痛相关记忆障碍的易感性	Cui, M.	PDF	N/A	Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
一年内皮层厚度、表面积和脑体积的受试者内稳定性	Wang, M.-Y.	PDF	N/A	The within-subject stability of cortical thickness, surface area, and brain volumes across one year
单核转录组分析揭示了肌纤维XBP1在再生肌生成中的调控回路	Joshi, A. S.	PDF	N/A	Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis
AlphaFold3 晶状体中的非标准蛋白质 - 淀粉样蛋白案例研究	Wojciechowska, A. W.	PDF	N/A	Non-standard proteins in the lenses of AlphaFold3 - case study of amyloids
单细胞线粒体DNA突变分析中的假象误导了系统发育推断	Lareau, C. A.	PDF	N/A	Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference
完成对猿类基因组的完整测序	Yoo, D.	PDF	N/A	Complete sequencing of ape genomes
ImPaqT - 一个基于Golden Gate技术的斑马鱼转基因工具包	Hurst, S.	PDF	N/A	ImPaqT - A Golden Gate-based Toolkit for Zebrafish Transgenesis
发现不确定性：贝叶斯构成性人工神经网络	Linka, K.	PDF	N/A	Discovering uncertainty: Bayesian constitutive artificial neural networks
交配系统对多个属谱系分化的影响分析	Xu, K.	PDF	N/A	Analysis of the effects of mating systems on lineage diversification across multiple genera
在蜂鸟蛾中，飞行控制的并行路径整合反映了自然视觉线索的普遍性和相关性。	Stoeckl, A.	PDF	N/A	Integration of parallel pathways for flight control in a hawkmoth reflects prevalence and relevance of natural visual cues
两百年来环境变化中植物-真菌共生现象的日益普遍	Fowler, J. C.	PDF	N/A	Increasing prevalence of plant-fungal symbiosis across two centuries of environmental change
miR-21：一种在高脂饮食小鼠中延缓重度肝病和肝细胞癌的治疗靶点	Jagtap, U.	PDF	N/A	miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice
为什么我们有这么多兴奋性神经元？	Wang, Q.	PDF	N/A	Why do we have so many excitatory neurons?
Na+/K+-ATPase的生电性给高度活跃的尖峰细胞的计算带来了挑战。	Weerdmeester, L.	PDF	N/A	The electrogenicity of the Na+/K+-ATPase poses challenges for computation in highly active spiking cells
超快速多器官蛋白质组学揭示了药物疗效和毒性的组织特异性机制	Xiong, Y.	PDF	N/A	Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity
人类海马体中的正负视网膜拓扑编码	Angeli, P. A.	PDF	N/A	Positive and Negative Retinotopic Codes in the Human Hippocampus
内在无序蛋白质在其构象集合中可以表现出不同的聚合物行为。	Chakraborty, S.	PDF	N/A	Intrinsically disordered proteins can behave as different polymers across their conformational ensemble
针对神经纤毛蛋白-1增强黑色素瘤的免疫治疗：减少肿瘤进展及外周调节性T细胞介导的免疫抑制	Khamaru, S.	PDF	N/A	Targeting Neuropilin-1 to Enhance Immunotherapy in Melanoma: Reducing Tumour Progression and Peripheral Treg-Mediated Immunosuppression
海盗：掠夺AlphaFold预测以自动化蛋白质工程	Richardson, G.	PDF	N/A	PIRATE: Plundering AlphaFold Predictions to Automate Protein Engineering
一项针对具有形态多样解剖结构的人类主动脉CT图像的U-Net三维图像分割研究	Chen, J.	PDF	N/A	A 3D Image Segmentation Study of U-Net on CT Images of the Human Aorta with Morphologically Diverse Anatomy
血生物化学变化及由北西埃塞俄比亚贡达ELFORA屠宰场屠宰绵羊的捻转血矛线虫病引起的病变特征	Malede, B. A.	PDF	N/A	Haematobiochemical Alterations and Lesion Characterization Induced by Haemonchosis in Sheep Slaughtered at Gondar ELFORA Abattoir, North West Ethiopia
HBN-EEG：健康大脑网络（HBN）脑电图数据集的FAIR实现	Shirazi, S. Y.	PDF	N/A	HBN-EEG: The FAIR implementation of the Healthy Brain Network (HBN) electroencephalography dataset
研究早期儿童功能性和结构性脑网络架构、年龄与注意力技能之间的关系	Rokos, L.	PDF	N/A	Examining Relationships between Functional and Structural Brain Network Architecture, Age, and Attention Skills in Early Childhood
在分枝杆菌中破坏核黄素生物合成，确立了5-氨基-6-D-核糖胺尿嘧啶（5-A-RU）作为MAIT细胞激动剂的关键前体。	Chengalroyen, M. D.	PDF	N/A	Disruption of riboflavin biosynthesis in mycobacteria establishes 5-amino-6-D-ribitylaminouracil (5-A-RU) as key precursor of MAIT cell agonists
结构集合的弹性分析揭示了AAA+马达中手对手传递的能量基础	Mello, V. H.	PDF	N/A	Elastic analysis of structural ensemble reveals the energetic basis of hand-over-hand in a AAA+ motor
用于特诺河大西洋鲑（Salmo salar）种群复合体高效遗传种群鉴定的单核苷酸多态性基因分型面板	Johansson, H.	PDF	N/A	A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex
应用模块化异恶唑啉-β2,2-氨基酸基肽模拟折叠体作为研究tau错误折叠机制的化学模型系统。	Di Lorenzo, D.	PDF	N/A	Application of modular isoxazoline-β2,2-amino acid-based peptidomimetic foldamers as a chemical model system for studying the tau misfolding mechanism.
一个活性物质模型捕捉了形态发生过程中肌动蛋白-肌球蛋白振荡的空间动力学。	Mackay, E. D.	PDF	N/A	An active matter model captures the spatial dynamics of actomyosin oscillations during morphogenesis
一种用于分析谷物中淀粉颗粒大小分布的曲线拟合方法	McNelly, R.	PDF	N/A	A curve fitting method for analysing starch granule size distributions in cereals
FIP 1.0数据集：高分辨率注释图像时间序列，包含在六年中种植的4000个小麦地块	Roth, L.	PDF	N/A	The FIP 1.0 Data Set: Highly Resolved Annotated Image Time Series of 4,000 Wheat Plots Grown in Six Years
大麻和啤酒花中的FT样基因：性别特异性表达和拷贝数变异可能解释了开花时间的变异	Dowling, C. A.	PDF	N/A	FT-like genes in Cannabis and hops: sex specific expression and copy-number variation may explain flowering time variation
增强生长的非生物素依赖型酿酒酵母：构建乙酰辅酶A羧化酶旁路	Slanska, M.	PDF	N/A	Biotin-Independent Saccharomyces cerevisiae with Enhanced Growth: Engineering an Acetyl-CoA Carboxylase Bypass
运动想象超越想象中的动作，提升表现	Gippert, M.	PDF	N/A	Motor Imagery Enhances Performance Beyond the Imagined Action
利用多组儿科临床睡眠数据洞察神经发育：儿科睡眠回顾性分析（RASP）队列研究	Gong, N. N.	PDF	N/A	Leveraging clinical sleep data across multiple pediatric cohorts for insights into neurodevelopment: the Retrospective Analysis of Sleep in Pediatric (RASP) cohorts study
微生物生命树中质粒的缩放规律	Maddamsetti, R.	PDF	N/A	Scaling laws of plasmids across the microbial tree of life
微生物生命树中质粒的缩放规律	Maddamsetti, R.	PDF	N/A	Scaling laws of plasmids across the microbial tree of life
古菌信号网络——对产甲烷古菌Methanosarcina acetivorans中组氨酸激酶和响应调节蛋白结构与功能的新见解	Georgiev, N. F.	PDF	N/A	Archaeal signalling networks - new insights into the structure and function of histidine kinases and response regulators of the methanogenic archaeon Methanosarcina acetivorans
一个普遍存在且多样化的产甲烷群落推动了富营养化沿海沉积物中的微生物甲烷循环。	Wallenius, A. J.	PDF	N/A	A ubiquitous and diverse methanogenic community drives microbial methane cycling in eutrophic coastal sediments
黑素细胞分化和机械感觉受到不同细胞外基质蛋白的差异性调节	Luthold, C.	PDF	N/A	Melanocyte differentiation and mechanosensation are differentially modulated by distinct extracellular matrix proteins
组蛋白乙酰转移酶CBP的依赖催化与不依赖催化的功能促进先驱因子介导的合子基因组激活	Marsh, A. J.	PDF	N/A	Catalytic-dependent and independent functions of the histone acetyltransferase CBP promote pioneer factor-mediated zygotic genome activation
α-古巴烯对亚洲柑橘木虱Diaphorina citri具有强烈的驱避作用。	Magnani, R. F.	PDF	N/A	α-Copaene is a potent repellent against the Asian Citrus Psyllid Diaphorina citri
液滴微流控筛选用于工程化血管紧张素转换酶2（ACE2）的催化活性	Okal, E.	PDF	N/A	Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
利用无标签学习计算机视觉方法估算蜂鸟的拍翅频率	Bastidas-Rodriguez, M. X.	PDF	N/A	Estimating wingbeat frequency on hummingbirds by using a no-labeling learning computer vision approach
染色质结构的异质性驱动B细胞急性淋巴母细胞白血病中的核心调控通路	Sen, A.	PDF	N/A	Heterogeneity in chromatin structure drives core regulatory pathways in B-cell Acute Lymphoblastic Leukemia
通过植物中的激素运输实现对母体气候的跨代适应	Chen, X.	PDF	N/A	Trans-generational adaptation to maternal climate through hormone transport in plants
睡眠剥夺与饮食对生长、认知、炎症、氧化应激及组织组织学影响的评估	Usman, L. A.	PDF	N/A	ASSESSMENT OF THE IMPACT OF SLEEP DEPRIVATION AND DIET ON GROWTH, COGNITION, INFLAMMATION, OXIDATIVE STRESS, AND TISSUE HISTOLOGY
细菌和古菌中基因组重排的流行性与动态变化	Martinez-Gutierrez, C. A.	PDF	N/A	Prevalence and Dynamics of Genome Rearrangements in Bacteria and Archaea
倒立水母（Cassiopea）中乙酰胆碱能对睡眠的调控	Abrams, M. J.	PDF	N/A	Cholinergic regulation of sleep in the upside-down jellyfish Cassiopea
哺乳动物的胆汁酸化学感觉检测有助于物种和肠道微生物群的评估。	Haran, V.	PDF	N/A	Mammalian chemosensory bile acid detection supports species and gut microbiome evaluation
单突触腹侧被盖区谷氨酸投射至蓝斑，增强厌恶情绪处理。	Parker, K. E.	PDF	N/A	Monosynaptic ventral tegmental area glutamate projections to the locus coeruleus enhance aversive processing
通过强化学习，行为控制的大脑类神经动力学得以发展。	Codol, O.	PDF	N/A	Brain-like neural dynamics for behavioral control develop through reinforcement learning
支撑人类意识的大脑网络的皮层下中枢	Cambareri, M. K.	PDF	N/A	Subcortical Hubs of Brain Networks Sustaining Human Consciousness
运动皮层中言语思维的表征及其对言语神经假体的启示	Kunz, E. M.	PDF	N/A	Representation of Verbal Thought in Motor Cortex and Implications for Speech Neuroprostheses
Rho/Rok依赖的肌动肌球蛋白收缩性调控在三细胞连接处控制果蝇上皮通透性	Jacobs, T.	PDF	N/A	Rho/Rok-dependent regulation of actomyosin contractility at tricellular junctions controls epithelial permeability in Drosophila
运动单位间抑制性输入的异质分布是运动适应疼痛的关键机制	Hug, F.	PDF	N/A	Heterogeneous distribution of inhibitory inputs among motor units as a key mechanism for motor adaptations to pain
自动化、无压力且精确的鸣禽体重测量在神经科学实验中	Bonneh, Y.	PDF	N/A	Automated, Stress-Free, and Precise Measurement of Songbird Weight in Neuroscience Experiments
神经群体动态的动态模型	Hao, H.	PDF	N/A	Dynamic Models of Neural Population Dynamics
用于双光子亚细胞钙成像的预处理工具箱	Jiang, A.	PDF	N/A	A preprocessing toolbox for 2-photon subcellular calcium imaging
研究健康和受损的人三叉神经中与神经性疼痛相关的细胞和分子变化	Morchio, M.	PDF	N/A	Investigation of cellular and molecular changes linked with neuropathic pain in healthy and injured human trigeminal nerves
光遗传学激活丘脑网状核对小鼠睡眠结构的影响	Arai, M.	PDF	N/A	Impact of Optogenetic Activation of the Thalamic Reticular Nucleus on Sleep Architecture in Mice
上丘投射驱动多巴胺神经元活动和运动，但不驱动价值	Poisson, C. L.	PDF	N/A	Superior colliculus projections drive dopamine neuron activity and movement but not value
针对C9ORF72中致病性正义重复RNA的反义寡核苷酸能够抑制依赖反义链的二肽重复蛋白的产生，这些蛋白与ALS/FTD相关。	Gu, Y.	PDF	N/A	Antisense oligonucleotide targeting pathogenic sense repeat RNA in C9ORF72 suppresses production of antisense-dependent dipeptide repeat proteins implicated in ALS/FTD
早期听觉和成年后的交配经历与鸣禽身份相互作用，塑造了雌性斑胸草雀对鸣唱的神经反应。	Catalano, I.	PDF	N/A	Early auditory and adult mating experiences interact with singer identity to shape neural responses to song in female zebra finches
悬浮组织开放微流控图案化技术（STOMP）	Haack, A. J.	PDF	N/A	Suspended Tissue Open Microfluidic Patterning (STOMP)
生物膜形成的电生成动力学：枯草芽孢杆菌中基因表达与电化学活性之间的关联	Yavarinasab, A.	PDF	N/A	Electrogenic Dynamics of Biofilm Formation: Correlation Between Genetic Expression and Electrochemical Activity in Bacillus subtilis
磷酸化对PRC1微管交联作用的影响探究	Tai, E.	PDF	N/A	Insights into the role of phosphorylation on microtubule crosslinking by PRC1
在临床扫描仪上使用神经突交换成像（NEXI）绘制的人类灰质微结构图	Uhl, Q.	PDF	N/A	Human gray matter microstructure mapped using Neurite Exchange Imaging (NEXI) on a clinical scanner
人类和小鼠的Kabuki综合征模型揭示了抑制性突触发育的增加。	Knopp, J.	PDF	N/A	Human and Mouse Models for Kabuki Syndrome Reveal Increase in Inhibitory Synapse Development.
海马长轴功能特化的成年寿命效应	Bowman, C.	PDF	N/A	Adult lifespan effects on functional specialization along the hippocampal long axis
谨慎标记 - 蛋白质标记如何影响凝聚物的形成	D/"orner, K.	PDF	N/A	Tag with Caution - How protein tagging influences the formation of condensates
Siglec-F缺乏可预防博来霉素诱导的急性肺损伤后的纤维化	Orlov, M.	PDF	N/A	Siglec-F Deficiency Prevents Fibrosis After Bleomycin-Induced Acute Lung Injury
跨物种保护表明，溶组织内阿米巴的吞噬作用通过转移补体激活的负调控因子实现了对补体的抵抗。	Ruyechan, M.	PDF	N/A	Cross-species protection suggests Entamoeba histolytica trogocytosis enables complement resistance through the transfer of negative regulators of complement activation
肠道细菌编码的还原酶能够生物转化类固醇激素	Arp, G.	PDF	N/A	Gut Bacteria Encode Reductases that Biotransform Steroid Hormones
G3BP应激颗粒蛋白强化了整合应激反应的翻译程序	Smith, J.	PDF	N/A	The G3BP Stress-Granule Proteins Reinforce the Translation Program of the Integrated Stress Response
揭示果蝇（Drosophila melanogaster）现有遗传变异中对寿命具有显著效应的位点及上位性	van den Heuvel, J.	PDF	N/A	Uncovering large effect loci and epistasis for lifespan in standing genetic variation in the fruit fly Drosophila melanogaster
LEU2和BAP2的共致死性依赖于碳源，并且在酿酒酵母中通过删除BUL1得以克服。	S, M.	PDF	N/A	Co-lethality of LEU2 and BAP2 is carbon source dependent and is overcome by BUL1 deletion in Saccharomyces cerevisiae
定义基因组范围分析和群体数据库的串联重复目录及变异簇	Weisburd, B.	PDF	N/A	Defining a tandem repeat catalog and variation clusters for genome-wide analyses and population databases
内在分子标识符能够在单细胞测序中实现稳健的分子计数	Fontanez, K.	PDF	N/A	Intrinsic molecular identifiers enable robust molecular counting in single-cell sequencing
氨基-罗卡拉特增强eIF4A1 RNA夹合的结构基础	Conley, J. F.	PDF	N/A	Structural Basis for the Improved RNA-Clamping of Amidino-Rocaglates to eIF4A1
Ixochymostatin，一种来自Ixodes scapularis的类胰蛋白酶抑制剂（TIL）蛋白，能够抑制糜蛋白酶并损害血管通透性。	Almeida Martins, L.	PDF	N/A	Ixochymostatin, a trypsin inhibitor-like (TIL) protein from Ixodes scapularis, inhibits chymase and impairs vascular permeability
改进基于扩散的蛋白质骨架生成与全局几何感知潜在编码	Zhang, Y.	PDF	N/A	Improving diffusion-based protein backbone generation with global-geometry-aware latent encoding
FunCoup Cytoscape应用程序：多物种网络分析与可视化	Buzzao, D.	PDF	N/A	The FunCoup Cytoscape App: multi-species network analysis and visualization
仿生和等离子体膜囊泡的形状分析	Kudawla, R.	PDF	N/A	Shape analysis of biomimetic and plasma membrane vesicles
拉伸诱导肌球蛋白进入横向肌动蛋白环，稳定轴突大货物运输	Rahman, N.	PDF	N/A	Stretch-induced recruitment of myosin into transversal actin rings stabilizes axonal large cargo transport
朝向精确、力场无关的内在无序蛋白质构象集合	Borthakur, K.	PDF	N/A	Towards accurate, force field independent conformational ensembles of intrinsically disordered proteins
通过共价别构分子胶抑制NRF2依赖的癌症生长	Roy, N.	PDF	N/A	Suppression of NRF2-dependent cancer growth by a covalent allosteric molecular glue
一种用于体外常温多脏器灌注平台开发的迭代设计方法	van Leeuwen, L. L.	PDF	N/A	An iterative design approach to development of an ex-vivo normothermic multivisceral perfusion platform
全面测序哮喘诱导下肺神经免疫景观	McSwiggin, H.	PDF	N/A	Comprehensive sequencing of the lung neuroimmune landscape in response to asthmatic induction
C-反应蛋白通过激活补体系统，在肝脏中强力清除血液中的细菌	Chen, D.	PDF	N/A	C-Reactive Protein Drives Potent Clearance of Blood Bacteria in the Liver by Activating the Complement System
通过使用大肠杆菌作为模型微生物，区分纳米铜和离子铜的抗菌机制	Jose, G. P.	PDF	N/A	Differentiating the mechanism of antibacterial activities of nano and ionic copper by using Escherichia coli as a model microorganism
测试被子植物和苔藓物种生命阶段间冲突的基因组足迹	Yuan, M.	PDF	N/A	Testing for the genomic footprint of conflict between life stages in an angiosperm and a moss species
种群大小对适应温度波动的影响	Räsänen, E.	PDF	N/A	The effect of population size on adaptation to fluctuating temperatures
进化史中长期的营养不良会增强老年时期的病原体易感性。	Sarkar, S.	PDF	N/A	Evolutionary history with chronic malnutrition enhances pathogen susceptibility at older ages
酵母氨基酸感应SEAC-EGOC超复合体的结构与功能	Tafur, L.	PDF	N/A	Structure and function of the yeast amino acid-sensing SEAC-EGOC supercomplex
池塘伙伴：一种基于PageRank的池化方法，用于深度学习中鲁棒的蛋白质序列表示	TARTICI, A.	PDF	N/A	Pool PaRTI: A PageRank-based Pooling Method for Robust Protein Sequence Representation in Deep Learning
人类无机磷酸盐出口蛋白XPR1的运输与InsP8激活机制	Zhu, Q.	PDF	N/A	Transport and InsP8 activation mechanisms of the human inorganic phosphate exporter XPR1
ADT-1004：一种口服生物可利用的、选择性泛RAS抑制剂，用于胰腺导管腺癌的首创药物	El-Rayes, B. N.	PDF	N/A	ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma
阿拉伯胶（阿拉伯胶树）以性别特异性和剂量依赖性的方式增强斑马鱼的繁殖并调节其微生物-肠道-大脑轴	Abi Assaf, J.	PDF	N/A	Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbiota-gut-brain axis of zebrafish in a sex-specific and dosage-dependent manner
深度挖掘人类抗体库可识别出频繁且免疫遗传多样化的CDRH3拓扑结构，这些结构可通过疫苗接种进行靶向。	Habib, R.	PDF	N/A	Deep Mining of the Human Antibody Repertoire Identifies Frequent and Immunogenetically Diverse CDRH3 Topologies Targetable by Vaccination
YY1的N端调节DNA和RNA对锌指结构域以及一个意外的核酸结合结构域的结合亲和力。	Elias, J.	PDF	N/A	The N-terminus of YY1 regulates DNA and RNA binding affinity for both the zinc-fingers and an unexpected nucleic acid binding domain
温度诱导的膜运输驱动抗体向大脑的递送	Du, F.	PDF	N/A	Temperature-induced membrane trafficking drives antibody delivery to the brain
核孔蛋白出口复合体的结构基础：RanBP2、SUMO1-RanGAP1、E2 Ubc9、Crm1与Ran GTPase之间的相互作用	Baytshtok, V.	PDF	N/A	Structural basis for a nucleoporin exportin complex between RanBP2, SUMO1-RanGAP1, the E2 Ubc9, Crm1 and the Ran GTPase
# BioRxiv 2024-10-04 Papers

标题	作者	PDF链接	代码仓库	Title
如何利用转录组数据进行癌症细胞治疗诱导抗性的博弈论建模？基于患者来源的胶质母细胞瘤类器官的案例研究	Spekking, L.	PDF	N/A	How to use transcriptomic data for game-theoretic modeling of treatment-induced resistance in cancer cells? A case study in patient-derived glioblastoma organoids
树突生长和突触组织受活动无关的线索和局部活动依赖性可塑性的调控。	Kirchner, J. H.	PDF	N/A	Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity
依赖于SAM的病毒MTase抑制剂：汉黄芩素和咖啡酸苯乙酯，对登革热MTase的结构洞察	Bhutkar, M.	PDF	N/A	SAM-dependent viral MTase inhibitors: herbacetin and caffeic acid phenethyl ester, structural insights into dengue MTase
控制有限感知决策	Castineiras de Saa, J. R.	PDF	N/A	Control Limited Perceptual Decision Making
新皮层电路振荡动力学的功能作用：一种计算视角	Effenberger, F.	PDF	N/A	The functional role of oscillatory dynamics of neocortical circuits: a computational perspective
基底外侧杏仁核振荡在生物物理模型中实现恐惧学习	Cattani, A.	PDF	N/A	Basolateral amygdala oscillations enable fear learning in a biophysical model
液-液界面限制能够再现体内中性粒细胞的形变，并引发基于囊泡的迁移。	Schrope, J. H.	PDF	N/A	Confinement by liquid-liquid interface replicates in vivo neutrophil deformations and elicits bleb based migration
大规模皮层网络以结构化的循环方式组织。	van Es, M. W. J.	PDF	N/A	Large-scale cortical networks are organized in structured cycles
通过脑桥网状结构进行运动控制的皮层-皮层下回路	Bosz, E.	PDF	N/A	A cortico-subcortical loop for motor control via the pontine reticular formation
对小鼠集合淋巴管的细胞成分进行表征，结果显示淋巴肌肉细胞是调节淋巴收缩的固有起搏细胞。	Zawieja, S. D.	PDF	N/A	Characterization of the cellular components of mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells regulating lymphatic contractions
NPYR介导的调制是经验依赖性、性二态学习的基础	Peedikayil-Kurien, S.	PDF	N/A	Modulation by NPYR underlies experience-dependent, sexually dimorphic learning
胰岛素和运动诱导的人类骨骼肌磷酸蛋白质组学研究揭示REPS1为肌肉葡萄糖摄取的新调控因子	Kjaergaard, J.	PDF	N/A	Insulin and Exercise-induced Phosphoproteomics of Human Skeletal Muscle Identify REPS1 as a New Regulator of Muscle Glucose Uptake
撤回：飞蝗在躲避碰撞行为中的飞行肌协调与身体方向变化	Manchester, C. W.	PDF	N/A	WITHDRAWN: Flight muscle coordination and body orientation changes of Locusta migratoria during collision avoidance behaviour
利用大型语言模型揭示人脑中的多层次和多模态语义表征	Nakagi, Y.	PDF	N/A	Unveiling Multi-level and Multi-modal Semantic Representations in the Human Brain using Large Language Models
人类在自然噪声中对语音识别的敏感性，其基础在于中等水平声音统计的干扰。	Clonan, A. C.	PDF	N/A	Interference of mid-level sound statistics underlie human speech recognition sensitivity in natural noise
ADAMTS7促进动脉粥样硬化中的平滑肌泡沫细胞扩张	Chung, A.	PDF	N/A	ADAMTS7 Promotes Smooth Muscle Foam Cell Expansion in Atherosclerosis
肝细胞RIPK1在代谢挑战期间维持肝脏稳态的作用	Zhang, W.	PDF	N/A	Role of Hepatocyte RIPK1 in Maintaining Liver Homeostasis during Metabolic Challenges
多媒体：微生物组数据的多元中介分析	Jiang, H.	PDF	N/A	multimedia: Multimodal Mediation Analysis of Microbiome Data
一项全基因组CRISPR筛选揭示了内体成熟蛋白WDR91作为黑色素瘤中有效ASO活性的促进因子	Menchon, G.	PDF	N/A	A Genome-wide CRISPR screen unveils the endosomal maturation protein WDR91 as a promoter of productive ASO activity in melanoma
侧嗅皮层功能障碍在阿尔茨海默病小鼠中的表现	Raghuraman, R.	PDF	N/A	Lateral Entorhinal Cortex Dysfunction in Alzheimer's Disease Mice
时空变换器用于解码神经运动控制	Candelori, B.	PDF	N/A	Spatio-temporal transformers for decoding neural movement control
双层图学习揭示了乳腺癌多重数字病理学中与预后相关的肿瘤微环境模式	Wang, Z.	PDF	N/A	Bi-level Graph Learning Unveils Prognosis-Relevant Tumor Microenvironment Patterns in Breast Multiplexed Digital Pathology
硅藻光系统I超复合物中岩藻黄素叶绿素a/c结合蛋白分子组装的结构基础	Kato, K.	PDF	N/A	Structural basis for molecular assembly of fucoxanthin chlorophyll a/c-binding proteins in a diatom photosystem I supercomplex
青少年时期，大血管血流与微血管脑血管反应性在区域上是相互关联的。	Zvolanek, K. M.	PDF	N/A	Macrovascular blood flow and microvascular cerebrovascular reactivity are regionally coupled in adolescence
小鼠感染拉科罗斯病毒后，中和抗体、细胞因子和趋化因子的年龄特异性动态变化	Alatrash, R.	PDF	N/A	Age-specific dynamics of neutralizing antibodies, cytokines, and chemokines in response to La Crosse virus infection in mice
胎盘疟疾引发独特的甲基化模式，与胎儿生长受限相关	Ozarslan, N.	PDF	N/A	Placental Malaria Induces a Unique Methylation Profile Associated with Fetal Growth Restriction
基于模型的力信号反卷积以估计在低、中和高力等长收缩下的运动单位抽搐参数	Rohlen, R.	PDF	N/A	Model-based deconvolution of a force signal to estimate motor unit twitch parameters under low, moderate and high force isometric contractions
线粒体的动态变化支持了小胶质细胞表型的灵活性	Espinoza, K.	PDF	N/A	Dynamic changes in mitochondria support phenotypic flexibility of microglia
元控制需求会抑制认知控制区域	Akgur, B. F.	PDF	N/A	Meta-Control Demands Deactivate Cognitive-Control Regions
响应红光的Cre重组酶用于细菌的光遗传学	Jafarbeglou, F.	PDF	N/A	Red light responsive Cre recombinase for bacterial optogenetics
蜂鸟传粉和自花传粉的猴面花（Mimulus）物种之间花部性状分化的遗传结构	Chen, H.	PDF	N/A	The genetic architecture of floral trait divergence between hummingbird- and self-pollinated monkeyflower (Mimulus) species
不同的多巴胺能脉冲时序依赖可塑性规则适合不同的功能角色	Sosis, B.	PDF	N/A	Distinct dopaminergic spike-timing-dependent plasticity rules are suited to different functional roles
左半球对元音的衰减处理预测了自闭症儿童在噪音环境中的语音感知缺陷	Fadeev, K. A.	PDF	N/A	Attenuated processing of vowels in the left hemisphere predicts speech-in-noise perception deficit in children with autism
非遍历性和辛普森悖论在认知控制神经认知动力学中的体现	Mistry, P. K.	PDF	N/A	Nonergodicity and Simpson's paradox in neurocognitive dynamics of cognitive control
PA28γ通过提升线粒体功能，促进肿瘤的恶性进展，这一过程依赖于C1QBP。	Wang, J.	PDF	N/A	PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
在坦桑尼亚南部的一个下放野生动物管理区内，围绕授权渔业定居点建立了一个有效的社区保护模式。	Duggan, L. M.	PDF	N/A	An effective model for community-based conservation around authorized fishing settlements inside a devolved Wildlife Management Area in southern Tanzania
通过Cre/loxP系统快速体外组装并转移DNA片段至JCVI-syn3B最小合成细菌基因组的方法	Uenoyama, A.	PDF	N/A	Rapid in vitro method to assemble and transfer DNA fragments into the JCVI-syn3B minimal synthetic bacterial genome through Cre/loxP system
儿童中枢神经系统肿瘤中异常剪接的特征分析揭示CLK1为候选致癌依赖基因	Naqvi, A. S.	PDF	N/A	Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency
局部横向连接足以在深度神经网络中复制类似皮层的拓扑组织	Qian, X.	PDF	N/A	Local lateral connectivity is sufficient for replicating cortex-like topographical organization in deep neural networks
循环网络中的状态表示学习：随机反馈和生物约束的力量	Tsurumi, T.	PDF	N/A	Learning of state representation in recurrent network: the power of random feedback and biological constraints
CRISP：相关性优化图像分割过程	Briggs, J.	PDF	N/A	CRISP: Correlation-Refined Image Segmentation Process
确定抗生素的脱靶活性以及线粒体中新颖的翻译起始位点	Marks, J.	PDF	N/A	Determining the off-target activity of antibiotics and novel translation initiation sites in mitochondria
揭示CRBN分子胶水隐藏的相互作用组：化学蛋白质组学研究	Baek, K.	PDF	N/A	Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics
性发育、生长发育和营养依赖的大西洋鲑鱼主要成熟年龄基因表达	Asheim, E. R.	PDF	N/A	Sex-, development-, and nutrition-dependent expression of a major age-at-maturity gene in Atlantic salmon
量化生物研究中条形图的数据失真	Lin, T.-J.	PDF	N/A	Quantifying Data Distortion in Bar Graphs in Biological Research
光质信号的整合调控了幼苗建立过程中ABA含量和气孔运动	Gustavsson, M.	PDF	N/A	Integration of light quality signals regulates ABA abundance and stomatal movements during seedling establishment
特定的序列特征会导致在检测多态性转座子插入时出现偏差。	Verneret, M.	PDF	N/A	Particular sequence characteristics induce bias in the detection of polymorphic transposable element insertions
电磁刺激各向异性水凝胶用于引导神经形态发生	Jensen, B. N.	PDF	N/A	Electromagnetic Stimulated Anisotropic Hydrogels for Guided Neuronal Morphogenesis
CXXC指蛋白1与FOXP3相互作用，以稳定调节性T细胞的内稳态和抑制功能	Meng, X.	PDF	N/A	CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells
鉴定与先天性心脏病中临床报告的CNV相关的长链非编码RNA候选疾病基因	Penaloza, J. S.	PDF	N/A	Identification of Long Non-coding RNA Candidate Disease Genes Associated with Clinically Reported CNVs in Congenital Heart Disease
与满江红共培养对整株水稻代谢组的影响超越了传统无机氮肥的作用	Consorti, E.	PDF	N/A	Co-cultivation with Azolla affects the metabolome of whole rice plant beyond canonical inorganic nitrogen fertilization
发育中的人类肺部空间解析蓝图揭示了一种由WNT驱动微环境调控的基底细胞群体	Hsu, P. P.	PDF	N/A	A spatially-resolved blueprint of the developing human lung reveals a basal cell population regulated by a WNT-driven niche
一个针对环境16S rRNA牛津纳米孔测序数据分析的优化参考数据库	Philip, M.	PDF	N/A	A Targeted Reference Database for Improved Analysis of Environmental 16S rRNA Oxford Nanopore Sequencing Data
在重构系统中20种氨酰-tRNA合成酶的可持续再生：迈向自合成人工系统的研究	Hagino, K.	PDF	N/A	Sustainable Regeneration of 20 Aminoacyl-tRNA Synthetases in a Reconstituted System Toward Self-Synthesizing Artificial Systems
拟南芥RNA结合蛋白SGS3被招募到染色质重塑因子CHR11上，以促进从蛋白质编码基因中产生小干扰RNA（siRNA）。	Elmayan, T.	PDF	N/A	The Arabidopsis RNA-binding protein SGS3 is recruited to the chromatin remodeler CHR11 to promote siRNA production from protein-coding genes
早期转移过程中力学生物学信号对骨细胞的调控驱动后续的骨质溶解：一个计算力学调控框架的预测	Verbruggen, A. S. K.	PDF	N/A	Mechanobiological cues to bone cells during early metastasis drive later osteolysis: a computational mechanoregulation framework prediction
常规经颅直流电刺激（tDCS）和高清晰度经颅直流电刺激（HD-tDCS）对小脑的偏移镇痛作用的差异效应	O'Connor, N.	PDF	N/A	Differential effects of conventional transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) of the cerebellum on offset analgesia
Meta2DB：为健康状态预测而精选的鸟枪法宏基因组特征集及元数据	Kok, C. R.	PDF	N/A	Meta2DB: Curated Shotgun Metagenomic Feature Sets and Metadata for Health State Prediction
单脉冲和成对脉冲经颅磁刺激在人类近中央皮质中激活了空间上不同的皮质运动表征	Madsen, M. A. J.	PDF	N/A	Single and paired TMS pulses engage spatially distinct corticomotor representations in human pericentral cortex
口服暴露于牛奶巴氏灭菌的HPAI H5N1对小鼠免疫反应和死亡率的影响	Brigleb, P. H.	PDF	N/A	Effects of Oral Exposure to HPAI H5N1 Pasteurized in Milk on Immune Response and Mortality in Mice
一种利用生物层干涉技术测量纳米抗体结合动力学及基于竞争的表位定位的有效方法	Bates, T. A.	PDF	N/A	An effective method of measuring nanobody binding kinetics and competition-based epitope mapping using biolayer interferometry
氧化应激与心血管疾病中钙调节蛋白关联的数据驱动性见解。	Panday, N.	PDF	N/A	Data-driven insights into the association between oxidative stress and calcium-regulating proteins in cardiovascular disease.
三维重建技术实现了高效的大规模表型分析和叶序的定量遗传学研究。	Davis, J. M.	PDF	N/A	3D Reconstruction Enables High-Throughput Phenotyping and Quantitative Genetic Analysis of Phyllotaxy
通过拓扑高阶功能连接揭示精神分裂症中的整合-分离失衡	Li, Q.	PDF	N/A	Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity
决策信心与结果变异性最佳调控超参数设置的不同方面	Desender, K.	PDF	N/A	Decision Confidence and Outcome Variability Optimally Regulate Separate Aspects of Hyperparameter Setting
双语能力调节学龄前儿童执行功能发展：一项初步研究	Sade, S.	PDF	N/A	Bilingualism Modulates Executive Function Development in Pre-School Aged Children: A Preliminary Study
欧洲积极自然未来的叙事	D'Alessio, A.	PDF	N/A	Narratives for positive nature futures in Europe
分泌的精胺合成酶揭示了PGC1a诱导的前列腺癌生长抑制的旁分泌作用	Schaub Clarigue, A.	PDF	N/A	Secreted spermidine synthase reveals a paracrine role for PGC1a-induced growth suppression in prostate cancer
自愿的预扫视注意和非自愿的外源性注意对对比度外观的相同双向调制	Zhang, T.	PDF	N/A	Same bi-directional modulation of contrast appearance for voluntary presaccadic attention and involuntary exogenous attention
前额叶皮层的不规则神经兴奋可以抵消与年龄相关的海马体θ活动在空间记忆维持中的减少。	Park, S.-E.	PDF	N/A	Aperiodic neural excitation of the prefrontal cortex offsets age-related decrease in hippocampal theta activity for spatial memory maintenance
糖原合酶激酶-3对于调节性T细胞的发育和功能至关重要。	Kandasamy, M.	PDF	N/A	Glycogen synthase kinase-3 is essential for Treg development and function
保守的染色质调控因子控制秀丽隐杆线虫对胞内病原体的转录免疫反应	Tecle, E.	PDF	N/A	Conserved chromatin regulators control the transcriptional immune response to intracellular pathogens in Caenorhabditis elegans
在分枝杆菌中破坏核黄素生物合成，确立了5-氨基-6-D-核糖氨基尿嘧啶（5-A-RU）作为MAIT细胞激动剂的关键前体。	Chengalroyen, M. D.	PDF	N/A	Disruption of riboflavin biosynthesis in mycobacteria establishes 5-amino-6-D-ribitylaminouracil (5-A-RU) as key precursor of MAIT cell agonists
新型嵌套基因Aff3ir的破坏介导了小鼠中紊乱血流诱导的动脉粥样硬化	He, S.	PDF	N/A	Disruption of the Novel Nested Gene Aff3ir Mediates Disturbed Flow-Induced Atherosclerosis in Mice
拟南芥花分生组织中生长素信号传导中的随机基因表达	Kong, S.	PDF	N/A	Stochastic Gene Expression in Auxin Signaling in the Floral Meristem of Arabidopsis thaliana
减少覆盖范围的空间异质性可以提高狗类狂犬病疫苗接种的有效性。	Ferguson, E.	PDF	N/A	Reducing spatial heterogeneity in coverage improves the effectiveness of dog vaccination against rabies
元生物中g型溶菌酶的进化：对免疫和消化适应性的见解	Moroz, L. L.	PDF	N/A	Evolution of g-Type Lysozymes in Metazoa: Insights into Immunity and Digestive Adaptations
基于系统发育的模拟表明，在真核生物起源期间，未采样的分支对基因流推断的影响较小。	Bernabeu, M.	PDF	N/A	Phylogeny-aware simulations suggest a low impact of unsampled lineages in the inference of gene flow during eukaryogenesis
亚端粒特异性凝聚染色质受三种不同的组蛋白修饰调控	Osaki, M.	PDF	N/A	Subtelomere-specific condensed chromatin is regulated by three different histone modifications
人群数据中极端离群RNA表达模式揭示了在个体子集中偶发性基因过度激活及其共调控模块	Xie, C.	PDF	N/A	Patterns of extreme outlier RNA expression in population data reveal sporadic over-activation of genes with co-regulated modules in subsets of individuals
利用等位基因失衡数量性状位点模型探究顺式作用基因调控的极限	Seoighe, C.	PDF	N/A	Probing the limits of cis-acting gene regulation using a model of allelic imbalance quantitative trait loci
三维机械限制指导肌肉干细胞的命运和功能	Park, G.	PDF	N/A	3D mechanical confinement directs muscle stem cell fate and function
计算设计与评估用于可扩展邻近蛋白质组学的最佳诱饵集	Kasmaeifar, V.	PDF	N/A	Computational design and evaluation of optimal bait sets for scalable proximity proteomics
可展开治疗性抗体的计算设计：高效遍历结合剂景观及逃逸突变的挽救	Dreyer, F. A.	PDF	N/A	Computational design of developable therapeutic antibodies: efficient traversal of binder landscapes and rescue of escape mutations
更多细胞，高倍多重单细胞数据中的更多二聚体	Howitt, G.	PDF	N/A	More cells, more doublets in highly multiplexed single-cell data
应激途径的镶嵌调控奠定了衰老细胞异质性的基础	Avelar, R. A.	PDF	N/A	Mosaic Regulation of Stress Pathways Underlies Senescent Cell Heterogeneity
增强的弱监督千兆像素WSI训练池化技术提高了分类和病变定位效果	Chen, C.-C.	PDF	N/A	Enhanced Pooling for Weakly Supervised Gigapixel WSI Training Improves Classification and Lesion Localization
EGDiff：一种实验引导的扩散模型，用于蛋白质构象系综生成	Liu, Y.	PDF	N/A	EGDiff: An Experiment-Guided Diffusion model for protein conformational ensemble generation
对福尔马林固定石蜡包埋（FFPE）组织进行单细胞RNA测序，在乳腺癌中鉴定出多纤毛细胞	Gonzalez-Martinez, S.	PDF	N/A	Single-cell RNA sequencing on formalin-fixed and paraffin-embedded (FFPE) tissue identified multi-ciliary cells in breast cancer
RUVBL1和RUVBL2是神经母细胞瘤中可药物干预的MYCN调节因子。	Siaw, J. T.	PDF	N/A	RUVBL1 and RUVBL2 are druggable MYCN regulators in neuroblastoma.
源自患者的胶质母细胞瘤类器官作为实时模型，用于评估临床CAR-T细胞疗法的反应	Logun, M.	PDF	N/A	Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy
真正的海洋昆虫——奥氏棘虱（Echinophthirius horridus von Olfers, 1816）（虱目：棘虱科）的独特体表形态	White, T.	PDF	N/A	Unique cuticular morphology of a truly marine insect, Echinophthirius horridus von Olfers, 1816 (Phthiraptera: Echinophthiriidae)
肌肉特异性Keap1缺失增强了肌肉力量生成，但并未能阻止小鼠因不活动导致的肌肉萎缩。	Miranda, E. R.	PDF	N/A	Muscle-specific Keap1 deletion enhances force production but does not prevent inactivity-induced muscle atrophy in mice
一项多组学普查揭示了与肥胖相关的微小RNA miR-let-7作为脂肪线粒体功能障碍和代际代谢衰退的新型引发因素。	Huang, C.	PDF	N/A	A multi-omics census reveals obesity-associated microRNA miR-let-7 as novel instigator of adipose mitochondrial dysfunction and of intergenerational metabolic decline.
H+ 驱动超快根对根响应伤口	Ducla, J.	PDF	N/A	H+ drives ultra-fast root-to-root responses to wounding
通过MPK6磷酸化实现对MYC2的靶向降解揭示了JA信号传导的机制和意义	Han, K.-H.	PDF	N/A	Targeted Degradation of MYC2 through MPK6 Phosphorylation Reveals Mechanisms and Implications for JA Signaling
扩展的底物范围交叉手性连接法实现了长L-RNA的高效合成	Han, X.	PDF	N/A	An Expanded Substrate Scope for Cross-Chiral Ligation Enables Efficient Synthesis of Long L-RNAs
基于计算模型的细菌二硝基甲苯传感器设计	Bahiri Elitzur, S.	PDF	N/A	Design of bacterial DNT sensors based on computational models
噪声生物系统的数据驱动模型发现与模型选择	Wu, X.	PDF	N/A	Data-driven model discovery and model selection for noisy biological systems
自噬、泛素蛋白酶体系统和MAPK通路控制突触生长的温度依赖性。	De Leon, K.	PDF	N/A	Autophagy, the Ubiquitin proteasome system, and the MAPK pathway control the temperature dependence of synaptic growth.
在灵长类动物腹侧前运动皮层中时间感知期间的情境神经动力学	Diaz, H.	PDF	N/A	Contextual Neural Dynamics During Time Perception in Primate Ventral Premotor Cortex
使用合成轴突形态生成全脑连接组	Petkantchin, R.	PDF	N/A	Generating brain-wide connectome using synthetic axonal morphologies
猕猴扣带皮层中的冲突神经元	Corrigan, B. W.	PDF	N/A	Conflict neurons in cingulate cortex of macaques
阿尔茨海默病中与脑血管损伤和β-淀粉样蛋白并行的神经炎症通路	Rizvi, B.	PDF	N/A	Parallel neuroinflammatory pathways to cerebrovascular injury and amyloid-beta in Alzheimer's disease
多感官伽马刺激增强了成年神经发生，并在唐氏综合症小鼠模型中改善了认知功能。	Islam, M. R.	PDF	N/A	Multisensory gamma stimulation enhances adult neurogenesis and improves cognitive function in a mouse model of Down syndrome
一项关于脊髓损伤即时后果的药理学调控的电生理学研究揭示了TRPV4拮抗作用的关键作用。	Mohammadshirazi, A.	PDF	N/A	An electrophysiological study about the pharmacological manipulation of the immediate consequences of a spinal trauma reveals a crucial role for TRPV4 antagonism.
秀丽隐杆线虫连接组中的双侧对称性与不对称性：基于冗余度测量的图论分析	Kim, P. S.	PDF	N/A	Bilateral Symmetry and Asymmetry in the C. elegans Connectome: A Graph-Theoretic Analysis based on Redundancy Measures
神经运动生成的背后空间和网络原理	Komi, S.	PDF	N/A	Spatial and network principles behind neural generation of locomotion
前视区谷氨酸能神经元对快速眼动睡眠起始和稳态的调控	Mondino, A.	PDF	N/A	Regulation of REM Sleep Onset and Homeostasis by Preoptic Glutamatergic Neurons
达成一致：fMRI-超扫描揭示了双人组在心理状态空间中探索以协调意见。	Speer, S. P.	PDF	N/A	Finding Agreement: fMRI-hyperscanning reveals that dyads explore in mental state space to align opinions.
APOE通过抑制中性粒细胞胞外陷阱的产生，保护机体免受结核分枝杆菌严重感染。	Liu, D.	PDF	N/A	APOE Protects Against Severe Infection with Mycobacterium tuberculosis by Restraining Production of Neutrophil Extracellular Traps
肺部CD4+驻留记忆T细胞利用气道分泌细胞来刺激和调节中性粒细胞性过敏性气道疾病。	Ravi, V. R.	PDF	N/A	Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate neutrophilic allergic airways disease.
针对丙型肝炎病毒E1E2包膜糖蛋白的双特异性抗体	Radic, L.	PDF	N/A	Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein
普遍规律支配着质粒拷贝数	Ramiro-Martinez, P.	PDF	N/A	Universal rules govern plasmid copy number
加热处理改变了野生蓝莓土壤中细菌多样性和组成的时序动态。	Alaba, O.	PDF	N/A	Warming treatments shift the temporal dynamics of diversity and composition of bacteria in wild blueberry soils.
来自肠道细菌的D-乳酸通过驱动赖氨酸D-乳酸化来调节肝脏细胞的转录	Zang, Y.	PDF	N/A	D-lactate derived from intestinal bacteria drives lysine D-lactylation to modulate transcription in liver cells
聚合酶θ介导的末端连接的细胞周期调控是其对BLM-DNA2缺失敏感性的基础	McBrine, C. P.	PDF	N/A	Cell cycle regulation of polymerase theta mediated end-joining underlies its sensitivity to loss of BLM-DNA2
顺式调控元件之间的协同作用可以使凝聚蛋白对于远端增强子功能变得可有可无。	Hansen, K. L.	PDF	N/A	Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
秀丽隐杆线虫中Sjögrens综合征核抗原1的同源物对于维持中心粒的结构完整性和双极有丝分裂纺锤体的组装是必需的。	Pfister, J. A.	PDF	N/A	The C. elegans homolog of Sjögrens Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly
VAPA介导利什曼原虫亚马逊种与宿主巨噬细胞之间的脂质交换。	Gdovinova, I.	PDF	N/A	VAPA mediates lipid exchange between Leishmania amazonensis and host macrophages
EASI-ORC：一种用于酵母细胞器-RNA共定位测量中高效分析和分割smFISH图像的管道	Garin, S.	PDF	N/A	EASI-ORC: A Pipeline for the Efficient Analysis and Segmentation of smFISH Images for Organelle-RNA Colocalization Measurements in Yeast
解析单细胞中自主酶的变异性	Gnann, C.	PDF	N/A	Dissecting autonomous enzyme variability in single cells
一种体外有丝分裂后的鼠类作为肌肉损伤和修复的模型	Galluccio, A.	PDF	N/A	A post-mitotic in vitro murine as a model of muscle damage and repair
A-C连接子控制着中心粒的粘附和复制。	Bournonville, L.	PDF	N/A	The A-C Linker controls centriole cohesion and duplication
ATAD2通过HIRA/组蛋白H3.3依赖的机制驱动染色质动态变化。	Liakopoulou, A.	PDF	N/A	ATAD2 drives HIRA/histone H3.3-dependent chromatin dynamics
内皮细胞PROX1诱导中枢神经系统血脑屏障破坏	Gonzalez Hernandez, S.	PDF	N/A	ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM
斑马鱼的种质稳定性需要母源的Tdrd6a和Tdrd6c	Consorte, A.	PDF	N/A	Germplasm stability in zebrafish requires maternal Tdrd6a and Tdrd6c
分析受保护与未受保护潮池的生物多样性	Chen, V.	PDF	N/A	Analyzing Biodiversity in Protected vs. Unprotected Tide Pools
通过将基因表达建模为二元性状，量化系统发育上的转录组周转	Thompson, A.	PDF	N/A	Quantifying transcriptome turnover on phylogenies bymodeling gene expression as a binary trait
二倍体有性生殖种群中的固定概率	Shi, Z.	PDF	N/A	Fixation probability in a diploid sexually reproducing population
瑞典牛品种的人口历史：估计与模型检验	Adepoju, D.	PDF	N/A	Population history of Swedish cattle breeds: estimates and model checking
雌性生殖系特异性蛋白Sakura与Otu相互作用，对生殖干细胞的更新和分化以及卵子发生至关重要。	Azlan, A.	PDF	N/A	Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis
基于k-mer的小麦集合全基因组关联分析揭示了白粉病抗性的新来源和多样性	Jaegle, B.	PDF	N/A	k-mer-based GWAS in a wheat collection reveals novel and diverse sources of powdery mildew resistance
一种基于基因型的方法识别了犬类中的腭裂和其他表型的变异	Buckley, R. M.	PDF	N/A	A genotype-first approach identifies variants for orofacial clefts and other phenotypes in dogs
定量蛋白质组质谱法分析蛋白激酶以确定人类激酶组的动态异质性	East, M. P.	PDF	N/A	Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome
尼帕病毒复制的结构基础	Sala, F. A.	PDF	N/A	Structural basis of Nipah virus replication
重复基因组区域中的长片段缺失签名记录了体细胞进化，并能够敏感地检测微卫星不稳定性。	Guo, Q.	PDF	N/A	Long deletion signatures in repetitive genomic regions track somatic evolution and enable sensitive detection of microsatellite instability
整合生物信息学与人工智能方法以识别影响蛋白质稳定性和功能的破坏性STAT1变异体	Kamal, E.	PDF	N/A	Integrating Bioinformatics and Artificial Intelligence Methods to identify disruptive STAT1 variants impacting Protein Stability and Function
基于深度学习的主要组织相容性复合体中的基序发现：入门指南	Alvarez, B.	PDF	N/A	Deep Learning-Based Motif Discovery in MajorHistocompatibility Complex: A Primer
一个基于浏览器的平台，用于在HPC环境中存储、可视化和分析大规模的3D图像。	Walker, L. A.	PDF	N/A	A browser-based platform for storage, visualization, and analysis of large-scale 3D images in HPC environments
基于优化后的蓝图进行ATP酶的从头设计，该蓝图适用于容纳P-loop基序	Kosugi, T.	PDF	N/A	De novo design of ATPase based on the blueprint optimized for harboring the P-loop motif
超越平面：鱼群在三维空间中采用梯形编队	Ko, H.	PDF	N/A	Beyond planar: fish schools adopt ladder formations in 3D
结构集合的弹性分析揭示了AAA+马达中手对手传递的能量基础	Mello, V. H.	PDF	N/A	Elastic analysis of structural ensemble reveals the energetic basis of hand-over-hand in a AAA+ motor
生物膜流丝的应力硬化行为	Savorana, G.	PDF	N/A	Stress-hardening behaviour of biofilm streamers
计算分析Nitazene衍生物在μ-阿片受体上的结合姿态	Clayton, J.	PDF	N/A	Computational Analysis of the Binding Poses of Nitazene Derivatives at the mu-Opioid Receptor
力学约束组织三维组织并协调肌肉分化	Nagle, I.	PDF	N/A	Mechanical constraints organize 3D tissues and orchestrate muscle differentiation
APC协调GSK3对SETD8的磷酸化，以抑制结直肠癌	Cramer, Z.	PDF	N/A	APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer
时间多模态单细胞分析揭示了CAR-T细胞与胶质母细胞瘤的动态相互作用及对抗原阴性肿瘤细胞的靶向作用	Zhang, D. Y.	PDF	N/A	Temporal multi-modal single-cell analyses reveal dynamic interactions of CAR-T cells with glioblastoma and targeting of antigen-negative neoplastic cells
STAT1与YAP1之间的正反馈环路刺激脂质生物合成，加速突变型KRAS结直肠癌细胞的生长，并促进化疗耐药性。	Wang, S.	PDF	N/A	A feedforward loop between STAT1 and YAP1 stimulates lipid biosynthesis, accelerates tumor growth, and promotes chemotherapy resistance in mutant KRAS colorectal cancer.
一种新的空间多组学方法，通过单个组织切片深入表征人类癌症组织	Adimi, Y.	PDF	N/A	A new spatial multi-omics approach to deeply characterize human cancer tissue using a single tissue section
降雨对田间条件下空气中小麦锈菌孢子昼夜周期性的破坏作用	Suffert, F.	PDF	N/A	Disruptive effect of rainfalls on the diurnal periodicity of airborne wheat rust spore under field conditions
系统遗传学解析阿尔茨海默病大脑基因表达网络	Zhao, P.	PDF	N/A	Systems genetic dissection of Alzheimer's disease brain gene expression networks
基于深度学习的图像分类揭示了病毒感染期间细胞死亡命运的异质性执行	Centofanti, E.	PDF	N/A	Deep learning-based image classification reveals heterogeneous execution of cell death fates during viral infection
建模上皮-间质转化（EMT）的动力学揭示了与泛癌中间状态和可塑性相关的基因	McDermott, M.	PDF	N/A	Modeling the dynamics of EMT reveals genes associated with pan-cancer intermediate states and plasticity
发现具有切换无限GPFA的时序组合神经流形	Yu, C.	PDF	N/A	Discovering Temporally Compositional Neural Manifolds with Switching Infinite GPFA
Shank3B-/-小鼠中前额叶皮层（mPFC）PV中间神经元早期产后功能障碍	Peixoto, R. T.	PDF	N/A	Early Postnatal Dysfunction of mPFC PV Interneurons in Shank3B-/- Mice
神经甾体敏感的δ-GABAA受体对成年小鼠味觉岛叶皮层甜味偏好的调节作用	Yevoo, P. E.	PDF	N/A	Modulation of sweet preference by neurosteroid-sensitive, δ-GABAA receptors in adult mouse gustatory insular cortex
JN.1加强疫苗对SARS-CoV-2变异株KP.3.1.1和XEC的中和作用影响	Arora, P.	PDF	N/A	Impact of JN.1 booster vaccination on neutralisation of SARS-CoV-2 variants KP.3.1.1 and XEC
CMTM4是一种粘附调节因子，调控海胆胚胎中骨骼模式形成和初级间充质细胞迁移。	Descoteaux, A. E.	PDF	N/A	CMTM4 is an adhesion modulator that regulates skeletal patterning and primary mesenchyme cell migration in sea urchin embryos
土壤pH值影响感染个体宿主的噬菌体群落的组成	Lee, S.	PDF	N/A	Soil pH influences the composition of bacteriophage communities infecting individual hosts
一个统一的理论框架，用于解释不同尺度下围栏实验结果的矛盾，以评估蜱传疾病的风险	Freedman, A. S.	PDF	N/A	A unifying theoretical framework for tick-borne disease risk to explain conflicting results of exclosure experiments across scales
在感染野生禾本科植物的真菌物种中，种间杂交作为附加染色体起源的途径	Fagundes, W. C.	PDF	N/A	Interspecies hybridization as a route of accessory chromosome origin in fungal species infecting wild grasses
规模化衰老：来自狗衰老项目的年轻犬只和大型犬种显示出加速的表观遗传衰老。	McCoy, B. M.	PDF	N/A	Aging at scale: Younger dogs and larger breeds from the Dog Aging Project show accelerated epigenetic aging.
通过计算机分析和体外功效研究探索锦葵色素和芍药花色素作为潜在抗利什曼原虫药物的潜力	Goyzueta-Mamani, L. D.	PDF	N/A	Exploring the Potential of Malvidin and Echiodinin as Probable Antileishmanial Agents Through In Silico Analysis And In Vitro Efficacy
通过对比对抗开放集域适应实现单细胞数据整合与细胞类型注释	Aminzadeh, F.	PDF	N/A	Single-Cell Data Integration and Cell Type Annotation through Contrastive Adversarial Open-set Domain Adaptation
辉瑞-生物技术与莫德纳新冠疫苗中脂质纳米颗粒的比较分析：来自分子动力学模拟的洞察	Biswal, M. R.	PDF	N/A	Comparative Analysis of Lipid Nanoparticles in Pfizer-BioNTech and Moderna COVID-19 Vaccines: Insights from Molecular Dynamics Simulations
在限制压力下三维菌落中应激响应细菌的生长	Rahbar, S.	PDF	N/A	Growth of Stress-Responsive Bacteria in 3D Colonies under Confining Pressure
SATB2和circ3915 RNA的染色质失调驱动了类似KRAS的致癌转化	Eleazer, R.	PDF	N/A	SATB2 and circ3915 RNA chromatin dysregulation drive KRAS-like oncogenic transformation
来自白垩纪缅甸琥珀的一个显著的缨翅目家族，Miralidae stat. nov.（= Dinglidae syn. nov.；半翅目：胸喙亚目）	Ivanov, G.	PDF	N/A	A remarkable psyllomorph family from Cretaceous Burmese amber, Miralidae stat. nov. (= Dinglidae syn. nov.; Hemiptera: Sternorrhyncha)
扰动诱发皮层活动的重测信度反映了反应性平衡控制中稳定的个体差异	Mirdamadi, J. L.	PDF	N/A	Test-retest reliability of perturbation-evoked cortical activity reflects stable individual differences in reactive balance control
SPLASH-structure：一种从原始测序数据中识别RNA二级结构的统计方法，无需进行多序列比对	Wang, J. F.	PDF	N/A	SPLASH-structure: a statistical approach to identify RNA secondary structures from raw sequencing data, bypassing multiple sequence alignment
Latexin通过促进平滑肌细胞增殖和巨噬细胞迁移来促进新生内膜的形成。	Kazama, K.	PDF	N/A	Latexin facilitates neointimal formation via promoting smooth muscle cell proliferation and macrophage migration
# BioRxiv 2024-10-03 Papers

标题	作者	PDF链接	代码仓库	Title
肿瘤细胞-脂肪细胞间隙连接激活脂肪分解，并促进乳腺癌的发生	Williams, J.	PDF	N/A	Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
气味通过果蝇的味觉受体神经元驱动进食。	Wei, H.-p.	PDF	N/A	Odors drive feeding through gustatory receptor neurons in Drosophila
超声波抑制SARS-CoV-2体外感染性	Veras, F. P.	PDF	N/A	Ultrasound inhibits SARS-CoV-2 infectivity in vitro
人类自噬起始ULK1C:PI3KC3-C1超复合物的结构与激活	Chen, M.	PDF	N/A	Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
TIM-4 识别表达 RORγT 驱动的促炎细胞因子模块的效应 B 细胞，促进免疫应答	Ding, Q.	PDF	N/A	TIM-4 Identifies Effector B cells Expressing a RORγT-driven Proinflammatory Cytokine Module That Promotes Immune responsiveness
打开物种箱：简约的微观物种形成模型对宏观进化的启示	Couvert, E.	PDF	N/A	Opening the species box: What parsimonious microscopic models of speciation have to say about macroevolution
可解释的多尺度结构保留单细胞RNA测序数据嵌入模型	Novak, D.	PDF	N/A	Interpretable models for scRNA-seq data embedding with multi-scale structure preservation
通过体内注射和电穿孔裸露mRNA恢复患有少弱畸精子症小鼠的精子生育力	Vilpreux, C.	PDF	N/A	Sperm fertility restoration in mice suffering from oligo-astheno-teratozoospermia by in vivo injection and electroporation of naked mRNA
共享的句法和形态结构神经计算：来自汉语普通话的证据	Yu, X.	PDF	N/A	Shared neural computations for syntactic and morphological structures: evidence from Mandarin Chinese
HairSplitter：从长且有噪声的读取中进行单体型组装	Faure, R.	PDF	N/A	HairSplitter: haplotype assembly from long, noisy reads
从BioModels中筛选模型：开发创建OMEX文件的工作流程	Xu, J.	PDF	N/A	Curating models from BioModels: Developing a workflow for creating OMEX files
内侧前额叶皮层的特定层次输入与应激易感性相关	Solakoglu, S. T.	PDF	N/A	Layer-specific input to medial prefrontal cortex is linked to stress susceptibility
纹状体脑片中持续活动模式对多巴胺释放的调控	Boumhaouad, S.	PDF	N/A	Regulation of dopamine release by tonic activity patterns in the striatal brain slice
整合跨振荡功率频段的数据可预测癫痫病灶区：频率范围探索癫痫病灶区（FREEZ）识别算法	O'Leary, S.	PDF	N/A	Integrating Data Across Oscillatory Power Bands Predicts the Epileptogenic Zone: the Frequency Range Explorer Epileptogenic Zone (FREEZ) Identification Algorithm
佐剂递送方法及纳米颗粒电荷对肽酰胺微泡疫苗生物活性的影响	Zhang, R.	PDF	N/A	Adjuvant Delivery Method and Nanoparticle Charge Influence Peptide Amphiphile Micelle Vaccine Bioactivity
两栖动物基因组学联盟：推动两栖动物研究与保护的基因组学和遗传资源发展	Kosch, T. A.	PDF	N/A	The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation
高度相似的氯代烷烃还原脱卤酶的动力学对比	Picott, K.	PDF	N/A	Contrasting kinetics of highly similar chloroalkane reductive dehalogenases
行走于蜿蜒小径时的侧向不稳定性概率	Render, A. C.	PDF	N/A	Probability of Lateral Instability While Walking on Winding Paths
流感病毒感染经历会改变肺部结构细胞的动态，从而在病毒再次攻击后迅速获得免疫保护。	Worrell, J. C.	PDF	N/A	Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
小说口头指令招募了时间变量信息维度抽象神经模式	Pena, P.	PDF	N/A	Novel verbal instructions recruit abstract neural patterns of time-variable information dimensionality
评估AEV01在胶质瘤和肝细胞癌中的抗肿瘤疗效及安全性：体外和体内研究方法。	Biswas, I.	PDF	N/A	Evaluating the Anti-tumor efficacy and safety of AEV01 in Glioma and Hepatocellular Carcinoma: An In Vitro and In Vivo approach.
皮质醇动态变化及斑马鱼幼体暴露于重复应激下的糖皮质激素受体依赖性反馈调节	Castillo-Ramirez, L. A.	PDF	N/A	Cortisol dynamics and GR-dependent feedback regulation in zebrafish larvae exposed to repeated stress
气候变化、农药和药物对孔雀鱼（Nothobranchius furzeri）生命史和行为综合影响的研究	Kim, D.	PDF	N/A	The combined impact of climate change, pesticides and pharmaceuticals on life history and behaviour in killifish (Nothobranchius furzeri)
多巴胺与时间折扣：重新审视药理学与个体差异	Smith, E.	PDF	N/A	Dopamine and temporal discounting: revisiting pharmacology and individual differences
大小-重量错觉及其超越：一种感知重量的新模型	Pisu, V.	PDF	N/A	The size-weight illusion and beyond: a new model of perceived weight
一种新的Betaflexivirus属病毒在Ferraria crispa植物中被发现	Dekker, R. J.	PDF	N/A	A new Betaflexivirus species in Ferraria crispa plants
在Lachenalia植物中发现的新型Phenuivirus物种揭示了5'和3' RNA序列基序之间可能的协同进化	Dekker, R. J.	PDF	N/A	Discovery of a new Phenuivirus species in Lachenalia plants reveals possible co-evolution between 5' and 3' RNA sequence motifs
结构蛋白质组学揭示了孕酮受体的顺序启动机制	Mann, M. D.	PDF	N/A	Structural proteomics defines a sequential priming mechanism for the progesterone receptor
人类视觉皮层在准备期间的双格式注意模板	Chen, Y.	PDF	N/A	Dual-format attentional template during preparation in human visual cortex
缺失但未受糖皮质激素调节的促肾上腺皮质激素释放激素（Crh）调控小鼠的焦虑样行为	Friedman, H. R.	PDF	N/A	Absent, but not glucocorticoid-modulated, corticotropin-releasing hormone (Crh) regulates anxiety-like behaviors in mice
Lumen电荷调控β-桶状纳米孔中的忆阻离子传输	Mayer, S. F.	PDF	N/A	Lumen charge governs memristive ion transport in β-barrel nanopores
调节秀丽隐杆线虫进入持久幼虫状态决策的神经元活动	Prakash, S. J.	PDF	N/A	Neuronal activity regulating the dauer entry decision in Caenorhabditis elegans
RAPDOR：利用Jensen-Shannon距离进行复杂蛋白质组学数据集的计算分析	Hemm, L.	PDF	N/A	RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets
经验塑造了嗅觉表征沿着皮层-海马路径的转变	Schiltz, E.	PDF	N/A	Experience shapes the transformation of olfactory representations along the cortico-hippocampal pathway
RNA结合蛋白Musashi1与病毒基因组RNA相互作用，并通过抑制翻译来限制SARS-CoV-2感染。	Ganguli, S.	PDF	N/A	RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation
阿塔卡马沙漠的土壤生物多样性在不同多样性水平上呈现出明显的模式。	Villegas, L.	PDF	N/A	Soil biodiversity in the Atacama Desert shows distinct patterns at different diversity levels
ClassiCOL：通过胶原蛋白肽模糊性进行古代物种分类的LC-MS/MS分析	Engels, I.	PDF	N/A	ClassiCOL: LC-MS/MS analysis for ancient species Classification via Collagen peptide ambiguation
从太平洋牡蛎中分离得到的Gallaecimonas pentaromativorans菌株10A的基因组显示了其降解碳氢化合物和CRISPR-Cas防御的潜力。	Gouin, Y.	PDF	N/A	The genome of Gallaecimonas pentaromativorans strain 10A, isolated from a Pacific oyster, reveals the potential for hydrocarbon degradation and CRISPR-Cas defense
基于转录组的全基因组长非编码RNA（lncRNA）在冈比亚按蚊中的鉴定	Xu, J.	PDF	N/A	Transcriptome-based identification of long noncoding RNAs (lncRNAs) across the genome of Anopheles gambiae
开发并验证一种计算工具，用于预测高级别浆液性卵巢癌患者细胞的治疗结果	Cortesi, M.	PDF	N/A	Development and validation of a computational tool to predict treatment outcomes in cells from High-Grade Serous Ovarian Cancer patients
利用全基因组代谢网络分析神经发育，研究自闭症谱系障碍中的细胞代谢功能障碍	Pourmajidian, M.	PDF	N/A	Investigation of cell metabolism dysfunction in autism spectrum disorders using genome-scale metabolic network analysis of neuronal development
期望引发音乐引发的寒颤	de Fleurian, R.	PDF	N/A	Expectation elicits music-evoked chills
亲社会奖励与言语接收阈值相关，而年龄与噪声中言语感知的主观评分相关。	Oakeson, R. J.	PDF	N/A	Prosocial reward relates to speech reception thresholds and age relates to subjective ratings of speech perception in noise
常染色体显性额颞叶痴呆临床表现中的性别差异	Memel, M.	PDF	N/A	Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia
雷帕霉素免疫调节利用时间依赖性的淋巴结结构改变、白细胞迁移和肠道微生物群的变化	Wu, L.	PDF	N/A	Rapamycin Immunomodulation Utilizes Time-Dependent Alterations of Lymph Node Architecture, Leukocyte Trafficking, and Gut Microbiome
在产前暴露于较高水平母体炎症的中年/老年成人中，海马神经突密度降低	Mohyee, R. A.	PDF	N/A	Decreased hippocampal neurite density in middle-aged/aging adults following prenatal exposure to higher levels of maternal inflammation
全球木本植物群落的代谢生长机制与理论生长潜力	Shu, S.	PDF	N/A	Metabolic growth mechanisms and theoretical growth potential of global woody plant communities
水生食物对小岛屿发展中国家人类营养摄入和充足性的贡献	Zamborain-Mason, J.	PDF	N/A	The contribution of aquatic foods to human nutrient intake and adequacy in a Small Island Developing State
BCL-xL复合物尾部锚定对BH3-in-沟槽相互作用的全局调节限制了BH3模拟拮抗作用。	Maillet, L.	PDF	N/A	Allosteric regulation of BH3-in-groove interactions by tail anchors of BCL-xL complexes limits BH3 mimetic antagonism.
细胞内核周β-肾上腺素受体在定义信号分隔和病理心脏重塑中的独特作用	Turcotte, M. G.	PDF	N/A	The Unique Role of Intracellular Perinuclear β-Adrenergic Receptors in defining Signaling Compartmentation and Pathological Cardiac Remodeling
部分共享的多模态嵌入学习细胞状态的整体表示	Zhang, X.	PDF	N/A	Partially Shared Multi-Modal Embedding Learns Holistic Representation of Cell State
使用新型荧光HPLC法量化小GTP酶的激活状态	Araki, M.	PDF	N/A	Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay
GLA-3介导秀丽隐杆线虫生殖细胞中的应激反应：Tristetraprolin（TTP）家族的关键作用	Salinas, L. S.	PDF	N/A	GLA-3 Mediates Stress Response in Caenorhabditis elegans Germ Cells: A key role of the Tristetraprolin (TTP) Family
一种可诱导且可逆的系统，用于调控秀丽隐杆线虫中不饱和脂肪酸的生物合成	Battista, B.	PDF	N/A	An inducible and reversible system to regulate unsaturated fatty acid biosynthesis in C. elegans
胶质母细胞瘤的侵袭依赖于肌动蛋白-肌球蛋白的收缩性和金属蛋白酶的活性。	Sumajit, H.	PDF	N/A	Glioblastoma invasion relies on actomyosin contractility and metalloproteinase activity
基于Hsp90-Tau相互作用的合成伴侣蛋白抑制病理性Tau聚集并恢复生理性Tau-微管相互作用	Di Lorenzo, D.	PDF	N/A	Synthetic chaperone based on Hsp90-Tau interaction inhibits pathological Tau aggregation and rescues physiological Tau-Microtubule interaction
PHD3-FOXO3轴调节小胶质细胞中的I型干扰素反应，加剧阿尔茨海默病进展	Sanchez-Garcia, M. A.	PDF	N/A	The PHD3-FOXO3 axis modulates the interferon type I response in microglia aggravating Alzheimer's disease progression
雌性小鼠犁鼻器中雄性特征的表达及其在动情周期中的稳定性	Ben-Shaul, Y.	PDF	N/A	Representation of male features in the female mouse Accessory Olfactory Bulb, and their stability during the estrus cycle
检测身体对组织过度生长的生殖激素制动器：micrin/SgII-70	Hart, J. E.	PDF	N/A	Detecting the bodys reproductive hormonal brake against tissue overgrowth: micrin/SgII-70
高血压Bph/2小鼠与正常血压Bpn/3小鼠之间淋巴细胞亚群的差异组成及激活状态	Dattmore, D. A.	PDF	N/A	Differential composition of lymphocyte subpopulations and activation between the hypertensive Bph/2 and normotensive Bpn/3 mouse strains
荷斯坦奶牛生乳中细菌群落的组成与肺炎克雷伯菌临床乳腺炎感染的发生相关	O'Brien, B.	PDF	N/A	The Composition of the Bacterial Community in Raw Milk from Holstein Dairy Cattle Correlated with the Occurrence of Klebsiella pneumoniae Clinical Mastitis Infections
环境基质和水分是决定在简化土壤模拟环境中表达的微生物表型的关键因素。	Rodriguez-Ramos, J. A.	PDF	N/A	Environmental matrix and moisture are key determinants of microbial phenotypes expressed in a reduced complexity soil-analog
一项针对三个国家的肠道微生物组分析显示，与饮食相关的分类群关联因地理位置和菌株而异。	Khatib, L.	PDF	N/A	A three-country analysis of the gut microbiome indicates taxon associations with diet vary by location and strain
Sciphy：一种使用顺序遗传谱系追踪数据的贝叶斯系统发育框架。	Seidel, S.	PDF	N/A	Sciphy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data.
鸟类捕食评估的准确性：相机陷阱测试橡皮泥毛虫作为猎物模型的有效性	SCHILLE, L.	PDF	N/A	Accuracy in bird predation assessment: Camera traps testing the efficacy of plasticine caterpillars as prey models
重建MAPK信号网络的深层系统发育：通过多层次协同进化扩展实现功能特化	Huang, E.	PDF	N/A	Reconstructing the deep phylogeny of the MAPK signaling network: functional specialization via multi-tier coevolutionary expansion
念珠菌基因组数据库：注释与可视化更新	Lew-Smith, J.	PDF	N/A	The Candida Genome Database: Annotation and Visualization Updates
人工照明影响捕食性臭虫Orius insidiosus（Say）对西方花蓟马Frankliniella occidentalis（Pergande）的捕食效果	Canovas, M. L.	PDF	N/A	Artificial lighting affects the predation performance of the predatory bug Orius insidiosus (Say) against the Western flower thrips Frankliniella occidentalis (Pergande)
一项简单的措施能减少小鼠的食量并降低肥胖率	Barrett, M. R.	PDF	N/A	A simple action reduces food intake and obesity in mice
使用HarmoDecon缓解空间分辨转录组学中细胞类型反卷积的多尺度偏差	Wang, Z.	PDF	N/A	Mitigation of multi-scale biases in cell-type deconvolution for spatially resolved transcriptomics using HarmoDecon
ProteusAI：一个开源且用户友好的平台，用于机器学习引导的蛋白质设计和工程	Funk, J.	PDF	N/A	ProteusAI: An Open-Source and User-Friendly Platform for Machine Learning-Guided Protein Design and Engineering
规范游戏：重新思考精准肿瘤学中药物反应预测的评估	Codice, F.	PDF	N/A	The Specification Game: Rethinking the Evaluation of DrugResponse Prediction for Precision Oncology
scChat：基于大型语言模型的单细胞RNA测序分析上下文助手	Lu, Y.-C.	PDF	N/A	scChat: A Large Language Model-Powered Co-Pilot for Contextualized Single-Cell RNA Sequencing Analysis
比较分析Endoxifen、他莫昔芬和氟维司群：一种生物信息学方法揭示乳腺癌的作用机制	Remmel, H. L.	PDF	N/A	Comparative analysis of Endoxifen, Tamoxifen and Fulvestrant: A Bioinformatics Approach to Uncover Mechanisms of Action in Breast Cancer
使用5-氨基乙酰丙酸诱导的光敏化光动力疗法在获得性药物抗性的胰腺癌细胞中的疗效得到增强	Liu, Y.	PDF	N/A	Efficacy of photodynamic therapy using 5-aminolevulinic acid-induced photosensitization is enhanced in pancreatic cancer cells with acquired drug resistance
调节性T细胞通过淋巴毒素信号与肿瘤和内皮细胞进行交流。	Piao, W.	PDF	N/A	Regulatory T cells crosstalk with tumor and endothelium through lymphotoxin signaling
Erbin通过与NHERF1和Ezrin相互作用，在HER2阳性乳腺癌中稳定膜ErbB2信号复合物。	JEONG, J.	PDF	N/A	Erbin interacts with NHERF1 and Ezrin to stabilize a membrane ErbB2 signaling complex in HER2-positive breast cancer
在心脏和肌肉中实现强效且持久的基因调控，使用化学定义的siRNAs	Fakih, H. H.	PDF	N/A	Potent and durable gene modulation in heart and muscle with chemically defined siRNAs
与槐叶苹共培养的水稻植株改变了根系结构和发育阶段的时机	Cannavo', S.	PDF	N/A	Co-cultivating rice plants with Azolla filiculoides modifies root architecture and timing of developmental stages
与满江红共培养对整株水稻代谢组的影响超出了传统无机氮肥的作用	Consorti, E.	PDF	N/A	Co-cultivation with Azolla affects the metabolome of whole rice plant beyond canonical inorganic nitrogen fertilization
细胞可塑性多步骤完成过程模型	Chen, C. M.	PDF	N/A	A multi-step completion process model of cell plasticity
揭示赤拟谷盗（Tribolium castaneum，Herbst, 1797）在小麦粉中的化学与行为生态学：面粉代谢成分的改变及化学信号在调节甲虫行为和调控种群增长中的作用。	Das, S.	PDF	N/A	Unveiling the chemical and behavioural ecology of Tribolium castaneum (Herbst, 1797) in wheat flour: Alterations in flour metabolic content and the role of chemical cues in modulating beetles' behaviour and regulating population growth.
从斑马鱼中获得的稳定初级脑细胞培养物显示，scn1lab突变体中的非神经元细胞出现过度增殖。	Odierna, L.	PDF	N/A	Stable primary brain cell cultures from zebrafish reveal hyperproliferation of non-neuronal cells from scn1lab mutants
细菌补充剂通过肠-脑轴减轻盆腔放疗引起的大脑代谢紊乱：一项多组学研究	Venkidesh, B. S.	PDF	N/A	Bacterial Supplements Attenuate Pelvic Irradiation-Induced Brain Metabolic Disruptions via the Gut-Brain Axis: A Multi-Omics Investigation
功能失调的LHX6苍白球-丘脑底核投射在小鼠Leigh综合征模型中介导癫痫发作	Sanchez-Benito, L.	PDF	N/A	Dysfunctional LHX6 pallido-subthalamic projections mediate epileptic events in a mouse model of Leigh Syndrome
设计实验方案以在受控实验室环境中引发警觉性变化	Zahran, S.	PDF	N/A	Designing Experimental Protocols to Elicit Vigilance Variations in Controlled Laboratory Settings
在PrP.TDP43-315 ALS模型中，采用组合方法治疗ALS；并发症与困境	Fromholt, S.	PDF	N/A	A combinatorial approach to ALS therapies in the PrP.TDP43-315 model of ALS; complications and tribulations
过滤点过程能够有效捕捉神经电生理记录中的节奏性和宽带功率谱结构	Bloniasz, P. F.	PDF	N/A	Filtered Point Processes Tractably Capture Rhythmic And Broadband Power Spectral Structure in Neural Electrophysiological Recordings
脑干神经元协调膀胱和尿道括约肌以进行排尿	Li, X.	PDF	N/A	Brainstem neurons coordinate the bladder and urethra sphincter for urination
病原体在微生物毒力和宿主抵抗力变化中的致病性	Gupta, A.	PDF	N/A	Pathogenicity across variation in microbial virulence and host resistance
表达嵌合细胞因子受体的巨噬细胞在IL-10或TGFβ刺激下表现出炎症表型并具有抗肿瘤活性。	Traxel, S.	PDF	N/A	Macrophages expressing chimeric cytokine receptors have an inflammatory phenotype and anti-tumoral activity upon IL-10 or TGFβ stimulation
通过多种丁酰胆碱酯酶激活Vγ9Vδ2 TCR的冷冻电镜结构洞察	Zhang, M.	PDF	N/A	Cryo-EM structural insights into Vγ9Vδ2 TCR activation via multiple butyrophilins
TYK2抑制增强了Treg的分化和功能，同时防止了Th1和Th17的分化。	Tuomela, K.	PDF	N/A	TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differnetiation
第四代PDCD1驱动IL-10的CAR Tregs具有增强的抑制功能	Boardman, D. A.	PDF	N/A	Fourth generation CAR Tregs with PDCD1-driven IL-10 have enhanced suppressive function
发育中的人类肺部空间解析蓝图揭示了一种由WNT驱动微环境调控的基底细胞群体	Hsu, P. P.	PDF	N/A	A spatially-resolved blueprint of the developing human lung reveals a basal cell population regulated by a WNT-driven niche
在扁形动物的外上皮中，损伤诱导的转录对于组织再生至关重要。	Barai, P.	PDF	N/A	Injury-induced transcription in the planarian outer epithelium is critical for tissue regeneration
实验室进化的高温适应性大肠杆菌菌株的基因组分析	McGuire, B. E.	PDF	N/A	Genomic analysis of laboratory-evolved, heat-adapted Escherichia coli strains
mRNA表达受非核仁RNA聚合酶I的共同调控。	Carter, L. M.	PDF	N/A	mRNA expression is co-regulated by non-nucleolar RNA polymerase I
通过scDEEP-mC实现的高覆盖度、等位基因解析的单细胞DNA甲基化分析揭示了细胞谱系、X染色体失活状态及复制动力学	Spix, N. J.	PDF	N/A	High-coverage allele-resolved single-cell DNA methylation profiling by scDEEP-mC reveals cell lineage, X-inactivation state, and replication dynamics
一种新型行为装置，用于在大鼠中进行自发探索和操作性条件下的社会信息空间条件化	Wise, T. B.	PDF	N/A	A novel behavioral apparatus for spontaneous exploration and operant conditioning of social information under spatial conditions in rats
利用人工智能衍生平台确定针对主动脉瓣肌成纤维细胞激活的药物组合中的性别差异	Vogt, B. J.	PDF	N/A	Determining sex differences in drug combinations targeting aortic valve myofibroblast activation using an artificial intelligence derived platform
一种低成本、开源的3D打印机，适用于多材料和高通量直接墨水书写软性和活体材料的打印。	Weiss, J. D.	PDF	N/A	A low-cost, open-source 3D printer for multimaterial and high-throughput direct ink writing of soft and living materials
数字光处理3D打印技术实现了高效的人工心脏组织制造，用于疾病模型构建	Dhand, A. P.	PDF	N/A	Digital Light Processing 3D Printing enables High Throughput Fabrication of Human Engineered Heart Tissues for Disease Modeling
工程化全肺用于组织生物学研究	Greaney, A. M.	PDF	N/A	Engineered Whole Lungs for Tissue Biology
纳米级可生物降解打印技术用于设计调节疫苗递送动力学	Peeler, D. J.	PDF	N/A	Nanoscale biodegradable printing for designed tuneability of vaccine delivery kinetics
针对蛋白酶降解的疫苗（PROTAVs）用于强效肿瘤联合免疫疗法	Wang, Q.	PDF	N/A	Proteolysis-targeting vaccines (PROTAVs) for robust tumor combination immunotherapy
BioLLMNet：通过专用跨LLM转换网络增强RNA相互作用预测	Tahmid, M. T.	PDF	N/A	BioLLMNet: Enhancing RNA-Interaction Prediction with a Specialized Cross-LLM Transformation Network
PertEval-scFM：基准测试单细胞基础模型用于扰动效应预测	Wenteler, A.	PDF	N/A	PertEval-scFM: Benchmarking Single-Cell Foundation Models for Perturbation Effect Prediction
scMODAL：一种通用的深度学习框架，用于具有特征链接的综合单细胞多组学数据对齐	Wang, G.	PDF	N/A	scMODAL: A general deep learning framework for comprehensive single-cell multi-omics data alignment with feature links
临床和分子变异特性对变异效应预测工具的校准和性能的影响	Isakov, O.	PDF	N/A	The Impact of Clinical and Molecular Variant Properties on Calibration and Performance of Variant Effect Prediction Tools
心室心律失常综合征相关KCNJ2突变的原子级研究	Munawar, S.	PDF	N/A	Atomic-Level Investigation of KCNJ2 Mutations Associated with Ventricular Arrhythmic Syndrome Phenotypes
表型可塑性可以是对波动环境的一种进化反应。	Garcia-Galindo, P.	PDF	N/A	Phenotypic plasticity can be an evolutionary response to fluctuating environments
CYP3A5抑制导致G1/S阻滞，并与CDK4/6抑制剂协同抑制前列腺癌细胞生长：减少健康差异的意义	Sharma, J.	PDF	N/A	CYP3A5 inhibition causes G1/S blockade and synergizes with CDK4/6 inhibitor to suppress prostate cancer cell growth: Implications in reducing health disparity
靶向FEN1以提高PARP抑制剂在三阴性乳腺癌中的疗效	Frederick, M. I.	PDF	N/A	Targeting FEN1 to enhance efficacy of PARP inhibition in triple-negative breast cancer
线粒体活性氧在肥厚型心肌病中引起心律失常	Kohlhaas, M.	PDF	N/A	Mitochondrial reactive oxygen species cause arrhythmias in hypertrophic cardiomyopathy
茄科中一个生物合成基因簇的亚功能化和表观遗传调控	Priego-Cubero, S.	PDF	N/A	Sub-functionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae
脯氨酸-2'-脱氧麦根酸（PDMA）通过缓解石灰性碱性条件下大豆的缺铁症状，提高了种子质量和产量。	Kaya, Z.	PDF	N/A	Proline-2'-deoxymugineic acid (PDMA) increases seed quality and yield by alleviating iron deficiency symptoms in soybean under calcareous-alkaline conditions
异源性烟碱乙酰胆碱受体通过在运动和感觉整合位点传递GABA能信号来促进睡眠。	Yumita, T.	PDF	N/A	A heteromeric nicotinic acetylcholine receptor promotes sleep by relaying GABAergic signals within a locus of motor and sensory integration
通过抑制Notch信号通路实现感觉毛细胞的再生与前庭功能的恢复	Lahlou, H.	PDF	N/A	Regeneration of Sensory Hair Cells and Restoration of Vestibular Function by Notch Inhibition
边缘光谱估计	Patel, S.	PDF	N/A	Spectral estimation at the edge
性别在神经元对缺氧压力的反应中是否起作用？	Voogd, E. J. H. F.	PDF	N/A	Does sex matter in neurons response to hypoxic stress?
生理和损伤诱导的微胶质细胞动态变化贯穿整个生命周期	Tieu, T.	PDF	N/A	Physiological and injury-induced microglial dynamics across the lifespan
婴儿开放大脑：一个婴儿脑部分割的开源仓库	Feczko, E. J.	PDF	N/A	Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations
下午至傍晚的明亮光线暴露会减少青少年晚些时候的褪黑素分泌。	Lazar, R.	PDF	N/A	Afternoon to early evening bright light exposure reduces later melatonin production in adolescents
短期热量限制或白藜芦醇补充剂改变了雄性和雌性大鼠的大规模脑网络连接	van Rooij, J. R. A.	PDF	N/A	Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats
使用雾化模式识别受体激动剂的免疫疗法可恢复严重免疫麻痹，并改善流感相关性肺曲霉病小鼠的预后。	Garcia, J. P.	PDF	N/A	Immunotherapy with nebulized pattern recognition receptor agonists restores severe immune paralysis and improves outcomes in mice with influenza-associated pulmonary aspergillosis
心肌炎和中性粒细胞介导的血管渗漏，而非细胞因子风暴，与致命的小鼠钩端螺旋体病相关。	Papadopoulos, S.	PDF	N/A	Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis
果蝇腹部组织大小变化时的生长补偿	Ferreira, A.	PDF	N/A	Growth compensation upon changes in tissue size in the Drosophila abdomen
组织特异性转录组学揭示了专家幼鱼下颌差异背后的新颅面基因	Palominos, M. F.	PDF	N/A	Tissue-specific transcriptomics uncovers novel craniofacial genes underlying jaw divergence in specialist pupfishes
红砂岩表面微生物群落：尽管在分散限制和异质选择下分类学上存在差异，但功能趋同	Wang, B.	PDF	N/A	Red sandstone surface microbiota: functional convergence despite taxonomic divergence under dispersal limitation and hetero selection
热带北太平洋四种新型绿藻病毒的基因组多样性和全球分布	Bedi de Silva, A.	PDF	N/A	Genomic diversity and global distribution of four new prasinoviruses from the tropical North Pacific
硬蜱幼虫更喜欢含有伯氏疏螺旋体感染且皮质类固醇浓度较低的血液。	Vanroy, T.	PDF	N/A	Ixodes ricinus nymphs prefer blood with Borrelia infection and low corticosteroid concentration
放射虫的多样性与演化：超越海洋之星	Mendez Sandin, M.	PDF	N/A	Diversity and evolution of Radiolaria: Beyond the stars of the ocean
蛋白质-蛋白质相互作用塑造了遗传变异对蛋白质表达和复杂性状的反式调控影响	Li, J.	PDF	N/A	Protein-protein interactions shape trans-regulatory impact of genetic variation on protein expression and complex traits
一个关于秀丽隐杆线虫RNAi遗传的遗传框架	Ketting, R. F.	PDF	N/A	A genetic framework for RNAi inheritance in Caenorhabditis elegans
铂金血统：一种用于基因变异的长读基准	Kronenberg, Z.	PDF	N/A	The Platinum Pedigree: A long-read benchmark for genetic variants
人乳头瘤病毒（HPV）相关宫颈上皮内瘤变组织的空间分析显示，与宫颈癌进展相关的独特免疫特征。	Pavilion, G. L.	PDF	N/A	Spatial analysis of HPV associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression
蝴蝶大脑在短暂接触信息素后，其形态和基因剪接模式会发生改变。	Dion, E.	PDF	N/A	Butterfly brains change in morphology and in gene splicing patterns after brief pheromone exposure
雄性和雌性小鼠在社会压力诱导的动机方面存在差异性变化	McGraw, M.	PDF	N/A	Divergent changes in social stress-induced motivation in male and female mice
海盗：掠夺AlphaFold预测以自动化蛋白质工程	Richardson, G.	PDF	N/A	PIRATE: Plundering AlphaFold Predictions to Automate Protein Engineering
OpenExo：一款开源模块化外骨骼，用于增强人体功能	Williams, J. R.	PDF	N/A	OpenExo: An Open-Source Modular Exoskeleton to Augment Human Function
通过斜向光热显微镜实现的超灵敏活体红外光谱成像	Li, M.	PDF	N/A	Ultrasensitive in vivo infrared spectroscopic imaging via oblique photothermal microscopy
高通量形态筛选鉴定出化学定义的间充质基质细胞培养基，可增强细胞增殖并支持免疫调节功能的维持。	Spoerer, T. M.	PDF	N/A	High Throughput Morphological Screening Identifies Chemically Defined Media for Mesenchymal Stromal Cells that Enhances Proliferation and Supports Maintenance of Immunomodulatory Function
神经群体方差解释了学习过程中适应性差异	Stealey, H. M.	PDF	N/A	Neural population variance explains adaptation differences during learning
微孔板微加工：一种可定制的平台，支持微生理培养模型的原型设计、开发和测试	Reynolds, J. I.	PDF	N/A	Microplate micromilling: A customizable platform to support the prototyping, development and testing of microphysiological culture models
一项针对具有形态多样解剖结构的人类主动脉CT图像的U-Net三维图像分割研究	Chen, J.	PDF	N/A	A 3D Image Segmentation Study of U-Net on CT Images of the Human Aorta with Morphologically Diverse Anatomy
使用多模态神经网络在多频率谐波运动和B模式成像上进行自动肿瘤和FUS病灶量化	Hu, S.	PDF	N/A	Automated Tumor and FUS Lesion Quantification on Multi-frequency Harmonic Motion and B-mode Imaging Using a Multi-modality Neural Network
一种新的压缩策略，用于减小纳米孔测序数据的大小	Jayasooriya, K.	PDF	N/A	A new compression strategy to reduce the size of nanopore sequencing data
EvoSeq-ML：借助进化信息引导的蛋白质序列表示与生成推进数据中心机器学习	Mardikoraem, M.	PDF	N/A	EvoSeq-ML: Advancing Data-Centric Machine Learning with Evolutionary-Informed Protein Sequence Representation and Generation
利用Spacedust在微生物基因组中发现保守基因簇的新方法	Zhang, R.	PDF	N/A	De novo discovery of conserved gene clusters in microbial genomes with Spacedust
用于冷冻电镜中鲁棒目标检测的新统计度量——2DTM	Zhang, K.	PDF	N/A	New Statistical Metric for Robust Target Detection in Cryo-EM Using 2DTM
两栖动物saxiphilins结合和中和石房蛤毒素同系物的结构基础	Zakrzewska, S.	PDF	N/A	Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins
盐酸胍对胸腺α1和α-突触核蛋白形状的影响截然不同	Liu, Z.	PDF	N/A	Impact of Guanidine Hydrochloride on the shapes of Prothymosin-α and α-Synuclein is dramatically different
照亮根系-土壤力学	Le Houx, J.	PDF	N/A	Illuminating root-soil mechanics
使适配体更具抗体样特性：利用瓶刷聚合物偶联的适配体在体内靶向AXL	Sun, T.	PDF	N/A	Making Aptamers More Antibody-like: Targeting AXL in Vivo Using a Bottlebrush Polymer-Conjugated Aptamer
BoMBR：一个用于网状纤维分割的骨髓活检数据集	Raina, P.	PDF	N/A	BoMBR: An Annotated Bone Marrow Biopsy Dataset for Segmentation of Reticulin Fibers
黄瓜花叶病毒的sRNA调节症状影响桃蚜的取向和取食行为	Wrzesinska-Krupa, B.	PDF	N/A	Symptom-modulating satRNAs of cucumoviruses affect the orientation and feeding behaviour of Myzus persicae
癌胚蛋白Nogo-A通过VEGF-Notch-Hippo-代谢信号通路限制人源和鼠源胶质瘤的血管化和生长	Schwab, M.	PDF	N/A	Onco-fetal protein Nogo-A restricts human and mouse glioma vascularization and growth via VEGF-Notch-hippo-metabolic signaling
运动想象提高老年和年轻女性的力量控制能力	Calkins, C. A.	PDF	N/A	Motor Imagery Improves Force Control in Older and Young Females
大鼠下丘脑和未定带（Zona Incerta）的化学构筑研究。Chemopleth 1.0，一个可下载的交互式脑图空间数据库，包含五个可同时可视化的神经化学系统，并配备了新颖的特征和基于网格的映射工具。	Navarro, V. I.	PDF	N/A	Chemoarchitectural studies of the rat hypothalamus and zona incerta.Chemopleth 1.0, a downloadable interactive Brain Maps spatial database of five co-visualizable neurochemical systems, with novel feature- and grid-based mapping tools
通过无偏细胞类型分布聚类揭示的大脑结构组织	Munoz-Castaneda, R.	PDF	N/A	Brain Structural Organization Revealed by Unbiased Cell-Type Distribution Clustering
通过交叉验证多尺度多模态数据，重建小鼠大脑中单个神经元的连接组	Xiong, F.	PDF	N/A	Reconstruct a Connectome of Single Neurons in Mouse Brains by Cross-Validating Multi-Scale Multi-Modality Data
药物增强慢波活动可改善认知功能并减少阿尔茨海默病小鼠模型早期阶段的淀粉样病变。	Kollarik, S.	PDF	N/A	Pharmacological enhancement of slow-wave activity improves cognition and reduces amyloidosis at an early stage in a mouse model of Alzheimer's disease
自上而下的反馈很重要：类脑连接模式对视听整合的功能影响	Tugsbayar, M.	PDF	N/A	Top-down feedback matters: Functional impact of brainlike connectivity motifs on audiovisual integration
多实验室研究确立了在人工生态系统中进行植物微生物组研究的可靠方法	Novak, V.	PDF	N/A	Multi-laboratory Study Establishes Reproducible Methods for Plant-Microbiome Research in Fabricated Ecosystems
微小RNA和RNA结合蛋白介导的转录后调控对于早期胚胎细胞命运的决定至关重要。	Sangokoya, C.	PDF	N/A	Coordinate post-transcriptional regulation by microRNAs and RNA binding proteins is critical for early embryonic cell fate decisions
季节性接触和迁徙结构影响宽吻海豚的群体性流行病，并为疫情准备提供信息。	Collier, M. A.	PDF	N/A	Seasonal contact and migration structure mass epidemics and inform outbreak preparedness in bottlenose dolphins
干旱啮齿动物在转录组和基因组层面的趋同适应	Chalopin, D.	PDF	N/A	Convergent transcriptomic and genomic adaptation in xeric rodents
解开水损失与呼吸之间普遍权衡关系的塑料机制	Assis, B. A.	PDF	N/A	Plastic mechanisms for unraveling a universal trade-off between water loss and respiration
G4mer：一种RNA语言模型，用于从群体规模的遗传数据中识别转录组范围内的G-四链体和疾病变异	Zhuang, F.	PDF	N/A	G4mer: An RNA language model for transcriptome-wide identification of G-quadruplexes and disease variants from population-scale genetic data
秀丽隐杆线虫的LON-1蛋白需要其CAP结构域来实现调节身体大小和BMP信号传导的功能。	Serrano, M. V.	PDF	N/A	The C. elegans LON-1 protein requires its CAP domain for function in regulating body size and BMP signaling
系统性实证评估个体碱基编辑靶点：验证USH2A中的治疗靶点及方法比较	Tachida, Y.	PDF	N/A	Systematic empirical evaluation of individual base editing targets: validating therapeutic targets in USH2A and comparison of methods
染色质模型比较与验证的挑战：来自第一届国际4D Nucleome黑客马拉松的项目	Kubica, J.	PDF	N/A	The challenge of chromatin model comparison and validation a project from the first international 4D Nucleome Hackathon
宿主基因组驱动虾微生物群的多样性、丰富性和有益微生物：一种全基因组视角。	Cornejo-Granados, F.	PDF	N/A	Host Genome Drives the Diversity, Richness, and Beneficial Microbes in the Shrimp Microbiota: A Hologenome Perspective.
人类血液白细胞成分在呼吸道病毒接种后反应的时间高分辨率图谱	Zhang, Y.	PDF	N/A	Temporal High-Resolution Atlas of Human Blood Leukocyte Composition in Response to Respiratory Virus Inoculation
多细胞生物中单细胞增强子活性的空间重建	Alberti, B.	PDF	N/A	Spatial reconstruction of single-cell enhancer activity in a multicellular organism
结合纳米液滴成像与超声定位显微技术用于检测脑内出血	LIN, B.-Z.	PDF	N/A	Combined Nanodrops Imaging and Ultrasound Localization Microscopy for Detecting Intracerebral Hemorrhage
支链氨基酸（BCAA）组装成有毒纤维丝可能与枫糖尿症（MSUD）的发病机制有关。	Kanth, C. P.	PDF	N/A	Assembly of branched chain amino acid (BCAA) to toxic fibrils may be related to pathogenesis of Maple syrup urine disease (MSUD)
基于级联向量化的化合物-蛋白质相互作用预测模型	Williams, G.	PDF	N/A	A Predictive Model for Compound-Protein Interactions Based on Concatenated Vectorization
消除病毒知识以实现安全且负责任地预测变异效果	Li, M.	PDF	N/A	Unlearning Virus Knowledge Toward Safe and Responsible Mutation Effect Predictions
CellEKT：一种稳健的化学蛋白质组学工作流程，用于分析激酶抑制剂的细胞靶点参与情况	Ruegger, J.	PDF	N/A	CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors
微小标签（Microbetag）：通过注释、富集测试和代谢互补分析简化微生物网络解释	Zafeiropoulos, H.	PDF	N/A	microbetag: simplifying microbial network interpretation through annotation, enrichment tests and metabolic complementarity analysis
从随机动力学和时空模式中学习机器学习稀疏反应扩散模型	Abubaker-Sharif, B.	PDF	N/A	Machine learning sparse reaction-diffusion models from stochastic dynamics and spatiotemporal patterns
遮荫对美国佛罗里达群岛加勒比海八放珊瑚Briareum asbestinum行为生态的影响	Draud, S. L.	PDF	N/A	Influence of Shading on the Behavioral Ecology of a Caribbean Alcyonacean Octocoral, Briareum asbestinum, in the Florida Keys, United States
利用碱性磷酸酶（AP）免疫标记方法研究fms样酪氨酸激酶3（FLT3）及其他神经元蛋白的细胞及亚细胞分布特征	Yin, Y.	PDF	N/A	Characterization of the cellular and subcellular distribution of fms-like tyrosine kinase 3 (FLT3) and other neuronal proteins using an alkaline phosphatase (AP) immunolabeling method
血清素增强神经发生生物标志物、海马体积和阿尔茨海默病中的认知功能	Azargoonjahromi, A.	PDF	N/A	Serotonin Enhances Neurogenesis Biomarkers, Hippocampal Volumes, and Cognitive Functions in Alzheimer's Disease
跨任务含义：海马事件边界反应如何预测无关的记忆表现	van Dijk, D.	PDF	N/A	Cross-task implications: How hippocampal event boundary responses predict unrelated memory performance
利用高扩散加权强度增强的结构脑连接分析	Yu, L.	PDF	N/A	Enhanced Structural Brain Connectivity Analyses Using High Diffusion-weighting Strengths
刺激历史，而非预期，驱动了哺乳动物大脑皮层中的感觉预测误差。	Westerberg, J. A.	PDF	N/A	Stimulus history, not expectation, drives sensory prediction errors in mammalian cortex
Tbc1d15 在体内的敲低通过促进自噬减轻了 α-突触核蛋白诱导的神经毒性。	Siddiqi, F. H.	PDF	N/A	Tbc1d15 knockdown in vivo alleviates α-synuclein-induced neurotoxicity by promoting autophagy.
推进适应性细胞疗法：优化适应性自然杀伤细胞在实体瘤中的扩增	Almazan, N. M.	PDF	N/A	Advancing Adoptive Cell Therapy: Optimized Expansion of Adaptive NK Cells for Solid Tumors
在抗逆转录病毒治疗的人类免疫缺陷病毒（HIV）感染者中，结肠CD8+ T细胞中PPARγ的下调导致上皮屏障破坏。	Das Adhikari, U.	PDF	N/A	PPARγ downregulation in colonic CD8+ T cells results in epithelial barrier disruption in people with HIV on antiretroviral therapy
IL-1β信号在人类淋巴组织中调节T滤泡辅助细胞和调节性T细胞	Vaineau, R.	PDF	N/A	IL-1β Signaling Modulates T Follicular Helper and Regulatory Cells in Human Lymphoid Tissues
通过宏基因组学洞察伊利湖中金属和抗生素抗性基因的时空变化	Reddy, S.	PDF	N/A	Metagenomic Insights into the Spatio-temporal Variation of Metal and Antibiotic Resistance Genes in Lake Erie
首个多用途的猫冠状病毒反向遗传系统	Kida, I.	PDF	N/A	First versatile reverse genetics system for feline coronavirus
skalo：使用SKA分割k-mers与着色de Brujin图进行插入缺失基因分型	Derelle, R.	PDF	N/A	skalo: using SKA split k-mers with coloured de Brujin graphs to genotype indels
甘油提高了冷冻保存领鞭虫的存活率。	Chandra, S.	PDF	N/A	Glycerol improves the viability of a cryopreserved choanoflagellate
基于栖息地面积和状况的指标并不能很好地反映无脊椎动物的生物多样性。	Duffus, N. E.	PDF	N/A	Metrics based on habitat area and condition are poor proxies for invertebrate biodiversity
两种热带果蝇同时入侵沙漠环境中的差异与趋同性	Elsabrout, A.	PDF	N/A	Divergence and parallelism in two tropical drosophilids simultaneously invading a desert environment
雌性异配甲基组中的剂量补偿与性冲突	Tangili, M.	PDF	N/A	Dosage compensation and sexual conflict in female heterogametic methylomes
了解普通秋沙鸭的遗传多样性和系统地理学，及其在克什米尔喜马拉雅湿地中与其他水鸟物种的系统发育关系。	Ahmad, K.	PDF	N/A	Understanding genetic diversity and phylogeography of Common Teal and its phylogenetic relationship with other water bird species in the wetlands of Kashmir Himalayas.
爱德华兹珊瑚爱德华西亚·埃莱根斯的新基因组	Rutlekowski, A.	PDF	N/A	De-novo Genome of the Edwardsiid anthozoan Edwardsia elegans
解码胶原蛋白的热诱导展开和重折叠途径	Al-Shaer, A.	PDF	N/A	Decoding Collagen's Thermally Induced Unfolding and Refolding Pathways
Cdv蛋白之间的相互作用层次结构驱动其招募至膜颈区域	De Franceschi, N.	PDF	N/A	Interaction hierarchy among Cdv proteins drives recruitment to membrane necks
整合可持续有机纳米酶与现场传感平台，实现农业与生物分子双重检测	Lee, D. H.	PDF	N/A	Consolidated sustainable organic nanozyme integrated with Point-Of-Use sensing platform for dual agricultural and biological molecule detection
ChIPbinner：一个用于分析ChIP-Seq或CUT&RUN/TAG数据中在均匀窗口内分箱的广义组蛋白标记的R包	Padilla, R.	PDF	N/A	ChIPbinner: An R package for analyzing broad histone marks binned in uniform windows from ChIP-Seq or CUT&RUN/TAG data
空间多组学的马赛克整合与SpaMosaic	Yan, X.	PDF	N/A	Mosaic integration of spatial multi-omics with SpaMosaic
全双曲神经网络：一种研究衰老轨迹的新方法	Ramirez, H.	PDF	N/A	Fully Hyperbolic Neural Networks: A Novel Approach to Studying Aging Trajectories
创建：通过离散嵌入识别细胞类型特异的顺式调控元件	Cui, X.	PDF	N/A	CREATE: cell-type-specific cis-regulatory elements identification via discrete embedding
Gas1介导的肝母细胞瘤肿瘤发生抑制	Chen, K.	PDF	N/A	Gas1-Mediated Suppression of Hepatoblastoma Tumorigenesis
BaMBo：一个用于分割任务的带注释骨髓活检数据集	Singh, A.	PDF	N/A	BaMBo: An Annotated Bone Marrow Biopsy Dataset for Segmentation Task
GRIN2B疾病相关突变破坏了BK通道和NMDA受体信号纳米域的功能	Martinez-Lazaro, R.	PDF	N/A	GRIN2B disease-associated mutations disrupt the function of BK channels and NMDA receptor signalling nanodomains
埃塞俄比亚中南部地区小麦叶枯病菌群体的遗传多样性	Tucho, A.	PDF	N/A	Genetic Diversity of Zymoseptoria tritici Populations in Central and South-eastern Ethiopia
可调节低速率的基因组重组与大肠杆菌中的Cre-lox系统：合成生物学和环境感知的通用工具	Garabello, E.	PDF	N/A	Tunable Low-Rate Genomic Recombination with Cre-lox in E. coli: A Versatile Tool for Synthetic Biology and Environmental Sensing
少突胶质细胞利用突触后蛋白来协调在不同神经递质类别的轴突上形成髓鞘。	Carey, N.	PDF	N/A	Oligodendrocytes use post-synaptic proteins to coordinate myelin formation on axons of distinct neurotransmitter classes
Fms样激酶3（FLT3）的药理学抑制促进了神经元的成熟并在小鼠模型中抑制了癫痫发作。	Cruite, K.	PDF	N/A	Pharmacological inhibition of Fms-like kinase 3 (FLT3) promotes neuronal maturation and suppresses seizure in a mouse model
脉冲神经网络的最优控制	Costa, T.	PDF	N/A	Optimal control of spiking neural networks
一种靶向膜的光开关在退化的视网膜中恢复了对光的生理开/关响应	Benfenati, F.	PDF	N/A	A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina
Pannexin-2 缺陷的斑马鱼表现出眼部和视觉运动行为缺陷。	Shanbhag, R.	PDF	N/A	Pannexin-2 deficient zebrafish develop ocular and visual motor behaviour defects
一种用于相关分析的热塑性芯片，结合了免疫细胞反应的筛选与高分辨率成像	van Ooijen, H.	PDF	N/A	A thermoplastic chip for correlative assays combining screening and high-resolution imaging of immune cell responses
初始CD4+ T细胞库的异质性与可塑性	Sajani, A.	PDF	N/A	Heterogeneity and plasticity of the naive CD4+ T cell compartment
智利高盐湖中的后生动物多样性通过环境DNA被揭示	Sacco, M.	PDF	N/A	Metazoan diversity in Chilean hypersaline lakes unveiled by environmental DNA
EDTA试管适用于在资源有限的环境中进行胰岛素和C肽的检测，并且可以在室温下保存长达24小时。	Nathan, M.	PDF	N/A	EDTA tubes are suitable for insulin and C-peptide measurement in resource-limited settings and can be stored at room temperature for up to 24 hours
衣藻中淀粉颗粒的形成不需要淀粉合酶4同工型。	COURSEAUX, A.	PDF	N/A	Starch granule initiation doesnt require a starch synthase 4 isoform in Chlamydomonas reinhardtii.
推进无创机械通气：模拟技术提升呼吸护理效果	Tahmid, M. T.	PDF	N/A	Advancing Noninvasive Mechanical Ventilation:Simulating Techniques for Improved Respiratory Care
情感调节障碍儿童的奖励加工	Aggensteiner, P. M.	PDF	N/A	Reward processing in children with Affective Dysregulation
Theta-gamma经颅交流电刺激增强健康年轻和老年人的运动技能习得	Gamage, N. N.	PDF	N/A	Theta-gamma transcranial alternating current stimulation enhances motor skill acquisition in healthy young and older adults
中间神经元特化的命运可塑性	Mostajo-Radji, M. A.	PDF	N/A	Fate plasticity of interneuron specification
性别化的肠道和口腔微生物群变化：揭示胰腺癌中的性别特异性菌群失调	Khan, Z. A.	PDF	N/A	Genderized Gut and Oral Microbiome Shifts: Uncovering Sex-Specific Dysbiosis in Pancreatic Cancer
免疫肽组学助力结核分枝杆菌MHC-II抗原的发现与疫苗设计中的应用	Leddy, O.	PDF	N/A	Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design
肠道微生物对原发性硬化性胆管炎-炎症性肠病模型中结肠炎及结肠炎相关癌变的影响	Awoniyi, M.	PDF	N/A	Gut Microbial Impact on Colitis and Colitis-Associated Carcinogenesis in a Primary Sclerosing Cholangitis-IBD Model
构建一个社区驱动的生物信息学平台，以促进大麻（Cannabis sativa）多组学研究	Mansueto, L.	PDF	N/A	Building a community-driven bioinformatics platform to facilitate Cannabis sativa multi-omics research
一种改进的TEAD显性负性蛋白抑制剂，用于研究Hippo YAP1/TAZ依赖性转录。	Branch, B.	PDF	N/A	An improved TEAD dominant-negative protein inhibitor to study Hippo YAP1/TAZ-dependent transcription.
CellStudio：一种模块化、可调节且易获取的平台，用于分析细胞培养中生长因子的分泌	Azuaje-Hualde, E.	PDF	N/A	CellStudio: a Modular, Tunable and Accessible Platform for Analysis of Growth Factors Secretions in Cell Cultures
蜂鸟上喙弯曲作为适应花蜜采食的进化特征	Rico-Guevara, A.	PDF	N/A	Upper bill bending as an adaptation for nectar feeding in hummingbirds
STAMP：通过成像进行单细胞转录组分析和多模态表征	Pitino, E.	PDF	N/A	STAMP: Single-Cell Transcriptomics Analysis and Multimodal Profiling through Imaging
一个针对环境16S rRNA牛津纳米孔测序数据分析的优化参考数据库	Philip, M.	PDF	N/A	A Targeted Reference Database for Improved Analysis of Environmental 16S rRNA Oxford Nanopore Sequencing Data
实时时空追踪传染病在封闭环境中的爆发情况，采用宿主-病原体基于代理的系统	Srinivasan, S.	PDF	N/A	Real-Time Spatiotemporal Tracking of Infectious Outbreaks in Confined Environments with a Host-Pathogen Agent-Based System
模拟溶质回火2	Stratmann, D.	PDF	N/A	Simulated Solute Tempering 2
血液生化改变及由北西埃塞俄比亚贡达ELFORA屠宰场宰杀绵羊的捻转血矛线虫病引起的病变特征	Malede, B. A.	PDF	N/A	Haematobiochemical Alterations and Lesion Characterization Induced by Haemonchosis in Sheep Slaughtered at Gondar ELFORA Abattoir, North West Ethiopia
在人类、动物和婴儿配方奶粉中检测钛纳米颗粒	Rivard, C.	PDF	N/A	Detection of titanium nanoparticles in human, animal and infant formula milk
饮食中的脂质主要沉积在皮肤中，并迅速影响其隔热性能。	Riley, N.	PDF	N/A	Dietary lipid is largely deposited in skin and rapidly affects insulating properties
揭示间充质干细胞外泌体中的miRNAs在慢性酒精摄入引起的神经炎症和行为障碍中的作用	Mellado, S.	PDF	N/A	Unveiling the role of miRNAs from MSC-EVs in neuroinflammation and behavioral impairments induced by chronic alcohol consumption
深度学习和分析模型在健康和精神分裂症的大脑结构-功能关系上给出了不同的结果。	Cai, Q.	PDF	N/A	Deep-learning and analytical models give distinct results for the brain structure-function relationship in health and in psychosis
HBN-EEG：健康大脑网络（HBN）脑电图数据集的FAIR实现	Shirazi, S. Y.	PDF	N/A	HBN-EEG: The FAIR implementation of the Healthy Brain Network (HBN) electroencephalography dataset
探索脑机接口中深度学习与可解释模型之间的权衡	Cubillos, L. H.	PDF	N/A	Exploring the trade-off between deep-learning and explainable models for brain-machine interfaces
内质网相关受体SorCS1-3的胞内结构域中存在一个三丝氨酸基序，该基序调控神经营养活性。	Dalby, A.	PDF	N/A	A triple serine motif in the intracellular domains of sortilin-related receptors SorCS1-3 regulates neurotrophic activity
通过混合前额叶皮层资源实现动态注意力控制	Di Bello, F.	PDF	N/A	Dynamic Attentional Control Through Mixed Prefrontal Cortex Resources
血清蛋白质组学揭示了通过追踪SARS-CoV2混合免疫对关注变异的高亲和力和趋同抗体	Patel, A.	PDF	N/A	Serum proteomics reveals high-affinity and convergent antibodies by tracking SARS-CoV2 hybrid immunity to emerging variants of concern
加纳大塔马利都市区牛、牛肉及人类中沙门氏菌肠炎的基因组分析	Sunmonu, G. T.	PDF	N/A	Genomic Analysis of Salmonella enterica from cattle, beef and humans in the Greater Tamale Metropolis of Ghana
人类星状病毒感染的新型小鼠模型揭示了其对心血管系统的趋向性	Owen, M. C.	PDF	N/A	Novel murine model of human astrovirus infection reveals a cardiovascular tropism
微重力和低量缪子辐射影响秀丽隐杆线虫中的病毒致病性和生理学	Villena-Gimenez, A.	PDF	N/A	Microgravity and low muon radiation affect viral pathogenesis and physiology in Caenorhabditis elegans
检测自北方短尾鼩（Blarina brevicauda）的新型副亨尼帕病毒	Imai, S.	PDF	N/A	Detection of a novel parahenipavirus from northern short-tailed shrews (Blarina brevicauda )
延迟的病毒清除和改变的炎症反应导致老年小鼠SARS-CoV-2感染的严重性增加。	Lacasse, E.	PDF	N/A	Delayed viral clearance and altered inflammatory responses resulted in increased severity of SARS-CoV-2 infection in aged mice.
一种具有分离活性的双功能snoRNA，能够指导rRNA的2'-O-甲基化并作为配子发生效应器的支架	Leroy, E.	PDF	N/A	A bifunctional snoRNA with separable activities in guiding rRNA 2'-O-methylation and scaffolding gametogenesis effectors
脂肪酸去饱和作用指导细胞在铁死亡和细胞衰老之间的决策	Kuehnemann, C.	PDF	N/A	Fatty acid desaturation guides cellular decisions between ferroptosis and cellular senescence
衰老肌肉中肌原纤维大小、形状和网络连接的变化	Ajayi, P. T.	PDF	N/A	Changes in Myofibril Size, Shape, and Network Connectivity in Aging Muscle
在再生过程中，VEGF信号在非血管组织的扩展中发挥着进化上保守的作用。	Savage, A. M.	PDF	N/A	An evolutionarily conserved role for VEGF signaling in the expansion of non-vascular tissue during regeneration.
使用光谱流式细胞术对全细胞中核组蛋白H3的翻译后修饰进行分析	Golden, C. S.	PDF	N/A	Nuclear Histone H3 Post-translational Modification Profiling in Whole Cells using Spectral Flow Cytometry
大豆锈病菌（Phakopsora pachyrhizi）的遗传多样性主要由两个主要的进化谱系所驱动。	Rocha, V. D. d.	PDF	N/A	The genetic diversity of the soybean rust pathogen Phakopsora pachyrhizi has been driven by two major evolutionary lineages
基因与环境相互作用及美洲小鼠适应性体型变异	Mack, K. L.	PDF	N/A	Gene-by-environment interactions and adaptive body size variation in mice from the Americas
蚂蚁嗅觉系统的祖先复杂性和受限多样化	Marty, S.	PDF	N/A	Ancestral complexity and constrained diversification of the ant olfactory system
辐鳍鱼类非视觉和视觉视蛋白基因谱系的演化	Policarpo, M.	PDF	N/A	Evolution of the non-visual and visual opsin gene repertoire in ray-finned fishes
性选择在遗传拯救中起着重要作用，但生产力的益处会随着时间而减弱；一项多代实验为保护工作提供信息。	West, G.	PDF	N/A	Sexual selection matters in genetic rescue, but productivity benefits fade over time; a multi-generation experiment to inform conservation.
性别和遗传背景影响混合大鼠多样性面板中的静脉注射羟考酮自我给药	Duffy, E. P.	PDF	N/A	Sex and genetic background influence intravenous oxycodone self-administration in the Hybrid Rat Diversity Panel
锥虫线粒体基因组分离复合体永久性外-内膜接触位点的分子特征	Stettler, P.	PDF	N/A	Molecular characterization of the permanent outer-inner membrane contact site of the mitochondrial genome segregation complex in trypanosomes
MDA5变异体对自身免疫性疾病保护作用的分子基础	Singh, R.	PDF	N/A	Molecular basis of autoimmune disease protection by MDA5 variants
使用小分子方法对RNA鸟嘌呤-7甲基转移酶（RNMT）进行表征	Pearson, L.-A.	PDF	N/A	Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach
具有序列控制骨架的瓶刷聚合物，用于增强寡核苷酸递送	Wei, Y.	PDF	N/A	Bottlebrush polymers with sequence-controlled backbones for enhanced oligonucleotide delivery
PoreMeth2：利用纳米孔测序解码甲基化组变化的演化	Mattei, G.	PDF	N/A	PoreMeth2: decoding the evolution of methylome alterations with Nanopore sequencing
HLAIIPred：用于建模HLA II类分子与肽段相互作用的交叉注意力机制	Haghighatlari, M.	PDF	N/A	HLAIIPred: Cross-Attention Mechanism for Modeling the Interaction of HLA Class II Molecules with Peptides
PUNCH2：探索内在无序蛋白质预测器的策略	Meng, D.	PDF	N/A	PUNCH2: explore the strategy for Intrinsically Disordered Protein predictor
Tannin1（高粱中拟南芥主调控因子TTG1的直系同源基因）的多效性调控功能丧失	Schuh, A.	PDF	N/A	Loss of pleiotropic regulatory functions in Tannin1, the sorghum ortholog of Arabidopsis master regulator TTG1
估算英格兰西南部野生鹿群中结核病（牛分枝杆菌）感染的抗体流行率	Jinks, R.	PDF	N/A	Estimating the seroprevalence of tuberculosis (Mycobacterium bovis) infection in a wild deer population in southwest England
摆脱单个神经元的束缚：神经元在神经元集合中的选择性发生变化，其重构是动态编码的基础。	Londei, F.	PDF	N/A	Out of the single-neuron straitjacket: neurons within assemblies change selectivity and their reconfiguration underlies dynamic coding
在转基因小鼠模型中限制听力损失	Babola, T. A.	PDF	N/A	Limiting hearing loss in transgenic mouse models
升高的NAD+通过Sir2A介导的GCβ去乙酰化和OES定位，促进疟原虫卵形体的滑行运动和蚊媒感染	Shi, Y.	PDF	N/A	Elevated NAD+ drives Sir2A-mediated GCβ deacetylation and OES localization for Plasmodium ookinete gliding and mosquito infection
肺上皮细胞稳态和免疫失调加剧了中东呼吸综合征冠状病毒疾病的严重性	Sheahan, T. P.	PDF	N/A	Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East Respiratory Syndrome coronavirus disease severity
外显子转录组rRNA指纹分析揭示了组织来源和肿瘤特异性特征	Milenkovic, I.	PDF	N/A	Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures
UBR4调控依赖于MetAP2的精氨酸/N-降解途径	Morrison, E. J.	PDF	N/A	UBR4 regulates a MetAP2-dependent Arg/N-degron pathway
TECPR2是一种Rab5效应器，调控内吞体货物再循环。	Paul, S.	PDF	N/A	TECPR2 is a Rab5 effector that regulates endosomal cargo recycling
脂滴靶向ABHD5和PNPLA3 I148M是促进肝脏脂肪变性所必需的	Teskey, G.	PDF	N/A	Lipid Droplet Targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis
同时测量总氧进化和基础光合作用氧化还原反应：以蓝细菌为例的研究	Liran, O.	PDF	N/A	Simultaneous Measurement of Gross Oxygen Evolution and Underlying Photosynthetic Redox Reactions: A Case Study Using Cyanobacteria
DYRK1A激酶三倍体是唐氏综合征中中耳炎的主要病因。	Tateossian, H.	PDF	N/A	DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome
具有改变的RNA结合和降解活性的病理性PNPase变体影响细菌和人类细胞模型的表型。	Pizzoccheri, R.	PDF	N/A	Pathological PNPase variants with altered RNA binding and degradation activity affect the phenotype of bacterial and human cell models
通过13个物种的基因组和功能注释进行长链非编码RNA（lncRNA）的跨物种直系同源检测。	Degalez, F.	PDF	N/A	Cross-species orthology detection of long non-coding RNAs (lncRNA) through 13 species using genomic and functional annotations.
使用ONT R10.4.1长读长测序技术对三种主要呼吸道细菌病原体进行精确基因分型	Zidane, N.	PDF	N/A	Accurate genotyping of three major respiratory bacterial pathogens with ONT R10.4.1 long-read sequencing
使用蛋白质语言模型进行单序列、无结构的变构残基预测	Kannan, G. R.	PDF	N/A	Single-Sequence, Structure Free Allosteric Residue Prediction with Protein Language Models
高盐极端微生物核糖体分析中微球菌核酸酶（MNase）的纯化	Gregorova, P.	PDF	N/A	Purification of micrococcal nuclease (MNase) for use in ribosomal profiling of high-salinity extremophiles
揭示肽核酸作为Riboglow RNA成像平台功能连接体的潜力	Wierzba, A. J.	PDF	N/A	Unveiling the Promise of Peptide Nucleic Acids as Functional Linkers for Riboglow RNA Imaging Platform
表面非对称机械阻抗下步行的前向模拟：步态康复的启示	Abdikadirova, B.	PDF	N/A	Forward Simulations of Walking on Surfaces with Asymmetric Mechanical Impedance: Insights for Gait Rehabilitation
蛋白质语言模型的适应性取决于偏好	Gordon, C.	PDF	N/A	Protein Language Model Fitness Is a Matter of Preference
LIET模型：捕捉从加载到终止的RNA聚合酶动力学	Stanley, J. T.	PDF	N/A	LIET Model: Capturing the kinetics of RNA polymerase from loading to termination
在重构系统中20种氨酰-tRNA合成酶的可持续再生，迈向自合成人工系统	Hagino, K.	PDF	N/A	Sustainable Regeneration of 20 Aminoacyl-tRNA Synthetases in a Reconstituted System Toward Self-Synthesizing Artificial Systems
高通量优化基于纸张的无细胞生物传感器	Garcia, D. C.	PDF	N/A	High-Throughput Optimization of Paper-Based Cell-Free Biosensors
巨细胞病毒通过核输出宿主限制因子DDX41来限制先天免疫反应	Baruah, V.	PDF	N/A	Cytomegalovirus Restricts the Innate Immune Response by Nuclear Export of Host Restriction Factor DDX41
通过整合系统发育信息，从微生物基因组中改进最大生长速率预测	Xu, L.	PDF	N/A	Improved maximum growth rate prediction from microbial genomes by integrating phylogenetic information
在丁香假单胞菌中，IS5元件的独立、持续的支系特异性扩张	Baltrus, D. A.	PDF	N/A	Independent, Ongoing Clade-Specific Expansions of IS5 Elements in Pseudomonas syringae
微生物群落的稳定性与珊瑚的热耐受性相关	Baquiran, J. I. P.	PDF	N/A	Microbiome stability is linked to coral thermotolerance
含水层微生物群落在热砷迁移作用下表现出高度变异性。	Chen, M.	PDF	N/A	Aquifer microbial communities are highly variable in response to thermal arsenic mobilization
通过光在哺乳动物细胞中表达生物治疗药物的强效光开关	Gebel, J.	PDF	N/A	Potent photoswitch for expression of biotherapeutics in mammalian cells by light
百年博物馆标本病毒宏基因组学揭示了RNA的长期稳定性	Keene, A. H.	PDF	N/A	Viral metagenomics of 100-year-old museum specimens highlights the long-term stability of RNA
考察早期儿童功能性和结构性脑网络架构、年龄与注意力技能之间的关系	Rokos, L.	PDF	N/A	Examining Relationships between Functional and Structural Brain Network Architecture, Age, and Attention Skills in Early Childhood
引导视觉搜索与早期视觉皮层中的基于特征的优先图相关联。	Duecker, K.	PDF	N/A	Guided Visual Search is associated with a feature-based priority map in early visual cortex
语义维度支持物体记忆性的皮层表征	Slayton, M. A.	PDF	N/A	Semantic Dimensions Support the Cortical Representation of Object Memorability
母亲-儿童互动中的同步性：神经与运动耦合作为学龄前儿童运动学习与发展的机制	Nagy, P.	PDF	N/A	Interpersonal Synchronization in Mother-Child Dyads: Neural and Motor Coupling as a Mechanism for Motor Learning and Development in Preschoolers
皮层中间神经元对浅层感觉处理的可靠性受行为状态的调节	Sweeney, C. G.	PDF	N/A	Reliable sensory processing of superficial cortical interneurons is modulated by behavioral state
细胞类型特异的投射模式促进皮层微电路中的平衡活动	Kurth, A. C.	PDF	N/A	Cell-type specific projection patterns promote balanced activity in cortical microcircuits
# BioRxiv 2024-10-02 Papers

标题	作者	PDF链接	代码仓库	Title
MSRP6中一个不寻常的转运域定义了一个复杂结构，该结构对于在感染恶性疟原虫的红细胞中锚定和维持Maurer氏裂隙是必需的。	Blancke Soares, A.	PDF	N/A	An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells
一种基于数据的方法，用于建立细胞运动模式作为巨噬细胞亚型及其与细胞形态关系的预测指标	Kesapragada, M.	PDF	N/A	A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology
E4F1 协调丙酮酸代谢与延伸因子复合物的活性，以确保大脑发育过程中翻译的准确性。	DiMichele, M.	PDF	N/A	E4F1 COORDINATES PYRUVATE METABOLISM AND THE ACTIVITY OF THE ELONGATOR COMPLEX TO ENSURE TRANSLATION FIDELITY DURING BRAIN DEVELOPMENT
簇大小决定人类细胞中转录工厂的形态	Semeraro, M.	PDF	N/A	Cluster size determines morphology of transcription factories in human cells
抑郁症中的扣带回前下功能连接异常：脑成像大数据与经颅磁刺激精准引导个性化干预的启示	Chen, X.	PDF	N/A	Subgenual Anterior Cingulate Cortex Functional Connectivity Abnormalities in Depression: Insights from Brain Imaging Big Data and Precision-Guided Personalized Intervention via Transcranial Magnetic Stimulation
构建泛基因组图谱	Garrison, E.	PDF	N/A	Building pangenome graphs
一种可推广的计算机制，揭示了瞬时渴望与决策之间的相互作用	Kulkarni, K. R.	PDF	N/A	A generalizable computational mechanism underlying the interaction between momentary craving and decision-making
通过代谢建模实现基于组学的单细胞真核光合生物功能特征定义	Burel, M.	PDF	N/A	Towards an omics-based definition of unicellular eukaryote phototrophs functional traits via metabolic modelling
CD24+CD271+黑色素瘤癌症干细胞具有其单标记对应物的混合特征，并促进侵袭和治疗抗性。	Knowles, O.	PDF	N/A	A CD24+CD271+ Melanoma Cancer Stem Cell Possesses Hybrid Characteristics of its Single Marker Counterparts and Promotes Invasion and Therapeutic Resistance
在急性刚地弓形虫感染期间，转铁蛋白受体1对于CD4+ T细胞的铁依赖性反应是必需的。	Denton, S. L.	PDF	N/A	Transferrin Receptor 1 is Required for CD4+ T Cell Iron-Dependent Response During Acute Toxoplasma gondii Infection
分形睡眠周期：一种基于非周期性活动的新型睡眠周期定义	Rosenblum, Y.	PDF	N/A	Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles
精子竞争强度塑造了啮齿动物中精子形态和生殖基因的分化	Kopania, E. E. K.	PDF	N/A	Sperm competition intensity shapes divergence in both sperm morphology and reproductive genes across murine rodents
在老鼠的上丘中，循环电路编码了视觉中心-周围计算。	Cui, P.	PDF	N/A	Recurrent circuits encode visual center-surround computations in the mouse superior colliculus
通过时间共享光学镊子微流变学测量细胞器、细胞和生物体的年龄依赖性粘弹性特性	Catala-Castro, F.	PDF	N/A	Measuring age-dependent viscoelastic properties of organelles, cells and organisms via Time-Shared Optical TweezerMicrorheology
MiRGraph：一种混合深度学习方法，通过整合异质调控网络和基因组序列来识别微RNA-靶标相互作用	Liu, P.	PDF	N/A	MiRGraph: A hybrid deep learning approach toidentify microRNA-target interactions by integrating heterogeneous regulatory network and genomic sequences
AptaDiff：基于扩散模型的适配体从头设计与优化	Wang, Z.	PDF	N/A	AptaDiff: de novo design and optimization of aptamers based on diffusion models
同步呼吸：社会行为如何影响宽吻海豚的呼吸道传染病风险	Collier, M. A.	PDF	N/A	Breathing in sync: how a social behavior structures respiratory epidemic risk in bottlenose dolphins
磁性细菌的逃逸问题 - 生理磁场强度有助于磁性细菌在模拟沉积物中导航	Codutti, A.	PDF	N/A	Escape problem of magnetotactic bacteria - physiological magnetic field strengths help magnetotactic bacteria navigate in simulated sediments
努力驱动扫视选择	Koevoet, D.	PDF	N/A	Effort Drives Saccade Selection
在骨质疏松比格犬模型中使用rhPTH(1-34)和二聚体R25CPTH(1-34)增强骨再生和骨整合	Shin, J.-O.	PDF	N/A	Enhancing Bone Regeneration and Osseointegration using rhPTH(1-34) and Dimeric R25CPTH(1-34) in an Osteoporotic Beagle Model
一统天下？评估可持续森林管理指标在多分类数据下对生物多样性保护的表现	Paillet, Y.	PDF	N/A	One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation
宿主基因型在世代间积极塑造其微生物群	Benga, L.	PDF	N/A	The host genotype actively shapes its microbiome across generations
马索科湖慈鲷生态型分化过程中重组景观的快速进化	Talbi, M.	PDF	N/A	Rapid evolution of recombination landscapes during the divergence of cichlid ecotypes in Lake Masoko
违反预测增强了视觉特征在感知中的表征忠实度	Rideaux, R.	PDF	N/A	Violated predictions enhance the representational fidelity of visual features in perception
大规模基因组测序研究中的高效存储与回归计算	Rivas, M. A.	PDF	N/A	Efficient storage and regression computation for population-scale genome sequencing studies
配体耦合的环核苷酸门控离子通道中的构象变化通过时间分辨过渡金属离子FRET揭示	Eggan, P.	PDF	N/A	Ligand-Coupled Conformational Changes in a Cyclic Nucleotide-Gated Ion Channel Revealed by Time-Resolved Transition Metal Ion FRET
使用信息先验来解决存在鉴定错误的占用模型中的识别性问题	Monchy, C.	PDF	N/A	Using informative priors to account for identifiability issues in occupancy models with identification errors
一种用于慢性脊髓神经调节的主动式电子、高密度硬膜外电极阵列	Parker, S. R.	PDF	N/A	An active electronic, high-density epidural paddle array for chronic spinal cord neuromodulation
动物社会网络结构驱动因素的因果框架	Kawam, B.	PDF	N/A	A causal framework for the drivers of animal social network structure
噬菌体展示技术助力机器学习发现癌症抗原特异性T细胞受体	Croce, G.	PDF	N/A	Phage display enables machine learning discovery of cancer antigen specific TCRs
前额叶和感觉皮层中的预备性注意模板编码了与目标相关的信息。	Zhou, Z.	PDF	N/A	Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information
骨髓空间转录组学揭示了多发性骨髓瘤细胞结构，伴有功能障碍的T细胞分布、中性粒捕获和中炎性信号传导	Sudupe, L.	PDF	N/A	Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling
选择性烟碱型乙酰胆碱受体亚型的共激活是逆转阿尔茨海默病中海马网络功能障碍和防止恐惧记忆丧失所必需的。	Lee, R.	PDF	N/A	Co-activation of selective nicotinic acetylcholine receptor subtypes is required to reverse hippocampal network dysfunction and prevent fear memory loss in Alzheimer's disease
HERMES：用于突变效应和稳定性预测的全息等变神经网络模型	Visani, G. M.	PDF	N/A	HERMES: Holographic Equivariant neuRal network model for Mutational Effect and Stability prediction
人类PIEZO1的结构及其缓慢失活的通道病突变体	Shan, Y.	PDF	N/A	Structure of human PIEZO1 and its slow inactivating channelopathy mutants
在RNA分子池中实现基因组信息的稳定复制	Burger, L.	PDF	N/A	Toward Stable Replication of Genomic Information in Pools of RNA Molecules
12-脂氧合酶抑制剂可抑制胰岛免疫和炎症反应，并延缓人基因替代小鼠的自身免疫性糖尿病进展。	Nargis, T.	PDF	N/A	12-Lipoxygenase Inhibition Suppresses Islet Immune and Inflammatory Responses and Delays Autoimmune Diabetes in Human Gene Replacement Mice
贝叶斯分层模型用于决策标准在试验间波动的研究	Vloeberghs, R.	PDF	N/A	A Bayesian Hierarchical Model of Trial-to-Trial Fluctuations in Decision Criterion
工程合成激动剂用于靶向激活Notch信号传导	Perez, D. H.	PDF	N/A	Engineering synthetic agonists for targeted activation of Notch signaling
eduWOSM：一款专为教育和研究设计的高级台式显微镜	Carter, N. J.	PDF	N/A	The eduWOSM: a benchtop advanced microscope for education and research
在不同癌症类型中，以单细胞分辨率和空间背景下解析长链非编码RNA的多样性	Prakrithi, P.	PDF	N/A	Unraveling lncRNA Diversity at a Single Cell Resolution and in a Spatial Context across Different Cancer Types
小鼠中导致dRTA的SLC4A1突变引起的尿钠丢失和集合管功能紊乱	Mungara, P.	PDF	N/A	Urinary Sodium Wasting and Disrupted Collecting Duct Function in Mice with dRTA-Causing SLC4A1 Mutations
RNA的替代性解码在哺乳动物中产生了稳定且丰富的蛋白质	Tsour, S.	PDF	N/A	Alternate RNA decoding results in stable and abundant proteins in mammals
肌钙蛋白C突变体中的钙结合亲和力：自由能计算、协同进化建模与机器学习	Pooja,	PDF	N/A	Calcium Binding Affinity in the Mutational Landscape of Troponin-C: Free Energy Calculation, Coevolution modeling and Machine Learning
适用于快速培养阴道细菌（如惰性乳酸杆菌）及其他阴道细菌的实用培养基配方	Serrador, D.	PDF	N/A	Practical Media Formulations for Rapid Growth of Lactobacillus iners and Other Vaginal Bacteria
CD11B+CD36+细胞是促进骨形成的巨噬细胞，能够限制与年龄相关的骨质流失。	Koroth, J.	PDF	N/A	CD11B+CD36+ cells are bone anabolic macrophages that limit age-associated bone loss
行为控制的多巴胺基础	Ballard, I. C.	PDF	N/A	A dopaminergic basis of behavioral control
在斑马鱼神经杆内局部激活光遗传学NMYII会导致远距离、不对称的力传播。	Crellin, H. A.	PDF	N/A	Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation
一个统一的啮齿动物图谱揭示了背侧迷走复合体的细胞复杂性和进化分歧	Hes, C.	PDF	N/A	A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex
用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱系统	Bazargan, S.	PDF	N/A	A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets
已撤回：酒石黄无法使活体组织透明化	Inagaki, S.	PDF	N/A	WITHDRAWN: Tartrazine cannot make live tissues transparent
鉴定出利什曼原虫中一种新型基体定位的ε-微管蛋白	Seth, A.	PDF	N/A	Identification of a novel basal body-localized epsilon-tubulin in Leishmania
预测透析器选择和吸附剂透析液流速对胆红素清除的影响	Novokhodko, A.	PDF	N/A	Predicting the Impact of Dialyzer Choice and Binder Dialysate Flow Rate on Bilirubin Removal
实时预测药物诱导的致心律失常风险，采用性别特异性的心脏模拟器	Dominguez-Gomez, P.	PDF	N/A	Real-time prediction of drug-induced proarrhythmic risk with sex-specific cardiac emulators
开发高效且选择性的CK1α分子胶降解剂	Geng, Q.	PDF	N/A	Development of potent and selective CK1α Molecular Glue Degraders
运动皮层编码运动学习的神经景观中的分离吸引子	Liu, X.	PDF	N/A	Separated attractors in neural landscape of motor cortex encoding motor learning
人类协作中的可控性与因果关系	Spiering, L.	PDF	N/A	Controllability and cause in human collaboration
表观基因组分析揭示了H3K27me3调控人类皮层发育中外基质成分的组成	Ditzer, N.	PDF	N/A	Epigenome profiling identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis
宿主特异性决定了新的真菌植物病原体种群的出现	C. Fagundes, W.	PDF	N/A	Host specialization defines the emergence of new fungal plant pathogen populations
快速两步靶标捕获确保了高效的CRISPR-Cas9引导的基因组编辑	Shi, H.	PDF	N/A	Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing
藿香蓟（Agastache rugosa (Fisch. & C.A.Mey.) Kuntze）的综合生理可塑性揭示了对光和养分梯度的复杂适应性	Rosli, K. A.	PDF	N/A	Integrative physiological plasticity of Agastache rugosa (Fisch. & C.A.Mey.) Kuntze reveals complex adaptation to light and nutrient gradients
在运动规划中的高效编码	Wang, T.	PDF	N/A	Efficient Coding in Motor Planning
一种敏感的红/远红光开关，用于在小鼠代谢疾病模型中可控的基因治疗	Qiao, L.	PDF	N/A	A sensitive red/far-red photoswitch for controllable gene therapy in mouse models of metabolic diseases
捏合与拇指和食指屈曲过程中皮层表面电位的空间和光谱变化	Kerezoudis, P.	PDF	N/A	Spatial and Spectral Changes in Cortical Surface Potentials during Pinching versus Thumb and Index Finger Flexion
一种新开发的全基因组测序方案使得早期追踪肠道病毒D68的分子进化成为可能。	Giardina, F. A.	PDF	N/A	A newly developed whole genome sequencing protocol enables early tracking of Enterovirus D68 molecular evolution.
开发一种新型方法制备高功能人类浦肯野网络	Ji, P.	PDF	N/A	Development of a Novel Method to Fabricate Highly Functional Human Purkinje Networks
肠道微生物群与2型糖尿病关联：16s研究及其方法学挑战的元分析	Machado, J.	PDF	N/A	Gut microbiota and type 2 diabetes associations: A meta-analysis of 16s studies and their methodological challenges
乳腺癌中FABP4和FABP5的表达特征：临床意义与展望	Li, B.	PDF	N/A	Expression Profiles of FABP4 and FABP5 in Breast Cancer: Clinical Implications and Perspectives
五人制足球游戏训练对青春期非运动员女孩表现、自我效能、动机及运动成瘾的影响	Beik, S.	PDF	N/A	Effect of Futsal-Based Game Training on Performance, Self-Efficacy, Motivation, and Exercise Addiction in Adolescent Non-Athlete Girls
将空间扩散纳入突发性随机转录模型中	Miles, C. E.	PDF	N/A	Incorporating spatial diffusion into models of bursty stochastic transcription
使用二维和三维图像分析工具对成年小鼠脑样本中微胶质细胞形态复杂性进行比较分析	Murray, C. J.	PDF	N/A	A comparison of microglial morphological complexity analysis in adult mouse brain samples using 2-dimensional and 3-dimensional image analysis tools
使用单细胞和单核测序技术进行可扩展电路映射的高复杂度条形码狂犬病病毒	Shin, D.	PDF	N/A	High-Complexity Barcoded Rabies Virus for Scalable Circuit Mapping Using Single-Cell and Single-Nucleus Sequencing
长程相互激活在细胞迁移过程中建立Rho和Rac的极性	De Belly, H.	PDF	N/A	Long range mutual activation establishes Rho and Rac polarity during cell migration
效应异质性揭示了罕见编码变异的复杂多效性效应	Lu, W.	PDF	N/A	Effect heterogeneity reveals complex pleiotropic effects of rare coding variants
细胞类型指导的镶嵌性局灶性癫痫基因分型揭示了细胞自主性和非细胞自主性疾病相关转录程序	Bizzotto, S.	PDF	N/A	Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs
鉴定与先天性心脏病中临床报告的CNV相关的长非编码RNA候选疾病基因	Penaloza, J. S.	PDF	N/A	Identification of Long Non-coding RNA Candidate Disease Genes Associated with Clinically Reported CNVs in Congenital Heart Disease
一种综合的蛋白质组和转录组学方法揭示了新的ADAM9底物及其下游通路	Lu, C.	PDF	N/A	An integrative proteotranscriptomics approach reveals new ADAM9 substrates and downstream pathways
先前报道的90万年前人类祖先的瓶颈期很可能是一个统计学上的假象。	Deng, Y.	PDF	N/A	A previously reported bottleneck in human ancestry 900 kya is likely a statistical artifact
重复性头部撞击暴露与慢性创伤性脑病的血浆蛋白质组质询	Saloner, R.	PDF	N/A	Interrogating the plasma proteome of repetitive head impact exposure and chronic traumatic encephalopathy
人口基因组学揭示了非洲本土谷物苔麸（Eragrostis tef）性状改良的位点	Jones, M. R. W.	PDF	N/A	Population genomics uncover loci for trait improvement in the indigenous African cereal tef (Eragrostis tef)
增强型激酶转位报告系统用于同时实时测量PKA、ERK和Ca2+	Tsai, S.-J.	PDF	N/A	Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and Ca2+
调节ATP-腺苷信号轴结合放射治疗促进脑转移中的抗癌免疫	Salamero-Boix, A.	PDF	N/A	Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis
基于细胞提取物的体外DNA复制能够实现可持续的无细胞基因表达	Zheng, X.	PDF	N/A	Cell extract-based in vitro DNA replication enables sustainable cell-free gene expression
扩展莱茵衣藻倍性操作工具箱	Van de Vloet, A.	PDF	N/A	Expanding the toolkit for ploidy manipulation in Chlamydomonas reinhardtii
布尔网络吸引子景观的映射	Trinh, V.-G.	PDF	N/A	Mapping the attractor landscape of Boolean networks
小鼠背侧梨状皮层核的全脑连接和新奇反应	Manjila, S. B.	PDF	N/A	Brain-wide connectivity and novelty response of the dorsal endopiriform nucleus in mice
经验塑造了嗅觉表征沿着皮层-海马路径的转变	Eleonore, S.	PDF	N/A	Experience shapes the transformation of olfactory representations along the cortico-hippocampal pathway
B细胞c-Maf信号在胰腺癌和黑色素瘤的动物模型中促进肿瘤进展	Zhong, Q.	PDF	N/A	B cell c-Maf signaling promotes tumor progression in animal models of pancreatic cancer and melanoma
SIRT4通过增强NK细胞对肝星状细胞的细胞毒性，并通过AMPKα/P-p53/NKG2DL途径逆转肝纤维化。	Zhang, F.	PDF	N/A	SIRT4 enhances the cytotoxicity of NK cells toward hepatic stellate cells and reverses liver fibrosis via AMPKα/P-p53/NKG2DL pathway
RNA结合蛋白Musashi1与病毒基因组RNA相互作用，并通过抑制翻译来限制SARS-CoV-2感染。	Ganguli, S.	PDF	N/A	RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation
阿塔卡马沙漠的土壤生物多样性在不同多样性水平上呈现出明显的模式。	Villegas, L.	PDF	N/A	Soil biodiversity in the Atacama Desert shows distinct patterns at different diversity levels
使用对比学习进行遗传数据降维	Thor, F.	PDF	N/A	Dimensionality Reduction of Genetic Data using Contrastive Learning
酵母中的rDNA拷贝数变异会改变对环境条件的响应	Thornton, K.	PDF	N/A	rDNA copy number variation in yeast alters response to environmental conditions
质子通道失活导致叶绿体NDH复合物活性丧失	Strand, D. D.	PDF	N/A	Proton channel inactivation results in loss of chloroplast NDH complex activity
持续接触多价抗原修饰的纳米颗粒会产生广泛的抗冠状病毒反应。	Baillet, J.	PDF	N/A	Sustained exposure to multivalent antigen-decorated nanoparticles generates broad anti-coronavirus responses
单细胞核测序揭示肾上腺皮质癌中的复制应激	Popova, L. V.	PDF	N/A	Single Nuclei Sequencing Reveals Replication Stress in Adrenocortical Carcinoma
来自中国新疆上侏罗纪齐古组的新剑龙（恐龙纲：鸟臀目）及其对中国剑龙类系统发育的修订	Li, N.	PDF	N/A	A new stegosaur (Dinosauria: Ornithischia) from the Upper Jurassic Qigu Formation of Xinjiang, China and a revision on Chinese stegosaurs phylogeny
神经分化型内皮细胞亚型调控器官血流与免疫平衡	Gyarmati, G.	PDF	N/A	Neuronally differentiated endothelial cell subtype regulates organ blood flow and immune balance
基于合成细胞的组织用于自下而上组装人工淋巴器官	Burgstaller, A.	PDF	N/A	Synthetic cell-based tissues for bottom-up assembly of artificial lymphatic organs
利用多模态网络数据整合与分析解码帕金森病变异体间的共享分子失调	Zagare, A.	PDF	N/A	Deciphering shared molecular dysregulation across Parkinson's disease variants using a multi-modal network-based data integration and analysis
海洋杜父鱼配对鳍上的表皮微结构为支撑底栖固着机制提供了新的见解。	Kane, E. A.	PDF	N/A	Epidermal microstructures on the paired fins of marine sculpins provide new insights into mechanisms supporting benthic station-holding
多重功能分析TAP2变体在调节MHC-I细胞表面丰度中的作用揭示了PLK1的过度表达下调抗原呈递。	Nagy, G.	PDF	N/A	Multiplexed functional analysis of TAP2 variants in regulating MHC-I cell surface abundance reveals overexpression of PLK1 downregulates antigen presentation.
增加CPT1a表达是对病理应激的关键心脏保护性反应，它抑制了重塑基因程序，并使通过基因转移进行拯救成为可能。	Carley, A. N.	PDF	N/A	Increased CPT1a expression is a critical cardioprotective response to pathological stress that suppresses gene programs for remodeling and enables rescue by gene transfer
癫痫的破伤风毒素模型中突触异质性降低：计算模型提供的见解	Zarei Eskikabd, P.	PDF	N/A	Reduced Synaptic Heterogeneity in a Tetanus ToxinModel of Epilepsy: Insights from ComputationalModeling
在高度视觉化的动物中，通过注视远程激活地点代码	Payne, H. L.	PDF	N/A	Remote activation of place codes by gaze in a highly visual animal
神经代谢物T1弛豫时间的年龄依赖性	Murali-Manohar, S.	PDF	N/A	Age dependency of neurometabolite T1 relaxation times
自噬增强剂在额颞叶痴呆的干细胞模型中挽救了Tau蛋白的积累	Mirfakhar, F.	PDF	N/A	Autophagic enhancer rescues Tau accumulation in a stem cell model of frontotemporal dementia
循环蛋白塑造小胶质细胞状态并增强吞噬作用	Lu, N.	PDF	N/A	Circulatory proteins shape microglia state and boost phagocytosis
单细胞RNA测序揭示了小鼠和大鼠母体向合子过渡的早期转录程序	Su, Y.	PDF	N/A	Single-cell RNA-seq Reveals Early Transcriptional Programs of the Maternal to Zygote Transition in Mice and Rats
各向异性拉伸使多细胞水螅聚集体中的肌动蛋白纤维自组织产生偏倚	Bailles, A.	PDF	N/A	Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates
一种可持续且由蜜蜂授粉的咖啡，为你的一天拉开序幕	Alves, D. A.	PDF	N/A	A sustainable and bee-pollinated coffee to start your day
新生代进化史掩盖了棘鳍鱼类在中生代的起源。	Brownstein, C. D.	PDF	N/A	Cenozoic evolutionary history obscures the Mesozoic origins of acanthopterygian fishes
在极端代谢适应下的三维基因组组织表现出基因组区室化和环状结构的变化。	Biswas, T.	PDF	N/A	3D genome organization under extreme metabolic adaptation shows variations in genome compartmentalization and looping
一种新的古菌遗传密码的零星分布，其中所有TAG密码子均编码吡咯赖氨酸	Kivenson, V.	PDF	N/A	Sporadic distribution of a new archaeal genetic code with all TAG codons as pyrrolysine
分析桉油精、柠檬烯和蒎烯肠溶胶囊（QIENUO）治疗肺囊性纤维化的分子机制：网络药理学研究与分子对接验证	Tiantaixi, T.	PDF	N/A	Analyzing the Molecular Mechanism of Eucalyptol, Limonene and Pinene Enteric Capsules (QIENUO) in the Treatment of Pulmonary cystic fibrosis with Network Pharmacology and Verifying Molecular Docking
通过整合序列和结构特征，增强蛋白质功能身份的预测	Fujita, S.	PDF	N/A	Enhanced prediction of protein functional identity through the integration of sequence and structural features
突变型IDH使p53与靶基因调控分离，从而抑制肿瘤抑制功能	Martin, C. P.	PDF	N/A	Mutant IDH uncouples p53 from target gene regulation to disable tumor suppression
通过罗望子果实果肉乙醇提取物减轻氟化钠处理对Wistar大鼠生殖功能的抑制作用	Usman, L. A.	PDF	N/A	Mitigation of Reproductive Function in Sodium Fluoride-administered Wistar Rats by Tamarindus indica Fruit Pulp Ethanol Extract
探索新领域：一种新型Cdk5抑制剂恢复认知功能并缓解2型糖尿病	Paul, S.	PDF	N/A	Exploring New Horizons:A Novel Cdk5 Inhibitor Restoring Cognitive Function and Alleviating Type 2 Diabetes.
社会性塑造了支持低氧耐受性的线粒体适应	Rossi, A.	PDF	N/A	Sociality shapes mitochondrial adaptations supporting hypoxia tolerance
内皮下钙化增加表面粗糙度，并促进脂质沉积到动脉壁中。	Kosciuszek, N. D.	PDF	N/A	Subendothelial Calcification Increases Surface Roughness and Promotes Lipid Deposition into the Arterial Wall
后顶叶皮层调节前额眼区中的内在神经时间尺度和注意处理	Soyuhos, O.	PDF	N/A	Posterior Parietal Cortex Regulates Intrinsic Neural Timescales and Attentional Processing in Frontal Eye Field
SARM1的缺失可防止常染色体显性视神经萎缩中的视网膜神经节细胞退化。	Ding, C.	PDF	N/A	Loss of SARM1 protects against retinal ganglion cell degeneration in Autosomal Dominant Optic Atrophy
Galnt2神经元丢失损害O-糖基化并导致模拟GALNT2-CDG的神经行为缺陷	Edmondson, A. C.	PDF	N/A	Neuronal loss of Galnt2 Impairs O-glycosylation and Leads to Neurobehavioral Deficits Mimicking GALNT2-CDG
前丘脑中与心率相关的活动在相位性和紧张性快速眼动睡眠期间有所不同。	Simor, P.	PDF	N/A	Heartbeat related activity in the anterior thalamus differs between phasic and tonic REM sleep periods
双特异性磷酸酶3（Dual Specificity Phosphatase 3）的敲低促使髓系白血病细胞分化为巨噬细胞并极化。	Farias, J. O.	PDF	N/A	Dual Specificity Phosphatase 3 knockdown drives myeloid leukemia cells to differentiate into macrophages and polarize
人胰腺导管类器官中的旋转迁移依赖于肌动蛋白和肌球蛋白的活性。	Xie, G.	PDF	N/A	Rotational migration in human pancreatic ductal organoids depends on actin and myosin activity
评估跨平台归一化方法以进行综合微阵列和RNA测序数据分析	Sun, X.	PDF	N/A	Evaluating Cross-Platform Normalization Methods for Integrated Microarray and RNA-seq Data Analysis
微通道内增强的细菌趋化性：在通道宽度与圆形游泳半径匹配时达到最佳性能	Yue, C.	PDF	N/A	Enhanced bacterial chemotaxis in confined microchannels: Optimal performance in lane widths matching circular swimming radius
年龄相关性的PDE11A4蛋白表达增加会触发酶的液-液相分离（LLPS），而这种相分离可以通过PDE11A4小分子抑制剂逆转。	Amurrio, E.	PDF	N/A	Age-related increases in PDE11A4 protein expression trigger liquid:liquid phase separation (LLPS) of the enzyme that can be reversed by PDE11A4 small molecules inhibitors
认知控制中的前摄、反应和注意动态的计算建模	Mistry, P. K.	PDF	N/A	Computational Modeling of Proactive, Reactive, and Attentional Dynamics in Cognitive Control
FB5P-seq-mAbs：从FB5P-seq库中制备单克隆抗体，用于B细胞的整合单细胞分析	Ado, S.	PDF	N/A	FB5P-seq-mAbs: monoclonal antibody production from FB5P-seq libraries for integrative single-cell analysis of B cells
Spc105-Kre28复合体通过外侧动粒招募Ipl1/Aurora B激酶促进有丝分裂错误校正	Dudziak, A.	PDF	N/A	The Spc105-Kre28 complex promotes mitotic error correction by outer kinetochore recruitment of the Ipl1/Aurora B kinase
UBR-1缺乏导致C. elegans对伊维菌素的抗性	Li, Y.	PDF	N/A	UBR-1 deficiency leads to ivermectin resistance in C. elegans
拓扑异构酶2B和核纤层B受体协同调控基因组与核纤层相互作用	Manzo, S. G.	PDF	N/A	Coordinated control of genome-nuclear lamina interactions by Topoisomerase 2B and Lamin B receptor
IgBlend：在抗体语言模型中统一三维结构和序列	Malherbe, C.	PDF	N/A	IgBlend: Unifying 3D Structures and Sequences in Antibody Language Models
基于模拟的推断中更优的置信区间	Rousset, F.	PDF	N/A	Better confidence intervals in simulation-based inference
微缩图：无监督地将多重组织成像数据集的缩略图作为数据门户的预览	Taylor, A. J.	PDF	N/A	Miniature: Unsupervised glimpses into multiplexed tissue imaging datasets as thumbnails for data portals
PHLOWER - 使用Hodge拉普拉斯分解进行单细胞轨迹分析	Cheng, M.	PDF	N/A	PHLOWER - Single cell trajectory analysis using Decomposition of the Hodge Laplacian
LINE-1核糖核蛋白复合物通过与DNA结合，在有丝分裂期间促进核内进入。	Zernia, S.	PDF	N/A	LINE-1 ribonucleoprotein complexes bind DNA to enable nuclear entry during mitosis
探究烃类交联剂对p53钉合肽结构及结合能力的影响	Choudhury, A. R.	PDF	N/A	Exploring the effect of Hydrocarbon Cross-linkers on the Structure and Binding of Stapled p53 Peptides
N-乙酰-2-氨基芴（AAF）：通过来自多周期肝致癌性喂养方案的癌前肝细胞原代培养，揭示了生长周期依赖性大分子结合常数KD的体内时间表达模式	Koch, K. S.	PDF	N/A	N-Acetyl-2-Aminofluorene (AAF): In vivo temporal expression patterns of growth cycle-dependent macromolecular binding constants KD are revealed by primary cultures of premalignant hepatocytes derived from a multi-cyclic hepatocarcinogenic feeding regimen
通过动力学分类实现可调的配体辨别	Dixit, P. D.	PDF	N/A	Tunable ligand discrimination via kinetic sorting
单细胞通过“异或”和“不等于”逻辑在二聚体中识别非自我与自我	An, R.	PDF	N/A	Single Cells Signal Non-self from Self via 'XOR' and 'NOT EQUALS' Logic in a Dimer of Dimers
使用肌电图进行可泛化的手势识别	Yun, R.	PDF	N/A	Generalizable gesture recognition usingmagnetomyography
利用肌电图进行可泛化的手势识别	Yun, R.	PDF	N/A	Generalizable gesture recognition usingmagnetomyography
快速眼动睡眠期间θ频带活动的时空模式：一项脑磁图分析	Provias, V.	PDF	N/A	Spatiotemporal patterns of theta-band activity during rapid-eye movement sleep: a magnetoencephalography analysis
在Dravet综合征的小鼠模型中，表达Parvalbumin的中间神经元的异位动作电位发放显著减弱。	Hill, S. F.	PDF	N/A	Attenuated ectopic action potential firing in parvalbumin expressing interneurons in a mouse model of Dravet Syndrome
使用各向同性ADC-fMRI技术绘制人脑灰质和白质活动图	Spencer, A. P. C.	PDF	N/A	Mapping grey and white matter activity in the human brain with isotropic ADC-fMRI
一项针对与精神分裂症相关基因的果蝇筛选研究强调了神经和胶质细胞中的基质金属蛋白酶在神经重塑中的必要性。	Keret, S.	PDF	N/A	A Drosophila screen of schizophrenia-related genes highlights the requirement of neural and glial matrix metalloproteinases for neuronal remodeling
自适应时空框架用于自动E/MEG源成像	Feng, Z.	PDF	N/A	STARTS: A self-adapted spatio-temporal framework for automatic E/MEG source imaging
历史偏差及其对猕猴前额叶皮层刺激表征的扰动。	Benozzo, D.	PDF	N/A	History bias and its perturbation of the stimulus representation in the macaque prefrontal cortex.
利用牵张反射模型从肌电图（EMG）中估计快速和慢速运动中的下行激活模式	Zhang, L.	PDF	N/A	Estimating descending activation patterns from EMG in fast and slow movements using a model of the stretch reflex
使用自动编码器生成信号和ResNet分类的脑刺激伪影鲁棒检测	Saal, J.	PDF	N/A	Robust Detection of Brain Stimulation Artifacts in iEEG Using Autoencoder-Generated Signals and ResNet Classification
多样化的钙动力学支撑着海马CA1锥体细胞中位置场的形成	Sumegi, M.	PDF	N/A	Diverse calcium dynamics underlie place field formation in hippocampal CA1 pyramidal cells
验证运动校正后的MPRAGE与常规MPRAGE在儿童形态学分析中的一致性	Gal-Er, B.	PDF	N/A	Verifying the concordance between motion corrected and conventional MPRAGE for pediatric morphometric analysis
计算建模揭示了神经生物学对静态和动态功能连接模式的贡献	Hoheisel, L.	PDF	N/A	Computational modelling reveals neurobiological contributions to static and dynamic functional connectivity patterns
稳定的Netrin-1荧光报告鸡揭示了视裂闭合过程中细胞特异性的分子特征。	Chan, B. H. C.	PDF	N/A	A stable Netrin-1 fluorescent reporter chicken reveals cell-specific molecular signaturesduring optic fissure closure.
林地驯鹿在危险栖息地的社会促进作用：对火灾和道路的反应	Hendrix, J. G.	PDF	N/A	Social facilitation of risky habitats in woodland caribou: responses to fire and roads
对存在采样强度偏差和删失的动物网络进行稳健贝叶斯分析	Sosa, S.	PDF	N/A	Robust Bayesian analysis of animal networks subject to biases in sampling intensity and censoring
竞争排斥、基于经验的学习以及人类捕捞活动，对幼年及成年褐鹈鹕（Pelecanus occidentalis）的活动模式产生影响。	Plazas-Cardona, D.	PDF	N/A	Competitive exclusion, experience-based learning, and human fishing, influence activity patterns in Juvenile and Adult Brown Pelicans (Pelecanus occidentalis)
通过异质OATP-配体相互作用图神经网络（HOLI-GNN）预测OATP1B1抑制剂	Mardikoraem, M.	PDF	N/A	Predicting Inhibitors of OATP1B1 via Heterogeneous OATP-Ligand Interaction Graph Neural Network (HOLI-GNN)
三维微结构的快速原型制作：一种简化的灰度光刻编码方法，使用Blender软件实现	Borghi, F. F.	PDF	N/A	Rapid Prototyping of 3D Microstructures: A Simplified Grayscale Lithography Encoding Method Using Blender
利用工程化病毒样颗粒进行活细胞转录组学	Najia, M. A.	PDF	N/A	Live-cell transcriptomics with engineered virus-like particles
ClassiCOL：通过胶原蛋白肽模糊性进行古代物种分类的LC-MS/MS分析	Engels, I.	PDF	N/A	ClassiCOL: LC-MS/MS analysis for ancient species Classification via Collagen peptide ambiguation
关于残基D1-V185在Synechocystis 6803和Thermosynechococcus vestitus中光系统II功能中的作用的新见解。	BOUSSAC, A.	PDF	N/A	New insights into the involvement of residue D1-V185 in Photosystem II function in Synechocystis 6803 and Thermosynechococcus vestitus.
mTOR信号通过3'UTR介导的翻译控制促进T细胞中的细胞因子产生	Jurgens, A. P.	PDF	N/A	mTOR signaling promotes cytokine production in T cells through 3UTR-mediated translation control
阴道毛滴虫胞外囊泡抑制IFNϵ介导的对宿主细胞溶解的保护作用	Kochanowsky, J. A.	PDF	N/A	Trichomonas vaginalis extracellular vesicles suppress IFNϵ-mediated protection against host cell cytolysis
凝胶内重折叠使得在SDS-PAGE后能够对完全变性的GFP进行荧光检测。	Shiratori, M.	PDF	N/A	In-gel refolding allows fluorescence detection of fully denatured GFPs after SDS-PAGE
G4停滞的CMG的冷冻电镜结构揭示了DNA易位的尺蠖机制	Batra, S.	PDF	N/A	Cryo-EM structures of G4-stalled CMG reveal inchworm mechanism of DNA translocation
致癌蛋白TEL-ABL的自磷酸化使其对变构ABL抑制剂阿西米尼产生耐药性。	Muratcioglu, S.	PDF	N/A	Autophosphorylation of the oncogenic protein TEL-ABL confers resistance to the allosteric ABL inhibitor asciminib
工程化合成多价VHH抗体识别SARS-Cov-2刺突蛋白的结构基础	Lujan Hernandez, A. G.	PDF	N/A	Structural basis of SARS-Cov-2 spike recognition by engineered synthetic multivalent VHH antibodies
一种经过工程改造的染色质蛋白，增强了其对H3K27me3相对于H3K9me3的优先结合能力	Franklin, K. A.	PDF	N/A	An engineered chromatin protein with enhanced preferential binding of H3K27me3 over H3K9me3
利用冈比亚按蚊密度病毒（AgDNV）内含子表达系统表达冈比亚按蚊内源性微小RNA	Johnson, R. M.	PDF	N/A	Expression of endogenous Anopheles gambiae microRNAs using an Anopheles gambiae densovirus (AgDNV) intronic expression system
软X射线断层扫描揭示了在tasA缺失后B.subtilis生物膜结构的变异	Chatzimpinou, A.	PDF	N/A	Soft X-ray tomography reveals variations in B.subtilis biofilm structure upon tasA deletion
疟原虫运动中的牵引力生成受疟原虫粘附蛋白TLP的调节。	Ripp, J.	PDF	N/A	Traction force generation in motile malaria parasites is modulated by the Plasmodium adhesin TLP
从太平洋牡蛎中分离得到的加利西亚单胞菌（Gallaecimonas pentaromativorans）10A株的基因组显示了其降解碳氢化合物和CRISPR-Cas防御的潜力。	Gouin, Y.	PDF	N/A	The genome of Gallaecimonas pentaromativorans strain 10A, isolated from a Pacific oyster, reveals the potential for hydrocarbon degradation and CRISPR-Cas defense
种间系统生物学将细菌代谢途径与线虫的基因表达、行为和生存联系起来。	Athanasouli, M.	PDF	N/A	Interspecies systems biology links bacterial metabolic pathways to nematode gene expression, behavior, and survival
刚地弓形虫PROP1在慢性感染期间对自噬和寄生虫存活至关重要	Thaprawat, P.	PDF	N/A	Toxoplasma gondii PROP1 is critical for autophagy and parasite viability during chronic infection
土壤深度决定了高粱田中的微生物群落	Murray, E. R.	PDF	N/A	Soil depth determines the microbial communities in Sorghum bicolor fields
核糖体蛋白的过度表达导致大肠杆菌对锌产生抗性	Kosaki, T.	PDF	N/A	Overexpression of Ribosomal Proteins Leads to Zn Resistance in Escherichia coli
内部框架翻译产生Cas11b，这对于古菌CRISPR-Cas系统中的有效干扰至关重要。	Sailer, A.-L.	PDF	N/A	Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system
MukBEF SMC复合物捕获DNA的机制及其被病毒DNA模拟物抑制的机制	Bürmann, F.	PDF	N/A	Mechanism of DNA entrapment by the MukBEF SMC complex and its inhibition by a viral DNA mimic
纳米纹理钢表面具有抗真菌活性	Tripathi, A.	PDF	N/A	Nanotextured steel surface exhibits antifungal activity
环境中的多硫化物促进在厌氧条件下生长的微生物的蛋白质二硫键形成。	Liu, H.	PDF	N/A	Environmental polysulfides promote protein disulfide bond formation of microorganisms growing under anaerobic condition
基因组范围内体内动态的cohesin介导的环挤压及其在转录激活中的作用	Popay, T. M.	PDF	N/A	Genome-wide in vivo dynamics of cohesin-mediated loop extrusion and its role in transcription activation
基于转录组的全基因组范围内鉴定冈比亚按蚊的长非编码RNA（lncRNA）	Xu, J.	PDF	N/A	Transcriptome-based identification of long noncoding RNAs (lncRNAs) across the genome of Anopheles gambiae
综合多组学特征揭示了绝经后人类卵巢中阿霉素诱导的细胞衰老。	Devrukhkar, P. R.	PDF	N/A	A comprehensive multi-omics signature of doxorubicin-induced cellular senescence in the postmenopausal human ovary.
MORC-1是秀丽隐杆线虫（C. elegans）CSR-1生殖系基因许可机制的关键组成部分。	Kirshner, J. A.	PDF	N/A	MORC-1 is a key component of the C. elegans CSR-1 germline gene licensing mechanism
早期干预使用低剂量硬化蛋白抗体治疗可减少卵巢切除大鼠初始骨丢失后由成骨细胞介导的继发性矿化	Naqvi, S. M.	PDF	N/A	Early Intervention with Low-Dose Sclerostin Antibody Therapy can Reduce Osteocyte-mediated Secondary Mineralization after initial bone loss in Ovariectomised Rats
VCP、VCPIP1 和 p47 的三元复合物形成促进了高尔基体的重新组装。	Shah, B.	PDF	N/A	Ternary complex formation of VCP, VCPIP1 and p47 facilitates Golgi reassembly
inPhase - 一种简单、准确且快速的方法来确定蛋白质凝聚相图	Fritsch, A. W.	PDF	N/A	inPhase - A simple, accurate and fast approach to determine phase diagrams of protein condensates
西西米迪蒂斯：具有锌-四半胱氨酸模体和天冬酰胺酰化的RiPPs	Zhu, A.	PDF	N/A	Cysimiditides: RiPPs with a Zn-tetracysteine motif and aspartimidylation
从共同的前生物激活中间体中，肽和RNA的交叉催化增强	Roy, R.	PDF	N/A	Cross-catalytic enhancement of peptides and RNA from a common prebiotic activated intermediate
丘脑室旁核中垂体腺苷酸环化酶激活多肽（PACAP）的过度表达改变了雌性大鼠的动机和情感行为	Carpenter, B. A.	PDF	N/A	Pituitary adenylate cyclase-activating polypeptide (PACAP) overexpression in the paraventricular nucleus of the thalamus alters motivated and affective behavior in female rats
视觉特征注意控制的分层组织	Meyyappan, S.	PDF	N/A	Hierarchical Organization of Visual Feature Attention Control
在思想的连续流动中，自发记忆回忆和未来思考的神经动力学	Su, H.	PDF	N/A	Neural dynamics of spontaneous memory recall and future thinking in the continuous flow of thoughts
致病相关脑膜炎奈瑟菌丝状噬菌体MDA{varphi}的结构	Boehning, J.	PDF	N/A	Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDA{varphi}
Meru 协调纺锤体取向与细胞极性和细胞周期进程	McLellan, M. M.	PDF	N/A	Meru co-ordinates spindle orientation with cell polarity and cell cycle progression
一种用于跨物种小脑发育比较研究的最低限度引导类器官模型	Guglielmi, L.	PDF	N/A	A minimally guided organoid model for cross-species comparisons of cerebellar development
逐步、模块化的均一大脑类器官设计，代表神经元与胶质细胞之间动态的细胞相互作用	Kim, E.	PDF	N/A	A stepwise, modular design of building uniform brain assembloids representing the dynamic cellular interplay between neurons and glial cells
对听觉反馈操作的敏感性和个体差异	Ozker, M.	PDF	N/A	Susceptibility to auditory feedback manipulations and individual variability
导致智力障碍的KIF11基因突变会损害微管动力学和树突分支	Wingfield, J. L.	PDF	N/A	Intellectual disability-causing mutations in KIF11 impair microtubule dynamics and dendritic arborization
纹状体的调节支持特定策略的强化，而非动作选择	Hodge, A. T.	PDF	N/A	Striatal modulation supports policy-specific reinforcement and not action selection
# BioRxiv 2024-10-01 Papers

标题	作者	PDF链接	代码仓库	Title
一项miRNA筛选发现了一个调控成年干细胞命运的转录程序	Robert, J.	PDF	N/A	A miRNA screen identifies a transcriptional program controlling the fate of adult stem cell
Cul3泛素连接酶通过与Insomniac作为适配器相互作用，影响睡眠和突触稳态。	Li, Q.	PDF	N/A	The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis
Swi6/HP1与siRNA-DNA杂交体的H3-K9-me非依赖性结合在小孢子酵母中启动了在同源dg-dh重复序列处的异染色质组装	Singh, J.	PDF	N/A	An H3-K9-me-independent binding of Swi6/HP1 to siRNA-DNA hybrids initiates heterochromatin assembly at cognate dg-dh repeats in Fission Yeast
深度学习和跨物种分析揭示了性别和大麻素信号传导对小脑蚓部形态的影响	Black, K. C.	PDF	N/A	Deep learning and cross-species analysis identify the influences of sex and cannabinoidsignaling on cerebellar vermis morphology
SATB1通过结合到碱基不配对区域（BURs）来组织基因组，为SATB1调控的基因表达提供支架。	Kohwi, Y.	PDF	N/A	Genome organization by SATB1 binding to base-unpairing regions (BURs) provides scaffold for SATB1-regulated gene expression
更年期男性？对果蝇进行的伴侣选择理论实验验证表明，两性都可能经历更年期	Purohith, D.	PDF	N/A	Men in menopause? Experimental verification of the mate choice theory with Drosophila melanogaster shows both sexes can undergo menopause
高曝光度差异使得在小规模甲基汞暴露的秘鲁成年人EWAS中能够检测到候选生物标志物	Weinhouse, C.	PDF	N/A	High exposure variance enables candidate biomarker detection in a small EWAS of methylmercury-exposed Peruvian adults
大鼠非桶状体感皮层的建模与仿真。第一部分：解剖建模	Reimann, M. W.	PDF	N/A	Modeling and Simulation of Rat Non-Barrel Somatosensory Cortex. Part I: Modeling Anatomy
基于模型的压缩感知实现了从全息集合刺激中快速学习神经回路	Triplett, M. A.	PDF	N/A	Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing
全脑范围的突触蛋白周转测量揭示了学习过程中局部可塑性的存在	Mohar, B.	PDF	N/A	Brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning
有其母必有其女？孤雌生殖黄蜂体型表型可塑性、环境协变及遗传力研究	Tovar, A.	PDF	N/A	Like mother, like daughter? Phenotypic plasticity, environmental covariation, and heritability of size in a parthenogenetic wasp
多蛋白信号复合物维持AKT和mTOR/S6K活性，这对处于压力下的癌细胞的生存是必需的。	Teran Pumar, O. Y.	PDF	N/A	A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress
PRDM16在BMP通路中作为共抑制因子，抑制神经干细胞的增殖。	He, L.	PDF	N/A	PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation
预测内在无序蛋白质的序列依赖性骨架动力学	Qin, S.	PDF	N/A	Predicting the Sequence-Dependent Backbone Dynamics of Intrinsically Disordered Proteins
单核细胞毒素引起破坏性的Sec61依赖性内皮糖萼和血管基底膜丧失：结核分枝杆菌感染中驱动组织坏死的新间接机制	Hsieh, L. T.-H.	PDF	N/A	Mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection
全脑血容量变化驱动人类宏观脑脊液流动	Zimmermann, J.	PDF	N/A	Total cerebral blood volume changes drive macroscopic cerebrospinal fluid flux in humans
Detect+Track：用于改进鱼类跟踪和行为分析的稳健且灵活的软件工具	Dutta, A.	PDF	N/A	Detect+Track: Robust and flexible software tools for improved tracking and behavioural analysis of fish
通过从整体到单细胞的反卷积方法，分析白血病干细胞的药物敏感性	Alexandre, C.	PDF	N/A	Profiling drug sensitivity of leukemic stem cells via bulk-to-single-cell deconvolution
代谢网络中切换节点的计算机模拟识别	Mairet, F.	PDF	N/A	In silico identification of switching nodes in metabolic networks
肌动蛋白-TFII-IΔ通过形态力学调节ERK的调谐，调控细胞身份	Wu, Q.	PDF	N/A	Morphomechanic tuning of ERK by actin-TFII-IΔ regulates cell identity
在有限时间内进行高效的数量估计	Heng, J. A.	PDF	N/A	Efficient numerosity estimation under limited time
系统比较了用于表达预测的计算方法	Kernfeld, E.	PDF	N/A	A systematic comparison of computational methods for expression forecasting
结合视频遥测和可穿戴式MEG进行自然主义成像	O'Neill, G. C.	PDF	N/A	Combining video telemetry and wearable MEG for naturalistic imaging
长期光生物调节对小鼠衰老的治疗效果	Ahmet, I.	PDF	N/A	The Therapeutic Effects of Long-term Photobiomodulation on Aging in Mice
推进蛋白质-DNA结合位点预测：整合序列模型与机器学习分类器	Murad, T.	PDF	N/A	Advancing Protein-DNA Binding Site Prediction: Integrating Sequence Models and Machine Learning Classifiers
孕酮通过两个具有PLA2活性的必需共受体诱导减数分裂	Nader, N.	PDF	N/A	Progesterone induces meiosis through two obligate co-receptors with PLA2 activity
Kdm6a和Kdm6b在调节哺乳动物神经再生中的作用	Yang, S.-G.	PDF	N/A	Roles of Kdm6a and Kdm6b in regulation of mammalian neural regeneration
通过依赖泛素化的TEAD降解靶向癌症中的Hippo通路	Pham, T. H.	PDF	N/A	Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
SARS-CoV-2刺突抗体与登革病毒发生交叉反应，并在体外和体内增强感染	Jakhar, K.	PDF	N/A	SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in-vitro and in-vivo
STING 通过 HOIP 介导的 M1 泛素链合成来刺激 NFkB 信号传导	Fischer, T. D.	PDF	N/A	STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NFkB signaling
互助主义者提供的资源增加了对寄生虫的易感性	Yi, E.	PDF	N/A	Mutualist-Provided Resources Increase Susceptibility to Parasites
人类第二视觉区域中颜色、视差和自然纹理的中尺度功能组织与连接性	Ai, H.	PDF	N/A	Mesoscale functional organization and connectivity of color, disparity, and naturalistic texture in human second visual area
优化Niosome制剂以增强细胞应用：与L-α-卵磷脂脂质体的比较案例研究	Cakir, N.	PDF	N/A	Optimizing Niosome Formulations for Enhanced Cellular Applications: A Comparative Case Study with L-α-lecithin Liposomes
一种高效的计算方法，用于生成具有常染色体三体的阳性NIPT样本	Nguyen Huy, T.	PDF	N/A	An Efficient Computational Method to Create Positive NIPT Samples with Autosomal Trisomy
量化分层肌肉相互作用对运动功能的多样化贡献	O'Reilly, D.	PDF	N/A	Quantifying the diverse contributions of hierarchical muscle interactions to motor function
在站立平衡过程中皮质对姿势摇摆的追踪。	Legrand, T.	PDF	N/A	Cortical tracking of postural sways during standing balance.
利用scATAC-seq在不同免疫细胞类型和背景下对eQTL和哮喘风险位点进行功能性表征	Wei, J.	PDF	N/A	Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts
诱导后的幂律行为短暂存在，这有助于区分竞争性随机基因表达模型之间的差异。	Nicoll, A. G.	PDF	N/A	Transient power-law behaviour following induction distinguishes between competing models of stochastic gene expression
在密集混合神经培养物中无偏倚地鉴定细胞身份	De Beuckeleer, S.	PDF	N/A	Unbiased identification of cell identity in dense mixed neural cultures
通过选择性注意动态调节表征轨迹	Zhou, Y.	PDF	N/A	Dynamic Modulation of Representational Trajectories Through Selective Attention
有机大分子在输送珍珠层形成所需钙前体的过程中占据了相当大的比例。	Macias-Sanchez, E.	PDF	N/A	Organic macromolecules transport a significant proportion of the calcium precursor for nacre formation.
基于相关自然统计的高效编码解释的重量错觉	Bays, P.	PDF	N/A	Weight illusions explained by efficient coding based on correlated natural statistics
鸣禽听觉前脑中用于声音交流信号的预测和错误编码	Rudraraju, S.	PDF	N/A	Predictive and error coding for vocal communication signals in the songbird auditory forebrain
基因表达在富含调控基序的基因组区域中的出现与演化	Fuqua, T.	PDF	N/A	The emergence and evolution of gene expression in genome regions replete with regulatory motifs
与阿片类药物使用障碍的大鼠行为模型中的个体差异相关的前额叶皮质中的差异基因表达和染色质可及性	Liu, S. X.	PDF	N/A	Differential gene expression and chromatin accessibility in the medial prefrontal cortex associated with individual differences in rat behavioral models of opioid use disorder
自闭症相关的PTCHD1错义变异体能与SNARE相关蛋白SNAPIN结合，但表现出细胞内运输障碍。	Pastore, S. F.	PDF	N/A	Autism-associated PTCHD1 missense variants bind to the SNARE-associated protein, SNAPIN, but exhibit impaired subcellular trafficking
一种用于评估生物化学领域模型分布外表现的新框架	Fernandez-Diaz, R.	PDF	N/A	A new framework for evaluating model out-of-distribution for the biochemical domain
MixtureFinder：用于系统发育分析的DNA混合模型估计	Ren, H.	PDF	N/A	MixtureFinder: Estimating DNA mixture models for phylogenetic analyses
新兴细菌性植物病原体的多样化；从全球蔓延的穿孔黄单胞菌中获得的见解	Timilsina, S.	PDF	N/A	Diversification of an emerging bacterial plant pathogen; insights from the global spread of Xanthomonas euvesicatoria pv. perforans
饮食调控背外侧纹状体中的沉默突触	Meyers, A. M.	PDF	N/A	Dietary regulation of silent synapses in the dorsolateral striatum
解析轴突转录组图谱：从诱导多能干细胞衍生的皮层神经元中获得的见解及其对运动神经元退化的意义	Xu, J.	PDF	N/A	Unraveling Axonal Transcriptional Landscapes: Insights from iPSC-Derived Cortical Neurons and Implications for Motor Neuron Degeneration
BindCompare：一种新颖的蛋白质-核酸结合分析综合平台	Mahableshwarkar, P.	PDF	N/A	BindCompare: A Novel Integrated protein-nucleic Acid Binding Analysis Platform
CCDC113稳定精子轴丝和头尾耦合装置，以确保男性生育能力	Wu, B.	PDF	N/A	CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility
基于定向进化的配体体内再刺激CAR-T细胞的发现	Grzywa, T.	PDF	N/A	Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells
猕猴V1中上下文调制的依赖性对层间信号流动的影响	Zhu, S.	PDF	N/A	Dependence of Contextual Modulation in Macaque V1 on Interlaminar Signal Flow
高加索侏儒虾虎鱼（Knipowitschia cf. caucasica）染色体水平基因组参考，这是一种新入侵莱茵河的虾虎鱼科外来物种	Schoenle, A.	PDF	N/A	Chromosome level genome reference of the Caucasian dwarf goby Knipowitschia cf. caucasica, a new alien Gobiidae invadingthe River Rhine
社会地位对非洲慈鲷后续求偶和交配活动的影响	Martashvili, A.	PDF	N/A	Effects of social position on subsequent courtship and mating activity in an African cichlid
对500个人类蛋白质域进行定点饱和诱变，揭示了蛋白质失稳对遗传疾病的贡献	Beltran, T.	PDF	N/A	Site saturation mutagenesis of 500 human protein domains reveals the contribution of protein destabilization to genetic disease
利用贝叶斯参数估计与条件变分自编码器识别肌肉中的机制与治疗靶点	Tune, T. C.	PDF	N/A	Identifying mechanisms and therapeutic targets in muscle using Bayesian parameter estimation with conditional variational autoencoders
特定的有丝分裂事件驱动细胞骨架重塑，这是左右器官发育所必需的。	Wu, Y.	PDF	N/A	Specific Mitotic Events Drive Cytoskeletal Remodeling Required for Left-Right Organizer Development
单细胞基因型-表型映射识别VEXAS综合征的治疗脆弱性	Ganesan, S.	PDF	N/A	Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome
瞳孔流形：揭示瞳孔大小相位变化背后的潜在几何结构	Blini, E.	PDF	N/A	Pupillary manifolds: uncovering the latent geometrical structures behind phasic changes in pupil size
植物质外体中的枯草杆菌蛋白酶SBT5.2能灭活鞭毛蛋白的免疫原性	Buscaill, P.	PDF	N/A	Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplast
通过活益生菌细菌刺激，对源自健康人结肠类器官的上皮组织和癌细胞系进行全面的基因表达分析	Sen, A.	PDF	N/A	Comprehensive gene expression analysis of organoid-derived healthy human colonic epithelium and cancer cell line by stimulated with live probiotic bacteria
通过Talin激活β2整合素的分子基础揭示了整合素信号传导的物种特异性机制	Wu, J.	PDF	N/A	Molecular Basis of β2 Integrin Activation by Talin Unveils Species-Specific Mechanisms of Integrin Signaling
进化视角下的观赏金鱼双尾肌肉纤维分布研究	Ota, K.	PDF	N/A	Evolutionary Insights into Muscle Fiber Distribution in the Twin Tails of Ornamental Goldfish
视网膜祖细胞中TET家族基因的遗传缺失会损害光感受器发育并导致失明	Dvoriantchikova, G.	PDF	N/A	Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness
链霉菌天蓝色菌收缩注射系统的功能和激发需要膜蛋白CisA	Casu, B.	PDF	N/A	Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA
小脑作为强化学习机器的尖峰神经网络模型	Kuriyama, R.	PDF	N/A	Spiking network model of the cerebellum as a reinforcement learning machine
利用Coronin 1作为模板，开发基于肽的融合抑制剂作为抗病毒策略	Panda, M. S.	PDF	N/A	Developing peptide-based fusion inhibitors as an antiviral strategy utilizing Coronin 1 as a template
传染性喉气管炎病毒基因组编码一种功能性白细胞介素-4同源物：揭示一种新型毒力因子	Volkening, J. D.	PDF	N/A	A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factor
牙源性和牙周膜间充质中NFATc1+/PDGFR-alpha+细胞的包容性、排他性和层级性图谱	Yang, X.	PDF	N/A	Inclusive, Exclusive and Hierarchical Atlas of NFATc1+/PDGFR-alpha+ Cells in Dental and Periodontal Mesenchyme
疱疹折叠：一种全蛋白质组结构系统方法揭示了所有九种人类疱疹病毒的蛋白质家族和活性	Soh, T. K.	PDF	N/A	HerpesFolds: A proteome-wide structural systems approach reveals insights into protein families and activities of all nine human herpesviruses
大规模实验量化淀粉样核形成使得蛋白质聚集的深度学习可解释	Thompson, M.	PDF	N/A	Massive experimental quantification of amyloid nucleation allows interpretable deep learning of protein aggregation
利用基本再生数量化传播并识别野生动物出血热病毒的数据缺口	Gubbins, S.	PDF	N/A	Using the basic reproduction ratio to quantify transmission and identify data gaps for epizootic haemorrhagic disease virus
用于深入表征纳米颗粒的流式细胞术程序	Tirelli, V.	PDF	N/A	FLOW CYTOMETRIC PROCEDURES FOR DEEP CHARACTERIZATION OF NANOPARTICLES
在IAA16中插入的可转座元件破坏了剪接过程，导致Bassia scoparia对草甘膦产生抗性。	Montgomery, J. S.	PDF	N/A	A transposable element insertion in IAA16 disrupts splicing and causes dicamba resistance in Bassia scoparia
多物种全基因组CRISPR筛选鉴定出冷诱导细胞死亡的保守抑制因子	Lam, B.	PDF	N/A	Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
单亲和多倍体胚细胞的起源与发展	Zhao, Y.	PDF	N/A	Origin and development of uniparental and polyploid blastomeres
双工CeTEAM药物生物传感器揭示了PARP抑制剂选择性的决定因素	Pires, M. J.	PDF	N/A	Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity
多感官诱发电位用于成功分类遗忘型轻度认知障碍的神经机制	Zhang, L.	PDF	N/A	Neural Mechanism Underlying Successful Classification of Amnestic Mild Cognitive Impairment Using Multi-Sensory-Evoked Potentials
利用病毒RNA基因组中的功能区域作为可药物作用的靶点	Luo, D.	PDF	N/A	Exploiting functional regions in the viral RNA genome as druggable entities
利用病毒RNA基因组中的功能区域作为可药物作用的靶点	Luo, D.	PDF	N/A	Exploiting functional regions in the viral RNA genome as druggable entities
在隐球菌中失去RNA干扰后的独特进化轨迹	Huang, J.	PDF	N/A	Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans
OMG数据集：一个用于混合模态基因组语言建模的开源元基因组语料库	Cornman, A.	PDF	N/A	The OMG dataset: An Open MetaGenomic corpus for mixed-modality genomic language modeling
光微生境中的互利共生关系推动了拟态蝴蝶群落中的感觉趋同	Wainwright, J. B.	PDF	N/A	Mutualisms within light microhabitats drive sensory convergence in a mimetic butterfly community
动作意识的神经营机制	Jin, D. S.	PDF	N/A	Neural mechanisms of awareness of action
一个模块化的免疫反应模型作为计算平台，用于研究感染性疾病的发病机制	Miroshnichenko, M.	PDF	N/A	A modular model of immune response as a computational platform to investigate a pathogenesis of infection disease
GM2神经节苷脂病中的质膜重塑驱动突触功能障碍	Nicholson, A. S.	PDF	N/A	Plasma Membrane Remodelling in GM2 Gangliosidoses Drives Synaptic Dysfunction
DeepPWM-BindingNet：结合序列和PWM特征，释放结合预测能力	Ali, S.	PDF	N/A	DeepPWM-BindingNet: Unleashing Binding Predictionwith Combined Sequence and PWM Features
DNA甲基化保护癌细胞免于衰老。	Chen, X.	PDF	N/A	DNA methylation protects cancer cells against senescence
甲醇趋化受体MtpA和鞭毛蛋白FliC依赖的甲醇趋化性决定了PPFM在叶际中的时空定殖	Katayama, S.	PDF	N/A	Methanol chemoreceptor MtpA- and flagellin protein FliC-dependent methylotaxis determines the spaciotemporal colonization of PPFM in the phyllosphere
基因内适应性景观上上位性的变异与可预测性。	Baheti, S.	PDF	N/A	Variations and predictability of epistasis on an intragenic fitness landscape.
使用脂质锚定控制影响外源货物蛋白与细胞外囊泡结合的物理和生化参数，实现高载量和有效的细胞内递送	Marquant, A.	PDF	N/A	Control of Physical and Biochemical Parameters Influencing Exogeneous Cargo Protein association to Extracellular Vesicle using Lipid Anchors Enables High Loading and Effective Intracellular Delivery
实体瘤局部给药后肿瘤-CAR T细胞相互作用的时空动力学	Owens, K.	PDF	N/A	Spatiotemporal dynamics of tumor-CAR T-cell interaction following local administration in solid cancers
棉子糖诱导自噬以促进植物生长	Magen, S.	PDF	N/A	Raffinose induces autophagy to promote plant growth
SMARTER数据库：一种用于整合绵羊和山羊品种SNP阵列数据集的工具	Cozzi, P.	PDF	N/A	SMARTER-database: a tool to integrate SNP arraydatasets for sheep and goat breeds
牙龈卟啉单胞菌外膜囊泡改变了胚胎小鼠大脑中的神经元结构和Tau磷酸化	Bradley, A.	PDF	N/A	Porphyromonas gingivalis outer membrane vesicles alter neuronal architecture and Tau phosphorylation in the embryonic mouse brain
蝾螈的表观遗传时钟为揭示极少衰老现象的本质提供了洞见。	Haluza, Y.	PDF	N/A	Axolotl epigenetic clocks offer insights into the nature of negligible senescence
小脑如何协调运动输出？过去的教训	Gilbert, M.	PDF	N/A	How does the cerebellum coordinate motor outputs? Lessons from the past
在注意力短暂调节过程中，跨感觉模式的共享皮层下觉醒系统	Khalaf, A.	PDF	N/A	Shared subcortical arousal systems across sensory modalities during transient modulation of attention
拟南芥在昼夜和发育时间尺度上的稳定和动态基因表达模式	Redmond, E. J.	PDF	N/A	Stable and dynamic gene expression patterns over diurnal and developmental timescales in Arabidopsis thaliana
基于SENP2的α-突触核蛋白N端截断在路易体病理传播中的作用	Taguchi, K.	PDF	N/A	SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation
基于深度学习的基因扰动效应预测尚未超越简单的线性方法。	Ahlmann-Eltze, C.	PDF	N/A	Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods
聚焦镓离子束的生物体积电子显微镜依赖于在断面形成辐射抗性富镓层	Yang, Z.	PDF	N/A	Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face
高风险神经精神性拷贝数变异与人类脑细胞中趋同的转录组变化相关	Dugan, G.	PDF	N/A	High-risk neuropsychiatric copy number variants are associated with convergent transcriptomic changes in human brain cells
基于SATAY的化学基因组筛选揭示了抗真菌抗性机制及ATI-2307和壳聚糖敏感性的关键决定因素	Karadzas, M. T.	PDF	N/A	SATAY-Based Chemogenomic Screening uncovers Antifungal Resistance Mechanisms and Key Determinants of ATI-2307 and Chitosan Sensitivity
通过使用具有均一N-连接糖基的抗原，利用HDX-MS实现糖蛋白的表位分析	Ota, T.	PDF	N/A	Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans
持续性的细菌Regiella在鸟樱桃-燕麦蚜虫Rhopalosiphum padi中的转染，增加了宿主的适应性并减少了植物病毒的传播。	Yu, W.	PDF	N/A	A persistent bacterial Regiella transinfection in the bird cherry-oat aphid Rhopalosiphum padi increasing host fitness and decreasing plant virus transmission
两种特异性纤毛细胞骨架系统在驱动Hedgehog应答转录因子运输中的协同作用	Ku, P.-i.	PDF	N/A	Collaborative role of two distinct cilium-specific cytoskeletal systems in driving Hedgehog-responsive transcription factor trafficking
慢性淀粉样β寡聚体注射入海马后神经元活动和神经递质释放同时评估的协议	Herve, V.	PDF	N/A	Protocol for simultaneous evaluation of neuronal activity and neurotransmitter release following chronic amyloid-beta oligomer injections into the hippocampus
CLYBL通过修复丙二酰辅酶A，避免了甲基丙二酰辅酶A变位酶的抑制和维生素B12的流失。	Griffith, C. M.	PDF	N/A	CLYBL averts methylmalonyl-CoA mutase inhibition and loss of vitamin B12 by repairing malyl-CoA
持续注意状态的振荡动力学	Solis-Vivanco, R.	PDF	N/A	Oscillatory dynamics of sustained attention states
一种用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱系统	Bazargan, S.	PDF	N/A	A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets
区间删失对生物高通量筛选中数据准确性和机器学习性能的影响	Doffini, V.	PDF	N/A	Impact of Interval Censoring on Data Accuracy and Machine Learning Performance in Biological High-Throughput Screening
脊髓投射的5-羟色胺能神经元对活跃运动状态的增强作用	Fenstermacher, S.	PDF	N/A	Potentiation of active locomotor state by spinal-projecting serotonergic neurons
利用工程化受体实现合成mRNA的胞外配体响应性翻译调控	Nakanishi, H.	PDF	N/A	Extracellular ligand-responsive translational regulation of synthetic mRNAs using engineered receptors
斑马鱼Pol-Theta和人Pol-Theta，具有同源功能的直系同源物	Thomas, C.	PDF	N/A	Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function
鉴定药物/代谢物转运蛋白1作为NF54xCam3.II恶性疟原虫遗传杂交中奎宁耐药性的标志物。	Kanai, M.	PDF	N/A	Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54xCam3.II P. falciparum genetic cross.
时间变化刺激延长IKK激活促进核重塑和NF-κB动力学的机制转换	Smeal, S. W.	PDF	N/A	Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics
分子与神经回路机制：果蝇性经验依赖的长时记忆	Sun, D.	PDF	N/A	Molecular and Neural Circuit Mechanisms Underlying Sexual Experience-dependent Long-Term Memory in Drosophila.
GoldPolish-目标：定向长读长基因组组装抛光	Zhang, E.	PDF	N/A	GoldPolish-Target: Targeted long-read genome assembly polishing
中缝背核中的血清素能神经元调控视觉注意力	Lehnert, J.	PDF	N/A	Serotonergic neurons in the dorsal raphe regulate visual attention
概率模型提高了从基因系统发育中进行相对年代测定的效果。	Bernabeu, M.	PDF	N/A	Probabilistic modelling improves relative dating from gene phylogenies
隐性致病变异携带者的生殖和认知影响	Fridman, H.	PDF	N/A	Reproductive and cognitive effects in carriers of recessive pathogenic variants
通过结构学习捕捉代理的最佳和次优行为	Moongathottathil James, A.	PDF	N/A	Capturing Optimal and Suboptimal behavior Of Agents Via Structure Learning Of Their Internal Model
模块化表征在训练用于执行依赖上下文任务的神经网络中出现	Johnston, W. J.	PDF	N/A	Modular representations emerge in neural networks trained to perform context-dependent tasks
不规律的光照时间表会导致小鼠的日常节律和基因表达发生改变。	Berbegal-Saez, P.	PDF	N/A	Irregular light schedules induce alterations on daily rhythms and gene expression in mice
邻近蛋白质组学揭示了一个与中心体相关的LRRK2调控网络的共同进化	Eckert, M.	PDF	N/A	Proximity proteomics reveals a co-evolved LRRK2-regulatory network linked to centrosomes
UBE3A的重新激活恢复了印记缺陷的安格曼综合征小鼠模型中的行为和蛋白质组	Milazzo, C.	PDF	N/A	UBE3A reinstatement restores behavior and proteome in an Angelman Syndrome mouse model of Imprinting Defects
预测误差的层次结构塑造了依赖于情境的感官表征的学习	Tsai, M. C.	PDF	N/A	Hierarchy of prediction errors shapes the learning of context-dependent sensory representations
用于在体外模拟大脑皮层发育和顺式调控进化的鼠源类器官平台	Medina-Cano, D.	PDF	N/A	A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro
Lgl在有丝分裂退出时重置Par复合物膜加载，以极化神经干细胞	LaFoya, B.	PDF	N/A	Lgl resets Par complex membrane loading at mitotic exit to polarize neural stem cells
去神经骨骼肌的多模态转录反应涉及胆固醇稳态的改变，影响肌肉大小。	Calvo, C.	PDF	N/A	The multimodal transcriptional response of denervated skeletal muscle involves alterations in cholesterol homeostasis impacting muscle size
核孔蛋白Nup153将剪接机器锚定在核孔上，以实现高效的mRNA加工。	De Castro, I.	PDF	N/A	Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing
细胞导航过程中的机械中心体断裂	Schmitt, M. T.	PDF	N/A	Mechanical Centrosome Fracturing during Cell Navigation
快速无标记活体成像揭示了流体动力学和CD44-HA相互作用在癌细胞滞留于内皮单层中的关键作用	Follain, G.	PDF	N/A	Fast label-free live imaging reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers
TET2参与葡萄糖异生并影响2型糖尿病的病理过程。	Zhang, X.	PDF	N/A	TET2 contributes to gluconeogenesis and pathology of type 2 diabetes
肝窦内皮细胞和层粘连蛋白在慢性肝病中决定胆管细胞的命运	Manco, R.	PDF	N/A	Liver Sinusoidal Endothelial Cells and Laminin dictate cholangiocytes fate in chronic liver disease
肌动蛋白-肌球蛋白收缩力是人类多能干细胞诱导中胚层形成的有力抑制因素	Fort, L.	PDF	N/A	Actomyosin Contractility is a Potent Suppressor of Mesoderm Induction by Human Pluripotent Stem Cells
动粒-中心体反馈连接CENP-E和Aurora激酶控制染色体排列	Vukusic, K.	PDF	N/A	Kinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression
去泛素化酶Otub2调节胰腺β细胞功能和存活	Oshry, M.	PDF	N/A	The Deubiquitinating Enzyme Otub2 Modulates Pancreatic Beta-Cells Function and Survival
肌联蛋白依赖的生物力学反馈使昆虫的肌节适应其特殊的肌肉功能	Loreau, V.	PDF	N/A	Titin-dependent biomechanical feedback tailors sarcomeres to specialised muscle functions in insects
在海鞘Ciona中，特异性于被囊动物的蛋白质Epi-1对于赋予幼虫被囊亲水性是必不可少的。	Kuroiwa, K.	PDF	N/A	Tunicate-specific protein Epi-1 is essential for conferring hydrophilicity to the larval tunic in the ascidian Ciona
极体在蜘蛛前后轴形成过程中起到地标作用	Wang, R.	PDF	N/A	Polar bodies serve as a landmark for anteroposterior axis formation in spiders
分支肌动蛋白聚合驱动侵入性突起的形成，以促进骨骼肌再生过程中肌纤维母细胞的融合。	Lu, Y.	PDF	N/A	Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration
早期合子工程促进靶向性大型转基因整合及全转基因动物的直接生产	Gupta, K.	PDF	N/A	Early zygotic engineering promotes targeted large transgene integration and direct production of fully transgenic animals
母体高脂高蔗糖饮食引起的过度肥胖与妊娠晚期胎盘缺氧及胎盘免疫稳态紊乱有关。	Bellissimo, C. J.	PDF	N/A	Maternal high-fat, high-sucrose diet-induced excess adiposity is linked to placental hypoxia and disruption of fetoplacental immune homeostasis in late gestation
RO8191是一种用于在小鼠中启动胚胎植入的新化合物。	Shu, J.	PDF	N/A	RO8191, a new compound for initiating embryoimplantation in mice
胞质增强型基于暗Epac的FRET传感器用于通过FLIM在活细胞中检测细胞内cAMP	Zanetti, G.	PDF	N/A	Cytosolic Enhanced Dark Epac-Based FRET Sensors for Intracellular cAMP detection in live cells via FLIM
SC-MAMBA2：利用状态空间模型实现高效单细胞超长转录组建模	Zhao, Y.	PDF	N/A	SC-MAMBA2: Leveraging State-Space Models for Efficient Single-Cell Ultra-Long Transcriptome Modeling
菊芋提取物调节脂肪酸生物合成中关键酶的基因表达	Bunch, H.	PDF	N/A	Jerusalem artichoke extracts regulate the gene expression of key enzymes involved in fatty acid biosynthesis
低表达的NOTCH1改变了左心发育不良综合征中心肌细胞的细胞结构	Lewis, J.	PDF	N/A	Hypomorphic NOTCH1 Expression Alters Cardiomyocyte Cellular Architecture in Hypoplastic Left Heart Syndrome
钙稳态调节剂2在线粒体中构成一个ATP调控孔	GUO, Q.	PDF	N/A	Calcium Homeostasis Modulator 2 Constitutes an ATP-regulation Pore in Mitochondria
S1PR1调节淋巴管瓣膜发育并防止非肠炎依赖的淋巴样器官形成	Geng, X.	PDF	N/A	S1PR1 Regulates Lymphatic Valve Development And Prevents Ileitis-Independent Tertiary Lymphoid Organ Formation
在拟南芥中，PRESSED FLOWER 通过下游作用于 ASYMMETRIC LEAVES 2 来影响萼片的扁平度。	Liu, R.	PDF	N/A	PRESSED FLOWER works downstream of ASYMMETRIC LEAVES 2 to affect sepal flatness in Arabidopsis
量化生化途径中的癌症药物靶向性	Hagler, S.	PDF	N/A	Quantifying Cancer Drug Targetability across Biochemical Pathways
细菌中脉冲基础基因表达作为适应性决定因素	Jain, K.	PDF	N/A	Pulsatile basal gene expression as a fitness determinant in bacteria
可解释人工智能在MRI分析中的应用：将模型预测与老化大脑的神经影像特征相关联	Hofmann, S. M.	PDF	N/A	The utility of explainable A.I. for MRI analysis: Relating model predictions to neuroimaging features of the aging brain
对具有广谱抗病毒能力的木薯（Manihot esculenta）品系COL40进行单倍体型解析组装，揭示了位于12号染色体上含有大量重复元件的区域，这些病毒是导致木薯褐条病的原因。	Thoben, C.	PDF	N/A	The haplotype-resolved assembly of COL40 a cassava (Manihot esculenta) line with broad-spectrum resistance against viruses causing Cassava brown streak disease unveils a region of highly repeated elements on chromosome 12
使用张量分解的AI驱动计算方法可以在整合多个Hi-C数据集时发现共同的优化bin大小。	Taguchi, Y.-h.	PDF	N/A	Novel AI-powered computational method using tensor decomposition can discover the common optimal bin sizes when integrating multiple Hi-C datasets
基于mRNA的RSV preF疫苗在临床前研究中的疗效和安全性	bai, h.	PDF	N/A	Efficacy and safety of an mRNA-based RSV preF vaccine in preclinical studies
温带森林林下草本植物和禾草类植物对干旱胁迫的形态和生理反应比较	Petek-Petrik, A.	PDF	N/A	Comparison of morphological and physiological response to drought stress among temperate forest understory forbs and graminoids
IQD2招募KLCR1到膜-微管连接处，促进叶表皮铺路细胞的细胞骨架力学响应性	Buhl, J.	PDF	N/A	IQD2 recruits KLCR1 to the membrane-microtubule nexus to promote cytoskeletal mechano-responsiveness in leaf epidermis pavement cells
植物免疫受体广谱识别病原效应蛋白的定向进化	Rim, E. Y.	PDF	N/A	Directed evolution of a plant immune receptor for broad spectrum recognition of pathogen effectors
墨西哥酸橙基因组二倍体组装揭示了广泛的杂合性	Leichty, A.	PDF	N/A	Diploid assembly of the Mexican lime genome reveals extensive heterozygosity
叶片气腔中的不饱和与近似同位素均质性	Collaviti, S. E.	PDF	N/A	Unsaturation and Approximate Isotopic Homogeneity in Leaf Air Spaces
自闭症患者在观察触摸时的动态功能适应：连接强度与对社交触摸的态度和社会反应性有关	Masson, H. L.	PDF	N/A	Dynamic functional adaptations during touch observation in autism: Connectivity strength is linked to attitudes towards social touch and social responsiveness
多种转录因子调控阿氏肠杆菌中易错DNA聚合酶基因的表达	Nguyen, B. H.	PDF	N/A	Multiple transcription factors regulate the expression of genes for error prone DNA polymerases in Acinetobacter baumannii
群体感应和DNA甲基化在临床伯克霍尔德菌的相变中起着积极作用。	Coulon, P. M. L. .	PDF	N/A	Quorum sensing and DNA methylation play active roles in clinical Burkholderia phase variation
双单倍体溪红点鲑（Salvelinus fontinalis）的染色体水平基因组组装	Lecomte, L.	PDF	N/A	Chromosome-level genome assembly of a doubled haploid brook trout (Salvelinus fontinalis)
一种用于缓解晕车的可穿戴正念脑机接口	Zhu, J.	PDF	N/A	A Wearable Mindfulness Brain-Computer Interface for Alleviating Car Sickness
针对嗅觉受体可通过肌动蛋白细胞骨架解聚减轻高残余血小板反应性和动脉血栓形成	Aggarwal, A.	PDF	N/A	Targeting an Olfactory Receptor Mitigates High Residual Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Depolymerization
特定种子特异性过表达改良的小麦Or基因可提高水稻和小麦籽粒中的β-胡萝卜素含量。	Sirohi, P.	PDF	N/A	Seed specific overexpression of a modified wheat Or gene leads to enhanced β-carotene in rice and wheat grains
数据猎人：连接生物信息学教育和微生物组研究	Fumagalli, S.	PDF	N/A	Data Hunters: bridging bioinformatics education and microbiome research
通过完全自主的HABITS系统实现新颖且优化的鼠标行为：家庭笼辅助行为创新与测试系统	Yu, B.	PDF	N/A	Novel and optimized mouse behavior enabled by fully autonomous HABITS: Home-cage Assisted Behavioral Innovation and Testing System
一个模仿大肠杆菌膜生物物理特性的极简模型脂质系统	Tormena, N.	PDF	N/A	A minimalist model lipid system mimicking the biophysical properties of Escherichia coli membrane
R405W desmin敲入小鼠的综合数据显示，肌纤维病初期阶段线粒体功能、蛋白质质量控制和肌纤维结构的改变。	Batonnet-Pichon, S.	PDF	N/A	Integrated data from R405W desmin knock-in mice highlight alterations of mitochondrial function, protein quality control, and myofibrillar structure in the initial stages of myofibrillar myopathy
宿主树木叶片对昆虫病原体多态性的影响	Freedman, A. S.	PDF	N/A	Effects of Host-Tree Foliage on Polymorphism in an Insect Pathogen
宿主树木叶片对昆虫病原体多态性的影响	Freedman, A. S.	PDF	N/A	Effects of Host-Tree Foliage on Polymorphism in an Insect Pathogen
流体流动影响血管炎症纤维化模型中的内皮细胞-单核细胞相互作用	Linares, I.	PDF	N/A	Fluid Flow Impacts Endothelial-Monocyte Interactions in a Model of Vascular Inflammatory Fibrosis
STIX：基于长读长测序的群体规模结构变异精准注释	Zheng, X.	PDF	N/A	STIX: Long-reads based Accurate Structural Variation Annotation at Population Scale
以患者为中心的知识图谱方法，用于优先筛选突变体以进行选择性抗癌靶向治疗	Gorostiola Gonzalez, M.	PDF	N/A	A patient-centric knowledge graph approach to prioritize mutants for selective anti-cancer targeting
负责胸腺功能的基本相互作用解释了复杂的髓质形状	Muramatsu, D.	PDF	N/A	Basic interactions responsible for thymus function explain convoluted medulla shape
从遗传学定义的小鼠肝母细胞瘤中高效衍生出永生化、同基因细胞系	Wang, H.	PDF	N/A	Efficient Derivation of Immortalized, Isogenic Cell Lines from Genetically Defined Murine Hepatoblastomas
早期青少年期第二代抗精神病药物暴露对体重、热量摄入及代谢相关基因表达的长期影响	Soto, P.	PDF	N/A	Long-Term Effects of Early Adolescent Second-Generation Antipsychotic Exposure on Body Weight, Caloric Intake, and Metabolism-Associated Gene Expression
吞噬作用通过PGE2的形成和EP4信号在M1型和M2型巨噬细胞中受到LPS的不同调控。	Kirchhoff, R.	PDF	N/A	Phagocytosis is differentially regulated by LPS in M1- and M2-like macrophages via PGE2 formation and EP4 signaling
印度东部喜马拉雅季节性热带森林中的叶、花和果实物候模式及其与环境的关系	Datta, A.	PDF	N/A	Patterns of leaf, flower and fruit phenology and environmental relationships in a seasonal tropical forest in the Indian Eastern Himalaya
药用植物对南方根结线虫（Meloidogyne javanica）的植物化学分析和杀线虫活性研究	Maher, S.	PDF	N/A	Phytochemical Analysis and Nematicidal Activity of Medicinal Plants Against Meloidogyne javanica
配体结合对人类内皮细胞中VEGFR1、VEGFR2和NRP1定位的影响	Sarabipour, S.	PDF	N/A	Impact of ligand binding on VEGFR1, VEGFR2, and NRP1 localization in human endothelial cells
成年雄性大鼠扣带区（下边缘区和前扣带区，背侧部分）与间脑（间脑）之间的双向连接的地形组织	Negishi, K.	PDF	N/A	Topographic organization of bidirectional connections between the cingulate region (infralimbic area and anterior cingulate area, dorsal part) and the interbrain (diencephalon) of the adult male rat
环境无关物体识别的硬连线视觉滤波器	Kang, M.	PDF	N/A	Hard-wired visual filters for environment-agnostic object recognition
生理因素对静息态和任务态功能连接影响的调查	Askarinejad, S. E.	PDF	N/A	Investigation of the effect of physiological factors on resting-state and task-based functional connectivity
淀粉样β病理加速了5xFAD小鼠视觉通路的改变	McCool, S.	PDF	N/A	Amyloid Beta Pathology Accelerates Alterations in the Visual Pathway of the 5xFAD Mouse
复杂运动轨迹由蝗虫中多个运动敏感的下行中间神经元的总体活动所形成的人口编码来表示。	Zhang, S.	PDF	N/A	Complex motion trajectories are represented by a population code from the ensemble activity of multiple motion-sensitive descending interneurons in locusts
使用鼠尾草酸治疗可减轻IL-33激活后促炎性肥大细胞介质的分泌	Crozier, R. W. E.	PDF	N/A	Treatment with carnosic acid attenuates the secretion of pro-inflammatory mast cell mediators following IL-33 activation
在赫拉克勒斯蚁中，节俭的超个体表型作为一种可塑性反应，出现在极端环境中。	Plante, E.	PDF	N/A	Thrifty superorganism phenotypes emerge as a plastic response to extreme environments in the Hercules ant
珊瑚礁修复的人口基因组学——密克罗尼西亚鹿角珊瑚的案例研究	Rios, D.	PDF	N/A	Population genomics for coral reef restoration - a case study of staghorn corals in Micronesia
加拉帕戈斯群岛Scalesia适应性辐射中的基因组稳定性：尽管存在杂交和生态位转变，转座元件的积累依然一致	Cerca, J.	PDF	N/A	Genomic stability in the Galapagos Scalesia adaptive radiation: Consistent transposable element accumulation despite hybridization and ecological niche shifts
在果蝇中，心脏性能的衰老自然变化揭示了PAR域bZIP转录因子Pdp1/dHLF在心脏衰老中的核心功能	Audouin, K.	PDF	N/A	Natural variations of aging of cardiac performance in Drosophila identifies a central function for the PAR domain bZIP transcription factor Pdp1/dHLF in cardiac senescence
巨大的染色体外元素“Inocle”可能潜在地扩展了人类口腔微生物群的适应能力	Kiguchi, Y.	PDF	N/A	Giant extrachromosomal element "Inocle" potentially expands the adaptive capacity of the human oral microbiome
GeTMoR：同时进行基因组、转录组和形态学的稀有单细胞分析	Prabakar, R. K.	PDF	N/A	GeTMoR: Simultaneous genomic, transcriptomic, andmorphological profiling of rare single cells
在小鼠中对可口糖的暴饮暴食进行情境增强	Matsui, H.	PDF	N/A	Contextual enhancement on binge-like overconsumption of palatable sugar in mice
迭代牺牲三维打印与聚合物铸造技术用于制造复杂血管移植物及多腔室生物人工器官	Brassard, J. A.	PDF	N/A	Iterative sacrificial 3D printing and polymer casting to create complex vascular grafts and multi-compartment bioartificial organs
电阻抗光谱作为一种检测前列腺癌细胞上皮间质转化的工具	Crowell, L. L.	PDF	N/A	Electrical Impedance Spectroscopy as a Tool to Detect the Epithelial to Mesenchymal Transition in Prostate Cancer Cells
一种新型工程化U7小核RNA支架在体外和体内显著增加了ADAR介导的可编程RNA碱基编辑	Byrne, S. M.	PDF	N/A	A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases in vitro and in vivo ADAR-Mediated Programmable RNA Base Editing
一种新型工程化U7小核RNA支架在体外和体内显著增强了ADAR介导的可编程RNA碱基编辑	Byrne, S. M.	PDF	N/A	A Novel Engineered U7 Small Nuclear RNA Scaffold Greatly Increases in vitro and in vivo ADAR-Mediated Programmable RNA Base Editing
PlasmidGPT：一个用于质粒设计和注释的生成框架	SHAO, B.	PDF	N/A	PlasmidGPT: a generative framework for plasmid design and annotation
公民科学家在远足期间未检测到的现象，可以建模为天气、季节、清单长度和个人偏好的函数。	Jacobusse, G. W.	PDF	N/A	Non-detection during excursions by citizen scientists modeled as a function of weather, season, list length, and individual preferences
解锁低质量总RNA-seq数据的潜力：一种逐步映射方法以改进定量分析	Lee, J.	PDF	N/A	Unlocking the Potential of Low Quality Total RNA-seq Data: A Stepwise Mapping Approach for Improved Quantitative Analyses
Eps15 EH结构域与内在无序蛋白质之间的竞争性相互作用形成了一个复杂的相互作用网络。	Papagiannoula, A.	PDF	N/A	Competitive interactions between Eps15 EH domains and intrinsically disordered proteins generate a complex interaction network
弹簧加载的DNA折纸阵列作为模块化纳米机器人的能量供应硬件	Pfeiffer, M.	PDF	N/A	Spring-loaded DNA origami arrays as energy-supplied hardware for modular nanorobots
非整倍体上位性图谱揭示了与癌症中多余染色体相关的代谢脆弱性	Magesh, R. Y.	PDF	N/A	An aneuploidy epistasis map reveals metabolic vulnerabilities associated with supernumerary chromosomes in cancer
基于深度学习的母体心电图推断子宫收缩	Tanaka, S.	PDF	N/A	Deep Learning-Based Inference of Uterine Contractions from Maternal ECG
BMP信号调节控制原条的形成	Simon, G.	PDF	N/A	BMP signaling modulations control primitive streak patterning
鸣禽红眉金丝雀（Neochmia temporalis temporalis）中非典型精子形态的独立进化	Rowe, M.	PDF	N/A	Independent evolution of atypical sperm morphology in a passerine bird, the red-browed finch (Neochmia temporalis temporalis)
在平均任务中，观察结果的不精确计数预测了首因效应和近因效应	Prat-Carrabin, A.	PDF	N/A	Imprecise counting of observations in averaging tasks predicts primacy and recency effects
探索无偿献血者中红细胞参数与血小板指数之间的关联	De, R.	PDF	N/A	Exploring the link between extended red blood cell parameters and platelet indices in voluntary blood donors
层粘连蛋白调控核力学与形态，以控制胶质母细胞瘤细胞的增殖、迁移和侵袭。	Wang, X.	PDF	N/A	Lamins regulate nuclear mechanics and shape to control glioblastoma cell proliferation, migration and invasion
多模态大语言模型实现药物机制和性质的全方位预测	Liang, Y.	PDF	N/A	Multi-Modal Large Language Model Enables All-Purpose Prediction of Drug Mechanisms and Properties
首次完成昆虫眼睛的三维重建与形态功能图谱绘制	Makarova, A. A.	PDF	N/A	The first complete 3D reconstruction and morphofunctional mapping of an insect eye
电磁刺激微丝化水凝胶用于引导神经元形态发生	Jensen, B. N.	PDF	N/A	Electromagnetic Stimulated Microfillamented Hydrogels for Guided Neuronal Morphogenesis
通过将EM算法应用于改进的广义线性模型，将生物学变异与噪声分离	Lee, T.-W.	PDF	N/A	Separating biological variance from noise by applying EM algorithm to modified General Linear Model
利用bond-boost超动力学方法研究蛋白质路径的加速分子动力学研究	Park, S. W.	PDF	N/A	An accelerated molecular dynamics study for investigating protein pathways using the bond-boost hyperdynamics method
巨核细胞构建了一个细胞外基质笼，控制其成熟和锚定于血管壁龛。	Masson, C.	PDF	N/A	Megakaryocytes build a cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
维持神经元中TDP-43的表达需要轴突溶酶体的运输	Ryan, V. H.	PDF	N/A	Maintenance of neuronal TDP-43 expression requires axonal lysosome transport
调节秀丽隐杆线虫进入持久化状态决策的神经元活动	Prakash, S. J.	PDF	N/A	Neuronal activity regulating the dauer entry decision in Caenorhabditis elegans
在实时fMRI神经反馈中引入触觉反馈：一种调节初级运动皮层活动的新方法	Fleury, M.	PDF	N/A	Introducing Haptic Feedback in Real-Time fMRI Neurofeedback: A Novel Approach to Modulate Primary Motor Cortex Activity
鉴定与中国仓鼠卵巢（CHO）细胞适应性相关的细胞特征，以分泌抗体	Bai, Y.	PDF	N/A	Identification of Cellular Signatures Associated with Chinese Hamster Ovary (CHO) Cell Adaptation for Secretion of Antibodies
UniGEN-DDI：利用统一图嵌入网络计算药物-药物相互作用	Mondal, S.	PDF	N/A	UniGEN-DDI: Computing drug-drug interactions using a unified graph embedding network
人类Toll样受体中的亮氨酸重复结构域中个体差异的重复出现解释了它们的多样性和功能适应性。	Takkouche, A.	PDF	N/A	Divergence of the Individual repeats in the leucine-rich repeat domains of human Toll-like receptors explain their diversity and functional adaptations.
RAPDOR：利用Jensen-Shannon距离进行复杂蛋白质组学数据集的计算分析	Hemm, L.	PDF	N/A	RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets
武士：使用可重复且集成的生物信息学管道对拷贝数变异进行浅层分析	Potente, S.	PDF	N/A	SAMURAI: Shallow Analysis of Copy nuMber alterations Using a Reproducible And Integrated bioinformatics pipeline
捕捉哺乳动物细胞的层次分类蛋白质相互作用模块	Dai, S.	PDF	N/A	Capturing the Hierarchically Assorted Protein-protein Interaction Modules of Mammalian Cell
锌离子介导的胱天蛋白酶-3非竞争性抑制的计算分析	Tian, X. E.	PDF	N/A	Computational Analysis of Zn2+ Mediated Non-Competitive Inhibition to Caspase-3
GPCR结构域与功能的关系：受体螺旋束和C端对GRK特异性功能和β-arrestin介导的调控有不同的影响	Matthees, E. S.	PDF	N/A	Relating GPCR domains with functionality: receptor helix-bundle and C-terminus differentially influence GRK-specific functions and β-arrestin-mediated regulation
基准测试用于后扰动RNAseq预测的基础细胞模型	Csendes, G.	PDF	N/A	Benchmarking a foundational cell model for post-perturbation RNAseq prediction
溶质载体超家族互作网络	Frommelt, F.	PDF	N/A	The solute carrier superfamily interactome
VPS35(D620N)敲入小鼠中出现的谷氨酸和多巴胺功能障碍及LRRK2抑制剂的快速逆转	Kamesh, A.	PDF	N/A	Emergent glutamate & dopamine dysfunction in VPS35(D620N) knock-in mice and rapid reversal by LRRK2 inhibition
心理努力和反事实情境对语言理解的影响：老年人ERP证据	Salas-Herrera, J. L.	PDF	N/A	Mental Effort and Counterfactuals Modulate Language Understanding: ERP Evidence in Older Adults
一种无需使用仿真体即可实现PET图像空间分辨率校正的新方法	Carbonell, F.	PDF	N/A	A novel method for harmonization of PET image spatial resolution without phantoms
将显微镜与扩散磁共振成像通过退化的生物物理模型相连接：贝叶斯变化估计（BENCH）框架的应用	Kor, D. Z. L.	PDF	N/A	Linking microscopy to diffusion MRI with degenerate biophysical models: an application of the Bayesian EstimatioN of CHange (BENCH) framework
tau病变的分类揭示了原丝核心残基的作用。	Vaquer-Alicea, J.	PDF	N/A	Functional classification of tauopathy strains reveals the role of protofilament core residues.
奇怪的异常反应反映了小鼠初级视觉皮层中复杂且依赖于情境的预期	Knudstrup, S. G.	PDF	N/A	Oddball evoked deviant responses reflect complex context dependent expectations in mouse V1
CXXC指蛋白1与FOXP3相互作用，以稳定调节性T细胞的稳态和抑制功能	Meng, X.	PDF	N/A	CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells
改变游戏规则的突变	Edhan, O.	PDF	N/A	Game Changing Mutation
甲基组揭示了两种植物物种群体中最近的进化变化	Korfmann, K.	PDF	N/A	Methylomes reveal recent evolutionary changes in populations of two plant species
脂肪组织中瘦素上游增强子表观遗传修饰的性别特异性作用	Mueller, L.	PDF	N/A	Sex-specific role of epigenetic modification of a leptin upstream enhancer in the adipose tissue
基因组关联研究的谱系蒸馏	Christ, R.	PDF	N/A	Clade Distillation for Genome-wide Association Studies
现场采集的蜱虫中存在Powassan病毒缺失和缺陷RNA的证据	Langsjoen, R. M.	PDF	N/A	Evidence for Powassan virus deletions and defective RNA in field collected ticks
通过动态结构学习推断代理的时间变化内部模型	Moongathottathil James, A.	PDF	N/A	Inferring Time-Varying Internal Models of Agents Through Dynamic Structure Learning
同位素标记在MaxQuant中的更新	Ferretti, D.	PDF	N/A	Isobaric labeling update in MaxQuant
在成像质谱数据降维中保留全光谱信息	Moens, R. A. R.	PDF	N/A	Preserving Full Spectrum Information in ImagingMass Spectrometry Data Reduction
BindCraft：功能性蛋白质结合剂的一步设计	Pacesa, M.	PDF	N/A	BindCraft: one-shot design of functional protein binders
瞬时蛋白质结构指导膜超复合物中电子传递的表面扩散路径	Chan, C. K.	PDF	N/A	Transient protein structure guides surface diffusion pathways for electron transport in membrane supercomplexes
在唐氏综合症B细胞急性淋巴母细胞白血病中，可以通过使用Venetoclax靶向代谢脆弱性。	Jones, D.	PDF	N/A	Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax
脑转移中三级淋巴结构的鉴定与特征分析	Mughal, S. S.	PDF	N/A	Identification and characterization of tertiary lymphoid structures in brain metastases
使用性别特异性的心脏模拟器实时预测药物引起的致心律失常风险	Dominguez-Gomez, P.	PDF	N/A	Real-time prediction of drug-induced proarrhythmic risk with sex-specific cardiac emulators
草酸钙结石形成者的酸排泄受损	Silva, P. H. I.	PDF	N/A	Acid excretion is impaired in calcium oxalate stone formers
陆地植物免疫稳态模块的保守性	Dou, R.	PDF	N/A	Conservation of an immune homeostasis module in land plants
小型化实验室设备作为在基础设施有限的西非国家实施保护遗传学工具和教育的解决方案：以几内亚比绍非法野生动物贸易研究为例	da Silva, M. J. F.	PDF	N/A	Miniaturised laboratorial equipment as a solution to implement conservation genetics tools and education in West African countries with limited infrastructures: an application to the study of illegal wildlife trade in Guinea-Bissau
9.4 T下人脑中代谢物和大分子的定量二维J分辨代谢物循环半LASER光谱学	Murali-Manohar, S.	PDF	N/A	Quantitative 2D J-resolved metabolite-cycled semiLASER spectroscopy of metabolites and macromolecules in the human brain at 9.4 T
基于生物学的芯片上脑模型识别出在高度兴奋的神经网络中选择性的地形重组	Poinsot, M.	PDF	N/A	Biologically grounded brain-on-chip model identifies selective topographic reorganization within hyperexcitable neural networks
多巴胺活动在条件性味觉厌恶范式中编码同一刺激的情感变化	Loh, M.	PDF	N/A	Dopamine activity encodes the changing valence of the same stimulus in conditioned taste aversion paradigms
亲社会行为的可分离后效：努力对他人的代价高，但对自己有价值	Zheng, Y.	PDF	N/A	Dissociable after-effects of prosocial acts: Effort is costly for others but valued for self
独特的表达谱揭示了三叉神经系统中胶质细胞的参与，这与创伤后头痛有关。	Nagarajan, G.	PDF	N/A	Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache
传粉者是否在塑造花蜜中必需氨基酸方面发挥作用？	Parkinson, R. H.	PDF	N/A	Do pollinators play a role in shaping the essential amino acids found in nectar?
检测金黄色葡萄球菌核心基因组中推动抗生素抗性的正向选择	Rimmer, C. O.	PDF	N/A	Detection of positive selection driving antimicrobial resistance in the core genome of Staphylococcus epidermidis
具备开发人类基因组标准E701的经验	Vasiliadis, I.	PDF	N/A	Experience in developing the human genome standard E701
scGNN+：将ChatGPT适配于无缝教程与代码优化	Jiang, Y.	PDF	N/A	scGNN+: Adapting ChatGPT for Seamless Tutorial and Code Optimization
小鼠前列腺腺体中的核苷酸酶和嘌呤能受体	Yu, J.	PDF	N/A	Ectonucleotidases and Purinergic Receptors in Mouse Prostate Gland
CalTrig：一种基于图形用户界面的机器学习方法，用于解码自由活动啮齿动物中的神经元钙瞬变	Lange, M. A.	PDF	N/A	CalTrig: A GUI-Based Machine Learning Approach for Decoding Neuronal Calcium Transients in Freely Moving Rodents
通过罗望子果实乙醇提取物改善氟化钠处理的大鼠氧化应激	Usman, L. A.	PDF	N/A	Amelioration of Oxidative Stress in Sodium Fluoride-administered Wistar Rats by Tamarindus indica Fruit Pulp Ethanolic Extract
利用分子模拟和机器学习辅助的CDR移植技术设计靶向SARS-CoV-2刺突糖蛋白的纳米抗体	Ferraz, M. V. F.	PDF	N/A	Design of nanobody targeting SARS-CoV-2 spike glycoprotein using CDR-grafting assisted by molecular simulation and machine learning
多样化的、微型化的和祖先的部件用于哺乳动物基因组工程和分子记录	McDiarmid, T. A.	PDF	N/A	Diversified, miniaturized and ancestral parts for mammalian genome engineering and molecular recording
Cxcl10在小鼠SARS-CoV-2感染期间对生存至关重要	Majumdar, S.	PDF	N/A	Cxcl10 is required for survival during SARS-CoV-2 infection in mice
一个独特的细菌家族再次出击！	Shukla, G.	PDF	N/A	A unique bacterial family strikes again!
隐孢子虫微粒体中替代性电子传递链的功能	Deng, S.	PDF	N/A	Function of the alternative electron transport chain in the Cryptosporidium parvum mitosome
MutRS群体感应系统控制人类病原体变异链球菌中的细菌素变菌素生产。	Wyllie, R. M.	PDF	N/A	The MutRS quorum sensing system controls lantibiotic mutacin production in the human pathogen Streptococcus mutans
克鲁兹锥虫细胞图谱；理解寄生虫种群异质性和分化的单细胞资源。	Laidlaw, R.	PDF	N/A	The Trypanosoma cruzi cell atlas; a single-cell resource for understanding parasite population heterogeneity and differentiation.
临床收集的细菌性阴道病诊断样本中阴道微生物群的特征分析	Brochu, H. N.	PDF	N/A	Characterization of vaginal microbiomes in clinician-collected bacterial vaginosis diagnosed samples
从rocaglates/aglains库筛选中体外发现手足口病的治疗先导	Oo, A.	PDF	N/A	In vitro discovery of a therapeutic lead for HFMD from a library screen of rocaglates/aglains
PfPPM2信号传导调控人类疟原虫恶性疟原虫的无性分裂和有性转换	Rawat, A.	PDF	N/A	PfPPM2 signalling regulates asexual division and sexual conversion of human malaria parasite Plasmodium falciparum
B组链球菌通过裂解内皮细胞感染大脑，在斑马鱼脑膜炎模型中	Ravishankar, S.	PDF	N/A	Group B streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model
替考拉宁在体外可减轻RNA病毒感染	Espano, E.	PDF	N/A	Teicoplanin attenuates RNA virus infection in vitro
依赖于Rho的终止和RNase E介导的切割：多顺反子mRNA 3'端加工的双重途径	Jeon, H. J.	PDF	N/A	Rho-dependent termination and RNase E-mediated cleavage: Dual pathways for RNA 3' end processing in polycistronic mRNA
一种新型重组聚羟基丁酸（PHB）生产平台，在丝状蓝藻中避免氮饥饿的同时保持细胞活力	Fink, P.	PDF	N/A	A novel recombinant PHB production platform in filamentous cyanobacteria avoiding nitrogen starvation while preserving cell viability
骨细胞树突中mRNA的转运与翻译	Mazur, C. M.	PDF	N/A	Trafficking and translation of mRNA in osteocyte dendrites
晚年短期饮食限制改善了肠道干细胞功能，并影响了肠道干细胞的DNA甲基化。	Kurup, K.	PDF	N/A	Late-life short-term dietary restriction ameliorates intestinal stem cell function and impacts intestinal stem cell DNA methylation
可扩展制造用于自动化室温X射线蛋白质晶体学的阵列型固定靶装置	Saha, S.	PDF	N/A	Scalable Fabrication of an Array-Type Fixed-Target Device for Automated Room Temperature X-ray Protein Crystallography
长角甲虫利用磷酸钙生物矿物形成结构色	Chang, Y.	PDF	N/A	Longhorn Beetles form Structural Colour Using Calcium Phosphate Biominerals
利用计算机模拟和表征爱泼斯坦-巴尔病毒的LMP1蛋白	Abdul Salam, D. S.	PDF	N/A	In silico modelling and characterization of Epstein Barr virus LMP1 protein
HRS的二维凝聚体驱动扁平网格蛋白笼在内涵体上的组装	Hakala, M.	PDF	N/A	Two-dimensional condensates of HRS drive the assembly of flat clathrin lattices on endosomes
开发高效且选择性的CK1α分子胶降解剂	Geng, Q.	PDF	N/A	Development of potent and selective CK1α Molecular Glue Degraders
计算人类相互作用组	Zhang, J.	PDF	N/A	Computing the Human Interactome
塑造哺乳动物PRPS酶复合体的进化起源与创新	Karki, B.	PDF	N/A	Evolutionary origins and innovations sculpting the mammalian PRPS enzyme complex
一种具有共同参考框架的分子表示系统，用于天然产物途径发现和结构多样性任务。	Babineau, N.	PDF	N/A	A molecular representation system with a common reference frame for natural products pathway discovery and structural diversity tasks.
新世界哺乳动物沙粒病毒刺突复合物抗原糖蛋白构建块的结构与稳定化	Paesen, G. C.	PDF	N/A	Structure and stabilization of the antigenic glycoprotein building blocks of the New World mammarenavirus spike complex
c-di-GMP效应蛋白FleQ通过抑制Azotobacter vinelandii中algD基因的转录来控制海藻酸盐的产生。	BARRIOS-RAFAEL, V. V.	PDF	N/A	The c-di-GMP effector FleQ controls alginate production by repressing transcription of the algD gene in Azotobacter vinelandii
肺炎球菌素B是一种链球菌素B，作为早期感受态级联反应的一部分产生，并促进种内竞争。	Richardson, J. D.	PDF	N/A	The pneumococcal bacteriocin streptococcin B is produced as part of the early competence cascade and promotes intraspecies competition.
来自阴沟肠杆菌的一种岩藻糖结合超凝集素，具有高度的Lewis和ABO血型抗原特异性。	Beshr, G.	PDF	N/A	A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity
多组学分析揭示了BnC07MYB3a在甘蓝型油菜种皮颜色中的作用机制。	Hu, R.	PDF	N/A	Multi-omics analysis reveals the mechanism of BnC07MYB3a is involved in seed coat color in Brassica napus L.
CK1α、FAM83H和FAM83B参与神经丝的捆绑，并在ARSACS的细胞和小鼠模型中被隔离。	Atkinson, C. S.	PDF	N/A	CK1α, FAM83H, and FAM83B contribute to bundling of neurofilaments and are sequestered in cellular and mice models of ARSACS
细胞色素c在人类卵母细胞线粒体代谢中的作用	Surmacki, J. M.	PDF	N/A	The role of cytochrome c in mitochondrial metabolism of human oocytes
使用可解释的机器学习理解TCR T细胞敲除行为	Blennemann, M.	PDF	N/A	Understanding TCR T cell knockout behavior using interpretable machine learning
THEMIS的CABIT2结构域的结构揭示了一种新型蛋白质折叠，其中插入了一个类似SH3的结构域	Beyett, T. S.	PDF	N/A	Structure of the CABIT2 domain of THEMIS reveals a novel protein fold with an inserted SH3-like domain
超分辨率轴向成像用于量化活细胞中的皮牛顿牵引力	Wang, D.-X.	PDF	N/A	Super-Resolution Axial Imaging for Quantifying Piconewton Traction Forces in Live-cells
从头设计与萘二酰亚胺结合的蛋白质，萘二酰亚胺是一种具有可调光物理性质的强效光氧化剂	Mann, S. I.	PDF	N/A	De novo design of proteins that bind naphthalenediimides, powerful photooxidants with tunable photophysical properties
通过信息瓶颈，褶皱的睫状丛在无神经动物中塑造了展开动力学	Brannon, C. M.	PDF	N/A	Creased ciliary flocks shape unfolding dynamics via information bottlenecks in an aneural animal
超声机械基因肿瘤预处理联合SynNotch CAR-T疗法	Yoon, C. W.	PDF	N/A	Tumor Priming by Ultrasound Mechanogenetics for with SynNotch CAR T Therapy
水杨酸、过氧化氢酶2和AtSAP5的精细调节激发植物免疫	Chang, L.	PDF	N/A	Delicate tuning of H2O2 by salicylic acid, catalase 2, and AtSAP5 incites plant immunity
德克萨斯A&M国际大学两个不同干扰水平地点的节肢动物多样性	Siller, E.	PDF	N/A	Arthropod Diversity at Two Sites with Different Disturbance Levels at the Texas A&M International University
植物SCAR/WAVE功能分化的分子基础	Brumm, S.	PDF	N/A	A molecular basis for plant SCAR/WAVE functional divergence
# BioRxiv 2024-09-30 Papers

标题	作者	PDF链接	代码仓库	Title
利用双滴定微点测定法对血清抗体反应进行深度物化表征	Kovacs, A.	PDF	N/A	Deep physico-chemical characterization of the serum antibody response using a dual-titration microspot assay
TMPRSS2对Omicron谱系Spike糖蛋白的激活受到ACE2的Collectrin样域的调控	Aggarwal, A.	PDF	N/A	TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2
端粒通过非端粒TRF2控制人类端粒酶（hTERT）的表达。	Sengupta, A.	PDF	N/A	Telomeres control human telomerase (hTERT) expression through non-telomeric TRF2
测序、Ludwigia叶绿体基因组的从头组装以及在Onagraceae科内的比较分析	Barloy-Hubler, F.	PDF	N/A	Sequencing, de novo assembly of Ludwigia plastomes, and comparative analysis within the Onagraceae family
INSTINCT：通过随机域转换实现空间染色质可及性测序数据的多样本整合	Liu, Y.	PDF	N/A	INSTINCT: Multi-sample integration of spatial chromatin accessibility sequencing data via stochastic domain translation
MTALTCO1：一种由线粒体DNA编码的259个氨基酸长的替代蛋白，挑战了传统线粒体基因组学的理解。	Robitaille, F.	PDF	N/A	MTALTCO1: a 259 amino-acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics
基于视频的生物力学分析捕捉到了不同神经肌肉疾病的疾病特异性运动特征。	Ruth, P.	PDF	N/A	Video-based biomechanical analysis captures disease-specific movement signatures of different neuromuscular diseases
在稻珊瑚（Montipora capitata）中，存在一种进化上保守的Hox-Gbx分节代码	He, S.	PDF	N/A	An evolutionarily conserved Hox-Gbx segmentation code in the rice coral Montipora capitata
慢性使用氟西汀会下调前额叶皮质中小清蛋白中间神经元的线粒体活性。	Jetsonen, E.	PDF	N/A	Chronic treatment with fluoxetine downregulates mitochondrial activity in parvalbumin interneurons of prefrontal cortex
从结构MRI图像生成合成TSPO PET图谱	Ferrante, M.	PDF	N/A	Generation of synthetic TSPO PET maps from structural MRI images
黑质外路易体病的模型中能量代谢改变和昼夜节律紊乱的分子特征。	Lin, L.	PDF	N/A	Molecular signatures of altered energy metabolism and circadian rhythm perturbations in a model of extra-nigral Synucleinopathy.
成骨细胞衍生的红细胞生成素调节应激性红细胞生成过程中的肝脏铁调素	Myneni, V. D.	PDF	N/A	Osteocyte-derived erythroferrone regulates liver hepcidin during stress erythropoiesis
芽殖酵母亚门中朊毒素样杀伤毒素的古老起源与高度多样性	Heneghan, P. G.	PDF	N/A	Ancient origin and high diversity of zymocin-like killer toxins in the budding yeast subphylum
心肌内皮素调节心肌细胞增殖与心脏再生	Sorensen, D. W.	PDF	N/A	Myocardial Endoglin Regulates Cardiomyocyte Proliferation and Cardiac Regeneration
在突变热点驱动的克隆性造血中未发现免疫监视的证据	Walkowiak, B.	PDF	N/A	No evidence of immunosurveillance in mutation-hotspot driven clonal haematopoiesis
UPR诱导的细胞内C5aR1通过调节肿瘤细胞命运，促进对低氧肿瘤微环境的适应。	Suwa, T.	PDF	N/A	UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment by regulating tumour cell fate
人类肺癌恶病质的新型临床前模型	Snoke, D. B.	PDF	N/A	Novel preclinical model of human lung cancer cachexia
长非编码RNA UCA1通过含SMARCA2的SWI/SNF复合物影响人类结直肠癌中的染色质重塑。	Neve, B.	PDF	N/A	Long non-coding RNA UCA1 affects chromatin remodeling via SMARCA2-containing SWI/SNF complex in human colorectal cancer.
打破循环：如何通过靶向CD44v6/MET信号通路破坏结直肠癌细胞的可塑性	Sonnentag, S. J.	PDF	N/A	Breaking the cycle: How targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity
斑马鱼胶质-血管相互作用在脑发育过程中逐渐扩展	Gall, L. G.	PDF	N/A	Zebrafish glial-vascular interactions progressively expand over the course of brain development
父母照顾会改变早期体型和生长在塑造未来生理机能中的作用	Laubach, Z. M.	PDF	N/A	Parental care modifies the role of early-life size and growth in shaping future physiology
细菌运动模式能够平滑地适应空间限制和无序环境。	Zhang, H.	PDF	N/A	Bacterial motility patterns adapt smoothly in response to spatial confinement and disorder
鉴定SLC45A4为编码神经元多胺转运体的疼痛基因。	Middleton, S. J.	PDF	N/A	Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter.
基于将听觉伪词声音映射到多个意义域的声学参数组合：一种机器学习方法	Kumar, G. V.	PDF	N/A	Acoustic parameter combinations underlying mapping of auditory pseudoword sounds to multiple domains of meaning: a machine learning approach
当前人类神经科学研究中的报告实践	Gard, A. M. S.	PDF	N/A	Current Reporting Practices in Human Neuroscience Research
探索儿童非感染性葡萄膜炎中的微小RNA特征：患者样本的荟萃分析与分子谱分析	Wawrzyniak, O.	PDF	N/A	Exploring MicroRNA Signatures in Pediatric Non-infectious Uveitis: Meta-Analysis and Molecular Profiling of Patient Samples
小鼠胚胎植入前单细胞蛋白质组学揭示早期卵裂球中某些蛋白质的显著不对称性	Yuan, Y.	PDF	N/A	Single-cell proteomics of pre-implantation mouse embryos uncovers distinct asymmetry of certain proteins among early blastomeres
代谢重编程调控斑马鱼尾鳍再生过程中的组蛋白乳酸化	Borbinha, J.	PDF	N/A	Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration
GoldPolish-目标：针对长读长基因组组装的靶向抛光	Zhang, E.	PDF	N/A	GoldPolish-Target: Targeted long-read genome assembly polishing
全血转录组分析揭示了运动神经元疾病（MND）的RNA生物标志物特征	Koks, S.	PDF	N/A	Whole blood transcriptome profile identifies motor neurone disease (MND) RNA biomarker signatures
鉴定出利什曼原虫中一种位于基体的新型ε-微管蛋白	Seth, A.	PDF	N/A	Identification of a novel basal body-localized epsilon-tubulin in Leishmania
AFG3L2介导的蛋白水解作用在低氧条件下限制了线粒体生物合成和基因表达。	Chandragiri, S.	PDF	N/A	AFG3L2-mediated proteolysis restricts mitochondrial biogenesis and gene expression in hypoxia
一个MEF2C转录因子网络调控糖尿病肾病中肾小球内皮细胞的增殖	Melo Ferreira, R.	PDF	N/A	A MEF2C transcripton factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease
听觉毛细胞的静纤毛膜力学特性的动态调节通过机械转导复合体的混乱实现	Sam George, S.	PDF	N/A	Dynamic modulation of auditory hair cell stereocilia membrane mechanics by the scrambling mechanotransduction complex
ALG-1，一种微RNA的Argonaute蛋白，促进了秀丽隐杆线虫的阴门诱导过程。	Zhen, S.	PDF	N/A	ALG-1, a microRNA argonaute, promotes vulva induction in C. elegans
从精子在卵母细胞中的运动轨迹推断，透明带和卵周间隙在促进配子融合和多精受精快速阻断中起关键作用。	Dubois, Y.	PDF	N/A	Key roles of the zona pellucida and perivitelline space in promoting gamete fusion and fast block to polyspermy inferred from the choreography of spermatozoa in mice oocytes
p24家族成员TMED9通过快速内质网应激诱导的出口途径，将错误折叠的GPI锚定蛋白从内质网清除到高尔基体。	Ronzier, E.	PDF	N/A	The p24-family member, TMED9, clears misfolded GPI-anchored proteins from theER to the Golgi via the Rapid ER Stress-Induced Export pathway
人神经细胞图谱在发育中人脑组织中的寨卡感染：病毒发病机制、先天免疫和谱系重编程	Stokes, C.	PDF	N/A	The Human Neural Cell Atlas of Zika Infection in developing human brain tissue: viralpathogenesis, innate immunity, and lineage reprogramming
硫化叶菌属中基于社区的DNA修复机制的新组分	Recalde, A.	PDF	N/A	New components of the community based DNA-repair mechanism in Sulfolobales
分化方案依赖性变异性在人诱导多能干细胞衍生的内皮祖细胞功能中的表现	Stern, B.	PDF	N/A	Differentiation Protocol-Dependent Variability in hiPSC-Derived Endothelial Progenitor Functionality
久坐生活方式导致大鼠骨骼肌氧化应激和萎缩	Gungor, I.	PDF	N/A	Sedentary lifestyle induces oxidative stress and atrophy in rat skeletal muscle
大麻表达图谱：一个综合资源，用于大麻（Cannabis sativa L.）基因表达的整合分析	Barbosa-Xavier, K.	PDF	N/A	Cannabis Expression Atlas: a comprehensive resource for integrative analysis of Cannabis sativa L. gene expression
神经任务状态的主动重构	Ritz, H.	PDF	N/A	Active reconfiguration of neural task states
蜜蜂血脑屏障的超微结构组织及其与年龄的比较	Quigley, T.	PDF	N/A	Ultrastructural Organization of the Honeybee Blood-Brain Barrier and Comparison with Age
使用统一流程对多中心大鼠感觉诱发功能磁共振成像数据集进行激活图谱绘制。	Galteau, M. E.	PDF	N/A	Activation mapping in multi-center rat sensory-evoked functional MRI datasets using a unified pipeline.
裸盖菇素可防止小鼠初级听觉皮层对熟悉刺激的习惯化，并在反复刺激后保持对声音的敏感性。	Lane, C. P.	PDF	N/A	Psilocybin prevents habituation to familiar stimuli and preserves sensitivity to sound following repeated stimulation in mouse primary auditory cortex.
针对神经纤毛蛋白-1以增强黑色素瘤免疫治疗：减少肿瘤进展及外周Treg介导的免疫抑制	Khamaru, S.	PDF	N/A	Targeting Neuropilin-1 to Enhance Immunotherapy in Melanoma: Reducing Tumour Progression and Peripheral Treg-Mediated Immunosuppression
颗粒溶素抗菌活性促进结核分枝杆菌进入休眠状态	Schmidiger, S.	PDF	N/A	Granulysin antimicrobial activity promotes dormancy in Mycobacterium tuberculosis
路杀是迁徙性帝王蝶数量下降的关键因素	Momeni-Dehaghi, I.	PDF	N/A	Roadkill is a crucial factor in the population decline of migratory monarch butterflies
河流网络中的多种压力源：对淡水大型无脊椎动物的局部及下游影响	Burgazzi, G.	PDF	N/A	Multiple stressors in river networks: local and downstream effects on freshwater macroinvertebrates
蝴蝶花蜜知识的三重量子飞跃：全面研究革新保护策略	Dunlap, S. C.	PDF	N/A	Three Fold Quantum Leap in Butterfly Nectar Knowledge: A Comprehensive Study Revolutionizing Conservation Strategies
通过原生短暂低氧成像技术观察组织损伤、水肿区域及前哨淋巴结的淋巴动态。	Mendoza, M. I. O.	PDF	N/A	Lymphatic dynamics visualized by native transient hypoxia imaging in areas of tissue damage, edema and in sentinel lymph nodes.
曲霉菌细胞壁完整性激酶MpkA影响改变菌丝材料力学性能的细胞表型	Gray, K.	PDF	N/A	Aspergillus nidulans cell wall integrity kinase, MpkA, impacts cellular phenotypes that alter mycelial-material mechanical properties
预测透析器选择和透析液流速对胆红素清除的影响	Novokhodko, A.	PDF	N/A	Predicting the Impact of Dialyzer Choice and Binder Dialysate Flow Rate on Bilirubin Removal
通过加权TREE-QMC方法，提高了对基因树不完整性、估计误差和系统性同源错误（homology errors）的鲁棒性。	Han, Y.	PDF	N/A	Improved robustness to gene tree incompleteness, estimation errors, and systematic homology errors with weighted TREE-QMC
基于线粒体功能和细胞死亡模式的肝细胞癌患者MPCD指数	Wang, L.-X.	PDF	N/A	MPCD Index for Hepatocellular Carcinoma Patients Based on Mitochondrial Function and Cell Death Patterns
通过透析环境中环糊精实现膜甾醇水平的可逆调节	Alsayyah, C.	PDF	N/A	Reversible tuning of membrane sterol levels by cyclodextrin in a dialysis setting
LC8通过异质性桥接53BP1寡聚体来增强53BP1焦点	Howe, J.	PDF	N/A	LC8 enhances 53BP1 foci through heterogeneous bridging of 53BP1 oligomers
用于单分子显微镜的可重复使用微流控室	Alfehaid, J.	PDF	N/A	Reusable Microfluidic Chambers for Single-Molecule Microscopy
细胞在受限迁移过程中牵引力的测量	Hockenberry, M. A.	PDF	N/A	Measurement of cellular traction forces during confined migration
衰老和瓦螨寄生对蜜蜂血脑屏障的细胞旁通透性和跨细胞通透性的影响	Quigley, T. P.	PDF	N/A	Effect of aging and Varroa parasitism on the paracellular and transcellular permeability of the honeybee blood-brain barrier
同步化的染色质组织作为基于麻醉的植物意识中的强效生物标志物	Chandra, S.	PDF	N/A	Synchronized Chromatin Organization Serves as Potent Biomarker in Anaesthesia-based Plant Consciousness
通过结合免疫荧光和RNA原位杂交技术，在细胞核内同时观察到Pol II和马铃薯纺锤块茎类病毒RNA。	Ma, J.	PDF	N/A	Simultaneous observation of Pol II and potato spindle tuber viroid RNA in the nucleus by combining immunofluorescence and RNA in situ hybridization
番茄中辣椒红素/辣椒玉红素合酶的表达改变了果实类胡萝卜素库，并增强了维生素A原的风味挥发性物质	Fu, J.	PDF	N/A	Expression of Capsanthin/Capsorubin Synthase in Tomato Alters Fruit Carotenoid Pools, and Flavor Volatiles Enhancing Provitamin A
虚拟植物实验室：一个基于Julia的现代化植物建模框架	Morales, A.	PDF	N/A	The Virtual Plant Laboratory: a modern plant modeling framework in Julia
在帕金森病小鼠模型中，恢复多巴胺能神经元中的Fbxo7表达可恢复酪氨酸羟化酶	Laman, H.	PDF	N/A	Restoration of Fbxo7 expression in dopaminergic neurons restores tyrosine hydroxylase in a mouse model of Parkinson's disease
LPS诱导的小鼠类谵妄行为和微胶质激活与双谱脑电图（BSEEG）相关	Nishiguchi, T.	PDF	N/A	LPS-induced delirium-like behavior and microglial activation in mice correlate with bispectral electroencephalography (BSEEG)
当注意力受到伤害：rTMS对时间知觉神经相关性的影响	Conto, F.	PDF	N/A	When Attention Hurts: The Effect Of rTMS On Neural Correlates Of Time Perception
蓝斑核磁共振完整性与结构体积的逆向关联及其对个体注意力不集中的影响	Neal, J.	PDF	N/A	Inversed association of locus coeruleus MRI integrity with structural volume and its impact on individual's inattentiveness
时间压力下目标导向控制与习惯性控制之间的情境依赖性交互作用	Froelich, S.	PDF	N/A	Context-Dependent Interaction Between Goal-Directed and Habitual Control Under Time Pressure
非侵入性大脑刺激前额极皮质可促进在类似觅食的序列选择任务中付出认知努力的意愿	Bogdanov, M.	PDF	N/A	Non-invasive brain stimulation over the Frontopolar Cortex promotes willingness to exert cognitive effort in a foraging-like sequential choice task
全皮层θ振荡的时空模式与自由移动行为相耦合	Sattler, N. J.	PDF	N/A	Cortex-wide spatiotemporal motifs of theta oscillations are coupled to freely moving behavior
年龄和地区特异性代谢物浓度校正的水放松图谱	Simegn, G. L.	PDF	N/A	A Water Relaxation Atlas for Age and Region specific Metabolite Concentration Correction
通过在神经元中删除质子激活的氯离子通道，导致内体过度酸化，从而损害AMPA受体的内吞作用和长时程抑制（LTD）。	Chen, K.	PDF	N/A	Endosomal hyper-acidification via proton-activated chloride channel deletion in neurons impairs AMPA receptor endocytosis and LTD
致幻剂假说：通过依赖回放的可塑性机制来模拟经典致幻剂的幻觉效应	Bredenberg, C.	PDF	N/A	The oneirogen hypothesis: modeling the hallucinatory effects of classical psychedelics in terms of replay-dependent plasticity mechanisms
ACE1不影响5XFAD小鼠大脑中Aβ降解或淀粉样斑块的积累	Jeon, S.	PDF	N/A	ACE1 Does Not Influence Cerebral Aβ Degradation or Amyloid Plaque Accumulation in 5XFAD Mice
内质网应激调节因子IRE1α的激活会损害肺部宿主防御功能。	Sharma, A.	PDF	N/A	Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses
环境机械异质性对T细胞功能的影响	Pandit, J. J.	PDF	N/A	Effect of the Environmental Mechanical Heterogeneity on T Cell Function
损伤诱导的IL-18刺激胸腺NK细胞，限制内源性组织再生	Granadier, D.	PDF	N/A	Damage-induced IL-18 stimulates thymic NK Cells limiting endogenous tissue regeneration
衰老的僵硬交响曲：衰老的骨细胞如何失去它们的弹性节奏	Tilton, M.	PDF	N/A	Stiffening Symphony of Aging: How Senescent Osteocytes Lose Their Elastic Rhythm
PA2G4、MCRS1和SOBP对SIX1+EYA转录活性的直接和间接调控	Jourdeuil, K.	PDF	N/A	Direct and Indirect Regulation of SIX1+EYA Transcriptional Activity by PA2G4, MCRS1, and SOBP
在农业土壤中，线虫拮抗物的多样性及其受根结线虫密度和覆盖作物影响的可调控性	Cazzaniga, S. G.	PDF	N/A	On the diversity of nematode antagonists in an agricultural soil, and their steerability by root-knot nematode density and cover crops
一种用于两栖动物、龟类和鱼类eDNA元条形码的新型简并引物组	Rodgers, T. W.	PDF	N/A	A novel degenerate primer set for eDNA metabarcoding of amphibians, turtles and fish
缺氧威胁珊瑚和海葵的早期生命阶段	Glass, B. H.	PDF	N/A	Hypoxia threatens coral and sea anemone early life stages
在中国，多样化措施减轻了农药对蜜蜂的影响，但未能减轻微塑料的影响，同时并未影响油菜籽产量。	Lin, W.	PDF	N/A	Diversification mitigates pesticide but not microplastic effects on bees without compromising rapeseed yield in China
在近期经历过多倍体化和基因渐渗的植物属中，基因树拓扑空间的地形	Landis, J.	PDF	N/A	The topography of gene tree topology space in a plant genus with a legacy of recent polyploidy and introgression
CAYSS：用于酵母孢子分离自动流式细胞分析的软件包	Raffoux, X.	PDF	N/A	CAYSS: package for automatic Cytometry Analysis of Yeast Spore Segregation
光合共生塑造了巨蛤的基因组结构与基因进化	Li, R.	PDF	N/A	Photosymbiosis Shaped Animal Genome Architecture and Gene Evolution as Revealed in Giant Clams
追踪串联重复序列：一种可定制的识别和跨物种比较的管道	de Lima Adam, C.	PDF	N/A	TRACKing Tandem Repeats: a customizable pipeline for identification and cross-species comparisons
昼行性啮齿动物——白尾黄鼠（Ammospermophilus leucurus）中，昼夜节律的同步化缺失及对周期性厌恶刺激的夜间可塑性有限	Zhang, V.	PDF	N/A	Lack of circadian entrainment and limited nocturnal plasticity in response to a cyclic aversive stimulus in a diurnal rodent, the antelope ground squirrel (Ammospermophilus leucurus)
随着年龄增长，小鼠子宫的生物力学和组成变化	Domingo, M. J. E.	PDF	N/A	Biomechanical and Compositional Changes in the Murine Uterus with Age
电休克疗法和磁休克疗法诱发癫痫的最佳频率	Peterchev, A. V.	PDF	N/A	Optimal Frequency for Seizure Induction with Electroconvulsive Therapy and Magnetic Seizure Therapy
使用混合融合Transformer从CT中精炼心肌分割	Qin, S.	PDF	N/A	Refined Myocardium Segmentation from CT Using a Hybrid-Fusion Transformer
基于模型的强化学习用于超声驱动的自主微型机器人	Medany, M.	PDF	N/A	Model-Based Reinforcement Learning for Ultrasound-Driven Autonomous Microrobots
不同的基因调控网络调控造血干细胞和白血病干细胞	Zhang, B.	PDF	N/A	Distinct gene regulatory networks govern hematopoietic and leukemia stem cells
FragLlama：分子设计的下一个片段预测	Che, X.	PDF	N/A	FragLlama: Next-fragment prediction for molecular design
五物种进化空间循环博弈中存在缺失和非缺失优势网络的长期物种共存	Cliff, D.	PDF	N/A	On Long-Term Species Coexistence in Five-Species Evolutionary Spatial Cyclic Games with Ablated and Non-Ablated Dominance Networks
《你好，你好》：高效预测变构位点的数据驱动方法	Dong, T.	PDF	N/A	Allo-Allo: Data-efficient prediction of allosteric sites
LightMed：一种轻量级且基于FFT的鲁棒模型，用于对抗性弹性的医学图像分割	Pham, V. T.	PDF	N/A	LightMed: A Light-weight and Robust FFT-Based Model for Adversarially Resilient Medical Image Segmentation
利用荧光相关光谱技术对体外裂解液中合成的蛋白质进行实时亲和力测量的方法	Liu, C.	PDF	N/A	Real-time affinity measurements of proteins synthesized in cell-free lysate using fluorescence correlation spectroscopy
单克隆抗体与两亲性聚合物在气-水界面上的竞争吸附	Hingst, E. J.	PDF	N/A	Competitive Adsorption of a Monoclonal Antibody and Amphiphilic Polymers to the Air-Water Interface
RapA 打开 RNA 聚合酶夹，以破坏终止后复合物并防止形成细胞毒性 R 环。	Brewer, J. J.	PDF	N/A	RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation
细胞内细胞器在运输途径中的主动形态动力学	Rautu, S. A.	PDF	N/A	Active morphodynamics of intracellular organelles in the trafficking pathway
冷冻电镜展示了驱动蛋白激活途径的多个步骤	Kendrick, A.	PDF	N/A	Cryo-EM visualizes multiple steps of dynein activation pathway
纳米团簇介导的巨噬细胞炎症反应中FcγR与TLR4之间的信号交叉对话	Lee, S.	PDF	N/A	Nanocluster-Mediated Signaling Crosstalk between FcγR and TLR4 in Macrophage Inflammatory Responses
潜在的TGF-β具有一种域交换的结构。	Jin, M.	PDF	N/A	Latent-TGF-β has a domain swapped architecture
不同的神经内分泌亚型预测治疗诱导的神经内分泌前列腺癌预后，并为个性化治疗提供线索	Hong, Y.-C.	PDF	N/A	Distinct neuroendocrine subtypes predict treatment-induced neuroendocrine prostate cancer prognosis and provide clues for personalized treatment
茎水含量对于在地中海气候下热浪期间支持果树功能至关重要。	Rez, L.	PDF	N/A	Stem water content is crucial to support fruit tree functioning during heatwaves in a Mediterranean climate
野生葡萄品种对气候变化的适应动态有助于培育具有气候适应性的葡萄及其砧木。	Zhang, M.	PDF	N/A	The dynamics of wild Vitis species in response to climate change facilitate the breeding of grapevine and its rootstocks with climate resilience
整合耐寒性和抗去驯化能力表明葡萄藤对寒冷积累的保守反应。	Londo, J. P.	PDF	N/A	Integrating cold hardiness and deacclimation resistance demonstrates a conserved response to chilling accumulation in grapevines.
利用自然低氧应答因子设计的反馈机制增强了合成低氧生物传感器	Dreyer, K. S.	PDF	N/A	Engineered Feedback Employing Natural Hypoxia-Responsive Factors Enhances Synthetic Hypoxia Biosensors
氧化还原信号在脂肪组织分泌组中炎症细胞因子诱导的脂肪前体细胞分化中起介导作用	Wager, J. L.	PDF	N/A	Redox Signaling Mediates Differentiation of Adipose Progenitors in Response to Inflammatory Cytokines in the Adipose Tissue Secretome
艾森侧抑制任务中行为和电生理标记的重测信度和重复性	Bogdanov, M.	PDF	N/A	Test-Retest Reliability and repeatability of Behavioral and Electrophysiological Markers in an Eriksen Flanker Task
评估基于头皮的DLPFC定位方法用于TMS治疗：EEG帽F3、光束F3、CPC F3及调整后的光束F3	Jiang, Y.	PDF	N/A	Evaluation of scalp-based targeting methods of DLPFC for TMS therapy: EEG cap F3, Beam F3, CPC F3, and adjusted Beam F3
系统性催产素和β3受体激动剂（CL 316243）治疗对雄性饮食诱导肥胖大鼠体重和脂肪含量的影响	Slattery, J. D.	PDF	N/A	Effects of systemic oxytocin and beta-3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet-induced obese rats
利用扩散磁共振成像技术在体内绘制人脑皮层微观结构图	Sadikov, A.	PDF	N/A	Mapping the Microstructure of Human Cerebral Cortex In Vivo with Diffusion MRI
状态和特质血清素变化相互作用，塑造了大脑的内在连接性和梯度结构：一项结合TPH2遗传学和色氨酸耗竭的研究	Wang, L.	PDF	N/A	State and trait serotonin variations interact to shape the intrinsic connectivity and gradient architecture of the brain: a combined TPH2 genetics and tryptophan depletion study
元控制状态的神经生理动力学：脑电图对冲突调节的洞察	Wang, X.	PDF	N/A	Neurophysiological Dynamics of Metacontrol States: EEG Insights into Conflict Regulation
雄性小鼠在寻求奖励过程中伏隔核神经元的时序动力学	Schall, T. A.	PDF	N/A	Temporal Dynamics of Nucleus Accumbens Neurons in Male Mice During Reward Seeking
左旋多巴在体外损害感觉神经元的溶酶体功能	Olaoye, O. J.	PDF	N/A	Levodopa impairs lysosomal function in sensory neurons in vitro
人类CaV2.1通道的可用性背后隐藏着丰富的构象多样性。	Wang, K.	PDF	N/A	A rich conformational palette underlies human CaV2.1-channel availability
靶向组织的初免/加强/维持治疗性单纯疱疹病毒疫苗保护HLA-A*0201转基因兔免受复发性眼部疱疹疾病的侵害	Chentoufi, A.	PDF	N/A	Tissue-Targeted Prime/Pull/Keep Therapeutic Herpes Simplex Virus Vaccine Protect Against Recurrent Ocular Herpes Diseases in HLA-A*0201 Transgenic Rabbits
探索UVB敏感性与系统性红斑狼疮活动性之间的关联：深入了解紫外线B驱动的红斑狼疮发病机制	He, J.	PDF	N/A	Exploring the Correlation Between UVB Sensitivity and SLE Activity: Insights into UVB-Driven Pathogenesis in Lupus Erythematosus
缺氧条件下的效应T细胞具有与非应答性黑色素瘤患者中发现的肿瘤应激T细胞相似的转录组改变。	Nagy, M. Z.	PDF	N/A	Effector T Cells under Hypoxia have an Altered Transcriptome Similar to Tumor-Stressed T Cells Found in Non-Responsive Melanoma Patients
体内T细胞共调节因子B7-H4的成像揭示了前列腺癌中的促肿瘤巨噬细胞状态	Kumar, M.	PDF	N/A	In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer
利用新型自噬体分离方法对饥饿和运动期间自噬货物谱的表征	Liu, Y.	PDF	N/A	Characterization of Autophagy Cargo Profiles during Starvation and Exercise with a Novel Autophagosome Isolation Method
结肠炎症的性别差异是由上皮特异性表达的雌激素受体α驱动的。	Pereda, G. A.	PDF	N/A	Sex differences in colonic inflammation are driven by epithelial-specific expression of estrogen receptor alpha
利用cardiodeleter系统优化快速且稳健地生成斑马鱼心肌细胞特异性crispr的方法	Keeley, S.	PDF	N/A	Optimization of methods for rapid and robust generation of cardiomyocyte-specific crispants in zebrafish using the cardiodeleter system
全球模式、驱动因素及羊膜动物代谢特征的影响	Yang, Q.	PDF	N/A	Global patterns, drivers and impacts of metabolic traits across amniotes
早期人属生物进入东南亚地区引发了主要人类疟疾病媒的进化。	Singh, U. S.	PDF	N/A	Early hominin arrival in Southeast Asia triggered the evolution of major human malaria vectors
高吞吐量靶向扩增子筛选工具，用于直接从样本中表征金黄色葡萄球菌宿主内多样性	Furstenau, T. N.	PDF	N/A	High-throughput targeted amplicon screening tool for characterizing intrahost diversity in Staphylococcus aureus directly from sample
微流体法制备的超薄、可操作胶原蛋白片材表现出趾跟拉伸行为	Zhang, Y.	PDF	N/A	Microfluidic Formation of Ultrathin, Handleable Collagen Sheets Exhibiting Toe-heel Tensile Behavior
依赖于浓度的CsrA对uxuB转录本的调控导致转录后BANDPASS滤波器的形成	Rojano-Nisimura, A. M.	PDF	N/A	Concentration dependent CsrA regulation of the uxuB transcript leads to development of post-transcriptional BANDPASS Filter
追踪骨细胞衰老：骨细胞细胞骨架力学和形态的时变变化	Liao, J.	PDF	N/A	Tracing Cellular Senescence in Bone: Time-Dependent Changes in Osteocyte Cytoskeleton Mechanics and Morphology
环氧合酶-2的破坏易导致保留射血分数的心力衰竭	Ricciotti, E.	PDF	N/A	Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction
以非蛋白质氨基酸为测试案例，采用一种新的化学分类学方法	Gibson, M.	PDF	N/A	A new spin on chemotaxonomy using non-proteogenic amino acids as a test case
成年创伤性脑损伤后，使用脂多糖进行免疫挑战会迅速改变神经炎症和肠道微生物群，但对慢性结果影响甚微。	Rewell, S. S. J.	PDF	N/A	A post-injury immune challenge with lipopolysaccharide following adult traumatic brain injury alters neuroinflammation and the gut microbiome acutely, but has little effect on chronic outcomes
初级视觉皮层中视觉空间的深度图	He, Y.	PDF	N/A	A depth map of visual space in the primary visual cortex
在循环网络中，序列神经活动的自发涌现与漂移	Shao, S.	PDF	N/A	Spontaneous emergence and drifting of sequential neural activity in recurrent networks
解读激活和共刺激抗体在纳米尺度聚集对T细胞激活的作用	Le Saux, G.	PDF	N/A	Deciphering the role of the nanoscale clustering of activating and costimulatory antibodies on T cell activation
利用CRISPR激活技术快速评估人类多能干细胞中的基因编辑产物	Wu, Y.	PDF	N/A	Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells
利用时间动力学的定量相位成像预测造血干细胞的多样性	Yogo, T.	PDF	N/A	Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity
多用途动态体积生物成像的多功能光场显微平台	Bai, Y.	PDF	N/A	A Versatile Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bio-imaging
冠蜥（Correlophus ciliatus）染色体水平基因组组装与注释：一种无法再生尾巴的蜥蜴	Gumangan, M.	PDF	N/A	Chromosome-level genome assembly and annotation of the crested gecko, Correlophus ciliatus, a lizard incapable of tail regeneration
改善土壤中病毒的可视化	Parvate, A. D.	PDF	N/A	Improving the visualization of viruses in soil
铜绿微囊藻暴露于大薸和水葫芦水提液的生理响应	Silva, L. d. O.	PDF	N/A	Physiological response of Microcystis aeruginosa exposed to aqueous extracts of Pistia stratiotes and Pontederia crassipes
一种前所未有的微小RNA-核开关相互作用控制着一种双功能泵的表达，这种泵对金黄色葡萄球菌感染至关重要。	Gonzalez-Espinoza, G.	PDF	N/A	An unprecedented small RNA-riboswitch interaction controls expression of a bifunctional pump that is essential for Staphylococcus aureus infection
嗜热绿弯菌外膜小泡可能是生物硫运输的重要途径。	Noundou, V. L.	PDF	N/A	Chlorobaculum tepidum Outer Membrane Vesicles Are Likely a Significant Route for Biogenic Sulfur Transport.
饮食中的L-3,4-二羟基苯丙氨酸（L-DOPA）增强了按蚊外骨骼的黑色素化，同时缩短了它们的寿命并减少了疟原虫的负担。	Camacho, E.	PDF	N/A	Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in Anopheles mosquitos while reducing their lifespan and malaria parasite burden
普拉梭菌调节C57BL/6小鼠肠道微生物群的碳水化合物代谢功能	Geng, P.	PDF	N/A	Faecalibacterium prausnitzii regulates carbohydrate metabolic functions of the gut microbiome in C57BL/6 mice
长读宏基因组学能够精确追踪细菌菌株及其在粪菌移植后的基因组变化。	Fan, Y.	PDF	N/A	Long-read metagenomics empowers precise tracking of bacterial strains and their genomic changes after fecal microbiota transplantation
新型抗碳青霉烯类肺炎克雷伯菌噬菌体的特性分析	Kim, B.	PDF	N/A	Characterization of newly isolated bacteriophages targeting carbapenem-resistant Klebsiella pneumoniae
在2019年至2021年间，法国诺曼底地区解剖的马科动物中，艰难梭菌的感染情况：产毒菌株的普遍携带及新兴的017型菌株的毒力	Petry, S.	PDF	N/A	Clostridioides difficile in Equidae necropsied in Normandie, France from 2019 to 2021: common carriage of toxigenic strains and virulence of emerging ribotype 017
Typhi Mykrobe：直接从序列读取中快速且准确地识别伤寒沙门氏菌的谱系及抗菌药物耐药性基因分型	Ingle, D. J.	PDF	N/A	Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent Salmonella Typhi
两个跨膜转录调节因子协同作用，激活了霍乱弧菌中由几丁质诱导的自然转化过程。	Hullinger, A. C.	PDF	N/A	Two transmembrane transcriptional regulators coordinate to activate chitin-induced natural transformation in Vibrio cholerae
二萜类植物抗毒素塑造了水稻根系微生物群及其与根寄生线虫的关联	Kudjordjie, E. N.	PDF	N/A	Diterpenoid phytoalexins shape rice root microbiomes and their associations with root parasitic nematodes
一项针对多种土壤类型和地理区域抗生素抗性的宏基因组研究	Pillay, S.	PDF	N/A	A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations
一种宿主导向的佐剂可复苏并增强抗生素对胞内细菌持留菌的敏感性。	Lu, K.-Y.	PDF	N/A	A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics
NPC1L1介导的27-羟基胆固醇代谢在骨质疏松发生发展中的机制	Li, B.	PDF	N/A	Mechanism of NPC1L1 mediated 27-hydroxycholesterol metabolisms in the occurrence and development of osteoporosis
生物固体改良对土壤抗性组和微生物组的影响 - 温室研究	Ste.Marie, J. P.	PDF	N/A	Impact of biosolids amendment on the soil resistome and microbiome - a greenhouse study
一种用于心脏特异性基因沉默的腺嘌呤碱基编辑器的多功能AAV载体	Liu, Z.	PDF	N/A	An all-in-one AAV vector for cardiac-specific gene silencing by an adenine base editor
伏隔核电刺激后脑分子景观的变化	Cai, C.	PDF	N/A	Change in brain molecular landscapes following electrical stimulation of the nucleus accumbens
马洛：利用从头肽段鉴定技术对法医学中的未知样本进行分类表征	Jenson, S. C.	PDF	N/A	MARLOWE: Taxonomic Characterization of Unknown Samples for Forensics Using De Novo Peptide Identification
高通量多样化蛋白质-配体表面以发现化学诱导接近剂	Shaum, J. B.	PDF	N/A	High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity
体内碘代酪氨酸尿代谢物的鉴定与测定	Ji, C. X.	PDF	N/A	Identification and determination of the urinary metabolite of iodotyrosine in vivo
甲烷产生古菌Methanococcus maripaludis中的糖原磷酸化酶：一种不依赖吡哆醛5'-磷酸的磷酸化酶的独特调节特性	Gonzalez-Ordenes, F.	PDF	N/A	Glycogen phosphorylase from the methanogenic archaeon Methanococcus maripaludis: Unique regulatory properties of a pyridoxal 5'-phosphate independent phosphorylase
持续性和爆发性电微刺激对皮层兴奋性和抑制性神经元激活的时空特性	Hughes, C.	PDF	N/A	Spatiotemporal properties of cortical excitatory and inhibitory neuron activation by sustained and bursting electrical microstimulation
基于核酶的生物传感器用于植物基因表达成像	Liu, Y.	PDF	N/A	Ribozyme-based biosensor for imaging gene expression in plants
以线粒体为中心的包涵体肌炎代谢组图谱：中心碳代谢的性别特异性改变	Naddaf, E.	PDF	N/A	Mitochondria-centered metabolomic map of inclusion body myositis: sex-specific alterations in central carbon metabolism
将地理空间工具整合于绘制坦桑尼亚鲁索托西乌桑巴拉山森林火灾严重程度和烧毁区域图	Mkiwa, B. P.	PDF	N/A	Integrating geospatial tools in mapping forest fire severity and burned areas in the Western Usambara Mountain Forests, Lushoto, Tanzania
FIGL1限制了拟南芥中减数分裂非交叉事件的形成	Charif, D.	PDF	N/A	FIGL1 limits the formation of meiotic non crossover events in Arabidopsis thaliana
一种导致常染色体显性肥厚型心肌病的ALPK3截短变异体通过马瓦卡姆汀部分得到挽救	Leinhos, L.	PDF	N/A	An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten
通过多巴胺交联稳定模拟胶原蛋白三螺旋及其组装结构	Cole, C. C.	PDF	N/A	Covalent Stabilization of Collagen Mimetic Triple Helices and Assemblies by Dopa Crosslinking
组织特异性和空间依赖性的代谢特征在骨骼成熟的雄性和雌性C57Bl/6J小鼠中因损伤而受到干扰	Welhaven, H. D.	PDF	N/A	Tissue-specific and spatially dependent metabolic signatures perturbed by injury in skeletally mature male and female C57Bl/6J mice
恶性疟原虫NCR1膜蛋白是一种新型抗疟疾靶点，负责将胆固醇输出以维持膜稳态。	Zhang, Z.	PDF	N/A	The Plasmodium falciparum NCR1 membrane protein is a novel antimalarial target that exports cholesterol to maintain membrane homeostasis
选择性波段红外脉冲回波光谱（Band-selective IR PRESS）用于脑肿瘤光谱分析，能够稳健地检测乳酸。	Kishimoto, S.	PDF	N/A	Band-selective IR PRESS for brain tumor spectroscopy allows robust detection of lactate
R2DT：一个用于可视化RNA二级结构的全面平台	McCann, H.	PDF	N/A	R2DT: a comprehensive platform for visualising RNA secondary structure
早期呼吸道合胞病毒感染对特定细胞类型气道DNA甲基化的影响	McKennan, C.	PDF	N/A	Impact of early-life respiratory syncytial virus infection on cell type-specific airway DNA methylation
# BioRxiv 2024-09-29 Papers

标题	作者	PDF链接	代码仓库	Title
后顶叶皮层中的分隔树突可塑性整合了跨越时间的记忆	Sehgal, M.	PDF	N/A	Compartmentalized dendritic plasticity in the retrosplenial cortex integrates memories across time
呼叫模式在狨猴中编码和传递情感	Huang, J.	PDF	N/A	Call patterns encode and transmit emotion in marmoset monkeys
活跃的树突能够在时间抖动的情况下实现鲁棒的尖峰计算	Burger, T. S.	PDF	N/A	Active Dendrites Enable Robust Spiking Computations despite Timing Jitter
AAA+蛋白Msp1通过疏水性错配识别底物。	Fresenius, H. L.	PDF	N/A	The AAA+ protein Msp1 recognizes substrates by a hydrophobic mismatch
氯霉素和庆大霉素通过抑制大肠杆菌C LPS突变体的一个子集，减少了噬菌体{Phi}X174的抗性进化。	Parab, L.	PDF	N/A	Chloramphenicol and gentamicin reduce resistance evolution to phage {Phi}X174 by suppressing a subset of E. coli C LPS mutants
KaryoTap 实现数千个单个人类细胞的非整倍体检测	Mays, J. C.	PDF	N/A	KaryoTap Enables Aneuploidy Detection in Thousands of Single Human Cells
将恐惧重新引入边际价值理论：风险-边际价值理论与最佳胆量	Calcagno, V.	PDF	N/A	Taking fear back into the Marginal Value Theorem: the risk-MVT and optimal boldness
定量全基因组模型揭示可解释的全基因组关联	Ruzickova, N.	PDF	N/A	Quantitative omnigenic model discovers interpretable genome-wide associations
上皮力学的贝叶斯参数推断	Yan, X.	PDF	N/A	Bayesian parameter inference for epithelial mechanics
特定的有丝分裂事件驱动细胞骨架重塑，这是左右器官发育所必需的	Wu, Y.	PDF	N/A	Specific Mitotic Events Drive Cytoskeletal Remodeling Required for Left-Right Organizer Development
级联反向积分反馈基序用于提高鲁棒稳定性和性能	M. Zand, A.	PDF	N/A	Cascaded Antithetic Integral Feedback Motifs for Robust Stability and Performance Improvement
Lphn1敲除抑制结直肠癌机制的研究	wang, Y.	PDF	N/A	Research on the Mechanism of Lphn1 Knockout in Inhibiting Colorectal Cancer
果蝇母体向合子转变过程中先锋因子结合动力学的批量级图谱	Dima, S. S.	PDF	N/A	Bulk-level maps of pioneer factor binding dynamics during Drosophila maternal-to-zygotic transition
猴子预测美国大选	Jiang, Y.	PDF	N/A	Monkeys Predict US Elections
波兰乳牛中分离出的多杀性巴氏杆菌和溶血性曼海姆菌的抗菌药物抗性和毒力相关基因，这些乳牛表现出牛呼吸道疾病的症状	Lachowicz-Wolak, A.	PDF	N/A	Antimicrobial Resistance and Virulence-Associated Genes of Pasteurella multocida and Mannheimia haemolytica Isolated from Polish Dairy Calves with Symptoms of Bovine Respiratory Disease
视觉雪花综合征患者的定向运动敏感性受到拖尾型后像存在的影响而发生调节。	Obukhova, T. S.	PDF	N/A	Directional motion sensitivity in people with Visual Snow Syndrome is modulated by the presence of trailing-type palinopsia
在人为影响下的农产品中发现了“不为人知”的抗生素抗性	Davidovich, C.	PDF	N/A	Occurrence of "under-the-radar" antibiotic resistance in anthropogenically affected produce
CCR5拮抗剂作为神经保护和卒中恢复增强剂：一项临床前系统评价和荟萃分析	Sharif, A.	PDF	N/A	CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis
解开睫状衣：睫状糖萼的高分辨率结构与功能	Hoepfner, L. M.	PDF	N/A	Unwrapping the ciliary coat: high-resolution structure and function of the ciliary glycocalyx
连接酶介导的可编程基因组整合（L-PGI）：一种克服逆转录酶为基础的编辑系统局限性的高效位点特异性基因编辑系统	Nan, A. X.	PDF	N/A	Ligase-mediated programmable genomic integration (L-PGI): an efficient site-specific gene editing system that overcomes the limitations of reverse transcriptase-based editing systems
母亲行为的自然变化会影响后代特质焦虑和海马神经发生	Grieco, F.	PDF	N/A	Natural variations in maternal behaviour shape trait anxiety and hippocampal neurogenesis in offspring
Dnmt1在腹侧苍白球中间神经元中的缺失会改变皮层回路功能，并导致类似抑郁的行为。	Linde, J.	PDF	N/A	Dnmt1-deficiency in PV interneurons alters cortical circuit function and leads to depression-like behavior
评估美国模拟非洲猪瘟疫情中的采样和实验室能力	Galvis, J. A.	PDF	N/A	Estimating sampling and laboratory capacity for a simulated African swine fever outbreak in the United States
利用金属诱导能量转移成像/光谱技术测量活细胞中膜的三维动力学	Chen, T.	PDF	N/A	Measuring 3-dimensional dynamics of membrane in living cell with metal-induced energy transfer imaging/spectroscopy
安非他命通过破坏前额叶的渐进活动来增加时间变异性。	Weber, M. A.	PDF	N/A	Amphetamine increases timing variability by degrading prefrontal ramping activity
HIV感染和治疗中免疫细胞的代谢重编程	Wu, D.	PDF	N/A	Metabolic reprogramming of immune cells in HIV infection and treatment
结核分枝杆菌在病原体特异性免疫下生存的遗传需求	James, K. S.	PDF	N/A	Genetic requirements of Mycobacterium tuberculosis for survival under pathogen-specific immunity
跨王国互动与环境对重度低龄儿童龋齿口腔微生物群的影响	Weng, L.	PDF	N/A	Inter-Kingdom Interactions and Environmental Influences on the Oral Microbiome in Severe Early Childhood Caries
功能性状预测了在气候变暖条件下当前和新颖竞争的结果	Lyu, S.	PDF	N/A	Functional traits predict outcomes of current and novel competition under warmer climate
mTORC1和STAT3信号通路对于体外TGFβ1依赖的三维（3D）肌腱构建体的形成是不可或缺的。	Koo, B.	PDF	N/A	mTORC1 and STAT3 signalings are indispensable for in vitro TGFβ1-dependent Three-Dimensional (3D) tendon construct.
p53Y217C的致癌和致畸效应，这是一种模拟人类热点突变p53Y220C的小鼠模型	Jaber, S.	PDF	N/A	Oncogenic and teratogenic effects of p53Y217C, a mouse model of the human hotspot mutant p53Y220C
透明细胞肾细胞癌肿瘤血栓相关mRNA可变剪接的特征分析	Cohen, Z.	PDF	N/A	Characterization of alternative mRNA splicing associated with tumor thrombus in clear-cell renal cell carcinoma
癌症中热力学失稳酪氨酸磷酸化的快速预测	Woodard, J. C.	PDF	N/A	Rapid prediction of thermodynamically destabilizing tyrosine phosphorylations in cancers
大麻烟雾和口服Δ9THC能增强老年受试者的工作记忆，但对年轻成年受试者则无此效果。	Zequeira, S.	PDF	N/A	Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects
洞穴适应有利于墨西哥脂鲤的衰老韧性	Cobham, A. E.	PDF	N/A	Cave Adaptation Favors Aging Resilience in the Mexican Tetra
敲除SfVipR1基因可使甜菜夜蛾对苏云金芽孢杆菌Vip3Aa毒素产生高水平抗性。	Zhang, Z.	PDF	N/A	Knockout of the SfVipR1 gene confers high-level resistance to Bacillus thuringiensis Vip3Aa toxin in Spodoptera frugiperda
衰老的食管上皮细胞中，先前的NOTCH1突变改变了体细胞突变的选择。	Jones, P. H.	PDF	N/A	Somatic mutant selection is altered by prior NOTCH1 mutation in aging esophageal epithelium
软骨下骨髓脂肪组织脂解作用调控手骨关节炎中的骨形成	Maniglio, M.	PDF	N/A	Subchondral bone marrow adipose tissue lipolysis regulates bone formation in hand osteoarthritis
代谢应激加速了骨关节炎中失调的滑膜巨噬细胞-成纤维细胞通讯及Htra1的过度产生	Blackler, G.	PDF	N/A	Metabolic Stress Accelerates Dysregulated Synovial Macrophage-Fibroblast Communication and Htra1 Overproduction in Osteoarthritis
延长IKK激活的时间变化刺激促进了核重塑和NF-κB动力学的机制转换	Smeal, S. W.	PDF	N/A	Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics
旁系同源蛋白补偿在癌症中基因丢失后维持蛋白质相互作用网络	Venkatesh, A.	PDF	N/A	Paralog protein compensation preserves protein-protein interaction networks following gene loss in cancer
增强型AAV工具箱，用于访问和扰动纹状体细胞类型及回路	Hunker, A. C.	PDF	N/A	Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits
分子与神经回路机制：果蝇性经验依赖的长时记忆	Sun, D.	PDF	N/A	Molecular and Neural Circuit Mechanisms Underlying Sexual Experience-dependent Long-Term Memory in Drosophila.
青年时期个性化功能网络地形中可重复的性别差异	Keller, A. S.	PDF	N/A	Reproducible Sex Differences in Personalized Functional Network Topography in Youth
用于评估啮齿动物前肢功能的运动偏差指数（KDI）	Espin, A. T.	PDF	N/A	A Kinematic Deviation Index (KDI) for Evaluation of Forelimb Function in Rodents
同源异型结构域蛋白编码在果蝇视觉系统的第一神经节中规定了神经元的多样性	Xu, C.	PDF	N/A	Homeodomain protein codes specify neuronal diversity in the first ganglion of the Drosophila visual system
人类乳腺癌中转座元件的可变剪接	Nesta, A. V.	PDF	N/A	Alternative splicing of transposable elements in human breast cancer
EmbedSimScore：通过结构和上下文嵌入推进蛋白质相似性分析	Saha, G.	PDF	N/A	EmbedSimScore: Advancing Protein Similarity Analysis with Structural and Contextual Embeddings
果蝇在特征贫乏环境中的空间学习	Chen, Y.	PDF	N/A	Spatial learning in feature-impoverished environments in Drosophila
绘制并构建多相核仁的RNA调控结构	Quinodoz, S. A.	PDF	N/A	Mapping and engineering RNA-controlled architecture of the multiphase nucleolus
微流控调节显微解剖肿瘤中的微血管	Nguyen, T. N. H.	PDF	N/A	Microfluidic Modulation of Microvasculature in Microdissected Tumors
柠檬黄不能使活体组织变得透明	Inagaki, S.	PDF	N/A	Tartrazine cannot make live tissues transparent
ABA调控的JAZ1蛋白通过结合NAC42转录因子抑制植物中植保素生物合成的激活	Lin, J.	PDF	N/A	ABA-regulated JAZ1 Proteins Bind NAC42 Transcription Factors to Suppress the Activation of Phytoalexin Biosynthesis in Plants
生物学启发的皮层模型预测光遗传学扰动	Sourmpis, C.	PDF	N/A	Biologically informed cortical models predict optogenetic perturbations
运动检测任务中的目标与干扰项的节奏采样与竞争	Xiong, C.	PDF	N/A	Rhythmic Sampling and Competition of Target and Distractor in a Motion Detection Task
病毒性流行病的潜在风险在蝙蝠的系统发育树上并非均匀分布	Cummings, C. A.	PDF	N/A	Viral epidemic potential is not uniformly distributed across the bat phylogeny
无目标的CUT&Tag和BG4 CUT&Tag均在G四链体和可接近的染色质区域富集。	Thompson, M. D.	PDF	N/A	Untargeted CUT&Tag and BG4 CUT&Tag are both enriched at G-quadruplexes and accessible chromatin
用于引导组织组织和再生的具有微观形貌的多尺度支架的3D打印	Fu, R.	PDF	N/A	3D Printing of Multiscale Scaffolds with Microtopography for Guiding Tissue Organization and Regeneration
使用从人脑死后组织中分离的微血管构建的解剖学和生理学上准确的工程化神经血管单元和血脑屏障模型	O'Grady, B.	PDF	N/A	Anatomically and Physiologically Accurate Engineered Neurovascular Unit and Blood-Brain Barrier Model Using Microvessels Isolated from Postmortem Human Brain Tissue
使用单细胞多组学数据集对拷贝数畸变推断工具进行基准测试	Song, M.	PDF	N/A	Benchmarking copy number aberrations inference tools using single-cell multi-omics datasets
研究超声驱动激励微泡产生的复杂微流场中剪切应力下的细胞活力	Bakhtiari, A.	PDF	N/A	Investigating Cell Viability under Shear Stress in Complex Microstreaming Flows Generated by Ultrasound-Driven Actuated Microbubbles
异常血管系统减少了肿瘤计算模型中药物与氧气的重叠：对治疗效果的影响	Enjalbert, R.	PDF	N/A	Abnormal vasculature reduces overlap between drugs and oxygen in a tumour computational model: implications for therapeutic efficacy
没有超螺旋扭曲的胶原蛋白三螺旋	Kreutzberger, M. A. B.	PDF	N/A	A Collagen Triple Helix without the Super Helical Twist
经过田间试验的HaHB11和HaHB4大豆品种表现出增加的籽粒数量和在生殖阶段增强的耐热性。	Raineri, J.	PDF	N/A	Field-tested HaHB11 and HaHB4 soybean exhibit increased grain number and heat tolerance at the reproductive stage
通过比较不同行为群体的雄性和雌性个体，高估了性差异在精神兴奋剂活性中的作用。	Tigano, A. M.	PDF	N/A	Overestimation of sex differences in psychostimulant activity via comparisons of males and females from different behavioral groups.
AMPK激动剂优化了嵌合抗原受体T细胞在体内的持久性和抗白血病疗效。	Braverman, E.	PDF	N/A	AMPK agonism optimizes the in vivo persistence and anti-leukemia efficacy of chimeric antigen receptor T cells
用于昆虫运动中肢体运动学本体感觉的尖峰神经网络模型	van der Veen, T.	PDF	N/A	A spiking neural network model for proprioception of limb kinematics in insect locomotion
在存在竞争性细菌病原体的情况下进行噬菌体引导	Gurney, J.	PDF	N/A	Phage Steering in the Presence of a Competing Bacterial Pathogen
硝唑酮通过DNA损伤和应激反应途径对棘阿米巴卡氏虫具有杀阿米巴活性	Chen, L.	PDF	N/A	Nitroxoline evidence Amoebicidal Activity against Acanthamoeba castellanii through DNA damage and the stress response pathways
流感病毒感染细胞的病毒液滴中，段间相互作用的形成依赖于浓度	Takizawa, N.	PDF	N/A	Concentration-dependent formation of intersegment interactions in viral droplets of influenza A virus infected cells
体外研究洛雷斯坦特有植物阿月浑子叶水醇提取物的化学成分及抗龋齿细菌的抗菌活性	Rahimi, M.	PDF	N/A	In vitro study of chemical compositions and antibacterial activity of Lorestan endemic plant, Pistacia atlantica leaf hydroalcoholic extract against cariogenic bacteria
组蛋白残基H3K56与错配修复蛋白MutSβ之间的相互作用驱动CAG重复序列的扩展	Guo, J.	PDF	N/A	Interaction between histone residue H3K56 and mismatch repair protein MutSβ drives CAG repeat expansion
VirtualIce: 半合成冷冻电镜显微图生成器	Noble, A. J.	PDF	N/A	VirtualIce: Half-synthetic CryoEM Micrograph Generator
H3K9甲基化非依赖性活性在异染色质焦点、基因抑制和器官发生中的HPL-2/HP1作用	Delaney, C. E.	PDF	N/A	H3K9 methylation-independent activity for HPL-2/HP1 in heterochromatin foci, gene repression, and organogenesis
近端H3K14泛素化对组蛋白H3K9甲基转移酶Clr4的刺激机制探究	Du, Y.	PDF	N/A	Mechanistic Insights into the Stimulation of the Histone H3K9 Methyltransferase Clr4 by Proximal H3K14 Ubiquitination
拟南芥减数分裂中MutL复合体的遗传解剖	Kbiri, N.	PDF	N/A	Genetic dissection of MutL complexes in Arabidopsis meiosis
对跨越生命树的118,065个基因组中的发夹环和十字形结构进行特征分析	Chantzi, N.	PDF	N/A	Characterization of hairpin loops and cruciforms across 118,065 genomes spanning the tree of life
Sirtuin 6是一种组蛋白去乙酰化酶。	Nickel, G. A.	PDF	N/A	Sirtuin 6 is a histone delactylase
FID与否：在HPC中应用GANs进行MRI图像生成	Cepa, B.	PDF	N/A	To FID or not to FID: Applying GANs for MRI Image Generation in HPC
计算机模拟识别和建模针对T型钙通道的FDA批准药物	Pedro, F.	PDF	N/A	In Silico identification and modelling of FDA-approved drugs targeting T-type calcium channels
谷氨酸盐转运蛋白和代谢酶是浸润性乳腺小叶癌的不良预后因素	Young, T. A.	PDF	N/A	Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma
GERMIN3在马铃薯中通过调节质膜孔门的开关，参与调控与块茎形成、块茎休眠释放及茎分枝相关的分生组织激活过程。	Campbell, R.	PDF	N/A	GERMIN3 plays a role in plasmodesmatal gating to regulate meristem activation related to tuberisation, tuber dormancy release and stem branching in potato
比较组织特异性转录组学揭示了两个独立进化的稻属杂草谱系中种子脱粒进化趋同的遗传基础	Li, X.	PDF	N/A	Comparative tissue-specific transcriptomics reveal the genetic bases underlying evolutionary convergence of seed shattering in two independently evolved weedy rice lineages
鉴定孤儿作物Gynandropsis gynandra中的农艺、营养和叶脉数量性状位点	Simpson, C. J. C.	PDF	N/A	Identifying Agronomic, Nutrition and Leaf Vein Quantitative Trait Loci in the Orphan Crop Gynandropsis gynandra
碳源-汇反馈对植物生长对环境因素响应的影响	Friend, A. D.	PDF	N/A	Implications of carbon source-sink feedbacks for plant growth responses to environmental factors
微胶质细胞中肌动蛋白解聚因子ADF/Cfl1的缺乏会降低其迁移能力并损害记忆功能。	Crux, S.	PDF	N/A	Deficiency of actin depolymerizing factors ADF/Cfl1 in microglia decreases motility and impairs memory
星形胶质细胞衍生的PEA116增强了成年海马神经发生，并赋予了抗压能力	Carron, C.	PDF	N/A	Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience
由CD28或4-1BB共刺激驱动的平衡CAR-T细胞代谢与淋巴瘤患者的临床成功相关	Cook, M.	PDF	N/A	A balanced CAR-T cell metabolism driven by CD28 or 4-1BB co-stimulation correlates with clinical success in lymphoma patients
在囊性纤维化儿童新发感染中分离出的铜绿假单胞菌菌株中，逃避中性粒细胞介导的细菌清除	Kwong, K.	PDF	N/A	Evasion of neutrophil-mediated bacterial clearance in Pseudomonas aeruginosa isolates from new-onset infections in cystic fibrosis children
古代环境DNA显示，在工业化前的冰岛，人类对海洋生物多样性的影响有限。	Holman, L. E.	PDF	N/A	Ancient environmental DNA indicates limited human impact on marine biodiversity in pre-industrial Iceland
哺乳动物全血中的激进蛋白质足迹分析	Tobin, L.	PDF	N/A	Radical Protein Footprinting in Mammalian Whole Blood
在不进行数据整合的情况下，识别独立单细胞研究中的相似群体	Gonzalez-Velasco, O.	PDF	N/A	Identifying similar populations across independent single cell studies without data integration
质粒接合驱动患者内部质粒多样性	Grayson, F.	PDF	N/A	Plasmid conjugation drives within-patient plasmid diversity
gLinDA：微生物群的全球差异丰度分析	Fehse, L.	PDF	N/A	gLinDA: global differential abundance analysis ofmicrobiomes
stFormer：一种用于空间转录组学的基础模型	Cao, S.	PDF	N/A	stFormer: a foundation model for spatial transcriptomics
核纤层网络通过被动响应主动或被动的细胞运动来适应限制环境。	Amiri, S.	PDF	N/A	The nuclear lamin network passively responds to both active or passive cell movement through confinements
Pexidartinib联合FLT3定向CAR-巨噬细胞在FLT3-ITD突变急性髓系白血病临床前模型中的治疗研究	Chen, F.	PDF	N/A	Pexidartinib plus FLT3-directed CAR-Macrophage for the treatment of FLT3-ITD-mutated acute myeloid leukemia in preclinical model
CPK3介导的bHLH107胞质-核转位招募HY5以调节Cu2+触发的ACS8上调	Yu, Y.	PDF	N/A	CPK3-mediated cytosolic-nuclear translocation of bHLH107 recruits HY5 to regulate the Cu2+-triggered upregulation of ACS8
通过分布式本体感受实现行走和攀爬昆虫的运动原语和身体姿态编码	van der Veen, T.	PDF	N/A	Encoding of movement primitives and body posture through distributed proprioception in walking and climbing insects
FASER：一种用于模拟STED显微镜中点扩散函数畸变的工具	Bancelin, S.	PDF	N/A	FASER: A TOOL TO SIMULATE PSF DISTORTIONS IN STEDMICROSCOPY
新西兰及其亚南极群岛的禽流感病毒监测在迁徙的海鸟中检测到了H1N9病毒，但未发现2.3.4.4b高致病性H5N1禽流感病毒。	Waller, S. J.	PDF	N/A	Avian influenza virus surveillance across New Zealand and its subantarctic islands detects H1N9 in migratory shorebirds, but not 2.3.4.4b HPAI H5N1
枕叶皮层的功能重组导致视觉注意信息在后顶叶皮层中的功能重组。	Yang, F.	PDF	N/A	Pulvinar perturbation causes functional reorganization of visual attentional information in posterior parietal cortex
Hurst指数作为发育中大脑抑制作用的标志	Nishio, M.	PDF	N/A	The Hurst exponent as a marker of inhibition in the developing brain
杏仁核中间神经元在联想学习和消退中的异质可塑性	Favila, N.	PDF	N/A	Heterogeneous plasticity of amygdala interneurons in associative learning and extinction
# BioRxiv 2024-09-28 Papers

标题	作者	PDF链接	代码仓库	Title
协调口手食物操作的皮层回路	An, X.	PDF	N/A	A cortical circuit for orchestrating oromanual food manipulation
针对β冠状病毒的嵌合免疫原的结构预测，以诱导靶向抗体	Simpson, J.	PDF	N/A	Structural prediction of chimeric immunogens to elicit targeted antibodies against betacoronaviruses
利用分布式光学传感器自动化昆虫生物多样性指标：在美国堪萨斯州农业系统中的评估	Rydhmer, K.	PDF	N/A	Automating an insect biodiversity metric using distributed optical sensors: an evaluation across Kansas, USA cropping systems
一个标准化、在线交付、临床适用的神经认知评估平台：WebNeuro	Williams, L. M.	PDF	N/A	A platform for standardized, online delivered, clinically applicable neurocognitive assessment: WebNeuro
SIMVI揭示了空间组学数据中的内在状态和空间诱导状态	Dong, M.	PDF	N/A	SIMVI reveals intrinsic and spatial-induced states in spatial omics data
有丝分裂染色质标记控制DNA损伤的不对称分离	Ferrand, J.	PDF	N/A	Mitotic chromatin marking governs asymmetric segregation of DNA damage
人类骨骼肌纤维异质性超越肌球蛋白重链	Moreno-Justicia, R.	PDF	N/A	Human skeletal muscle fiber heterogeneity beyond myosin heavy chains
NeuroMechFly v2，模拟成年果蝇的具身感觉运动控制	Wang-Chen, S.	PDF	N/A	NeuroMechFly v2, simulating embodied sensorimotor control in adult Drosophila
解释老年人舌尖现象：大脑功能、结构和灌注对老年人心肺健康的影响	Rahman, F.	PDF	N/A	Explaining tip-of-the-tongue experiences in older adults: contributions of brain function, structure, and perfusion in relation to older adults cardiorespiratory fitness
果蝇幼虫肠道中病原菌的高效清除需要Duox/TrpA1/Dh31和IMD途径的空间和时间协调。	Tleiss, F.	PDF	N/A	Spatial and temporal coordination of Duox/TrpA1/Dh31 and IMD pathways is required for the efficient elimination of pathogenic bacteria in the intestine of Drosophila larvae
CD44 在空气介导的细胞间信号传导中促进粘附相互作用。	Bowman, R. L.	PDF	N/A	CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling
视听音乐会表演能够同步观众的心率。	Czepiel, A. M.	PDF	N/A	Audio-visual concert performances synchronize an audience's heart rates
微眼跳选择性作为对象解码的判别特征	Nouri, S.	PDF	N/A	Microsaccade Selectivity as Discriminative Feature for Object Decoding
硫酸乙酰肝素结合调控HpARI蛋白家族在体内的半衰期	Colomb, F.	PDF	N/A	Heparan sulphate binding controls in vivo half-life of the HpARI protein family
哺乳动物腹侧苍白球在单细胞分辨率下的转录组图谱	Yang, L.	PDF	N/A	Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution
在稀疏数据中对排名列表富集评分进行分析，揭示了算法的权衡	Wenzel, A. T.	PDF	N/A	Profiling ranked list enrichment scoring in sparse data elucidates algorithmic tradeoffs
毛首鞭形线虫未知的系统发育定位、全基因组组装及基因组范围关联研究：一种引起鞭虫病的新型人感染物种，对阿苯达唑-伊维菌素敏感性较低	Baer, M. A.	PDF	N/A	Phylogenetic placement, whole genome assembly, and genome-wide association study of Trichuris incognita: a novel human-infecting species causing trichuriasis, with low sensitivity to albendazole-ivermectin
具有保形保证的功能蛋白质挖掘	Boger, R. S.	PDF	N/A	Functional protein mining with conformal guarantees
沙尘暴驱动的潜在病原体和抗生素抗性基因在东地中海地区的扩散	Erkorkmaz, B. A.	PDF	N/A	Dust storm-driven dispersal of potential pathogens and antibiotic resistance genes in the Eastern Mediterranean
DNA甲基化分析工具中Infinium MethylationEPIC v2.0与v1.0读数差异的影响及对人类群体表观遗传学研究的考量	Zhuang, B. C.	PDF	N/A	Discrepancies in readouts between Infinium MethylationEPIC v2.0 and v1.0 reflected in DNA methylation-based tools: implications and considerations for human population epigenetic studies
在启动子和增强子内的成簇κB位点之间的协同作用决定了NF-κB RelA的转录特异性，同时还有特定的共因子参与。	Shahabi, S.	PDF	N/A	Cooperativity among clustered κB sites within promoters and enhancers dictates transcriptional specificity of NF-κB RelA along with specific cofactors
一种能够穿越血脑屏障的神经肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了具有抗惊厥、神经保护和抗炎特性的药理性低体温。	Ferhat, L.	PDF	N/A	A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
急性全身照射对胸腺上皮细胞的第二次影响	Namiki, K.	PDF	N/A	Second impact of an acute total body irradiation on thymic epithelial cells
掌握神经影像分析中的伪影校正：回顾性方法	Oliveira, A.	PDF	N/A	Mastering Artifact Correction in Neuroimaging Analysis: A Retrospective Approach
内源性逆转录病毒位点及在日本本土鸡中诱导的基因表达变化	Ishihara, S.	PDF	N/A	Endogenous Retrovirus Loci and Induced Changes in Gene Expression in Japanese Indigenous Chickens
丰富的活跃社区成员响应温泉光合垫的昼夜周期	Shelton, A. N.	PDF	N/A	Abundant and active community members respond to the diel cycle in hot spring phototrophic mats
楚科奇海环斑海豹和髯海豹的丰度和分布：未来趋势的参考	Boveng, P. L.	PDF	N/A	Abundance and distribution of ringed and bearded seals in the Chukchi Sea: a reference for future trends
整合酶复合体亚基12敲除克服了逆转HIV潜伏性的转录阻滞	Gray, C. N.	PDF	N/A	Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal
像姐妹而非双胞胎——加压素和催产素通过细胞类型特异性表达的催产素受体激活BNST神经元，从而减少焦虑性觉醒。	Francesconi, W.	PDF	N/A	Like sisters but not twins - vasopressin and oxytocin excite BNST neurons via cell type-specific expression of oxytocin receptor to reduce anxious arousal
在心脏形成过程中，心包膜作为一个独立的结构形成。	Moran, H. R.	PDF	N/A	The pericardium forms as a distinct structure during heart formation
在加利福尼亚中部城市环境中越冬的穴居猫头鹰（Athene cunicularia hypugaea）到达较晚，离开较早，偏好有遮蔽的微生境，能够忍受雨水，并与多种捕食者竞争。	Nicolaus, M. A.	PDF	N/A	Athene cunicularia hypugaea wintering in a central California urban setting arrive later, leave earlier, prefer sheltered micro-habitat, tolerate rain, and contend with diverse predators
视网膜母细胞瘤蛋白（Rb）口袋结构域中与癌症相关的错义变异的结构和功能分析	Castro, A.	PDF	N/A	Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain
瞬态Notch激活促使多能干细胞衍生的心肌细胞向浦肯野纤维命运转变	Gonzalez, D. M.	PDF	N/A	Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate
一种用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱仪系统	bazargan, s.	PDF	N/A	A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets
解码mEos4b的日间成熟过程及工程化快速成熟变体	Maity, A.	PDF	N/A	Decoding mEos4b Day-Long Maturation and Engineering Fast Maturing Variants
缺血损伤后猪肾脏在常温机械灌注保存结束时，尽管功能未变，但代谢重编程并诱导移植后纤维化：来自肾脏蛋白质组的见解。	Mulvey, J. F.	PDF	N/A	End of preservation normothermic machine perfusion of porcine kidneys after ischaemic injury reprograms metabolism and induces fibrosis after transplant despite unchanged function: insights from the renal proteome.
系统发育基因组学和代谢工程揭示茄科植物中存在一个保守的甾体生物合成基因簇	Hakim, S. E.	PDF	N/A	Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
组织驻留记忆CD4+ T细胞的维持依赖于特定部位的自我更新水平以及来自前体的补充。	Chandler, J.	PDF	N/A	Tissue resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and replacement from precursors
通过味觉受体检测细菌可启动细胞免疫反应	Mazariegos, A. N.	PDF	N/A	Detection of bacteria through taste receptors primes the cellular immune response
活体秀丽隐杆线虫的器官特异性亲电应答图谱绘制	Liu, J.	PDF	N/A	Organ-specific electrophile responsivity mappingin live C. elegans
基于细胞的检测技术评分SARS-CoV-2核衣壳蛋白药物诱导凝聚的比较评估	Quek, R. T.	PDF	N/A	Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein
通过电子断层扫描技术对核糖体数量进行原位定量	El Hankouri, M.	PDF	N/A	In situ quantification of ribosome number by electron tomography
不同保护制度对西高止山脉木本植物多样性和组成的影响	Shigwan, B. K.	PDF	N/A	Effect of differential protection regimes on the diversity and composition of woody plants in the Western Ghats
描述与真菌病原体球孢子菌（Coccidioides immitis）相关的土壤微生物群落	Radosevich, M. T.	PDF	N/A	Characterizing the soil microbial community associated with the fungal pathogen Coccidioides immitis
陆地食草动物通过间接效应推动水生群落的适应性进化	Schaefer, M.	PDF	N/A	Terrestrial herbivory drives adaptive evolution in an aquatic community via indirect effects
四种酵母物种及其杂交种在极端温度条件下的长期进化潜力	Pinto, J.	PDF	N/A	The long-term evolutionary potential of four yeast species and their hybrids in extreme temperature conditions
反复的基因渐渗和地理分层塑造了新热带地区的酿酒酵母	Avelar-Rivas, J. A.	PDF	N/A	Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics
通过纳米孔长读长测序技术分析天然CpG甲基化，精细定位调控变异	Tian, Y.	PDF	N/A	Fine Mapping Regulatory Variants by Characterizing Native CpG Methylation with Nanopore Long Read Sequencing
核型I肌球蛋白对生命和基因组组织至关重要	Peng, A. Y. T.	PDF	N/A	Nuclear Type I Myosins are Essential for Life and Genome Organization
Integral-Omics：利用活检组织进行连续提取与代谢组、脂质组、基因组、转录组、全蛋白质组及磷酸化蛋白质组的分析与表征	Li, W.	PDF	N/A	Integral-Omics: serial extraction and profiling of metabolome, lipidome, genome, transcriptome, whole proteome and phosphoproteome using biopsy tissue
使用ROS/RNS条件蛋白质组学分析参与过氧亚硝酸盐稳态的蛋白质	Zhu, H.	PDF	N/A	Profiling proteins involved in peroxynitrite homeostasis using ROS/RNS conditional proteomics
生成机器学习用于ADAR底物的精准高效RNA编辑	Jiang, Y.	PDF	N/A	Generative machine learning of ADAR substrates for precise and efficient RNA editing
统一采样与排序用于蛋白质对接的DFMDock方法	Chu, L.-S.	PDF	N/A	Unified Sampling and Ranking for Protein Docking with DFMDock
CAMDA 2023：在城市微生物群中寻找模式	Contreras-Peruyero, H.	PDF	N/A	CAMDA 2023: finding patterns in urban microbiomes
ConoDL：一种用于快速生成和预测芋螺毒素的深度学习框架	Guo, M.	PDF	N/A	ConoDL: A Deep Learning Framework for Rapid Generation and Prediction of Conotoxins
通过动力学蒙特卡罗模拟合理化蛋白质-蛋白质相互作用在靶向蛋白质降解中的功能角色	Su, Z.	PDF	N/A	Rationalize the Functional Roles of Protein-Protein Interactions in Targeted Protein Degradation by Kinetic Monte-Carlo Simulations
肿瘤细胞空间组织通过YAP信号传导指导EGFR/RAS/RAF通路主要治疗抵抗	Nakagawa, R.	PDF	N/A	Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling
抑制FOXM1与BCL2抑制剂Venetoclax协同作用，通过抑制MYC通路杀死非t(11;14)多发性骨髓瘤细胞。	Wen, Z.	PDF	N/A	Inhibition of FOXM1 synergizes with BCL2 inhibitor Venetoclax in killing non-t(11;14) multiple myeloma cells via repressing MYC pathway
MKK4和MKK7在青光眼相关损伤后控制视网膜神经节细胞体和轴突的退化。	Marola, O. J.	PDF	N/A	MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury.
ERFVIIs在陆地植物对低氧胁迫响应的进化过程中扮演着氧气感知传感器的角色	Dalle Carbonare, L.	PDF	N/A	The role of ERFVIIs as oxygen-sensing transducers in the evolution of land plant response to hypoxia
小麦NLR蛋白PM3b定位于内质网-质膜接触位点，并通过其LRR结构域与AVRPM3b2/c2相互作用。	Isaksson, J.	PDF	N/A	The wheat NLR protein PM3b localizes to endoplasmic reticulum-plasma membrane contact sites and interacts with AVRPM3b2/c2 through its LRR domain.
植物移动域蛋白-DNA基序模块通过对抗Polycomb沉默来稳定基因表达	Pelissier, T.	PDF	N/A	Plant Mobile Domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression
转录记忆介导硫化物胁迫响应的可塑性，以促进单带海神鳗的适应性	Zhang, W.	PDF	N/A	Transcriptional memories mediate the plasticity of sulfide stress responses to enable acclimation in Urechis unicinctus
一种新型小鼠模型展示了在急性消融成功后中枢神经系统周细胞的在体补充	Atak, D.	PDF	N/A	A Novel Mouse Model Demonstrates In Vivo Replenishment of Central Nervous System Pericytes After Successful Acute Ablation
生长抑素中间神经元选择初始学习阶段背内侧纹状体的表征	Rotariu, S.	PDF	N/A	Somatostatin interneurons select dorsomedial striatal representations of the initial learning phase
HEXIM1与阿尔茨海默病病理相关，并调控神经元中即刻早期基因的动态变化。	Htet, M.	PDF	N/A	HEXIM1 is correlated with Alzheimer's disease pathology and regulates immediate early gene dynamics in neurons
利用吉布斯振铃衰减的T1w/T2w-FLAIR髓鞘MRI绘制皮层特定区域边界图	Autio, J. A.	PDF	N/A	Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI
在患者来源的小鼠模型中，绘制疱疹病毒驱动对卡波西肉瘤细胞微环境和转录组特征的影响	Li, X.	PDF	N/A	Mapping herpesvirus-driven impacts on the cellular milieu and transcriptional profile of Kaposi sarcoma in patient-derived mouse models
跨完整浮游植物开花周期的微生物宏基因组：在22天内每4小时进行一次高分辨率采样	Nunn, B. L.	PDF	N/A	Microbial Metagenomes Across a Complete Phytoplankton Bloom Cycle:High-Resolution Sampling Every 4 Hours Over 22 Days
从朋友到敌人，再回到朋友——共生-对抗连续体中的协同进化转变	Jäger, F.	PDF	N/A	From friend to foe and back - Coevolutionary transitions in the mutualism-antagonism continuum
基因组揭示了禽类吸血蝇（Philornis downsi）在加拉帕戈斯群岛成功入侵的奥秘	Basnet, A.	PDF	N/A	Genomic insights into the successful invasion of the avian vampire fly (Philornis downsi) in the Galapagos Islands
代谢物对人糖酵解异构酶的弱调节作用：一项筛选研究	Jonatansdottir, Y. Y.	PDF	N/A	Weak Modulation of Human Glycolysis Isomerases by Metabolites: A Screening Study
MetaLab平台支持全面的DDA和DIA元蛋白质组学分析	Cheng, K.	PDF	N/A	MetaLab Platform Enables Comprehensive DDA and DIA Metaproteomics Analysis
异二硫化物还原酶A（HdrA）的分子进化与功能分化	Banerjee, M.	PDF	N/A	Molecular Evolution and Functional Divergence of Heterodisulfide Reductase A (HdrA)
酒精对体外原肠胚形成的人类胚胎细胞的转录组、甲基组和代谢组的影响	Wallen, E.	PDF	N/A	Effects of alcohol on the transcriptome, methylome, and metabolome of in vitro gastrulating human embryonic cells
酶促蛋白质融合，产物收率达100%	Fuchs, A. C. D.	PDF	N/A	Enzymatic Protein Fusions with 100% Product Yield
膜蛋白取向排列诱导的囊泡形状变化	Feng, M.	PDF	N/A	Shape transformation of vesicles induced by orientational arrangement of membrane proteins
内在无序蛋白质在其构象集合中可以表现出不同的聚合物行为。	Chakraborty, S.	PDF	N/A	Intrinsically disordered proteins can behave as different polymers across their conformational ensemble
脊髓投射的5-羟色胺能神经元对活跃运动状态的增强作用	Dasen, J.	PDF	N/A	Potentiation of active locomotor state by spinal-projecting serotonergic neurons
在存在内源性无药物脂质纳米颗粒的情况下，mRNA脂质纳米颗粒的结构表征	Chen, X.	PDF	N/A	Structural Characterization of mRNA Lipid Nanoparticles in the Presence of Intrinsic Drug-free Lipid Nanoparticles
一个分层贝叶斯模型揭示了随着内感受训练的进行，传入心脏信号的精确度权重增加，同时焦虑感降低。	Suksasilp, C.	PDF	N/A	A hierarchical Bayesian model reveals increased precision weighting for afferent cardiac signals, and reduced anxiety, as a function of interoceptive training
动作视频游戏玩家的背侧视觉流中的连接性增强	Cahill, K.	PDF	N/A	Connectivity in the Dorsal Visual Stream is Enhanced in Action Video Game Players
Lrrk2和Snca缺陷变异不会改变新生小鼠因神经亲嗜性呼肠孤病毒T3D引起的原发性脑炎的病程。	Lunn, M. O.	PDF	N/A	Variants in Lrrk2 and Snca deficiency do not alter the course of primary encephalitis due to neurotropic reovirus T3D in newborn mice
桥联脂质转移蛋白3A（BLTP3A）与晚期内吞途径的膜相关，并作为CASM的效应器。	Hanna, M. G.	PDF	N/A	Bridge-like lipid transfer protein 3A (BLTP3A) is associated with membranes of the late endocytic pathway and is an effector of CASM
我们能从遗留物中发现什么：半水生昆虫蜕皮的DNA代谢条形码研究	Dworatzek, S.	PDF	N/A	What we can find in what's left behind: DNA metabarcoding of semi-aquatic insect exuviae
tRNA池的进化塑造了Saccharomycotina亚门中密码子使用选择的变化	Cope, A. L.	PDF	N/A	Evolution of tRNA pool shapes variation in selection on codon usage across the Saccharomycotina subphylu
通过X染色体筛选和基因编辑获得的Ogden综合征（NAA10）和NAA15患者来源的诱导多能干细胞系及其同源配对库。	Wesely, J.	PDF	N/A	A repository of Ogden syndrome (NAA10) and NAA15 patient derived iPSC lines and isogenic pairs by X-chromosome screening and genome-editing.
选择促进线粒体基因组的年龄依赖性退化	Korotkevich, E.	PDF	N/A	Selection promotes age-dependent degeneration of the mitochondrial genome
量化影响拟南芥基因RNA二级结构的SNP的进化	Martin, G. T.	PDF	N/A	Quantifying evolution of SNPs that affect RNA secondary structure in Arabidopsis thaliana genes
一种经过计算设计的多样且选择性强的过氧化酶面板，用于萜类化合物的氧功能化	Munch, J.	PDF	N/A	A computationally designed panel of diverse and selective peroxygenases for terpene oxyfunctionalization
少即是多：慢密码子窗口增强eGFP mRNA对RNA干扰的抵抗力	Mueller, J. A.	PDF	N/A	Less is more: Slow-codon windows enhance eGFP mRNA resilience against RNA interference
时间分辨的单个葡萄果实转录组：膜运输作为双S型生长的开关	Savoi, S.	PDF	N/A	Time-resolved transcriptomic of single V. vinifera fruits: membrane transports as switches of the double sigmoidal growth
MirGeneDB 3.0：改进的分类学采样，统一命名新发现的保守微RNA家族，以及更新的协方差模型。	Clarke, A. W.	PDF	N/A	MirGeneDB 3.0: Improved taxonomic sampling, uniform nomenclature of novel conserved microRNA families, and updated covariance models.
irCLIP-RNP和Re-CLIP揭示了RNA上动态蛋白质关联的模式	DUCOLI, L.	PDF	N/A	irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA
人类线粒体ClpP蛋白酶的变构激活机制	Goncalves, M. M.	PDF	N/A	Mechanism of allosteric activation in human mitochondrial ClpP protease
一种用于胞内检测丙二酰辅酶A的基因编码荧光生物传感器	Ranzau, B. L.	PDF	N/A	A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA
酶活性通过调节拥挤环境中的粘度来调控底物扩散	Bevilacqua, A.	PDF	N/A	Enzyme Activity Regulates Substrate Diffusion by Modulating Viscosity in Crowded Milieu
溶血磷脂酰基团大小、酰基链长度及饱和度对液泡酸化、Ca²⁺转运及融合具有不同的影响。	Zhang, C.	PDF	N/A	Lysophospholipid headgroup size, and acyl chain length and saturation differentially affect vacuole acidification, Ca2+ transport, and fusion
Tris通过线性混合抑制机制抑制GH1 β-葡萄糖苷酶。	Chagas, R. S.	PDF	N/A	Tris inhibits a GH1 β-glucosidase by a linear mixed inhibition mechanism
利用工程化受体实现合成mRNA的胞外配体响应性翻译调控	Nakanishi, H.	PDF	N/A	Extracellular ligand-responsive translational regulation of synthetic mRNAs using engineered receptors
novoStoic2.0：一个综合框架，用于路径合成、热力学评估和酶选择	Upadhyay, V.	PDF	N/A	novoStoic2.0: An integrated framework for pathway synthesis, thermodynamic evaluation, and enzyme selection
PEG调整使利用丝状支原体受体进行基因组移植成为可能	Karas, B. J.	PDF	N/A	PEG Adjustment Enables Genome Transplantation Using Mycoplasma Mycoides Recipient
AAV血清型转导嗅觉感觉神经元的比较分析	Belfort, B. D.	PDF	N/A	Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons
一种双调蛋白报告基因小鼠能够实现修复性肺部调节性T细胞的转录和克隆扩增分析。	Loffredo, L. F.	PDF	N/A	An amphiregulin reporter mouse enables transcriptional and clonal expansion analysis of reparative lung Treg cells
米诺环素增强了未极化巨噬细胞对鲍曼不动杆菌的抗菌活性，同时减少了炎症反应。	Guerra, A. D.	PDF	N/A	Minocycline enhances antimicrobial activity of unpolarized macrophages against Acinetobacter baumannii while reducing the inflammatory response
克罗恩病最早的病变——口腔溃疡的转录组学特征表明，细菌侵袭性挑战而非整体菌群失调是引发因素。	Whiley, P. J.	PDF	N/A	Transcriptomic signatures of host immune responses in aphthous ulcers, the earliest lesions of Crohn's disease, suggest that a bacterial invasive challenge, rather than global dysbiosis, is the initiating factor.
基因组导向研究揭示了一组磷脂酶，并突显了沙门氏菌T6SS效应蛋白的多样性。	Nicastro, G. G.	PDF	N/A	Genome-directed study uncovers a family of phospholipases and highlights the diversity of Salmonella T6SS effectors.
Tailocin介导的软腐病欧氏杆菌属细菌间的相互作用	Borowicz, M.	PDF	N/A	Tailocin-mediated interactions in Soft Rot Pectobacteriaceae
弓形虫速殖子和缓殖子中的运动依赖性过程：相同却又不同	Kent, R. S.	PDF	N/A	Motility-dependent processes in Toxoplasma gondii tachyzoites and bradyzoites: same same but different
通过深度测序结合平衡核苷酸合成内参法，对低生物量样本抗生素处理后16S基因拷贝进行精确定量	Chang, C.-C.	PDF	N/A	Accurate quantitation of 16S gene copies in low biomass samples post-antibiotic treatment through deep sequencing with a balanced nucleotide synthetic spike-in approach
Ing4缺失增强了多能祖细胞中的造血再生	Anderson, G. A.	PDF	N/A	Loss of Ing4 enhances hematopoietic regeneration in multipotent progenitor cells
斑马鱼Pol-Theta和人Pol-Theta，具有同源功能的直系同源物	Thomas, C.	PDF	N/A	Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function
由CRISPR-Cas9 DNA双链断裂引发的兆碱基级杂合性缺失	Regan, S. B.	PDF	N/A	Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks
强效且选择性的SETDB1共价负变构调节剂可降低细胞中的甲基转移酶活性	Uguen, M.	PDF	N/A	Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells
AAV9介导的针对天然反义转录本的靶向治疗作为一种新型治疗手段用于Dravet综合征	Antinao Diaz, J. F.	PDF	N/A	AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome
外膜变化使细菌能够逃避捕食者的进化	Mridha, S.	PDF	N/A	Outer membrane changes enable evolutionary escape from bacterial predation
鉴定药物/代谢物转运蛋白1作为NF54xCam3.II恶性疟原虫遗传杂交中奎宁抗性的标志物。	Kanai, M.	PDF	N/A	Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54xCam3.II P. falciparum genetic cross.
早期内体逃逸可提高所递送酶类货物的催化活性	Vazquez Maldonado, A. L.	PDF	N/A	Earlier endosomal escape improves the catalytic activity of delivered enzyme cargo
通过在水相中使用角质酶或脂肪酶，实现含有酯键的氧化聚乙烯的高效降解	Kong, D.	PDF	N/A	Efficient degradation of oxidized polyethylene containing ester bonds by cutinase or lipase in aqueous phase
DNA聚合酶Zeta是一种强健的逆转录酶。	Mayle, R.	PDF	N/A	DNA polymerase Zeta is a robust reverse transcriptase
建模锥虫运动	Overberg, F. A.	PDF	N/A	Modelling trypanosome motility
秀丽隐杆线虫体细胞中核Argonaute蛋白HRDE-1和NRDE-3的独特调控机制。	Mendoza, H.	PDF	N/A	Distinct regulatory mechanisms by the nuclear Argonautes HRDE-1 and NRDE-3 in the soma of Caenorhabditis elegans.
2型糖尿病和肥胖症中增加的骨炎症与Wnt信号下调和骨强度降低相关	Leanza, G.	PDF	N/A	Increased bone inflammation in type 2 diabetes and obesity correlates with Wnt signaling downregulation and reduced bone strength
深度学习有助于植物抗病基因的精准鉴定	Liu, Z.	PDF	N/A	Deep learning facilitates precise identification of disease-resistance genes in plants
在自然阅读过程中，对正字法和语义旁中央凹信息的快速层次处理	Wang, L.	PDF	N/A	Fast hierarchical processing of orthographic and semantic parafoveal information during natural reading
AIM2对HNSCC发展的影响	Reinartz, D. M.	PDF	N/A	Impact of AIM2 on HNSCC Development
PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection	Williams, D. E.	PDF	N/A	PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection
军团菌自诱导物LAI-1的跨界信号传递涉及抗微生物鸟苷酸结合蛋白GBP。	Solger, F.	PDF	N/A	Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP
鉴定和表征链球菌性猪病完全毒力所需的ugpE基因	Yang, Q.	PDF	N/A	Identification and characterization of ugpE required for the full virulence of Streptococcus suis
在易患坏死性小肠结肠炎期间，对产后小肠转录组进行编目	Oliveria, L. F. S.	PDF	N/A	Cataloguing the postnatal small intestinal transcriptome during the period of susceptibility to necrotizing enterocolitis
嗜热菌G. icigianus细胞对太赫兹辐射的转录组响应	Bryanskaya, A.	PDF	N/A	The transcriptomic response of cells of the thermophilic bacterium G. icigianus to THz irradiation
社交孤立压力对基于空间学习任务中涉及热威胁的安全学习和防御行为结构的影响	Villalon, S. A.	PDF	N/A	Impact of social isolation stress on safety learning and the structure of defensive behavior during a spatial-based learning task involving thermal threat
# BioRxiv 2024-09-27 Papers

标题	作者	PDF链接	代码仓库	Title
V1中的离散化表示预测了次优的方向辨别能力	Corbo, J.	PDF	N/A	Discretized representations in V1 predictsuboptimal orientation discrimination
不同训练方案下小鼠白色和棕色脂肪组织自噬变化的差异	Tamargo-Gomez, I.	PDF	N/A	Autophagy alterations in white and brown adipose tissues of mice exercised under different training protocols
不同的抑制性神经元以不同的方式塑造听觉皮层中声音强度的神经编码	Tobin, M.	PDF	N/A	Distinct inhibitory neurons differently shape neuronal codes for sound intensity in the auditory cortex
淀粉样β单体扩散性对老年斑形成的影响	Kuznetsov, A. V.	PDF	N/A	Effect of diffusivity of amyloid beta monomers on the formation of senile plaques
Syngap1通过调节皮层感觉运动动力学促进认知功能	Vaissiere, T.	PDF	N/A	Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics
通过干预措施使生存曲线变陡，从而压缩发病率	Yang, Y.	PDF	N/A	Compression of morbidity by interventions that steepen the survival curve
可预测的顺序结构增强了听觉在阈值处的敏感性。	Marin, N.	PDF	N/A	Predictable sequential structure augments auditory sensitivity at threshold
可预测性和个体阿尔法频率如何塑造记忆：来自事件相关电位研究的启示	Jano, S. L.	PDF	N/A	How predictability and individual alpha frequency shape memory: insights from an event-related potential investigation
物种内花的进化揭示了在初始传粉者转变过程中适应性行走的趋同现象	Wenzell, K. E.	PDF	N/A	Within-species floral evolution reveals convergence in adaptive walks during incipient pollinator shift
单细胞多组学和空间图谱揭示了B细胞淋巴瘤的肿瘤内异质性由分化驱动	Fitzgerald, D.	PDF	N/A	A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity
在群体放电中分离神经振荡的单个周期	Sabri, E.	PDF	N/A	Isolating Single Cycles of Neural Oscillations in Population Spiking
蓝斑核对前额叶动态的调节及对灵活规则切换的编码	Nigro, M.	PDF	N/A	Locus coeruleus modulation of prefrontal dynamics and encoding of flexible rule switching
使用新型空间DNA芯片对小鼠肝脏进行2微米分辨率的空间转录组测序	Ding, X.	PDF	N/A	Spatial Transcriptomics Sequencing of Mouse Liver at 2 Micron Resolution Using a Novel Spatial DNA Chip
全氟和多氟烷基物质在分化神经细胞中的转录组效应	Running, L.	PDF	N/A	Transcriptomics effects of per- and polyfluorinated alkyl substances in differentiated neuronal cells
周期蛋白依赖性激酶5（Cdk5）的活性受光调节，并调控昼夜节律钟的快速相位转变。	Brenna, A.	PDF	N/A	Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock
一种用于调控哺乳动物细胞命运的温度诱导蛋白模块	Benman, W.	PDF	N/A	A temperature-inducible protein module for control of mammalian cell fate
功能性磁共振成像数据集上的伸缩式独立成分分析	Mirzaeian, S.	PDF	N/A	A Telescopic Independent Component Analysis on Functional Magnetic Resonance Imaging Data Set
揭示白细胞介素-12药代动力学脱敏机制及其后果的数学建模研究	DeBonis, J.	PDF	N/A	Uncovering the Interleukin-12 Pharmacokinetic Desensitization Mechanism and Its Consequences with Mathematical Modeling
在递归网络中将神经流形与电路结构相连接	Pezon, L.	PDF	N/A	Linking Neural Manifolds to Circuit Structure in Recurrent Networks
长读长测序与自然历史收藏样本及复杂样本的基因组组装	Bein, B.	PDF	N/A	Long-read sequencing and genome assembly of natural history collection samples and challenging specimens
T细胞极化和NFAT易位依赖于硬度，并且受到Piezo1和Orai1的不同调控。	Zhao, R.	PDF	N/A	T cell polarization and NFAT translocation are stiffness-dependent and are differentially regulated by Piezo1 and Orai1
利用生理状况标记揭示自然啮齿动物种群中轻度干旱条件的负面影响	Keilani, H. S.	PDF	N/A	Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura
蛋白质进化中上位性的突发时间尺度	Di Bari, L.	PDF	N/A	Emergent time scales of epistasis in protein evolution
B细胞α(v)整合素调控流感病毒感染后生发中心来源的肺驻留IgA B细胞反应	Montiel-Armendariz, A.	PDF	N/A	B cell alpha(v) integrin regulates germinal center derived lung-resident IgA B cell responses following influenza virus infection
为了改进全长核糖体密度预测，通过连接序列和基于图的表示方法	Nallapareddy, M. V.	PDF	N/A	Towards improving full-length ribosome density prediction by bridging sequence and graph-based representations
蜘蛛社会性的基因组后果及持久性	Ma, J.	PDF	N/A	The genomic consequences and persistence of sociality in spiders
肾近端小管细胞特异性Megalin缺失不影响小鼠高脂饮食诱导的动脉粥样硬化，但可诱发小管间质性肾炎	Amioka, N.	PDF	N/A	Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet
肾近端小管细胞特异性Megalin缺失不影响小鼠高脂饮食诱导的动脉粥样硬化，但可诱发小管间质性肾炎	Amioka, N.	PDF	N/A	Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet
结合物理与药物的骨质疏松症治疗方案能够协同增强骨骼反应及局部力学调控	Schulte, F. A.	PDF	N/A	Combined physical and pharmaceutical anabolic osteoporosis therapies synergistically increase bone response and local mechanoregulation
通过Shielded DNA-PAINT标记协议减少超分辨率DNA-PAINT标记的非特异性结合	Lucinskaite, E.	PDF	N/A	Reduced non-specific binding of super-resolution DNA-PAINT markers by Shielded DNA-PAINT labeling protocols
一系列增强型AAV和转基因小鼠品系，用于遗传访问皮质细胞类型	Ben-Simon, Y.	PDF	N/A	A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types
生物医学文献中的生活方式因素：本体论与全面的命名实体识别资源	Nourani, E.	PDF	N/A	Lifestyle factors in the biomedical literature: An ontology and comprehensive resources for named entity recognition
在休息和手臂运动期间，猕猴的辅助运动区和初级运动皮层的微观钙成像	Martel, A.-C.	PDF	N/A	MICROENDOSCOPIC CALCIUM IMAGING IN SUPPLEMENTARY MOTOR AREA AND PRIMARY MOTOR CORTEX OF RHESUS MACAQUES AT REST AND DURING ARM MOVEMENT
相同特征，不同基因：阿尔伯塔省三个溪流刺鱼群体的盆骨脊椎缺失	Mee, J. A.	PDF	N/A	Same trait, different genes: pelvic spine loss in three brook stickleback populations in Alberta
急性全身照射对胸腺上皮细胞的第二次影响	Namiki, K.	PDF	N/A	Second impact of an acute total body irradiation on thymic epithelial cells
利用OptFed优化生物加工效率：动态非线性建模提升产品与生物量产率	Schloegel, G.	PDF	N/A	Optimizing Bioprocessing Efficiency with OptFed: Dynamic Nonlinear Modeling Improves Product-to-Biomass Yield
基于纳米孔的分析揭示了科特迪瓦、坦桑尼亚、乌干达和老挝人类感染的鞭虫物种的遗传景观和系统发育位置。	Rahman, N.	PDF	N/A	Nanopore-based analysis unravels the genetic landscape and phylogenetic placement of human-infecting Trichuris species in Cote d'Ivoire, Tanzania, Uganda, and Laos
氯氰菊酯在小丑鱼变态过程中产生的多层次影响	Reynaud, M.	PDF	N/A	The multi-level effect of chlorpyrifos during clownfish metamorphosis
鞘氨醇-1-磷酸信号调节穆勒胶质细胞转变为具有神经发生能力、增殖性前体样细胞的能力	Taylor, O.	PDF	N/A	Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells
PTEN的neddylation加剧了乳腺癌中CDK4/6抑制剂的耐药性	Liu, F.	PDF	N/A	PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
联会复合体通过湿润作用使减数分裂染色体排列。	Gordon, S.	PDF	N/A	The synaptonemal complex aligns meiotic chromosomes by wetting
同时对选择和信心程度的深思熟虑的神经基础	Vivar-Lazo, M.	PDF	N/A	Neural basis of concurrent deliberation toward a choice and degree of confidence
工作记忆处理增强了长期记忆的神经表征	Sabo, M.	PDF	N/A	Working memory processing boosts the neural representation of long-term memories
乙醇培养下耶氏酵母的生理定量与生物量组成	Vieira-Lara, M. A.	PDF	N/A	Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures
具身视角：角回和楔前叶在自然事件记忆中解码自我身份	Iriye, H.	PDF	N/A	An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events
Ki-67和CDK1调控核脂质与有丝分裂染色体的动态结合	Hu, H.-T.	PDF	N/A	Ki-67 and CDK1 Control the Dynamic Association of Nuclear Lipids with Mitotic Chromosomes
人类重复SRGAP2的斑马鱼模型揭示了其在小胶质细胞和视觉系统发育中的新功能	Uribe-Salazar, J. M.	PDF	N/A	Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development
利用直接胶原纤维模型捕捉巩膜各向异性。将微观结构与宏观力学性能联系起来。	Ji, F.	PDF	N/A	Capturing sclera anisotropy using direct collagen fiber models. Linking microstructure to macroscopic mechanical properties.
BirdNET在欧洲城市进行鸟类声学监测方面与专家一样出色。	Fairbairn, A. J.	PDF	N/A	BirdNET is as good as experts for acoustic bird monitoring in a European city
在青蛙变态发育过程中，脊髓神经元的多样性随着从游泳到四肢运动的转变呈指数级增长。	Vijatovic, D.	PDF	N/A	Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis
气道应用的IVT mRNA疫苗需要特定的序列设计和高标准的纯化，以去除具有破坏性的双链RNA污染物。	Zhang, J.	PDF	N/A	Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminant
利用动态核极化增强的固态核磁共振技术对天然细菌生物膜进行高灵敏度分析	Byeon, C.-H.	PDF	N/A	High-Sensitivity Analysis of Native Bacterial Biofilms Using Dynamic Nuclear Polarization-Enhanced Solid-State NMR
平衡生长：GROOT基因在拟南芥中连接植物生物量与温度适应性	Razzaque, S.	PDF	N/A	Balancing Growth: GROOT Genes Link Plant Biomass and Temperature Adaptation in Arabidopsis
将工程化的人类ARMMs作为治疗性非病毒载体用于体内递送基因编辑有效载荷	Wang, Q.	PDF	N/A	Engineering Human ARMMs as Therapeutic Non-Viral Vehicles for in vivo Delivery of Genome Editing Payloads
LOCAS：基于监督对比学习的mRNA多标签定位	Abir, A. R.	PDF	N/A	LOCAS: Multi-label mRNA Localization with Supervised Contrastive Learning
酶法合成稀有的ΔUA（1->4）Glc 3, 6, N-硫酸化肝素二糖，对肝素质量控制的意义	Kandola, T. K.	PDF	N/A	Enzymatic access to the rare ΔUA (1->4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control
翻译结果：

转化性慢性变量应激程序中的样本量报告与合理性：一项系统性综述 | Jordan, C. | PDF | N/A | Reporting and justification of sample size in translational chronic variable stress procedures: A systematic review | | 慢性β淀粉样蛋白寡聚体注射入海马后神经元活动和神经递质释放同时评估的协议 | Herve, V. | PDF | N/A | Protocol for simultaneous evaluation of neuronal activity and neurotransmitter release following chronic amyloid-beta oligomer injections into the hippocampus | | 新生儿缺氧缺血性脑病的鼻内治疗：系统综述、综合分析及对全球护理可及性的影响 | Cavanagh, A. S. | PDF | N/A | Intranasal therapies for neonatal hypoxic-ischemic encephalopathy: Systematic review, synthesis, and implications for global accessibility to care | | 消除常见的神经选择信号并不会使它们成为人工产物。对Frömer等人（2024，《自然·人类行为》）的评论。 | O'Connell, R. G. | PDF | N/A | Regressing Away Common Neural Choice Signals does not make them Artifacts. Comment on Frömer et al (2024, Nature Human Behaviour) | | 消除常见的神经选择信号并不会使它们成为人工产物。对Frömer等人（2024年，《自然·人类行为》）的评论。 | O'Connell, R. G. | PDF | N/A | Regressing Away Common Neural Choice Signals does not make them Artifacts. Comment on Frömer et al (2024, Nature Human Behaviour) | | p97-UBXD8复合体通过抑制过氧化物酶体自噬来维持过氧化物酶体的丰度。 | Montes, I. D. | PDF | N/A | The p97-UBXD8 complex maintains peroxisome abundance by suppressing pexophagy | | 阿维巴坦广谱直接抗菌活性的耐药性迅速出现 | Nägeli, M. | PDF | N/A | Rapid Emergence of Resistance to Broad-Spectrum Direct Antimicrobial Activity of Avibactam | | 菲氏家族成员协同调控军团菌肺炎的毒力 | Andrea, C. | PDF | N/A | Fis family members synergistically control the virulence of Legionella pneumophila | | 全基因组甲基化测序在轻度认知障碍和阿尔茨海默病所致痴呆患者的血液样本中识别认知状态 | Madrid, A. | PDF | N/A | Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer's disease identifies cognitive status | | HuBMAPR：一个用于HuBMAP数据门户的R客户端 | Hou, C. | PDF | N/A | HuBMAPR: an R Client for the HuBMAP Data Portal | | 用于评估癌症进展和患者病程的组合随机模型 | Wieland, V. | PDF | N/A | Combined Stochastic Models for the Evaluation of Cancer Progression and Patient Trajectories | | 一种通过深度卷积神经网络进行特征选择以编码非线性功能网络连接性的方法及其在精神障碍分类中的应用 | Vo, D. M. | PDF | N/A | A Method of Feature Selection via Deep Convolution Neural Networks For Encoding Nonlinear Functional Network Connectivity and Its Application To The Classification of Mental Disorders | | 创新性的血小板来源外泌体药物递送系统用于治疗角膜新生血管 | Liu, G.-S. | PDF | N/A | Innovative platelet-derived extracellular vesicle drug delivery system for the treatment of corneal neovascularization | | WIMOAD：阿尔茨海默病（AD）诊断的多组学数据加权整合 | Xiao, H. | PDF | N/A | WIMOAD: Weighted Integration of Multi-omics data for Alzheimer's Disease (AD) Diagnosis | | 利用拉曼光谱探索循环外泌体中与乳腺癌相关的生化变化 | Bonizzi, A. | PDF | N/A | Exploring Breast Cancer-Related Biochemical Changes in Circulating Extracellular Vesicles Using Raman Spectroscopy | | 伊米普利酮ONC201或ONC206与替莫唑胺及放疗的三重ITR疗法联合应用，可降低原位野生型IDH胶质母细胞瘤小鼠模型的颅内肿瘤负荷并延长生存期。 | Zhou, L. | PDF | N/A | Combination of Imipridone ONC201 or ONC206 with Temozolomide and Radiotherapy in triple ITR therapy reduces intracranial tumor burden and prolongs survival in an orthotopic wild-type IDH GBM mouse model | | 肿瘤相关巨噬细胞重编程的免疫景观 | Duval, F. | PDF | N/A | The Immune Landscape of Tumor-Associated Macrophage Reprogramming | | 单细胞元分析揭示了T细胞对检查点免疫疗法反应的克隆动力学 | Shorer, O. | PDF | N/A | Single-cell meta-analysis of T cells reveals clonal dynamics of response to checkpoint immunotherapy | | 在部分肌肉去激活期间进行束状伸展，并不会增强人类胫骨前肌随后的神经肌肉输出。 | Raiteri, B. J. | PDF | N/A | Fascicle stretch during partial muscle deactivation does not enhance the human tibialis anterior's subsequent neuromechanical output | | 对全球羽扇豆遗传资源进行遗传和表型特征分析，以开发核心收集品 | Tanwar, U. K. | PDF | N/A | Genetic and phenotypic characterization of global Lupinus albus genetic resources for the development of a CORE collection | | 测定达尔林-锡金喜马拉雅地区特有的多倍体辣椒品种Dalle Khursani中的辣椒素含量及辣度水平 | Ghimiray, T. S. | PDF | N/A | Determination of Capsaicin content and pungency levels in Dalle Khursani accessions, a polyploid Capsicum species specific to Darjeeling-Sikkim Himalaya, India | | 精神分裂症中的自发脑活动与突触密度：一项结合UCB-J PET和fMRI的研究 | Shatalina, E. | PDF | N/A | Spontaneous brain activity and synaptic density in schizophrenia: a combined UCB-J PET and fMRI study | | 健康人体认知功能期间脑激活与线粒体复合物I蛋白水平之间的关系：一项基于BCPP-EF PET和功能性MRI的任务切换研究 | Shatalina, E. | PDF | N/A | The relationship between brain activation and mitochondrial complex I protein levels during cognitive function in healthy humans: an BCPP-EF PET and functional MRI study of task switching | | 竞争下的进化通过减少净能量通量和生长的密度依赖性来增加浮游植物的生产力。 | Briddon, C. L. | PDF | N/A | Evolution under competition increases phytoplankton production by reducing the density-dependence of net energy fluxes and growth | | 用于约会并具有置信度的混合模型 | Darlim, G. | PDF | N/A | Mixture Models for Dating with Confidence | | 独特的可及性与选择性相互作用塑造了结直肠癌腹膜转移的发展过程 | Wassenaar, E. C. | PDF | N/A | A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer | | 基于表达的选择鉴定出一种对小胶质细胞具有亲和力的AAV衣壳，适用于小鼠的直接和脑脊液途径给药 | Maguire, C. | PDF | N/A | Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice | | 斑马鱼的多行为表型分析揭示了一种新型非联想学习干扰因子，具有环境和人类相关性 | Leuthold, D. | PDF | N/A | Multi-behavioral phenotyping in zebrafish identifies a novel disruptor of non-associative learning with environmental and human relevance | | 线粒体orf125影响马铃薯（+）S. commersonii体细胞杂交的雄性生育力，并参与“Tuberosum”型细胞质雄性不育的启动及普通马铃薯的进化。 | Tamburino, R. | PDF | N/A | The mitochondrial orf125 affects male fertility of Solanum tuberosum (+) S. commersonii somatic hybrids and participates in the onset of ''Tuberosum''-Type CMS and evolution of common potato | | CCR5拮抗剂作为神经保护和增强中风恢复的药物：一项临床前系统综述和荟萃分析 | Sharif, A. | PDF | N/A | CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis | | 使用静息状态功能性磁共振成像的因果关系映射揭示了精神分裂症患者的高活动性和低连接性 | Tahir, A. | PDF | N/A | Causality Mapping Using Resting-state fMRI Reveals Hyperactivity and Hypoconnectivity in Schizophrenia Patients | | 预测气候变化下雌雄异株植物物种的分布范围变化 | Moutouama, J. K. | PDF | N/A | Forecasting range shifts of a dioecious plant species under climate change | | 三维摄影测量作为一种低成本、便携且非侵入性的方法，用于听觉声学建模。 | Vesterholm, K. K. | PDF | N/A | 3D photogrammetry as a low cost, portable and noninvasive method for acoustic modeling of hearing | | 体外工程化稳定siRNA脂质纳米颗粒：探索可电离脂质浓度对增强制剂稳定性的影响 | Biswal, M. R. | PDF | N/A | In Silico Engineering of Stable siRNA Lipid Nanoparticles: Exploring the Impact of Ionizable Lipid Concentrations for Enhanced Formulation Stability | | TbRGG2 RRM中结合位点灵活性促进RNA扫描的分子动力学模拟研究 | Lemmens, T. | PDF | N/A | How Binding Site Flexibility Promotes RNA Scanning in TbRGG2 RRM: A Molecular Dynamics Simulation Study | | 重复低强度聚焦超声在TgF344-AD大鼠中长期导致小胶质细胞谱系变化 | Abjean, L. | PDF | N/A | Repeated low-intensity focused ultrasound led to microglial profile changes at long term in TgF344-AD rats | | CLYBL通过消除丙二酰辅酶A，避免了甲基丙二酰辅酶A变位酶的抑制和维生素B12的损失。 | Griffith, C. M. | PDF | N/A | CLYBL averts methylmalonyl-CoA mutase inhibition and loss of vitamin B12 by eliminating malyl-CoA | | PfSir2A的生化特性及抑制剂发现——老酶新用 | Donu, D. | PDF | N/A | Biochemical Characterization and Inhibitor Discovery for PfSir2A -- New Tricks for An Old Enzyme | | 丙烯酸改性聚乙二醇微粒用于神经应用中胰岛素样生长因子-1的亲和释放 | Ramos Ferrer, P. | PDF | N/A | Acrylic Acid Modified Poly-ethylene Glycol Microparticles for Affinity-Based release of Insulin-Like Growth Factor-1 in Neural Applications | | AnalyzAIRR：一个用户友好的指导性工作流程，用于AIRR数据分析 | Mhanna, V. | PDF | N/A | AnalyzAIRR: A user-friendly guided workflow for AIRR data analysis | | 可调椭圆柱体用于单DNA分子旋转力学研究 | Hong, Y. | PDF | N/A | Tunable Elliptical Cylinders for Rotational Mechanical Studies of Single DNA Molecules | | 靶向耐药黑色素瘤中异常真核翻译起始因子4E（eIF4E）活性的第二代Cap类似物前药 | Cardenas, E. L. | PDF | N/A | Second-Generation Cap Analogue Prodrugs for Targeting Aberrant Eukaryotic Translation Initiation Factor 4E (eIF4E) Activity in Drug-Resistant Melanoma | | 早晨激活肝胰岛素受体可改善下午的肝糖处理和储存 | Waterman, H. L. | PDF | N/A | Morning Engagement of Hepatic Insulin Receptors Improves Afternoon Hepatic Glucose Disposal and Storage | | 利用快速眼动睡眠期间的靶向记忆再激活来解除情感记忆 | Greco, V. | PDF | N/A | Disarming emotional memories using Targeted Memory Reactivation during Rapid Eye Movement sleep | | 孤立皮层网络中的时间信息编码 | Ferdous, Z. I. | PDF | N/A | Temporal Information Encoding in Isolated Cortical Networks | | 用于光刺激和电生理记录的铸造双色纳米光子神经探针 | Roszko, D. A. | PDF | N/A | Foundry-fabricated dual-color nanophotonic neural probes for photostimulation and electrophysiological recording | | 通过质谱法对衰老小鼠大脑进行多平台脂质分析 | Panda, P. | PDF | N/A | Multiplatform lipid analysis of the brain of aging mice by mass spectrometry | | 持续注意状态的振荡动力学 | Solis-Vivanco, R. | PDF | N/A | Oscillatory dynamics of sustained attention states | | 用于在脑脊液中检测亨廷顿蛋白的挑战与进展：支持相对定量 | Harding, R. J. | PDF | N/A | Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification | | 斑马鱼后连合核中视觉运动和地标位置的表征与航向方向一致。 | Lavian, H. | PDF | N/A | The representation of visual motion and landmark position aligns with heading direction in the zebrafish interpeduncular nucleus | | 通过突触蛋白消除的负反馈维持突触可塑性：KIBRA-PKMζ相互作用在长时程增强和记忆中的动态建模 | Shouval, H. | PDF | N/A | Maintenance of synaptic plasticity by negative-feedback of synaptic protein elimination: Dynamic modeling of KIBRA-PKMζ interactions in LTP and memory | | 疟原虫查氏感染后造血干细胞群体的不同反应及恢复动力学。 | Bruno, F. | PDF | N/A | Differential responses and recovery dynamics of HSPC populations following Plasmodium chabaudi infection. | | 巨杉的水分利用效率在山坡生境中高于河岸生境 | Liu, M. | PDF | N/A | Water use efficiency of Cupressus gigantea is higher in mountain slope habitats compared to riverside habitats | | 检测从“狗衰老项目”参与者处收集的饮用水中的重金属含量 | Sexton, C. | PDF | N/A | Testing for heavy metals in drinking water collected from Dog Aging Project participants | | 生态动力学解释了海洋中的模块化反硝化作用 | Sun, X. | PDF | N/A | Ecological dynamics explain modular denitrification in the ocean | | 探索基于环境-代理模型的五大湖管嘴鹬风险评估方法 | Edwards, B. P. | PDF | N/A | Exploring the use of environment-agent-based models for risk assessment of Great Lakes piping plovers | | 滑坡效应：通过气候避难所的视角评估两栖动物灭绝危机 | Andersen, D. K. | PDF | N/A | A slippery slope: assessing the amphibian extinction crisis through the lens of climate refugia | | 博物馆分析揭示了南极冰鱼物种的多样性。 | Garmann-Aarhus, B. | PDF | N/A | Museomics analyses inform about Channichthys icefish species diversity | | 使用基于R的地理信息系统工具定义环境宏基因组学研究的目标人群 | Cruz, D. D. | PDF | N/A | Defining Target Population of Environments to Enviromics Studies Using R-based GIS Tools | | 野化改变小鼠的表观遗传衰老 | Zipple, M. N. | PDF | N/A | Rewilding alters mouse epigenetic aging | | 用于筛选异构化介导酶药物靶点的差分离子迁移声波喷射质谱系统 | bazargan, s. | PDF | N/A | A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets | | 工程化活体材料中有序释放微生物 | Kalairaj, M. S. | PDF | N/A | Controlled release of microorganisms from engineered living materials | | 森林中的骷髅：在贝叶斯系统发育树分布上使用基于熵的恶意检测 | Klawitter, J. | PDF | N/A | Skeletons in the Forest: Using Entropy-Based Rogue Detection on Bayesian Phylogenetic Tree Distributions | | 区间删失对生物高通量筛选中数据准确性和机器学习性能的影响 | Doffini, V. | PDF | N/A | Impact of Interval Censoring on Data Accuracy and Machine Learning Performance in Biological High-Throughput Screening | | 利用细胞类型特异性进行单细胞转录组基因集分析 | Frost, H. R. | PDF | N/A | Leveraging cell type-specificity for gene set analysis of single cell transcriptomics | | TMEM16蛋白的稳健脂质翻转需要开放的沟槽和薄膜 | Stephens, C. A. | PDF | N/A | Robust lipid scrambling by TMEM16 proteins requires an open groove and thin membrane | | 亲脂性分子转子用于评估纳米乳液液滴中油核的粘度 | Elhassan, M. | PDF | N/A | Lipophilic molecular rotor to assess the viscosity of oil core in nano-emulsion droplets | | 一种基因编码的荧光传感器能够实现对IDH突变相关肿瘤代谢物D-2-羟基戊二酸的灵敏和特异性检测。 | Choate, K. A. | PDF | N/A | A genetically encoded fluorescent sensor enables sensitive and specific detection of IDH mutant associated oncometabolite D-2-hydroxyglutarate | | Trem2缺乏会减弱瘦小鼠的乳腺癌肿瘤生长，但对肥胖或体重减轻的小鼠则无此效果，并且与克隆T细胞群体的改变相关。 | Pierro, E. W. | PDF | N/A | Trem2 deficiency attenuates breast cancer tumor growth in lean, but not obese or weight loss, mice and is associated with alterations of clonal T cell populations | | 多模态空间分析揭示了输卵管高级别浆液性卵巢癌前体中的免疫抑制和微环境重塑 | Kader, T. | PDF | N/A | Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma | | 体细胞线粒体DNA突变负荷塑造白血病发生中的代谢可塑性 | Li-Harms, X. | PDF | N/A | Somatic mtDNA Mutation Burden Shapes Metabolic Plasticity in Leukemogenesis | | 妊娠期砷暴露改变了母体产后心脏大小，并诱导心肌细胞钙处理失调 | Taube, N. | PDF | N/A | Gestational arsenite exposure alters maternal postpartum heart size and induces Ca2+ handling dysregulation in cardiomyocytes | | 阐明多重反馈回路在调节干细胞决策中的作用 | Shaikh, R. | PDF | N/A | Elucidating the role of multiple feedback loops in regulating stem cell decisions | | 视网膜拓扑编码组织了内部和外部导向脑网络之间的对抗动态。 | Steel, A. | PDF | N/A | Retinotopic coding organizes the opponent dynamic between internally and externally oriented brain networks | | 利用多模态磁共振成像绘制白质通路的总体g-比率图 | Lu, W. D. | PDF | N/A | Mapping the aggregate g-ratio of white matter tracts using multi-modal MRI | | 最大化异构网络中的内存容量 | Zhang, K. | PDF | N/A | Maximizing memory capacity in heterogeneous networks | | JAK抑制剂撤药引发短暂性促炎级联反应：重大心脏不良事件的潜在机制 | Gurevic, I. | PDF | N/A | JAK Inhibitor Withdrawal Causes a Transient Proinflammatory Cascade: A Potential Mechanism for Major Adverse Cardiac Events | | 开发多物种qPCR检测方法用于应激转录谱（STP）芯片，以评估鲑科鱼类对环境变化的适应能力 | Islam, S. S. | PDF | N/A | Development of multi-species qPCR assays for a stress transcriptional profiling (STP) Chip to assess the resilience of salmonids to changing environments | | 环境富集减少adgrl3.1相关焦虑和注意力缺陷，但不影响冲动性 | Fontana, B. D. | PDF | N/A | Environmental Enrichment Reduces adgrl3.1-Related Anxiety and Attention Deficits but Not Impulsivity | | 翻译抑制剂春日霉素、依地因和GE81112在30S起始复合物形成过程中分别作用于不同的步骤。 | Safdari, H. A. | PDF | N/A | The translation inhibitors kasugamycin, edeine and GE81112 target distinct steps during 30S initiation complex formation | | Seed2LP：代谢网络中用于逆生态学应用的种子推断 | Ghassemi Nedjad, C. | PDF | N/A | Seed2LP: seed inference in metabolic networks for reverse ecology applications | | 四环状RNA片段的金属离子感应：非天然金属离子-RNA内壳接触的紧凑中间体的作用 | Habibullah, S. | PDF | N/A | Metal Ion Sensing by Tetraloop-Like RNA Fragment: Role of Compact Intermediates with Non-Native Metal Ion-RNA Inner Shell Contacts | | 前列腺癌骨转移的增强与EphA2非经典信号激活及配体缺乏的骨微环境有关 | Wang, B. | PDF | N/A | Skeletal Metastasis of Prostate Cancer Is Augmented by Activation of EphA2 Noncanonical Signaling and Ligand-Deficient Bone Microenvironment | | 多不饱和脂肪酸及其内源性大麻素相关代谢物在人源TRPV1和TRPA1离子通道上的活性，这些通道在HEK-293细胞中表达。 | Abate, A. A. | PDF | N/A | Polyunsaturated fatty acids and their endocannabinoid-related metabolites activity at human TRPV1 and TRPA1 ion channels expressed in HEK-293 cells. | | 皮层表征漂移的重尾统计特性对稳定下游读数具有优势。 | Micou, C. | PDF | N/A | Heavy-tailed statistics of cortical representational drift are advantageous for stabilised downstream readouts | | 衰老导致的体液稳态系统失调 | Jang, H. | PDF | N/A | Dysregulation of the fluid homeostasis system by aging | | 通过神经对比学习解读睡眠活动 | Chen, Z. | PDF | N/A | Interpreting Sleep Activity Through Neural Contrastive Learning | | 在7T磁共振成像（fMRI）单次扫描中同时测量反相编码EPI：亚毫米级fMRI中几何畸变校正的定量和定性评估 | Yun, S. D. | PDF | N/A | The Simultaneous Measurement of Reversed Phase-Encoding EPI in a Single fMRI Session at 7T: Quantitative and Qualitative Evaluation of Geometric Distortion Correction in Submillimetre fMRI | | 一种关于能量高效神经编码的响应稀疏性和变异性统一理论 | Huang, M. | PDF | N/A | A Unified Theory of Response Sparsity and Variability for Energy-Efficient Neural Coding | | 下丘脑连接性与年轻成人自我评估的攻击性 | Yao, Y. J. | PDF | N/A | Hypothalamic connectivities and self-evaluated aggression in young adults | | 在唐氏综合症模型中，成人补充胆碱可减少共病并改善认知能力 | Tallino, S. | PDF | N/A | Adult choline supplementation in a Down syndrome model reduces co-morbidities and improves cognition | | 执行功能障碍与雄性3xTg阿尔茨海默病模型小鼠海马-前额叶功能连接的改变有关 | Cunliffe, G. | PDF | N/A | Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in male 3xTg Alzheimer's model mice | | 视网膜辨别力对自然场景的适应性 | Ding, X. | PDF | N/A | Adaptation of retinal discriminability to natural scenes | | 目标单细胞表达谱分析鉴定出睡眠和代谢状态的整合者 | Shih, M.-F. M. | PDF | N/A | Targeted single cell expression profiling identifies integrators of sleep and metabolic state | | JZL184在体内慢性上调内源性大麻素信号对YAC128亨廷顿病小鼠纹状体突触可塑性和运动学习的影响 | Sepers, M. D. | PDF | N/A | Effect of chronic upregulation of endocannabinoid signaling in vivo with JZL184 on striatal synaptic plasticity and motor learning in YAC128 Huntington disease mice | | PKC eta 和 theta 对信号的不同解释控制着 T 细胞的功能和耗竭。 | Mann, T. H. | PDF | N/A | Different signaling interpretations by PKC eta and theta control T cell function and exhaustion | | 北极极端气候事件的增加与当地生物群落的负面适应性影响有关。 | Lemaire, M. C. | PDF | N/A | Increases in Arctic extreme climatic events are linked to negative fitness effects on the local biota | | 北极红点鲑（Salvelinus alpinus）小型孤立种群中依赖体型的生长率的时空变化 | Mittell, E. | PDF | N/A | Spatiotemporal variation in size-dependent growth rates in small isolated populations of Arctic charr (Salvelinus alpinus) | | 使《昆明-蒙特利尔全球生物多样性框架》的监测框架切实可行。 | Affinito, F. | PDF | N/A | Making the Monitoring Framework of the Kunming-Montreal Global Biodiversity Framework fit for purpose. | | 一个大规模的社区科学花卉颜色数据集揭示了北美红花植物中开花物候的趋同进化 | McKenzie, P. F. | PDF | N/A | A massive community-science flower color dataset reveals convergent evolution of delayed flowering phenology in North American red-flowering plants | | 性选择假说"解释警戒色的起源 | Maisonneuve, L. | PDF | N/A | The 'sexual selection hypothesis' for the origin of aposematism | | 伪毛滴虫属基氏伪毛滴虫的转录组与进化分析，这是一种自由生活的厌氧真核生物 | Abu-Elmakarem, H. | PDF | N/A | Transcriptome and evolutionary analysis of Pseudotrichomonas keilini, a free-living anaerobic eukaryote | | 不像其他针叶树：对英国普通刺柏（Juniperus communis）表型多样性的评估表明，残存种群之间存在遗传隔离和局部适应性。 | Baker, J. P. | PDF | N/A | Not like other conifers: evaluation of phenotypic diversity in British common juniper, Juniperus communis, indicates genetic isolation and local adaptations among remnant populations | | 利用镜像正向遗传学方法鉴定作用于核非编码RNA的人类通路 | Che, R. | PDF | N/A | Identification of Human Pathways Acting on Nuclear Non-Coding RNAs Using the Mirror Forward Genetic Approach | | α-D-甘露糖苷酶抑制剂（-）-苦马豆素的生物合成 | Liu, S. | PDF | N/A | Biosynthesis of the alpha-D-Mannosidase Inhibitor (-)-Swainsonine | | 发现利用SNAr化学的亲电降解剂 | Zhuang, Z. | PDF | N/A | Discovery of electrophilic degraders that exploit SNAr chemistry | | 利用成像质谱技术研究水凝胶扩张的小鼠脑组织中的脂质分布 | Samuel, J. M. | PDF | N/A | Examination of Lipid Distributions in Hydrogel-Expanded Mouse Brain Tissue Using Imaging Mass Spectrometry | | 确定特定肩部功能运动的最佳抗重力辅助水平：一项模拟研究 | Asgari, M. | PDF | N/A | Identifying an optimal anti-gravity assistance level for select functional shoulder movements: A simulation study | | 对牛津纳米孔测序数据集进行RNA修饰的定性回顾 | Pahar, M. | PDF | N/A | A qualitative review of Oxford Nanopore Sequencing datasets for RNA modifications | | FishCODE：一个基于网络的信息平台，用于全面探索鱼类研究中的组学数据 | Li, H. | PDF | N/A | FishCODE: a web-based information platform for comprehensive omics data exploration in fish research | | 多视角综合方法用于填补短链脂肪酸并识别预测血液SCFA的关键因素 | Liu, A. | PDF | N/A | Multi-View Integrative Approach For Imputing Short-Chain Fatty Acids and Identifying Key factors predicting Blood SCFA | | Unipept 6.0：扩展元蛋白质组学分析，支持漏切、半胰蛋白酶和非胰蛋白酶肽 | Vande Moortele, T. | PDF | N/A | Unipept 6.0: Expanding metaproteomics analysis with support for missed cleavages, semi-tryptic and non-tryptic peptides | | 扭转是机械敏感离子通道NOMPC门控的关键 | Duan, J. | PDF | N/A | Twist is the key to the gating of mechanosensitive ion channel NOMPC | | 双峰细胞质量分布将CD8+ T细胞分为两种不同类型，其分化动力学截然不同。 | Yu, J. | PDF | N/A | Bimodal cell mass distribution separates CD8+ T cells into two distinct types with divergentdifferentiation dynamics | | 流明电荷控制β-桶纳米孔中的离子传输 | Mayer, S. F. | PDF | N/A | Lumen charge governs ion transport in β-barrel nanopores | | 弱的、特定的化学相互作用决定了巴纳西在不同细胞环境中的稳定性 | Tahir, U. | PDF | N/A | Weak, specific chemical interactions dictate barnase stability in diverse cellular environments | | ER+乳腺癌中的内分泌持续伴随着氧化磷酸化中的代谢脆弱性 | Tau, S. | PDF | N/A | Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation | | 过度表达白细胞介素6的胰腺癌细胞可引发T细胞介导的肿瘤清除及持久的抗肿瘤免疫反应。 | Arneson-Wissink, P. C. | PDF | N/A | Pancreatic cancer cells overexpressing interleukin 6 induce T-cell-mediated tumor clearance and durable anti-tumor immune response | | 单细胞转录组分析：治疗后和未治疗结直肠癌的潜在耐药机制探究 | Puzanov, G. A. | PDF | N/A | Single-cell Transcriptome Profiling of Post-treatment and Treatment-naive Colorectal Cancer: Insights into Putative Mechanisms of Chemoresistance | | FRMD8调控tmTNF-α在三阴性乳腺癌转移中的加工：对分子通路动态的洞察 | Xu, J. | PDF | N/A | Regulation of tmTNF-α Processing by FRMD8 in Triple-Negative Breast Cancer Metastasis: Insights into Molecular Pathway Dynamics | | MALT1蛋白酶抑制通过逆转肿瘤相关巨噬细胞依赖的免疫抑制，抑制胶质母细胞瘤的进展。 | Hofstatter Azambuja, J. | PDF | N/A | MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression | | 联合PARP14抑制与PD-1阻断可促进细胞毒性T细胞静息，并调节复发性黑色素瘤中的巨噬细胞极化 | Leshem, R. | PDF | N/A | Combined PARP14 Inhibition and PD-1 Blockade Promotes Cytotoxic T Cell Quiescence and Modulates Macrophage Polarisation in Relapsed Melanoma | | 2023年生长季节澳大利亚燕麦冠锈菌致病性特征分析 | Nguyen, D. T. | PDF | N/A | Characterisation of virulence of Puccinia coronata f. sp. avenae in Australia in the 2023 growing season | | 萌发前温度条件对温带草原物种萌发特性的影响 | Kiss, R. | PDF | N/A | Effect of pre-germination temperature conditions on germination characteristics of temperate grassland species | | 从肿瘤微环境到实体瘤的免疫治疗结果：一种系统理论方法 | Bhattacharya, P. | PDF | N/A | From tumor microenvironment to immuno-therapeutic outcomes for solid tumors: A systems theoretic approach | | 大肠杆菌I类和II类氨酰tRNA合成酶的氨酰化动力学经验模型 | Dykeman, E. C. | PDF | N/A | An empirical model of aminoacylation kinetics for E. coli class I and II aminoacyl tRNA synthetases | | 抑郁症中的异质性食欲模式：营养内感受、奖赏处理与决策制定的计算建模 | Uchida, Y. | PDF | N/A | Heterogeneous Appetite Patterns in Depression: Computational Modeling of Nutritional Interoception, Reward Processing, and Decision-Making | | 超快速多器官蛋白质组学揭示了药物疗效和毒性的组织特异性机制 | Xiong, Y. | PDF | N/A | Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity | | 评估高密度表面肌电图描述符对解剖和神经特性随年龄变化的敏感性：一项模拟研究 | Douania, I. | PDF | N/A | Evaluation of HD-sEMG descriptor sensitivity to changes of anatomical and neural properties with aging : A simulation study | | 在任务学习过程中，新皮质各区域之间协调的多层次适应 | Han, S. | PDF | N/A | Coordinated multi-level adaptations across neocortical areas during task learning | | 睡眠调节人脑皮层中的神经时间尺度和时空整合 | Cusinato, R. | PDF | N/A | Sleep modulates neural timescales and spatiotemporal integration in the human cortex | | 解开发放率适应性使得群体编码保持不变 | Brandao, S. C. | PDF | N/A | Undoing of firing rate adaptation enables invariant population codes | | 在假体视觉下最小化物体识别所需的视网膜光幻视数量 | Scialom, E. | PDF | N/A | Minimizing the number of phosphenes required for object recognition under prosthetic vision | | 自然场景中大小恒常性的神经时间进程 | Yeh, L.-C. | PDF | N/A | The neural time course of size constancy in natural scenes | | 结核分枝杆菌MutT1 Nudix水解酶结构域的非典型活性作为蛋白磷酸酶调控核苷二磷酸激酶（NDK）功能 | Emam, E. A. F. | PDF | N/A | An unusual activity of mycobacterial MutT1 Nudix hydrolase domain as a protein phosphatase regulates nucleoside diphosphate kinase (NDK) function | | 小型真核浮游植物在铁限制区域中对碳输出的作用可能远超其规模。 | Meyer, M. G. | PDF | N/A | Small eukaryotic phytoplankton can play an outsized role in carbon export in iron-limited regions | | 来自海洋基因监测计划ARMS-MBON 2018-2020的长期生态研究数据集 | Daraghmeh, N. | PDF | N/A | A long-term ecological research data set from the marine genetic monitoring programme ARMS-MBON 2018-2020 | | 影响南美洲金蝇（双翅目：丽蝇科）种群结构的人口统计和历史过程 | Souza, K. | PDF | N/A | Demographic and Historical Processes Influencing Cochliomyia hominivorax (Diptera: Calliphoridae) Population Structure across South America | | 具有高远端遗传力的转录本介导了遗传因素对复杂代谢性状的影响。 | Tyler, A. L. | PDF | N/A | Transcripts with high distal heritability mediate genetic effects on complex metabolic traits | | 历史性破碎的英国普通刺柏（Juniperus communis L.）种群之间遗传隔离和分化的证据 | Baker, J. P. | PDF | N/A | Evidence of genetic isolation and differentiation among historically fragmented British populations of common juniper, Juniperus communis L. | | 通过比较基因组分析鉴定马拉色菌属物种中假定的端粒酶RNA亚基编码基因 | Sanpedro-Luna, J. A. | PDF | N/A | Identification of the putative gene encoding the RNA subunit of telomerase in Malassezia clade species through comparative genomic analysis | | 结合基因表达和环境因素可提高小麦性状的基因组预测 | Liu, J. | PDF | N/A | Incorporating gene expression and environment improves genomic prediction of wheat traits | | 激光散斑粒度仪（SPARSE）揭示了组织颗粒度的大小分布 | Hajjarian, Z. | PDF | N/A | Laser Speckle Particle Sizer (SPARSE) Informs the Size Distribution of Tissue Granularities | | 重新评估一些结构相似但机制不同的流行CRAC通道抑制剂？ | Gokce, Y. | PDF | N/A | Re-evaluation of some popular CRAC channel inhibitors structurally similar but mechanistically different? | | 小说色彩视觉评估工具：AIM 色彩检测与辨别 | He, J. | PDF | N/A | Novel color vision assessment tool: AIM Color Detection and Discrimination | | RNA结合蛋白敲低后iNeurons中mRNA转运和局部翻译的改变 | Dargan, R. L. | PDF | N/A | Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown | | 新型神经启发式控制器通过内部模型在较低的肢体任务中推广模块化 | Munoz, D. | PDF | N/A | New neural-inspired controller generalises modularity over lower limb tasks through internal models | | 以乙醇为唯一碳源和能源的条件下，酵母菌的特定生长速率和生长化学计量学 | Warmerdam, M. | PDF | N/A | Specific growth rates and growth stoichiometries of Saccharomycotina yeasts on ethanol as sole carbon and energy substrate | | 肿瘤微环境调控头颈部鳞状细胞癌免疫治疗预后格局：基于计算模型的分析 | Bhattacharya, P. | PDF | N/A | Tumor microenvironment governs the prognostic landscape of immunotherapy for head and neck squamous cell carcinoma: A computational model-guided analysis | | 通过体内超突变进行的氨酰-tRNA合成酶的定向进化 | Furuhata, Y. | PDF | N/A | Directed evolution of aminoacyl-tRNA synthetases through in vivo hypermutation | | 通过工程改造从宏基因组中发现的新型Cas12a同源蛋白，扩展CRISPR工具箱 | Tao, D. | PDF | N/A | Expanding the CRISPR toolbox by engineering Cas12a orthologs of metagenomic discovery | | HU促进高阶染色体组织，并影响肺炎链球菌中的DNA复制速率。 | Mazzuoli, M.-V. | PDF | N/A | HU promotes higher-order chromosome organisation and influences DNA replication rates in Streptococcus pneumoniae | | 多糖生物合成中的耐受机制：对大肠杆菌和福氏志贺菌中十一碳烯醇磷酸回收的启示 | Qin, J. | PDF | N/A | Tolerance Mechanisms in Polysaccharide Biosynthesis: Implications for Undecaprenol Phosphate Recycling in Escherichia coli and Shigella flexneri | | 通过sdiA突变揭示的肺炎克雷伯菌毒力和噬菌体敏感性的调控作用 | Silva-Bea, S. | PDF | N/A | Regulatory effects on virulence and phage susceptibility revealed by sdiA mutation in Klebsiella pneumoniae | | 肠致病性大肠杆菌通过减少牵引力，在富含纤连蛋白的基质上诱导溶组织内阿米巴的Levy样运动 | Guo, Y. | PDF | N/A | Enteropathogenic Escherichia coli induces Entamoeba histolytica Levy-like movement on fibronectin-rich substrate by reducing traction forces | | 关键激酶TgGSK调控弓形虫中心体分裂和内二分裂 | Krueger, A. | PDF | N/A | The essential kinase TgGSK regulates centrosome division and endodyogeny in Toxoplasma gondii | | 霍乱弧菌CsrA通过增加toxR mRNA的稳定性和翻译来控制ToxR的水平。 | Mey, A. R. | PDF | N/A | Vibrio cholerae CsrA controls ToxR levels by increasing the stability and translation of toxR mRNA | | 将荧光蛋白插入MotB的塞域附近可生成功能性定子复合体。 | Gurung, J. P. | PDF | N/A | Insertion of fluorescent proteins near the plug domain of MotB generates functional stator complex. | | 气候波动调节了与病原体动态相关的生态进化过程，并继续加剧番茄细菌性斑点病害的流行。 | Bhandari, R. | PDF | N/A | Climatic fluctuations modulate eco-evolutionary processes associated with pathogen dynamics and continue to fuel bacterial spot epidemics in tomato | | 单细胞变异与细胞系中表型异质性的快速出现——CRISPR-Cas9忠实追随者的一则警示故事。 | Bradley, H. | PDF | N/A | Single cell variation and rapid emergence of phenotypic heterogeneity in cell lines- a cautionary tale for devotees of CRISPR-Cas9. | | 鉴定Saccharolobus islandicus REY15A中Ced和Ups系统的新组分 | Shen, Y. | PDF | N/A | Identification of novel components of the Ced and Ups systems in Saccharolobus islandicus REY15A | | 植物、土壤和商业生物制品中致病性和非致病性木霉菌株的系统发育分析简称：木霉菌株的系统发育分析 | Pfordt, A. | PDF | N/A | Phylogenetic analysis of pathogenic and non-pathogenic Trichoderma isolates from plants, soil and commercial bio products Short titel: Phylogenetic analysis of pathogenic and non-pathogenic Trichoderma isolates | | 关于鳐类中细菌和寄生虫的元分析综述揭示了研究空白 | Modzelesky, A. | PDF | N/A | Meta-analytic Review of Bacteria and Parasites in Elasmobranchs Provides Insight into Research Gaps | | 阴道毛滴虫中的TvAP65通过与宿主分子相互作用促进HPV感染 | Mei, X. | PDF | N/A | TvAP65 in Trichomonas vaginalis Promotes HPV Infection by Interacting with Host Molecules | | 结核分枝杆菌通过大量改造其脂质组，使用无磷脂质，从而克服磷酸盐饥饿。 | Gray, R. M. | PDF | N/A | Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids | | 硫酸盐还原菌代谢和应激反应中硫氧还蛋白的常见与非常见功能 | Majumder, E. L.- W. | PDF | N/A | The usual and unusual functions of thioredoxins in the metabolism and stress-response of sulfate-reducing bacteria | | 不同个体的人类肠道微生物组样本中，大肠杆菌生态成功的驱动因素各异。 | Boumasmoud, M. | PDF | N/A | Drivers of ecological success for Escherichia coli vary among human gut microbiome samples from different individuals | | 评估金盏花（Tagetes erecta）酒精提取物对临床重要细菌和真菌的抗菌活性。 | Martinez Gonzalez, G. | PDF | N/A | Evaluation of the antimicrobial activity of the alcoholic extract of Tagetes erecta against bacteria and fungi of clinical importance. | | 目前，源自牛的H5N1流感病毒的血凝素基因仍保留着禽流感病毒的表型。 | Yang, J. | PDF | N/A | The Haemagglutinin Gene of Bovine Origin H5N1 Influenza Viruses Currently Retains an Avian Influenza Virus phenotype. | | 评估Ruta chalepensis、Hippocratea excelsa、Litsea glaucescens和Waltheria americana的乙醇提取物对耐甲氧西林金黄色葡萄球菌的抗菌活性 | Martinez Gonzalez, G. | PDF | N/A | Evaluation of antibacterial activity of ethanolic extracts of Ruta chalepensis, Hippocratea excelsa, Litsea glaucescens and Waltheria americana against methicillin-resistant Staphylococcus aureus | | 结构导向设计、合成及表征C22和C32修饰的FK520类似物，其对人致病真菌的活性增强 | Dome, P. A. | PDF | N/A | Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi | | 对新型竞争性诱导的链球菌肽聚糖水解酶的自免疫由一种类似Fem转移酶的蛋白质介导 | Marli, M. T. | PDF | N/A | Self-immunity towards a novel competence-induced streptococcal murein hydrolase is mediated by a Fem-transferase-like protein | | 使用高斯混合模型和深度神经网络从异质性冷冻电镜结构中构建分子模型系列 | Chen, M. | PDF | N/A | Building molecular model series from heterogeneous CryoEM structures using Gaussian mixture models and deep neural networks | | snoRNP分子伴侣snR190与Npa1复合体共同形成了一个大分子装配体，该装配体对于60S核糖体亚基的成熟是必需的。 | Hamze, H. | PDF | N/A | The snoRNP chaperone snR190 and the Npa1 complex form a macromomecular assembly required for 60S ribosomal subunit maturation | | 压力易感性的神经蓝图：与压力后果相关的大脑广泛神经活动 | Dirven, B. C. J. | PDF | N/A | The Neural Blueprint of Stress Susceptibility: Brain-wide neuronal activity associated with the consequences of stress | | 内在注意力和外在注意力之间的动态认知差异与抑郁和焦虑障碍有关。 | Oka, T. | PDF | N/A | Dynamic cognitive differences between internal and external attention are associated with depressive and anxiety disorders | | 记忆编码的预测性影响：研究振荡与N400事件相关电位成分 | Jano, S. L. | PDF | N/A | Predictive influences on memory encoding: investigating oscillations and the N400 event-related potential component | | 在记忆形成过程中，内嗅皮层对视觉空间的网格状编码 | Graichen, L. P. | PDF | N/A | Entorhinal grid-like codes for visual space during memory formation | | 丰度测量揭示了人类肠道微生物群中裂解与溶原之间的平衡 | Lopez, J. | PDF | N/A | Abundance measurements reveal the balance between lysis and lysogeny in the human gut microbiome | | 描绘社会行为的图景 | Klibaite, U. | PDF | N/A | Mapping the landscape of social behavior | | 通过调节前额叶皮层的反应性，屏状核增强了神经变异性。 | Atilgan, H. | PDF | N/A | The claustrum enhances neural variability by modulating the responsiveness of the prefrontal cortex | | 在斑胸草雀中，毫秒级别的运动控制先于感觉运动学习 | Pascual, L. M. | PDF | N/A | Millisecond-scale motor control precedes sensorimotor learning in Bengalese finches | | 激活I组代谢型谷氨酸受体对于小鼠海马中异突触性长期增强的预备是必需的。 | Koek, L. A. | PDF | N/A | Activation of group I mGluRs is required for heterosynaptic priming of long-term potentiation in mouse hippocampus | | 浦肯野细胞的内在活动塑造了小脑的发育和功能 | Osorio, C. | PDF | N/A | Purkinje cell intrinsic activity shapes cerebellar development and function | | KCNC1癫痫性脑病新型小鼠模型中快速放电神经元兴奋性受损 | Wengert, E. R. | PDF | N/A | Impaired excitability of fast-spiking neurons in a novel mouse model of KCNC1 epileptic encephalopathy | | 人海马体中的正负视网膜拓扑编码 | Angeli, P. A. | PDF | N/A | Positive and Negative Retinotopic Codes in the Human Hippocampus | | 抑制性可塑性调控的时间精度与效应幅度之间的权衡决定了学习表征的可分离性。 | Rubisch, P. | PDF | N/A | The trade-off between temporal precision and effect amplitude of inhibitory plasticity regulation determines separability of learned representations | | 斯里兰卡蝙蝠中发现致病性钩端螺旋体：潜在的宿主风险首次报告 | Perera, T. | PDF | N/A | First report of pathogenic Leptospira in Sri Lankan bats: A potential reservoir risk | | 在H5N1疫情爆发后，共域海鸟物种之间的无症状感染和同时发生的禽流感病毒抗体流行率存在显著差异。 | Greco, F. | PDF | N/A | Asymptomatic infection and antibody prevalence to co-occurring avian influenza viruses vary substantially between sympatric seabird species following H5N1 outbreaks |

BioRxiv 2024-09-25 Papers

标题	作者	PDF链接	代码仓库	Title
从发育到成年，整合的肢骨单细胞图谱	Herpelinck, T.	PDF	N/A	An integrated single-cell atlas of the limb skeleton from development through adulthood
人类语言中的一个伴随放电回路	Khalilian-Gourtani, A.	PDF	N/A	A Corollary Discharge Circuit in Human Speech
冬季体重变化在狍（Capreolus capreolus）种群中始终表现出性别特异性。	Hewison, A. J. M.	PDF	N/A	Body mass change over winter is consistently sex-specific across roe deer (Capreolus capreolus) populations
优化和基准测试基于全基因组关联研究（GWAS）摘要统计的复杂疾病风险评分	Zhao, Z.	PDF	N/A	Optimizing and benchmarking polygenic risk scores with GWAS summary statistics
依赖于价值的突触可塑性在社交情境中驱动接近和回避行为	Espinosa, P.	PDF	N/A	Valence-dependent synaptic plasticity drives approach and avoidance behavior in social context
二聚化热力学调控生物相分离	Dubach, M.	PDF	N/A	Dimerization thermodynamics govern biological phase separation
利用单细胞RNA测序数据对批量组织中细胞丰度进行独立于聚类的估计	Aubin, R. G.	PDF	N/A	Clustering-independent estimation of cell abundances in bulk tissues using single-cell RNA-seq data
HiExM：高通量扩展显微技术实现可扩展的超分辨率成像	Day, J. H.	PDF	N/A	HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging
急性应激后内啡肽动态变化的高度灵敏体内检测	Mikati, M. O.	PDF	N/A	Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress
通过单一类别的中间神经元实现的分层行为控制	Huo, J.	PDF	N/A	Hierarchical behavior control by a single class of interneurons
视神经损伤后，ATF4协调激活轴突再生和神经退行性转录程序	Somasundaram, P.	PDF	N/A	Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury
泛组织转录组分析揭示了人类衰老的性别二态性	Wang, S.	PDF	N/A	Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human Aging
使用视觉悬崖和杆下降实验检测小鼠的双眼干扰	De Jesus-Cortes, H.	PDF	N/A	Using the visual cliff and pole descent assays to detect binocular disruption in mice
老年PANX3敲除小鼠的严重骨关节炎：对新型原发性骨关节炎模型的启示	Wakefield, B.	PDF	N/A	Severe Osteoarthritis in Aged PANX3 Knockout Mice: Implications for a Novel Primary Osteoarthritis Model
通过相位图和模糊递归图探索大脑功能的非线性动力学	Li, Q.	PDF	N/A	Exploring Nonlinear Dynamics In Brain Functionality Through Phase Portraits And Fuzzy Recurrence Plots
小脑将输入数据转换成超低分辨率的3D像素。谁知道呢？	Gilbert, M.	PDF	N/A	THE CEREBELLUM CONVERTS INPUT DATA INTO HYPER LOW-RESOLUTION 3-D PIXELS. WHO KNEW?
超快功率多普勒超声能够纵向追踪血管变化，这些变化与放射治疗后的免疫反应相关。	Martello, S. E.	PDF	N/A	Ultrafast Power Doppler Ultrasound Enables Longitudinal Tracking of Vascular Changes that Correlate with Immune Response After Radiotherapy
癫痫传播在海马局部卒中期间主要在自由活动的雌性小鼠中触发了对侧病灶的扩散性去极化保护反应。	Boyce, A. K.	PDF	N/A	Seizure propagation triggers a protective contralesional spreading depolarization during focal hippocampal stroke predominantly in freely behaving female mice
凝聚素在秀丽隐杆线虫中组织围绕活性增强子的三维DNA接触	Kim, J.	PDF	N/A	Cohesin organizes 3D DNA contacts surrounding active enhancers in C. elegans
元认知体验的时间动态与任务表现中的理性适应相吻合。	Vermeylen, L.	PDF	N/A	The Temporal Dynamics of Metacognitive Experiences Track Rational Adaptations in Task Performance
迷幻剂的协同、多层次理解：对其药理学、神经影像学和现象学的三次系统综述与元分析	Shinozuka, K.	PDF	N/A	Synergistic, Multi-level Understanding of Psychedelics: Three Systematic Reviews and Meta-analyses of Their Pharmacology, Neuroimaging and Phenomenology
乳腺导管原位癌的单细胞表达分析揭示了上皮完整性的改变	Qin, X.	PDF	N/A	Single Cell Expression Analysis of Ductal Carcinoma in Situ Identifies Alterations in Epithelial Integrity
自闭症候选基因rbm-26（RBM26/27）通过调控MALS-1在神经发育过程中保护线粒体功能和轴突免受退化。	Chowdhury, T. A.	PDF	N/A	Autism candidate gene rbm-26(RBM26/27) regulates MALS-1 to protect against mitochondrial dysfunction and axon degeneration during neurodevelopment.
将人口和扩散的时空变化对集合种群增长率的影响进行分区	Schreiber, S.	PDF	N/A	Partitioning the Impacts of Spatial-Temporal Variation in Demography and Dispersal on Metapopulation Growth Rates
家麻雀（Passer domesticus）全基因组测序与组装	Kumar, V.	PDF	N/A	Whole Genome Sequencing and Assembly of the House Sparrow, Passer domesticus
磷酸蛋白质组学分析鉴定REPS1为骨骼肌中胰岛素和运动应答的葡萄糖摄取信号转导器	Kjaergaard, J.	PDF	N/A	Phosphoproteomic Analysis Identifies REPS1 as an Insulin- and Exercise-Responsive Signal Transducer to Glucose Uptake in Skeletal Muscle
一种重要抗寒油菜种质的全基因组组装与基因组结构	Wu, Z.	PDF	N/A	Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm
非破坏性X射线断层扫描技术对脑组织超微结构的分析	Bosch, C.	PDF	N/A	Non-destructive X-ray tomography of brain tissue ultrastructure
使用Recomb-Mix进行快速准确的本地祖先推断	Wei, Y.	PDF	N/A	Fast and accurate local ancestry inference with Recomb-Mix
肿瘤内氯气二氧化物递送利用其类ROS特性：一种有效癌症治疗的新范式	Liu, X.	PDF	N/A	Intratumoral Delivery of Chlorine Dioxide Exploits its ROS-like Properties: A Novel Paradigm for Effective Cancer Therapy
高粱基因组-表型关联的GWAS后优先级排序	Pal, D.	PDF	N/A	Post-GWAS Prioritization of Genome-Phenome Associations in Sorghum
雌激素对奖赏预测误差和强化学习的影响	Golden, C. E. M.	PDF	N/A	Estrogenic control of reward prediction errors and reinforcement learning
Sinorhizobium fredii USDA257 的 VI 型分泌系统对于与大豆 Pekin 品种的成功共生是必需的。	Reyes-Perez, P.	PDF	N/A	The type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful symbiosis with Glycine max cv Pekin
成年雌性大鼠的嗅鞘细胞是一种混合胶质细胞，能够促进神经修复。	Phelps, P. E.	PDF	N/A	Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair
运动记忆形成的核心：双手适应中的时间泛化	Howard, I. S.	PDF	N/A	Kernels of Motor Memory Formation: Temporal Generalization in Bimanual Adaptation
脑癌相关结合域突变揭示了CTCF与染色质的关系及其对基因调控的贡献	Do, C.	PDF	N/A	Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its contribution to gene regulation
在Pol II触发环单倍型内的高阶上位性	Duan, B.	PDF	N/A	Higher-order epistasis within Pol II trigger loop haplotypes
分布式皮层区域在工作记忆存储中具有不同的表征角色	Chopurian, V.	PDF	N/A	Distinct representational roles of distributed cortical regions for working memory storage
海洋微生物之间嘌呤和嘧啶交叉喂养的全球生态位划分	Braakman, R.	PDF	N/A	Global niche partitioning of purine and pyrimidine cross-feeding among ocean microbes
单核多组学揭示了小鼠原始生殖细胞性别决定背后的基因调控网络	Alexander, A. K.	PDF	N/A	Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells
通过序列过滤，反复出现的皮质网络编码了自然感官统计数据。	Deveau, C.	PDF	N/A	Recurrent cortical networks encode natural sensory statistics via sequence filtering
评估预训练的DNA语言模型在调控基因组学中的表征能力	Tang, Z.	PDF	N/A	Evaluating the representational power of pre-trained DNA language models for regulatory genomics
PPFlow：基于扭转流匹配的目标感知肽设计	Lin, H.	PDF	N/A	PPFlow: Target-aware Peptide Design with Torsional Flow Matching
脂质过氧化与I型干扰素的耦合作用促进了致病性巨噬细胞的激活，导致结核病易感性增加。	Yabaji, S. M.	PDF	N/A	Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
从表面和深度电极信号进行主题无关的基于Transformer的神经语音解码	Chen, J.	PDF	N/A	Subject-Agnostic Transformer-Based Neural Speech Decoding from Surface and Depth Electrode Signals
赋能未来科学家：导师们采用多种策略，引导学生参与专业科学学科素养实践	Minocha, T.	PDF	N/A	Empowering future scientists: Mentors employ various strategies to engage students in professional science disciplinary literacy practices
MOSAIC：一种高效、一步到位的重组工程方法，用于质粒编辑与多样化	van den Brink, M.	PDF	N/A	MOSAIC: a highly efficient, one-step recombineering approach to plasmid editing and diversification
在开花期间，甘蓝型油菜（Brassica napus）长期受到热应激会负面影响产量，并改变硫代葡萄糖苷和糖类的代谢。	Kourani, M.	PDF	N/A	Prolonged heat stress in Brassica napus during flowering negatively impacts yield and alters glucosinolate and sugars metabolism
Fmo5在杯状细胞成熟和粘液屏障形成中发挥性别特异性作用	Schaller, M. L.	PDF	N/A	Fmo5 plays a sex-specific role in goblet cell maturation and mucus barrier formation
WHIRLY1 调控拟南芥早期幼苗发育中的脂肪族硫代葡萄糖苷生物合成	Nguyen, L. T.	PDF	N/A	WHIRLY1 regulates aliphatic glucosinolate biosynthesis in early seedling development of Arabidopsis
内在单位：识别系统因果关系的颗粒度。	Marshall, W.	PDF	N/A	Intrinsic Units: Identifying a system's causal grain.
结肠癌的转移需要Dickkopf-2来生成具有潘氏细胞特性的癌细胞。	Shin, J. H.	PDF	N/A	Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties
蜘蛛社会性的基因组后果及持久性	Ma, J.	PDF	N/A	The genomic consequences and persistence of sociality in spiders
品尝硬度？植物肉和动物肉的机械特征	St. Pierre, S. R.	PDF	N/A	Tasting stiffness? The mechanical signature of plant-based and animal meat
发育中的少突胶质细胞通过调节同步自发活动来调控大脑功能。	Masumura, R.	PDF	N/A	Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity
颈动脉体血管紧张素信号的表观遗传上调增加了血压	Zhu, F.	PDF	N/A	Epigenetic upregulation of carotid body angiotensin signaling increases blood pressure
GeoAB：迈向现实抗体设计与可靠亲和力成熟	LIN, H.	PDF	N/A	GeoAB: Towards Realistic Antibody Design and Reliable Affinity Maturation
靶向抗癌前乙烯砜碳酸酐酶IX共价抑制剂	Vaskevicius, A.	PDF	N/A	Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX
Oxydifficidin是一种强效的淋病奈瑟菌抗生素，其作用机制涉及DedA辅助摄取和核糖体蛋白RplL的敏感性。	Kan, J.	PDF	N/A	Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity
多组学分析揭示了亚麻荠（Camelina sativa）和其他十字花科植物种子中特化代谢物的组成和空间分布的对比情况。	Barreda, L.	PDF	N/A	Multi-omic analyses unveil contrasting composition and spatial distribution of specialized metabolites in seeds of Camelina sativa and other Brassicaceae
分子和空间转录组学分类中脑多巴胺神经元及其在帕金森病LRRK2G2019S模型中的改变	Gaertner, Z.	PDF	N/A	Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease
IGF2BP3通过靶向FBXO32激活cGMP-PKG信号通路，从而促进胃癌的进展。	Si, Y.	PDF	N/A	IGF2BP3 promotes the progression of gastric cancer by activating cGMP-PKG signaling pathway via targeting FBXO32
一种可微分的Gillespie算法，用于模拟化学动力学、参数估计和设计合成生物电路	Rijal, K.	PDF	N/A	A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits
NR2F2在胚胎睾丸中对胎儿间质细胞的发育是必需的。	Perea-Gomez, A.	PDF	N/A	NR2F2 is required in the embryonic testis for Fetal Leydig Cell development
通过圆二色谱和分子建模解析TMPRSS2信使RNA中的鸟嘌呤四链体结构	D'Anna, L.	PDF	N/A	Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling
利用大型语言模型解码EB病毒相关疾病的关键靶点和信号通路	Yu, J.	PDF	N/A	Decoding critical targets and signaling pathways in EBV-mediated diseases using large language models
7K和11K SomaScan血浆蛋白质组学检测的变异性	Candia, J.	PDF	N/A	Variability of 7K and 11K SomaScan plasma proteomics assays
食欲素神经元群体活动精确地反映了在行为和代谢状态下净身体运动的变化。	Tesmer, A. L.	PDF	N/A	Orexin population activity precisely reflects net body movement across behavioral and metabolic states
小檗碱是一种新型线粒体钙单向转运体（MCU）抑制剂，能够破坏MCU-EMRE复合体的组装。	Zhao, H.	PDF	N/A	Berberine is a novel mitochondrial calcium uniporter (MCU) inhibitor that disrupts MCU-EMRE assembly
通过脑转移性黑色素瘤模型揭示的免疫疗法反应的免疫和分子相关性。	Daugherty-Lopes, A.	PDF	N/A	IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY REVEALED BY BRAIN-METASTATIC MELANOMA MODELS.
果蝇属物种间雌性攻击性的差异是否与繁殖潜力相关？	Bath, E.	PDF	N/A	Is variation in female aggressiveness across Drosophila species associated with reproductive potential?
肠道菌群是ALS相关TDP43小鼠性二态性的决定因素	Beraldi, E. J.	PDF	N/A	The gut microbiota is a determinant of sexual dimorphism in ALS-linked TDP43 mice
红细胞生成素依赖的CD235a-早期红系祖细胞中CD71hiCD105hi表型的获得	Schippel, N.	PDF	N/A	Erythropoietin-dependent Acquisition of CD71hiCD105hi Phenotype within CD235a- Early Erythroid Progenitors
引入白三叶草（Trifolium repens L.）后抗旱策略的演变	Hendrickson, B. T.	PDF	N/A	Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.)
优化后的扩展显微技术揭示了非洲爪蟾卵提取物中物种特异性的纺锤体微管组织	Guilloux, G.	PDF	N/A	Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts
适应性觉醒调节：通过儿茶酚胺增强觉醒来药理学地改变耶克斯-多德森曲线的峰值	Beerendonk, L.	PDF	N/A	Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal
横断面脑龄评估在预测未来脑变化方面存在局限性。	Korbmacher, M.	PDF	N/A	Cross-sectional brain age assessments are limited in predicting future brain change
识别生长分化因子-15作为代谢功能障碍相关脂肪性肝炎的早期预测生物标志物：基于英国生物样本库蛋白质组数据的嵌套病例对照研究	Wang, H.	PDF	N/A	Identification of Growth Differentiation Factor-15 as An Early Predictive Biomarker for Metabolic Dysfunction-Associated Steatohepatitis: A Nested Case-control Study of UK Biobank Proteomic Data
肌醇六磷酸（InsP6）通过激活HDAC1/3表观遗传轴来维持肠道屏障功能	Chatterjee, S.	PDF	N/A	Inositol Hexaphosphate (InsP6) Activates the HDAC1/3 Epigenetic Axis to Maintain Intestinal Barrier Function
ArchMap：基于参考的单细胞数据集分析的网络平台	Lotfollahi, M.	PDF	N/A	ArchMap: A web-based platform for reference-based analysis of single-cell datasets
使用整合和抗CRISPR（IntAC）技术在果蝇细胞中进行高分辨率的全基因组CRISPR敲除筛选	Viswanatha, R.	PDF	N/A	Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC)
BrainUnit：将物理单位融入高性能AI驱动的科学计算	Wang, C.	PDF	N/A	BrainUnit: Integrating Physical Units into High-Performance AI-Driven Scientific Computing
亚洲狼的复杂基因组祖先及其在南方的分布，以及推动大陆层面遗传多样性的因素	Hennelly, L.	PDF	N/A	Complex genomic ancestry in southern regions and drivers of continental-level genetic diversity in the wolves of Asia
造血干细胞来源的脂肪细胞的消融减少了同基因小鼠高级别浆液性癌模型中的肿瘤负担	Woodruff, E. R.	PDF	N/A	Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma
苜蓿（Medicago truncatula）中的CORYNE基因调控花序分生组织分支、营养信号传递以及丛枝菌根共生关系	Orosz, J.	PDF	N/A	Medicago truncatula CORYNE regulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis
CHAMP1复合物指导异染色质组装并促进同源定向DNA修复	Li, F.	PDF	N/A	CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair
在单细胞RNA测序中，利用scPCA联合建模细胞异质性和条件效应	Vohringer, H. S.	PDF	N/A	Joint Modeling of Cellular Heterogeneity and Condition Effects with scPCA in Single-Cell RNA-Seq
超级增强子分析揭示了ThPOK/ZBTB7B，作为CD4+细胞谱系承诺因子，是一个主调控因子，限制乳腺癌细胞呈现腔内非迁移表型。	Arcuschin, C. D.	PDF	N/A	Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype
丙戊酸对髓母细胞瘤中干细胞性和分化调节因子的调控	Freire, N. H.	PDF	N/A	Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma
脂肪细胞代谢状态调节神经胶质细胞的吞噬功能	Alassaf, M.	PDF	N/A	Adipocyte metabolic state regulates glial phagocytic function
组成型活性硝酸还原酶的表达增加了尼古丁拟南芥叶片中SARS-CoV-2刺突蛋白的产量，这些叶片原本表现出衰老的特征。	Hamel, L.-P.	PDF	N/A	Expression of a constitutively active nitrate reductase increases SARS-CoV-2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence
一种基于酵母的反向遗传系统，用于生成编码第八个sgRNA的HCoV-OC43报告病毒	Duguay, B.	PDF	N/A	A yeast-based reverse genetics system to generate HCoV-OC43 reporter viruses encoding an eighth sgRNA
五年间关注的新冠病毒变种中，针对刺突蛋白的中和抗体动态变化揭示了保护免受严重COVID-19的保守表位	Zayou, L.	PDF	N/A	Dynamics of Spike-Specific Neutralizing Antibodies Across Five-Year Emerging SARS-CoV-2 Variants of Concern Reveal Conserved Epitopes that Protect Against Severe COVID-19
探索老年人重症COVID-19的生物学机制：来自老年小鼠模型的见解	Ma, L.	PDF	N/A	Exploring the Biological Mechanisms of Severe COVID-19 in the Elderly: Insights from an Aged Mouse Model
进化独特的N-糖基依赖性蛋白质质量控制系统在新生隐球菌的细胞适应性和细胞外囊泡运输中发挥着关键作用	Mota, C.	PDF	N/A	Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
金黄色葡萄球菌酚溶性调节素介导与上呼吸道共生菌的种间竞争	Huffines, J. T.	PDF	N/A	Staphylococcus aureus Phenol-Soluble Modulins Mediate Interspecies Competition with Upper Respiratory Commensal Bacteria
细菌细胞大小沿着生长曲线在不同营养条件下进行调节	Nieto, C.	PDF	N/A	Bacterial cell size modulation along the growth curve across nutrient conditions
应用hsp60扩增子测序技术来表征与幼年及成年Euprymna scolopes乌贼相关的微生物群落	Smith, S.	PDF	N/A	Application of hsp60 amplicon sequencing to characterize microbial communities associated with juvenile and adult Euprymna scolopes squid
对近期出现的猴痘病毒分支的基因组分析揭示了与病毒毒力和传播能力改变相关的基因缺失和单核苷酸多态性。	Kumar, A.	PDF	N/A	Genomic analyses of recently emerging clades of mpox virus reveal gene deletion and single nucleotide polymorphisms that correlate with altered virulence and transmission
双转座子测序（Dual Tn-seq）用于探测全基因组范围内的遗传相互作用	Zik, J. J.	PDF	N/A	Dual transposon sequencing (Dual Tn-seq) to probe genome-wide genetic interactions
在模拟生理流动的临界摇动速度下培养疟原虫，揭示了入侵配体的新表型	Kals, E.	PDF	N/A	Growing Malaria Parasites at a Critical Shaking Speed Mimicking Physiological Flow Reveals New Phenotypes for Invasion Ligands
印度西南海岸孔卡尼人群的母系遗传亲缘关系	Sequeira, J. J.	PDF	N/A	Maternal genetic affinities of Konkani population in the southwest coast of India
使用ChemNet建模蛋白质-小分子构象集合	Anishchenko, I.	PDF	N/A	Modeling protein-small molecule conformational ensembles with ChemNet
Abdala COVID-19疫苗的结构性和功能性糖基化	Burnap, S. A.	PDF	N/A	Structural and Functional Glycosylation of the Abdala COVID-19 Vaccine
基于无监督神经网络的膀胱内窥镜图像拼接方法	Zixing, Y.	PDF	N/A	Unsupervised Neural Network-Based Image Stitching Method for Bladder Endoscopy
高通量细菌聚集分析在液滴中进行	Saar-Abroi, M.	PDF	N/A	High-throughput bacterial aggregation analysis in droplets
在表达沉默抑制因子P19和冠状病毒样颗粒的烟草本塞姆氏烟叶片中发生的分子变化	Hamel, L.-P.	PDF	N/A	Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus-like particles
成群的细菌表现出发育阶段转变，以在新区域建立分散的菌落。	Zdimal, A. M.	PDF	N/A	Swarming bacteria exhibit developmental phase transitions to establish scattered colonies in new regions
通过铜绿假单胞菌对新兴污染物在污水处理厂中的微生物降解	Lyu, B.	PDF	N/A	Microbial Degradation of Contaminants of Emerging Concern by Pseudomonas putida in Wastewater Treatment Plants
耐药菌携带者口腔微生物群的改变表现出对革兰氏阴性病原体抑制作用的受损	Zelasko, S.	PDF	N/A	Altered oral microbiota of drug-resistant organism carriers exhibit impaired gram-negative pathogen inhibition
感染性SARS-CoV-2 Omicron XBB.1.41.1谱系在圈养的白尾鹿中通过呼吸道排出，且进化速率增加	Ferreira, F. C.	PDF	N/A	Respiratory shedding of infectious SARS-CoV-2 Omicron XBB.1.41.1 lineage with increased evolutionary rate among captive white-tailed deer
蛋白质语言模型是否学习了系统发育？	Tule, S.	PDF	N/A	Do Protein Language Models Learn Phylogeny?
芳香烃受体在平滑肌细胞中的作用可保护免受二恶英诱导的动脉粥样硬化不良重塑的影响	Qin, G.	PDF	N/A	Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis
赫布诱导在发育中的海马体中，向CA3-CA1突触添加了AMPA不稳定的信号单元。	Hanse, E.	PDF	N/A	Hebbian induction adds AMPA-labile signaling units to CA3-CA1 synapses in the developing hippocampus
一种稳健且高效的转化方法，适用于最小的支原体细胞	Mizutani, M.	PDF	N/A	Robust and highly efficient transformation method for a minimal Mycoplasma cell
prfB中程序性核糖体移码的进化与功能意义	Prince, C. R.	PDF	N/A	The evolution and functional significance of the programmed ribosomal frameshift in prfB
囊性纤维化痰液中金黄色葡萄球菌生长的遗传需求和营养可用性分析	Shull, L. M.	PDF	N/A	Analysis of genetic requirements and nutrient availability for Staphylococcus aureus growth in cystic fibrosis sputum
AQP1- 与棕色脂肪组织沉默相关的调节因子	Cheng, C.	PDF	N/A	AQP1- A regulatory factor associated with brown adipose tissue silencing
参与蛋白质折叠和染色质组织的基因能够缓冲遗传变异。	Frickel, J.	PDF	N/A	Genes involved in protein folding and chromatin organization buffer genetic variation
尼安德特人衍生的变异影响人类疾病位点的颅面增强子活性	Uttley, K.	PDF	N/A	Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus
巨噬细胞在吞噬作用后重新部署功能性癌细胞表面蛋白	Volk, R. F.	PDF	N/A	Macrophages redeploy functional cancer cell surface proteins following phagocytosis
适应高压环境：从一种进化出的耐压性增强的大肠杆菌菌株的基因组中获得的见解	Allemann, M. N.	PDF	N/A	Adaptation to high pressure; insights from the genome of an evolved Escherichia coli strain with increased piezotolerance
组蛋白去甲基化酶KDM5A和KDM5B通过抑制内源性逆转录病毒元素的转录来调节免疫反应。	Chen, H.	PDF	N/A	Histone demethylase enzymes KDM5A and KDM5B modulate immune response by suppressing transcription of endogenous retroviral elements
几乎完整的人类基因组中复杂的基因变异	Logsdon, G. A.	PDF	N/A	Complex genetic variation in nearly complete human genomes
微胶质细胞与胶质母细胞瘤在远端浸润区的相互作用动力学	Nebeling, F. C.	PDF	N/A	Dynamics of microglia-glioblastoma crosstalk at the far infiltration zone
益生菌声学生物传感器用于非侵入性肠道炎症成像	Buss, M. T.	PDF	N/A	Probiotic acoustic biosensors for noninvasive imaging of gut inflammation
MedGraphNet：利用多关系图神经网络和文本知识进行生物医学预测	Macaulay, O.	PDF	N/A	MedGraphNet: Leveraging Multi-Relational Graph Neural Networks and Text Knowledge for Biomedical Predictions
吐根生物碱生物合成的独立进化	Colinas, M.	PDF	N/A	Independent evolution of ipecac alkaloid biosynthesis
从同质性到异质性：优化基因调控的随机模拟	Chae, S. J.	PDF	N/A	From Homogeneity to Heterogeneity: Refining Stochastic Simulations of Gene Regulation
神经成熟提供了表征的稳定性以及理解复杂概念的解决方案	Watanabe, H.	PDF	N/A	Neural Maturation Provides the Stability of Representation and the Solution for Understanding Complex Concepts
对小鼠端脑神经上皮顶端核迁移的定量整体活体成像分析	Shimamura, T.	PDF	N/A	Quantitative in toto live imaging analysis of apical nuclear migration in the mouse telencephalic neuroepithelium
Caveolin-1调控Ewing肉瘤中依赖于环境的信号传导和生存。	Segal, D.	PDF	N/A	Caveolin-1 regulates context-dependent signaling and survival in Ewing Sarcoma.
GDF3通过改变染色质可及性，促进脂肪组织巨噬细胞介导的炎症反应，这一过程在衰老期间尤为显著。	Jang, I. H.	PDF	N/A	GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging
ECOLOPES植物模型：一种高分辨率模型，用于模拟城市及其他人为主导和管理环境中的植物群落动态	Joschinski, J.	PDF	N/A	The ECOLOPES PLANT MODEL : a high-resolution model to simulate plant community dynamics in cities and other human-dominated and managed environments
易受伤害的驯鹿和驼鹿种群对山松甲虫爆发和管理的反应截然不同。	Griffin, L. L.	PDF	N/A	Vulnerable caribou and moose populations display contrasting responses to mountain pine beetle outbreaks and management.
古代多倍体化和染色体丢失率低解释了同型孢子蕨类植物高染色体数的原因。	Li, Z.	PDF	N/A	Ancient polyploidy and low rate of chromosome loss explain the high chromosome numbers of homosporous ferns
资源呈现方式决定了酵母的基因和表型适应性。	Ahlawat, N.	PDF	N/A	Resource presentation dictates genetic and phenotypic adaptation in yeast.
大规模死亡事件后珊瑚适应与恢复的基因组特征	Fifer, J. E.	PDF	N/A	Genomic signatures of coral adaptation and recovery following a mass mortality event
蚊子物种Culex tarsalis的气候适应与遗传分化	Liao, Y.	PDF	N/A	Climate Adaptation and Genetic Differentiation in the Mosquito Species Culex tarsalis
体外分析T7 RNA聚合酶生物传感器竞争性抑制模型的研究	Delaney, R. M.	PDF	N/A	in vitro analysis of a competitive inhibition model for T7 RNA polymerase biosensors
INSPIRE：可解释、灵活且具有空间感知能力的多种来源空间转录组数据集整合	Zhao, J.	PDF	N/A	INSPIRE: interpretable, flexible and spatially-aware integration of multiple spatial transcriptomics datasets from diverse sources
使用INMTD进行个体聚类：一种集成组学和影像数据的新型多功能多视角嵌入框架	Li, Z.	PDF	N/A	Clustering individuals using INMTD: a novel versatile multi-view embedding framework integrating omics and imaging data
RGD-含配体对整合素αVβ3分子识别的结构见解：特异性决定环（SDL）的作用	Mariasoosai, C.	PDF	N/A	Structural insights into the molecular recognition of integrin αVβ3 by RGD-containing ligands: The role of the specificity-determining loop (SDL)
类A G蛋白偶联受体（FPR2/ALX）中resolvins D1（RvD1）的进入和结合的结构基础	Mun, B.	PDF	N/A	Structural basis for the access and binding of resolvin D1 (RvD1) to formyl peptide receptor 2 (FPR2/ALX), a class A GPCR
胞外相分离介导了甲状腺球蛋白在甲状腺滤泡腔内的储存与释放	Knowles, T.	PDF	N/A	Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
IGF2BP3通过依赖M6A、独立于帽结构的c-Met翻译促进自噬介导的TNBC转移	Wang, Z.	PDF	N/A	IGF2BP3 Promotes Autophagy-Mediated TNBC Metastasis via M6A-Dependent, Cap-Independent c-Met Translation
一个优化的高通量批量RNA-Seq反卷积流程展示了肥胖和体重减轻对人类脂肪组织细胞组成的影响	Ahn, C.	PDF	N/A	An optimized pipeline for high-throughput bulk RNA-Seq deconvolution illustrates the impact of obesity and weight loss on cell composition of human adipose tissue
在小鼠骨骼肌中可诱导且可逆的SOD2敲低导致丙酮酸氧化受损和代谢灵活性降低	Ostrom, E. L.	PDF	N/A	Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility
高粱、水稻和玉米中GRAS家族转录因子结合行为的比较研究	Gladman, N. P.	PDF	N/A	GRAS Family Transcription Factor Binding Behaviors in Sorghum bicolor, Oyrza, and Maize
靶向CCRL2增强结核病小鼠模型的治疗效果	Wang, T.	PDF	N/A	Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model
穿孔素-2在宿主防御烟曲霉和白色念珠菌方面并非必需。	Aufiero, M.	PDF	N/A	Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans
从波兰患有牛呼吸道疾病症状的奶牛犊中分离出的多杀性巴氏杆菌和溶血性曼海姆菌的抗菌药物抗性及毒力相关基因	Lachowicz-Wolak, A.	PDF	N/A	Antimicrobial Resistance and Virulence-Associated Genes of Pasteurella multocida and Mannheimia haemolytica Isolated from Polish Dairy Calves with Symptoms of Bovine Respiratory Disease
对日本青鳉在不同大小片段中的环境RNA进行全面测序，并与皮肤RNA进行比较	Hiki, K.	PDF	N/A	Comprehensive Sequencing of Environmental RNA from Japanese Medaka at Various Size Fractions and Comparison with Skin RNA
对日本青鳉不同大小片段的环境RNA进行全面测序，并与皮肤RNA进行比较	Hiki, K.	PDF	N/A	Comprehensive Sequencing of Environmental RNA from Japanese Medaka at Various Size Fractions and Comparison with Skin RNA
景观分区的模式表明，几内亚狒狒（Papio papio）群体之间存在较低的资源竞争水平。	Ohrndorf, L.	PDF	N/A	Patterns of landscape partitioning indicate low levels of resource competition among neighbouring Guinea baboon(Papio papio) parties
在个人基因组和转录组数据上微调序列到表达模型	Rastogi, R.	PDF	N/A	Fine-tuning sequence-to-expression models onpersonal genome and transcriptome data
ELLA：在高分辨率空间转录组学中建模细胞内基因表达的亚细胞空间变异。	Wang, J.	PDF	N/A	ELLA: Modeling Subcellular Spatial Variation of Gene Expression within Cells in High-Resolution Spatial Transcriptomics.
机器人可见光光学相干断层扫描技术可视化了段状施莱姆管的解剖结构及段状毛果芸香碱反应	Fang, R.	PDF	N/A	Robotic Visible-Light Optical Coherence Tomography Visualizes Segmental Schlemms Canal Anatomy and Segmental Pilocarpine Response
海月：基于语言模型的分子运动预测	Lombard, V.	PDF	N/A	SeaMoon: Prediction of molecular motions based on language models
评估帕金森病中α-突触核蛋白寡聚体累积神经毒性的标准	Kuznetsov, A. V.	PDF	N/A	Criterion for assessing accumulated neurotoxicity of alpha-synuclein oligomers in Parkinson's disease
使用靶向CRISPR基因编辑技术生成对PARPi敏感的纯合BRCA1甲基化OVCAR8细胞系	Nesic, K.	PDF	N/A	Generation of a PARPi-sensitive homozygous BRCA1-methylated OVCAR8 cell line using targeted CRISPR gene editing
利用转录调控网络预测结核分枝杆菌中的细菌适应性：可解释的机器学习方法	Bustad, E.	PDF	N/A	Predicting bacterial fitness in Mycobacterium tuberculosis with transcriptional regulatory network-informed interpretable machine learning
RNA-DCGen：基于LLM-Attack的双重约束RNA序列生成	Shahgir, H. S.	PDF	N/A	RNA-DCGen: Dual Constrained RNA Sequence Generation with LLM-Attack
妊娠期SARS-CoV-2感染的胎盘中显示出氧化应激和DNA损伤的焦点。	Nobrega, G.	PDF	N/A	Placentas from SARS-CoV-2 infection during pregnancy exhibit foci of oxidative stress and DNA damage
对来自欧洲和南美洲的四种羊口疮病毒株的全基因组分析。	Cacciabue, M.	PDF	N/A	The whole genome analysis of four Orf virus strains from Europe and South America.
新型高质量阿米巴虫基因组揭示巨型病毒与其宿主之间普遍存在的密码子使用不匹配现象	Willemsen, A.	PDF	N/A	Novel high-quality amoeba genomes reveal widespread codon usage mismatch between giant viruses and their hosts
果蝇X连锁肾上腺脑白质营养不良ABCD1基因的遗传分析揭示了其在过氧化物酶体动力学中的作用	Manor, J.	PDF	N/A	Genetic analysis of the X-linked Adrenoleukodystrophy ABCD1 gene in Drosophila uncovers a role in Peroxisomal dynamics
在基因组学时代计算和解释FST	de Jong, M. J.	PDF	N/A	Calculating and interpreting FST in the genomics era
从与果蝇相关的三种螺原体（Citri 支系）菌株的草图基因组组装中推断出其毒素库多样但代谢能力有限	Ramirez, P.	PDF	N/A	Diverse toxin repertoire but limited metabolic capacities inferred from the draft genome assemblies of three Spiroplasma (Citri clade) strains associated with Drosophila
利用界面张力分选法（SIFT）逐步分离多种代谢细胞群体	Shulman, M.	PDF	N/A	Stepwise Isolation of Diverse Metabolic Cell Populations Using Sorting by Interfacial Tension (SIFT)
p53motifDB：整合基因组信息与肿瘤抑制因子p53结合基序	Baniulyte, G.	PDF	N/A	p53motifDB: integration of genomic information and tumor suppressor p53 binding motifs
SARS CoV 2核衣壳蛋白的二聚化结构域在单体状态下部分无序，并形成高亲和力的动态复合物。	Cubuk, J.	PDF	N/A	The dimerization domain of SARS CoV 2 Nucleocapsid protein is partially disordered as a monomer and forms a high affinity dynamic complex.
铜绿假单胞菌外膜胞外多糖转运蛋白PelBC的组装与动力学	Benedens, M.	PDF	N/A	Assembly and dynamics of the outer membrane exopolysaccharide transporter PelBC of Pseudomonas aeruginosa
SUMO2抑制逆转了由滑膜肉瘤融合癌蛋白驱动的异常表观遗传重编程，并损害了肉瘤发生	Iyer, R.	PDF	N/A	SUMO2 Inhibition Reverses Aberrant Epigenetic Rewiring Driven by Synovial Sarcoma Fusion Oncoproteins and Impairs Sarcomagenesis
利用深度学习技术对化石禾本科花粉的超分辨率图像进行分析，重构古草原的多样性动态变化	Adaime, M.-E.	PDF	N/A	Reconstructing the diversity dynamics of paleo-grasslands using deep learning on superresolution images of fossil Poaceae pollen
XXX和XXY三倍体大麻的性表达、生物量、大麻素含量及种子产量的比较	Paul, N.	PDF	N/A	A Comparison of the Sexual Expression, Biomass, Cannabinoid Content, and Seed Production in XXX and XXY Triploid Cannabis
用于测试抗SARS-CoV-2炎症化合物的炎症细胞平台（INCEPLAT）	LOPEZ-AYLLON, B. D.	PDF	N/A	Inflammation cellular platform (INCEPLAT) for testing anti-inflammatory compounds for SARS-CoV-2
SARS-CoV-2 ORF3a蛋白损害合胞体滋养层细胞的成熟，改变ZO-1的定位，并在滋养层细胞和三维类器官中改变自噬途径	Kumar, D.	PDF	N/A	SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids
由丙酮酸脱氢酶驱动的碳水化合物燃料的线粒体氧化作用显著增强了老年和老年期肠干细胞的干性。	Ahmed, S.	PDF	N/A	Mitochondrial oxidation of the carbohydrate fuel driven by pyruvate dehydrogenase robustly enhances stemness of older and geriatric Intestinal Stem Cells
GATA2缺乏综合征中的血液学表型源于继发性损伤和对增殖的适应不良。	Fernandez-Orth, J.	PDF	N/A	Hematological phenotypes in GATA2 deficiency syndrome arise from secondary injuries and maladaptation to proliferation
感染负荷的均值和方差揭示了未被察觉的宿主进化	Walsman, J. C.	PDF	N/A	The mean and variance of infection load reveal unseen host evolution
昆虫神经性别决定系统的演化：蟋蟀中的doublesex同源基因作为X连锁的雄性化因子，调节形态学上的性别二型性，但不影响行为上的性别二型性。	Watanabe, T.	PDF	N/A	Evolution of the neural sex-determination system in insects: The doublesex homolog in crickets functions as an X-linked masculinizing factor to regulate morphological but not behavioral sexual dimorphism
钙黏蛋白16通过斯塔尼乌斯内分泌小体促进感觉门控	Schloss, S. S.	PDF	N/A	Cadherin 16 promotes sensory gating via the endocrine corpuscles of Stannius
基于长读长全基因组测序的单细胞同时单倍型分型与非整倍体分析	Zhao, Y.	PDF	N/A	Long-read whole-genome sequencing-based concurrent haplotyping and aneuploidy profiling of single cells
伤口闭合过程中EDA纤连蛋白微结构与YAP易位的关系	Patten, J.	PDF	N/A	EDA Fibronectin Microarchitecture and YAP Translocation During Wound Closure
不同前列腺癌模型中的氧化磷酸化抑制及其与雄激素受体信号的相互作用	Sakellakis, M.	PDF	N/A	Oxidative Phosphorylation Inhibition in Different Prostate Cancer Models and the Interplay with Androgen Receptor Signaling
高维中介分析与网络中介：应用于儿童急性淋巴细胞白血病	Wang, J.	PDF	N/A	High-Dimensional Mediation Analysis with Network Mediators: Applications to Pediatric Acute Lymphoblastic Leukemia.
视觉雪花症患者的方向运动敏感性受到拖尾型视物残留存在的影响而发生调节。	Obukhova, T. S.	PDF	N/A	Directional motion sensitivity in people with Visual Snow Syndrome is modulated by the presence of trailing-type palinopsia
自闭症谱系障碍中社会视觉通路的破坏	Li, C.	PDF	N/A	Disruption of the Social Visual Pathway in Autism Spectrum Disorder
自身抗体针对干扰素在慢性乙型肝炎病毒感染者中较为常见，并与聚乙二醇干扰素治疗无应答相关。	Fink, D. L.	PDF	N/A	Auto-antibodies against interferons are common in people living with chronic hepatitis B virus infection and associate with PegIFN non-response
通用感受系统作为金黄色葡萄球菌转录组活动的新型调节器	Tetz, G.	PDF	N/A	Universal Receptive System as a novel regulator of transcriptomic activity of Staphylococcus aureus
阿尔伯塔首次记录库蚊（双翅目：蚊科）：加拿大西部省份分布范围扩大及生态型模式	Soghigian, J.	PDF	N/A	First record of Culex pipiens (Diptera: Culicidae) in Alberta: Expanding distributions and ecotype patterns in a western Canadian province
隐形人群：探究遥感数据集如何揭示森林周边人口的分布情况	Rakotoarisoa, M.	PDF	N/A	Invisible people: Exploring how well remote-sensed datasets reveal the distribution of forest-proximate populations
萤火虫Photinus pyralis中色素在光色变化中的作用	Popecki, M. S.	PDF	N/A	The role of pigments in light color variation of the firefly Photinus pyralis
通过ATAC-seq定义的足迹QTLs鉴定与转录因子结合相关的非编码变异的特征，在肝脏中的研究	Dudek, M. F.	PDF	N/A	Characterization of non-coding variants associated with transcription factor binding through ATAC-seq-defined footprint QTLs in liver
物种间连锁不平衡图谱	Zhu, T.-N.	PDF	N/A	An Atlas of Linkage Disequilibrium Across Species
Sost mRNA和Sclerostin在体内机械负荷下的三维空间分布	Meslier, Q. A.	PDF	N/A	3D spatial distribution of Sost mRNA and Sclerostin expression in response to in vivo mechanical loading
发芽糙米研究：进展、热点与趋势的文献计量分析	Zhang, W.	PDF	N/A	Germinated brown rice research: bibliometric analysis of progress, hotspots and trends
利用神经网络校正FoldX自由能估算	Barnes, J. E.	PDF	N/A	Leveraging neural networks to correct FoldX free energy estimates
nSMase2介导的外泌体分泌塑造了肿瘤微环境，以免疫学方式支持胰腺癌	Hendley, A. M.	PDF	N/A	nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer
糖饮食对蚊子湿度偏好、存活率及宿主降落的影响	Chen, S.-C.	PDF	N/A	The impact of sugar diet on humidity preference, survival, and host landing in mosquitoes
从头设计平行和反平行A3B3异源六聚体α螺旋桶	Chubb, J. J.	PDF	N/A	De novo design of parallel and antiparallel A3B3 heterohexameric alpha-helical barrels
生物系统中反馈调节的鲁棒性基本权衡	Tran, N. H. N.	PDF	N/A	Fundamental trade-offs in the robustness of biological systems with feedback regulation
分裂RNA开关：通过预翻译和翻译后调控的集合实现基因表达的可编程和精确控制	Abe, I.	PDF	N/A	Split RNA switch: Programmable and precise control of gene expression by ensemble of pre- and post-translational regulation
通过亚洲乳腺癌转录组测序检测肿瘤内微生物群	Yeo, L.-F.	PDF	N/A	Detection of intra-tumoral microbiota from transcriptomic sequencing of Asian breast cancer
肠道微生物群移植后定植失败加剧了DSS诱导的结肠炎	Gustafson, K. L.	PDF	N/A	Failure of colonization following gut microbiota transfer exacerbates DSS-induced colitis
甲型流感病毒通过细胞凋亡的启动诱导形成类似隧道纳米管的结构。	Weir, D.	PDF	N/A	Influenza A viruses induce tunnelling nanotube-like structures through the onset of apoptosis
人α-防御素中和AAV2的机制	Porter, J. M.	PDF	N/A	Mechanisms of AAV2 neutralization by human alpha-defensins
非光学、无标记的微生物电容成像技术	Incandela, J. T.	PDF	N/A	Non-Optical, Label-free Electrical Capacitance Imaging of Microorganisms
掌握纯细菌菌株对微污染物完全分解的限制：一项蛋白质组学和动力学研究	Gordillo, A. P. L.	PDF	N/A	Grasping the constraints of pure bacterial strains for the complete catabolism of micropollutants: a proteomic and kinetic study
铜绿假单胞菌LasR缺陷型突变体由于细胞内谷胱甘肽水平较低，表现出对甲基乙二醛和过氧化氢的敏感性增加。	Ruzic, M.	PDF	N/A	Pseudomonas aeruginosa LasR-deficient mutants have increased methylglyoxal and hydrogen peroxide sensitivity due to low intracellular glutathione
河流至湖泊连续体中的异养固氮作用：生活方式及其对氮气固定的贡献	Geisler, E.	PDF	N/A	Heterotrophic diazotrophy along a river to lake continuum: lifestyle and contribution to N2 fixation
耐碳青霉烯类肠杆菌霍氏菌利用黏液代谢促进胃肠道定殖	Sinha, R.	PDF	N/A	Carbapenem-Resistant Enterobacter hormaechei Uses Mucus Metabolism to Facilitate Gastrointestinal Colonization
利用动态核极化增强的固态核磁共振技术对天然细菌生物膜进行高灵敏度分析	Byeon, C.-H.	PDF	N/A	High-Sensitivity Analysis of Native Bacterial Biofilms Using Dynamic Nuclear Polarization-Enhanced Solid-State NMR
在公共蛋白质数据库中的未表征序列中，发现了数百种外源性和内源性RNA病毒RdRp序列。	Brown, K.	PDF	N/A	Uncovering hundreds of exogenous and endogenous RNA viral RdRp sequences amongst uncharacterised sequences in public protein databases
白色念珠菌和金黄色葡萄球菌相互促进致病因素的分泌。	Pasman, R.	PDF	N/A	Candida albicans and Staphylococcus aureus reciprocally promote secretion of virulence factors
鉴定出一种属于“flexivirus”相关家族的新型真菌病毒，其病毒粒子呈二十面体结构	Wu, C.-F.	PDF	N/A	Identification of a novel mycovirus belonging to the ''flexivirus''-related family with icosahedral virion
鼻腔微生物群在人类鼻腔上皮类器官中差异定植并诱导细胞因子产生	Boyd, A. I.	PDF	N/A	Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids
在虾生长的早期阶段施用钼酸盐可抑制虾池底部模型中硫化物的形成	Torun, F.	PDF	N/A	Molybdate application in the early stages of shrimp growth suppresses sulphide formation in a shrimp pond bottom model
一种用于评估正布尼亚病毒神经疾病遗传决定因素的混合搭配反向遗传系统	Miettinen, H. M.	PDF	N/A	A mix-and-match reverse genetics system for evaluating genetic determinants of orthobunyavirus neurological disease
重新审视氧毒性：超氧化物在缺乏SOD的细菌病原体中的进化与适应	Huete, S. G.	PDF	N/A	Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen
内生真菌枝孢菌BRN05的α-葡萄糖苷酶抑制活性和基于UHPLC-ESI-QTOF-MS的代谢谱分析，该菌株分离自大叶桃花心木的种子。	Kumar, P.	PDF	N/A	Elucidation of α-glucosidase inhibitory activity and UHPLC-ESI-QTOF-MS based metabolic profiling of endophytic fungi Alternaria sp. BRN05. isolated from seeds of Swietenia macrophylla King.
DNA甲基化和去甲基化驱动的脓毒症调控	Saini, A. K.	PDF	N/A	DNA methylation and demethylation driven regulation of sepsis
一个赋能基因通路发现和基因表达辅助疾病分类的图谱引导框架	Wang, Y.	PDF	N/A	A Graph Informed Framework Empowering Gene Pathway Discovery and Gene Expression-Assisted Disease Classification
通过使用具有一致N-连接糖基化抗原的HDX-MS实现糖蛋白的表位分析	Ota, T.	PDF	N/A	Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans
肌肉协同作用在神经肌肉骨骼建模中减少肌电图通道数量的初步研究	Romanato, M.	PDF	N/A	Muscle synergies to reduce the number of electromyography channels in neuromusculoskeletal modelling: a pilot study
varCADD：大量现有的遗传变异数据能够实现全基因组致病性预测	Nazaretyan, L.	PDF	N/A	varCADD: large sets of standing genetic variation enable genome-wide pathogenicity prediction
III型CRISPR-Cas位点中的环状核酸酶的多样性和丰度	Hoikkala, V.	PDF	N/A	Diversity and abundance of ring nucleases in type III CRISPR-Cas loci
乳腺癌球体偏好活化的巨噬细胞作为共犯：一项体外研究	Teli, A.	PDF	N/A	Breast cancer spheroids prefer activated macrophages as an accomplice: An in vitro study
多发性硬化症皮质中β淀粉样蛋白减少和神经原纤维缠结减少的神经病理学证据	Pansieri, J.	PDF	N/A	Neuropathological evidence of reduced amyloid beta and neurofibrillary tangles in multiple sclerosis cortex
利用工程环境细菌降解PET塑料	Banks, A. M.	PDF	N/A	Degradation of PET plastic with engineered environmental bacteria
真核生物可编程基因表达的正交转录引擎的定向进化	Kar, S.	PDF	N/A	Directed evolution of an orthogonal transcription engine for programmable gene expression in eukaryotes
信号序列将酶和结构蛋白靶向细菌微区室，对微区室的形成至关重要。	Johnson, E. R.	PDF	N/A	Signal sequences target enzymes and structural proteins to bacterial microcompartments and are critical for microcompartment formation
鸟类干扰素调节因子（IRF）家族团聚：IRF3与IRF9相聚	Ungrova, L.	PDF	N/A	Avian interferon regulatory factor (IRF) family reunion: IRF3 and IRF9 found
SbcB 以不依赖核酸外切酶的方式促进霍乱弧菌的自然转化	Dalia, T. N.	PDF	N/A	SbcB facilitates natural transformation in Vibrio cholerae in an exonuclease-independent manner
完整细菌鞭毛的细胞外结构揭示了鞭毛蛋白插入的机制	Einenkel, R.	PDF	N/A	Structure of the complete extracellular bacterial flagellum reveals mechanism for flagellin incorporation
培养的肺泡基底细胞显示出与气道基底细胞相似的特征和功能特性。	Blumer, S.	PDF	N/A	Cultured alveolar basal cells display similar characteristics and functional properties to airway basal cells
人类GPR155的冷冻电镜结构揭示了其调控和转运机制	Sharma, M.	PDF	N/A	Cryo-EM structures of human GPR155 elucidate its regulatory and transport mechanisms
# BioRxiv 2024-09-24 Papers

标题	作者	PDF链接	代码仓库	Title
内吞循环在昼夜节律性胶原蛋白纤维形成中起核心作用，并在纤维化过程中受到破坏。	CHANG, J.	PDF	N/A	Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis
Rab10失活促进AMPAR插入和树突棘增大在长时程增强过程中	Wang, J.	PDF	N/A	Rab10 inactivation promotes AMPAR insertion and spine enlargement during long-term potentiation
基于CRISPR-Cas的微同源介导的末端连接用于植物中精确基因替换	Vu, T. V.	PDF	N/A	CRISPR-Cas-based Microhomology-Mediated End Joining for Precise Gene Replacement in Plant
已撤回：拟南芥三羧酸循环中涉及的调控蛋白质的计算机分析及通过Alphafold和其他软件进行的结构分析	Nayab, H.	PDF	N/A	WITHDRAWN: In-silico analysis of regulatory proteins involved in tricarboxylic acid cycle of Arabidopsis thaliana and structural analysis by Alphafold and other software
热循环-高温下调了脂多糖诱导的人血炎症，并有助于清除单纯疱疹病毒1型	Kuo, Y.-Y.	PDF	N/A	Thermal cycling-hyperthermia down-regulates liposaccharide-induced inflammation in human blood and helps with clearance of herpes simplex virus type 1
脑细胞外基质中的硫酸化糖胺聚糖取代了细胞外氯离子	Normoyle, K. P.	PDF	N/A	Displacement of extracellular chloride by sulfated glycosaminoglycans of the brain extracellular matrix
中度元基因组学：一种从环境样本中无需培养即可重建微生物基因组的新方法	Vollmers, J.	PDF	N/A	Midi-metagenomics: A novel approach for cultivation independent microbial genome reconstruction from environmental samples
Hsf1-sHsp级联在蚊子细胞中具有广谱抗病毒活性	Qu, J.	PDF	N/A	The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells
鞭毛开关反向重复序列影响鞭毛的可逆性，并因梭状芽孢杆菌RT027/MLST1的毒力而异。	Nhu, N. T. Q.	PDF	N/A	Flagellar switch inverted repeat impacts flagellar invertibility and varies Clostridioides difficile RT027/MLST1 virulence.
对费氏弧菌中环二鸟苷酸调节蛋白的功能分析	Isenberg, R. Y.	PDF	N/A	Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri
突变顺序和上位性决定了FBXW7突变在结直肠癌进化中的后果	Chan, D. K. H.	PDF	N/A	Mutational order and epistasis determine the consequences of FBXW7 mutations during colorectal cancer evolution
双路径架构使慢性压力能够破坏自主性并促进习惯的形成。	Giovanniello, J. R.	PDF	N/A	A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation
硅藻CO2固定器官的蛋白质蓝图	Nam, O.	PDF	N/A	A Protein Blueprint of the Diatom CO2-Fixing Organelle
在剪接泛基因组图上对选择性剪接事件进行差异定量	Ciccolella, S.	PDF	N/A	Differential quantification of alternative splicing events on spliced pangenome graphs
心脏交感和副交感指数的稳健且时间分辨的估计	Candia-Rivera, D.	PDF	N/A	Robust and time-resolved estimation of cardiac sympathetic and parasympathetic indices
水平转移的无细胞染色质颗粒在宿主细胞内作为自主捕食性基因组和转座元件的载体发挥作用。	Banerjee, S.	PDF	N/A	Horizontally transferred cell-free chromatin particles function as autonomous predatory genomes and vehicles for transposable elements within host cells
RomX是一种新型原核调节因子，它将RomR的响应接收域与GTP结合的MglA连接起来，以建立Myxococcus xanthus的极性。	Chakraborty, S.	PDF	N/A	RomX, a novel prokaryotic regulator, links the response receiver domain of RomR with GTP-bound MglA for establishing Myxococcus xanthus polarity
大声朗读与默读过程中信息权重的差异：基于fMRI数据表征相似性分析的证据	Bailey, L. M.	PDF	N/A	Differential weighting of information during aloud and silent reading: Evidence from representational similarity analysis of fMRI data
CPT1A在结直肠癌中调节辐射敏感性	Chen, Z.	PDF	N/A	CPT1A Mediates Radiation Sensitivity in Colorectal Cancer
盐诱导的根冠比自然变异揭示SR3G为拟南芥根栓化及盐韧性的负调控因子	Ishka, M. R.	PDF	N/A	Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis
学习从快速手动点注释中精确分割神经纤维缠结	Ghandian, S.	PDF	N/A	Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations
在生长表面上超无序的细胞排列	Ross, R. J. H.	PDF	N/A	Hyperdisordered cell packing on a growing surface
利用基因组数据预测的气候适宜性比较加利福尼亚海峡群岛橡树（Quercus tomentella）的保护策略	Mead, A.	PDF	N/A	Comparison of conservation strategies for California Channel Island Oak (Quercus tomentella) using climate suitability predicted from genomic data
定义肺癌细胞对表观遗传抑制反应的异质分子图谱	Lin, C.	PDF	N/A	Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition
在铜绿假单胞菌临床分离株中，前噬菌体与抗生素耐药性的关联并不常见。	Chang, T. H.	PDF	N/A	Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates
在铜绿假单胞菌临床分离株中，前噬菌体与抗生素耐药性的关联并不常见。	Chang, T. H.	PDF	N/A	Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates
清洁死者：优化的去污方法提升更新世骨骼材料的古蛋白质组学分析效果	Fagernäs, Z.	PDF	N/A	Cleaning the Dead: Optimized decontamination enhances palaeoproteomic analyses of Pleistocene skeletal material
空间转录组学鉴定出新型铜绿假单胞菌毒力因子	Zhou, H.	PDF	N/A	Spatial transcriptomics identifies novel Pseudomonas aeruginosa virulence factors
遗传逻辑电路的能量感知技术映射	Kubaczka, E.	PDF	N/A	Energy Aware Technology Mapping of Genetic Logic Circuits
小鼠GnRH神经元在体内的多维振荡活动	Han, S. Y.	PDF	N/A	Multi-dimensional oscillatory activity of mouse GnRH neurons in vivo
斑马鱼HoxA和HoxD相关簇在胸鳍发育中的功能作用	Ishizaka, M.	PDF	N/A	The functional roles of zebrafish HoxA- and HoxD-related clusters in the pectoral fin development
质粒病毒维持能够使细菌种群从感染中恢复，并实现病毒与细菌的共存。	Sanchez-Martinez, R.	PDF	N/A	Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence
有毒的蓝光通过驱动肠道微生物介导的脂质积累，在果蝇中建立耐受性	Takada, Y.	PDF	N/A	Toxic blue light drives the gut microbiota-mediated lipid accumulation to build tolerance in Drosophila
功能成像和连接组分析揭示了果蝇味觉回路的组织原理	Li, J.	PDF	N/A	Functional imaging and connectome analyses reveal organizing principles of taste circuits in Drosophila
评估生理指标在通过比较问题测试（CQT）检测欺骗和诚实性中的应用	Rashid, A. M. S.	PDF	N/A	Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT)
评估生理指标在通过比较问题测试（CQT）检测欺骗和真实性中的应用	Rashid, A. M. S.	PDF	N/A	Evaluating Physiological Indicators in Detecting Deception and Truthfulness using the Comparison Question Test (CQT)
一种生理学启发的混合CPG/反射控制器，用于自行车模拟，并可推广至步行	Severini, G.	PDF	N/A	A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking
癌症-免疫共进化由抗原突变积累所决定	Wang, L.	PDF	N/A	Cancer-immune coevolution dictated by antigenic mutation accumulation
豆科植物共生基因的突变在多菌株接种过程中为根瘤菌的自然遗传变异创造了一个复杂的选择性环境。	Guha, S.	PDF	N/A	Mutations in legume symbiosis genes create a complex selective landscape for natural genetic variation in rhizobia during multi-strain inoculations
AyurPhenoClusters 定义了罕见疾病的共同分子根源，并揭示了综合征条件下纤毛功能障碍。	Joshi, A.	PDF	N/A	AyurPhenoClusters define common molecular roots for rare diseases and uncover ciliary dysfunctions in syndromic conditions
灵长类新皮层中是否存在普遍的局部场电位功率频谱层状模式？	Mackey, C. A.	PDF	N/A	Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex?
通过基于CRISPR/Cas9 RNP的植物体内基因编辑技术培育出的长保质期甜瓜	Sasaki, K.	PDF	N/A	A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing
液滴测序揭示口腔生物膜外泌体中的毒力基因簇	Takano, S.	PDF	N/A	Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles
GWA-X：一个可扩展的GPU加速包，用于全基因组关联研究中的排列检验	Agung, M.	PDF	N/A	GWA-X: An Extensible GPU Accelerated Package for Permutation Testing in Genome-Wide Association Studies
泛基因组启发的语言模型用于隐私保护的合成基因组序列生成	Huang, P.	PDF	N/A	Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation
海马体γCaMKII的多巴胺化促进突触到核的信号传递及记忆形成	Stewart, A. F.	PDF	N/A	Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation
外生菌根真菌松乳菇（Suillus luteus）在原生和引入种群中的生物合成基因簇多样性	Allen, B. M.	PDF	N/A	Biosynthetic Gene Cluster Diversity Across Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus
GCK-MODY中独特的持续时间和饮食依赖性脂质谱及肾并发症	Huang, Y.	PDF	N/A	Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
造血干细胞来源的脂肪细胞消融减少了同基因小鼠高级别浆液性癌模型中的肿瘤负荷	Woodruff, E. R.	PDF	N/A	Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma
利用光遗传学技术快速可逆地调控出芽酵母细胞周期的进展	Koutsoumpa, A.	PDF	N/A	Rapid and reversible regulation of cell cycle progression in budding yeast using optogenetics
胆碱能神经元活性通过毒蕈碱信号传导促进弥漫性中线胶质瘤的生长	Drexler, R.	PDF	N/A	Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling
膜相关传送带控制细菌第9型分泌系统的旋转方向	Trivedi, A.	PDF	N/A	A membrane-associated conveyor belt controls the rotational direction of the bacterial type 9 secretion system
量化生物研究中条形图的数据失真	Lin, T.-J.	PDF	N/A	Quantifying Data Distortion in Bar Graphs in Biological Research
人类肺部先天性和适应性免疫细胞的动态反应突显了哮喘风险位点基因的作用	Tian, F.	PDF	N/A	Dynamic responses of human lung innate and adaptive immune cells highlight the roles of genes at asthma risk loci
在受控的人类流感病毒感染后，先天免疫的表观基因组景观	Thistlethwaite, W.	PDF	N/A	Innate immune epigenomic landscape following controlled human influenza virus infection
加尔瓦宁是一种用于定向细胞迁移的电场传感器。	Belliveau, N. M.	PDF	N/A	Galvanin is an electric-field sensor for directed cell migration
果蝇发育翅膀中立方上皮向扁平上皮转变的机械调控	Harmansa, S.	PDF	N/A	Mechanical regulation of cuboidal-to-squamous epithelial transition in the Drosophila developing wing
Elavl1对于附肢骨骼发育并非必需。	Parsha, R.	PDF	N/A	Elavl1 is dispensable for appendicular skeletal development
PAEP、KRT10和BMP7基因SNPs与克莱猪繁殖性状的关联分析	Zhao, Y.	PDF	N/A	Association analysis of PAEP, KRT10 and BMP7 Genes SNPs with reproductive traits in Kele pigs
保护基因组研究中的隐私：作者全面框架	Ghasemian, M.	PDF	N/A	Safeguarding Privacy in Genome Research: A Comprehensive Framework for Authors
基于网络药理学、分子对接及细胞实验探讨滋癸益冲方减轻卵巢早衰中卵泡颗粒细胞凋亡的机制	Zhang, X.	PDF	N/A	Explore the mechanism of Zigui Yichong Formula in reducing the apoptosis of ovarian granulosa cells in premature ovarian insufficiency based on network pharmacology, molecular docking and cell experiments
构建儿童科学绘画的规范：基于大语言模型语义相似性的分布特征	Zhang, Y.	PDF	N/A	Constructing a Norm for Children's Scientific Drawing: Distribution Features Based on Semantic Similarity of Large Language Models
探究视觉素养技能揭示了学生对染色体尺度与抽象概念的理解。	Uminski, C.	PDF	N/A	Probing visual literacy skills reveals student conceptions of scale and abstraction with respect to chromosomes
丙酮酸的命运通过调节细胞的氧化还原电位来决定细胞的生长。	Toshniwal, A. G.	PDF	N/A	The fate of pyruvate dictates cell growth by modulating cellular redox potential
表面递送定量揭示了成簇的protocadherin异构体之间不同的运输效率	May, E. J.	PDF	N/A	Surface delivery quantification reveals distinct trafficking efficiencies among clustered protocadherin isoforms
振动幅度在红眼树蛙胚胎逃逸孵化反应中的作用	Jung, J.	PDF	N/A	The role of vibration amplitude in the escape hatching response of red-eyed treefrog embryos
erm-1的本地化翻译有助于ERM-1在秀丽隐杆线虫胚胎中的功能	Salm, E. v. d.	PDF	N/A	Localized translation of erm-1 contributes to ERM-1 function in the C. elegans embryo
高WEE1表达与多发性骨髓瘤患者的不良生存率独立相关。	Simhal, A. K.	PDF	N/A	High WEE1 expression is independently linked to poor survival in multiple myeloma
早期阿尔茨海默病中突触密度与代谢型谷氨酸受体之间关系的评估：一项多示踪剂PET研究	Salardini, E.	PDF	N/A	Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer's disease: a multi-tracer PET study
发酵底物的分解代谢性质影响无氧生长下大肠杆菌的蛋白质组重构	Momin, H.	PDF	N/A	The catabolic nature of fermentative substrates influence proteomic rewiring in Escherichia coli under anoxic growth
通过表征VGLUT1mEos2敲低的新型小鼠模型，揭示了VGLUT1表达水平对量子大小的一个微小影响。	Zhang, X. M.	PDF	N/A	A minor impact of VGLUT1 expression level on quantal size revealed through the characterization of VGLUT1mEos2 knock-down new mouse model
脊髓损伤引起的脑部炎症和认知能力下降可以通过脊髓细胞移植得到逆转。	Delarue, Q.	PDF	N/A	Brain inflammation and cognitive decline induced by spinal cord injury can be reversed by spinal cord cell transplants
小鼠上丘视觉表征的扫视调制神经基质	Hunt, J.	PDF	N/A	Neural substrates for saccadic modulation of visual representations in mouse superior colliculus
绿色合成氧化铁/石墨烯磁性纳米复合材料作为新型抗菌材料的制备	Kazazi, M.	PDF	N/A	Production of green synthesized iron oxide/graphene magnetic nanocomposite as a novel antibacterial material
环境泥炭藓相关真菌通过靶向硫醇稳态与结核分枝杆菌竞争。	Malhotra, N.	PDF	N/A	Environmental sphagnum-associated fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.
利用背腹侧亨廷顿病类器官和亨廷顿病小鼠胚胎鉴定幼年亨廷顿病细胞群体的神经发育组织	Switonska-Kurkowska, K.	PDF	N/A	Identification of neurodevelopmental organization of the cell populations of juvenile Huntington's disease using dorso-ventral HD organoids and HD mouse embryos
埃及伊蚊中肠提取物的全面蛋白水解分析：揭示血液餐蛋白消化系统	O'Donoghue, A. J.	PDF	N/A	Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system
胎儿特异性基因LIN28B对人类胎儿B淋巴细胞生成至关重要，并参与KMT2A::AFF1婴儿白血病的启动。	Ling, R. E.	PDF	N/A	The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia
H9c2分化的优化导致无需添加视黄酸即可形成钙活性及横纹肌心脏细胞。	Brock, J.	PDF	N/A	Optimization of H9c2 differentiation leads to calcium-active and striated cardiac cells without addition of retinoic acid.
habtools：一个用于计算表面和物体三维指标的R包	Schiettekatte, N. M.	PDF	N/A	habtools: an R package to calculate 3D metrics for surfaces and objects
一种用于检测陆地动物环境DNA的地面表面滚动方法	Kakita, M.	PDF	N/A	A ground surface rolling method for detecting environmental DNA of terrestrial animals
在考虑父亲精子储存的情况下，没有证据表明父亲的年龄对儿子或女儿有影响。	Sanghvi, K.	PDF	N/A	No evidence for paternal age effects on sons or daughters, when accounting for paternal sperm storage
野外采集的伊蚊中自然存在的沃尔巴克氏菌的全球流行率：一项系统综述和荟萃分析	Gebremariam, T. T.	PDF	N/A	Global prevalence of naturally occurring Wolbachia in field-collected Aedes mosquitoes: a systematic review and meta-analysis
与心血管疾病相关的非编码变异破坏了GATA4-DNA结合及其调控功能	Pena-Martinez, E. G.	PDF	N/A	Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions
原位通用正交网络（UNION）生物墨水沉积技术用于直接输送角膜基质干细胞至角膜伤口	Brunel, L. G.	PDF	N/A	In Situ UNIversal Orthogonal Network (UNION) Bioink Deposition for Direct Delivery of Corneal Stromal Stem Cells to Corneal Wounds
将3D打印机用作绘图仪，为进行二维迁移分析开辟了一个全新的领域。	Köppe, H.	PDF	N/A	The use of 3D-printers as plotters opens up a new world in performing 2D migration analyses
假马齿苋植物化学物质作为阿尔茨海默病治疗中有前景的BACE1抑制剂	Sangeet, S.	PDF	N/A	Bacopa monnieri phytochemicals as promising BACE1 inhibitors for Alzheimers Disease Therapy
对于脊椎动物胚胎发育而言，基因表达谱的PCA（主成分分析）解释性不如慷慨性。	Ogata, N.	PDF	N/A	Liberality is More Explainable than PCA of Transcriptome for Vertebrate Embryo Development
IκBζ的组成性表达促进黑色素瘤的生长并导致免疫疗法抵抗	Kolb, A.	PDF	N/A	Constitutive expression of IκBζ promotes tumor growth and immunotherapy resistance in melanoma
使用DARPin选择性靶向TBXT可识别脊索瘤中的调控网络和治疗脆弱性	Umbaugh, C. S.	PDF	N/A	Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma
miR-21：一种在高脂饮食小鼠中延缓重度肝病和肝细胞癌的治疗靶点	Jagtap, U.	PDF	N/A	miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice
Rho/MRTF抑制诱导的黑色素瘤细胞凋亡事件及其对药物耐药性的预防机制探讨：涉及pirin的潜在作用	Foda, B.	PDF	N/A	Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: Implications for the involvement of pirin
C57BL/6J小鼠在家庭笼中的乙醇饮用和操作性自我给药中的性别差异，但由谷氨酸AMPAR活性进行的调节是等效的。	Faccidomo, S.	PDF	N/A	Sex Differences in Home-Cage Ethanol Drinking and Operant Self-Administration in C57BL/6J Mice but Equivalent Regulation by Glutamate AMPAR Activity
在阿尔茨海默病3xTg小鼠模型中，许多热量限制的好处需要禁食才能实现。	Babygirija, R.	PDF	N/A	Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer&aposs disease
不同浓度吲哚乙酸（IAA）对不同李（Prunus domestica L.）栽培品种形态特征的响应	Ullah, K.	PDF	N/A	Response of Various Concentrations of Indole Acetic Acid (IAA) to Morphological Attributes in Different Plum (Prunus domestica L.) Curltivars
肝脏中一种矛盾的肿瘤抗原特异性反应	Trehan, R. S.	PDF	N/A	A Paradoxical Tumor Antigen Specific Response in the Liver
用于评估恒河猴支气管肺泡灌洗液中白细胞的细胞和功能表型的42参数质谱流式细胞术面板	Makatsa, M. S.	PDF	N/A	42-parameter mass cytometry panel to assess cellular and functional phenotypes of leukocytes in bronchoalveolar lavage of Rhesus macaque
可变大小群体中一般家谱的TMRCA	Wemces, A. H.	PDF	N/A	The TMRCA of general genealogies in populations of variable size
下一代雪豹种群评估工具：用于从粪便中个体识别的多重PCR SNP面板	Solari, K. A.	PDF	N/A	Next-generation snow leopard population assessment tool: multiplex-PCR SNP panel for individual identification from feces
桥本甲状腺炎背景下甲状腺乳头状癌的蛋白质组学分析	Zhou, H.	PDF	N/A	Proteomic analysis of papillary thyroid carcinoma in the context of Hashimoto's thyroiditis
学习增强型草图绘制技术在保护隐私和安全的基因组关联分析（GWAS）中提供了改进的性能。	Xu, J.	PDF	N/A	Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS
结构解析：脯氨酸富集区域在Tau功能中的作用	Acosta, K.	PDF	N/A	Structural Insights into the Role of the Proline Rich Region in Tau Function
基于机器学习的癌症及转移中整合素表达模式研究	Shadman, H.	PDF	N/A	A Machine Learning-Based Investigation of Integrin Expression Patterns in Cancer and Metastasis
在衰老的狒狒中，前额叶皮层线粒体生物能量学的性别特异性下降与行走速度相关	Adekunbi, D. A.	PDF	N/A	Sex-specific decline in prefrontal cortex mitochondrial bioenergetics in aging baboons correlates with walking speed
成纤维细胞的空间编程通过排除免疫细胞促进组织炎症的消退	Reis Nisa, P.	PDF	N/A	Spatial programming of fibroblasts promotes resolution of tissue inflammation through immune cell exclusion
MDA5 ISGylation 对免疫信号传导至关重要，可调控病毒复制和发病机制	Sarkar, L.	PDF	N/A	MDA5 ISGylation is crucial for immune signaling to control viral replication and pathogenesis
胞外cGAMP及其类似物对T细胞的毒性是由于SLC7A1介导的导入所致。	Sudaryo, V.	PDF	N/A	Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import
独立的鸟类表观遗传时钟用于衰老和发育	Haller, A.	PDF	N/A	Independent avian epigenetic clocks for aging and development
切尔诺贝利啮齿动物中代谢率与放射性剂量率的协变关系	Boratynski, Z.	PDF	N/A	Covariation between metabolic and radioactive dose rates in Chornobyl rodents
森林转化为农业用地降低了我国西南岩溶石漠化地区土壤黑碳组分含量。	Zhang, D.	PDF	N/A	The conversion of forests to agricultural land reduced the content of soil black carbon fractions in a karst rocky desertification area of Southwest China
拟除虫菊酯类杀虫剂是否会影响敏捷蛙（Rana dalmatina）的性别比例？	Balogh, E.	PDF	N/A	Do pyrethroid insecticides influence sex ratios in agile frogs (Rana dalmatina)?
热带森林中相邻生境的真菌群落时空动态和组装过程存在差异	Lin, C.-P.	PDF	N/A	Spatiotemporal dynamics and assembly process differ in fungal communities across contiguous habitats in tropical forests
蚜虫宿主转换的触发因素及决定机制解析	Etier, A.	PDF	N/A	Insights into the triggering factors and determination mechanisms of host alternation in aphids
有限种群结构但存在近期选择信号：引入北美洲的非洲无花果蝇（Zaprionus indianus）	Erickson, P. A.	PDF	N/A	Limited population structure but signals of recent selection in introduced African Fig Fly (Zaprionus indianus) in North America
南美慈鲷鳍骨的可塑性受觅食方式改变的影响	Gilbert, M.	PDF	N/A	Plasticity in the pectoral fin skeleton is induced by altered foraging regime in a South American cichlid
建立一个全球地下动物条形码参考库	Guzik, M. T.	PDF	N/A	Towards a global barcode reference library for subterranean fauna
同义突变和单核苷酸变化有助于水平转移基因的适应性。	Venkataraman, P.	PDF	N/A	Synonymous and single nucleotide changes facilitate the adaptation of a horizontally transferred gene.
古老的倒位多态性在一种广泛分布的蝴蝶物种中具有局部适应性。	Seixas, F. A.	PDF	N/A	Ancient inversion polymorphisms are locally adaptive in a widespread butterfly species
性状依赖的生物地理学为梅桂（番荔枝科）在澳大拉西亚-太平洋地区的扩散提供了见解	Liu, M.-F.	PDF	N/A	Trait-dependent biogeography offers insights on the dispersal of Meiogyne (Annonaceae) across the Australasia-Pacific region
在按蚊细胞中进行的全基因组CRISPR筛选鉴定了必需基因和氯膦酸盐脂质体功能所需的成分	Mameli, E.	PDF	N/A	A genome-wide CRISPR screen in Anopheles mosquito cells identifies essential genes and required components of clodronate liposome function
种系丢失减少了体细胞线粒体，但在衰老和低温过程中保留了呼吸功能。	Hwang, H.	PDF	N/A	Germline loss diminishes somatic mitochondria but confers preservation of respiratory function during aging and hypothermia
生物银行规模和分布式数据集中SNP遗传力的分析和计算解决方案	Qi, G.-A.	PDF	N/A	Analytical and computational solution for the estimation of SNP-heritability in biobank-scale and distributed datasets
精心挑选的转录组数据集，用于研究病毒呼吸道接种和疫苗接种后血液和鼻样本的转录反应	Lan, Z.	PDF	N/A	A curated collection of transcriptome datasets to study the transcriptional response in blood and nasal samples following viral respiratory inoculation and vaccination
高拷贝数子宫内膜癌中超倍体基因型的功能影响	Florio, A.	PDF	N/A	Functional impact of the hyperduplication genomophenotype in high copy number endometrial cancer
从头组装和注释飞虱线粒体基因组	Molligan, J.	PDF	N/A	De novo assembly and annotation of the Empoasca fabae mitochondrial genome
从斑点到细胞：使用BOMS在空间转录组学中进行细胞分割	Kamboj, O.	PDF	N/A	From spots to cells: Cell segmentation in spatial transcriptomics with BOMS
面对不断变化的海域，关键沿海生物扰动者Hediste diversicolor的分子武器库	Beine, K.	PDF	N/A	The molecular arsenal of the key coastal bioturbator Hediste diversicolor faced with changing oceans
机器学习优化的选择性剪接靶向检测	Yang, K.	PDF	N/A	Machine learning-optimized targeted detection of alternative splicing
转座元件在自然界中普遍作为跨代表观遗传继承的载体	Baduel, P.	PDF	N/A	Transposable elements are prevalent vectors of transgenerational epigenetic inheritance in nature
在严格一夫多妻制的木蚁物种中，超级基因的丧失	Sigeman, H.	PDF	N/A	The loss of a supergene in obligately polygynous Formica wood ant species
已建立的硫肽串联质谱行为和硫酸转移酶测定法否定了酪氨酸硫酸化作为组蛋白标记的可能性	Youssef, M. M.	PDF	N/A	Established Sulfopeptide Tandem Mass Spectrometry Behavior and Sulfotransferase Assays Refute Tyrosine Sulfation as a Histone Mark
直接且超灵敏的生物发光检测完整呼吸道病毒	Grawe, A.	PDF	N/A	Direct and ultrasensitive bioluminescent detection of intact respiratory viruses
AlphaFold3在抗体和纳米抗体对接方面学到了什么，还有哪些问题尚未解决？	Hitawala, F. N.	PDF	N/A	What has AlphaFold3 learned about antibody and nanobody docking, and what remains unsolved?
snCED-seq：用于FFPE组织单核RNA测序的高保真冷冻酶解离核技术	yunxia, G.	PDF	N/A	snCED-seq: High-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues
通过海洋甲烷氧化菌-微藻共培养生产依克多因，实现了生物气的完全价值化。	Ruiz-Ruiz, P.	PDF	N/A	Ectoine production through a marine methanotroph-microalgae culture allows complete biogas valorization
细菌谱系中脯氨酰寡肽酶及相关序列的鉴定与研究	Nayak, S. D.	PDF	N/A	Identification and study of Prolyl Oligopeptidases and related sequences in bacterial lineages
通过结合与对称性相关的分子来提高姿态预测的准确性	Vijayan, D.	PDF	N/A	Improving the accuracy of pose prediction by incorporating symmetry-related molecules
子宫内膜异位症中焦亡相关基因的鉴定与诊断潜力：一项新颖的生物信息学分析	Teng, P.	PDF	N/A	Identification and Diagnostic Potential of Pyroptosis-Related Genes in Endometriosis: A Novel Bioinformatics Analysis
通过综合计算机方法鉴定隐孢子虫肌苷5'-单磷酸脱氢酶的潜在抑制剂	Al-Mamun, A.	PDF	N/A	Identification of potential inhibitors against Inosine 5'-Monophosphate Dehydrogenase of Cryptosporidium parvum through an integrated in silico approach
在单细胞RNA测序中，利用scPCA联合建模细胞异质性和条件效应	Vohringer, H. S.	PDF	N/A	Joint Modeling of Cellular Heterogeneity and Condition Effects with scPCA in Single-Cell RNA-Seq
设计具有所需熔化温度的热稳定蛋白质	Tijare, P.	PDF	N/A	Designing of thermostable proteins with a desired melting temperature
探索中肠表达动力学：成年雌性美洲钝眼蜱中肠的纵向转录组分析及与其他硬蜱物种的比较见解	Lu, S.	PDF	N/A	Exploring midgut expression dynamics: longitudinal transcriptomic analysis of adult female Amblyomma americanum midgut and comparative insights with other hard tick species
解码蛋白质动力学：ProFlex作为正常模式分析中的语言桥梁	Magill, D.	PDF	N/A	Decoding Protein Dynamics: ProFlex as a Linguistic Bridge in Normal Mode Analysis
代谢建模揭示了拟南芥热生长反应的决定因素	Wendering, P.	PDF	N/A	Metabolic modeling identifies determinants of thermal growth responses in Arabidopsis thaliana
MolAR：用Rust编写的MD模拟分析内存安全库	Yesylevskyy, S.	PDF	N/A	MolAR: memory-safe library for analysis of MD simulations written in Rust
基于Martini的酶粗粒化模型的框架：模型开发与实验验证	Hooten, M.	PDF	N/A	Framework for Martini-based Coarse-grained Model of Enzymes: Model Development and Experimental Validation
老化大鼠模型中与认知相关的蛋白质结构变化与减少的重折叠能力有关	Tarbox, H. E.	PDF	N/A	Cognition-Associated Protein Structural Changes in a Rat Model of Aging are Related to Reduced Refolding Capacity
纤维蛋白凝块的介观模拟：凝胶点处流变学与微观结构的相互作用	Zohravi, E.	PDF	N/A	Mesoscale Modelling of Fibrin Clots: The Interplay between Rheology and Microstructure at the Gel Point
流动状态下二元混合物中的主动分离	Di Dio, G.	PDF	N/A	Active segregation in binary mixtures under flow
一种开放量子系统方法用于Bicoid梯度动力学	Lone, I.	PDF	N/A	An Open Quantum System Approach to Bicoid Gradient Dynamics
ATP合酶亚基e（ATP5I）在介导双胍类药物的代谢和抗增殖效应中的作用	Lefrancois, G.	PDF	N/A	The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Biguanides
食管腺癌与正常邻近组织间蛋白质表达的比较分析	Nicholas, B.	PDF	N/A	Comparative analysis of protein expression between oesophageal adenocarcinoma and normal adjacent tissue
北美野生河狸（Castor canadensis）的尸检结果揭示了对加利福尼亚淡水生态系统的潜在威胁	Gonzales-Viera, O. A.	PDF	N/A	Postmortem findings of free-ranging North American beavers (Castor canadensis) reveal potential threats to California freshwater ecosystems
通过疾病相关微生物群重新审视葡萄藤酸腐病：三重共感染？	Hevin, S.	PDF	N/A	Revisiting sour rot of grapevine through disease-associated microbiomes: a tripartite co-infection?
通过行为分析进行毒性测试，观察有机溶剂对秀丽隐杆线虫的普遍和特定不良影响	Tomioka, M.	PDF	N/A	Observation of general and specific adverse effects of organic solvents on Caenorhabditis elegans by toxicity testing using behavioral analysis
刺激调制稳态法：事件相关功能磁共振成像的新范式。	Mathew, R.	PDF	N/A	Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI.
肿瘤诱导的内皮细胞RhoA激活介导肿瘤细胞跨内皮迁移和转移	Sajib, M. S.	PDF	N/A	Tumor-induced endothelial RhoA activation mediates tumor cell transendothelial migration and metastasis
在Cyp17a1敲除大鼠中，从内脏脂肪向皮下脂肪的转变阻止了代谢综合征的进展	Jeon, B.-J.	PDF	N/A	Shift from visceral to subcutaneous fat in Cyp17a1 knockout rats prevent the progression of metabolic syndrome
ALMS1 KO大鼠：一种具有自发性高血压的新型代谢综合征模型	Jaykumar, A. B.	PDF	N/A	ALMS1 KO rat: a new model of metabolic syndrome with spontaneous hypertension
小鼠在二氧化碳挑战下的血管反应	Yang, X.	PDF	N/A	Vascular responses of hypercapnia challenge in mice
高光谱成像在遥感山毛榉树皮病初期方面能力有限。	Tougas, G.	PDF	N/A	Hyperspectral imaging has a limited ability to remotely sense the onset of beech bark disease
高阶和分布式协同功能相互作用在目标导向学习中编码信息增益	Combrisson, E.	PDF	N/A	Higher-order and distributed synergistic functional interactions encode information gain in goal-directed learning
人类和小鼠神经元皮层可分离性的内在特征识别	Yun, Z.	PDF	N/A	Identification of Intrinsic Features for Cortical Separability of Human and Mouse Neurons
前额叶皮层中视觉运动神经元的贝叶斯推理	Langlois, T.	PDF	N/A	Bayesian inference by visuomotor neurons in prefrontal cortex
永久性噪音引起的听力损失后的听觉决策缺陷	Berns, M. P.	PDF	N/A	Auditory decision-making deficits after permanent noise-induced hearing loss
先天失明个体腹侧视觉流中对物体镜像的重复抑制，而非对盲文字母的重复抑制	Korczyk, M.	PDF	N/A	Repetition suppression for mirror images of objects and not Braille letters in the ventral visual stream of congenitally blind individuals
多效营养因子缺失可预防高脂饮食引起的认知功能障碍、神经胶质反应及海马区周围神经网的变化。	Caneque-Rufo, H.	PDF	N/A	Pleiotrophin deletion prevents high-fat diet-induced cognitive impairment, glial responses, and alterations of the perineuronal nets in the hippocampus
低强度脉冲超声波激活培养的海马神经元中的兴奋性突触网络	Li, F.	PDF	N/A	Low intensity pulsed ultrasound activates excitatory synaptic networks in cultured hippocampal neurons
体感皮层与身体表征：在视觉-本体感觉线索冲突期间更新运动系统	Mirdamadi, J. L.	PDF	N/A	Somatosensory cortex and body representation: Updating the motor system during a visuo-proprioceptive cue conflict
BDNF增强逆转了颅脑放射治疗引起的认知功能下降和神经退行性后果	El-Khatib, S. M.	PDF	N/A	BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences
神经网络结构如何改变大脑的自组织临界性	Sugimoto, Y. A.	PDF	N/A	How neural network structure alters the brain's self-organized criticality
不同类别的抗抑郁药物通常会改变小鼠苍白球的结构和功能	Abe, Y.	PDF	N/A	Distinct classes of antidepressants commonly act to shape pallidal structure and function in mice
被盗的未来：异常的海马神经发生导致癫痫中产生胶质细胞	Segasby, T.	PDF	N/A	A stolen future: aberrant hippocampal neurogenesis produces glial cells in epilepsy
缺失但未受糖皮质激素调节的促肾上腺皮质激素释放激素（Crh）调控小鼠的焦虑样行为	Friedman, H. R.	PDF	N/A	Absent, but not glucocorticoid-modulated, corticotropin-releasing hormone (Crh) regulates anxiety-like behaviors in mice
用于消融兴奋性和抑制性突触的工具箱	Bareghamyan, A.	PDF	N/A	A toolbox for ablating excitatory and inhibitory synapses
在活体细胞内成像显示，癫痫发作后皮质扩散性去极化期间，内质网钙离子出现耗竭。	Stern, M. A.	PDF	N/A	Organellular imaging in vivo reveals a depletion of endoplasmic reticular calcium during post-ictal cortical spreading depolarization
高速三维成像与25相机多焦点显微镜	Hirata-Miyasaki, E.	PDF	N/A	High-speed 3D Imaging with 25-Camera Multifocus Microscope
年龄对静息状态下皮层网络的影响	Gohil, C.	PDF	N/A	Effects of age on resting-state cortical networks
评估白尾鹿（Odocoileus virginianus）中蜱唾液和中肠细胞外囊泡作为抗蜱疫苗的效果	Gonzalez Gonzalez, J.	PDF	N/A	Evaluation of tick salivary and midgut extracellular vesicles as anti-tick vaccines in White-tailed deer (Odocoileus virginianus)
鼻内接种CPAF联合环二腺苷酸可诱导记忆性CD4 T细胞反应，并在经阴道感染鼠衣原体后减轻细菌负荷	Poston, T. B.	PDF	N/A	Intranasal immunization with CPAF combined with cyclic-di-AMP induces a memory CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum
感知到的压力会加重人体皮肤中的银屑病：来自人源化银屑病小鼠模型的见解	Zeltzer, A.	PDF	N/A	Perceived stress exacerbates psoriasis in human skin in vivo: Insights from a humanized psoriasis mouse model
啮齿动物PD1的进化指纹使其活性减弱，但增强了对肿瘤的免疫力，相较于人类PD1。	Masubuchi, T.	PDF	N/A	Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1
鉴定出一种关键的INO2等位基因，可增强工业发酵酵母菌株Saccharomyces cerevisiae的乙醇抗性	Albillos-Arenal, S.	PDF	N/A	Identification of a crucial INO2 allele for enhancing ethanol resistance in an industrial fermentation strain of Saccharomyces cerevisiae
志贺氏菌通过IpaH1.4介导的RNF213降解逃避LPS泛素化	Naydenova, K.	PDF	N/A	Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213
选择性保留北大西洋海洋中的岩藻糖丰富低聚糖	Bligh, M.	PDF	N/A	Selective preservation of fucose-rich oligosaccharides in the North Atlantic Ocean
时空、环境和行为因素对管理蜜蜂蜂群中瓦螨密度的预测作用	Boehm Vock, L.	PDF	N/A	Spatiotemporal, environmental, and behavioral predictors of Varroa mite intensity in managed honey bee apiaries
传粉者访问模式和差异性繁殖相容性维持了印度西高止山脉一种夜间开花的姜科植物的苞片颜色多态性	Shrotri, S.	PDF	N/A	Pollinator visitation pattern and differential reproductive compatibilities maintain bract colour polymorphism in a nocturnal ginger from Western Ghats, India
在孟加拉国亚热带季风气候下的半农村地区，果蝇（双翅目：实蝇科）的种群动态	Momen, M.	PDF	N/A	Population dynamics of fruit flies (Diptera: Tephritidae) in a semirural area under subtropical monsoon climate of Bangladesh
海洋碳输出可以通过基于海洋颜色的浮游植物群落来预测。	Kramer, S. J.	PDF	N/A	Ocean carbon export can be predicted from ocean color-based phytoplankton communities
蜂后餐桌上的农民？：蜜蜂（Apis mellifera）在准备蜂群过程中微生物群的动态变化	Kolasa, M. R.	PDF	N/A	Peasants at the queen's table?: The microbiome's dynamics throughout swarming preparation in honey bees (Apis mellifera)
季节性和年际稳定性在胶状绒紫菜（红藻门）种群遗传结构中的表现	Shainker-Connelly, S. J.	PDF	N/A	Seasonality and inter-annual stability in the population genetic structure of Batrachospermum gelatinosum (Rhodophyta)
细胞色素P450的自然变异独立于β-微管蛋白，改变了噻菌灵的反应。	Collins, J.	PDF	N/A	Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independent of beta-tubulin
利用单细胞eQTL分析鉴定导致代谢功能障碍相关脂肪性肝炎的个体水平变异基因	Hong, S. E.	PDF	N/A	Identification of genes conferring individual-level variation responsible for metabolic dysfunction-associated steatohepatitis using single-cell eQTL analysis
高阶上位性在大规模蛋白质序列-功能关系中的重要性	Sethi, P.	PDF	N/A	Importance of higher-order epistasis in large protein sequence-function relationships
单细胞多组学分析揭示了胚胎发育过程中转录与染色质相互作用的原则	Bhardwaj, V.	PDF	N/A	Single-cell multi-omic analysis reveals principles of transcription-chromatin interaction during embryogenesis
补充膳食纳米锌可通过调节铜锌超氧化物歧化酶表达来赋予更高的抗氧化状态	Tah, A.	PDF	N/A	Supplemental Dietary Nano Zinc Can Impart Higher Antioxidant Status by Modulating Cu-Zn SOD Expression
细胞收缩力驱动四维生物打印活体构建物的时空形态变化	Cleveland, D. S.	PDF	N/A	Cell Contractile Forces Drive Spatiotemporal Morphing in 4D Bioprinted Living Constructs
去细胞化细胞外基质（dECM）及其衍生墨水的成分的比较蛋白质组学分析与天然组织相比	Irastorza, A.	PDF	N/A	Comparative proteomic analysis of the composition of decellularized extracellular matrix (dECM) and dECM-based inks as compared to the native tissue
基于柔性石墨烯的神经技术用于帕金森病大鼠的高精度深脑映射和神经调控	Ria, N.	PDF	N/A	Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats
探索使用贝塔过程先验对贝叶斯生存分析中的基线危险进行灵活惩罚	Dauda, K. A.	PDF	N/A	Exploring the Flexible Penalization of Bayesian Survival Analysis Using Beta Process Prior for Baseline Hazard
实现单细胞声学定位与去激活超分辨率	Smith, C. A. B.	PDF	N/A	Achieving Single Cell Acoustic Localisation with Deactivation Super Resolution
PhysiofUS：一种基于组织运动的心率和呼吸率评估方法，用于神经功能超声成像	ZUCKER, N.	PDF	N/A	PhysiofUS : a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging
通过生物树脂分子量调节和多波长光学技术实现的多材料体积生物打印与即插即用悬浮浴生物制造	Ribezzi, D.	PDF	N/A	Multi-material volumetric bioprinting and plug-and-play suspension bath biofabrication via bioresin molecular weight tuning and multiwavelength optics
超越静态脑图谱：基于人工智能的开放数据库构建与全脑神经形态学动态挖掘	Jiang, S.	PDF	N/A	Beyond Static Brain Atlases: AI-Powered Open Databasing and Dynamic Mining of Brain-Wide Neuron Morphometry
AlphaMut：一种用于建议螺旋破坏性突变的深度强化学习模型	Bhargav, P.	PDF	N/A	AlphaMut: a deep reinforcement learning model to suggest helix-disrupting mutations
使用高光谱图像和机器学习对虾青素含量进行准确的无创定量	Calderini, M.	PDF	N/A	Accurate non-invasive quantification of astaxanthin content using hyperspectral images and machine learning
构建面向透明生物医学人工智能的文献知识库	Huang, Y.	PDF	N/A	Building a literature knowledge base towards transparent biomedical AI
AsaruSim：单细胞与空间RNA-Seq纳米孔长读长模拟工作流程	Hamraoui, A.	PDF	N/A	AsaruSim: a single-cell and spatial RNA-Seq Nanopore long-reads simulation workflow
磷酸化调控的无序核受体的构象多样性与拓扑动力学	Akulov, V.	PDF	N/A	Phosphorylation regulated conformational diversity and topological dynamics of an intrinsically disordered nuclear receptor
RNA G-四链体中肌苷、2'-O-甲基化和N6-甲基腺苷修饰的结构和动态后果：一项分子动力学研究	Dutta, N.	PDF	N/A	Structural and dynamic consequences of inosine, 2'-O-methylation, and N6-methyladenosine modifications in RNA G-quadruplex: A molecular dynamics study
甲基-CpG结合域蛋白维持表观遗传的机制模型	Dai, L.	PDF	N/A	Mechanistic model for epigenetic maintenance by methyl-CpG-binding domain proteins
线粒体泛素连接酶MARCHF5与MCL1合作抑制KSHV转化的原发性渗出性淋巴瘤细胞系的凋亡	Viswanathan, P.	PDF	N/A	The Mitochondrial Ubiquitin Ligase MARCHF5 Cooperates with MCL1 to Inhibit Apoptosis in KSHV-Transformed Primary Effusion Lymphoma Cell Lines
超级增强子分析揭示了ThPOK/ZBTB7B，一种CD4+细胞谱系承诺因子，作为主调控因子，限制乳腺癌细胞呈现管腔非迁移表型。	Arcuschin, C. D.	PDF	N/A	Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype
MAX失活会扰乱MYC网络，并在多种组织中诱导神经内分泌肿瘤的形成。	Freie, B.	PDF	N/A	MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues
肺腺癌对顺铂和培美曲塞化疗耐药现象中Orai3通道和ABC型转运蛋白的特征及意义。	Daoudi, R.	PDF	N/A	Characterization and implication of the Orai3 channel and ABC type transporters in the phenomenon of chemoresistance to cisplatin and pemetrexed in lung cancer.
头颈部癌症中纳米气泡超声造影剂的异质动力学与血管生成信号传导	Van Court, B.	PDF	N/A	Heterogeneous Kinetics of Nanobubble Ultrasound Contrast Agent and Angiogenic Signaling in Head and Neck Cancer
血小板中密集但不包含α颗粒的成分对于胰腺β细胞分泌胰岛素是必需的。	Kolczynska-Matysiak, K.	PDF	N/A	Dense but not alpha granules of platelets are required for insulin secretion from pancreatic beta cells
评估SUBI和DRO1渗入系在不同生长阶段下对淹水和干旱条件的耐受性	Soe, I.	PDF	N/A	Assessing Stress Tolerance of SUBI and DRO1 Introgression lines Under Flooding and Drought Conditions at Different Growth Stages
过氧化物酶2介导了人类骨骼肌肌管中由收缩活动诱导的氧化磷酸化过程中对氧化还原刺激的适应性变化。	Heaton, R. A.	PDF	N/A	Peroxiredoxin 2 mediates redox-stimulated adaptations to oxidative phosphorylation induced by contractile activity in human skeletal muscle myotubes
多器官转录组图谱揭示了分娩的特征	Ni, D.	PDF	N/A	Multi-organ transcriptomic atlas reveals hallmarks of labor
四吡咯生物合成酶的自然变异及其调控机制改变了叶绿素突变体Oy1-N1989的特性。	Kaur, A.	PDF	N/A	Natural variation in tetrapyrrole biosynthetic enzymes and their regulation modify the chlorophyll mutant Oy1-N1989
对七种开花植物中选择性剪接、长链非编码RNA和环状RNA的综合注释	Gabel, A.	PDF	N/A	Comprehensive annotations of alternative splicing, lncRNAs, and circRNAs in seven species of flowering plants
从基因到通路：一种精选基因方法在硬骨鱼转录组学中准确重建通路的应用	Herrera, M.	PDF	N/A	From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics
DrugTar通过整合大型语言模型和基因本体论，提升了药物预测能力。	Borhani, N.	PDF	N/A	DrugTar Improves Druggability Prediction by Integrating Large Language Models and Gene Ontologies
鸡蛋辐照对野生型和沃尔巴克氏体转染的埃及伊蚊蚊媒发育和致育性的影响	Kittayapong, P.	PDF	N/A	Effect of egg irradiation on development and sterility of wild-type and Wolbachia trans-infected Aedes aegypti mosquito vectors
运动准备在时间决策中追踪决策边界交叉	Ofir, N.	PDF	N/A	Motor preparation tracks decision boundary crossing in temporal decision-making
淀粉样β蛋白诱导的培养星形胶质细胞中快速局部钙升高的改变	Nakata, K.	PDF	N/A	Amyloid-β-induced Alteration of Fast and Localized Calcium Elevations in Cultured Astrocytes
为什么我们有这么多兴奋性神经元？	Wang, Q.	PDF	N/A	Why do we have so many excitatory neurons?
CX3CR1 调节常驻小胶质细胞向脑损伤部位的迁移	Wagner, J.	PDF	N/A	CX3CR1 modulates migration of resident microglia towards brain injury
内源性大麻素2-花生四烯酰甘油通过细胞外微泡按需释放和运输	Straub, V. M.	PDF	N/A	The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles
阿尔茨海默病小鼠模型中CA1和CA3区位细胞功能的明显紊乱	Park, S.	PDF	N/A	Distinct Disruptions in CA1 and CA3 Place Cell Function in Alzheimer's Disease Mice
在自由活动的小鼠进行探索行为期间，胡须体感皮层的具身处理	Gantar, L.	PDF	N/A	Embodied processing in whisker somatosensory cortex during exploratory behaviour in freely moving mice
触须剥夺引发了一种特殊的皮层稳态可塑性，但在Fmr1 KO中这种可塑性受损。	Lakhani, A.	PDF	N/A	Whisker deprivation triggers a distinct form of cortical homeostatic plasticity that is impaired in the Fmr1 KO
白细胞介素37抗炎复合物的计算建模	Sardag, I.	PDF	N/A	Computational Modeling of the Anti-Inflammatory Complexes of IL37
A2.CAR Treg与抗CD154联合治疗在小鼠同种异体不匹配心脏移植模型中的疗效及局限性	Durgam, S. S.	PDF	N/A	Efficacy and limitations of combined A2.CAR Treg and anti-CD154 therapy in a mouse model of haplo-mismatched heart transplantation
母体免疫保护后代免受肠道病毒感染，同时不会对体液免疫记忆产生负面影响。	Muleta, K. G.	PDF	N/A	Maternal immunity protects offspring from enteric viral infection without negatively affecting humoral immune memory
利用内质网滞留信号工程化CD3亚基促进异基因CAR T细胞生产	Ebrahimiyan, H.	PDF	N/A	Engineering CD3 Subunits with Endoplasmic Reticulum Retention Signal Facilitates Allogeneic CAR T Cell Production
BiMultiNetPlot：一个用于可视化生态二分多层网络的R包	Li, H.-D.	PDF	N/A	BiMultiNetPlot: An R package for visualizing ecological bipartite multilayer networks
小型哺乳动物及其洞穴塑造了球孢子菌在土壤中的分布：一项长期的生态实验	Head, J. R.	PDF	N/A	Small mammals and their burrows shape the distribution of Coccidioides in soils: a long-term ecological experiment
趋异选择和可塑性在物种形成初期塑造了生殖隔离	Jarrett, B. J. M.	PDF	N/A	Divergent selection and plasticity shape reproductive isolation at the onset of speciation
饮食特化推动了雁形目（Anseriformes）在头骨和附肢骨骼上的适应、趋同和整合。	Chatterji, R. M.	PDF	N/A	Dietary specialization drives adaptation, convergence, and integration across the cranial and appendicular skeleton in Waterfowl (Anseriformes).
古代生物分子表明已灭绝的洞熊具有学习觅食策略	Meleg, I. N.	PDF	N/A	Ancient biomolecules suggest learned foraging strategy in extinct cave bears
在野生酵母模型中非整倍体回复的速率	Gasch, A. P.	PDF	N/A	On the rate of aneuploidy reversion in a wild yeast model
全球土壤传播蠕虫的多样性揭示了影响诊断目标的群体偏向性遗传变异	Papaiakovou, M.	PDF	N/A	Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets
Rfam 15：2025年的RNA家族数据库	Ontiveros-Palacios, N.	PDF	N/A	Rfam 15: RNA families database in 2025
大规模突变扫描和深度学习的转录抑制域预测与设计	Valbuena, R.	PDF	N/A	Prediction and design of transcriptional repressor domains with large-scale mutational scans and deep learning
巴巴利猕猴社交信息的化学特征	Weiss, B. M.	PDF	N/A	Chemical signatures of social information in Barbary macaques
可操控的弹簧带针用于在组织中自主急转弯	Abdoun, O.	PDF	N/A	Steerable Tape-Spring Needle for Autonomous Sharp Turns Through Tissue
STANCE：一种统一的统计模型，用于在空间转录组学中检测细胞类型特异的空间变异基因	Su, H.	PDF	N/A	STANCE: a unified statistical model to detect cell-type-specific spatially variable genes in spatial transcriptomics
基于OPLS的多类分类与数据驱动的类间关系发现	Forsgren, E.	PDF	N/A	OPLS-based Multiclass Classification and Data-Driven Inter-Class Relationship Discovery
药物化学中的AI增强R基团探索	Zhao, H.	PDF	N/A	AI-Augmented R-Group Exploration in Medicinal Chemistry
隐神经刺激对两种不同膀胱状态（活动不足和活动过度）的兴奋和抑制作用	li, C.	PDF	N/A	Excitatory and Inhibitory Effects of Saphenous Nerve Stimulation on Two Different Bladder Conditons: Underactivity and Overactivity
睡眠期间心率变异性受损：REM睡眠行为障碍、创伤性脑损伤及创伤后应激障碍退伍军人中自主神经功能障碍的早期潜在窗口？	Cunningham, H. A.	PDF	N/A	Heart rate variability impairment during sleep in Veterans with REM sleep behavior disorder, traumatic brain injury, and posttraumatic stress disorder: An early potential window into autonomic dysfunction?
健康数据科学教育洞察：定性内容分析	Rohani, N.	PDF	N/A	Insights into Health Data Science Education: A Qualitative Content Analysis
人类溶质载体超家族的代谢图谱	Wiedmer, T.	PDF	N/A	Metabolic mapping of the human solute carrier superfamily
需要腿部顺应性来解释不同步态中的地面反作用力模式和速度范围。	Safa, A. T.	PDF	N/A	Leg compliance is required to explain the ground reaction force patterns and speed ranges in different gaits
人类听觉皮层中的时间整合主要与绝对时间相关，而非结构持续时间。	Norman-Haignere, S. V.	PDF	N/A	Temporal integration in human auditory cortex is predominantly yoked to absolute time, not structure duration
Na+/K+-ATPase的生电性给高度活跃的尖峰细胞的计算带来了挑战。	Weerdmeester, L.	PDF	N/A	The electrogenicity of the Na+/K+-ATPase poses challenges for computation in highly active spiking cells
心脏对听觉不规则性的反应揭示了睡眠期间的分层信息处理	Koroma, M.	PDF	N/A	Cardiac responses to auditory irregularities reveal hierarchical information processing during sleep
microRNA-138-5p在小脑输入层抑制兴奋性突触强度	Delvendahl, I.	PDF	N/A	microRNA-138-5p suppresses excitatory synaptic strength at the cerebellar input layer
TMX1是一种二硫键氧化还原酶，通过调节CD3zeta对T细胞功能至关重要。	Chai, T.	PDF	N/A	TMX1, a disulfide oxidoreductase, is necessary for T cell function through regulation of CD3zeta
CXCL16-CXCR6的进化多样性：爬行动物中的趋同替代和反复基因丢失	Salve, B. G.	PDF	N/A	Evolutionary diversity of CXCL16-CXCR6: Convergent Substitutions and Recurrent Gene Loss in Sauropsids
EGO-1和RRF-1在调控秀丽隐杆线虫生殖系外源RNAi效率中的双重作用	Dejima, K.	PDF	N/A	Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans
一个支持法国淡水环境中水生大型无脊椎动物DNA条形码分析的注释参考库	Gauvin, P.	PDF	N/A	An annotated reference library for supporting DNA metabarcoding analysis of aquatic macroinvertebrates in French freshwater environments
对111个鲽形目线粒体基因组的全面分析：结构、保守性、变异及进化的见解	Tan, S.	PDF	N/A	Comprehensive analysis of 111 Pleuronectiformes mitochondrial genomes: insights into structure, conservation, variation and evolution
利用长读长测序和基因组组装鉴定出Aspergillus wentii的萜类合成酶武器库	Olumakaiye, R.	PDF	N/A	Identification of a terpene synthase arsenal using long-read sequencing and genome assembly of Aspergillus wentii
人类长非编码RNA的基因组生物学：虚拟核型	Palma, A.	PDF	N/A	Genome biology of long non-coding RNAs in humans: a virtual karyotype
Jaeger：一种准确且快速的深度学习工具，用于检测噬菌体序列	Wijesekara, Y.	PDF	N/A	Jaeger: an accurate and fast deep-learning tool to detect bacteriophage sequences
通过厚组织的空间转录组学在空间和时间上解卷积器官发生	Asami, S.	PDF	N/A	Deconvolving organogenesis in space and time via spatial transcriptomics in thick tissues
哺乳动物启动子具有RNA聚合酶II低占用率和高周转率的特点。	Chatsirisupachai, K.	PDF	N/A	Mammalian promoters are characterised by low occupancy and high turnover of RNA polymerase II
双歧杆菌假链状菌的胶囊性胞外多糖增强了临床前乳腺癌中的全身抗肿瘤免疫	Price, C. A.	PDF	N/A	Bifidobacterium pseudocatenulatum capsular exopolysaccharide enhances systemic anti-tumour immunity in pre-clinical breast cancer
同时分析克罗恩病和有症状对照组的血液和肠道T细胞和B细胞库，揭示了克罗恩病患者免疫库的组织特异性改变	Mahdy, A. K. H.	PDF	N/A	Simultaneous Profiling of the Blood and Gut T and B Cell Repertoires in Crohn's Disease and Symptomatic Controls Illustrates Tissue-specific Alterations in the Immune Repertoire of Crohn's Disease Patients
偷听食草动物：使用接触式麦克风量化植物-昆虫相互作用	Mehrotra, D.	PDF	N/A	Eavesdropping on Herbivores: Using contact microphones to quantify Plant-Insect Interactions
绘制与小麦病原菌Zymoseptoria tritici温度胁迫相关的基因组区域图谱	Stapley, J.	PDF	N/A	Mapping genomic regions associated with temperature stress in the wheat pathogen Zymoseptoria tritici
BRCA1、BRCA2和PALB2变异分类中共同分离分析的综合且易获取模型	Moghadasi, S.	PDF	N/A	A Comprehensive and Accessible Model for Co-Segregation Analysis in BRCA1, BRCA2, and PALB2 Variant Classification
dScaff - 一个基于参考基因组数据，用于自动搭建从头组装草图的生物信息学框架	Constantin, N. D.	PDF	N/A	dScaff - an automatic bioinformatics framework for scaffolding draft de novo assemblies based on reference genome data
艺术X的相机路径、建模及图像处理工具	Ermel, U. H.	PDF	N/A	Camera Paths, Modeling, and Image Processing Tools for ArtiaX
肝细胞中线粒体复合体III功能的恢复突显了肝脏作为独立于棕色脂肪细胞激活的关键产热器官的作用。	Banerjee, R.	PDF	N/A	Restoration of mitochondrial complex III function in hepatocytes highlights the liver as a key thermogenic organ independent of brown adipocyte activation
探索记忆性景观：双曲几何揭示物体概念记忆中的层次结构	Lee, F. M.	PDF	N/A	Navigating Memorability Landscapes: Hyperbolic Geometry Reveals Hierarchical Structures in Object Concept Memory
来自ADHD诱导的多能干细胞（iPSC）模型的多巴胺能神经元的转录组分析	Namipashaki, A.	PDF	N/A	Transcriptome profiling of dopaminergic neurons derived from an ADHD induced pluripotent stem cell (iPSC) model
评估秘鲁塔克纳地区土壤中潜在有毒元素及其由环境责任引发的潜在生态风险	Caceda Quiroz, C. J.	PDF	N/A	Evaluation of Potentially Toxic Elements in Soil and Potential Ecological Risks Generated by Environmental Liabilities in Tacna, Peru
对用于人口控制的自我限制遗传控制策略的比较评估	Han, Y.	PDF	N/A	A comparative assessment of self-limiting genetic control strategies for population suppression
通过基于针的腔扩张方法捕获的生物材料演化特性	Varner, H. M.	PDF	N/A	Evolving properties of biological materials captured via needle-based cavity expansion method
模仿机制：肉类与肉类替代品的比较	St. Pierre, S. R.	PDF	N/A	Mimicking mechanics: A comparison of meat and meat analogs
高通量实证与虚拟筛选发现乳腺癌中多倍体巨型癌细胞的新型抑制剂	Ma, Y.	PDF	N/A	High-Throughput Empirical and Virtual Screening to Discover Novel Inhibitors of Polyploid Giant Cancer Cells in Breast Cancer
具有独立调控粘附配体迁移率和粘弹性的水凝胶可增强细胞粘附和扩展	Moghaddam, A. S.	PDF	N/A	Hydrogels with Independently Controlled Adhesion Ligand Mobility and Viscoelasticity Increase Cell Adhesion and Spreading
通过氧化苯酚偶联在细胞上共价结合生物材料，通过细胞内生物物理编程调节干细胞命运	Johnbosco, C.	PDF	N/A	Covalent on-cell conjugation of biomaterials through oxidative phenolic coupling regulates stem cell fate via intracellular biophysical programming
scParadise：可调节的高精度多任务细胞类型注释与表面蛋白丰度预测	Chechekhina, E.	PDF	N/A	scParadise: Tunable highly accurate multi-task cell type annotation and surface protein abundance prediction
残留物替代对蛋白质细胞丰度的影响	Schulze, T. K.	PDF	N/A	Effects of residue substitutions on the cellular abundance of proteins
核小体定位和聚合物力学解释了100千碱基尺度的基因组接触	Corrette, J.	PDF	N/A	Nucleosome placement and polymer mechanics explain genomic contacts on 100kbp scales
丙戊酸对髓母细胞瘤中干细胞和分化调节因子的调控	Freire, N. H.	PDF	N/A	Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma
破表者：基于微孔阵列的微型胸腺类器官模型的建立，适用于高通量应用。	Major, V.	PDF	N/A	Watch-breaker: establishment of a microwell array-based miniaturized thymic organoid model suitable for high throughput applications.
通过在三维培养中使用倾向神经转录因子刺激人类视网膜的再生能力	Wohlschlegel, J.	PDF	N/A	Stimulating the regenerative capacity of the human retina with proneural transcription factors in 3D cultures
空间结构对崎岖适应性景观中早期和长期适应的影响	Servajean, R.	PDF	N/A	Impact of spatial structure on early and long-term adaptation in rugged fitness landscapes
斑胸草雀距离呼叫声学特征的依赖于情境的调制：来自一种新颖的目标导向发声范式的见解	Safarcharati, Z.	PDF	N/A	Context-Dependent Modulations in Acoustic Features of Zebra Finch Distance Calls: Insights from a Novel Goal-Directed Vocalization Paradigm
斑马鱼视锥视蛋白光谱位移的分子机制	Chi, L. A.	PDF	N/A	Molecular Mechanisms Underlying the Spectral Shift in Zebrafish Cone Opsins
在多稳态知觉过程中，观察者会经历哪些感知类别？	Skerswetat, J.	PDF	N/A	Which perceptual categories do observers experience during multistable perception?
通过DynamicNeuronTracker揭示了单个化学感觉神经元对外部刺激的小鼠组织切片组合反应性	Noh, J.	PDF	N/A	Combinatorial responsiveness of single chemosensory neurons to external stimulation of mouse explants revealed by DynamicNeuronTracker
Akap11 突变小鼠（一种精神分裂症和双相情感障碍的遗传模型）中，突触PKA活性升高以及纹状体多巴胺信号传导异常。	Song, B. J.	PDF	N/A	Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder
人背根神经节中端细胞的转录组学和组织学特征	Haberberger, R. V.	PDF	N/A	Transcriptomic and histological characterization of telocytes in the human dorsal root ganglion
睡眠剥夺小鼠大脑皮层细胞特异性转录组和核蛋白组的整合分析	Jha, P. K.	PDF	N/A	An integrative analysis of cell-specific transcriptomics and nuclear proteomics of sleep-deprived mouse cerebral cortex
从诱导多能干细胞发展而来的内皮向造血转变的发育调控	Wellington, R.	PDF	N/A	Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells
动态转录和表观遗传变化定义了出生后肌腱的生长	Dingwall, H. L.	PDF	N/A	Dynamic transcriptional and epigenetic changes define postnatal tendon growth
动态BMP信号调节斑马鱼中生骨节的诱导和谱系多样化	Xie, L.	PDF	N/A	Dynamic BMP signaling regulates sclerotome induction and lineage diversification in zebrafish
一种优化用于生长和发育的果蝇全营养饮食	Sorge, S.	PDF	N/A	A Drosophila holidic diet optimised for growthand development
Api-TRACE：一种用于在受限环境中追踪蜜蜂的系统，旨在研究蜜蜂学习过程及锂对学习的影响	Erdem, B.	PDF	N/A	Api-TRACE: A System for Honey Bee Tracking in a Constrained Environment to Study Bee Learning Process and the Effect of Lithium on Learning
语音解码能力与左侧弓状束的纤维密度在阅读发展的纵向过程中存在关联。	Perdue, M. V.	PDF	N/A	Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development
脂肪细胞代谢状态调节胶质细胞吞噬功能	Rajan, A.	PDF	N/A	Adipocyte metabolic state regulates glial phagocytic function
在一种可调控TDP-43的小鼠模型中，超兴奋性先于CA3海马神经退行性变，该模型模拟了ALS-FTD（肌萎缩侧索硬化-额颞叶痴呆）。	Rodemer, W.	PDF	N/A	Hyperexcitability precedes CA3 hippocampal neurodegeneration in a dox-regulatable TDP-43 mouse model of ALS-FTD.
BrainScale：在脉冲神经网络中实现可扩展的在线学习	Wang, C.	PDF	N/A	BrainScale: Enabling Scalable Online Learning in Spiking Neural Networks
Pdgfab/Pdgfra介导的趋化作用引导了来自肌节衍生的成纤维细胞前体在斑马鱼中的迁移	Mendez-Olivos, E. E.	PDF	N/A	Pdgfab/Pdgfra-mediated chemoattraction guides the migration of sclerotome-derived fibroblast precursors in zebrafish
# BioRxiv 2024-09-23 Papers

标题	作者	PDF链接	代码仓库	Title
多感官序列预测背后的振荡多时间尺度机制	Wang, P.	PDF	N/A	Oscillatory multi-timescale mechanisms underlying multisensory sequence prediction
使用“AngioTag”斑马鱼在体内分析内皮翻译组	Miller, M. F.	PDF	N/A	Profiling the endothelial translatome in vivo using 'AngioTag' zebrafish
基于探索的学习稳定控制器预测运动适应	Seethapathi, N.	PDF	N/A	Exploration-based learning of a stabilizing controller predicts locomotor adaptation
损伤后存活的DA SN神经元中Kv4.3介导的节律性可塑性与全内源性放电范围的恢复相关	Kovacheva, L.	PDF	N/A	Recovery of the full in vivo firing range in post-lesion surviving DA SN neurons associated with Kv4.3-mediated pacemaker plasticity
超越梯度：干扰和泛化的分解、几何控制	Scott, D. N.	PDF	N/A	Beyond gradients: Factorized, geometric control of interference and generalization
微卫星密度图谱展示了完整参考人类基因组中的短串联重复聚集情况	Xia, Y.	PDF	N/A	Microsatellite Density Landscapes Illustrate Short Tandem Repeats Aggregation in The Complete Reference Human Genome
通过多步行者监督分子动力学（mwSuMD）解决的隐藏GPCR结构转变	Deganutti, G.	PDF	N/A	Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
快速解聚和纤毛蛋白的力学敏感性支持在网格蛋白介导的内吞作用中快速周转	Mousavi, S. I.	PDF	N/A	Fast actin disassembly and fimbrin mechanosensitivity support rapid turnover during clathrin-mediated endocytosis
等压交联质谱技术用于研究蛋白质及其复合物的构象和结构变化	Ranish, J.	PDF	N/A	Isobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and complexes
铁死亡整合线粒体功能障碍和病理性炎症以促进肺动脉高压	Kazmirczak, F.	PDF	N/A	Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension
改进的排列检验方法能够在非平稳时间序列的重复次数有限的情况下，检测出它们之间的依赖关系。	Yuan, A. E.	PDF	N/A	Improved permutation tests enable detection of dependence between nonstationary time series despite limited numbers of replicates
改进的排列检验方法能够在非平稳时间序列之间检测到依赖关系，即使重复次数有限。	Yuan, A. E.	PDF	N/A	Improved permutation tests enable detection of dependence between nonstationary time series despite limited numbers of replicates
NEURD 提供连接组学的自动校对和特征提取功能。	Celii, B.	PDF	N/A	NEURD offers automated proofreading and feature extraction for connectomics
mosna揭示了不同类型的细胞相互作用，这些相互作用可预测对免疫疗法的反应和癌症中的生存情况。	Coullomb, A.	PDF	N/A	mosna reveals different types of cellular interactions predictive of response to immunotherapies and survival in cancer
PAPET：从PacBio SequelII数据中识别5-甲基胞嘧啶的高效算法集合	Groux, R.	PDF	N/A	PAPET: a collection of performant algorithms to identify 5-methyl cytosine from PacBio SequelII data
皮质回路中实时学习的神经最小作用原理	Senn, W.	PDF	N/A	A neuronal least-action principle for real-time learning in cortical circuits
将生物相互作用纳入生态位分析中，揭示了小丑鱼群落组成的模式	Garcia, A.	PDF	N/A	Integrating Biotic Interactions In Niche Analyses Unravels Patterns Of Community Composition in Clownfishes
逆转弱碱性药物的质子化作用极大地增强了其细胞内扩散，并减少了溶酶体的隔离。	DEY, D.	PDF	N/A	Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration
METASPACE-ML：利用机器学习进行成像质谱的特定背景代谢物注释	Wadie, B.	PDF	N/A	METASPACE-ML: Context-specific metabolite annotation for imaging mass spectrometry using machine learning
睡眠依赖性记忆过程中RNA加工基因的调控	Li, Y.	PDF	N/A	Modulation of RNA processing genes during sleep-dependent memory
肌纤维特异性敲除TGF-β I型受体可引发肌肉肥大，并促进肌肉收缩和氧化代谢。	Shi, A.	PDF	N/A	Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism
人的知识在独立的大脑系统中分别通过外向参照系和内向参照系进行独立编码。	Chavez, R. S.	PDF	N/A	Person knowledge is independently encoded by allocentric and egocentric reference frames within separate brain systems
物体、面孔和空间：个体行为差异所体现的视觉物体知觉的组织原则	Sigurdardottir, H. M.	PDF	N/A	Objects, faces, and spaces: Organizational principles of visual object perception as evidenced by individual differences in behavior
CENP-E通过对抗Aurora激酶来促进端对端附着，从而启动染色体排列。	Vukusic, K.	PDF	N/A	CENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on attachments
BioMANIA：通过对话简化生物信息学数据分析	Dong, Z.	PDF	N/A	BioMANIA: Simplifying bioinformatics data analysis through conversation
锌指同源盒-3（ZFHX3）调控视交叉上核中全基因组的每日基因表达	Bafna, A.	PDF	N/A	Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus
Epiregulon：推断单细胞转录因子活性以预测药物反应和细胞状态的驱动因素	Wlodarczyk, T.	PDF	N/A	Epiregulon: Inference of single-cell transcription factor activity to predict drug response and drivers of cell state
药物输送的动力学决定了细菌对抗生素反应的进化过程	Crow, J. C.	PDF	N/A	Dynamics of drug delivery determines course of evolution of antibiotic responses in bacteria
在14特斯拉场强下进行高分辨率清醒小鼠功能性磁共振成像	Hike, D.	PDF	N/A	High-resolution awake mouse fMRI at 14 Tesla
eMOSAIC：多模态分布外不确定性量化简化了大规模多药理学研究	Badkul, A.	PDF	N/A	eMOSAIC: Multi-modal Out-of-distribution Uncertainty Quantification Streamlines Large-scale Polypharmacology
昼夜节律神经肽PDF对活动节律具有性别二态性效应	Iyer, A. R.	PDF	N/A	The Circadian Neuropeptide PDF has Sexually Dimorphic Effects on Activity Rhythms
模拟安大略湖近岸与离岸水交换	Hlevca, B.	PDF	N/A	Modeling nearshore-offshore water exchange in Lake Ontario
灵长类大脑尺寸/身体尺寸关系中进化滞后的重要性	Dunbar, R. I. M.	PDF	N/A	Significance of Evolutionary Lags in the Primate Brain Size/Body Size Relationship
一种通用且有效的去条纹变分方法：应用于光片显微镜、聚焦离子束扫描电镜和遥感图像	Rottmayer, N.	PDF	N/A	A universal and effective variational method for destriping: application to light-sheet microscopy, FIB-SEM and remote sensing images
Hill-Robertson干扰可能会影响对高度自交物种中新突变适应性效应的推断	Daigle, A.	PDF	N/A	Hill-Robertson interference may bias the inference of fitness effects of new mutations in highly selfing species
在视觉受损的大脑中，从感官到知觉的盲文字母表征的转变	Haupt, M.	PDF	N/A	The transformation of sensory to perceptual braille letter representations in the visually deprived brain
保护计划下小种群基因组多样性的趋势：以两种法国鸡品种为例的研究	Bortoluzzi, C.	PDF	N/A	Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds
高效生成蛋白质口袋的工具——PocketGen	Zhang, Z.	PDF	N/A	Efficient Generation of Protein Pockets with PocketGen
在情景记忆的形成和回忆过程中，显著网络、默认模式网络和前顶叶网络的电生理动力学：一项多实验的iEEG重复研究	Das, A.	PDF	N/A	Electrophysiological dynamics of salience, default mode, and frontoparietal networks during episodic memory formation and recall: A multi-experiment iEEG replication
基因背景和发育状态对胶质母细胞瘤患者来源细胞信号通路及治疗反应的影响	Berezovsky, A. D.	PDF	N/A	Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells
使用TREAT和otter分析长读长测序平台上的串联重复复杂性	Tesi, N.	PDF	N/A	Characterising tandem repeat complexities across long-read sequencing platforms with TREAT and otter
转录组学和跨细胞器互补揭示了12-cis-oxo-植物二烯酸在受伤的拟南芥中有限的信号传导能力	Mekkaoui, K.	PDF	N/A	Transcriptomics and trans-organellar complementation reveal a limited signaling capacity of 12-cis-oxo-phytodienoic acid in wounded Arabidopsis
从背外侧前额叶皮质的转录组和表观组数据推断女性阿尔茨海默病患者的多种疾病进展路径的可能性	Honda, K.	PDF	N/A	Possibilities of multiple disease progression pathways in female Alzheimer's disease patients inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex
专家导航员采用基于合理复杂性的决策优先级排序，用于大规模现实世界规划	Fernandez Velasco, P.	PDF	N/A	Expert Navigators Deploy Rational Complexity-Based Decision Prioritization for Large-Scale Real-World Planning
寄生在非洲慈鲷鱼上的桡足类寄生虫Ergasilus kandti的线粒体基因组、系统发育位置及分布更新	Jansen, D.	PDF	N/A	Mitogenomics, phylogenetic position, and updated distribution of Ergasilus kandti, an ergasilid copepod parasitizing African cichlid fishes
活细胞荧光显微镜 - 高通量图像与数据分析的端到端工作流程	Zahumensky, J.	PDF	N/A	Live Cell Fluorescence Microscopy - An End-to-End Workflow for High-Throughput Image and Data Analysis
MRAP2 修饰黑皮质素-4受体的信号传导和寡聚化状态。	Sohail, I.	PDF	N/A	MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor
G蛋白偶联受体激酶2（GRK2）调控毛囊稳态	Asensio, A.	PDF	N/A	The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
定义表观遗传抑制对肺癌细胞反应的异质分子图谱	Lin, C.	PDF	N/A	Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition
预测肺移植后原发性移植物功能障碍：基于机器学习的生物标志物发现	Nord, D.	PDF	N/A	Predicting Primary Graft Dysfunction in Lung Transplantation: Machine Learning-Guided Biomarker Discovery
在已发现的癌症驱动核苷酸（CDNs）中——基因、癌症类型和患者之间的分布情况	Zhang, L.	PDF	N/A	On the discovered Cancer Driving Nucleotides (CDNs)-Distributions across genes, cancer types and patients
大规模重复进化与癌症驱动核苷酸（CDNs）完全鉴定的理论	Zhang, L.	PDF	N/A	The theory of massively repeated evolution and full identifications of Cancer Driving Nucleotides (CDNs)
PhyloFunc：作为元蛋白质组数据分析中一种新型生态学指标的系统发育功能距离	Wang, L.	PDF	N/A	PhyloFunc: Phylogeny-informed Functional Distance as a New Ecological Metric for Metaproteomic Data Analysis
原噬菌体与铜绿假单胞菌临床分离株的抗生素耐药性关联不频繁	Chang, T. H.	PDF	N/A	Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates
大麻二酚与益生菌的协同作用可以抑制血糖指标，增强胰岛素分泌，并缓解2型糖尿病的症状。	Naeini, S. E.	PDF	N/A	The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes.
多囊卵巢综合征小鼠模型中的GnRH脉冲发生器活性	Zhou, Z.	PDF	N/A	GnRH pulse generator activity in mouse models of polycystic ovary syndrome
一种类人轮廓整合的前馈机制	Doshi, F. R.	PDF	N/A	A feedforward mechanism for human-like contour integration
多发性硬化进展中的性别差异单细胞图谱	Soler-Saez, I.	PDF	N/A	Single cell landscape of sex differences in the progression of multiple sclerosis
选择针对不同手性RNA元件的氟化适配体	Dantsu, Y.	PDF	N/A	Selection of Fluorinated Aptamer Targeting RNA Element with Different Chirality
巨蜂鸟（Patagona spp.）（鸟类：蜂鸟科）的分类学、命名法及鉴定	Williamson, J. L.	PDF	N/A	Taxonomy, nomenclature, and identification of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae)
构建镜像RNA纳米结构以增强生物稳定性和药物递送效率	Zhang, Y.	PDF	N/A	Construction of mirror-image RNA nanostructure for enhanced biostability and drug delivery efficiency
基因功能在随机基因沉默的瞬间被揭示	Gupta, S.	PDF	N/A	Gene Function Revealed at the Moment of Stochastic Gene Silencing
桡足类化学信号对两种拟菱形藻细胞内和细胞外毒素的影响	Pourdanandeh, M.	PDF	N/A	Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis
最近的研究表明，气味体验能够有选择性地调节小鼠嗅球中嗅觉敏感度，这种调节作用跨越了嗅球中的小球输出层。	Subramanian, N.	PDF	N/A	Recent odor experience selectively modulates olfactory sensitivity across the glomerular output in the mouse olfactory bulb
线粒体叶酸代谢紊乱会导致线粒体DNA泄漏，并激活细胞凋亡或炎症通路。	Hwang, S.	PDF	N/A	Disruption of mitochondrial folate metabolism leads to mitochondrial DNA leakage and activation of apoptotic or inflammatory pathways
质粒病毒维持使细菌种群从感染中恢复并实现病毒-细菌共存	Sanchez-Martinez, R.	PDF	N/A	Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence
大肠杆菌细胞中DnaA和DNA的相对分布及其表型变异性的因素	Namboodiri, S. K.	PDF	N/A	Relative Distribution of DnaA and DNA in Escherichia coli Cells as a Factor of Their Phenotypic Variability
在肢体发育过程中，En1的时间表达错误会导致不同的表型。	Ringel, A. R.	PDF	N/A	Temporal misexpression of En1 during limb development causes distinct phenotypes
一类新的受体：脂质通过其膜锚定物调节哺乳动物Gsα刺激的腺苷酸环化酶活性	Landau, M.	PDF	N/A	A new class of receptors: Lipids regulate mammalian Gsalpha-stimulated adenylyl cyclase activities via their membrane anchors
通过一种具有可解释注意力单元的新型深度学习模型探索核定位信号宇宙	Li, Y.	PDF	N/A	Discovering nuclear localization signal universe through a novel deep learning model with interpretable attention units
网格蛋白介导的内吞作用中的囊泡化途径	Wang, X.	PDF	N/A	Vesiculation pathways in clathrin-mediated endocytosis
乳腺癌上皮-间充质转化及器官特异性转移中三维基因组结构的重新排列	Das, P.	PDF	N/A	Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism
人类从腹侧壳核到运动皮层区域的假定开环电路的解离研究 I：高分辨率连接组学	Rizor, E. J.	PDF	N/A	Dissociation of putative open loop circuit from ventral putamen to motor cortical areas in humans I: high-resolution connectomics
评估生理指标在通过比较问题测试（CQT）检测欺骗和真实性中的应用	Rashid, A. M. S.	PDF	N/A	Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT)
DNMT1介导的抑制性中间神经元迁移调控影响皮层结构和功能	Reichard, J.	PDF	N/A	DNMT1-Mediated Regulation of Inhibitory Interneuron Migration Impacts Cortical Architecture and Function
转录调控因子HcpR的全长结构及其与血红素的结合	Belvin, B. R.	PDF	N/A	Full-length structure and heme binding in the transcriptional regulator HcpR
肌动蛋白丝切割和封端的机制：凝溶胶蛋白的作用	Barrie, K. R.	PDF	N/A	Mechanism of Actin Filament Severing and Capping by Gelsolin
神经内分泌通过果蝇血管壁龛调控肠道再生	Medina, A.	PDF	N/A	Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila.
神经营养因子artemin及其受体GFRα3通过离子通道TRPM8介导偏头痛样疼痛。	Yang, C.	PDF	N/A	The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8
通过考虑树突计算来克服运动传感器模型的局限性	Luna, R.	PDF	N/A	Overcoming the limitations of motion sensor models by considering dendritic computations
海马体中人口活动的稀疏性在三突触回路和背腹轴上与任务无关。	Lee, J. Q.	PDF	N/A	Sparsity of population activity in the hippocampus is task-invariant across the trisynaptic circuit and dorsoventral axis
在斑马鱼胚胎中，快肌纤维的生长与Mylpf剂量的增加成比例	Adekeye, T. E.	PDF	N/A	Fast-twitch myofibrils grow in proportion to Mylpf dosage in the zebrafish embryo
机器学习时代的整合建模：HADDOCK策略在CAPRI第47至55轮中的总结	Reys, V.	PDF	N/A	Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55
用于结构系统发育学的通用替换矩阵。	Garg, S. G.	PDF	N/A	A general substitution matrix for structural phylogenetics.
探索同步的边缘：在行为中的猴子中，皮层活动短暂地滑入慢波	Pazienti, A.	PDF	N/A	Probing The Edge Of Synchronization: Cortical Activity Transiently Slips Into Slow Waves In Behaving Monkeys
从DNA序列预测和功能解析染色体间基因组结构的双胞胎方法	Jha, A.	PDF	N/A	Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC
来自精神分裂症个体的hiPSC衍生的星形胶质细胞促进了类似小胶质细胞的吞噬作用和趋化性的改变	Cardozo, P. L.	PDF	N/A	hiPSC-derived astrocytes from individuals with schizophrenia promote alterations in phagocytosis and chemotaxis of microglial-like cells
使用神经网络解决巴布亚新几内亚人口的非洲起源事件	Mondal, M.	PDF	N/A	Resolving out of Africa event for Papua New Guinean population using neural network
BCR交联有选择性地抑制IgE类别转换重组	Wade-Vallance, A. K.	PDF	N/A	BCR ligation selectively inhibits IgE class switch recombination
寄生传播时间选择塑造了宿主冈比亚按蚊的转录反应，并提示免疫逃避	Silva, L. M.	PDF	N/A	Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion
scooby：在单细胞分辨率下从DNA序列建模多模态基因组特征	Hingerl, J. C.	PDF	N/A	scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution
环节动物组蛋白基染色质调控的演化与发展动力	Martin-Zamora, F. M.	PDF	N/A	The evolution and developmental dynamics of histone-based chromatin regulation in Annelida
地下动物的隐花色素-1（Cryptochrome-1）中反复出现的突变，改变了行为和分子层面的昼夜节律。	Swaminathan, A.	PDF	N/A	A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms
苜蓿（Medicago truncatula）中的CORYNE基因调控花序分生组织分支、营养信号传递以及丛枝菌根共生关系	Orosz, J.	PDF	N/A	Medicago truncatula CORYNE regulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis
田间作物转录组模型通过在系统控制的环境中的测量得到了增强	Hashida, Y.	PDF	N/A	Field-crop transcriptome models are enhanced by measurements in systematically controlled environments
多病虫抗性番茄品系对白粉虱传播病毒TYLCV积累的响应	Prabhakar, S. S.	PDF	N/A	The response of multi-disease and insect-resistant tomato lines to the accumulation of TYLCV, a whitefly-transmitted virus
PEBP1 增强线粒体功能障碍引发的整合应激反应	Cheng, L.	PDF	N/A	PEBP1 amplifies mitochondrial dysfunction induced integrated stress response
定义不同代谢条件下人类脂肪组织的血管龛	AlZaim, I.	PDF	N/A	Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions
LINE1促进核内区室化以抑制胚胎干细胞中的8细胞状态	Zhang, J.	PDF	N/A	LINE1 promotes nuclear compartmentalization to repress the 8-cell state in embryonic stem cells
BEDMS：一种基因组区域属性元数据标准化工具	Tambe, S.	PDF	N/A	BEDMS: A metadata standardizer for genomic regionattributes
矮牵牛杂交种的染色体水平基因组组装与注释	Saei, A.	PDF	N/A	Chromosome-level Genome Assembly and Annotation of Petunia hybrida
早期生活不可预测性对青少年海马和杏仁核对新奇刺激反应的性别特异性影响	Davis, E. P.	PDF	N/A	Sex-specific effects of early life unpredictability on hippocampal and amygdala responses to novelty in adolescents
不饱和脂质作为控制穴样内陷形成和解体的关键因素	Wu, Y.	PDF	N/A	Unsaturated lipids as key control points for caveola formation and disassembly
瞬时Notch激活将多能干细胞衍生的心肌细胞转化为浦肯野纤维命运	Gonzalez, D. M.	PDF	N/A	Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate
动态系统理论指导下的细胞分化景观学习	Howe, A. E. S.	PDF	N/A	Dynamical systems theory informed learning of cellular differentiation landscapes
物种共现模型的样本量考虑。	Cowans, A.	PDF	N/A	Sample size considerations for species co-occurrence models.
温度与资源之间的相互作用如何从种群扩展到群落	Kremer, C. T.	PDF	N/A	How interactions between temperature and resources scale from populations to communities
严格（在）验证生态模型	Song, C.	PDF	N/A	Rigorous (in)validation of ecological models
杂合缺失对拟南芥表型变化及剂量补偿的影响	Ikoma, T.	PDF	N/A	Effect of heterozygous deletions on phenotypic changes and dosage compensation in Arabidopsis thaliana
比较泛基因组学揭示了临床相关成员在镰刀菌属物种复合体中的不同适应性	Brassington, P. J.	PDF	N/A	Comparative pan-genomics reveals divergent adaptations in clinically-relevant members of the Fusarium solani species complex
探索单细胞数据中的群体特异性技术变异模式	Zhou, Y.	PDF	N/A	Exploring group-specific technical variation patterns of single-cell data
PoreVision：一种用于提升扫描电镜孔隙分析效率和准确性的程序	Olevsky, L. M.	PDF	N/A	PoreVision: A Program for Enhancing Efficiency and Accuracy in SEM Pore Analyses
DiffPaSS - 使用软分数进行高性能可微蛋白质序列配对	Lupo, U.	PDF	N/A	DiffPaSS - High-performance differentiable pairing of protein sequences using soft scores
通过表征学习和稀疏模型发现探索生物系统的控制方程	Sadria, M.	PDF	N/A	Discovering Governing Equations of Biological Systems through Representation Learning and Sparse Model Discovery
GuaCAMOLE：GC偏倚感知估计提高了宏基因组物种丰度的准确性	Holcik, L.	PDF	N/A	GuaCAMOLE: GC-bias aware estimation improves the accuracy of metagenomic species abundances
揭示半乳糖凝集素-1与脂质膜结合的GM1特异性	Scollo, F.	PDF	N/A	Unraveling the GM1 specificity of Galectin-1 binding to lipid membranes
扩展自动化多构象配体建模至大环化合物和片段	Flowers, J.	PDF	N/A	Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments
没有基因振荡器或外部驱动的生物振荡	Vandenbroucke, V.	PDF	N/A	Biological oscillations without genetic oscillator or external forcing
一种新型方法用于在单细胞分辨率下表征细胞间相互作用，揭示了感染期间血液T细胞-单核细胞复合物的独特特征	Kang, N.	PDF	N/A	A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes during infection
FcγR和CD9依赖的丘脑突触吞噬小胶质细胞驱动皮层脑损伤后的认知障碍	Matoba, K.	PDF	N/A	FcγR- and CD9-dependent synapse engulfing microglia in the thalamus drives cognitive impairment following cortical brain injury
溶酶体LRRC8复合物调节溶酶体pH值、形态及全身葡萄糖代谢	Kumar, A.	PDF	N/A	Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism
磷脂酶D的辅助域调控其在果蝇光感受器中的定位和活性	Naik, A.	PDF	N/A	The accessory domains of Phospholipase D regulate its localization and activity in Drosophila photoreceptors
线粒体移植：适应性生物增强	Lu, X.	PDF	N/A	Mitochondrial Transplantation: Adaptive Bio-enhancement
在裂殖酵母中，细胞质内的扩散随着细胞大小的增加而增加。	Tan, C.	PDF	N/A	Intracellular diffusion in the cytoplasm increases with cell size in fission yeast
幼稚多能性退出包含一个由脂质代谢引发的基因组完整性检查点。	de Souza, R. A.	PDF	N/A	The exit of naïve pluripotency contains a lipid metabolism-induced checkpoint for genome integrity.
内共生体以温度依赖的方式影响瓢虫对蚜虫的捕食率	Thomsen, K. B.	PDF	N/A	Endosymbionts impact ladybird predation rates of aphids in a temperature-dependent manner
日均温度可以比速率累加更好地预测疟疾传播的热限。	Shocket, M. S.	PDF	N/A	Mean daily temperatures can predict the thermal limits of malaria transmission better than rate summation
传统品种环境数据在气候适应型玉米育种中的应用	Li, F.	PDF	N/A	The utility of environmental data from traditionalvarieties for climate-adaptive maize breeding
不同衬纸材料和浸液对埃及伊蚊（双翅目：蚊科）雌蚊产卵偏好的影响	Momen, M.	PDF	N/A	Effect of different lining paper materials and infusions on oviposition preference of Aedes aegypti (Diptera: Culicidae) gravid mosquitoes
Msp1介导的脂质双层中底物提取的能量需求和机制可塑性	Smith, B.	PDF	N/A	Energetic requirements and mechanistic plasticity in Msp1-mediated substrate extraction from lipid bilayers
SMART MRS：一种用于GABA编辑磁共振波谱（MRS）的模拟MEGA-PRESS伪影工具箱	Bugler, H.	PDF	N/A	SMART MRS: A Simulated MEGA-PRESS Artifacts Toolbox for GABA-edited MRS
人类NDPK六聚体结构、稳定性和相互作用的动态建模	Lim, Y. Y.	PDF	N/A	Modelling dynamics of human NDPK hexamer structure, stability and interactions
用于监测Cas9核酸内切酶活性的固态纳米孔实时检测	Chau, C. C.	PDF	N/A	Solid-State Nanopore Real Time Assay for Monitoring Cas9 Endonuclease Reactivity
浓缩LiCl水溶液中DNA的性质表明向C-DNA的转变	Mazur, A.	PDF	N/A	Properties of DNA in concentrated aqueous solutions of LiCl suggest transition to C-DNA
宫内生长受限对发育中的胰腺免疫系统的影响	Golden, T. N.	PDF	N/A	The effect of intrauterine growth restriction on the developing pancreatic immune system
CanDrivR-CS：一种用于区分复发性和罕见变异的癌症特异性机器学习框架	Francis, A.	PDF	N/A	CanDrivR-CS: A Cancer-Specific Machine Learning Framework for Distinguishing Recurrent and Rare Variants
TBX15调控脂肪组织中免疫应答基因网络，并改变杂合敲除小鼠的脂肪质量和脂肪库重量	Zolkiewski, L.	PDF	N/A	TBX15 regulates a network of immune response genes in adipose tissue and alters fat mass and depot weight in heterozygous knockout mice
一种一步法协议，用于制备适用于原位活细胞应用和超分辨率成像的不透光荧光HaloTag底物	Rossmann, K.	PDF	N/A	A one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging
PointTree：单神经元长程轴突投射的自动精确重建	Cai, L.	PDF	N/A	PointTree: Automatic and accurate reconstruction of long-range axonal projections of single-neuron
弥合秀丽隐杆线虫的连接组与全脑活动之间的差距	Creamer, M. S.	PDF	N/A	Bridging the gap between the connectome and whole-brain activity in C. elegans
构建小鼠大脑树突微环境的图谱有助于发现解剖布局、投射目标和神经元转录组特征之间的潜在关联。	Liu, Y.	PDF	N/A	Constructing a Mouse Brain Atlas of Dendritic Microenvironments Helps Discover Hidden Associations Between Anatomical Layout, Projection Targets and Transcriptomic Profiles of Neurons
Tau P301S转基因小鼠出现步态和眼球运动障碍，类似于进行性核上性麻痹	Creed, R. B.	PDF	N/A	Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy
低强度聚焦超声参数在人类神经调控中的研究	Ennasr, A.	PDF	N/A	Examination of low-intensity focused ultrasound parameters for human neuromodulation
视觉体验评估工具：一种用于量化视觉体验的近视研究仪器	Sullivan, D.	PDF	N/A	The Visual Experience Evaluation Tool: A Myopia Research Instrument for Quantifying Visual Experience
SAPAP3小鼠模型在强迫症发病前的特征：行为、神经可塑性及裸盖菇素治疗	Lazar, M.	PDF	N/A	Premorbid Characteristics of the SAPAP3-Mouse Model of Obsessive-Compulsive Disorder: Behavior, Neuroplasticity, and Psilocybin Treatment
TWINKLE：一款用于教学和研究的开源双光子显微镜	Schottdorf, M.	PDF	N/A	TWINKLE: An open-source two-photon microscope for teaching and research
鼠标爪：逆转翻译FINGER多模态生活方式干预增强了成年野生型雌性小鼠的突触可塑性和认知能力	Alanko, V.	PDF	N/A	Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice
成年神经发生和焦虑的自然变异预测近交系小鼠的等级地位	Grieco, F.	PDF	N/A	Natural variations of adult neurogenesis and anxiety predict hierarchical status of inbred mice
PHluorin-偶联的次级纳米抗体作为测量突触小泡胞外和胞内吞吐的工具	Georgiev, S. V.	PDF	N/A	PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exo- and endocytosis
不同体型动物的前馈和反馈控制性能受感觉运动延迟和肌肉力量能力限制的影响	Mohamed Thangal, S. N.	PDF	N/A	Effects of sensorimotor delays and muscle force capacity limits on the performance of feedforward and feedback control in animals of different sizes
嗅觉和三叉神经途径的HSV-1中枢神经系统感染与区域性小胶质细胞异质性	Niemeyer, C.	PDF	N/A	Olfactory and Trigeminal Routes of HSV-1 CNS Infection with Regional Microglial Heterogeneity
在语言产生和理解过程中，额叶-颞叶皮层中与语音声音特异性一致的脑信号。	Dmitrieva, X.	PDF	N/A	Congruent brain signatures specific to speech sounds in fronto-temporal cortex during language production and understanding.
女性一生中的全脑动态与激素变化：从生殖阶段到更年期过渡及之后	Escrichs, A.	PDF	N/A	Whole-brain dynamics and hormonal shifts throughout women's lifespan: From reproductive stages to menopausal transition and beyond
新生小鼠在出现觅食和饮水行为之前，饥饿和口渴的神经表征具有显著差异	Wang, D. C.	PDF	N/A	Distinct Neural Representations of Hunger and Thirst in Neonatal Mice before the Emergence of Food- and Water-seeking Behaviors
创伤性脑损伤加剧了酒精摄入和神经炎症，同时伴随着认知功能和胆碱能活性的下降。	Gangal, H.	PDF	N/A	Traumatic Brain Injury Exacerbates Alcohol Consumption and Neuroinflammation with Decline in Cognition and Cholinergic Activity
音乐才能调节皮层（而非脑干）对音乐三和弦处理中注意力的影响	MacLean, J.	PDF	N/A	Musicianship modulates cortical (but not brainstem) effects of attention on processing musical triads
广泛的大脑活动增加与意识受损的额叶癫痫发作有关	Salardini, E.	PDF	N/A	Widespread brain activity increases in frontal lobe seizures with impaired consciousness
神经几何学有效地表示了灵长类基底神经节中价值和模态的抽象形式。	Kim, H. F.	PDF	N/A	Neural geometry efficiently representing abstract form of value and modality in the primate basal ganglia
神经几何学有效地表示了灵长类基底神经节中价值和模态的抽象形式。	Hwang, S.-H.	PDF	N/A	Neural geometry efficiently representing abstract form of value and modality in the primate basal ganglia
经济选择中神经编码的理性注意力不足	Fine, J. M.	PDF	N/A	Rational inattention in neural coding for economic choice
人类胚胎类器官形态空间的可解释图谱揭示了原肠胚形成失败模式并预测了致畸物	Rufo, J.	PDF	N/A	An explainable map of human gastruloid morphospace reveals gastrulation failure modes and predicts teratogens
访客对灵长类动物救助中心黑猩猩（Pan troglodyte）行为的影响	Maurer, S.	PDF	N/A	Visitor effect on the behavior of chimpanzees (pan troglodyte) at a primate rescue center
内质网应激转录因子Luman/CREB3通过激活未折叠蛋白反应和胆固醇生物合成途径，是施万细胞存活和髓鞘形成能力的新型调控因子。	Verge, V. M. K.	PDF	N/A	The ER stress transcription factor Luman/CREB3 is a novel regulator of Schwann cell survival and myelinating capacity through the activation of the unfolded protein response and cholesterol biosynthesis pathways
胆碱能神经元活动通过毒蕈碱信号传导促进弥漫性中线胶质瘤的生长	Monje, M.	PDF	N/A	Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling
神经选择性的系统性变化反映了类别诊断维度所获得的重要性。	Luthra, S.	PDF	N/A	Systematic changes in neural selectivity reflect the acquired salience of category-diagnostic dimensions
产后环境富集可纠正成年小鼠早期逆境暴露导致的神经周围网形成缺陷及反转学习障碍	Jamwal, S.	PDF	N/A	Postnatal Enrichment Corrects Deficits in Perineuronal Net Formation and Reversal Learning in Adult Mice Exposed to Early Adversity
利用连续时间转移熵估计器推断脉冲神经元的有效网络	Shorten, D.	PDF	N/A	Inferring Effective Networks of Spiking Neurons Using a Continuous-Time Estimator of Transfer Entropy
AKT介导的TSC2磷酸化调控刺激和组织特异性mTORC1信号传导及器官生长	Cormerais, Y.	PDF	N/A	AKT-mediated phosphorylation of TSC2 controls stimulus and tissue-specific mTORC1 signaling and organ growth
Bnip3lb驱动的线粒体自噬维持了胚胎造血干细胞池的扩增	Meader, E.	PDF	N/A	Bnip3lb-driven mitophagy sustains expansion of the embryonic hematopoietic stem cell pool
间充质-上皮转变减少了肿瘤球体的增殖，但增加了免疫逃逸	Dimari, G.	PDF	N/A	Mesenchymal-epithelial transition reduces proliferation but increases immune evasion in tumor spheroids
脱嘧啶/脱嘌呤核酸内切酶2（APEX2/APE2）在人胚胎干细胞中对TERT的高效表达是必需的。	Stern, J. L.	PDF	N/A	Apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2/APE2) is required for efficient expression of TERT in human embryonic stem cells.
内核膜磷酸酶复合物对TGF-β/SMAD信号的抑制作用	Ji, Z.	PDF	N/A	Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex
细胞信号通过Rac和WAVE介导的机制，将Arp2/3复合物从基底侧招募到顶端，从而促进顶端收缩。	Zhang, P.	PDF	N/A	Cell signaling facilitates apical constriction by basolaterally recruiting Arp2/3 via Rac and WAVE
空间多组学揭示胰腺癌免疫治疗病理反应者中与三级淋巴结构相关的肿瘤内体液免疫微环境	Sidiropoulos, D. N.	PDF	N/A	Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer immunotherapy pathologic responders
机器学习驱动的SARS-CoV-2适应性景观模拟	Durumeric, A. E. P.	PDF	N/A	Machine Learning Driven Simulations of SARS-CoV-2 Fitness Landscape
肠道微生物群昼夜振荡节律的丧失与动脉粥样硬化的进展相关	Zhang, H.	PDF	N/A	Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Progression of Atherosclerosis
在植物体内转座子测序用于鉴定Xylella fastidiosa中的毒力基因	Burbank, L. P.	PDF	N/A	In planta transposon sequencing for virulence gene identification in Xylella fastidiosa
肠球菌属粪肠球菌菌株中β-内酰胺耐药性的进化轨迹	Ugalde-Silva, P.	PDF	N/A	Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains
在考古牙齿结石中鉴定古代抗生素抗性基因	Standeven, F.	PDF	N/A	Identifying ancient antibiotic resistance genes in archaeological dental calculus
在铜绿假单胞菌拮抗作用下，脓肿分枝杆菌的持续存在	Gupta, R.	PDF	N/A	Mycobacterium abscessus persistence in the face of Pseudomonas aeruginosa antagonism
胞外多糖聚N-乙酰葡萄糖胺（PNAG）在体内覆盖肺炎克雷伯菌。	Bradshaw, J.	PDF	N/A	The exopolysaccharide Poly-N-Acetyl-Glucosamine (PNAG) coats Klebsiella pneumoniae in vivo
一种膜结合的传送带控制着细菌第9型分泌系统的旋转方向	Shrivastava, A.	PDF	N/A	A membrane-associated conveyor belt controls the rotational direction of the bacterial type 9 secretion system
与炎症性肠病相关的肠埃希菌菌株侵袭性的遗传和微生物分析	Kim, J.	PDF	N/A	Genetic and microbial analysis of invasiveness for Escherichia coli strains associated with inflammatory bowel disease
群体感应通过依赖和不依赖于第六型分泌系统的机制调控霍乱弧菌中的平行细胞死亡途径	Mashruwala, A. A.	PDF	N/A	Quorum sensing orchestrates parallel cell death pathways in Vibrio cholerae via Type 6 secretion dependent and independent mechanisms
粪便滤液转移对坏死性小肠结肠炎的防护作用需要供体活病毒组的存在	Spiegelhauer, M. R.	PDF	N/A	Protection against necrotizing enterocolitis by fecal filtrate transfer requires an active donor virome
鼻内接种的雪貂在急性期和急性后期阶段，SARS-CoV-2的神经侵袭性和神经毒力潜能	Benavides, F. F. W.	PDF	N/A	Neuroinvasive and neurovirulent potential of SARS-CoV-2 in the acute and post-acute phase of intranasally inoculated ferrets
利用工程改造的甲烷嗜甲基菌（Methanosarcina acetivorans）从一碳化合物中生产倍半萜类化合物巴索贝内烯（bisabolene）	Mentrup, A.	PDF	N/A	Production of the sesquiterpene bisabolene from one-carbon compounds in an engineered Methanosarcina acetivorans
Pythia：非随机DNA修复使得CRISPR/Cas9整合和基因编辑具有可预测性	Naert, T.	PDF	N/A	Pythia: Non-random DNA repair allows predictable CRISPR/Cas9 integration and gene editing
TNFSF13 不足会破坏人类结肠上皮细胞介导的 B 细胞分化	Ma, X.	PDF	N/A	TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation
SGLT2抑制剂通过非CaMKII依赖的机制，对糖尿病心肌病和心房颤动具有保护作用。	Severino, A.	PDF	N/A	SGLT2 inhibitors protect against diabetic cardiomyopathy and atrial fibrillation through a CaMKII independent mechanism
MTALTCO1：一种由线粒体DNA编码的259个氨基酸长的替代蛋白，挑战了传统线粒体基因组学的理解。	Robitaille, F.	PDF	N/A	MTALTCO1: a 259 amino acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics.
蛋白质语言模型：规模化是必要的吗？	Fournier, Q.	PDF	N/A	Protein Language Models: Is Scaling Necessary?
百日咳毒素抗体中和作用的结构基础	Goldsmith, J. A.	PDF	N/A	Structural Basis for Antibody Neutralization of Pertussis Toxin
在阿尔茨海默病中，Tau蛋白及其他聚集蛋白中发现脱水氨基酸及其交联结构	Markovich, S. W.	PDF	N/A	Discovery of dehydroamino acids and their crosslinks in Tau and other aggregating proteins of Alzheimers disease
一种综合建模方法用于线粒体嵴	Brown, C. M.	PDF	N/A	An integrative modelling approach to the mitochondrial cristae
肠道微生物组时代的人类非靶向代谢组学：乙醇与甲醇	Zuffa, S.	PDF	N/A	Human untargeted metabolomics in the gut microbiome era: ethanol vs methanol
肝源性醛糖还原酶驱动类似Warburg效应的代谢重编程，促进胰岛素抵抗、脂肪肝和肥胖	Song, D.	PDF	N/A	Hepatic aldose reductase drives a Warburg effect-like metabolic reprogramming to promote insulin resistance, fatty liver and obesity
一种用于Caldimonas thermodepolymerans的初始基因编辑工具集，这是首个嗜热聚羟基烷酸生产模型的代表。	Grybchuk-Ieremenko, A.	PDF	N/A	An initial genome editing toolset for Caldimonas thermodepolymerans, the first model of thermophilic polyhydroxyalkanoates producer
准确的超大规模基因组集多序列比对	Lai, X.	PDF	N/A	Accurate Multiple Sequence Alignment of Ultramassive Genome Sets
设计一种基于细胞内适配体的荧光生物传感器，用于追踪大肠杆菌的负担	Grob, A.	PDF	N/A	Design of an intracellular aptamer-based fluorescent biosensor to track burden in E. coli
建筑给排水系统影响饮用水微生物群的微多样性和群落构建。	He, H.	PDF	N/A	Building plumbing influences the microdiversity and community assembly of the drinking water microbiome.
针对宿主转录因子HSF1可阻止人巨细胞病毒在体外和体内的复制	Biswas, J.	PDF	N/A	Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo
CLCC1促进疱疹病毒核输出过程中的膜融合。	Dai, B.	PDF	N/A	CLCC1 promotes membrane fusion during herpesvirus nuclear egress.
间歇性高频有氧-缺氧循环扰动提高废水处理过程中N2O还原酶活性	Zhou, X.	PDF	N/A	Intermittent Perturbation with High-Frequency Aerobic-Anoxic Cycling Enhances N2O Reductase Activity during Wastewater Treatment
铜绿假单胞菌PAO1的b型鞭毛蛋白糖基结构解析	Hensbergen, P. J.	PDF	N/A	Elucidation of the glycan structure of the b-type flagellin of Pseudomonas aeruginosa PAO1
百日咳博德特氏菌的一种新型粘附素是其侵入上皮细胞的关键	Gollan, M.	PDF	N/A	A Novel Adhesin of B. pertussis is Key to Colonisation of Epithelial Cells
CHAMP1复合体指导异染色质组装并促进同源定向DNA修复。	D'Andrea, A. D.	PDF	N/A	CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair
基于CRISPR的转录激活系统中激活子表达的细胞毒性	Maddineni, A.	PDF	N/A	Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems
适用于原代干细胞多模式CRISPR基因编辑的多功能细胞穿透肽	Graham, J. P.	PDF	N/A	Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
PDZ介导的底物招募是PP1-Neurabin特异性去磷酸化4E-BP1的主要决定因素。	Fedoryshchak, R. O.	PDF	N/A	PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1dephosphorylation by PP1-Neurabin
海马体对替代可能性的表征是灵活生成的，以满足认知需求。	Comrie, A. E.	PDF	N/A	Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands
母子二元互动塑造了儿童的社会大脑和心智理论	Li, L.	PDF	N/A	Mother-child dyadic interactions shape children's social brain and theory of mind
肾上腺素能信号调控星形胶质细胞对神经递质的反应性及对神经活动的控制	Guttenplan, K. A.	PDF	N/A	Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity
主要精神疾病的人类神经发育模型中GABA能神经元失调	Guo, Z.	PDF	N/A	GABAergic neuron dysregulation in a human neurodevelopmental model for major psychiatric disorders
罗马殖民与迁徙时期对伊比利亚半岛人口的差异性影响。	Carrion, P.	PDF	N/A	Disparate demographic impacts of the Roman Colonization and the Migration Period in the Iberian Peninsula.
# BioRxiv 2024-09-22 Papers

标题	作者	PDF链接	代码仓库	Title
传导机制在冷温度下对不同外周器官的鼠三叉神经和迷走神经节神经元的影响	Gers-Barlag, K.	PDF	N/A	Transduction mechanisms for cold temperature in mouse trigeminal and vagal ganglion neurons innervating different peripheral organs
从组学数据集中数据驱动的提取人类激酶-底物关系	Maier, B. D.	PDF	N/A	Data-driven extraction of human kinase-substrate relationships from omics datasets
利用合成聚合物探究脂质力机制	Jacobs, M. L.	PDF	N/A	Probing the force-from-lipid mechanism with synthetic polymers
自我信念的力量：成长型思维通过中皮层功能共激活和动态重构促进认知发展	Zhao, Y.	PDF	N/A	Power of self-belief: Growth mindset fosters cognitive development via mesocortical functional coactivation and dynamic reconfiguration
多巴胺神经元在果蝇嗅觉记忆中具有不同的、急性的功能，驱动吸引和厌恶	Mohammad, F.	PDF	N/A	Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion
有齿鲸基因的分子进化揭示了在不同环境中回声定位的适应性	Magpali, L.	PDF	N/A	Molecular evolution of toothed whale genes reveals adaptations to echolocating in different environments
植物乳杆菌和八角提取物抑制单纯疱疹病毒和水疱性口炎病毒增殖与诱导MX基因表达相关	Elebeedy, D.	PDF	N/A	Inhibition of Herpes simplex virus and Vesicular stomatitis virus Proliferation by Lactiplantibacillus planterum and star anise Extract Is Associated with Induction of MX gene expression
Spanve：一种用于在大规模空间转录组数据中检测下游友好型空间变异基因的统计方法	Cai, G.	PDF	N/A	Spanve: A Statistical Method for Detecting Downstream-Friendly Spatially Variable Genes in Large-Scale Spatial Transcriptomic Data
自噬体膜连接的重构揭示了Atg11结合膜的能力对线粒体自噬的重要性。	Andhare, D.	PDF	N/A	Reconstitution of autophagosomal membrane tethering reveals that the ability of Atg11 to bind membranes is important for mitophagy.
所有CDKN2A错义变体的功能表征及其与致病性计算机模型的比较	Kimura, H.	PDF	N/A	Functional characterization of all CDKN2A missense variants and comparison to in silico models of pathogenicity
使用Neuropixels探针在猕猴初级视觉皮层中进行高分辨率层级识别	Zhang, L. A.	PDF	N/A	High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes
加压素1a受体拮抗剂破坏了大嘴乌鸦通过三重共居形成的雄性间亲和关系	Seguchi, A.	PDF	N/A	Vasopressin 1a receptor antagonist disrupts male-male affiliative relationships formed by triadic cohabitation in large-billed crows
磁共振经济学：在全脑关联研究中平衡样本量与扫描时长	Ooi, L. Q. R.	PDF	N/A	MRI economics: Balancing sample size and scan duration in brain wide association studies
线粒体呼吸图谱揭示了线粒体功能在性别和年龄上的差异变化	Sarver, D. C.	PDF	N/A	Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age
内源性过氧化氢正向调节肠道衍生肽的分泌，在秀丽隐杆线虫的氧化应激反应中增强神经内分泌作用	Jia, Q.	PDF	N/A	Endogenous hydrogen peroxide positively regulates secretion of a gut-derived peptide in neuroendocrine potentiation of the oxidative stress response in C. elegans
使用单细胞转录组学对细胞周期状态和类似静止的G0状态进行分类	O'Connor, S. A.	PDF	N/A	Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomics
空间转录组学在骨力学生物学中的应用：探索空间组学时代骨折愈合的力学调控。	Mathavan, N.	PDF	N/A	Spatial Transcriptomics in Bone Mechanomics: Exploring the Mechanoregulation of Fracture Healing in the Era of Spatial Omics.
人类侧隔核神经元的转录组特征分析揭示了跨物种保守和分化的标记基因	Phillips, R. A.	PDF	N/A	Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species
将代谢建模与成像结合用于筛选结直肠癌的治疗靶点	Tavakoli, N.	PDF	N/A	Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer
系统性遗传表征人类PKR激酶结构域突显其功能可塑性，以逃避痘病毒底物模拟	Chambers, M. J.	PDF	N/A	Systematic genetic characterization of the human PKR kinase domain highlights its functional malleability to escape a poxvirus substrate mimic
由于Vsx2位点上的LacZ敲入/敲出等位基因，导致小眼症和视网膜发育紊乱	Napoli, F. R.	PDF	N/A	Microphthalmia and disrupted retinal development due to a LacZ knock-in/knock-out allele at the Vsx2 locus
去卷积化的甲基化图谱可区分密切相关的黑色素细胞痣	Aldea, D.	PDF	N/A	Deconvoluted methylation profiles discriminate between closely related melanocytic nevi
植物交配系统的进化动力学：研究“有趣”植物繁殖系统的偏见可能会适得其反	Meyer, E. M.	PDF	N/A	The evolutionary dynamics of plant mating systems: how bias for studying 'interesting' plant reproductive systems could backfire
人类尿液微生物群的短期和中期时间变异性：一项观察性队列研究	Tlaskal, V.	PDF	N/A	Short- and mid-term temporal variability of the human urinary microbiota: an observational cohort study
通过超结构扩展显微镜技术，绘制犬视网膜感光细胞纤毛和杯状突起的蛋白质分布图	Takahashi, K.	PDF	N/A	Mapping protein distribution in the canine photoreceptor sensory cilium and calyceal processes by ultrastructure expansion microscopy
VirID：超越病毒发现——综合平台助力全面RNA病毒特征研究	Yang, Z.	PDF	N/A	VirID: Beyond Virus Discovery - An Integrated Platform for Comprehensive RNA Virus Characterization
cGAS-STING通路在急性缺血诱导的骨髓中性粒细胞生成和中性粒细胞激活中起关键作用	Zhu, J.	PDF	N/A	The cGAS-STING Pathway Is Essential in Acute Ischemia-Induced Neutropoiesis and Neutrophil Priming in the Bone Marrow
通过巨胞饮作用减少顶端大小可缓解组织拥挤	Bresteau, E.	PDF	N/A	Apical Size Reduction by Macropinocytosis Alleviates Tissue Crowding
生长率驱动的建模揭示了表型适应如何驱动BRAFV600E突变型黑色素瘤的药物抗性	Hamis, S.	PDF	N/A	Growth rate-driven modelling reveals how phenotypic adaptation drives drug resistance in BRAFV600E-mutant melanoma
由RhoA特异性GEF ARHGEF17介导的反馈调节调控肌动肌球蛋白网络的解聚	Rao, V.	PDF	N/A	Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly
微生物种群几乎从未按逻辑增长，也从未按次线性增长。	Camacho-Mateu, J.	PDF	N/A	Microbial populations hardly ever grow logistically and never sublinearly
将条形码测序技术应用于提高恶性疟原虫遗传筛选的通量和复杂性	Muhwezi, A.	PDF	N/A	Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening
通过血管壁龛的神经内分泌调控果蝇肠道再生。	Medina, A.	PDF	N/A	Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila.
通过SpaHDmap对空间转录组数据进行可解释的高分辨率降维	Tang, J.	PDF	N/A	Interpretable high-resolution dimension reduction of spatial transcriptomics data by SpaHDmap
针对癌症相关糖基化进行胃肠道和妇科癌症的过继T细胞治疗	Zingg, A.	PDF	N/A	Targeting cancer-associated glycosylation for adoptive T cell therapy of gastro-intestinal and gynecological cancers
利用活体叶片切片成像技术分析C4植物叶肉细胞中依赖于束鞘细胞的叶绿体运动	Kato, Y.	PDF	N/A	Bundle sheath cell-dependent chloroplast movement in mesophyll cells of C4 plants analyzed using live leaf-section imaging
使用质粒分析服务进行高效且成本效益高的长读长扩增子测序：应用于日本牵牛花中的转座子插入等位基因	Nakagawa, S.	PDF	N/A	Labor- and cost-effective long-read amplicon sequencing using a plasmid analysis service: Application to transposon-inserted alleles in Japanese morning glory
聚焦镓离子束的生物体积电子显微镜依赖于在断面形成辐射抗性富镓层。	Yang, Z.	PDF	N/A	Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face
BrainUnit：将物理单位融入高性能AI驱动的科学计算	Wang, C.	PDF	N/A	BrainUnit: Integrating Physical Units into High-Performance AI-Driven Scientific Computing
出生后前六个月大脑网络的空间发展	Seraji, M.	PDF	N/A	Spatial Development of Brain Networks During The First Six Postnatal Months
白腿虾养殖生产力的微生物组决定因素	Shan, X.	PDF	N/A	Microbiome determinants of productivity in whiteleg shrimp aquaculture
授粉者Eristalis tenax中固有花卉偏好的消失	Rajan, D. H.	PDF	N/A	Extinction of innate floral preferences in the pollinator Eristalis tenax
从头设计的别构可调蛋白纤维的成核限制组装与极性生长	Shen, H.	PDF	N/A	Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament
使用神经网络解决巴布亚新几内亚人口的“走出非洲”事件	Mondal, M.	PDF	N/A	Resolving out of Africa event for Papua New Guinean population using neural network
高风险神经精神性拷贝数变异与人类脑细胞中趋同的转录组变化相关	Dugan, G.	PDF	N/A	High-risk neuropsychiatric copy number variants are associated with convergent transcriptomic changes in human brain cells
miR-92a目标RBFOX2的过早上调劫持了PTBP剪接并损害了皮层神经元的分化。	Weissbach, S.	PDF	N/A	Premature upregulation of miR-92a's target RBFOX2 hijacks PTBP splicing and impairs cortical neuronal differentiation.
从一百万个单倍体基因组中估算人口统计学和突变率	Schraiber, J. G.	PDF	N/A	Estimation of demography and mutation rates from one million haploid genomes
在恒定条件下实验室小鼠发情周期的季节性变化	Reichard, T. M.	PDF	N/A	Seasonality of the estrus cycle in laboratory mice under constant conditions
在编码稀疏基因组的物种中，使用两步法从群体基因组数据推断人口统计和选择历史：以人类数据为例的应用	Soni, V.	PDF	N/A	Inferring demographic and selective histories from population genomic data using a two-step approach in species with coding-sparse genomes: an application to human data
第15组苗前除草剂对除草剂抗性和非抗性黑麦草的生长、表皮蜡质成分及脂肪酸代谢产生不同影响	Blyth, H. R.	PDF	N/A	Group 15 Pre-emergent Herbicides Differentially Effect Plant Growth, Cuticular Wax Composition, and Fatty Acid Metabolism in Herbicide-Resistant and Herbicide-naïve Blackgrass
调节β-连环蛋白对促进巨噬细胞中WNT表达和减轻肠道损伤具有重要意义。	Chugh, R. M.	PDF	N/A	Modulation of β-Catenin is important to promote WNT expression in macrophages and mitigate intestinal injury
表观遗传调控网络的扩展和多样化奠定了陆地植物进化过程中重大转变的基础	Petroll, R.	PDF	N/A	The expansion and diversification of epigenetic regulatory networks underpins major transitions in the evolution of land plants
广谱反应性抗VHH抗体用于表征、阻断或激活基于纳米抗体的CAR-T细胞	McComb, S.	PDF	N/A	Broadly Reactive Anti-VHH Antibodies for Characterizing, Blocking, or Activating Nanobody-Based CAR-T Cells
自然杀伤细胞功能在妊娠和肿瘤进展过程中受TGF-β信号通路的调控。	Yalin, A.	PDF	N/A	Natural killer cell function is regulated by TGF-β signaling in pregnancy and tumor progression
TSTA：基于线程和SIMD的梯形成对/多序列比对方法	Peiyu, Z.	PDF	N/A	TSTA: Thread and SIMD-Based Trapezoidal Pairwise/Multiple Sequence Alignment Method
乳腺癌细胞系中非组蛋白赖氨酸甲基化位点及赖氨酸去甲基化酶的定量分析	Berryhill, C. A.	PDF	N/A	Quantitative analysis of non-histone lysine methylation sites and lysine demethylases in breast cancer cell lines
单核细胞衍生的细胞而非小胶质细胞在神经炎症中引起氧化组织损伤	Villar-Vesga, J.	PDF	N/A	Monocyte-derived cells but not Microglia cause Oxidative Tissue Damage in Neuroinflammation
发育期和成年期饮食的加性和情境依赖性效应及其在杂交果蝇群体中对生活史特征及其关联的影响	Chandrakanth, M.	PDF	N/A	Additive and context-dependent effects of developmental and adult diet on life-history traits and their associations in outbred Drosophila melanogaster population
用于研究药物载体和细菌通过活体黏膜屏障传输的人体中流体肠道模型	Wang, C.-M.	PDF	N/A	Human Mesofluidic Intestinal Model for Studying Transport of Drug Carriers and Bacteria Through a Live Mucosal Barrier
可及的染色质区域和DNA甲基化调控基因表达，导致芸苔属异源三倍体杂种的农艺性状发生变化	Cheng, D.	PDF	N/A	Accessible chromatin regions and DNA methylation regulate gene expression leading to changes in agronomic traits in Brassica allotriploid hybrids
聚合溶酶体靶向嵌合体：无需共用溶酶体靶向受体的胞外靶向蛋白降解	Lu, R. H.-H.	PDF	N/A	Polymeric Lysosomal-Targeting Chimeras: Extracellular Targeted Protein Degradation Without Co-opting Lysosome-Targeting Receptors
在常染色体隐性多囊肾病中，升高Gli3的逆转并未改变囊肿的形成。	Russell, L. G.	PDF	N/A	Reversal of elevated Gli3 in Autosomal Recessive Polycystic Kidney Disease does not alter cystogenesis
与摄食、先天免疫和行为调节相关的扁形动物分泌细胞类型	Mayorova, T. D.	PDF	N/A	Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior
微妙平衡的导航：点突变作弊病毒破坏病毒复制周期	Meir, M.	PDF	N/A	Navigating a fine balance: point-mutant cheater viruses disrupt the viral replication cycle
Tbx4缺失影响出生后肺发育并易导致肺动脉高压。	Maldonado-Velez, G.	PDF	N/A	Loss of Tbx4 Affects Postnatal Lung Development and Predisposes to Pulmonary Hypertension.
MutLgamma 在拟南芥中强制执行减数分裂交叉。	Durand, S.	PDF	N/A	MutLgamma enforces meiotic crossovers in Arabidopsis thaliana
开发并广泛测序了一个广泛认可的“瓶中基因组”匹配的肿瘤-正常配对样本，用于体细胞基准测试。	McDaniel, J. H.	PDF	N/A	Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair for somatic benchmarks
叉头框F1在肺动脉高压病理生物学中的作用	Gomez-Arroyo, J.	PDF	N/A	Role of Forkhead box F1 in the Pathobiology of Pulmonary Arterial Hypertension
开发一种小分子表观遗传再生疗法。通过皮下注射含有高剂量塞布他汀和视黄酸的海藻酸盐制剂，可促进组织生长、血管化和神经支配，并诱导广泛的表观遗传重编程。	Slonimska, P.	PDF	N/A	Development of a small-molecule epigenetic regenerative therapy. Subcutaneous administration of alginate formulations with high loads of zebularine and retinoic acid promotes tissue growth, vascularization and innervation and induces extensive epigenetic repatterning
统一表型本体（uPheno）：一个跨物种整合表型学的框架	Matentzoglu, N.	PDF	N/A	The Unified Phenotype Ontology (uPheno): A framework for cross-species integrative phenomics
局部方法计算蛋白质构象中立体化学的影响	da Rocha, W.	PDF	N/A	Influence of stereochemistry in a local approach for calculating protein conformations
卤化胆固醇改变了三元脂质膜的相行为	Mehta, D.	PDF	N/A	Halogenated cholesterol alters the phase behavior of ternary lipid membranes
研究新型血液处理方法以增强非小细胞肺癌生物标志物的鉴定	Karsten, E.	PDF	N/A	Investigating the use of novel blood processing methods to boost the identification of biomarkers of non-small cell lung cancer
Gli2 过表达改变了去分化脂肪肉瘤细胞的分化状态，并在原位肿瘤中导致免疫抑制性髓系表型	Bennett, N. E.	PDF	N/A	Gli2 Overexpression Alters the Differentiation Status of Dedifferentiated Liposarcoma Cells and Results in an Immunosuppressive Myeloid Phenotype in Orthotopic Tumors
SMARCB1的丧失在上皮样肉瘤中引发可靶向的表观遗传脆弱性	Jin, J. X.	PDF	N/A	Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in Epithelioid Sarcoma
药理学SOS1抑制剂BI-3406在体内显示出与KRAS突变肿瘤中SOS1基因敲除相当的抗肿瘤活性。	BALTANAS, F. C.	PDF	N/A	Pharmacological SOS1 inhibitor BI-3406 demonstrates in vivo anti-tumor activity comparable to SOS1 genetic ablation in KRAS mutant tumors
独立推导预测药物诱发尖端扭转型室性心动过速的心律失常轴	Heitmann, S.	PDF	N/A	Independent derivations of the axis of arrhythmia for predicting drug-induced torsades de pointes
增加cGMP可改善微血管运动训练的适应性，与内皮一氧化氮合酶无关。	Winn, N. C.	PDF	N/A	Increased cGMP improves microvascular exercise training adaptations independent of endothelial nitric oxide synthase
急性簇细胞缺失导致小肠吸收不良及分泌细胞和免疫细胞谱系的改变	Momoh, M.	PDF	N/A	Acute tuft cell ablation induces malabsorption and alterations in secretory and immune cell lineages in small intestine
隔离生长激素对寿命和代谢的直接影响	Lasher, A. T.	PDF	N/A	Isolating the Direct Effects of Growth Hormone on Lifespan and Metabolism
数据独立采集质谱法作为元蛋白质组学的工具：使用模型微生物组进行实验室间比较	Rajczewski, A. T.	PDF	N/A	Data-Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome
SMoRe GloS：一种高效且灵活的框架，用于推断基于代理模型参数的全局敏感性	Bergman, D. R.	PDF	N/A	SMoRe GloS: An efficient and flexible framework for inferring global sensitivity of agent-based model parameters
基于机器学习的空间代谢谱预测揭示了形态学对星形胶质细胞能量代谢的影响	Papavasileiou, P.	PDF	N/A	Machine Learning-based Predictions of Spatial Metabolic Profiles Demonstrate the Impact of Morphology on Astrocytic Energy Metabolism
肽-MHC靶向的逆转录病毒能够实现肿瘤特异性T细胞的体内扩增及基因传递。	Xu, E. J.	PDF	N/A	Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells
BCR连接特异性地抑制IgE类别转换重组	Wade-Vallance, A. K.	PDF	N/A	BCR ligation selectively inhibits IgE class switch recombination
克服突变KRAS表位翻译后修饰引起的免疫逃逸，实现TCR工程化T细胞介导的抗肿瘤活性	Lee, J. W.	PDF	N/A	Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-engineered T cell-mediated antitumor activity
凝聚素介导的染色质重塑调控传统树突状细胞的分化和功能	Adams, N. M.	PDF	N/A	Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells
基于SATAY的化学基因组筛选揭示了抗真菌抗性机制及ATI-2307和壳聚糖敏感性的关键决定因素	Karadzas, M. T.	PDF	N/A	SATAY-Based Chemogenomic Screening uncovers Antifungal Resistance Mechanisms and Key Determinants of ATI-2307 and Chitosan Sensitivity
沙漠生态区中暗色岩燕的适应性筑巢策略：对保护和仿生创新的启示	Mukherjee, M.	PDF	N/A	Adaptive Nesting Strategies of Dusky Crag Martins in desert ecoregions: Implications for Conservation and Bioinspired Innovations
评估水电大坝梯度下的水禽生物多样性：了解库里楚大坝引起的河流碎片化对库里楚河流域的影响	Nidup, T.	PDF	N/A	Assessing Aquatic Avian Biodiversity along Hydropower Dam Gradient: Understanding Impacts of Kurichhu Dam-Induced River Fragmentation in Kurrichu River Basin
亚洲狼的复杂基因组祖先及其在南方的分布，以及驱动大陆层面遗传多样性的因素	Hennelly, L.	PDF	N/A	Complex genomic ancestry in southern regions and drivers of continental-level genetic diversity in the wolves of Asia
在杂交的Mimulus猴面花精细镶嵌体中，繁殖隔离的波动与稳定的祖先结构并存	Farnitano, M. C.	PDF	N/A	Fluctuating reproductive isolation and stable ancestry structure in a fine-scaled mosaic of hybridizing Mimulus monkeyflowers
现代铁氧化菌支系的近期起源及其铁代谢支系忠诚度较低	Tamre, E.	PDF	N/A	Recent origin of modern clades of iron oxidizers and low clade fidelity of iron metabolisms
gReLU：一种用于DNA序列建模和设计的综合框架	Lal, A.	PDF	N/A	gReLU: A comprehensive framework for DNA sequence modeling and design
苋菜（Amaranthus palmeri）、反枝苋（Amaranthus retroflexus）和杂交苋（Amaranthus hybridus）的染色体级别基因组组装使得进行基因组比较和鉴定性别决定区域成为可能。	Raiyemo, D. A.	PDF	N/A	Chromosome-level assemblies of Amaranthus palmeri, Amaranthus retroflexus, and Amaranthus hybridus allow for genomic comparisons and identification of a sex-determining region
MoEFold2D：结合深度学习和基于物理的专家混合，保障RNA二级结构预测	Qiu, X.	PDF	N/A	MoEFold2D: Safeguarding RNA Secondary Structure Prediction with a Mixture of Deep Learning and Physics-based Experts
对葡萄膜黑色素瘤中INPP5A的研究揭示了新的钙瞬变现象	Onken, M. D.	PDF	N/A	Examination of INPP5A in uveal melanoma uncovers novel calcium transients
突出力和细胞间粘附在肿瘤团簇集体迁移中起着关键作用。	Wang, H.	PDF	N/A	Protrusion force and cell-cell adhesion play a critical role in collective tumor cluster migration
癌症中整合素蛋白社交网络的全家福光近邻分析	Carlos, A. J.	PDF	N/A	Family-Wide Photoproximity Profiling of Integrin Protein Social Networks in Cancer
在缺乏调节性T细胞（Tregs）的情况下，IL15/IL15Rα复合物在放射治疗后能够诱导抗肿瘤免疫反应，但无法诱导祖细胞TCF1+ CD8 T细胞的扩增。	Piper, M.	PDF	N/A	IL15/IL15Rα complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to induce expansion of progenitor TCF1+ CD8 T cells
PARP7的丧失增加了I型干扰素信号传导，并通过增强免疫细胞浸润来阻止胰腺肿瘤生长。	Kannen, V.	PDF	N/A	Loss of PARP7 increases type I interferon signalling and prevents pancreatic tumour growth by enhancing immune cell infiltration
蓝贻贝（Mytilus edulis）中首次发现六鞭毛虫（Hexamita nelsoni）：形态学、系统发育及宿主-寄生虫相互作用	Alfjorden, A.	PDF	N/A	First report of Hexamita nelsoni in blue mussel (Mytilus edulis): morphology, phylogeny, and host-parasite interaction
不同的疟原虫蛋白激酶在雄性配子发生过程中驱动着微管组织中心、动粒和轴丝的组织结构。	Yanase, R.	PDF	N/A	Divergent Plasmodium protein kinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis
在成年心肌细胞的肌质网/内质网中蛋白质合成网络的发展	Sandmann, C.	PDF	N/A	Development of a protein synthesis network at the sarco/endoplasmic reticulum in adult cardiac myocytes
脑-体线粒体分布模式缺乏一致性，表明存在组织特异性和个体化的调控机制	Devine, J.	PDF	N/A	Brain-body mitochondrial distribution patterns lack coherence and point to tissue-specific and individualized regulatory mechanisms
在乳腺癌连续模型中，有丝分裂和中心体缺陷的特征	Elowe, S.	PDF	N/A	A characterization of mitotic and centrosomal defects in a continuum model of Breast Cancer
豚草（Ambrosia artemisiifolia）在不同入侵地快速并行适应的驱动力是大型效应结构变异	Battlay, P.	PDF	N/A	Rapid parallel adaptation in distinct invasions of Ambrosia artemisiifolia is driven by large-effect structural variants
欧洲森林和城市绿色空间中宿主-病原体群落组成的驱动因素	Sluydts, V.	PDF	N/A	Drivers of host-pathogen community assemblies in European forests and urban green spaces
温度依赖性捕食预示着更爬行动物化的未来	Grady, J. M.	PDF	N/A	Temperature-dependent predation predicts a more reptilian future
多代生物胁迫以ROS1依赖的方式增加了自发表观突变的发生率	Zhang, Z.	PDF	N/A	Multi-generational biotic stress increases the rate of spontaneous epimutations in a ROS1-dependent manner
稳定性裕度计算的协调与足长、足宽、步速和体质量影响的探究	Dussault-Picard, C.	PDF	N/A	Harmonization of Margin of Stability Calculations and Investigation of the Impact of Foot Length, Foot Width, Gait Speed, and Body Mass
IgGM：一种用于功能性抗体和纳米抗体设计的生成模型	Wang, R.	PDF	N/A	IgGM: A Generative Model for Functional Antibody and Nanobody Design
半管道（Halfpipe）：一种用于分析代谢标记RNA-seq数据以量化RNA半衰期的工具	Mueller, J. M.	PDF	N/A	Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives
利用生物系统中的代谢探针进行光热红外成像	Shuster, S. O.	PDF	N/A	Optical photothermal infrared imaging using metabolic probes in biological systems
肺腺癌中Y染色体的选择性丢失通过癌/睾丸抗原调节肿瘤免疫环境	Fischer, J.	PDF	N/A	Selective loss of Y chromosomes in lung adenocarcinoma modulates the tumor immune environment through cancer/testis antigens
造血干细胞来源的脂肪细胞消融可减轻同基因小鼠高级别浆液性癌模型中的肿瘤负担	Woodruff, E. R.	PDF	N/A	Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma
一种辅助性NLR能够靶向细胞器膜以触发免疫反应。	Ibrahim, T.	PDF	N/A	A helper NLR targets organellar membranes to trigger immunity
淋巴组织趋化因子检查点可防止CD8+ T细胞功能丧失	Altenburger, L. M.	PDF	N/A	A lymphoid tissue chemokine checkpoint prevents loss of CD8+ T cell functionality
适应性免疫通过在稳态期间抑制先天淋巴细胞中的持续性IFN-γ，塑造了先天性和上皮细胞的景观。	Mejri, O.	PDF	N/A	Adaptive immunity shapes innate and epithelial cell landscapes by silencing tonic IFN-gamma in innate lymphoid cells during homeostasis.
真菌感染的米氏琼楠花朵为三方育幼传粉系统中的甲虫传粉者提供了育幼场所。	Liu, M.-F.	PDF	N/A	Fungus-infected Meiogyne flowers offer a brood site for beetle pollinators in a tripartite nursery pollination system
采自甜椒的桃蚜对杀虫剂的抗性	Beekman, M. M.	PDF	N/A	Insecticide resistance in Myzus persicae collected from sweet pepper
一种新型荧光寿命层析成像技术	Nizam, N. I.	PDF	N/A	A Novel Technique for Fluorescence Lifetime Tomography
BioBrigit：一种结合深度学习和基于知识的混合方法，用于蛋白质中金属通路的建模：应用于双铜酪氨酸酶的应用	Marechal, J.-D.	PDF	N/A	BioBrigit, A Hybrid Deep Learning and Knowledge-based Approach to Model Metal Pathways in Proteins: Application to a Di-Copper Tyrosinase
HIV-1核输出复合体揭示了RNA在Crm1货物识别中的作用	Smith, A. M.	PDF	N/A	The HIV-1 Nuclear Export Complex Reveals the Role of RNA in Crm1 Cargo Recognition
视网膜母细胞瘤蛋白（Rb）口袋结构域中与癌症相关的错义变异的结构和功能分析	Castro, A.	PDF	N/A	Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain
定制基于CRISPR/Cas的表观基因组编辑器以实现可编程染色质乙酰化及降低细胞毒性	Goell, J. H.	PDF	N/A	Tailoring a CRISPR/Cas-based Epigenome Editor for Programmable Chromatin Acylation and Decreased Cytotoxicity
尿液微生物组与糖尿病及糖尿病肾病的关系：一项系统综述	Graells, T.	PDF	N/A	The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review
次黄嘌呤-5'-单磷酸脱氢酶（IMPDH/GuaB）抑制剂对伯氏疏螺旋体在标准及改良培养条件下生长的影响	Siegel, E. L.	PDF	N/A	Effects of Inosine-5'-Monophosphate Dehydrogenase (IMPDH/GuaB) Inhibitors on Borrelia burgdorferi Growth in Standard and Modified Culture Conditions
常见调控突变提高了铜绿假单胞菌在抗生素暴露下的单细胞存活率。	Ritz, D.	PDF	N/A	Common regulatory mutation increases single-cell survival to antibiotic exposures in Pseudomonas aeruginosa.
关闭差距：测试碳青霉烯和头孢菌素在治疗晚期炭疽中的疗效	Sittner, A.	PDF	N/A	Closing the gaps: testing the efficacy of carbapenem and cephalosporins in treating late-stage anthrax
评估氧扰动和过度曝气对活性污泥系统中可溶性微生物产物（SMP）生成和释放的影响	Zhou, X.	PDF	N/A	Assessing Oxygen Perturbation and Over-Aeration Impacts on Soluble Microbial Products (SMP) Production and Release in Activated Sludge Systems
禽类和牛场作为产ESBL大肠杆菌储库的一体化健康评估	Malik, H.	PDF	N/A	One Health assessment of poultry and cattle farms as reservoirs for ESBL-producing Escherichia coli
探究氧气扰动下潜在的微生物对代谢物产量增强的贡献：一种整合的宏基因组学和代谢组学方法	Zhou, X.	PDF	N/A	Investigating Potential Microbial Contributors to Enhanced Metabolite Production under Oxygen Perturbations: An Integrated Metagenomic and Metabolomic Approach
截留末端未脱磷酸的十一碳酰磷酸连接的寡糖中间体	Hong, Y.	PDF	N/A	Sequestration of dead-end undecaprenyl phosphate-linked oligosaccharide intermediate
通过引导微生物代谢生产高附加值生物化学品，实现废水资源回收	Zhou, X.	PDF	N/A	Resource Recovery from Wastewater By Directing Microbial Metabolism Toward Production of Value-added Biochemicals
早期生命牛奶饮食塑造婴儿肠道微生物群：关于微生物对母乳和配方奶的适应性证据。	Lawson, M. A. E.	PDF	N/A	Early life milk diets shape infant gut microbiota: evidence of microbial plasticity in response to breast and formula milk.
水杨酸衍生物的抗结核潜力及其pH驱动的抗菌机制	Laudouze, J.	PDF	N/A	Anti-tubercular potential and pH-driven mode of action of salicylic acid derivatives
燕麦（Avena sativa L.）对干旱胁迫的蛋白质组响应	Chen, C.	PDF	N/A	Proteomic responses of oat (Avena sativa L.) to drought stress
TDRD3作为一种选择性自噬受体，在自噬过程中具有双重功能，既参与自噬作用，又调节应激颗粒的稳定性。	Lloyd, R. E.	PDF	N/A	TDRD3 functions as a selective autophagy receptor with dual roles in autophagy and modulation of stress granule stability
寄生传播时间选择塑造了宿主冈比亚按蚊的转录反应，并提示免疫逃避	Silva, L. M.	PDF	N/A	Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion
评估辐射敏感性指数及12种趋化因子基因表达特征在CLIA实验室中的临床应用	Berglund, A.	PDF	N/A	Evaluating the Radiation Sensitivity Index and 12-chemokine gene expression signature for clinical use in a CLIA laboratory
scooby: 在单细胞分辨率下从DNA序列建模多模态基因组特征	Gagneur, J.	PDF	N/A	scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution
嵌合去泛素化酶工程揭示了USP30特异性抑制的结构基础及DUB配体结合的框架	Kazi, N. H.	PDF	N/A	Chimeric deubiquitinase engineering reveals structural basis for specific inhibition of USP30 and a framework for DUB ligandability
鉴定孤儿GPR25为趋化因子CXCL17的受体	Hu, W.-F.	PDF	N/A	Identification of the orphan GPR25 as a receptor of the chemokine CXCL17
通过贝叶斯模型选择整合蛋白质-多肽复合物的建模，使用AlphaFold和NMR化学位移扰动数据	Benavides, T. L.	PDF	N/A	Integrative Modeling of Protein-Polypeptide Complexes by Bayesian Model Selection using AlphaFold and NMR Chemical Shift Perturbation Data
气道应用的IVT mRNA疫苗需要特定的序列设计和高标准的纯化，以去除具有破坏性的双链RNA污染物。	Zhang, J.	PDF	N/A	Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminant
利用光遗传学技术快速可逆地调控出芽酵母细胞周期进程	Koutsoumpa, A.	PDF	N/A	Rapid and reversible regulation of cell cycle progression in budding yeast using optogenetics
病毒RNA kaposin促进的核体重组促进了卡波西肉瘤相关疱疹病毒基因表达	Kleer, M.	PDF	N/A	Nuclear body reorganization by the viral RNA kaposin promotes Kaposi's sarcoma-associated herpesvirus gene expression
评估非洲豆蔻（Aframomum melegueta）和几内亚胡椒（Piper guineense）提取物对黄瓜果实腐烂病原菌的抗菌活性	Akpan, P. S.	PDF	N/A	Assessing the antimicrobial activity of Aframomum melegueta and Piper guineense extract on pathogens of rot diseases of cucumber fruit
BRCA2 C端夹结构重构RAD51二聚体以结合B型DNA，从而维持复制叉的稳定性	Longo, M. A.	PDF	N/A	BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability
一个新颖的OsIAA3-OsARF16-OsBUL1模块调控水稻的粒型	Xian, F.	PDF	N/A	A novel OsIAA3-OsARF16-OsBUL1 module regulates grain size in rice
基因组大小与非转录区域大小之间的线性相关性	Chen, Z.-R.	PDF	N/A	The linear correlation between genome size and the size of the non-transcribing region
BTFBS：基于深度学习的细菌转录因子与结合位点预测	Jin, B.	PDF	N/A	BTFBS: binding-prediction of bacterial transcription factors and binding sites based on deep learning
# BioRxiv 2024-09-21 Papers

标题	作者	PDF链接	代码仓库	Title
无监督机器学习揭示了HeLa细胞在细胞周期阻滞解除后基因表达的时间成分	Maimon, T.	PDF	N/A	Unsupervised machine learning reveals temporal components of gene expression in HeLa cells following release from cell cycle arrest
SARS-CoV-2和HSV-1诱导人脑脊液中淀粉样蛋白聚集，导致可溶性蛋白质急剧减少。	Christ, W.	PDF	N/A	SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
冷适应性鲑科鱼类在世代内和跨世代环境变暖中的转录组响应	Penney, C. M.	PDF	N/A	Transcriptomic responses to within- and transgenerational environmental warming in a cold-adapted salmonid
通过交叉拟合加速基于R2的高维中介效应区间估计	Xu, Z.	PDF	N/A	Speeding up interval estimation for R2-based mediation effect of high-dimensional mediators via cross-fitting
活体中皮层下磁性物质的非指数横向弛豫衰减特性	Oliveira, R.	PDF	N/A	In-vivo characterization of magnetic inclusions in the subcortex from non-exponential transverse relaxation decay
肌动蛋白介导的细胞核形变调控多纤毛室管膜细胞的分化。	Basso, M.	PDF	N/A	Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation.
mbctools：一个用户友好的宏条形码分析和跨平台管道，用于分析多种生物的大量多样性扩增子测序数据。	Barnabe, C.	PDF	N/A	mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms
超低场儿科MRI在低收入和中等收入国家：使用多方向U-Net的超分辨率技术	Baljer, L.	PDF	N/A	Ultra-low-field paediatric MRI in low- and middle-income countries: super-resolution using a multi-orientation U-Net
丁香酚通过NRF2介导的氧化应激途径对1型糖尿病的保护作用	Jiang, Y.	PDF	N/A	The protective roles of Eugenol on type 1 diabetes mellitus through NRF2 mediated oxidative stress pathway
基于免疫受体分析和多克隆应答细胞的单细胞RNA表达的TCR转基因克隆筛选	Debeuf, N.	PDF	N/A	TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders
星形胶质细胞在海马体-内嗅皮层突触中介导两种形式的峰时依赖性抑制。	Martinez-Gallego, I.	PDF	N/A	Astrocytes mediate two forms of spike timing-dependent depression at entorhinal cortex-hippocampal synapses
胎盘纳米颗粒介导的IGF1基因治疗在豚鼠模型中纠正了胎儿生长受限	Davenport, B.	PDF	N/A	Placental Nanoparticle-mediated IGF1 Gene Therapy Corrects Fetal Growth Restriction in a Guinea Pig Model
目标学习而非反向传播解释了哺乳动物新皮层中的学习过程	Aceituno, P. V.	PDF	N/A	Target Learning rather than Backpropagation Explains Learning in the Mammalian Neocortex
氨基酸与葡萄糖发酵维持小鼠及人类恶性胶质瘤细胞的ATP含量	Lee, D. C.	PDF	N/A	Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells
用于研究疟原虫主要毒力因子功能的一个系统	Cronshagen, J.	PDF	N/A	A system for functional studies of the major virulence factor of malaria parasites
线粒体输入蛋白TIMM50缺乏的生化和神经生理学效应	Paz, E.	PDF	N/A	Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50
珊瑚宿主积极积累无机碳以维持与共生藻的共生关系	Zhang, B.	PDF	N/A	Coral hosts actively accumulate inorganic carbon for Symbiodiniaceae to maintain symbiotic relationships
丘脑皮层对分层认知控制的贡献	Chen, X.	PDF	N/A	Thalamocortical contributions to hierarchical cognitive control
β-1,6-葡聚糖在双层真菌细胞壁的结构和重塑中起着核心作用。	Bekirian, C.	PDF	N/A	Beta-1,6-glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall
植物系统中的Mobius组装强调了基因调控中的启动子-编码序列-终止子相互作用	Kocaoglan, E. G.	PDF	N/A	Mobius Assembly for Plant Systems highlights promoter-coding sequence terminator interaction in gene regulation
参考基因组的纬度梯度	Linck, E. B.	PDF	N/A	A latitudinal gradient of reference genomes
通过折叠和稳定性的全面指南，揭示细胞色素c与疾病的关联	Yousaf, M. A.	PDF	N/A	A comprehensive guide through the fold and stability of cytochrome c with implications for disease
下颌关节假体在完整咀嚼周期中的生物力学评估	Ghosh, R.	PDF	N/A	Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle
单倍型解析组装提供了对新疆最古老葡萄品种（木纳格）基因组组成的深入了解。	Zhong, H.	PDF	N/A	Haplotype-resolved assemblies provide insights into genomic makeup of the oldest grapevine cultivar (Munage) in Xinjiang
基于深度学习的基因扰动效应预测尚未超越简单的线性方法。	Ahlmann-Eltze, C.	PDF	N/A	Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods
将全长FLT1表达重定向至其可溶性异构体可促进缺血后血管生成。	Bundalo, M.	PDF	N/A	Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis
定性脑电图异常表明大脑网络向抑制主导型转变。来自EU-AIMS LEAP研究的结果显示	Juarez-Martinez, E. L.	PDF	N/A	Qualitative EEG abnormalities signal a shift towards inhibition-dominated brain networks. Results from the EU-AIMS LEAP studies
通过个性化抗原无关筛选方法识别的T细胞受体靶向共享的新抗原KRAS Q61H	Lennerz, V.	PDF	N/A	T-cell receptors identified by a personalized antigen-agnostic screening approach target shared neoantigen KRAS Q61H
TBC1D24调控线粒体与内质网-线粒体接触位点	Benhammouda, S.	PDF	N/A	TBC1D24 regulates mitochondria and endoplasmic reticulum-mitochondria contact sites
在妊娠中期，母体血浆中apelin水平较低与重度、早发型胎儿生长受限的不良妊娠结局相关。	Braun, N.	PDF	N/A	Low maternal plasma apelin in the second trimester is associated with adverse pregnancy outcome in severe, early-onset fetal growth restriction
通过ERECTA的触发开关机制预防配体感知前后的不当信号传递	Chen, L.	PDF	N/A	Preventing Inappropriate Signals Pre- and Post-Ligand Perception by a Toggle-Switch Mechanism of ERECTA
主要镰刀菌物种在温度和水活性约束组合下的生理生态行为	Foulongne-Oriol, M.	PDF	N/A	Ecophysiological Behaviour Of Major Fusarium Species In Response To Combinations Of Temperature And Water Activity Constraints
Sox9可防止视网膜退化，并在成年小鼠眼中对角膜缘干细胞的分化起着必要作用。	Hurtado, A.	PDF	N/A	Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye
亲缘关系密切的叶蝉亚科中微生物群落的显著差异：Typhlocybinae和Eurymelinae（叶蝉科，半翅目）	Kobiałka, M.	PDF	N/A	Extremely distinct microbial communities in closely related leafhopper subfamilies: Typhlocybinae and Eurymelinae (Cicadellidae, Hemiptera)
HuR对稳态B细胞信号转录后调控对于先天性B细胞的维持和功能是必需的。	Capitan-Sobrino, D.	PDF	N/A	Post-transcriptional control of homeostatic B- cell signalling by HuR is required for innate B cell maintenance and function.
TIRTL-seq：深度、定量且经济实惠的配对TCR受体组测序	Pogorelyy, M. V.	PDF	N/A	TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing
物种间生长特征的差异正在推动谷物-豆类间作产量：基于聚合数据集的统计学习方法	Mahmoud, R.	PDF	N/A	Differences in growth features between species are driving cereal-legume intercrop yield: a statistical learning approach based on aggregated dataset
BirdNET在欧洲城市声学鸟类监测方面与专家一样出色。	Fairbairn, A. J.	PDF	N/A	BirdNET is as good as experts for acoustic bird monitoring in a European city
蒸气压亏缺主导了生态系统光合量子产量的时空变化。	Yu, L.	PDF	N/A	Vapor pressure deficit dominates the spatiotemporal variations in ecosystem photosynthetic quantum yield
伊利诺伊州西尼罗病毒传播媒介（库蚊和淡色库蚊）中广泛存在的杀虫剂抗性机制证据	Noel, K.	PDF	N/A	Mechanistic evidence of widespread insecticide resistance among Illinois West Nile virus vectors (Culex pipiens and Culex restuans)
灵长类动物（包括人类）大脑进化与手部灵巧性的协同演化	Baker, J.	PDF	N/A	The coevolution of encephalization and manual dexterity in hominins and other primates
纤毛虫细胞衰老的起源	Mitteldorf, J.	PDF	N/A	Origin of Cellular Senescence in Ciliates
基因组和表型预测在苹果育种中应用的评估	Jung, M.	PDF	N/A	Evaluation of genomic and phenomic prediction for application in apple breeding
通过解决合成环状RNA中的污染物来缓解细胞功能障碍	Zhang, Z.	PDF	N/A	Mitigating Cellular Dysfunction by Addressing Contaminants in Synthetic circRNA
胶质母细胞瘤对溶瘤HSV1反应的纵向分析指导PLX3397联合用药以增强病毒易感性	Ito, H.	PDF	N/A	Longitudinal analysis of glioblastoma response to oncolytic HSV1 guides PLX3397 combination for enhanced viral permissiveness
MAASWERP研究：一项关于测量老年小鼠主动脉生物力学的国际比较案例研究	Neutel, C. H. G.	PDF	N/A	The MAASWERP study: An international, comparative case study on measuring biomechanics of the aged murine aorta
跨表达分析揭示了空间转录组学中协调基因表达的模式	Sarwar, A.	PDF	N/A	Cross-expression analysis reveals patterns of coordinated gene expression in spatial transcriptomics
通过使用扭曲分子的属性条件训练来提高3D分子生成的结构合理性	Vost, L.	PDF	N/A	Improving Structural Plausibility in 3D Molecule Generation via Property-Conditioned Training with Distorted Molecules
利用MELISSA模型进行安全评估的整合位点数据建模	Lin, T.-Y.	PDF	N/A	Modeling integration site data for safety assessment with MELISSA
BrainSTEM：一种多分辨率胎儿脑图谱，用于评估人中脑培养的保真度	Toh, H.	PDF	N/A	BrainSTEM: A multi-resolution fetal brain atlas to assess the fidelity of human midbrain cultures
校准额外的计算工具扩展了ClinGen在PP3/BP4标准下对变异分类的推荐选项	Bergquist, T.	PDF	N/A	Calibration of additional computational tools expands ClinGen recommendation options for variant classification with PP3/BP4 criteria
整合多种实验信息以辅助GRASP进行蛋白质复合物结构预测	Xie, Y.	PDF	N/A	Integrating various Experimental Information to Assist Protein Complex Structure Prediction by GRASP
从多种RNA-DNA连接数据中检测统计学上稳健的相互作用	Zehr, S.	PDF	N/A	Detection of statistically robust interactions from diverse RNA-DNA ligation data
Bolero：一种专门的工作流程，用于从结合5RACE扩增转录本的长读长测序方法中解析乙型肝炎病毒转录组	Grand, X.	PDF	N/A	Bolero: a dedicated workflow to decipher Hepatitis B virus transcriptome from long-reads sequencing method coupled to 5RACE amplification of transcripts
从DNA序列预测和功能解析染色体间基因组架构的TwinC方法	Jha, A.	PDF	N/A	Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC
肌纤维特异性FoxP1敲除可保护雄性小鼠免受胰腺癌引起的肌肉萎缩，但对雌性小鼠无效。	Schonk, M. M.	PDF	N/A	Myofiber-specific FoxP1 knockout protects against pancreatic cancer-induced muscle wasting in male but not female mice.
成纤维细胞调节人乳头瘤病毒阳性角质形成细胞的转化潜能	James, C. D.	PDF	N/A	Fibroblasts Regulate the Transformation Potential of Human Papillomavirus-positive Keratinocytes
视网膜神经节细胞对阿尔茨海默病中致病性tau的易感性	Davis, M. R.	PDF	N/A	Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease
一种动力学筛选方法加速了靶向蛋白质降解剂的开发	Fan, A. T.	PDF	N/A	A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development
选择性Rho激酶2抑制剂KD025在精神分裂症的遗传和药理学小鼠模型中表现出类似抗精神病药物的效果。	Tanaka, R.	PDF	N/A	Antipsychotic-like effects of the selective Rho-kinase 2 inhibitor KD025 in genetic and pharmacological mouse models of schizophrenia
不活动介导的分子适应：从一种新的临床前体力活动减少模型中获得的见解	Meyer, A.	PDF	N/A	Inactivity-mediated molecular adaptations: insights from a novel pre-clinical model of physical activity reduction
体外补充DHA可抑制人原代巨噬细胞中前列腺素E2的形成	Kirchhoff, R.	PDF	N/A	Ex vivo DHA supplementation suppresses prostaglandin E2 formation in primary human macrophages
银屑病血液和皮肤中免疫细胞的单细胞图谱	Deng, J.	PDF	N/A	Single-cell Landscape of Immune Cells in Blood and Skin in Psoriasis
听音乐在双眼竞争期间调节对绘画的视觉感知	Jiang, X.	PDF	N/A	Listening to music modulates visual perception of paintings during binocular rivalry
跨功能模块的生物衰老高维表征	Ying, K.	PDF	N/A	High-dimensional Ageome Representations of Biological Aging across Functional Modules
定量蛋白质组学揭示了M1和M2单核细胞来源的人类巨噬细胞外泌体货物的差异	Pantazi, P.	PDF	N/A	Quantitative proteomics reveals differential extracellular vesicle cargo from M1 and M2 monocyte-derived human macrophages
谷氨酰胺的可用性调节组织中树突状细胞亚群	Lobel, G. P.	PDF	N/A	Glutamine availability regulates cDC subsets in tissue
CCR2限制了CD8 TRM细胞的炎症功能，这些功能在从WNV脑炎恢复期间损害了识别记忆	Ai, S.	PDF	N/A	CCR2 limits inflammatory functions of CD8 TRM cells that impair recognition memory during recovery from WNV encephalitis
通过性状-环境关系揭示的环境适应微生物策略	Ren, M.	PDF	N/A	Microbial strategies of environmental adaptation revealed by trait-environmental relationships
基于生理学的人口模型/非洲十三个入侵物种的GIS分析：为何生物学至关重要	Gutierrez, A. P.	PDF	N/A	Physiologically based demographic model/GIS analyses of thirteen invasive species in Africa: why the biology matters
纠缠进化模型：应用于自适应突变	Ross, P.	PDF	N/A	Entangled Evolution Model: Application to Adaptive Mutation
水蓼（Amaranthus tuberculatus）中性的进化、多样性和遗传结构	Kreiner, J. M.	PDF	N/A	The evolution, diversity, and genetic architecture of sex in waterhemp (Amaranthus tuberculatus)
个体间不同的重组景观是由多态的可移动元件驱动的。	Huang, Y.	PDF	N/A	Varying recombination landscapes between individuals are driven by polymorphic transposable elements
小鼠造血系统的克隆动态与体细胞演化	Kapadia, C. D.	PDF	N/A	Clonal dynamics and somatic evolution of haematopoiesis in mouse
禾谷镰刀菌假基因的鉴定与结构表征。	Rau, D.	PDF	N/A	Identification and structural characterization of pseudogenes in Fusarium graminearum.
利用多层单细胞组学技术表征人巨细胞病毒特异性CD8+ T细胞	Gemuend, I.	PDF	N/A	Characterizing human CMV-specific CD8+ T cells using multi-layer single-cell omics
具有触发阀的开敞式水渠系统中毛细流动的动力学特性	Tokihiro, J. C.	PDF	N/A	The dynamics of capillary flow in an open-channel system featuring trigger valves
一个新的用于估计同义替换选择作用的比较框架。	Verdonk, H.	PDF	N/A	A new comparative framework for estimating selection on synonymous substitutions.
超越关联性：疾病致病基因因果关系抽取基准数据集（CRED）、其比较评估、解读与应用	Bansal, N.	PDF	N/A	Beyond associations: A benchmark Causal Relation Extraction Dataset (CRED) of disease-causing genes, its comparative evaluation, interpretation and application
早期肺癌肿瘤微环境中存在的Tenascin-C通过整合素激活和FAK促进肿瘤进展。	Mendoza, M. C.	PDF	N/A	Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin activation and FAK
大麻二酚（CBD）对人胶质母细胞瘤细胞核心区和浸润边界区的差异性抗增殖作用	Abassi-Rana, G.	PDF	N/A	DIFFERENTIAL ANTIPROLIFERATIVE EFFECTS OF CANNABIDIOL (CBD) IN THE CORE AND INFILTRATIVE BOUNDARY OF HUMAN GLIOBLASTOMA CELLS
CDK4失活平衡了三阴性乳腺癌细胞对凋亡的抵抗与代谢敏感性的增强	Ziegler, D. V.	PDF	N/A	CDK4 inactivation balances resistance to apoptosis with heightened metabolic sensitivity in triple negative breast cancer cells
截短的补体因子H Y402基因疗法治愈C3肾小球肾炎	Chew, L. A.	PDF	N/A	Truncated Complement Factor H Y402 Gene Therapy Cures C3 Glomerulonephritis
室温气溶胶脱水绿色荧光蛋白	Pan, Z.	PDF	N/A	Room Temperature Aerosol Dehydration of Green Fluorescence Protein
代谢组学和转录组学分析的整合揭示了ChREBP转录因子在能量代谢中的新调控功能	An, J.	PDF	N/A	Integration of metabolomic and transcriptomic analyses reveals novel regulatory functions of the ChREBP transcription factor in energy metabolism
GCK-MODY中独特的持续时间与饮食依赖性脂质谱及肾脏并发症	Huang, Y.	PDF	N/A	Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
牛淋巴和非淋巴组织中的树突状细胞亚群：正在进行的工作	Talker, S. C.	PDF	N/A	Bovine dendritic-cell subsets in lymphoid and non-lymphoid tissues: work in progress
一种人类同源的SIR2抗病毒蛋白通过TLR途径介导免疫	Bonhomme, D.	PDF	N/A	A human homolog of SIR2 antiphage proteins mediates immunity via the TLR pathway
一种用于重建性社会学习演化的神经网络模型	Chisausky, J.	PDF	N/A	A neural network model for the evolution of reconstructive social learning
优化冷冻保存遗传资源在动物种群选择和保护中的应用	Jacques, A.	PDF	N/A	Optimizing the use of cryopreserved genetic resources for the selection and conservation of animal populations
使用自回归生成模型重建祖先蛋白质序列	De Leonardis, M.	PDF	N/A	Reconstruction of ancestral protein sequences using autoregressive generative models
推进对抗胶质母细胞瘤的临床反应：评估SHP1705 CRY2激活剂在临床前模型中的疗效及在I期试验中的安全性	Chan, P.	PDF	N/A	Advancing Clinical Response Against Glioblastoma: Evaluating SHP1705 CRY2 Activator Efficacy in Preclinical Models and Safety in Phase I Trials
苯甲酸钠通过SKN-1/Nrf2信号通路促进脂肪积累和衰老：来自秀丽隐杆线虫模型的证据	Lee, J. D.	PDF	N/A	Sodium Benzoate Promotes Fat Accumulation and Aging via the SKN-1/Nrf2 Signaling Pathway: Evidence from the Caenorhabditis elegans Model
比较多系统萎缩与帕金森病中的α-突触核蛋白相互作用组，揭示了独特的和共有的病理特征。	Killinger, B. A.	PDF	N/A	Comparing alpha-synuclein-interactomes between multiple systems atrophy and Parkinsons disease reveals unique and shared pathological features.
用于从多通道音频中定位啮齿动物发声的Vocal Call Locator基准（VCL）	Peterson, R. E.	PDF	N/A	Vocal Call Locator Benchmark (VCL) for localizing rodent vocalizations from multi-channel audio
来自精神分裂症个体的hiPSC衍生星形胶质细胞促进类似小胶质细胞的吞噬作用和趋化性改变	Cardozo, P. L.	PDF	N/A	hiPSC-derived astrocytes from individuals with schizophrenia promote alterations in phagocytosis and chemotaxis of microglial-like cells
下肢指向评估不完全脊髓损伤后节段间动力学及其与本体感觉障碍的关联作用。	Malik, R. N.	PDF	N/A	Lower limb pointing to assess intersegmental dynamics after incomplete spinal cord injury and the associated role of proprioceptive impairments.
在青蛙变态发育过程中，脊髓神经元的多样性随着从游泳到四肢运动的转变呈指数级增长。	Vijatovic, D.	PDF	N/A	Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis
在情绪面孔匹配任务中并发的大规模脑动态及其与行为和心理健康的关系	Korponay, C.	PDF	N/A	Concurrent large-scale brain dynamics during the emotional face matching task and their relation to behavior and mental health
人类内侧丘脑枕核参与面部和触觉处理，并根据当前的刺激动态调整其皮质连接性。	Gaudet, M.	PDF	N/A	Human medial pulvinar is involved in face and tactile processing and dynamically adjusts its cortical connectivity based on ongoing stimulation
在声学听力听者和耳蜗植入使用者中，高呈现声级下听觉努力增加和言语辨别能力下降	Huang, C. G.	PDF	N/A	Increased listening effort and decreased speech discrimination at high presentation sound levels in acoustic hearing listeners and cochlear implant users
脂联素在母体肥胖暴露的成年后代中，恢复了阻力血管的胆碱能舒张作用。	Murphy, M.	PDF	N/A	Adiponectin restores cholinergic vasodilation in resistance vessels from adult offspring exposed to maternal obesity in utero
终身健身优势：繁殖地忠诚度和近亲繁殖成本低，使得一种鸟类合作繁殖者能够容忍近亲繁殖。	Shah, S.	PDF	N/A	Lifetime fitness benefits of breeding site fidelity and low costs of inbreeding permit inbreeding tolerance in an avian cooperative breeder
纹状体和海马中奖励的情感和信息成分的差异表征	Shen, X.	PDF	N/A	Differential representations for affective and informative components of reward in the striatum and hippocampus
前扣带回前额叶皮层中的组蛋白去乙酰化酶5限制与情境相关的可卡因寻求行为	Barry, S. M.	PDF	N/A	Histone deacetylase 5 in prelimbic prefrontal cortex limits context-associated cocaine seeking
乙酰胆碱在不确定性下的强化学习和决策中的作用	Kurtenbach, H.	PDF	N/A	A role for acetylcholine in reinforcement learning and decision making under uncertainty
一项大规模队列研究（n = 591）探讨了丘脑间粘连的存在与否对认知、神经影像学和遗传结果的影响。	Vidal, J. P.	PDF	N/A	A large cohort study (n = 591) on the impact of the presence or absence of the interthalamic adhesion: cognitive, neuroimaging, and genetic results
可卡因自我戒断促进了小胶质细胞对星形胶质细胞的修剪，从而推动了可卡因的觅药行为。	Testen, A.	PDF	N/A	Abstinence from cocaine self-administration promotes microglia pruning of astrocytes which drives cocaine-seeking behavior
刺激椭圆囊不规则纤维会在前庭核复合体（VNC）中产生从前到后的活动梯度，但不会在前庭小脑（VeCb）中产生。	Holt, A. G.	PDF	N/A	Stimulation of otolith irregular fibers produces a rostro-caudal gradient in activity in the vestibular nuclear complex (VNC), but not the vestibulocerebellum (VeCb)
SETα和SETβ在早期细胞命运决定中具有不同的作用	Lim, P. S. L.	PDF	N/A	Distinct Roles for SETα and SETβ in Early Cell Fate Decisions
传粉者Eristalis tenax中固有花卉偏好的消失	Mishra, A.	PDF	N/A	Extinction of innate floral preferences in the pollinator Eristalis tenax
椎间盘髓核细胞网络建模	Tseranidou, S.	PDF	N/A	Nucleus Pulposus Cell Network Modelling in the Intervertebral Disc
统一大模型：一种全新整体建模范式，用于在完整和谐的尺度上研究生物系统	Aucello, R.	PDF	N/A	UnifiedGreatMod: A New Holistic Modeling Paradigm for Studying Biological Systems on a Complete and Harmonious Scale
单细胞网络方法解析妇科及乳腺癌中的代谢调控	Srivastava, A.	PDF	N/A	A Single-Cell Network Approach to Decode Metabolic Regulation in Gynecologic and Breast Cancers
小胶质细胞决定免疫挑战环境，并促进布洛芬在人视网膜类器官中的作用。	Schmied, V.	PDF	N/A	Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids.
疱疹病毒膜融合激活的变构机制	Gonzalez-Del Pino, G. L.	PDF	N/A	Allosteric mechanism of membrane fusion activation in a herpesvirus
通过Sideroxydans lithotrophicus ES-1中的MtoAB孔蛋白-多血红素细胞色素复合物进行的微生物磁铁矿氧化	Keffer, J. L.	PDF	N/A	Microbial magnetite oxidation via MtoAB porin-multiheme cytochrome complex in Sideroxydans lithotrophicus ES-1
大肠杆菌中rRNA操纵子的聚集被σH破坏。	Ho, K.	PDF	N/A	Clustering of rRNA operons in E. coli is disrupted by σH
生牛奶中甲型H5N1流感病毒的热灭活谱	Nooruzzaman, M.	PDF	N/A	Thermal inactivation spectrum of influenza A H5N1 virus in raw milk
巨型转座子推动了热厌氧杆菌（Thermoanaerobacter kivui）对一氧化碳的适应	Hocq, R.	PDF	N/A	A megatransposon drives the adaptation of Thermoanaerobacter kivui to carbon monoxide
在受限条件下细菌的生长需要转录适应以抵抗代谢物引起的膨压增加	Le Blanc, L.	PDF	N/A	Bacterial growth under confinement requires transcriptional adaptation to resist metabolite-induced turgor pressure build-up
一种隐秘的噬菌体转录因子通过宿主基因调控驱动表型变化	Lally, P.	PDF	N/A	A Cryptic Prophage Transcription Factor Drives Phenotypic Changes via Host Gene Regulation
饮食诱导的Rad51c突变小鼠线粒体DNA复制不稳定性驱动炎症性贫血的性别偏向	Tomaszowski, K.-H.	PDF	N/A	Diet induced mitochondrial DNA replication instability in Rad51c mutant mice drives sex-bias in anemia of inflammation
神经化样蛋白差异性激活Notch配体	Airich, A.	PDF	N/A	Neuralized-like proteins differentially activate Notch ligands
一个依赖于气候和人口的扩散模型预测了白纹伊蚊在欧洲的传播情况。	Barman, S.	PDF	N/A	A climate and population dependent diffusion model forecasts the spread of Aedes Albopictus mosquitoes in Europe
使用SomaScan和Olink检测方法进行蛋白质丰度定量时，体外溶血和反复冻融循环的影响	Candia, J.	PDF	N/A	Effects of in vitro hemolysis and repeated freeze-thaw cycles in protein abundance quantification using the SomaScan and Olink assays
藻胆蛋白使海洋硅藻表现出社会行为	Font-Munoz, J. S.	PDF	N/A	Phytochromes Enable Social Behavior in Marine Diatoms
保守非编码元件的剧烈进化变化伴随着Caenorhabditis inopinata的非凡特征	Tamagawa, K.	PDF	N/A	Dramatic evolutionary changes of conserved noncoding elements accompanied by extraordinary features of Caenorhabditis inopinata
揭示氨基糖苷类药物与假尿苷在IRES翻译中的分子相互作用	Zhao, Y.	PDF	N/A	Unveil the Molecular Interplay between Aminoglycosides and Pseudouridine in IRES Translation
ERAP1活性不仅调节免疫肽组，还影响癌细胞的蛋白质组、代谢和应激反应。	Nikopaschou, M.	PDF	N/A	ERAP1 activity modulates the immunopeptidome but also affects the proteome, metabolism and stress responses in cancer cells
特定C2H2锌指结构域中的构象动力学使锌响应基因抑制在S. pombe中得以实现	Wadhwa, V.	PDF	N/A	Conformational dynamics in specialized C2H2 zinc finger domains enable zinc-responsive gene repression in S. pombe
Rubisco包装及天然β-羧酶体的化学计量组成	Sun, Y.	PDF	N/A	Rubisco packaging and stoichiometric composition of a native β-carboxysome
从头设计的别构可调蛋白纤维的成核限制组装和极性生长	Shen, H.	PDF	N/A	Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament
AlphaFold2和AlphaFold3在人类与寄生虫相互作用预测中导致显著不同的结果	Ozden, B.	PDF	N/A	AlphaFold2 and AlphaFold3 leads to significantly different results in human-parasite interaction prediction
基因组中的基序分布提供了关于基因簇集和协同调控的见解。	Chakraborty, A.	PDF	N/A	Motif distribution in genomes gives insights into gene clustering and co-regulation
BioPAX-Explorer：一个面向对象的Python框架，用于克服查询生物网络的复杂性	Moreews, F.	PDF	N/A	BioPAX-Explorer: a Python Object-Oriented framework for overcoming the complexity of querying biological networks
一种环状多肽通过结合异常暴露的SNAP25靶向胶质母细胞瘤	Arias, A. G.	PDF	N/A	A CYCLIC PEPTIDE TARGETS GLIOBLASTOMA BY BINDING TO ABERRANTLY EXPOSED SNAP25
利什曼原虫墨西哥亚种中N-乙酰转移酶10（NAT10）的功能表征	Rodrigues Maran, S.	PDF	N/A	Functional characterization of N-acetyltransferase 10 (NAT10) in Leishmania mexicana
水生哺乳动物中普遍存在的选择放松	Farina, B. M.	PDF	N/A	Widespread selection relaxation in aquatic mammals
胚胎干细胞中TF-DNA识别的双峰特异性	Povolotskii, M.	PDF	N/A	Bimodal Specificity of TF-DNA Recognition in Embryonic Stem Cells
通过嵌合eCLIP方法在RNA结合蛋白依赖的方式下映射snoRNA与目标RNA的相互作用	Song, Z.	PDF	N/A	Mapping snoRNA-target RNA interactions in an RNA binding protein-dependent manner with chimeric eCLIP
# BioRxiv 2024-09-20 Papers

标题	作者	PDF链接	代码仓库	Title
PPARγ域间通讯的结构基础	Mosure, S. A.	PDF	N/A	Structural basis of interdomain communication in PPARγ
灵长类前额叶皮层中对扫视运动的预期性和回顾性表征	Calangiu, I.	PDF	N/A	Prospective and retrospective representations of saccadic movements in primate prefrontal cortex
用于分析和估计随机生化反应网络的滤波有限状态投影方法。	D'Ambrosio, E. S.	PDF	N/A	Filtered finite state projection method for the analysis and estimation of stochastic biochemical reaction networks.
膜嵌入的人类T细胞受体-CD3复合物在静息状态和配体结合状态下的结构	Notti, R. Q.	PDF	N/A	The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex
UGGT1介导的N-糖基化与不稳定的和错误折叠的糖蛋白的ER相关降解相竞争	Ninagawa, S.	PDF	N/A	UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
在不同啮齿动物杂交中，不同的复杂调控表型是导致杂交雄性不育的根源。	Hunnicutt, K. E.	PDF	N/A	Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses
在人类大脑进化和疾病过程中，KRAB锌指基因和转座子的调控网络发生了变化。	Chen, Y.-C.	PDF	N/A	Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease
利用信息几何对细胞表型过渡流形进行几何量化	Huang, M.	PDF	N/A	Geometric Quantification of Cell Phenotype Transition Manifolds with Information Geometry
在蛋白质结构约束下的基因重复功能多样化	Guo, K.	PDF	N/A	Functional Diversification of Gene Duplicates under the Constraint of Protein Structure
比较单细胞分析揭示了胎儿-母体界面细胞类型和细胞信号创新的复杂模式	Stadtmauer, D. J.	PDF	N/A	Comparative single cell analysis reveals complex patterns of cell type and cell signaling innovations at the fetal-maternal interface
伏隔核内侧壳中的胃泌素释放肽信号调节神经元兴奋性和动机	Aisenberg, E. E.	PDF	N/A	Gastrin-releasing peptide signaling in the nucleus accumbens medial shell regulates neuronal excitability and motivation
药物诱导的p53激活限制了胰腺癌的启动	Twardowski, J. J.	PDF	N/A	Drug-Induced p53 Activation Limits Pancreatic Cancer Initiation
加拉帕戈斯黄莺在应对交通噪音的行为可塑性方面，因与道路的距离不同而有所差异。	Hohl, L.	PDF	N/A	Galapagos yellow warblers differ in behavioural plasticity in response to traffic noise depending on proximity to road.
开发辣椒素衍生物作为抑制素配体，以调节癌细胞中的Aurora激酶A/PHB2相互作用	Djehal, A.	PDF	N/A	Development of capsaicin derivatives as prohibitin ligands to modulate the Aurora kinase A/PHB2 interaction in cancer cells
单等位基因表观遗传调控布氏锥虫中RNA聚合酶II多顺反子转录起始的双向沉默。	Kieft, R.	PDF	N/A	Mono-allelic epigenetic regulation of bi-directional silencing of RNA Polymerase II polycistronic transcription initiation in Trypanosoma brucei.
单核RNA测序揭示了纹状体小胶质细胞中急性应激和慢性运动的持久特征	Connolly, M. G.	PDF	N/A	Single-nucleus RNA sequencing reveals enduring signatures of acute stress and chronic exercise in striatal microglia
从人类多能干细胞可扩展地分化出下丘脑弓状核神经元，适用于代谢和生殖障碍的模型构建	Jovanovic, V. M.	PDF	N/A	Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders
鲁棒的结合能力和端粒结合蛋白的丧失是端粒重复基序进化的基础	Song, H.	PDF	N/A	Robust Binding Capability and Loss of Telomere-Binding Proteins Underlying the Evolution of Telomeric Repeat Motifs
一种即时语音合成神经假体	Wairagkar, M.	PDF	N/A	An instantaneous voice synthesis neuroprosthesis
评估预测哺乳动物皮层细胞类型特异性增强子的方法	Johansen, N. J.	PDF	N/A	Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex
高通量无监督量化模式在狨猴自然行为中的应用	Menegas, W.	PDF	N/A	High-throughput unsupervised quantification of patterns in the natural behavior of marmosets
外来入侵物种的灭绝潜力	Philippe-Lesaffre, M.	PDF	N/A	Extinction potential from invasive alien species
促性腺激素细胞具有双重起源，其中大多数在微青春期期间由垂体干细胞分化而来。	Sheridan, D.	PDF	N/A	Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty.
肌梭为运动序列提供灵活的感觉反馈。	Olson, W. P.	PDF	N/A	Muscle spindles provide flexible sensory feedback for movement sequences
RCoxNet：一种集成随机游走重启与突变及临床数据的癌症生存预测深度学习框架	Kumari, S.	PDF	N/A	RCoxNet: deep learning framework for enhanced cancer survival prediction integrating random walk with restart with mutation and clinical data
metagWGS，一个利用Illumina或PacBio HiFi读取数据进行宏基因组数据分析的综合工作流程	Mainguy, J.	PDF	N/A	metagWGS, a comprehensive workflow to analyze metagenomic data using Illumina or PacBio HiFi reads
在反思室和VR头戴设备环境中，对比呼吸练习与自然主义刺激对认知、行为和生理反应的影响：随机对照研究	Simonian, N.	PDF	N/A	Contrasting Cognitive, Behavioral, and Physiological Responses to Breathwork vs. Naturalistic Stimuli in Reflective Chamber and VR Headset Environments: Randomized Control Study
通过ER-Hoxb8条件性永生化巨噬细胞替代小胶质细胞，为深入了解Aicardi-Goutieres综合征的神经病理学提供了新的视角。	Nemec, K. M.	PDF	N/A	Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology
制造感知的生成模型架构能够实现生物序列的设计和合成，规模达到千万亿级	Weinstein, E. N.	PDF	N/A	Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale
氧化应激的隔离是必要的，但不足以得出姜黄素对多巴胺能神经的保护作用：来自ALSS果蝇帕金森病模型的见解	Phom, L.	PDF	N/A	Sequestration of oxidative is necessary but not sufficient enough to conclude dopaminergic neuroprotective efficacy of curcumin: Insights from ALSS Drosophila Parkinson disease model
结构系统发育学的一般替代矩阵。	Garg, S. G.	PDF	N/A	A general substitution matrix for structural phylogenetics.
使用质粒分析服务进行高效且经济的长时间读取扩增子测序：应用于日本牵牛花中的转座子插入等位基因	Nakagawa, S.	PDF	N/A	Labor- and cost-effective long-read amplicon sequencing using a plasmid analysis service: Application to transposon-inserted alleles in Japanese morning glory
对CLAP数据的重新分析证实了PRC2是一种RNA结合蛋白。	Lee, Y.	PDF	N/A	Re-analysis of CLAP data affirms PRC2 as an RNA binding protein
泛基因组启发的语言模型用于隐私保护的合成基因组序列生成	Huang, P.	PDF	N/A	Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation
SoyOD：一个综合的大豆多组学数据库，用于挖掘基因和生物学研究	Li, J.	PDF	N/A	SoyOD: An Integrated Soybean Multi-omics Database for Mining Genes and Biological Research
功能连接主要由非周期性的耦合，而非振荡性的耦合所主导。	Monchy, N.	PDF	N/A	Functional connectivity is dominated by aperiodic, rather than oscillatory, coupling
InTraSeq：一种揭示新型单细胞生物学和调控机制的多模态分析方法	Ariss, M. M.	PDF	N/A	InTraSeq: A Multimodal Assay that Uncovers New Single-Cell Biology and Regulatory Mechanisms
磷酸化诱导的SUMO化促进Ulk4在纤毛尖端的凝聚，以转导Hedgehog信号	Zhou, M.	PDF	N/A	Phosphorylation-induced SUMOylation promotes Ulk4 condensation at ciliary tip to transduce Hedgehog signal
细胞器向内运输推动纺锤体在秀丽隐杆线虫减数分裂期间向外迁移	Peraza, A. A.	PDF	N/A	Inward transport of organelles drives outward migration of the spindle during C. elegans meiosis
如何构建eDNA定制条形码参考库的最佳实践？以澳大利亚地下动物为例的研究。	Guzik, M.	PDF	N/A	What are the best practices for curating eDNA custom barcode reference libraries? A case study using Australian subterranean fauna.
对“蛋白质序列景观并不那么简单：关于无参考与基于参考推断”的回应	Park, Y.	PDF	N/A	Response to "Protein sequence landscapes are not so simple: on reference-free versus reference-based inference"
染色体外DNA与核凝聚物相关联，并通过重组染色质结构来增强致癌转录	Taghbalout, A.	PDF	N/A	Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription
将全长FLT1表达重定向至其可溶性异构体可促进缺血后血管生成	Bundalo, M.	PDF	N/A	Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis
用泛扩张显微镜可视化核孔复合体的可塑性	Morgan, K. J.	PDF	N/A	Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy
二硫键介导的TRAP1四聚化促进了其抗氧化和促肿瘤活性。	Faienza, F.	PDF	N/A	Disulfide-mediated tetramerization of TRAP1 fosters its antioxidant and pro-neoplastic activities.
通过地理信息学捕捉盐沼地下生物量的时空变化，这是关键的恢复力指标。	Runion, K. D.	PDF	N/A	Capturing spatiotemporal variation in salt marsh belowground biomass, a key resilience metric, through geoinformatics
不仅仅是果香：十二种番荔枝科植物的花部生物学、香气与光谱反射率	Liu, M.-F.	PDF	N/A	More than fruity scents: floral biology, scent and spectral reflectance of twelve Annonaceae species
揭示西尼罗病毒传播的温度敏感性：蚊媒病原体性状响应的新型计算方法	Heidecke, J.	PDF	N/A	Disclosing temperature sensitivity of West Nile virus transmission: novel computational approaches to mosquito-pathogen trait responses
AusAMF：澳大利亚丛枝菌根真菌群落数据库	Frew, A.	PDF	N/A	AusAMF: database of arbuscular mycorrhizal fungal communities in Australia
宿主异质性对流行病动态的影响取决于宿主传染性是如何确定的。	Cohen, J. A.	PDF	N/A	Effects of host heterogeneity on epidemiological dynamics are mediated by how host infectiousness is determined
树种多样性降低温带森林病原体损害：一项系统综述与元分析	Field, E.	PDF	N/A	Tree diversity reduces pathogen damage in temperate forests: a systematic review and meta-analysis
鱼类环境RNA测序通过短期水族箱采样灵敏地捕捉累积应激反应	Miyata, K.	PDF	N/A	Fish environmental RNA sequencing sensitively captures accumulative stress responses through short-term aquarium sampling
转录后调控IFI16促进在肺动脉高压中观察到的炎症性内皮病理表型	Rao, R. J.	PDF	N/A	Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension
大麻哈鱼虱（Lepeoptheirus salmonis）在斑点鲽（Cyclopterus lumpus）体内的消化时间与新鲜度、发育阶段及温度相关。	Eliasen, K.	PDF	N/A	The digestion time for salmon louse (Lepeoptheirus salmonis) in lumpfish (Cyclopterus lumpus) in relation to freshness, developmental stage, and temperature
全球基因型与环境预测竞赛揭示出，多样化的建模策略能够提供令人满意的玉米产量估算	Washburn, J. D.	PDF	N/A	Global Genotype by Environment Prediction Competition Reveals That Diverse Modeling Strategies Can Deliver Satisfactory Maize Yield Estimates
两种海蛄虾物种Echinogammarus marinus和Gammarus pulex在夜间光照水平逐渐增加下的行为节律	Underwood, C. N.	PDF	N/A	Behavioural rhythms of two gammarid species Echinogammarus marinus and Gammarus pulex under increasing levels of light at night
用于低剂量率瘤内放射治疗的掺钇-90金属有机框架（MOFs）	Qi, X.	PDF	N/A	Yttrium-90-doped metal-organic frameworks (MOFs) for low-dose rate intratumoral radiotherapy
通过在玻片上使用Mucinase StcE进行消化，对MUC2糖肽进行糖基位点映射和原位质谱成像	Lowery, S. C.	PDF	N/A	Glycosite Mapping and in situ Mass Spectrometry Imaging of MUC2 Glycopeptides via On-slide Digestion with Mucinase StcE
在拟南芥中，双酰胺的形成需要与DPH1相互作用的DPH2，以实现对光和氧化应激的抗性。	Kraemer, U.	PDF	N/A	Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance
新型调节因子Fpr2通过依赖于CCL4的中性粒细胞控制免疫稳态	Mei, S.	PDF	N/A	Novel regulator Fpr2 controls immune homeostasis via CCL4-dependent neutrophils
单纯疱疹病毒在感染小鼠皮肤后的组装与扩散	Richardo, T.	PDF	N/A	Herpes Simplex Virus Assembly and Spread in murine skin after infection from the outside
通过3,034个基因组的视角概述酿酒酵母的种群结构	Loegler, V.	PDF	N/A	Overview of the Saccharomyces cerevisiae population structure through the lens of 3,034 genomes
细菌和酵母表达系统中植物类病毒颗粒形成的研究	Balke, I.	PDF	N/A	Investigation of plant virus-like particle formation in bacterial and yeast expression systems
中枢突触前末梢通过限制再循环池密度来调节自发突触囊泡胞吐速率	Wilson, P.	PDF	N/A	Central Presynapses Regulate Spontaneous Synaptic Vesicle Exocytosis Rate by Constraining Recycling Pool Density
Cytoophidium复合物与细胞命运产生共鸣	Li, Y.-L.	PDF	N/A	Cytoophidium complexes resonate with cell fates
通过数学建模理解组织金属蛋白酶抑制剂对慢性伤口调节的作用	Dari, S.	PDF	N/A	Understanding the regulation of chronic wounds by tissue inhibitors of matrix metalloproteinases through mathematical modelling
关键物种对全球引入的强毒病原体的快速适应	Cassin-Sackett, L.	PDF	N/A	Rapid adaptation to a globally introduced virulent pathogen in a keystone species
葡甘露聚糖工程突显了半乳糖基化修饰在微调拟南芥细胞壁中纤维素-葡甘露聚糖相互作用中的作用。	Yoshimi, Y.	PDF	N/A	Glucomannan engineering highlights the role of galactosyl modification in fine-tuning cellulose-glucomannan interaction in Arabidopsis cell walls
聚集的巨噬细胞通过协调的入侵泡合作消除肿瘤。	Dooling, L. J.	PDF	N/A	Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia
网络驱动的不可苏拉姆新底物识别，用于靶向蛋白质降解	Jarnuczak, A. F.	PDF	N/A	Network-driven identification of indisulam neo-substrates for targeted protein degradation
Fusobacterium nucleatum通过三聚自转运粘附素CbpF与免疫细胞结合的结构基础	Marongiu, G. L.	PDF	N/A	Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF
一种用于生理条件下适冷物种生物学研究的高分辨率显微系统	Marty, A.-P. M.	PDF	N/A	A high-resolution microscopy system for biological studies of cold-adapted species under physiological conditions
单分子多重寿命成像与门控单光子相机	Ronceray, N.	PDF	N/A	Multiplexed lifetime imaging of single molecules with a gated single-photon camera
聚焦镓离子束的生物体积电子显微镜依赖于在断面形成抗辐射的富镓层。	Yang, Z.	PDF	N/A	Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face
通过HLA I类分子识别儿童脑瘤细胞表面呈现的天然寨卡病毒肽段	Sherwood, M.	PDF	N/A	Identification of natural Zika virus peptides presented on the surface of paediatric brain tumour cells by HLA classI
利用先验生物学知识推断和聚类突变特征的贝叶斯框架。	Buscaroli, E.	PDF	N/A	A Bayesian framework to infer and cluster mutational signatures leveraging prior biological knowledge.
急性髓系白血病中的PTPN11突变克隆层次结构	Fobare, S.	PDF	N/A	PTPN11 Mutation Clonal Hierarchy in Acute Myeloid Leukemia
15q11.2缺失相关神经发育障碍的人类神经元模型中的发育改变和网络连接性变化	Habela, C. W.	PDF	N/A	Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders
O-GlcNAc糖基化水平升高对齿状回中线粒体自噬和小胶质细胞的影响	Kramer, J.	PDF	N/A	Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus
小鼠中蛋白质O-GlcNAc糖基化的急性增加导致大脑转录组变化，这与在阿尔茨海默病中观察到的相反。	Bell, M.	PDF	N/A	Acute increase of protein O-GlcNAcylation in mice leads to transcriptome changes in the brain opposite to what is observed in Alzheimer Disease
Sca-1表达描绘了在稳态和病理条件下的小鼠中性粒细胞的促炎状态。	Nahiyera, M.	PDF	N/A	Sca-1 expression depicts pro-inflammatory murine neutrophils under steady state and pathological conditions
DNA-PK 调控环二核苷酸相关的一型干扰素反应	taffoni, c.	PDF	N/A	DNA-PK controls cyclic dinucleotide-associated type I Interferon responses
一项邻近连接分析筛选出SNAT2作为MARCH1 E3泛素连接酶的新型靶标	Balthazard, R.	PDF	N/A	A proximity ligation screen identifies SNAT2 as a novel target of the MARCH1 E3 ubiquitin ligase
植物逆转了养分添加对土壤多功能性抗旱性的积极影响	Piton, G.	PDF	N/A	Plants reverse the positive effect of nutrient addition on the drought resistance of soil multifunctionality
高通量氨基酸水平分析纤溶酶原激活剂抑制剂-1与不同变异蛋白酶相互作用的研究	Haynes, L. M.	PDF	N/A	High-throughput amino acid-level characterization of the interactions of plasminogen activator inhibitor-1 with variably divergent proteases
对一种极度濒危软体动物的突变率及其进化后果的直接测量	Wooldridge, B.	PDF	N/A	Direct measurement of the mutation rate and its evolutionary consequences in a critically endangered mollusk
酵母基因组数据库：基因组注释的进展、扩展的生化途径以及其他关键增强功能	Engel, S. R.	PDF	N/A	Saccharomyces Genome Database: Advances in Genome Annotation, Expanded Biochemical Pathways, and Other Key Enhancements
肝细胞癌的表观基因组分析揭示了异常的顺式调控变化和失调的逆转录转座子，这些变化具有预后潜力。	Cheng, C. C. Y.	PDF	N/A	Epigenomic analysis of hepatocellular carcinoma reveals aberrant cis-regulatory changes and dysregulated retrotransposons with prognostic potentials
一种新型高特异性和可溶性蛋白酶，用于精确去除N端纯化标签	Shams, R.	PDF	N/A	A new highly specific and soluble protease for precise removal of N-terminal purification tags
Palmatine与DNA的主要结合模式	Gentile, M.	PDF	N/A	The predominant binding mode of Palmatine to DNA
先天免疫受体NLRX1：胶质母细胞瘤病理生理学的潜在调节因子	Meena, D.	PDF	N/A	Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology
引发剂对橡树幼苗防御白粉病的特异性机制	Sanchez-Lucas, R.	PDF	N/A	Elicitor specific mechanisms of defence priming in oak seedlings against powdery mildew
优化小鼠血脑屏障血管的富集，重点聚焦于采集后分析中的网络层次结构	Abdelazim, H.	PDF	N/A	Optimized Enrichment of Murine Blood-Brain Barrier Vessels with a Critical Focus on Network Hierarchy in Post-Collection Analysis
牛血液树突状细胞和单核细胞亚群中XCR1、CX3CR1、CSF1R和ADGRE1的表达	Talker, S. C.	PDF	N/A	Expression of XCR1, CX3CR1, CSF1R and ADGRE1 on subsets of bovine blood dendritic cells and monocytes
极端微生物固定化核苷2'-脱氧核糖基转移酶用于核苷生物催化	Hernandez Martinez, S. A.	PDF	N/A	Immobilized Nucleoside 2'-Deoxyribosyltransferases from Extremophiles for Nucleoside Biocatalysis
潜在的癌症生物标志物：有丝分裂期DNA损伤检查点基因	Agarwal, K.	PDF	N/A	Potential Cancer Biomarkers: Mitotic Intra-S DNA Damage Checkpoint Genes
scaLR：一个基于低资源深度神经网络的单细胞分析与生物标志物发现平台	Jogani, S.	PDF	N/A	scaLR: a low-resource deep neural network-based platform for single cell analysis and biomarker discovery
基于花序逆转的日中性大麻（Cannabis sativa L.）微繁殖技术	Tabatabaei, D. S.	PDF	N/A	Floral Reversion based micropropagation of Day-Neutral Cannabis sativa L.
专业学会支持的生物学教育DEI研究的系统综述：该领域的研究群体、研究方法及分析层次	Idlebird, C.	PDF	N/A	A systematic review of professional society-backed biology education DEI research: The groups, research methods, and levels of analyses comprising the field
随机獾扑杀试验缺乏主动獾扑杀对牛结核病影响的证据：对Mills等人2024年研究（第一部分与第二部分）的评论	Torgerson, P.	PDF	N/A	Randomised Badger Culling Trial lacks evidence for proactive badger culling effect on tuberculosis in cattle: comment on Mills et al. 2024, Parts I & II
血管性认知障碍机制及相互作用的一个以炎症为中心的视角	Zeylan, M. E.	PDF	N/A	An Inflammation Centered Perspective to the Mechanisms and Interactions Related to Vascular Cognitive Impairment
BrainUnit：将物理单位融入高性能AI驱动的科学计算	Wang, C.	PDF	N/A	BrainUnit: Integrating Physical Units into High-Performance AI-Driven Scientific Computing
早期精神分裂症中的静息态超连接和低连接：我们应该关注冰山的哪一角？	Tomecek, D.	PDF	N/A	Resting-state hyper- and hypo-connectivity in early schizophrenia: which tip of the iceberg should we focus on?
器官特异性交感神经支配定义了内脏功能	Wang, T.	PDF	N/A	Organ-specific Sympathetic Innervation Defines Visceral Functions
从功能性磁共振成像数据解码参数化抓握力预期	Caccialupi, G.	PDF	N/A	Decoding Parametric Grip-Force Anticipation from fMRI-Data
特征基因揭示了小鼠和鱼类大脑发育过程中不变的全球空间模式	Kerstjens, S.	PDF	N/A	Eigengene reveals invariant global spatial patterns across mouse and fish brain development
增加早期内体适配器APPL1的神经元表达会导致内体和突触功能障碍，伴随胆碱能神经退化。	Jiang, Y.	PDF	N/A	Increased neuronal expression of the early endosomal adaptor APPL1 leads to endosomal and synaptic dysfunction with cholinergic neurodegeneration
社会结构对和尚鹦鹉发声灵活性的影响	Smeele, S. Q.	PDF	N/A	The effect of social structure on vocal flexibility in monk parakeets
传入感觉噪声对连续吸引子网络模型中网格状放电和路径整合的双重影响	Nagaraj, H.	PDF	N/A	Dichotomous impact of afferent sensory noise on grid-patterned firing and path integration in a continuous attractor network model
哺乳动物视网膜双极细胞：兔视网膜的形态学鉴定与系统分类，并进行比较视角的探讨	Famiglietti, E. V.	PDF	N/A	Mammalian Retinal Bipolar Cells: Morphological Identification and Systematic Classification in Rabbit Retina, with a Comparative Perspective
证据表明Dmrta2在小鼠皮层祖细胞中作为Pax6的转录抑制因子，并鉴定出与人类小头畸形相关的关键DNA识别突变	Shen, X.	PDF	N/A	Evidence that Dmrta2 acts as a transcriptional repressor of Pax6 in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in human
毛细血管尺度的微血管成像：高频超声定位显微镜在小鼠大脑中的应用	Lowerison, M.	PDF	N/A	Capillary-scale Microvessel Imaging with High-frequency Ultrasound Localization Microscopy in Mouse Brain
模式化的无线经颅光遗传学技术能够产生人工感知	Wu, M.	PDF	N/A	Patterned wireless transcranial optogenetics generates artificial perception
猕猴腹侧顶内皮层的功能连接模式揭示了一种前-后向的特化，类似于人类腹侧顶内皮层区域所描述的特征。	Sheng, W.-A.	PDF	N/A	The macaque ventral intraparietal functional connectivity patterns reveal an anterio-posterior specialization mirroring that described in human ventral intraparietal area
出生后前六个月大脑网络的空间发展	Seraji, M.	PDF	N/A	Spatial Development of Brain Networks During The First Six Postnatal Months
活体脑片中模拟缺血通过打开Na+/K+泵来模拟：对扩散性去极化生成的线索。	Kim, D.	PDF	N/A	Simulated ischemia in live cerebral slices is mimicked by opening the Na+/K+ pump: clues to the generation of spreading depolarization.
T1234：一种针对高分辨率fMRI数据配准错误的畸变匹配结构扫描解决方案	Kan, C.	PDF	N/A	T1234: A distortion-matched structural scan solution to misregistration of high resolution fMRI data
探索同步的边缘：慢波侵蚀了行为猴子的静息活动	Pazienti, A.	PDF	N/A	Probing the edge of synchronization: Slow waves erode resting activity in behaving monkeys
动脉自旋标记灌注磁共振成像分析用于人类连接组项目生命周期老化与发展研究	Kirk, T. F.	PDF	N/A	Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies
神经元脂滴在维持全身能量稳态中发挥着保守且性别偏向的作用。	Manceau, R.	PDF	N/A	Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis
僵直性清醒巩固：10赫兹重复视觉刺激增强视觉学习的离线增益	Yang, X.-Y.	PDF	N/A	Tetanizing wakeful consolidation: ten-hertz repetitive visual stimulation enhances the offline gain of visual learning
人类多巴胺能神经元携带LRRK2 G2019S突变的细胞内和细胞外蛋白质组特征	Knab, F.	PDF	N/A	The Cellular and Extra-Cellular Proteomic Signature of Human Dopaminergic Neurons Carrying the LRRK2 G2019S Mutation
在人类多巴胺能神经元中的形态学分析表明，线粒体解偶联具有神经保护作用。	Gorgogietas, V.	PDF	N/A	Morphological profiling in human dopaminergic neurons identifies mitochondrial uncoupling as a neuroprotective effect
在皮质发育过程中对Emx2和Dmrta2合作的新见解以及Dmrta2在脉络丛功能中的证据	Anirudhan, J.	PDF	N/A	Novel insights into Emx2 and Dmrta2 cooperation during cortex development and evidence for Dmrta2 function in choroid plexus
通过融合远端肾单位与输尿管芽，将收集系统整合入肾脏类器官。	Shi, M.	PDF	N/A	Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud.
调节DNA Polα可增强跨物种细胞重编程	Ranjan, R.	PDF	N/A	Modulating DNA Polα Enhances Cell Reprogramming Across Species
社交隔离加剧斑马鱼中adgrl3.1相关的外化和内化行为	Fontana, B. D.	PDF	N/A	Social Isolation Intensifies adgrl3.1-Related Externalizing and Internalizing Behaviors in Zebrafish
一种基于沙漠蚂蚁（Melophorus bagoti）导航行为的心理物理学视觉方法	deeti, s.	PDF	N/A	A Method for Visual Psychophysics based on the Navigational Behaviour of Desert Ants (Melophorus bagoti)
人类结构组合泛化的一种神经机制	Luettgau, L.	PDF	N/A	A neural mechanism for compositional generalization of structure in humans
在少数活跃神经元的情况下，群体编码中的偏差	Keemink, S. W.	PDF	N/A	Biases in population codes with a few active neurons
运动诱导的保留运动表现不伴有神经保护作用的小鼠帕金森病模型	Skelton, H. M.	PDF	N/A	Exercise Evokes Retained Motor Performance without Neuroprotection in a Mouse Model of Parkinson's Disease
人类视觉运动区域FST的功能定位	Wen, P.	PDF	N/A	Functional localization of visual motion area FST in humans
染色质重塑因子BRG1招募亨廷顿蛋白修复神经元中的DNA双链断裂	Pradhan, S.	PDF	N/A	Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons
一个统一的啮齿动物图谱揭示了背侧迷走复合体的细胞复杂性和进化分歧	Hes, C.	PDF	N/A	A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex
海马体中的γCaMKII多巴胺化促进了突触到核的信号传导和记忆形成	Stewart, A. F.	PDF	N/A	Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation
IGF-1和胰岛素受体在LepRb神经元中共同调节身体生长、骨质量、生殖和代谢。	Wang, M.	PDF	N/A	IGF-1 and insulin receptors in LepRb neurons jointly regulate body growth, bone mass, reproduction, and metabolism
米诺环素和N-乙酰半胱氨酸增加蛋白激酶Mζ表达，恢复小鼠闭合性脑损伤后的晚期长时程增强效应和空间学习能力	Nikulina, E.	PDF	N/A	Increased protein kinase Mζ expression by Minocycline and N-acetylcysteine restoreslate-phase long-term potentiation and spatial learning after closed head injury in mice
脊髓横断与运动速度对猫后肢肌肉协同作用的影响	Klishko, A.	PDF	N/A	EFFECTS OF SPINAL TRANSECTION AND LOCOMOTOR SPEED ON MUSCLE SYNERGIES OF THE CAT HINDLIMB
通过无监督分割和聚类惯性信号对啮齿动物行为进行精细分解	Fayat, R.	PDF	N/A	Fine decomposition of rodent behavior via unsupervised segmentation and clustering of inertial signals
工作记忆预测听觉序列的长期识别：已验证预测与预测误差之间的分离	Bonetti, L.	PDF	N/A	Working memory predicts long-term recognition of auditory sequences: Dissociation between confirmed predictions and prediction errors
血红蛋白α是一种氧化还原敏感的线粒体相关蛋白，存在于T淋巴细胞中。	Reed, E. C.	PDF	N/A	Hemoglobin alpha is a redox-sensitive mitochondrial-related protein in T-lymphocytes
ICOS限制了耗竭PD-1+ CD8 T细胞的记忆样特性和功能	Humblin, E.	PDF	N/A	ICOS limits memory-like properties and function of exhausted PD-1+ CD8 T cells
从摄取膨胀聚苯乙烯的黄粉虫幼虫（鞘翅目：拟步甲科）肠道中分离出的肺炎克雷伯菌	Caruajulca-Marin, L.	PDF	N/A	Klebsiella pneumoniae isolated from the intestines of Tenebrio molitor larvae (Coleoptera: Tenebrionidae) that consume expanded polystyrene
揭示铜绿假单胞菌对亚胺培南耐药性的蛋白质组学图谱：临床菌株与对照菌株的比较研究	Eidsaa, M.	PDF	N/A	Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains
1 白腿虾养殖中生产力的微生物组决定因素	Shan, X.	PDF	N/A	1 Microbiome determinants of productivity in whiteleg shrimp aquaculture
猴痘病毒蛋白质组的全面突变景观分析	Ozaktas, T.	PDF	N/A	Comprehensive Mutational Landscape Analysis of Monkeypox Virus Proteome
Mpox mRNA-1769疫苗抑制正痘病毒在鼻内、直肠和皮内接种部位的复制	Cotter, C. A.	PDF	N/A	Mpox mRNA-1769 Vaccine Inhibits Orthopoxvirus Replication at Intranasal, Intrarectal, and Cutaneous Sites of Inoculation
5'和3' UTRs在SARS-CoV-2基因组包装中的作用	Zhang, Z.	PDF	N/A	Involvement of 5' and 3' UTRs on SARS-CoV-2 Genome Packaging
化学修饰核苷类似物对SARS-CoV-2 RNA聚合酶的链终止效应	Yang, L.	PDF	N/A	Chain Termination Effects of Chemically Modified Nucleoside Analogs on SARS-CoV-2 RNA Polymerase
MdLRR-RLK1-MdATG3模块通过自噬增强苹果对非生物胁迫的抗性	Chen, W.-J.	PDF	N/A	MdLRR-RLK1-MdATG3 module enhances the resistance of apples to abiotic stress via autophagy
深度学习揭示了多模板PCR中序列特异性扩增偏倚	Gimpel, A. L.	PDF	N/A	Deep learning uncovers sequence-specific amplification bias in multi-template PCR
尿液蛋白质组中的病毒片段：发热病因的新线索	Gao, Y.	PDF	N/A	Viral fragments in the urine proteome: New clues to the cause of fever
外生菌根真菌黄孢乳牛肝菌（Suillus luteus）在原生和引入种群中的生物合成基因簇多样性	Allen, B. M.	PDF	N/A	Biosynthetic Gene Cluster Diversity Across Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus
野生环境中个体和群体社会行为的分级选择	Philson, C. S.	PDF	N/A	Multilevel selection on individual and group social behaviour in the wild
来自木质纤维素影响环境的高质量Bathyarchaeia宏基因组组装基因组揭示了代谢和进化机制。	Nesbo, c. L.	PDF	N/A	High quality Bathyarchaeia MAGs from lignocellulose-impacted environments elucidate metabolism and evolutionary mechanisms.
谷氨酸激酶的纤维化及脯氨酸抑制作用	Zhang, T.	PDF	N/A	Filamentation and proline inhibition of glutamate kinase
动态金属配位调控自由基卤化酶的化学选择性	Kissman, E. N.	PDF	N/A	Dynamic metal coordination controls chemoselectivity in radical halogenases
从大肠杆菌中高效生产功能性前溶菌素	Pham, Q.	PDF	N/A	Efficient production of functional proaerolysin from E.coli
一个内在无序的RNA结合区域提供了局部目标选择性，并且对LARP6的功能至关重要。	Capraro, F.	PDF	N/A	An intrinsically disordered RNA-binding region provides local target selectivity and is essential for LARP6 function.
鉴定出胱氨酸代谢调控因子（CymR）衍生的五肽作为金黄色葡萄球菌O-乙酰-ʟ-丝氨酸硫醇酶（CysK）的纳摩尔抑制剂	Pederick, J. L.	PDF	N/A	Identification of cysteine metabolism regulator (CymR)-derived pentapeptides as nanomolar inhibitors of Staphylococcus aureus O-acetyl-ʟ-serine sulfhydrylase (CysK)
羊双心室心力衰竭中的三尖瓣不适应：后叶和间隔叶	Kostelnik, C. J.	PDF	N/A	Tricuspid valve maladaptation in sheep with biventricular heart failure: The posterior and septal leaflets
设计和生物工程改造CDR，使其对SARS-CoV-2 Omicron变体的受体结合域（RBD）具有更高的亲和力	Singh, V.	PDF	N/A	Designing and bioengineering of CDRs with higher affinity against receptor-binding domain (RBD) of SARS-CoV-2 Omicron variant
TX-Phase：在可信执行环境中对私有基因组进行安全分阶段处理	Dokmai, N.	PDF	N/A	TX-Phase: Secure Phasing of Private Genomes in a Trusted Execution Environment
通过调节ROCK克服癌细胞对OXPHOS抑制的代谢适应，并驱动协同的抗肿瘤活性	Blazanin, N.	PDF	N/A	Therapeutic modulation of ROCK overcomes metabolic adaptation of cancer cells to OXPHOS inhibition and drives synergistic anti-tumor activity
长期饮食暴露于邻苯二甲酸盐混合物会增强雌激素和β-连环蛋白信号通路，导致小鼠子宫内膜增生。	Shukla, R.	PDF	N/A	Long-term dietary exposure to a mixture of phthalates enhances estrogen and beta-catenin signaling pathways, leading to endometrial hyperplasia in mice
特定情境下基因组规模代谢模型的修改与分析：以甲烷利用微生物底盘为例	Kulyashov, M. A.	PDF	N/A	Modification and Analysis of Context-Specific Genome-Scale Metabolic Models: Methane-Utilizing Microbial Chassis as a Case Study
# BioRxiv 2024-09-19 Papers

标题	作者	PDF链接	代码仓库	Title
一种由光触发的非经典平面细胞极性通路	Housset, M.	PDF	N/A	A non-canonical planar cell polarity pathway triggered by light
一种宿主内感染模型，用于探究耐受性和抗性	Duneau, D.	PDF	N/A	A within-host infection model to explore tolerance andresistance
一种探究宿主体内耐受性和抵抗力的感染模型	Duneau, D.	PDF	N/A	A within-host infection model to explore tolerance andresistance
在恶性疟原虫感染的红细胞中，一个不寻常的MSRP6转运域定义了一个复杂结构，该结构对于Maurer裂隙的锚定和维持是必需的。	Blancke Soares, A.	PDF	N/A	An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells
iTRVZ：用于整合细胞膜信号的纳米液态平台	Tsunoyama, T. A.	PDF	N/A	iTRVZ: liquid nano-platform for signal integration on the plasma membrane
通过人类心室电机械建模和模拟解释急性与慢性梗塞的临床表型	Zhou, X.	PDF	N/A	Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations
新型猪模型揭示肺发育和稳态过程中存在两种不同的LGR5细胞类型	Polkoff, K.	PDF	N/A	Novel porcine model reveals two distinct LGR5 cell types during lung development and homeostasis
使用深度学习预测代谢物对饮食干预的反应	Wang, T.	PDF	N/A	Predicting metabolite response to dietary intervention using deep learning
全基因组DNA修复蛋白的分析揭示了单细胞中更高层次的协调	de Luca, K. L.	PDF	N/A	Genome-wide profiling of DNA repair proteins identifies higher-order coordination in single cells
视觉皮层中多个移动刺激的神经表征中双眼视差和注意力的作用	Chakrala, A. S.	PDF	N/A	The role of binocular disparity and attention in the neural representation of multiple moving stimuli in the visual cortex
联想学习和非联想学习对防御行为动态的贡献	Le, Q.-S. E.	PDF	N/A	Contributions of associative and non-associative learning to the dynamics of defensive ethograms
在巨型基因组植物黑种草（Nigella damascena L.）的异染色质复制过程中，全球核重组。	Arifulin, E.	PDF	N/A	Global nuclear reorganization during heterochromatin replication in the giant-genome plant Nigella damascena L.
电影揭示了婴儿视觉皮层的精细结构	Ellis, C. T.	PDF	N/A	Movies reveal the fine-grained organization of infant visual cortex
认知努力增加了奖励的强度。	Wahab, M.	PDF	N/A	Cognitive effort increases the intensity of rewards
胎儿和成人胸腺中T细胞受体（TCR）基因片段的使用和MHC限制性存在明显差异。	Rowell, J.	PDF	N/A	Distinct T Cell Receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus
一种从延迟的消化后反馈中学习的神经机制	Zimmerman, C. A.	PDF	N/A	A neural mechanism for learning from delayed postingestive feedback
鳞头松鸡和北鹑的关键繁殖行为受温度变化和平均温度的影响。	Kirkpatrick, W.	PDF	N/A	Critical reproductive behaviors in Scaled Quail and Northern Bobwhite are affected by thermal variability and mean temperature
p53通过关联基因组完整性和衰老相关炎症的相互调控	Miller, K. N.	PDF	N/A	Linked regulation of genome integrity and senescence-associated inflammation by p53
基于微生物组的随机误差校正方法，用于从自我报告的饮食评估中得出的营养素谱	Wang, T.	PDF	N/A	Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments
人类理性地适应对不确定性的近似估计。	Pulcu, E.	PDF	N/A	Humans adapt rationally to approximate estimates of uncertainty
基准测试单个降解蛋白质的鉴定，以探索古代蛋白质的最佳搜索策略	Rodriguez Palomo, I.	PDF	N/A	Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins
利用AlphaFold进行高通量发现抑制性蛋白质片段	Savinov, A.	PDF	N/A	High-throughput discovery of inhibitory protein fragments with AlphaFold
基于假设的可解释神经网络用于基因间相互作用	Wang, S.	PDF	N/A	Hypothesis-driven interpretable neural network for interactions between genes
基于假设的可解释神经网络，用于基因间相互作用	Wang, S.	PDF	N/A	Hypothesis-driven interpretable neural network for interactions between genes
撒哈拉以南非洲地区疟原虫卵形体种群的基因组学研究	Carey-Ewend, K.	PDF	N/A	Population genomics of Plasmodium ovale species in sub-Saharan Africa
一种用于研究疟原虫主要毒力因子功能研究的系统	Cronshagen, J.	PDF	N/A	A system for functional studies of the major virulence factor of malaria parasites
细菌受体而非抗噬菌体防御机制决定了一对铜绿假单胞菌裂解噬菌体的宿主范围	Mueller, D. M.	PDF	N/A	Bacterial Receptors but Not Anti-Phage Defence Mechanisms Determine Host Range for a Pair of Pseudomonas aeruginosa Lytic Phages
人类膀胱癌中自然杀伤细胞功能障碍是由组织特异性抑制SLAMF6信号传导引起的	Farkas, A. M.	PDF	N/A	Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling
与发育滞育的丧失相关的趋同进化可能会促进蜜蜂的寿命延长。	Ferreira Santos, P. K.	PDF	N/A	Convergent evolution associated with the loss of developmental diapause may promote extended lifespan in bees
胎儿期接触酒精的幼儿，其大脑代谢和兴奋性的改变标志物与执行功能相关。	Perdue, M. V.	PDF	N/A	Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol in utero
纵向弯曲刚度和中底泡沫对跑步能量学的影响	Perry, D.	PDF	N/A	Effects of longitudinal bending stiffness and midsole foam on running energetics
人类出生组织产品作为非阿片类药物抑制术后疼痛	Zhang, C.	PDF	N/A	Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain
评估3xTg-AD小鼠海马中胶质细胞与神经元之间细胞间通讯在两个时间点的改变情况	Soelter, T. M.	PDF	N/A	Evaluation of altered cell-cell communication between glia and neurons in the hippocampus of 3xTg-AD mice at two time points
人类诺如病毒在人类肠道类器官中培养的见解	Ettayebi, K.	PDF	N/A	Insights into Human Norovirus Cultivation in Human Intestinal Enteroids
人类血液中携带有噬菌体组，其在克罗恩病中有所不同。	Lamy-Besnier, Q.	PDF	N/A	The human blood harbors a phageome which differs in Crohn's disease
当环境发生变化时，候鸟会通过观察社会上的收益差异来学习。	Chimento, M.	PDF	N/A	Immigrant birds learn from socially observed differences in payoffs when their environment changes
一种新型单体淀粉样β激活的信号通路通过抑制小胶质细胞调节大脑发育	Kwon, H.	PDF	N/A	A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia
GeneSpectra：一种跨物种细胞类型基因表达的上下文感知比较方法	Song, Y.	PDF	N/A	GeneSpectra: a method for context-aware comparison of cell type gene expression across species
贝叶斯系统发育自举法，应用于短树和分支	Lemoine, F.	PDF	N/A	The Bayesian Phylogenetic Bootstrap, Application to Short Trees and Branches
在小鼠中对SV2A PET配体UCB-J的临床前验证和动力学建模	Everix, L.	PDF	N/A	Preclinical validation and kinetic modelling of the SV2A PET ligand UCB-J in mice
社会气味促使海马CA2区位置细胞对社会刺激产生反应	Robson, E.	PDF	N/A	Social odors drive hippocampal CA2 place cell responses to social stimuli
一个表示紧张动作电位尖峰列的数学序列	Keum, D.	PDF	N/A	A Mathematical Sequence Representing Tonic Action Potential Spike Trains
距离预测的神经表征精度与算术表现相关	Zhao, H.	PDF	N/A	Neural Representation Precision of Distance Predicts Arithmetic Performance
腹侧视觉通路中细粒度图像和类别信息的范围与限制	Badwal, M. W.	PDF	N/A	The scope and limits of fine-grained image and category information in the ventral visual pathway
一种用于绘制活体人脑中微观水群和组织弛豫率的定量磁共振成像方法。	Filo, S.	PDF	N/A	A qMRI approach for mapping microscopic water populations and tissue relaxivity in the in vivo human brain.
生物信息学家、计算机科学家和遗传学家领导生物信息工具开发 - 哪一个更好？	Gardner, P. P.	PDF	N/A	A Bioinformatician, Computer Scientist, and Geneticist lead bioinformatic tool development - which one is better?
"大分化者"属的系统基因组学揭示了岛屿系统中普遍存在的谱系不完全排序、基因流和线粒体捕获现象	McCullough, J.	PDF	N/A	Phylogenomics of a genus of "Great Speciators" reveals rampant incomplete lineage sorting, gene flow, and mitochondrial capture in island systems
宿主与抗生素共同筛选出金黄色葡萄球菌更强的毒力	Su, M.	PDF	N/A	Host and antibiotic jointly select for greater virulence in Staphylococcus aureus
临界性是大脑功能的统一设定点吗？	Hengen, K. B.	PDF	N/A	Is criticality a unified set-point of brain function?
组胺干扰了小鼠的早期视觉处理	Tripodi, M.	PDF	N/A	Histamine interferes with the early visual processing in mice
特定特征的除法归一化改进了深度感知中自然图像的编码	Ni, L.	PDF	N/A	Feature-specific divisive normalization improves natural image encoding for depth perception
肩胛间棕色脂肪组织的交感神经支配并不是雄性饮食诱导的肥胖大鼠中OT引发的身体重量增加和脂肪减少的主要介质。	Edwards, M. M.	PDF	N/A	Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
对手在记忆回忆和视觉感知过程中，其视觉空间编码结构在中颞顶叶皮层中响应。	Scrivener, C. L.	PDF	N/A	Opponent visuospatial coding structures responses during memory recall and visual perception in medial parietal cortex
功能性磁共振成像显示，在大鼠大脑进行五天的局部高密度θ波爆发刺激（hdTBS）后，脑部活动的区域性变化。	Li, Q.	PDF	N/A	Functional MRI reveals regional changes of brain activity after five days of focal high-density theta burst stimulation (hdTBS) of the rat brain
通过DeepFuseNMF实现空间转录组学数据的可解释高分辨率降维	Tang, J.	PDF	N/A	Interpretable high-resolution dimension reduction of spatial transcriptomics data by DeepFuseNMF
pytom-match-pick：模板匹配中用于自动化分类的tophat-transform约束	Chaillet, M. L.	PDF	N/A	pytom-match-pick: a tophat-transform constraint for automated classification in template matching
利用高分辨率基因表达谱揭示了被子植物中全基因组加倍后的保守进化响应	Leal, J. L.	PDF	N/A	Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling
胞质CRISPR RNA用于RNA靶向CRISPR-Cas系统	Cheng, E. C. K.	PDF	N/A	Cytosolic CRISPR RNA for RNA-targeting CRISPR-Cas systems
基于转录程序的MET外显子14跳跃调控网络解析	Truong, M.-J.	PDF	N/A	Transcriptional program-based deciphering of the MET exon 14 skipping regulation network
一个从古代口腔微生物群中创建宏基因组组装基因组的高效流程	Standeven, F. J.	PDF	N/A	An efficient pipeline for creating metagenomic-assembled genomes from ancient oral microbiomes
揭示细胞内Raf抑制剂敏感性的机制基础，揭示协同联合治疗策略	Stoddard, E. G.	PDF	N/A	Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies
揭示细胞内Raf抑制剂敏感性的机制基础揭示了协同联合治疗策略	Stoddard, E. G.	PDF	N/A	Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies
贾第鞭毛虫蛋白酶体盖的二元蛋白质相互作用图谱揭示了GlRpn11的额外蛋白酶体功能	Das, A.	PDF	N/A	The binary protein interactome mapping of the Giardia lamblia proteasome lid reveals extra proteasomal functions of GlRpn11
从头设计主动旋转和摆动的球形微泡	Kaur, V.	PDF	N/A	De-novo design of actively spinning and gyrating spherical micro-vesicles
通过声波捕获进行生物聚合物凝聚物的机械表征	Nakajima, K.	PDF	N/A	Mechanical Profiling of Biopolymer Condensates through Acoustic Trapping
在肾脏中，通过相关超分辨率光学和电子显微镜技术对白蛋白进行定位	Birtasu, A. N.	PDF	N/A	Localization of Albumin with Correlative Super Resolution Light- and Electron Microscopy in the Kidney
Hcm1的动态磷酸化在慢性应激中促进适应性	Conti, M. M.	PDF	N/A	Dynamic phosphorylation of Hcm1 promotes fitness in chronic stress
细菌噬菌体在健康和克罗恩病中跨肠屏障的差异性易位	Douadi, C.	PDF	N/A	Differential translocation of bacteriophages across the intestinal barrier in health and Crohn's disease
开发一种细胞通透性强的生物素-HaloTag配体，以探究蛋白质变体在细胞代际间的功能差异	Yadav, A. K.	PDF	N/A	Development of a cell-permeable Biotin-HaloTag ligand to explore functional differences between protein variants across cellular generations
疾病状态在限制性迁移中的作用	Meid, A.	PDF	N/A	The role of disease state in confined migration
G蛋白偶联受体对mTORC1活性的底物特异性调控	Atkinson, S. J.	PDF	N/A	Substrate-specific regulation of mTORC1 activity by G protein-coupled receptors
RIPK1对于人类细胞中单纯疱疹病毒触发的依赖于ZBP1的坏死性凋亡是必不可少的。	Amusan, O. T.	PDF	N/A	RIPK1 is essential for Herpes Simplex Virus-triggered ZBP1-dependent necroptosis in human cells
CMK-1/CaMKI和TAX-6/Calcineurin在秀丽隐杆线虫的热回避回路中的拮抗作用，共同调控痛觉习惯化过程。	Rudgalvyte, M.	PDF	N/A	Antagonist actions of CMK-1/CaMKI and TAX-6/Calcineurin along the C. elegans thermal avoidance circuit orchestrate nociceptive habituation
通过定量和行为学研究，揭示了秀丽隐杆线虫觅食过程中的接受-拒绝决策机制。	Haley, J. A.	PDF	N/A	Accept-reject decision-making revealed via a quantitative and ethological study of C. elegans foraging
鼻内锂氯化物纳米颗粒抑制大脑炎症性细胞焦亡并改善5xFAD小鼠的记忆丧失和抑郁行为	Bhuiyan, P.	PDF	N/A	Intranasal Lithium Chloride Nanoparticles Inhibit Inflammatory Pyroptosis in Brains and Ameliorate Memory Loss and Depression Behavior in 5xFAD mice
伏隔核星形胶质细胞双向调节社会行为	VanRyzin, J. W.	PDF	N/A	Nucleus accumbens astrocytes bidirectionally modulate social behavior
皮层-海马相互作用是老年人基于图式的记忆编码的基础	Huang, S.	PDF	N/A	Cortico-hippocampal interactions underlie schema-supported memory encoding in older adults
猕猴的前侧额叶皮层在不同的学习情境中引导决策	Fujimoto, A.	PDF	N/A	Ventrolateral prefrontal cortex in macaques guides decisions in different learning contexts
神经元培养基中星形胶质细胞Nrf2的基础激活：神经元-星形胶质细胞建模的挑战与意义	Elsharkasi, M. M. O.	PDF	N/A	Basal activation of astrocytic Nrf2 in neuronal culture media: challenges and implications for neuron-astrocyte modelling
光遗传学刺激背侧纹状体双向控制癫痫发作	Hyder, S. K.	PDF	N/A	Optogenetic stimulation of dorsal striatum bidirectionally controls seizures
病毒介导的Oct4过表达与Notch信号通路的抑制协同作用，诱导哺乳动物Müller胶质细胞的神经发生能力。	Le, N.	PDF	N/A	Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Muller glia.
结合颊部质量平面力学和解剖特征，可以改进海兔摄食行为的神经力学建模。	Bennington, M. J.	PDF	N/A	Incorporating buccal mass planar mechanics and anatomical features improves neuromechanical modeling of Aplysia feeding behavior
淀粉样β调节小胶质细胞中硫胺素焦磷酸激酶-1表达的机制与后果	Cheng, X.	PDF	N/A	The mechanism and consequences of amyloid-β modulating thiamine pyrophosphokinase-1 expression in microglia
侧化的小脑连接在小回声定位鲸和非回声定位鲸的听觉通路中有所区别。	Flem, S. A.	PDF	N/A	Lateralized cerebellar connectivity differentiates auditory pathways in echolocating and non-echolocating whales
脊髓V1中间神经元的转录组图谱揭示了En1在运动输出特定元素中的作用	Trevisan, A. J.	PDF	N/A	The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output
人类黄斑的形成涉及通过CYP26A1调控的两波视黄酸信号抑制，这调节了细胞周期退出和视锥细胞的特化。	Harding, P.	PDF	N/A	Human macula formation involves two waves of retinoic acid signaling suppression via CYP26A1 regulating cell cycle exit and cone specification
Mylpf 剂量与斑马鱼胚胎中快肌纤维的大小成比例。	Adekeye, T. E.	PDF	N/A	Mylpf dosage is proportionate to fast-twitch myofibril size in the zebrafish embryo
Gα亚单位Gq/11家族对于下颌骨的发育是必要且充分的。	Kanai, S. M.	PDF	N/A	The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development
情感背景影响有蹄类动物的声纹特征	Osiecka, A. N.	PDF	N/A	Emotional contexts influence vocal individuality in ungulates
单个神经元电生理记录和计算模型可以预测章鱼手臂的运动。	Gedela, N. S. S.	PDF	N/A	Single unit electrophysiology recordings and computational modeling can predict octopus arm movement
黑色素瘤表面的陨石坑有助于肿瘤与免疫系统的相互作用，并在人类中显示出对检查点阻断的病理反应。	Ludin, A.	PDF	N/A	Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans
使用整骨颅骶疗法手动触发自主神经系统反应的特异性研究	Keller, M.	PDF	N/A	On the specificity of manual triggers of autonomic nervous system responses using osteopathic cranial manipulative medicine
FUS通过液-液相分离介导的MEF2和ETV5招募来控制肌肉分化和结构	Picchiarelli, G.	PDF	N/A	FUS controls muscle differentiation and structure through LLPS mediated recruitment of MEF2 and ETV5
环境挑战期间集体社会行为的神经基础	Raam, T.	PDF	N/A	Neural basis of collective social behavior during environmental challenge
对比认知、行为和生理反应：在反思室和VR头戴设备环境中，呼吸练习与自然主义刺激的效果	Simonian, N.	PDF	N/A	Contrasting Cognitive, Behavioral, and Physiological Responses to Breathwork vs. Naturalistic Stimuli in Reflective Chamber and VR Headset Environments
人类神经类器官微生理系统展示了基本学习和记忆所需的构建模块	Alam El Din, D.-M.	PDF	N/A	Human Neural Organoid Microphysiological Systems Show the Building Blocks Necessary for Basic Learning and Memory
α-突触核蛋白预形成纤维诱导的聚集和多巴胺能细胞死亡在组织蛋白酶D过表达和ZKSCAN3敲除小鼠中的研究	Mueller, T.	PDF	N/A	Alpha-synuclein preformed fibril-induced aggregation and dopaminergic cell death in cathepsin D overexpression and ZKSCAN3 knockout mice
光学神经影像工作室（OptiNiSt）：一个直观、可扩展、可扩展的光学神经影像数据分析框架	Yamane, Y.	PDF	N/A	Optical Neuroimage Studio (OptiNiSt): intuitive, scalable, extendable framework for optical neuroimage data analysis
母鼠催产素神经元活动的灵活调节通过微型内窥镜技术揭示	Yaguchi, K.	PDF	N/A	Flexible Adjustment of Oxytocin Neuron Activity in Mother Mice Revealed by Microendoscopy
网格细胞信息几何中的速度调制	Ye, Z.	PDF	N/A	Speed modulations in grid cell information geometry
删除PTEN（而不是SOCS3或髓鞘抑制因子）显著增强了BRAF诱导的外周感觉轴突脊髓内再生。	Kim, H.	PDF	N/A	Deleting PTEN, but not SOCS3 or myelin inhibitors, robustly boosts BRAF-elicited intraspinal regeneration of peripheral sensory axons
下丘脑内神经回路调控雄性小鼠交配射精后β-内啡肽的释放	Zha, X.	PDF	N/A	Intra-hypothalamic circuit orchestrates β-endorphin release following coital ejaculation in male mice
在小胶质细胞炎症中的铜的作用	Craciun, L.	PDF	N/A	Role of copper during microglial inflammation
黑质多巴胺能神经元动作电位形状及树突形态的产后发育	Moubarak, E. M.	PDF	N/A	Postnatal Development Of Dendritic Morphology And Action Potential Shape In Rat Substantia Nigra Dopaminergic Neurons
眼压升高会损害视神经乳头中的轴突运输，导致神经退行性变，这是在一种新型Cre诱导的肌动蛋白青光眼小鼠模型中发现的。	Kaipa, B. R.	PDF	N/A	Ocular hypertension impairs axonal transport in the optic nerve head leading to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucoma.
无监督对齐揭示了自然场景神经表征在个体和脑区之间的结构共性和差异	Takeda, K.	PDF	N/A	Unsupervised alignment reveals structural commonalities and differences in neural representations of natural scenes across individuals and brain areas
通过ER-Hoxb8条件性永生化巨噬细胞替代小胶质细胞，为深入了解Aicardi-Goutieres综合征的神经病理学提供了新的视角。	Nemec, K. M.	PDF	N/A	Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology
在经典条件反射过程中，小鼠纹状体纹状体成分中的多巴胺释放对奖励和厌恶结果的反应	Yoshizawa, T.	PDF	N/A	Dopamine release in striatal striosome compartments in response to rewards and aversive outcomes during classical conditioning in mice
利用经皮脊髓刺激开发和评估一种非侵入式脑-脊接口	Atkinson, C. J.	PDF	N/A	Development and evaluation of a non-invasive brain-spine interface using transcutaneous spinal cord stimulation
视觉词汇的大脑可塑性：小学教师可以在几周内推动的变化，与那些需要数年时间形成的变化相当。	Wang, F.	PDF	N/A	Brain plasticity for visual words: Elementary school teachers can drive changes in weeks that rival those formed over years
在心脏形成过程中，心包膜作为一个独特的结构形成。	Moran, H. R.	PDF	N/A	The pericardium forms as a distinct structure during heart formation
在心脏形成过程中，心包膜作为一个独立的结构形成。	Moran, H. R.	PDF	N/A	The pericardium forms as a distinct structure during heart formation
RFX3对于从多能干细胞衍生的人胰腺胰岛的发育和成熟至关重要。	Memon, B.	PDF	N/A	RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells
RFX3对于从多能干细胞衍生的人胰腺胰岛的发育和成熟至关重要。	Memon, B.	PDF	N/A	RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells
中央纺锤体促进秀丽隐杆线虫锚定细胞的特化、外阴诱导及形态发生。	Kato, T.	PDF	N/A	Centralspindlin promotes C. elegans anchor cell specification, vulva induction and morphogenesis
Sox10Dom/+ 先天性巨结肠小鼠模型中的单细胞分析揭示了 Hoxa6 在肠神经元谱系分配中的作用	Avila, J. A.	PDF	N/A	Single Cell Profiling in the Sox10Dom/+ Hirschsprung Mouse Implicates Hoxa6 in Enteric Neuron Lineage Allocation
Sox10Dom/+ 先天性巨结肠小鼠中单一细胞分析揭示 Hoxa6 在肠神经元谱系分配中的作用	Avila, J. A.	PDF	N/A	Single Cell Profiling in the Sox10Dom/+ Hirschsprung Mouse Implicates Hoxa6 in Enteric Neuron Lineage Allocation
在加利福尼亚中部城市环境中越冬的穴居猫头鹰（Athene cunicularia hypugaea）到达时间较晚，离开时间较早，偏好有遮蔽的微生境，能耐受雨水，并与多种捕食者竞争。	Nicolaus, M. A.	PDF	N/A	Athene cunicularia hypugaea wintering in a central California urban setting arrive later, leave earlier, prefer sheltered micro-habitat, tolerate rain, and contend with diverse predators
ECSFinder：从基因组序列中优化预测进化保守的RNA二级结构	Gaonac'h-Lovejoy, V. A.	PDF	N/A	ECSFinder: Optimized prediction of evolutionarily conserved RNA secondary structures from genome sequences
一项关于外生菌根真菌松乳菇（Suillus luteus）本地种群和引入种群局部适应性的实验测试	Allen, B. M.	PDF	N/A	An Experimental Test of Local Adaptation in Native and Introduced Populations of an Ectomycorrhizal Fungus, Suillus luteus
从头组装自私t超级基因揭示了有害的进化轨迹	Runge, J.-N.	PDF	N/A	De novo assembly of the selfish t supergene reveals a deleterious evolutionary trajectory
植物根部的细胞间定向运输	Jacquier, L.	PDF	N/A	Directional Cell-to-cell Transport in Plant Roots
欧洲凤尾鱼生态型形成由不同起源的结构变异和与南方谱系的遗传相互作用驱动	Meyer, L.	PDF	N/A	Ecotype formation in the European anchovy fuelled by structural variants of different origins and genetic interactions with a southern lineage
AyurPhenoClusters确定了罕见疾病的共同分子根源，并揭示了综合征条件下纤毛功能障碍。	Joshi, A.	PDF	N/A	AyurPhenoClusters define common molecular roots for rare diseases and uncover ciliary dysfunctions in syndromic conditions
DNFE：用于检测生物过程中临界点的有向网络流熵	Peng, X.	PDF	N/A	DNFE: Directed-network flow entropy for detecting the tipping points during biological processes
白垩纪-古近纪大规模灭绝事件中的四足动物物种-面积关系	Close, R. A.	PDF	N/A	Tetrapod species-area relationships across the Cretaceous-Paleogene mass extinction
综合转录组和代谢组分析揭示了中华蹄盖蕨鳞芽启动和发育的调控机制	Yu, A.	PDF	N/A	Integrated Transcriptome and Metabolome Analyses Reveal the Mechanism Regulating Bulbil Initiation and Development in Cystopteris chinensis
灵长类新皮层中是否存在普遍的局部场电位功率的光谱层级模式？	Mackey, C. A.	PDF	N/A	Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex?
灵长类新皮层中是否存在普遍的局部场电位功率光谱层级模式？	Mackey, C. A.	PDF	N/A	Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex?
β细胞外囊泡PD-L1作为1型糖尿病进展过程中CD8+ T细胞活性的新型调节因子及生物标志物	Rao, C.	PDF	N/A	Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes
番茄斑萎病毒促进了非媒介性蜘蛛螨种类（Tetranychus urticae 和 Tetranychus evansi）在整个番茄植株上的活动。	Gupta, V.	PDF	N/A	Tomato spotted wilt virus facilitates non-vector spider mite species (Tetranychus urticae and Tetranychus evansi) on whole tomato plants
不同农业混配助剂的生态毒性	Bonn, D.	PDF	N/A	Eco-toxicity of different agricultural tank-mix adjuvants
一种世界性植物在其原产地和引入地的气候适应性	Albano, L. J.	PDF	N/A	Adaptation to climate in the native and introduced ranges of a cosmopolitan plant
大多数野牛牛没有可检测到的野牛遗传祖先。	Shapiro, B.	PDF	N/A	Most Beefalo cattle have no detectable bison genetic ancestry
线粒体超氧阴离子在肠道中发挥作用，以延长寿命	Liontis, T.	PDF	N/A	Mitochondrial superoxide acts in the intestine to extend longevity
多重空间映射组织中的染色质特征、转录组和蛋白质	Guo, P.	PDF	N/A	Multiplexed spatial mapping of chromatin features, transcriptome, and proteins in tissues
基因组分析表明，菌株VE202-06不存在万古霉素耐药性转移的风险。	Watson, A. R.	PDF	N/A	Genomic Analyses Suggest No Risk of Vancomycin Resistance Transfer by Strain VE202-06
猴子预测美国大选	Jiang, Y.	PDF	N/A	Monkeys Predict US Elections
从有限数据预测蛋白质生物物理特性：通过NanoMelt研究纳米抗体热稳定性的案例	Ramon, A. E.	PDF	N/A	Prediction of protein biophysical traits from limited data: a case study on nanobody thermostability through NanoMelt
从有限数据预测蛋白质生物物理特性：通过NanoMelt研究纳米抗体热稳定性的案例分析	Ramon, A. E.	PDF	N/A	Prediction of protein biophysical traits from limited data: a case study on nanobody thermostability through NanoMelt
制造意识生成模型架构能够实现生物序列设计与合成达到千万亿次规模	Weinstein, E. N.	PDF	N/A	Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale
在植物中既充当隔离子又充当沉默子的小型DNA元件	Jores, T.	PDF	N/A	Small DNA elements that act as both insulators and silencers in plants
Th17细胞需要DNA修复传感器XPC来控制氧化性DNA损伤。	Leite, J. A.	PDF	N/A	Th17 cells require the DNA repair sensor XPC to control oxidative DNA damage
抗原漂移过程中H3流感血凝素蛋白的结构和免疫学特性分析	de Paiva Froes Rocha, R.	PDF	N/A	Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift
皮下脂肪组织中肥胖和2型糖尿病性别差异的转录组图谱	Moldovan, R. A.	PDF	N/A	Transcriptomic landscape of sex differences in obesity and type 2 diabetes in subcutaneous adipose tissue
基于硫醇-烯点击反应的策略，用于定制可注射聚合物-纳米颗粒水凝胶的性质，以实现治疗性递送	Bailey, S. J.	PDF	N/A	A thiol--ene click-based strategy to customize injectable polymer--nanoparticle hydrogel properties for therapeutic delivery
荧光pH敏感纳米传感器能够在高通量生物工艺制造中实现低体积的精确监测。	Besenyei, G. C.	PDF	N/A	Fluorescent pH-sensitive nanosensors enable precise low-volume monitoring in high-throughput bioprocess manufacturing
无标记完整硫酸乙酰肝素寡糖的糖组学分析	Maciej-Hulme, M. L.	PDF	N/A	Glycoinformatic profiling of label-free intact heparan sulfate oligosaccharides
通过原子级模拟探索生物分子凝聚物中的RNA不稳定机制	Boccalini, M.	PDF	N/A	Exploring RNA destabilization mechanisms in biomolecular condensates through atomistic Simulations
在治疗错误折叠疾病的潜在纳米抗体中，构象稳定性和结合亲和力之间缺乏权衡	Gomez-Mulas, A.	PDF	N/A	The lack of trade-off between conformational stability and binding affinity in a nanobody with therapeutic potential for a misfolding disease
利用人工神经网络实现分子动力学模拟轨迹的最优存储与便捷共享	Wasim, A.	PDF	N/A	Employing Artificial Neural Networks for Optimal Storage and Facile Sharing of Molecular Dynamics Simulation Trajectories
炎症增加以及内质网应激和翻译减少区分了1型糖尿病前症状期胰腺胰岛与非糖尿病病例	Swensen, A. C.	PDF	N/A	Increased Inflammation as well as Decreased Endoplasmic Reticulum Stress and Translation Differentiate Pancreatic Islets of Pre-symptomatic Stage 1 Type 1 Diabetes and Non-diabetic Cases
弓形虫慢性感染通过外周阿片受体信号传导降低内脏痛觉	Audibert, A.	PDF	N/A	Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling
含LOTUS结构域的蛋白PpLDCP3调控藓类植物小立碗藓的生殖细胞及散布单位的形成	Kermanov, A.	PDF	N/A	The LOTUS-domain containing protein PpLDCP3 controls germline and dispersal unit formation in the moss Physcomitrium patens
基于光纤布拉格光栅的非破坏性根系表型分析系统，采用ResNet预测	Binder, S.	PDF	N/A	Fiber Bragg grating based sensing system for non-destructive root phenotyping using ResNet prediction
早期分化被子植物中的基因组印记揭示了开花植物种子起始的古老机制	Florez-Rueda, A. M.	PDF	N/A	Genomic imprinting in an early-diverging angiosperm reveals ancient mechanisms for seed initiation in flowering plants
肌醇多磷酸盐调控绿藻莱茵衣藻中的弹性机制，以适应极端营养条件。	Bedera-Garcia, R.	PDF	N/A	Inositol polyphosphates regulate resilient mechanisms in the green alga Chlamydomonas reinhardtii to adapt to extreme nutrient conditions
植物对小麦瘿螨和小麦条锈病毒（WSMV）的反应：小麦对病毒耐受性的首次证据	Pingault, L.	PDF	N/A	Plant responses to wheat curl mites and wheat streak mosaic virus (WSMV): first evidence of virus tolerance in wheat
双链RNA对埃及列当（Phelipanche aegyptiaca）种子萌发的非特异性效应	Zainali, N.	PDF	N/A	Non-specific effect of double-stranded RNAs on Egyptian broomrape (Phelipanche aegyptiaca) seed germination
通过基于CRISPR/Cas9 RNP的植物体内基因编辑技术培育出的长保质期甜瓜	Sasaki, K.	PDF	N/A	A long shelf-life melon created via CRISPR/Cas9 RNP-based in planta genome editing
PGR5促进依赖能量的非光化学淬灭，以在波动光照下实现高效的C4光合作用。	Woodford, R.	PDF	N/A	PGR5 promotes energy-dependent non-photochemical quenching to enable efficient C4 photosynthesis under fluctuating light
在拟南芥中，昼夜和发育时间尺度上的稳定且动态的基因表达模式	Redmond, E. J.	PDF	N/A	Stable and dynamic gene expression patterns over diurnal and developmental timescales in Arabidopsis thaliana
通过基因组编辑调控下游保守非编码序列，优化TAWAWA1介导的水稻穗型结构	Kuroha, T.	PDF	N/A	Fine-Tuning TAWAWA1-Mediated Panicle Architecture by Genome Editing of a Downstream Conserved Noncoding Sequence in Rice
遮荫通过SPL16/SPL23介导的细胞分裂素途径抑制杨树茎的形成层活动	Wei, H.	PDF	N/A	Shade Inhibits Cambial Activity in Populus Stems by the SPL16/SPL23-Mediated Cytokinin Pathway
植物BCL-Domain同源物在SWI/SNF复合体的稳定性中发挥着保守的作用。	Candela-Ferre, J.	PDF	N/A	Plant BCL-Domain Homologues play a conserved role in SWI/SNF complex stability
绿色藻类在适应有限二氧化碳环境时，二氧化碳浓缩机制与光呼吸的联合运作	Dao, O.	PDF	N/A	Joint operation of the CO2 concentrating mechanism and photorespiration in green algae during acclimation to limiting CO2
拟南芥AtGELP53通过寡糖介导的信号调节多糖乙酰化和防御反应	Rastogi, L.	PDF	N/A	Arabidopsis AtGELP53 modulates polysaccharide acetylation and defense response through oligosaccharide-mediated signaling
在叶绿体中工程化Rubisco凝聚以调控植物光合作用	Chen, T.	PDF	N/A	Engineering Rubisco Condensation in Chloroplasts to Manipulate Plant Photosynthesis
利用番茄相关细菌群落进行细菌性枯萎病的生物防治	Tanaka, E.	PDF	N/A	Biocontrol of bacterial wilt disease using plant-associated bacterial communities in tomato
M2巨噬细胞来源的外泌体通过抑制髓系细胞中的I型干扰素信号，逆转了饮食诱导心肌梗死小鼠的心脏功能下降。	Ng, M.	PDF	N/A	M2 Macrophage Exosomes Reverse Cardiac Functional Decline in Mice with Diet-Induced Myocardial Infarction by Suppressing Type 1 Interferon Signaling in Myeloid Cells
多种平台稳定化的HIV-1 C亚型儿童包膜糖蛋白的设计与免疫原性研究	Kumar, S.	PDF	N/A	Design and immunogenicity of an HIV-1 clade C pediatric envelope glycoprotein stabilized by multiple platforms
脑内AAV给药后诱导的针对衣壳的抗体以剂量依赖的方式限制了第二次给药	Xu, Y.-G.	PDF	N/A	Antibodies against the capsid induced after intracranial AAV administration limits second administration in a dose dependent manner
TREM2-p53信号轴活动中的遗传变异决定了氧气诱导的肺损伤	Abe, Y.	PDF	N/A	Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-inducedlung injury
古DNA揭示了大西洋蓝鳍金枪鱼的历史人口下降和遗传侵蚀	Andrews, A. J.	PDF	N/A	Ancient DNA reveals historical demographic decline and genetic erosion in the Atlantic bluefin tuna
微气候传感器网络的工作流程：整合地理工具、统计数据和地方知识	Klinges, D. H.	PDF	N/A	A workflow for microclimate sensor networks: integrating geographic tools, statistics, and local knowledge
剖析热带雨林中的蚯蚓多样性	Goulpeau, A.	PDF	N/A	Dissecting earthworm diversity in tropical rainforests
软壳蛤（Mya arenaria）可传播癌症中的基因表达揭示了其在宿主感染和海水转移过程中的生存机制	Hart, S. F. M.	PDF	N/A	Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer
革兰氏阴性细菌中肽聚糖O-乙酰化的机制典型地体现了细菌MBOAT-SGNH酰基转移酶的作用方式。	Anderson, A. C.	PDF	N/A	The mechanism of peptidoglycan O-acetylation in Gram-negative bacteria typifies bacterial MBOAT-SGNH acyltransferases
LiverMap 管道用于人体肝脏的三维成像，揭示了肝硬化血管胆道结构的体积空间失调。	Fabyan, W. B.	PDF	N/A	LiverMap pipeline for 3D imaging of human liver reveals volumetric spatial dysregulation of cirrhotic vasculobiliary architecture
通过可编程熵在平衡态下的分子计算	Wang, B.	PDF	N/A	Molecular computation at equilibrium via programmable entropy
基于聚丙烯酰胺的抗菌共聚物，能够抵御典型抗药性机制，用于替代或挽救抗生素	Williams, S. C.	PDF	N/A	Polyacrylamide-based Antimicrobial Copolymers Immune to Typical Resistance Mechanisms to Replace or Rescue Antibiotics
QuickEd：基于边界与对齐的高性能精确序列比对	Doblas, M.	PDF	N/A	QuickEd: High-performance exact sequence alignment based on bound-and-align
对大规模生物医学数据进行聚类，以建模疾病进展和抗微生物药物抗性进化中的动态积累过程	Dauda, K. A.	PDF	N/A	Clustering large-scale biomedical data to model dynamic accumulation processes in disease progression and anti-microbial resistance evolution
全面绘制左旋多巴与帕金森病中铁代谢相互作用图谱	Wang, J.	PDF	N/A	Comprehensive mapping of the Interaction of levodopa and iron metabolism in Parkinson's disease
利用大型语言模型提升基于生物标志物的肿瘤学试验匹配	Al Khoury, N.	PDF	N/A	Enhancing Biomarker-Based Oncology Trial Matching Using Large Language Models
侧链化学编码的凝聚物固/液相变	Chen, F.	PDF	N/A	Sidechain chemistry-encoded solid/liquid phase transitions of condensates
蠕动泵触发的淀粉样蛋白形成表明剪切应力是淀粉样蛋白成核的在体风险因素	Goto, Y.	PDF	N/A	Peristaltic pump-triggered amyloid formation suggests shear stresses are in vivo risk factors of amyloid nucleation
负电荷，而非必需的磷酸化，是14-3-3蛋白识别配体所必需的	Kamayirese, S.	PDF	N/A	Negative Charges, Not Necessary Phosphorylation, are Required for Ligand Recognition by 14-3-3 Proteins
α-突触核蛋白高分辨率冷冻电镜结构测定 - 一种典型的淀粉样纤维	Sanchez, J. C.	PDF	N/A	High-Resolution Cryo-EM Structure Determination of α-Synuclein - A Prototypical Amyloid Fibril
张力诱导的变构构象变化抑制解释了动力蛋白-1的协调步进	Makino, T.	PDF	N/A	Tension-induced suppression of allosteric conformational changes explains coordinated stepping of kinesin-1
驱动蛋白的两个马达结构域的动力学调控协调其在微管上的步进运动	Niitani, Y.	PDF	N/A	Kinetic regulation of kinesin's two motor domains coordinates its stepping along microtubules
来自2型糖尿病患者的血浆外泌体可促进乳腺癌在患者来源的类器官中的侵袭性	Ennis, C. S.	PDF	N/A	Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
通过阻断FoxO3a的Neddylation，Epac1的药理学抑制对肺纤维化具有保护作用	Jankowski, K.	PDF	N/A	Pharmacological Inhibition of Epac1 Protects against Pulmonary Fibrosis by Blocking FoxO3a Neddylation
一种无需灌胃的小鼠口服葡萄糖耐量测试精细方案的验证	Pye, K. R.	PDF	N/A	Validation of a refined protocol for mouse oral glucose tolerance testing without gavage
RFdiffusion在预测真菌病原体与谷类作物间蛋白质相互作用中的应用	Haley, O. C.	PDF	N/A	Application of RFdiffusion to predict interspecies protein-protein interactions between fungal pathogens and cereal crops
细胞大小稳态的广义加法机制：对克隆增殖随机动力学的启示	Nieto, C.	PDF	N/A	A Generalized Adder mechanism for Cell Size Homeostasis: Implications for Stochastic Dynamics of Clonal Proliferation
合并逻辑模型：在急性髓系白血病建模中的应用	Li, L. X.	PDF	N/A	Merging logical models: An application in Acute Myeloid Leukemia modeling
WEE1抑制剂延缓了雌激素受体阳性乳腺癌对CDK4/6抑制剂和抗雌激素治疗的耐药性	He, W.	PDF	N/A	WEE1 inhibition delays resistance to CDK4/6 inhibitor and antiestrogen treatment in estrogen receptor-positive breast cancer
实验室条件下饲养智利小植绥螨的优化	Nguyen, H.	PDF	N/A	Optimization of rearing Transeius montdorensis under laboratory conditions
第三型分泌系统诱导的液泡膜机械穿孔	SWISTAK, L.	PDF	N/A	TYPE THREE SECRETION SYSTEM-INDUCED MECHANOPORATION OF VACUOLAR MEMBRANES
T6SS DNase效应因子通过激活cGAS-STING-TNF轴引发核DNA损伤，从而触发细胞凋亡。	Song, L.	PDF	N/A	A T6SS DNase effector induces nuclear DNA Damage to trigger apoptosis via activation of the cGAS-STING-TNF axis
不同生活方式在真菌界中的生物合成基因簇变异	Allen, B. M.	PDF	N/A	Variation in Biosynthetic Gene Clusters Among Lifestyles Across Kingdom Fungi
常见膳食蛋白质成分的N-糖组谱的鉴定与比较	Bolino, M.	PDF	N/A	Identification and comparison of N-glycome profiles from common dietary protein ingredients
高通量元分析抗菌肽以鉴定类别特异性治疗候选者：一种计算机方法	Agrawal, P.	PDF	N/A	High Throughput Meta-analysis of Antimicrobial Peptides for Characterizing Class Specific Therapeutic Candidates: An in-silico Approach
FLIMPA：一种适用于荧光寿命成像显微镜相量分析的多功能软件	Kapsiani, S.	PDF	N/A	FLIMPA: A versatile software for Fluorescence Lifetime Imaging Microscopy Phasor Analysis
染色体不稳定性增加辐射敏感性	Cosper, P. F.	PDF	N/A	Chromosomal instability increases radiation sensitivity
一种综合的超高效液相色谱-串联质谱（UHPLC-MS/MS）和提取方法，用于菠菜（Spinacia oleracea）中的黄酮类化合物	Dzakovich, M. P.	PDF	N/A	A Comprehensive UHPLC-MS/MS and Extraction Method for Spinach (Spinacia oleracea) Flavonoids
铬还原细菌Bacillus tropicus的特性及分子机制研究	Tuli, S. R.	PDF	N/A	Characterization and molecular insights of a chromium-reducing bacterium Bacillus tropicus
金黄色葡萄球菌噬菌体phi812的细胞附着与尾部收缩	Binovsky, J.	PDF	N/A	Cell attachment and tail contraction of S. aureus phage phi812
一种珊瑚肽对全球海洋病原体——溶珊瑚弧菌具有杀菌活性。	Aoyama, K.	PDF	N/A	A coral peptide has bactericidal activity against a global marine pathogen, Vibrio coralliilyticus
多通道游戏中复式网络上的合作演化	Basak, A.	PDF	N/A	Evolution of cooperation in multichannel games on multiplex networks
机器学习时代的整合建模：HADDOCK策略在CAPRI第47至55轮中的总结	Reys, V.	PDF	N/A	Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55
新鲜人视网膜单细胞RNA测序图谱揭示了一种新型视锥细胞亚型及细胞多样性	Yang, L.	PDF	N/A	Fresh Human Retinal scRNA-seq Atlas Reveals a Novel Cone Subtype and Cellular Diversity
固定剂灌注前后神经组织制备质量的比较研究	Meyer-Dilhet, G.	PDF	N/A	Comparative study of pre- and post-mortem perfusion of fixative for the quality of neuronal tissue preparation
零回波时间成像实现了在小鼠中进行全脑活动图谱绘制，同时避免了腹侧信号的损失。	Imamura, A.	PDF	N/A	Zero-echo time imaging achieves whole brain activity mapping without ventral signal loss in mice
果蝇中的神经元同步	Fernandez-Chiappe, F.	PDF	N/A	Neuronal synchronization in Drosophila
色素分散因子对蚊子宿主搜寻持久性的昼夜调节影响每日叮咬模式	Dong, L.	PDF	N/A	Circadian modulation of mosquito host-seeking persistence by Pigment-Dispersing Factor impacts daily biting patterns
生成一种可诱导的不稳定结构域Cre小鼠品系，以靶向疾病相关的小胶质细胞	Henningfield, C. M.	PDF	N/A	Generation of an inducible destabilized-domain Cre mouse line to target disease associated microglia
氧化应激的隔离是必要的，但不足以得出姜黄素对多巴胺能神经的保护作用：来自ALSS果蝇帕金森病模型的见解	Phom, L.	PDF	N/A	Sequestration of oxidative is necessary but not sufficient enough to conclude dopaminergic neuroprotective efficacy of curcumin: Insights from ALSS Drosophila Parkinson disease model
视觉引导伸手过程中参考框架间方向和距离的神经编码	Harris Caceres, A.	PDF	N/A	Neural Encoding of Direction and Distance across Reference Frames in Visually Guided Reaching
基于SENP2的α-突触核蛋白N端截短在路易体病理传播中的作用	Taguchi, K.	PDF	N/A	SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation
PARP1对ADP-核糖基化的全球重塑抑制了甲型流感病毒感染	Zhang, Z.	PDF	N/A	Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection
微生物硫氧化菌和氨氧化菌在沿海海底生态状态中的关键作用	Nilsen, T.	PDF	N/A	Key roles of microbial sulfur and ammonium oxidizers for the coastal seafloor ecological state
液滴测序揭示口腔生物膜外泌体中的毒力基因簇	Takano, S.	PDF	N/A	Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles
通过lncRNA T-UCstem1依赖于DKK1调控WNT信号通路，实现对胚胎发育的非细胞自主性控制	Coppola, A.	PDF	N/A	Non-cell-autonomous control of gastruloid development by the lncRNA T-UCstem1 through DKK1-dependent modulation of WNT signalling
从基因到模式：一个建模胚胎发育从转录调控中涌现的框架	Garcia-Guillen, J.	PDF	N/A	From Genes to Patterns: A Framework for Modeling the Emergence of Embryonic Development from Transcriptional Regulation
利用基因组和线粒体数据揭示的濒危物种西伯利亚鼯鼠（Pteromys volans）的种群结构	Ito dos Santos, F.	PDF	N/A	Population structure of the endangered Siberian flying squirrel (Pteromys volans) revealed by genomic and mitochondrial data
短期抗生素、诱导磁场与迁徙鸣禽的磁感应能力	Sherf, G.	PDF	N/A	Short-term antibiotics, induced magnetic field, and magnetic sensitivity in a migratory songbird
一种快速、廉价、无培养、普适性的细菌鉴定系统，采用内部转录间隔区靶向引物：一项原理验证研究	Asthana, V.	PDF	N/A	A rapid, inexpensive, culture-free, universal bacterial identification system using internal transcribed spacer targeting primers: a proof-of-principle study
DuReS：一个用于去噪基于实验性串联质谱代谢组学数据的R包	Banerjee, S.	PDF	N/A	DuReS: An R package for denoising experimental tandem mass spectrometry-based metabolomics data
晚发性阿尔茨海默病中内嗅皮层和海马基因的差异调控	Biswas, M.	PDF	N/A	DIFFERENTIAL REGULATION OF GENES IN ENTORHINAL CORTEX AND HIPPOCAMPUS IN LATE ONSET AD
CelloType：一种用于组织图像分割与分类的统一模型	Pang, M.	PDF	N/A	CelloType: A Unified Model for Segmentation and Classification of Tissue Images
单细胞多模态组学整合方法的多任务基准测试	Liu, C.	PDF	N/A	Multi-task benchmarking of single-cell multimodal omics integration methods
利用加权四联体分布增强全基因组数据物种树推断	Hasan, N. B.	PDF	N/A	Leveraging weighted quartet distributions for enhanced species tree inference from genome-wide data
轨迹引导的降维方法用于多样本单细胞RNA测序数据，揭示了具有生物学意义的样本间异质性	Zhuang, H.	PDF	N/A	Trajectory-guided dimensionality reduction for multi-sample single-cell RNA-seq data reveals biologically relevant sample-level heterogeneity
STAG2-PAXIP1/PAGR1轴抑制肺肿瘤发生	Ashkin, E. L.	PDF	N/A	A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis
分子磁共振成像检测锌分泌失调可早期发现胰腺导管腺癌病变及对KRASG12D抑制剂治疗的反应	Jordan, V. C.	PDF	N/A	Molecular Magnetic Resonance Imaging of Dysregulated Zinc Secretion Detects Early Pancreatic Ductal Adenocarcinoma Lesions and Response to KRASG12D Inhibitor Treatment
黑皮质素-4受体拮抗剂TCMCB07缓解化疗引起的厌食和体重下降	Zhu, X.	PDF	N/A	Melanocortin-4 receptor antagonist TCMCB07 alleviates chemotherapy-induced anorexia and weight loss
低强度电肌肉刺激对废用一周后大腿和小腿肌肉基因表达和表型的多向效应	Borzykh, A. A.	PDF	N/A	Multidirectional effect of low-intensity electrical myostimulation on gene expression and phenotype in thigh and calf muscles after one week of disuse
PMR4胼胝质合酶的缺失导致拟南芥和油菜对根肿病的抗性不依赖于水杨酸且具有广谱性	Luo, B.	PDF	N/A	Loss of PMR4 callose synthase results in salicylic acid-independent and broad-spectrum resistance to clubroot in Arabidopsis and Brassica napus
密度依赖性彩色扫描电子显微镜（DDC-SEM）。在钙化组织研究中的应用及视觉影响。	Tsolaki, E.	PDF	N/A	Density-Dependent Colour Scanning Electron Microscopy (DDC-SEM). Applications in the study of calcified tissues and visual impact.
体内酶选择系统的代谢生长耦合策略	Alter, T. B.	PDF	N/A	Metabolic growth coupling strategies for in vivo enzyme selection systems
通过建模评估植物生长与防御之间的权衡关系，探讨初级代谢与次级代谢之间的相互作用	Zrimec, J.	PDF	N/A	Evaluating plant growth-defence trade-offs by modelling the interaction between primary and secondary metabolism
Cnes2b 调控宿主对隐球菌感染的抵抗力、炎症反应及组织损伤	Angers, I.	PDF	N/A	Cnes2b Regulates Host Resistance, Inflammatory Responses and Tissue Damage Following Cryptococcus deneoformans Infection
缺氧介导的TLR7/9触发的人类浆细胞样树突状细胞（PDC）衍生的IFN-α反应的精细调控是通过细胞内和可溶性IFN调节因子的联合作用实现的。	Lenkewitz, A.	PDF	N/A	Hypoxia-mediated fine-tuning of the TLR7/9-triggered human PDC-derived IFN-α response is mediated by combined cellular and soluble IFN-regulators
在斑马鱼神经杆内局部光遗传激活NMYII会导致长距离、不对称的力传播	Crellin, H. A.	PDF	N/A	Local optogenetic NMYII activation within the zebrafish neural rod results in long-range, asymmetric force propagation
意外的是，一种多蚁后超级基因单倍型在蚁群超群体的Formica蚂蚁种群中缺失。	Lagunas-Robles, G.	PDF	N/A	Unexpected absence of a multiple-queen supergene haplotype from supercolonial populations of Formica ants
性别、发育和营养依赖的北大西洋鲑鱼主要成熟年龄基因表达	Asheim, E. R.	PDF	N/A	Sex-, development-, and nutrition-dependent expression of a major age-at-maturity gene in Atlantic salmon
番木瓜（番木瓜科）性别决定相关单核苷酸变异效应的预测	Spelta, J. V. V. B.	PDF	N/A	PREDICTION OF SINGLE NUCLEOTIDE VARIANT EFFECTS RELATED TO SEX DETERMINATION IN Carica papaya (Caricaceae)
在存在胞嘧啶转换错误的情况下进行亚硫酸氢盐测序	Ellis, T. J.	PDF	N/A	Bisulphite sequencing in the presence of cytosine-conversion errors
抗菌潜力与圣罗勒提取物合成银纳米粒子的表征	Sulaiman, M.	PDF	N/A	Antimicrobial Potential and Characterization of Silver Nanoparticles Synthesized from Ocimum Sanctum Extract
滤波器组公共空间模式与基于包络的特征在多模态EEG-fTCD脑机接口中的应用	Khalaf, A.	PDF	N/A	Filter bank common spatial pattern and envelope-based features in multimodal EEG-fTCD brain-computer interfaces
管道奥运会：针对DNA甲基化测序数据的计算工作流程的可连续基准测试，与实验金标准进行对比	Lin, Y.-Y.	PDF	N/A	Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard
低级别胶质瘤中IDH1状态和1p/19q共缺失分类的放射组学与连接组学方法比较研究	Paradkar, R. V.	PDF	N/A	A Comparative Study of Radiomic and Connectomic Approaches to Classification of IDH1 Status and 1p/19q Co-deletion in Lower Grade Gliomas
GWA-X：一个可扩展的GPU加速包，用于全基因组关联研究中的排列检验	Agung, M.	PDF	N/A	GWA-X: An Extensible GPU Accelerated Package for Permutation Testing in Genome-Wide Association Studies
利用公开的数据非依赖性采集数据集对人类组织中基线蛋白质表达的综合视图	Prakash, A.	PDF	N/A	Integrated View of Baseline Protein Expression in Human Tissues using public Data Independent Acquisition datasets
Humatch - 快速、基因特异性抗体重链和轻链联合人源化	Chinery, L.	PDF	N/A	Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains
利用HetSIREN在实空间中对CryoEM构象状态进行异质性重构、精炼与解耦	Herreros, D.	PDF	N/A	Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIREN
SIRPalpha+ PD-L1+ 骨髓巨噬细胞通过调节T细胞功能促进AML生长	Birch, F.	PDF	N/A	SIRPalpha+ PD-L1+ bone marrow macrophages aid AML growth by modulating T cell function
水通道蛋白-4的表达水平和定位异常与不同侵袭性胶质瘤的瘤周水肿呈负相关。	Valente, O.	PDF	N/A	Aquaporin-4 expression levels and mis-localization are inversely linked to peritumoral edema in gliomas of varying aggressiveness
DNA聚合酶θ介导的DNA修复是DNMT3A缺陷型白血病细胞的功能依赖性和治疗脆弱性	Le, B. V.	PDF	N/A	DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells
小鼠中PI3K持续激活和Pten缺失导致的睾丸性索间质肿瘤	Dinevska, M.	PDF	N/A	Testicular sex cord stromal tumors in mice with constitutive activation of PI3K and loss of Pten
TAU 20成功刺激心肌神经节丛，且未造成心脏损伤	Li, S.	PDF	N/A	Successful stimulation of myocardial ganglionic plexuses by TAU 20 in the absence of cardiac damage
代谢建模揭示了IBD中宿主-微生物组代谢网络的多层次失调	Taubenheim, J.	PDF	N/A	Metabolic modeling reveals a multi-level deregulation of host-microbiome metabolic networks in IBD
心脏-肿瘤模型中免疫检查点抑制剂治疗的最优控制	van der Vegt, S.	PDF	N/A	Optimal control of immune checkpoint inhibitor therapy in a heart-tumour model
阐明早期肠道干细胞对细菌感染的反应	Lebon, S.	PDF	N/A	Elucidating early intestinal stem cell response to bacterial infection
预测蛋白质靶向嵌合体的降解潜力	Petrou, A.	PDF	N/A	Predicting Degradation Potential of Protein Targeting Chimeras
BayesAge 2.0：一种用于预测转录组年龄的最大似然算法	Pellegrini, M.	PDF	N/A	BayesAge 2.0: A Maximum Likelihood Algorithm To Predict Transcriptomic Age
变体评分在不同选择体制下的表现取决于变体与基因以及基因与疾病之间的关系。	Finucane, H. K.	PDF	N/A	Variant scoring performance across selection regimes depends on variant-to-gene and gene-to-disease components
基于深度学习的基因扰动效应预测尚未超越简单的线性方法。	Ahlmann-Eltze, C.	PDF	N/A	Deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods
用于结构系统发育学的一般替代矩阵。	Garg, S. G.	PDF	N/A	A general substitution matrix for structural phylogenetics.
ArchMap：一个基于网络的平台，用于基于参考的单细胞数据集分析	Lotfollahi, M.	PDF	N/A	ArchMap: A web-based platform for reference-based analysis of single-cell datasets
基准测试酶中运输通道研究中的粗粒度模拟方法	Mandal, N.	PDF	N/A	Benchmarking coarse-grained simulation methods for investigation of transport tunnels in enzymes
细菌基因型预测的深度视频分析	Dabouei, A.	PDF	N/A	Deep Video Analysis for Bacteria Genotype Prediction
嘌呤相互作用在生物矿物晶体形状决定中的作用	Rothkegel, J.	PDF	N/A	The Role of Purine Interactions in Biogenic Crystal Shape Determination
肌肉纤维蛋白质组学揭示了性别和纤维类型特异性对阻力训练的适应	Moesgaard, L.	PDF	N/A	Muscle fiber proteomics reveals sex- and fiber type-specific adaptations to resistance training
共享选择和遗传结构共同驱动了长期实验杂交种群中显著可重复的进化	Owens, G. L.	PDF	N/A	Shared selection and genetic architecture drive strikingly repeatable evolution in long-term experimental hybrid populations
优化的CRISPR抑制和激活为斑马鱼系统生物学探索开辟了关键途径。	Barrientos, N. B.	PDF	N/A	Optimized CRISPR inhibition and activation opens key avenues for systematic biological exploration in zebrafish.
染色质折叠模式定义了单等位基因中TAD结构的基本语法	Messina, O.	PDF	N/A	Chromatin folding motifs define the basic grammar of TAD architecture in single alleles
人类4D核组结构与功能的综合视角	The 4D Nucleome Consortium,	PDF	N/A	An integrated view of the structure and function of the human 4D nucleome
一个可访问的平台，用于量化载细胞水凝胶中的氧气扩散，并将其应用于海藻酸盐固定的胰腺β细胞	Champion, K.	PDF	N/A	An accessible platform to quantify oxygen diffusion in cell-laden hydrogels and its application to alginate-immobilized pancreatic beta cells
稳健的CRISPR/dCas13 RNA阻断器能够特异性地干扰miRNA与其靶标的相互作用，并能拯救1型肌强直性营养不良病理	Hanifi, M.	PDF	N/A	Robust CRISPR/dCas13 RNA blockers specifically perturb miRNA-target interactions and rescue type 1 myotonic dystrophy pathology
蛋白质pKa的精确快速预测：蛋白质语言模型揭示序列-pKa关系	Xu, S.	PDF	N/A	Accurate and Rapid Prediction of Protein pKa: Protein Language Models Reveal the Sequence-pKa Relationship
一种战略性混合稳定聚合物，用于控制颗粒表面电荷，以增强粘液传输和细胞结合	Stevens, C. A.	PDF	N/A	A Strategic Blend of Stabilizing Polymers to Control Particle Surface Charge for Enhanced Mucus Transport and Cell Binding
降低硫化氢生物利用度有助于保留射血分数的心脏代谢性心力衰竭	Doiron, J.	PDF	N/A	Reduced Hydrogen Sulfide Bioavailability Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction
外周阿片受体拮抗作用可缓解芬太尼引起的心血管呼吸抑制，且无厌恶效应。	Ruyle, B.	PDF	N/A	Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects
SARS-CoV-2在皮肤上的存活及其从污染表面的转移	Pitol Garcia, A. K.	PDF	N/A	SARS-CoV-2 Survival on Skin and its Transfer from Contaminated Surfaces
Maf家族bZIP转录因子NRL与视网膜光感受器中的RNA结合蛋白及R环相互作用	Corso Diaz, X.	PDF	N/A	Maf-family bZIP transcription factor NRL interacts with RNA-binding proteins and R-loops in retinal photoreceptors
利用计算分子网络工具对亨特利亚伞形叶甲醇和生物碱提取物中的次生代谢物进行研究	Adedeji, R. A.	PDF	N/A	INVESTIGATION OF SECONDARY METABOLITES PRESENT IN METHANOLIC AND ALKALOIDAL EXTRACTS OF HUNTERIA UMBELLATA LEAVES USING COMPUTATIONAL MOLECULAR NETWORKING TOOL
唑类与非唑类药物激活白色念珠菌Pdr1调控通路的异同	Conway, T. P.	PDF	N/A	Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs
结构导向的工程改造：针对人类细胞靶向基因插入的I-F型CASTs	Lampe, G. D.	PDF	N/A	Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells
与导致人类疟疾的动物源病原体疟原虫（Plasmodium knowlesi）相关的病毒属于一个多样且未分类的病毒分类单元。	Petrone, M. E.	PDF	N/A	A virus associated with the zoonotic pathogen Plasmodium knowlesi causing human malaria is a member of a diverse and unclassified viral taxon
在免疫细胞命运转换过程中，IRF8和FOS增强子对的协同和拮抗作用	Klonizakis, A.	PDF	N/A	Synergistic and antagonistic activities of IRF8 and FOS enhancer pairs during an immune cell fate switch
亚塔霉素生物合成需要两种脱氧核糖核酸酶来实现毒素自我抗性。	Dorival, J.	PDF	N/A	Yatakemycin biosynthesis requires two deoxyribonucleases for toxin self-resistance
分子水平解析电梯型金属转运蛋白中的底物转运机制	Jafari, M.	PDF	N/A	Molecular insights into substrate translocation in an elevator-type metal transporter
HDgraphiX：一种用于可视化氢氘交换质谱数据的基于网络的工具	Vosper, K. R.	PDF	N/A	HDgraphiX: A web-based tool for visualization of hydrogen deuterium exchange mass spectrometry data
使用高分辨率质谱法进行小肠和粪便代谢组学分析的无靶向和半靶向代谢组学方法	TRONEL, a.	PDF	N/A	Untargeted and Semi-Targeted Metabolomics Approach for Profiling Small Intestinal and Fecal Metabolome Using High-Resolution Mass Spectrometry
构象灵活性是设计广谱人诺如病毒蛋白酶抑制剂的关键因素。	Pham, S. H.	PDF	N/A	Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors
克莱兰免疫印迹揭示了意想不到的半胱氨酸氧化蛋白质形式	Cobley, J. N.	PDF	N/A	Cleland Immunoblotting Unmasks Unexpected Cysteine Redox Proteoforms
SCA5突变在β-III-血影蛋白的血影蛋白重复域中的分子后果	Denha, S.	PDF	N/A	Molecular consequences of SCA5 mutations in the spectrin-repeat domains of beta-III-spectrin
人类核糖体通过延迟共翻译域对接来调节多结构域蛋白的生物合成。	Pellowe, G. A.	PDF	N/A	The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking
微晶电子衍射（MicroED）结构揭示了氟替卡松糠酸酯和氟替卡松丙酸酯的新功能见解	Lin, J.	PDF	N/A	MicroED Structures of Fluticasone Furoate and Fluticasone Propionate Provide New Insights to Their Function
人类半胱氨酸氧化还原蛋白质组型的计算分析揭示了新的见解	Cobley, J. N.	PDF	N/A	Computational Analysis of Human Cysteine Redox Proteoforms Reveals Novel Insights
在ATP依赖性转位酶SMARCAL1、ZRANB3和HLTF的作用下，DNA复制叉反转过程中DNA损伤的链依赖性旁路机制	Adolph, M. B.	PDF	N/A	Strand dependent bypass of DNA lesions during fork reversal by ATP-dependent translocases SMARCAL1, ZRANB3, and HLTF
高通量机器人分离人类iPS细胞克隆揭示了CRISPR-Cas9介导的相同遗传操作常导致同源纯合诱导	Takahashi, G.	PDF	N/A	High-throughput robotic isolation of human iPS cell clones reveals frequent homozygous induction of identical genetic manipulations by CRISPR-Cas9
高精度组装抛光与DeepPolisher	Mastoras, M.	PDF	N/A	Highly accurate assembly polishing with DeepPolisher
重新定义P环NTP酶早期进化中的功能连续性界限	Demkiv, A. O.	PDF	N/A	Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases
红细胞内恶性疟原虫寄生虫消耗血红蛋白的噪音：起源及可能的影响	Perko, J. R.	PDF	N/A	Noisy hemoglobin consumption by erythrocytic Plasmodium falciparum parasites: origins and possible implications
对两种锰氧化酶的种群水平控制扩展了细菌锰生物矿化的生态位	Gehin, G.	PDF	N/A	Population-level control of two manganese oxidases expands the niche for bacterial manganese biomineralization
胶质细胞源性神经营养因子家族受体α样蛋白（GFRAL）的表达仅限于尾部脑干。	Hes, C.	PDF	N/A	GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem
一种基于草甘膦的除草剂在保留淡水细菌浮游生物群落内物种多样性的同时，选择性地促进了遗传变异。	Derrick, E.	PDF	N/A	A glyphosate-based herbicide selects for genetic changes while retaining within-species diversity in a freshwater bacterioplankton community
在果蝇细胞中使用整合和抗CRISPR（IntAC）技术进行的高分辨率全基因组CRISPR敲除筛选	Viswanatha, R.	PDF	N/A	Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC)
东非的“同一个健康”：产ESBL大肠杆菌的传播或独立抗菌素耐药基因在生态区间流动无障碍	Musicha, P.	PDF	N/A	One Health in Eastern Africa: No barriers for ESBL producing E. coli transmission or independent antimicrobial resistance gene flow across ecological compartments
隐形荧光蛋白渲染：基因编码的4-氰色氨酸保留其结构并实现配体结合位点的检测	Qianzhu, H.	PDF	N/A	Rendering Proteins Fluorescent Inconspicuously: Genetically Encoded 4-Cyanotryptophan Conserves Their Structure and Enables the Detection of Ligand Binding Sites
细胞内处理技术能够对低输入量的秀丽隐杆线虫进行快速且深入的蛋白质组分析。	Elsayyid, M.	PDF	N/A	In-cell processing enables rapid and in-depth proteome analysis of low-input Caenorhabditis elegans
# BioRxiv 2024-09-18 Papers

标题	作者	PDF链接	代码仓库	Title
囊泡和非囊泡外泌体小RNA在植物相互作用细菌中指导基因沉默	RAVET, A.	PDF	N/A	Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium
解开皮质电路中多类中间神经元的稳定性和增益调制	Bos, H.	PDF	N/A	Untangling stability and gain modulation in cortical circuits with multiple interneuron classes
自体受精脊椎动物中基因型和个体发育阶段的自体可育性变异	Gresham, J. D.	PDF	N/A	Variation in self-compatibility among genotypes and across ontogeny in a self-fertilizing vertebrate
基于细胞外基质的简单代理建模框架	Metzcar, J.	PDF	N/A	A simple framework for agent-based modeling with extracellular matrix
多组学图谱辅助发现选择性T细胞状态编程的转录因子	Chung, H. K.	PDF	N/A	Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming
IL-13促进哮喘中感觉神经与交感神经的相互作用	Crosson, T.	PDF	N/A	IL-13 promotes sensory-sympathetic neurons crosstalk in asthma
单一感觉的视觉和听觉对象在嗅觉皮层中得到处理，与气味关联无关。	Thunell, E.	PDF	N/A	Unisensory visual and auditory objects are processed in olfactory cortex, independently of odor association
DGRPool：一种利用协调的果蝇遗传参考面板表型数据研究复杂性状的网络工具	Gardeux, V.	PDF	N/A	DGRPool: A web tool leveraging harmonized Drosophila Genetic Reference Panel phenotyping data for the study of complex traits
进化基因组学预测了高山森林关键树种对气候变化的适应性遗传和可塑性基因表达反应	Long, Z.	PDF	N/A	Evolutionary genomics predicts adaptive genetic and plastic gene expression responses to climate change in a key alpine forest tree species
未来的抗生素在革兰氏阴性病原体中容易产生抗药性。	Daruka, L.	PDF	N/A	Antibiotics of the future are prone to resistance in Gram-negative pathogens
主要人类诺如病毒的依赖RNA的RNA聚合酶会形成液-液相分离凝聚体，作为病毒复制工厂。	Kaundal, S.	PDF	N/A	RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as viral replication factories
膜脂质纳米域调节伤害感受器背根神经节神经元中的HCN起搏通道	Handlin, L. J.	PDF	N/A	Membrane Lipid Nanodomains Modulate HCN Pacemaker Channels in Nociceptor DRG Neurons
行为上无关的特征匹配增加了神经和行为工作记忆的读出	Karabay, A.	PDF	N/A	Behaviorally irrelevant feature matching increases neural and behavioral working memory readout
HybriSeq：基于探针的无设备单细胞RNA分析	Foyt, D.	PDF	N/A	HybriSeq: Probe-based Device-free Single-cell RNA Profiling
蜱虫的胞外囊泡在吸血过程中破坏表皮伤口愈合	Marnin, L.	PDF	N/A	Tick extracellular vesicles undermine epidermal wound healing during hematophagy
三种RING蛋白的不同且相互依赖的功能调控哺乳动物减数分裂中的重组	Ito, M.	PDF	N/A	Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis
人类RAD52的双环结构重塑复制叉，限制叉反转	Honda, M.	PDF	N/A	A double-ring of human RAD52 remodels replication forks restricting fork reversal
图神经网络在人类大脑网络中结构-功能耦合的群体共性和个体特异性效应	Chen, P.	PDF	N/A	Group-common and individual-specific effects of structure-function coupling in human brain networks with graph neural networks
骨骼肌卫星细胞利用肌腱生成基因Scleraxis指导再生	Bai, Y.	PDF	N/A	Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene Scleraxis to Instruct Regeneration
使用HaloTag技术在hiPSC衍生的单细胞和类器官中可视化PIEZO1的定位和活性	Bertaccini, G. A.	PDF	N/A	Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology
计算加速的P-糖蛋白抑制剂识别	McCormick, L. A.	PDF	N/A	Computationally accelerated identification of P-glycoprotein inhibitors
利用生物电化学电池从甜菜汁中发电	Shlosberg, Y.	PDF	N/A	Photoelectricity generation from beet juice in a bio-electrochemical cell
基于假设的可解释神经网络用于基因间相互作用	Wang, S.	PDF	N/A	Hypothesis-driven interpretable neural network for interactions between genes
蛋白质-配体结合亲和力预测：是否需要三维结合构象？	Wu, M.-H.	PDF	N/A	Protein-ligand binding affinity prediction: Is 3D binding pose needed?
内质网接触点促进含沙门氏菌液泡（SCV）的协调分裂	Chopra, U.	PDF	N/A	Endoplasmic Reticulum contact sites facilitate the coordinated division of Salmonella-containing vacuole (SCV)
肿瘤微环境噪声诱导的极化：巨噬细胞癌症免疫治疗的主要挑战。	Sierra, J.	PDF	N/A	Tumor microenvironment noise-induced polarization: the main challenge in macrophages' immunotherapy for cancer.
蛋白质组学和脂质组学血浆评估揭示加州海狮的软骨藻酸中毒生物标志物	Solosky, A. M.	PDF	N/A	Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions
分子媒人：植原体效应因子SAP54通过靶向MADS-box因子SVP，通过调节叶片对雄性存在的反应，增强了对多产雌性媒介的吸引力	Orlovskis, Z.	PDF	N/A	Molecular Matchmakers: Phytoplasma Effector SAP54 Targets MADS-Box Factor SVP to Enhance Attraction of Fecund Female Vectors by Modulating Leaf Responses to Male Presence
使用Sentence-BERT从预测数据库中提炼疾病相关的蛋白质水平微RNA靶标相互作用	Chen, B.	PDF	N/A	Refining Protein-Level MicroRNA Target Interactions in Disease from Prediction Databases Using Sentence-BERT
利用无人机系统和计算机视觉对涉禽进行近实时监测	White, E. P.	PDF	N/A	Near real-time monitoring of wading birds using uncrewed aircraft systems and computer vision
探索选择的多元信心	Solopchuk, O.	PDF	N/A	Multifaceted confidence in exploratory choice
恐惧记忆合作与竞争的时间规则	Madeira, N.	PDF	N/A	Temporal rules of fear memory cooperation and competition
同型相分离的直接和间接盐效应	MacAinsh, M.	PDF	N/A	Direct and Indirect Salt Effects on Homotypic Phase Separation
基于模型的浮萍生物发光报告基因活动昼夜节律生成分析	Horikawa, Y.	PDF	N/A	Model-based analysis of the circadian rhythm generation of bioluminescence reporter activity in duckweed
按蚊种群空间结构在冈比亚按蚊复合体中的变异	McCann, R. S.	PDF	N/A	Variation in spatial population structure in the Anopheles gambiae species complex
一年内皮层厚度、表面积和脑体积的个体内部稳定性	Wang, M.-Y.	PDF	N/A	The within-subject stability of cortical thickness, surface area, and brain volumes across one year
在许多研究中，可避免的假PSMC种群规模峰值时有发生。	Hilgers, L.	PDF	N/A	Avoidable false PSMC population size peaks occur across numerous studies
基因型与环境相互作用在基因调控中的作用，揭示了模式草本植物短柄草（Brachypodium distachyon）对土壤干燥的响应机制。	Yun, J.	PDF	N/A	Genotype by environment interactions in gene regulation underlie the response to soil drying in the model grass Brachypodium distachyon
突变扩展规律揭示，通过基因扩增实现加速进化需要空间结构化的种群增长。	Komarova, N.	PDF	N/A	Mutant scaling laws reveal that accelerated evolution via gene amplification requires spatially structured population growth
免疫检查点抑制后的细胞动力学	Lin, Z.	PDF	N/A	Cellular Dynamics Upon Immune Checkpoint Inhibition
从单一序列到进化轨迹：蛋白质语言模型捕捉SARS-CoV-2蛋白质序列的进化潜力	Lamb, K. D.	PDF	N/A	From a single sequence to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 protein sequences
ANASFV：一种用于非洲猪瘟病毒全基因组测序、组装和评估的工作流程	Li, K.	PDF	N/A	ANASFV: a workflow for ASFV whole genome sequencing, assembly, and evaluation
bam转录本的失稳终止了果蝇雌性生殖系分化的有丝分裂阶段	Samuels, T. J.	PDF	N/A	Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation
使用全原子模拟对错误建模的冷冻电镜RNA结构进行集合细化	Posani, E.	PDF	N/A	Ensemble Refinement of mismodeled cryo-EM RNA Structures Using All-Atom Simulations
撤回：木薯褐条病致病病毒间的种间重组	Astacio-Berrios, K.	PDF	N/A	WITHDRAWN: Interspecies recombination between cassava brown streak disease-causing viruses
蓝藻中m4C DNA甲基化对四吡咯生物合成的表观遗传调控	Schmidt, N.	PDF	N/A	Epigenetic control of tetrapyrrole biosynthesis by m4C DNA methylation in a cyanobacterium
分离的基底神经节输出通路与基因上不同的神经元亚类相对应。	Mendelsohn, A.	PDF	N/A	Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses
安第斯叶耳鼠（Phyllotis）的物种界限与杂交现象	Quiroga-Carmona, M.	PDF	N/A	Species limits and hybridization in Andean leaf-eared mice (Phyllotis)
泛基因组学用于理解Pectobacterium属中的原噬菌体动力学以及P. brasiliense辐射谱系的演化	Pardeshi, L. A.	PDF	N/A	Pangenomics to understand prophage dynamics in the Pectobacterium genus and the radiating lineages of P. brasiliense
丝虫精子发生过程中重组、X染色体失活及着丝粒蛋白的动态变化	Toubiana, W.	PDF	N/A	Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis
梅克尔细胞癌衍生的巨噬细胞移动抑制因子（MIF）可能促进慢性淋巴细胞白血病的持续存在。	Alencar, G. F.	PDF	N/A	Merkel cell carcinoma-derived macrophage migration inhibitory factor (MIF) may promote persistence of Chronic Lymphocytic Leukemia
在海马体的循环网络模型中，条形码活动能够实现高效的记忆绑定。	Fang, C.	PDF	N/A	Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding
Mouse-Geneformer：一种用于小鼠单细胞转录组的深度学习模型及其跨物种应用	Ito, K.	PDF	N/A	Mouse-Geneformer: A Deep Learning Model for Mouse Single-Cell Transcriptome and Its Cross-Species Utility
物体非刚性的各向异性：皮层各向异性的高层次感知结果	Maruya, A.	PDF	N/A	Anisotropy of object non-rigidity: High-level perceptual consequences of cortical anisotropy
LncRNA TAAL是糖尿病视网膜病变中通过Tie1介导的血管功能的调节因子	Ranjan, G.	PDF	N/A	LncRNA TAAL is a Modulator of Tie1-Mediated Vascular Function in Diabetic Retinopathy
MEK1/2激酶与c-Myc:MAX协同作用，防止人类多能干细胞中TERT受到多梳蛋白的抑制。	Kotian, S. T.	PDF	N/A	MEK1/2 kinases cooperate with c-Myc:MAX to prevent polycomb repression of TERT in human pluripotent stem cells
MAPK/ERK信号通路在胶质瘤中调控干扰素反应、T细胞招募，增强肿瘤-小胶质细胞间的相互作用，并推动免疫检查点阻断疗法的疗效。	Kim, K.-S.	PDF	N/A	MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy.
MAPK/ERK信号通路在胶质瘤中调节干扰素反应、T细胞招募，增强肿瘤与小胶质细胞的相互作用，并推动免疫检查点阻断疗法的疗效。	Kim, K.-S.	PDF	N/A	MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy.
蜱虫中单一的 ANP32 祖先位点创造了多种蛋白质变体，这些变体均支持 Thogoto 病毒聚合酶的功能。	Zhang, Z.	PDF	N/A	A single ancestral ANP32 locus in ticks creates multiple protein variants that all support the Thogoto virus polymerase
海马体中人口活动的稀疏性在三突触回路和背腹轴上是任务不变的。	Lee, J. Q.	PDF	N/A	Sparsity of population activity in the hippocampus is task-invariant across the trisynaptic circuit and dorsoventral axis
从前馈到反馈节奏的表征转变，在自然视觉中标志着现象学整合的指标。	Chen, L.	PDF	N/A	Representational shifts from feedforward to feedback rhythms index phenomenological integration in naturalistic vision
面部表情与颜色在调节ERP P3中的相互作用	Hasegawa, Y.	PDF	N/A	Interaction between facial expression and color in modulating ERP P3
一个涵盖5000年历史的考古牙结石数据集，用于古代人类口腔微生物组研究	Standeven, F. J.	PDF	N/A	An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research
一种慢性小鼠肺部鲍曼不动杆菌感染模型，可用于研究晚期毒力因子、长期抗生素治疗和多微生物感染。	Jackson-Litteken, C. D.	PDF	N/A	A chronic murine model of pulmonary Acinetobacter baumannii infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections
无细胞人乳头瘤病毒DNA在转移性或复发性宫颈癌中的监测：临床意义与治疗启示	Yin, Z.	PDF	N/A	Monitoring of Cell-free Human Papillomavirus DNA in Metastatic or Recurrent Cervical Cancer: Clinical Significance and Treatment Implications
肢体上的学习：一个旨在吸引高中生参与骨科的推广模块	Panebianco, C. J.	PDF	N/A	Learning on a Limb: An outreach module to engage high school students in orthopaedics
药物难治性癫痫中的性别特异性补体和细胞因子失衡：免疫脆弱性的生物标志物	Pinzon-Hoyos, N.	PDF	N/A	Sex-Specific Complement and Cytokine Imbalances in Drug-Resistant Epilepsy: Biomarkers of Immune Vulnerability
非平衡涨落-耗散定理为阿尔茨海默病研究铺平道路	Patow, G. A.	PDF	N/A	Off-Equilibrium Fluctuation-Dissipation Theorem Paves the Way in Alzheimer's Disease Research
阿尔茨海默病中默认模式网络功能障碍和认知衰退的神经生理学特征。	Ozdemir, R. A.	PDF	N/A	Neurophysiological signatures of default mode network dysfunction and cognitive decline in Alzheimer disease.
相机类型、高度及图像增强对浑浊海洋环境中摄影测量成功率的影响。	Savill, K. L.	PDF	N/A	Influence of camera type, height and image enhancement on photogrammetry success in turbid marine environments.
系统性CD8+ T细胞效应器特征预测肺癌免疫治疗预后	Sim, H.	PDF	N/A	Systemic CD8+ T cell effector signature predicts prognosis of lung cancer immunotherapy
支气管和鼻腔粘液的比较表征揭示了流感A病毒抑制的关键决定因素	Pohl, M. O.	PDF	N/A	Comparative Characterization of Bronchial and Nasal Mucus Reveals Key Determinants of Influenza A Virus Inhibition
Medin诱导人脑血管平滑肌细胞的促炎激活	Karamanova, N.	PDF	N/A	Medin Induces Pro-Inflammatory Activation of Human Brain Vascular Smooth Muscle Cells
CRISPR/Cas9诱导的断裂不足以打破番茄（Solanum lycopersicum）中烟草花叶病毒（ToMV）位点周围的连锁拖曳。	Grubben, J.	PDF	N/A	CRISPR/Cas9-induced breaks are insufficient to break linkage drag surrounding the ToMV locus of Solanum lycopersicum
豆科（Legume）安麦斯米亚族（Amherstieae）中的生态位保守性：来自热带柏林尼亚支系（Berlinia）和布劳恩尼亚支系（Brownea）的启示	Romero, I. C.	PDF	N/A	Niche conservatism in the Legume Amherstieae tribe: Insights from the tropical Berlinia and Brownea clades
非重组种群中选择性清除过程中的遗传多样性	Kaushik, S.	PDF	N/A	Genetic diversity during selective sweeps in non-recombining populations
一种用于治疗性RNA质量控制的纳米孔测序碱基识别的迭代优化方法	Wang, Z.	PDF	N/A	An Iterative Approach to Polish the Nanopore Sequencing Basecalling for Therapeutic RNA Quality Control
按蚊中分子Toll通路的多样性	Rhodes, V. L.	PDF	N/A	The molecular Toll pathway repertoire in anopheline mosquitoes
一种红色荧光Lifeact标记物用于研究足细胞中的肌动蛋白形态	Wiesner, E.	PDF	N/A	A Red Fluorescent Lifeact Marker to Study Actin Morphology in Podocytes
选择常染色体显性DFNA11耳聋突变激活上皮细胞中的Myo7A	Acharya, P.	PDF	N/A	Select autosomal dominant DFNA11 deafness mutations activate Myo7A in epithelial cells
靶向与帕金森病相关的LRRK2的II型激酶抑制剂	Raig, N. D.	PDF	N/A	Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
Seipin调控了Caveolin-1的运输以及细胞器间的交流	Carpentier, M.	PDF	N/A	Seipin Regulates Caveolin-1 Trafficking and Organelle Crosstalk
甲醛在用于哺乳动物细胞培养时对信号通路的影响	Ostmann, K.	PDF	N/A	Influence of formaldehyde on signaling pathways when used in mammalian cell culture
A型和B型核纤层蛋白的详细共定位分析：使用超分辨率STED显微镜和去卷积的工作流程	Stiekema, M.	PDF	N/A	Detailed Colocalization Analysis of A- and B-type Nuclear Lamins: a Workflow Using Super-Resolution STED Microscopy and Deconvolution
溶酶体膜蛋白LAMP2B介导微脂质吞噬作用，以针对与肥胖相关疾病	Sakai, R.	PDF	N/A	The lysosomal membrane protein LAMP2B mediates microlipophagy to target obesity-related disorders
通过等离子体超表面实现活细胞的中红外化学成像	Huang, S. H.	PDF	N/A	Mid-infrared chemical imaging of living cells enabled by plasmonic metasurfaces
降低氧化应激改善了基于聚合物的体外人类造血干细胞和祖细胞培养及基因编辑	Bozhilov, Y.	PDF	N/A	Reducing oxidative stress improves ex vivo polymer-based human haematopoietic stem and progenitor cell culture and gene editing
后负荷诱导的脂肪酸氧化减少独立于葡萄糖利用增加而发展	Piristine, H.	PDF	N/A	Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization
解锁精准：角膜细胞面积分析如何革新移植后干细胞监测	Parkinson, P.	PDF	N/A	Unlocking precision: How corneal cell area analysis revolutionises post-transplant stem cell monitoring
体外评估挪威云杉（Picea abies）树脂提取物在口腔护理应用中的抗炎、抗牙菌斑功效及生物相容性	Yamileva, K.	PDF	N/A	In Vitro Evaluation of Anti-Inflammatory, Anti-Plaque Efficacy, and Biocompatibility of Norway Spruce (Picea abies) Resin Extract for Oral Care Applications
社会注意力取决于精确度的调节	Gao, W.	PDF	N/A	Precision-dependent modulation of social attention
采用SynthSeg框架和规范建模方法进行多发性硬化萎缩的纵向表征	Gordaliza, P. M.	PDF	N/A	Towards Longitudinal Characterization of Multiple Sclerosis Atrophy Employing SynthSeg Framework and Normative Modeling
CRISPR筛选用于rAAV生产的基因，揭示了与感染相关的基因	O'Driscoll, E.	PDF	N/A	CRISPR screen for rAAV production implicates genes associated with infection
每月对大型藻类的调查揭示了城市潮间带中一个多样且动态的生物群落。	Schenk, S.	PDF	N/A	Monthly macroalgal surveys reveal a diverse and dynamic community in an urban intertidal zone
针对未被关注的目标：揭示根系分泌物的化学复杂性	Moeller, K.	PDF	N/A	Targeting the untargeted: Uncovering the chemical complexity of root exudates
在孟德尔群体中，利他主义全同胞之间的生存成本分担	Garay, J.	PDF	N/A	Survival cost sharing among altruistic full siblings in Mendelian population
在大规模临床肺癌样本中筛选和鉴定基因表达，揭示了EZH2和SOX2的主要作用。	Niharika,	PDF	N/A	Screening and identification of gene expression in large cohorts of clinical lung cancer samples unveils the major involvement of EZH2 and SOX2
结核菌细胞壁阿拉伯聚糖末端阿拉伯糖基化的结构洞察	Liu, Y.	PDF	N/A	Structural insights into terminal arabinosylation biosynthesis of the mycobacterial cell wall arabinan
通过甘露糖基转移酶PimE研究分枝杆菌糖脂生物合成的机制	Liu, Y.	PDF	N/A	Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE
一种针对大蜡螟蛾（Galleria mellonella）的显微注射技术方案	Pearce, J. C.	PDF	N/A	A microinjection protocol for the greater waxworm moth, Galleria mellonella
可溶性细胞间通讯的工程受体	Piraner, D. I.	PDF	N/A	Engineered Receptors for Soluble Cell-to-Cell Communication
不同硬度聚丙烯酰胺（PAAm）水凝胶的合成及其在大批量细胞培养应用中的力学表征	Cresens, C.	PDF	N/A	Synthesis and mechanical characterization of polyacrylamide (PAAm) hydrogels with different stiffnesses for large-batch cell culture applications
UDG识别出双链DNA中翻转出来的尿嘧啶碱基的“那一刻”	Saravanan, V.	PDF	N/A	The "very moment" when UDG recognizes aflipped-out uracil base in dsDNA
基于网络的抗癌药物组合疗效和不良反应潜力评估，以优先排序	Ghosh, A.	PDF	N/A	Network-based estimation of therapeutic efficacy and adverse reaction potential for prioritisation of anti-cancer drug combinations
一种综合方法，用于提取经历液-液相分离的球状蛋白质的旋转动力学	Gendreizig, D.	PDF	N/A	A combined approach to extract rotational dynamics of globular proteins undergoing liquid-liquid phase separation
综合多组学方法揭示ZMAT3和p21在p53肿瘤抑制网络中作为保守枢纽的作用	Boutelle, A. M.	PDF	N/A	Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network
鉴定针对FGFR2融合驱动的胆管癌的高效双特异性抗体。	Chaturantabut, S.	PDF	N/A	Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma.
通过单细胞空间分析鉴定人肺组织中结核菌感染的SPP1阳性巨噬细胞	Katano, H.	PDF	N/A	Identification of SPP1-positive macrophages by single-cell spatial analysis in human lung tissues with mycobacterial infection
内皮miR-34a缺失虽导致内皮功能障碍，但能防止动脉瘤的发展。	Grochot-Przeczek, A.	PDF	N/A	Endothelial miR-34a deletion guards against aneurysm development despite endothelial dysfunction
胆固醇与VCAM-1结合促进血管炎症	Kennelly, J. P.	PDF	N/A	Cholesterol binding to VCAM-1 promotes vascular inflammation
灵长类主要组织相容性复合体：基因家族进化的一个典型例证	Fortier, A. L.	PDF	N/A	The Primate Major Histocompatibility Complex: An Illustrative Example of Gene Family Evolution
果蝇母体效应基因异常卵细胞（ao）并不抑制组蛋白基因的表达。	Takenaka, R.	PDF	N/A	The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression
一个驱动不可简化的分子复合物反复进化的调控模块。	Tikanova, P.	PDF	N/A	A regulatory module driving the recurrent evolution of irreducible molecular complexes.
犬基因组组装中核线粒体插入的特征分析	Schall, P. Z.	PDF	N/A	Characterization of nuclear mitochondrial insertions in canine genome assemblies
从单体到寡聚体：先天免疫信号传导中受体触发的MyD88组装的结构机制	Kasai, K.	PDF	N/A	From Monomers to Oligomers: Structural Mechanism of Receptor-Triggered MyD88 Assembly in Innate Immune Signaling
突变型p53错误折叠与聚集先于高级别浆液性卵巢癌的转化	Sartini, S.	PDF	N/A	Mutant p53 Misfolding and Aggregation Precedes Transformation into High-Grade Serous Ovarian Carcinoma
体外小鼠精准切割肿瘤切片用于肝细胞癌建模；一种适用于大规模药物筛选的3R解决方案	Collins, A. L.	PDF	N/A	Ex-vivo mouse precision cut tumour slices for modelling hepatocellular carcinoma; A 3Rs solution for at-scale drug screening
体外和体内评估海藻对伤口愈合的作用	Wang, C.-H.	PDF	N/A	In vitro and in vivo evaluation of Ulva lactuca for wound healing
在杂交小麦种子生产中，污点持久性并不是一个主要的限制因素。	Millan-Blanquez, M.	PDF	N/A	Stigma longevity is not a major limiting factor in hybrid wheat seed production
评估HIV-1包膜构象可塑性背景下的广谱中和抗体效能	Foulkes, C.	PDF	N/A	Assessing bnAb potency in the context of HIV-1 Envelope conformational plasticity
研究法洛四联症右心室血流动力学：一项计算研究	Renzi, F.	PDF	N/A	Investigating the right heart hemodynamics in the Tetralogy of Fallot: a computational study
PANOMIQ：一种统一的全基因组、外显子和微生物组数据分析方法	Srivastava, S.	PDF	N/A	PANOMIQ: A Unified Approach to Whole-Genome, Exome, and Microbiome Data Analysis
RCoxNet：结合随机游走重启与突变及临床数据的癌症生存预测深度学习框架	Kumari, S.	PDF	N/A	RCoxNet: deep learning framework for enhanced cancer survival prediction integrating random walk with restart with mutation and clinical data
协同药物发现中的主动学习指南	Wang, S.	PDF	N/A	A Guide for Active Learning in Synergistic Drug Discovery
FunCoup 6：通过引入有向链接和提升用户体验，推进跨物种功能关联网络的发展	Buzzao, D.	PDF	N/A	FunCoup 6: advancing functional association networks across species with directed links and improved user experience
环境和未减数配子的遗传结构如何影响同源多倍体的形成	Cheng, Y.	PDF	N/A	How environment and genetic architecture of unreduced gametes shape the establishment of autopolyploids
动物遗传变异致病性客观评估的变异分类指南	Boeykens, F.	PDF	N/A	Variant classification guidelines for animals to objectively evaluate genetic variant pathogenicity
侧前额叶皮层控制工作记忆与行动之间的相互作用。	Kiyonaga, A.	PDF	N/A	Lateral prefrontal cortex controls interplay between working memory and actions
急性病毒感染加速肌萎缩侧索硬化症小鼠模型中的神经退行性变	Marzok, A.	PDF	N/A	Acute Viral Infection Accelerates Neurodegeneration in a Mouse Model of ALS
蛋白质组学和N-糖基组学比较：合成与牛乳清蛋白及其对人类肠道微生物群的影响	Bolino, M.	PDF	N/A	Proteomic and N-glycomic comparison of synthetic and bovine whey proteins and their effect on human gut microbiomes
分子活性调节湖泊沉积物中溶解有机质的组成和组装	Wen, S.	PDF	N/A	Molecular activity mediates the composition and assembly of dissolved organic matter in lake sediments
胞质CRISPR RNA用于RNA靶向CRISPR-Cas系统	Kwon, S. C.	PDF	N/A	Cytosolic CRISPR RNA for RNA-targeting CRISPR-Cas systems
基于转录程序的MET外显子14跳跃调控网络解析	Truong, M.-J.	PDF	N/A	Transcriptional-program-based deciphering of the MET exon 14 skipping regulation network
Cas9AEY（Cas9辅助的非特异性大肠杆菌酵母载体同源重组组装）构建大型DNA的方法。	ma, x.	PDF	N/A	Cas9AEY (Cas9-facilitated Homologous Recombination Assembly of non-specific Escherichia coli yeast vector) method of constructing large-sized DNA.
肠道定居调节性T细胞（GTregs）的稳态平衡在维持绝经后骨质疏松症条件下的骨骼健康中起着关键作用。	Bhardwaj, A.	PDF	N/A	Homeostatic balance of Gut-resident Tregs (GTregs) plays a pivotal role in maintaining bone health under post-menopausal osteoporotic conditions
IL-27中和以调节肿瘤微环境并提高免疫检查点免疫治疗效果	Papargyris, L.	PDF	N/A	IL-27 neutralization to modulate the tumor microenvironment and increase immune checkpoint immunotherapy efficacy
NMI通过激活NF-kappaB通路诱导趋化因子释放并招募中性粒细胞。	Chen, Z.	PDF	N/A	NMI induces chemokine release and recruits neutrophils through the activation of NF-kappaB pathway
疟原虫物种的DNA复制动力学与基因组组成相关	Totanes, F. I. G.	PDF	N/A	DNA replication dynamics are associated with genome composition in Plasmodium species
一种从古代口腔微生物组创建宏基因组组装基因组的高效流程	Standeven, F. J.	PDF	N/A	An efficient pipeline for creating metagenomic-assembled genomes from ancient oral microbiomes
一种针对泛素调节的功能性筛选鉴定出由铜绿假单胞菌分泌的E3连接酶	Roberts, C. G.	PDF	N/A	A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa
系统基因组引导下发现古菌与细菌之间的拮抗相互作用	Strock, R.	PDF	N/A	Systematic genome-guided discovery of antagonistic interactions between archaea and bacteria
APEX2 细菌中RNA的邻近标记	Yassine, H.	PDF	N/A	APEX2 proximity labeling of RNA in bacteria
位于VIM-2活性位点附近的保守辅助残基影响其金属β-内酰胺酶活性。	Jain, D.	PDF	N/A	Conserved ancillary residues situated proximally to the VIM-2 active site affect its metallo β-lactamase activity
接种物大小对阿维巴坦-阿奇霉素组合在小鼠腹膜炎模型中体内活性的影响，该模型由表达CTX-M-15和NDM-1的大肠杆菌引起	Benchetrit, L.	PDF	N/A	Impact of the inoculum size on the in vivo activity of the aztreonam-avibactam combination in a murine model of peritonitis due to Escherichia coli expressing CTX-M-15 and NDM-1
微囊藻毒素通过社群过滤和影响交叉喂养互动来塑造微囊藻的藻圈。	Grosse, R.	PDF	N/A	Microcystin shapes the Microcystis phycosphere through community filtering and by influencing cross-feeding interactions
帽非依赖性翻译指导原生动物寄生虫刚地弓形虫应激诱导的分化	Dey, V.	PDF	N/A	Cap-independent translation directs stress-induced differentiation of the protozoan parasite Toxoplasma gondii
痤疮丙酸杆菌适应人类生活的特性提供了一种新的痤疮丙酸杆菌感染的生物标志物。	Shafiuddin, M.	PDF	N/A	Cutibacterium adaptation to life on humans provides a novel biomarker of C. acnes infections.
U2AF调控核编码线粒体mRNA的翻译和定位	Garcia, G. R.	PDF	N/A	U2AF regulates the translation and localization of nuclear-encoded mitochondrial mRNAs
核心剪接结构和早期剪接体识别决定了微外显子对SRRM3/4的敏感性	Bonnal, S.	PDF	N/A	Core splicing architecture and early spliceosomal recognition determine microexon sensitivity to SRRM3/4
利用面部侧面相似性改进人工智能驱动的海龟照片识别系统	Adam, L.	PDF	N/A	Exploiting facial side similarities to improve AI-driven sea turtle photo-identification systems
利用PiggyBac介导的转基因技术与CRISPR/Cas9敲除技术在大蜡螟（Galleria mellonella）中的应用	Pearce, J. C.	PDF	N/A	PiggyBac mediated transgenesis and CRISPR/Cas9 knockout in the greater waxmoth, Galleria mellonella
细胞衍生基质力学作为胶原蛋白VI相关先天性肌营养不良症的功能性读数	White, T.	PDF	N/A	Cell-derived matrices mechanics as a functional read-out in Collagen VI-related Congenital Muscular Dystrophies
喹啉协同作用与用量减少：一项药效动力学相互作用研究	Sadouki, Z.	PDF	N/A	Quinoline synergy and reduced use: a study of pharmacodynamic interactions
利用活体叶片切片成像技术分析C4植物叶肉细胞中依赖于维管束鞘细胞的叶绿体运动	Kato, Y.	PDF	N/A	Bundle sheath cell-dependent chloroplast movement in mesophyll cells of C4 plants analyzed using live leaf-section imaging
DNA模板空间控制蛋白水解靶向嵌合体用于CyclinD1-CDK4/6复合物蛋白降解	Zheng, R.	PDF	N/A	DNA-templated spatially controlled proteolysis targeting chimeras for CyclinD1-CDK4/6 complex protein degradation
来自结核分枝杆菌临床分离株的MHC I类/II类限制性T细胞表位：结核病疫苗开发的潜在候选者	Sharma, N.	PDF	N/A	MHC class I / II restricted T cell epitopes from clinical isolate of Mycobacterium tuberculosis: A potential candidate for vaccine development for Tuberculosis
光合作用由含有天线的视紫红质在浮游的Asgard古菌中进行	Tzlil, G.	PDF	N/A	Light-harvesting by antenna-containing rhodopsins in pelagic Asgard archaea
人巨细胞病毒vGPCR UL33对于上皮细胞中高效裂解复制至关重要	Freeman, M. R.	PDF	N/A	The Human Cytomegalovirus vGPCR UL33 is Essential for Efficient Lytic Replication in Epithelial Cells
通过多元素和锶同位素比率增强木材溯源性：来自东阿尔卑斯山的一个例子	Aguzzoni, A.	PDF	N/A	Enhancing timber traceability via multielement and strontium isotope ratio: An example from the Eastern Alps
metagWGS是一种综合工作流程，利用Illumina或PacBio HiFi读取数据来分析宏基因组数据。	Mainguy, J.	PDF	N/A	metagWGS, a comprehensive workflow to analyze metagenomic data using Illumina or PacBio HiFi reads
YTHDF1通过促进EEF1G翻译，以m6A依赖的方式促进肺腺癌进展	Wang, L.	PDF	N/A	YTHDF1 Facilitates Lung Adenocarcinoma Progression via Promotion of EEF1G Translation in a m6A-Dependent Manner
# BioRxiv 2024-09-17 Papers

标题	作者	PDF链接	代码仓库	Title
先前的脑电图标记了跨试验的专注和心智游移心理状态	Nakatani, C.	PDF	N/A	Prior EEG marks focused and mind-wandering mental states across trials
抑制ABCB7通过触发铁死亡增强顺铂在儿童3型髓母细胞瘤中的反应	Kanchan, R. K.	PDF	N/A	Repressing ABCB7 Potentiates Cisplatin Response in Pediatric Group 3 Medulloblastoma by Triggering Ferroptosis
灵长类动物主要组织相容性复合体中的古老跨物种多态性	Fortier, A. L.	PDF	N/A	Ancient Trans-Species Polymorphism at the Major Histocompatibility Complex in Primates
一种军团菌肺炎杆菌效应蛋白阻碍宿主基因沉默以促进毒力	Toinon, J.	PDF	N/A	A Legionella pneumophila effector impedes host gene silencing to promote virulence
基于细胞外基质的一个简单建模框架	Metzcar, J.	PDF	N/A	A simple framework for agent-based modeling with extracellular matrix
通过深度挖掘宏基因组基序来设计工程噬菌体	Huss, P.	PDF	N/A	Engineering bacteriophages through deep mining of metagenomic motifs
在生态学中追求新奇	Ottaviani, G.	PDF	N/A	On the quest for novelty in ecology
撤回：靶心与标准注视十字对眼球运动和从脑电图分类自然图像的影响	Häberle, G.	PDF	N/A	WITHDRAWN: The influence of the bullseye versus standard fixation cross on eye movements and classifying natural images from EEG
天冬酰胺的供应调控B细胞的体内平衡	Yazicioglu, Y. F.	PDF	N/A	Asparagine availability controls B cell homeostasis
拓扑异构酶3β在减轻细胞应激中的RNA靶点和功能	Teimuri, S.	PDF	N/A	RNA Targets and Function of Topoisomerase 3β in Reducing Cellular Stress
利用基于HHpred的方法对SARS-CoV-2蛋白进行重新注释，为更深入理解这种病毒开辟了新的途径。	Brezellec, P.	PDF	N/A	Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus
筛选人类可药物基因组确定ABHD17B为肝星状细胞中的抗纤维化靶点	Li, W.	PDF	N/A	Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
通过缝隙连接的细胞类型特异性核苷酸共享影响对复制应激的敏感性	Boumard, B.	PDF	N/A	Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress
与认知控制相关的大脑活动的寿命轨迹	Yang, G.	PDF	N/A	The Lifespan Trajectories of Brain Activities Related to Cognitive Control
CNTD1在女性减数分裂的I期进展和交叉点的指定中起着关键作用，对于建立卵巢储备至关重要。	Wood, A.	PDF	N/A	CNTD1 plays crucial roles in prophase I progression and crossover designation during female meiosis and is critical for establishing the ovarian reserve
神经生理学证据表明，感觉预测误差驱动了言语感觉运动适应。	Kim, K. S.	PDF	N/A	Neurophysiological evidence of sensory prediction errors driving speech sensorimotor adaptation
携带包膜的内源性逆转录病毒在后生动物中的前寒武纪起源	Chary, S.	PDF	N/A	Pre-Cambrian origin of envelope-carrying endogenous retroviruses in metazoans
前额叶皮层中不同的奖励线索表征导致了青少年和成年人在奖励动机上的差异	Manzano Nieves, G.	PDF	N/A	Divergent reward cue representations in prefrontal cortex underlie differences in reward motivation between adolescents and adults
脊髓V1抑制性中间神经元簇在出生日期、对运动神经元的投射以及异质性方面存在差异。	Worthy, A. E.	PDF	N/A	Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons and heterogeneity
金黄色葡萄球菌通过强大的丙氨酸消旋酶活性，抵御有机酸阴离子介导的肽聚糖交联抑制作用。	Panda, S.	PDF	N/A	Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity
任务无关的阶段，而非对比度变化，在视觉感知学习中解锁了泛化	Akkoyunlu, B.	PDF	N/A	Task-irrelevant phase but not contrast variability unlocks generalization in visual perceptual learning
从分子量分布的矩差推断代谢速率	Tuobang, L.	PDF	N/A	Infer metabolic velocities from moment differences of molecular weight distributions
HairSplitter：从长且有噪声的读取片段中组装单体型	Faure, R.	PDF	N/A	HairSplitter: haplotype assembly from long, noisy reads
在感知和工作记忆内容之间转移注意力的神经动力学	Gresch, D.	PDF	N/A	Neural dynamics of shifting attention between perception and working-memory contents
脑皮质神经元对脑震荡的转录反应揭示了损伤后的不同命运	Alkaslasi, M. R.	PDF	N/A	The transcriptional response of cortical neurons to concussion reveals divergent fates after injury
通过单核苷酸分辨率建模解析转录起始的核心启动子语法	He, A. Y.	PDF	N/A	Dissection of core promoter syntax through single nucleotide resolution modeling of transcription initiation
不同物种对四种细菌病原体易感性的系统发育信号变化	Sun, H.	PDF	N/A	Varying phylogenetic signal in susceptibility to four bacterial pathogens across species of Drosophilidae
二聚体-单体转变定义了一种超耐热肽聚糖水解酶，该酶通过源自溶菌素的抗菌肽引导筛选从细菌蛋白质组中挖掘得到。	Zhang, L.	PDF	N/A	Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening
预测疼痛基因：利用概率分类器和交互网络进行多模态数据整合	Zhao, N.	PDF	N/A	Predicting pain genes: multi-modal data integration using probabilistic classifiers and interaction networks
河口梯度下潮汐湿地土壤有机碳储量及其稳定机制	Neiske, F.	PDF	N/A	Soil organic carbon stocks and stabilization mechanisms in tidal marshes along estuarine gradients
使用独特标记基因集对scRNA-seq数据进行自动细胞注释	Truong, L.	PDF	N/A	Automated cell annotation in scRNA-seq data using unique marker gene sets
单细胞基因表达的综合分析：一种全面的数据库方法	Truong, L.	PDF	N/A	Integrative analysis of single-cell gene expression: A comprehensive database approach
一个用于简化序列分析的进化统计工具包，支持在网页上进行客户端处理	Karagöl, A.	PDF	N/A	An Evolutionary Statistics Toolkit for Simplified Sequence Analysis on Web with Client-Side Processing
在德国监测自由生活的蜜蜂群落：对栖息地偏好、存活率及公民科学可靠性的洞察	Rutschmann, B.	PDF	N/A	Monitoring free-living honeybee colonies in Germany: Insights into habitat preferences, survival rates, and Citizen Science reliability
睡眠-觉醒周期中突触稳态的边界条件	Kinoshita, F. L.	PDF	N/A	Boundary conditions for synaptic homeodynamics during the sleep-wake cycle
haCCA：空间转录组和代谢组的多模块整合。	Shen, X.	PDF	N/A	haCCA: Multi-module Integrating of spatial transcriptomes and metabolomes.
提高行为振荡检测的灵敏度：对Brookshire（2022）AR-替代方法的改进	Harris, A. M.	PDF	N/A	Detecting behavioural oscillations with increased sensitivity: A modification of Brookshire's (2022) AR-surrogate method
SQANTI-reads：一种用于多样本长读长RNA-seq实验中长读长数据质量评估的工具。	Keil, N.	PDF	N/A	SQANTI-reads: a tool for the quality assessment of long read data in multi-sample lrRNA-seq experiments.
训练对实验性发声学习缺乏经验的斑海豹进行发声学习实验	Duengen, D.	PDF	N/A	Training Experimentally Naive Seals for Vocal Learning Experiments
全基因组搜索鉴定可能赋予臭虫（Cimex lectularius）杀虫剂抗性的基因突变	Toga, K.	PDF	N/A	Genome-wide Search for Gene Mutations likely Conferring Insecticide Resistance in the Common Bed Bug, Cimex lectularius
鸭子接种高致病性禽流感疫苗的积极效果，法国2023-24年	Guinat, C.	PDF	N/A	Promising effects of duck vaccination against highly pathogenic avian influenza, France 2023-24
评估生理指标在利用对比问题测试（CQT）检测欺骗中的应用	Rashid, A. M. S.	PDF	N/A	Evaluating Physiological Indicators in Detecting Deception using the Comparison Question Test (CQT)
质子结合的变构调节使囊泡谷氨酸转运体具有Cl-激活和谷氨酸选择性	Borghans, B.	PDF	N/A	Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters
CRISPRoff表观遗传编辑技术：在人类细胞中实现可编程基因沉默，无需DNA断裂	Pattali, R. K.	PDF	N/A	CRISPRoff epigenetic editing for programmable gene silencing in human cells without DNA breaks
欧洲旧石器时代晚期气候变化下的人口反应	Schmidt, I.	PDF	N/A	Demographic responses to climatic changes during the Final Palaeolithic in Europe
参考样本的表观基因组、转录组和蛋白质组特征分析	Nepal, C.	PDF	N/A	Epigenomic, transcriptomic and proteomic characterizations of reference samples
注意力机制和状态空间基因组语言模型中标记化影响的比较	Lindsey, L. M.	PDF	N/A	A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models
SVbyEye：一种用于表征全基因组组装间结构变异的视觉工具	Porubsky, D.	PDF	N/A	SVbyEye: A visual tool to characterize structural variation among whole-genome assemblies
海洋酵母对基于昆布多糖的底物的利用和降解表明它们在微生物循环动力学中具有生态位特异性的作用。	Arslan-Gatz, B.	PDF	N/A	Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics.
连接组蛋白调控多能造血干细胞和祖细胞在髓系与淋巴系分化中的分支	Karatepe, K.	PDF	N/A	Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
朝着解释养殖北京鸭的繁殖差距迈进	Beyts, C. H.	PDF	N/A	Towards explaining the fertility gap in farmed Pekin ducks
全球树冠结构的谱系	Jucker, T.	PDF	N/A	The global spectrum of tree crown architecture
泛癌线粒体DNA修复基因集的遗传分析	Dong, A.	PDF	N/A	Pan-Cancer Genetic Analysis of Mitochondrial DNA Repair Gene Set
脊髓小脑性共济失调2型（SCA2）脑萎缩的模式与分期：来自ENIGMA-共济失调研究的MRI体积测量	Robertson, J. W.	PDF	N/A	The Pattern and Staging of Brain Atrophy in Spinocerebellar Ataxia Type 2 (SCA2): MRI Volumetrics from ENIGMA-Ataxia
蜱虫中一个单一的祖先ANP32位点产生了多种蛋白质变体，这些变体均支持Thogoto病毒聚合酶的功能。	Zhang, Z.	PDF	N/A	A single ancestral ANP32 locus in ticks creates multiple protein variants that all support the Thogoto virus polymerase
高通量优化的基于质粒编辑的内源性蛋白质标记技术，用于蛋白质定位的池化成像	Sanchez, H. M.	PDF	N/A	High-throughput optimized prime editing mediated endogenous protein tagging for pooled imaging of protein localization
使用蛋白质纳米笼在活细胞中定量比较单体StayGold变体	Viola, G.	PDF	N/A	Quantitative Comparison of Monomeric StayGold Variants Using Protein Nanocages in Living Cells
人诱导多能干细胞（iPSC）衍生的脑周细胞在炎症激活方面与原代人脑周细胞表现出差异。	McCullough, S.	PDF	N/A	Human iPSC-derived brain pericytes exhibit differences in inflammatory activation compared to primary human brain pericytes
自噬通过调控嘌呤核苷信号通路，起到抑制肥胖相关纤维化的作用。	Piletic, K.	PDF	N/A	Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling
HP1α驱动的相分离与异染色质损伤修复途径选择	Bohra, D.	PDF	N/A	HP1α-driven Phase Separation and Repair Pathway Choice in Response to Heterochromatin Damage
重新审视肠球菌属黄褐肠球菌及相关物种的分类	Soares de Medeiros Lima, M. M.	PDF	N/A	Revisiting the taxonomy of Enterococcus casseliflavus and related species
青络饮诱导的SIRT1抑制有助于佐剂诱导的关节炎大鼠免疫改善	Zuo, J.	PDF	N/A	Qing-Luo-Yin-induced SIRT1 inhibition contributes to the immune improvement of adjuvant-induced arthritis rats
更新了包含撤稿数据的科学领域标准化引用指标作者数据库	Ioannidis, J.	PDF	N/A	Updated science-wide author databases of standardized citation indicators including retraction data
H3K4me3结合的ALFIN-LIKE蛋白招募SWR1以在基因体内沉积H2A.Z	Xu, L.	PDF	N/A	The H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z
通过休眠的进化稳定波动的人口动态	Miller, Z. R.	PDF	N/A	Stabilization of fluctuating population dynamics via the evolution of dormancy
原发性口腔鳞状细胞癌的蛋白质基因组特征揭示了与淋巴结转移相关的细胞外基质重塑和免疫抑制微环境	Liu, Y.	PDF	N/A	Proteogenomic Characterization of Primary Oral Squamous Cell Carcinomas Unveils the Extracellular Matrix Remodeling and Immunosuppressive Microenvironment Linked with Lymph Node Metastasis
一种统一的贝叶斯方法用于转录组关联研究	Khan, A. K.	PDF	N/A	A unified Bayesian approach to transcriptome-wide association study
加速昆虫嗅觉受体配体的发现	Comte, A.	PDF	N/A	Accelerating Ligand Discovery for Insect Odorant Receptors
通过DeepFuseNMF实现空间转录组学数据的可解释高分辨率降维	Tang, J.	PDF	N/A	Interpretable high-resolution dimension reduction of spatial transcriptomics data by DeepFuseNMF
枝角类动物可保障替代急性鱼类毒性测试的生物检测方法的使用：重点关注神经毒性	Schuer, C.	PDF	N/A	Daphnids Can Safeguard the Use of Alternative Bioassays to the Acute Fish Toxicity Test: A Focus on Neurotoxicity
在加拿大引发高发播散性淋球菌感染的分离株中，表型多样性与共享的基因组决定因素	Binepal, G.	PDF	N/A	Phenotypic diversity and shared genomic determinants among isolates causing a large incidence of disseminated gonococcal infections in Canada
子宫肌层中PRICKLE1的缺失导致小鼠生育力下降、子宫肌层结构异常及细胞外基质沉积异常。	Roberts, E.	PDF	N/A	Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice.
在寒冷环境中发育使得鸟类线粒体更容易受到热应激的影响。	Correia, M.	PDF	N/A	Development in the cold renders bird mitochondria more susceptible to heat stress
在计算机探索中，Amubarvimab和Romlusevimab对SARS-COV-2变种的中和机制	Huan, X.	PDF	N/A	In computer explore The neutralization mechanism of Amubarvimab and Romlusevimab against SARS-COV-2 mutants
一种主要真菌病原体在全球收集物中的热适应性	Minana-Posada, S.	PDF	N/A	Thermal adaptation in worldwide collections of a major fungal pathogen
p53通过调节核结构来降低致癌物敏感性和突变潜能	King, D. A.	PDF	N/A	p53 Regulates Nuclear Architecture to Reduce Carcinogen Sensitivity and Mutagenic Potential
针对癌症相关糖基化进行胃肠道和妇科癌症的过继T细胞治疗	Zingg, A.	PDF	N/A	Targeting cancer-associated glycosylation for adoptive T cell therapy of gastro-intestinal and gynecological cancers
抑制谷氨酰胺酶可诱导治疗诱导的衰老黑色素瘤细胞的衰老消解。	Kim, J.	PDF	N/A	Inhibition of glutaminase elicits senolysis in therapy-induced senescent melanoma cells.
在Pristionchus中，发育转录组学揭示了可塑性基因调控网络的逻辑	Reich, S.	PDF	N/A	Developmental transcriptomics in Pristionchus reveals the logic of a plasticity gene regulatory network
纹状体中快速放电中间神经元的功能性后果	Guo, L.	PDF	N/A	Functional consequences of fast-spiking interneurons in striatum
一种结合了树突非线性特性和反向传播动作电位的V1神经模型	Rentzeperis, I.	PDF	N/A	A neural model for V1 that incorporates dendritic nonlinearities and back-propagating action potentials
层流功能定量磁化率成像的可行性	Straub, S.	PDF	N/A	Feasibility of laminar functional quantitative susceptibility mapping
全脑微卒中影响海马记忆回路的稳定性	Heiser, H.	PDF	N/A	Brain-wide microstrokes affect the stability of memory circuits in the hippocampus
使用条件性GeneSwitch驱动器扩展果蝇血细胞会影响幼虫血细胞功能，但不会调节成虫的寿命或感染后的存活率。	Hayman, D. J.	PDF	N/A	Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival from infection
倾斜错觉源于在上下文边界处对神经编码资源的高效重新分配。	Zhang, L.-Q.	PDF	N/A	The tilt illusion arises from an efficient reallocation of neural coding resources at the contextual boundary
通过眶额皮层自上而下的输入对感觉反应进行预测性过滤	Tsukano, H.	PDF	N/A	Predictive filtering of sensory response via orbitofrontal top-down input
通过解剖和显微计算机断层扫描识别出的人类三叉神经和面神经分支及孔道的变异	Grimes, H. L.	PDF	N/A	Variations in human trigeminal and facial nerve branches and foramina identified by dissection and microcomputed tomography
海马体中人口活动的稀疏性在三突触回路和背腹轴上是任务不变的。	Lee, J. Q.	PDF	N/A	Sparsity of population activity in the hippocampus is task-invariant across the tri-synaptic circuit and dorsal-ventral axis
从前馈到反馈节奏的表征转变，标志着自然视觉中现象学整合的指标。	Chen, L.	PDF	N/A	Representational shifts from feedforward to feedback rhythms index phenomenological integration in natural vision
单极刷状细胞接收到的真实苔藓纤维输入模式，能够引发一系列时间响应，这些响应由不同谷氨酸受体介导的成分组成。	Huson, V.	PDF	N/A	Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors
行为控制的神经递质基础	Ballard, I. C.	PDF	N/A	A dopaminergic basis of behavioral control
皮质连接支持运动同步，以响应前额叶-颞叶网络中的听觉和视觉节奏。	Lu, Y.	PDF	N/A	Cortical connectivity supports motoric synchronization to both auditory and visual rhythms in a frontal-temporal network
清醒大鼠内脏操作的神经影像学模型	Cramer, S. R.	PDF	N/A	Neuroimaging model of visceral manipulation in awake rat
胎儿期暴露于四氢大麻酚（THC）后，急性应激的性别特异性适应不良反应受多巴胺介导。	Serra, V.	PDF	N/A	Sex-specific maladaptive responses to acute stress upon in utero THC exposure are mediated by dopamine
基于MRI的阿尔茨海默病分类的可解释AI模型比较	Chattopadhyay, T.	PDF	N/A	Comparison of Explainable AI Models for MRI-based Alzheimer's Disease Classification
背侧中缝核中的GABA能神经元调节小鼠的社会等级	Fang, G.	PDF	N/A	GABAergic neurons in the dorsal raphe nucleus regulate social hierarchy in mice
杏仁核刺激通过前扣带皮层中非典型PKC的持续激活，将短期记忆转化为远程记忆。	Almaguer-Melian, W.	PDF	N/A	Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical PKC in the anterior cingulate cortex
尽管关键标记基因发生了显著变化，颗粒性后海马皮质的独特转录组细胞类型在鼠和鼠之间得以保留	Brooks, I. A.	PDF	N/A	Unique Transcriptomic Cell Types of the Granular Retrosplenial Cortex are Preserved Across Mice and Rats Despite Dramatic Changes in Key Marker Genes
星形胶质细胞糖皮质激素受体介导应激后性特异性活动变化	Depaauw-Holt, L.	PDF	N/A	Astrocyte glucocorticoid receptors mediate sex-specific changes in activity following stress
高分辨率活体运动学追踪与可注射荧光纳米颗粒	Ulutas, E. Z.	PDF	N/A	High-resolution in vivo kinematic tracking with injectable fluorescent nanoparticles
在小鼠齿状回中，5-HT7受体的激活选择性地增强了GABA能抑制作用，这种抑制作用针对的是门区的苔藓细胞，而不会影响穿通路径突触的可塑性。	Siwiec, M.	PDF	N/A	Activation of 5-HT7 receptors in the mouse dentate gyrus selectively enhances GABAergic inhibition of hilar mossy cells without affecting plasticity at the perforant path synapse
神经元中内源性大麻素过多对认知功能有害。	Zhu, D.	PDF	N/A	Overabundant endocannabinoids in neurons are detrimental to cognitive function
Notch/无毛通路对原肠胚形成前sog转录爆发的调控	Fenelon, K. D.	PDF	N/A	Notch/Hairless Pathway Modulation of sog Transcriptional Bursting in Prelude to Gastrulation
单细胞多组学、空间转录组学和系统扰动揭示神经嵴命运决定的电路	Hu, Z.	PDF	N/A	Single-cell multi-omics, spatial transcriptomics and systematic perturbation decode circuitry of neural crest fate decisions
肉类转移遵循几内亚狒狒多层次社会中的社会关系，但与雄性繁殖成功无关。	O'Hearn, W. J.	PDF	N/A	Meat transfers follow social ties in the multi-level society of Guinea baboons but are not related to male reproductive success
跳蛛不会被周边漂移错觉所迷惑	De Agro, M.	PDF	N/A	Jumping spiders are not fooled by the peripheral drift illusion
温暖水域中猎物显著性的增强缓解了浊度对捕食者的视觉限制	Zanghi, C.	PDF	N/A	Enhanced conspicuousness of prey in warmer water mitigates the visual constraint of turbidity for predators
注意缺陷多动障碍儿童和青少年的大脑边缘系统白质：一项纵向扩散磁共振成像分析	Connaughton, M.	PDF	N/A	Limbic System White Matter in Children and Adolescents with ADHD: A Longitudinal Diffusion MRI Analysis
阿尔茨海默病的病理学破坏了在小鼠进行风险觅食决策期间，灵活的位置细胞编码和海马-前额叶神经动力学。	Kim, E. J.	PDF	N/A	Alzheimer's pathology disrupts flexible place cell coding and hippocampal-prefrontal neural dynamics during risky foraging decisions in mice
皮层状态对早期视觉皮层反应变异性的贡献：一种系统识别方法	Sooriyaarachchi, J.	PDF	N/A	Cortical state contributions to response variability in the early visual cortex: A system identification approach
面部表情与颜色在调节EPR P3中的相互作用	Hasegawa, Y.	PDF	N/A	Interaction between facial expression and color in modulating EPR P3
MPXV以I型干扰素敏感的方式感染人外周血单核细胞	Bosquillon de Jarcy, L.	PDF	N/A	MPXV Infects Human PBMCs in a Type I Interferon-Sensitive Manner
SARS-Cov-2 N蛋白的亲和标签免费纯化及其与ssDNA复合物的晶体结构	Maiti, A.	PDF	N/A	Affinity tag free purification of SARS-Cov-2 N protein and its crystal structure in complex with ssDNA
PangeBlocks：通过最大块实现泛基因组图的自定义构建	Bonizzoni, P.	PDF	N/A	PangeBlocks: customized construction of pangenome graphs via maximal blocks
基于相分离合成细胞器的代谢物响应转录调控	Jerez-Longres, C.	PDF	N/A	Metabolite-responsive Control of Transcription by Phase Separation-based Synthetic Organelles
一种用于编程干细胞内源基因多步骤激活的模块化系统	Puppala, A. K.	PDF	N/A	A modular system for programming multistep activation of endogenous genes in stem cells
在聚球藻PCC 7002中实现高效转化与基因表达	Hren, A. P.	PDF	N/A	High-efficiency transformation and gene expression in Picosynechococcus sp. PCC 7002
合成细胞模型中膜相分离与细菌分裂蛋白动态之间的相互依赖关系	Kanwa, N.	PDF	N/A	Mutual dependence between membrane phase separation and bacterial division protein dynamics in synthetic cell models
炎症和转移性癌症中肺淋巴管的原位成像	Cleary, S. J.	PDF	N/A	Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer
一个涵盖5000年的古代人类口腔微生物组研究的广泛考古牙结石数据集	Standeven, F. J.	PDF	N/A	An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research
斯里兰卡人感染的细螺旋体博氏菌株的基因组分析揭示了PF07598基因家族谱系的扩展，其整体基因组缩减程度低于牛感染的菌株。	Senavirathna, I.	PDF	N/A	Genomic Analysis of Human-infecting Leptospira borgpetersenii isolates in Sri Lanka expanded PF07598 gene family repertoire, less overall genome reduction than bovine isolates
一种慢性小鼠肺部鲍曼不动杆菌感染模型，可用于研究晚期毒力因子、长期抗生素治疗以及多菌种感染。	Jackson-Litteken, C. D. D.	PDF	N/A	A chronic murine model of pulmonary Acinetobacter baumannii infection enabling the investigation of late virulence factors, long-term antibiotic treatments, and polymicrobial infections
人类肠道细菌对PFAS的广泛积累	Lindell, A. E.	PDF	N/A	Extensive PFAS accumulation by human gut bacteria
艰难梭菌的ruberythrin基因座能有效解毒活性氧物质。	Knop, R.	PDF	N/A	A rubrerythrin locus of Clostridioides difficile efficiently detoxifies reactive oxygen species
标题：坦桑尼亚北部野生动物保护区附近牛群非洲动物锥虫病治疗失败原因的纵向观察（单队列）研究	Richards, S.	PDF	N/A	Title Longitudinal Observational (single cohort) Study on the Causes of Trypanocide Failure in cases of African Animal Trypanosomosis in Cattle Near Wildlife Protected Areas of Northern Tanzania
RNA聚合酶II在活性启动子上协调组蛋白去乙酰化	Hoffman, J. A.	PDF	N/A	RNA Polymerase II coordinates histone deacetylation at active promoters
Transportin-1介导的PPARg核运输机制的结构解析	TOMA-FUKAI, S.	PDF	N/A	Structural insight into the nuclear transportation mechanism of PPARg by Transportin-1
针对FUS-ALS聚集，使用蛋白酶体抑制剂进行靶向治疗	Younis, A.	PDF	N/A	Targeting FUS-ALS aggregation with Proteasome Inhibitors
通过激活mTOR/TFEB增强溶酶体功能可减少早期年龄相关性黄斑变性中的脂褐素样颗粒	Falcao, A. S.	PDF	N/A	Enhancing lysosome function via mTOR/TFEB activation reduces lipofuscin-like granules in early Age-related Macular Degeneration
pytom-match-pick：模板匹配中用于自动化分类的tophat-transform约束	Chaillet, M. L.	PDF	N/A	pytom-match-pick: a tophat-transform constraint for automated classification in template matching
评估埃博拉病毒在刚果民主共和国赤道省的传播：一项关于野生动物与人类互动的一体化健康调查	van Vredendaal, R.	PDF	N/A	Assessing Ebola Virus Circulation in the Tshuapa Province (Democratic Republic of the Congo): A One Health Investigation of Wildlife and Human Interactions
将种内变异整合到种群动态中，揭示了相互作用的物种如何在互利共生群落中持续存在	Arroyo-Correa, B.	PDF	N/A	Integrating intraspecific variation into population dynamics reveals how interacting species persist in mutualistic communities
气候适应性有助于全球入侵	Gamba, D.	PDF	N/A	Local adaptation to climate facilitates a global invasion
过去5000年葡萄牙的遗传史	Roca-Rada, X.	PDF	N/A	The genetic history of Portugal over the past 5,000 years
利用直接胶原纤维模型捕捉巩膜各向异性。将微观结构与宏观力学特性联系起来。	Ji, F.	PDF	N/A	Capturing sclera anisotropy using direct collagen fiber models. Linking microstructure to macroscopic mechanical properties.
使用可调细胞外基质水凝胶系统精准修复特定区域的半月板损伤	Lee, S.-H.	PDF	N/A	Precision Repair of Zone-Specific Meniscal Injuries Using a Tunable Extracellular Matrix-Based Hydrogel System
CRAK-Velo：染色质可及性动力学整合提升RNA速度估算	El Kazwini, N.	PDF	N/A	CRAK-Velo: Chromatin Accessibility Kinetics integration improves RNA Velocity estimation
短读长纳米孔测序的精确碱基识别	Wang, Z.	PDF	N/A	The Precise Basecalling of Short-Read Nanopore Sequencing
尽管存档切片存在噪声，机器学习仍能收敛于黑色素细胞形态	Tada, M.	PDF	N/A	Machine-learning convergent melanocytic morphology despite noisy archival slides
连接小管中的通路流动引起传入小动脉的血管舒张。	Wang, H.	PDF	N/A	Luminal Flow in the Connecting Tubule induces Afferent Arteriole Vasodilation
利用分裂mVenus方法在植物系统中实施Ribo-BiFC技术的实现	Raabe, K.	PDF	N/A	Implementation of Ribo-BiFC method to plant systems using a split mVenus approach
在鼠伤寒沙门氏菌中可逆地切除wzy位点可能有助于在噬菌体捕食后恢复	Charity, O. J.	PDF	N/A	Reversible excision of the wzy locus in Salmonella Typhimurium may aid recovery following phage predation
利用工程化的连接选择性去泛素化酶解码多泛素化对KV7.1功能表达的调控	Shanmugam, S. K.	PDF	N/A	Decoding polyubiquitin regulation of KV7. 1 functional expression with engineered linkage-selective deubiquitinases
利用高分辨率基因表达谱揭示被子植物中全基因组加倍后的保守进化响应	Leal, J. L.	PDF	N/A	Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling
人类凝聚蛋白亚基的分子动力学模拟识别出DNA结合位点及其在DNA环挤出中的潜在作用	Gu, C.	PDF	N/A	Molecular dynamics simulations of human cohesin subunits identify DNA binding sites and their potential roles in DNA loop extrusion
# BioRxiv 2024-09-16 Papers

标题	作者	PDF链接	代码仓库	Title
Tasselyzer是一种基于PlantCV的机器学习方法，用于量化玉米花药的伸展情况。	Teng, C.	PDF	N/A	Tasselyzer, a machine learning method to quantify maize anther exertion, based on PlantCV
3'UTR介导的、激酶近端的mRNA降解通过抑制C/EBPβ的磷酸化/激活来抑制肿瘤细胞的衰老	Salotti, J.	PDF	N/A	3'UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells
线粒体铁通过MFRN1的转运对于红细胞周期的进展是必需的。	Perfetto, M.	PDF	N/A	Mitochondrial iron transport via MFRN1 is required for erythroid cell cycle progression
单粒子追踪揭示了PIEZO1扩散的异质性	Ly, A. T.	PDF	N/A	Single-particle tracking reveals heterogeneous PIEZO1 diffusion
水模型对酶通道结构和动力学的影响	Agrawal, N.	PDF	N/A	Impact of water models on structure and dynamics of enzyme tunnels
快速分类与对伤害意图的精细学习：血清素与种族偏见的作用	Moutoussis, M.	PDF	N/A	Rapid classification vs. refined learning about harm intent: Roles of serotonin and racial bias
不同的大脑皮层突触前网络构成了单个皮层神经元的功能特性。	Inacio, A. R.	PDF	N/A	Distinct brain-wide presynaptic networks underlie the functional identity of individual cortical neurons
血餐来源和季节性对尖音库蚊（双翅目：蚊科）繁殖特性的影响	Rucci, K. A.	PDF	N/A	Effects of blood meal source and seasonality on reproductive traits of Culex quinquefasciatus (Diptera: Culicidae)
与日本脑炎病毒相关的景观反映了澳大利亚和中印度-太平洋地区水鸟物种的功能生物地理学。	Walsh, M.	PDF	N/A	Landscapes associated with Japanese encephalitis virus reflect the functional biogeography of waterbird species across Australia and the Central Indo-Pacific region
SACNet：一种具有先验神经解剖学约束的多尺度微分同胚卷积配准网络，用于回波平面成像中的灵活磁敏感伪影校正	Zeng, Z.	PDF	N/A	SACNet: A Multiscale Diffeomorphic Convolutional Registration Network with Prior Neuroanatomical Constraints for Flexible Susceptibility Artifact Correction in Echo Planar Imaging
全细胞多目标单分子超分辨率三维成像与微流控技术和单物镜倾斜光片	Gagliano, G.	PDF	N/A	Whole-cell multi-target single-molecule super resolution imaging in 3D with microfluidics and a single-objective tilted light sheet
打开物种箱：微观简约的物种形成模型对宏观进化的启示	Couvert, E.	PDF	N/A	Opening the species box: What microscopic parsimonious models of speciation have to say about macroevolution
肠道微生物群相关的长链脂肪酸硬脂酸抑制结直肠癌	Tsenkova, M.	PDF	N/A	The gut microbiome-linked long chain fatty acid stearate suppresses colorectal cancer
在整个皮层中，对于自信预测的视觉输入的能量节省	Hechler, A.	PDF	N/A	Energy savings across the cortex for confidently predicted visual input
肌成纤维细胞增殖受损是病理性产后肺泡简化的核心特征	Khan, I. S.	PDF	N/A	Impaired Myofibroblast Proliferation is a Central Feature of Pathologic Post-Natal Alveolar Simplification
神经动力学与癫痫发作相关性：破伤风毒素大鼠癫痫模型中神经质量模型的见解	Zarei Eskikand, P.	PDF	N/A	Neural Dynamics and Seizure Correlations: Insights from Neural Mass Models in a Tetanus Toxin Rat Model of Epilepsy
MagIC-Cryo-EM：在异质样本中对稀缺大分子进行磁珠结构测定	Arimura, Y.	PDF	N/A	MagIC-Cryo-EM: Structural determination on magnetic beads for scarce macromolecules in heterogeneous samples
NeuroCSF：一种用于测量人类视觉皮层对比敏感度函数的fMRI方法	Goulet, L. L.	PDF	N/A	NeuroCSF: an fMRI method to measure contrast sensitivity function in human visual cortex
ARX多聚丙氨酸突变在人类皮层和中间神经元发育中的双重效应	Nieto-Estevez, V.	PDF	N/A	Dual effects of ARX poly-alanine mutations in human cortical and interneuron development
一种转录网络是线粒体生物发生双重基因组协调的基础	Xu, H.	PDF	N/A	A transcription network underlies the dual genomic coordination of mitochondrial biogenesis
整合的WF-哈丁（WFH）模型解决了分子进化中的许多悖论	Ruan, Y.	PDF	N/A	The integrated WF-Haldane (WFH) model of genetic drift resolving the many paradoxes of molecular evolution
新型基因编码探针用于通过偏振显微镜对细胞信号传导的功能成像	Miclea, P. S.	PDF	N/A	Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy
耐盐黑酵母Hortaea werneckii的异位DNA整合与无标记CRISPR/Cas9策略	Hernandez-Rodriguez, Y.	PDF	N/A	Ectopic DNA integration and marker-free CRISPR/Cas9 strategies for the halotolerant black yeast Hortaea werneckii
PDGFRα信号调控Srsf3转录本结合，影响PI3K信号传导和内体运输	Forman, T. E.	PDF	N/A	PDGFRα signaling regulates Srsf3 transcript binding to affect PI3K signaling and endosomal trafficking
RNA语言模型预测能够增强RNA功能的突变	Shulgina, Y.	PDF	N/A	RNA language models predict mutations that improve RNA function
心脏分化路线图用于分析可塑性和平衡的谱系承诺	Snabel, R. R.	PDF	N/A	Cardiac differentiation roadmap for analysis of plasticity and balanced lineage commitment
针对现实世界任务优化的模型揭示了听觉中任务依赖性精确时间编码的必要性。	Saddler, M. R.	PDF	N/A	Models optimized for real-world tasks reveal the task-dependent necessity of precise temporal coding in hearing
松树、杰克松及其杂交种对真菌病原体松树小蠹菌的遗传结构响应	Lu, M.	PDF	N/A	Genetic architecture underlying response to the fungal pathogen Dothistroma septosporum in lodgepole pine, jack pine, and their hybrids
1型糖尿病发病前后人类胰腺淋巴组织中的免疫扰动	Golden, G. J.	PDF	N/A	Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset
在单层和双层中的脂质扩散动力学的比较，涉及脂质层间耦合的背景。	Mandal, T.	PDF	N/A	A comparison of lipid diffusive dynamics in monolayers and bilayers in the context of interleaflet coupling
社会复杂性对白蚁中自然选择效力的影响	Roux, C.	PDF	N/A	The impact of social complexity on the efficacy of natural selection in termites
细胞分化调控领鞭毛虫铁吸收	Leon, F.	PDF	N/A	Cell differentiation controls iron assimilation in a choanoflagellate
GLARE：利用表示学习揭示太空飞行转录组中的隐藏模式	Seo, D.	PDF	N/A	GLARE: Discovering Hidden Patterns in Spaceflight Transcriptome Using Representation Learning
带有不平地形的分带式测力跑步机	Kuo, A. D.	PDF	N/A	A split-belt instrumented treadmill with uneven terrain
多元化的全球植物油生产能够缓解气候变化，并实现社会与环境的共同效益。	Zeng, S.	PDF	N/A	Diversified global vegetable oil production can mitigate climate change and achieve socio-environmental co-benefits
肠道血清素迷走神经信号作为微生物群诱发高血压的中介因素	de Araujo, A.	PDF	N/A	Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension
值班爸爸：疣鼻栖鸭孵蛋首记录	Scheiber, I. B. R.	PDF	N/A	Dads on duty: First account of nest sitting in barnacle ganders
绿色植物的染色体数目与生殖生命周期：一个系统发生-转录组学的视角	Dhakal, R.	PDF	N/A	Chromosome Numbers and Reproductive Life Cycles in Green Plants: A phylo-transcriptomic perspective
在欧洲恢复的湿地生态系统中，野化马和牛的栖息地利用与植物群落的功能和结构组成相关	Lovasz, L.	PDF	N/A	Habitat use of rewilded horses and cattle as related to the functional and structural composition of plant communities in a European restored wetland ecosystem
SMURF1/2是WNK1稳定性的新型调控因子	Jaykumar, A. B.	PDF	N/A	SMURF1/2 are novel regulators of WNK1 stability
通过计算重建实现可扩展的无图像空间基因组学	Hu, C.	PDF	N/A	Scalable imaging-free spatial genomics through computational reconstruction
谱系限制的机制基础	Wu, B.	PDF	N/A	Mechanistic basis of lineage restriction
天堂鱼（Macropodus opercularis）作为情感和认知功能的新型转化模型	Varga, Z. K.	PDF	N/A	Paradise fish (Macropodus opercularis) as novel translational model for emotional and cognitive function
单分子脂质生物传感器减轻内源性效应蛋白的抑制作用	Holmes, V.	PDF	N/A	Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins
单分子脂质生物传感器减轻内源性效应蛋白的抑制	Holmes, V.	PDF	N/A	Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins
细菌基因组编码的ParM	Ali, S.	PDF	N/A	Bacterial genome encoded ParMs
鉴定出一种调节免疫反应的真菌抗菌内肽酶	Machata, S.	PDF	N/A	Identification of a fungal antibacterial endopeptidase that modulates immune responses
应激诱导小蛋白的翻译谱分析揭示了不同信号系统之间意想不到的联系	Vellappan, S.	PDF	N/A	Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems
元意识、心智游移以及对“默认”外部和内部注意定向的控制	Christian, I. R.	PDF	N/A	Meta-awareness, mind-wandering, and the control of 'default' external and internal orientations of attention
当小龙虾成为新闻时，标题虽然正确，但仍具误导性。	Faulkes, Z.	PDF	N/A	When crayfish make news, headlines are correct but still misleading
easybio：一个用于使用CellMarker2.0进行单细胞注释的R包	Wei, C.	PDF	N/A	easybio: an R Package for Single-Cell Annotation with CellMarker2.0
机械负荷和激素变化对容量超负荷期间离心肥大的贡献：基于逻辑网络模型的贝叶斯分析。	Bracamonte, J. H.	PDF	N/A	Contributions of mechanical loading and hormonal changes to eccentric hypertrophy during volume overload: a Bayesian analysis using logic-based network models.
一种结构MRI标记物预测了个体在冲动性方面的差异，并将行为变异型额颞叶痴呆患者与匹配的对照组进行了分类。	Godefroy, V.	PDF	N/A	A structural MRI marker predicts individual differences in impulsivity and classifies patients with behavioral-variant frontotemporal dementia from matched controls
XbnAb 群体：304 名对 HIV-1 具有广泛中和抗体活性的人	Pasin, C.	PDF	N/A	The XbnAb Cohort: 304 people with broadly neutralizing antibody activity to HIV-1
Bcl-xL缺陷的MDCK细胞中肿瘤发生能力降低，确保了流感疫苗生产的安全性。	Zheng, J.	PDF	N/A	Tumorigencity decrease in Bcl-xL deficient MDCK cells ensuring the safety for influenza vaccine production
复杂群体形态发育过程中基因表达的时空模式	Cromie, G. A.	PDF	N/A	Spatiotemporal Patterns of Gene Expression During Development of a Complex Colony Morphology
rDNA阵列的表观遗传调控与遗传	Potapova, T. A.	PDF	N/A	Epigenetic control and inheritance of rDNA arrays
gsQTL：通过利用其共享变异性将遗传风险变异与基因集相关联	Bouland, G. A.	PDF	N/A	gsQTL: Associating genetic risk variants with gene sets by exploiting their shared variability
线虫基因组中的调控逻辑与转座元件动态	Fierst, J. L.	PDF	N/A	Regulatory logic and transposable element dynamics in nematode worm genomes
基于社区的病媒传播疾病昆虫学监测与控制：范围综述	Eastman, P.	PDF	N/A	Community-Based Entomological Surveillance and Control of Vector-Borne Diseases: A Scoping Review
熟悉的人和地方在类别选择性皮层的视觉影像	Scrivener, C. L.	PDF	N/A	Visual imagery of familiar people and places in category selective cortex
跨诊断症状领域与儿童多模态成像期间头部运动相关	Hercules, K.	PDF	N/A	Transdiagnostic Symptom Domains are Associated with Head Motion During Multimodal Imaging in Children
使用重组脱氧核糖核酸酶I治疗抗髓过氧化物酶性肾小球肾炎，通过腺相关病毒基因疗法得到增强	Cao Le, A.	PDF	N/A	Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy
在人类星状病毒衣壳刺突上发现三个新的中和抗体表位，并揭示病毒中和的机制性见解	Lanning, S.	PDF	N/A	Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization
晚发性阿尔茨海默病风险因子iRhom2/RHBDF2是微胶质细胞TREM2蛋白水解的修饰因子	Jocher, G.	PDF	N/A	The late onset Alzheimer's disease risk factor iRhom2/RHBDF2 is a modifier of microglial TREM2 proteolysis
MLPA：一种用于个性化癌症模拟和治疗优化的多尺度数字孪生框架	Chen, J. Y.	PDF	N/A	MLPA: A Multi-scale Digital Twin Framework for Personalized Cancer Simulation and Treatment Optimization
间充质干细胞衍生的细胞外囊泡可缓解咪喹莫特诱导的小鼠疾病模型中的银屑病症状	Yi, Y.	PDF	N/A	Mesenchymal stem cell-derived extracellular vesicles alleviate imiquimod-induced psoriasis symptoms in a mouse disease model
对制药行业和研究密集型学术机构的开放获取出版率进行基准测试	Rees, T. J.	PDF	N/A	Benchmarking open access publication rates for the pharmaceutical industry and research-intensive academic institutions
鸟类命名马拉松：利用众包对英语鸟类名称进行分类	Morrison, E. S.	PDF	N/A	Bird Name-a-thon: Categorizing English bird names using crowdsourcing
TRPV3通道活性有助于皮层神经元在发热期间保持活跃。	Shen, Y.	PDF	N/A	TRPV3 channel activity helps cortical neurons stay active during fever
文化定向广告牌信息的注意力和保持效果：使用沉浸式虚拟现实的眼动追踪研究	Jeon, M.	PDF	N/A	Attention and Retention Effects of Culturally Targeted Billboard Messages: An Eye-Tracking Study Using Immersive Virtual Reality
转录组学和多尺度网络分析揭示了心血管疾病的关键驱动因素	Tumenbayar, B.-I.	PDF	N/A	Transcriptomic and multi-scale network analyses reveal key drivers of cardiovascular disease
深度学习直接从序列预测非正常肽的FAIMS迁移率分布	McKetney, J.	PDF	N/A	Deep Learning Predicts Non-Normal Peptide FAIMS Mobility Distributions Directly from Sequence
SPL家族转录因子DNA结合特异性的多样化和保守性	Li, M.	PDF	N/A	Diversification and conservation of DNA binding specificities of SPL family of transcription factors
高内涵显微镜与机器学习相结合，揭示了施万细胞中NF1基因型特有的细胞形态特征。	Tomkinson, J.	PDF	N/A	High-content microscopy and machine learning characterize a cell morphology signature of NF1 genotype in Schwann cells
组织特异性代谢组特征用于减少性二态性的doublesex模型	Coig, R.	PDF	N/A	Tissue-specific metabolomic signatures for a doublesex model of reduced sexual dimorphism
寨卡病毒NS3驱动形成类似病毒体的结构	Sultana, T.	PDF	N/A	Zika virus NS3 drives the assembly of a viroplasm-like structure
一种结合纳米纤维和间充质细胞球体的混合生物打印-静电纺丝平台，用于定制化伤口愈合敷料。	Hosseini, S. A.	PDF	N/A	A hybrid bioprinting-electrospinning platform integrating nanofibers and mesenchymal cell spheroids for customizable wound healing dressings
肌醇六磷酸（InsP6）通过激活HDAC1/3表观遗传轴来维持肠道屏障功能	Chatterjee, S.	PDF	N/A	Inositol Hexaphosphate (InsP6) Activates the HDAC1/3 Epigenetic Axis toMaintain Intestinal Barrier Function
依赖于细胞周期的S-亚磺酰基蛋白质组学揭示了p21-CDK反馈中的氧化还原开关，该开关调控增殖-衰老决策	Vorhauser, J.	PDF	N/A	Cell cycle-dependent S-sulfenyl proteomics uncover a redox switch in p21-CDK feedback governing the proliferation-senescence decision
细胞外凝聚物（ECs）是HIV转录和潜伏再激活的内源性调节因子。	Naushad, W.	PDF	N/A	Extracellular condensates (ECs) are endogenous modulators of HIV transcription and latency reactivation
钙离子诱导的精子停止决定了哺乳动物的胚胎数量。	Watanabe, H.	PDF	N/A	Ca2+-evoked sperm cessation determines embryo number in mammals.
YAP/TAZ信号在由尿囊衍生的细胞中对于胎盘血管化是必需的。	Gao, S.	PDF	N/A	YAP/TAZ signaling in allantois-derived cells is required for placental vascularization
SOX2驱动结直肠癌中的胎儿重编程及可逆休眠	Baulies, A.	PDF	N/A	SOX2 drives fetal reprogramming and reversible dormancy in colorectal cancer
缺氧应激通过表观基因组和转录程序失调影响胶质瘤相关髓系细胞的功能。	Dzwigonska, M.	PDF	N/A	Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs
脂肪细胞鞘氨醇激酶1通过调节组蛋白修饰因子来破坏昼夜节律功能	Anderson, A.	PDF	N/A	Adipocyte sphingosine kinase 1 regulates histone modifiers to disrupt circadian function
空间转录组学揭示了弥漫性大B细胞淋巴瘤中与患者生存相关的免疫细胞生态系统	Herrero, A. D.	PDF	N/A	Spatial transcriptomics unveils immune cellular ecosystems associated with patient survival in diffuse large B-cell lymphoma
功能性磁共振成像显示，在大鼠大脑进行五天局部高密度θ波爆发刺激（hdTBS）后，脑活动出现区域性变化。	Li, Q.	PDF	N/A	Functional MRI reveals regional changes of brain activity after five days of focal high-density theta burst stimulation (hdTBS) of the rat brain
南阿拉斯加定居型虎鲸的多样化饮食在空间和时间上不同的觅食群体中发生了变化。	Myers, H.	PDF	N/A	The diverse diet of southern Alaska resident killer whales changes across spatiotemporally distinct foraging aggregations
澳大利亚维多利亚州中泥盆世豪威特山新种Groenlandaspis（甲胄鱼纲，节甲鱼目）独特的牙齿排列	Fitzpatrick, A. N.	PDF	N/A	Unique dental arrangement in a new species of Groenlandaspis (Placodermi, Arthrodire) from the Middle Devonian of Mount Howitt, Victoria, Australia
转录因子ZmbZIP75促进玉米籽粒灌浆和籽粒脱水	Long, T.	PDF	N/A	The transcription factor ZmbZIP75 promotes both grain filling and kernel dehydration in maize
TRPC3抑制改善了阿尔茨海默病中的突触功能障碍和记忆缺陷。	Liao, F.-F.	PDF	N/A	TRPC3 suppression ameliorates synaptic dysfunctions and memory deficits in Alzheimer's disease
纹状体间接通路介导犹豫	Geramita, M. A.	PDF	N/A	Striatal indirect pathway mediates hesitation
在注意力短暂调节过程中，跨感觉模式的共享皮层下觉醒系统	Khalaf, A.	PDF	N/A	Shared subcortical arousal systems across sensory modalities during transient modulation of attention
羧基端阻断sortilin结合可增强颗粒蛋白前体基因治疗，这可能成为治疗额颞叶痴呆的一种潜在疗法。	Kashyap, S. N.	PDF	N/A	Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia
少样本一致性神经解码（FALCON）基准算法	Karpowicz, B. M.	PDF	N/A	Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark
在追踪眼球运动期间，对再输入方向上的光动反应的抑制	Bachtoula, O.	PDF	N/A	Suppression of optokinesis in the reafferent direction during pursuit eye movements
闭合性头部损伤后，由少突胶质细胞前体细胞衍生的反应性星形胶质细胞形成的胶质瘢痕	Matsuda, H.	PDF	N/A	Glial scar formation by reactive astrocytes derived from oligodendrocyte progenitor cells after closed-head injury
胚胎期暴露于丙戊酸和新烟碱类物质会损害雏鸡端脑中间内侧隔区的发育性GABA转换，并影响局部回路中的长期增强效应。	Matsushima, T.	PDF	N/A	Embryonic exposure to valproic acid and neonicotinoid deteriorates the developmental GABA switch and impairs long-term potentiation in the local circuit of intermediate medial mesopallium of chick telencephalon
决策中的个体差异塑造了中边缘多巴胺如何调节选择信心和改变心意	Kocharian, A.	PDF	N/A	Individual differences in decision-making shape how mesolimbic dopamine regulates choice confidence and change-of-mind
高脂和致肥胖饮食对商业可用的小鼠脂肪肝疾病模型大脑体积的影响	Jiang, L.	PDF	N/A	The impact of high-fat and obesogenic diets on brain volume in a commercially available mouse model of fatty liver disease
果蝇幼虫运动回路的不同组成部分对胚胎关键期扰动的异质性反应	Krick, N.	PDF	N/A	Heterogeneous responses to embryonic critical period perturbations among different components of the Drosophila larval locomotor circuit
政策复杂性抑制了多巴胺反应	Gershman, S. J.	PDF	N/A	Policy complexity suppresses dopamine responses
人类睡眠期间，特定特征的预期处理逐渐减弱	Topalidis, P. I.	PDF	N/A	FEATURE-SPECIFIC ANTICIPATORY PROCESSING FADES DURING HUMAN SLEEP
利用面部表情和互信息自动去除MEG数据中的语音伪影	Tuomaala, S.	PDF	N/A	Automated speech artefact removal from MEG data utilizing facial gestures and mutual information
一种神经调质觉醒状态的Hopfield网络模型	Osman, M. A. M.	PDF	N/A	A Hopfield network model of neuromodulatory arousal state
遗传依赖的脑部韧性特征：童年虐待、遗传风险与脑功能之间的相互作用	Lu, H.	PDF	N/A	Genetic-Dependent Brain Signatures of Resilience: Interactions among Childhood Abuse, Genetic Risks and Brain Function
探索澳式橄榄球运动员功能连接的差异：一项关于默认模式网络的静息态fMRI研究	Tran, M.	PDF	N/A	Exploring Differences in Functional Connectivity in Australian Rules Football Players : A Resting-State fMRI Study on the Default Mode Network
谷氨酸能调控含miRNA的外泌体前体在皮层神经元中的转运和分泌	Bertolio, M.	PDF	N/A	Glutamatergic regulation of miRNA-containing exosome precursor trafficking and secretion from cortical neurons
电影引发的脑活动和连接性的遗传性	Gruskin, D. C.	PDF	N/A	Heritability of movie-evoked brain activity and connectivity
人类和狨猴大脑中的发声处理网络	Dureux, A.	PDF	N/A	Vocal processing networks in the human and marmoset brain
电压成像揭示了中缝核中与血清素介导的运动活力学习相关的电路计算	Kawashima, T.	PDF	N/A	Voltage imaging reveals circuit computations in the raphe underlying serotonin-mediated motor vigor learning
视神经挤压不会导致对侧眼的视网膜神经节细胞丢失。	Schoot Uiterkamp, F. E.	PDF	N/A	Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye.
探究Nogo受体同源物NgR2在建立耳蜗连接中的作用	Karagulyan, N.	PDF	N/A	Probing the role of Nogo receptor homolog NgR2 in setting up cochlear connectivity
全球性和分隔化的血清素控制对运动适应基础的传感器运动整合的影响	Haruvi, R.	PDF	N/A	Global and compartmentalized serotonergic control of sensorimotor integration underlying motor adaptation
调节前额叶皮层活动以缓解压力引起的工作记忆缺陷：一项经颅直流电刺激（tDCS）研究	Roy, S.	PDF	N/A	Modulating Prefrontal Cortex Activity to Alleviate Stress-Induced Working Memory Deficits: A Transcranial Direct Current (tDCS) Study
伏隔核核心翻译组伴随可卡因渴求孵化的变化	Kawa, A. B.	PDF	N/A	Changes in nucleus accumbens core translatome accompanying incubation of cocaine craving
猕猴大脑中功能和结构网络的年龄相关性改变	Ouchi, K.	PDF	N/A	Age-related alterations in functional and structural networks in the brain in macaque monkeys
连接组蛋白调控多能造血干细胞和祖细胞在髓系与淋巴系分化中的分支	Guo, S.	PDF	N/A	Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
Notch和LIM-同源域蛋白Arrowhead通过一种反馈机制相互调节，在果蝇的翅膀和神经发育中发挥作用。	Singh, J.	PDF	N/A	Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila
隔室的机械耦合驱动小鼠听觉上皮极性和模式的形成	Prakash, A.	PDF	N/A	Mechanical coupling of compartments drives polarity and patterning of mouse auditory epithelium
NR2F2对睾丸间质细胞向胎儿睾丸间质细胞分化的调控：对性别发育差异的见解	Estermann, M. A.	PDF	N/A	NR2F2 regulation of interstitial to fetal Leydig cell differentiation in the testis: insights into differences of sex development
亚马逊蜻蜓数量预测因子：胸温与生境特征	Calvao, L. B.	PDF	N/A	Thorax temperature and niche characteristics as predictors of abundance of Amazonian Odonata
北极植物与根际真菌之间的机会性合作选择受环境条件驱动。	Parisy, B.	PDF	N/A	Opportunistic partner choice among arctic plants and root-associated fungi is driven by environmental conditions.
用于自主接收网络中动物运动建模的粒子算法	Lavender, E.	PDF	N/A	Particle algorithms for animal movement modelling in autonomous receiver networks
鸣叫声表明长舌蝠的行为类型	Schabacker, T.	PDF	N/A	Vocalisations indicate behavioural type in Glossophagine bats
基于角色共享的协同群体行为分析：从实验任务到3对3篮球比赛的实际应用作为试点研究	Ichikawa, J.	PDF	N/A	Analysis of coordinated group behavior based on role-sharing: Practical application from an experimental task to a 3-on-3 basketball game as a pilot study
局部眼用VIAN-c4551抗血管生成肽治疗糖尿病性黄斑水肿：临床前疗效与眼部药代动力学	Adan-Castro, E.	PDF	N/A	Topical Ophthalmic Administration of VIAN-c4551 Antiangiogenic Peptide for Diabetic Macular Edema: Preclinical Efficacy and Ocular Pharmacokinetics
多巴胺释放位点的突触特化协调高效且精确的神经调节信号传递	Bulumulla, C.	PDF	N/A	Synaptic Specializations at Dopamine Release Sites Orchestrate Efficient and Precise Neuromodulatory Signaling
重新平衡老年人大脑的抑制系统：平衡学习对GABA能抑制和功能连接的影响	Liu, X.	PDF	N/A	Rebalance the inhibitory system in the elderly brain: Influence of balance learning on GABAergic inhibition and functional connectivity
位置信息在转录组学识别的神经元类型中驱动不同的特征	Shainer, I.	PDF	N/A	Positional information drives distinct traits in transcriptomically identified neuronal types
人类运动皮质中全身表征的马赛克	Deo, D. R.	PDF	N/A	A mosaic of whole-body representations in human motor cortex
定时喂食可改善脆性X综合征小鼠模型的行为表现并减少炎症。	Wang, H.-B.	PDF	N/A	Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome.
听觉皮层通过选择性多感官增强学习区分视听线索	Chang, S.	PDF	N/A	Auditory Cortex Learns to Discriminate Audiovisual Cues through Selective Multisensory Enhancement
同侧刺激显示，使用高密度功能性近红外光谱技术，在左侧初级体感皮层上，拇指和肩部的耳穴具有体位分布。	Okorie, E.	PDF	N/A	Ipsilateral stimulation shows somatotopy of thumb and shoulder auricular points on the left primary somatosensory cortex using high-density fNIRS
建立一个优化的、自动化的全脑神经元活动探测工作流程。	CABRERA, S.	PDF	N/A	Establishment of an optimized and automated workflow for whole brain probing of neuronal activity.
操纵注意力优先级在人类视觉皮层中产生了记忆与感觉表征之间的权衡	Rademaker, R. L.	PDF	N/A	Manipulating attentional priority creates a trade-off between memory and sensory representations in human visual cortex
微管在肌肉发育过程中协调线粒体运输与肌纤维形态发生	Avellaneda, J.	PDF	N/A	Microtubules coordinate mitochondria transport with myofibril morphogenesis during muscle development
细菌在动态珊瑚宿主上共存，存在竞争-定殖权衡	Gibbs, T.	PDF	N/A	Coexistence of bacteria with a competition-colonization tradeoff on a dynamic coral host
面向大规模博物馆基因组学项目：一种经济高效且高通量的方法，用于从博物馆昆虫标本中获取历史DNA	Holmquist, A. J.	PDF	N/A	Towards large-scale museomics projects: a cost-effective and high-throughput extraction method for obtaining historical DNA from museum insect specimens
高速4D荧光光场断层成像技术对自由活动生物体的整体成像	Zhou, K. C.	PDF	N/A	High-speed 4D fluorescence light field tomography of whole freely moving organisms
纤维状和无定形胶原蛋白相互渗透的网络促进了细胞的扩散和凝胶的稳定性。	Brunel, L. G.	PDF	N/A	Interpenetrating networks of fibrillar and amorphous collagen promote cell spreading and hydrogel stability
PEARL：重组乳酸菌蛋白洗脱海藻酸盐	Tadimarri, V. S.	PDF	N/A	PEARL: Protein Eluting Alginate with Recombinant Lactobacilli
最优传输通过基因速度估计揭示动态基因调控网络	Zhao, W.	PDF	N/A	Optimal transport reveals dynamic gene regulatory networks via gene velocity estimation
灵活且强大的高倍数组织图像细胞类型注释	Sun, H.	PDF	N/A	Flexible and robust cell type annotation for highly multiplexed tissue images
脑癌衍生因子对原代人脑周细胞的筛选活性	McCullough, S. J.	PDF	N/A	Screening activity of brain cancer-derived factors on primary human brain pericytes
在伊比利亚半岛上，遗传结构化的拟南芥（Arabidopsis thaliana）中，根分泌物成分的自然变异	Subrahmaniam, H. J.	PDF	N/A	Natural variation in root exudate composition in the genetically structured Arabidopsis thaliana in the Iberian Peninsula
模型显示，在接受奈玛特韦-利托那韦治疗后，SARS-CoV-2的反弹是由目标细胞的保留与不完全的病毒清除共同驱动的。	Phan, T.	PDF	N/A	Modeling suggests SARS-CoV-2 rebound after nirmatrelvir-ritonavir treatment is driven by target cell preservation coupled with incomplete viral clearance
空间微环境调节果蝇幼虫脂肪体中的免疫应答动态	Schlomann, B. H.	PDF	N/A	Spatial microenvironments tune immune response dynamics in the Drosophila larval fat body
致病相关真菌辅助染色体中的广泛染色体内重复	Dijkstra, J.	PDF	N/A	Extensive intrachromosomal duplications in a virulence-associated fungal accessory chromosome
塑料圈：塑料时代的海洋真菌群落	Kirstein, I.	PDF	N/A	The Plastisphere: Marine fungi communities in the plastics age
评估从烧焦土壤中分离嗜火细菌和真菌的最佳实践	Enright, D. J.	PDF	N/A	Evaluating Best Practices for Isolating Pyrophilous Bacteria and Fungi from Burned Soil
内共生体Rickettsiella viridis增加了Diuraphis noxia的毒性，但降低了有翅个体的频率。	Gu, X.	PDF	N/A	The endosymbiont Rickettsiella viridis increases the virulence of Diuraphis noxia but reduces alate frequency
DNA损伤应答与RNA聚合酶II调节因子Def1在细胞质中具有转录后功能	Akinniyi, O. T.	PDF	N/A	The DNA damage response and RNA Polymerase II regulator Def1 has posttranscriptional functions in the cytoplasm
扩张显微镜技术能够对血小板聚集物的结构组织进行定量表征。	Faulkner, E. L.	PDF	N/A	Expansion microscopy allows quantitative characterisation of structural organisation of platelet aggregates
不同的H3K9me3异染色质维持动态调控多能细胞中不同的基因程序和重复序列	Zhang, J.	PDF	N/A	Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programs and repeats in pluripotent cells
L1CAM SAX-7是一种Erk信号通路的拮抗调制剂。	Moseley-Alldredge, M.	PDF	N/A	The L1CAM SAX-7 is an antagonistic modulator of Erk signaling
间期染色体构象由特定的折叠程序决定，这些程序通过有丝分裂染色体或通过细胞质遗传。	Schooley, A.	PDF	N/A	Interphase chromosome conformation is specified by distinct folding programs inherited via mitotic chromosomes or through the cytoplasm
DeOri 10.0：实验鉴定真核生物复制起源的更新数据库	Zeng, Y.-H.	PDF	N/A	DeOri 10.0: An Updated Database of Experimentally Identified Eukaryotic Replication Origins
使用voomCLR评估单细胞研究中的差异细胞组成	Takele Assefa, A.	PDF	N/A	Assessing differential cell composition in single-cell studies using voomCLR
有丝分裂到G1期过渡过程中微隔室形成的动力学	Goel, V. Y.	PDF	N/A	Dynamics of microcompartment formation at the mitosis-to-G1 transition
彩虹蟒（Epicrates cenchria）收藏中多焦点皮肤肿瘤血管增生与蟒蛇包涵体病的关系	Broering Ferreira, A.	PDF	N/A	Multifocal cutaneous neoplastic vascular proliferations in a rainbow boa (Epicrates cenchria) collection with boid inclusion body disease
不同培养基中阴道毛滴虫的生长分析：利用大型语言模型（LLMs）预测和优化体外生长条件	Ferguson, S. L.	PDF	N/A	Growth Analysis of Trichomonas vaginalis in Different Culture Media: Leveraging Large Language Models (LLMs) to Predict and Optimize In Vitro Growth Conditions
无染色傅里叶叠层显微术与传统组织病理学光学显微术在肾小球膜性肾病中的比较分析	Valentino, M.	PDF	N/A	Comparative Analysis of Stain-Free Fourier Ptychographic Microscopy and Traditional Histopathological Light Microscopy in Renal Membranous Nephropathy
手术性甲状软骨复位对下颌前移和上气道塌陷性的影响	Tannous, H. J.	PDF	N/A	Surgical hyoid bone repositioning effects on mandibular advancement and upper airway collapsibility
在植物细胞器中利用工程化的合成P型PPR编辑因子实现从头RNA碱基编辑	Mathieu, S.	PDF	N/A	De novo RNA base editing in plant organelles with engineered synthetic P-type PPR editing factors
模块化纳米支架生物催化用于卓越的PET解聚和增值	Zhang, Y.	PDF	N/A	Modular Nano-Scaffold Biocatalysis for Superior PET Depolymerization and Valorization
解码溃疡性结肠炎中的细胞因子网络：识别致病机制与治疗靶点	Olbei, M. L.	PDF	N/A	Decoding Cytokine Networks in Ulcerative Colitis to Identify Pathogenic Mechanisms and Therapeutic Targets
通过ParB样BisD-CTP DNA夹钳在低频转移能力发育中实现的长距离基因激活	Antar, H.	PDF	N/A	Orchestrated long-distance gene activation by a ParB-like BisD-CTP DNA clamp in low-frequency transfer competence development in Pseudomonas putida
微生物群与气候：与生物气候相关的斑腿泛树蛙（Anura: Rhacophoridae）皮肤微生物多样性及群落功能	Meegaskumbura, M.	PDF	N/A	Microbiome and climate: Skin microbial diversity and community functions of Polypedates megacephalus (Anura: Rhacophoridae) associated with bioclimate
利用蚂蚁共生体制作酸奶揭示了用于食品发酵的细菌、酸和酶	Sinotte, V. M.	PDF	N/A	Making yogurt with the ant holobiont uncovers bacteria, acids, and enzymes for food fermentation
立克次体立克次体（Rickettsia rickettsii）编码一种分泌性脂酶，该脂酶有助于其在宿主细胞胞质内的定殖。	Sadik, M.	PDF	N/A	Rickettsia rickettsii encodes a secretory lipase that facilitates intracytosolic colonization in host cells.
结构引导的流感刺突纳米生物囊疫苗组装提供了泛H1鼻内保护	Myers, M. L.	PDF	N/A	Structure-guided assembly of an influenza spike nanobicelle vaccine provides pan H1 intranasal protection
活性细菌SIR2-STAND丝状体的冷冻电镜结构	Wang, Y.	PDF	N/A	Cryo-EM Structure of an Active Bacterial SIR2-STAND Filament
利用深度学习映射嗅觉受体与感知之间的组合编码	Chithrananda, S.	PDF	N/A	Mapping the combinatorial coding between olfactory receptors and perception with deep learning
利用分子模拟和图神经网络探索潜在的肠道产甲烷抑制剂	Aryee, R.	PDF	N/A	Exploring putative enteric methanogenesis inhibitors using molecular simulations and a graph neural network
基于探针捕获富集的全球病原体、呼吸道合胞病毒（RSV）和人诺如病毒（HuNoV）的完整基因组特征分析	Doddapaneni, H.	PDF	N/A	Complete Genomic Characterization of Global Pathogens, Respiratory Syncytial Virus (RSV), and Human Norovirus (HuNoV) Using Probe-based Capture Enrichment.
针对Pannexin 1的萘啶酮类化合物用于炎症性肠病管理	Hsueh, W.-Y.	PDF	N/A	Novel naphthyridones targeting Pannexin 1 for colitis management
在活细胞中进行RNA二级结构集合图谱绘制，识别出保守的RNA调控开关和温度计	Borovska, I.	PDF	N/A	RNA secondary structure ensemble mapping in a living cell identifies conserved RNA regulatory switches and thermometers
RalB 解偶联的外泌体介导内皮细胞魏贝尔-帕拉德小体的胞吐作用	Yang, M.	PDF	N/A	RalB uncoupled exocyst mediates endothelial Weibel-Palade body exocytosis
新型3D培养装置在人网膜脂肪细胞和手术衍生的巨噬细胞中的应用	Shimoji, M.	PDF	N/A	Application of novel 3D culture device for human omental adipocytes and macrophages derived from surgery
L-氨基酸氧化酶对细胞破坏的功能分析与综合机制	Prak, K.	PDF	N/A	Functional analyses and integrated mechanisms of cellular destruction by L-amino acid oxidase
结构重复检测器：通过显微镜技术实现分子复合物的多尺度定量映射	Mendes, A.	PDF	N/A	Structural Repetition Detector: multi-scale quantitative mapping of molecular complexes through microscopy
细胞质分裂沟的形成需要微管和Plk1的协同作用。	Day, C. A.	PDF	N/A	Commitment to cytokinetic furrowing requires the coordinate activity of microtubules and Plk1
MEK1/2激酶与c-Myc:MAX协同作用，防止多梳蛋白对人类多能干细胞中TERT的抑制	Kotian, S. T.	PDF	N/A	MEK1/2 kinases cooperate with c-Myc:MAX to prevent polycomb repression of TERT in human pluripotent stem cells
跨组织协调的SLC核苷转运体在秀丽隐杆线虫生殖调控中的作用	Guan, Y.	PDF	N/A	Cross-Tissue Coordination between SLC Nucleoside Transporters Regulates Reproduction in Caenorhabditis elegans
阳光照射的皮肤中普遍存在调控突变微克隆的诱导	Menon, V.	PDF	N/A	Pervasive Induction of Regulatory Mutation Microclones in Sun-exposed Skin
一种利用智能手机照片进行主成分分析识别牛奶掺假和Pb(II)污染情况的可能方法	Chandra, A. C.	PDF	N/A	A Potential Method for Identifying Milk Adulteration and Pb(II) Contamination Scenarios Using Principal Component Analysis from Smartphone Photographs
PP2A:B55-Eya3和PP2A:B55-p107的冷冻电镜结构定义了PP2A:B55底物招募	Padi, S. K.	PDF	N/A	Cryo-EM structures of PP2A:B55-Eya3 and PP2A:B55-p107 define PP2A:B55 substrate recruitment
MAPK/ERK信号通路在胶质瘤中调控干扰素反应、T细胞招募，增强肿瘤-小胶质细胞间的相互作用，并推动免疫检查点阻断疗法的疗效。	Kim, K.-S.	PDF	N/A	MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy.
# BioRxiv 2024-09-15 Papers

标题	作者	PDF链接	代码仓库	Title
进化上多样的穴样内陷蛋白共享一个围绕两亲性圆盘构建的共同结构框架。	Han, B.	PDF	N/A	Evolutionarily diverse caveolins share a common structural framework built around amphipathic discs
综合确定与亨廷顿病相关的突变型亨廷顿蛋白外显子1纤维的原子结构	Bagherpoor Helabad, M.	PDF	N/A	Integrative determination of the atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington's disease
人类病原体肺炎支原体和生殖支原体粘附复合体的动力学	Kawamoto, A.	PDF	N/A	Dynamics of the adhesion complex of the human pathogens Mycoplasma pneumoniae and Mycoplasma genitalium
细胞丝状体在细菌聚集和集群-集群组装中的作用	Charlton, S. G. V.	PDF	N/A	The role of cellular filamentation in bacterialaggregation and cluster-cluster assembly
使用线性图像解码器和非线性噪声抑制从人类大脑活动中重建的无语义视觉图像	Li, Q.	PDF	N/A	Visual Image Reconstructed Without Semantics from Human Brain Activity Using Linear Image Decoders and Nonlinear Noise Suppression
工程化酵母细胞模拟CD19+癌症，以控制CAR T细胞的激活	Deichmann, M.	PDF	N/A	Engineered yeast cells simulating CD19+ cancers to control CAR T cell activation
通过竞争性蛋白质二聚化网络进行计算的原理	Parres-Gold, J.	PDF	N/A	Principles of Computation by Competitive Protein Dimerization Networks
三种RING蛋白的不同且相互依赖的功能调控哺乳动物减数分裂中的重组过程。	Ito, M.	PDF	N/A	Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis
普罗克拉斯提斯图（Prokrustean Graph）：一种用于快速k-mer大小分析的子串索引	Park, A.	PDF	N/A	Prokrustean Graph: A substring index for rapid k-mer size analysis
一种动态系统方法用于最佳觅食	Chaturvedi, S.	PDF	N/A	A Dynamical Systems Approach to Optimal Foraging
表征差异成分分析（ReDisCA）	Ossadtchi, A.	PDF	N/A	Representational dissimilarity component analysis (ReDisCA)
鉴定调控腭发育的新基因	Bhaskar, A.	PDF	N/A	Identification of novel genes regulating the development of the palate
CD4+ T细胞在急性水缺乏型干眼模型中驱动角膜神经损伤，但并不引起上皮病变	Vereertbrugghen, A.	PDF	N/A	CD4+ T cells drive corneal nerve damage but not epitheliopathy in an acute aqueous-deficient dry eye model
改进六倍体小麦的基因组选择：亚基因组加性和上位性模型	Tessele, A.	PDF	N/A	Improving genomic selection in hexaploid wheat with sub-genome additive and epistatic models
前庭眼动反射的成熟并不依赖于感觉输入	Leary, P.	PDF	N/A	Sensation is Dispensable for the Maturation of the Vestibulo-ocular Reflex
PGE2合成/反应通路的破坏可抑制程序性细胞死亡-1（Pd-1）缺陷的高脂血症小鼠的动脉粥样硬化形成。	Ricciotti, E.	PDF	N/A	Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice
延长酶和去饱和酶编码基因的表达塑造了蜜蜂表皮碳氢化合物的特征	Rodriguez-Leon, D. S.	PDF	N/A	Expression of elongase- and desaturase-encoding genes shapes the cuticular hydrocarbon profiles of honey bees
GBA1 突变改变了神经元的放电和结构，调节了多巴胺神经元中的 VGLUT2 和 CRYAB	Rodriguez-Traver, E.	PDF	N/A	GBA1 mutations alter neuronal firing and structure, regulating VGLUT2 and CRYAB in dopamine neurons
神经肽催产素通过调节血流动力学和通透性，促进其从大脑到外周的摄取。	Rajamannar, P.	PDF	N/A	Neuropeptide oxytocin facilitates its own brain-to-periphery uptake by regulating blood flow dynamics and permeability
睡眠期间，脑淋巴系统清除功能得到增强。	Kroesbergen, E.	PDF	N/A	Glymphatic clearance is enhanced during sleep
SCRATCH：一种可编程、开源硬件的台式机器人，能够自动刮擦培养的组织，以研究细胞迁移、愈合和组织塑形。	Lin, Y.	PDF	N/A	SCRATCH: A programmable, open-hardware, benchtop robot that automatically scratches cultured tissues to investigate cell migration, healing, and tissue sculpting.
不那么自私：可移动元件助力适应气候变化	Potapenko, E. V.	PDF	N/A	Not so selfish: transposable elements fuel adaptation to climate change
线粒体过度活跃和活性氧驱动对黄热病病毒-17D减毒活疫苗的先天免疫反应	Muccilli, S. G.	PDF	N/A	Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine
鉴定影响CRISPR相关转座酶的蛋白质以增强基因组编辑	Song, L.	PDF	N/A	Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing
有丝分裂驱动蛋白-5是轴突生长的动态制动器	Lu, W.	PDF	N/A	'Mitotic' kinesin-5 is a dynamic brake for axonal growth
喷墨打印的石墨烯多电极阵列：体外心脏电生理学的可及平台	Lumpuy-Castillo, J.	PDF	N/A	Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology
番茄和茄子幼苗茎部软化和半透明形态学特征因感染拉尔氏假单胞菌F1C1所致	Bhuyan, S.	PDF	N/A	Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1
通过明胶-弹性纤维增强水凝胶进行阴道组织工程	Zambuto, S. G.	PDF	N/A	Vaginal Tissue Engineering via Gelatin-Elastin Fiber-Reinforced Hydrogels
ARHGEF3调节毛囊形态发生	Kalyanakrishnan, K.	PDF	N/A	ARHGEF3 Regulates Hair Follicle Morphogenesis
应激诱导小蛋白的翻译组学分析揭示了不同信号系统之间出乎意料的联系	Vellappan, S.	PDF	N/A	Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems
微生物群通过保护卵巢储备来延长生殖寿命	Munyoki, S. K.	PDF	N/A	The microbiota extends the reproductive lifespan by safeguarding the ovarian reserve
人类胎儿期前颅窝形态学评估及其临床意义。	Derkowski, W.	PDF	N/A	Morphometric evaluation of the anterior cranial fossa during the prenatal stage in humans and its clinical implications.
长末端重复序列逆转录转座子通过增强子捕获产生类似病毒的颗粒，导致发育中的肢体表型	Glaser, J.	PDF	N/A	Enhancer adoption by an LTR retrotransposongenerates viral-like particles causingdevelopmental limb phenotypes
适度激活线粒体未折叠蛋白反应可延长寿命，但不会增加对压力的抵抗力。	Di Pede, A.	PDF	N/A	Mild activation of the mitochondrial unfolded protein response increases lifespan without increasing resistance to stress
模拟有蹄类动物的夜间协调节律	Ukrow, J.	PDF	N/A	Modelling coordinated nocturnal rhythms in ungulates
蓝斑的α-2受体激动作用会损害由负向预测误差驱动的学习过程。	Lui, S. K. C.	PDF	N/A	Alpha-2 agonism of the locus coeruleus impairs learning driven by negative prediction error
使用模糊聚类对分级动物发声进行无监督分类	Benti, B.	PDF	N/A	Unsupervised classification of graded animal vocalisations using fuzzy clustering
利用人类测序、斑马鱼筛选和蛋白质结合微阵列技术鉴定眼部先天性颅神经运动神经元疾病的基因	Jurgens, J. A.	PDF	N/A	Gene identification for ocular congenital cranial motor neuron disorders using human sequencing, zebrafish screening, and protein binding microarrays
老年人中的优越感错觉：楔前叶的体积和功能连接性	Shidei, Y.	PDF	N/A	Superiority illusion in older adults: volume and functional connectivity of the precuneus
前额叶皮层和循环神经网络中反转学习的神经动力学	Kim, C. M.	PDF	N/A	Neural dynamics of reversal learningin the prefrontal cortex and recurrent neural networks
Cav3.1是POMC神经元中的亮氨酸传感器，介导食欲抑制和体重减轻。	Tsang, A. H.	PDF	N/A	Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and weight loss
数据驱动的1H-MRS基集成分的确定	Davies-Jenkins, C. W.	PDF	N/A	Data-driven determination of 1H-MRS basis set composition
目标记忆再激活引发了与纺锤波相关的时间压缩再激活	Abdellahi, M. E. A.	PDF	N/A	Targeted memory reactivation elicits temporally compressed reactivation linked to spindles
元意识、心智游移以及对“默认”外部和内部注意定向的控制	Christian, I. R.	PDF	N/A	Meta-awareness, mind-wandering, and the control of 'default' external and internal orientations of attention
在小脑的Crus I和II区域，浦肯野细胞在猴子学习基于强化的视动关联任务时，既编码视觉刺激，也编码即将做出的选择。	Ipata, A.	PDF	N/A	Purkinje cells in Crus I and II encode the visual stimulus and the impending choice as monkeys learn a reinforcement based visuomotor association task
用于分类神经元形态的深度学习：结合拓扑数据分析与图神经网络	Kanari, L.	PDF	N/A	Deep learning for classifying neuronal morphologies: combining topological data analysis and graph neural networks
超越脑电图起始瞬变：对模式眩光刺激的恒定呈现和消失的超兴奋性的敏感化和习惯化	Jefferis, T.	PDF	N/A	Beyond EEG Onset Transients: Sensitisation and Habituation of Hyper-excitation to Constant Presentation and Offset ofPattern-Glare Stimuli
通过放电率适应产生交替θ波扫描的系统模型	Ji, Z.	PDF	N/A	A systems model of alternating theta sweeps via firing rate adaptation
石榴籽油通过Keap1/Nrf2/NQO1通路对大鼠皮质短暂性大脑中动脉闭塞的预防作用	Li, D.	PDF	N/A	Preventive Effects of Pomegranate Seed Oil on Transient Middle Cerebral Artery Occlusion via the Keap1/Nrf2/NQO1 Pathway in the rats Cortex
小胶质细胞中的BRD4表达支持T细胞招募进入中枢神经系统，并加剧实验性自身免疫性脑脊髓炎（EAE）。	Dey, A.	PDF	N/A	BRD4 expression in microglia supports recruitment of T cells into the CNS and exacerbates EAE
反馈在应对渐进和突发视觉-本体感觉线索冲突中的作用	Babu, R.	PDF	N/A	The role of feedback in responding to gradual and abrupt visuo-proprioceptive cue conflict
用于视觉、眼动追踪和脑电图研究的高速OLED显示器，以实现精确刺激	Dimigen, O.	PDF	N/A	A high-speed OLED monitor for precise stimulation in vision, eye-tracking, and EEG research
发育过程中GABA水平降低导致斑马鱼幼体顶盖的连接性增加	Liu, Y.	PDF	N/A	Decreased GABA levels during development result in increased connectivity in the larval zebrafish tectum
昼夜节律的高度明显性与男性的负面情绪特质以及对惩罚相关信息增强的神经处理有关。	Scislewska, P.	PDF	N/A	High distinctness of circadian rhythm is related to negative emotionality and enhanced neural processing of punishment-related information in men
前扣带回（ACC）印记神经元的早期内在可塑性决定了记忆的形成和精确性	Hadzibegovic, S.	PDF	N/A	Early intrinsic plasticity of ACC engram neurons defines memory formation and precision
经颅电刺激可调节前庭系统	Laakso, I.	PDF	N/A	Transcranial electrical brain stimulation modulates the vestibular system
AAV介导的proneural因子表达在体内刺激成年Müller胶质细胞的神经发生。	Pavlou, M.	PDF	N/A	AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo.
不同行为相关的刺激在嗅觉系统中引发不同形式的适应	Nikolaev, A.	PDF	N/A	Different behaviourally relevant stimuli evoke different forms of adaptation in the olfactory system
在拉福拉病（一种严重的进行性肌阵挛性癫痫）的小鼠模型中，谷氨酸能和GABA能信号通路中的胶质细胞改变	Viana, R.	PDF	N/A	Glial alterations in the glutamatergic and GABAergic signaling pathways in a mouse model of Lafora disease, a severe form of progressive myoclonus epilepsy
相关和反相关双眼视差调节人脑视觉皮层中的GABA+和谷氨酸/谷氨酰胺浓度	Matuszewski, J.	PDF	N/A	Correlated and Anticorrelated Binocular Disparity Modulate GABA+ and Glutamate/glutamine Concentrations in the Human Visual Cortex
慢性中风中异常μ节律状态相关的皮层和皮层脊髓反应	Wischnewski, M.	PDF	N/A	Abnormal mu rhythm state-related cortical and corticospinal responses in chronic stroke
通过放电率适应动态调制海马回放序列	Ji, Z.	PDF	N/A	Dynamical Modulation of Hippocampal Replay Sequences through Firing Rate Adaptation
在帕金森病中，人类皮层-基底神经节网络在运动序列启动期间的学习相关振荡动力学	Presbrey, K. N.	PDF	N/A	Learning-related oscillatory dynamics in the human cortico-basal ganglia network during motor sequence initiation in Parkinson's Disease
病毒介导的传出抑制增强可减少野生型小鼠耳蜗的声损伤。	Slika, E.	PDF	N/A	Virally-Mediated Enhancement of Efferent Inhibition Reduces Acoustic Trauma in Wild Type Murine Cochleas.
Track-A-Worm 2.0：用于量化秀丽隐杆线虫运动、弯曲、睡眠及动作电位特性的软件套件	Vedantham, K.	PDF	N/A	Track-A-Worm 2.0: A Software Suite for Quantifying Properties of C. elegans Locomotion, Bending, Sleep, and Action Potentials
量化生物物理因素对通过残余功能网络塑造大脑交流的影响	Nakuci, J.	PDF	N/A	Quantifying the influence of biophysical factors in shaping brain communication through remnant functional networks
重复性磁刺激作用于运动皮层，通过抑制皮层内抑制的上调，损害平衡任务的巩固。	Egger, S.	PDF	N/A	Repetitive magnetic stimuli over the motor cortex impair consolidation of a balance task by suppressing up-regulation of intracortical inhibition
皮质内注射免疫检查点抑制剂促进单核细胞/巨噬细胞浸润，并恢复AD小鼠模型中的小胶质细胞功能和神经元活动	Park, T.	PDF	N/A	Intracortical injection of immune checkpoint inhibitor promotes monocyte/macrophage infiltration and restores microglial function and neuronal activity in an AD mouse model
用于离体和在体活细胞成像的等渗和微创光学透明介质	Inagaki, S.	PDF	N/A	Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo
横断面脑龄评估在预测未来脑变化方面存在局限性。	Korbmacher, M.	PDF	N/A	Cross-sectional brain age assessments are limited in predicting future brain change
SMN缺乏在脊髓性肌肉萎缩症的SMN{triangleup}7小鼠模型中，引发了早期非萎缩性肌病，导致骨骼肌纤维的收缩和兴奋耦合机制发生改变。	Berciano, M. T.	PDF	N/A	SMN deficiency induces an early non-atrophic myopathy with alterations in the contractile and excitatory coupling machinery of skeletal myofibers in the SMN{triangleup}7 mouse model of spinal muscular atrophy
在猕猴下丘中视觉诱发活动与听觉反应的变量调制	Schmehl, M. N.	PDF	N/A	Visually-evoked activity and variable modulation of auditory responses in the macaque inferior colliculus
在谷氨酸能神经元中失活Ndufs4揭示了Leigh综合征小鼠模型中吞咽呼吸失调	Huff, A. D.	PDF	N/A	Ndufs4 inactivation in glutamatergic neurons reveals swallow-breathing discoordination in a mouse model of Leigh Syndrome
人类NLRP3炎症小体激活导致在微管组织中心形成凝聚物	Wang, J.	PDF	N/A	Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center
秀丽隐杆线虫中的体细胞转甲状腺素相关蛋白通过维持精子完整性和适时排卵来调控生殖寿命	Wu, T.	PDF	N/A	Somatic Transthyretin-Related Proteins in C. elegans Govern Reproductive Longevity by Sustaining Sperm Integrity and Timely Ovulation
从胚胎鼻干细胞重建功能性嗅觉感觉组织	Suzuki, K.	PDF	N/A	Reconstruction of functional olfactory sensory tissue from embryonic nasal stem cells
果蝇雌激素相关受体促进幼虫脂肪体内的甘油三酯储存	Fasteen, T. D.	PDF	N/A	The Drosophila Estrogen-Related Receptor promotes triglyceride storage within the larval fat body
普遍存在的有方向性选择发现，实现了古DNA揭示人类适应性的承诺。	Akbari, A.	PDF	N/A	Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation
肌梭为运动序列提供灵活的感觉反馈。	Olson, W. P.	PDF	N/A	Muscle spindles provide flexible sensory feedback for movement sequences
基于正念的神经反馈：对EEG和fMRI研究的系统综述	Treves, I. N.	PDF	N/A	Mindfulness-based Neurofeedback: A Systematic Review of EEG and fMRI studies
在自发活动期间，神经血管脉冲响应函数（IRF）在不同皮质区域差异性地反映了内在的神经调节作用。	Rauscher, B. C.	PDF	N/A	Neurovascular Impulse Response Function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions
在记忆回忆和视觉感知过程中，对手的视觉空间编码结构在脑内侧顶叶皮层中进行反应。	Scrivener, C. L.	PDF	N/A	Opponent visuospatial coding structures responses during memory recall and visual perception in medial parietal cortex
自由生活的旋毛虫（Strongyloides）物种生命阶段的温度感觉行为有助于其在热带环境中的寄生。	Gregory, B. T.	PDF	N/A	Thermosensory behaviors of the free-living life stages of Strongyloides species support parasitism in tropical environments
自由生活的旋毛虫生命阶段的温度感应行为有助于其在热带环境中的寄生。	Gregory, B. T.	PDF	N/A	Thermosensory behaviors of the free-living life stages of Strongyloides species support parasitism in tropical environments
根据过去的和当前的照顾经历，对依恋模式叙事的神经和言语反应有所不同。	Lee, C. S.	PDF	N/A	Neural and verbal responses to attachment-schema narratives differ based on past and current caregiving experiences
杏仁核对不确定性下动态模型仲裁的贡献	Woo, J. H.	PDF	N/A	Contribution of amygdala to dynamic model arbitration under uncertainty
结合转录组学、连接性和活性分析，利用高度放大的多重原位杂交技术（hamFISH）对内侧杏仁核进行研究	Edwards, M. D.	PDF	N/A	Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH)
海马结构中以自我为中心的社会知识的锚定与调整	Rodriguez Aramendia, M.	PDF	N/A	Egocentric anchoring-and-adjustment of social knowledge in the hippocampal formation
SNc多巴胺能神经元中PKA-RIIβ水平的年龄相关性下降是PD发病的基础	Zhao, Y.	PDF	N/A	Age-related decline of PKA-RIIβ level in SNc dopaminergic neurons underlies PD pathogenesis
内源性G蛋白信号调节因子14（RGS14）抑制雌性小鼠中可卡因诱导的情感动机行为	Bramlett, S. N.	PDF	N/A	Endogenous Regulator of G protein Signaling 14 (RGS14) suppresses cocaine-induced emotionally motivated behaviors in female mice
使用物理信息神经网络建模感觉运动处理	Perez Rotondo, A.	PDF	N/A	Modeling Sensorimotor Processing with Physics-Informed Neural Networks
大麻和精神病对多巴胺系统的汇聚效应：一项针对大麻使用障碍和首发精神分裂症的纵向神经黑色素敏感MRI研究。	Ahrens, J.	PDF	N/A	Converging effects of cannabis and psychosis on the dopamine system: A longitudinal neuromelanin-sensitive MRI study in cannabis use disorder and first episode schizophrenia.
早期生活中接触多氯联苯的认知影响：涉及大脑多巴胺系统的性别特异性行为、激素和神经分子机制。	Hilz, E. N.	PDF	N/A	Cognitive effects of early life exposure to PCBs: Sex-specific behavioral, hormonal and neuromolecular mechanisms involving the brain dopamine system.
实践重塑了任务特化表征的几何结构与动态特性	Kikumoto, A.	PDF	N/A	Practice Reshapes the Geometry and Dynamics of Task-tailored Representations
海马相位依赖性刺激：一种计算建模方法	Lee, H.-P.	PDF	N/A	Phase-Dependent Stimulation of the Hippocampus: A Computational Modeling Approach
低温电子显微镜下的磷脂酶Cϵ结构揭示了N端结构域及其在活性中的作用	Samassekou, K.	PDF	N/A	Cryo-EM Structure of Phospholipase Cϵ Defines N-terminal Domains and their Roles in Activity
人类大脑中的注意力信息传递	Boroujeni, K. B.	PDF	N/A	Attentional Information Routing in The Human Brain
脑干回路控制小鼠类似咳嗽的气道防御行为	Xu, X.	PDF	N/A	A brainstem circuit controls cough-like airway defensive behaviors in mice
人类气道上皮细胞的单细胞分析揭示了细胞类型特异性对曲霉菌和球孢子菌的反应	Harding, A. T.	PDF	N/A	Single-cell analysis of human airway epithelium identifies cell type-specific responses to Aspergillus and Coccidioides
一种新型快速宿主细胞进入途径决定金黄色葡萄球菌的胞内命运	Rühling, M.	PDF	N/A	A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus
小胶质细胞特异性NF-κB信号传导是朊病毒诱导的胶质炎症和神经元损失的关键调节因子。	Hay, A. J. D.	PDF	N/A	Microglia-specific NF-κB signaling is a critical regulator of prion-induced glial inflammation and neuronal loss
评估咸海残留湖泊系统：盐度波动对浮游植物群落的影响	Malashenkov, D. V.	PDF	N/A	Assessing Aral Sea residual lake system: impact of fluctuating salinity on phytoplankton communities
逃离药物偏见陷阱：利用去偏设计提升药物-靶点相互作用预测的可解释性与泛化能力	Zhang, P.-D.	PDF	N/A	Escaping the drug-bias trap: using debiasing design to improve interpretability and generalization of drug-target interaction prediction
TopBP1生物分子凝聚物：晚期结直肠癌的新治疗靶点。	Morano, L.	PDF	N/A	TopBP1 biomolecular condensates: a new therapeutic target in advanced-stage colorectal cancer.
MITF在胃肠道间质瘤中的靶点：对自噬和细胞外囊泡分泌的启示	Proano-Perez, E.	PDF	N/A	MITF Targets in Gastrointestinal Stromal Tumors: Implication in Autophagy and Extracellular Vesicle Secretion
新型藻蓝蛋白体连接蛋白ApcI调控Synechocystis sp. PCC 6803的高光适应	Espinoza-Corral, R.	PDF	N/A	The new phycobilisome linker protein ApcI regulates high light adaptation in Synechocystis sp. PCC 6803
一种针对本科研究生的ChatGPT辅助阅读协议，用于参与生物物理学文献	Sambar, M.	PDF	N/A	A ChatGPT Assisted Reading Protocol for Undergraduate Research Students Engaging with Biophysics Literature
识别生长分化因子-15作为代谢功能障碍相关脂肪性肝炎的早期预测生物标志物：一项基于英国生物银行蛋白质组数据的嵌套病例对照研究	Wang, H.	PDF	N/A	Identification of Growth Differentiation Factor-15 as An Early Predictive Biomarker for Metabolic Dysfunction-Associated Steatohepatitis: A Nested Case-control Study of UK Biobank Proteomic Data
评估从黄芩提取物中分离出的反式肉桂酸在体内实验中的降血糖活性	Fedorova, A. M.	PDF	N/A	Assessment of the hypoglycemic activity of trans-cinnamic acid isolated from the extract of hairy rots Scutellaria baicalensis in in vivo experiments
对黑尿酸症的解剖学研究：对软骨和骨中褐黄病的全新见解	Hughes, J. H.	PDF	N/A	An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone
共转录RNA加工促进合子基因激活	Xu, J.	PDF	N/A	Co-transcriptional RNA processing boosts zygotic gene activation
免疫样糖链感知与横向获取的糖链加工在微生物共生中协同调控宿主控制	Jenkins, B. H.	PDF	N/A	Immune-like glycan-sensing and horizontally-acquired glycan-processing orchestrate host control in a microbial endosymbiosis
在Heliconius蝴蝶中特定模态的记忆增强	Hodge, E.	PDF	N/A	Modality specific memory enhancement in Heliconius butterflies
Megabouts：一种用于斑马鱼运动分析的灵活管道	Jouary, A.	PDF	N/A	Megabouts: a flexible pipeline for zebrafish locomotion analysis
睡眠-觉醒状态在老鼠大脑的情感调节区域中被编码	Walder-Christensen, K.	PDF	N/A	Sleep-wake states are encoded across emotion-regulation regions of the mouse brain
评估和比较非周期性神经活动的测量方法	Donoghue, T.	PDF	N/A	Evaluating and Comparing Measures of Aperiodic Neural Activity
利用跨试验和行为会话的相关性来改进神经解码	Zhang, Y.	PDF	N/A	Exploiting correlations across trials and behavioral sessions to improve neural decoding
灵长类灵巧手部运动的脊髓和皮质前运动控制	Takei, T.	PDF	N/A	Spinal and cortical premotor control of primate dexterous hand movements
多路复用推断的尖峰计数分析（SCAMPI）	Chen, Y.	PDF	N/A	Spike Count Analysis for MultiPlexing Inference (SCAMPI)
果蝇味觉回路的连接组分析	Walker, S. R.	PDF	N/A	Connectomic analysis of taste circuits in Drosophila
不同类型急性运动对皮质醇水平和认知功能影响的比较研究	Shao, Z.	PDF	N/A	Comparative study on the effects of different types of acute exercise on cortisol levels and cognitive functions
联会复合体在减数分裂期间保护双Holliday连接体	Tang, S. M.	PDF	N/A	Synaptonemal complex protects double-Holliday junctions during meiosis
应激颗粒的形成使癌细胞能够在无锚定条件下生存。	Yang, S.	PDF	N/A	Stress granule formation enables anchorage-independence survival in cancer cells
从头设计用于GPCR研究的融合蛋白工具	Gao, K.	PDF	N/A	De novo Design of A Fusion Protein Tool for GPCR Research
脂质囊泡中膜弯曲与拉伸的耦合	Wennerström, H.	PDF	N/A	On the coupling between membrane bending and stretching in lipid vesicles
条件定位药理学以时空精度操控细胞周期	Deng, C.	PDF	N/A	Conditional Localization Pharmacology Manipulates the Cell Cycle with Spatiotemporal Precision
PIP5K-Ras双稳态启动质膜对称性破坏，以调控细胞极性和迁移	Deng, Y.	PDF	N/A	PIP5K-Ras bistability initiates plasma membrane symmetry breaking to regulate cell polarity and migration
TAT-1是一种磷脂酰丝氨酸翻转酶，影响蜕皮过程并调控秀丽隐杆线虫表皮中的膜转运。	Milne, S. M.	PDF	N/A	TAT-1, a phosphatidylserine flippase, affects molting and regulates membrane trafficking in the epidermis of C. elegans
变异进化图：我们能否推断SARS-CoV-2变种的演变过程？	Das, B.	PDF	N/A	Variant Evolution Graph: Can We Infer How SARS-CoV-2 Variants are Evolving?
小乙型肝炎表面抗原的结构揭示了二聚体形成的机制	He, X.	PDF	N/A	Structure of small HBV surface antigen reveals mechanism of dimer formation
部分修复导致尿路梗阻逆转后，乳头结构和功能出现永久性缺陷。	Vanichapol, T.	PDF	N/A	Partial repair causes permanent defects in papillary structure and function after reversal of urinary obstruction
通过在酿酒酵母中的异源表达解码蓝细菌MysDs在类海藻氨基酸生物合成中的特异性	Zheng, X.	PDF	N/A	Decoding Specificity of Cyanobacterial MysDs in Mycosporine-Like Amino Acid Biosynthesis through Heterologous Expression in Saccharomyces cerevisiae
光触发的蛋白酶介导的合成细胞中肌动蛋白结合货物的释放	Akter, M.	PDF	N/A	Light-triggered protease-mediated release of actin-bound cargo from synthetic cells
肠道蠕虫通过使DC2向调节性表型发展，以对抗抗蠕虫免疫反应。	Andrusaite, A. T.	PDF	N/A	Intestinal helminth skews DC2 development towards regulatory phenotype to counter the anti-helminth immune response.
莱姆病病原体中RpoS与BosR之间的正反馈调节	Raghunandanan, S.	PDF	N/A	Positive feedback regulation between RpoS and BosR in the Lyme disease pathogen
HIV-1融合肽在CD4诱导的包膜开放过程中的构象轨迹	Thakur, B.	PDF	N/A	Conformational trajectory of the HIV-1 fusion peptide during CD4-induced envelope opening
两种与侵食松树的树皮甲虫相关的新物种Graphium（Microascales，子囊菌门）在中国被发现	Li, J.	PDF	N/A	Two new species of Graphium (Microascales, Ascomycota) associated with pine-infesting bark beetles in China
双歧杆菌青春双歧杆菌CCDM 368的多糖BAP1通过抑制小鼠Th2免疫减轻卵清蛋白诱导的过敏反应	Pacyga-Prus, K.	PDF	N/A	Polysaccharide BAP1 of Bifidobacterium adolescentis CCDM 368 attenuates ovalbumin-induced allergy through inhibition of Th2 immunity in mice
体外和体内HIV-1潜伏逆转通过Mukungulu，一种激活蛋白激酶C的非洲药用植物提取物	Richard, K.	PDF	N/A	Ex vivo and in vivo HIV-1 latency reversal by Mukungulu, a protein kinase C-activating African medicinal plant extract
基因密码扩展揭示了活细胞中位点特异性的乳酸化，重塑了蛋白质功能	Shao, C.	PDF	N/A	Genetic code expansion reveals site-specific lactylation in living cells reshapes protein function
细菌生长温度作为一种水平获得的聚基因性状	Farrell, A. A.	PDF	N/A	Bacterial growth temperature as a horizontally acquired polygenic trait
Tenascin C 缺失损害了肩袖修复后的肌腱愈合和功能恢复	TASHJIAN, R.	PDF	N/A	Tenascin C Deletion Impairs Tendon Healing and Functional Recovery After Rotator Cuff Repair
全面的蛋白质基因组学和空间分析：转移性黑色素瘤对免疫检查点阻断疗法的先天性和获得性抗性的研究	wei, s.	PDF	N/A	A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies
H2B单泛素化在同源重组修复过程中D-loop代谢中的多方面作用	Hung, S.-H.	PDF	N/A	Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair
Ripply3 过量使用通过在唐氏综合症模型中下调Tbx1，导致中面部缩短。	Ahumada Saavedra, J. T.	PDF	N/A	Ripply3 overdosage induces mid-face shortening through Tbx1 downregulation in Down syndrome models.
同源多倍体杂交揭示八倍体草莓的起源	Fan, Z.	PDF	N/A	Homoploid Hybridization Resolves the Origin of Octoploid Strawberries
发现并功能分析导致ROSAH综合征的新型ALPK1变异体	Snelling, T.	PDF	N/A	Discovery and functional analysis of a novel ALPK1 variant causing ROSAH syndrome
NuRD染色质重塑对于修复秀丽隐杆线虫生殖系中的外源性DSB是必需的。	Ananthaswamy, D.	PDF	N/A	NuRD chromatin remodeling is required to repair exogenous DSBs in the Caenorhabditis elegans germline
酵母中携带缺失的线粒体DNA的遗传偏倚：拷贝数与细胞内选择的作用	Kashko, N. D.	PDF	N/A	Inheritance bias of deletion-harbouring mtDNA in yeast: the role of copy number and intracellular selection
设计基于细胞的正交泛素转移级联系统以分析RBR E3 Parkin的底物	Fang, S.	PDF	N/A	Engineering a Cell-Based Orthogonal Ubiquitin Transfer Cascade for Profiling the Substrates of RBR E3 Parkin
通过3D生物打印组织特异性高细胞密度生物墨水进行工程化组织的生物制造	Jeon, O.	PDF	N/A	Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks
利用无细胞人羊膜进行小血管移植物的生物制造：一项在猪模型中的概念验证研究	Aung, O.	PDF	N/A	Biofabrication of Small Vascular Graft with Acellular Human Amniotic Membrane: A Proof-of-Concept Study in Pig
更新的AL-Base显示，在AL淀粉样变性中，免疫球蛋白轻链可变基因存在等级富集。	Morgan, G. J.	PDF	N/A	An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis
U2AF1 S34F通过与KRAS突变协同作用并改变对环境压力的反应，增强了肺细胞的肿瘤发生潜能。	Liang, C. E.	PDF	N/A	U2AF1 S34F enhances tumorigenic potential of lung cells by exhibiting synergy with KRAS mutation and altering response to environmental stress
揭示CRBN分子胶水在化学蛋白质组学中的隐藏相互作用网络	Baek, K.	PDF	N/A	Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics
番茄半胱氨酸蛋白酶抑制剂SlCYS8作为马铃薯干旱耐受性和块茎产量的触发因子	Dorval, M.	PDF	N/A	Tomato cystatin SlCYS8 as a trigger of drought tolerance and tuber yield in potato
在没有联网污水处理设施的地区，对土壤传播的蠕虫和其他肠道病原体进行环境监测。	Siko, J. E. E.	PDF	N/A	Environmental surveillance of soil-transmitted helminths and other enteric pathogens in settings without networked wastewater infrastructure
SMARCAD1调控与癌症突变热点相关的活性复制叉处的R-环	Uruci, S.	PDF	N/A	SMARCAD1 Regulates R-Loops at Active Replication Forks Linked to Cancer Mutation Hotspots
# BioRxiv 2024-09-14 Papers

标题	作者	PDF链接	代码仓库	Title
复杂非整倍体触发自噬和p53介导的凋亡，并损害人类植入前胚胎中的第二次谱系分离	Regin, M.	PDF	N/A	Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
GEARBOCS：一种用于星形胶质细胞体内基因编辑的腺相关病毒工具	Sivadasan Bindu, D.	PDF	N/A	GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
肉食性有袋动物颅面发育过程中的基因调控动态	Cook, L. E.	PDF	N/A	Gene regulatory dynamics during craniofacial development in a carnivorous marsupial
从自运动信号中抄近路：量化开放迷宫中的轨迹和主动感知	Xu, J.	PDF	N/A	Shortcutting from self-motion signals: quantifying trajectories and active sensing in an open maze
稳态突触归一化优化了神经群体编码网络模型中的学习	Mayzel, J.	PDF	N/A	Homeostatic synaptic normalization optimizes learning in network models of neural population codes
睾酮通过膜蛋白GPRC6A在斑马鱼胚胎中引起心脏水肿	Zadmajid, V.	PDF	N/A	Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos
G蛋白偶联受体TBXA2R激活ERM蛋白以调控三阴性乳腺癌细胞的迁移和侵袭。	Leguay, K.	PDF	N/A	The G protein-coupled receptor TBXA2R activates ERMs to control cell motility and invasion of triple-negative breast cancer cells.
CAMP：一个模块化的宏基因组分析系统，用于综合的多步骤数据探索	Mak, L.	PDF	N/A	CAMP: A modular metagenomics analysis system for integrated multi-step data exploration
前额叶皮层第五层锥体神经元的特定亚型中存在特定异构体的烟碱样反应	Patel, A. V.	PDF	N/A	Isoform-specific nicotinic responses are present in distinct subtypes of prefrontal layer V pyramidal neurons
一种毫秒级粗粒度模拟方法用于解析大麻素在甘氨酸受体α1上的别构结合	Bartocci, A.	PDF	N/A	A millisecond coarse-grained simulation approach to decipher allosteric cannabinoid binding at the glycine receptor α1
大型生物银行队列中随访数据的分析：方法学综述	Kolde, A.	PDF	N/A	Analysis of follow-up data in large biobank cohorts: a review of methodology
DNA修复背景与目标序列的相互作用可预测地偏向于Cas9生成的突变。	Pallaseni, A.	PDF	N/A	The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations
溶酶体的外周定位支持黑色素瘤的侵袭性	Jerabkova-Roda, K.	PDF	N/A	Peripheral positioning of lysosomes supports melanoma aggressiveness
Fragle：利用深度学习对片段组学特征进行泛癌种循环肿瘤DNA定量	Jacobsen Skanderup, A.	PDF	N/A	Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles
下一代杀虫剂氟吡呋喃酮与真菌病原体的协同效应	Schlaeppi, D.	PDF	N/A	Synergistic effects of the next generation insecticide flupyradifurone with a fungalpathogen
VACmap：一种用于解析复杂基因组重排的精确长读对齐工具	Ding, H.	PDF	N/A	VACmap: An Accurate Long-Read Aligner for Unraveling Complex Genomic Rearrangements
时间和奖励的竞争性整合解释了价值敏感的觅食决策以及前额叶皮层的渐进动力学	Bukwich, M.	PDF	N/A	Competitive integration of time and reward explains value-sensitive foraging decisions and frontal cortex ramping dynamics
亲吻素纤维及其受体分布分析表明，其在中枢感觉处理和行为状态控制中可能发挥作用。	Zhang, L.	PDF	N/A	Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
揭示区间通讯信号轴：线粒体至内质网应激反应（MERSR）及其对蛋白质稳态的影响	Li, J. J.	PDF	N/A	Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis
健康老龄化中流体智力功能补偿的神经证据	Knights, E.	PDF	N/A	Neural Evidence of Functional Compensation for Fluid Intelligence in Healthy Ageing
早期植入前酒精暴露后小鼠胎盘中性别特异性DNA甲基化和基因表达变化	Legault, L.-M.	PDF	N/A	Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure
在空间解析的组学数据中，表征细胞类型在不同尺度上的空间关系	dos Santos Peixoto, R.	PDF	N/A	Characterizing cell-type spatial relationships across length scales in spatially resolved omics data
芳香烃受体限制背根神经节神经元在损伤后的轴突再生	Halawani, D.	PDF	N/A	Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury
视前区控制遗传性癫痫小鼠模型中与睡眠相关的癫痫发作起始	Potesta, C. V.	PDF	N/A	Preoptic area controls sleep-related seizure onset in a genetic epilepsy mouse model
泛素特异性蛋白酶USP8的时空招募指导了内体成熟过程	Miao, Y.	PDF	N/A	Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation
TimberTracer：一个综合框架，用于评估森林管理和采伐木材产品替代对碳固存的影响。	Boukhris, I.	PDF	N/A	TimberTracer: A Comprehensive Framework for the Evaluation of Carbon Sequestration by Forest Management and Substitution of Harvested Wood Products.
微管干扰后iPSC衍生模型系统中神经突延伸和核运动的测量	Sebastien, M.	PDF	N/A	Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation
尼帕病毒融合蛋白的纳米级结构揭示了新的膜融合机制。	Wang, Q.	PDF	N/A	The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms.
MolSnapper：基于结构的药物设计中的条件扩散	Ziv, Y.	PDF	N/A	MolSnapper: Conditioning Diffusion for Structure Based Drug Design
栖息地破碎化介导了鸟类长期气候驱动的热嗜性机制	Liu, J.	PDF	N/A	Habitat fragmentation mediates the mechanisms underlying long-term climate-driven thermophilization in birds
催化功能不同的IDH1突变体在肿瘤模型中调节表型严重性	Adam, M. A. A.	PDF	N/A	Catalytically distinct IDH1 mutants tune phenotype severity in tumor models
沙眼衣原体的T3SS结构基因和效应基因在不同的表型细胞形态中表达。	Grieshaber, N.	PDF	N/A	The T3SS structural and effector genes of Chlamydia trachomatis are expressed in distinct phenotypic cell forms.
长精子优先权与果蝇（Drosophila melanogaster）中其他隐秘的雌性选择	Peckenpaugh, B.	PDF	N/A	Long-sperm precedence and other cryptic female choices in Drosophila melanogaster
SLC35G1：一种高度氯离子敏感的转运蛋白，负责肠上皮细胞基底侧膜的柠檬酸盐吸收转运。	Mimura, Y.	PDF	N/A	SLC35G1: A highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption
有丝分裂期间PI(3,5)P2不对称性对于不对称液泡遗传至关重要	Huda, M.	PDF	N/A	PI(3,5)P2 asymmetry during mitosis is essential for asymmetric vacuolar inheritance
青少年时期大脑形态与认知功能之间的关联：基于9至15岁全面大规模分析的见解	Yan, J.	PDF	N/A	Association between Brain Morphometry and Cognitive Function during Adolescence: Insights from a Comprehensive Large-Scale Analysis from 9 to 15 Years Old
MIROSLAV：一个完整的开源硬件和软件工具包，用于啮齿动物高吞吐量昼夜节律活动测量和分析	Virag, D.	PDF	N/A	MIROSLAV: A complete open-source hardware and software toolkit for high-throughput circadian activity measurement and analysis in rodents
B细胞受体依赖性增强登革病毒感染	Gebo, C.	PDF	N/A	B cell receptor dependent enhancement of dengue virus infection
TRPML1门控通过别构突变和脂质的调节	Gan, N.	PDF	N/A	TRPML1 gating modulation by allosteric mutations and lipids
刺胞动物XIAP激活半胱天冬酶介导的细胞死亡	Chen, Y.	PDF	N/A	Cnidaria XIAP activates caspase-mediated cell death
直接从梨状皮层到听觉皮层的投射塑造了听觉与嗅觉的整合	Vogler, N. W.	PDF	N/A	Direct piriform-to-auditory cortical projections shape auditory-olfactory integration
理解压力变性的物理决定因素：利用高压核磁共振技术探究Yfh1在不同温度下的展开途径	Roumestand, C.	PDF	N/A	Understanding the physical determinants of pressure denaturation: Exploring the unfolding pathways of Yfh1 at different temperatures with High-Pressure NMR
CRISPR RNA结合驱动结构有序化，为Cas7-11的靶标切割做好准备	Lin, C. P.	PDF	N/A	CRISPR RNA binding drives structural ordering that primes Cas7-11 for target cleavage
不同表型水稻干旱和盐胁迫公共RNA测序数据的Meta分析	Shintani, M.	PDF	N/A	Meta-analysis of public RNA-sequencing data of drought and salt stresses in different phenotypes of Oryza sativa
肾癌细胞通过吞噬作用和水平基因转移获取免疫表面蛋白	Marcarian, H. Q.	PDF	N/A	Renal cancer cells acquire immune surface protein through trogocytosis and horizontal gene transfer
无序蛋白质及其凝聚物的酶促磷酸化分子模拟	Zippo, E.	PDF	N/A	Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates
单胺氧化酶C（MAO C）的进化与功能分析：MAO基因家族的新成员	Merello, G.	PDF	N/A	Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family
原子级自由能景观揭示了蜜二糖转运蛋白的协同共转运机制	Liang, R.	PDF	N/A	Atomic-Level Free Energy Landscape Reveals Cooperative Symport Mechanism of Melibiose Transporter
电鳗（Electrophorus）电器官中由腹侧向背侧的电细胞发育。	Senarat, S.	PDF	N/A	Ventral-to-dorsal electrocyte development in electric organs of electric eel (Electrophorus).
评估用于跨癌症适应症比较蛋白质表达的计算方法	Wang, J.	PDF	N/A	Evaluating computational approaches for comparison of protein expression across cancer indications
AlphaFold2 SLiM筛选自噬中LC3-LIR相互作用	Stuke, J. F. M.	PDF	N/A	AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy
小鼠心脏中伴侣蛋白复合物的年龄相关变化	Bhat, P. D.	PDF	N/A	Age-dependent Changes in a Chaperone Complex in the Mouse Heart
白色念珠菌与粪肠球菌之间的跨菌种宿主细胞协同损伤	Kapitan, M.	PDF	N/A	Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis
CNValidatron，利用计算机视觉实现CNV调用的自动化验证	Montalbano, S.	PDF	N/A	CNValidatron, automated validation of CNV calls using computer vision
使用结构方程模型预测噪声中语音识别能力：基于静态与动态听觉图形-背景分析	Guo, X.	PDF	N/A	Predicting speech-in-noise ability with static and dynamic auditory figure-ground analysis using structural equation modelling
在海马体的循环网络模型中，条形码活动能够实现高效的记忆绑定。	Fang, C.	PDF	N/A	Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding
番茄和茄子幼苗茎部软化和半透明形态学特征，由Ralstonia pseudosolanacearum F1C1感染引起	Bhuyan, S.	PDF	N/A	Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1
Colora：一个用于完成染色体规模从头基因组组装的Snakemake工作流程	Obinu, L.	PDF	N/A	Colora: A Snakemake Workflow for Complete Chromosome-scale De Novo Genome Assembly
骨附着土壤作为目标和环境DNA及蛋白质的来源	de Dios Martinez, T.	PDF	N/A	Bone adhered soil as a source of target and environmental DNA and proteins
解剖变异及其他血管因素对筛板低氧的影响	Lu, Y.	PDF	N/A	Impact of anatomic variability and other vascular factors on lamina cribrosa hypoxia
使用单细胞RNA测序数据的拷贝数变异推断方法基准研究	Chen, X.	PDF	N/A	A benchmarking study of copy number variation inference methods using single-cell RNA-sequencing data
spaDesign：一种改进基于测序的空间转录组学实验设计的统计框架	Xie, J.	PDF	N/A	spaDesign: A Statistical Framework to Improve the Design of Sequencing-based Spatial Transcriptomics Experiments
Convpaint - 使用预训练神经网络进行交互式像素分类的通用框架	Hinderling, L.	PDF	N/A	Convpaint - Universal framework for interactive pixel classification using pretrained neural networks
增强NADPH以恢复G6PD缺乏的微胶质细胞中的氧化还原稳态和溶酶体功能	Mondal, A.	PDF	N/A	Enhancing NADPH to Restore Redox Homeostasis and Lysosomal Function in G6PD-Deficient Microglia
环境介导的相互作用导致微生物中外部化和集体记忆的形成	Gajrani, S.	PDF	N/A	Environment-mediated interactions cause an externalized and collective memory in microbes
拟病毒、类Sputnik病毒和转拟病毒之间的寄生和共生相互作用：理论和动力系统方法。	ORTEGA ATEHORTUA, E.	PDF	N/A	Parasitic and Commensal interactions among Mimiviruses, Sputnik-like virophages, and Transpovirons: A theoretical and dynamical systems approach.
肌因子FGF21与ALS中增强的生存率相关，并能减轻应激诱导的细胞毒性。	Guha, A.	PDF	N/A	The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity
人类视觉皮层在准备期间的双格式注意力模板	Chen, Y.	PDF	N/A	Dual-format attentional template during preparation in human visual cortex
人类气味辨别学习中特异性和迁移的对比模式	Chang, X.	PDF	N/A	Contrasting patterns of specificity and transfer in human odor discrimination learning
酒精和可卡因滥用对成人海马体神经元和非神经元细胞周转的影响	Alkass, K.	PDF	N/A	Effect of Alcohol and Cocaine Abuse on Neuronal and Non-Neuronal Cell Turnover in the Adult Human Hippocampus
缺乏皮质抑素会加重中风后的神经功能损伤，并加剧与衰老相关的神经胶质和血管功能障碍。	Castillo Gonzalez, J.	PDF	N/A	Lack of cortistatin worsens neurological outcome and exacerbates aging-related glial and vascular dysfunction in stroke
枝角类物种的共存如何影响它们的肠道微生物群？	Houwenhuyse, S.	PDF	N/A	How does co-occurrence of Daphnia species affect their gut microbiome?
在长期石灰性草地实验中，绵羊放牧并未增强土壤碳的持久性。	Encarnation, D.	PDF	N/A	No enhancement of soil carbon persistence by sheep grazing in a long-term calcareous grassland experiment
扩展表型影响社会性蜘蛛的集体行为和生存	Parthasarathy, B.	PDF	N/A	Extended Phenotype Influences Collective Behaviour and Survival in a Social Spider
比较转录组和变异分析揭示了肥胖型2型糖尿病大鼠模型胰腺胰岛中脂质运载蛋白2基因的常见分布无义突变	Yokoi, N.	PDF	N/A	Comparative transcriptome and variant analyses of the pancreatic islets of a rat model of obese type 2 diabetes identifies a frequently distributed nonsense mutation in the lipocalin 2 gene
茄科植物的全基因组和全遗传学揭示了同源基因在作物工程中的偶然性	Benoit, M.	PDF	N/A	Solanum pan-genomics and pan-genetics reveal paralogs as contingencies in crop engineering
提出一种以轴突为中心的分析方法，用于研究眼内压引起的机械损伤	Bansal, M.	PDF	N/A	Proposing a methodology for axon-centric analysis of IOP-induced mechanical insult
注意力机制和状态空间基因组语言模型中标记化影响的比较	Lindsey, L. M.	PDF	N/A	A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models
揭示单细胞Hi-C数据中的多尺度建筑特征：使用scCAFE方法	Wang, F.	PDF	N/A	Unveiling multi-scale architectural features in single-cell Hi-C data using scCAFE
ProtRNA：一种通过跨模态迁移学习生成的蛋白质衍生RNA语言模型	Zhang, R.	PDF	N/A	ProtRNA: A Protein-derived RNA Language Model by Cross-Modality Transfer Learning
m6AConquer：一个用于m6A检测技术统一量化与整合的数据资源	Zhao, X.	PDF	N/A	m6AConquer: a Data Resource for Unified Quantification and Integration of m6A Detection Techniques
新皮层和海马体的θ振荡追踪视听整合及言语记忆的重播	Biau, E.	PDF	N/A	Neocortical and hippocampal theta oscillations track audiovisual integration and replay of speech memories
聚焦超声增强抗体递送用于帕金森病的治疗	Kwon, N.	PDF	N/A	Focused ultrasound enhanced antibody delivery for the treatment of Parkinson's Disease
视黄酸介导的稳态可塑性驱动伏隔核核心细胞类型特异性CP-AMPAR积累及可卡因渴求的孵化	Hwang, E.-K.	PDF	N/A	Retinoic acid-mediated homeostatic plasticity drives cell type-specific CP-AMPAR accumulation in nucleus accumbens core and incubation of cocaine craving
较低的感知压力水平在自然处理过程中增强了感知和注意皮层的神经同步性。	Craig, J.	PDF	N/A	Lower perceived stress enhances neural synchrony in perceptual and attentional cortices during naturalistic processing
在声音新奇性的进化过程中，运动皮层投射的选择性扩展	Isko, E. C.	PDF	N/A	Selective expansion of motor cortical projections in the evolution of vocal novelty
操作性酒精自我给药方式通过调节伏隔核中含GluA2的AMPAR表达和突触活性，从而增强药物的强化特性。	Faccidomo, S.	PDF	N/A	Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug
认知功能的调节器：小脑通过整合作用修改人类皮层网络动力学	Bansal, K.	PDF	N/A	A modulator of cognitive function: Cerebellum modifies human cortical network dynamics via integration
不同的基底神经节决策动力学在冲突和不确定性下	Ging-Jehli, N. R.	PDF	N/A	Distinct basal ganglia decision dynamics under conflict and uncertainty
视觉运动学习中的节省与小脑-丘脑-皮质网络内的连接性变化相关，该网络编码运动误差。	Struber, L.	PDF	N/A	Savings in visuomotor learning is associated with connectivity changes within a cerebello-thalamo-cortical network encoding movement errors
神经肌肉骨骼建模揭示了感觉运动皮层中适应性学习的肌肉水平神经动态	DeWolf, T.	PDF	N/A	Neuro-musculoskeletal modeling reveals muscle-level neural dynamics of adaptive learning in sensorimotor cortex
CHCHD2-CHCHD10蛋白复合物受线粒体功能障碍的调节，并改变小鼠大脑中的脂质稳态。	Gerlach, J.	PDF	N/A	The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain.
纵向多组学免疫分析揭示了健康成年人中与年龄相关的免疫细胞动态变化	Gong, Q.	PDF	N/A	Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults
利用位点频率比区分选择性与非选择性力量	Hey, J.	PDF	N/A	Isolating selective from non-selective forces using site frequency ratios
基于基因的适应性模型及其对遗传变异的启示	Johri, P.	PDF	N/A	A gene-based model of fitness and its implications for genetic variation
推动单分子转录组测序的极限，以揭示人类视网膜神经中最大的疾病相关转录本异构体	Stemerdink, M.	PDF	N/A	Pushing the limits of single molecule transcript sequencing to uncover the largest disease-associated transcript isoforms in the human neural retina
行为证据表明存在两种注意模式	Gupta, A.	PDF	N/A	Behavioral Evidence for Two Modes of Attention
篮状细胞中的双峰树突处理驱动与记忆相关的不同振荡	Tzilivaki, A.	PDF	N/A	Bimodal dendritic processing in basket cells drives distinct memory-related oscillations
一种应激诱导的逆行线粒体运输的分子开关	Gladkova, C.	PDF	N/A	A molecular switch for stress-induced activation of retrograde mitochondrial transport
CD11B+CD36+细胞是促进骨形成的巨噬细胞，能够限制与年龄相关的骨质流失。	Koroth, J.	PDF	N/A	CD11B+CD36+ cells are bone anabolic macrophages that limit age-associated bone loss
CD34+基质细胞/端粒细胞在中年斯普拉格-道利大鼠心肌梗死后愈合过程中表现出动态分布模式	Schneider, D. T.	PDF	N/A	CD34+ Stromal Cell/Telocytes Demonstrate a Dynamic Pattern of Distribution During Healing of Post-Infarcted Myocardium in Middle-Aged Sprague-Dawley Rats
分析细胞中异常折叠状态蛋白质纤维化的生理影响	Levin, T.	PDF	N/A	Profiling the physiological impact of aberrant folded-state protein filamentation in cells
神经纤维瘤蛋白丢失通过GLUT1激活诱导炎症性巨噬细胞表型转换和视网膜新生血管形成	ZAIDI, Y.	PDF	N/A	Loss of Neurofibromin Induces Inflammatory Macrophage Phenotypic Switch and Retinal Neovascularization via GLUT1 Activation
细胞应激对SERPINA1 3'UTR中改变的多聚腺苷酸化位点使用影响A1AT蛋白表达	Jiamutai, F.	PDF	N/A	Altered polyadenylation site usage in SERPINA1 3'UTR in response to cellular stress affects A1AT protein expression
急性西地那非给药可降低绵羊对诱发性心房颤动的易感性	denham, N.	PDF	N/A	Acute sildenafil administration reduces susceptibility to induced atrial fibrillation in sheep
多层记忆痕迹中的任务相关表征格式	Heinen, R.	PDF	N/A	Task-relevant representational formats in multi-layered memory traces
行为谱显示，大鼠对一种恐惧条件下的视觉线索表现出多样行为的组织能力。	Williams, D. C.	PDF	N/A	Ethograms reveal a fear conditioned visual cue to organize diverse behaviors in rats
人微小RNA-153-3p靶向特定的神经元基因，并与阿尔茨海默病的风险相关。	Wang, R.	PDF	N/A	Human microRNA-153-3p targets specific neuronal genes and is associated with the risk of Alzheimer's disease.
精神分裂症患者免疫细胞中IKZF1-IKZF2串联的双重打击调节特定症状	Ballasch, I.	PDF	N/A	A double hit affecting the IKZF1-IKZF2 tandem in immune cells of schizophrenic patients regulate specific symptoms
表观遗传适应驱动单核细胞在移植入视网膜后分化为类似小胶质细胞的细胞	Liu, J.	PDF	N/A	Epigenetic adaptation drives monocyte differentiation into microglia-like cells upon engraftment into the retina
用于可预测、精确的双水平调控哺乳动物重组蛋白表达的合成G四链体元件	Pohle, M.	PDF	N/A	Synthetic G-quadruplex components for predictable, precise two-level control of mammalian recombinant protein expression
肽激动剂解离和粘附G蛋白偶联受体失活的机制	Joshi, K.	PDF	N/A	Mechanisms of peptide agonist dissociation and deactivation of adhesion G-protein-coupled receptors
初级纤毛促进EMT诱导的三阴性乳腺癌肿瘤异质性和对治疗的抵抗性	Tessier, C.	PDF	N/A	Primary cilia promote EMT-induced triple-negative breast tumor heterogeneity and resistance to therapy
NEK9敲除通过诱导ERK介导的癌细胞焦亡重塑多西他赛耐药性	Ansari, S. A.	PDF	N/A	NEK9 ablation rewires docetaxel resistance through induction of ERK-mediated cancer cell pyroptosis
RAD50是一种潜在的乳腺癌诊断和预后生物标志物。	Chhatwal, K. S.	PDF	N/A	RAD50 is a potential biomarker for breast cancer diagnosis and prognosis
通过理性受体工程解锁扩展的鞭毛蛋白感知	Li, T.	PDF	N/A	Unlocking expanded flagellin perception through rational receptor engineering
高脂饮食对小鼠下丘脑反应的性别依赖性影响	Dreux, V.	PDF	N/A	Sex-dependent effects of a high-fat diet on the hypothalamic response in mouse
TAAR1部分激动剂诱导的觉醒通过多巴胺能神经传递介导	Park, S.	PDF	N/A	Wakefulness induced by TAAR1 partial agonism is mediated through dopaminergic neurotransmission
通过电子断层扫描技术对脑内皮细胞的超微结构进行分析	Kotchetkov, P.	PDF	N/A	Ultrastructural analysis of the brain endothelium by electron tomography
在正常生理条件下，基于统计稳健性的轴突髓鞘单元模型及其在疾病状态中的应用	Gow, A.	PDF	N/A	A Statistically-Robust Model Of The Axomyelin Unit Under Normal Physiologic Conditions With Application To Disease States
分带运动适应相关的皮层-肌肉耦合的调制	Oshima, A.	PDF	N/A	Modulation of cortico-muscular coupling associated with split-belt locomotor adaptation
刺伤伤口引发实质性星形胶质细胞中的过渡放大祖细胞样表型	Ninkovic, J.	PDF	N/A	Stab Wound Injury Elicits Transit Amplifying Progenitor-like Phenotype in Parenchymal Astrocytes
通过蛋白质语言模型从氨基酸序列预测蛋白质半衰期	Sagawa, T.	PDF	N/A	Prediction of Protein Half-lives from Amino Acid Sequences by Protein Language Models
一个用于SubtiWiki的新框架，SubtiWiki是模式生物枯草芽孢杆菌的数据库	Elfmann, C.	PDF	N/A	A new framework for SubtiWiki, the database for the model organism Bacillus subtilis
识别、优先排序和可视化功能性启动子单核苷酸变异（SNVs）：使用复发无关的REMIND-Cancer管道和pSNV Hunter	Abad, N. A. B.	PDF	N/A	Identifying, Prioritizing, and Visualizing Functional Promoter SNVs with the Recurrence-agnostic REMIND-Cancer Pipeline and pSNV Hunter
针对施万细胞EP2/cAMP纳米域以阻断疼痛但不阻断炎症	Nassini, R.	PDF	N/A	Targeting the Schwann Cell EP2/cAMP Nanodomain to Block Pain but not Inflammation
靶向细胞器中蛋白酶激活受体2信号的纳米药物提供持续镇痛效果	Teng, S. L.	PDF	N/A	Nanomedicines targeting signaling of protease-activated receptor 2 in organelles provide sustained analgesia
单细胞实验的顺序设计以识别基因表达的离散随机模型。	Cook, J.	PDF	N/A	Sequential design of single-cell experiments to identify discrete stochastic models for gene expression.
揭示种族间面孔感知背后的神经表征	Shoura, M.	PDF	N/A	Revealing the neural representations underlying other-race face perception
乳腺癌中驱动下丘脑-垂体-肾上腺轴功能障碍的脑-体反馈回路	Gomez, A.	PDF	N/A	A brain-body feedback loop driving HPA-axis dysfunction in breast cancer
TAAR2-9敲除小鼠表现出觉醒度降低和快速眼动睡眠（REM睡眠）紊乱	Park, S.	PDF	N/A	TAAR2-9 Knockout Mice Exhibit Reduced Wakefulness and Disrupted REM Sleep
心脏、呼吸和胃的节律独立地调节皮层脊髓兴奋性。	Engelen, T.	PDF	N/A	The cardiac, respiratory and gastric rhythms independently modulate corticospinal excitability
Parechovirus-3感染破坏了免疫代谢，并导致神经类器官中的谷氨酸兴奋性毒性	Capendale, P. E.	PDF	N/A	Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids
过敏原免疫后，2型常规树突状细胞中的IFN-I信号支持TH2和T滤泡辅助细胞的分化。	Webb, G. R.	PDF	N/A	IFN-I signaling in type 2 conventional dendritic cells supports TH2 and T follicular helper differentiation after allergen immunization
用于性别鉴定的高保真遗传标记，适用于大麻（Cannabis sativa）幼苗的性别鉴定。	Prentout, D.	PDF	N/A	High fidelity genetic markers for sexing Cannabis sativa seedlings
布朗运动数据增强：一种提升神经网络在纳米孔传感器性能的方法	Kipen, J.	PDF	N/A	Brownian motion data augmentation: a method to push neural network performance on nanopore sensors
糖尿病视网膜病变中自噬相关基因的鉴定与验证	Peng, W.	PDF	N/A	Identification and Validation of Mitophagy-Related Genes in Diabetic Retinopathy
量子力学预测Bicoid的解读时间不到一秒。	Lone, I.	PDF	N/A	Quantum mechanics predicts Bicoid interpretation times of less than a second
血小板PI3Kβ调控乳腺癌转移	Graff, R. C.	PDF	N/A	Platelet PI3Kβ regulates breast cancer metastasis
RAD23A的减少可延长寿命并减轻TDP-43小鼠的病理症状	Xueshui, G. n.	PDF	N/A	Reduction of RAD23A extends lifespan and mitigates pathology in TDP-43 mice
去蜡人脑组织的定量细胞结构表型分析	Di Meo, D.	PDF	N/A	Quantitative cytoarchitectural phenotyping of deparaffinized human brain tissues
胆碱能反馈用于特定情境下对感觉表征的调节	Yu, B.	PDF	N/A	Cholinergic feedback for context-specific modulation of sensory representations
在观察者的大脑中：双稳态运动揭示了V1区域中尺度反馈调制的存在	Pizzuti, A.	PDF	N/A	In the brain of the beholder: bi-stable motion reveals mesoscopic-scale feedback modulation in V1
早期至中期儿童非周期性脑电活动的纵向轨迹	Sacks, D. D.	PDF	N/A	Longitudinal trajectories of aperiodic EEG activity in early to middle childhood
G-CSF和IL-6在严重病毒感染期间驱动髓系失调	Kajihara, K.	PDF	N/A	G-CSF and IL-6 drive myeloid dysregulation during severe viral infection
BRUCE肝虚证通过损害肝细胞的线粒体代谢和激活肝星状细胞中的STAT3信号，在PTEN肝虚证的背景下加剧了MASLD/MASH。	Che, L.	PDF	N/A	BRUCE liver-deficiency potentiates MASLD/MASH in PTEN liver-deficient background by impairment of mitochondrial metabolism in hepatocytes and activation of STAT3 signaling in hepatic stellate cells
中东呼吸综合征冠状病毒的持续演变，沙特阿拉伯王国，2023-2024年	Hassan, A. M.	PDF	N/A	Ongoing evolution of Middle East Respiratory Syndrome Coronavirus, Kingdom of Saudi Arabia, 2023-2024
SCAMPI：一种可扩展的统计框架，用于利用跨性状相关性进行全基因组交互测试	Bian, S.	PDF	N/A	SCAMPI: A scalable statistical framework for genome-wide interaction testing harnessing cross-trait correlations
亚细胞水平空间转录组学与PHOTON	Rajachandran, S.	PDF	N/A	Subcellular Level Spatial Transcriptomics with PHOTON
通过结合高通量筛选实验与非靶向代谢组学方法，探究美洲接骨木化合物在抗氧化、抗病毒和抗菌特性方面的潜力。	Dwikarina, A.	PDF	N/A	Exploring American Elderberry Compounds for Antioxidant, Antiviral, and Antibacterial Properties Through High-Throughput Screening Assays Combined with Untargeted Metabolomics
快速生产来自类精干细胞的改良牛羊	Yang, L.	PDF	N/A	Rapid production of modified cattle and sheep from spermatid-like stem cells
随机取向的微槽水凝胶引导细胞运动，调节运动速度，并控制细胞扩散的方向性。	Ghosh, B.	PDF	N/A	Randomly oriented microgrooved hydrogel guides cellular motility, modulates speed, and governs directionality of cellular spread
手性组氨酸富集肽凝聚体增强抗原向T细胞的递送	Pramanik, U.	PDF	N/A	Enantiomeric histidine-rich peptide coacervates enhance antigen delivery to T cells
动态关联（Associations on the Fly）是一项新功能，旨在促进对Open Targets平台证据的探索。	Cruz-Castillo, C.	PDF	N/A	Associations on the Fly, a new feature aiming to facilitate exploration of the Open Targets Platform evidence
通过局部几何生成进行三维分子预训练	Sun, Y.	PDF	N/A	3D Molecular Pretraining via Localized Geometric Generation
不同的基质细胞群定义了B细胞急性淋巴母细胞白血病的微环境	Blanco, M. N. F.	PDF	N/A	Distinct Stromal Cell Populations Define the B-cell Acute Lymphoblastic Leukemia Microenvironment
优化形状定义微粒的制备以实现持续药物递送：“少即是多”范式	Murgia, D.	PDF	N/A	Optimizing The Fabrication Of Shape-Defined Microparticles For Sustained Drug Delivery: The 'Less Is More' Paradigm
缺血再灌注后外肾髓优先损伤依赖于高氧化代谢	Arnoux, G.	PDF	N/A	The preferential injury of outer renal medulla after ischemia-reperfusion relies on high oxidative metabolism
高剂量大麻二酚预处理对抗阿片类药物引起的持续性呼吸暂停的概念验证	Wiese, B. M.	PDF	N/A	Proof of Concept for High-Dose Cannabidiol Pretreatment to Antagonize Opioid Induced Persistent Apnea
全身麻醉激活的中央杏仁核神经元在神经病理性疼痛的急性期和晚期阶段的不同作用	Zhao, J.	PDF	N/A	Distinct roles of general anesthesia activated CeA neurons in acute versus late phase of neuropathic pain
物体非刚性的各向异性：皮层各向异性的高级知觉后果	Maruya, A.	PDF	N/A	Anisotropy of object non-rigidity: High-level perceptual consequences of cortical anisotropy
致病性微生物群通过改变能量代谢破坏脑类器官的完整结构	Isik, M.	PDF	N/A	Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism
糖脂质系统对α-突触核蛋白传播的影响：水通道蛋白-4和肌营养不良蛋白相关蛋白复合物的作用	Lopes, D. M.	PDF	N/A	Influence of the Glymphatic System on α-Synuclein Propagation: Role of Aquaporin-4 and the Dystrophin-Associated Protein Complex
使用即兴演讲（IMPRO）的新压力诱发协议的有效性	Saskovets, M.	PDF	N/A	Validity of a New Stress Induction Protocol using Speech Improvisation (IMPRO)
通过脑机接口对皮层波进行操作性条件反射	Dogadov, A.	PDF	N/A	Operant conditioning of cortical waves through a brain-machine interface
PLCγ2的保护性变体通过增强有益的微胶质细胞功能，减轻了与阿尔茨海默病相关的病理。	Takalo, M.	PDF	N/A	Protective variant in PLCgamma2 mitigates Alzheimer's disease associated pathology via enhancing beneficial microglia functions
成年少突胶质细胞生成通过ADAMTS4重塑血脑屏障来调控弓状核神经元的葡萄糖感应	Buller, S.	PDF	N/A	Adult oligodendrogenesis gates arcuate neuronal glucose sensing through remodelling of the blood-hypothalamus barrier via ADAMTS4
胰岛淀粉样蛋白破坏MHC II类抗原呈递，并保护NOD小鼠免受自身免疫性糖尿病的影响。	Denroche, H. C.	PDF	N/A	Islet amyloid disrupts MHC Class II antigen presentation and protects NOD mice from autoimmune diabetes.
单细胞和时空转录组分析揭示委内瑞拉马脑炎病毒感染后脑部免疫浸润情况	Rangel, M.	PDF	N/A	Single-cell and spatiotemporal transcriptomic profiling of brain immune infiltration following Venezuelan equine encephalitis virus infection
SARS-CoV-2蛋白ORF3a诱导溶酶体膜的Atg8化	Ajnar, D.	PDF	N/A	SARS-CoV-2 protein ORF3a induces Atg8ylation of lysosomal membranes
利用相关性和机制性物种分布模型预测当前和未来环境及气候变化下的虫媒疾病风险：以英国西尼罗河病毒为例的研究。	Withers, A. J.	PDF	N/A	Using correlative and mechanistic species distribution models to predict vector-borne disease risk for the current and future environmental and climatic change: a case study of West Nile Virus in the UK.
评估高致病性禽流感H5病毒在法国肉鸡和蛋鸡生产网络中传播的风险	Hautefeuille, C.	PDF	N/A	Assessing the risk of highly pathogenic avian influenza H5 viruses spread within French broiler and layer production networks
苔藓藻基因组：绿色植物多细胞化和陆地化的替代机制	Caisova, L.	PDF	N/A	The Draparnaldia genome: alternative mechanisms for multicellularity and terrestrialization in green plants
EBAX-1/ZSWIM8 破坏 miRNA，导致捕食特征的跨代记忆	Quiobe, S. P.	PDF	N/A	EBAX-1/ZSWIM8 destabilizes miRNAs resulting in transgenerational memory of a predatory trait
长链非编码RNA TAAL是糖尿病视网膜病变中Tie1介导的血管功能的调节因子	Ranjan, G.	PDF	N/A	LncRNA TAAL is a Modulator of Tie1-Mediated Vascular Function in Diabetic Retinopathy
单倍型解析的基因组组装为新疆最古老的葡萄品种（木纳格）的基因组构成提供了深入见解。	Zhong, H.	PDF	N/A	Haplotype-resolved assemblies provide insights into genomic makeup of the oldest grapevine cultivar (Munage) in Xingjiang
DiatOmicBase是一个以基因为中心的平台，用于挖掘硅藻基因组间的功能组学数据。	Villar, E.	PDF	N/A	DiatOmicBase, a gene-centered platform to mine functional omics data across diatom genomes
内皮糖萼的成熟度水平调节其与带电纳米材料的相互作用	Bridges, C.	PDF	N/A	The level of endothelial glycocalyx maturity modulates interactions with charged nano-materials
蛋白质冠组成因果分析：磷脂酰胆碱通过蛋白质组学增强血浆蛋白质组谱分析	Rafieioskouei, A.	PDF	N/A	Causality Analysis of Protein Corona Composition: Phosphatidylcholine-Enhances Plasma Proteome Profiling by Proteomics
ScReNI：通过整合scRNA-seq和scATAC-seq数据进行单细胞调控网络推断	Xu, X.	PDF	N/A	ScReNI: single-cell regulatory network inference through integrating scRNA-seq and scATAC-seq data
LoVis4u：用于比较基因组的位点可视化工具	Egorov, A. A.	PDF	N/A	LoVis4u: Locus Visualisation tool for comparative genomics
SVbyEye：一种用于描述全基因组组装间结构变异的视觉工具	Porubsky, D.	PDF	N/A	SVbyEye: A visual tool to characterize structural variation among whole genome assemblies
一种高通量表型筛选结合基于超大规模深度学习的虚拟筛选揭示了新型抗菌化合物骨架	Scalia, G.	PDF	N/A	A high-throughput phenotypic screen combined with an ultra-large-scale deep learning-based virtual screening reveals novel scaffolds of antibacterial compounds
考古记录中β-乳球蛋白肽的存续性：脆弱性与序列变异	Fonseca, B.	PDF	N/A	The Survival of β-lactoglobulin Peptides in the Archaeological Record: Vulnerability vs. Sequence Variation
光惰性气体对脂质过氧化引起的化学发光可能的作用机制	Oliynyk, I.	PDF	N/A	Possible Mechanisms Of Action Of Light Inert Gases On Chemiluminescence Arising As A Result Of Lipid Peroxidation
BST2在癌症进展过程中诱导血管平滑肌细胞的可塑性和表型转换	Bell, C.	PDF	N/A	BST2 induces vascular smooth muscle cell plasticity and phenotype switching during cancer progression
癌症适应性治疗周期设计与稳定性：确定性与随机性模型	Vilela, Y. G.	PDF	N/A	On the design and stability of cancer adaptive therapy cycles: deterministic and stochastic models
骨髓中的转移性肿瘤细胞与配对的神经母细胞瘤肿瘤不同，并包含具有治疗抵抗特性的亚群。	Hochheuser, C.	PDF	N/A	Metastatic tumor cells in bone marrow differ from paired neuroblastoma tumor and contain subsets with therapy-resistant characteristics
使用深度学习从静息状态功能连接预测任务激活图	Madsen, S. J.	PDF	N/A	Predicting Task Activation Maps from Resting-State Functional Connectivity using Deep Learning
增强初级视觉皮层与身体选择性皮层之间的前向连接，减少任务无关维度对身体判断的干扰	Gandolfo, M.	PDF	N/A	Boosting forward connectivity between primary visual and body selective cortex reduces interference of task irrelevant dimensions on body judgements
ARHGEF3调控毛囊形态发生	Laurin, M.	PDF	N/A	ARHGEF3 Regulates Hair Follicle Morphogenesis
有益根际细菌和病毒感染调节大豆代谢组，并影响病毒媒介Epilachna varivestis的取食偏好。	Pulido, H.	PDF	N/A	Beneficial rhizobacteria and virus infection modulate the soybean metabolome and influence the feeding preferences of the virus vector Epilachna varivestis.
足部放置控制在跨物种的稳定运动中起着基础作用	De Comite, A.	PDF	N/A	Foot placement control underlies stable locomotion across species
评估携带SUB1和DRO1基因的IR64水稻近等基因系对逆境的耐受性	Sakagami, J.-I.	PDF	N/A	Evaluation of stress tolerance in IR64 rice near-isogenic lines carrying SUB1 and DRO1 genes
对英国市场上销售的基于植物和肉类成分的完整干狗粮的营养分析	Brociek, R. A.	PDF	N/A	Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK
促炎介质使小鼠感觉神经元中的瞬时受体电位梅拉司林3型阳离子通道（TRPM3）信号传导敏感化	Aguilera-Lizarraga, J.	PDF	N/A	Pro-inflammatory mediators sensitise Transient Receptor Potential Melastatin 3 cation channel (TRPM3) signalling in mouse sensory neurons
脊髓感觉运动回路在侧胸半横断后控制系带和分带步态相位持续时间的操作	Rybak, I. A.	PDF	N/A	Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection
土壤氧化还原作用驱动病毒-宿主群落动态及热带雨林土壤中植物生物量的降解	Trubl, G.	PDF	N/A	Soil redox drives virus-host community dynamics and plant biomass degradation in tropical rainforest soils
海洋酵母对基于昆布多糖的基质的利用和降解表明它们在微生物循环动力学中具有生态位特异性作用。	Reich, M.	PDF	N/A	Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics.
表面介导的噬菌体防御对细菌间拮抗作用产生了适应性权衡	Tsai, C.-E.	PDF	N/A	Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism
tRNA赖氨酰化对于恶性疟原虫顶质体中发现的最低翻译系统至关重要。	Elahi, R.	PDF	N/A	tRNA lysidinylation is essential for the minimal translation system found in the apicoplast of Plasmodium falciparum
计算机分析显示，常用的PCR检测方法对肠道病毒物种的靶向性存在差异。	Trinh, V. N.	PDF	N/A	In silico analysis reveals differential targeting of enterovirus species by commonly used PCR assays
应激诱导小蛋白的翻译谱分析揭示了不同信号系统之间意想不到的联系	Vellappan, S.	PDF	N/A	Translational profiling of stress-induced small proteins uncovers an unexpected connection among distinct signaling systems
新加坡受试者粪便样本中分离的三种Acutalibacteraceae细菌的基因组重建与饮食反应评估。	Park, M. A.	PDF	N/A	Genomic Reconstruction and Dietary Response Assessment of Three Acutalibacteraceae Bacteria Isolated from Fecal Samples of Singapore Subjects.
利用膜编辑结合邻近标记技术揭示的调控磷脂酸稳态的动态网络	Tei, R.	PDF	N/A	Dynamic network regulating phosphatidic acid homeostasis revealed using membrane editing coupled to proximity labeling
Nf1对睡眠行为的影响是通过SARM1依赖的NAD+代谢缺陷引起的饥饿所介导的。	Sofela, F. A.	PDF	N/A	Effects of Nf1 on sleep behavior are mediated through starvation caused by deficits in SARM1 dependent NAD+ metabolism.
解释预测区间和分布以解码元分析中的生物普遍性	Yang, Y.	PDF	N/A	Interpreting prediction intervals and distributions for decoding biological generality in meta-analyses
通过结肠发酵和小麦阿拉伯木聚糖的酶催化产生生物活性结构基序：体外、计算机模拟和功能分析提供的与Toll样受体相互作用的证据	Guerreiro, C. d. A.	PDF	N/A	Production of bioactive structural motifs from wheat arabinoxylan via colonic fermentation and enzymatic catalysis: evidence of interaction with toll-like receptors from in vitro, in silico and functional analysis
鞘氨醇激酶1在脂肪来源干细胞中被糖皮质激素诱导，并增强糖皮质激素介导的脂肪扩张信号传导。	Lambert, J. M.	PDF	N/A	Sphingosine kinase 1 is induced by glucocorticoids in adipose derived stem cells and enhances glucocorticoid mediated signaling in adipose expansion.
线粒体脂肪酸氧化受红光照射刺激	Herrera, M. A.	PDF	N/A	Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation
异常剪接体中间体在其解体过程中的结构	Soni, K.	PDF	N/A	Structures of aberrant spliceosome intermediates on their way to disassembly
机器学习增强的分子动力学模拟（MD）揭示了ZTPriboswitch配体的亲和力与激活之间的脱节现象。	Fullenkamp, C. R.	PDF	N/A	Machine learning-augmented molecular dynamics simulations (MD) reveal insights into the disconnect between affinity and activation of ZTPriboswitch ligands
质子化/去质子化驱动的低电位铁氧还蛋白氧化还原稳定性的开关	Wada, K.	PDF	N/A	Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin
分子转子为α-突触核蛋白聚集物的形成和转化机制提供了深入见解。	Allerton, S. C.	PDF	N/A	Molecular rotors provide insight into the mechanism of formation and conversion of α-synuclein aggregates
一种针对糖体膜生物合成的抑制剂可杀死利什曼原虫寄生虫。	Chou, S.-E.	PDF	N/A	An inhibitor targeting glycosome membrane biogenesis kills Leishmania parasites
AI生成的小型活页夹提升了主要编辑效果	Park, J.-C.	PDF	N/A	AI-generated small binder improves prime editing
仿生病毒样颗粒调控细胞功能	Maayouf, H.	PDF	N/A	Biomimetic Virus-Like Particles to control cell functions
计算机模拟研究：选择性生物碱作为阿尔茨海默病β和γ-分泌酶双重抑制剂	Onifade, I.	PDF	N/A	In silico study of selected alkaloids as dual inhibitors of β and γ-Secretases for Alzheimer's disease
映射和建模内在神经时间尺度的年龄相关变化	Wu, K.	PDF	N/A	Mapping and Modeling Age-Related Changes in Intrinsic Neural Timescales
利用预训练的深度蛋白质语言模型预测肽段的碰撞截面	Nakai-Kasai, A.	PDF	N/A	Leveraging Pretrained Deep Protein Language Model to Predict Peptide Collision Cross Section
极端嗜热、分解木质纤维素的厌氧细菌Anaerocellum bescii（前称Caldicellulosiruptor bescii）中的麦芽糊精转运	Tjo, H.	PDF	N/A	Maltodextrin Transport in the Extremely Thermophilic, Lignocellulose Degrading Bacterium Anaerocellum bescii (f. Caldicellulosiruptor bescii)
振动触觉耳迷走神经刺激在人类中改变边缘系统连接：一项初步研究	Donovan, K. M.	PDF	N/A	Vibrotactile auricular vagus nerve stimulation alters limbic system connectivity in humans: A pilot study
# BioRxiv 2024-09-13 Papers

标题	作者	PDF链接	代码仓库	Title
大脑状态和皮层层特异性机制在感知阈值下的作用	Morton, M. P.	PDF	N/A	Brain state and cortical layer-specific mechanisms underlying perception at threshold
跨多个脓肿分枝杆菌分离株的转座子测序揭示了菌株间显著的功能基因组多样性	Akusobi, C.	PDF	N/A	Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains
Kisspeptin纤维及其受体分布分析表明其在中枢感觉处理和行为状态控制中可能发挥的作用。	Zhang, L.	PDF	N/A	Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
核篮蛋白调控芽殖酵母中核孔复合体的分布和移动性	Zsok, J.	PDF	N/A	Nuclear basket proteins regulate the distribution and mobility of nuclear pore complexes in budding yeast
呼吸与觉醒之间的动态联系	Kluger, D. S.	PDF	N/A	A dynamic link between respiration and arousal
Hill型方程揭示了由p53脉冲引导的目标蛋白质表达的调控原理。	Shi, X.	PDF	N/A	The Hill-type equation reveals the regulatory principle of target protein expression led by p53 pulsing
伏隔核多巴胺释放反映了工具性学习过程中的贝叶斯推理	Qu, A. J.	PDF	N/A	Nucleus accumbens dopamine release reflects Bayesian inference during instrumental learning
在转移性微环境中异常激活的伤口愈合程序促进了骨肉瘤细胞在肺部的定植。	Reinecke, J. B.	PDF	N/A	Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells
高参数蛋白图谱揭示了早期发育中人类肺的空间组织结构	Sariyar, S.	PDF	N/A	High-parametric protein maps reveal the spatial organization in early-developing human lung
WildPose：一种长距离3D野生动物运动捕捉系统	Muramatsu, N.	PDF	N/A	WildPose: A Long-Range 3D wildlife motion capture system
直接耦合分析与注意力机制	Caredda, F.	PDF	N/A	Direct Coupling Analysis and The Attention Mechanism
开发用于研究合作行为的自动化拉取装置（MarmoAAP）	Meisner, O. C.	PDF	N/A	Development of a Marmoset Apparatus for Automated Pulling (MarmoAAP) to Study Cooperative Behaviors
CD44促进了在空气介导的细胞间信号传导中的粘附相互作用。	Bowman, R. L.	PDF	N/A	CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling
小鼠胚胎发育过程中多条件和多模态时间剖面推断	Zhang, R.	PDF	N/A	Multi-condition and multi-modal temporal profile inference during mouse embryonic development
Vps5-Vps17 SNX-BAR蛋白与Retromer组装的分子基础	Chen, K.-E.	PDF	N/A	Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
moPepGen：快速全面鉴定非规范肽段	Zhu, C.	PDF	N/A	moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides
理解先前经验对疼痛感知和神经性疼痛影响的计算框架	Ramne, M.	PDF	N/A	A Computational Framework for Understanding the Impact of Prior Experiences on Pain Perception and Neuropathic Pain
通过微调扩散模型精确生成固有无序蛋白质的构象集合	Zhu, J.	PDF	N/A	Precise Generation of Conformational Ensembles for Intrinsically Disordered Proteins via Fine-tuned Diffusion Models
96孔聚丙烯酰胺凝胶用于电泳和Western印迹	Birtwistle, M. R.	PDF	N/A	A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting
性别分化与性二态性的共同演化	Lesaffre, T.	PDF	N/A	The joint evolution of separate sexes and sexual dimorphism
揭示基因组复杂性：基因组图结构分析与优化变异检测工作流程的框架	Kamaraj, V.	PDF	N/A	Unveiling Genomic Complexity: A Framework for Genome Graph Structural Analysis and Optimised Variant Calling Workflows
果蝇神经肌肉接头处的外周胶质细胞和神经元共同调节活动诱导的突触重塑	Chang, Y.-C.	PDF	N/A	Peripheral glia and neurons jointly regulate activity-induced synaptic remodeling at the Drosophila neuromuscular junction
微生物代谢物引导的CAR T细胞工程通过表观遗传-代谢交叉对话增强抗肿瘤免疫	Staudt, S.	PDF	N/A	Microbial metabolite-guided CAR T cell engineering enhances anti-tumor immunity via epigenetic-metabolic crosstalk
综合多模型分析肠道炎症揭示了临床前和临床炎症性肠病的关键分子特征	Gonzalez Acera, M.	PDF	N/A	Integrated multi-model analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD
训练在动物园中对声音学习实验缺乏经验的港海豹参与发声学习实验	Duengen, D.	PDF	N/A	Training Experimentally Naive Harbor Seals to Participate in Vocal Learning Experiments in a Zoo
编排不可能的化学：B12依赖型甲硫氨酸合成酶催化编排的结构快照	Mendoza, J.	PDF	N/A	Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography
胆碱能信号通过不同方式调节鸣禽的鸣唱前运动回路，以稳定鸣唱。	Xu, N.	PDF	N/A	Cholinergic signaling differentially regulates song premotor circuits to stabilize songs in songbirds
IL-6和IL-27负向调控与淋巴驱动性滑膜炎相关的CRTAM表达CD4+ T细胞。	Derrac Soria, A.	PDF	N/A	IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.
人类和蝙蝠基因组在COSMIC突变特征下的稳健性	Song, J.-H.	PDF	N/A	Human and bats genome robustness under COSMIC mutational signatures
通过拓扑约束分子生成模型发现新型喹啉类木瓜蛋白酶样蛋白酶抑制剂用于COVID-19	Shang, J.	PDF	N/A	Discovery of novel quinoline papain-like protease inhibitors for COVID-19 through topology constrained molecular generative model
HIV Vpr激活了一种核仁特异性的ATR通路，以降解核仁应激传感器CCDC137	Nisson, K. A.	PDF	N/A	HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137
解锁隐藏噬菌体多样性，以完成BASEL收藏，系统探索噬菌体-宿主相互作用	Humolli, D.	PDF	N/A	Unlocking hidden phage diversity to complete the BASEL collection for systematic exploration of phage-host interactions
炎症通过重塑骨髓微环境中的特定区域来干扰造血功能。	Swann, J. W.	PDF	N/A	Inflammation perturbs hematopoiesis by remodeling specific compartments of the bone marrow niche
单层和双层中脂质动力学精确建模的挑战	Tempra, C.	PDF	N/A	Challenges in the Accurate Modelling of Lipid Dynamics in Monolayers and Bilayers
ADPKD 变异体在 PKD2 孔螺旋中导致门结构塌陷和不同形式的通道功能障碍。	Palomero, O. E.	PDF	N/A	ADPKD variants in the PKD2 pore helix cause structural collapse of the gate and distinct forms of channel dysfunction.
综合分子动力学模拟解析交联数据，揭示线粒体蛋白质分布	Schuhmann, F.	PDF	N/A	Integrative Molecular Dynamics Simulations Untangle Cross-Linking Data to Unveil Mitochondrial Protein Distributions
G3BP1通过负调控MYD88-ARNO-ARF6信号通路维持血管内皮屏障的完整性。	Wen, B.	PDF	N/A	G3BP1 Maintains Vascular Endothelial Barrier Integrity by Negatively Regulating the MYD88-ARNO-ARF6 Signaling Pathway
生长素高亮荧光的发展	Aoyama, T.	PDF	N/A	Development of bright fluorescent auxin
HCV感染中病毒适应性和适应性免疫反应的时间动态	Walker, M. R.	PDF	N/A	Temporal dynamics of viral fitness and the adaptive immune response in HCV infection
系统综述与荟萃分析：欧盟地区Hyalomma marginatum蜱的脊椎动物宿主	Bah, M. T.	PDF	N/A	Systematic review and meta-analysis of Hyalomma marginatum vertebrate hosts in the EU
欺凌与早期大脑发育：一项从青少年到成年早期的纵向结构磁共振成像研究	Connaughton, M.	PDF	N/A	Bullying and Early Brain Development: A Longitudinal Structural Magnetic Resonance Imaging Study from Adolescence to Early Adulthood
阴道微生物群作为早产预测指标：一项观察性队列研究	Lesimple, L.	PDF	N/A	Vaginal microbiota as a predictor of preterm birth: an observational cohort study
针对牛繁殖失败相关病原体的靶向综合下一代测序面板，实现病原体的同步检测	Periyasamy, D.	PDF	N/A	Targeted syndromic next-generation sequencing panel for simultaneous detection of pathogens associated with bovine reproductive failure
不同用途温带玉米杂交种在不同环境下的核权重和源/汇比确定	Chazarreta, Y. D.	PDF	N/A	Kernel weight and source/sink ratio determination of temperate maize hybrids with different end uses under contrasting environments
念珠菌（Candida albicans）与粪肠球菌（Enterococcus faecalis）之间的跨物种协同宿主细胞损伤	Kapitan, M.	PDF	N/A	Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis
在pre-mRNA的3'-非翻译区，剪接位点的异质性调控基因表达	Shaji, F.	PDF	N/A	Cleavage site heterogeneity at the pre-mRNA 3'-untranslated region regulates gene expression
巨噬细胞衍生的RNAseT2通过SLK/N-WASP/肌动蛋白束促进肌肉干细胞融合	Weiss-Gayet, M.	PDF	N/A	Macrophage-derived RNAseT2 stimulates muscle stem cell fusion via SLK/N-WASP/actin bundling
连接组上的扩散小波：利用图扩散小波定位介导结构-功能映射的扩散源	Jain, C. S.	PDF	N/A	Diffusion Wavelets on Connectome: Localizing the Sources of Diffusion Mediating Structure-Function Mapping Using Graph Diffusion Wavelets
DRED：一个综合性的与重复扩展疾病相关的基因数据库	Shi, Q.	PDF	N/A	DRED: A Comprehensive Database of Genes Related to Repeat Expansion Diseases
肝细胞中的胰高血糖素受体（GCGR）对于结构上与双重GCGR/GLP1R激动剂survodutide相关的类似物在体重减轻方面的卓越效果是必需的。	Long, F.	PDF	N/A	Hepatic GCGR is required for the superior weight loss effects of a structurally related analogue of the dual GCGR/GLP1R agonist survodutide
受控检索依赖于语义控制区域与视觉皮层之间的定向交互作用：来自振荡动力学的MEG证据	Eisenhauer, S.	PDF	N/A	Controlled retrieval relies on directed interactions between semantic control regions and visual cortex: MEG evidence from oscillatory dynamics
肩胛间棕色脂肪组织的交感神经支配并非雄性饮食诱导肥胖大鼠中OT引发体重增加和脂肪减少的主要介质。	Edwards, M. M.	PDF	N/A	Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
RBBP5通过表观遗传调控全局蛋白质稳态动力学，确保哺乳动物机体健康	Kubra, S.	PDF	N/A	Epigenetic regulation of global proteostasis dynamics by RBBP5 ensures mammalian organismal health
高尔基体相关微管交联蛋白MTCL2促进小脑颗粒神经元树突的多极延伸。	Minekawa, M.	PDF	N/A	The Golgi-associated microtubule cross-linking protein MTCL2 promotes the multipolar extension of dendrites in cerebellar granule neurons.
细胞质中的核糖体搭乘线粒体前往树突	Renken, C. J.	PDF	N/A	Cytoplasmic ribosomes hitchhike on mitochondria to dendrites
早期将初级肌管与次级肌管及成体肌肉干细胞分隔开来。	Toulouse, G.	PDF	N/A	Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells.
水牛在发情期和间情期之间无细胞唾液miRNA谱的比较	CHANDEL, R.	PDF	N/A	Comparative cell free salivary miRNA profile in Bubalus bubalis between diestrus and estrus stages
对野化与本地捕食者组合的增补、可替代及拮抗性猎物反应	St. Juliana, J. R.	PDF	N/A	Additive, substitutable, and antagonistic prey responses to feral and native predator combinations
一种通过计算指导的方法来提高VHH结合剂的表达	OZDEMIR, E. S.	PDF	N/A	A computationally guided approach to improve expression of VHH binders
具有可逆热离子交联的3D水凝胶功能性人唾液腺泡细胞球状体的扩展	Munguia-Lopez, J. G.	PDF	N/A	Expansion of functional human salivary acinar cell spheroids with reversible thermo-ionically crosslinked 3D hydrogels
染色质三色单分子定位显微镜	Acosta, N.	PDF	N/A	Three-color single-molecule localization microscopy in chromatin
EmbSAM：用于快速发育胚胎图像的细胞边界定位与分割任意模型	Zhao, C.	PDF	N/A	EmbSAM: Cell boundary localization and Segment Anything Model for fast images of developing embryos
CNValidatron，利用计算机视觉实现CNV调用的自动化验证	Montalbano, S.	PDF	N/A	CNValidatron, automated validation of CNV calls using computer vision
bayesReact：表达耦合的调控基序分析在癌症和单细胞水平检测微RNA活性	Rasmussen, A. M.	PDF	N/A	bayesReact: Expression-coupled regulatory motif analysis detects microRNA activity in cancer and at the single cell level
niiv: 快速自监督神经隐式各向同性体积重建	Troidl, J.	PDF	N/A	niiv: Fast Self-supervised Neural ImplicitIsotropic Volume Reconstruction
从谱系追踪数据推断细胞分化图谱	Sashittal, P.	PDF	N/A	Inferring cell differentiation maps from lineage tracing data
Montijano-Bergues-Bory-Gompertz随机模型中未受干扰肿瘤生长的参数估计	Bonilla-Capilla, B.	PDF	N/A	Parameter estimation in the Montijano-Bergues-Bory-Gompertz stochastic model for unperturbed tumor growth
白血病衍生的apelin选择内皮龛克隆以促进肿瘤发生	Baron, C. S.	PDF	N/A	Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis
PROX1对细胞命运可塑性的主动抑制保障了肝细胞的特性，并防止了肝癌的发生。	Lim, B.	PDF	N/A	Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumourigenesis
顺序使用ATR和PARP抑制剂克服胰腺导管腺癌中获得的DNA损伤剂抗性	Herbert, K. J.	PDF	N/A	Sequential ATR and PARP Inhibition Overcomes Acquired DNA Damaging Agent Resistance in Pancreatic Ductal Adenocarcinoma
GCN2在整合应激反应之外的作用：防止过度核糖体生物合成和mRNA翻译	Roman-Trufero, M.	PDF	N/A	An integrated stress response-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation
线粒体代谢是结直肠癌化疗敏感性的关键决定因素	Moss, D. Y.	PDF	N/A	Mitochondrial metabolism is a key determinant of chemotherapy sensitivity in Colorectal Cancer
梅克尔细胞癌衍生的巨噬细胞迁移抑制因子（MIF）可能促进慢性淋巴细胞白血病的持续存在。	Alencar, G. F.	PDF	N/A	Merkel cell carcinoma-derived macrophage migration inhibitory factor (MIF) may promote persistence of Chronic Lymphocytic Leukemia
进化获得了一种原始的光依赖性核重定位现象，这种现象在地钱（Marchantia polymorpha）中被观察到。	Iwabuchi, K.	PDF	N/A	Evolutionary acquisition of a primitive light-dependent nuclear relocation in Marchantia polymorpha
抗体亲和力的提高及利用PURE核糖体展示和微生物分泌系统	Kihara, M.	PDF	N/A	Improvement of Antibody Affinity and Using PURE Ribosome Display and Microbial Secretion System
RoCi - 基于滚环复制的单步多拷贝整合系统	Antsotegi-Uskola, M.	PDF	N/A	RoCi - A Single Step Multi-Copy Integration System Based on Rolling-Circle Replication
基于BEN的预测建模（BPM）进行表型预测	Song, D.	PDF	N/A	Phenotype Prediction Using BEN-Based Predictive Modeling (BPM)
斑马鱼幼体感觉运动反应的发育：野生型与GCaMP6s转基因品系的比较	Caperaa, M.	PDF	N/A	Development of sensorimotor responses in larval zebrafish: a comparison between wild-type and GCaMP6s transgenic line
利用结构方程模型预测静态和动态听觉图形-背景分析中的噪音中言语能力	Guo, X.	PDF	N/A	Predicting speech-in-noise ability with static and dynamic auditory figure-ground analysis using structural equation modelling
灵长类上丘对暗对比的微扫视前敏感性增强更强	Wu, W.	PDF	N/A	Stronger premicrosaccadic sensitivity enhancement for dark contrasts in the primate superior colliculus
PSEN1突变通过破坏受调控的细胞内蛋白水解作用，使家族性阿尔茨海默病中的星形胶质细胞模型易发炎症。	Ziff, O. J.	PDF	N/A	Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis
在海马体循环网络模型中，条形码活动能够实现高效的记忆绑定。	Fang, C.	PDF	N/A	Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding
M3毒蕈碱乙酰胆碱受体对人类记忆辅助性T细胞炎症特征的调节作用	Gholizadeh, F.	PDF	N/A	Modulatory Effects of M3 Muscarinic Acetylcholine Receptor on Inflammatory Profiles of Human Memory T Helper Cells
非经典白介素-22受体信号在真菌免疫监视期间重塑黏膜屏障	Millet, N.	PDF	N/A	Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance
枯萎的野花和沮丧的蜜蜂：气候变化威胁美国州象征	Ge, X.	PDF	N/A	Wilting Wildflowers and Bummed-Out Bees: Climate Change Threatens U.S. State Symbols
在多菌株接种中，苜蓿共生基因的突变为根瘤菌中自然发生的遗传变异创造了复杂的选择环境。	Guha, S.	PDF	N/A	In multi-strain inoculations, mutation of Medicago symbiosis genes creates a complex selective landscape for naturally-occurring genetic variation in rhizobia
注意极地太阳：尽管空气温度相对较低，太阳辐射仍频繁引发繁殖中的王企鹅的热应激。	Noiret, A.	PDF	N/A	Mind the polar sun: Solar radiations trigger frequent heat stress in breeding king penguins, despite relatively cool air temperatures.
胰腺疾病风险相关增强子的预测优先级	Wang, L.	PDF	N/A	Predictive Prioritization of Enhancers Associated with Pancreas Disease Risk
一种占卜鼠尾草（Salvia divinorum）的染色体级别参考基因组为萨维诺林A的生物合成提供了深入见解。	Ford, S. A.	PDF	N/A	A chromosome level reference genome of Diviners sage (Salvia divinorum) provides insight into salvinorin A biosynthesis
手势交流的特异性：巴巴利猕猴（Macaca sylvanus）拍手行为的个案研究	Bosshard, T. C.	PDF	N/A	Idiosyncrasy in gestural communication: a case study of hand-clapping in a Barbary macaque (Macaca sylvanus)
尼古丁与阿尔法辐射诱导的DNA损伤相互作用，这可能有助于在人类肺上皮细胞中进行错误的修复。	Boroumand, N.	PDF	N/A	Nicotine interacts with DNA lesions induced by alpha radiation which may contribute to erroneous repair in human lung epithelial cells
喷墨打印的石墨烯多电极阵列：一种适用于体外心脏电生理学的可及平台	Lumpuy-Castillo, J.	PDF	N/A	Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology
Novae：一种基于图的空间转录组学数据基础模型	Blampey, Q.	PDF	N/A	Novae: a graph-based foundation model for spatial transcriptomics data
基于系统发育的代表性变异体选择与Navargator：使用两个免疫研究中的体液交叉反应数据验证原理	Curran, D. M.	PDF	N/A	Phylogeny-based selection of representative variants with Navargator: Proof of principle using humoral cross-reactivity data from two immunization studies
G2PDeep-v2：一种基于网络的深度学习框架，用于利用多组学数据进行表型预测和生物标志物发现	Zeng, S.	PDF	N/A	G2PDeep-v2: a web-based deep-learning framework for phenotype prediction and biomarker discovery using multi-omics data
BEGAN：基于玻尔兹曼加权数据增强的增强型GAN用于昆虫信息素受体中的分子设计	Dai, J.	PDF	N/A	BEGAN: Boltzmann-Reweighted Data Augmentation for Enhanced GAN-Based Molecule Design in Insect Pheromone Receptors
Pyjacker识别出急性髓系白血病中的增强子劫持事件，包括通过删除7q激活MNX1。	Sollier, E.	PDF	N/A	Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q
DNA损伤应答缺陷增强神经母细胞瘤进展并提高对PARP和ATR联合抑制的敏感性	Hayes, M. N.	PDF	N/A	DNA Damage Response Deficiency Enhances Neuroblastoma Progression and Sensitivity to Combination PARP and ATR Inhibition
高效发现非底物型共价抑制剂及其与S-腺苷甲硫氨酸脱羧酶的结构-活性关系分析	Ai, Y.	PDF	N/A	High-efficiency discovery and structure-activity-relationship analysis of non-substrate-based covalent inhibitors of S-adenosylmethionine decarboxylase
小鼠远端输卵管中多纤毛细胞的与衰老相关的空泡化反映了独特的细胞身份和管腔微环境。	Harwalkar, K.	PDF	N/A	Aging-associated vacuolation of multi-ciliated cells in the distal mouse oviduct reflects unique cell identity and luminal microenvironment
霜霉病菌效应蛋白HaRxL106与转录因子BIM1相互作用，改变植物生长、油菜素内酯信号传导及对病原体的易感性。	Bogino, M. F.	PDF	N/A	Downy mildew effector HaRxL106 interacts with the transcription factor BIM1 altering plant growth, BR signaling and susceptibility to pathogens
拟南芥组蛋白H3K4me3结合的ALFIN样蛋白介导组蛋白H2A的泛素化，并协调多种染色质修饰。	Su, X.-M.	PDF	N/A	The Arabidopsis histone H3K4me3-binding ALFIN-like proteins mediate histone H2A ubiquitination and coordinate diverse chromatin modifications
利用大型语言模型进行代谢工程设计	Li, X.	PDF	N/A	Leveraging large language models for metabolic engineering design
鱼类中的微量元素：生物累积评估及其相关健康风险。	Naz, S.	PDF	N/A	Trace Elements in Fish: Assessment of bioaccumulation and associated health risks.
禁食对热应激肉鸡的影响：第一部分——生长性能、肉质、肠道组织形态学和微生物反应	Ahmed, T.	PDF	N/A	Effects of fasting on heat-stressed broiler chickens: part I- growth performance, meat quality, gut histomorphological and microbial responses
神经营养因子artemin及其受体GFRα3通过离子通道TRPM8介导偏头痛样疼痛。	Yang, C.	PDF	N/A	The neurotrophin artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8
情境性恐惧表达的性别差异与内侧前额叶皮层活动的改变有关	Vazquez, K.	PDF	N/A	Sex differences in contextual fear expression are associated with altered medial prefrontal cortex activity
背侧下丘中听觉空间的人口编码在双耳线索改变的情况下仍然存在	Rogalla, M. M.	PDF	N/A	Population coding of auditory space in the dorsal inferior colliculus persists with altered binaural cues
多种感觉剥夺对内侧内嗅皮层空间编码细胞的不同影响	Tian, J.	PDF	N/A	Differential Impact of Multiple Sensory Deprivation on Spatial-coding Cells in Medial Entorhinal Cortex
爆裂放电通过电感觉神经群体优化了自然通信信号的不变编码	Metzen, M. G.	PDF	N/A	Burst firing optimizes invariant coding of natural communication signals by electrosensory neural populations
针对α-突触核蛋白的病毒编码单链抗体片段可保护小鼠免受突触核蛋白病模型中的运动障碍和神经病理学损害	Castonguay, A.-M.	PDF	N/A	Virally encoded single-chain antibody fragments targeting alpha-synuclein protect against motor impairments and neuropathology in a mouse model of synucleinopathy
IL-1b介导的角膜上皮细胞免疫代谢适应	Sanches, J. M.	PDF	N/A	IL-1b-mediated Immunometabolic Adaptation in Corneal Epithelial Cells
脑膜炎球菌疫苗Bexsero能引发强大的细胞免疫反应，这种反应针对的是但并不总是能保护小鼠在阴道感染期间免受淋病奈瑟菌的侵害。	Zeppa, J. J.	PDF	N/A	Meningococcal vaccine Bexsero elicits a robust cellular immune response that targets but is not consistently protective against Neisseria gonorrhoeae during murine vaginal infection
IFT和BBSome蛋白对于墨西哥利什曼原虫的致病性是必需的，但鞭毛运动是非必需的。	Beneke, T.	PDF	N/A	IFT and BBSome proteins are required for Leishmania mexicana pathogenicity, but flagellar motility is dispensable
对小农户水稻种植者的成本效益分析显示，现有的施肥方式严重损害了他们的收入。	Chen, J.	PDF	N/A	Cost-benefit analysis across smallholder rice farmers reveals that existing fertilization practices severely compromise their income
化石多样化速率的表观时间缩放是由采样偏差引起的。	Reijenga, B. R.	PDF	N/A	Apparent timescaling of fossil diversification rates is caused by sampling bias
洞穴作为物种泵：关键创新、隔离与周期性基因渗入驱动动态喀斯特景观中世界最大洞穴鱼辐射	Mao, T.	PDF	N/A	Caves as species pumps: key innovations, isolation, and periodic introgression drive the world's largest cavefish radiation in a dynamic karstic landscape
一种新生F-box基因通过选择性降解磷酸葡萄糖变位酶阻断种间杂交中的基因流动	Xie, D.	PDF	N/A	A Newborn F-box Gene Blocks Gene Flow by Selectively Degrading Phosphoglucomutase in Species Hybrids
强选择，但低重复性：温度对适应性基因组预测的特定影响	Rego, A.	PDF	N/A	Strong Selection, but low repeatability: Temperature-specific effects on genomic predictions of adaptation
性染色体上癌症基因的体细胞进化	Marco, A.	PDF	N/A	Somatic evolution of cancer genes in sex chromosomes
单倍体型解析基因组为研究双壳类基因组多样性的起源和功能提供了见解	Liu, S.	PDF	N/A	Haplotype-resolved genomes provide insights into the origin and function of genome diversity in bivalves
METTL3通过Akt/mTOR通路调节辐射诱导的心脏纤维化	Gu, X.-s.	PDF	N/A	METTL3 Modulates Radiation-Induced Cardiac Fibrosis via the Akt/mTOR Pathway
通过抑制帽依赖性起始，NRF2翻译阻断增强了淋巴瘤细胞对铁死亡和CAR-T免疫疗法的敏感性。	Manara, P.	PDF	N/A	NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy
对拟南芥中影响叶片毛状体发育和表皮金属积累的基因进行全基因组关联筛选	Bezvoda, R.	PDF	N/A	A genome-wide association screen for genes affecting leaf trichome development and epidermal metal accumulation in Arabidopsis
程序性细胞死亡和气孔密度调控花药在环境湿度变化下的开裂	Kampova, A.	PDF	N/A	Programmed cell death and stomatal density regulate anther opening in response to ambient humidity
乙烯通过ERF5-褪黑素-ERF104途径增强VvMYB14表达，从而调节葡萄籽中的苯丙烷途径	Gao, S.	PDF	N/A	Ethylene Modulates the Phenylpropanoid Pathway by Enhancing VvMYB14 Expression via the ERF5-Melatonin-ERF104 Pathway in Grape Seeds
一种内源性多肽PEP2调节拟南芥中的铁缺乏信号传导和根系生长。	Shikha, D.	PDF	N/A	An endogenous peptide PEP2 modulates Iron-deficiency signalling and root growth in Arabidopsis.
重新审视Vellozia Vand.的细胞遗传学：KLN1的免疫定位阐明了该属的染色体数目	Braz, G. T.	PDF	N/A	Revisiting the cytogenetics of Vellozia Vand.: immunolocalization of KLN1 elucidates the chromosome number for the genus
气候大脑 - 问卷、任务与神经影像数据集	Zaremba, D. A.	PDF	N/A	CLIMATE BRAIN - Questionnaires, Tasks and the Neuroimaging Dataset
中性粒细胞NADPH氧化酶打破炎症IL-1β/IL-17A循环，以增强呼吸道病毒感染期间的病原体清除。	Sofoluwe, A.	PDF	N/A	Neutrophil NADPH oxidase breaks the inflammatory IL-1beta/IL-17A circuit to enhance pathogen clearance during respiratory virus infections.
孤儿核受体NR4A3对于驻留记忆CD8+ T细胞的生成并非必需。	Odagiu, L.	PDF	N/A	The orphan nuclear receptor NR4A3 is dispensable for resident memory CD8+ T cell generation
通过抑制髓源性抑制细胞中的PI3K-gamma信号通路，预防手术引起的免疫抑制和转移。	Angka, L.	PDF	N/A	Preventing surgery induced immune suppression and metastases by inhibiting PI3K-gamma signalling in Myeloid-Derived Suppressor Cells.
IL-34通过赋予调节性T细胞新的非经典功能，在神经炎症期间保护脑屏障的完整性。	Van Hoecke, L.	PDF	N/A	IL-34 empowers regulatory T cells with novel non-canonical function to safeguard brain barrier integrity during neuro-inflammation.
检测粪菌移植后的微生物定植：利用安慰剂测序和培养富集的宏基因组学方法从噪声中筛选信号	Shekarriz, S.	PDF	N/A	Detecting microbial engraftment after FMT: sorting signals from noise using placebo sequencing and culture-enriched metagenomics
对入侵的大黄蜂（Bombus terrestris）进行全景观的宏条形码分析显示，肠道微生物组与花粉微生物组之间存在相互作用。	Haque, S.	PDF	N/A	Landscape-wide metabarcoding of the invasive bumblebee (Bombus terrestris) shows interactions among the gut microbiome and pollenbiome
在野生和圈养的狐猴中，口腔微生物群的恢复力和头发微生物群在宿主环境中的不稳定性	Burten, R. B.	PDF	N/A	The resilience of the oral microbiome and lability of the hair microbiome across host environments in wild and captive lemurs
欧洲旧石器时代晚期人口对气候变化的反应	Schmidt, I.	PDF	N/A	Demographic responses to climatic changes during the Final Palaeolithic in Europe
氮对沙丘石楠生态系统中Calluna vulgaris和Avenella flexuosa生长的影响：竞争与频率依赖性	Damgaard, C.	PDF	N/A	The effect of nitrogen on the growth of Calluna vulgaris and Avenella flexuosa in a dune heath ecosystem: competition and frequency-dependence
中欧永久农业的作物生产力介于有机农业和传统农业之间。	Reiff, J.	PDF	N/A	Crop productivity of Central European Permaculture is within the range of organic and conventional agriculture.
上下文和性别依赖的父本性成功与后代病原体抵抗力之间的联系	Liao, A.	PDF	N/A	Context- and sex-dependent links between sire sexual success and offspring pathogen resistance
饥饿时间决定其对果蝇雌性感染易感性的影响，与宿主进化历史无关	Basu, A.	PDF	N/A	Timing of starvation determines its effects on susceptibility to infection in Drosophila melanogaster females independent of host evolutionary history
高分辨率离子迁移分离与信使标记红外光谱联用平台的发展及其在精准结构表征中的应用	Harrilal, C.	PDF	N/A	Development of a Platform for High-Resolution Ion Mobility Separations Coupled with Messenger Tagging Infrared Spectroscopy for High-Precision Structural Characterizations
genomesizeR：一个用于基因组大小预测的R包	Mercier, C.	PDF	N/A	genomesizeR: An R package for genome size prediction
番茄和茄子幼苗茎部因感染Ralstonia pseudosolanacearum F1C1而出现的软化和半透明形态特征	Bhuyan, S.	PDF	N/A	Morphology of softening and translucency in the stems of tomato and eggplant seedlings due to infection by Ralstonia pseudosolanacearum F1C1
利用植硅体分析区分野生和驯化埃塞俄比亚香蕉（芭蕉科）	Castillo Cobo, C.	PDF	N/A	Differentiating wild and domesticated enset (Musaceae) using phytolith analysis
ElixirSeeker：一种利用注意力驱动融合分子指纹的机器学习框架，用于发现抗衰老化合物	Pan, Y.	PDF	N/A	ElixirSeeker: A Machine Learning Framework Utilizing Attention-Driven Fusion of Molecular Fingerprints for the Discovery of Anti-Aging Compounds
一种可扩展的代谢组学绝对定量方法	Ferro, L. S.	PDF	N/A	A scalable approach to absolute quantitation in metabolomics
蝙蝠听觉中脑中发声自我监测的神经表征	Ye, H.	PDF	N/A	Neural representation of vocalization self-monitoring in the bat auditory midbrain
LM11a-31抑制p75神经营养素受体（p75NTR）的切割，并在帕金森病细胞培养模型中具有神经保护作用。	Pokharel, P. V.	PDF	N/A	LM11a-31 Inhibits p75 Neurotrophin Receptor (p75NTR) Cleavage and is Neuroprotective in a Cell Culture Model of Parkinson's Disease.
超越免疫：疟原虫对蚊子代谢途径调控的转录组全景图	Garcia-Longoria, L.	PDF	N/A	Beyond immunity: a transcriptomic landscape of Plasmodium's modulation of mosquito metabolic pathways
将濒危的萨瓦纳树种Firmina major的基因组组装起来，这种树种是中国特有的。	Yang, J.	PDF	N/A	Genome assembly of Firmina major, an endangered savanna tree species endemic to China
START域从单一网络结构中生成特定旁系同源基因的调控网络	Holub, A. S.	PDF	N/A	START domains generate paralog-specific regulons from a single network architecture
对四种小鼠器官中基因、长链非编码RNA和转座子转录模式的调查揭示了共享和器官特异性的性别偏倚调控	Zhuang, Q. K.-W.	PDF	N/A	Survey of gene, lncRNA and transposon transcription patterns in four mouse organs highlights shared and organ-specific sex-biased regulation
流感人类T细胞反应的目标大多在H5N1中保持保守。	Sidney, J.	PDF	N/A	Targets of influenza Human T cell response are mostly conserved in H5N1
宿主年龄和营养如何影响专性共生菌与兼性共生菌的密度调控？来自采采蝇的启示	Whittle, M.	PDF	N/A	How does host age and nutrition affect density regulation of obligate versus facultative bacterial symbionts? Insights from the tsetse fly
壳外世界：温度如何塑造两种近缘海洋蜗牛的遗传变异	Wuitchik, D. M.	PDF	N/A	Outside your shell: how temperature shapes genetic variation in two species of congeneric marine snails
用于鲑鱼生态系统监测的eDNA采样系统	Deeg, C. M.	PDF	N/A	eDNA sampling systems for salmon ecosystem monitoring
实现具有生理运动补偿的真实三维扩散成像	Wang, Y.	PDF	N/A	Towards genuine three-dimensional diffusion imaging with physiological motion compensation
血液-脑屏障类器官的高级组织技术作为药物开发中的高通量毒性检测手段	Bell, L.	PDF	N/A	Advanced Tissue Technologies of Blood-Brain Barrier Organoids as High Throughput Toxicity Readouts in Drug Development
静息状态脑电图固有神经时间尺度的重测信度	Tang, X.	PDF	N/A	Test-retest reliability of resting-state EEG intrinsic neural timescales
在7特斯拉磁场下使用31P-MRS对小鼠大脑中肌酸激酶动力学进行体内定量研究	Tachrount, M.	PDF	N/A	In vivo quantification of creatine kinase kinetics in mouse brain using 31P-MRS at 7 Tesla
从第一性原理理解髓鞘化比率，其推导、用途及伪影	Gow, A.	PDF	N/A	Understanding The Myelin g ratio From First Principles, Its Derivation, Uses And Artifacts
背侧中缝5-羟色胺神经元内在动力学对长程输入的功能性分离	Lynn, M. B.	PDF	N/A	Functional separation of long-range inputs by intrinsic dynamics of dorsal raphe 5-HT neurons
呼吸对反应速度和准确性产生了系统性的时间滞后影响。	Harting, C.	PDF	N/A	Respiration shapes response speed and accuracy with a systematic time lag
利用具有图案化亲水斑块的双亲性微粒实现可调的皮升级液滴形成	Song, X.	PDF	N/A	Tunable picoliter-scale dropicle formation using amphiphilic microparticles with patterned hydrophilic patches
Doblin：从DNA条形码时间序列中推断占优势的克隆谱系	Serohijos, A.	PDF	N/A	Doblin: Inferring dominant clonal lineages from DNA barcoding time-series
RNAi药物在快速分裂细胞中的结构-沉默持续时间关系	Kremer, A.	PDF	N/A	Structure - silencing duration relationships in RNAi medicines in rapidly dividing cells
Mouse-Geneformer：一种用于小鼠单细胞转录组的深度学习模型及其跨物种应用	Shigenobu, S.	PDF	N/A	Mouse-Geneformer: A Deep Learning Model for Mouse Single-Cell Transcriptome and Its Cross-Species Utility
时间生物学节律对中枢神经系统中特定部位和细胞的miRNA和mRNA基因及网络的调控	Zacharias, A. M.	PDF	N/A	Chronobiological rhythms control of site- and cell-specific miRNA and mRNA genes and networks across the central nervous system
单价XBB.1.5 mRNA疫苗比二价WT/BA.5 mRNA疫苗更能持久且协调地引发对SARS-CoV-2刺突蛋白的抗体反应。	Barouch, S. E.	PDF	N/A	Monovalent XBB.1.5 mRNA Vaccine Recalls a More Durable and Coordinated Antibody Response to SARS-CoV-2 Spike than the Bivalent WT/BA.5 mRNA Vaccine
人表面活性蛋白A变异体的差异性免疫调节决定了SARS-CoV-2诱导的肺病严重程度	Jacob, I. B.	PDF	N/A	Differential Immunoregulation by Human Surfactant Protein A Variants Determines Severity of SARS-CoV-2-induced Lung Disease
细菌基因组编码的ParMs	Ali, S.	PDF	N/A	Bacterial genome encoded ParMs
鉴定出一种调节免疫反应的真菌抗菌内肽酶	Machata, S.	PDF	N/A	Identification of a fungal antibacterial endopeptidase that modulates immune responses
噬菌体间的竞争和生物膜降低了两种烈性噬菌体联合对抗铜绿假单胞菌的效力	Buerkle, M.	PDF	N/A	Phage-phage competition and biofilms reduce the efficacy of a combination of two virulent bacteriophages against Pseudomonas aeruginosa
铜绿假单胞菌表面行为中PilU的作用	Zhang, J.	PDF	N/A	The role of PilU in the surface behaviors of Pseudomonas aeruginosa
弓形虫转录因子AP2XII-8：G1期进展和寄生虫分裂的关键调控因子	Shi, Y.	PDF	N/A	Toxoplasma gondii transcription factor AP2XII-8: a key regulator of G1 phase progression and parasite division
卷曲乳杆菌S层蛋白调节女性下生殖道先天免疫反应和炎症。	Decout, A.	PDF	N/A	Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract.
LolA 和 LolB 在拟杆菌门中是保守的，对滑动运动和IX型分泌系统至关重要。	De Smet, T.	PDF	N/A	LolA and LolB are conserved in Bacteroidetes and are crucial for gliding motility and Type IX secretion.
在人类原代心脏内皮细胞中，基孔肯雅病毒的差异限制发生在病毒生命周期的多个步骤。	Spector, S. N.	PDF	N/A	Differential restriction of chikungunya virus in primary human cardiac endothelial cells occurs at multiple steps in the viral life cycle
鼻内接种表达Delta或Omicron B.1.1.529 SARS-CoV-2刺突蛋白的副流感病毒载体疫苗，可诱导黏膜和系统性免疫，并保护仓鼠免受同源和异源挑战。	Park, H.-S.	PDF	N/A	Intranasal parainfluenza virus-vectored vaccine expressing SARS-CoV-2 spike protein of Delta or Omicron B.1.1.529 induces mucosal and systemic immunity and protects hamsters against homologous and heterologous challenge
凝聚蛋白环挤压特性、障碍物以及在酿酒酵母同源搜索中的作用	Piveteau, V.	PDF	N/A	Condensin loop extrusion properties, roadblocks, and role in homology search in S. cerevisiae
开发一种DNA编码库筛选方法DEL Zipper，以增强对RNA靶向化学物质的研究	Ma, Z.	PDF	N/A	Development of a DNA-encoded library screening method DEL Zipper to empower the study of RNA-targeted chemical matter
人肺基底细胞在SARS-CoV-2感染后释放的PROS1有助于上皮细胞修复并限制炎症。	Simakou, T.	PDF	N/A	PROS1 released by human lung basal cells upon SARS-CoV-2 infection facilitates epithelial cell repair and limits inflammation.
参考样本的表观基因组、转录组和蛋白质组特征分析	Nepal, C.	PDF	N/A	Epigenomic, transcriptomic and proteomic characterizations of reference samples
线粒体二羧酸载体在体内介导肝脏糖异生作用	Pape, D. J.	PDF	N/A	The mitochondrial dicarboxylate carrier mediates in vivo hepatic gluconeogenesis
通过铁蛋白笼的超分子组装生成的磁性蛋白质聚集体——一种用于酶固定化的模块化策略	Olcucu, G.	PDF	N/A	Magnetic Protein Aggregates Generated by Supramolecular Assembly of Ferritin Cages - A Modular Strategy for the Immobilization of Enzymes
使用基于肽的传感器直接测量生物膜中的PIP2密度	Menon, V. K.	PDF	N/A	Direct measurement of PIP2 densities in biological membranes using a peptide-based sensor
目标条件扩散生成强效TNFR超家族拮抗剂和激动剂	Gloegl, M.	PDF	N/A	Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
玻璃态表面活性剂实现超高浓度生物治疗药物	Jons, C. K.	PDF	N/A	Glassy Surfactants Enable Ultra-High Concentration Biologic Therapeutics
清醒大鼠胃运动的磁共振成像	Wang, X.	PDF	N/A	Magnetic Resonance Imaging of Gastric Motility in Conscious Rats
从空间转录组数据中提取生物学相关的信号	Radkevich, E.	PDF	N/A	Informing biologically relevant signal from spatial transcriptomic data
iSeqsSearch：为iBlast/iMMSeqs2/iDiamond设计的增量蛋白质搜索工具	Yoo, H.	PDF	N/A	iSeqsSearch: Incremental Protein Search for iBlast/iMMSeqs2/iDiamond
CodonTransformer：一种使用上下文感知神经网络的多物种密码子优化器	Fallahpour, A.	PDF	N/A	CodonTransformer: a multispecies codon optimizer using context-aware neural networks
计算癌症治疗的斯塔克伯格均衡	Ganzfried, S.	PDF	N/A	Computing Stackelberg Equilibrium for Cancer Treatment
探测他人的存在：跨脑尺度的概率推断揭示了增强的兴奋性突触效能	Esmaeili, A.	PDF	N/A	Probing other's Presence: Probabilistic Inference Across Brain Scales Reveals Enhanced Excitatory Synaptic Efficacy
认知与生活方式相关的老龄化人脑海马微结构变异	Agyekum, T.	PDF	N/A	Cognitive-and lifestyle-related microstructural variation in the ageing human hippocampus
无监督的分段线性解码能够在多任务脑机接口中准确预测肌肉活动。	Ma, X.	PDF	N/A	Unsupervised, piecewise linear decoding enables an accurate prediction of muscle activity in a multi-task brain computer interface
眼动控制中的努力：指令和奖励在时空眼动动力学中的作用	Wolf, C.	PDF	N/A	Effort in Oculomotor Control: Role of Instructions and Reward on Spatio-temporal Eye Movement Dynamics
一种涉及双向耦合的外侧和内侧内嗅皮层层的统一模型，用于海马体空间和物体细胞	Patil, B. K.	PDF	N/A	A unified model of hippocampal spatial and object cells involving bidirectionally coupled Lateral and Medial Entorhinal Cortical layers
III型干扰素通过触发细胞死亡独立于STAT激活抑制甲型流感病毒感染	Prus, W.	PDF	N/A	Type III interferons suppress influenza A virus infection independently of STAT activation by triggering cell death
计算代谢建模揭示了小鼠癌症恶病质期间肠道微生物群在代谢转变中的作用	Moissl-Eichinger, C.	PDF	N/A	Computational metabolic modeling unveils gut microbiomes role in metabolic shifts during murine cancer cachexia
适用于快速培养乳酸杆菌（Lactobacillus iners）及其他阴道细菌的实用媒体配方	Serrador, D.	PDF	N/A	Practical Media Formulations for Rapid Growth of Lactobacillus iners and Other Vaginal Bacteria
野生型驯化：在丰富培养基中，内在代谢特性的丧失被文化所掩盖	Vezina, B.	PDF	N/A	Wild type domestication: loss of intrinsic metabolic traits concealed by culture in rich media
金合欢属植物（Acacia gerrardii），作为一种沙漠植物，是可持续获取具有抗菌特性的天然产品的来源。	Elkahoui, S.	PDF	N/A	Acacia gerrardii, a desert plant as a sustainable source of natural products with antimicrobial properties
蛋白质-配体复合物中的质子化效应——以内酰胺蛋白酶和抑肽酶A为例，结合计算和实验方法进行研究	Vatheuer, H.	PDF	N/A	Protonation effects in protein-ligand complexes - a case study of endothiapepsin and pepstatin A with computational and experimental methods
DYF-5通过影响列车转向来调节鞭毛内运输	Mul, W.	PDF	N/A	DYF-5 regulates intraflagellar transport by affecting train turnaround
一种基于纳米抗体的方法，用于在活细胞中捕获和可视化二元蛋白质复合物的相互作用	Sleiman, N. H.	PDF	N/A	A nanobody-based approach to capture and visualize interactions of binary protein complexes in living cells
解码酵母热休克中的转录记忆及RNA结合蛋白Mip6的功能意义	Rodriguez-Navarro, S.	PDF	N/A	Decoding Transcriptional Memory in Yeast Heat Shock and the Functional Implication of the RNA Binding Protein Mip6
胞嘧啶-5 DNA甲基化介绍使细胞对氧化损伤敏感	Krwawicz, J.	PDF	N/A	Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage
UM171和新生型癌症突变体的结构模拟物通过招募E3连接酶KBTBD4来共同选择HDAC1/2	Chen, Z.	PDF	N/A	Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment
53BP1缺陷导致通过断裂诱导复制（BIR）进行超重组	Shah, S. B.	PDF	N/A	53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR)
计算和报告基于DIA蛋白质组学的变异系数	Brenes, A. J.	PDF	N/A	Calculating and Reporting Coefficients of Variation for DIA-based Proteomics
2.5埃分辨率下酵母ADP-肌动蛋白丝的冷冻电镜重建。与哺乳动物和禽类F-肌动蛋白的比较。	Stevenson, S. R.	PDF	N/A	CryoEM Reconstruction of Yeast ADP-Actin Filament at 2.5 Angstrom resolution. A comparison with mammalian and avian F-actin.
通过明胶-弹性纤维增强水凝胶进行阴道组织工程	Zambuto, S. G.	PDF	N/A	Vaginal Tissue Engineering via Gelatin-Elastin Fiber-Reinforced Hydrogels
材料成分和植入部位影响体内设备降解速率	Pawelec, K.	PDF	N/A	Material Composition and Implantation Site Affect in vivo Device Degradation Rate
通过考虑树突计算来克服运动传感器模型的局限性	Luna, R.	PDF	N/A	Overcoming the limitations of motion sensor models by considering dendritic computations
一种来自天门冬科植物的新型Polerovirus，其RNA沉默抑制蛋白P0定义了该病毒的种类。	Dekker, R. J.	PDF	N/A	A new Polerovirus species in plants from the Asparagaceae family defined by its RNA-silencing repressor protein P0
# BioRxiv 2024-09-12 Papers

标题	作者	PDF链接	代码仓库	Title
双色光对神经元的高时间精度激活和抑制	Mermet-Joret, N.	PDF	N/A	Dual-color optical activation and suppression of neurons with high temporal precision
神经调节器通过在超通道中转移活动流，在递归神经网络中生成多种与上下文相关的行为。	Tsuda, B.	PDF	N/A	Neuromodulators generate multiple context-relevant behaviors in a recurrent neural network by shifting activity flows in hyperchannels
CHAS是一种反卷积工具，用于推断神经和精神疾病的大脑组蛋白乙酰化研究中的细胞类型特异性特征。	Murphy, K. B.	PDF	N/A	CHAS, a deconvolution tool, infers cell type-specific signatures in bulk brain histone acetylation studies of neurological and psychiatric disorders
健康年轻成人步态控制中认知参与的运动学和神经肌肉特征	LANA, V.	PDF	N/A	Kinematic and neuromuscular characterization of cognitive involvement in gait control in healthy young adults
骨骼肌和神经肌肉执行器的Hill型模型：系统性综述	Caillet, A. H.	PDF	N/A	Hill-type models of skeletal muscle and neuromuscular actuators: a systematic review
心形蚌壳通过捆绑的光纤电缆和聚光透镜将阳光传递给共生藻类。	McCoy, D. E.	PDF	N/A	Heart cockle shells transmit sunlight to photosymbiotic algae using bundled fiber optic cables and condensing lenses
PACESS：基于AI的大规模三维骨髓组织图像细胞提取与空间统计	Adams, G.	PDF	N/A	PACESS: Practical AI-based Cell Extraction and Spatial Statistics for large 3D bone marrow tissue images
使用针电极阵列对糖尿病小纤维周围神经病变进行经皮电生理记录：小鼠和人类的实验研究	Blaszkiewicz, M.	PDF	N/A	Transdermal Electrophysiological Recordings of Diabetic Small Fiber Peripheral Neuropathy Using a Needle Electrode Array in Mice and Men
小ARF样2 GTP酶TITAN 5与铁调节转运蛋白1的动态调控相关	Mohr, I.	PDF	N/A	Small ARF-like 2 GTPase TITAN 5 is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER 1
zol & fai：大规模目标基因簇的检测与进化研究	Salamzade, R.	PDF	N/A	zol & fai: large-scale targeted detection and evolutionary investigation of gene clusters
用于研究果蝇联想学习的驱动线	Shuai, Y.	PDF	N/A	Driver lines for studying associative learning in Drosophila
SARS-CoV-2刺突抗体与登革病毒发生交叉反应，并在体外和体内增强感染	Jakhar, K.	PDF	N/A	SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in-vitro and in-vivo
JointPRS：一种数据自适应框架，用于整合遗传相关性的多群体遗传风险预测	Xu, L.	PDF	N/A	JointPRS: A Data-Adaptive Framework for Multi-Population Genetic Risk Prediction Incorporating Genetic Correlation
使用基于聚类的排列检验来估计MEG/EEG起始时间：问题有多严重？	Rousselet, G. A.	PDF	N/A	Using cluster-based permutation tests to estimate MEG/EEG onsets: how bad is it?
TIPE通过促进PKM2/HIF-1α轴的糖酵解作用，在黑色素瘤中驱动类似癌症干细胞的表型。	Tian, M.	PDF	N/A	TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma
流感聚合酶活性位点的高分辨率结构揭示了复制起始类似构型中保守的双碱性基序在PA亚基中的关键作用	Cusack, S.	PDF	N/A	High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit
人类肌肉中大量运动单位的识别揭示了神经调质输入对速率编码的多样影响	Avrillon, S.	PDF	N/A	The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding
在单细胞分辨率下通过基因信号模式分析绘制基因空间图谱	Venkat, A.	PDF	N/A	Mapping the gene space at single-cell resolution with gene signal pattern analysis
在衰老过程中，人类细胞的着丝粒失活是可以被挽救的。	Sikder, S.	PDF	N/A	Centromere inactivation during aging can be rescued in human cells
肠道与鼻咽微生物群组成之间的关系可以预测COVID-19的严重程度。	Martin-Castano, B.	PDF	N/A	The relationship between gut and nasopharyngeal microbiome composition can predict the severity of COVID-19
Caspase-2通过杀死具有多余中心体的细胞来发挥作用。	Rizzotto, D.	PDF	N/A	Caspase-2 kills cells with extra centrosomes
多功能聚合结构域决定了拟南芥中表观遗传沉默的开始	Schulten, A.	PDF	N/A	Multifunctional polymerization domains determine the onset of epigenetic silencing in Arabidopsis
体积电子显微镜揭示了人死后前额叶皮层的3D突触纳米结构	Glausier, J. R.	PDF	N/A	Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex
沙门氏菌利用植物免疫系统产生的活性氧物种来增强其定殖能力。	Tzpilevich, E.	PDF	N/A	Salmonella exploits the reactive oxygen species generated by the plant immune system to enhance colonization
不确定性的多重及特定主题角色在奖励导向决策中的作用	Paunov, A.	PDF	N/A	Multiple and subject-specific roles of uncertainty in reward-guided decision-making
通过计算允许先前有问题的序列参数的第二种对比度，对基于MP2RAGE的R1映射中的B1+不均匀性容差进行3T研究	Ruijters, L.	PDF	N/A	A 3T investigation of B1+-inhomogeneity tolerance in MP2RAGE-based R1-mapping by calculating second contrast that permits previously problematic sequence parameters
寒冷诱导脑区选择性细胞活动依赖性脂质代谢	Min, H.	PDF	N/A	Cold induces brain region-selective cell activity-dependent lipid metabolism
最快和最密集反应的协调体现了老鼠类似人类的反应时间。	Kim, C. H.	PDF	N/A	Harmonization of the fastest and densest responses embodies the humanlike reaction time of mice
细菌应激颗粒通过排除核糖核酸酶来保护mRNA	Pei, L.	PDF	N/A	Bacterial stress granule protects mRNA through ribonucleases exclusion
前额叶和颞叶区域的双向连接变化反映了多声部音乐中的图形-背景反转	Kim, C. H.	PDF	N/A	Bidirectional connectivity changes in the frontotemporal areas reflect figure-ground reversal in multivoiced music
未预料到的共价抑制剂和合成配体与PPARγ的共结合机制	Shang, J.	PDF	N/A	Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPARgamma
实验性创伤性脑损伤后海马θ-γ耦合和锋电位场相干性的破坏	Adam, C. D.	PDF	N/A	Disrupted Hippocampal Theta-Gamma Coupling and Spike-Field Coherence Following Experimental Traumatic Brain Injury
无脊椎动物中Cdk4/6-Cdkn2系统的演化	Yuki, S.	PDF	N/A	Evolution of the Cdk4/6-Cdkn2 system in invertebrates
昼夜节律调节血流对基于纳米颗粒的靶向药物递送在虚拟体内动脉几何结构中的影响	Goraya, S. A.	PDF	N/A	Effect of Circadian Rhythm Modulated Blood Flow on Nanoparticle based Targeted Drug Delivery in Virtual In Vivo Arterial Geometries
一个转录因子五重奏调控水稻鞘鞘表达	Hua, L.	PDF	N/A	A transcription factor quintet orchestrating bundle sheath expression in rice
人类下丘中的快速且刺激特异性的异常检测	Wetekam, J.	PDF	N/A	Rapid and Stimulus-Specific Deviance Detection in the Human Inferior Colliculus
regulaTER：一个用于研究转座元件调控作用的R语言库。	Eskier, D.	PDF	N/A	regulaTER: An R Library to Study the Regulatory Roles of Transposable Elements.
一种能够穿越血脑屏障的肽-神经降压素偶联物，在小鼠癫痫持续状态后诱导了与抗惊厥、神经保护和抗炎特性相关的药理性体温过低。	Ferhat, L.	PDF	N/A	A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
内在无序蛋白质凝聚体中动力学的异质性减缓	Mukherjee, S.	PDF	N/A	Heterogeneous Slowdown of Dynamics in the Condensate of an Intrinsically Disordered Protein
BioLP-bench：评估大型语言模型对生物实验室协议的理解能力	Ivanov, I.	PDF	N/A	BioLP-bench: Measuring understanding of biological lab protocols by large language models
在烟草中异源生产环肽素B：揭示植物特异性插入结构域在蛋白质功能和亚细胞定位中的作用	Muthusamy, S.	PDF	N/A	Heterologous Production of Cyprosin B in Nicotiana benthamiana: Unveiling the Role of the Plant-Specific Insert Domain in Protein Function and Subcellular Localization
遗传抑制相互作用在不同遗传背景下高度保守	Paltenghi, C.	PDF	N/A	Genetic suppression interactions are highly conserved across genetic backgrounds
柱状胆碱能神经传递到果蝇T5细胞	Samara, E.	PDF	N/A	Columnar cholinergic neurotransmission onto T5 cells of Drosophila
两种形态迥异的蜂媒授粉茄科植物花朵中花粉的命运	Vasquez-Castro, C. A.	PDF	N/A	The fate of pollen in two morphologically contrasting buzz-pollinated Solanum flowers
磷酸酶非依赖性抑制黏膜炎症和疾病进展的沙门氏菌SopB	Diab, N.	PDF	N/A	Phosphatase-independent suppression of mucosal inflammation and disease progression by Salmonella SopB
内皮CD45在调节动脉粥样硬化中的内皮间质转化的新作用	Peng, Q.	PDF	N/A	Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis
海马体中奖励的预测编码	Yaghoubi, M. H.	PDF	N/A	Predictive Coding of Reward in the Hippocampus
丝虫精子发生过程中重组、X染色体失活及着丝粒蛋白的动态变化	Toubiana, W.	PDF	N/A	Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis
增加留尼汪岛节肢动物名录	Nibouche, S.	PDF	N/A	Additions to the list of arthropods of Reunion Island
质子结合的变构调节赋予囊泡谷氨酸转运蛋白氯离子活化和谷氨酸选择性	Borghans, B.	PDF	N/A	Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters
转录因子Traffic jam在果蝇卵巢中调控体细胞piRNA通路	Alizada, A.	PDF	N/A	The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries
急性饮食甲硫氨酸限制突显了新皮质发育对代谢变化的敏感性	Saha, S.	PDF	N/A	Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations
裂变酵母SUMO靶向泛素连接酶Slx8在功能上与核周的成簇着丝粒和沉默的交配型区域相关联。	Chakraborty, S.	PDF	N/A	The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery
在磷酸盐限制条件下，革兰氏阴性ESKAPE病原体通过替代脂质合成途径促进抗生素耐受性。	Olea-Ozuna, R. J.	PDF	N/A	Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens
IgSF蛋白DIP-α和Dpr10的关键亲和窗口对于适当的运动神经元树突化是必需的。	Lopez, D.	PDF	N/A	A critical affinity window for IgSF proteins DIP-alpha and Dpr10 is required for proper motor neuron arborization
河流丽鱼（辐鳍鱼纲，慈鲷科）的完整线粒体基因组，重点关注盲丽鱼L. lethops	Jimenez, S.	PDF	N/A	Complete mitochondrial genomes of riverine Lamprologus (Actinopterygii, Cichlidae) with an emphasis on the blind cichlid L. lethops
适应性唤醒调节：通过儿茶酚胺增强唤醒来药理学地改变耶克斯-多德森曲线的峰值	Beerendonk, L.	PDF	N/A	Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal
ABHD11介导的去甘露糖化作用调控TCA循环和T细胞代谢	Grice, G. L.	PDF	N/A	ABHD11 mediated deglutarylation regulates the TCA cycle and T cell metabolism
母体致肥胖饮食在中孕期会破坏子宫内膜的免疫和血管稳态，但不会影响螺旋动脉的重塑。	Bellissimo, C. J.	PDF	N/A	Maternal obesogenic diet disrupts mid-gestation decidual immune and vascular homeostasis without impairing spiral artery remodelling
遗传性铜缺乏和儿童神经退行性变模型中的适应性蛋白质合成	Lane, A. R.	PDF	N/A	Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
蛋白质稳态和代谢功能障碍在特定的一组储存诱导的衰老红细胞中，这些红细胞被靶向清除	Peltier, S.	PDF	N/A	Proteostasis and metabolic dysfunction in a distinct subset of storage-induced senescent erythrocytes targeted for clearance
人类动脉粥样硬化斑块的综合单细胞图谱	Traeuble, K.	PDF	N/A	Integrated single-cell atlas of human atherosclerotic plaques
甲型流感病毒利用宿主细胞中膜细胞骨架肌动蛋白丝的运动性进行其基因组的包装。	Wang, I.-H.	PDF	N/A	Influenza A virus exploits the motility of membrane cytoskeletal actomyosin filaments for its genome packaging in the host cell
胞内体重组疗法：一种从囊性纤维化中进行的生物学拯救	Cho, W. J.	PDF	N/A	Porosome reconstitution therapy: A biologic rescue from cystic fibrosis
自闭症和智力障碍相关MYT1L基因突变影响人类皮层中间神经元的分化、成熟和生理功能	Prakasam, R.	PDF	N/A	Autism and Intellectual Disability-Associated MYT1L Mutation Alters Human Cortical Interneuron Differentiation, Maturation, and Physiology
吉尔伽美什，果蝇酪蛋白激酶1g，对于肌球蛋白依赖的连接增强和上皮折叠是必需的。	Gu, L.	PDF	N/A	gilgamesh, Drosophila casein kinase 1g, is required for myosin-dependent junction strengthening and epithelial folding
心脏成纤维细胞通过胶原蛋白信号通路调节心肌和冠状血管的发育。	Deng, Y.	PDF	N/A	Cardiac Fibroblasts regulate myocardium and coronary vasculature development via the collagen signaling pathway
大规模小鼠突变分析鉴定出影响脊椎发育的新基因。	Ibarra-Soria, X.	PDF	N/A	Large-scale mouse mutagenesis identifies novel genes affecting vertebral development.
卵母细胞锌转运蛋白Slc39a10/Zip10是小鼠受精过程中锌火花调节器。	Kageyama, A.	PDF	N/A	The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice.
弓形虫感染会误导胎盘滋养层细胞谱系的分化	Cabo, L. F.	PDF	N/A	Toxoplasma gondii infection misdirects placental trophoblast lineage specification
长期活体成像、细胞鉴定及再生甲壳动物腿中的细胞追踪	Cevrim, C.	PDF	N/A	Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
电泳相关离子迁移技术在毛细管电泳质谱单细胞蛋白质组学中的应用	Shen, B.	PDF	N/A	Electrophoresis-Correlative Ion Mobility Deepens Single-cell Proteomics in Capillary Electrophoresis Mass Spectrometry
Notch活性的基本和双重作用对自然转分化事件的影响	Daniele, T.	PDF	N/A	Essential and dual effects of Notch activity on a natural transdifferentiation event
深度学习在荧光全内反射显微镜中动态胞吐事件的检测	Lachuer, H.	PDF	N/A	Deep learning detection of dynamic exocytosis events in fluorescence TIRF microscopy
硫胺素预处理控制马铃薯早疫病：其有效性及分子机制的研究	Berrian, T. W.	PDF	N/A	Thiamin priming to control early blight in potato: investigation of its effectiveness and molecular mechanisms
细胞松弛素B对肌动蛋白结合蛋白功能的急性干扰	Lambert, C.	PDF	N/A	Differential interference with actin-binding protein function by acute Cytochalasin B
蜕膜自然杀伤细胞促进绒毛外滋养层发育途径：来自滋养层类器官共培养的证据	Zych, M.	PDF	N/A	Decidual natural killer cells promote extravillous trophoblast developmental pathways: evidence from trophoblast organoid co-cultures
秀丽隐杆线虫染色体内重组率的菌株间变异	Matharage, D. U.	PDF	N/A	Inter-strain variation in intra-chromosomal rates of recombination in Caenorhabditis elegans
果蝇饮食限制介导的寿命结果中的随机性	Mosley, O. L.	PDF	N/A	Stochasticity in dietary restriction-mediated lifespan outcomes in Drosophila
ATG9小泡是一种细胞内纳米小泡的亚型。	Fesenko, M.	PDF	N/A	ATG9 vesicles are a subtype of intracellular nanovesicle
母亲孕期抑郁症状与新生儿胼胝体完整性之间的关联及其与孕期头发皮质醇浓度的关系	Mariani Wigley, I. L. C.	PDF	N/A	Association between maternal depressive symptoms and hair cortisol concentration during pregnancy with corpus callosum integrity in newborns
利用三倍频显微镜对生理上保存完好的人脑组织中的髓鞘病理进行动态成像	Meijns, N.	PDF	N/A	Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy
在环境与遗传空间中的杂种优势	Sandstedt, G. D.	PDF	N/A	Heterosis across an environmental and genetic space
突触小泡停靠与融合孔调节：神经钙传感器Synaptotagmin-1的作用	Tsemperouli, M.	PDF	N/A	Vesicle docking and fusion pore modulation by the neuronal calcium sensor Synaptotagmin-1
水滴的燃烧玻璃效应在拟南芥叶片叶绿体基质中触发了内质网衍生的钙响应	Kuang, D.	PDF	N/A	Burning glass effect of water droplets triggers an ER-derived calcium response in the chloroplast stroma of Arabidopsis thaliana leaves
通过时间和波长分辨的氧化还原生物传感器以及叶绿素荧光量化电子传递相关的氧化信号	Hipsch, M.	PDF	N/A	Quantification of electron transport-related oxidative signals by time and wavelength-resolved redox biosensors and chlorophyll fluorescence
探索玉米地方品种根系表型的产量稳定性和适应性景观的计算机模拟	Lopez-Valdivia, I.	PDF	N/A	Exploring yield stability and the fitness landscape of maize landrace root phenotypes in silico
不同的输入特异性机制使得突触前稳态可塑性成为可能	Chien, C.	PDF	N/A	Distinct input-specific mechanisms enable presynaptic homeostatic plasticity
ERK2二聚体在突触可塑性和记忆中的作用	Ojea Ramos, S.	PDF	N/A	Role of ERK2 dimerization in synaptic plasticity and memory
辅助调节通过NLRP3/IL-1途径塑造适应性免疫反应，并促进训练性免疫耐受。	Boccia, T.	PDF	N/A	Adjuvant conditioning shapes the adaptive immune response and promotes trained immunotolerance via NLRP3/IL-1
雷帕霉素改变了雌性果蝇对氨基酸和糖的摄食偏好	Yu, G.	PDF	N/A	Rapamycin alters the feeding preference for amino acids and sugar in female Drosophila
突触间可塑性变异性的平衡，以生成输入端广泛的递质释放恒定性。	Aghi, K.	PDF	N/A	Synapse-to-synapse plasticity variability balanced to generate input-wide constancy of transmitter release
小鼠中自发再生的皮质脊髓神经元	Fait, B. W.	PDF	N/A	Spontaneously regenerative corticospinal neurons in mice
辅助嗅球中的突触抑制调节信息素定位学习和记忆	Marathe, S. D.	PDF	N/A	Synaptic inhibition in the accessory olfactory bulb regulates pheromone location learning and memory
利用突触囊泡释放和再循环机制进行分子递送至神经元	Yee, K. K.	PDF	N/A	Harnessing Synaptic Vesicle Release and Recycling Mechanism for Molecule Delivery to Neurons
极端疼痛毒液的多重作用机制	Borjon, L. J.	PDF	N/A	Multiple mechanisms of action of an extremely painful venom
神经肽能对胆碱能传递的调控丧失会引发肌肉细胞中由CaV1介导的稳态补偿	Shao, J.	PDF	N/A	Loss of neuropeptidergic regulation of cholinergic transmission induces CaV1-mediated homeostatic compensation in muscle cells
整合双目视觉和运动状态以促进猎物追捕	Tian, G.	PDF	N/A	Integration of binocular vision and motor state to promote prey pursuit
m6A RNA修饰在转录组学层面调节了衰老和突触核蛋白病小鼠模型中的突触功能。	Chopra, A.	PDF	N/A	The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy
使用冷冻电镜和人工智能进行蛋白质鉴定指导了改进的样品纯化	Carr, K. D.	PDF	N/A	Protein identification using cryo-EM and artificial intelligence guides improved sample purification
外纹状皮质中误报的神经动力学基础	Sahoo, B.	PDF	N/A	Neural Dynamics Underlying False Alarms in Extrastriate Cortex
Context-Seq: 基于CRISPR-Cas9靶向纳米孔测序的抗菌药物耐药性传播动力学研究	Fuhrmeister, E. R.	PDF	N/A	Context-Seq: CRISPR-Cas9 Targeted Nanopore Sequencing for Transmission Dynamics of Antimicrobial Resistance
解锁隐藏噬菌体多样性，以完成BASEL收藏，系统探索噬菌体-宿主相互作用	Humolli, D.	PDF	N/A	Unlocking hidden phage diversity to complete the BASEL collection for systematic exploration of phage-host interactions
一种古菌的CBASS系统能在不杀死宿主细胞的情况下消除病毒	Choudhary, D. K.	PDF	N/A	An archaeal CBASS system eliminates viruses without killing the host cells
西高加索蝙蝠病毒在意外宿主体内的免疫学发现	Castellan, M.	PDF	N/A	Immunological findings of West Caucasian bat virus in an accidental host
评估TRX和DUF148抗原用于检测犬类潜伏期麦地那龙线虫（Dracunculus medinensis）感染的性能	Hakimi, H.	PDF	N/A	Assessing the performance of TRX and DUF148 antigens for detection of prepatent Guinea worm (Dracunculus medinensis) infection in dogs
计算研究表明揭示了条形柄锈菌小麦专化型效应蛋白的结构特征和新家族	Asghar, R.	PDF	N/A	Computational studies reveal structural characterization and novel families of Puccinia striiformis f. sp. tritici effectors
通过凝集素微阵列对乳酸乳球菌乳酸亚种突变体进行糖型分析	Suzuki, E.	PDF	N/A	Glyco-phenotyping of mutants of Lacticaseibacillus paracasei by lectin microarray
对单个噬菌体和噬菌体混合物的宏基因组分析显示，存在温和噬菌体和细菌DNA的污染情况。	Peng, X.	PDF	N/A	Metagenomic analyses of single phages and phage cocktails show instances of contamination with temperate phages and bacterial DNA
不同寡聚态流感病毒核蛋白的多克隆和单克隆抗体分析	Myers, M. L.	PDF	N/A	Analysis of polyclonal and monoclonal antibody to the influenza virus nucleoprotein in different oligomeric states
ves1α基因表达是巴贝斯虫感染的红细胞与内皮细胞粘附的主要决定因素。	Hakimi, H.	PDF	N/A	ves1α genes expression is the major determinant of Babesia bovis-infected erythrocytes cytoadhesion to endothelial cells
一种基于黄素的新型革兰氏阳性菌Microbacterium deferre sp. nov.菌株A1-JK中的胞外电子传递策略，该菌株从电缆细菌富集物中分离得到。	Lustermans, J. J. M.	PDF	N/A	A flavin-based extracellular electron transfer strategy in a novel gram-positive microbe Microbacterium deferre sp. nov. strain A1-JK, isolated from cable bacteria enrichments
电磁波能破坏SARS-CoV-2的刺突蛋白，并降低SARS-CoV-2病毒样颗粒（SC2-VLP）的感染性。	Granatir, S.	PDF	N/A	Electromagnetic waves destabilize the SARS-CoV-2 Spike protein and reduce SARS-CoV-2 Virus-Like Particle (SC2-VLP) infectivity
通过筛选组蛋白突变体，我们发现组蛋白H3的N端尾部内存在一个区域，该区域调控Cyc8在活性FLO1位点上独立于Tup1的抑制作用。	Singh, R.	PDF	N/A	Screening of histone mutants reveals a domain within the N-terminal tail of histone H3 that regulates the Tup1-independent repressive role of Cyc8 at the active FLO1
通过调节炎症和促消退脂质介质的平衡，改善体积性肌肉损失损伤的功能性肌肉再生	Turner, T. C.	PDF	N/A	Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid Mediators
NucBalancer：优化样本混合用于测序的条码序列选择流程	Gupta, S.	PDF	N/A	NucBalancer: Streamlining Barcode Sequence Selection for Optimal Sample Pooling for Sequencing
应激介导的生长决定大肠杆菌分裂位点的形态发生	Pelech, P.	PDF	N/A	Stress-mediated growth determines E. coli division site morphogenesis
凝血因子XII参与了肾素激活、心力衰竭进展及死亡率的相关过程。	Gladysheva, I. P.	PDF	N/A	Coagulation factor XII contributes to renin activation, heart failure progression, and mortality
一种KCa 2.2/2.3开放剂可逆转ET-1诱导的高血压小鼠NLRP3的激活	Sobrano Fais, R.	PDF	N/A	A KCa 2.2/2.3 opener reverses ET-1 induced NLRP3 activation in hypertensive mice
细菌的储层计算	Faulon, J.-L.	PDF	N/A	Reservoir Computing with Bacteria
血清素能致幻剂DOI会损害听觉皮层的异常检测能力。	Horrocks, M.	PDF	N/A	The serotonergic psychedelic DOI impairs deviance detection in the auditory cortex
不依赖宿主蛋白酶的寨卡病毒感染性成熟颗粒的生物发生	Dowd, K. A.	PDF	N/A	pr-independent biogenesis of infectious mature Zika virus particles
综合宿主体内感染动力学揭示了被忽视的媒介物种白纹伊蚊（Aedes scutellaris）具有较高的虫媒病毒传播潜力	Samung, Y.	PDF	N/A	Comprehensive intra-host infection kinetics reveals high arbo-flavivirus transmission potential by neglected vector species, Aedes scutellaris
双天线N-聚糖作为MARTX毒素在弧菌致病性中的受体	Chen, J.	PDF	N/A	Biantennary N-glycans As Receptors for MARTX Toxins in Vibrio Pathogenesis
卡尔斯巴德洞窟国家公园的洞穴池中存在着多样化的噬菌体群落和新型病毒序列。	Ulbrich, J.	PDF	N/A	Cave pools in Carlsbad Caverns National Park contain diverse bacteriophage communities and novel viral sequences
无机多磷酸盐与严紧反应共同调控大肠杆菌的细胞分裂和细胞形态	Hamm, C. W.	PDF	N/A	Inorganic polyphosphate and the stringent response coordinately control cell division and cell morphology in Escherichia coli
衣原体效应蛋白Tarp的N端与宿主Hippo通路相互作用。	Aranjuez, G. F.	PDF	N/A	The N-terminus of the Chlamydia trachomatis effector Tarp engages the host Hippo pathway
MtvS调节弗朗西氏菌V-A型CRISPR-Cas系统	Brodmann, M.	PDF	N/A	MtvS Regulates the Francisella Type V-A CRISPR-Cas System
Hox转录因子Ultrabithorax的协同DNA和RNA结合能力协调剪接并塑造体内同源异型功能	Blanco, C.	PDF	N/A	Synergistic DNA and RNA binding of the Hox transcription factor Ultrabithorax coordinates splicing and shapes in vivo homeotic functions
Cas9核酸酶的策略性靶向扩展了串联基因阵列	Takesue, H.	PDF	N/A	Strategic targeting of Cas9 nickase expands tandem gene arrays
营养缺乏会激活与炎症性肠病风险相关的细胞外基质重塑基因增强子，这一过程在成纤维细胞中尤为显著。	Secchia, S.	PDF	N/A	Nutrient starvation activates ECM remodeling gene enhancers associated with inflammatory bowel disease risk in fibroblasts
由III组代谢型谷氨酸受体介导的抑制作用调节着缰核的活动及防御行为	Ostenrath, A. M.	PDF	N/A	Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors
稳定选择使复杂性状的尾部富集了具有较大效应的罕见等位基因。	Ori, A. P.	PDF	N/A	Stabilising selection enriches the tails of complex traits with rare alleles of large effect
老年人大脑中微小RNA的基因调控及其对神经精神疾病的影响	Vattathil, S. M.	PDF	N/A	Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions
利用批量和靶向单细胞激活技术对基因组调控景观进行敏感解剖	Vucicevic, D.	PDF	N/A	Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation
GAF结构域介导肌醇焦磷酸底物在PPIP5K磷酸酶中的通道作用	Raia, P.	PDF	N/A	A GAF domain mediates inositol pyrophosphate substrate channeling in PPIP5K phosphatases
二聚体SMC复合物进行的环挤压对称性依赖于DNA张力	Pradhan, B.	PDF	N/A	Symmetry of loop extrusion by dimeric SMC complexes is DNA-tension-dependent
ARF降解定义了生长素反应中一个高度保守的步骤。	de Roij, M.	PDF	N/A	ARF degradation defines a deeply conserved step in auxin response
单锥光感受器通过注视转移来体验全局图像统计信息。	Morimoto, T.	PDF	N/A	Single cone photoreceptors experience global image statistics through gaze shifts
α5-GABAA受体的正向变构调节可预防PS19小鼠模型中神经元萎缩和认知功能下降，且独立于tau缠结的积累。	Dharavath, R. N.	PDF	N/A	Positive Allosteric Modulation of the α5-GABAA receptors prevents neuronal atrophy and cognitive decline independently of tau tangle accumulation in the PS19 mouse model
在额下皮质中，解剖学上不同的区域受到任务和阅读技能的调节。	Stone, H. L.	PDF	N/A	Anatomically distinct regions in the inferior frontal cortex are modulated by task and reading skill
肾上腺素能C1神经元通过投射到中脑导水管周围灰质（PAG）来增强焦虑。	Fernandez-Pena, C.	PDF	N/A	Adrenergic C1 neurons enhance anxiety via projections to PAG
辅助剂对疫苗诱导的体液免疫反应和保护作用的影响：在鼻腔和生殖道定植病原性奈瑟菌的临床前模型中	Islam, E. A.	PDF	N/A	Adjuvant-dependent impacts on vaccine-induced humoral responses and protection in preclinical models of nasal and genital colonization by pathogenic Neisseria
体外构建巨噬细胞极化模型：以Raw 264.7巨噬细胞系为例	Yee, K. K.	PDF	N/A	An in vitro modelling of resolving macrophage with Raw 264.7 macrophage cell line
小鼠心脏中伴侣复合体的年龄相关变化	Bhat, P. D.	PDF	N/A	Age-dependent Changes in a Chaperone Complex in the Mouse Heart
全球蛋白质组学揭示了电离辐射诱导的亚细胞特异性抗铁死亡反应	Christopher, J. A.	PDF	N/A	Global proteomics indicates subcellular-specific anti-ferroptotic responses to ionizing radiation
有丝分裂驱动蛋白-5是轴突生长的动态刹车	Lu, W.	PDF	N/A	'Mitotic' kinesin-5 is a dynamic brake for axonal growth
钙网蛋白在蝴蝶翅膀鳞片细胞内的角质层沉积和横梁形成过程中是必需的。	Hong, R.	PDF	N/A	Calreticulin is required for cuticle deposition and trabeculae formation inside butterfly wing scale cells
PSMA特异性CAR改造的巨噬细胞用于前列腺癌治疗	Xu, Y.	PDF	N/A	PSMA-specific CAR-engineered macrophages for therapy of prostate cancer
肌球蛋白簇动力学决定上皮伤口环收缩	Bhat, A.	PDF	N/A	Myosin cluster dynamics determines epithelial wound ring constriction
无参数清晰图像反卷积（CLID）技术用于单帧活细胞超分辨率成像	Xue, F.	PDF	N/A	Parameter-free clear image deconvolution (CLID) technique for single-frame live-cell super-resolution imaging
痛风药物抑制尿酸转运蛋白URAT1的分子基础	Suo, Y.	PDF	N/A	Molecular basis of the urate transporter URAT1 inhibition by gout drugs
# BioRxiv 2024-09-11 Papers

标题	作者	PDF链接	代码仓库	Title
紫色叶背植物：气孔分布指标的资源库。	Almeida Filho, H. A.	PDF	N/A	Plants with purple abaxial leaves: A repository of metrics from stomata distribution.
来自PRPF31+/- hiPSC-RPE的细胞外囊泡中的RNA含量显示出作为视网膜变性生物标志物的潜力	Getachew, H.	PDF	N/A	The RNA Content of Extracellular Vesicles from PRPF31+/- hiPSC-RPE Show Potential as Biomarkers of Retinal Degeneration
隔离和种间相互作用在产生岛屿哺乳动物辐射的功能多样性中的作用	Nations, J. A.	PDF	N/A	The roles of isolation and interspecific interaction in generating the functional diversity of an insular mammal radiation
骨骼肌和神经肌肉执行器的Hill型模型：系统性综述	Caillet, A. H.	PDF	N/A	Hill-type models of skeletal muscle and neuromuscular actuators: a systematic review
基于抑制的视网膜神经节细胞模型：跨物种和刺激的比较与泛化	Shahidi, N.	PDF	N/A	Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli
大脑中的视觉同质性计算能够解决基于属性的视觉任务。	Jacob, G.	PDF	N/A	Visual homogeneity computations in the brain enablesolving property-based visual tasks
重温扫视遗漏：扫视引发的模糊是什么样子的	Schweitzer, R.	PDF	N/A	Saccadic omission revisited: What saccade-induced smear looks like
黄瓜（Cucumis sativus）激酶组：鉴定、注释及对白粉病感染的表达模式	Costa, F. C. L.	PDF	N/A	The Cucumis sativus kinome: Identification, annotation, and expression patterns in response to powdery mildew infection
快速细胞内酸化是一种由褐飞虱对抗的新型植物防御反应。	Jiang, Y.	PDF	N/A	Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper
注意通过调整锐化来调节人类对物体的视觉反应	Doostani, N.	PDF	N/A	Attention Modulates Human Visual Responses to Objects by Tuning Sharpening
改善焦虑研究：通过多状态总结测量的新方法揭示特质焦虑	Varga, Z. K.	PDF	N/A	Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states
多拷贝基因系统中由遗传漂变驱动的极快进化的悖论	Wang, X.	PDF	N/A	The paradox of extremely fast evolution driven by genetic drift in multi-copy gene systems
M3NetFlow：一种用于综合多组学数据分析的新型多尺度多跳图AI模型	Zhang, H.	PDF	N/A	M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis
新生成的成年神经元可保护小鼠免受癫痫的侵害。	Jain, S.	PDF	N/A	Increasing adult-born neurons protects mice from epilepsy.
如果……会怎样？小脑皮层颗粒层的计算解剖学	Gilbert, M.	PDF	N/A	What if...? Computational anatomy in the granular layer of the cerebellar cortex
铁剥夺吡咯啶对人类机会性病原体的抗菌活性	Vollenweider, V.	PDF	N/A	Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens
STING-CASM-GABARAP通路在溶酶体上激活LRRK2	Bentley-DeSousa, A.	PDF	N/A	A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes
植物转录因子结合区域发现中的计算方法综合分析	Jyoti,	PDF	N/A	Comprehensive analysis of computational approaches in plant transcription factors binding regions discovery
糖皮质激素时间药理学揭示了心肌细胞特异性GR-KLF15轴在心脏葡萄糖代谢中的新靶点	El Abdellaoui-Soussi, F.	PDF	N/A	Glucocorticoid chrono-pharmacology unveils novel targets for the cardiomyocyte-specific GR-KLF15 axis in cardiac glucose metabolism
PMP22通过其跨膜结构域与MPZ相关联，破坏这种相互作用会导致功能丧失表型，类似于与压力性麻痹易感性相关的遗传性神经病变（HNPP）。	Pashkova, N.	PDF	N/A	PMP22 associates with MPZ via their transmembrane domains and disrupting this interaction causes a loss-of-function phenotype similar to hereditary neuropathy associated with liability to pressure palsies (HNPP).
蓝斑微胶质细胞在女性应激反应中的功能作用	Smiley, C. E.	PDF	N/A	The functional role of locus coeruleus microglia in the female stress response
将梯度提升树应用于QTL定位，并结合Shapley加性解释	Ishibashi, T.	PDF	N/A	Applying gradient tree boosting to QTL mapping with Shapley additive explanations
NF1相关周围神经鞘瘤的综合基因组分析：更新后的生物样本库数据集	Banerjee, J.	PDF	N/A	Integrated genomic analysis of NF1-associated peripheral nerve sheath tumors: an updated biorepository dataset
猴子外侧前额叶皮层的不同亚区对抽象序列及其组成部分有反应。	Rodriguez, N. Y.	PDF	N/A	Different subregions of monkey lateral prefrontal cortex respond to abstract sequences and their components
苔藓动物中两侧对称动物基因组的融合、分裂与重组	Lewin, T. D.	PDF	N/A	Fusion, fission, and scrambling of the bilaterian genome in Bryozoa
DC1域蛋白Vacuoleless Gametophytes调控拟南芥雄蕊发育	Amigo, N. L.	PDF	N/A	The DC1 domain protein Vacuoleless Gametophytes regulates stamen development in Arabidopsis
欧洲濒危睡鼠的单倍体型解析基因组与群体基因组学研究	Byerly, P.	PDF	N/A	Haplotype-resolved genome and population genomics of the threatened garden dormouse in Europe
Syngap1 调控小鼠听觉皮层中 Parvalbumin 阳性中间神经元的突触驱动和膜兴奋性。	Francavilla, R.	PDF	N/A	Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
MIXL1在人诱导多能干细胞内胚层分化中的激活	Osteil, P.	PDF	N/A	MIXL1 Activation in Endoderm Differentiation ofHuman Induced Pluripotent Stem Cells
FLIGHTED：从噪声高吞吐量实验数据中推断适应性景观	Sundar, V.	PDF	N/A	FLIGHTED: Inferring Fitness Landscapes from Noisy High-Throughput Experimental Data
噪声模式有助于在噪声中听清声音。	Hicks, J. M.	PDF	N/A	Noise schemas aid hearing in noise
系统发育对从蛋白质序列数据推断功能区域的影响	Dietler, N.	PDF	N/A	Impact of phylogeny on the inference of functional sectors from protein sequence data
模拟研究空间在药物敏感与耐药癌细胞相互作用中的作用	Pugh, K.	PDF	N/A	Simulations probe the role of space in the interplay between drug-sensitive and drug-resistant cancer cells
ChatNT：一种用于DNA、RNA和蛋白质任务的多模态对话代理	Richard, G.	PDF	N/A	ChatNT: A Multimodal Conversational Agent for DNA, RNA and Protein Tasks
海洋深处的光波：对三种海笔（Pennatuloidea，Octocorallia，Anthozoa）发光系统的洞察	Duchatelet, L.	PDF	N/A	Waves of light at the bottom of the ocean: insights into the luminous systems of three sea pens (Pennatuloidea, Octocorallia, Anthozoa)
基因组语言模型是否足够？探索基因组语言模型在蛋白质下游任务中的应用	Boshar, S.	PDF	N/A	Are Genomic Language Models All You Need? Exploring Genomic Language Models on Protein Downstream Tasks
SaprotHub：让蛋白质建模变得触手可及，惠及所有生物学家	Su, J.	PDF	N/A	SaprotHub: Making Protein Modeling Accessible to All Biologists
幼鼠卵巢中的三波卵泡发育	Yin, Q.	PDF	N/A	Three waves of ovarian follicles in juvenile mice
BRCA1与非典型DNA结构的相互作用：对基因组维持和疾病机制的见解	Lowran, K.	PDF	N/A	BRCA1 Interaction with Non-Canonical DNA Structures: Insights into Genome Maintenance and Disease Mechanisms
ProTrek：通过三模态对比学习探索蛋白质宇宙	Su, J.	PDF	N/A	ProTrek: Navigating the Protein Universe through Tri-Modal Contrastive Learning
组成性活化受体ADGRA3信号传导诱导脂肪组织产热	Zhao, Z.	PDF	N/A	Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis
基于机器学习的多基因预测模型用于鼻咽癌辐射敏感性	Li, K.	PDF	N/A	A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning
一个调控水稻鞘细胞表达的转录因子五重奏	Hua, L.	PDF	N/A	A transcription factor quintet orchestrating bundle sheath expression in rice
第三种情景记忆：情景熟悉度是一个与项目熟悉度和回忆不同的过程。	Addante, R. J.	PDF	N/A	A third kind of episodic memory: Context familiarity is a distinct process from item familiarity and recollection
欧洲外生菌根担子菌纲真菌中宿主选择影响其孢子体积的估算	Izumi, H.	PDF	N/A	Host selection in European ectomycorrhizal Basidiomycetes affects their estimated spore volumes
通过AI驱动的多参数理性设计增强Taq聚合酶的逆转录酶功能	Tomilova, Y. E.	PDF	N/A	Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design
基质硬度通过Piezo1介导的TTR活性调节神经元的成熟	Kreysing, E.	PDF	N/A	Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity
强迫症中的认知序列受到前额叶皮层渐进活动的支持，并由症状严重程度介导。	Doyle, H.	PDF	N/A	Cognitive sequences in obsessive-compulsive disorder are supported by frontal cortex ramping activity and mediated by symptom severity
质粒病毒维持使细菌种群从感染中恢复并实现病毒-细菌共存	Sanchez-Martinez, R.	PDF	N/A	Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence
CA3中的选择性抑制：通过异突触可塑性实现稳定模式完成的机制	Kim, G.	PDF	N/A	Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity
敬畏在人类行为和大脑皮层中被描述为一种矛盾的体验：综合虚拟现实-脑电图研究	Yi, J.	PDF	N/A	Awe is characterized as an ambivalent experience in the human behavior and cortex: integrated virtual reality-electroencephalogram study
发育调控的微外显子缺失对斑马鱼幼体大脑形态和功能的影响微乎其微	Calhoun, C. C. S.	PDF	N/A	Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function
稻黄斑驳病毒的多模态传播：谷物、贸易与战争的历史与地理溯源	Ndikumana, I.	PDF	N/A	Grains, trade and war in the multimodal transmission of Rice yellow mottle virus: an historical and phylogeographical retrospective
鞭毛滑动运动：一种新型的独立于推进的机制，用于沙门氏菌和大肠杆菌的表面迁移	Panich, J.	PDF	N/A	Swashing motility: A novel propulsion-independent mechanism for surface migration in Salmonella and E. coli
编排不可能的化学反应：B12依赖型甲硫氨酸合成酶催化编排的结构快照	Mendoza, J.	PDF	N/A	Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography
通过尿素激活酶揭示构象动力学与底物结合之间的相互作用：一项单分子FRET研究	Scheerer, D.	PDF	N/A	Enzyme activation by urea reveals the interplay between conformational dynamics and substrate binding:a single-molecule FRET study
肺炎支原体必需脂蛋白的结构表征	Keles, I.	PDF	N/A	Structural characterization of an essential lipoprotein of Mycoplasma pneumoniae
在属Mus中TCRα和TCRβ位点的独特进化	Peters, M. A.	PDF	N/A	Distinct evolution at TCRα and TCRβ loci in the genus Mus
哺乳动物大脑的体内光学透明化	Talei Franzesi, G.	PDF	N/A	In Vivo Optical Clearing of Mammalian Brain
小说性Pannexin 1异构体在癌症中增加	O'Donnell, B. L.	PDF	N/A	Novel Pannexin 1 isoform is increased in cancer
小鼠属中不同CD8+ α/β-TCR库的遗传决定因素	Peters, M. A.	PDF	N/A	Genetic determinants of distinct CD8+ α/β-TCR repertoires in the genus Mus
在健康小鼠中使用Semaglutide给药改变了与压力和动机相关的行为	Moreno, A.	PDF	N/A	Semaglutide Administration in Healthy Mice Alters Behaviour Related to Stress and Motivation
维多利亚州考拉中重组考拉逆转录病毒（recKoRV）的高频率检测表明KoRV的历史性整合	Zheng, L.	PDF	N/A	A High Frequency of Detection of Recombinant Koala Retrovirus (recKoRV) in Victorian Koalas Suggests Historic Integration of KoRV
在狒狒群体中，早期哺乳期的同步性高预示着婴儿死亡率增加。	Winans, J. C.	PDF	N/A	High early lactational synchrony within baboon groups predicts increased infant mortality
可扩展的从元细胞中识别谱系特异性基因调控网络的方法：NetID	Wang, W.	PDF	N/A	Scalable identification of lineage-specific gene regulatory networks from metacells with NetID
斑马鱼ebf3a突变体中感觉系统和大脑皮层的发育障碍	Dang, N. D. P.	PDF	N/A	Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant
斑马鱼ebf3a突变体中感觉系统和大脑小脑的发育障碍	Dang, N. D. P.	PDF	N/A	Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant
在啮齿动物前额叶皮层第2/3层的反复兴奋性突触中，短期易化现象的基础是易于释放的突触囊泡池的逐步充盈。	Shin, J.	PDF	N/A	Progressive overfilling of readily releasable pool underlies short-term facilitation at recurrent excitatory synapses in layer 2/3 of the rat prefrontal cortex
遗漏响应神经元在听觉皮层中编码负预测误差和概率	Yaron, A.	PDF	N/A	Omission-responsive neurons encode negative prediction error and probability in the auditory cortex
早期生活神经影像学：皮质区域划分在发育过程中的普遍性	Tu, J.	PDF	N/A	Early Life Neuroimaging: The Generalizability of Cortical Area Parcellations Across Development
静默视觉言语中的眼球运动追踪未听到的声学信号，并与听觉经验相关联	Benz, K.	PDF	N/A	Eye Movements in Silent Visual Speech track Unheard Acoustic Signals and Relate to Hearing Experience
基于外部奖励的技能学习对运动可塑性的影响	Yadav, G.	PDF	N/A	Effects Of Extrinsic Reward Based Skill Learning On Motor Plasticity
Shox2对于正常丘脑梭形波功能是必需的。	Febbo, I. G.	PDF	N/A	Shox2 is necessary for normal thalamic spindle function
课程学习：任务复杂度的顺序获取增强了神经元的辨别能力	Shujah, M.	PDF	N/A	Curriculum Learning: sequential acquisition of task complexity enhances neuronal discriminability
多表位免疫捕获亨廷顿蛋白揭示纹状体选择性分子特征	Justice, J. L.	PDF	N/A	Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures
外侧缰核神经元的厌恶编码与行为状态调节	Zouridis, I. S.	PDF	N/A	Aversion encoding and behavioral state modulation of lateral habenula neurons
通过扫视采样进行物体识别的时空证据积累	Zheng, Z.	PDF	N/A	Spatiotemporal evidence accumulation through saccadic sampling for object recognition
调控因子的反相聚集塑造基因爆发	Li, B.	PDF	N/A	Anti-phase clustering of regulatory factors shapes gene bursting
调控因子的反相聚集塑造了基因爆发	Li, B.	PDF	N/A	Anti-phase clustering of regulatory factors shapes gene bursting
自然选择作用于复杂性状，阻碍了多基因评分在古代样本中的预测准确性。	Anorve-Garibay, V.	PDF	N/A	Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples
高覆盖率、大规模并行单细胞基因组测序与CAP-seq技术	Li, M.	PDF	N/A	High-coverage, massively parallel sequencing of single-cell genomes with CAP-seq
缺氧阻碍了颅神经嵴细胞向与颅面发育相关衍生物的分化	Schmid, T.	PDF	N/A	Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development
多祖先全基因组关联研究揭示了与人类LINE-1和Alu拷贝数变异相关的位点	Bravo, J. I.	PDF	N/A	Multi-ancestry GWAS reveals loci linked to human variation in LINE-1- and Alu-copy numbers
EHZ2抑制增强了铂类化疗在侵袭性前列腺癌变异中的活性	Latarani, M.	PDF	N/A	EHZ2 inhibition enhances the activity of platinum chemotherapy in aggressive variant prostate cancer
弥合灰质微观结构与功能连接组之间的差距：早产儿与足月婴儿的多模态磁共振成像研究	Gondova, A.	PDF	N/A	Bridging the gap between grey-matter microstructural and functional connectomes: A multi-modal MRI study in preterm and full-term infants
通过视觉伽马振荡测量兴奋-抑制平衡的神经发育轨迹	Rhodes, N.	PDF	N/A	Measuring the neurodevelopmental trajectory of excitatory-inhibitory balance via visual gamma oscillations
如果……？小脑微区中的计算解剖学，小脑网络的中层	Gilbert, M.	PDF	N/A	What if...? Computational anatomy in the cerebellar microzone, the middle layer of the cerebellar network
裂解酵母SUMO靶向泛素连接酶Slx8在功能上与核周聚集的着丝粒以及沉默的交配型区域相关联。	Chakraborty, S.	PDF	N/A	The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery
学习空间转录组学中与表型相关的特征：PASSAGE方法	Guo, C.-K.	PDF	N/A	Learning phenotype associated signature in spatial transcriptomics with PASSAGE
通过固定化白腐菌混合菌株酶解降解氯酚废水	Liu, H.	PDF	N/A	Enzymatic Degrading Chlorophenol Wastewater by Mixed Strains of Immobilized White Rot Fungi
结蛋白突变在心肌成纤维细胞中通过beclin-1调节导致TGFβ1介导的病理性纤维化，这是结蛋白心肌病中的一个过程。	Chen, H. V.	PDF	N/A	Desmoplakin mutations in cardiac fibroblasts cause TGF?1-mediated pathological fibrogenesis in desmoplakin cardiomyopathy via beclin-1 regulation
自然杂草种子捕食者能减少20%的谷物田中因杂草导致的作物产量损失。	Muneret, L.	PDF	N/A	Natural weed seed predators reduce crop yield loss due to weeds by 20% in cereal fields
在7特斯拉下使用优化的点状编码时间减少与径向采集（PETRA）序列进行超短T2*成像，分别在标准和扩展回波时间下进行。	Lockard, C. A.	PDF	N/A	Ultrashort-T2* mapping at 7 tesla using an optimized pointwise encoding time reduction with radial acquisition (PETRA) sequence at standard and extended echo times
胆管癌细胞系中的线粒体基因组改变	Faipan, A.	PDF	N/A	Mitochondrial genomic alterations in cholangiocarcinoma cell lines
Castleman病空间和单细胞图谱揭示关键基质细胞类型和细胞因子通路	Smith, D.	PDF	N/A	Spatial and Single Cell Mapping of Castleman Disease Reveals Key Stromal Cell Types and Cytokine Pathways
烟酰胺核苷：通过上调烟酰胺磷酸核糖基转移酶介导的NAD水平，有望成为治疗心肌梗死诱导的急性肾损伤的有效疗法	HABEICHI, N. J.	PDF	N/A	Nicotinamide riboside: A promising therapy for MI-induced acute kidney injury by upregulating nicotinamide phosphoribosyltransferase-mediated NAD levels
鼻内给予丹曲林纳米颗粒抑制脂多糖诱导的小鼠抑郁和焦虑行为	Liu, J.	PDF	N/A	Intranasal dantrolene nanoparticles inhibit lipopolysaccharide-induced depression and anxiety behavior in mice
光系统II释放氧气后，能够进展到S1状态的S0状态的重整动力学	Boussac, A.	PDF	N/A	Kinetics of reformation of an S0 state capable of progressing to an S1 state after the O2 release by Photosystem II
通过Pluronic辅助的同轴3D生物打印技术制备生物工程束状骨骼肌生物执行器	Fuentes, J.	PDF	N/A	Bioengineering Fascicle-like Skeletal Muscle Bioactuators via Pluronic-Assisted Co-axial 3D Bioprinting
靶向CXCR4与-Pentixather联合使用显著提高小细胞肺癌患者的总体生存率	Christensen, K. A.	PDF	N/A	Targeting CXCR4 with -Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer
EyaHOST是一种模块化的遗传系统，用于研究果蝇（Drosophila melanogaster）中细胞间及肿瘤与宿主之间的相互作用。	Teles-Reis, J.	PDF	N/A	EyaHOST a modular genetic system for investigation of intercellular and tumor-host interactions in Drosophila melanogaster
学习阅读将语音转换为语音图形表示：来自一项失匹配负波研究的证据	Pattamadilok, C.	PDF	N/A	Learning to read transforms phonological into phonographic representations: Evidence from a Mismatch Negativity study
具身主体感代理的神经关联	Regev Krugwasser, A.	PDF	N/A	Neural Correlates of the Embodied Sense of Agency
治疗期间癌症拦截：利用生长动力学创建一个连续变量以评估疾病反应	Zhou, M.	PDF	N/A	Cancer Interception During Treatment: Using Growth Kinetics to Create a Continuous Variable for Assessing Disease Response
KIF5A 调控轴突修复以及 SFPQ 颗粒和线粒体在人类运动神经元中的时间依赖性轴突运输	Guerra San Juan, I.	PDF	N/A	KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons
瞬时大脑状态参与度的变化在个体发育过程中有所不同，并对执行功能的个体差异产生影响。	Ye, J.	PDF	N/A	Variation in moment-to-moment brain state engagement changes across development and contributes to individual differences in executive function
通过工程化锌指抑制剂对SCN9A进行强效且特异性的抑制，用于治疗神经性疼痛	samie, m.	PDF	N/A	Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain
早期NK细胞和T细胞功能障碍标志着肥胖和健康体重患者登革热病情的加重	Gregorova, M.	PDF	N/A	Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight
在碳青霉烯酶的适应性进化过程中，上位效应推动了多个性状的快速分化。	Dabos, L.	PDF	N/A	Epistasis drives rapid divergence across multiple traits during the adaptive evolution of a carbapenemase
通过宿主启动的专性外共生和代谢抑制实现早期真核生物起源	Krishnan, N.	PDF	N/A	Early eukaryogenesis by host-initiated obligate ectosymbiosis and metabolic inhibition
癌症-免疫共进化由抗原突变积累所决定	Wang, L.	PDF	N/A	Cancer-immune coevolution dictated by antigenic mutation accumulation
通过适应性实验揭示的真菌交配型染色体中的隐性负载	Guyot, L.	PDF	N/A	Sheltered load in fungal mating-type chromosomes revealed by fitness experiments
微生物群驱动黄粉虫感染结果的性别二态性	Seal, S.	PDF	N/A	Microbiota drives the sexually dimorphic infection outcomes in mealworm beetles
EpipwR：针对连续结果的EWAS的高效功率分析	Barth, J. P.	PDF	N/A	EpipwR: Efficient Power Analysis for EWAS withContinuous Outcomes
一种模拟人类妊娠期胎盘暴露于环境金属的生物工程模型	Fattahi, P.	PDF	N/A	A bioengineered model of human placental exposure to environmental metals during pregnancy
CryoTEN：利用Transformer高效增强冷冻电镜密度图	Selvaraj, J.	PDF	N/A	CryoTEN: Efficiently Enhancing Cryo-EM DensityMaps Using Transformers
基于结构的计算分析：胰岛素受体与胰岛素抑制受体之间的相互作用	Li, V.	PDF	N/A	Structure-Based Computational Analysis of Interactions between Insulin Receptor and Insulin Inhibitory Receptor
发现来自印度南部的一种新的地下鳗鲶新种	RAMANATHAN, S. K.	PDF	N/A	Discovery of a new species of subterranean eel loach from southern India
味蕾中的死亡：死亡味觉细胞的形态特征及I型细胞的吞噬作用	Wilson, C. E.	PDF	N/A	Death in the taste bud: Morphological features of dying taste cells and engulfment by Type I cells
神经递质对结构-功能耦合的贡献：来自灰质体积（GMV）和脑熵（BEN）的证据	Song, D.	PDF	N/A	Neurotransmitters Contribute Structure-Function Coupling: Evidence from Grey Matter Volume (GMV) and Brain Entropy (BEN)
模拟CD8 T细胞衰竭：一种综合方法	Manrique-Rincon, A. J.	PDF	N/A	Simulating CD8 T Cell Exhaustion: A Comprehensive Approach
关于前向采样方案密度的一个接近紧的下界	Kille, B.	PDF	N/A	A near-tight lower bound on the density of forward sampling schemes
小鼠多巴胺能穹窿下区神经元的全脑投射	Bono, B. S.	PDF	N/A	Brain-wide projections of mouse dopaminergic zona incerta neurons
单分子脂质生物传感器减轻内源效应蛋白的抑制作用	Holmes, V.	PDF	N/A	Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins
优化扩展显微技术揭示了非洲爪蟾卵提取物中物种特异性的纺锤体微管组织	Guilloux, G.	PDF	N/A	Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts
蛋白质相互作用基序的全蛋白质组依赖性图谱	Ambjoern, S.	PDF	N/A	A proteome-wide dependency map of protein interaction motifs
造血Tet2失活增强了免疫检查点阻断疗法的反应	Vanner, R. J.	PDF	N/A	Hematopoietic Tet2 inactivation enhances the response to checkpoint blockade immunotherapy
卵巢癌中与年龄相关的脂质代谢调控	Feng, J.	PDF	N/A	Regulation of Age-Related Lipid Metabolism in Ovarian Cancer
EB-SUN，果蝇中一种新的微管正端追踪蛋白。	Kim, S. K.	PDF	N/A	EB-SUN, a New Microtubule Plus-End Tracking Protein in Drosophila.
衰老小鼠各组织的自噬作用	Carosi, J. M.	PDF	N/A	Autophagy across tissues of aging mice
具有截短的Cas12a结合序列的单链HDR模板提高了在原代人T细胞中的敲入效率	Nitulescu, A.-M.	PDF	N/A	Single-stranded HDR templates with truncated Cas12a binding sequences improve knock-in efficiencies in primary human T cells
一种在鲍曼不动杆菌中协调肽聚糖周转并激活细胞分裂酰胺酶的保守枢纽蛋白	Simpson, B. W.	PDF	N/A	A conserved hub protein for coordinating peptidoglycan turnover that activates cell division amidases in Acinetobacter baumannii
一种基于微孔板读取器的高通量方法，用于在没有流式细胞术的情况下监测体外HIV潜伏逆转	Nkwelle, C. E.	PDF	N/A	A high-throughput, microplate reader-based method to monitor in vitro HIV latency reversal in the absence of flow cytometry
鉴定影响CRISPR相关转座酶的蛋白质以增强基因组编辑	Song, L.	PDF	N/A	Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing
PathMHC：一种工作流程，用于在疫苗靶点识别的发现性免疫肽组学实验中选择性靶向病原体衍生的MHC肽段	Leddy, O.	PDF	N/A	PathMHC: a workflow to selectively target pathogen-derived MHC peptides in discovery immunopeptidomics experiments for vaccine target identification
延伸因子P调控沙门氏菌抗生素抗性基因的核糖体移码	Baek, S.	PDF	N/A	Elongation factor P controls ribosomal frameshift of a Salmonella antimicrobial resistance gene
利用果聚糖的γ-变形菌中的SusC/D样蛋白	Zuehlke, M.-K.	PDF	N/A	SusC/D-like proteins in Gammaproteobacteria that utilize fructans
IGF1R在肺炎球菌性肺炎中具有保护作用	Felten, M.	PDF	N/A	IGF1R is protective in pneumococcal pneumonia
SRY-Box转录因子9通过解除转录抑制因子CCAAT/增强子结合蛋白β的抑制作用，调控3'-磷酸腺苷5'-磷酸硫酸合成酶2 mRNA的表达。	Liu, C.	PDF	N/A	SRY-Box Transcription Factor 9 regulates 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2 mRNA expression through derepression of the transcriptional repressor, CCAAT/enhancer-binding protein beta
基因组方法研究克雷伯氏肺炎杆菌临床分离株中CRISPR/Cas系统与多药耐药性之间的关系	Owaid, H. A.	PDF	N/A	Genomic approach to studying the relationship between the CRISPR/Cas system and multidrug resistance in clinical isolates of Klebsiella pneumoniae
通过化学标记实现细胞蛋白激酶活性的分子记录	Sun, D.-e.	PDF	N/A	Molecular recording of cellular protein kinase activity with chemical labeling
单个远端突变通过稳定PET结合增强已知PETase的活性	Fu, X.	PDF	N/A	Single Distal Mutation Enhances Activity of known PETases via Stabilisation of PET-binding
CRISPR编辑影响甲型流感病毒感染的候选宿主因子	Kyawe, P. P.	PDF	N/A	CRISPR editing of candidate host factors that impact influenza A virus infection
组蛋白甲基转移酶DOT1B对于利什曼原虫（Leishmania mexicana）的阶段分化和巨噬细胞感染并非必需。	Eisenhuth, N.	PDF	N/A	The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection in Leishmania mexicana
父母照顾对毒蛙皮肤微生物群落组成的影响	Fischer, M.-T.	PDF	N/A	Effects of parental care on skin microbial community composition in poison frogs
利用病毒RNA加工的阿喀琉斯之踵开发新型抗病毒药物	Zahedi Amiri, A.	PDF	N/A	Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals
在磷酸盐限制条件下，阿米诺脂的生物合成促进了鲍曼不动杆菌对粘菌素的耐药性。	Olea-Ozuna, R. J.	PDF	N/A	Aminolipid biosynthesis in response to phosphate limitation promotes colistin tolerance in Acinetobacter baumannii
一项针对挪威肺炎克雷伯菌的全基因组“一个健康”研究揭示了重叠的菌群，但近期在不同宿主间的传播事件较少。	Hetland, M. A. K.	PDF	N/A	A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs
共生体的丧失和获得，而非共同多样化，塑造了蜜蜂肠道微生物群的多样性和功能。	Prasad, A.	PDF	N/A	Symbiont loss and gain, rather than co-diversification shapes honeybee gut microbiota diversity and function
预防脑膜炎奈瑟菌鼻咽部定植依赖于抗体调理和中性粒细胞的吞噬作用。	Currie, E. G.	PDF	N/A	Protection against Neisseria meningitidis nasopharyngeal colonization relies on antibody opsonization and phagocytosis by neutrophils
抗生素诱导的形态变化增强噬菌体捕食：结构化环境中噬菌斑形成的数学模型	Bulssico, J.	PDF	N/A	Antibiotic-Induced Morphological Changes Enhance Phage Predation: A Mathematical Model of Plaque Formation in Structured Environments
flt1失活通过增强内皮细胞活性并限制纤维化反应，促进斑马鱼心脏再生。	Wang, Z.	PDF	N/A	flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response
多重纳米孔扩增子测序用于区分抗疟药物试验中的复发与新感染	Holzschuh, A.	PDF	N/A	Multiplexed nanopore amplicon sequencing to distinguish recrudescence from new infection in antimalarial drug trials
工程变体AAV滴定中热稳定性的作用	Zin, E. A.	PDF	N/A	The Role of Thermal Stability in AAV Titration of Engineered Variants
HIV Vpr通过激活一种核仁特异性的ATR途径来降解核仁应激传感器CCDC137	Nisson, K. A.	PDF	N/A	HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137
跨膜糖蛋白Gpnmb在斑马鱼心脏再生过程中的免疫和纤维化反应中是必需的。	Gupta, S.	PDF	N/A	The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration
RNA解旋酶HrpA在E. coli中解救碰撞的核糖体	Campbell, A.	PDF	N/A	The RNA helicase HrpA rescues collided ribosomes in E. coli
尿酸通过天然人URAT1转运的分子机制及其被抗痛风药物抑制的机制	Wu, C.	PDF	N/A	Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs
不受海马体尖波涟漪调节的前额叶皮质内侧神经元参与空间调谐及即将做出的选择信号传递。	den Bakker, H.	PDF	N/A	Neurons in the medial prefrontal cortex that are not modulated by hippocampal sharp-wave ripples are involved in spatial tuning and signaling upcoming choice.
小脑-丘脑神经元在学习及小鼠运动技能离线巩固中的多重功能	Varani, A.	PDF	N/A	Multiple Functions of Cerebello-Thalamic Neurons in Learning and Offline Consolidation of a Motor Skill in mice.
听觉皮层结构与阅读技能的代际传递	Kepinska, O.	PDF	N/A	Intergenerational transmission of the structure of the auditory cortex and reading skills
斑马鱼模型揭示人类基因SRGAP2在神经胶质细胞和视觉系统发育中的新功能	Uribe-Salazar, J. M.	PDF	N/A	Zebrafish models of human-duplicated gene SRGAP2 reveal novel functions in microglia and visual system development
高数据率大分子晶体学（HDRMX）的大规模压缩：对衍射数据及后续结构分析的影响	Bernstein, H. J.	PDF	N/A	Massive Compression for High Data Rate Macromolecular Crystallography (HDRMX): Impact on Diffraction Data and Subsequent Structural Analysis
NAPE-PLD基因的缺失在小鼠中引发了情境依赖性的焦虑样行为、应激反应及下丘脑-垂体-肾上腺轴功能的失调。	Woodward, T. J.	PDF	N/A	Genetic deletion of NAPE-PLD induces context-dependent dysregulation of anxiety-like behaviors, stress responsiveness, and HPA-axis functionality in mice
海马苔藓纤维突触处突触前易化的废除影响神经元集合活动和空间记忆	Marneffe, C.	PDF	N/A	Abrogation of presynaptic facilitation at hippocampal mossy fiber synapses impacts neural ensemble activity and spatial memory
玩耍行为的转录组在幼年大鼠内侧杏仁核中表现出性别偏向：抑制性神经元的作用	Marquardt, A. E.	PDF	N/A	The transcriptome of playfulness is sex-biased in the juvenile rat medial amygdala: a role for inhibitory neurons
中性粒细胞特异性STING在心肌缺血/再灌注损伤中的心脏保护作用	Brockman, M. L.	PDF	N/A	The Cardioprotective Role of Neutrophil-Specific STING in Myocardial Ischemia/Reperfusion Injury
Axin1和Axin2调控WNT信号通路，以促进不同的中胚层发育程序	Hernandez-Martinez, R.	PDF	N/A	Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs
IgSF蛋白DIP-α和Dpr10的关键亲和窗口对于适当的运动神经元树突化是必需的。	Lopez, D.	PDF	N/A	A critical affinity window for IgSF proteins DIP-α and Dpr10 is required for proper motor neuron arborization
将环斑海豹的觅食行为与环境变化联系起来	Nykänen, M.	PDF	N/A	Linking ringed seal foraging behaviour to environmental variability
广泛存在的自然变异人类外显子有助于遗传学解释	Jacobs, H.	PDF	N/A	Widespread naturally variable human exons aid genetic interpretation
# BioRxiv 2024-09-10 Papers

标题	作者	PDF链接	代码仓库	Title
神经元中异染色质长期丧失后，伴随胶质细胞反应和认知能力下降	Newman, A. G.	PDF	N/A	Glial Reactivity and Cognitive Decline Follow Chronic Heterochromatin Loss in Neurons
intSDM：一个用于构建可重复性工作流的综合物种分布模型领域的R包	Mostert, P. S.	PDF	N/A	intSDM : an R package for building a reproducible workflow for the field of integrated species distribution models
进化上多样化的真菌游动孢子展现出特定的游泳模式，这些模式与其超微结构密切相关。	Galindo, L. J.	PDF	N/A	Evolutionarily diverse fungal zoospores show contrasting swimming patterns specific to ultrastructure
海马体中扩展记忆表征的形成	Vaidya, S. P.	PDF	N/A	The formation of an expanding memory representation in the hippocampus
突触可塑性的结构影响：突触前连接在E/I共调谐出现中的作用	Giannakakis, E.	PDF	N/A	Structural influences on synaptic plasticity: the role of presynaptic connectivity in the emergence of E/I co-tuning
内源性病毒元件构成了个性化癌症疫苗抗原的补充来源。	Garde, C.	PDF	N/A	Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines
植入前胚胎放大了压力诱导的精子衍生miRNA含量的变化，以介导跨代表观遗传继承	Champroux, A.	PDF	N/A	Preimplantation Embryos Amplify Stress-Induced Changes in Sperm-Derived miRNA Content to Mediate Transgenerational Epigenetic Inheritance
在人类细胞中发现微小RNA衍生的RNA和蛋白质	Huang, X.	PDF	N/A	Discovery of microsized RNA-derived RNAs and proteins in human cells
改善焦虑研究：通过多状态总结测量的新方法揭示特质焦虑	Varga, Z. K.	PDF	N/A	Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states
脑膜炎症的空间转录组学揭示了邻近脑实质中的炎症基因特征	Gadani, S.	PDF	N/A	Spatial Transcriptomics of Meningeal Inflammation Reveals Inflammatory Gene Signatures in Adjacent Brain Parenchyma
硒代半胱氨酸tRNA甲基化促进黑色素瘤转移中氧化应激的抵抗力	Nease, L. A.	PDF	N/A	Selenocysteine tRNA methylation promotes oxidative stress resistance in melanoma metastasis
在运动执行和运动规划过程中，控制策略可以根据任务需求进行调整。	Orban de Xivry, J.-J.	PDF	N/A	A control policy can be adapted to task demands during both motor execution and motor planning
用于工业碳捕获和利用的大规模培养海洋硅藻的生物反应器微生物组	Aalto, N. J.	PDF	N/A	The bioreactor microbiome of mass cultivated marine diatoms for industrial carbon capture and utilization
eIF3与高度翻译的mRNA的3'-UTR末端结合	Mestre-Fos, S.	PDF	N/A	eIF3 engages with 3'-UTR termini of highly translated mRNAs
低盐度显著改变了海洋基础物种昆布（Saccharina latissima，糖海带）的细菌群落。	Schenk, S.	PDF	N/A	Low salinity significantly alters the bacterial community of the marine foundation species Saccharina latissima (sugar kelp)
肌动蛋白动力学调控卵黄囊内脏内胚层细胞中两种不同的内体融合模式	Koike, S.	PDF	N/A	Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells
港海豹（Phoca vitulina）的触须空间排列与小鼠（Mus musculus）和大鼠（Rattus norvegicus）的触须排列比较	Graff, M. M.	PDF	N/A	Spatial arrangement of the whiskers of harbor seals (Phoca vitulina) compared to whisker arrangements of mice (Mus musculus) and rats (Rattus norvegicus)
AKAP/AC纳米域上钙-cAMP振荡的时空协调受一个不连贯前馈环路的调控。	Qiao, L.	PDF	N/A	Spatiotemporal orchestration of calcium-cAMP oscillations on AKAP/AC nanodomains is governed by an incoherent feedforward loop
牛磺酸泛基因组揭示了与白头牛脱色素相关的KIT上游的片段重复	Milia, S.	PDF	N/A	Taurine pangenome uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle
在Hydra水螅的头再生过程中，Notch信号传导是介导两个模式形成过程所必需的。	Steichele, M.	PDF	N/A	Notch-signaling is required for mediating between two pattern forming processes during head regeneration in Hydra polyps
从质量加权浓度分布的矩差推断代谢通量	Tuobang, L.	PDF	N/A	Infer metabolic fluxes from moment differences of mass-weighted concentration distributions
在人工耳蜗植入儿童中神经语音跟踪的恢复力和脆弱性	Federici, A.	PDF	N/A	Resilience and vulnerability of neural speech tracking in children with cochlear implants
盐度耐受性的昼夜调节：Vigna marina中SOS途径和钠排泄的昼夜调控机制	Noda, Y.	PDF	N/A	Diurnal regulation of SOS Pathway and Sodium Excretion Underlying Salinity Tolerance of Vigna marina
果蝇中性别特异性行为的昼夜节律控制	Franco, D. L.	PDF	N/A	Circadian control of a sex-specific behaviour in Drosophila
解决二聚体形式的途径将肠杆菌科中的质粒与巨型质粒区分开来。	Fournes, F.	PDF	N/A	The pathway to resolve dimeric forms distinguishes plasmids from megaplasmids in Enterobacteriaceae
用于延时摄像机监测昆虫及其花卉环境的一个深度学习流程	Bjerge, K.	PDF	N/A	A deep learning pipeline for time-lapse camera monitoring of insects and their floral environments
一种血清素类致幻剂的双受体模型	Juliani, A.	PDF	N/A	A dual-receptor model of serotonergic psychedelics
单细胞RNA测序揭示的Wilson病中自然杀伤细胞耗竭预测胆囊炎的预后	Jin, Y.	PDF	N/A	NK Cell Exhaustion in Wilson's Disease Revealed by Single-cell RNA Sequencing Predicts the Prognosis of Cholecystitis
前颞区双向连接性的变化反映了多声部音乐中的图形-背景反转	Kim, C. H.	PDF	N/A	Bidirectional connectivity changes in the frontotemporal areas reflect figure-ground reversal in multivoiced music
用于纵向微生物组研究的微生物网络推断方法——LUPINE	Kodikara, S.	PDF	N/A	Microbial network inference for longitudinal microbiome studies with LUPINE
防御反应中小分泌肽信号的比较分析：来自维管植物和非维管植物的见解	Lyapina, I.	PDF	N/A	Comparative Analysis of Small Secreted Peptide Signaling during Defense Response: Insights from Vascular and Non-Vascular Plants
人类出生组织产品作为非阿片类药物抑制术后疼痛	Zhang, C.	PDF	N/A	Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain
人类皮层下听觉异常检测：一项ABR研究	Wetekam, J.	PDF	N/A	Subcortical Auditory Deviance Detection in Humans: An ABR Study
双组分信号决定哪些锈菌分泌的蛋白质被转运到寄主植物细胞中	Lawrence, G. J.	PDF	N/A	A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant
来自帕金森病患者iPSCs的LRRK2-G2019S突变衍生的少突胶质前体细胞的单细胞转录组变化	Dehestani, M.	PDF	N/A	Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation
一种新出现的PB2-627多态性通过突破哺乳动物和禽类宿主中的ANP32限制，增强了禽流感病毒的大流行潜力。	Guo, Y.	PDF	N/A	An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts
年轻鱼类的肖像：从东格陵兰早三叠纪的幼体标本重新描述Pteronisculus gunnari (Nielsen, 1942)，并探讨其对早期辐鳍鱼类个体发育的影响	Cavicchini, I.	PDF	N/A	A Portrait of a Young Fish: Redescription of Pteronisculus gunnari (Nielsen, 1942) from a juvenile specimen from the Early Triassic of East Greenland, with implications for ontogenetic development in early actinopterygians
质粒病毒维持能够使细菌种群从感染中恢复，并实现病毒与细菌的共存。	Sanchez-Martinez, R.	PDF	N/A	Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence
动物基因组结构的保守性是例外，而非普遍规律。	Lewin, T. D.	PDF	N/A	Conservation of animal genome structure is the exception not the rule
厌氧消化共生体中关键功能种群的代谢隔离与特征基因簇	Wang, Y.	PDF	N/A	Metabolic Segregation and Characteristic Gene clusters of the Key Functional Populations in Anaerobic Digestion Consortia
重新评估社会排斥的神经相关性：一项使用动脉自旋标记技术的网络球范式复制研究	Labek, K.	PDF	N/A	Reassessing the Neural Correlates of Social Exclusion: A Replication Study of the Cyberball Paradigm Using Arterial Spin Labelling
用于日本脑炎和西尼罗病毒的感染性亚基因组扩增子策略	Singh, P. P.	PDF	N/A	Infectious subgenomic amplicon strategies for Japanese encephalitis and West Nile viruses
雄性和雌性小鼠分别与同性和异性同类形成了更强的社会性厌恶记忆。	Beaver, J. N.	PDF	N/A	Male and female mice respectively form stronger social aversive memories with same and different sex conspecifics
纤维素涂料：一类淀粉样蛋白靶向肽	Pedrola, J. A.	PDF	N/A	Fibril Paint: a class of amyloid-targeting peptides
从头设计Ras同工型选择性结合剂	Zhang, J. Z.	PDF	N/A	De novo design of Ras isoform selective binders
重新审视假单胞菌质粒的不相容性群组：对R质粒及其复制子的综合分析	Nishimura, Y.	PDF	N/A	Incompatibility groups of Pseudomonas plasmids revisited: comprehensive analysis of R-factors and their replicons
在患者层面建模意识障碍揭示了网络对诊断的影响与局部节点参数在预后中的作用	Zonca, L.	PDF	N/A	Modeling disorders of consciousness at the patient level reveals the network's influence on the diagnosis vs the local node parameters role in prognosis
基因组变化在同属物种对之间是多样的	Francis, W. R.	PDF	N/A	Genomic changes are varied across congeneric species pairs
脂联素信号在调节小鼠对脂肪味觉的反应中起作用。	Lin, F.	PDF	N/A	Adiponectin signaling modulates fat taste responsiveness in mice
远程缺血预处理通过CD36介导的吞噬作用减轻跨神经元变性并促进中风恢复。	Ju, H.	PDF	N/A	Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis.
威尔姆斯瘤中亚型特异性进化模式及临床相关基因组不稳定性的研究	Cresswell, G. D.	PDF	N/A	Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour
sTREM2的柔性茎域调节其与脑内磷脂的相互作用	Saeb, D.	PDF	N/A	The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain
人类和蝙蝠基因组在COSMIC突变特征下的稳健性	Song, J.-H.	PDF	N/A	Human and bats genome robustness under COSMIC mutational signatures
结核分枝杆菌拓扑异构酶I在C端缺失后能量上受到严重影响	Balthrop, D.	PDF	N/A	Mycobacterial Topoisomerase I Energetically Suffers From C-Terminal Deletions
促性腺激素细胞具有双重起源，其中大多数在微青春期期间源自垂体干细胞。	Sheridan, D.	PDF	N/A	Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty.
胞外囊泡通过将ATP合成转运至伪足并激活整合素粘附复合物，调控淋巴管平滑肌瘤细胞的亚稳态表型。	Kalvala, A. K.	PDF	N/A	Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes.
SAF-A SAP结构域在X染色体失活、转录、剪接和细胞增殖中的作用	Sharp, J. A.	PDF	N/A	Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation
三种自闭症谱系障碍亚型及其转录组特征：基于形态学相似性网络的推导	Jiang, H.	PDF	N/A	Three Subtypes Of Autism Spectrum Disorder With Transcriptomic Signatures Derived From Morphometric Similarity Networks
胚胎增强子元件的表观遗传启动协调发育基因网络	Todd, C. D.	PDF	N/A	Epigenetic priming of embryonic enhancer elements coordinates developmental gene networks
腹侧被盖区多巴胺神经活动与前额叶皮层和海马体中的规则表征同时切换	Ding, M.	PDF	N/A	Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus
行为状态和刺激强度调节生长抑素中间神经元在稳定网络活动中的作用	Cammarata, C. M.	PDF	N/A	Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity
早期生活压力影响小鼠的癫痫结果	Coleman, E. M.	PDF	N/A	Early life stress influences epilepsy outcomes in mice
早期精神病患者灰质和白质中的神经突密度和自由水	Van Dyken, P. C.	PDF	N/A	Neurite Density and Free Water in the Gray and White Matter of Early Psychosis Patients
人类小脑中浦肯野细胞树突的非等比扩展及增强的区室化	Busch, S. E.	PDF	N/A	Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum
具身视角：角回和楔前叶在自然事件记忆中解码自我	Iriye, H.	PDF	N/A	An embodied perspective: angular gyrus and precuneus decode selfhood in memories of naturalistic events
在发育中的新皮质中，Rbfox1/2/3对转录调节因子和Ptbp1的细胞类型特异性剪接	Ruan, X.	PDF	N/A	Cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex
在过去500万年间，气候环境对人类脑容量的影响	Nicholson, S. L.	PDF	N/A	Climatic-environmental influences on hominin brain size over the last 5 million years
THz电磁场对离子通道影响的模拟协议	Xue, L.	PDF	N/A	Protocol for Simulating the Effect of THz Electromagnetic Field on Ion Channels
自闭症谱系障碍的Shank3-/-小鼠模型中前额叶回路功能障碍的发展进程	Devienne, G.	PDF	N/A	Developmental progression of prefrontal circuit dysfunction in a Shank3-/- mouse model of autism spectrum disorder
TMPRSS6 切割 KCNE1 并在铁超载疾病中引发心律失常	Peischard, S.	PDF	N/A	TMPRSS6 cleaves KCNE1 and causes arrhythmias in iron overload disease
生酮干预措施能恢复认知功能并调节阿尔茨海默病小鼠模型中的外周代谢紊乱。	M'Bra, P. E. H.	PDF	N/A	Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models
肥大细胞促进结核病病理和易感性	Gupta, A.	PDF	N/A	Mast cells promote pathology and susceptibility in tuberculosis
HIV-1包膜可变区1中罕见的双半胱氨酸残基与中和逃逸及广谱性发展相关联	Hesselman, M. C.	PDF	N/A	Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development
解析TLR4和性别对慢性酒精摄入引起的细胞外囊泡脂质组失调的影响	Perpina-Clerigues, C.	PDF	N/A	Unravelling the impact of TLR4 and sex on chronic alcohol consumption-induced lipidome dysregulation in extracellular vesicles
Rad18在维持胶质母细胞瘤增殖中的一种非催化功能	Benbahouche, N. E.-H.	PDF	N/A	A non-catalytic function for Rad18 in sustaining glioblastoma proliferation
近乎完整的鬃狮蜥（Pogona vitticeps）基因组组装为揭示鬃狮蜥性染色体的起源提供了洞见。	Guo, Q.	PDF	N/A	A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes
天堂鱼（Macropodus opercularis）作为情感和认知功能的新型转化模型	Varga, Z. K.	PDF	N/A	Paradise fish (Macropodus opercularis) as novel translational model for emotional and cognitive function
通过贝叶斯优化和深度学习实现复杂癌细胞球的高分辨率单细胞分割	Mogollon, I.	PDF	N/A	Achieving high-resolution single-cell segmentation in convoluted cancer spheroids via Bayesian optimization and deep-learning
胶质瘤中CD200的耗竭增强了抗肿瘤免疫并诱导了肿瘤排斥	Raphael, I.	PDF	N/A	CD200 depletion in glioma enhances antitumor immunity and induces tumor rejection
跨环境与依赖情境的互侵入性下，从菌株频率数据中推断成对相互作用的嵌套推断	Le, T. M. T.	PDF	N/A	Nested inference of pairwise interactions from strain frequency data across settings and context-dependent mutual invasibilities
美国东南部两种蚂蚁的行为互动及本地超级蚁群的证据	Kanwar, S.	PDF	N/A	Behavioral Interactions in Two Ant Species in The Southeast United States and Evidence for a Native Supercolony
胆固醇在M2簇集和病毒出芽中的作用解析	Kolokouris, D.	PDF	N/A	The Role of Cholesterol in M2 Clustering and Viral Budding Explained
FGFR2促进对ALK酪氨酸激酶抑制剂的耐药性，其抑制作用与lorlatinib联合使用在治疗表达ALK的神经母细胞瘤中具有协同效应。	Pucci, P.	PDF	N/A	FGFR2 promotes resistance to ALK tyrosine kinase inhibitors and its inhibition acts synergistically with lorlatinib in the treatment of ALK-expressing neuroblastoma
分布式学习驱动统计性聋化	Luthra, S.	PDF	N/A	Distributional learning drives statistical deafening
解决功能性神经成像中的不一致性：一种可复现的数据驱动多尺度功能图谱，用于典型脑网络	Jensen, K. M.	PDF	N/A	Addressing inconsistency in functional neuroimaging: A replicable data-driven multi-scale functional atlas for canonical brain networks
弓形虫细胞周期检查点激酶的特征分析	Johnson, M. K.	PDF	N/A	Characterisation of cell cycle checkpoint kinases in Toxoplasma gondii
一些人工智能工具在针对猫传染性腹膜炎病毒（FIPV）主要病毒蛋白酶的某些化合物药物设计中的应用	Khan, M. Y.	PDF	N/A	Applications of some artificial intelligence tools in the drug design of some compounds targeting the main viral protease of the Feline Infectious Peritonitis Virus (FIPV) in cats
蝾螈表观遗传时钟提供了对可忽略衰老本质的见解。	Haluza, Y.	PDF	N/A	Axolotl epigenetic clocks offer insights into the nature of negligible senescence
染色质重塑因子DEK促进乳腺上皮细胞的增殖，并与H3K27me3表观遗传修饰相关。	Johnstone, M.	PDF	N/A	The chromatin remodeler DEK promotes proliferation of mammary epithelium and is associated with H3K27me3 epigenetic modifications
无意义错误的重要性：估计蛋白质合成过程中脱落错误的速率及其影响	Cope, A. L.	PDF	N/A	The Importance of Nonsense Errors: Estimating the Rate and Implications of Drop-Off Errors during Protein Synthesis
海洋捕食性蜗牛毒液生产的演化	Zancolli, G.	PDF	N/A	Evolution of venom production in marine predatory snails
FishPi：一种生物信息学预测工具，用于在斑马鱼中关联piRNA和转座元件	Godden, A. M.	PDF	N/A	FishPi: a bioinformatic prediction tool to link piRNA and transposable elements in zebrafish
黑水虻的控制性多配交配：通过数量遗传设计推进育种计划	Jensen, K.	PDF	N/A	Controlled and polygynous mating in the black soldier fly: advancing breeding programs through quantitative genetic designs
RNA聚合酶II和III招募到snRNA启动子的不同机制的结构见解	Shah, S. Z.	PDF	N/A	Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters
scDrugAtlas：一个综合性的单细胞药物反应图谱，用于揭示治疗效果中的肿瘤异质性	Huang, W.	PDF	N/A	scDrugAtlas: an integrative single-cell drug response atlas for unraveling tumor heterogeneity in therapeutic efficacy
皮肤成纤维细胞异质性的共识单细胞转录组图谱	Ascension, A. M.	PDF	N/A	A consensus single-cell transcriptomic atlas of dermal fibroblast heterogeneity
使用Exeter Multiscope自动测量心肌细胞单层收缩	Corbett, A. D.	PDF	N/A	Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope
LYMTACs：嵌合小分子重新利用溶酶体膜蛋白实现目标蛋白的重新定位与降解	Nalawansha, D. A.	PDF	N/A	LYMTACs: Chimeric Small Molecules Repurpose Lysosomal Membrane Proteins for Target Protein Relocalization and Degradation
两种非小细胞肺癌亚型之间转录组和蛋白质组表达的比较分析	Nicholas, B.	PDF	N/A	Comparative analysis of transcriptomic and proteomic expression between two non-small cell lung cancer subtypes
赖氨酰氧化酶对小鼠子宫肌层收缩力和及时分娩是必要的	Ouellette, A.	PDF	N/A	Lysyl Oxidases are Necessary for Myometrial Contractility and On-Time Parturition in Mice
左心房应变作为压力超负荷小鼠模型中心脏功能障碍的预测因子	Salvas, J. P.	PDF	N/A	Left Atrial Strain as a Predictor of Cardiac Dysfunction in a Murine Model of Pressure Overload
ERC1的生物分子凝聚招募ATG8和NBR1，驱动自噬小体的形成，以促进植物的热耐受性。	Chung, K. K.	PDF	N/A	Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance
尽管四维流磁共振成像（4D flow MRI）中存在非正态误差，心血管数字孪生中的不确定性：识别可靠的生物标志物，如心室舒张率	Tunedal, K.	PDF	N/A	Uncertainty in cardiovascular digital twins despite non-normal errors in 4D flow MRI: identifying reliable biomarkers such as ventricular relaxation rate
通过电影驱动的超高场fMRI识别人类和小猕猴大脑网络中的功能同源体	Zanini, A.	PDF	N/A	Identifying Functional Homologues in Human and Marmoset Brain Networks via Movie-Driven Ultra-High Field fMRI
啮齿动物连续表现测试中与任务时间相关的性能下降并非由任务中的身体脱离引起。	Li, Y.	PDF	N/A	Time-on-task-related decrements in performance in the rodent continuous performance test are not caused by physical disengagement from the task
评估用于人类脊髓非侵入性电生理学的噪声校正方法	Bailey, E.	PDF	N/A	Evaluating noise correction approaches for non-invasive electrophysiology of the human spinal cord
任务时间越长，注视漂移增加	Friedman, L.	PDF	N/A	Fixation Drift Increases as a Function of Time-on-Task
新近习得的词语-动作关联在运动准备期间触发听觉皮层激活：对动作词语学习中的赫布可塑性的启示	Tretyakova, V.	PDF	N/A	Newly Acquired Word-Action Associations Trigger Auditory Cortex Activation During Movement Preparation: Implications for Hebbian Plasticity in Action Words Learning
单侧手部肌肉收缩对内在奖励情境下额叶alpha不对称性和抑制控制的影响：一项随机对照试验	Akil, A. M.	PDF	N/A	The effect of unilateral hand muscle contraction on frontal alpha asymmetry and inhibitory control in intrinsic reward contexts, a randomized controlled trial
从视觉皮层活动的动态估计注意力场	Bloem, I. M.	PDF	N/A	Dynamic estimation of the attentional field from visual cortical activity
跨突触IgLON黏附分子复合物直接接触并聚集烟碱型受体	Mialon, M.	PDF	N/A	A trans-synaptic IgLON adhesion molecular complex directly contacts and clusters a nicotinic receptor
β2-肾上腺素能偏向激动剂以NF-κB依赖的方式抑制Th17的发育及记忆Th17细胞的反应。	Hajiaghayi, M.	PDF	N/A	β2-Adrenergic Biased Agonist Inhibits the Development of Th17 and the Response of Memory Th17 Cells in an NF-κB-Dependent Manner.
免疫细胞对弥漫性大B细胞淋巴瘤的影响：孟德尔随机化分析	He, H.	PDF	N/A	Immune Cell Influence on Diffuse Large B-Cell Lymphoma: A Mendelian Randomization Analysis
通过数字空间分析确定的原发性子宫癌肉瘤中肿瘤间和肿瘤内异质性免疫表现	Li, Y.	PDF	N/A	Inter- and intra-tumor heterogeneous immune presentation in primary uterine carcinosarcoma determined by digital spatial profiling
基因编码的FerriTag作为冷冻电子断层扫描的特异性标记	Wang, C.	PDF	N/A	Genetically Encoded FerriTag as a Specific Label for Cryo-Electron Tomography
两个世纪以来环境变化中植物-真菌共生现象的日益普遍	Fowler, J. C.	PDF	N/A	Increasing prevalence of plant-fungal symbiosis across two centuries of environmental change
生殖干扰能否融入害虫控制的绝育昆虫技术？来自斑翅果蝇Drosophila suzukii的启示	Cerasti, F.	PDF	N/A	Can reproductive interference be integrated into the Sterile Insect Technique for pest control? Insights from the spotted wing fly Drosophila suzukii
印度鸟类状况2023：利用半结构化公民科学促进鸟类保护的框架	Viswanathan, A.	PDF	N/A	State of India's Birds 2023: A framework to leverage semi-structured citizen science for bird conservation
小鼠属中不同CD8+ α/β-TCR库的遗传决定因素	Peters, M. A.	PDF	N/A	Genetic determinants of distinct CD8+ α/β-TCR repertoires in the genus Mus
个人空间与群体灾难中的集体行为	Lugo, I.	PDF	N/A	The personal space and the collective behavior of crowd disasters
通过分布匹配实现结构脑连接的协调	Zhou, Z.	PDF	N/A	Harmonization of Structural Brain Connectivity through Distribution Matching
靶向聚合物囊泡可增强损伤后外周神经的递送	Trumbull, K.	PDF	N/A	Targeted Polymersomes Enable Enhanced Delivery to Peripheral Nerves Post-Injury
一种新型的小鼠前肢生物力学模型在最佳控制模拟的抓取运动中预测肌肉活动	Gilmer, J. I.	PDF	N/A	A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements
揭示基于芯片的周围神经系统和中枢神经系统中神经元靶向树枝状聚合物在siRNA递送中的潜力	Spencer, A. P.	PDF	N/A	Unveiling the potential of neuron-targeted dendriplexes for siRNA delivery using a PNS-CNS-on-Chip
工程化壳聚糖衍生纳米载体用于高效外周和中枢神经元siRNA递送	Spencer, A. P.	PDF	N/A	Engineered chitosan-derived nanocarrier for efficient siRNA delivery to peripheral and central neurons
利用蛋白质生物信息学深入挖掘免疫肽组学数据集	Boughter, C. T.	PDF	N/A	Utilizing Protein Bioinformatics to Delve Deeper Into Immunopeptidomic Datasets
LLPS REDIFINE 能够对多组分凝聚物进行生物物理特性表征，无需任何标签或标记。	Novakovic, M.	PDF	N/A	LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels
恒温动物体温的分子起源	Artmann, G. M.	PDF	N/A	The molecular origin of body temperature in homeothermic species
阐明电压门控钠通道中等效门控电荷突变的差异性影响	Elhanafy, E.	PDF	N/A	Elucidating the Differential Impacts of Equivalent Gating-Charge Mutations in Voltage-Gated Sodium Channels
致癌驱动突变N642H在STAT5B SH2结构域中的结构影响	Haas-Neill, L.	PDF	N/A	The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain
细胞内核磁共振显示，细胞会选择性地放大和结构重塑淀粉样纤维。	Ansari, S.	PDF	N/A	In cell NMR reveals cells selectively amplify and structurally remodel amyloid fibrils
探索从热力学稳定和动力学陷阱的枯草杆菌蛋白酶ISP1和SbtE的能量景观的序列和结构决定因素	Hood, M. R.	PDF	N/A	Exploring the sequence and structural determinants of the energy landscape from thermodynamically stable and kinetically trapped subtilisins: ISP1 and SbtE
多稳态、吸收边界和生长对图灵模式形成的影响	Oliver Huidobro, M.	PDF	N/A	Effects of multistability, absorbing boundaries and growth on Turing pattern formation
在生长诱导压力下，细胞干质量密度增加。	Kim, H.	PDF	N/A	Intracellular dry mass density increases under growth-induced pressure
在PET降解酶的共振分配中，操作温度下的核磁共振（NMR）	Gabrielli, V.	PDF	N/A	NMR at operational temperature for resonance assignments of a PET degrading enzyme
Zellweger谱系障碍的PEX1-p.Gly844Asp小鼠模型中视网膜色素上皮结构和脂质变化的地理特征。	Omri, S.	PDF	N/A	Geographic characterization of RPE structure and lipid changes in the PEX1-p.Gly844Asp mouse model for Zellweger spectrum disorder.
发现新型1,4-二羰基硫代半缩氨基脲作为DNA促旋酶抑制剂用于治疗耐甲氧西林金黄色葡萄球菌感染	Zhang, G.	PDF	N/A	Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection
个体行为表型的漂移作为应对不可预测世界的策略	Maloney, R. T.	PDF	N/A	Drift in Individual Behavioral Phenotype as a Strategy for Unpredictable Worlds
在快速眼动睡眠期间，结构化和非结构化的再激活受到新奇体验的调节。	Choi, J.	PDF	N/A	Structured and unstructured reactivations during REM sleep are modulated by novel experiences
经过训练的腹侧视觉通路深度神经网络模型能够稳健地编码数量信息，而不受物体和场景身份的影响。	Chapalain, T.	PDF	N/A	Trained deep neural network models of the ventral visual pathway encode numerosity with robustness to object and scene identity
小鼠海马中与年龄相关的转录组和表观遗传变化	Bilgic, M.	PDF	N/A	Age-associated transcriptomic and epigenetic alterations in mouse hippocampus
高血糖选择性地增加大脑的非氧化葡萄糖消耗，而不影响血流。	Blazey, T.	PDF	N/A	Hyperglycemia selectively increases cerebral non-oxidative glucose consumption without affecting blood flow
利用扩散磁共振成像绘制人类未定带的地形组织图	Haast, R. A.	PDF	N/A	Mapping the topographic organization of the human zona incerta using diffusion MRI
放射免疫疗法的差异性反应是由肿瘤微环境的内在特征所决定的。	Karam, S. D.	PDF	N/A	Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment
硫酸化糖胺聚糖P3R99单克隆抗体的表征及其抗动脉粥样硬化潜力：物理化学和功能性见解	Valencia, L. M.	PDF	N/A	Characterization and Antiatherogenic Potential of P3R99 Monoclonal Antibody Against Sulfated Glycosaminoglycans: Physicochemical and Functional Insights
活性EB1激增促进双体嗅觉纤毛生长外段中的微管流入	Agarwal, R. G.	PDF	N/A	Active EB1 surges promote tubulin influx into the growing outer segments of the bipartite olfactory cilia in Drosophila
支链氨基酸代谢是细胞衰老的重要调节因子。	Aramaki, Y.	PDF	N/A	Branched-chain amino acid metabolism is a crucial modulator of cellular senescence
鉴定新型肌因子及潜在蛋白质靶点，这些因子介导了长期收缩活动诱导的骨骼肌-细胞外囊泡处理后的功能适应	Obi, P. O.	PDF	N/A	Identification of novel myokines and putative protein targets that mediate functional adaptations in response to chronic contractile activity induced skeletal muscle-extracellular vesicle treatment
一个流体液滴收集了活细胞中微管收缩所产生的力	Morelli, K.	PDF	N/A	A fluid droplet harvests the force generated by shrinking microtubules in living cells
在数据旅程中学到的教训：从实验到预测激酶亲和力、选择性、多靶点药理学和耐药性的模型	Lopez-Rios de Castro, R.	PDF	N/A	Lessons learned during the journey of data: from experiment to model for predicting kinase affinity, selectivity, polypharmacology, and resistance
雌性大鼠中存在明显的操作性行为表型及短暂戒断引发的酒精摄入量增加现象	Pitock, J. R.	PDF	N/A	Presence of distinct operant phenotypes and transient withdrawal-induced escalation of operant ethanol intake in female rats
胶质细胞会多任务处理以弥补邻近胶质细胞的功能障碍。	Beachum, A. N.	PDF	N/A	Glia multitask to compensate for neighboring glial cell dysfunction
将植物来源的化合物芹菜素重新用于抗衰老流程中的衰老效应	Zhang, H.	PDF	N/A	Repurposing the plant-derived compound apigenin for senomorphic effect in antiaging pipelines
推算的DNA甲基化在吸烟和生理年龄的关联性上优于测量的位点	Richmond, A.	PDF	N/A	Imputed DNA methylation outperforms measured loci associations with smoking and chronological age
工程化生长素诱导的降解子系统以实现对生物体生理的可调节体内控制	Vicencio, J.	PDF	N/A	Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology
健康小鼠中的司美格鲁肽给药改变了与压力和动机相关的行为	Moreno, A.	PDF	N/A	Semaglutide Administration in Healthy Mice Alters Behaviour Related to Stress and Motivation
CD300f免疫受体是一种小胶质细胞组织损伤传感器，并在脑损伤后调节吞噬作用。	Negro-Demontel, M. L.	PDF	N/A	CD300f immune receptor is a microglial tissue damage sensor and regulates efferocytosis after brain damage
自身抗原TRIM21（Ro52）在溶细胞死亡后组装促炎性免疫复合物	Jones, E. L.	PDF	N/A	Autoantigen TRIM21 (Ro52) assembles pro-inflammatory immune complexes following lytic cell death
利用知识图谱理解生态系统：以高致病性禽流感为例的应用	Robertson, H.	PDF	N/A	Understanding Ecological Systems Using Knowledge Graphs: An Application to Highly Pathogenic Avian Influenza
无血清食品级和复杂培养基生产对培养肉的环境影响	Takenaka, N.	PDF	N/A	Environmental Impacts of Serum-free Food-grade and Complex Culture Medium Production for Cultivated Meat
海洋储库中生物碳的滞留时间和遗留效应	Visser, A. W.	PDF	N/A	Residence Times and Legacy of Biogenic Carbon in Ocean Reservoirs
用于乙二醇同化的合成代谢途径优于天然途径	Feigis, M.	PDF	N/A	Synthetic metabolic pathways for ethylene glycol assimilation outperform natural counterparts
测量人体胸主动脉及主动脉夹层模型中由磁共振弹性成像导出的硬度的可行性研究	Hirad, A. A.	PDF	N/A	Feasibility of Measuring Magnetic Resonance Elastography-derived Stiffness in Human Thoracic Aorta and Aortic Dissection Phantoms
高眼压对筛板氧合的影响：一项关于猴子的实验-计算联合研究	Lu, Y.	PDF	N/A	Impact of elevated IOP on lamina cribrosa oxygenation; A combined experimental-computational study on monkeys
比较软组织的连续体模型和直接纤维模型。一个眼生物力学的例子揭示了连续体模型可能会在组织和纤维层面人为地破坏应变。	He, X.	PDF	N/A	Comparing continuum and direct fiber models of soft tissues.An ocular biomechanics example reveals that continuum models may artificially disrupt the strains at both the tissue and fiber levels
FAIR数据点填充器：协作的FAIR化与FAIR数据点的填充	Wijnbergen, D.	PDF	N/A	The FAIR Data Point Populator: collaborative FAIRification and population of FAIR Data Points
基于云的大规模蛋白质组学队列可扩展分析	Guturu, H.	PDF	N/A	Cloud-enabled Scalable Analysis of Large Proteomics Cohorts
脂肪细胞前体是乳腺腺体突然退化后维持的受损上皮微环境的主要贡献者。	Joshi, P. A.	PDF	N/A	Adipocyte progenitors are primary contributors to the disrupted epithelial niche that is sustained following abrupt mammary gland involution
在表达α-平滑肌肌动蛋白的细胞中敲除LRP6，能阻断博莱霉素诱导的肺损伤后的肺部炎症和纤维化。	Sung, E.-A.	PDF	N/A	Ablation of LRP6 in alpha-smooth muscle actin-expressing cells abrogates lung inflammation and fibrosis upon bleomycin-induced lung injury
脂肪细胞特异性缺失Dbc1并不能重现健康肥胖表型，但提示其对炎症信号的调控作用	Santos, L.	PDF	N/A	Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling
一种生理学启发的混合CPG/反射控制器，适用于自行车模拟，并能推广到步行	Severini, G.	PDF	N/A	A physiologically inspired hybrid CPG/Reflex controller for cycling simulations that generalizes to walking
在激活周围神经方面，时间干扰刺激与直接千赫兹刺激之间不存在生物物理学上的区别。	Opancar, A.	PDF	N/A	There is no Biophysical Distinction between Temporal Interference Stimulation and Direct kHz Stimulation for Actuation of Peripheral Nerves
DendroTweaks：一种揭示树突动力学的交互式方法	Makarov, R.	PDF	N/A	DendroTweaks: An interactive approach for unraveling dendritic dynamics
利用空间转录组学技术揭示人类阿尔茨海默病大脑中的斑块-胶质细胞生态位	Avey, D. R.	PDF	N/A	Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics
心肌肌球蛋白复合物的神经符号混合模型从其遗传编码中解码可遗传心脏病的结构基础	Burghardt, T. P.	PDF	N/A	Neural-symbolic hybrid model for myosin complex in cardiac ventriculum decodes structural bases for inheritable heart disease from its genetic encoding
一种用于高度稀疏、高维、成分数据集的半参数多重插补方法	Sohn, M. B.	PDF	N/A	A semi-parametric multiple imputation method for high-sparse, high-dimensional, compositional data
用于fNIRS脑状态分类的黎曼几何	Näher, T.	PDF	N/A	Riemannian Geometry for the Classification of Brain States with fNIRS
利用4D Flow MRI-CFD联合框架研究主动脉瓣狭窄引起的心血管血流模式	Wang, T.	PDF	N/A	Investigation of hemodynamic bulk flow patterns caused by aortic stenosis using a combined 4D Flow MRI-CFD framework
视网膜筛板和胶质层中星形胶质细胞的形态学比较	Waxman, S.	PDF	N/A	Morphological comparison of astrocytes in the lamina cribrosa and glial lamina
用于电刺激大脑的喷墨打印透明电极	Matta, R.	PDF	N/A	Inkjet-printed transparent electrodes for electrical brain stimulation
SARS-CoV-2主蛋白酶活性位点环的构象空间由配体结合和蛋白质间别构效应决定。	Lee, E.	PDF	N/A	The Conformational Space of the SARS-CoV-2 Main Protease Active Site Loops is Determined by Ligand Binding and Interprotomer Allostery
果蝇母体向合子过渡期间先锋因子结合动力学的批量级图谱	Dima, S. S.	PDF	N/A	Bulk-level maps of pioneer factor binding dynamics during Drosophila maternal-to-zygotic transition
莱姆病螺旋体的跨内皮迁移涉及通过涉及Cdc42和Rac1的跨细胞途径作为中间步骤的螺旋体内化过程。	Alvarez-Olmedo, D.	PDF	N/A	Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1
全生物体的外部微生物组调节了内部共生体的适应性。	Imchen, M.	PDF	N/A	The holobiont's extracellular microbiome modulates the adaptation of an intracellular endosymbiont
在铜绿假单胞菌中，体内暴露于头孢他啶/阿维巴坦后导致对头孢洛扎/他唑巴坦和亚胺培南/西司他丁/瑞来巴坦耐药的突变	Rapsinski, G. J.	PDF	N/A	Mutations Leading to Ceftolozane/Tazobactam and Imipenem/Cilastatin/Relebactam Resistance During in vivo exposure to Ceftazidime/Avibactam in Pseudomonas aeruginosa
生物膜粘附蛋白的缺失改变了Desulfovibrio vulgaris Hildenborough的表面附着和细胞策略	Pickens, C. P.	PDF	N/A	Absence of biofilm adhesin proteins changes surface attachment and cell strategy for Desulfovibrio vulgaris Hildenborough
生物多样性热点地区的小型哺乳动物携带具有流行潜力的病毒	Feng, Y.	PDF	N/A	Small mammals in biodiversity hotspot harbor viruses of epidemic potential
流感病毒A型高效基因组复制需要NS2及规范启动子序列之外的序列	Swaminath, S.	PDF	N/A	Efficient genome replication in influenza A virus requires NS2 and sequence beyond the canonical promoter
一个稳定的15成员细菌SynCom在干旱胁迫下促进短柄草的生长	Yadav, A.	PDF	N/A	A stable 15-member bacterial SynCom promotes Brachypodium growth under drought stress
转录因子Traffic jam在果蝇卵巢中调控体细胞piRNA通路	Brasset, E.	PDF	N/A	The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries
依赖ATP的染色质凝聚物重塑揭示了两种重塑因子不同的中尺度效应	Moore, C. M.	PDF	N/A	ATP-dependent remodeling of chromatin condensates uncovers distinct mesoscale effects of two remodelers
肌动蛋白纤维切割和封端的机制：Gelsolin的作用	Barrie, K. R.	PDF	N/A	Mechanism of Actin Filament Severing and Capping by Gelsolin
一种用于研究染色质中组蛋白H3的圆形工程化sortase	Whedon, S. D.	PDF	N/A	A circular engineered sortase for interrogating histone H3 in chromatin
高度迭代回文序列1（HIP1）通过同源依赖和甲基化依赖的方式提高了聚球藻PCC 7002的转化效率	Kamoku, C.	PDF	N/A	Highly Iterated Palindrome 1 (HIP1) sequence improves Synechococcus sp. PCC 7002 transformation efficiencies in a homology- and methylation-dependent manner
非洲猪瘟病毒基因MGF_360-4L通过招募线粒体选择性自噬受体SQSTM1降解MDA5，从而抑制干扰素信号传导，对抗先天免疫反应。	Niu, Q.	PDF	N/A	The African Swine Fever Virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses
两组分系统ArlRS对金黄色葡萄球菌中壁磷壁酸的糖基开关切换至关重要。	Kuijk, M. M.	PDF	N/A	The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus
维多利亚州考拉中重组考拉逆转录病毒（recKoRV）的高频检测表明KoRV的历史整合	Legione, A. R.	PDF	N/A	A High Frequency of Detection of Recombinant Koala Retrovirus (recKoRV) in Victorian Koalas Suggests Historic Integration of KoRV
表皮生长因子受体信号调控宿主对侵袭性曲霉病的炎症反应	Liu, H.	PDF	N/A	Epidermal Growth Factor Receptor Signaling Governs the Host Inflammatory Response to Invasive Aspergillosis
开发了一种竞争性检测方法，用于评估登革病毒血清型在体外适应性，采用优化的血清型特异性qRT-PCR技术。	Griffon, A.-F.	PDF	N/A	Development of a competition assay to assess the in vitro fitness of dengue virus serotypes using an optimized serotype-specific qRT-PCR
探索褐球藻界：描述南大洋沿岸及实验室培养的南极褐球藻群落微生物群	Brisbin, M. M.	PDF	N/A	Exploring the Phaeosphere: characterizing the microbiomes of Phaeocystis antarctica colonies from the coastal Southern Ocean and laboratory culture
体内CRISPR筛选鉴定出GRA12作为跨越弓形虫株系和鼠亚种的超越性分泌致病因子	Torelli, F.	PDF	N/A	In vivo CRISPR screens identify GRA12 as a transcendent secreted virulence factor across Toxoplasma gondii strains and mouse subspecies
抗病毒机制及金刚烷胺类似物对基于M2 S31N药物抗性流感A病毒的持续抑制作用的临床前评估	Tietjen, I.	PDF	N/A	Antiviral Mechanisms and Preclinical Evaluation of Amantadine Analogs that Continue to Inhibit Influenza A Viruses with M2 S31N-Based Drug Resistance
非模式福赛斯坦纳菌基因缺失条件质粒的开发	zhou, p.	PDF	N/A	Development of a Conditional Plasmid for Gene Deletion in Non-Model Fusobacterium nucleatum strains
人类CCR4-NOT是一个基因表达的全局调控因子，并且是一种新型逆转录转座子激活的沉默因子。	Kulkarni, S.	PDF	N/A	Human CCR4-NOT is a global regulator of gene expression and is a novel silencer of retrotransposon activation
EPOP通过直接调节酶复合物二聚化，限制PRC2.1对染色质的靶向作用。	Gong, L.	PDF	N/A	EPOP Restricts PRC2.1 Targeting to Chromatin by Directly Modulating Enzyme Complex Dimerization
ALX4二聚体的结构和生化特性分析揭示了疾病等位基因如何影响ALX4功能的新见解	Cain, B.	PDF	N/A	Structural and biochemical characterization of the ALX4 dimer reveals novel insights into how disease alleles impact ALX4 function
人T细胞白血病病毒的衣壳蛋白是一种潜在的药物靶点。	Yu, R.	PDF	N/A	The Human T-cell Leukemia Virus capsid protein is a potential drug target
《小鼠AAV趋向性综合图谱》	Walkey, C. J.	PDF	N/A	A Comprehensive Atlas of AAV Tropism in the Mouse
平滑肌Cxcl12激活与流体诱导的肺动脉高压中的血管重塑相关	Klouda, T.	PDF	N/A	Smooth muscle Cxcl12 activation is associated with vascular remodeling in flow-induced pulmonary hypertension
真核起始因子eIF4F和eIF4B在闭环形成时促进翻译终止	Shuvalova, E.	PDF	N/A	Eukaryotic initiation factors eIF4F and eIF4B promote translation termination upon closed-loop formation
一种雄性精液蛋白SFP-1调控秀丽隐杆线虫雌雄同体交配后的寿命和脂肪代谢	Chen, M.	PDF	N/A	A male seminal fluid protein SFP-1 regulates hermaphrodite post-mating longevity and fat metabolism in Caenorhabditis elegans
高北极地区主要由未被充分描述、基因高度多样的噬菌体所主导。	Lemieux, A.	PDF	N/A	The High Arctic is dominated by uncharacterized, genetically highly diverse bacteriophages
Andexanet alfa在心脏手术中与肝素抵抗的关联：机制与体外视角	Chabata, C. V.	PDF	N/A	Andexanet alfa-associated heparin resistance in cardiac surgery: mechanism and in vitro perspectives
映射非特异性过氧化氢酶的选择性氧化	Homann, D.	PDF	N/A	Mapping Selective Oxidations of Unspecific Peroxygenases
古DNA阐明了属Ctenomys的模式标本的身份和地理起源	Maestri, R.	PDF	N/A	Ancient DNA Clarifies the Identity and Geographic Origin of the holotype of the genus Ctenomys
星形胶质细胞埃兹蛋白定义了小鼠对压力诱导的抑郁行为的恢复力	Lin, S.-S.	PDF	N/A	Astrocyte ezrin defines resilience to stress-induced depressive behaviours in mice
食物-肠道轴：新鲜蔬菜叶际病毒群多样且丰富，并能传递至人类肠道病毒群。	Park, J.-W.	PDF	N/A	The food-gut axis: the phyllosphere virome of fresh vegetables is diverse, abundant, and transmitted to the human gut virome
人类动脉血管的细胞和转录组图谱	Zhao, Q.	PDF	N/A	A cell and transcriptome atlas of the human arterial vasculature
Ki67通过调控染色体周边的核脂质积累，促进有丝分裂期间染色体的个体化。	Hu, H.-T.	PDF	N/A	Ki67 regulates nuclear lipid accumulation at the chromosomal periphery to facilitate chromosome individualization during mitosis
缺氧和GCM1表达的丧失阻止了人类滋养层干细胞的分化及接触抑制	Cinkornpumin, J. K.	PDF	N/A	Hypoxia and loss of GCM1 expression prevents differentiation and contact inhibition in human trophoblast stem cells
Robinow综合征DVL1突变在果蝇疾病模型中破坏形态发生和附肢形成	Akarsu, G.	PDF	N/A	Robinow Syndrome DVL1 mutations disrupt morphogenesis and appendage formation in a Drosophila disease model
神经内分泌通过果蝇血管微环境调控肠道再生	Medina, A.	PDF	N/A	Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila.
急性饮食中蛋氨酸的限制突显了新皮质发育对代谢变化的敏感性。	Saha, S.	PDF	N/A	Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations
一罐蠕虫：估算全球蚯蚓物种数量	Decaens, T.	PDF	N/A	A can of worms: estimating the global number of earthworm species
开发树皮甲虫鉴定工具的进展	Marais, G. C.	PDF	N/A	Progress in Developing a Bark Beetle Identification Tool
草食动物的普遍性在多样化的种植系统中并不能很好地预测产量。	Croijmans, L.	PDF	N/A	Herbivore prevalence poorly predicts yield in diverse cropping systems
格陵兰睡鲨（Somniosus microcephalus）的基因组为极端长寿现象提供了新的见解。	Sahm, A.	PDF	N/A	The Greenland shark (Somniosus microcephalus) genome provides insights into extremelongevity
xCell 2.0：用于细胞类型比例估计的稳健算法，预测免疫检查点阻断反应	Angel, A.	PDF	N/A	xCell 2.0: Robust Algorithm for cell type Proportion Estimation Predicts Response to Immune Checkpoint Blockade
AlphaFold2 筛选自噬中LC3-LIR相互作用的短线性基序（SLiM）	Stuke, J. F. M.	PDF	N/A	AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy
通过三维神经胶质重编程生成人类小清蛋白中间神经元	Stamouli, C. A.	PDF	N/A	Generating human parvalbumin interneurons through 3D glia reprogramming
系统注射东莨菪碱增加了固定头部小鼠的时间预测变异性。	Ujihara, Y.	PDF	N/A	Systemic injection of scopolamine increased the variability of temporal prediction in head-fixed mice.
单细胞基因组和表观基因组共分析揭示了乳腺癌中的硬连线与可塑性	Wang, K.	PDF	N/A	Single cell genome and epigenome co-profiling reveals hardwiring and plasticity in breast cancer
# BioRxiv 2024-09-09 Papers

标题	作者	PDF链接	代码仓库	Title
一种基于反义寡核苷酸的策略，用于改善22q11.2缺失综合征中的认知功能障碍	Thakur, P.	PDF	N/A	An antisense oligonucleotide-based strategy to ameliorate cognitive dysfunction in the 22q11.2 Deletion Syndrome
基于基因组距离的微生物群体结构快速揭示方法（GRUMPS）：一种无需参考的基因组数据清洗方法	Abram, K. Z.	PDF	N/A	Genomic Distance-based Rapid Uncovering of Microbial Population Structures (GRUMPS): a reference free genomic data cleaning methodology
BrainSuite BIDS App：用于MRI分析的容器化工作流程	Kim, Y.	PDF	N/A	BrainSuite BIDS App: Containerized Workflows for MRI Analysis
分子动力学模拟揭示了序列背景在植物基于ELF3-PrD的温度感应机制中的作用	Lindsay, R. J.	PDF	N/A	Molecular dynamics simulations illuminate the role of sequence context in the ELF3-PrD-based temperature sensing mechanism in plants
人类装配体揭示了CACNA1G基因变异在丘脑皮质通路中的后果	Kim, J.-i.	PDF	N/A	Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway
多感官整合增强了Mauthner细胞的视听反应	Otero Coronel, S.	PDF	N/A	Multisensory integration enhances audiovisual responses in the Mauthner cell
追踪单细胞癌症3D基因组的演变：癌症基因发现的图谱	Liu, M.	PDF	N/A	Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery
在健康老化过程中，大脑对语义知识的表征呈现出增强的泛化和特化现象。	Margolles, P.	PDF	N/A	Enhanced generalization and specialization of brain representations of semantic knowledge in healthy aging
预期性脑活动依赖于预期刺激的感觉模式：单次试验分析的启示	Hoxha, I.	PDF	N/A	Anticipatory brain activity depends on the sensory modality of the expected stimulus: insights from single-trial analyses
去势模型在性别差异研究中的适用性：代谢组学和转录组学分析的启示	Jiang, J.	PDF	N/A	Applicability of Castration Model in Sex Difference Studies: Insights from Metabolome and Transcriptome Analyses
室管膜下区神经胶质生成调节脑缺血后胶质瘢痕处的细胞外基质	Ardaya, M.	PDF	N/A	Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia
MATES：一种基于深度学习的模型，用于单细胞中可移动元件的位点特异性定量	Wang, R.	PDF	N/A	MATES: A Deep Learning-Based Model for Locus-specific Quantification of Transposable Elements in Single Cell
翻译启动或延伸抑制在病原体感染期间对秀丽隐杆线虫生存产生对比效应	Ghosh, A.	PDF	N/A	Translation initiation or elongation inhibition triggers contrasting effects on Caenorhabditis elegans survival during pathogen infection
NF1相关外周神经鞘瘤的基因组特征：来自约翰斯·霍普金斯大学NF1生物样本库的队列分析	Banerjee, J.	PDF	N/A	Genomic features of NF1-associated peripheral nerve sheath tumors: a cohort analysis from the Johns Hopkins NF1 biospecimen repository
振幅压缩对注意神经语音追踪是有益还是阻碍？	Orf, M.	PDF	N/A	Does amplitude compression help or hinder attentional neural speech tracking?
CoCoPyE：用于学习和预测基因组质量指数的特征工程	Birth, N.	PDF	N/A	CoCoPyE: feature engineering for learning and prediction of genome quality indices
通过靶向染色质编辑揭示的模拟表观遗传记忆	Palacios, S.	PDF	N/A	Analog epigenetic memory revealed by targeted chromatin editing
开发一种实验协议，利用机器人技术和功能性磁共振成像研究手腕运动中力量和阻抗的神经控制	Schmidt, K.	PDF	N/A	Development of an Experimental Protocol to Study the Neural Control of Force and Impedance in Wrist Movements with Robotics and fMRI
已撤回：研究音乐在年轻成年人中诱发平静的能力。	Shepherd, D.	PDF	N/A	WITHDRAWN: Investigating the ability of music to induce calm in young adults.
CTFFIND5 提供了对 TEM 样本质量、倾斜度和厚度的更深入的见解。	Elferich, J.	PDF	N/A	CTFFIND5 provides improved insight into quality, tilt and thickness of TEM samples
化学诱导的衰老促使人类类小胶质细胞发生功能性变化	Armanville, S.	PDF	N/A	Chemically induced senescence prompts functional changes in human microglia-like cells
体积电子显微镜揭示了死后人类前额叶皮层中的三维突触纳米结构	Glausier, J. R.	PDF	N/A	Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex
调控网络结构对复杂性状遗传力和进化重要性的影响	Stone, K. L.	PDF	N/A	The Importance of Regulatory Network Structure for Complex Trait Heritability and Evolution
顺铂对蛋白质磷酸化的重编程	Qi, L.	PDF	N/A	Cisplatin reprogramming of protein phosphorylation
通过调节单个纳米颗粒蛋白质冠与小分子进行深度等离子体蛋白质组分析	Ashkarran, A. A.	PDF	N/A	Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules
长链非编码RNA Snhg3通过PPARγ信号通路加重肝脂肪变性	Xie, X.	PDF	N/A	LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARγ Signaling
通过系统评估化学数据的特性，为以数据为中心的虚拟药物筛选人工智能方法奠定基础	Chong, A.	PDF	N/A	Establishing the foundations for a data-centric AI approach for virtual drug screening through a systematic assessment of the properties of chemical data
紫胸木蜂（Xylocopa violacea，林奈，1785年）的基因组序列：一种正在扩展分布范围的膜翅目物种。	Nash, W.	PDF	N/A	The genome sequence of the Violet Carpenter Bee, Xylocopa violacea (Linnaeus, 1785): a hymenopteran species undergoing range expansion.
目标学习而非反向传播解释了哺乳动物新皮层中的学习过程	Aceituno, P. V.	PDF	N/A	Target Learning rather than Backpropagation ExplainsLearning in the Mammalian Neocortex
Atp1a2和Kcnj9是C57BL/6亚系中对羟考酮诱导的运动激活和戒断诱导的焦虑样行为敏感性的候选基因。	Goldberg, L. R.	PDF	N/A	Atp1a2 and Kcnj9 are candidate genes underlying sensitivity to oxycodone-induced locomotor activation and withdrawal-induced anxiety-like behaviors in C57BL/6 substrains
环境大肠杆菌中的喹诺酮抗性基因qnr、aac(6')-Ib-cr、oqxAB和qepA：通过比较基因组学对其遗传背景的洞察	Gomi, R.	PDF	N/A	Quinolone resistance genes qnr, aac(6')-Ib-cr, oqxAB, and qepA in environmental Escherichia coli: insights into their genetic contexts from comparative genomics
专家指导的蛋白质语言模型能够实现准确且极速的适应性预测	Marquet, C.	PDF	N/A	Expert-guided protein Language Models enable accurate and blazingly fast fitness prediction
表面脂质影响线虫发育和物种特异性化学信号传导	Kotowska, A. M.	PDF	N/A	Surface lipids influence developmental and species-specific chemical signalling in nematodes
细胞成像与化学结构跨域可以相互补充，用于在化学早期去风险中的大鼠急性口服毒性预测。	Camilleri, F.	PDF	N/A	Cell Painting and chemical structure read-across can complement each other for rat acute oral toxicity prediction in chemical early de-risking
CellSeg3D：用于光片显微镜的自监督3D细胞分割	Achard, C.	PDF	N/A	CellSeg3D: self-supervised 3D cell segmentation for light-sheet microscopy
间接遗传效应增加了可供选择的可遗传变异，并且对于行为来说这种效应最大：一项元分析	Santostefano, F.	PDF	N/A	Indirect genetic effects increase the heritable variation available to selection and are largest for behaviours: a meta-analysis
乐观和悲观的认知判断偏差调节斑马鱼的压力反应和癌症进展	Espigares, F.	PDF	N/A	Optimistic and pessimistic cognitive judgement bias modulates the stress response and cancer progression in zebrafish
放大双耳间电平差异可增强双侧耳蜗植入者从掩蔽中的空间释放	Richardson, B. N.	PDF	N/A	Magnified interaural level differences enhance spatial release from masking in bilateral cochlear implant users
表观遗传年龄模型在新一代甲基化阵列中的适用性	Garma, L. D.	PDF	N/A	Applicability of epigenetic age models to next-generation methylation arrays
中央觅食者、猎物耗竭光环以及行为性生态位分隔如何促进消费者共存	Rueffler, C.	PDF	N/A	Central place foragers, prey depletion halos, and how behavioral niche partitioning promotes consumer coexistence
在不进行额外训练或数据的情况下，提高逆折叠模型在蛋白质稳定性预测中的表现	Dutton, O.	PDF	N/A	Improving Inverse Folding models at Protein Stability Prediction without additional Training or Data
一种改进的四环素诱导型裂殖酵母表达系统	Lyu, X.-H.	PDF	N/A	An improved tetracycline-inducible expression system for fission yeast
在或外？利用高分辨率原子力显微镜追踪复杂DNA结构	Holmes, E. P.	PDF	N/A	Under or Over? Tracing Complex DNA Structures with High-Resolution Atomic Force Microscopy
物种形成完成率对宏观进化多样化的影响有限	Veron, P.	PDF	N/A	Speciation completion rates have limited impact on macroevolutionary diversification
CLEC18A与硫酸化的糖胺聚糖相互作用，并调控肾透明细胞癌的进展。	Jonsson, G.	PDF	N/A	CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression
哈茨木霉T22通过系统信号诱导根瘤菌和类黄酮，以对抗豌豆中的铁缺乏症。	Thapa, A.	PDF	N/A	Trichoderma afroharzianum T22 induces rhizobia and flavonoid through systemic signaling to combat Fe deficiency in garden pea
使用lr-kallisto进行长读长测序转录组定量	Loving, R. K.	PDF	N/A	Long-read sequencing transcriptome quantification with lr-kallisto
奖励历史引导胡须体感皮层的焦点注意	Ramamurthy, D. L.	PDF	N/A	Reward history guides focal attention in whisker somatosensory cortex
Lphn1基因敲除抑制结直肠癌机制的研究	wang, Y.	PDF	N/A	Research on the Mechanism of Lphn1 Knockout in Inhibiting Colorectal Cancer
对抗学习能够在大规模范围内实现单细胞RNA数据的跨物种无偏差全生物体对齐。	Cooper, S.	PDF	N/A	Adversarial learning enables unbiased organism-wide cross-species alignment of single-cell RNA data at scale
尿液多组学揭示了透明细胞肾细胞癌的非侵入性诊断生物标志物	Jonsson, G.	PDF	N/A	Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma
动态水凝胶交联强度控制着注射过程中的屈服特性和细胞活力	Eckman, N.	PDF	N/A	Dynamic Hydrogel Crosslink Strength Controls Yielding Characteristics and Cell Viability During Injection
单胺氧化酶C（MAO C）的进化与功能分析：MAO基因家族的新成员	Merello, G.	PDF	N/A	Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family
内生吡咯喹啉醌增强香蕉生长及对镰刀菌萎蔫病的免疫力，促进植物-微生物共生关系	Hung, S.-H. W.	PDF	N/A	Endophytic pyrroloquinoline quinone enhances banana growth and immunity against Fusarium wilt for plant-microbe mutualisms
深度逆向建模揭示了神经回路机制中的动态依赖不变性	Gao, R.	PDF	N/A	Deep inverse modeling reveals dynamic-dependent invariances in neural circuit mechanisms
BCL2L13 影响自噬和神经酰胺代谢，但不影响胶质母细胞瘤中的替莫唑胺耐药性	Clark, C.	PDF	N/A	BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma
BCV和（S）-HPMPA的新型衍生物比BCV更有效地抑制正痘病毒和人类腺病毒。	Zhang, Y.	PDF	N/A	Novel derivatives of BCV and (S)-HPMPA inhibit orthopoxviruses and human adenoviruses more potently than BCV
添加留尼汪岛节肢动物名录	Nibouche, S.	PDF	N/A	Additions to the list of arthropods of Reunion Island
特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了不同的运动障碍行为	Alcacer, C.	PDF	N/A	Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering
解码斑马鱼早期胚胎发育过程中细胞特异性转录异质性和可变剪接	Lin, X.	PDF	N/A	Deciphering the Cell Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish
解读斑马鱼早期胚胎发育过程中细胞特异性转录异质性和可变剪接	Lin, X.	PDF	N/A	Deciphering the Cell-Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish
肠道干细胞的增殖和分化依赖于锌指转录因子BCL11/Chronophage。	Redhai, S.	PDF	N/A	Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/Chronophage
杯状子叶2激活MIR319C转录并在拟南芥叶原基中促进细胞增殖	Alanga, N. S.	PDF	N/A	CUP-SHAPED COTYLEDON2 activates MIR319C transcription and promotes cell proliferation in Arabidopsis leaf primordia
在单倍体-二倍体植物马钱子（Marchantia polymorpha subsp. ruderalis）中，选择效力在不同生活阶段有所差异。	Shen, T.	PDF	N/A	Selection efficacy differs between lifestages in thehaploid-diploid Marchantia polymorpha subsp. ruderalis
模式工业产油微藻Nannochloropsis oceanica中碳浓缩机制的动态表观基因组景观	Gong, Y.	PDF	N/A	Dynamic epigenomic landscape of carbon-concentrating mechanisms in the model industrial oleaginous microalga Nannochloropsis oceanica
一种结合基因组和外显子组测序的方法能够以无偏差、高质量且经济高效的方式捕获遗传变异。	Boltz, T. A.	PDF	N/A	A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner
金黄色叙利亚仓鼠（Mesocricetus auratus）作为一种模型，用于解析与绵羊相关恶性卡他热的相关致病方面。	Fabian, R.	PDF	N/A	The golden Syrian hamster (Mesocricetus auratus) as a model to decipher relevant pathogenic aspects of sheep-associated malignant catarrhal fever
甲基磺酰甲烷：一种针对胶质母细胞瘤多形性中涉及的鞘氨醇激酶1的潜在膳食补充剂	Ahmad, F.	PDF	N/A	Methylsulfonylmethane: A Potential Dietary Supplement targeting sphingosine kinase 1 involved in Glioblastomamultiforme
巴基斯坦临床肺炎克雷伯菌中携带blaNDM-1、-5、-7碳青霉烯酶基因的质粒基因组特征分析	Qamar, M. U.	PDF	N/A	Genomic characterization of plasmids harboring blaNDM-1,-5,-7 carbapenemase alleles in clinical Klebsiella pneumoniae in Pakistan
光化学过程驱动深海中溶解有机物的温度响应	Hu, A.	PDF	N/A	Photochemical processes drive thermal responses of dissolved organic matter in the dark ocean
理解产生侧捏运动的大拇指肌肉小群：应用于神经损伤后抓握功能的手术修复	Smith, C. D.	PDF	N/A	Toward an understanding of the small groups of thumb muscles that produce lateral pinch movement: application to surgical restoration of grasp following neurologic impairment
MaskMol：用于活性悬崖的像素掩码知识引导分子图像预训练框架	cheng, Z.	PDF	N/A	MaskMol: Knowledge-guided Molecular Image Pre-Training Framework for Activity Cliffs with Pixel Masking
利用RNA-seq解析羽扇豆（Lupinus angustifolius）种子发育过程中的转录编程	WAINAINA, V.	PDF	N/A	Deciphering transcriptional programming during lupin (Lupinus angustifolius) seed development using RNA-seq
根据三维形态测量学见解，田鼠亚科啮齿动物（Rodentia）颅骨的演化：第一部分。腭蝶翼骨复合体的形态差异	Voyta, L. L.	PDF	N/A	Evolution of the skull in arvicoline cricetids (Rodentia) according to 3D morphometric insights: Part 1. Morphological disparity of the palato-spheno-pterygoid complex
在发育过程中恢复短暂连接性可改善脆性X小鼠的功能障碍	Dumontier, D.	PDF	N/A	Restoring transient connectivity during development improves dysfunctions in fragile X mice
高分辨率fMRI中的模糊波纹伪影：识别、成因及缓解方法	Huber, L.	PDF	N/A	Fuzzy ripple artifact in high resolution fMRI: identification, cause, and mitigation
在创意讲故事过程中，创意生成与评估之间存在动态循环	Liang, X.	PDF	N/A	Dynamic cycles between idea generation and evaluation during creative storytelling
功能性见解：全球野化对猫肠道微生物群的影响	Aizpurua, O.	PDF	N/A	Functional insights into the effect of feralisation on the gut microbiota of cats worldwide
对全球范围内野化对猫肠道微生物群影响的功能性见解	Aizpurua, O.	PDF	N/A	Functional insights into the effect of feralisation on the gut microbiota of cats worldwide
南非现存最大规模的蓝角马（Connochaetes taurinus taurinus）迁徙种群的遗传多样性与种群历史	Szarmach, S.	PDF	N/A	Genetic diversity and demographic history of the largest remaining migratory population of blue wildebeest (Connochaetes taurinus taurinus) in southern Africa
南非现存最大规模的蓝角马（Connochaetes taurinus taurinus）迁徙种群的遗传多样性与种群历史	Szarmach, S.	PDF	N/A	Genetic diversity and demographic history of the largest remaining migratory population of blue wildebeest (Connochaetes taurinus taurinus) in southern Africa
一种稳健的无监督聚类方法用于高维生物成像数据，揭示了共享的药物诱导形态特征	Bao, S. C.	PDF	N/A	A robust unsupervised clustering approach for high-dimensional biological imaging data reveals shared drug-induced morphological signatures
水杨酸抑制细胞伸长并诱导液泡形态和pH值的变化。	Mueller, J.	PDF	N/A	Salicylic Acid restricts cell elongation and induces changes of vacuolar morphology and pH
细胞骨架破坏对质膜受体动力学的对比效应：来自单分子分析的见解	Rohr, L.	PDF	N/A	Contrasting Effects of Cytoskeleton Disruption on Plasma Membrane Receptor Dynamics: Insights from Single-Molecule Analyses
改变拟南芥的糖代谢会影响分泌物、免疫反应以及植物与微生物的相互作用	Siffert, A.	PDF	N/A	Altered Arabidopsis thaliana sugar metabolism affects exudation, immune responses, and plant-microbe interactions
细胞几何结构、微管锚定及各向异性的动态不稳定性：横向皮质阵列组织的挑战与解决方案	Tian, T. Y. Y.	PDF	N/A	Cell geometry, microtubule anchoring and anisotropic dynamic instability: challenges and solutions to transverse cortical array organization
跨物种相互作用组分析揭示了植物中一种保守的选择性自噬机制，用于蛋白质质量控制	Hernandez, V. S. d. M.	PDF	N/A	Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants
停止速度作为状态而非特质：探究多轮停止信号任务中动物间停止速度的差异	ter Horst, J.	PDF	N/A	Stopping Speed as State, Not Trait: Exploring Within-Animal Varying Stopping Speeds in a Multi-Session Stop-Signal Task
视觉逃避习惯化中个体差异的神经回路	Liu, X.	PDF	N/A	Neural Circuit Underlying Individual differences in Visual Escape Habituation
HHIP在表皮伤口愈合中的动态作用揭示了COPD易感性的潜在机制	Deritei, D.	PDF	N/A	HHIP's Dynamic Role in Epithelial Wound Healing Reveals a Potential Mechanism of COPD Susceptibility
马拉维分离株中T. b. rhodesiense血清抗性相关基因的遗传多样性	Nambala, P.	PDF	N/A	GENETIC DIVERSITY OF T. B. RHODESIENSE SERUM RESISTANCE ASSOCIATED GENE IN MALAWIAN ISOLATES
等位基因特异性表达在肿瘤发生过程中被选择，源于表观遗传变化，并与预后相关。	Palou-Marquez, G.	PDF	N/A	Allele-specific expression is selected in tumorigenesis, results from epigenetic changes and has prognostic relevance
15基因预后特征，其中TFAP2B在卵巢癌铂耐药中发挥作用	Hu, Y.	PDF	N/A	A 15-Gene prognostic signature with TFAP2B functioning in Platinum Resistance of Ovarian Carcinoma
进化与生命在多个粒度上的分支紧密相连。	Douglas, J.	PDF	N/A	Evolution is coupled with branching across many granularities of life
一种基于胍的冠状病毒复制抑制剂，靶向nsp15内切核糖核酸酶，结合了直接的抗病毒效果与微妙的干扰素增强作用。	Van Loy, B.	PDF	N/A	A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and combines a direct antiviral effect with subtle boosting of interferon
CRISPR-CLEAR：通过平铺碱基编辑的等位基因读出实现调控元件的核苷酸分辨率映射	Becerra, B.	PDF	N/A	CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing
与AK2A的相互作用将AIFM1与细胞能量代谢联系起来	Rothemann, R. A.	PDF	N/A	Interaction with AK2A links AIFM1 to cellular energy metabolism
选择性氘化RNA:RNA复合物用于结构分析的小角散射	Munsayac, A.	PDF	N/A	Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering
磷脂酰肌醇聚焦的CRISPR筛选识别出胰腺导管腺癌（PDAC）和急性髓系白血病（AML）细胞中的新型遗传脆弱性	Lee, D. K.	PDF	N/A	Phosphoinositide-focused CRISPR screen identifies novel genetic vulnerabilities in PDAC and AML cells
长期热应激增强蚊子对病毒感染的耐受性	Perdomo, H. D.	PDF	N/A	Prolonged thermal stress enhances mosquito tolerance to viral infection
Kinbiont：从时间序列到微生物系统中的生态和进化响应	Angaroni, F.	PDF	N/A	Kinbiont: From time series to ecological and evolutionary responses in microbial systems
铜绿假单胞菌在呼吸道感染期间面临一种适应性权衡，即在黏膜定植与抗生素耐受性之间做出选择。	Meirelles, L. A.	PDF	N/A	Pseudomonas aeruginosa faces a fitness trade-off between mucosal colonization and antibiotic tolerance during airway infections
通过拓扑约束分子生成模型发现针对COVID-19的新型喹啉类木瓜蛋白酶样蛋白酶抑制剂	Shang, J.	PDF	N/A	Discovery of novel quinoline papain-like protease inhibitors for COVID-19 through topology constrained molecular generative model
通过蛋白质组学检测ESKAPE病原体的抗生素抗性并同时鉴定其物种	Blumenscheit, C.	PDF	N/A	Antibiotic resistance detection and concomitant species identification of ESKAPE pathogens by proteomics
利用PREDAC模型模拟季节性流感病毒的抗原进化，以在2025年季节中选择疫苗株	Peng, Y.	PDF	N/A	Modeling the antigenic evolution of seasonal influenza viruses with PREDAC for vaccine strain selection in the season of 2025
利用CRISPR-Cas13d在诱导性敲降系统中研究果蝇生殖颗粒mRNA	Gauhar, Z. A.	PDF	N/A	Leveraging CRISPR-Cas13d in an inducible knockdown system to interrogate Drosophila germ granule mRNAs
SIRT6缺失通过促进衰老和SASP状态导致小鼠椎间盘退变	Ramteke, P.	PDF	N/A	SIRT6 loss causes intervertebral disc degeneration in mice by promoting senescence and SASP status
拟南芥tRNA氨基酸化作用的景观	Ceriotti, L. F.	PDF	N/A	The landscape of Arabidopsis tRNA aminoacylation
高质量的肽段证据用于注释非规范开放阅读框为人类蛋白质	Deutsch, E. W.	PDF	N/A	High-quality peptide evidence for annotating non-canonical open reading frames as human proteins
高吞吐量酶促DNA甲基化测序的经济高效解决方案	Longtin, A.	PDF	N/A	Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing
转录因子网络对血液细胞表型的遗传性具有不成比例的富集作用	Martin-Rufino, J. D.	PDF	N/A	Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes
将新开发的SNP条形码面板与微卫星进行比较，以探索秘鲁亚马逊地区疟疾病原体的群体遗传学	Cabrera-Sosa, L.	PDF	N/A	Comparing newly developed SNP barcode panels with microsatellites to explore population genetics of malaria parasites in the Peruvian Amazon
一种致病突变如何从单体到完全组装状态损害Hsp60的功能动态	Torielli, L.	PDF	N/A	How a pathogenic mutation impairs Hsp60 functional dynamics from monomeric to fully assembled states
一种与能量平衡相关的次级β-羟基丁酸代谢途径	Moya-Garzon, M. D.	PDF	N/A	A secondary β-hydroxybutyrate metabolic pathway linked to energy balance
通过FeII/2-氧代戊二酸依赖的双加氧酶进行非耦合琥珀酸生产的比较分析	Das, S.	PDF	N/A	Comparative analysis of uncoupled succinate production by the FeII/2-oxoglutarate-dependent dioxygenases
尿酸在人类URAT1中的转运机制及促尿酸排泄药物的抑制作用	Guo, W.	PDF	N/A	Mechanisms of urate transport and uricosuric drugs inhibition in human URAT1
人类心脏类器官的成熟对于疾病建模和药物发现是必要的。	Pocock, M.	PDF	N/A	Maturation of human cardiac organoids are required for disease modelling and drug discovery
结核分枝杆菌拓扑异构酶IA在C端缺失的情况下会遭受能量上的困扰	Balthrop, D.	PDF	N/A	Mycobacterial Topoisomerase IA Energetically Suffers From C-terminal Deletions
CRISPRoff表观遗传编辑：在人类细胞中实现可编程基因沉默，无需DNA断裂	Pattali, R. K.	PDF	N/A	CRISPRoff epigenetic editing for programmable gene silencing in human cells without DNA breaks
昆虫宿主中功能性微生物植酸酶的生物制造。	Retief, C.	PDF	N/A	Biomanufacturing of a functional microbial phytase in an insect host.
使用中尺度透析系统在PURE中实现长期蛋白质合成	Julia, L. R.	PDF	N/A	Long-term protein synthesis with PURE in a mesoscale dialysis system
跨物种全脑映射揭示了由伏隔核深部脑刺激所激活的保守且协调的神经网络	Feng, A.	PDF	N/A	Cross-species brain-wide mapping reveals a conserved and coordinated network engaged by NAc DBS
通过双向循环门控建模大脑中的注意力和绑定机制	Salehinajafabadi, S.	PDF	N/A	Modeling Attention and Binding in the Brain through Bidirectional Recurrent Gating
光感受器退化对功能性视网膜神经节细胞类型产生异质性影响	Dyszkant, N.	PDF	N/A	Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types
毛圆蛛（Uloborus diversus）大脑的三维免疫荧光图谱。	Artiushin, G.	PDF	N/A	A three-dimensional immunofluorescence atlas of the brain of the hackled-orb weaver spider, Uloborus diversus.
在巨细胞核中存在α-突触核蛋白聚集的前驱性突触核病模型中，运动迟缓和姿势不稳定的症状。	Theologidis, V.	PDF	N/A	Bradykinesia and postural instability in a model of prodromal Synucleinopathy with alpha-Synuclein aggregation in the gigantocellular nuclei.
非麻痹手臂的使用反映了慢性中风患者的一种习惯性行为。	Sporn, S.	PDF	N/A	Use of the non-paretic arm reflects a habitual behaviour in chronic stroke
健康供体与急性移植物抗宿主病患者T细胞反应的比较评估：定制免疫监测平台	Mendiratta, M.	PDF	N/A	A Comparative assessment of T-Cell response of Healthy donors and Acute Graft-versus-Host-Disease Patients: Customizing immune monitoring platform
从家养和野生动物中分离出的Trueperella pyogenes的基因组和代谢特征分析	Magossi, G.	PDF	N/A	Genomic and metabolic characterization of Trueperella pyogenes isolated from domestic and wild animals
冷冻电镜揭示了RNA聚合酶I在无碱基DNA损伤处暂停和停滞的顺序机制	Santos-Aledo, A.	PDF	N/A	Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions
膜结合的钙粘蛋白底物揭示了粘着连接处的肌动蛋白结构	Ghosh, S.	PDF	N/A	Membrane-tethered cadherin substrates reveal actin architecture at adherens junctions
人类肺部神经内分泌细胞对屋尘螨提取物产生反应，通过PAR-1依赖性途径释放CGRP。	Mann-Nuttel, R.	PDF	N/A	Human pulmonary neuroendocrine cells respond to House dust mite extract with PAR-1 dependent release of CGRP
Rho-ROCK释放被隔离的claudin，以促进新紧密连接的快速形成	Cho, Y.	PDF	N/A	Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation
癌症中新型潘尼克斯1异构体表达增加	O'Donnell, B. L.	PDF	N/A	Novel Pannexin 1 isoform is increased in cancer
中期形成初期的早期事件稳定了新生成的双极纺锤体	Sim, S.	PDF	N/A	Early events in midzone formation stabilize nascent bipolar spindles
平衡肌动蛋白网络竞争中的有限资源	Guerin, C.	PDF	N/A	Balancing limited resources in actin networks competition
电子冷冻断层扫描揭示了纤毛内连接的结构	Li, S.	PDF	N/A	The Structure of Cilium Inner Junctions Revealed by Electron Cryo-tomography
Maspin/SerpinB5是一种细胞骨架结合蛋白，能够调控上皮细胞的形态。	da Silva, L.	PDF	N/A	Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape
间歇性缺氧通过依赖活性氧的机制增加H3K27乙酰化，这一过程受H3S28磷酸化的调控。	Nanduri, J.	PDF	N/A	Reactive Oxygen species dependent increase in H3K27 acetylation by intermittent hypoxia is regulated by H3S28 phosphorylation
哺乳动物肺纤维化中的神经-成纤维细胞轴	Ishikawa, G.	PDF	N/A	A Nerve-Fibroblast Axis in Mammalian Lung Fibrosis
促性腺激素细胞具有双重起源，其中大多数在微青春期期间源自垂体干细胞。	Sheridan, D.	PDF	N/A	Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty.
引入的鳟鱼阻碍了本地鱼类在极端洪水干扰后的恢复	Lennox, R. S.	PDF	N/A	Introduced trout hinder the recovery of native fish following an extreme flood disturbance
学龄前音乐性通过与节奏性相关的基因与学龄期沟通能力相关联。	de Hoyos, L.	PDF	N/A	Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity
VCP（一种重要的解旋酶）与去泛素酶之间不同的耦合模式	Vostal, L. E.	PDF	N/A	Distinct modes of coupling between VCP, an essential unfoldase, and deubiquitinases
在搅拌罐生物反应器中，胰腺β细胞的外泌体三步可扩展生产促进了细胞成熟及具有保留免疫调节特性的外泌体释放。	De Beaurepaire, L.	PDF	N/A	Three-step scalable production of extracellular vesicles from pancreatic beta cells in stirred tank bioreactors promotes cell maturation and release of ectosomes with preserved immunomodulatory properties
BFVD - 一个预测病毒蛋白质结构的大型数据库	Steinegger, M.	PDF	N/A	BFVD - a large repository of predicted viral protein structures
利用CellMATE解锁单细胞与空间联合分析的跨模态互动	Jingping, Y.	PDF	N/A	Unlocking cross-modal interplay of single-cell and spatial joint profiling with CellMATE
估计2022/24年高致病性禽流感病毒传入美国各商业禽群的适当接触率和时间	Ssematimba, A.	PDF	N/A	Estimating adequate contact rates and time of Highly Pathogenic Avian Influenza virus introduction into individual United States commercial poultry flocks during the 2022/24 epizootic
全血生理应激引起的可逆转录组年龄变化	Bhak, J.	PDF	N/A	Reversible Transcriptomic Age Shifts from Physiological Stress in Whole Blood
肌钙蛋白-C突变谱中的钙结合亲和力：自由能计算、协同进化建模与机器学习	Pooja,	PDF	N/A	Calcium Binding Affinity in the Mutational Landscape of Troponin-C: Free Energy Calculation, Co-evolution modeling and Machine Learning
三阴性乳腺癌患者来源的异种移植模型中，线粒体的三维分析揭示了化疗治疗后线粒体网络的重塑	Berner, M. J.	PDF	N/A	Three-dimensional analysis of mitochondria in a patient-derived xenograft model of triple negative breast cancer reveals mitochondrial network remodeling following chemotherapy treatments
通过ZenoTOF技术进行的定量特异性糖蛋白质组学揭示了用于乳腺癌诊断的糖基特征	Yang, Y.	PDF	N/A	Quantitative site-specific glycoproteomics by ZenoTOF reveals glyco-signatures for breast cancer diagnosis
细胞外囊泡通过将ATP合成转运至伪足并激活整合素粘附复合物，调控淋巴管平滑肌瘤细胞的亚稳态表型。	Kalvala, A. K.	PDF	N/A	Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes.
在神经纤维瘤病1型中，正常组织中的与癌症无关的第二次体细胞NF1突变	Oliver, T. R. W.	PDF	N/A	Cancer-independent, second somatic NF1 mutation of normal tissues in neurofibromatosis type 1
NR2F2在早期脂肪细胞干细胞样细胞中的再激活可挽救脂肪细胞线粒体氧化	Das, S.	PDF	N/A	NR2F2 Reactivation in Early-life Adipocyte Stem-like Cells Rescues Adipocyte Mitochondrial Oxidation
HYCCIN2通过招募SH3P2-DRP1A驱动拟南芥胚胎细胞板形成中的膜管化	Hsu, Y.-w.	PDF	N/A	Recruitment of SH3P2-DRP1A by HYCCIN2 Drives Membrane Tubulation in Arabidopsis Embryonic Cell Plate Formation
雌激素受体α介导的PRICKLE1抑制作用破坏了REST的稳定性，并促进了子宫肌瘤的发病机制。	McWilliams, M. M.	PDF	N/A	Estrogen receptor alpha mediated repression of PRICKLE1 destabilizes REST and promotes uterine fibroid pathogenesis
Osterix通过靶向连接蛋白43促进骨细胞间的通讯	wu, z.	PDF	N/A	Osterix Facilitates Osteocytic Communication by Targeting Connexin43
SAF-A SAP结构域在X染色体失活、转录、剪接和细胞增殖中的作用	Sharp, J. A.	PDF	N/A	Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation
突触前神经元是线粒体自噬的驿站，能防止轴突退化。	Lam, W. K.	PDF	N/A	Presynapses are mitophagy pit stops that prevent axon degeneration
力量变异性可能是半球中风幸存者运动障碍的潜在生物标志物。	Shi, F.	PDF	N/A	Force variability is a potential biomarker of motor impairment in hemispheric stroke survivors
帕金森病患者中有一小部分人的骨骼肌出现了线粒体复合物I缺陷。	Kverneng, S. U.	PDF	N/A	Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson's disease
# BioRxiv 2024-09-08 Papers

标题	作者	PDF链接	代码仓库	Title
局部矿物稳态的变化促进了良性和恶性睾丸微钙化的形成。	Boisen, I. M.	PDF	N/A	Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications
在概率奖励学习过程中，通过小鼠内侧前额叶皮层进行的变化点估计	Murphy, C. E.	PDF	N/A	Change point estimation by the mouse medial frontal cortex during probabilistic reward learning
基于大肠杆菌的细胞无细胞系统中的代谢扰动揭示了转录与翻译之间的权衡关系	Kapasiawala, M.	PDF	N/A	Metabolic perturbations to an E. coli-based cell-free system reveal a trade-off between transcription and translation
贝阿特丽斯：使用深度变分推断从摘要数据进行贝叶斯精细定位	Ghosal, S.	PDF	N/A	BEATRICE: Bayesian Fine-mapping from Summary Datausing Deep Variational Inference
如果……会怎样？小脑皮质颗粒层的计算解剖学	Gilbert, M.	PDF	N/A	What if...? Computational anatomy in the granular layer of the cerebellar cortex
对费氏弧菌中环二鸟苷酸调节蛋白的功能分析	Isenberg, R. Y.	PDF	N/A	Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri
大脑在多步骤预测过程中，会分层次地表征过去和未来。	Tarder-Stoll, H.	PDF	N/A	The brain hierarchically represents the past and future during multistep anticipation
体质人类学研究中主成分分析（PCA）的偏见需要重新评估进化见解	Mohseni, N.	PDF	N/A	Biases of Principal Component Analysis (PCA) in Physical Anthropology Studies Require a Reevaluation of Evolutionary Insights
早期生活逆境对压力反应性的性别特异性和发育影响可通过出生后敲低5-HT1A自身受体得到挽救	Dixon, R.	PDF	N/A	Sex-specific and Developmental Effects of Early Life Adversity on Stress Reactivity are Rescued by Postnatal Knockdown of 5-HT1A Autoreceptors
APP调控因子RHBDL4的丢失在阿尔茨海默病小鼠模型中保护了记忆。	Penalva, Y. C. M.	PDF	N/A	Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model.
膜泡可以通过船蛆的可培养胞内共生体Teredinibacter turnerae促进纤维素降解。	Gasser, M. T.	PDF	N/A	Membrane vesicles can contribute to cellulose degradation by Teredinibacter turnerae, a cultivable intracellular endosymbiont of shipworms
虚拟现实课堂中的选择性注意与听觉干扰敏感性：AD(H)D成人与非AD(H)D成人的比较	Levy, O.	PDF	N/A	Selective attention and sensitivity to auditory disturbances in a virtually-real Classroom: Comparison of adults with and without AD(H)D
藤蔓衰退病对西瓜果实氨基酸代谢的影响	Santo, H.	PDF	N/A	Influence of vine decline disease on the amino acid metabolism of watermelon fruit
先前未测量的遗传多样性解释了基于k-mer的112种植物物种元分析中莱文廷悖论的部分内容	Roberts, M. D.	PDF	N/A	Previously unmeasured genetic diversity explains part of Lewontin's paradox in a k-mer-based meta-analysis of 112 plant species
发育中的高级皮层中，相关自发性活动建立了多感官整合	Dwulet, J. M.	PDF	N/A	Correlated spontaneous activity sets up multi-sensory integration in the developing higher-order cortex
组胺干扰了小鼠的早期视觉处理	Tripodi, M.	PDF	N/A	Histamine interferes with the early visual processing in mice
大型齿鲸种内体型变异的总结	McClure, J.	PDF	N/A	A summary of intraspecific size variation for large odontocetes
结构蛋白质组学揭示了孕酮受体的顺序启动机制	Mann, M. D.	PDF	N/A	Structural proteomics defines a sequential priming mechanism for the progesterone receptor
结构稳定性决定了互利共生模型生态系统中的进化稳定性	Lurgi, M.	PDF	N/A	Structural stability determines evolutionary stability in mutualistic model ecosystems
连接牙冠：分析现代人类后臼齿的形态协变	Simkova, P. G.	PDF	N/A	Connecting crowns: Analyzing morphological covariation in the modern human postcanine dentition
每个速率类别独立碱基组成的改进似然性系统发育估计：5rf模型	Waddell, P. J.	PDF	N/A	An independent base composition of each rate class for improved likelihood-based phylogeny estimation: The 5rf model
穴样蛋白-1和机械应力调控具有促转移作用的小型细胞外囊泡亚群的释放	Saquel, C.	PDF	N/A	Caveolin-1 and mechanical stress control the release of a pro-metastatic subpopulation of small extracellular vesicles
单核多组学揭示了皮克氏病和阿尔茨海默病中共享及独特的通路	Shi, Z.	PDF	N/A	Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease
在小鼠生命全程中，对少突胶质细胞组织和少突胶质细胞生成的全脑图谱分析	Xu, Y. K. T.	PDF	N/A	Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan
在癫痫和智力障碍的人脑类器官模型中模拟皮层与海马网络功能障碍	McCrimmon, C. M.	PDF	N/A	Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability
内吞素A1促进GABA能突触后机制的组织，以维持兴奋-抑制平衡	Chen, X.	PDF	N/A	Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance
一种依赖于多巴胺的机制，用于奖励诱导的恐惧记忆的修改	Kong, M.-S.	PDF	N/A	A dopamine-dependent mechanism for reward-induced modification of fear memories
典型的突触和神经元特性的发育可以在没有小胶质细胞的情况下进行。	O'Keeffe, M.	PDF	N/A	Typical development of synaptic and neuronal properties can proceed without microglia
从Cercis canadensis和Chamaecrista fasciculata基因组推断出的豆科基因组结构和历史	Lee, H.-o.	PDF	N/A	Legume genome structures and histories inferred from Cercis canadensis and Chamaecrista fasciculata genomes
在100 keV能量下通过单颗粒冷冻电镜确定亚3 Å分辨率的蛋白质结构	Karia, D.	PDF	N/A	Sub-3 A resolution protein structure determination by single-particle cryo-EM at 100 keV
未管理蜜蜂群落（Apis mellifera carnica）在森林环境中的蜂群活动率和活动时间	Rutschmann, B.	PDF	N/A	Swarming rate and timing of unmanaged honeybee colonies (Apis mellifera carnica) in a forest environment
按蚊属物种复合体内味觉受体的分子进化	Popkin-Hall, Z. R.	PDF	N/A	Molecular Evolution of Gustatory Receptors in the Anopheles gambiae Species Complex
detectEVE：在基因组数据中快速、灵敏且精确地检测内源性病毒元素	Brait, N.	PDF	N/A	detectEVE: fast, sensitive and precise detection of endogenous viral elements in genomic data
NetMedPy：一个用于大规模网络医学筛选的Python包	Aldana, A.	PDF	N/A	NetMedPy: A Python package for Large-Scale Network Medicine Screening
质子结合的变构调节赋予囊泡谷氨酸转运蛋白氯离子活化和谷氨酸选择性	Borghans, B.	PDF	N/A	Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters
TCV的衣壳蛋白通过泛素化和自噬途径抑制RNA降解，从而促进病毒感染。	Wu, K.	PDF	N/A	Coat protein of TCV suppresses RNA decay via ubiquitination and autophagy pathways to facilitate viral infection
全面表征BTK抑制剂的特异性、效力和生物效应：对共价和非共价机制特征的深入见解	Darragh, A. C.	PDF	N/A	Comprehensive Characterization of BTK Inhibitor Specificity, Potency, and Biological Effects: Insights into Covalent and Non-covalent Mechanistic Signatures
基因组组成预测多倍体蝾螈对环境变化的生理反应	Burger, I.	PDF	N/A	Genome composition predicts physiological response to environmental change in polyploid salamanders
叶绿体中磷脂酰肌醇（PPIs）的存在与功能的最新证据	Sedaghatmehr, M.	PDF	N/A	New evidence for the presence and function of phosphoinositides (PPIs) in the chloroplast
特定纹状体神经元群的异常过度活跃通过高分辨率聚类揭示了不同的运动障碍行为	Alcacer, C.	PDF	N/A	Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering
使用潜在类线性混合模型改进了间歇性获取两瓶选择大鼠模型中酒精摄入组的分类	Angeles-Valdez, D.	PDF	N/A	Improved classification of alcohol intake groups in the Intermittent-Access Two-Bottle choice rat model using a latent class linear mixed model
特定特征的区分归一化改进了深度感知中自然图像的编码	Ni, L.	PDF	N/A	Feature-specific divisive normalization improves natural image encoding for depth perception
通过表观遗传调控与免疫检查点抑制的联合作用增强HBV特异性T细胞反应	Urbanek-Quaing, M.	PDF	N/A	Enhancing HBV-specific T cell responses through a combination of epigenetic modulation and immune checkpoint inhibition
野生动物的供给选择使宿主中不完全免疫的病原体毒性更高。	Walsman, J. C.	PDF	N/A	Wildlife provisioning selects for higher pathogen virulence in hosts with incomplete immunity
杀伤性病毒感染对野生酿酒酵母的适应性影响	Unni, R.	PDF	N/A	Fitness effects of killer virus infection on wild Saccharomyces paradoxus
利用单粒近红外光谱技术和基因组选择进行表型组选择，以改进玉米育种	Prado Graciano, R.	PDF	N/A	Integrating Phenomic Selection Using Single-Kernel Near-Infrared Spectroscopy and Genomic Selection for Corn Breeding Improvement
探索破裂的人类股四头肌肌腱在单细胞分辨率下的细胞变化	Mimpen, J. Y.	PDF	N/A	Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution
模块化光稳定荧光DNA块剖析病原体突变驱动蛋白对集体运输的影响	Kita, T.	PDF	N/A	Modular photostable fluorescent DNA blocks dissect the effects of pathogenic mutant kinesin on collective transport
mRNA密码子序列的深度生成优化，以提高蛋白质产量和治疗效果	Li, Y.	PDF	N/A	Deep Generative Optimization of mRNA Codon Sequences for Enhanced Protein Production and Therapeutic Efficacy
在蛋白质约束模型中整合混杂酶活性，揭示了地下代谢在代谢表型稳健性中的作用	de Moura Ferreira, M. A.	PDF	N/A	Integrating promiscuous enzyme activities in protein-constrained models pinpoints the role of underground metabolism in robustness of metabolic phenotypes
二光子驱动的虾青素功能化橙色类胡萝卜素蛋白光保护机制	Nizinski, S.	PDF	N/A	Two-photon driven photoprotection mechanism in echinenone-functionalized Orange Carotenoid Protein
葡萄糖限制对癌症细胞收缩性的影响：U-87胶质瘤中的阈值反应	Kong, A.	PDF	N/A	The effect of glucose restriction on cancer cell contractility: A threshold response in U-87 glioma
利用非扩散性邻近标记系统在活细胞和生物体内鉴定目标蛋白质	Sun, Y.	PDF	N/A	Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
InCO的移码突变可能导致日本牵牛花的早花现象，并可能促成了其向北扩张。	Katsuyama, H.	PDF	N/A	Frame-shift mutation of InCO might cause early flowering of Japanese morning glory and might have contributed to northward expansion
解决珊瑚微生境和礁石生态位中Symbiodiniaceae多样性问题	Million, W.	PDF	N/A	Resolving Symbiodiniaceae diversity across coral microhabitats and reef niches
成对C型凝集素受体介导秀丽隐杆线虫对不同卵菌病原体的特异性识别。	Liu, K.	PDF	N/A	Paired C-type lectin receptors mediate specific recognition of divergent oomycete pathogens in C. elegans.
在大量开花期间，地中海果园中管理的熊蜂溢出对生态系统造成了轻微的短期影响。	Nachtom Catalan, N.	PDF	N/A	Spillover of managed bumble bees from Mediterranean orchards during mass flowering causes minor short-term ecological impacts
通过祖先序列重建研究酶的低温适应性	Cui, S.	PDF	N/A	Insights into the low-temperature adaptation of an enzyme as studied through ancestral sequence reconstruction
DupLoss-2：在基因重复和丢失条件下改进的系统基因组物种树推断	Parsons, R.	PDF	N/A	DupLoss-2: Improved Phylogenomic Species Tree Inference under Gene Duplication and Loss
鼠标脑提取器：利用全局位置编码和SwinUNETR进行鼠标MRI的脑部分割	Kim, Y.	PDF	N/A	Mouse Brain Extractor: Brain segmentation of mouse MRI using global positional encoding and SwinUNETR
学生自我调节会调节皮层兴奋性和皮层唤醒的标志物。	Weijs, M. L.	PDF	N/A	Pupil self-regulation modulates markers of cortical excitability and cortical arousal
电极流形上睡眠慢振荡出现的预测建模：迈向个性化闭环脑刺激	Alipour, M.	PDF	N/A	Predictive Modeling of Sleep Slow Oscillation Emergence on the electrode manifold: Toward Personalized Closed-Loop Brain Stimulation
一种用于功能性免疫细胞疗法微尺度生产的数字微流控平台	Little, S. R.	PDF	N/A	A Digital Microfluidic Platform for the Microscale Production of Functional Immune Cell Therapies
一种用于在多重图像中分割细胞和细胞核的新型通道不变架构，采用InstanSeg技术。	Goldsborough, T.	PDF	N/A	A novel channel invariant architecture for the segmentation of cells and nuclei in multiplexed images using InstanSeg
作物育种中基因组预测的集成方法预测性能的改进	Tomura, S.	PDF	N/A	Improvements in Prediction Performance of Ensemble Approaches for Genomic Prediction in Crop Breeding
细菌细胞壁的非线性应力软化特性赋予了细胞形状的稳态维持能力。	Bardetti, P.	PDF	N/A	Non-linear stress-softening of the bacterial cell wall confers cell shape homeostasis
细菌转录抑制因子NrdR - 一种灵活的多因素核苷酸传感器	Rozman Grinberg, I.	PDF	N/A	Bacterial transcriptional repressor NrdR - a flexiblemultifactorial nucleotide sensor
类似自然语言处理的深度学习辅助在多种细菌中识别和验证硫代磺酸酯耐受性集群	Myers, B. K.	PDF	N/A	Natural Language Processing-like Deep Learning Aided in Identification and Validation of Thiosulfinate Tolerance Clusters in Diverse Bacteria
MYO5B缺陷引起的细胞代谢途径改变和上皮细胞成熟过程可以通过LPAR5激活部分逆转。	Momoh, M.	PDF	N/A	Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation
刺激重复在初级视觉皮层中引发了一个两阶段的学习过程。	Cui, L.	PDF	N/A	Stimulus repetition induces a two-stage learning process in primary visual cortex
DAR-901和BCG诱导的对抗鸟分枝杆菌的免疫	Abate, G.	PDF	N/A	Immunity against Mycobacterium avium induced by DAR-901 and BCG
在原核腺苷酸激酶的热适应过程中，灵活性的变化而非紧密性的变化是其基础。	Kontopoulos, D. - G.	PDF	N/A	Changes in flexibility but not in compactness underlie the thermal adaptation of prokaryotic adenylate kinases
作为治疗囊性纤维化的方法，子宫内全身基因编辑	Ricciardi, A. S.	PDF	N/A	Systemic in utero gene editing as a treatment for cystic fibrosis
NiCo通过微环境协变分析识别细胞状态调控的外在驱动因素	Agrawal, A.	PDF	N/A	NiCo Identifies Extrinsic Drivers of Cell State Modulation by Niche Covariation Analysis
一种高度活跃的细菌肌动蛋白驱动了另一种对螺旋体游泳运动能力至关重要的同工型的聚合。	Takahashi, D.	PDF	N/A	A highly active bacterial actin actuates the polymerization of another isoform essential for swimming motility of Spiroplasma
湿度作为昆虫系统昼夜节律同步的时间信号	Chen, S.-C.	PDF	N/A	Humidity as a zeitgeber for circadian entrainment of insect systems
通过药代动力学模型测量心脏中活体和离体状态下的细胞膜和线粒体膜电位	Waters, E. C.	PDF	N/A	Sarcolemmal and mitochondrial membrane potentials measured ex vivo and in vivo in the heart by pharmacokinetic modelling of sestamibi
兴奋性氨基酸转运蛋白3底物识别的结构基础	Qiu, B.	PDF	N/A	Structural basis of the excitatory amino acid transporter 3 substrate recognition
通过时间分辨小角X射线散射捕捉到的G-四链体折叠的早期事件	Monsen, R. C.	PDF	N/A	Early Events in G-quadruplex Folding Captured by Time-Resolved Small-Angle X-Ray Scattering
平衡运动脊髓回路中的兴奋与抑制	Chia, R.	PDF	N/A	Balancing Excitation and Inhibition in the Locomotor Spinal Circuits
糖萼生成膜曲率和感知膜曲率的生物物理建模	Xiao, K.	PDF	N/A	Biophysical modeling of membrane curvature generation and curvature sensing by the glycocalyx
从旋转平均的二维X射线衍射图样中恢复昆虫飞行肌的三维结构	Iwamoto, H.	PDF	N/A	Restoration of 3-D structure of insect flight muscle from a rotationally averaged 2-D X-ray diffraction pattern
膜辅助Aβ40聚集途径	Muhammedkutty, F. N. K.	PDF	N/A	Membrane-assisted Aβ40 aggregation pathways
使用多重生物传感器条形码校准基于FRET的生物传感器	Wu, J.-W.	PDF	N/A	Calibration of FRET-based biosensors using multiplexed biosensor barcoding
利用基于模拟的推理从一维细胞轨迹中估计细胞力学参数	Heyn, J.	PDF	N/A	Cell-mechanical parameter estimation from 1D cell trajectories using simulation-based inference
模拟鼻窦粘液清除：活性表面衬里的产液腔内的薄膜流动	Desai, N.	PDF	N/A	Modelling mucus clearance in sinuses: thin-film flow inside a fluid-producing cavity lined with an active surface
可再生活性物质中的分离、有限时间弹性奇异性和粗化现象	Roychowdhury, A.	PDF	N/A	Segregation, Finite Time Elastic Singularities and Coarsening in Renewable Active Matter
伴侣介导的异型相分离阻止朊蛋白病理性Y145Stop变体的淀粉样形成	Arora, L.	PDF	N/A	Chaperone-mediated heterotypic phase separation prevents the amyloid formation of the pathological Y145Stop variant of the prion protein
Aquavert：用于微生物垂直游泳的成像和微流体技术	Obenshain, H. B.	PDF	N/A	Aquavert: Imaging and Microfluidics for Vertical Swimming of Microorganisms
运动持续时间影响运动后血容量增多的程度，但不影响急性高强度间歇运动中促红细胞生成素的反应	Tripp, T. R.	PDF	N/A	Session duration affects the magnitude of post-exercise hypervolemia but not the erythropoietin response to acute high-intensity interval exercise
精确而非预测：身体所有权错觉作为贝叶斯推理下在线精确适应的结果	Novicky, F.	PDF	N/A	Precision not prediction: Body-ownership illusion as a consequence of online precision adaptation under Bayesian inference
下一代Cu(II)选择性肽穿梭体可防止Cu(Aβ)诱导的毒性和同种异型海马切片中的小胶质细胞活化	Okafor, M.	PDF	N/A	Next-generation Cu(II) selective peptide shuttles prevent Cu(Aβ)-induced toxicity and microglial activation in organotypic hippocampal slices
盲人足球运动员的楔前叶/后扣带皮层灰质体积增加	Morita, T.	PDF	N/A	Gray matter volume increase in the retrosplenial/posterior cingulate cortices of blind soccer players
孟加拉国感染志贺氏菌的幼儿中，O特异性多糖（OSP）特异性功能抗体反应有限	Bernshtein, B.	PDF	N/A	Limited O-specific polysaccharide (OSP)-specific functional antibody responses in young children with Shigella infection in Bangladesh
拓扑驱动法发现跨膜蛋白S-棕榈酰化	Forrester, M. T.	PDF	N/A	Topology-Driven Discovery of Transmembrane Protein S-Palmitoylation
中医药调节心脏微血管内皮细胞在多种损伤模型中的机制：一项全面的系统综述	Zhou, H.	PDF	N/A	Mechanisms of traditional Chinese medicine in modulating cardiac microvascular endothelial cells in various injury models: A comprehensive systematic review
GSK-3β的错误调控通过Shot和Tau导致轴突微管卷曲	Voelzmann, A.	PDF	N/A	Mis-regulation of GSK-3β causes axonal microtubule curling through Shot and Tau
损失还是重新分配？一种更好地估计由于人类活动增加而导致的动物分布和数量区域变化的途径	Mercker, M.	PDF	N/A	Loss or redistribution? A better way of estimating regional changes in animal distribution and numbers caused by increased human activities
推断蜜蜂遗传多样性的长期和短期决定因素：养蜂影响与保护策略	Leroy, T.	PDF	N/A	Inferring long-term and short-term determinants of genetic diversity in honey bees: Beekeeping impact and conservation strategies
东非和南非人群中高分辨率I类HLA-A、-B和-C的多样性	Ndhlovu, Z.	PDF	N/A	High Resolution Class I HLA -A, -B, and -C Diversity in Eastern and Southern African Populations
噬菌体L衣壳装饰蛋白的模板化三聚作用	Woodbury, B. M.	PDF	N/A	Templated trimerization of the phage L decoration protein on capsids
细菌毒素SsdA对单链DNA胞嘧啶脱氨作用的序列上下文无关的结构基础	Yin, L.	PDF	N/A	Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA
基于表面的与基于体素的有限元头部模型：应变响应的比较分析	Zhou, Z.	PDF	N/A	Surface-Based vs. Voxel-Based Finite Element Head Models: Comparative Analyses of Strain Responses
孔雀羽毛角蛋白的初步结构	Russ, P.	PDF	N/A	Feather keratin in Pavo cristatus: A tentative structure
细菌表面的直接接触会引发宿主吞噬体膜的相分离。	Bhausaheb, A. J.	PDF	N/A	Direct contact of the bacterial surface induces phase separation in the host phagosome membrane
内分泌干扰化学物质非单调剂量反应的潜在机制：系统负反馈调节的干扰	Shi, Z.	PDF	N/A	Interference with Systemic Negative Feedback Regulation as a Potential Mechanism for Nonmonotonic Dose-Responses of Endocrine-Disrupting Chemicals
用餐期间进行对话所花费的时间可以预测默认网络功能：来自被动移动感知和fMRI研究的证据。	Bhatt, D.	PDF	N/A	Time spent in conversation over meals predicts default network function: Evidence from a passive mobile-sensing and fMRI study.
信心评分数据的信心-噪声信心增强（CNCB）模型	Mamassian, P.	PDF	N/A	The Confidence-Noise Confidence-Boost (CNCB) model of confidence rating data
TGFβ使类似肺泡的巨噬细胞在TLR2激活后诱导I型干扰素	Thomas, S. M.	PDF	N/A	TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation
海滨沉积物中分离放线菌的次级代谢产物生物活性分析	Shubhro, K.	PDF	N/A	Bioactivity Analysis of Secondary Metabolites from Actinomycetes' Isolated from Coastal Sediments
呼吸上皮的三维纳米结构揭示了运动纤毛-根丝-线粒体之间的通信轴	Vijayakumaran, A.	PDF	N/A	3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication
Pcbp1 在多能性背景下限制 Oct4 的表达	Bakhmet, E. I.	PDF	N/A	Pcbp1 constrains Oct4 expression in the context of pluripotency
人类胰岛素受体外域的深度突变扫描，以指导胰岛素抵抗的精准治疗	Aslanzadeh, V.	PDF	N/A	Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance
单分子磁镊揭示了TAV2b衍生肽能够解旋并稳定双链RNA	Rashid, Z. M.	PDF	N/A	Single-molecule magnetic tweezers reveals that TAV2b-derived peptides underwind and stabilize double-stranded RNA
超分子酶-肽凝胶用于局部治疗性生物催化	Fuchs, M.	PDF	N/A	Supramolecular Enzyme-Peptide Gels for Localized Therapeutic Biocatalysis
AI驱动的耐碱性蛋白质进化及其在大规模生产中的应用	Kang, L.	PDF	N/A	AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production
基于同步加速器的质子和基于直线加速器电子的超高剂量率照射在急性胃肠道毒性方面存在不一致。	Liu, K.	PDF	N/A	Discordance in acute gastrointestinal toxicity between synchrotron-based proton and linac-based electron ultra-high dose rate irradiation
在PURE系统中从丙酮酸再生ATP	Yadav, S.	PDF	N/A	ATP Regeneration from Pyruvate in the PURE System
测试免疫计算模型——一项受邀挑战，旨在预测百日咳疫苗接种结果	Shinde, P.	PDF	N/A	Putting computational models of immunity to the test - an invited challenge to predict B. pertussis vaccination outcomes
邻近标记技术定义了小鼠和原代人巨噬细胞吞噬体腔的蛋白质组	Allsup, B. L.	PDF	N/A	Proximity labeling defines the phagosome lumen proteome of murine and primary human macrophages
一种1型免疫-基质细胞网络介导了疾病耐受性和肠道感染的屏障保护作用	Westfall, S.	PDF	N/A	A type 1 immune-stromal cell network mediates disease tolerance and barrier protection against intestinal infection
加拿大原住民传统疗法对伤口感染模拟条件下MRSA浮游和生物膜细菌的抗菌潜力	Rieger, C. D.	PDF	N/A	The antimicrobial potential of traditional remedies of Indigenous Peoples from Canada against MRSA planktonic and biofilm bacteria in wound-infection mimetic conditions
对美国犬钩虫感染相关风险因素及苯并咪唑F167Y抗药性标记多态性的研究	Jimenez Castro, P. D.	PDF	N/A	Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States
白纹夜蛾（鳞翅目：Hyles lineata）的性别特异性化学感觉基因表达表明气味结合蛋白在寄主植物选择中发挥作用	Godfrey, R. K.	PDF	N/A	Sex-specific chemosensory gene expression in the whitelined sphinx moth (Lepidoptera: Hyles lineata) suggests a role for odorant-binding proteins in host plant choice
通过CTCF结合活性的获得和丧失来鉴定有害的非编码变异	Tubbs, C.	PDF	N/A	Identifying deleterious noncoding variation through gain and loss of CTCF binding activity
增强子激活来自染色体外DNA中的转座元件	Kraft, K.	PDF	N/A	Enhancer activation from transposable elements in extrachromosomal DNA
通过线粒体酶复合物的计算基因组学推进骨髓增生异常综合征的变异表型分析	Dong, J.	PDF	N/A	Advancing Variant Phenotyping in Myelodysplastic Syndromes via Computational Genomics of Mitochondrial Enzyme Complexes
依赖二聚化的凝胶状dsDNA凝聚作用是人类cGAS激活的基础	Sohn, J.	PDF	N/A	Dimerization-dependent gel-like condensation with dsDNA underpins the activation of human cGAS
机器学习驱动的高精度细胞液滴生物打印优化	Shin, J.	PDF	N/A	Machine Learning Driven Optimization for High Precision Cellular Droplet Bioprinting
投影统计 ProST 在线统计评估数据投影分析中的组分离	Salem, D.	PDF	N/A	Projection Statistics ProST Online statistical assessment of group separation in data projection analysis
通过精确的细胞周期状态映射揭示的细胞身份将数据模式联系起来	Alahmari, S.	PDF	N/A	Cell identity revealed by precise cell cycle state mapping links data modalities
MYC 与 IIa 类 HDAC 抑制剂联合作用可增强非小细胞肺癌中的线粒体功能障碍	Park, J.	PDF	N/A	MYC plus class IIa HDAC inhibition potentiates mitochondrial dysfunction in non-small cell lung cancer
基于图曲率的免疫检查点响应生物标志物发现流程	Bannon, J. J.	PDF	N/A	A Graph Curvature-Based Pipeline for Discovering Immune Checkpoint Response Biomarkers
结合循环性发热与紫锥菊苷对胰腺癌细胞PANC-1产生协同治疗效果	Chen, W.-T.	PDF	N/A	Combination of cycling hyperthermia and Echinacoside creates synergistic curing effect on pancreatic cancer PANC-1 cells
小鼠动脉粥样硬化斑块中细胞的分子和时空特征	Hou, P.	PDF	N/A	Molecular and spatiotemporal characterization of cells in murine atherosclerotic plaques
额叶异常活动与唤醒水平和行动启动及反应力度相关	Klein, F.	PDF	N/A	Aberrant prefrontal activity and arousal level correlate with action initiation and response vigor
MIP3α-RelMtb鼻内DNA疫苗在小鼠和猕猴中诱导了反应性T细胞向肺部的浸润。	Gordy, J. T.	PDF	N/A	MIP3α-RelMtb intranasal DNA vaccination induces reactive T-cell infiltration into the lungs in mice and macaques
喜马拉雅长尾叶猴的群体遗传学及其分类学意义	M R, S.	PDF	N/A	Population genetics of Himalayan langurs and its taxonomic implications
全基因组鉴定稳定的RNA-染色质相互作用	Wen, X.	PDF	N/A	Genome-wide identification of stable RNA-chromatin interactions
人类增强子体内诱变敏感性图谱	Kosicki, M.	PDF	N/A	Mutagenesis Sensitivity Mapping of HumanEnhancers In Vivo
三碘甲状腺原氨酸和黄芩素的双重干预双向上调Klotho，减轻老年BALB/c小鼠慢性肾脏病及其并发症	Mohanty, S. K.	PDF	N/A	A Dual intervention of Triiodothyronine and Baicalein bi-directionally upregulates Klotho with attenuation of chronic kidney disease and its complications in aged BALB/c mice
使用多种机器学习框架对病毒逃逸语言模型进行系统评估	Allman, B.	PDF	N/A	A systematic evaluation of the language-of-viral-escape model using multiple machine learning frameworks
增强Vaxign-DL以预测疫苗候选者，加入ESM生成的特征	Chen, Y.	PDF	N/A	Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features
胎鼠在子宫内的脑脊液压力：外部因素对脑室空间施加压力	Tsujikawa, K.	PDF	N/A	CSF pressure in fetal mice in utero: External factors pressurize the intraventricular space
基于膜的芽殖酵母细胞器应激反应	Sheng, P.	PDF	N/A	Stress response of membrane-based cell organelles in budding yeast
解析斑马鱼早期胚胎发育过程中细胞特异性转录异质性和可变剪接	Lin, X.	PDF	N/A	Deciphering the Cell Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish
# BioRxiv 2024-09-07 Papers

标题	作者	PDF链接	代码仓库	Title
哺乳动物前脑中谷氨酸能突触的分子结构	Peukes, J.	PDF	N/A	The molecular infrastructure of glutamatergic synapses in the mammalian forebrain
基于物种独立性假设的随机群落模型中的Jaccard相异度	Iritani, R.	PDF	N/A	Jaccard dissimilarity in stochastic community models based on the species-independence assumption
婴儿的大脑中视觉类别表征何时出现？	Yan, X.	PDF	N/A	When Do Visual Category Representations Emerge in Infants' Brains?
用于分析光纤光度实验中试验级时间动态的统计框架	Loewinger, G.	PDF	N/A	A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments
物种共存边缘距离的分布	DESALLAIS, M.	PDF	N/A	The distribution of distances to the edge of species coexistence
资源可用性与亲本觅食策略对幼年麻雀个体特化作用的影响	Ricote, N.	PDF	N/A	The Interplay of Resource Availability and Parent Foraging Strategies on Juvenile Sparrow Individual Specialization
Pannexin 1 和 Pannexin 3 在皮肤鳞状细胞癌的肿瘤发生特性中发挥不同的调控作用。	O'Donnell, B. L.	PDF	N/A	Pannexin 1 and Pannexin 3 differentially regulate the tumorigenic properties of cutaneous squamous cell carcinoma
训练有素的跑步者中长距离跑步表现指标受先进跑鞋技术钉的影响	Rodrigo-Carranza, V.	PDF	N/A	Influence of advanced footwear technology spikes on middle- and long-distance running performance measures in trained runners
通过蛋白质结构扩散实现精确构象采样	Fan, J.	PDF	N/A	Accurate Conformation Sampling via Protein Structural Diffusion
莱姆病螺旋体伯氏疏螺旋体外表面蛋白C（OspC）的精细人源B细胞表位图谱	Freeman-Gallant, G.	PDF	N/A	A refined human linear B cell epitope map of Outer surface protein C (OspC) from the Lyme disease spirochete, Borreliella burgdorferi
脂质-siRNA偶联物进入血管周运输机制，并在中枢神经系统中实现广泛而持久的敲低效果。	Sorets, A.	PDF	N/A	Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system
量化为向量场的神经网络	Szeier, S.	PDF	N/A	Neuronal networks quantified as vector fields
鸟类白蛋白糖基化速率的变异表明其对相对高血糖的抵抗力，而非符合生命节奏综合征假说。	Moreno Borrallo, A.	PDF	N/A	Variation in albumin glycation rates in birds suggests resistance to relative hyperglycaemia rather than conformity to the pace of life syndrome hypothesis
有袋类动物的免疫保护机制受到抗菌肽cathelicidin增强子共享和基因簇重复的影响。	Park, J.	PDF	N/A	Marsupial immune protection is shaped by enhancer sharing and gene cluster duplication of cathelicidin antimicrobial peptides
组蛋白去甲基酶LSD1在隐球菌感染期间调节脂质稳态	Lohia, G. K.	PDF	N/A	Histone demethylase LSD1 regulates lipid homeostasis duringCryptococcus neoformans infection
食品污染物脱氧雪腐镰刀菌烯醇的低浓度可引发凋亡并损害促性腺激素释放激素诱导的垂体类促性腺细胞中黄体生成素分泌。	Cai, G.	PDF	N/A	Low concentrations of the food contaminant Deoxynivalenol trigger apoptosis and impair GnRH-induced LH secretion in pituitary gonadotrope-like cells
葡萄藤细胞对生理剂量乙醇的反应，其中包括诱导对热应激的抗性。	Diot, A.	PDF	N/A	Responses of grapevine cells to physiological doses of ethanol, among which induced resistance to heat stress
在不对称细胞分裂过程中，线粒体的非随机分离有助于子细胞命运的分化。	Segos, I.	PDF	N/A	Non-random segregation of mitochondria during asymmetric cell division contributes to cell fate divergence in daughter cells
巨噬细胞内在的MDA5-IRF5轴驱动HIV-1 icRNA诱导的炎症反应	Ramaswamy, S.	PDF	N/A	Macrophage-intrinsic MDA5-IRF5 axis drives HIV-1 icRNA-induced inflammatory responses
赖氨酸82的乙酰化通过破坏其核输入，启动TDP-43的核功能丧失。	Zhang, S.	PDF	N/A	Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import
几何推导的动作电位标记用于模型开发：一种有原则的方法？	Clerx, M.	PDF	N/A	Geometrically-derived action potential markers for model development: a principled approach?
依赖于压电效应（PIEZO）的微环境机械感应对于肠道干细胞命运决定和维持至关重要。	Baghdadi, M. B.	PDF	N/A	PIEZO-dependent mechano-sensing of the niche is essential for intestinal stem cell fate decision and maintenance
在表皮发育过程中，隔膜连接成分在信号通路调控和细胞极性方面具有独特的非封闭功能	Holtwick, V.	PDF	N/A	Distinct Non-occluding Functions of Septate Junction Components in Signaling Pathway Regulation and Cell Polarity During Epithelial Development
α-连环蛋白的磷酸化在有丝分裂期间升高，以抵抗顶端圆化和上皮屏障泄漏。	Le, P. M.	PDF	N/A	α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak
PI3K/AKT信号通路通过c-myc介导应激诱导的淀粉样蛋白聚集	Lacroix, E.	PDF	N/A	PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc
白色念珠菌中的五EF-手蛋白Pef1在膜扰动位点发挥作用，以支持极性生长和膜完整性。	Weichert, M.	PDF	N/A	The penta-EF-hand protein Pef1 of Candida albicans functions at sites of membrane perturbation to support polarized growth and membrane integrity
节点调制器（NOMO）是一种承载力的跨膜蛋白，对于肌肉分化是必需的。	Naughton, B.	PDF	N/A	Nodal Modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation
GDF11分泌细胞移植能有效改善与年龄相关的肺纤维化	Nagy, A.	PDF	N/A	GDF11 secreting cell transplant efficiently ameliorates age-related pulmonary fibrosis
Pax转录因子EGL-38将EGFR信号传导与秀丽隐杆线虫阴门中特定细胞类型的顶端细胞外基质的组装联系起来。	Schmidt, H. F.	PDF	N/A	The Pax transcription factor EGL-38 links EGFR signaling to assembly of a cell-type specific apical extracellular matrix in the Caenorhabditis elegans vulva
发育中的人类视网膜的睫状缘区在妊娠晚期之前一直维持着视网膜祖细胞。	Eldred, K. C.	PDF	N/A	Ciliary marginal zone of the developing human retina maintains retinal progenitor cells until late gestational stages
Wnt/β-连环蛋白信号传导支撑了肝片吸虫幼虫的生长和发育。	Armstrong, R.	PDF	N/A	Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development
RNA结合调控级联控制果蝇雄性生殖系干细胞谱系中从增殖到分化的转变	Harris, D. E.	PDF	N/A	An RNA binding regulatory cascade controls the switch from proliferation to differentiation in the Drosophila male germ line stem cell lineage
盐诱导激酶对牙槽骨发育、稳态及牙槽窝愈合的调控作用	Tokavanich, N.	PDF	N/A	Control of alveolar bone development, homeostasis, and socket healing by salt inducible kinases
一种简单的围产期哺乳动物卵巢免疫组织化学方法揭示了由DNA损伤和非联会引起的卵母细胞凋亡的不同动力学。	Kogo, H.	PDF	N/A	A simple immunohistochemical method for perinatal mammalian ovaries revealed different kinetics of oocyte apoptosis caused by DNA damage and asynapsis.
胰岛初级纤毛中轴丝动力蛋白的扩展显微镜观察	Dong, X.	PDF	N/A	Expansion microscopy of axonemal dyneins in islet primary cilia
单细胞转录组分析揭示CD34作为人类窦房结起搏细胞的新型标志物	Lim, A. A.	PDF	N/A	Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes
钙蛋白酶在膜修复过程中调控含有膜联蛋白的微囊泡的分泌	Williams, J. K.	PDF	N/A	Calpains Orchestrate Secretion of Annexin-containing Microvesicles during Membrane Repair
果蝇肌生成抑制因子Him基因对于成年肌肉功能和肌肉干细胞的维持至关重要。	Mitchell-Gee, R.	PDF	N/A	The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance
刺胞动物胚胎中的平面细胞极性协调为动物体轴的进化提供了线索。	Uveira, J.	PDF	N/A	Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution
中等剂量砷暴露会损害小鼠肾单位的形成	Alonso, C. A. I.	PDF	N/A	Mouse nephron formation is impaired by moderate-dose arsenical exposure
计算机靶点识别揭示IL12B为小分子药物开发的候选靶点	Tanner, T. J.	PDF	N/A	In Silico Target Identification Reveals IL12B as a Candidate for Small Molecule Drug Development
腺样囊性癌中HLA I类分子的可逆性下调	Li, A.	PDF	N/A	Reversible Downregulation of HLA Class I in Adenoid Cystic Carcinoma
利用作物模型引导的机器学习方法，从数据稀疏的田间试验中估算土壤矿质氮	Gupta, R.	PDF	N/A	Estimating soil mineral nitrogen from data-sparse field experiments using crop model-guided machine learning approach
在莱茵衣藻中敲除羧基转移酶互作蛋白1（CTI1）使其油脂含量提高了五倍，同时不影响细胞生长。	Li, Z.	PDF	N/A	Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth
远程缺血预处理通过CD36介导的吞噬作用减轻跨神经元退化并促进中风恢复。	Ju, H.	PDF	N/A	Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis.
寡聚原花青素对中性粒细胞胞外陷阱的抑制作用通过肠-肾轴减轻化疗诱导的慢性肾损伤	Luan, Y.	PDF	N/A	Inhibition on neutrophil extracellular traps by oligomeric procyanidins alleviate chemotherapy-induced chronic kidney injury via gut-kidney axis
高效多重非病毒工程化及扩增多克隆γδ CAR-T细胞用于免疫治疗	Bridge, J.	PDF	N/A	Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy
副粘病毒基质蛋白通过与细胞质中的外显子连接复合体相互作用，调节宿主细胞的翻译过程。	Hung, C.-T.	PDF	N/A	Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm
澳大利亚犬钩虫（Ancylostoma caninum）中广泛存在苯并咪唑抗性单核苷酸多态性（SNPs）	Abdullah, S.	PDF	N/A	Widespread occurrence of benzimidazole resistance SNPs in the canine hookworm, Ancylostoma caninum, in Australia
数据发布：使用FIB-SEM和机器学习对P7小鼠组织微观结构进行高分辨率成像和分割	Ackerman, D.	PDF	N/A	Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning
基因型和年龄对无菌SCID猪仔体内特定微生物群的影响	Widmer, K. M.	PDF	N/A	Effect of Genotype and Age on a Defined Microbiota in Gnotobiotic SCID Piglets
鬣蜥属（Chamaeleo calyptratus，又称面纱变色龙）染色体规模的基因组组装和注释为爬行动物的进化和发育机制提供了深入见解。	Shylo, N.	PDF	N/A	Chamaeleo calyptratus (veiled chameleon) chromosome-scale genome assembly and annotation provides insights into the evolution of reptiles and developmental mechanisms.
老年小鼠表现出更快的静脉注射阿片类药物自我给药获取速度，但对摄入量的影响不一。	Sharpe, A. L.	PDF	N/A	Aged mice exhibit faster acquisition of intravenous opioid self-administration with variable effects on intake
为体外膜氧化治疗期间的医疗设备进行计算机模拟临床试验生成虚拟患者数据	Landoll, M.	PDF	N/A	Generating virtual patient data for in-silico clinical trials of medical devices during extracorporeal membrane oxygenationtreatment
全原子连续恒定pH分子动力学中的力场限制	Peeples, C.	PDF	N/A	Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics
人诱导多能干细胞衍生的心肌细胞的激发计算研究	Shetty, R.	PDF	N/A	Computational Study of the Excitation of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes
T1D患者和进展者的性别特异性细胞因子、趋化因子和生长因子特征	Girdhar, K.	PDF	N/A	Sex-Specific Cytokine, Chemokine, and Growth Factor Signatures in T1D Patients and Progressors
城市化的生态和进化影响：应用因果建模框架	Borden, J. B.	PDF	N/A	Ecological and evolutionary impacts of urbanization: applying a causal modeling framework
CD4+Foxp3E2+调节性T细胞频率可预测乳腺癌的预后和复发。	Fusco, C.	PDF	N/A	CD4+Foxp3E2+ regulatory T cell frequency predicts breast cancer prognosis and recurrence
在乳头状病毒感染后两周，侵袭性癌症和自发性消退	Bilger, A.	PDF	N/A	Invasive cancer and spontaneous regression two weeks after papillomavirus infection
探索辣椒素对胃癌细胞基因表达及化疗增敏作用的影响	Meng, W.	PDF	N/A	Exploring the effect of capsaicin on gene expression and chemotherapy sensitization in gastric cancer cells
特定于脑桥的轴突微环境支持新发的胶质瘤生成	Xie, Z.	PDF	N/A	A pontine-specific axonal niche supports de novo gliomagenesis
铁死亡与细胞凋亡的相互作用及其通过BH3模拟物的调节	Qiu, Y.	PDF	N/A	Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics
Claudin-4 对细胞核-细胞周期交叉对话的重塑维持了卵巢肿瘤基因组的稳定性，并推动了对诱导基因组不稳定性药物的抗性。	Bitler, B. G.	PDF	N/A	Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents.
肾母细胞瘤中亚型特异性的进化模式及与临床相关的基因组不稳定性	Cresswell, G. D.	PDF	N/A	Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour
温度敏感的谷氨酸门控AMPA亚型iGluRs	Kumar Mondal, A.	PDF	N/A	Temperature Sensitive Glutamate Gating of AMPA-subtype iGluRs
将细菌素合成多重化以杀灭和预防抗菌药物耐药性	Quintero-Yanes, A.	PDF	N/A	Multiplexing bacteriocin synthesis to kill and prevent antimicrobial resistance
C7取代的喹啉作为鲍曼不动杆菌中AdeG外排泵的有效抑制剂	Zhu, Y.	PDF	N/A	C7-substituted Quinolines as Potent Inhibitors of AdeG Efflux Pumps in Acinetobacter baumannii
人转铁蛋白和乳铁蛋白协同支持脑膜炎奈瑟菌在小鼠鼻咽部的定殖	Lee, I. S.	PDF	N/A	Human transferrin and lactoferrin cooperatively support Neisseria meningitidis colonization in the murine nasopharynx
优化数字PCR检测方法以实现地表水中多重微生物来源追踪	Ghosh, S.	PDF	N/A	Optimizing Digital PCR Assays for Multiplexed Microbial Source Tracking in Surface Waters
社区范围内的相互作用维持了地热泉生境中的生命	Stephens, T. G.	PDF	N/A	Community-wide interactions sustain life in geothermal spring habitats
工程改造亚洲象TP53：TP53逆转录基因敲除激活了常见且独特的与癌症相关的通路	Karpinski, E.	PDF	N/A	Engineering Asian elephant TP53: TP53 retrogene knockouts activate common and unique cancer-relevant pathways
使用CycloneSEQ高效构建完整基因组以填补细菌草图组装中的空缺	Liang, H.	PDF	N/A	Efficiently Constructing Complete Genomes with CycloneSEQ to Fill Gaps in Bacterial Draft Assemblies
来自Thermotoga naphthophila的GH10家族热稳定木聚糖酶的3D建模：重组木聚糖酶的特性研究	Waris, A.	PDF	N/A	3D modeling of thermostable xylanase from Thermotoga naphthophila a member of GH10 family: characterization studies of recombinant xylanase
Vps4底物结合及其耦合机制：Vps4p底物招募与从自抑制中释放	Wienkers, H.	PDF	N/A	Vps4 substrate binding and coupled mechanisms of Vps4p substrate recruitment and release from autoinhibition
H/ACA snoRNP在加入核心90S前体核糖体之前，引导核糖体RNA亚域在卫星颗粒中进行折叠。	Fischer, P.	PDF	N/A	H/ACA snoRNP guides ribosomal RNA subdomain folding in a satellite particle before joining the core 90S pre-ribosome
人类DNA复制起始位点通过5-甲基脱氧胞苷的氧化作用在表观遗传学上被指定。	Krude, T.	PDF	N/A	Human DNA replication initiation sites are specified epigenetically by oxidation of 5-methyl-deoxycytidine
抑制特定Zn2+依赖性DUB活性及炎症的分子胶	Chandler, F.	PDF	N/A	Molecular glues that inhibit specific Zn2+-dependent DUB activity and inflammation
通过部分酶解植物细胞壁实现活体植物蛋白质的直接核递送	Gu, Q.	PDF	N/A	Direct Nuclear Delivery of Proteins on Living Plant via Partial Enzymatic Cell Wall Digestion
选择性激动肝脏和肠道FXR可预防肠外喂养新生猪的胆汁淤积和肠道萎缩	Jiang, Y.	PDF	N/A	Selective Agonism of Liver and Gut FXR Prevents Cholestasis and Intestinal Atrophy in Parenterally Fed Neonatal Pigs
不同吸湿性肥料颗粒的离散元模型构建及施肥排放验证	Chen, X. F.	PDF	N/A	Construction of Discrete Element Model of Different Moisture Hygroscopic Fertilizer Particles and Fertilizer Discharging Verification
高粱通过根系分泌物进行的邻近感知影响植物生理和生产力	Ben-Zeev, S.	PDF	N/A	Neighbor sensing through rhizodeposits in sorghum affects plant physiology and productivity
哺乳动物类胚胎发育的蛋白质组图谱及时间动态变化	Garge, R. K.	PDF	N/A	The proteomic landscape and temporal dynamics of mammalian gastruloid development
AxonFinder：肿瘤侵袭神经纤维的自动分割	Ait-Ahmad, K.	PDF	N/A	AxonFinder: Automated segmentation of tumor innervating neuronal fibers
大型齿鲸种内体型变异的总结	McClure, J.	PDF	N/A	A summary of intraspecific size variation for large odontocetes
羊角中CASP14基因的组织特异性及功能位点分析	Lu, X.	PDF	N/A	Tissue-specific and functional loci analysis of CASP14 gene in the sheep horn
离开补丁的决定和与学生相关的唤醒系统	Marzecova, A.	PDF	N/A	Patch-leaving decisions and pupil-linked arousal systems
英国版爱荷华辅音感知测试	Guo, X.	PDF	N/A	British Version of the Iowa Test of Consonant Perception
星形胶质细胞对EcoHIV感染小鼠可卡因运动性敏感化的调控	Xie, Q.	PDF	N/A	Astrocytic Regulation of Cocaine Locomotor Sensitization in EcoHIV Infected Mice
酒精饮用、焦虑及BNST神经元兴奋性的CRF神经元中食欲素受体信号传导的性别特异性作用	Ma, Y.	PDF	N/A	Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability
历史驱动的干扰抑制和目标增强的空间参考框架	Ilksoy, Y.	PDF	N/A	The spatial reference frame of history-driven distractor suppression and target enhancement
肌球蛋白XVA异构体参与了听觉毛细胞中依赖于机械转导的肌动蛋白细胞骨架重塑过程。	Lopez-Porras, A. I.	PDF	N/A	Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia
通过模拟肿瘤微环境的共培养实验鉴定增强NK细胞肿瘤杀伤活性的小分子	Binici, A.	PDF	N/A	Identification of small molecule enhancers of NK cell tumoricidal activity via a tumor microenvironment-mimicking co-culture assay
针对结核分枝杆菌持久菌的DNA疫苗可缩短治愈结核病所需的治疗时间。	Karanika, S.	PDF	N/A	Therapeutic DNA Vaccine Targeting Mycobacterium tuberculosis Persisters Shortens Curative Tuberculosis Treatment
线粒体超活性和活性氧驱动对黄热病病毒-17D减毒活疫苗的先天免疫	Muccilli, S. G.	PDF	N/A	Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine
来自海洋缺氧区的蓝细菌同时编码I型和II型核酮糖-1,5-二磷酸羧化酶/加氧酶（Rubisco）。	Jaffe, A. L.	PDF	N/A	Cyanobacteria from marine oxygen deficient zones encode both form I and form II rubiscos
多菌株噬菌体诱导的细菌感染清除	Marchi, J.	PDF	N/A	Multi-strain phage induced clearance of bacterial infections
T型电压门控钙通道CaV3.1作为多杀性巴氏杆菌毒素的候选受体，并参与了该毒素引起的呼吸上皮屏障破坏。	Bi, H.	PDF	N/A	The T-type voltage-gated Ca2+ channel CaV3.1 as a candidate receptor for Pasteurella multocida toxin and contributes to the disruption of respiratory epithelial barrier induced by the toxin
合理选择TbpB变体阐明了针对淋病奈瑟菌的广谱覆盖双价疫苗配方	Fegan, J. E.	PDF	N/A	Rational selection of TbpB variants elucidates a bivalent vaccine formulation with broad spectrum coverage against Neisseria gonorrhoeae
磷酸戊糖途径保护大肠杆菌免受抗生素致死性影响	Seregina, T.	PDF	N/A	Pentose Phosphate Pathway Protects E. coli from Antibiotic Lethality
通过小标签人工细菌E3连接酶进行蛋白质降解	Warming, S.	PDF	N/A	Protein degradation by small tag artificial bacterial E3 ligase
欧洲森林虫害爆发概率：基于六种森林昆虫特征校准的通用模型	COLLOT, D.	PDF	N/A	Probability of outbreaks of forest insects in Europe: a generic model calibrated on six forest insect profiles
地中海中的海蜇（Rhopilema nomadica）：分子证据支持其迁移，并提出关于其扩散的生态假说	Kuplik, Z.	PDF	N/A	Rhopilema nomadica in the Mediterranean: molecular evidence for migration and ecological hypothesis regarding its proliferation
重组塑造了wtf减数分裂驱动因子的多样化	Wang, Y.	PDF	N/A	Recombination shapes the diversification of the wtf meiotic drivers
探索新天地：印度谷子苋的成功适应与基因组完整性	Singh, A.	PDF	N/A	Going New Places: Successful Adaptation and Genomic Integrity of Grain Amaranth in India
雾化及静脉注射酶替代疗法对黏多糖贮积症II型小鼠的治疗效果	Shamoun, A. J.	PDF	N/A	Nebulized and intravenous enzyme replacement therapy in mice with mucopolysaccharidosis type II
通过HiCapR技术映射HIV-1 RNA结构、同源二聚体、长程相互作用及持久性结构域	Zhang, Y.	PDF	N/A	Mapping HIV-1 RNA Structure, Homodimers, Long-Range Interactions and persistent domains by HiCapR
在鼠属中，TCRα和TCRβ位点的独特进化	Peters, M. A.	PDF	N/A	Distinct evolution at TCRα and TCRβ loci in the genus Mus
在Lachenalia植物中发现的新型Phenuivirus种揭示了5'和3' RNA序列基序之间可能的共同进化	Dekker, R. J.	PDF	N/A	Discovery of a new Phenuivirus species in Lachenalia plants reveals possible co-evolution between 5' and 3' RNA sequence motifs
早期生活中肠道移动组的动态变化及决定因素	Fernandez-Pato, A.	PDF	N/A	Dynamics and determinants of the gut mobilome in early life
一种新型机制：胞内铁载体结合的铁离子被线粒体摄取，并在其内部还原为亚铁离子	Dutta, A.	PDF	N/A	A novel mechanism for the uptake of enterobactin-chelated ferric ions by the mitochondria and subsequent reduction to ferrous ions inside
结构蛋白质组学揭示了孕酮受体的顺序启动机制	Mann, M. D.	PDF	N/A	Structural proteomics defines a sequential priming mechanism for the progesterone receptor
呼吸复合物I中喹啉阴离子的催化相关性在生物能量转换中的作用	Zdorevskyi, O.	PDF	N/A	Catalytic relevance of quinol anion in biological energy conversion by respiratory complex I
RepeatParam：重复蛋白质参数化算法及重复蛋白质结构分析	Pretorius, D.	PDF	N/A	RepeatParam: Algorithm for Parameterising Repeat Proteins and Analysis of Repeat Protein Architectures
sTREM2的柔性茎域调节其与大脑中磷脂的相互作用	Saeb, D.	PDF	N/A	The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain
优化合成血管移植物力学行为的计算框架	Jiang, D.	PDF	N/A	A Computational Framework to Optimize the Mechanical Behavior of Synthetic Vascular Grafts
乙酸和优化硝酸盐水平对Chlorella Sorokiniana混合营养生长及蛋白质动态的影响	Chen, S.	PDF	N/A	Impact of Acetate and Optimized Nitrate Levels on Mixotrophic Growth and Protein Dynamics in Chlorella Sorokiniana
使用多维逆运动学与平均分段形态学评估临床评估中的关节角度数据。	Taitano, R. I.	PDF	N/A	Evaluating Joint Angle Data for Clinical Assessment Using Multidimensional Inverse Kinematics with Average Segment Morphometry.
非侵入性细胞膜电位测量的建模：LTSpice仿真与机器学习分析	Ma, X.	PDF	N/A	Modeling of Non-invasive Cell Membrane Potential Measurement: LTSpice Simulation and Machine Learning Analysis
通过整合小角散射与AlphaFold解析膜蛋白的构象集合	Lidbrink, S. E.	PDF	N/A	Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold
表达、纯化及表征大肠杆菌中的二酰化Lipo-YcjN	Trevino, M. A.	PDF	N/A	Expression, purification, and characterization of diacylated Lipo-YcjN from Escherichia coli
协调端粒脱氧核苷酸转移酶dUTP缺口末端标记（TUNEL）与多重迭代免疫荧光技术，能够丰富细胞死亡的空间背景信息。	Sherman, M. S.	PDF	N/A	Harmonizing terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) with multiplexed iterative immunofluorescence enriches spatial contextualization of cell death
根际细菌能促进防御和营养反应的激活，从而抑制大麦上的蚜虫种群。	Mbaluto, C.	PDF	N/A	Rhizobacteria prime the activation of defence and nutritional responses to suppress aphid populations on barley
使用综合多组学方法识别的产科综合征之间的胎盘网络差异	Piekos, S. N.	PDF	N/A	Placental Network Differences Among Obstetric Syndromes Identified With An Integrated Multiomics Approach
通过数学模型理解药物诱导的耐药性	Sontag, E. D.	PDF	N/A	Understanding therapeutic tolerance through a mathematical model of drug-induced resistance
一种可推广的脑形态异常检测规范深度自编码器：应用于双相情感障碍多站点StratiBip数据集的外部验证框架。	Sampaio, I. W.	PDF	N/A	A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.
识别分子梯度塑造视觉运动转换的突触特异性	Dombrovski, M.	PDF	N/A	Gradients of Recognition Molecules Shape Synaptic Specificity of a Visuomotor Transformation
多发性硬化症中克隆扩增的CD8+ T细胞的抗原特异性	Mittl, K.	PDF	N/A	Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis
基于病毒样颗粒的疫苗，针对按蚊唾液蛋白TRIO	Francian, A.	PDF	N/A	Virus-like particle-based vaccines targeting the Anopheles mosquito salivary protein, TRIO
异种花粉转移如何影响两种密切相关植物物种的协同进化和共存？	Morita, K.	PDF	N/A	How can interspecific pollen transfer affect the coevolution and coexistence of two closely related plant species?
在白面卷尾猴（Cebus imitator）中，MHC异质性可能提高从属雄性而非阿尔法雄性的生育成功率。	Buckner, J. C.	PDF	N/A	MHC heterozygosity may increase subordinate but not alpha male siring success in white-faced capuchin monkeys (Cebus imitator)
端粒到端粒的非洲野生稻（Oryza longistaminata）参考基因组揭示了片段和结构变异	Guang, X.	PDF	N/A	Telomere-to-telomere African wild rice (Oryza longistaminata) reference genome reveals segmental and structural variation
人类和蝙蝠基因组在COSMIC突变特征下的稳健性	Song, J.-H.	PDF	N/A	Human and bats genome robustness under COSMIC mutational signatures
信息论：评估基因组人工智能的框架	Robson, E. S.	PDF	N/A	Enformation Theory: A Framework for Evaluating Genomic AI
活体哺乳动物大脑的光学透明化	Talei Franzesi, G.	PDF	N/A	In Vivo Optical Clearing of Mammalian Brain
Metapipeline-DNA：一个全面的种系与体细胞基因组学Nextflow管道	Patel, Y.	PDF	N/A	Metapipeline-DNA: A Comprehensive Germline & Somatic Genomics Nextflow Pipeline
蛋白质设计档案（PDA）：40年蛋白质设计的洞见	Chronowska, M.	PDF	N/A	The Protein Design Archive (PDA): insights from 40 years of protein design
利用深度学习预测非编码突变对单细胞DNA甲基化的影响	Liu, Z.	PDF	N/A	Predicting the effect of non-coding mutations on single-cell DNA methylation using deep learning
DDGemb：利用嵌入和深度学习预测蛋白质在单点和多点变异下的稳定性变化	Savojardo, C.	PDF	N/A	DDGemb: predicting protein stability change upon single- and multi-point variations with embeddings and deep learning
建模如何由片状伪足驱动的细胞维持持续迁移并与外部障碍物相互作用	Sadhukhan, S.	PDF	N/A	Modelling how lamellipodia-driven cells maintain persistent migration and interact with external barriers
通过高分辨率原子力显微镜进行动质体DNA的多尺度拓扑分析	Diggines, B.	PDF	N/A	Multiscale topological analysis of kinetoplast DNA via high-resolution AFM
蛋白质亚基中的可切换构象：揭示二十面体病毒的组装动力学	Li, S.	PDF	N/A	Switchable Conformation in Protein Subunits: Unveiling Assembly Dynamics of Icosahedral Viruses
一种介导免疫摧毁衰老癌细胞的抗生素	Casagrande Raffi, G.	PDF	N/A	An antibiotic that mediates immune destruction of senescent cancer cells
基于代理与连续模型在细胞种群建模中的等价性。应用于微流控装置中胶质母细胞瘤的演化	Arroyo-Vazquez, R. B.	PDF	N/A	On the equivalence between Agent-Based and Continuum models for cell population modeling. Application to glioblastoma evolution in microfluidic devices
泊洛沙姆188在肌营养不良性心肌病中的差异有效性揭示了复杂的病理生理机制。	Heitzman, J.	PDF	N/A	Differential Effectiveness of Poloxamer 188 in Dystrophic Cardiomyopathy Reveals Complex Pathophysiology.
拟南芥RS2Z32和RS2Z33蛋白是动态剪接因子，其RNA识别基序（RRM）域有助于蛋白质-蛋白质和蛋白质-RNA相互作用。	Fanara, S.	PDF	N/A	The Arabidopsis RS2Z32 and RS2Z33 proteins are dynamic splicing factors whose RNA recognition motif (RRM) domain contributes to protein-protein and protein-RNA interactions
心律失常的神经表征：预测编码视角	Reinfeld, P.	PDF	N/A	Neural Representations of Extrasystoles: A Predictive Coding Perspective
机械渗透信号控制着多能干细胞中的染色质状态和命运转变	McCreery, K. P.	PDF	N/A	Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells
通过田间试验欧洲网络的元分析，在春二棱大麦中发现了新的位点和候选基因	Montardit-Tarda, F.	PDF	N/A	New loci and candidate genes in spring two-rowed barley detected through meta-analysis of a field trial European network
阿米巴虫属（Amoebophrya sp.）源自卡洛迪尼姆藻（Karlodinium veneficum）的核与线粒体基因组	DeMontigny, W.	PDF	N/A	The Nuclear and Mitochondrial Genomes of Amoebophrya sp. ex Karlodinium veneficum
Grb2磷酸化通过干扰凝聚物的组装，拮抗EGFR驱动的Ras激活。	Phan, H. T.	PDF	N/A	Grb2 Phosphorylation Antagonizes EGFR-driven Ras Activation by Interfering with Condensate Assembly
# BioRxiv 2024-09-05 Papers

标题	作者	PDF链接	代码仓库	Title
ESCRT蛋白CHMP5通过调控内溶酶体-线粒体介导的细胞衰老来限制骨形成。	Zhang, F.	PDF	N/A	The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence
个性化神经影像揭示了儿童兴趣对大脑语言处理的影响	Olson, H. A.	PDF	N/A	Personalized Neuroimaging Reveals the Impact of Children's Interests on Language Processing in the Brain
免疫细胞利用间歇性的整合素介导的牵引力进行三维迁移	Czerwinski, T.	PDF	N/A	Immune cells employ intermittent integrin-mediated traction forces for 3D migration
癌症相关成纤维细胞亚型调节肿瘤免疫微环境，并与皮肤癌恶性程度相关。	Forsthuber, A.	PDF	N/A	Cancer associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy
三维变量分析揭示了人类天冬酰胺合成酶中控制氨传输的隐藏构象动力学	Coricello, A.	PDF	N/A	3D Variable Analysis Reveal a Hidden Conformational Dynamics Controlling Ammonia Transport in Human Asparagine Synthetase
人类工作记忆和长时记忆中的注意力集中：通过可分离过程带来的益处	Gong, D.	PDF	N/A	Focusing attention in human working memory and long-term memory: benefits through dissociable processes
健康成人中人诺如病毒的宿内和宿间进化	Ramani, S.	PDF	N/A	Intra- and Inter-host Evolution of Human Norovirus in Healthy Adults
昆虫变化：评论	Gaume, L.	PDF	N/A	InsectChange: Comment
自噬限制了真菌在拟南芥根部中的定植	Zecua-Ramirez, P.	PDF	N/A	Autophagy restricts fungal accommodation in the roots of Arabidopsis thaliana
通过亲和捕获的淋巴细胞冷冻电子断层扫描揭示的胞外纤维	Engel, L.	PDF	N/A	Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes
利用全细胞模型和机器学习加速设计尺寸减小的埃希氏大肠杆菌基因组	Gherman, I. M.	PDF	N/A	Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning
利用适应度景观建模和强化学习加速蛋白质工程	Sun, H.	PDF	N/A	Accelerating protein engineering with fitness landscape modeling and reinforcement learning
一种“自杀性”BCG菌株在猕猴中提供了增强的免疫原性和对结核分枝杆菌的强大保护。	Smith, A. A.	PDF	N/A	A "suicide" BCG strain provides enhanced immunogenicity and robust protection against Mycobacterium tuberculosis in macaques
生物传感器表征：从蛋白质组分角度出发的正式方法	Arias Vaccari, N.	PDF	N/A	Biosensors Characterization: Formal methods from the Perspective of Proteome Fractions
免疫相关蛋白Serpina3n对大脑发育和髓鞘形成的可调控作用	Zhu, M.	PDF	N/A	Dispensable regulation of brain development and myelination by the immune-related protein Serpina3n
与惊讶的沟通——新奇人类互动中目标信号的计算原理	Buidze, T.	PDF	N/A	Communication with Surprise-Computational Principles of Goal Signaling in Novel Human Interactions
一线抗结核药物应激下耻垢分枝杆菌的遗传稳定性：评估其诱变潜能	Molnar, D.	PDF	N/A	Genetic Stability of Mycobacterium smegmatis under the Stress of First-Line Antitubercular Agents: Assessing Mutagenic Potential
小鼠犁鼻器在单细胞分辨率下的分子、细胞和发育组织	Hills, M. H.	PDF	N/A	Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution
单细胞MALDI-MSI分析复制性衰老成纤维细胞模型中的脂质和蛋白质	Sekera, E. R.	PDF	N/A	Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model
早期生活压力诱导的miR-708-5p调控小鼠情绪障碍相关的行为表型，并可能是双相情感障碍的潜在诊断生物标志物。	Gilardi, C.	PDF	N/A	Early life stress-induced miR-708-5p regulates mood disorder-associated behavioural phenotypes in mice and is a potential diagnostic biomarker for bipolar disorder
使用AlphaFold预测PROTAC介导的蛋白质-蛋白质界面的挑战	Pereira, G. P.	PDF	N/A	Challenges in predicting PROTAC-mediated Protein-Protein Interfaces with AlphaFold
成年小鼠中天然前体的动态追踪	Liu, S.	PDF	N/A	Dynamic Tracking of Native Precursors in Adult Mice
细胞周期依赖性的P-bodies中mRNA定位	SAFIEDDINE, A.	PDF	N/A	Cell cycle-dependent mRNA localization in P-bodies
PIKFYVE抑制通过氨积累导致源自内体和溶酶体的空泡扩大	Uwada, J.	PDF	N/A	PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulation
生态而非社会因素解释了头足类动物的大脑尺寸：我们需要一个新的模型来解释大脑进化的过程	Basava, K.	PDF	N/A	Ecological not social factors explain brain size in cephalopods: we need a new model for the evolution of big brains
在化学定义的合成饮食中，纯化的纤维会破坏杂食性昆虫模型的肠道微生物群。	Dockman, R.	PDF	N/A	Purified fibers in chemically defined synthetic diets destabilize the gut microbiome of an omnivorous insect model
脂多糖出口的动态基础由LptB2FGC提供	Dajka, M.	PDF	N/A	Dynamic basis of lipopolysaccharide export by LptB2FGC
对Physcomitrella N端组学的快照揭示了细胞器蛋白质的N端甲基化	Hoernstein, S. N. W.	PDF	N/A	A snapshot of the Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins
工程化酿酒酵母以生产富含石榴酸的酵母生物质	Wang, J.	PDF	N/A	Engineering Saccharomyces cerevisiae for the production of punicic acid-rich yeast biomass
通过泛线粒体基因组图谱揭示的真菌植物病原体中的频繁基因交换	van Westerhoven, A.	PDF	N/A	Frequent genetic exchanges revealed by a pan-mitogenome graph of a fungal plant pathogen
1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）处理的成年斑马鱼作为帕金森病模型	Bagwell, E.	PDF	N/A	1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Treated Adult Zebrafish as a Model for Parkinsons Disease
由PIM1激活的HIF-1组装了一个病理性的转录复合物和调控网络，驱动JAK2V617F骨髓增生性肿瘤疾病的发展。	Kealy, D.	PDF	N/A	HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease
长读RNA测序揭示了等位基因特异性的N6-甲基腺苷修饰	Park, D.	PDF	N/A	Long-read RNA sequencing reveals allele-specific N6-methyladenosine modifications
多模态MEG与微结构MRI研究人类海马场景网络	Read, M.-L.	PDF	N/A	Multimodal MEG and microstructure-MRI investigations of the human hippocampal scene network
P(all-atom)正在为蛋白质设计开辟新的道路	Qu, W.	PDF	N/A	P(all-atom) Is Unlocking New Path For Protein Design
优化基于转录组的合成致死预测，以提高早期乳腺癌的精准肿瘤学：BC-SELECT	Kim, Y.	PDF	N/A	Optimizing transcriptome-based synthetic lethality predictions to improve precision oncology in early-stage breast cancer: BC-SELECT
RBN-2397是一种PARP7抑制剂，与紫杉醇联合使用可协同抑制卵巢癌细胞的增殖和迁移。	Spirtos, A. N.	PDF	N/A	RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells
晶体学中的自动晶体识别：直接方法与人工智能策略的比较	Lages, C. F.	PDF	N/A	Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies
慢性间歇性饮酒会导致皮质-纹状体-边缘系统振荡出现性别特异性的紊乱。	Hewitt, K.	PDF	N/A	Chronic intermittent alcohol yields sex-specific disruptions in cortical-striatal-limbic oscillations
GPRC6A作为一种新型鲜味受体，通过鸟氨酸增强了味觉偏好	Yamamoto, T.	PDF	N/A	GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine
在垒球运动中，经过针对性的感知认知训练后，击球技能多年持续提升	Muraskin, J.	PDF	N/A	Multiyear Improvement In Batting Skills Following Targeted Perceptual Cognitive Training In Softball
质膜转运蛋白渐进性僵硬蛋白同源物（ANKH/Ankh）介导衰老相关的细胞外柠檬酸盐，并受DNA损伤、炎症和衰老的调控。	James, E. N.	PDF	N/A	Plasma membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ankh) mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing
斑马鱼幼体数量感知的神经基础	Luu, P.	PDF	N/A	Neural Basis of Number Sense in Larval Zebrafish
疟蚊复杂的群聚动力学源于简单且最小化的互动行为规则。	Cribellier, A.	PDF	N/A	The complex swarming dynamics of malaria mosquitoes emerges from simple minimally-interactive behavioral rules
实验室观察显示，成年大黄蜂幼虫在夜间仍会继续发出叫声。	FUJIOKA, H.	PDF	N/A	Laboratory observations reveal that mature Vespa mandarinia larvae continue calling at night
在老鼠视觉皮层中，视觉体验依赖的听觉和视觉可塑性	Terra, H.	PDF	N/A	Visual experience-dependent auditory and visual plasticity in the mouse visual cortex
全脑电路在自闭症斑马鱼模型中改变听觉习惯化的作用。	Wilde, M.	PDF	N/A	Brain-wide circuitry underlying altered auditory habituation in zebrafish models of autism.
海马神经突起发育变化与调节低θ振荡相关基因的表达共定位	Kember, J.	PDF	N/A	Developmental changes in hippocampal neurite colocalize with the expression of genes involved in modulating low-theta oscillations
右侧尾状核体积与注意缺陷/多动障碍（ADHD）儿童的执行功能	Hai, T.	PDF	N/A	Right Caudate Volume and Executive Functions in Children with Attention-Deficit/Hyperactivity Disorder (ADHD)
人类丘脑内侧背侧核和室旁核中保守的细胞类型梯度	Schulmann, A.	PDF	N/A	A conserved cell-type gradient across the human mediodorsal and paraventricular thalamus
灵长类动物外侧前额叶皮层神经元中的脉冲频率适应是由内在特性和电路动态相互作用的结果。	Koch, N. A.	PDF	N/A	Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties and circuit dynamics
一棵根深蒂固的真核生物树揭示了它们的挖掘祖先起源。	Williamson, K.	PDF	N/A	A robustly rooted tree of eukaryotes reveals their excavate ancestry.
从聚合的染色质可及性数据推断基因型揭示了遗传调控机制	Wenz, B. M.	PDF	N/A	Genotype inference from aggregated chromatin accessibility data reveals genetic regulatory mechanisms
孕期接触丙戊酸会导致大鼠皮质和海马神经元结构和功能的性别特异性改变。	Williams, O. O. F.	PDF	N/A	Prenatal exposure to valproic acid induces sex-specific alterations in cortical and hippocampal neuronal structure and function in rats
Arc/Arg3.1 结合核多聚腺苷酸结合蛋白 RRM，并调控神经元活动依赖性的核斑点形成	Kanhema, T.	PDF	N/A	Arc/Arg3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles
在刺虫精子发生过程中重组、X染色体失活以及着丝粒蛋白的动态变化	Toubiana, W.	PDF	N/A	Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis
在秀丽隐杆线虫的受精囊中，肌动蛋白细胞骨架和顶端细胞连接处的张力受到受精囊解剖结构、排卵状态以及肌球蛋白激活的影响。	Sadeghian, F.	PDF	N/A	Tensions on the actin cytoskeleton and apical cell junctions in the C. elegans spermatheca are influenced by spermathecal anatomy, ovulation state and activation of myosin
化学伴侣——山梨醇可纠正罗伯茨突变体的粘附和翻译缺陷	BOSE, T.	PDF	N/A	Chemical chaperone - sorbitol corrects cohesion and translational defects in the Roberts mutant
Piezo1的机械感应通过PP2A-Akt轴调节牙周炎中的破骨细胞分化	Shindo, S.	PDF	N/A	Mechanosensing by Piezo1 regulates osteoclast differentiation via PP2A-Akt axis in periodontitis
Meckel-Gruber综合征蛋白TMEM67通过ADAMTS9蛋白酶解切割生成的两种功能形式介导Wnt信号传导和纤毛发生。	Ahmed, M.	PDF	N/A	Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis
缝隙连接蛋白1与Hippo通路在恶性黑色素瘤中的相互作用	Sayedyahossein, S.	PDF	N/A	Pannexin 1 crosstalk with the Hippo pathway in malignant melanoma
Zbtb38通过转录调控XIAP表达来抑制细胞凋亡。	Matsuda, E.	PDF	N/A	Zbtb38 inhibits apoptosis by transcriptionally regulating XIAP expression
银屑病样炎症诱导人角质形成细胞和成纤维细胞的线粒体功能和结构改变	Kulkoviene, G.	PDF	N/A	Psoriasis-like inflammation induces mitochondrial function and structure changes in human keratinocytes and fibroblasts
RCC1 耗竭导致蛋白质运输缺陷和微核破裂	Zych, M. G.	PDF	N/A	RCC1 depletion drives protein transport defects and rupture in micronuclei
细胞外囊泡的生物活性和潜在的临床应用价值取决于间充质基质细胞的克隆亚型。	Ioannou, S.	PDF	N/A	Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype
线粒体移植：一种治疗肝缺血/再灌注损伤的新型疗法	Mukkala, A. N.	PDF	N/A	Mitochondrial transplantation: a novel therapy for liver ischemia/reperfusion injury
巨轴突神经病变中突变的Gigaxonin与TDP-43及其他RNA结合蛋白相互作用	Phillips, C. L.	PDF	N/A	Gigaxonin, mutated in Giant Axonal Neuropathy, interacts with TDP-43 and other RNA binding proteins
培养条件差异性调控气管支气管基底干细胞的炎症微环境和细胞表型	Murthy, S.	PDF	N/A	Culture Conditions Differentially Regulate the Inflammatory Niche and Cellular Phenotype of Tracheo-Bronchial Basal Stem Cells
RTN4IP1对于线粒体复合物I组装和辅酶Q生物合成的最后阶段至关重要。	Olahova, M.	PDF	N/A	RTN4IP1 is essential for the final stages of mitochondrial complex I assembly and coenzyme Q biosynthesis
MLX的磷酸化作用稳定了ChREBP-MLX异四聚体在串联E-box上的结合，从而调控碳水化合物和脂质代谢。	Shimobayashi, M.	PDF	N/A	MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism
MLX磷酸化稳定了ChREBP-MLX异源四聚体在串联E-box上的结合，从而调控碳水化合物和脂质代谢。	Cadena del Castillo, C.	PDF	N/A	MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism
脂肪酸在膜脂和储存脂质之间的分配调控内质网膜的扩张。	Lysyganicz, P. K.	PDF	N/A	The partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion.
果蝇运动决策的时空动态	Lebovich, L.	PDF	N/A	Spatiotemporal dynamics of locomotor decisions in Drosophila melanogaster
卫星胶质细胞调节背根神经节中本体感受神经元的活动	Rabah, Y.	PDF	N/A	Satellite glial cells modulate proprioceptive neuron activity in dorsal root ganglia
水通道蛋白-4在嗅上皮中的表达和定位调节了气味诱发的反应和嗅觉驱动的行为	Lobraico, D.	PDF	N/A	The Aquaporin-4 expression and localization in the olfactory epithelium modulate the odorant-evoked responses and olfactory driven behavior
Hox基因，腹部A，控制果蝇中枢神经系统发育过程中神经干细胞的及时有丝分裂进入及其生长。	ARYA, R.	PDF	N/A	The Hox Gene, abdominal A controls timely mitotic entry of neural stem cell and their growth during CNS development in Drosophila
从组织到亚细胞层面：通过成像人类精密切割肺切片（PCLS）以深入了解大流行细菌或病毒感染	Eymieux, S.	PDF	N/A	From tissue to subcellular level : imaging human precision-cut lung slices (PCLS) to gain insight into pandemic bacterial or viral infections
阿尔茨海默病脑源性tau聚集物的特性定义了人类星形胶质细胞对tau的加工。	Reid, M. J.	PDF	N/A	Properties of Alzheimers disease brain-derived tau aggregates define tau processing by human astrocytes.
单次检测微尺度触觉特征	Reschechtko, S.	PDF	N/A	Single-shot detection of microscale tactile features
使用可调水凝胶解耦触觉湿润感知的冷暖与柔软度	Becerra, L. L.	PDF	N/A	Decoupling Coldness and Softness in Tactile Wetness Perception Using Tunable Hydrogels
牙龈卟啉单胞菌外膜囊泡改变了胚胎小鼠大脑中的神经元结构和Tau蛋白磷酸化	Bradley, A.	PDF	N/A	Porphyromonas gingivalis outer membrane vesicles alter neuronal architecture and Tau phosphorylation in the embryonic mouse brain
启动线索的感官背景会调节与动作目标相关的神经表征	Kreter, N.	PDF	N/A	Sensory context of initiation-cue modulates action goal-relevant neural representations
通过使用FluidFM挑选和放置神经球体，构建具有多种细胞类型的定义明确的神经网络	Vulic, K.	PDF	N/A	Constructing well-defined neural networks of multiple cell types by picking and placing of neuronal spheroids using FluidFM
脑-身互动影响从心智游移到对当前思维意识的状态转变	Shinagawa, K.	PDF	N/A	Brain-Body Interactions Influence the Transition from Mind Wandering to Awareness of Ongoing Thought
与内在电导相比，电路功能对突触电导的变化更为鲁棒。	Fournier, Z.	PDF	N/A	Circuit function is more robust to changes in synaptic than intrinsic conductances
双位点经颅交流电刺激对血氧水平依赖信号的即时调制在整个大脑中传播	Hiromitsu, K.	PDF	N/A	Immediate Modulation of the Blood Oxygenation Level-Dependent Signals by Dual-Site Transcranial Alternating Current Stimulation Propagates Across the Whole Brain
基于他人学习偏好的政策塑造解释了在社会观察下的冒险决策行为	Seon, H.	PDF	N/A	Policy shaping based on the learned preferences of others accounts for risky decision-making under social observation
全狨猴大脑的串行双光子断层扫描成像用于神经解剖学分析	Watakabe, A.	PDF	N/A	Serial Two-Photon Tomography Imaging of the whole marmoset brain for neuroanatomical analyses
一种灵活的高精度光声视网膜假体	Leong, A.	PDF	N/A	A flexible high-precision photoacoustic retinal prosthesis
听觉伪词的光谱-时间特征和语音特征对多种声音象征映射的差异性贡献	Lacey, S.	PDF	N/A	DIFFERENTIAL CONTRIBUTIONS OF THE SPECTRO-TEMPORAL AND VOCAL CHARACTERISTICS OF AUDITORY PSEUDOWORDS TO MULTIPLE SOUND-SYMBOLIC MAPPINGS
在小鼠中，周围炎症伴随有脑部血流减少。	Kazeem, A.	PDF	N/A	Peripheral Inflammation is accompanied by Cerebral Hypoperfusion in Mice
催产素通过道德框架挽救了特定情境下的超利他偏好	Zhang, H.	PDF	N/A	Oxytocin salvages context-specific hyperaltruistic preference through moral framing
计算机视觉引导下快速精准的啮齿动物颅内显微手术自动化	Navabi, Z. S.	PDF	N/A	Computer vision guided rapid and precise automated cranial microsurgeries in rodents
在β冠状病毒家族中，刺突S2域N-糖基化的保守作用	Yang, Q.	PDF	N/A	Conserved role of spike S2 domain N-glycosylation across beta-coronavirus family
英国诺福克地区2020年3月至2022年12月SARS-CoV-2的基因组流行病学	Hayles, E. H.	PDF	N/A	Genomic Epidemiology of SARS-CoV-2 in Norfolk, UK, March 2020 - December 2022
结核分枝杆菌必需转运蛋白A的结构与抑制机制	Khandelwal, N. K.	PDF	N/A	Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporterefflux protein A
Nsp1在DNA发夹处阻碍DNA聚合酶α的进程	Baranovskiy, A. G.	PDF	N/A	Nsp1 stalls DNA Polymerase alpha at DNA hairpins
SARS-CoV-2的主要蛋白酶（Mpro）通过激活凝血因子VII和FXII，在体外引发血浆凝固。	Pagotto, A.	PDF	N/A	The Main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII
六种铜绿假单胞菌噬菌体的全基因组序列，旨在用于研究和治疗	Rimon, A.	PDF	N/A	Complete Genome Sequence of Six Pseudomonas aeruginosa Bacteriophages aim for research and treatments
转录终止和抗终止对于整合接合元件Tn916的适应性和功能至关重要。	Wirachman, E. S.	PDF	N/A	Transcription termination and antitermination are critical for the fitness and function of the integrative and conjugative element Tn916
CLIC/GEEC途径调控HIV-1感染的巨噬细胞中颗粒的内吞作用及病毒包含体（VCC）的形成	Candor, K.	PDF	N/A	The CLIC/GEEC pathway regulates particle endocytosis and formation of the virus-containing compartment (VCC) in HIV-1-infected macrophages
绘制棒状细菌细胞表面的超微结构拓扑图	Isbilir, B.	PDF	N/A	Mapping the ultrastructural topology of the corynebacterial cell surface
谷氨酸棒杆菌PS2 S层的冷冻电镜结构与极性组装	Sogues, A.	PDF	N/A	Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicum
Lachancea thermotolerans中亚群特异性基因表达揭示了葡萄酒发酵过程中不同的代谢适应	VICENTE, J.	PDF	N/A	Subpopulation-specific gene expression in Lachancea thermotolerans uncovers distinct metabolic adaptations to wine fermentation
应用条形码测序技术提高恶性疟原虫遗传筛选的通量和复杂性	Muwhezi, A.	PDF	N/A	Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening
磷酸铁试剂法：一种用于研究植物根部细菌产生的氧化还原活性代谢物的工具	Giacalone, D.	PDF	N/A	The phospho-ferrozine assay: A tool to study bacterial redox-active metabolites produced at the plant root
与时间赛跑：描述奇瓦瓦沙漠中极度濒危的微生物绿洲的微生物多样性	Rodriguez-Cruz, U. E.	PDF	N/A	Running against the clock: describing microbial diversity in an extremely endangered microbial oasis in the Chihuahuan desert
志贺氏菌效应蛋白IpaH1.4促进RNF213的降解，并保护细胞质中的细菌免受干扰素诱导的泛素化作用。	Saavedra Sanchez, L.	PDF	N/A	The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
抗寄生虫药物塞拉菌素在耻垢分枝杆菌中产生抗药性的可能性不大，且取决于细胞壁的完整性。	Ezquerra-Aznarez, J. M.	PDF	N/A	Emergence of resistance to the antiparasitic selamectin in Mycobacterium smegmatis is improbable and contingent on cell wall integrity
PIP2促进CD43、PSGL-1和CD44整合入新生的HIV-1颗粒中。	Cardoso, R. d. S.	PDF	N/A	PIP2 promotes the incorporation of CD43, PSGL-1 and CD44 into nascent HIV-1 particles
评估选定植物提取物对采后白山药腐烂的抗菌潜力	Ibuot, A. A.	PDF	N/A	Assessing the Antimicrobial potentials of selected Plant Extracts against Post Harvest White Yam Rot
针对特定激酶底物的干预措施可缓解由克罗恩病相关LRRK2-N2081D变异体引发的结肠炎严重程度增加	Heaton, G. R.	PDF	N/A	Targeting Specific Kinase Substrates Rescues Increased Colitis Severity Induced by the Crohn's Disease-Linked LRRK2-N2081D Variant
线粒体拓扑异构酶I（Top1MT）可预防小鼠代谢功能障碍相关脂肪性肝炎（MASH）的发生。	Baechler, S. A.	PDF	N/A	Mitochondrial topoisomerase I (Top1MT) prevents the onset of metabolic dysfunction-associated steatohepatitis (MASH) in mice
一个南美洲库蚊（双翅目：蚊科）的DNA条形码库，并描述了亚属Melanoconion中的两种隐秘物种。	Talaga, S.	PDF	N/A	A DNA barcode library for Culex mosquitoes (Diptera: Culicidae) of South America with the description of two cryptic species of subgenus Melanoconion
JN.1衍生的LB.1、KP.2.3、KP.3和KP.3.1.1亚型的中和与稳定性	Li, P.	PDF	N/A	Neutralization and Stability of JN.1-derived LB.1, KP.2.3, KP.3 and KP.3.1.1 Subvariants
利用长读长技术对澳大利亚高山石龙子（Bassiana duperreyi）进行基因组组装与注释	Hanrahan, B. J.	PDF	N/A	A genome assembly and annotation for the Australian alpine skink Bassiana duperreyi using long-read technologies
对MKP5双特异性磷酸酶的别构调控的动态和结构见解	Skeens, E.	PDF	N/A	Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase
基于结构的PROTAC设计用于降解可溶性环氧化物水解酶	Schoenfeld, J.	PDF	N/A	STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE
驱动蛋白-8通过将其近端尾部结构域折叠成一个紧凑的螺旋束而形成二聚体。	Allingham, J. S.	PDF	N/A	Kinesin-8 motors dimerize by folding their proximal tail domain into a compact helical bundle
CRISPR-Cas9靶向链切割通过抑制复制提供了噬菌体抗性。	Nguyen, G. T.	PDF	N/A	CRISPR-Cas9 target-strand nicking provides phage resistance by inhibiting replication
基于人工智能的发现与低温电子显微镜结构解析：一种KATP通道药物伴侣蛋白	Elsheikh, A.	PDF	N/A	AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone
通过计算识别能够增加哺乳动物细胞中合成回路基因表达的小分子	Pisani, M.	PDF	N/A	Computational identification of small molecules for increased gene expression by synthetic circuits in mammalian cells
CryptKeeper：一种用于减少细菌中意外基因表达的负面设计工具	Roots, C. T.	PDF	N/A	CryptKeeper: a negative design tool for reducing unintentional gene expression in bacteria
内源性逆转录病毒通过激活MARCO介导的炎症反应来阻止逆转录病毒感染	Xuming, H.	PDF	N/A	Endogenous retroviruses activate MARCO-mediated inflammatory response to block retroviral infection
SARS-CoV-2 Nsp15 对抗 cGAS-STING 介导的抗病毒先天免疫反应	Lee, B.	PDF	N/A	SARS-CoV-2 Nsp15 antagonizes the cGAS-STING-mediated antiviral innate immune responses
工业和农业化学品对人类肠道细菌的非预期作用	Lindell, A. E.	PDF	N/A	Off-purpose activity of industrial and agricultural chemicals against human gut bacteria
转录组规模分析揭示了细菌RNA伴侣Hfq疏水核心中对小调控RNA稳定性至关重要的保守残基	McQuail, J.	PDF	N/A	Transcriptome-scale analysis uncovers conserved residues in the hydrophobic core of the bacterial RNA chaperone Hfq required for small regulatory RNA stability
环境抗生素抗性组：植物根系发育早期阶段HAE-1外排泵的选择	Simenel, O.	PDF	N/A	Environmental antibiotic resistome: selection of HAE-1 efflux pumps in early stages of plant root development
ADAR1 调控 ZBP1 介导的 PANoptosis 和心脏移植排斥反应	Lu, H.	PDF	N/A	ADAR1 orchestrates the ZBP1-mediated PANoptosis and heart transplant rejection
红珠之咒：由光毒性引起的成纤维细胞特异性珍珠项链线粒体表型	Hemel, I. M.	PDF	N/A	The curse of the red pearl: a fibroblast specific pearl-necklace mitochondrial phenotype caused by phototoxicity
使用MS Annika 3.0进行蛋白质组范围的不可切割交联鉴定揭示了秀丽隐杆线虫Box C/D复合物的结构	Birklbauer, M. J.	PDF	N/A	Proteome-wide non-cleavable crosslink identification with MS Annika 3.0 reveals the structure of the C. elegans Box C/D complex
哺乳动物与斑胸草雀之间突变和重组参数的保守性	Prentout, D.	PDF	N/A	Conservation of mutation and recombination parameters between mammals and zebra finch
共享的遗传架构将能量代谢、行为和抗饥饿能力沿着力量-耐力轴联系在一起	Erkosar, B.	PDF	N/A	Shared genetic architecture links energy metabolism, behavior and starvation resistance along a power-endurance axis
蜜蜂卵的成分随季节变化，并在母体急性病毒感染后发生变化	Chapman, A.	PDF	N/A	Honey bee egg composition changes seasonally and after acute maternal virus infection
控制蜜蜂（Apis mellifera）蜂王生长的社会和营养因素	Kama, O.	PDF	N/A	The Social and Nutritional Factors Controlling the Growth of Honey Bee (Apis mellifera) Queens
非线性树突整合支持单个神经元中的上下状态	Quaresima, A.	PDF	N/A	Nonlinear dendritic integration supports Up-Down states in single neurons
利用TMS-EEG研究在反应性和前瞻性运动抑制过程中GABA能抑制与谷氨酸能兴奋之间的复杂相互作用	Zhu, T.	PDF	N/A	Using TMS-EEG to study the intricate interplay between GABAergic inhibition and glutamatergic excitation during reactive and proactive motor inhibition
海马体神经元活动与行动计划相一致。	Zutshi, I.	PDF	N/A	Hippocampal neuronal activity is aligned with action plans
统计学习过程中期望的可分离动态效应。	McDermott, H. H.	PDF	N/A	Dissociable dynamic effects of expectation during statistical learning.
下丘脑-脑干回路控制着将安全置于基本需求之上的优先级。	Krauth, N.	PDF	N/A	A hypothalamus-brainstem circuit governs the prioritization of safety over essential needs
使用微图案化的玻璃上突触前模型解析突触前肌动蛋白的纳米级结构	Tumminia, S.	PDF	N/A	Deciphering the nanoscale architecture of presynaptic actin using a micropatterned presynapse-on-glass model
水田鼠的饮食是否与解释种群波动的植物假说一致？	Pinot, A.	PDF	N/A	Is water vole diet consistent with the plant hypothesis for explaining population fluctuations?
喜马拉雅地区濒危药用植物刺檗（Berberis lycium Royle）沿海拔梯度的植物-传粉者相互作用	Anjum, N.	PDF	N/A	Plant-Pollinator Interactions along the Altitudinal Gradient in Berberis lycium Royle: An Endangered Medicinal Plant Species of the Himalayan Region
埃及伊蚊入侵动态变化及其对秘鲁亚马逊地区农村社区的媒介传播疾病风险	Fikrig, K. M.	PDF	N/A	Changing dynamics of Aedes aegypti invasion and vector-borne disease risk for rural communities in the Peruvian Amazon
公共基因组数据库中高度受限基因的独特特征	Agrawal, P.	PDF	N/A	Unique Signatures of Highly Constrained Genes Across Publicly Available Genomic Databases
# BioRxiv 2024-09-04 Papers

标题	作者	PDF链接	代码仓库	Title
染色质阅读器Dido3是调控B细胞分化基因网络的调节因子。	Gutierrez del Burgo, F.	PDF	N/A	The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation
黄矢车菊（Centaurea solstitialis）的染色体规模参考基因组和基于RAD的遗传图谱揭示了与入侵性状相关的潜在结构变异和数量性状位点（QTLs）。	Reatini, B.	PDF	N/A	Chromosome-scale reference genome and RAD-based genetic map of yellow starthistle (Centaurea solstitialis) reveal putative structural variation and QTLs associated with invader traits
Shewanella fidelis 3313 噬菌体调控其运动性和生物膜形成：对强壮海鞘肠道定殖动态的影响	Natarajan, O.	PDF	N/A	Prophage regulation of Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta
蒙古沙鼠家族特定发声用法的无监督发现	Peterson, R. E.	PDF	N/A	Unsupervised discovery of family specific vocal usage in the Mongolian gerbil
动作电位的消失会诱导神经元之间的电耦合	Schloetter, M.	PDF	N/A	Annihilation of action potentials induces electrical coupling between neurons
通过灵长类抓握回路中与姿势相关的活动，对手部假肢进行精确的神经控制	Agudelo-Toro, A.	PDF	N/A	Accurate neural control of a hand prosthesis by posture-related activity in the primate grasping circuit
M3NetFlow：一种用于综合多组学数据分析的新型多尺度多跳图AI模型	Zhang, H.	PDF	N/A	M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis
GluK1海人藻受体中第9外显子剪接插入的功能意义	Dhingra, S.	PDF	N/A	Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
PARP14/TARG1调控的RACK1 MARylation循环驱动卵巢癌细胞中的应激颗粒动态变化	Challa, S.	PDF	N/A	A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells
广布性浮游植物巴氏藻（Bathycoccus）的生物学和基因组资源：对遗传多样性和主要结构变异的洞察	Dennu, L.	PDF	N/A	Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: Insights into genetic diversity and major structural variations
dact1/2调控非经典Wnt信号传导和钙蛋白酶8在胚胎趋同延伸和颅面形态发生中的遗传需求	Carroll, S. H.	PDF	N/A	Genetic requirement of dact1/2 to regulate noncanonical Wnt signaling and calpain 8 during embryonic convergent extension and craniofacial morphogenesis
人类中具有疾病表型的新进化基因揭示了由适应性创新和性选择塑造的功能富集模式。	Chen, J.	PDF	N/A	Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.
电子自旋极化与电荷动力学在蛋白质功能中的作用	Vyas, P.	PDF	N/A	The Role of Electron Spin-Polarizability and Charge Dynamics in Protein Function
欧亚小鳟（鲤科：Phoxinus phoxinus）染色体水平、单倍型解析的基因组组装与注释提供了单倍型多样性的证据。	Oriowo, T. O.	PDF	N/A	A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity
双酚A的质子转移对于激活核外启动的雌激素受体信号传导是必需的。	Medina-Gali, R. M.	PDF	N/A	PROTON TRANSFER FROM BISPHENOL-A IS REQUIRED TO ACTIVATE EXTRANUCLEAR-INITIATED ESTROGEN RECEPTOR SIGNALING
可解释的多模态机器学习（IMML）框架揭示了远端感觉运动性多发性神经病变的病理特征。	Nguyen, P. B.	PDF	N/A	The Interpretable Multimodal Machine Learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy
药物适应性癌细胞系中的抗药性模式反映了临床肿瘤中复杂的进化过程。	Grimsley, H. E.	PDF	N/A	Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors
干扰抑制仅在视网膜坐标中起作用。	Ilksoy, Y. A.	PDF	N/A	Distractor suppression operates exclusively in retinotopic coordinates
抑制性神经元中神经纤毛蛋白-2表达失调损害海马回路发育，导致自闭症-癫痫表型	Subramanian, D.	PDF	N/A	Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype
通过选择性繁殖的小鼠肠道微生物群中的罗伊氏乳杆菌增强了驯服性	Biswa, B. B.	PDF	N/A	Enhanced tameness by Limosilactobacillus reuteri from gut microbiota of selectively bred mice
2P-NucTag：用于功能性识别皮层神经元分子分析的按需光标记技术	Shi, J.	PDF	N/A	2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons
通过神经网络收敛揭示的视觉人类前额叶激活的文本相关功能	Shoham, A.	PDF	N/A	Text-related functionality of visual human pre-frontal activations revealed through neural network convergence
当前的基因组深度学习架构在草类物种间具有泛化能力，但在等位基因方面不具备泛化能力。	Wrightsman, T.	PDF	N/A	Current genomic deep learning architectures generalize across grass species but not alleles
整合脊椎动物神经管中空间和时间模式化的顺式调控逻辑	Zhang, I.	PDF	N/A	The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
母体肥胖可能通过增加DNMTs（DNA甲基转移酶）导致卵母细胞基因组过度甲基化，从而干扰后代的代谢。	Chao, S.	PDF	N/A	Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs
通过大型语言模型预测TET和DNMT3敲除突变体中的差异甲基化胞嘧啶	sereshki, s.	PDF	N/A	Predicting Differentially Methylated Cytosines in TET and DNMT3 Knockout Mutants via a Large Language Model
抗体依赖性增强在DENV感染的Wistar大鼠中的作用，作为登革热小鼠模型	Wihanto, L.	PDF	N/A	Role of antibody-dependent enhancement in DENV-infected Wistar rats as a dengue murine model
修正关系估计中的模型误设	Jewett, E. M.	PDF	N/A	Correcting model misspecification in relationship estimates
脂肪细胞中的同源域转录因子与产热作用：对人类UCP1的物种特异性及保守调控元件的见解	B. Toth, B.	PDF	N/A	Homeodomain transcription factors in adipocyte thermogenesis: insights into the species-specific and conserved regulatory elements of human UCP1
全基因组条件性降解标签文库在功能基因组学中的应用	Gameiro, E.	PDF	N/A	Genome-wide conditional degron libraries for functional genomics
一种高效预测自然物体感知相似性的高通量方法	Kaniuth, P.	PDF	N/A	A high-throughput approach for the efficient prediction of perceived similarity of natural objects
酒精通过刺激AMPK介导的TORC1、p70/S6K和核糖体生物合成的抑制，诱导神经嵴中p53介导的细胞凋亡。	Huang, Y.	PDF	N/A	Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis.
在社会变形虫Dictyostelium discoideum中，支配等级是线性的但较为浅显。	Broersma, C. M. E.	PDF	N/A	Dominance hierarchies are linear but shallow in the social amoeba Dictyostelium discoideum.
一个表示静息动作电位尖峰序列的数学序列	Keum, D.	PDF	N/A	A Mathematical Sequence Representing Tonic Action Potential Spike Trains
食肉真菌少孢节丛孢的捕食装置是一种表型系统，用于分离热诱导的过量铁	Zhou, J.	PDF	N/A	Trapping Devices of Carnivorous fungus Arthrobotrys oligospora is a Phenotypic System for Separating Thermally-Induced Excess Irons
纺织结构自动化模型发现：经编面料的独特力学特征	McCulloch, J. A.	PDF	N/A	Automated model discovery for textile structures:The unique mechanical signature of warp knitted fabrics
一氧化碳驱动的生物乙醇生产通过依赖钨的催化剂进行。	Lemaire, O. N.	PDF	N/A	Carbon monoxide-driven bioethanol production operates via a tungsten-dependent catalyst
非周期性和振荡系统构成了人类领域一般认知的基础	Lu, R.	PDF	N/A	Aperiodic and oscillatory systems underpinning human domain-general cognition
用于斑马鱼异种移植模型的自动化微量注射技术	Ding, Y.	PDF	N/A	Automated microinjection for zebrafish xenograft models
非洲慈鲷（Astatotilapia burtoni）的面部和体色与其社会等级有关。	Peros, M.	PDF	N/A	Facial and body colouration are linked to social rank in the African cichlid, Astatotilapia burtoni
葡萄糖激酶活性控制着β细胞的亚群，这些亚群交替主导胰岛Ca²⁺振荡。	Jin, E.	PDF	N/A	Glucokinase activity controls subpopulations of β-cells that alternately lead islet Ca2+ oscillations
穴样蛋白组装体将一个双层叶片的脂质排出，以组织和弯曲膜结构。	Doktorova, M.	PDF	N/A	Caveolin assemblies displace one bilayer leaflet to organize and bend membranes
乳腺癌基因表达的综合元分析	Nwosu, I. O.	PDF	N/A	A Comprehensive Meta-Analysis of Breast Cancer Gene Expression
在乙醇-CPP中追求再巩固：不同条件下的记忆再激活并未引发记忆的不稳定	Zacouteguy Boos, F.	PDF	N/A	Pursuing reconsolidation in ethanol-CPP: memory reactivation in different conditions did not trigger destabilization
远端超级增强子驱动癌细胞中异常的CXCL13表达，通过CXCR5-CXCL13轴促进生长和p53失调	Gothwal, S. K.	PDF	N/A	Distal super-enhancer drives aberrant CXCL13 expression in Cancer cells driving growth and p53 dysregulation via CXCR5-CXCL13 axis
人工自然杀伤细胞模拟系统设计，旨在靶向肿瘤细胞	Chugh, V.	PDF	N/A	Design of an Artificial Natural Killer Cell Mimicking System to Target Tumour Cells
多感官方法在心理意象中的应用：ALE元分析比较运动、视觉和听觉意象	Van Caenegem, E. E.	PDF	N/A	Multisensory approach in Mental Imagery: ALE meta-analyses comparing Motor, Visual and Auditory Imagery
深度对比学习实现了全基因组的虚拟筛选	Jia, Y.	PDF	N/A	Deep contrastive learning enables genome-wide virtual screening
一种利用计算机视觉和DNA条形码技术相结合的无脊椎动物生物监测方法	Blair, J. D.	PDF	N/A	A hybrid approach to invertebrate biomonitoring using computer vision and DNA metabarcoding
钠离子泄漏通道NALCN受到神经元SNARE复合体蛋白的调控。	Usher, S. G.	PDF	N/A	The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins
单细胞多组学揭示了糖原代谢差异，这些差异是物种特异性发育速度的基础	de la Porte, A.	PDF	N/A	Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development
活体成像与药代动力学：经皮注射的超声与X射线可成像的温度敏感水凝胶负载多柔比星与游离药物在猪体内的比较	Delgado, J. F.	PDF	N/A	In vivo Imaging and Pharmacokinetics of Percutaneously Injected Ultrasound and X-ray Imageable Thermosensitive Hydrogel loaded with Doxorubicin versus Free Drug in Swine
驱动哺乳动物脊髓内运动神经元特异性病毒载荷表达的顺式调控元件	Nagy, M. A.	PDF	N/A	Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cord
使用CRISPR-CAS9介导的LACZ基因编辑优化以马铃薯皮为葡萄糖源的工程大肠杆菌中脂肪酶的生产与特性分析	Minari, J. B.	PDF	N/A	CRISPR-CAS9 MEDIATED EDITING OF THE LACZ GENE FOR OPTIMIZING LIPASE PRODUCTION AND CHARACTERIZATION IN ENGINEERED ESCHERICHIA COLI USING POTATO PEEL AS A GLUCOSE SOURCE
关于微生物活动在养分循环和转化中的作用及其对土壤肥力和作物生产力的影响的系统综述	Zeleke, T. B.	PDF	N/A	Systematic Review on the Role of Microbial Activities on Nutrient Cycling and Transformation Implication for Soil Fertility and Crop Productivity
IgSeqR：一种从非选择性RNA测序数据中识别、组装和表征全长肿瘤免疫球蛋白转录本的协议	Bryant, D.	PDF	N/A	IgSeqR: a protocol for the identification, assembly, and characterization of full-length tumor Immunoglobulin transcripts from unselected RNA sequencing data
时间基因组动力学塑造多发性骨髓瘤的临床轨迹	MAURA, F.	PDF	N/A	Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma
一项多维度的泛癌分析揭示了CDKN1A作为免疫学和预后生物标志物的作用	Shi, L.	PDF	N/A	A multidimensional Pan-cancer analysis of CDKN1A identifies CDKN1A as an Immunological and Prognostic Biomarker
视觉注意对阿拉伯字母识别及阅读习得的影响	Ghandour, A.	PDF	N/A	The influence of visual attention on letter recognition and reading acquisition in Arabic
音乐训练并不增强听觉系统早期阶段的神经声音编码：一项大规模多中心研究	Whiteford, K. L.	PDF	N/A	Musical training does not enhance neural sound encoding at early stages of the auditory system: A large-scale multisite investigation
脑室周围及深部白质高信号阈值在衰老中的变化：指数级进展、认知衰退及神经解剖结构萎缩	Gupta, N. K.	PDF	N/A	Periventricular and Deep White Matter Hyperintensity Thresholds in Aging: Exponential Progression, Cognitive Decline, and Neuroanatomic Atrophy
有药物使用障碍家族史的青年大脑活动动态的性别特异性差异	Schilling, L. S.	PDF	N/A	Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder
整合素激活耶尔森菌蛋白入侵素维持原代上皮细胞的长期扩展，形成二维类器官片层	Wijnakker, J.	PDF	N/A	Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets
小鼠CDK2的不同剪接异构体在有丝分裂和减数分裂过程中发挥功能冗余作用	Palmer, N.	PDF	N/A	Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division
哥斯达黎加生态系统服务付费计划的大规模恢复	Delgado, G. L.	PDF	N/A	Large-scale recovery in Costa Rica's Payment for Ecosystem Service Program
引入白三叶草（Trifolium repens L.）后抗旱策略的演变	Hendrickson, B. T.	PDF	N/A	Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.)
利用牛津纳米孔长读长测序技术进行生态基因组学实践训练的工作流程	Foster, R.	PDF	N/A	A workflow for practical training in ecological genomics using Oxford Nanopore long-read sequencing
多组学视角下的人类健康：狩猎采集者、农牧民与西方都市人群的肠道微生物群	Singh, H.	PDF	N/A	Multiomic Insights into Human Health: Gut Microbiomes of Hunter-Gatherer, Agropastoral, and Western Urban Populations
物理机制揭示了细菌在鞭毛数量超过临界值时减速的现象	Tatulea-Codrean, M.	PDF	N/A	Physical mechanism reveals bacterial slowdown above a critical number of flagella
抗生素前与抗生素后时代：对耐药性历史传播的洞察	Cazares, A.	PDF	N/A	Pre and Post antibiotic epoch: insights into the historical spread of antimicrobial resistance
热应激使斑马鱼胚胎对神经毒性和心脏毒性更加敏感。	Haapanen-Saaristo, A.-M.	PDF	N/A	Heat stress sensitizes zebrafish embryos to neurological and cardiac toxicity.
灵长类尾状核在多模态决策中的独特神经网络及其关键作用	ZENG, Z.	PDF	N/A	Distinct neural manifolds and critical roles of primate caudate nucleus in multimodal decision-making
GC含量对沿物种形成连续体分化区域形成的贡献	Ke, F.	PDF	N/A	Contribution of GC content to differentiated region formation along a speciation continuum
神经元自噬体被转运至星形胶质细胞进行降解。	Linda, K.	PDF	N/A	Neuronal autophagosomes are transported to astrocytes for degradation
权力不对称破坏了社会困境中的互惠合作	Colnaghi, M.	PDF	N/A	Power asymmetry destabilizes reciprocal cooperation in social dilemmas
从影响力指标和开放科学到传播研究：记者对学术争议的认知	Fleerackers, A.	PDF	N/A	From impact metrics and open science to communicating research: Journalists' awareness of academic controversies
波多黎各非裔后裔的基因血统展现了非洲散居人口多样的历史背景。	Nieves-Colon, M. A.	PDF	N/A	Genetic ancestry in Puerto Rican Afro-descendants illustrates diverse histories of African diasporic populations
主要抑郁症的基因年龄差距估计（GAGE）：基于基因表达的惩罚性生物年龄模型	Li, Y.	PDF	N/A	Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression
靶向FOXO4-p53相互作用的肽类抑制剂，诱导衰老癌细胞特异性凋亡	Kang, D.	PDF	N/A	Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis
优化针对SARS-CoV-2变种的中和抗体的高通量多重检测方法。	Ashley, C. L.	PDF	N/A	Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants.
沙门氏菌中的RNase III通过降低宿主免疫反应来增强细菌的致病性。	CHAN, K.-w. B.	PDF	N/A	RNase III in Salmonella Enteritidis enhances bacterial virulence by reducing host immune responses
细菌通过趋同进化对宿主生态位依赖性营养物质的可用性进行代谢重塑	Pickering, A.	PDF	N/A	Bacterial metabolic remodelling by convergent evolution in response to host niche-dependent nutrient availability
丝状蓝藻中的昼夜表达动力学	Kennedy, S. J.	PDF	N/A	Diel expression dynamics in filamentous cyanobacteria
化学遗传相互作用阐明在感染期间控制结核病抗生素效力的途径	Oluoch, P. O.	PDF	N/A	Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection
KatG在msr缺失的鼠伤寒沙门氏菌中抵御H2O2应激的补偿作用	Lalhmangaihzuali, L.	PDF	N/A	Compensatory role of KatG in defending H2O2 stress in msr deletion strain of Salmonella Typhimurium
在埃希氏大肠杆菌菌株中，利用微型核酸酶TnpB、IscB和enIscB进行基因编辑的特征分析	Li, Q.	PDF	N/A	Characterization the gene editing with miniature nucleases TnpB, IscB and enIscB in Escherichia coli strains
反硝化除磷生物反应器中一氧化二氮的生成、机理及建模	Farmer, M.	PDF	N/A	Nitrous oxide production, mechanisms, and modeling from a denitrifying phosphorus removal bioreactor
微生物代谢酶、途径及微生物宿主在废水中共代谢降解有机微污染物中的作用	Lyu, B.	PDF	N/A	Microbial Metabolic Enzymes, Pathways and Microbial Hosts for Co-Metabolic Degradation of Organic Micropollutants in Wastewater
与克罗恩病相关的E. coli采用不同的策略来定殖巨噬细胞。	Bruder, E.	PDF	N/A	E. coli associated with Crohn's disease exhibit distinct strategies to colonize macrophages
TgGloL是一种非典型的含甘油醛/挥发性有机化合物（VOC）结构域的顶质体蛋白，对弓形虫的生长至关重要。	Sanchez, S. G.	PDF	N/A	TgGloL is an atypical glyoxalase/VOC domain-containing apicoplast protein that is important for the growth of Toxoplasma
好氧颗粒形成过程中及进水改造后Accumulibacter及其邻近群落表达的多条胞外聚合物途径	Cardona, L.	PDF	N/A	Multiple extracellular polymeric substances pathways expressed by Accumulibacter and the flanking community during aerobic granule formation and after influent modification
军团菌肺炎铜耐药性：遗传因素和宿主细胞的作用。	Cameron, G.	PDF	N/A	Copper resistance in Legionella pneumophila: role of genetic factors and host cells.
USP37通过TRAIP防止应激复制体过早解体。	Kochenova, O. V.	PDF	N/A	USP37 prevents premature disassembly of stressed replisomes by TRAIP
通过测序进行全基因组RNA-蛋白质相互作用图谱绘制	Qi, Z.	PDF	N/A	Genome-Wide Mapping of RNA-Protein Associations via Sequencing
通过tRNA剪切，将tRNA同工解码器重新用于非经典功能	Bhatter, N.	PDF	N/A	Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage
神经生长因子trans-Banglene的蛋白质组学研究揭示了其与铁稳态的潜在联系	Gunawardana, P. W.	PDF	N/A	Proteomic Investigation of Neurotrophic trans-Banglene Reveals Potential Link to Iron Homeostasis
选择性多腺苷酸化调节因子CFIm25促进巨噬细胞分化并激活NF-κβ通路	Mukherjee, S.	PDF	N/A	The alternative polyadenylation regulator CFIm25 promotes macrophage differentiation and activates the NF-κβ pathway
SARS-CoV-2 KP.3与ACE2之间增强亲和力的上位效应的结构和分子基础	Feng, L.	PDF	N/A	Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2
使用CLEANSER对单细胞CRISPR筛选中的环境gRNA进行特征描述和生物信息学过滤	Liu, S.	PDF	N/A	Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER
LevSeq：快速生成序列功能数据，用于定向进化和机器学习	Long, Y.	PDF	N/A	LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning
用于生物组织中单个细胞类型的全面分子图谱的关联成像	Yang, M.	PDF	N/A	Correlative Imaging for Comprehensive Molecular Mapping of Individual Cell Types in Biological Tissues
辣椒疫霉效应蛋白AVR3a11的动力学确认了核心WY结构域的折叠	Tolchard, J.	PDF	N/A	Dynamics in the Phytophthora capsici effector AVR3a11 confirm the core WY domain fold
LEA_4基序单独作用并与协同的共溶质结合，以在脱水过程中保护不稳定的酶。	Nicholson, V.	PDF	N/A	LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation
具有超广底物谱的PL35家族糖胺聚糖裂解酶的晶体结构与催化机制	Wei, L.	PDF	N/A	Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum
通过冷冻电子显微镜观察铁蛋白的有机-无机界面	Sen, S.	PDF	N/A	Observation of the protein-inorganic interface of ferritin by cryo-electron microscopy
甜蜜的科学：利用光学衍射断层成像技术探究果糖和葡萄糖对棕色脂肪细胞分化的影响	Anantha, P.	PDF	N/A	Sweet science: Exploring the impact of fructose and glucose on brown adipocyte differentiation using optical diffraction tomography
一种新型极端嗜盐绿藻——太平洋衣藻（Chlamydomonas pacifica）的描述及其作为生物技术宿主的潜力	Dutra Molino, J. V.	PDF	N/A	Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host
线粒体呼吸链的细胞内结构	Waltz, F.	PDF	N/A	In-cell architecture of the mitochondrial respiratory chain
从MetaCore网络中提取的成纤维细胞特异性蛋白质-蛋白质相互作用与心肌纤维化相关	Frahm, K. M.	PDF	N/A	Fibroblast-specific protein-protein interactions for myocardial fibrosis from MetaCore network
一个3D子宫内膜芯片揭示了胚胎来源因子CAPG和PDI在胚胎-子宫内膜交流中的作用	Tinning, H.	PDF	N/A	A 3D endometrium-on-a-chip reveals the role of conceptus-derived factors CAPG and PDI in conceptus-endometrial communication
多基因障碍阻止性染色体转变	Muralidhar, P.	PDF	N/A	Polygenic barriers to sex chromosome turnover
在患者层面建模意识障碍揭示了网络对诊断的影响与局部节点参数在预后中的作用	Zonca, L.	PDF	N/A	Modeling disorders of consciousness at the patient level reveals the network's influence on the diagnosis vs the local node parameters role in prognosis
# BioRxiv 2024-09-04 Papers

标题	作者	PDF链接	代码仓库	Title
染色质阅读器Dido3是调控B细胞分化基因网络的调节因子。	Gutierrez del Burgo, F.	PDF	N/A	The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation
黄矢车菊（Centaurea solstitialis）的染色体规模参考基因组和基于RAD的遗传图谱揭示了与入侵性状相关的潜在结构变异和数量性状位点（QTLs）。	Reatini, B.	PDF	N/A	Chromosome-scale reference genome and RAD-based genetic map of yellow starthistle (Centaurea solstitialis) reveal putative structural variation and QTLs associated with invader traits
Shewanella fidelis 3313 运动性和生物膜形成的噬菌体调控：对 Ciona robusta 肠道定殖动态的影响	Natarajan, O.	PDF	N/A	Prophage regulation of Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta
在没有监督的情况下，发现蒙古沙鼠家族特有的发声使用	Peterson, R. E.	PDF	N/A	Unsupervised discovery of family specific vocal usage in the Mongolian gerbil
动作电位的消失会诱导神经元之间的电耦合	Schloetter, M.	PDF	N/A	Annihilation of action potentials induces electrical coupling between neurons
通过灵长类抓握回路中与姿势相关的活动，实现对手部假肢的精确神经控制。	Agudelo-Toro, A.	PDF	N/A	Accurate neural control of a hand prosthesis by posture-related activity in the primate grasping circuit
M3NetFlow：一种用于综合多组学数据分析的新型多尺度多跳图AI模型	Zhang, H.	PDF	N/A	M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis
GluK1海人藻酸受体外显子9剪接插入的功能意义	Dhingra, S.	PDF	N/A	Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
PARP14/TARG1调控的RACK1 MARylation循环驱动卵巢癌细胞中的应激颗粒动态变化	Challa, S.	PDF	N/A	A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells
全球浮游植物Bathycoccus的生物和基因组资源：遗传多样性和主要结构变异的见解	Dennu, L.	PDF	N/A	Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: Insights into genetic diversity and major structural variations
dact1/2 调控非经典 Wnt 信号通路及胚胎期趋同延伸和颅面形态发生过程中 calpain 8 的遗传需求	Carroll, S. H.	PDF	N/A	Genetic requirement of dact1/2 to regulate noncanonical Wnt signaling and calpain 8 during embryonic convergent extension and craniofacial morphogenesis
具有疾病表现型的人类进化新基因揭示了由适应性创新和性选择塑造的功能富集模式。	Chen, J.	PDF	N/A	Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.
电子自旋极化与电荷动力学在蛋白质功能中的作用	Vyas, P.	PDF	N/A	The Role of Electron Spin-Polarizability and Charge Dynamics in Protein Function
欧亚小鳊（鲤科：Phoxinus phoxinus）的染色体水平、单倍型解析的基因组组装与注释提供了单倍型多样性的证据。	Oriowo, T. O.	PDF	N/A	A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity
双酚A的质子转移对于激活核外启动的雌激素受体信号传导是必需的。	Medina-Gali, R. M.	PDF	N/A	PROTON TRANSFER FROM BISPHENOL-A IS REQUIRED TO ACTIVATE EXTRANUCLEAR-INITIATED ESTROGEN RECEPTOR SIGNALING
可解释的多模态机器学习（IMML）框架揭示了远端感觉运动多发性神经病变的病理特征。	Nguyen, P. B.	PDF	N/A	The Interpretable Multimodal Machine Learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy
药物适应的癌细胞系中的抗药性模式反映了临床肿瘤中复杂的进化过程。	Grimsley, H. E.	PDF	N/A	Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors
干扰抑制仅在视网膜坐标中运作	Ilksoy, Y. A.	PDF	N/A	Distractor suppression operates exclusively in retinotopic coordinates
抑制性神经元中神经纤毛蛋白-2表达失调会损害海马回路发育，导致自闭症-癫痫表型	Subramanian, D.	PDF	N/A	Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype
通过从选择性繁殖小鼠的肠道微生物群中提取的罗伊氏乳杆菌增强驯化效果	Biswa, B. B.	PDF	N/A	Enhanced tameness by Limosilactobacillus reuteri from gut microbiota of selectively bred mice
2P-NucTag：用于功能性识别皮层神经元分子分析的按需光标记技术	Shi, J.	PDF	N/A	2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons
通过神经网络收敛揭示的视觉人类前额叶激活的文本相关功能	Shoham, A.	PDF	N/A	Text-related functionality of visual human pre-frontal activations revealed through neural network convergence
当前的基因组深度学习架构能够在不同草种之间进行泛化，但不能在等位基因之间进行泛化。	Wrightsman, T.	PDF	N/A	Current genomic deep learning architectures generalize across grass species but not alleles
整合脊椎动物神经管空间和时间模式化的顺式调控逻辑	Zhang, I.	PDF	N/A	The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
母体肥胖可能通过增加DNMTs（DNA甲基转移酶）导致卵母细胞基因组高甲基化，从而扰乱后代的新陈代谢。	Chao, S.	PDF	N/A	Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs
通过大型语言模型预测TET和DNMT3敲除突变体中的差异甲基化胞嘧啶	sereshki, s.	PDF	N/A	Predicting Differentially Methylated Cytosines in TET and DNMT3 Knockout Mutants via a Large Language Model
抗体依赖性增强作用在登革病毒感染的Wistar大鼠中的作用，作为登革热小鼠模型	Wihanto, L.	PDF	N/A	Role of antibody-dependent enhancement in DENV-infected Wistar rats as a dengue murine model
修正关系估计中的模型设定误差	Jewett, E. M.	PDF	N/A	Correcting model misspecification in relationship estimates
脂肪细胞中同源结构域转录因子在产热中的作用：对人类UCP1物种特异性和保守调控元件的见解	B. Toth, B.	PDF	N/A	Homeodomain transcription factors in adipocyte thermogenesis: insights into the species-specific and conserved regulatory elements of human UCP1
全基因组条件性降解标签文库用于功能基因组学研究	Gameiro, E.	PDF	N/A	Genome-wide conditional degron libraries for functional genomics
一种高效预测自然物体感知相似度的高通量方法	Kaniuth, P.	PDF	N/A	A high-throughput approach for the efficient prediction of perceived similarity of natural objects
酒精通过刺激AMPK介导的对TORC1、p70/S6K及核糖体生物合成的抑制，诱导神经嵴中p53介导的凋亡。	Huang, Y.	PDF	N/A	Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis.
在社会变形虫Dictyostelium discoideum中，支配等级是线性的但较为浅显。	Broersma, C. M. E.	PDF	N/A	Dominance hierarchies are linear but shallow in the social amoeba Dictyostelium discoideum.
一个表示紧张性动作电位放电序列的数学序列	Keum, D.	PDF	N/A	A Mathematical Sequence Representing Tonic Action Potential Spike Trains
食肉真菌少孢节丛孢的捕食装置是一种表型系统，用于分离热诱导的过量铁	Zhou, J.	PDF	N/A	Trapping Devices of Carnivorous fungus Arthrobotrys oligospora is a Phenotypic System for Separating Thermally-Induced Excess Irons
纺织结构自动模型发现：经编面料的独特力学特征	McCulloch, J. A.	PDF	N/A	Automated model discovery for textile structures:The unique mechanical signature of warp knitted fabrics
一氧化碳驱动的生物乙醇生产通过依赖钨的催化剂进行。	Lemaire, O. N.	PDF	N/A	Carbon monoxide-driven bioethanol production operates via a tungsten-dependent catalyst
非周期性和振荡系统构成了人类领域一般认知的基础。	Lu, R.	PDF	N/A	Aperiodic and oscillatory systems underpinning human domain-general cognition
用于斑马鱼异种移植模型的自动微量注射技术	Ding, Y.	PDF	N/A	Automated microinjection for zebrafish xenograft models
非洲丽鱼（Astatotilapia burtoni）的面部和体色与社会地位有关。	Peros, M.	PDF	N/A	Facial and body colouration are linked to social rank in the African cichlid, Astatotilapia burtoni
葡萄糖激酶活性控制着β细胞的亚群，这些亚群交替引导胰岛Ca2+振荡。	Jin, E.	PDF	N/A	Glucokinase activity controls subpopulations of β-cells that alternately lead islet Ca2+ oscillations
穴样蛋白组装体使一片双层膜叶发生移位，以组织和弯曲膜结构。	Doktorova, M.	PDF	N/A	Caveolin assemblies displace one bilayer leaflet to organize and bend membranes
乳腺癌基因表达的综合元分析	Nwosu, I. O.	PDF	N/A	A Comprehensive Meta-Analysis of Breast Cancer Gene Expression
在乙醇-CPP中追求再巩固：不同条件下的记忆再激活并未触发不稳定性	Zacouteguy Boos, F.	PDF	N/A	Pursuing reconsolidation in ethanol-CPP: memory reactivation in different conditions did not trigger destabilization
远端超级增强子驱动癌细胞中异常的CXCL13表达，通过CXCR5-CXCL13轴促进生长并导致p53失调	Gothwal, S. K.	PDF	N/A	Distal super-enhancer drives aberrant CXCL13 expression in Cancer cells driving growth and p53 dysregulation via CXCR5-CXCL13 axis
人工自然杀伤细胞模拟系统设计，以靶向肿瘤细胞	Chugh, V.	PDF	N/A	Design of an Artificial Natural Killer Cell Mimicking System to Target Tumour Cells
多感官方法在心理意象中的应用：比较运动、视觉和听觉意象的ALE元分析	Van Caenegem, E. E.	PDF	N/A	Multisensory approach in Mental Imagery: ALE meta-analyses comparing Motor, Visual and Auditory Imagery
深度对比学习实现了全基因组的虚拟筛选。	Jia, Y.	PDF	N/A	Deep contrastive learning enables genome-wide virtual screening
一种结合计算机视觉和DNA条形码技术的无脊椎动物生物监测混合方法	Blair, J. D.	PDF	N/A	A hybrid approach to invertebrate biomonitoring using computer vision and DNA metabarcoding
钠泄漏通道NALCN受神经元SNARE复合体蛋白的调控。	Usher, S. G.	PDF	N/A	The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins
单细胞多组学揭示了物种特异性发育速度差异背后的糖原代谢差异	de la Porte, A.	PDF	N/A	Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development
皮下注射超声和X射线可成像的载有阿霉素的热敏水凝胶与游离药物在小猪体内的成像和药代动力学比较	Delgado, J. F.	PDF	N/A	In vivo Imaging and Pharmacokinetics of Percutaneously Injected Ultrasound and X-ray Imageable Thermosensitive Hydrogel loaded with Doxorubicin versus Free Drug in Swine
驱动哺乳动物脊髓内运动神经元特异性病毒载体表达的顺式调控元件	Nagy, M. A.	PDF	N/A	Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cord
利用CRISPR-CAS9介导的LACZ基因编辑优化以马铃薯皮为葡萄糖源的工程大肠杆菌中脂肪酶的生产与特性分析	Minari, J. B.	PDF	N/A	CRISPR-CAS9 MEDIATED EDITING OF THE LACZ GENE FOR OPTIMIZING LIPASE PRODUCTION AND CHARACTERIZATION IN ENGINEERED ESCHERICHIA COLI USING POTATO PEEL AS A GLUCOSE SOURCE
系统综述：微生物活动在养分循环与转化中的作用及其对土壤肥力和作物生产力的影响	Zeleke, T. B.	PDF	N/A	Systematic Review on the Role of Microbial Activities on Nutrient Cycling and Transformation Implication for Soil Fertility and Crop Productivity
IgSeqR：一种从非选择性RNA测序数据中识别、组装和表征全长肿瘤免疫球蛋白转录本的协议	Bryant, D.	PDF	N/A	IgSeqR: a protocol for the identification, assembly, and characterization of full-length tumor Immunoglobulin transcripts from unselected RNA sequencing data
时间基因组动力学塑造多发性骨髓瘤的临床轨迹	MAURA, F.	PDF	N/A	Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma
一项多维度的泛癌分析揭示了CDKN1A作为免疫学和预后生物标志物的身份	Shi, L.	PDF	N/A	A multidimensional Pan-cancer analysis of CDKN1A identifies CDKN1A as an Immunological and Prognostic Biomarker
视觉注意对阿拉伯字母识别及阅读习得的影响	Ghandour, A.	PDF	N/A	The influence of visual attention on letter recognition and reading acquisition in Arabic
音乐训练并不增强听觉系统早期阶段的神经声音编码：一项大规模多中心研究	Whiteford, K. L.	PDF	N/A	Musical training does not enhance neural sound encoding at early stages of the auditory system: A large-scale multisite investigation
脑室周围和深部白质高信号阈值在衰老中的变化：指数级进展、认知衰退与神经解剖学萎缩	Gupta, N. K.	PDF	N/A	Periventricular and Deep White Matter Hyperintensity Thresholds in Aging: Exponential Progression, Cognitive Decline, and Neuroanatomic Atrophy
有物质使用障碍家族史的青少年大脑活动动态的性别特异性差异	Schilling, L. S.	PDF	N/A	Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder
整合素激活耶尔森菌蛋白Invasin维持原代上皮细胞长期扩展为二维类器官片	Wijnakker, J.	PDF	N/A	Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets
小鼠CDK2的不同剪接异构体在有丝分裂和减数分裂过程中发挥功能冗余作用	Palmer, N.	PDF	N/A	Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division
哥斯达黎加生态系统服务付费计划的大规模恢复	Delgado, G. L.	PDF	N/A	Large-scale recovery in Costa Rica's Payment for Ecosystem Service Program
引入白三叶草（Trifolium repens L.）后抗旱策略的演变	Hendrickson, B. T.	PDF	N/A	Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.)
使用牛津纳米孔长读长测序进行生态基因组学实践培训的工作流程	Foster, R.	PDF	N/A	A workflow for practical training in ecological genomics using Oxford Nanopore long-read sequencing
多组学视角下的人类健康：狩猎采集者、农牧民和西方城市人口的肠道微生物群	Singh, H.	PDF	N/A	Multiomic Insights into Human Health: Gut Microbiomes of Hunter-Gatherer, Agropastoral, and Western Urban Populations
物理机制揭示了细菌在鞭毛数量超过临界值时减速的现象	Tatulea-Codrean, M.	PDF	N/A	Physical mechanism reveals bacterial slowdown above a critical number of flagella
抗生素前与抗生素后时代：对抗生素耐药性历史传播的洞察	Cazares, A.	PDF	N/A	Pre and Post antibiotic epoch: insights into the historical spread of antimicrobial resistance
热应激使斑马鱼胚胎对神经毒性和心脏毒性更加敏感。	Haapanen-Saaristo, A.-M.	PDF	N/A	Heat stress sensitizes zebrafish embryos to neurological and cardiac toxicity.
灵长类尾状核在多模态决策中的独特神经结构及其关键作用	ZENG, Z.	PDF	N/A	Distinct neural manifolds and critical roles of primate caudate nucleus in multimodal decision-making
GC含量对物种形成连续体中分化区域形成的贡献	Ke, F.	PDF	N/A	Contribution of GC content to differentiated region formation along a speciation continuum
神经元自噬体被运输到星形胶质细胞中进行降解	Linda, K.	PDF	N/A	Neuronal autophagosomes are transported to astrocytes for degradation
权力不对称破坏了社会困境中的互惠合作	Colnaghi, M.	PDF	N/A	Power asymmetry destabilizes reciprocal cooperation in social dilemmas
从影响力指标和开放科学到传播研究：记者对学术争议的认知	Fleerackers, A.	PDF	N/A	From impact metrics and open science to communicating research: Journalists' awareness of academic controversies
波多黎各非裔后裔的基因血统展示了非洲散居人口的多样历史。	Nieves-Colon, M. A.	PDF	N/A	Genetic ancestry in Puerto Rican Afro-descendants illustrates diverse histories of African diasporic populations
主要抑郁症的基因年龄差距估计（GAGE）：使用基因表达的惩罚性生物年龄模型	Li, Y.	PDF	N/A	Gene Age Gap Estimate (GAGE) for major depressive disorder: a penalized biological age model using gene expression
靶向FOXO4-p53相互作用的肽类抑制剂，诱导衰老癌细胞特异性凋亡	Kang, D.	PDF	N/A	Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis
优化一种多重、高通量检测方法以测量针对SARS-CoV-2变种的中和抗体。	Ashley, C. L.	PDF	N/A	Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants.
沙门氏菌中的RNase III通过降低宿主免疫反应来增强细菌的致病性。	CHAN, K.-w. B.	PDF	N/A	RNase III in Salmonella Enteritidis enhances bacterial virulence by reducing host immune responses
细菌代谢的重塑通过趋同进化对宿主生态位依赖的营养物质可用性做出反应	Pickering, A.	PDF	N/A	Bacterial metabolic remodelling by convergent evolution in response to host niche-dependent nutrient availability
丝状蓝藻中的昼夜表达动力学	Kennedy, S. J.	PDF	N/A	Diel expression dynamics in filamentous cyanobacteria
化学遗传相互作用阐明感染期间控制结核病抗生素疗效的途径	Oluoch, P. O.	PDF	N/A	Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection
KatG在msr缺失型沙门氏菌Typhimurium中抵御H2O2应激的补偿作用	Lalhmangaihzuali, L.	PDF	N/A	Compensatory role of KatG in defending H2O2 stress in msr deletion strain of Salmonella Typhimurium
在埃希氏大肠杆菌菌株中，对使用微型核酸酶TnpB、IscB和enIscB进行基因编辑的特性进行了研究。	Li, Q.	PDF	N/A	Characterization the gene editing with miniature nucleases TnpB, IscB and enIscB in Escherichia coli strains
一株脱氮除磷生物反应器中氧化亚氮的产生、机理及模型化研究	Farmer, M.	PDF	N/A	Nitrous oxide production, mechanisms, and modeling from a denitrifying phosphorus removal bioreactor
微生物代谢酶、途径及共代谢降解有机微污染物所涉及的微生物宿主在废水处理中的作用	Lyu, B.	PDF	N/A	Microbial Metabolic Enzymes, Pathways and Microbial Hosts for Co-Metabolic Degradation of Organic Micropollutants in Wastewater
与克罗恩病相关的E. coli表现出独特的策略来定殖巨噬细胞	Bruder, E.	PDF	N/A	E. coli associated with Crohn's disease exhibit distinct strategies to colonize macrophages
TgGloL是一种非典型的含甘油醛/挥发性有机化合物（VOC）域的顶质体蛋白，对弓形虫的生长至关重要。	Sanchez, S. G.	PDF	N/A	TgGloL is an atypical glyoxalase/VOC domain-containing apicoplast protein that is important for the growth of Toxoplasma
好氧颗粒形成过程中及进水改造后Accumulibacter及其相邻群落表达的多条胞外聚合物途径	Cardona, L.	PDF	N/A	Multiple extracellular polymeric substances pathways expressed by Accumulibacter and the flanking community during aerobic granule formation and after influent modification
铜对军团菌肺炎的抗性：遗传因素和宿主细胞的作用。	Cameron, G.	PDF	N/A	Copper resistance in Legionella pneumophila: role of genetic factors and host cells.
USP37通过TRAIP防止应激复制体过早解体	Kochenova, O. V.	PDF	N/A	USP37 prevents premature disassembly of stressed replisomes by TRAIP
通过测序进行全基因组RNA-蛋白质相互作用图谱绘制	Qi, Z.	PDF	N/A	Genome-Wide Mapping of RNA-Protein Associations via Sequencing
通过tRNA剪切重新利用tRNA同义解码器用于非经典功能	Bhatter, N.	PDF	N/A	Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage
神经滋养性反式-Banglene的蛋白质组学研究揭示了与铁稳态的潜在联系	Gunawardana, P. W.	PDF	N/A	Proteomic Investigation of Neurotrophic trans-Banglene Reveals Potential Link to Iron Homeostasis
选择性多腺苷酸化调节因子CFIm25促进巨噬细胞分化并激活NF-κβ通路	Mukherjee, S.	PDF	N/A	The alternative polyadenylation regulator CFIm25 promotes macrophage differentiation and activates the NF-κβ pathway
SARS-CoV-2 KP.3与ACE2之间增强亲和力的上位效应的结构和分子基础	Feng, L.	PDF	N/A	Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2
利用CLEANSER对单细胞CRISPR筛选中的环境gRNA进行特征化与生物信息学过滤	Liu, S.	PDF	N/A	Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER
LevSeq：快速生成序列功能数据，用于定向进化和机器学习	Long, Y.	PDF	N/A	LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning
用于生物组织中单个细胞类型的全面分子图谱的关联成像	Yang, M.	PDF	N/A	Correlative Imaging for Comprehensive Molecular Mapping of Individual Cell Types in Biological Tissues
辣椒疫霉效应子AVR3a11的动力学分析证实了核心WY结构域的折叠	Tolchard, J.	PDF	N/A	Dynamics in the Phytophthora capsici effector AVR3a11 confirm the core WY domain fold
LEA_4基序单独作用并与协同共溶质结合，以在脱水过程中保护不稳定的酶。	Nicholson, V.	PDF	N/A	LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation
具有超广底物谱的PL35家族糖胺聚糖裂解酶的晶体结构与催化机制	Wei, L.	PDF	N/A	Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum
通过冷冻电子显微镜观察铁蛋白的有机-无机界面	Sen, S.	PDF	N/A	Observation of the protein-inorganic interface of ferritin by cryo-electron microscopy
甜蜜的科学：利用光学衍射断层成像技术探究果糖和葡萄糖对棕色脂肪细胞分化的影响	Anantha, P.	PDF	N/A	Sweet science: Exploring the impact of fructose and glucose on brown adipocyte differentiation using optical diffraction tomography
一种新型极端嗜盐绿色藻类——太平洋衣藻（Chlamydomonas pacifica）的描述及其作为生物技术宿主的潜力	Dutra Molino, J. V.	PDF	N/A	Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host
线粒体呼吸链的细胞内结构	Waltz, F.	PDF	N/A	In-cell architecture of the mitochondrial respiratory chain
从MetaCore网络中提取的成纤维细胞特异性蛋白质-蛋白质相互作用与心肌纤维化相关	Frahm, K. M.	PDF	N/A	Fibroblast-specific protein-protein interactions for myocardial fibrosis from MetaCore network
一个三维子宫内膜芯片揭示了胚胎源性因子CAPG和PDI在胚胎-子宫内膜交流中的作用	Tinning, H.	PDF	N/A	A 3D endometrium-on-a-chip reveals the role of conceptus-derived factors CAPG and PDI in conceptus-endometrial communication
多基因障碍阻止性染色体转变	Muralidhar, P.	PDF	N/A	Polygenic barriers to sex chromosome turnover
在患者层面建模意识障碍揭示了网络对诊断的影响与局部节点参数对预后的作用	Zonca, L.	PDF	N/A	Modeling disorders of consciousness at the patient level reveals the network's influence on the diagnosis vs the local node parameters role in prognosis
# BioRxiv 2024-09-04 Papers

标题	作者	PDF链接	代码仓库	Title